LOCUS       DAUGQX010000001       102216 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUGQX010000001 DAUGQX010000000
VERSION     DAUGQX010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102216
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.001"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(374..1492)
                     /locus_tag="VIA51_000001"
                     /pseudo
     CDS             complement(374..1492)
                     /locus_tag="VIA51_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1797..2594
                     /locus_tag="VIA51_000002"
     CDS             1797..2594
                     /locus_tag="VIA51_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8681988.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKILANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            2598..3422
                     /locus_tag="VIA51_000003"
     CDS             2598..3422
                     /locus_tag="VIA51_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8681989.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKADADAVTTLTNDESGVAEAVKTFILEEES"
     gene            3422..4972
                     /gene="ftsY"
                     /locus_tag="VIA51_000004"
     CDS             3422..4972
                     /gene="ftsY"
                     /locus_tag="VIA51_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEQ8681990.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEAVQQEDVSSEGAGSVENGPEAASVNALVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(5026..6393)
                     /locus_tag="VIA51_000005"
     CDS             complement(5026..6393)
                     /locus_tag="VIA51_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8681991.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFILFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQAEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            6721..7563
                     /locus_tag="VIA51_000006"
     CDS             6721..7563
                     /locus_tag="VIA51_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEQ8681992.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSQ
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            7565..9427
                     /locus_tag="VIA51_000007"
     CDS             7565..9427
                     /locus_tag="VIA51_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8681993.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GEVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            9446..10870
                     /locus_tag="VIA51_000008"
     CDS             9446..10870
                     /locus_tag="VIA51_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8681994.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(10969..11784)
                     /locus_tag="VIA51_000009"
     CDS             complement(10969..11784)
                     /locus_tag="VIA51_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEQ8681995.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMILSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(11784..12686)
                     /locus_tag="VIA51_000010"
     CDS             complement(11784..12686)
                     /locus_tag="VIA51_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEQ8681996.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            complement(12834..12989)
                     /locus_tag="VIA51_000011"
     CDS             complement(12834..12989)
                     /locus_tag="VIA51_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8681997.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            13223..15355
                     /locus_tag="VIA51_000012"
     CDS             13223..15355
                     /locus_tag="VIA51_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEQ8681998.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            15342..15779
                     /locus_tag="VIA51_000013"
     CDS             15342..15779
                     /locus_tag="VIA51_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEQ8681999.1"
                     /translation="MTLTNYVQEVSLADFGKSLHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            15843..16115
                     /locus_tag="VIA51_000014"
     CDS             15843..16115
                     /locus_tag="VIA51_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEQ8682000.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            16480..17412
                     /locus_tag="VIA51_000015"
     CDS             16480..17412
                     /locus_tag="VIA51_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEQ8682001.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            17409..18188
                     /locus_tag="VIA51_000016"
     CDS             17409..18188
                     /locus_tag="VIA51_000016"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEQ8682002.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            18210..18617
                     /locus_tag="VIA51_000017"
     CDS             18210..18617
                     /locus_tag="VIA51_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEQ8682003.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            18610..19038
                     /locus_tag="VIA51_000018"
     CDS             18610..19038
                     /locus_tag="VIA51_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ8682004.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH"
     gene            complement(19197..19481)
                     /locus_tag="VIA51_000019"
     CDS             complement(19197..19481)
                     /locus_tag="VIA51_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEQ8682005.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM"
     gene            19680..20606
                     /locus_tag="VIA51_000020"
     CDS             19680..20606
                     /locus_tag="VIA51_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8682006.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            20697..21983
                     /locus_tag="VIA51_000021"
     CDS             20697..21983
                     /locus_tag="VIA51_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8682007.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTASIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            22193..22405
                     /locus_tag="VIA51_000022"
     CDS             22193..22405
                     /locus_tag="VIA51_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEQ8682008.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(22502..22642)
                     /locus_tag="VIA51_000023"
     CDS             complement(22502..22642)
                     /locus_tag="VIA51_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682009.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(22778..24271)
                     /gene="lysS"
                     /locus_tag="VIA51_000024"
     CDS             complement(22778..24271)
                     /gene="lysS"
                     /locus_tag="VIA51_000024"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEQ8682010.1"
                     /translation="MSNQHIEELNDQQIVRREKMTALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVRGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGAD
                     FWPEMTVEEAIALAKEKQVPLEKHFISVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            24445..25347
                     /locus_tag="VIA51_000025"
     CDS             24445..25347
                     /locus_tag="VIA51_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8682011.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            complement(25455..26078)
                     /locus_tag="VIA51_000026"
     CDS             complement(25455..26078)
                     /locus_tag="VIA51_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8682012.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(26419..26898)
                     /locus_tag="VIA51_000027"
     CDS             complement(26419..26898)
                     /locus_tag="VIA51_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEQ8682013.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            complement(26989..27552)
                     /gene="thiT"
                     /locus_tag="VIA51_000028"
     CDS             complement(26989..27552)
                     /gene="thiT"
                     /locus_tag="VIA51_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEQ8682014.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMTLSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSNSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     regulatory      complement(27597..27693)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(27821..28669)
                     /locus_tag="VIA51_000029"
     CDS             complement(27821..28669)
                     /locus_tag="VIA51_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEQ8682015.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPGKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDSV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     gene            28994..29497
                     /locus_tag="VIA51_000030"
     CDS             28994..29497
                     /locus_tag="VIA51_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8682016.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGCQ
                     AFLVALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            29481..29867
                     /locus_tag="VIA51_000031"
     CDS             29481..29867
                     /locus_tag="VIA51_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEQ8682017.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQIQTTPSVPKADHHVRLVV
                     KEDTNTVDEKVSFGKGDTVLEVLKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNG
                     KMADKGADQITVKDGDSIEFYQEVFN"
     gene            complement(29913..30392)
                     /locus_tag="VIA51_000032"
     CDS             complement(29913..30392)
                     /locus_tag="VIA51_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEQ8682018.1"
                     /translation="MPNLYDFTVKAQDGSDISLVDYKEKVVLVVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(30385..32184)
                     /gene="pepF"
                     /locus_tag="VIA51_000033"
     CDS             complement(30385..32184)
                     /gene="pepF"
                     /locus_tag="VIA51_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8682019.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIREKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKHNPNGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIISYTEDMSHA"
     gene            32343..35141
                     /gene="ppc"
                     /locus_tag="VIA51_000034"
     CDS             32343..35141
                     /gene="ppc"
                     /locus_tag="VIA51_000034"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEQ8682020.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQDIIAEEVALLKEMLENITRR
                     MIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDELAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLNTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNIIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAERQDVRDVFYEILDEW
                     QLTKNVILAIQDHDALLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            35281..36585
                     /locus_tag="VIA51_000035"
     CDS             35281..36585
                     /locus_tag="VIA51_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEQ8682021.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            36939..38135
                     /gene="tuf"
                     /locus_tag="VIA51_000036"
     CDS             36939..38135
                     /gene="tuf"
                     /locus_tag="VIA51_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEQ8682022.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPSSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            38376..39134
                     /locus_tag="VIA51_000037"
     CDS             38376..39134
                     /locus_tag="VIA51_000037"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEQ8682023.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(39233..40468)
                     /locus_tag="VIA51_000038"
     CDS             complement(39233..40468)
                     /locus_tag="VIA51_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8682024.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISRPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTRSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(40455..41681)
                     /locus_tag="VIA51_000039"
     CDS             complement(40455..41681)
                     /locus_tag="VIA51_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEQ8682025.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FIKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLGIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLATGQTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(41681..42490)
                     /gene="yidA"
                     /locus_tag="VIA51_000040"
     CDS             complement(41681..42490)
                     /gene="yidA"
                     /locus_tag="VIA51_000040"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEQ8682026.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(42946..44247)
                     /locus_tag="VIA51_000041"
     CDS             complement(42946..44247)
                     /locus_tag="VIA51_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8682027.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEVLFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSQGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMMQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            44329..44715
                     /locus_tag="VIA51_000042"
     CDS             44329..44715
                     /locus_tag="VIA51_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEQ8682028.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            44946..47627
                     /locus_tag="VIA51_000043"
     CDS             44946..47627
                     /locus_tag="VIA51_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEQ8682029.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVEFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(47711..48706)
                     /locus_tag="VIA51_000044"
     CDS             complement(47711..48706)
                     /locus_tag="VIA51_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8682030.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRISESI
                     KATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(48770..50677)
                     /locus_tag="VIA51_000045"
     CDS             complement(48770..50677)
                     /locus_tag="VIA51_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEQ8682031.1"
                     /translation="MFFAFARFKETVNPDFCRNYLLDYQTDSYADQKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVIDDPEWNFMLNRQTYLQKLILVYLVERDERYL
                     LTAKGFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFNALTKQEESLIL
                     ASLEKQLQFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDVTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSLCLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGIFLIIDTIQAQGNHCLVSQFILDNHLDVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNSHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(50764..51585)
                     /locus_tag="VIA51_000046"
     CDS             complement(50764..51585)
                     /locus_tag="VIA51_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8682032.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYNNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA"
     gene            complement(51572..52354)
                     /locus_tag="VIA51_000047"
     CDS             complement(51572..52354)
                     /locus_tag="VIA51_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8682033.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFAFIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(52373..52861)
                     /locus_tag="VIA51_000048"
     CDS             complement(52373..52861)
                     /locus_tag="VIA51_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8682034.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKLLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(52897..54096)
                     /locus_tag="VIA51_000049"
     CDS             complement(52897..54096)
                     /locus_tag="VIA51_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEQ8682035.1"
                     /translation="MARPLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPESREAALKAADKLVQRYQDKGGFIQ
                     AWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKDLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(54096..54533)
                     /locus_tag="VIA51_000050"
     CDS             complement(54096..54533)
                     /locus_tag="VIA51_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8682036.1"
                     /translation="MIAIIVMGHGHFASGIVSALELIAGKQEKVTAIDFTTEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGATDDELGGI"
     gene            54869..55663
                     /locus_tag="VIA51_000051"
     CDS             54869..55663
                     /locus_tag="VIA51_000051"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEQ8682037.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGAIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            55688..56329
                     /locus_tag="VIA51_000052"
     CDS             55688..56329
                     /locus_tag="VIA51_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ8682038.1"
                     /translation="MKIALINENSQAAKNGIIYDALTTVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFQEYFFANAEPSELVTYLKSVLEQ"
     gene            56358..57359
                     /locus_tag="VIA51_000053"
     CDS             56358..57359
                     /locus_tag="VIA51_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ8682039.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACEAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CISFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRKKADTTTI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNHFKAYAYDRQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLANQRDIQR"
     gene            57364..57999
                     /locus_tag="VIA51_000054"
     CDS             57364..57999
                     /locus_tag="VIA51_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ8682040.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            58295..58945
                     /locus_tag="VIA51_000055"
     CDS             58295..58945
                     /locus_tag="VIA51_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEQ8682041.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLEKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            59637..60761
                     /gene="queG"
                     /locus_tag="VIA51_000056"
     CDS             59637..60761
                     /gene="queG"
                     /locus_tag="VIA51_000056"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEQ8682042.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRIYTERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GKFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF"
     gene            60830..61928
                     /gene="prfB"
                     /locus_tag="VIA51_000057"
     CDS             join(60830..60901,60903..61928)
                     /gene="prfB"
                     /locus_tag="VIA51_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEQ8682043.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKI
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            61947..62639
                     /gene="ftsE"
                     /locus_tag="VIA51_000058"
     CDS             61947..62639
                     /gene="ftsE"
                     /locus_tag="VIA51_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEQ8682044.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            62632..63561
                     /locus_tag="VIA51_000059"
     CDS             62632..63561
                     /locus_tag="VIA51_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682045.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(63871..64569)
                     /locus_tag="VIA51_000060"
     CDS             complement(63871..64569)
                     /locus_tag="VIA51_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8682046.1"
                     /translation="MPFIFRYSFFNKVLIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTSGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            64737..65501
                     /locus_tag="VIA51_000061"
                     /pseudo
     CDS             64737..65501
                     /locus_tag="VIA51_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
     gene            65609..68110
                     /locus_tag="VIA51_000062"
     CDS             65609..68110
                     /locus_tag="VIA51_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEQ8682047.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFAR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            68445..69638
                     /locus_tag="VIA51_000063"
     CDS             68445..69638
                     /locus_tag="VIA51_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8682048.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            69659..71005
                     /gene="asnS"
                     /locus_tag="VIA51_000064"
     CDS             69659..71005
                     /gene="asnS"
                     /locus_tag="VIA51_000064"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEQ8682049.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            71419..72309
                     /gene="rapZ"
                     /locus_tag="VIA51_000065"
     CDS             71419..72309
                     /gene="rapZ"
                     /locus_tag="VIA51_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEQ8682050.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            72306..73283
                     /locus_tag="VIA51_000066"
     CDS             72306..73283
                     /locus_tag="VIA51_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEQ8682051.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYPGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            73280..74191
                     /gene="whiA"
                     /locus_tag="VIA51_000067"
     CDS             73280..74191
                     /gene="whiA"
                     /locus_tag="VIA51_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ8682052.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            74324..75721
                     /locus_tag="VIA51_000068"
     CDS             74324..75721
                     /locus_tag="VIA51_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8682053.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDEHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYSHEHFNPRYAFGSQRDKDRQYNTPRAWIMQKFLNPEIVQDPRSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDTGYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVFTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            75873..77420
                     /locus_tag="VIA51_000069"
     CDS             75873..77420
                     /locus_tag="VIA51_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEQ8682054.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEADAGEFKYVQFSDHAIAPEKAKHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            77568..78290
                     /locus_tag="VIA51_000070"
     CDS             77568..78290
                     /locus_tag="VIA51_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8682055.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLTLKELELRDLIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKTPKTEILS
                     FEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEAGLLGIKKGDPVLHIIRKTYNDKNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            78309..79508
                     /locus_tag="VIA51_000071"
     CDS             78309..79508
                     /locus_tag="VIA51_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEQ8682056.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCNSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQRYLFESVASTDLVAAP
                     DYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(79605..79865)
                     /locus_tag="VIA51_000072"
     CDS             complement(79605..79865)
                     /locus_tag="VIA51_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEQ8682057.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(79980..80921)
                     /locus_tag="VIA51_000073"
     CDS             complement(79980..80921)
                     /locus_tag="VIA51_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEQ8682058.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGKCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            81315..81764
                     /locus_tag="VIA51_000074"
     CDS             81315..81764
                     /locus_tag="VIA51_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEQ8682059.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            81940..82224
                     /locus_tag="VIA51_000075"
     CDS             81940..82224
                     /locus_tag="VIA51_000075"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEQ8682060.1"
                     /translation="MRLEKIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQHLTGGDIND"
     gene            82217..83479
                     /locus_tag="VIA51_000076"
     CDS             82217..83479
                     /locus_tag="VIA51_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEQ8682061.1"
                     /translation="MIKSIATLPKPSLKEVLGLVGLALPIGGAVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKNQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCRRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYSALLPSLVAAYVASWTSHALGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFAYLLGWFKPYLSQKLPNPYFRIAFIGALLSICLMIGHV
                     GRYSGLGTNLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            83594..83941
                     /gene="rplS"
                     /locus_tag="VIA51_000077"
     CDS             83594..83941
                     /gene="rplS"
                     /locus_tag="VIA51_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEQ8682062.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            84188..84259
                     /locus_tag="VIA51_000078"
     tRNA            84188..84259
                     /locus_tag="VIA51_000078"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:84221..84223,aa:Arg,seq:cct)
     gene            complement(84222..84536)
                     /locus_tag="VIA51_000079"
                     /pseudo
     CDS             complement(84222..84536)
                     /locus_tag="VIA51_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            84944..85513
                     /locus_tag="VIA51_000080"
     CDS             84944..85513
                     /locus_tag="VIA51_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEQ8682063.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILGKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            85514..87466
                     /gene="gyrB"
                     /locus_tag="VIA51_000081"
     CDS             85514..87466
                     /gene="gyrB"
                     /locus_tag="VIA51_000081"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEQ8682064.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFLYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            87834..89558
                     /gene="ezrA"
                     /locus_tag="VIA51_000082"
     CDS             87834..89558
                     /gene="ezrA"
                     /locus_tag="VIA51_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEQ8682065.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLEHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(89690..90148)
                     /locus_tag="VIA51_000083"
     CDS             complement(89690..90148)
                     /locus_tag="VIA51_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEQ8682066.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
     gene            90375..91682
                     /gene="eno"
                     /locus_tag="VIA51_000084"
     CDS             90375..91682
                     /gene="eno"
                     /locus_tag="VIA51_000084"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEQ8682067.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFESIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(92164..93193)
                     /locus_tag="VIA51_000085"
                     /pseudo
     CDS             complement(92164..93193)
                     /locus_tag="VIA51_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(93460..95000)
                     /locus_tag="VIA51_000086"
                     /pseudo
     CDS             complement(93460..95000)
                     /locus_tag="VIA51_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            95472..101651
                     /locus_tag="VIA51_000087"
     CDS             95472..101651
                     /locus_tag="VIA51_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ8682068.1"
                     /translation="MFLKHQDVKQKNWRMRKVKKVFVSSCMLLTVGLGVAVPTGFSQS
                     NGVMVVKAAEVPATDLSRQASDSERVDESSLLQKENLSVDSFKLENLNGWEAENDTAG
                     NLGKFKDPDSSGYQNILTSSGKNISVAVAPKGSGKMNIKVTKRSNFQGGYYVGGLRTQ
                     TPVLKLNDVYRYSFTTKKLSGNSSEFKTRVKPVESNNKLGKELVIRVDNKNVSTKHDW
                     LPDISDGTHTVDFTGLDKKLSVAFRFSPRQTSNVVYEFSNINIKNISPASVPAIPSKV
                     LEGTSVLSGTAISSGDTLEKRKSFDGDILRVYKDSKIIARTVIKGNKWDVKLSKPLIA
                     GEKLDFEILHPRSQNVSKKISKQVEAKPFDPASYKEKVIAKLKPVYEATSEKITNDAW
                     LDENAKDLQKQKLEEQYISGKVAISEAGTKQEAIDAAYNKYSSQTDPDSLPSQYKQGN
                     KENEQEKGRQDLIQTRDLTLKAIQEDKWLTEQEKTIQKEEALKAFETGIESVNQTVSL
                     EQLKQRLIVYKASEKDSEKKEYPESIPNQHIPGKEKEVKAAKQEELKKLHDTTLEKIN
                     QDKWLTPDQQAEQLKQAEVTFKKGQEAIKSAQTLTQLETDLADYVSENEGKGNSIPDK
                     YKSGHKDDLVNKAEVKLKEAHEATKQAIEKDPWLSPEQKKAQKEKAKARLDEGLKALK
                     AADSLEILKVTEEAFVDKEKNPDSIPNQHKAGTADQARKQALDSLDKEVQKELESIDN
                     DNTLTTDEKAAAKKKVNDAYDVAKQTAMEANSYEDLTTIKDEFLSNLPHKQGTPLKDQ
                     QSDAIAELEKKQQEIEKAIEGDKTLPRDEKEKQIADSKERLKSDTQKVKDAKNADAIK
                     KAFEEGKVNIPQAHIPGDLNKDKEKLLAELKQKADDTEKAIDVDKTLTEDEKKEQKVK
                     TKAELEKAKTDVKNTQTREELDKKVPELKKAIEDTHVKGNLEGVKNKAIEDLKKAHTE
                     TVAKINGDDTLDKATKEAQVKEADKALAAGKDAITKADDADKVSTAVTEHTPKIKAAH
                     KTGDLKKAQVDANTALDKAAEKERGEINKDATLTTEDKAKQLKEVETALTKAKDNVKA
                     AKTADAINDARDKGVATIDAVHKAGQDLGARKSGQVAKLEEAAKATKDKISADPTLTS
                     KEKEEQSKAVDAELKKAIEAVNAADTADKVDDALGEGVTDIKNQHKSGDSIDARREAH
                     GKELDRVAQETKGAIEKDPTLTTEEKAKQVKDVDAAKERGMAKLNEAKDADALDKAYG
                     EGVTDIKNQHKSGDPVDARRGLHNKSIDEVAQATKDAITADTTLTEAEKETQRGNVDK
                     EATKAKEELAKAKDADALDKAYGDGVTSIKNQHKSGKGLDVRKDEHKKALEAVAKRVT
                     AEIEADPTLTPEVREQQKAEVQKELELATDKIAEAKDADEADKAYGDGVTAIENAHVI
                     GKGIEARKDLAKKDLAEAAAKTKALIIEDKTLTDDQRKEQLLGVDTEYAKGIENIDAA
                     KDAAGVDKAYSDGVRDILAQYKEGQNLNDRRNAAKEFLLKEADKVTKLINDDPTLTHD
                     QKVDQINKVEQAKLDAIKSVDDAQTADAINDALGKGIENINNQYQHGDGVDVRKATAK
                     GDLEKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTAEGINQELGK
                     GITAINKAYRPGEGVKARKEAAKADLEKEAAKVKALITNDPTLTKADKAKQTEAVAKA
                     LKAAIAAVDKATTAEGINQELGKGITAINKAYRPGEGVKARKEAAKADLEREAAKVRE
                     AIANDPTLTKADKAKQTEAVAKALKAAIAAVDKATTAEGINQELGKGITAINKAYRPG
                     EGVEAHKEAAKANLEKVAKETKALISGDRYLSETEKAVQKQAVEQALAKALGQVEAAK
                     TVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAALNEAKQAAIEALKQAAAETLAKIT
                     TDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIASVKEAKDKGITAIRAAYVPNKAV
                     AKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLYSKKKESKD"
     gene            complement(101837..101953)
                     /locus_tag="VIA51_000088"
                     /pseudo
     CDS             complement(101837..101953)
                     /locus_tag="VIA51_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        31737 a        18129 c        21679 g        30671 t
ORIGIN      
        1 tgatgtatac tgtcatttag aataataatc acatattgtt gtcaacgaaa cccaccatag
       61 tctataatga aagcctagta gggatgagct atataccaac tatctatcaa tccagacgtc
      121 tctactaaaa aatactccgt cttctatgaa actagaaacg gagtatttct gtttgtctat
      181 accactaaat gaacagttat atagaaaggt gattggatgt ttggaataaa catcctgaaa
      241 aaaatttgag accttcttat atcctaaact agaacgaatg tctagtgaaa taaaaaaagc
      301 gacaccatta ggatgtattt tggactaatg tcaaataagt agacagaaaa ccgtgttatt
      361 ttattacgtt aaactaattt tcttctttct gattaggggt tagtcctaga ttagccgtat
      421 gtgggttgta attgttataa aaattctcaa tgtattcaaa gcagtctaat tgaacctgtt
      481 tgatactttt tttggttgat ttgtctatgc tttaaatact tgaaaaatgc ttcagttacg
      541 gcattatcat aaggatatcc aggtttagaa aaagaatgca tgatagtgtt gtcatcaatt
      601 atttttctca attccctggc cttaaattgt gacccttggt cggaatgaaa gagaagtgtt
      661 ccttcaatct ttcttttatt aagagctaat tctagagtgt cacatgctaa ctttgcatcc
      721 atacggtgac tcagtttcca agcaatacat tttctagaat agagatcaag tattgcgcag
      781 agatagacat atttcttata tccaatagaa atataggtga agtcagtaga ccatacttga
      841 ttaggtttgt caggattaaa tttctggttg agtaagtttt gaggatacgt tttttgagtc
      901 cttttaagag ctgtttttgg cttaacggta gccattttag ggagcgccat attcttcatt
      961 agacggtaaa ttcttccttc agagattttt gtgtcgtagt ctctttgaag aatgactttg
     1021 atagacttca caccaagtct tttgtttgct ttggtataaa tctcaagtat ttgttttcta
     1081 taaatttgat tatccaattc tctttttgag ggcttatgtt ttagaaattt atagtaagtg
     1141 gagcgattga cacgtaaaac acgatacaag gttgttgtga cgtgttcaaa gcgtaaccga
     1201 taaacagcga ggagtcttac tttaagtttt gcatgaatat ggcacttgct ttttttagga
     1261 taaggttctc ctcttcaagc tgcgcattac gtttttgtag ctcttgtatt tgcttggcag
     1321 taagtacaga attatcttcg agtttgactt gggaatactg tttgatccat tttgcaagcg
     1381 cagaagcgga taccccatag tctttacaga gttcagaccg agtttttcca gtttgataaa
     1441 ggttaacaag agattgtttg aattcttcat catagcgttt aactgttgac ataggctgtc
     1501 ctttcgtttt tgtgtctttt aaaacagatt gtaacacaca aagttttgtc tacttttata
     1561 gtatacatcc agtggtcatt tataaaaata aaaaaagtag cagttcactt caaaaacggt
     1621 caggttatcg aaatataatc tggctgtttt ttacgaatgg aatgaaagct gctttttatg
     1681 atataataag aaaaattgaa cagaatgcag aaatgatggg gcttatttaa atcgttaaaa
     1741 agtgcacacc ctaaatggcg tttgcacccc cctagagtaa aaaaaggaga cattgtatga
     1801 taaaactaat agcaacagat atggatggta ctttcctagc tgaagatggt acttataatc
     1861 aagagcaact agctgcgctc ttgccaaagt tagccgaaaa aggcatttta tttgcggttt
     1921 cgagtggccg ctcgctctta gccattgatc agctctttga gccctttttg gatcagattg
     1981 ctgttattgc agaaaatggt tccgtggttc aataccgtgg tgagattcta tttgcagata
     2041 tgatgaccaa agagcagtat accgaagttg caaaaaagat tttagccaat cctcactatg
     2101 tagaaacagg tatggttttt tctgggcaaa aggcagccta tattttaaaa ggcgcatcag
     2161 aagagtacat tcaaaaaaca aaacattact atgctaatgt taaggttatt aatggttttg
     2221 aagatatgga gaatgacgcc atttttaaag tttctaccaa cttcacaggc cataccgtct
     2281 tagaaggaag cgattggttg aatcaagccc tcccttatgc cactgcagtg accaccggct
     2341 ttgattccat tgatattatc ttaaaagagg tgaataaggg ctttggtatg gagcatcttt
     2401 gtcaagcctt gggcattaag aaagcagaaa cgattgcttt tggggataat tttaatgatt
     2461 accagatgtt ggagtttgct ggtagggcta ttgctacgga aaatgcaaga cctgaaatca
     2521 aagtgatttc agaccaagtc attggccact gtaatgacgg agcagtacta acgtatttaa
     2581 aaggactagt gtaactcatg aatattagaa ttttggcgct tgatttagac ggtaccctct
     2641 acaacactga aaaaattgtc acagatgcca ataaaaaagc cttagcagcg gctagagaaa
     2701 aaggggttaa ggtggttatt accacaggtc gccctctaaa ggccatcggt aacttgctag
     2761 aagagttgga cttgcttgac cacgatgact acagtattac ctttaatggg gggttggttc
     2821 agcgaaatac aggggaggtt ttggataaga gttctctcag ttttgaccag gtttgccaga
     2881 ttcagcaagc tttagaggcg gttggcttac caacagatat tatcagtggt ggggatgtgt
     2941 atagcattcc aagtaaggac ggtaggcatt cgcagtacca tctagctaac ccactgttga
     3001 cctttattga ggtgacatct gtagcggaac taccaaaaga cattacctat aacaaaattg
     3061 tgacagtcac cgatccagac tttttggatc agcagattat aaagctatcc ccaagcttat
     3121 ttgaggattt tgaagccttt aaatcacgag atattatttt tgaaatcatg ccaaaaggca
     3181 ttgataaagc ttttggatta aacttgcttt gtcagcacct tggccttgac gctagacatg
     3241 tcatggctat gggagacgaa gctaacgact ttgcgatgtt agaatgggca ggacttggag
     3301 tagctatggc taatggtgtt tcaggagcta aagccgatgc cgatgccgtg accaccttga
     3361 ccaatgatga gtctggagtt gcagaagctg tgaagacatt tattttagaa gaggagagtt
     3421 aatgggatta tttgatcgtt tatttgggaa aaaagaaacc ccgaaggtag ctgaggaaaa
     3481 gttagaagaa aatcttttga cagaaacaac tcagaaagag gagctttctg aaaaagccaa
     3541 tgagcaagac aagattgagg cggttcaaca agaggacgtt tcttcagagg gcgcaggttc
     3601 ggtggaaaat ggtcccgaag cagcttcagt aaacgcactg gttgaggaag aaacaggtga
     3661 caatagtaat catccatcag aagataccaa tgagtttgct gccgacaaaa cagaccttaa
     3721 ggtaagtgaa cttagtcaat ctacggcatc agaaccaaaa gaccttgttg accagccagt
     3781 tgtggaacag tttccaacaa aacaagccca agctgatgcc tcaaatgatt cggcgaatga
     3841 agaagcagta gacacttcaa aagagcaatc cagtagccaa caggttatgg aagactacta
     3901 ccgtcgtaag gctgctcttg aaaaaagcct tcaagaaaaa gcagcggcaa cggttccagt
     3961 gatgccagaa gaagttccac aagaaaatca ggcctctacc tcagcagaag cttctcaaaa
     4021 caaggcaacc cacgatacca ttcctgagac agatcaagaa aaatacaagc gtagcttgaa
     4081 aaaaacgcgg actggcttct cagctcgtct gaacagtttc tttgccaatt tcaggcgagt
     4141 ggatgaagaa ttctttgaag acttggaaga aatgctgatc ttatcagatg tcggtgtaca
     4201 tgtggcgaca actttgacag aggagttgcg ttatgaagcc aaactggaaa atgcgaaaaa
     4261 accagatgcc ttgaaacgtg tgattgtgga aaaattggta gatatctatg aaaaagatgg
     4321 gcgttataat gaagccatta attatcaaga tggcttgacg gttatgcttt ttgtaggtgt
     4381 taacggggtt ggtaaaacga cttcaatcgg gaagctggct taccgttaca aacaagaagg
     4441 taaaaaagtc atgttggtgg cagcagatac cttccgagca ggggctgtgg ctcagctagt
     4501 cgaatgggga cgccgagtag atgtgccagt cattactggc cctgaaaagg ctgatccagc
     4561 gtctgttgtt tttgacggga tggaaaaagc tgtggcaaaa ggtgtagata ttctcctgat
     4621 tgacacggct ggtcgcctgc aaaacaaaga aaatctcatg gcagagctgg aaaaaatggg
     4681 tcgtatcatt aagcgcgtgc taccagatgc ccctcatgaa acgcttttgg ccttagatgc
     4741 gtcaacagga caaaatgcgc ttagccaagc caaggaattt tcaaaaataa caccattaac
     4801 aggtttgatt ttaacgaaaa ttgatggcac ggccaaaggt ggtgtagtcc tagccatccg
     4861 tcaagaatta gacattccag tcaagtttat cggatttggt gaaaaagtgg atgatattgg
     4921 agaattccac tcagaagact ttatgaaagg ccttttggaa ggtatcttat aacagcaaaa
     4981 accagtctcg ttttattgaa cgagactggt ttttagtatg tcatcttagg ctaatccttt
     5041 tttccctaaa tggtaaaaca tagcaaagaa aaagataaaa tcaagtagag caaaaatagt
     5101 aaagagaagg tagacagact ggacaccgct tgtgaattct gcttgactat ttgctatcag
     5161 tgatgccata gcagttccta gagcgccagc aaattgctgc atcatctgaa aaatggccgt
     5221 ggcatcggca tttttctcgg caggcaattc tcgaatagcc gtggctaagc tattattaaa
     5281 gcccatgtta cgcccaaacg tgaataaaat atataaaaga gtgaatggta aaagcataaa
     5341 atgtcttgtt tgaagtgtca taataatcaa tgataaacta aataaggcat ttcctaaata
     5401 aagcgaaagt cttgctcctt tttgatcata aagtttacca aaagcaggtg ctagtagagc
     5461 tccgagtaag gtaccaggta gtaacaccat accagcttga gaactattag caatcttttc
     5521 catgacaata aagtttggcg ttagaaaatt tatgcctaaa ttaatcagct ggaagacaaa
     5581 aaagggaatc aggccaaagg ttagagaggg aattttgaga atgcgaatat caagaaaggg
     5641 ttgcttagct gtgagattct tgtagaggaa gaggataaag ctgagaataa aaagccctaa
     5701 gtaatacaaa ttaacactgc cgttttctag actagtaata gctaataagg cagaagttaa
     5761 gctaatcgat agtgcaataa atgccaacca gtcaaagggt actttttcgc ttactggaga
     5821 atcttcgagg taataataag ctagaatacc tgcaatcagt ggtacaggga gtatacagat
     5881 aaaaatccat tgccaactaa aatggctaat cataaagccc ccataagtag gcccaaaagc
     5941 aggtgctaag ctaataataa gaccagcaaa tcccataaat agacctacct tatgcattgg
     6001 gacacgctct aaaataatat taaacatctg aggcattacc agaccagtac caatgccttg
     6061 aaaaatgcgg gctagcaaca tgatcgcaaa ggactgggtc agaacggcca agatggtgcc
     6121 aaatgtaaaa agacctgtgg ccataaaaaa gaggggtctt tcccgcacat tttttttcag
     6181 tgtagccgaa gtggtcatca taatcgccac tgctagtaaa taaatggtcg tcatccattg
     6241 caagctattt aagggtaact gatagactga catcagtgtc gggaaggtga cattcatact
     6301 ggtttcagac aaaattcctg aaaaaccaat gagtgctatg gcgataatcg ccataattgt
     6361 ttgttttgaa acggtttgtt gatgatgtga catgataact cctttatcta atcgattgtt
     6421 attgtatcat ataatcttaa aattgtcaga aactcttttt tgctaaatca atagatacga
     6481 ataacaatag ttgctctttc agagaatttt ttgaaaacgc ttgacagaat cttaaagaga
     6541 tgataacatt aaagcgttct cagatgtgat tacttcaggt aagcaggcta gagacataac
     6601 aatcagaata ttaaaggatg ttatcacagt tttgtgagca gggacctatt tgaaaagtgc
     6661 tttttagcga gcttttggat aggtcatttt ttattgtgat actaaaggac taggactttt
     6721 atgttgatta aacgcgtttt aaaccataat gcggcgattt cgaccaacca tcaaggatta
     6781 gatattttat tgatgggaaa agggattgcc tttggaaaaa aagttggaga tagtattgag
     6841 cttaatgcta tcgaaacatc atttgtttta aaaaatagtg acaatatgaa tcgcttcaca
     6901 gagttattta ttacggtgcc acaagaagtt gttgcttgct cagagagaat tatcaatcta
     6961 ggtaaaatta aattaggcaa aaccttagat gaaattctct atattaattt aacggatcat
     7021 attcactctg ctattgaaag gcatgagcaa ggaatgttga ttcataaccc actacggtgg
     7081 gaaattcaac gctattatcc tgatgaatat agtctagggg taaaagcctt agagctaatt
     7141 gagcgtaatc taggagtcac tctagctatt gatgaagcag cttttattgc catgcatttt
     7201 gtcaatgcta gtttggacac tccttttaag gagccacatc gcctgacgga gattgtttct
     7261 tatattgagc aaaaaatcaa aacagacttc aaaacagaat tggatgacac atccatcgat
     7321 tattaccgct ttatgaccca tattaaatta tttgctcaac gtgtgttatc acagatgtct
     7381 tacgatgatg atgatgcgga actgctttta gtggtgaaaa cgaaataccc taaagaatat
     7441 cggtgcgtct tagatattag tgaggagata aaaaagcggt acaactacca ccttaattca
     7501 agcgaacttt tgtatttgac ggttcatgtt aaacgtttag tgaaacattt aaaggagact
     7561 taatatgacg tatcaagaaa ctgccaaggc tattttagcg gcggttggtg gcaaaacaaa
     7621 tattcaacgt gtgacacact gtgtaacacg tctacgctta gtactgaaaa atgatgagaa
     7681 agttaaagat cagcaagtca aagccatttc aaatgtgatt ggcgtgatgc gcaaaaacgg
     7741 ccagtaccaa attatcttgg gcaatgatgt caataattat taccaagcct ttttaagcct
     7801 agggcatttt gacaatcaag atgaagatca ttcttcaaaa gcgaaaggaa gtatccttga
     7861 gcgcttgatt gaaaccattg ctggcgtgat tacaccgctg attccagccc ttcttggtgg
     7921 tggaatgctc aaagtggtgg gaatcttgct tcctatgctt ggcttagcga gtgcggactc
     7981 tcaaaccgtt gcctttatta acttctttgg cgatgcggct tattatttta tgcctgtcat
     8041 gattgcctat tcagcagcgg cgcgctttaa ggtgacacct gttttagcag cgacgatcgc
     8101 agggatttta ttgcatcctg cctttgttgc aatggtagca gaaggtaaac cattgacttt
     8161 atttggagca ccagtcactc ctgctagcta tggctcatct gttattccca ttttgatgat
     8221 ggtttacttg atgcaataca ttgaaaaatg ggtcaatcgc ttggtgccaa gcgtgatgaa
     8281 aagcttctta cagccaacct taatcatttt gatttctggc tttttggctt tagtggttgt
     8341 aggtcctctt ggtgtgatta ttggtcaagg gttatctaat accatgctcg ctatttatca
     8401 tgtggctccg tggctagcac ttgctatttt gggagcgatt atgccgcttg ttgtcatgac
     8461 ggggatgcac tgggcttttg caccaatctt tttggccgct tcggtcgcaa caccagatgt
     8521 cttgatttta ccagcaatgt tggcttctaa tttggctcaa ggagccgcat ctttggctgt
     8581 tgcctttaaa acaaagcaga aacaaacacg tcaagttgcc cttgccgcgg ggatttcagc
     8641 tttgctggca ggtatcacgg aaccggcact ttatggggtc acactgaaat ttaaaaagcc
     8701 actctatgca gccatgattt caggtggtct ggttggagcc tttattggtt ttgtcaatat
     8761 tgcttcttat acctttgtcg taccttctat tattggttta ccacagtaca tcaacccatc
     8821 aggcggagct aattttacaa atgctttgat tgccggaact gcgacgattg tgttagcctt
     8881 cagtttgact tggttcatgg gaattgatga agagtcccca aagcaagtga gtgttgcagc
     8941 agatatgtca caagttaaga gcggcttgtc aaccaaacaa acgttgtatg ctccaatgac
     9001 aggtgagatg ctttttctat cagaagttcc tgatgaaacc ttttcttcca agttattagg
     9061 agaaggattt gccatattac caagcgaagg tgaggtctat gccccctttg atggtgaagt
     9121 catcactttc tttccaacca agcatgctgt tgccttaaaa aacacacgtg gtgtggaagt
     9181 cttgattcat gtcggtattg atacggttga gttaaaaggg caaggtttcg agcagttagt
     9241 gtctgttggc gatgtcgtga aacgaggcca ggcacttcta aaaatggata ttgatttcat
     9301 tacttcaaaa ggctattcac tcatcagtcc tgtggtcgtg accaattcgg ctgagcagtt
     9361 ggagattatt attcaagatg acaaaaaaat ggtgactaaa gaggacgctt tgttagtcat
     9421 tttataacct aaaaggagag ggagaatggg aatttttcca aaagatttct tatggggcgg
     9481 cgcagtagct gccaaccaag tggaaggagc atttgaggca gacgcaaaag gtttgtccgt
     9541 acaagatgtt ctaccaaatg gtggactagg agaatggaca gatagtccta ccagcgataa
     9601 tttaacttta gaggcgattg atttttacca ccgctacaaa gaagacattg ctctttttgc
     9661 cgagatgggc tttaaagtct ttcgaacgtc tattgcttgg tctcgtattt ttccaaatgg
     9721 tgacgatgac cagcccaatg aagcaggttt gcaattttat gatgacttat tcgatgaatt
     9781 gttgaactat ggcatcgaac ccttagtgac cttgtcgcat tatgagacac ctctgcattt
     9841 ggccaaagcc tataatggtt ggacagatag acgtctgatt ggcttttttg agcgctttgc
     9901 tcagacagtc atggaacgct ataaggacaa agtcaaatac tggttgacct ttaacgaagt
     9961 caactcgatt ttacacatgc cctttaccag tggtggcatc atgacagaaa aagaaaagct
    10021 gagcctgcaa gatttatacc aagctattca tcatgaattg gtagcatctg ctagtgtcac
    10081 aaagctagcg catgaaatca atcctgatgt taaagttggg tgtatgattt tggcgatgcc
    10141 tgcttaccca atgacctctg atcctcgtga tatacttgct gcgcatgcat ttgaaaatct
    10201 taatctctta ttttcagata ttcatgtgag aggcaagtat ccttcatata ttaagtcgta
    10261 ttttaaagaa aatgggattg agattgtttt tgaagacgga gacaaggaat tattagcgga
    10321 acatacggtt gattttctat cctttagcta ttacatgagt gtcacacaag cccacaatcc
    10381 tgaagcttac acatctggtc agggaaatat tctaggtggt ttgtccaatc catatttaga
    10441 atcttcggag tggggttggc agatagaccc aattggtctg cgattggtct tgaatcagta
    10501 ctatgaccgc taccagattc ctttgtttat tgttgaaaat ggcttaggtg caaaggatca
    10561 gctggtgcaa accgcagatg gcagcatgac ggttcacgat gattatcgca ttgactacat
    10621 gagtcagcat ctcgtacaag ttgccaaagc gattgaagat ggcgttgagg tcatgggtta
    10681 cacttcttgg ggctgtattg attgtgtctc tatgtcaaca gcccaattaa gtaaacgcta
    10741 cggttttatt tatgttgacc gaaatgatga tggtactggt caactcacac gctataagaa
    10801 aaaatcattt gattggtacc gacaagtcat tcaaaccaat ggacgttacc ttgaggataa
    10861 tttttcctaa ataggtcttg tttaagatgg tgactctgtt cctatgctaa ctgataaaac
    10921 tcaaaaagca tttgttttga taaaaaacaa gtgctttttt attagtcttt aaaaaacgcg
    10981 gtaaacataa ggattattag gttctttggt ttgatgaacc tcagcaagtt gaaggacagg
    11041 tagatgttgt tctaagtttt tatcatattc catatgaagg cgacctttaa ctgttagcca
    11101 tgtgttgtta gggtagctgg tttgattacc tgtggtcaaa agtccgtaca ctcctgagtc
    11161 ggcaatacag tgaataatgc cgaagcggaa aaggaattgg tagttgtcat ggcccggttc
    11221 gttataaaca aagccagtgt attggatgtc acgatcaaga aactcatctg ggtagagata
    11281 gatcaattcc atcacttcca tataattttc agtggtaatg gtgaccggtt tcttgccttt
    11341 atatttatgg agttcttgac gcatctcctt ttggtaggca gactttgtaa agtaaaggct
    11401 ggtatcaggt ttgaggtatt gaatggtggt accgtcatca ctgactcccg ttttagaggc
    11461 tcccgcagcc aatgggaaag tatagccttt agcagaaacc gtggtggaat ctaaggtcac
    11521 ggtcggcaca aggagaccaa tcaaaacagg aaagaccaag ataaaaggac tcgtcagcct
    11581 tgcgattttt cctgttaaat ggctatgtac cttaatgttt ttcatccagg tatagagttg
    11641 aacaagagct aaaatgaaag ataaaatcat ggaaatataa gcaaggtaag aataccgaac
    11701 attgatgtac tgatccagtt tgccagacag ctggagatac atggttagtt caaaatagcc
    11761 agctaaaatt aaaaagcgaa tcattagagc acccccacaa gtaaacaata aacggcaatc
    11821 ataagaacgg atacgccgat aaattggaca atgaagcgtc ctttaaaagc ctttaccatc
    11881 atcataaggt ttttaatatc caccatagga ccaattaaaa gaaaggcaag aactggagcc
    11941 actccaaagg tggataataa ggaagctccg ataaaggcat cggcttcact acataatgat
    12001 agaatgaaag ccatcagcat catgatcaaa atggctgtca agggattgtg cccaatcgtt
    12061 gtcaacacac gagttgggac atatatttgc atggcagagg caatcaaggt tccaaatacg
    12121 agatacctac cggtgtcgaa gaattcatca atagcatgta ccagtgctag ataaatgcgt
    12181 tttggcaagc tttcatgaga ataatcatga aaatgcacgg gttgagcatt atccttgaga
    12241 atgttatcat ctacaataaa agctaacatt accccaagtg taatggctac tagtgcagca
    12301 ccgaccaagc gaagtatcag aaagcgcaaa gaattcccaa aagcagaata agtagcgaac
    12361 aaaacaatag gattaatgat aggcgctgtt gccagaaaag ggacggccgt ataactaggc
    12421 accttttttt ccaaaaagcg gttgatgatg ggaataatcc cgcattcaca agaaggaaaa
    12481 acaaatccaa caaaggttcc aaacagaatg cgcaagcatt tttgcttagg taggtatttt
    12541 tgaaccaatt ctggcgttac aaagacttca atacaaccag ataaaatagt tcctaggagc
    12601 acaaaaggaa gagcttcaat gataatggac ataaaaatcg caaaccattg caagacactg
    12661 ggaggaaggt tggaaaagag tgacattcac catatccttt ctagatgata aaagaggagg
    12721 ctgaaacacg aatgttcagc ctcgactgat acgttttgtt agcctgatcg ctaaaaatct
    12781 ctcaactcag tttaaacgaa tggacgatat gttaagagaa tgagacaaac tagctatggt
    12841 ttgcttggtt ttgtttgttc tgtcgttttt tctttggtcg ctagtttacc atcagtattg
    12901 acttccaaag gcttatcaaa actagggatt gatgcaaagc ctgctagcat tttttcaagt
    12961 tcatcatttt ttttatgggt aattgccata tctatgacct tctttcattc aagataagtc
    13021 tattatacta tcatttgaga acaatgccaa agcggaagtg ttgtttactt ctttcttttt
    13081 taaaattagg tattgttatt tagggtttcg tcagttattt actaaaagta gctttttttg
    13141 attctttacg caactttata ttaggacaat gtttcgctat cattttttgc attaacatgg
    13201 tttgtgttat aatagcaata ttatggaaaa taacaataat cacaacattg cagaggcttt
    13261 gtcagttagt ctccatcaaa ttgaacaggt gcttgcccta acagcacaag gcaataccat
    13321 tccctttatt gcacgttacc gtaaagaagt aacaggaaat ctagatgaag tggtgattaa
    13381 gtccattatt gatatggata agtctctcac taccctgaat gagcgcaaag caaccattct
    13441 cgctaaaatt gaggaacagg gaaaactgac agatcagtta cgaacgagta ttgaagcaac
    13501 cgagaaactc gctgatttgg aagagttgta cctgccttat aaggaaaaac gccgtacaaa
    13561 agcgacgatt gcgcgtgaag caggcttgtt cccattagca cgtttgattt tacaaaatgc
    13621 gcaaaacctt gaaacagcag cagaaccctt tgtcacagaa ggatttgcca gcccacaaga
    13681 agctctagca ggagctgtgg acatccttgt ggaggccatg tcagaagatg ctaaattacg
    13741 ctcttggacc tacaatgaga tttggcagta cagccgctta gtatcaacgc ttaaagatga
    13801 gcagttggat gagaaaaagg ttttccaaat ctattacgat ttttctgacc aagtgtctaa
    13861 catgcaagga tatcgtactt tagcccttaa ccgtggcgaa aagttaggca tcttaaaagt
    13921 gtcttttgag cataacttgg agaaaatgca acgctttttc agtgtgcggt tcaaagaaac
    13981 caacccttat attgaagagg tcatcaatca gaccatcaaa aagaaaattg ttccagctat
    14041 ggaaagacgg gttcgttcag aactcagtga tgccgcagaa gatggggcta tccacctctt
    14101 ttctgaaaat ctccgtcatc ttttgttagt gtctccttta aaagggaaaa tggttcttgg
    14161 gtttgaccct gcctttcgaa caggtgcaaa attggctatc gttgatcaga ctggaaaatt
    14221 gttgactact caggttattt atcccgtagc accagctagc caaacgaaga ttcaagcagc
    14281 taaagaaaca ctgactcagc tcattgagac ttaccagatt gatattattg ccattggaaa
    14341 cggaacagcc agtcgggaaa gtgaagcctt tgtagcagac gttttgaaag atttcccaaa
    14401 tacgtcctat gtcatcgtta acgaaagcgg tgcttctgtt tattcagcgt cagagttagc
    14461 ccgccatgag tttccagacc tcacagtgga gaagcgctct gctatttcta ttgctcgtcg
    14521 cttgcaagac ccactcgcag aattggttaa aattgatcct aaatctattg gcgtcggtca
    14581 gtaccagcac gatgtgagtc agaaaaagtt gagtgagaat cttggttttg ttgtggatac
    14641 tgtggttaac caagtcggtg ttaatgtgaa cacggctagt ccatctttat tagcacatgt
    14701 gtcaggtttg aacaaaacga tttcagaaaa tattgtcaaa taccgcgaag aaaatggagc
    14761 actgacatca cgcgctgaca tcaaaaaagt gccgcgttta ggagccaagg cgtttgagca
    14821 agcagcaggt tttctcagaa ttccaggagc caaaaatatt ttagacaaca caggagttca
    14881 ccccgagtcc tacccagcag tcaaagaact ctttaaggta cttggtattc aggacttgga
    14941 cgacgctgcc aaggcaactt tagcagcagt tcaagttccc caaatggcag aaacattggc
    15001 tattgggcag gaaaccctta aagatatcat tgctgatctc cttaaaccgg gtcgtgacct
    15061 tcgtgatgac tttgaagcac caatcttacg tcaagatatc cttgatttga aagatttgga
    15121 aattggccag aagcttgaag gaactgtgag aaacgtcgtt gactttggtg cttttgtaga
    15181 cattggtgtt catgaagatg ggcttattca catttctgaa atgagcaaaa cctttgtcaa
    15241 ccaccctagt caagttgttt cagtgggtga cttggtaact gtttgggtct ctaagattga
    15301 cttggaccgc cacaaggtca atctcagcct attgccaccg cgtgacactc actaattatg
    15361 tccaagaagt ttccctggct gattttggca aatcacttca ccacaaggct tattggaaca
    15421 agcgcctaaa aacaactggc ggtcgctttt ttccaaaaga tggtcatttg gattttaacc
    15481 ctaggatgct tgaggagcac ggtgagctta tttttcggaa aattgttcgc catgagctct
    15541 gccattacca tctttatttt gaaggaagag ggtaccatca taaagatagg gatttcaaag
    15601 atctgctagc tcaagtaaac gggcttcgtt atgtcccaac tagctctaaa tcaaagacta
    15661 atcatcatta tagttgccaa acctgtgggc aggtttatca acgaaaaagg cgtatcaatc
    15721 tggctaaata tgtttgtgga aattgccacg ggaaacttat ggaaaaaaat cagtcgtaag
    15781 actggtttta ttttgcgaaa aacaatgtaa actagtatca tagaatgagg aggtaaagaa
    15841 acgtggaaac taaattctat aaacagcgaa aaaatcgctt ggttgcaggt gttattgctg
    15901 gtttagcaga taagtatggt tgggatcttg ctctagcgcg tgtcttagcg gctcttctta
    15961 tttacggaac tggttttgga gttttgcttt atattttgtt ggccatcttc ttaccttaca
    16021 aggaagactt gcttgaagaa cgttatggcc gaggtcctcg tcgtcgtaaa gacgctgatg
    16081 tcttaaatga agaagaagat ggttggttct ggtaaataat cagttaaaat gataattcat
    16141 cacgtaagag caaccatgtg attaactgat gataataaaa tgttttgata tgtaagtaag
    16201 cgaagggtct tatcaactat gatgaggctt tttgcttttt gacttagtaa gatgatacct
    16261 ttttaaacac cataataagc actaattgct caatgatact agtaaagtat ttgtttgcca
    16321 ttgtcttatt tttgactcat atctctaaat gataaaacct agtttttaat agagctaaga
    16381 ccatttttgg tgtcgttgtt ctcatttagt agtgaaaaaa tgagtatttg caagggtcta
    16441 acggtcgatt tgtgttataa tattgaaaaa ggagaaatta tgaccgttac tgtaaagatg
    16501 ctagtgcaaa aagttaaact tgatgtggtt tatgctacag ataacttgct gtcaaaagag
    16561 ataacaacat cagatatttc acgtccaggt cttgaaatga ctggttattt tgattattat
    16621 gctccagaaa ggttgcagct atttggaatg aaagagtggt cttatcttac acagatgact
    16681 tctcacaacc gttattctgt tttaaaagag atgttcaaaa aggacactcc tgcagtggtt
    16741 gtctctagaa atttagccat tccaaaagaa atggttcaag ctgcaaaaga agaaggtatt
    16801 tcacttttaa gtagccgtgt ttcaactagc cgcttagctg gagaaatgtc ttattttctt
    16861 gacgcttctt tagctgaacg tactagtgtt cacggcgttt taatggatat ttatggtatg
    16921 ggggttctta tccaagggga ttctggaatt ggtaaaagtg agactggttt agaattagtt
    16981 aagcgagggc atcgtttggt tgcagatgac cgtgtggatg tctatgccaa agatgaagaa
    17041 accctttggg gagagccagc agagatcttg cgccacttgc ttgaaattcg tggggtaggt
    17101 attattgatg tgatgtcgct ttatggagct agtgctgtga aggactcatc acaagttcaa
    17161 ttggccattt accttgaaaa ctttgaggct ggtaaagttt ttgatcgtct cggaaacggt
    17221 aatgaggaga taactttctc aggagtgaga atccctcgta ttcgtattcc ggtaaaaaca
    17281 ggtcgaaatg tttcagtggt tattgaagcc gctgcgatga atcatcgggc taaagaaatg
    17341 ggctttgatg ctacaaaaac ttttgaagat cgtttaactc aactaatcac caaaaatgag
    17401 gtgagtcaat gatcaatccc attgccttaa aatgtggtcc actagccatc cactggtatg
    17461 ctctatgtat cttgtcagga cttgttttgg cggtttactt agcatcaaaa gaagcaccca
    17521 aaaaaggaat atcatctgat gctattttcg attttattct gattgctttt ccacttgcta
    17581 ttgttggtgc aagaatttac tatgttattt ttgaatggtc ttattatgtc aagcatttag
    17641 atgaaatcat agccatttgg aatggcggta ttgctattta tggcggtctc attacaggag
    17701 ctcttgtact tttggcttac tgttataaca aggtgctcaa tcccattcat tttttagata
    17761 ttgccgcacc aagtgtcatg gtcgctcaag ctatcggtcg ctggggaaat tttatcaacc
    17821 aagaagccta tggtaaagct gtgagccagt taaattactt accaagcttt attcaaaagc
    17881 aaatgtttat agagggaagt taccgcattc cgacctttct ctatgaatca ctttggaatc
    17941 ttttgggctt tgtcattatt atgatgtggc gtcgtaagcc aaaaagtcta ttagatggag
    18001 aaatctttgc attttactta atttggtatg gtagtggaag actagtcatt gaaggtatgc
    18061 gaacagatag tcttatgttt ttaggtattc gcatctccca atatgtgtct gccttattaa
    18121 ttattattgg cttaatcttt gttataaaaa gacgtcgtca aaaaggaatt tcttattatc
    18181 aagaataagg atagaaaaag gagaaactta tggacttagt tggaatctca ctgatgatta
    18241 ttgcactcgc atttgttgct ttggtgattt tcttgattat tgtattaaag aaagtctcag
    18301 aaacaattga tgaagccaaa aaaacgattt ctgtattgac aagtgatgtt aatgtgacac
    18361 ttcatcaaac taatgatatt ttagcaaaag ctaatatcct tgttgaagat gttaatggta
    18421 aagtagcaac catcgatcca ctgtttgttg ctattgctga tttgtcagaa agtctttcag
    18481 atttaaatag tcaagcaagg cattttgggc aaaaagcaac taatgctaca ggtaatgttt
    18541 caaaagctgg aaaattagca ttagttggta aagtagcctc aaaagtattt ggaaaaaaag
    18601 gagaaaagca tgaataaaag tttcaaaaac ttagtgattg gagctgtttc aggagtagcg
    18661 gcagcttact tcttatcaac agaaaaaggc aaggctttga aaaatcgtgc tgaaaaagct
    18721 tatcaagcct acaaagaaag tccagatgat taccaccaat ttgctaaaga aaaaggtagt
    18781 gaatacagcc atttagcacg tgacactttc tatgatgtga aagataagtt ggcttctggt
    18841 gacttaacta aagaggacat gttagacttg ctcaaagata aaacaacagc tttcgtgcaa
    18901 aaaacaaaag aaacccttgc cgaagttgaa gcgaaagaaa agcaagatga tgttatcatt
    18961 gatttaaatg aagaagacat catcattgac tatactgaac aagatgagcc tgttagtgat
    19021 acactagata aacactaact aaaacgacct aaaacataga agaagaaaag attgaaggat
    19081 ctgatcacta gtcccgatgg ttagttttag gctaactgaa gaagggggga ttgtggcttc
    19141 aatctttttt tgtttttgac acaaaaaaaa gagtcacgta aaacggactc tggaagttac
    19201 atcagtaatg atttgataac cttggcgaat aaggaagtaa tgcctaagct gatgatgctt
    19261 gcaaataaga aagcaaacat tggcgctaaa ttcattacga gcaggacaaa tgcaaataaa
    19321 acggtaataa ggctgaaact agcgatacga gcaaagaaga ctaattcttt tagctttgca
    19381 ctttggccat tgaactcttg aaaatctcga aatttacttt gagattcttg gtaagaatca
    19441 tcctgttcaa ccgaattatg cttctttaac ggtgcaggca tagtcctctc ctttacttaa
    19501 catactaagt aattctatca taaaagtctc ttcttgtcat ctttttttaa aagatttgaa
    19561 aagatttact aatgacaagt gacttatcat gctataacag taaggggact agcttaacgt
    19621 ttgggctttt gcaagaaata tgcttaaggt cttaaaattt ttggtataat aaagcttata
    19681 tggaaaaaat aattattaca gccacagctg aaagcattga gcaagtcaaa gctttattag
    19741 ctgctggtgt tgatcgtatt tatgttggtg aagccaatta cgggttacgt cttccccata
    19801 atttttctta tgatgaattg agacaaattg ccaaactagt gcatgatgca ggcaaagagt
    19861 tgacagtagc ttgcaatgct ttgatgcatc aagatatgat ggatcagatc aaaccctttt
    19921 tagacttaat gatagagatt gctgttgatt atcttgtggt tggtgatgca ggtgtgtttt
    19981 atgtcaataa aagggatggc tataacttta aactgattta tgatacctct gtttttgtga
    20041 cttctagccg tcaggtaaat ttctgggggc aacatggtgc tgttgaaagt gttttagcaa
    20101 gggaaatccc atcagcagag ttattcacct tagctgaaaa tttggaattt ccagcagagg
    20161 tgctagttta cggcgcctcg gtgattcatc actcgaaacg tcccttgcta gaaaattatt
    20221 accattttac aaagattgat gatgaggtta gtcgtgaacg aggacttttc ttggcagaac
    20281 caggagatgc tagcagccat tactccattt atgaagacaa tcatggcact catattttca
    20341 ttaataacga tatcgacatg atgtctaaat tgggtgagct gtatgcgcat ggcttaactc
    20401 attggaagct agatggcatt tactgtccag gtgatgattt tgtcgctatt actaaattgt
    20461 ttattcaggc taaaacctta ttagaagctg ggcaatttac ccaagaagaa gctgaaaagc
    20521 ttgatcaagc agtgcatgcc catcatccag ctggccgtgg attagatact ggcttttatg
    20581 agttcgatcc aaaaaccgtt aaataagtaa tccttgtctt gagtgagtgg gcaagacagg
    20641 gttatgacac cattacacag gtaatctacc tatcttgaaa atagaaagaa tatcacatgt
    20701 cacatatgaa aaaacgtccc gaggtcttat cacctgctgg aacacttgaa aaattaaaag
    20761 ttgcgattga ctatggcgca gatgctgttt ttgttggagg gcaggcctat ggcctaagaa
    20821 gccgcgctgg taacttctct atggaagaat tgcaagaagg cattgattat gcacatgcgc
    20881 gtggagctaa ggtctatgtt gctgctaaca tggttaccca cgaagggaac gaaattggtg
    20941 cgggcgagtg gtttcgtcaa ctgcgtgata tggggcttga tgcggtcatt gtttcagatc
    21001 cagccttgat tgttatttgt tcaacagaag ccccaggttt ggaaattcat ttgtcaacgc
    21061 aagcttcatc taccaattac gagacctttg aattttggaa agccatgggc ttgacccgag
    21121 ttgttttagc tcgcgaggtt aatatggccg agttagcaga aatccgcaag cggacagatg
    21181 tggaaattga agcctttgtc catggagcca tgtgtatctc ttattcaggc cgctgtgttt
    21241 tgtcaaacca catgagtcac cgtgatgcca acaggggcgg ctgctcacag tcttgccgct
    21301 ggaagtatga tttgtatgac atgccatttg gaggagagcg ccgctcctta aaaggggaaa
    21361 ttccagaaga ctattctatg tcctctgttg acatgtgtat gattgaccat attcctgacc
    21421 tgattgaaaa tggggttgat agcttaaaaa ttgaaggccg aatgaaatct atccactacg
    21481 tctcaaccgt aaccaactgt tacaaggcgg ctgtagatgc ttacatggaa agcccagaag
    21541 ctttttatgc tatcaaagag gaattgattg acgagttgtg gaaggttgcc cagcgcgagt
    21601 tggctacagg tttttactat ggtatcccaa ctgaaaatga acaattattt ggtgctcgcc
    21661 gcaaaattcc acaatataaa tttgtcggag aagtagttgc ctttgactca gctagcatga
    21721 cagcgagcat tcgtcagcgt aatgtcatca tggaaggcga tcggattgaa tgttatggac
    21781 caggtttccg tcattttgaa acggttgtta aggacttaca tgatgcggat ggccaaaaga
    21841 ttgaccgtgc cccaaatcca atggaactct taaccatctc tttaccgaga gaagttaagc
    21901 caggggatat gattagggct tgcaaggaag gtctggttaa cctctatcaa aaagatggca
    21961 ccagtaaaac tgttagaaca tagtaacaag aaatactaga ggccctcttt ttccaaatgg
    22021 tatacgacca tagttgggaa aagagagcct gttttttttg aaaattggat atcacaatag
    22081 cttattttct caaaacttga tagaataata ggagaatgag tcataaaaaa agtgaaaaaa
    22141 agatgatttt ttccacttta atttcgaata gtatagatga ggaggaaaac taatggcaga
    22201 atttacattc aacattgagg aacatttact caccttatca gaaaatgata aaggttggac
    22261 gaaagaattg aaccgcgtca gctttaatgg cgcagaagcg aaatgggata tccgcacgtg
    22321 gagtccagac catacgaaaa tggggaaagg cattactctt actaatgaag aatttaaaac
    22381 catcttagac gcttttcgta agtaatgtta ccttaatcga aacataatcc ctcgttcgcc
    22441 cctgtccttt taacctggtg atgacatcgc taggttaaaa ggacaggggc gaatagaagg
    22501 attatttttt tgaattgagg cgatcagcaa ggccgacaag taccaaaatt aagcctagcc
    22561 caagaaaaat ccatttggca gctaaaaggc cataaagcaa gaagatagca gcactaatgt
    22621 aggagatata ttctttggtc atcttgttaa gtcactttct ataagctact gttaataaac
    22681 cagtcttcat ggtaatgaag actggttaga gataataaaa cgttatgtta tattgccact
    22741 tatcggtttt aagatatgaa tacaaatctt aaaaaagtta aggtttcatc gttgggaata
    22801 aaagcacatc tctgattgtt gttgtgtttg ttaataacat gcaaagacga tcaatcccga
    22861 ttccgagtcc accggttggc ggcataccat attcaagagc ttcaacgaag tcgtagtcaa
    22921 tgccagttgc ttcgtcatca ccaagttctt tagcttgtgc ttgtgcttca aaacgagata
    22981 attggtcaat gggatcattc aactctgtga aagcattggc gtattctttg gtcatgatga
    23041 aaagttcgaa gcggtcggtg aagcgggtat cttctggatt cttcttagcc aaaggcgata
    23101 cttcaacagg atgaccaaac acaaaggttg gttggaccaa ggtttcttca acaaattcct
    23161 cgaagaaagc gttgatgata tgtccgacac ttatgaagtg tttttcgagt gggacctgtt
    23221 tttctttggc aagtgcaata gcttcttcga cagtcatttc aggccagaaa tcagcacctg
    23281 tcacttcctt gatagcatct accatgtgaa cacgtttgaa aggttcattg atacggattt
    23341 cagttccttg ataatcaata gggccatcac ctctaacagc tttagcagca tgttggataa
    23401 tgccttctgt caggttcatg atatcaagat agtctgcata ggcttggtaa acctcaatag
    23461 aagtgaactc aggattatga gtagcatcca ttccctcgtt acggaagata cgaccaattt
    23521 catagacacg ttccatacca ccaacaatca aacgtttcaa atgaagttct gttgcgatac
    23581 gaagcaccat atcaatgttt tgagcattat ggtgagtaac gaaaggacga gcagcagcac
    23641 caccagcctc gttatgaagc acaggcgttt ctacttctag gaaatcaaga ccgtctaaat
    23701 aacgacggat ttctgaaatc attttggaac gggtcacgaa gcggtcaaag ctttcacgat
    23761 ttgaaattaa atcaaggtga cgcttacggt aaatggtttc aatatcagtt aatccgtgga
    23821 atttttcagg aagaggacga agtgatttag aaaggtgagt caacttggtt gccttgattg
    23881 acaactcgcc catgtctgta cgcatgactt cgccttcaac gccgataaag tcgcctaaat
    23941 cggctttttt gaagatttca tagttgtctt cgccaacaga gtccttgcga acataaagtt
    24001 ggatttggcc ttcacggtct tgaagatgag caaaaccaac cttacctttg ccacgttttg
    24061 tcatcaagcg gccagcaaca atagctgttt cgtttaactc atgtaattct tcttttgttt
    24121 tatcagcata cttttctttt aattcagcag aattggctgt gcggtcaaag cgtttaccga
    24181 aaggatcaat tccttgttca gccagcgccg tcattttttc acgacggaca atctgttggt
    24241 catttaattc ttcgatgtgt tgattagaca tattttcctc caatacgatt tcctttccat
    24301 tgtatcataa aaggggctag aatacaccta tatttcgttg gaaaatgcga ctgcagcggg
    24361 gcattttttt gaaaatgaaa ttgaaaagcc taatggaaaa tagtataatg attgggatat
    24421 taaactagaa aagaaaagag actcatgatt actgctattg tttttgatgt ggatgacaca
    24481 atttacgacc agcaagcgcc ttatcgaatc gccatggaaa agtgcttccc agattttgat
    24541 atgtcagtaa tgaatcaagc ttatattcgc tttcgtcact attcagatgt tggattccca
    24601 agagtaatgg caggggagtg gaccacagaa tatttccgat tctggcgttg caaggaaaca
    24661 ctgcttgagt ttggctatcg agaaatcgac gaagctgcgg gagtacattt tcaagaagtc
    24721 tatgagcacg aacttgagaa cattaccatg ttagatgaga tgcgcatgac ccttgacttt
    24781 ttaaaatcaa agaatgttcc tatggggatt attaccaatg ggccaacaga acatcagctg
    24841 aaaaaagttc gtaaattagg gctttatgat tatattgatc ctaagcgtgt cattgtgagc
    24901 caagcaacag gctttcaaaa accagaaaaa gaaattttta acctggcagc agaacaattt
    24961 gacatgaacc cacaaaccac actatatgtt ggggactctt atgacaatga tatcatgggt
    25021 gcctttaatg gtggttggca ttccatgtgg tttaatcata gaggtcgtca gctaaaacca
    25081 ggcactaagc ctgtttatga tgtggctatt gataactttg aacagctctt tggtgccgtt
    25141 aaagtactct ttgatttacc tgataataaa tttatttttg atgtcaatga caagaaaaat
    25201 ccaattttac agatgggaat caataatggc ttgatgatgg cagcagagcg tttacttgaa
    25261 agcaacatga gcattgacaa ggtggttatc ttgcttcggt taaccaagca acaagaaaaa
    25321 gttttgcgct taaaatatgc cagatagatg aaaccataat agcccactag ataataataa
    25381 aaaaagctag caaagtgagt gtcttgtcag taagagatca atgtgttagc tttttttatt
    25441 attttctagt ggttttacac ctctagaaaa gatttatcat tccaaattaa acagtcataa
    25501 gttaaataat ctttagtttc aagaatagta agactggcat tatctaagcc acctttagcg
    25561 agtaaaagag caggttcaaa acctaataat gagcgaatag ttgctgttaa gttagcgccg
    25621 tgtcctacaa taagaacgtt ttgataatgt ttatctttaa acgattggat aagatggcag
    25681 acacgttgag tcgtttggta aattgattca gcctcgaact gatctggttt gaactgggct
    25741 agattctctc gaaaagccag catttgttgg ggatatatag ctgccattgt tgctatttta
    25801 gccccttcca atttacctaa tctccactcc cgaagctggt cggtgtggta aagttttggc
    25861 tgttggtcaa aagcatctaa gataatagct gctgttgcca tagctctttg aaggtcgcta
    25921 gtataaacgg catcaaaagc caccttagct aactctttgc caagtaagtg aatttcgtct
    25981 tttgcctctt caagtaatgg cgaatcgccc ccagcgcctt gaaagcgacc ttctaaattc
    26041 caaagggttt tcccatgtct tacaaaatat aatttcattt aagcctcctt ttagagataa
    26101 ctgatgcgag cgctaaaaat aaaaaagtaa ccagaaaaag tttaggcatc accaagcaaa
    26161 aataatacct atagtgaaaa gataaagtaa aaaagcgtag tataagtgta taatagctag
    26221 gttctgatta aagtgtaaag cccatattag atctaagaca aatcgacctg aatttgtcgt
    26281 gatatcaagt ctctacaaaa gaaaaagatt aacaggatca atgttaaagc agttgagatc
    26341 aaaataatac taaacaaaga ctagcttaat caaggcgaaa aacttaaaaa agaaaccaga
    26401 taaagttggc agtagtgttc attttctctt ctttaaatca gcaaagcttg cgccaacgaa
    26461 atcagctaga gcctggctag aaatctttat agaacgccca acttcaccag ctgaaacgat
    26521 tatttgacct ttttccagtg cagtttggtc aataaaaata ggatatgaat gtttttgacg
    26581 aatcccaaca ggattattgg caccgtgaat atagcctgtt gtcttttgca agtctttttg
    26641 aggaaccatg gacacttttt tgttacctga tacttttgcc aattgttttt ctgataagtg
    26701 ttctgttaat ggaataatgc caattagagg acctgtttga tcaccagtca gagcaagtgt
    26761 cttgtaaata tctgatggtt gaagatcatc tggaaagtcg ccttctaaag cattaagctt
    26821 gagtccttga tgagcaatat tagccttatc gaggatttgt tctactaagg tttttttgag
    26881 ttttgttttt ttagccatat caagtcctta cctttatcta aacataaaaa aatggtataa
    26941 caacattatt ataccatttt tttaatgtaa gattcaaatg actaaaaatt agtctttggg
    27001 atcaaataat tgaggatgaa ttggtaaagc aatcattaac gctaaacatg ttattaaaaa
    27061 agttaggaca ccagctgtac cattaacgct aaaagaatac cagacagcgg acatgccttt
    27121 aggggcgtaa ctgccccaga aaatgattcc tgcaaggaag tgccacaagt aacgtactgt
    27181 aacggctagt aaactagcca ttattgcaag aaaaacggca aaaaaggttt gttgtcttct
    27241 taaagtttta atcaaactat tagagaaact accggctaat cccatagagg taaaggctaa
    27301 gatatattca ataaagactt gggacatgct gagatagtaa acttttccaa gtacaaagtg
    27361 aagtagcccc caaatgagac ccgccaacat gccgtacttt aacccacggc gcaaagagaa
    27421 aataaccagt gcaatagcac cataagaagg actaaaccag ccagcaaaat ctggaataaa
    27481 tgaaagggtc atcgccaatg cagcaaaaat agcagcttcg ataaggtatt tgacattggt
    27541 gtttggtgac ataaaaaact ccttttgtgc acaaaaagag tatcgctttc caatcattga
    27601 ttattggtca caatccctac gcttgtacta acaagatcag gtcctcagga tttcgcaatt
    27661 gcgatctcag ccaaagcact cctttgtgaa atattatagt gctttcatta tatgatgaga
    27721 taatctcctt gtcaaggata aggggtttta aattattgac ctagagtttt tcctggtaag
    27781 atgtaaacta taaaaaaaga ttagccatga tgctaacctc ttaattgttg gagttgccaa
    27841 ataacttctc aaacgttttt ttagtgtctt ttgttacggc aatttgattt aaatctaaag
    27901 cattgttaaa accactgaga taaccttgtg aggtgtattg gtgtaaatcg taatctaagg
    27961 ttgtattagg agcagcctca taatagccag aatcactacc ataagtcgga atccatacag
    28021 aatcgaaacc ttttgttgaa atatcttgtt ctgccataaa ataagttcca atatagagac
    28081 caacattttc agcaccaagt tttttaagct cttctcggaa ggctgttacg cctttattca
    28141 tatctttcat agtggcttct tcgacatcaa tccagtagta agttggatta tagggagcag
    28201 cgtttttgta gaaagctcgg gcctcttctt tcatctcttt agtactacga ccaagtgcgt
    28261 aactgtaaac agctacagga acatttcgtt tttgaaattc tttgatatgc gttttaaaag
    28321 atttgtcaat tccagttgta aaagcagcgt tgttatgagc tgtaatttgc gatcctccat
    28381 agacacgtac aattgcgcca gagatgtgac gtgacaatgt gtcataatca atttcttcag
    28441 ggagttgcca gccggaaaca tcaacaatag gatttaaaat aaagtcttcg gtttcagaag
    28501 tgctagtttt tgctttacca ggattactgg ttgcaatagg aatatgactc ttagcgtctt
    28561 caacttcttt ttgtttcgca tgattagctt gtctttttcc gataatcaat accattgcca
    28621 gtaaaataaa gaagactagc acaacaatag gttttatttt tcttctcatt aactgttatt
    28681 gtaccctaat tactaaaaaa aatcaaaata tcctaactgt tttcttatat tgtcttgcat
    28741 tttaaggtat tctctttgag aagttacaaa tgagatcctc tctaactatg tcaagtttat
    28801 gtcactatct cttatagttg gtagctatat tctttacaat attagtttag tctttgacta
    28861 tatcatgaca gtcagcaagt actgttttgt tatttaattc tcatgttatt atcatttgat
    28921 aaataagtga gctccaaact ggtaaacgct ctgtaaatct gtcataatag agaaaaaaac
    28981 gaggaagaag tttatgtcag ctaagcttat gagtcgcatt gctatcatgt cagccctatg
    29041 tgttgtgttg agaatggttt ttagcagcct gcctaacgtg cagcctgtga cggcattttt
    29101 actcagttat cttctttact ttgggttagc cgaggctgta ttagttatga tgttgtgctt
    29161 gtttttatca gcctttttgc tgggatttgg cccttgggtc ttttggcaag ttacttgttt
    29221 tgtgcttgtt cttttattat ggcgttttgt cttgtaccct ttgtctcagc aattccccaa
    29281 atatcagctt ggctgtcagg ctttcttggt cgccttatgt ggcctccttt atggggtgtt
    29341 gatagatact tgttttgcgt atttgtatag tatgccttgg tggagctatg ttctagctgg
    29401 gatgcctttt aatatagcgc atgctttatc aactctcgtc ttttttccag ttgtgatgat
    29461 gttatttagg aggttaatcg gtgaacaaaa gatttaaaac aggatttcta gcgcttgttg
    29521 ctatgctact tgttgcttgc tcgcaaggaa caaaacaaat acagacgact ccaagcgttc
    29581 caaaagcaga ccatcacgtt cgcttagttg tcaaagaaga taccaatact gttgacgaaa
    29641 aagtttcttt tggaaaagga gatacggtgc ttgaggttct caaagataat tatgaggtta
    29701 aagaaaaaga tggttttatc acagcaattg atggtatcga gcaagacacg aaagctaaca
    29761 aatactggct ttttaaggtg aatggaaaga tggcagataa gggtgccgat caaattaccg
    29821 ttaaagatgg tgatagcatt gaattttatc aagaagtttt taattagtaa ctataatata
    29881 aaatagactt ggcacgccaa gtctatttta tattaaccaa gaagtgcttt aaggtcttct
    29941 tcaattagtt taggatctgt ctttgaggaa tagcgtttaa tgacttgacc attttggtca
    30001 atgagaaatt tagtgaaatt ccattcgatg cgtttcccaa ggggaccact tttttcttct
    30061 tttaaccagg tgaacaaagg atcagcgtct ttaccattca ctttgatttt tgcaaagcga
    30121 gggaaagtag tgtgataggt cagactgcaa aagtgattaa tctcctcagc atctcctgga
    30181 gcttgattta aaaattggtt gcaaggaaaa tctaagacct caaatccctt gtcatggtat
    30241 gtgtcatata gtgcttgcaa ggcctggtat tgtggggtta gcccacattt ggtagctgta
    30301 ttcacgacca aaaccacttt ttctttgtag tcaactagtg agatgtcact gccgtcctga
    30361 gccttaaccg taaaatcata gagattaggc atgtgacata tcctcggtgt aactgataat
    30421 ttggtcaacg gtatcactca agaattgaat ggtatctcga agaggctttt cagtggcaat
    30481 gtctgcccca atgagcattg cagtatcaag aggcgtacgg ctgccacctg attttaggaa
    30541 gtcaagccac tccttggcac catttggatt atgtttaagg ttgaggtaac cagctgttga
    30601 aataacaagc ccagcagaat aggtataact atataagccc atgtagtaat gtgcttggcg
    30661 catccaggta agagctgcgt catcgtcaat gtcaacggca tctccccaga agtctgttaa
    30721 gacctctttc atcatcgcat ttaattggtc agctccaaag gtaccgcctt cttcaataag
    30781 ggtgtaaacc ttacgttgga aagccgcttc caataggtga gtgatgaagt tatgaaagta
    30841 agtatctgtt aaacggtgag caagggcaaa acgtttttga cgagggtcat caaactgatg
    30901 ttccaagtaa tcactaagca tcaattcatt aaaggtcgat ggcgcttcga cgtaataagt
    30961 tgacatatgg gtgttgaagt aactttggtg attatctgaa aaaatgaatt ggccagagtg
    31021 accgatttca tgaataaggg tataaacatc agacattctt ccagtccaac tcattaagac
    31081 atacggatga accttgtagg gatcagcggc ataaccacca gaatccttat tggcgttagc
    31141 agcaaagtca acccagcgtt ctgtctgata acgttcgatt tctttcgtgt attcttgccc
    31201 taatggggct agagatttca tcacgaggtc ataggcacca tcaatgctga cctctggatt
    31261 gagatcattg tcaatatcta gcttccagtc agcaaaagtc attttctcaa gaccattgac
    31321 ttgggcgaca tgttttaaga atttctgagc aaccggtcca aattcagtca tgatgaggtc
    31381 aatttggcgg tcgaacaagc tacgatccac ttcctgttca gctaggaggt aatcaaagac
    31441 agaagcgtag cctttcatat ccgctaacaa tttttcagat ttaaccttgg ctaagtaagc
    31501 cgctgcagct gtattttggt gtttacggag accttttgaa aaagagcgga aggctttttc
    31561 acgaatctca gcattttcgt gattttgata gaaattttcg taagaaacaa agctattttt
    31621 ataggtttta ccatccacct caaaatcatc catgtcaaag tcaccagccc gcattttggt
    31681 gtaaatatca tagggcgcat tgataacctc gcgtaagtta gccaaagctt tttccacatc
    31741 aggacttaag aggtgttctt tttgaatttt tgccatgcga atagctgcgc tgaaataagg
    31801 gttcttttct aatgtatcta acacgtcaag gtcggcattg gctaaggcgg tgtcaaagaa
    31861 gctaagggca acgctagctt tagtcatgaa atcatcgcca gcctgagcaa tttgagcaaa
    31921 actttcatct gaaaagtcag tggtttgagg cataaaggca taagtgccaa tatgactcat
    31981 ttgaatataa atatgctcaa tttctattaa ggcctgagtg aaatcgtcca ccgacgttaa
    32041 gcggccttca taattgcgct taaacaggtc aatatcttgt aaggcttttt caatagcgag
    32101 taaaaaatct tggcggtctt tgtagagcgc tgttagatcc caaagttcat tttcagggaa
    32161 ttctgaacgt tttttcaatt ccatagttgt ctccttaaca atatactcaa gactagtata
    32221 acagaatttt agtggaatat ggagactaaa cctatccaaa cattctttaa aataaagcgc
    32281 ttacttttgt taaaaaacaa acgttatgaa catgatcact tttatttttg gtaaaaagtg
    32341 gtatgataga agaaactagc aaagaaggag atggtcattt gccacttaaa aagttagaga
    32401 gtagtaacaa tcaagatatc attgctgaag aagttgctct tttgaaagaa atgttggaaa
    32461 atatcacacg acggatgatt ggagatgatg cgtttacagt tatcgagtct attatggtgt
    32521 tatctgaaaa acaagattac atagaattag aaaaagttgt cgccaatatt tcaaatcaag
    32581 aaatggaagt gatttccagg tatttttcta ttttaccctt gctaatcaat atttcagaag
    32641 atgtcgattt agcctatgaa atcaattatc aaaataatac ggatactgat tatttaggaa
    32701 aattagccct aaccatcaag gatcttgctg gaaaagataa tggtaaagac attttggagc
    32761 aggttaatgt ggttcctgtt ttaacagcac atccgacgca agtacaacgt aaaacgattc
    32821 tggaattgac aactcacatt cataaacttc tgcgcaaata ccgtgatgct aaggctggtg
    32881 tgattaatct tgagaaatgg cgtcaggagc tatatcgtta tattgaaatg atcatgcaga
    32941 cagatattat tcgcgagaaa aagcttcagg tgaaaaacga gataaaaaat gtcatgcagt
    33001 attacgatgg ttctctcatt caagcagtga ccaagttgac aacagagtac aaaaacttag
    33061 cccaaaaaca cggtctagag ttagacaatc ccaaacccat taccatgggg atgtggattg
    33121 gtggggaccg tgatgggaac ccctttgtca cagctgaaac cttgtgcttg tcagctacgg
    33181 ttcaaagtga ggttatcctc aattactaca ttgacgaatt agcagccctt taccgaacat
    33241 tttcactgtc gtcaaccttg gtacaaccca actcggaagt ggaacgttta gccagtttgt
    33301 ctcaggacca atcgatttac cgtggaaatg aaccttatcg cagagctttt cattatattc
    33361 aatcgcgtct taaacaaaca caaattcaac taactaatca gccagcagct cgtatgagta
    33421 gtagtgtggg actaaacaca tctgcttggt cctcaccagc tagtttagaa aatcccatct
    33481 tagcctatga ctctcctgtt gattttaaag ctgatttaaa ggctattgag cagtcgctac
    33541 ttgataatgg caactccgct ttgattgagg gggatttgcg agaagtcatg caagctgttg
    33601 atatttttgg cttcttctta gcaagcattg acatgaggca agactccagt gtccaagaag
    33661 cttgtgtggc agagttatta aaaggagcca atattgttga cgattatagc tctctttcag
    33721 aaactgaaaa atgcgatgtt ctcttacaac aattaatgga ggagccaagg actttatcct
    33781 cagcggcagt tgctaaatca gacctattgg aaaaagaact ggctatctat actacggcac
    33841 gagaattgaa agataagctt ggagaagagg ttattaaaca acatattatt tcacatacag
    33901 aaagtgtctc tgatatgttt gagttggcca tcatgcttaa agaagtggga ttggttgacc
    33961 agcagcgggc tcgtgtgcaa attgttcccc tctttgaaac cattgaggat ttagataatg
    34021 cccgtgacat catggcagcc tatttaagcc atgacattgt caaatcttgg attgcaacga
    34081 atcgtaatta ccaagaaatc atgttaggtt attctgacag taataaagat ggtggctact
    34141 tggcatcggg ttggactctt tataaagctc agaatgaatt aacggctatt ggtgaggaac
    34201 atggagtgaa gatcaccttc ttccatggtc gtggaggaac agttggtcga ggaggtggcc
    34261 cttcttatga tgccattact tcacaacctt ttggttccat caaagatcgg attcgtctga
    34321 cagagcaagg ggaaattatt gaaaacaaat acggcaataa agatgtggct tattaccatt
    34381 tagaaatgtt gatttcagct tctatcaatc gtatggtgac tcaaatgata acagatccta
    34441 atgagattga tagttttcga gaaatcatgg atagcattgt tgctgatagc aatatcattt
    34501 atcgaaaatt ggtttttgac aatccccatt tctatgatta tttctttgag gcaagtccga
    34561 ttaaggaagt ttccagtctc aacattgggt caagaccagc ggcccgtaaa acgattacgg
    34621 aaattacagg cttgcgtgcc attccttggg tcttttcatg gtcacaaaat cgcatcatgt
    34681 ttccaggttg gtatggggta ggttcagcct ttaaacgtta tattgaccga gcacaaggta
    34741 accttgaacg cctccaacat atgtatcaga cgtggccttt tttccattcc ttgttatcaa
    34801 atgttgatat ggtattatct aaatcaaaca tgaatattgc ctttcagtat gcacaactag
    34861 ctgaaaggca ggatgttcga gatgtttttt atgagatttt ggatgagtgg caattgacaa
    34921 aaaatgttat tcttgctatc caagaccatg atgctctatt ggaggataat ccttccctta
    34981 agcatagctt gaaatcacgc ttgccgtatt ttaatgtgtt gaactatatt caaattgaat
    35041 tgattaaacg ttggcgtaat aatcaacttg acgaaaatga tgaaaaattg atccatacaa
    35101 ctatcaatgg catagcgact ggtttacgta attcaggcta atgctcttga gtattaattg
    35161 gtatttatag aagttttcaa gtgactaatc agaattttaa aggttagccc ttggagcttc
    35221 tttttttgag gattcttgac tttttctttt gtttgatata gaaagatgtt ataatgctaa
    35281 atgattatct caagaagtag agggaaaact atgaagattg ataaaaggca cctcttaaat
    35341 tattctatat tattgcctta tttaatttta tcggtgatag gcttaataat ggtttactca
    35401 accacaagtg tcagcttgat tcaagcacat gctaatccat ttaaatcggt gattaaccag
    35461 ggagtttttt ggataataag tctagtggct attacattta tctataaatt aaaattaaat
    35521 tttttaacga atacaagggt attaactgtg gttatgttag gagaggcctt tcttttaatc
    35581 attgcccgct tctttacaac tgctatcaaa ggagcgcatg gttggattgt gatcggacca
    35641 gtcagctttc agcctgctga gtatttaaag atcattatgg tatggtattt ggcattgacc
    35701 tttgctaaga tccaaaaaaa cattagcctt tatgattatc aagcactaac tcgtcgaaaa
    35761 tggtggccaa cacaatggaa cgatttacgg gactggcgtg tttattcttt gttgatggta
    35821 cttttggttg ctgctcagcc tgacttggga aatgcttcca ttattgtatt gacagccatt
    35881 attatgtttt ctatcagtgg cattggttac cgatggtttt cggctatcct agtcatgatt
    35941 accggtctat ccacggtctt tcttgggact attgccgtta ttggggtaga aagagttgct
    36001 aagattcctg tttttggcta tgtcgctaaa cgttttagtg ccttttttaa tccttttcat
    36061 gacttgaccg attcaggtca ccaattagcc aattcttact atgctatgag taatggtggg
    36121 tggtttggcc aagggttagg aaattccatt gaaaagcgtg gctatttgcc cgaagcacag
    36181 acagactttg tcttttcagt tgtcattgaa gagttaggtc taataggagc agggtttatt
    36241 ttggcacttg ttttcttctt aattttacgt attatgaatg ttggtattaa agcaaaaaat
    36301 ccttttaatg ccatgatggc tttaggagta ggcggtatga tgctcatgca agtctttgtt
    36361 aatattggtg gtatctcagg cttaattcca tctactggtg ttaccttccc ttttttgtct
    36421 caaggtggaa atagcttact tgtcttatct gttgcagtgg gttttgtact aaatattgat
    36481 gctagcgaaa agcgagatga tatatttaaa gaagctgaat tatcttatcg aaaggacact
    36541 cgaaaagaaa atagtaaagt tgtaaatatc aagcaatttc aataatattc taaaatctcc
    36601 tttaaggaga ttttagaata tagacaatcc cagtttgatg ctcaaaaaac ttgaactgct
    36661 ctgctgattt cttatttttg cgtgtgacat gagcccaaac agctgctttt tgctgtggca
    36721 aaaataaagc gtggaattcc aaaggaagtc gctgctataa gcaccaccta aggagagtat
    36781 caaaaaagac tttttcatct atttaaaaaa taaagaaatg gcaaaaaaca taaaatactt
    36841 gcattttcat tgtaatttgc tacaatagta aggtaaagtt agactgtatg gcctaccgtc
    36901 tatctataaa atatatttta ttggaggctt ttcctaaaat ggcaaaagaa aaatacgatc
    36961 gtagtaaacc ccacgttaac attggtacaa tcggacacgt tgaccatggt aaaactactt
    37021 taacagctgc aatcacaact gtattggcac gtcgcttgcc ttcatcagtt aaccaaccaa
    37081 aagattacgc ttctatcgat gctgctccag aagaacgcga acgcggaatc actatcaaca
    37141 ctgcacacgt tgagtacgaa actgcaactc gtcactatgc gcacatcgac gctccaggac
    37201 acgcggacta cgttaaaaac atgatcactg gtgccgctca aatggacgga gctatccttg
    37261 tagttgcttc aactgatgga ccaatgccac aaactcgtga gcacatcctt ctttcacgtc
    37321 aggttggtgt taaacacctt atcgtgttca tgaacaaagt tgaccttgtt gatgacgaag
    37381 agttgcttga attagttgag atggaaattc gtgaccttct ttcagaatac gatttcccag
    37441 gtgatgacct tccagttatc caaggttcag ctcttaaagc tcttgaaggc gacactaaat
    37501 ttgaagacat catcatggaa ttgatggata ctgttgattc atacattcca gaaccagaac
    37561 gcgacactga caaaccattg cttcttccag tcgaagacgt attctcaatt acaggtcgtg
    37621 gtacagttgc ttcaggacgt atcgaccgtg gtactgttcg tgtcaacgac gaaatcgaaa
    37681 tcgttggtat caaagaagaa actaaaaaag ctgttgttac tggtgttgaa atgttccgta
    37741 aacaacttga cgaaggtctt gcaggagaca acgtaggtat ccttcttcgt ggtgttcaac
    37801 gtgacgaaat cgaacgtggt caagttattg ctaaaccaag ttcaatcaac ccacacacta
    37861 aattcaaagg tgaagtatat atcctttcta aagacgaagg tggacgtcac actccattct
    37921 tcaacaacta ccgtccacaa ttctacttcc gtacaactga cgtaacaggt tcaatcgaac
    37981 ttccagcagg tacagaaatg gttatgcctg gtgataacgt gacaatcaac gttgagttga
    38041 tccacccaat cgccgtagaa caaggtacta ctttctcaat ccgtgaaggt ggacgtactg
    38101 ttggttcagg tatcgtttca gaaatcgaag cttaatttta attaagttcc cagaatagca
    38161 atttaagtca gacaacttaa gtttgaagaa gcccccaatt cgggggcttt ttgctatctt
    38221 aaactccata aaatgctgat aaataagaat gaaaagcttt cagaaaaagg gtttttattt
    38281 gtgaaaatat tcctaaaata taagcaattc cttttaatcg tcggtcattt gtgctaaaat
    38341 agaagatata aataaaaaaa gaagaggtat gtgatatgtc acgtaaacca attattgctg
    38401 gtaactggaa aatgaacaaa aaccctcaag aagcaaaagc attcgttgag gctgtagcaa
    38461 gcaaattacc ttcaactgac cttgttgatg ttgccgtagc agccccagct gttgatttgg
    38521 taaccactat tgaagctgct aaagattcag ttcttaaagt tgctgcacaa aactgctact
    38581 ttgaaaacac aggggcattc actggtgaaa catcaccaaa agtgcttgct gaaatgggag
    38641 ctgactatgt tgtgattggt cactcagaac gccgtgatta cttccatgaa acagatgaag
    38701 acattaataa aaaagccaaa gcaatctttg ctaacggttt aactccaatt gtttgttgtg
    38761 gtgagtctct tgaaacttat gaagctggta aagccgttga gtttgtaggt gcgcaagttt
    38821 cagcagcact tgcaggtctt tcagcagagc aagtagcttc acttgtttta gcttatgagc
    38881 caatctgggc tatcggtact ggtaaatcag ctactcaaga tgatgctcaa aacatgtgta
    38941 aagctgttcg tgatgtggta gcagcagact ttgggcaaga agttgctgat aaagttcgcg
    39001 ttcaatacgg tggttctgta aaacctgaaa acgttaaaga ttacatggct tgtccagatg
    39061 ttgacggtgc ccttgtaggt ggtgcatcac ttgaagctga tagcttcctt gctttgcttg
    39121 atttccttaa ctaagtcatc taaaaaagaa aaggttaaat ccttttcttt tttagatgac
    39181 ttaactctta ctataagaga ataaaggtga ttctacaggc aaatgcatta gcctaatagc
    39241 ggtttaatag cttttttgcc aatctaatga aatgatattt gattggaaat ggataacatc
    39301 taaatgtccc tggtttttgc aaaataaagc cattgaaatt ctgtttaaag cgcaagacac
    39361 cgtctgaacc atcaaacttt ccagtaatac caagaaaatt atattgtttg atgcccttgt
    39421 gaattgcctt gagcatagca tgctcttgta atagagctgg gctataaaat ttattaaatt
    39481 tggggtaaga tcctgaaaag aggtagacgg cctcttgttc ggtatagata aaaagacttc
    39541 ccgcaaggaa cacatcttta gttccatact cttcaagaaa atggagagct tcagaaattc
    39601 ttacctgaaa ggtttcgaac tggctggata gttcttttaa tctattttgc tttttttcag
    39661 aatgaggatt tttgccaagg tctcctttaa ctttgttgat gctggttgct agttgtagtt
    39721 gtctttgttt aaggttatta aggtaatctt caaaattaag agtcgcaacc ataaattcac
    39781 aagagtctcc aaaactatca taaaagtcct gatagtaaga taatgatttg tcaaggtaat
    39841 ctctacgatc agaggttgct tcagtaattt ctttgaaatg gtgtaactca tctcgtttca
    39901 gttgacgtaa tttaatacca aaagtattag ctttttttat taaagctttt ccttttttgc
    39961 tgaaggaacg ggttaaacgt gaggaatcaa ttccttctaa ctttttaacg taatgccaaa
    40021 caggttcacc ctcaggatag cctgttttta aaccgtcatg tttatatcct aacgccgtta
    40081 aaaggctaat aaggtcagtg tttggacgag aaatagggat gccatcagta tcaaatgact
    40141 gataattgtc gtaaggtttt aaaatgagtt cgataacgtc tttttgtttg gcatagtctt
    40201 taagttgagt gtaaaaatgt tctaattctt cgggatgatt ggtattaggg cctgcattga
    40261 gttccatacg ccaacctcca gccacttttt ggctaaagac catagcagca acctttagtt
    40321 caccatcttt ttcaagtcca agaaattgtg gttttgcccc tcttttagcc atcaagctgg
    40381 ccatttctga ggtttggata aaggaatgat ggacgagact gtggcagtaa tggtcaaatt
    40441 gttcttgtga aatttcaatt agtgccatta gttgtgctcc ttaatttttt tcttaagtta
    40501 taggttaaga tggctaagct tgaaacaagg ccgacaggaa tgttgaattc acctgcaaat
    40561 tcttcgatag tggggttgag tctagctttg aaatgataga gtccaccatc ttgttgattt
    40621 tccacacctc ctaaattatg ccagcggcag cctcttttaa aagcttcttt agccgtttca
    40681 taccaggtta aaagaggagc ttgataattg cgataatcat cgtccattcc cgcataaaga
    40741 ttttcagaag tctcgccata aatcaaggtt agggtggcgg ctaatgggat gcgggtttgg
    40801 cctgtagcga gctgctcgct taaaatggtt aaatcttttt gtagccgtgc aatggttttt
    40861 tgattttctg ctactttgct aggtttactc ttatctgtta atcgtgcttg ttctgctaag
    40921 gccttgtcca actgttggat caagagtttt ttttgttcag gtaagtctaa actagccata
    40981 gtaatgtagg actgaccagc ataaatacct agtaattttt gataatagga tttgcctcga
    41041 aggataatgc cttttcgatt ctcggttttt ttcatcaagg ctgaaaagtc gtctagcaat
    41101 tcactgccac caatcgtgac attaacacct ttattggtag cggtacgaat ggattgcttg
    41161 gcttttttgg gcaggctgtc aaagtcaaaa tccttggcgt agatgttggc ttgtattctt
    41221 ggttgaatag tgtcttcgag ttcttttgtt ctgccagacc attcgacacc gagttttttt
    41281 agaaaagcaa taatagagag tgtcacatca ttttctttgc tctcttttcc ttctaaagtt
    41341 tgtttgatga ctaaacttgg atcaattttg ataaaaagcg ctcgtttgct ttttccgaaa
    41401 gttttgagcg ttttaatgac gaaatcaagg agttcaaaat tggcgtagtc catgattggc
    41461 ccacgtggga tataaatcat agtgaaacca agaggaagtt ttctgattaa acaagcagca
    41521 gcagcaactt gtaccccatt ttcataaaag ctgatgcgtt cgtgtttcca gttatctttg
    41581 acttttcccc actttgaact ttgaagtaag ccagcttgtg gctgtgctaa gacaaactga
    41641 tcatgttctt caggagatat tccgatttta tatgtataca ttagtttaat acccacttgc
    41701 gaatagcatg tgccacacca ctgtcattgt tggatttggt gatgtatttg gctatttttt
    41761 tcaattcagg aaccccattt tccatgacaa cagggttggc aacgacttct aacatagcac
    41821 gatcattttc agcatccccg atggccatgg tttgtgacat atctagcccg agttttttag
    41881 ctaagtgttt gatggcatta cccttgctga cggtttttgg catgaactct aaataaaaag
    41941 gggttgactt gacgatggtg tacttatcaa agaaatgttg aggaatttgc ttgatggccg
    42001 cgtccaaaag gtcaggttca tcaatcatca tcattttgat gatttcttta ttggtcattt
    42061 cttcgggagt gcgatagaaa ataggcatgt ttaccaaagt cgattcatga actgtgtatt
    42121 ttccaatatt ccgattggca gtgtaaatac cttctttggt aatggcatgc atgtgaactc
    42181 ctaattttcg gctcaaaaat tccgtttcca gataatcgtc gtaagtcatc aattctttaa
    42241 caatttcttc gccggtctcg gcatcttgca ccaagccacc attaaaagtg ataacgtggt
    42301 ttcctttgtg gttgagttct aattgttcga gtaatgaaat cactccggca ataggtctgc
    42361 cagtagcaat caccacatga accccttggg ctttagcctc ttggacagct tgaaaaacat
    42421 catctgtaat tcgacggtca tcagtgagta atgtgccatc aatatcgaca gcaaccagtt
    42481 tgatagacat ggcatcctcc ttgttttttt gtggtttatc ttaaaaatgt tctccctcct
    42541 atcttactaa aaataggtgc ttttgtcatg ggatgggaaa ggaaacttaa ggaaaaacga
    42601 gagaaaacgt tttagtttag ctcaatcgcc tctgtagtaa ctaaaaagat tgaagaaagt
    42661 actctttctt caatcttaga atggagacaa acccagtttg atgctcaaaa agcatgaact
    42721 gctctgctga tttgacaact gatttcttat ttctgcgtgt gacgtgagcc aaaacagctg
    42781 ctttttgctg tggcaaaagt ggtgtcaata ctggcagtga cgttacgcgg aatttttgag
    42841 accctaggct caaaaataaa gcatagaatt ccaaaggaag tcgctgccat aagcatcacc
    42901 taagaaaagt atcaaaaaag actttttctg caatcttaaa gggctttact gactaaagtg
    42961 aaaatgccca ttggaaatat aactcataaa agtttccttg ctaggagcaa agaggtcatc
    43021 gagctctaac atttcctttg gaaaataaaa gcgacggtct ccgtaggttg tccctgttaa
    43081 tgctttgaca ataggagata actgagataa ttcagcaagg ctcccgtctt tttgcatcat
    43141 ttcaatctga gttcttggat tttcgagctc tggtcgataa atatcataag gcaggtcgaa
    43201 gttgatatgg ataccggtgt aataatctgg atcaaagcca actgattcga ccaattggcg
    43261 caagcgttct aactctcctt gggaatcttg gtcaaaggta acagacttca gaatttttcg
    43321 attaataaag cgactggcca aatctgataa gatatggtct tcgcttgcca tccagacttg
    43381 gaagtaagta ttcatgactc cgtcatctag ggctatataa tctgctaaat tagccttctt
    43441 ttcaaagaag gggatgagtc caggagctgt tttttggaaa taagcctgtt gctcaggata
    43501 taagtgttgg gctcttttga ggagattttg taagatgagc tcaacagcac ggctggcggg
    43561 atgaaaatag acctgcatgt acatttgaaa acgactgaca atatagtcct cgacagcatg
    43621 cataccacta tgttcaaaga caatgccatc ttcaacaggt cgaatcacac gtaggatgcg
    43681 cattaaatca aactgaccgt aattggcagc agaaaaataa gaatctctta aaaggtaatc
    43741 catacggtcg cagtcaatct ggctggaaat cagttgcaca acttgcttgt taggataagt
    43801 atgattaatc acgctggcaa ctttgtctgg aaaatcagga gcatgacgca ccaaaatggc
    43861 attgatttct gtctcaggat tggtaattat ctcctgagta aaggcctcgt gatccgtatg
    43921 aaaaagaacc tcaaaggtat gagaataggc tccatgacca atgtcatgta agagggcagc
    43981 cgtcatagtg accagacttt catctttatt ccagatatca gcgtatttct cttcaaaaat
    44041 agctgtcacc cgacgggcaa tttcgtaaac acctaggcag tgagaaaaac ggctatgttc
    44101 tgcgccgtgg aaggtgaaag ctgttgtagg gacttgtttg atgcgtcgta agcgttggaa
    44161 ttctttggta ttgataaggt cataaattaa tggattatca atgtggatat agttgtgaac
    44221 agggtcacga aatacttttt cattcataat ttttattata tcaaaaattg ataaaataag
    44281 gagaaattga tagaataaac agacgagctt agaatagaaa gaagagttat gaaattacag
    44341 ttaaccaacc atattcgctt tggagatgag acagagatta ttcaagaaat tcatgattgt
    44401 gagtggcgag aaaaaggggg ctatcagtac ctcatctatc aaaacactga caaggaaaag
    44461 gttgtcatca agtacaatga gacagaactg accatgagcc gtttttccaa ccctcagtca
    44521 atcatgaaat tttttgcggg caagaaggtc ctgattgctc tacctacgcc gatgggggtt
    44581 caacaatttt tgacagatac cagtcattac cacttagatt gttcttgtca aaaattggac
    44641 cttcattatc atttgcttca agctcaaaca gaaatgctat ttgcaagcta tcatcttgag
    44701 ctgagttggg attaactaaa aagatagcag taaatcatct gattagggat tattcttgtt
    44761 ttttagtcag gtttttacta taatggttat tatatcaagg gagtagcaga cggctagccg
    44821 tgattgtatc gtcaatacgg aatttcggtt tccggtacaa tcttaaacag cgagacttgt
    44881 ttaagaaaaa taaacaggtc tttttatttg aacaactaaa ataaaaagac caaggaggta
    44941 ctaatttgtc taaagaacaa agacatgaag cattttacac gcaaagtgaa gagaccgtac
    45001 tggctcaatt agagaccagt cgcgaaggtc ttacgtctgc ccaagcaaaa gagcgcttag
    45061 cagagtatgg tcgtaatgag cttgatgaag gcgaaaaacg aagtttattt atgaaattcc
    45121 ttgatcaatt taaggatttg atgattatta ttttgattgt ggcagccctt ctttcagttc
    45181 ttacagaggg gatggaaggt ttgacagacg ccattattat cttggctgtt gttatcctaa
    45241 atgctgcttt tggtgtttac caagaaggac aagctgaagc tgctattgaa gccttgaaat
    45301 caatgtcaag tccactggct cgtattcgcc gcgatgggca tgtgactgag atagactcta
    45361 aagaattggt ccctggagat attgtcttgc tagaagcggg agatgttgtc cctgctgatc
    45421 tgcgtctttt ggaagctaac tccttaaaaa tcgaagaagc agcgcttact ggagaatctg
    45481 taccggttga aaaagacttg tcaacggctg tttcagaaga tgccggtatt ggtgatcgcg
    45541 tcaatatggg atatcaaaac tcaaatgtga catatggtcg tgggattggg gttatcacta
    45601 acactggcat gtacaccgag gttgggcata ttgctggtat gcttgctaat gctgatgaga
    45661 cagatacacc attgaagcaa aaccttgaca acctttctaa gattttgact tatgcgatcc
    45721 ttgtgattgc agcggtgact tttgctgttg gagtcttctt gcgtggtcaa cacccgcttg
    45781 aaggcttgat gacttcagta gcgcttgctg ttgcagctat tccagaggga cttcctgcga
    45841 ttgttactgt tgtgctttct cttggaactc aagtacttgc taaacgtaac gccattatcc
    45901 gtaaattacc agctgttgaa acgctaggat caactgaaat cattgcttct gataaaacgg
    45961 gtaccttgac aatgaatcaa atgaccgttg aaaaagttta taccaacggg acactccaaa
    46021 gttcatcagc tgatattgct tttgacaata cgacacttcg tgtaatgaac tttgctaatg
    46081 atactaaagt tgatccttca gggaagttaa ttggtgaccc aacagaaaca gctttggtag
    46141 agtttgggtt agaccacaat tttgacgtac gtgaggctat ggtggcagaa cctcgtgtgg
    46201 cagaactgcc atttgattct gaccgtaagt tgatgtcaac cattcataaa caagctgatg
    46261 gcaaatattt catcgctgtt aaaggtgcac cagatcagtt attgaaacgt gtcacacaga
    46321 ttgaagaaaa tggacaaatt cgtcctatta cggatgctga taaaaaaacc attcttgata
    46381 ccaataagag tcttgccaaa caagctcttc gtgtcttgat gatggcttac aaatattctg
    46441 atgcccttcc aacactggaa acagaaattg ttgaggctaa tcttgtcttc tctggtttgg
    46501 tagggatgat tgaccctgaa cgtcctgaag cagcacaggc tgttaaagta gctaaggaag
    46561 ctggcattcg tccaatcatg attactggtg accaccaaga tacagcaaaa gctattgcga
    46621 aacgtcttgg tattatcgaa gaagatggcg ttgatcatgt ctttacaggt gctgaactca
    46681 acgaattatc agatgaagag ttccaaaaag tctttaaaca atactccgtg tatgcccgtg
    46741 tatctcctga gcataaagtt cgtatcgtta aggcttggca aaatgaaggc aaagttgttg
    46801 ccatgactgg cgatggggtt aacgatgcac catctcttaa aacggcagat attggtattg
    46861 gtatgggaat tacaggtaca gaggtttcta agggagcttc tgacatggtt cttgccgatg
    46921 ataactttgc aaccattatc gttgcggttg aagaaggacg taaggtcttc tcaaacattc
    46981 aaaaaacaat tcaatactta ctttctgcta acatggcaga agtctttacc atcttccttg
    47041 caaccttgtt tggttgggat gtgcttcaac cagttcactt gctttggatt aacttggtaa
    47101 ctgataccct accagctatt gctcttggtg ttgaacctgc tgagcctggt gtgatgaaac
    47161 acaaacctcg tggacgtaag tcaagcttct ttgatggtgg ggtgaaggaa gccattcttt
    47221 accaaggtgc cttccaaacc attttggtgc ttggggttta tggttttgcc ttgatgttcc
    47281 cagaacacac aagctatcat gatgtccatg cagatgcttt gaccatggct tatgtgaccc
    47341 tcggtttgat tcagttggta catgcctaca acgtgaaatc tgtttaccaa tccatcttta
    47401 ctgttggatt gttcaaaaac aaattgttca actattctat tccagtggcc tttgtagcat
    47461 taatggcaac agttgttgtt cctggattta atcaattctt tcatgtgaca cacttgacga
    47521 tcacacaatg gttagtggtt attatcggaa gtctcttgat ggttgttctt gttgaattgg
    47581 tgaaagctgt tcaacgatca cttggtcaag atgaaaaagc aatttaatag acgctaaaag
    47641 gtttgagaca attgtctcaa accttttttt ataatcgtta caatgataag gactattggt
    47701 atgcctgaca ttaaaaagtt gattcttgcc aattgacttg acagtcaaaa atttgttgtt
    47761 tggcttcttg actgtgacct tcaatatcat cgattaaaat cttagtagcc tgttcgcctt
    47821 cttcataggc gggttggata atagttgtta gtgttggtga agaaaatttt gtccactcaa
    47881 tgttatcaaa tcctactagt ccaatctctg gtatattaaa tttaagagac ttcatagctg
    47941 taaatacttt tggaagagcc caacaattgg ggacaaaaac caaactcttt ttagtcagtg
    48001 atccttgcaa aaactgagca attgcctctg aagaagtctg attttcatca ataatcattt
    48061 cttgatgagt aagatgatta gcttctaaca catcaatgaa gcctgaagcg cgttcaatac
    48121 gagtgctaag taaattgggg ttacccgtga tcatgataaa atgttcataa cctttatcga
    48181 tacattgttg aatggtatca taaacagcat cataattatt agttttgacc cagtttgtgc
    48241 gatgttcgta aagttggcta tcaaaaaaga caaccttctt ttttttaata tcgataatac
    48301 gtgaatattt tctaaagtta gaagttggtt gaataataaa accatcaaca ccaagattga
    48361 gcatcttttc aatgagttca tcttcgcgag aagggtcgta gttgctgttt ccgatgataa
    48421 tttggtaacc aaattcctgg gctttgcttt caattccttt gacaatttgg tttgaaaaac
    48481 tgtttgtgat gtcacctata acaacaccaa tgagtttagt cgattttgca ttgagacttc
    48541 tagcagcaat gctcggttta taattagtag ctttgatact ctcgctgatg cggtttttag
    48601 tttcttcaga catcttgtca aatctgccat ttaagtagaa agaaactgtt gtttttgaag
    48661 ttttcgctaa ttcagcaata tctttgatgg ttactttgcg ctgcattgca tacactcctt
    48721 taaaatagta atggttagtc atattataac ataaggactc gtaaaagatt tagtgtttca
    48781 atcgaataat ctcattcgtg atatggttga taacaaccac ctttcctctg attttatgac
    48841 tatttaggag aactagtttt tctcctttaa ttaaatcctc ttggagaaca cagatactgt
    48901 agtcaaactg ctttcctttt aaatgccagg aaagggcagt ctcaattggg ttgcgtttgc
    48961 ctgtttgaag tggtgttaag ggagtaactt tggtatcgtc agggactaat agggtactgg
    49021 tgcaaccctt gtctttaaag ggttttcgtt tgatgagttt gtgactagtc aggtattggt
    49081 tgtatttttt tgacaaaatc gtttcttcga tagtgaaagg gcagtcactg attagtctga
    49141 ggtcactaag gtgatctgtc tttacgtcta agtgattatc aagaataaat tgactgacaa
    49201 gacagtggtt gccttgagcc tgtatcgtat caatgataag aaaaattcct ggtggtaaga
    49261 tgagaatttg tcggtcatgt tggtagttgt tcctatcaga gaattgcgtc tggtagctac
    49321 cttcaataaa gtaaacgtgt ccattttgtc gaaggtgaca ataattggat ttggggtaag
    49381 aaaggtaagc ccaggagcta tcaatctgct caggtaattg ttcttctaag aaggcggtag
    49441 aatgatggct agcgcttttt agggcatagc gtaatggttc ttctttgtaa gtgtatcgcc
    49501 cagcatcaca gaaaagtggt tgtcctttat aatagagaca gagactattt tggtcgctat
    49561 gggtatggga actaccgatg ggcccatttt tgaaaaaaag ataataattt tcttgattga
    49621 tggtaatgtg cccggaatgt tcaaagtgat gcgcaaaagt tggtaaggtt tggacgggta
    49681 actgttcaaa agtgtggaca cctttttctc ctagaaggag aagactatcg atatcaagtg
    49741 tgggaaaagc agcagctttt aagtgtggtt cttcaaggat agtggctgca agcgttagaa
    49801 tatctctggt atctgtaaca tcgctatcac caagagggat ttgtttatga tctggaccag
    49861 tcattttgag gagataatca ctcatggcaa gcaaagtagg tctaagctgt ggaagataat
    49921 cagggactag agcagttaat tccagaaggg ctttgagtac ttccacatga tacatggttg
    49981 attgttcaaa ttgactgccg tcttcgagaa tttgtagtgc gatttgttgc gtcaattctt
    50041 ttctagcgaa agctgttgct gcagcaatat caaggtcaga accaaagtag gcatcagcta
    50101 ataaaatcgc agtggtttgc aagattcccc aattgctgag gctgtattta tcaaggtagt
    50161 tggcatggag aaattgaagt tgtttttcca gggaagctag gatgaggctt tcctcttgct
    50221 tggttaaggc gttaaaaaga ttaaggtaaa tcaaacattt gacccaagca aaacaacgga
    50281 tgccagtatc taaggttcta gtagctaacc ccttagggtc taaaggaata gctgattcaa
    50341 tccaattgag gatgaaacct ttagctgtta agagataccg ttcatctctt tcaacaaggt
    50401 agacgaggat taatttttgg agataggtct gtcgatttaa cataaagttc cactcaggat
    50461 catctatgac agcctcttgc caagtaatgg gatctaagtg gtaagggatg tggcagggct
    50521 ccatatccca attatcttca aataaaaagg tattggttaa gagtaggtca gctattcttt
    50581 tttgatcagc atagctgtca gtctgatagt ctagcaggta attcctgcaa aagtctggat
    50641 tgactgtttc tttaaagcgt gcgaaggcaa aaaacatagg acatttcctt tccaaaagaa
    50701 aagagacctc atcatgtgct taggaactat ttccctatgc tcataacagg tctctatgaa
    50761 ccattaagct aaaataccca accaactgcc aataacacca atgataacag ttaaaatgac
    50821 caatttgtag gttgtccatt ttttgttttt aataaggtaa tacatgagta aggtaaagag
    50881 agctggtaaa agtgcagggg caatcttatc aagcattcct tgaatagtca caaatttttg
    50941 tgctgtattg gccgcatcca ccttgccagc ggcaaaagta atgggaacag taattttaac
    51001 agaagtagct gctagtccag cgataacggt aacgccgaca atatttgcca tgcgcgacac
    51061 aaccgccatt tgttcactta atttatcaat aaagcttgtg ccgaccttgt agccatagag
    51121 tccagaacca attttaatag cggttaggat aatattcatg gctaggaaga agaggattgg
    51181 tcccaaaacc agaccatcac tagctaagga agctgcaatc gttgaaaaga gtggcgccaa
    51241 gcaaaattgt gataaggagt caccgatacc agctaaaggc cccataagtg ccattttgat
    51301 gtttcgggtt tcttcttcag ggcgattatt ttctaacatg accaagtgca gactggtgat
    51361 gaaaggaagg aagtgaggat tagtattgta aaactcacag ttatcttcta aagcttgata
    51421 taagcccttt ttatcactgc caaaatgttt tttcaaggca ggatagatga cattggcgta
    51481 tccgatacct tggtaattat tgtaattaaa cccattttgt aggaagaaag ctctcagagc
    51541 tgttttgagg taatctttct tggttaattt attagatcca gtcatcttgt tggcctcctt
    51601 ggacagttgt tgcatcgact tgtttaggtt tgttgtaaaa ttcattcaag gcgaaaatga
    51661 taccaataat ggcgatacca atggttggaa tttggaggta ggctgcacaa acataaccaa
    51721 ttagtacaaa aggaatcaat tctttcttgg ccataacaga taagatcatg gcaaatccga
    51781 tagcaggtaa cattttacca gcgacagtca atccattgag caagacaggt gggatataat
    51841 caaccaagtg aaggagagta tccattgaca aggcacctaa taaaccaagg cctaatccga
    51901 taaaagcgaa agcccagata gtgccgttgg cagcgaattt gaagcctcta atattgcctt
    51961 tttgcaattg ttttttagcg gtttcgggag cgccagcaaa agctgtatag gcgaatgttt
    52021 gaaggaattg gatggcaact gcgattggtg ttgataaggc tagtgccgct tctggggtga
    52081 ctttaccagc actggtaata gccatcaagg taccaaagat accagggccg ataggattag
    52141 gaggaacggt accaccggca cccactccaa atcccatata agctaattcg gagatagctc
    52201 ccatgctaag tgcagttggc aagtcaccta agataatccc tacaccaaaa gacagaataa
    52261 tacaacggtt ggtgtagatg ccaagtaaca ttccgctgaa acaaaaggct gtccaaagac
    52321 caattaaaag tgcctgtaac aaattgatat ccatatcaat ctcctttatt cattaaatat
    52381 aatctaagat gtcaacgtca gaggcgctat tgccagctgg agttgttttg gtgttaaaaa
    52441 ccacgtggtg gtcatgggct aagcaacgaa tagcagactt gtctgtttct cccagcgaaa
    52501 taaactgggt aatcgcaacc ttatcatcag ttttatgaat attaccgata ttgatttctg
    52561 tgatgggaac acccccttca actaggagtt tggcatcttg caaatctttg accacgatga
    52621 agatactttg agcaggactt gctttatgaa tgatgtcaat cactttttga atggagaaaa
    52681 aacgaatggc aatactggat ggaataactg ttttcatgag ggattgttga atcttatctt
    52741 cagaaaccgc atcgttagcg acgataacgg tgttgcagtt gaggaatttg acccataatt
    52801 gcccctgtcc gtgaatcaaa cgctcatcaa ctcgcgtcat gataatgttt ggttgtgtca
    52861 taaaatctcc tttttaaatg taggtatcgg tgtttgttac cagtaagggt tccagtcttt
    52921 gtagaaacga agcagagctt caagatagta atagtctccc cagatatttc cctcgtcaac
    52981 cccttttcca gagtgccaag aatagactcc gtgaagcagt agaggagcac caggcttgag
    53041 atctttgtta gcataatcct taatcaaggc tcttagcatg ctgtgcatgg cagcttcata
    53101 tgttttttta tcaggatcat gatctggtaa ggtttttaac atttcatgaa taccacacac
    53161 agcaatggcg gttgctgaac tatcacgaga ctgctcgcta ccatctccaa aaattaaatc
    53221 ccagtaggac acctggtctt taggaagacg gttcaagaaa taatgggtca tgcccttgaa
    53281 gagttgaatg agttcaggtt cttttaggaa acgataggtc aaaggaatac cataaatgcc
    53341 ccaagcttgc cctctggccc aagcagaatc atcgctataa ccttgtcggg tgaccccttt
    53401 aacaggatca cctgtttctg gatcaaagta gaaggtgtgg taagcagagg cgtcatctcg
    53461 gatgacatga ttggctgagg cgtagaaatg attgatcgcc atgtcacggt aacggttgtc
    53521 tccagtttct tggctagcaa aaaagagtaa ttggatgttt aggagacaat caatgattaa
    53581 acggtaatct tcttttttac ccagttctcc ccaggcctga ataaagccgc ctttgtcttg
    53641 atagcgttgg actaatttgt cggctgcttt caaagcagct tctctagact caggtgtttt
    53701 taaaagtttc cactcagcca tgcaagaagg ggtgtaaaga aagcccaaat catggtgatc
    53761 tagctcaatg tctcttgtta ctcgatctag gaaagaaagg tcatttgctt gagccagagc
    53821 tttaatagca tcatccccac tgtattcgta agctaaccaa aggcaacctg tccaaaaggc
    53881 attggtccat tctgtattat ccataatggc atattggtta tctttggtag ctggcgttgg
    53941 aaagtcttct ttaaaatagt ccatattaag ccgaacttgt ttgagggcta agtcaagggc
    54001 ctgagtaatg tcttcttggc ttaggaaatc ttctttggta aatcgttcag gctgcttgat
    54061 aggttcaaga gcaatggttt ttaaaggtcg tgccattaaa tgcctcctaa ctcatcgtct
    54121 gtcgcaccgt cttcttgctg agaaagagtt ttccagtcaa caatgccttc tttagaacat
    54181 gttataagtc ctgatactaa gtcgtcaaaa gaagctgctg tttgtcttgc aaaactagct
    54241 tcaatcagca tggctaagtt aaggccagaa agaacattac acgtcgtgtt tggaagagat
    54301 tccattaagg ttgcagcgac tttaaaaggg gtacctccta gaaggtcaca aagaactaag
    54361 gtttcctctt ctgggattaa agcacgagat aattggtcct gcacatcagc ggcggtcatc
    54421 tcagtagtaa aatcaattgc agttaccttt tcttgtttgc ctgcgatcaa ttctaaggct
    54481 gaaacaatac cactcgcaaa atgtccatgt cccataacga taatagcaat cataaataaa
    54541 tctccttcgg tttaccggtt tactcaaaaa tattgtagcg ctttcaaaat tctttgtcaa
    54601 tactttttta aaaagatttt tgaaaaagaa aaagtgaacg gttgtgctaa aaaagaatca
    54661 aaaatggtct ttttttgtca ctatttaatg tagaaaagtc ttaatggcta ttaagtatag
    54721 gagaagacta aacaagaatg gcagtttgga taagagcact cttttaaatt ttgaaccgtt
    54781 ttcattaaaa tgattgacaa aactagttta ctttgttata gtcttggtaa acaggtttac
    54841 ttaatttaat aacaaaaagg agaatcctat ggaaaatatg ttttcgttac aaggtaagat
    54901 tgccttgatt accggagcat cttacggtat tggttttgaa attgccaaag cctatgctca
    54961 agcgggtgca actattgtgt ttaatgacat caaacaagag ttagttgata aggggttggc
    55021 tgcctatcga gagttaggga tagaagcgca tggctatgtt tgtgacgtga ctgatgaagc
    55081 tggtatccaa cagatggtta gtcaaattga agatgaagta ggtgctattg atattttggt
    55141 caacaatgca ggtattatta ggcgtacgcc gatgcttgaa atggccgcag aagattttcg
    55201 tcaagttatt gatattgatt taaatgctcc ttttattgtg tcaaaagctg tattaccatc
    55261 aatgattgca aagggacatg gtaaaattat aaatatctgt tctatgatga gcgaattggg
    55321 gcgtgaaaca gttagtgcct acgcggcggc taaaggtggc ttgaaaatgt taaccaaaaa
    55381 tatagcctct gagtttggag aagccaacat tcaatgtaat gggattggtc ctggctacat
    55441 tgcgacgccc caaacagctc cgttgagaga gcgacaagca gatggtagtc gtcatccttt
    55501 tgatcaattt atcattgcta aaacaccagc agcacgttgg gggacaacag aagacttagc
    55561 tggtccagct gtttttctag ctagcgatgc cagtaatttt gtcaacggcc atattcttta
    55621 tgtcgacggt ggcattttag cttatattgg aaaacaacct taatcacaca ctagaaagag
    55681 attttatatg aaaattgcat taattaatga aaatagccaa gcggctaaaa atggtatcat
    55741 ttacgatgcc cttaccacag tgacagataa acacggctac caagtcttta actatggtat
    55801 gtatggcaca gaaggtgaaa gccagttgac ctatgttcaa aatggactct tagcttctat
    55861 tttattgacc actaaggcgg ctgattttgt ggtgactggt tgtgggacag gtgttggagc
    55921 tatgttggcc ttgaacagct tcccaggtgt tacctgtggt tttgcgagtg agccaacaga
    55981 agcttatctc ttttctcaaa tcaatggtgg taatgccttg tccattcctt ttgccaaagg
    56041 ttttggttgg ggagcagagt tgaatttgac cttaatattt gaacgcctct ttgcagaacc
    56101 aatgggtggt ggttacccta aagagcgagc tattcctgaa cagcggaatg cacgtatttt
    56161 aagtgatctg aaaaaaatta cttacagaga tttgttggca attgtcaaag acatcgacca
    56221 agatttcctc aaagaaacga tttctggcgc tcatttccaa gagtacttct ttgccaatgc
    56281 ggagccgtca gaattagtca cttatttgaa atcagtactt gaacagtaat tccattttga
    56341 cgaggaaagg aggtcacatg tctaagttat tattggttgg tgaaccgctg attcgcgtta
    56401 gccccaatca gtttcagcct ttgaccaatg cctgcgaggc tcagcttttt ttcggcggtt
    56461 cagaagttaa tattgcaaga actctaggcg gttttggctt agaagcaagg ctatttacgg
    56521 ccctaccaga taatcctgtt ggtcacgctt ttcatcagtt tttgaagcaa agcggcgtgg
    56581 atatgtcctt gacggcttgg caaggtcatc gcgttgggct atattacctt gaaaatggct
    56641 ttggctgtcg ggctagtcag gtttattatg accgctgtgg ctctagcttt tcggccttag
    56701 ataaggatag tcttgattta gctgccattt ttgaaggcat tagtcacttt cattttagtg
    56761 ggatcagttt ggcgttgggc aaaaaaactc aggacctgat tgaggtactt gtgagagaag
    56821 ctaagaaaag ggatatttgt atttcctttg accttaactt tagatctagt atgattgccg
    56881 tagctgatgc taaacgactc ttttctcact ttgctcaata cgcggatatt atttttggca
    56941 tggaaccttt gctgttagac agtgacgatt ttgacatgtt tgatagaaaa aaggcagata
    57001 ctacgacgat tagagaacgt ctggcaggac tttatcagcg ctatcagtta caagctattt
    57061 accatacgga gcgttcaaat gatgcccaag gcagtaatca tttcaaagct tatgcctatg
    57121 ataggcagtt ttacgaatcc tgtgaagtga cgaccccagt cttgcaacgg gttggaagtg
    57181 gagatgcttt tgtggcgggt ttactttatc agttgttaga aggtaacgaa aagcagcgca
    57241 accttgattt tgctgtggca acagctagcc taaaatgtac agtagctgaa gatcagctct
    57301 atcacagtgt ccaacaagta gaagcagtct tagctaatca acgagatatc cagaggtgat
    57361 gatatgggaa aaatagaaat cttaaccaaa cttaaggcta atcggcttgt cctagttgta
    57421 cgaggagagt ctagtgagga agctttagct tgcagcctgg ccagtattga aggtggcatt
    57481 aagacaattg aagtcaccta tactaacccc tttgctagtg aggttatcgg tcaattagct
    57541 gaacgcttca aagaagatcc tgaggtattg ataggtgctg ggacagtttt ggatgatgtc
    57601 actgcccgcc aagctatttt agcaggagca cagtttattg ttggtcctaa tttcaatcga
    57661 gcagtggctt tgatttgtca tcgttatagc ataccttatt taccaggttg tatgacggtt
    57721 aatgaagtgg ttacagcatt agaatcaggg gttgatatgg tcaaaatttt tcctggttct
    57781 actgtaggga tatcctttat tcgggcaatc aaatctcctt tgccacaagt agaggttatg
    57841 gttacaggcg gagtttcttc agataatctc aaagactggc tagctgctgg agtagatgtt
    57901 ctaggcatag gaggcgagtt taatcagtta gcgagccaaa aacaatataa cctaatcact
    57961 aagaaagccg ctcattatat caaaagtttg cgacaataat ctaaaaaacg tttttacctt
    58021 ggctttagtg ctagtaaaaa cgttttttta tcattcattc aattaatatg cttctgctca
    58081 tgtttttcca gatagtatag atataagagc agctaattta acaagatgag cctgtcgttt
    58141 gatatatagg atataaactt tttatgatca aacaaaagta ataccttttg aattcgttag
    58201 tattgatctg atctaaagtg atatcactta gaatggacta gctgtacagc ttttacagca
    58261 acttatgcta aaatagaaaa aaggagaaat gttgatgatt aaaggaatta tttttgatat
    58321 ggacggtgtt ttatttgata cagaaccttt ttatctgagg cgacgagaag atttttttaa
    58381 gacaaaggga attcccattg atcatttgaa ctctaaagat tttattgggg gcaatcttca
    58441 agaattatgg aaagagttgt taggtaaaaa tagggatgat gctatcgtta aggcaattac
    58501 aactgactat gacgcttaca aacaagcgca taagcctcct tatcaaaaac tgttgattac
    58561 agaagtgaac tcttgtcttg aacagttgga aaaacaaggt attaaactgg ctgtggcatc
    58621 aaactcgaag cgtcaggatg ttttgttggc gttggagaca acgcaaataa aagattattt
    58681 tgaaataatc ctagcgcgtg aagatgtttc tagaggcaaa ccttatccag atatttataa
    58741 taaagcagta caaaaactag gattacaaaa aaaacaactg cttgtagtag aggacagcca
    58801 aaaaggcatt gctgccgcca aagcagccaa tctgacagtt tttgccatta ccgactaccg
    58861 atatggcatt gatcagagtc aagctgatca caagatagat catttaggac aactgtgtgt
    58921 aaaaatcggt tgttttggat cgtgaagtaa cgcaactaac tgatcatgat acttcaagac
    58981 agttaagaat acgtctagga ctttctacag accaataaca agaatatgtt tatgtgtttt
    59041 tactgttttt tagctaccta tttacaatat gacactgaaa agagtactat gtttaagtta
    59101 ttatcaaaaa aaacgtcgca taagatcacc tagaaaagga ttatgatttt tgtgatttgg
    59161 atgcgatcat tagtcgtcga ccatcttcat ttggcaggag gtatgtttaa ccgtggtcat
    59221 tatttggatt tgtttttaga ttggctagtg agtaaatata gaaggatcat aatactgctt
    59281 tgacaaaggc agtatctgag tccatgagtt gcacgggtaa tgtgactcgg ttttggttag
    59341 gtataataat atttggaagt gttatgctgc ttgtcttcgt aggtccattg attatagtca
    59401 gacttacttt agagctgagc tgactgtcta gacaagacgt gatggagatg tgatttctga
    59461 ccaagtagag gtaaccagaa aagggacttt tacgatggaa ttgaatttac ttgttgcatt
    59521 cttgtgcatg ttaagagaga aaacccagat aaatcaggaa gtaaaatggt tatgtttgat
    59581 tagaattgtc cttctttttc cttgaagtct taacttattt tgattatgat agtagtatga
    59641 ctattaaggc agaaattaag gcgctcgcca aagaaattgg tatctctaaa attggtttta
    59701 cgacggcaga taactttgat tatttggaaa agtcattgcg tgcttctgtg gaagaggggc
    59761 gcaattcagg atttgaacat aaagtcatag aggatcgtat ctacactgaa aggcttttag
    59821 aatcggctaa aacgattatt tcaattggcg ttgcttatcc tcacaaactt cctcagcaac
    59881 ctcaaaaaac accttataaa cgtggaaaaa ttacacctag ttcgtggggg cttgattatc
    59941 attatgtggt cggcgaaaag ttagacagac tatcaaaagg cattgaagag ctgtgtcgag
    60001 attttccttt gcaacaaaaa gcaatggtcg atactggagc tttagttgat actgcagttg
    60061 cccaaagagc gggtattggt tttataggaa aaaatggtct agttatttct aaagaatatg
    60121 gctcttatat gtttttggga gaattaatta ccaatttaga gatcgagcca gacaagcctg
    60181 tcgattatga ttgtggtgac tgtcgtcgtt gtctagatgc ctgtccaact tcttgtttaa
    60241 ttggtgatgg ctcaatgaat gccaagcgtt gtctatcatt tcaaacccaa gataagggaa
    60301 tgatggacat agagtttcga aaaaagatta aaacagttat ctatggttgt gatatttgcc
    60361 aaatttgctg tccttataac aagggtataa acaattcacc agctacagag attgatcctg
    60421 agttggctca accagaatta ataccatttt tgagtttatc aaatggaaaa tttaaagaaa
    60481 aatttggtat gattgctgga agttggcgag gtaaaaatat tttacagcgt aatgccatta
    60541 ttgcgctagc aaatgctcat gataaaactg cagtggtcaa attaatagag attattgata
    60601 aaaataataa ccctattcat actgcaacag ctatatgggc attgggagaa attgtcaaaa
    60661 aaccaaacga tgagatactg gcgtttatga gtcatttaac cttaaaagat gaagatagcc
    60721 gaaaagagtt ggaattaatc cgtcataaat ggcaatttta agccttttat ggtattttta
    60781 agaaccttat gataaaataa aacagattaa caaagattgg agaaatctca tggaagtggc
    60841 tgaaattcgc caaaaaatag tagaaaataa agagaagttg actagcttca ggaggtctct
    60901 ttgacttaga tcgtttggaa gaggagattg ctcttcttga aaatcacatg actgagccag
    60961 acttttggaa tgacaatatt gcagcgcaaa agacatctca agaactaaat gagttaaaag
    61021 gtaagtatga tactttccat aatatgcaag aattatctga cgaaacagaa ctcttacttg
    61081 agatgcttga cgaagatgat tctttgaaag aagaattaga agaaaatcta atgcagctag
    61141 ataagataat gggtgcttat gaaatgacgc ttctcttatc tgaaccctat gaccacaata
    61201 atgctatctt agaaatccat cctggttcag gaggaactga agcgcaagat tggggagatt
    61261 tactcttacg aatgtatacc cgttttggca atgctaatgg tttcaaaata gaagtattgg
    61321 attatcaagc aggagatgaa gctggtatta aatcggttac cctctctttt gaaggcccca
    61381 atgcttatgg tttgttgaaa tcagaaatgg gagttcatcg cctcgttcgt atatcacctt
    61441 ttgattcggc taaacgtcgt catacctcat ttgcttcagt tgaagtgatg ccagagttag
    61501 atgatacgat tgaagtagaa gtacgtgatg atgacattaa aatggatact ttccgttccg
    61561 gaggagctgg tggtcagaat gtcaataaag tatcaacagg tgttcgtttg acgcatattc
    61621 caactggaat tgtggtatcg tctaccgttg accgtactca atatggaaac cgcgatcgcg
    61681 ctatgaagat gttgcaggct aagctatatc agttagaaca agaaaagaaa gcacaagaag
    61741 tagatgctct caagggtgat aaaaaagaaa tcacttgggg aagtcagatt cgttcttatg
    61801 ttttcacccc ttatacgatg gtgaaggatc atcgtactaa ctttgagctt gctcaggtag
    61861 ataaggttat ggatggagag atcaatggct ttattgatgc ctaccttaag tggcgcattg
    61921 aagactaaaa ataataaagg agaaacatgg cactaataga aatgtctggt gttactaaaa
    61981 aataccgccg ctcaacgacc gccctcagag acgtcaatgt ttctgttaac caaggtgagt
    62041 ttgtttatct cgtaggccca tcaggtgctg gtaaatcaac ttttatcaaa ctcctttacc
    62101 gtgaagaaca actgacaact ggtaagctat atgtgggtga attcaattta actaagctaa
    62161 aagcacgtga tgttccgatt cttcgtcgtc acatcggagt agtttttcaa gattacaaac
    62221 tgctaccaag aaaaacagtc tttgaaaatg tagcttacgc catggaagtt attggtgaaa
    62281 agcgccgcca cattaaaaaa cgcgtgccag aggtactcga tttagttggc ttgaaacata
    62341 agatgcgttc ttttccaagt cagctatcag gaggggagca gcaacgtgtg gccattgcgc
    62401 gtgcgattgt taacaaccct aaattattga ttgcagatga accgacaggg aatttagatc
    62461 ctgagatttc atgggaaatt atgcagttac ttgaacgtat taatgttcag ggaacaacta
    62521 tcttaatggc gacacacaac agtcatattg tgaatacatt ccgtcatcgt gttgttgcta
    62581 ttgaagatgg tcgcatagta cgtgatgaag aaaaaggaga ttatggttac gatgattaga
    62641 tactttttcc gtcatatttg ggaatccatt aaaaatctta aacgcaactt ttggatgaca
    62701 tttgcttcag ttagtatggt ggctgttaca ttgactttag ttggtgtttt tgcggcgaca
    62761 ttgttgaata tacagcgtgt tgcttcgggt gttgaaaata atgtccatat caatacctac
    62821 ttacaagttg attcaactga tgctgcaaaa gttattcaaa atactgccgg tgaacctgtt
    62881 aataacgata actaccacag tgtttacgac aaaattgctc agataaaagg tgtcaaaaag
    62941 attacatttt ctagcaagga tgaacaattg aaaaaattgc aagaaacctt aggtgatgtt
    63001 tggaatatgt atgaccaaga cactaatccg ctccaagata tctatcttat tgagacccag
    63061 acgcctaaac aagttaaggc gatcactaaa aagatcagaa cgattgaagg cgtagaagcc
    63121 gcagattatg gagggattaa ctccgataaa ctatttaagt tttcaacatt aattcaaact
    63181 tgggggctga tcggaacagc aatgctatta tttgtagctg tctttctcat ttcaaacact
    63241 attcgtatga ctattatgtc tcgtaaacgt gacattgaaa ttatgcggtt agttggtgct
    63301 aaaaattctt atattcgagg gcctttcttt tttgaagggg cttgggttgg cttgttagga
    63361 gctgttttac catctcttct gatttattat ggatatgatc ttgtttataa gcattttgca
    63421 caagaattac aacgtaataa tctctcgatg tatccgcttg atccttatgt atattacctg
    63481 attggtgctt tgtttgtcat aggtattatg attggttcgc ttggttcagt gctttctatg
    63541 agacgttatt taaaattcta aaaaaagcgc tgctgacgaa acgtagcgac cctcaaaagt
    63601 tggacctctt atgttattcc aaggacctcg ttttgtattg cacaggactg gtccttttca
    63661 ttttgttttg attcatttgt ttatttgtaa taggcaatac agtttaaaat agcagtttct
    63721 aaggtttcaa gagaagaaaa gcaccccaaa agttagatgt ttgatgtatc taacttttgg
    63781 ggtgtcattc aaaatttagt ggctcttttt tagtaaaata ctatgatttc agttttagga
    63841 taacctcaaa cagtatctaa aatagctatg tcaatgaaaa aaggggttag catttttttc
    63901 gtgacaaatg gtagtagaag gaccatgccc aggataaact cggtaatgat taggtaaggt
    63961 gaatagttct tggcgaatac cagtaatgag gtcctcaaag ttactggtag gtaagtcagt
    64021 acgaccgata gtttcacgaa atagagcatc gccagtaacg actaattcat ctgagtggaa
    64081 aacaaatgag actcctcccc aagaatgacc agatgttggt aaaactgtga attcaaaacc
    64141 atttagttga tagggttgct ttaatttaaa aaagttctct gccggtcttg ctataacagt
    64201 aatgatatca tcatgacggc ctaagccaga taaattatca tctggggaag atagccaagc
    64261 ggcttctttt tctgaaacat aaacaggtgg atgatcaaaa gcatctctga ccaaatctaa
    64321 actaaaaata tgatcatagt gagtatgcgt taagaggata gccactaaag gtttttcaaa
    64381 ggatttaatt ttagcaatga tttcttggcc gttacttcct ggatcaatga ggataacagc
    64441 ttgatcatta acgaggtaat aagtattttc accagcaatg tggtttattg ttttatagat
    64501 tttcataagg atagtgtacc aaaaaatcaa gactttgtta aaaaaagagt agcggaaaat
    64561 aaatggcaat tagtttcaga aaatatgaga tctcacagca atttcttgac accgttttca
    64621 taaaggtgta tcataaaagt aatcaataag ccaagcctaa agctgaactt agtttaagaa
    64681 cactgacttt ttgagagcaa cctaatcggt tgactaaaaa atatgaggtg gaagatatgt
    64741 caaaagttgc tattgttact ggtgctggtc aaggaattgg atttgctatt gcgaaacgtc
    64801 ttcatgcaga cggctttaaa ataggcattt tagactataa tgaagagact gctcaggctg
    64861 cggttgataa actatcacct gaggatgctg ttgcagttgt agcagatgtt tcaaaacgtg
    64921 accaagtttt tgatgctttc caaaaagttg tagatacttt tggtgatttg aatgttgttg
    64981 ttaacaatgc aggcgttgcc ccaacaaccc ctcttgacac gattactgaa gagcagtttg
    65041 aaaaggcttt tgcaatcaat gtcggaggaa cgatttgggg aagccaagca gctcaaaaac
    65101 attttagaga attaggtcat ggcggaaaaa ttataaatgc aacatcacaa gcaggatgtg
    65161 aaggaaatcc taatttgact gtttatggtg gtacaaaatt tgcagttcgt ggtattacac
    65221 agactttggc aaaggatttg gcatcagaag gaatcacagt caatgcttac gcaccaggta
    65281 ttgttaagac acctatgatg tttgctattg cccatgaagt tggtaaaaat gcaggcaaag
    65341 atgatgaatg aggtatggag caatttgcaa aagatatcac tttgaaacgc ttgtctgaac
    65401 cagaagatat tgctaatgca gtaggcttct tagcgggaga tgattcaaat tatatcactg
    65461 gacaaacaat agttgtcgat ggtggtatgg tattccatta aaaatgatta atactgacac
    65521 tgtgggtttc actcacagtg ttttttaaga agtataaaaa attatcctat cttggttatt
    65581 ggagtgatgg cacctttgag gtatagtcat gttttgtttt atagatatag cgtgctataa
    65641 tagacttact atgacccaga aaaaacttag aaaatatgca gtagttgact tggaggctac
    65701 tggagcaggt cccaatgctt ctattattca ggttgggatt gttattatcc aaggaaataa
    65761 aattattgat agttatgaaa cagatgttaa tcctcatgaa tctttggatg agcatattgt
    65821 tcatttgaca ggtattacgg ataagcagtt ggctaaagct ccggattttg gtcaagtggc
    65881 gcatcacatt tatcaattga ttgaagattg tatttttgtt gcccacaatg taaagttcga
    65941 tgcaaattta ttggcagaag ctcttttttt agaaggatat gagttaacaa taccacgtgt
    66001 tgatactgtt gaattagccc aactattttt ccctcgcttt gaaaagtata accttagtca
    66061 cctatctagg cagctcaata ttgatttggc agaagctcat actgctattg cagatgcaag
    66121 agctacagct atactgtttt taagactttt acaaaaaatt gagagccttc caattgagtg
    66181 cttagaaagc ttattagtct attcagatag cctgctattt gaaacagcaa tggtcattca
    66241 agaaggatta gccaaagcca aaccttatga tcccaacaaa tacattaaaa tcagacagat
    66301 tctcttacca aagggctcaa aagctctcaa gccttatcaa atatcaaaaa gcttccctat
    66361 taatatggca ctattaggtc tggaagaaag gcctaaacag actcaatttg ctcagttaat
    66421 tgacgaagat taccatcagg gagtagctag ttttattgaa gctcagacag gtattggaaa
    66481 aacctacggc tacctgctac cccttttggc aaaagaagat caaaaccaaa tcattgtcag
    66541 tgtgcccacc aaacttcttc aagaccaatt aatggctggt gaagtagctg ctattcaaga
    66601 acaatttcac atcgcctgcc atagtttaaa agggcccgcc aattacctaa agctagatag
    66661 ctttgcagat agtttggacc aaaatgacca gaaccgtttg gtgaatcgtt ataaaatgca
    66721 attattggtt tggctcttag aaactaagac aggagacctt gacgaaatca aacaaaagca
    66781 gcgctttgca gcttattttg agcagcttaa gcacgatgga gacattaagc agtcttctga
    66841 attttacgat tacgattttt ggagagttag ttatgaaaaa gccaaaacag cccgtctcct
    66901 gattaccaac catgcttatt ttttacaccg tgttcaagat gacaaggact ttgctagaaa
    66961 caaggtcttg gtctttgatg aggcccaaaa gctgatgctc caattagatc aattatcacg
    67021 tcatcagctt aacctgacgg tttttttaca aacaatacag gccaagttaa gcaacccttt
    67081 acctctttta gaaaaacgct tattggaaag cttgtcgttt gaactgggac aagtgtcaag
    67141 tgattactat caaaataaag agcaccagct tgctcatgat tggtctcgta tagctggcta
    67201 cgccaaagaa ttaacaggag cagattatca agagttacaa gccttttttg ctacctcaga
    67261 tggtgactac tggcttagta gcgaaaagca agaggagaag cgagtgactt atctaaacag
    67321 tgctagtaag gcatttattc atttccaaca gctcttacca gaaacggtga aaacttattt
    67381 tgtttctgcc actttaacca tcagctcaga agtaaccttg gcagacctat taggttttga
    67441 agagtatctc tatcatgtca ttgaaaagga taaaaagcaa gaccagttgg tgcttgttga
    67501 tcaagaggcg cctatcgtga cagaagtcag tgaccaaatc tatgtggaag caattgcaaa
    67561 acgaatcgaa agcttgaagc aagagggtta tcctatttta gtgcttttta attctaaaaa
    67621 acacttgctg ttggtttcag actatctaga ccaatggcag gtgcctcact tagcgcagga
    67681 aaagaatgga acagcttata atattaaaaa acggtttgat caaggagagc aaactatttt
    67741 gcttggttta ggttcttttt gggaaggagt tgattttatt caagcggatc gtatgattac
    67801 ccttatcgca cgattgccct ttgataaccc agaggatttc tttgttaaga aaatgagtca
    67861 ttatctattg gaaaaaggta aaaatccttt cagagattac ttcttgccaa tgactatttt
    67921 gcgattaaaa caggctattg gtcgcacgat gcgtcgacaa gatcaaaagt cagtggttat
    67981 tattttggat cgtcgtctcc ttacaaagtc ctatggacaa gttattttgg aaggtctcgg
    68041 tcaggaattt ttgatttctc aacaaaattt tcacgattgt ctagtagaaa cggactgttt
    68101 tctgatataa tggaaaggat ctattatatc agaaaaattt ttaatggcgt taagcacaat
    68161 caactaacat ttaaattagt ttgaactttt attatgctct tttagacaac tgttcaaatg
    68221 ttttcgaatt gtttttttga taaggacaat aaatgaacaa atttttggtt ttagtaaacc
    68281 caattactgt tcttttcatt agtgtcagtt gctatcaaaa cagcttgtca tagttcgtgc
    68341 gatcagtagc gagtattggt aaaactgaaa ccgtagatta tgaaaaaatg atctgttgag
    68401 cattaattaa tctgaagata agaagtcgat aaaaaggaga tacgatgccc aaactatcaa
    68461 agcgagtttt agaaatgaaa gagagtgtta ctctggctgc aggtgctaga gctaaggctt
    68521 tgaaagcgca gggccgcgat gtactgaatt taactttagg agaaccagat ttttttacac
    68581 ctaagcacat tcaagacaag gcgattgaat ctattcaaaa tggtacggct agcttttata
    68641 caaatgcttc tgggcttcca gaattaaaag ctgcgattgc cacatacctg aaaaatcagt
    68701 atgggtatca cttgtctcct gatcagattg tggcaggaac aggtgccaag ttcatccttt
    68761 atgccttttt tatggctgtt ttaaatcctg gtgaccaagt tctcattcca acaccatatt
    68821 gggtatctta ttctgaccaa gtaaaaatgg cagaaggtca gccgatcttc gttcaaggac
    68881 tagaagaaaa tcaattcaag gtaactgttg accagctgga aagagcaagg acaagtaaga
    68941 ctaaagttgt ccttatcaat tctccttcca atccaacagg catgatttat ggtgctgagg
    69001 aattaagggc cattggagaa tgggcggtgc acaacgatat tcttattctg gcagatgata
    69061 tttacgggtc cttagtctat aacggcaatc agtttgttcc tatttcaaca ctctcagaag
    69121 cgattcggcg tcaaaccatt acggtcaatg gcgtggctaa aagttatgcc atgacaggct
    69181 ggcgggttgg ttttgcagca ggtgaaccag agatcatttc ggcaatgagt aagatcatcg
    69241 ggcagactac ctctaacctg acaaccgttt cacaatatgc tgctatcgag gctttctgtg
    69301 gtagtcagtc atcacttgaa gagatgcgat tagcatttga agagcgcctt aatatcactt
    69361 atccattgtt gtgtcaggtc cctgggtttg aggttgttaa accacaagga gctttttact
    69421 tctttccaaa cgttaagaaa gccatggaaa tgacaggttt ttccgatgtg acaagctttg
    69481 ctaatgctat tttagaggaa gtcggattag ctgttgtgag tggagcaggc tttggcgcac
    69541 cggaaaatgt tcgtctgagt tatgctacag atatcgaaac ccttaaagaa gctgttcgta
    69601 gactgcatgt ctttatggaa agtaatgaaa ttaattaaat aaaaatagag agaaacttat
    69661 gtcaaaaaaa cttatttcaa ttgttgatgt taaagattat gttggtcaag aagttactat
    69721 tggtgcttgg gttgctaaca aatcaggtaa aggtaagatt gcgtttgtac agttacgcga
    69781 tggttctgct tttttccaag gtgtcgcttt taaaccaaac ttcattgaaa aatatggtga
    69841 agaatcaggt cttgaaaaat ttgacgttat taaacgtctc aaccaagaaa catctgttta
    69901 tgtaacaggg attgttaaag aggatgagcg ttctaaattt ggctatgaac ttgatattac
    69961 tgaccttgaa atcattggag agtcacatga atatcctata actcctaaag agcatgggac
    70021 agacttcttg atggacaacc gtcatctttg gttgcgttct cgtaaacaaa tggctgttat
    70081 gcaaattcgt aacgctatta tttatgcaac ttatgaattc tttgaccaaa atggttttat
    70141 caaatttgat agcccaattt tatcagaaaa tgcagcagaa gattcaacag agttattcga
    70201 aacagactat tttgggaaac cagcatttct tagccaatct ggtcaattat accttgaagc
    70261 tggagcaatg gctctaggcc gagttttcga ctttggtcca gtctttcgtg ctgaaaaatc
    70321 taaaacacgt cgccatttaa cagaattttg gatgatggat gctgagtatt ctttcttatc
    70381 acatgaggaa tcacttgacc ttcaagaagc ttatgttaaa gcattgatcc aaggcgttct
    70441 agatcgtgcg cctcaagcac ttgatatttt agaacgtgat gttgaggctc tcaaacgtta
    70501 tatcacagag ccattcaagc gtgtttctta tgatgatgct attacacttc ttcaagagca
    70561 tgaagcagat gaagatacag attatgaaca tttagagcat ggtgatgact ttggttcccc
    70621 acatgaaact tggatttcta attactttgg agtaccgaca tttgtggtga attacccagc
    70681 aagctttaaa gcattttata tgaaaccagt tcctggaaat ccagaacgcg ttctttgtgc
    70741 tgatctttta gctccagaag gttatggaga gatcattggc ggctcaatgc gtgaagacaa
    70801 ctacgatgct cttgtggcta aaatggatga actaggtatg gataaatcag aatatgactt
    70861 ttaccttgac cttcgtaaat atggctctgt tcctcatggc ggttttggta taggtattga
    70921 acgtatggta acttttgttg ctggtaccaa acatattcgc gaagctattc cattcccacg
    70981 tatgttacat cggattagac cctaataata caaaaagttc atgtcatcta tgaacttttt
    71041 gtattggtaa gaagtgagtg tgttataaaa acatcaatat gtcctaaagg agagataaga
    71101 aatagtagag tttgaaccta catcctttgt gaagataaat tttggaagtt tagtagatca
    71161 gttagcagat aagacaatat agctttgctc aagggatatt ttatagacaa gtatttggac
    71221 tacgattatc aaatagacac tctcatttga tactaaaaag gtctcgtcta ttcatataat
    71281 aggagagcta cgggagttat tattaaaatt agctgatttt tacagttcaa aatgtgttac
    71341 cactttttca cttcttagct ttcttatgta tgtggtataa tgaaggtgga cggttcgata
    71401 gagaaaggga aattgtaaat gtcagacaaa cacattaatt tagttattgt gacaggaatg
    71461 agcggcgctg gaaaaacagt tgccattcag tcttttgagg atctaggcta ctttaccatt
    71521 gataatatgc ccccagcctt ggttccaaaa tttttagaat taattgaaca aaccaatgaa
    71581 aatcgtaggg tggctttggt tgtcgatatg agaagtcgtt tgtttttcaa ggaaattaat
    71641 tctaccttag atagtattga aagcaatcct agcattgatt ttcggattct ttttttggat
    71701 gcaacggatg gagaattggt gtcacgctat aaagaaacca gacggagcca ccctttggct
    71761 gcggacggtc gtgtgcttga tggtattcga ttggaaagag aactcctatc tcctttgaaa
    71821 agcatgagcc aacatgtggt ggatacaaca aaattgaccc ctagacaatt gcgtaaaacc
    71881 atttcagacc agttttctga agggtctaat caagcctctt tccgtattga agtgatgagc
    71941 tttgggttca aatatggtct tcctttggat gcggatttgg tttttgatgt gcgttttcta
    72001 cccaatcctt attatcaggt agagcttcgt gaaaaaacag gactagatga ggacgttttt
    72061 aattatgtga tgtctcaccc agaatcagag gtgttttaca agcatttgtt aaaccttatt
    72121 gtccctatct taccggctta ccaaaaagaa gggaagtctg tcttgacggt ggctattggc
    72181 tgcacaggag gccaacaccg cagcgttgcc tttgcccatt gcttggcaga aagtctggca
    72241 acagattggt cggttaatga aagccatcgt gatcaaaatc gtcgtaagga aacggtgaat
    72301 cgttcatgaa aaatcctaaa atgactgtta taggtggggg tactggcatc tccattatcc
    72361 taaaaagcct tcgtaatgaa gcagttgata ttactgctgt ggtcactgtt gcagatgatg
    72421 gtggttcctc aggagaactt cgtaatgcca tgcaattagc tccgccagga gacttacgga
    72481 atgtcttgtt agcgatgagt gacatgccaa aattttatga gcgggttttc caataccgtt
    72541 ttaacgagag tgatggagcc ttggctggtc accctctagg caatctcatt attgctggta
    72601 tctctgaaat gcaaggctca acctacaatg ccattcaaat tttaaccaaa tttttccata
    72661 ttacaggtaa aatttacccc tctagcgagc aggccttgac ccttcatgct gtttttaaag
    72721 atgggcatga agtagcagga gaaagttcta ttgccaaata cccaggcatg attgaccatg
    72781 tctatgtgac caacacctac aacgaccaaa agcctcaggc cagtcgtaag gtggttgagg
    72841 ctattctaga aagtgacatg attgtcttgg gaccaggctc actgtttacc tctattttac
    72901 ctaatttggt cattccagaa attaaagaag ctttgcgcca gactaaagca gaagtggtgt
    72961 atatttgtaa tatcatgacc cagtatggtg aaacagaaca attttcagat gcagaccatg
    73021 tggctgtttt aaatcagcac ttaggaagag atttgattga tacggttttg gtaaatgtgg
    73081 ctaaggtgcc gcaggcttac atgaattcta acaaatttga tgaatacctc gttcaggttg
    73141 atcacgactt tgctggcctt tgcagggctg ctaagcgtgt gatttcgtct tattttttac
    73201 ggttggagaa tggcggagct tttcacgatg gtaacttagt ggtggaagaa ttaatgaatt
    73261 tagtgaggat agtcaagcaa tgagttttac aaccaaggtc aaagaggaat taattcactt
    73321 gtccacaggt gacaacaatg aattggccgc cattatcaaa ttatcaggca gcttgggctt
    73381 agctcaccaa agccttcatt tatccattac cactgaaaat gctaaaattg cccgctacat
    73441 ttattctctt attgaagacg cctatgttat cgtgccagaa atcaggtatc atcaaaagac
    73501 gaacctgcgc aaaaaccgtg tttacaccgt ctatgttgag caaggtgtgg aaaccatttt
    73561 agccgatttg aaattagcgg actccttttt tggtctggaa acaggcatcg aacctcaggt
    73621 tttatcagac gataatgctg gccgttctta tcttaaaggg gcttttctag cggcaggtag
    73681 catcagagat cctgagtcag gcaagtatca gttagaaatc tattcagttt atcttgatca
    73741 tgctcaagat ttagctcaac tcatgcaaaa atttatgcta gatgccaaaa ccatcgagca
    73801 taaaagcggt gcagttactt atttgcaaaa ggcagaagat atcatggact ttttaattat
    73861 aattggtgcc atgtcctgca aagaagactt tgaagccatc aaattacttc gagaagctcg
    73921 aaatgatatt aaccgtgcca ataatgcaga aacagctaat attgccaaaa ctatcagtgc
    73981 tagcatgaaa accattaata atattattaa aatcatggac acaattggtt tagaaagttt
    74041 accgattgaa ttgcaacagg tagcccagct tcgggttaag catccagact attccattca
    74101 acaagttgct gatgctcttg agttcccaat caccaagagc ggggtcaacc atcgcttgcg
    74161 taaaatcaat aaaattgcag atgacttata gaacattttt atcgtatgag cctttgttca
    74221 tacgattttt ttgtctaaaa gtcgttttcc attgtttttt tgaagtgtct gatgttctgt
    74281 gatatgataa aagggataat aacgtttgta aaggagactg ataatggcat gtacaactat
    74341 actcgtcggt aaaaaggcat cttatgatgg ctcaaccatg gttgctcgaa cagaagattc
    74401 tcaaaatggt gatttcacgc ctaaaaaaat gattgtggtg aaaccagaag atcaaccgag
    74461 acattaccgt tcggtgcaat cttcctttga aatggactta ccggacaatc ccatgactta
    74521 cacgtctgtt cccgatgcgc ttggtaaaga tggtatctgg gcagaagcag gcgtgaacga
    74581 ggctaatgtg gccatgtcag caactgaaac catcactacc aattctcgtg ttttaggggc
    74641 agatcctcta gtagcttctg gtattggtga ggaggacatg gtgaccttag tgctccctta
    74701 tatccgttct gcgcgtgaag gggttttgcg ccttggtgcc attttagaag actatggcac
    74761 ttacgagtca aatggtgtgg ctttttcaga tgaacatgac atttggtggc tggaaacgat
    74821 tggtggtcat cactggattg caagacgggt gccagatgat gcttatgtca ccaatcccaa
    74881 tcaatttggc attgatcatt ttgaatttaa caatcctgaa gattaccttt gctcagctga
    74941 tttaaaggac tttattgaca cgtatcactt agatttaacc tatagccatg agcattttaa
    75001 tccgcgctat gcctttggta gtcaacgtga caaagaccgt cagtataata cgccacgtgc
    75061 ttggatcatg caaaaattct taaacccaga aattgtgcaa gacccgcgca gctttgccct
    75121 tgcttggtgt caaaaacctt accgtaaaat aacagtagaa gatgtcaaat atgtattgag
    75181 tagtcactat caggacacgg gttatgaccc ttacggttca gaaggaactc ctgttagtaa
    75241 gaaagtcttt cgccctattg gcattaaccg taccagccaa accgctatct tacacattcg
    75301 tcctaataaa cctcaagaaa ttgccgctat tcaatggatg gcttatgggt caatgccatt
    75361 taataccatg gtgccttttt tcacacaggt gaagactatt ccagattatt ttgccaacac
    75421 ttacgaaaat gtgtttaccg acaatttcta ttggaccaac cgtctgattg cggctttggc
    75481 agatcctcac tacaatcatc atgaaactga tttggacaat tacttggaag aaaccatggc
    75541 aaaaggtcat gccatgttac atgctgtgga agcacagtta ttggctggtg aaacagtcga
    75601 tttggaagag gaaaatcaaa aaatgagtga ctatgtgcaa ggagaaacgc agacgctgtt
    75661 gaacaagatt ctctttgacg ctagcaatct aatgaccaat cgtttcagtt tgagcgatta
    75721 atagtgaagc taaggctgag caactgctta gcctttttta cgataacttt ttaggaaaag
    75781 taatcgcaaa aagacaaaaa cttggaaaaa aaatcaaagt atgctatact taactggtca
    75841 atttttaacc agttaataac aaaggaggaa tcatgaaaaa gaaaattctt ttaatgatga
    75901 gtttaatcag tgtctttttt gcttggcaac ttactcaggc aaaacaagtc ttagcagagg
    75961 gtaaagtgaa ggtggtgaca actttctatc ctgtttatga atttacaaaa ggggttattg
    76021 gtaatgatgg cgatgttttc atgcttatga aagcaggaac ggaacctcat gattttgagc
    76081 cttctacaaa agacattaaa aaaatccaag atgcagatgc atttgtttat atggatgaca
    76141 atatggaaac ttgggtttct gatgtgaaaa aatcattgac atctaaaaaa gtgaccatcg
    76201 tcaagggaac tggtaacatg ctcttggtag caggagctgg acatgaccat caccatgagg
    76261 atgctgacaa aaagcatgag cataataaac atagcgaaga aggacacaac catgcttttg
    76321 acccacacgt gtggttgtca ccataccgta gcattacagt cgttgaaaat attcgcgaca
    76381 gtctttcaaa agcttaccca gaaaaagcag agaacttcaa agccaatgcc gctacttata
    76441 ttgaaaaatt aaaagagctt gacaaagact atacggcagc actttcagat gctaagcaaa
    76501 agagctttgt gacacaacac gcagcttttg gttatatggc acttgactat ggcttgaacc
    76561 aaatttctat taatggtgtc acaccagatg cagaaccatc agcaaaacgt attgctactt
    76621 tgtcaaaata cgttaaaaaa tatggcatca aatacattta ttttgaggaa aatgcgtcaa
    76681 gtaaagtcgc aaaaacccta gctaaagaag caggagttaa agcggctgtg cttagtccgc
    76741 ttgaaggttt gactgaaaaa gagatgaaag ctggccaaga ttactttacg gtcatgcgta
    76801 aaaaccttga aaccttacgc ttaaccactg atgtggctgg taaagaaatt cttccagaaa
    76861 aagacacgac taagacagtt tacaatggtt atttcaaaga caaagaagtc aaagatcgtc
    76921 aattatctga ctggtcaggt agctggcaat ctgtttaccc ctatctacaa aatggtactt
    76981 tagaccaagt ttgggactac aaggctaaaa aatctaaagg taaaatgaca gcagccgagt
    77041 acaaagatta ctacactact ggttataaaa ctgacgtgga acaaatcaaa atcaatggta
    77101 agaaaaagac catgaccttt gttcgtaatg gtgaaaagaa aaccttcact tacacatacg
    77161 ccggcaaaga aatcttgacc tatccaaaag gaaatcgcgg ggttcgtttc atgtttgaag
    77221 ctaaagaagc agatgctggc gaattcaaat acgttcaatt cagtgaccat gccattgctc
    77281 ctgaaaaagc aaagcatttc cacctgtact ggggtggtga cagccaagaa aaattacata
    77341 aagagttaga acattggcca acttactacg gttcagactt atctggtcgt gaaatcgccc
    77401 aagaaatcaa tgctcattaa tcttaactca ctaagcaaat cttcttttaa ggaggtttgc
    77461 tttttctttg tggagtaaaa aaatttaata attctcaaca ttaatttgac ggacacttat
    77521 gattataata tactttaagt ggttataaca agttagaggt gaataagatg ccaaaagaac
    77581 aaccactcta tctacagatt gttgatgact tggaagtgaa aatcaaaaaa agcatgacag
    77641 aaaacgataa gttgttgtca gaacgagaat taagtgacct ttacggtgtt agtcgtatca
    77701 cgattagact gactcttaag gaattggaat tacgagactt aatttataaa aagcagggca
    77761 aggggactta tgtttcagga atcaaagaac ctgccactga tttatcaagt acttacagct
    77821 ttacagagca gatgaaaaaa atggggaaaa ctcctaaaac agagattctt tcttttgaac
    77881 agtatcaggt aacaccttac ttgtctggtc tcttagagct tgatcccgat acagaagttt
    77941 ttgaattaga acgcctaagg attgcagatg atatgccctt gatgtttgaa cgatcctata
    78001 ttcctgctca gccttttcag gggttaagca ttgcggactt aaagcgtaaa gctttgtacg
    78061 atatctttgc aaaggactat caagaaacaa tccgtcttgc agaagaagag ttttatgcca
    78121 gcattgcctt ggactatgaa gcaggtctct taggcattaa aaagggagat cctgtcttac
    78181 atattattcg taaaacttat aatgataaaa atatcttaat tgaattgact ttcagcattg
    78241 caagggcgga tcagtttagg taccgggtgc aacatcaccc taatggttaa ggaattggag
    78301 gttaggacat gtttacaaaa acgcaggaag ctttggaggc tcttggtgca gctatcacta
    78361 ccaaggaaat taaacaagaa ccccgtttat ggcaagaaac catgacgttt tttgaagaaa
    78421 caagagattc tctggattct tttttaaaga gagtttgtaa cagcgctaac agaaataacg
    78481 ttcatgtcat ctttacaggt gcgggtacat ctgagtacat cggtaatacc atttgccctt
    78541 acttgaagaa ggtggggaat cggcagcgct atctctttga gagcgttgct tcaaccgatt
    78601 tggttgcggc gccagattat tatcttgttg aggaagagac ggtactatta gtctcctttg
    78661 ctaggagtgg taatagtcca gaaagtgtag cggctgttaa cctggtcaat caactagtgc
    78721 caaatagtta tcatttaacc attacctgcg ccaaagatgg agaactggcg aaaaaagcac
    78781 agcaagatga gcgttcttac ctttatttga tgcctgaaga cgctaatgat gctggttttg
    78841 ccatgactgg tagttttacc tgtatgatgc tagcggctct tttgattttt gatgatgcta
    78901 acagtatagc tcagaaagaa gcttatgtga ctgatatgat tcttgctggg caagctgtta
    78961 ttgaccaaga aagacggcta caagagctag ctgatttagg atttgaacgt ttagtttatc
    79021 taggttctgc tggtttagcc aagttaaccc aagaagctca attaaaaatg ttagaattga
    79081 cagctggaca agttgcgacc ctctacgagt cctctatggg ctttaggcat ggtccgaaat
    79141 cttttattaa tgaccgtacc ttagtcattg gatttgtcaa taatgatgct tacgtcagac
    79201 agtacgattt ggacatgtta gaggaaatcc aagcagatgg cattgccctt aaaatcttgg
    79261 ctctattgca aggaggggat atcaactttt cagaggacca atttcgacta gacacccgtc
    79321 acttattgcc agacgcttac ttagcttttc ccatgatttt agtcgcgcag accttggccc
    79381 tcttaacggc cgttacatta ggaaattccc ctgacacccc atctgcgaca ggaacggtta
    79441 atcgtgtggt caaaggagta acgattcacc cttacccgac tagtagtcgt caatgcaaca
    79501 aagcttaaag cttttgtgta gaagccgtaa aacgaaatga ttttgtgcta gtaggtcaaa
    79561 agaaaaaccc tcctgataca ggaaggtttt ttgtattgtc ttgcttattt tgctgcgttt
    79621 gcgtctttga gaccgtattt tttgttgaag cggtccacac gtccatctgc ttgagtgaac
    79681 ttttgacgtc ctgtgtagaa tgggtgtgaa tctgatgaaa tttccacacg gataagtggg
    79741 taagtttcac cttcaaactc aacagtttct ttagaagctt ttgttgagcc gctaaggaac
    79801 tggtaacctg tagttgtatc taggaaaaca actggacgat aatctggatg aatgtctttt
    79861 ctcatcttaa aaaattcctt tctgccatga cacttaatgc atcatagtta ttaaccattc
    79921 tagtgtaaca aaacttgaat gacttgacaa ggcttttctt tccttatttt ttaaaaatcc
    79981 taaatctctt ggcaaacagc gatgagttct cggaaaatag cttgattttc ttctaaatta
    80041 gctgagttgg ctccgctagc aaggggatgc ccccctccac cgtgacgctt agcaatgcca
    80101 ttaataatct tttctttact gcgcatacgc acacggtagt tgccgtcagt taactcaaca
    80161 aaaatagccc aagcttgaac gttatcaatt ttaccaggag cacagacaat ggcagagctt
    80221 tctgctaggg tcacgtcaaa atgttttaag gtttcttggc tgacaaggac ataagcagcc
    80281 ccactctcat caattgttaa atgctcaaag acgtagcttt gcagctttgc tattttcaaa
    80341 ggaaacgaat ccatttgcct tgaaatcgca gcaaagtcga attcgaaatg tctgagttgg
    80401 ctagcaatgg aaagggtttt actagtggtt gaggcataaa gaaatcgccc tgtatcacca
    80461 acgataccgg tgtataagag cttagcagcc ttgtcagaga gagtaagatt ctgactaaag
    80521 gcaaagtctg caatgatttc acttgcgcta gaagcgcttg tgtccacata atagaagtca
    80581 ccatacacat catcgttggg atggtgatca atcttaatta agcacttccc cagtgtgtag
    80641 cgctcatcat caatccttgg tcgattcgct gtatctgtaa tgatgaccaa agcctcttta
    80701 tagtctttgt cagtcacctg atccatttgg ctaatccaag ctaaactagg ctcatcaaaa
    80761 ccagtcatca aaaccttttt gtctgggaaa ttttgtgcaa taatttcttt caagccggcc
    80821 tgactaccaa gagcatcagg gtcaggattt tgatggcgat ggataataat agtttggtga
    80881 gcttttattt tatctaaaat tgtttcaaaa gttgttatca tgctttaatc tttctttttc
    80941 aaaaagagga aaataaccgt ttaacatagt cttcaaaaaa cggtttgtgt catagggagg
    81001 tgtgcgttat gttaagtggc taatgctaga attttttaag attgtcaaag accataaatt
    81061 gacattttat ctgaaaatca tatcctattt tattatagca taaaagtaag ctctagataa
    81121 tggtaaatta atctaggaag aaaagaggtt agttatcagt tatgatacta tcaaagctag
    81181 tcttgcaaat gcaagtgaaa aaatagtttt taagtgtttt aagcaatcat atcaaccttc
    81241 tcgttaaaca attagtgctt ttcctaaaaa agtgtgctaa aataaacata gtttagtaat
    81301 tttgggagga atttatggca ttagcaaaaa tcgtttatgc cagcatgacg ggaaatactg
    81361 aagaaatcgc tgatatcgtt gcaaataaat tgcaagaatt gggccatgat gttgacattg
    81421 atgagtgcac aacagttgac gcttcagagt ttgagaatgc tgatatcgct gtcgttgcga
    81481 cttatactta tggtgatggt gacttaccag atgaaatcgt tgatttttac gaagatttac
    81541 aagatttaga tttagaaggt aaaatctatg gcgttgtcgg ctctggtgac actttttatg
    81601 actatttttg caaatctgtt gatgactttt cagagcaatt tgcgcttact ggtgccatca
    81661 aaggtgcaga gcctgtcaaa gtagacttgg cagcagaaga tgaagacatc gatcgtttag
    81721 aggcctttgc agagcaactc tcacaggctg ttaataatct ataaaactat ttagtaaaaa
    81781 tgtcagggac ttccttggca tttttagatt tttaacctaa aataaaggga atgtcacttc
    81841 agggtaggaa ttgaaaaaaa caatcagctt caccttgctt ctgatcctct tattaactat
    81901 aataaaaaga taatctaata catctagaaa aggaaagtta tgcgtttaga aaagatacga
    81961 caagaaatca atggtattga tcaccacttg gttgccttat tagaaaagcg gatggcactt
    82021 gtagagcaag taacagctta taaactagcc aatcacttgc ctgtcttaga tcaggcgagg
    82081 gaaaatcaga tcctagatag ggtttcttat ctcgttaaag accaagcatt tgagccagct
    82141 atccatgaga cgtttaaaac cattatgtct ctttcacggc agtatcaaac gcaacactta
    82201 acaggtggtg acattaatga ttaaatcaat tgcaacactg cctaaacctt ccttgaaaga
    82261 agtgttagga ctagtaggat tagcacttcc catagggggc gcggttggag tggttgatgt
    82321 tatttttggc aaagggcttt tgtttctttc cgaatatcgc gatcaccacc ttttcttgct
    82381 tcttccattt cttgccctag caggccttgt tatcgttttt ctttacgata agttaggcaa
    82441 agaggttcgt caagggatgg gattggtttt tcaggtaggg catggtcaaa aaaatcagat
    82501 tcctcctatt ctcattcctc ttattttgtt ctcaacttgg gtaacccact tatttggagc
    82561 gagtgcgggt agagaagggg tagccgttca aataggagct actatctctc attattgtcg
    82621 gagatttgtg actagtcaag aagccgcacg acatcttttg attatgggga tggcagccgg
    82681 ttttgcaggg ctttttcaaa cgccaattgc tgctgtcgta tttgccctcg aggttttatt
    82741 agtaggaacg cttcgttatt ccgctttatt gccttcctta gttgctgctt acgtggcttc
    82801 ttggacttcc catgccttgg gattagagaa atttacgatt gttcttgaag aaacattgac
    82861 cataactccc ttaacattgg ttaaattaat tgggttaggc cttatttttg gtctggtggg
    82921 aaatagtttt gcctatttac ttggctggtt taaaccttac ctcagtcaaa agctaccaaa
    82981 tccttatttc cggattgctt ttatcggtgc tttgttatct atctgtctga tgattggtca
    83041 cgtcggaaga tatagtggtc taggaaccaa tttgattgcg gcagcttttt ctggccaaac
    83101 tatcctaact tacgactggc ttttaaaaat gatcgtgacg gtgattagct tatctgcagg
    83161 ctttcaaggt ggtgaagtga cgcctctatt tgctattgga gcttctttag gcatcgtttt
    83221 ggccccttac ttaggtcttc ctgtactgtt ggttgctgca cttggttaca ccacggtatt
    83281 tggaagtgca acaaatacct tttgggcccc tatctttatt gggatagagg tctttggtcc
    83341 agagaatgcc ctagcatatt ttgtcacctc ggctgcagcc tatatggtta gtcacagaca
    83401 ttccatttac agttatcaaa aagtagtcat gatcaattta aaagacatga cggtaaatca
    83461 gatggattta aaaaaatagc tttacaataa agaagctttt tgttagaata aatctcgtgt
    83521 gtaatggaca cacgaaaatt acggctaatc cgctaagaca agtacttaag attagtaaga
    83581 taggagaata aaaatgaatc cattaatcca aagtttgaca gaaggtcaac ttcgctctga
    83641 tatccctaac ttccgtcctg gtgacactgt tcgcgttcac gcaaaagttg tcgaaggaac
    83701 tcgcgaacgt atccagatct ttgaaggtgt tgttatttca cgtaaaggtc aagggatctc
    83761 agaaatgtac actgttcgta aaatctcagg tggtatcggg gtagagcgta cattcccaat
    83821 ccacacacca cgtgttgaca aaatcgaagt tatccgccac ggtaaagtcc gtcgtgcgaa
    83881 actttactac ttgcgtgcat tacaaggtaa agcagctcgt atcaaagaaa ttcgtcgtta
    83941 gtttgaaccg aaacgtaacg taatagaata aaaagactag agtctctagt ctttttatgt
    84001 cgtcgtgaca atgtgacaat tggtgattaa cgctatgctt gtaggacact ttgaaagttc
    84061 cttagcagtt ataattagta tattgtaata acaaaatgaa gcaaaataaa ctttcagtta
    84121 tctgatattt catcttgcat taccttattt tctaggttaa aatagaagac aaggtgagta
    84181 taagatagac cccttagttc aatggatata acaactccct cctaaggagt agttgctggt
    84241 tcgattccgg caggggtcat tattgtcact gaaaaagcct ttacatcaaa ggctttttgt
    84301 tttattccgg ttttaaaagg gtcagtttgt ttatttataa tttctttcat gtttacagtt
    84361 gtgtgactgt aaatagataa tgttgttttt ggatcgctgt gaccaactct atccattatc
    84421 gcatttagcg gtatcccttt ttctgctaaa aatgatatat gcgagtgtct aaataagtgc
    84481 gtgtgataat ctccgtaaat tttcaatcgc ttattgatgt acgcgtttaa aattggtaaa
    84541 ccttttgaat atggaaagct gttagcactc tgcttgtgat taatctatcg tatgttaaaa
    84601 gtgacattta aattaaatca ttttttatac atatatttca aaaggattta tcatattgga
    84661 aaatagcggt gcttctattg gcattttact attgacagga atttccctgc cttttgtctc
    84721 ctaaagaaga tcagctttga tttctaactt gattagagtg ggcttggtac tgtttatgaa
    84781 ttatcagtac atactttctg gagatcaaaa aggaaaggaa cagctaaaga ggtgtatgtg
    84841 ttaccattag aggaatagaa catcgcaaga ctcgtttatt cagtcattac gatacctgtt
    84901 ttatttgtga aataactata atattaagtg aatttgtgat ataatgaaag gtatgaatta
    84961 tcaagattat atatgggatt tgggaggtac cttactcgat aattacgagc tttcaaccca
    85021 agcttttgtc caaacgctag cttttttcag ccttccagga gatcacgatg ctgtttacca
    85081 aaaattaaaa gaatcaaccg ctatcgctgt ggcaatgttt gctcctaatg agccagaatt
    85141 tttgcatgtg tataggctaa gagaagcaga caaattggca caacccattt ggtgtttggg
    85201 agctaaagaa attttgggaa agatagcgac ttcaggttcg cgaaattttt taatttctca
    85261 tcgagattgt caggtgaacc aacttttaga gcaagctggg ttgctaatct attttacaga
    85321 agtcgtgaca gcttcaaatg gctttgctcg gaaaccaaat cctgaaagtt tgttttattt
    85381 aaaagaaaag tatgatatta atagtggatt agtaattgga gatcggctaa ttgataaaca
    85441 agcaggacaa gcagcgggtt ttaatacctt gcttgttgac ggtagaaaaa acctattgga
    85501 gatagtaacg tagatgattg aagaaaataa acattttgaa aaaaaaatgc aagaatacga
    85561 tgccagtcaa attcaggttc tagaagggct ggaggctgtc cgcatgcgtc cagggatgta
    85621 tattggctcg acagctaaag agggtttgca tcatttagtc tgggaaattg ttgacaactc
    85681 aattgacgaa gcattagcag gttttgcctc tcatattaaa gtctttattg aagcagataa
    85741 ttccattaca gtagtagatg atggccgtgg aattccagtt gatatccaag ccaagacagg
    85801 acgtcccgcc gttgaaacag tttttacagt cttacacgca ggtggtaaat ttggtggagg
    85861 cggctataag gtttctggag gattacatgg tgtagggtca tctgttgtta atgctttatc
    85921 aacacaatta gatgtacgtg tttataaaaa cggccaaatt cattaccaag aatttaaacg
    85981 cggggctgtt gtagcagatc ttgaggtcat tggaaccact gatgtgactg gcacgaccgt
    86041 acactttaca cccgatccag aaatttttac cgaaacgact cagtttgatt acagtgtttt
    86101 agcaaaacgt attcaagagt tagccttttt gaatcgtggt ttaaaaattt ccattacaga
    86161 taagcgctca ggtatggaac aagaagaaca tttcctttat gaaggtggaa ttggttctta
    86221 tgttgaattt ttaaatgata aaaaagatgt tatctttgaa acgcccatct atacagatgg
    86281 tgaattagaa ggtattgcag ttgaagtagc catgcaatac acgactagct atcaagaaac
    86341 agtcatgagt tttgctaata atattcatac tcatgaaggt ggaacgcatg aacaaggctt
    86401 tagagcggct cttactcggg tcatcaatga ctacgctaag aaaaataaaa ttcttaaaga
    86461 aaatgaggac aatttgacag gagaagatgt tcgtgaaggt ttgacggcgg taatttctgt
    86521 taagcatcca aatcctcaat ttgaaggtca aaccaaaaca aaattgggca actcagaagt
    86581 ggttaagatc actaatcgtc tctttagtga ggcctttcaa cgttttcttt tggaaaaccc
    86641 acaagttgct cgtaagattg tggaaaaagg gattttggct tctaaagcta gaattgcagc
    86701 taagcgagcc cgcgaagtca cccgcaaaaa atcaggctta gaaatttcaa acttacctgg
    86761 aaaattagca gactgttcgt caaatgacgc taaccaaaac gaacttttca tcgtcgaagg
    86821 agattcagcg ggtgggtcgg ccaaatcagg tcgtaaccga gagtttcaag ctatcttgcc
    86881 tattcgcggt aaaattttga acgtggaaaa agcaactatg gataagattc ttgccaacga
    86941 agaaattaga agtctcttta ccgctatggg tacaggtttt ggtgcagatt ttgacgtgtc
    87001 aaaagctcgc taccaaaagc tggttatcat gaccgatgcc gatgtggatg gcgctcatat
    87061 tagaacctta cttttaacct tgatttaccg ctttatgaga cctgttctag aagctggcta
    87121 tgtttacatc gcccagccac ctatttatgg tgttaaggtc ggtagtgaga ttaaagagta
    87181 tattcagcca ggtattgatc aagaagacca attaaaaaca gctcttgaaa aatatagtat
    87241 tggtcgttca aaaccaactg ttcaacgtta taaaggtctt ggggaaatgg atgaccatca
    87301 actttgggaa actactatgg atcctgaaaa tcgtttgatg gcgcgtgtga cagttgatga
    87361 tgccgcagaa gcagataaag tatttgatat gttaatggga gatcgtgttg aaccaagacg
    87421 tgatttcatt gaggaaaatg cggtttatag tacactggat atttagtcac ctttttagtt
    87481 tcacaaggaa tctgctacca aagaggacga attgactaaa aatcatgatg catgatgcca
    87541 acagctttgt tagttagtac gtcttcatct tgagggacag cgttaatgca taggtattga
    87601 gaccgcccct taatacctat gttagtcctt attaagaaag ccttttgagt cgctggtacg
    87661 agattgttga attagtcaaa tatattttga aatgcatttt aaagtatgtt ataatcgtaa
    87721 tgttatagtg tattttaaat aaaattttaa taaaaggcga ttgaggaatt tcagttttta
    87781 gttattactg gaacaatgtt gataaatcgt gtctaaataa taaggagatt cagatgtcaa
    87841 gcggaattat cttgctgatt gtggctatag tcctactagt gattatcgcc tatctagtgg
    87901 gtgtcatcat acgaaagcgt aatgattccc taattaccag tctagaagaa cgaaaacagg
    87961 ccttgtttgc tttgcctgtt aatgatgaaa ttgaagaagt aaagtcactt catttgatag
    88021 gacagagcca aacctctttt cgggaatgga atcagaaatg ggtagactta actgtgaatt
    88081 cgtttgcaga tattgaaaat catatttttg aagctgaaaa tttgaatgat acgtttaatt
    88141 ttattcgcgc caagcatgag attaatagcg ttgaaagtca gcttaatctt gttgaagaag
    88201 atatcgcttc tattcgtgaa gcacttaata tcttaaaaga gcaagaagaa aaaaatagtg
    88261 ctcgtgtcac ccatgctctt gatttatatg aaaagctcca agcttctatt tctgagaatg
    88321 aagataattt tggttcaact atgcctgaaa ttgacaaaca gatgaaaaac attgaaactg
    88381 aattttcaca gtttgtcgca ctcaactcat caggtgatcc tgtagaagct tctgaagttc
    88441 tggatagagc agaagagcat actattgctc tagggcagat tacagagcag attccagcta
    88501 ttgtggccaa gttggaagat gattttccag atcagttaga tgatttggaa acaggatatc
    88561 gccgtttact tgaagaaaac tatcattttc cagaaaaaaa cattgaggca cgttttcagg
    88621 agattcgtga gtctattcgt gccaattcat cagagttagt tacacttgac ttggatcgtg
    88681 ctagagaaga aaacacgcat attcaagaac gcattgattc tctttatgaa gtctttgagc
    88741 gcgaaattgc cgcttataag gtagctgcta aaaatagtaa gatgctacct cgttacctag
    88801 aacatgtgaa acgtaataat gaacaactca aagatgaaat tgcacgttta tcacgtaaat
    88861 atattctaag tgaaacggaa agtctgactg ttaaggcatt tgagaaggat attaaagaga
    88921 tagaagacag tacacttgct gttgcagaac aatttggttt acaagaaaaa ccattttcag
    88981 aactgcaagt gacttttgaa cgcagtataa agacgcttac taatgtcgag tcaggtcaaa
    89041 tggatgtttt tgcagcagtt aaagatattg aaaaaattga atcacaggca cgccataacc
    89101 ttgatgttta tgttactcag cttcatatga ttaaacgtta tatggaaaaa cgtcacttgc
    89161 ctggaattcc acaagacttt cttagtgctt tctttacaac gagttcacaa ttggaagctt
    89221 tgatggatga gcttagtaga ggacggatca atattgaggc agtgtcacgt ttgtcggaag
    89281 ttgcgacggt tgctattgct aatctagaag atttaaccta tcaagtggtt caaaatgcta
    89341 ccttgactga acaattacta caatattcta atcgctatcg ttcttttgaa gcaggagttc
    89401 aaagtagttt tgaacatgct ttgagacttt tcgaagtaga aaatgattat caggcttctt
    89461 ttgatgaaat ttcttatgct cttgaaacag ttgaacctgg ggtaacagat cggtttgtta
    89521 actcttatga aaaaacacga gagcacattc gtttttgata cttgaaagtc gtgatattct
    89581 cacgactttt tattagcttt ttggaccaat acgtgttttt gactagaatc ttctttttaa
    89641 tgatcaaacg aagaagtagt aacagtgttt tttgctattg agaggatagt tattttttca
    89701 aaaatctttt ccaaaaggat ttggtttttt caggagtttg tttgctaagt tgatcgtttt
    89761 ttgtctgctt taagatgact tctaaacgtg tttccttcag atttattgcg tggtcggtat
    89821 gaaggataaa cgcaaaaggt gaagtcatat gcgtttctgt aataatagta acaggtaaat
    89881 ggttttcttt tgctaatttc atatagagta tttgaagttg aggtgccagc ttggaagaga
    89941 tttttaagtg taaaggttga tagactaact gaaggctcgg taattctctt ttcaaatagt
    90001 cttttactgt tttagtttga gcttcgtcta ataaagcact taaaacgact cgttcagcat
    90061 acgttcctag atagtagcgt tgctgctcag gatttaatct tctttctccc caggctcctt
    90121 ttaatagctt atcttctaaa ttagtcatag ataccctcgc ttctttataa tagtttcttt
    90181 attatatcga tttctacaat aaaataccaa tttgaaaatt ttcggtaaat gtgttaaaaa
    90241 acaagaaaga aagtgatttt tcttgcaaaa aacaaaggaa gcttttcatg agattgcttt
    90301 ttaagttgat taaaggccta gtttgtggta ttatgaacat gtaaaatatt aaaactcata
    90361 aggagagtat tacaatgtca attattactg atgtatacgc tcgcgaagtc cttgactcac
    90421 gcggtaaccc aacacttgaa gtagaagttt atacagaatc aggtgcattc ggacgtggta
    90481 tggttccttc aggagcttca actggtgaac atgaagccgt tgaacttcgt gatggtgaca
    90541 aatctcgtta ccttggtcta ggtactcaaa aagcagttga taacgttaat aacattatcg
    90601 ctgaggcaat catcggttac gatgttcgcg atcaacaagc tatcgaccgt gcaatgatcg
    90661 ctcttgacgg tactcctaac aaaggcaaac ttggtgctaa tgctattctt ggtgtttcta
    90721 tcgctgttgc tcgtgcagct gctgactatc ttgaagtgcc actttacact taccttggcg
    90781 gattcaacac taaagttctt ccaactccta tgatgaacat catcaacggt ggatcacact
    90841 cagatgcccc aattgcattc caagagttca tgatcatgcc agttggtgca cctactttca
    90901 aagaaggtct tcgttggggt gctgaagttt tccacgctct taagaaaatt cttaaagaac
    90961 gcggacttgt tacagctgta ggtgacgaag gtggatttgc tcctaaattt gaaggaactg
    91021 aagacggtgt agaaactatc cttaaagcta ttgaagcagc tggttacgaa gctggtgaaa
    91081 acggcattat gatcggtttt gactgtgcat catcagaatt ctacgacaaa gaacgtaaag
    91141 tttacgacta tactaaattt gaaggtgaag gcgctgctgt tcgtacatct gcagaacaag
    91201 ttgattacct tgaagagttg gttaacaaat acccaattat tactatcgaa gatggtatgg
    91261 atgaaaacga ctgggatggt tggaaagttc ttactgaacg cctaggcaaa cgtgttcaat
    91321 tggttggtga cgacttcttc gttacaaaca ctgaatacct tgctcgtggt atcaaagaaa
    91381 atgcagctaa ctcaatcctt atcaaagtta accaaatcgg tactttgact gaaacgtttg
    91441 aatctatcga aatggctaaa gaagctggat atactgccgt tgtatcacac cgttcaggtg
    91501 aaactgaaga ttcaacaatc gctgacatcg cagttgcaac aaacgctggc caaatcaaaa
    91561 caggttcatt gtcacgtaca gaccgtattg ctaaatacaa ccaattactt cgtatcgaag
    91621 atcaacttgg tgaagttgct caatacaaag gtatcaaatc attctataac ttaaaaaaat
    91681 agacggtaag acagaaatcg gtcattcgta gaatgcgatt tcgtcgtcgc acctccgtca
    91741 ggctgactag gttggtcacg acaaaaggag tgaacatcca gtcagctacg acgcaaaagt
    91801 taaagattaa agaatagaaa gcttgggaaa atcccaagct ttttgctttc taaatagtaa
    91861 aaatttactg tgggctaatt tatcctgagc taatgtatta gcgaggtaaa gttactgaag
    91921 aagacttgga tttgtactgc ctctaaaaag ttggacacta tattttaaat acaggactaa
    91981 gtccttttat accaattgtc aagcacatca aggttttaac tgaaaaaatg ttttagacaa
    92041 tagcctaggt ttagctgttg tcttacttgt tgtgctctga ttagcataaa aaagtgtaca
    92101 agaaaaaaac cttgcctagt atttttaaga tcaaggtgtt acaatgatag agcaacaacg
    92161 actttaatga ttttgggtcg aagcgtaatt gtaaagtttg ttatgcgtta tgaggtaaag
    92221 cattgtctga caaggcaatg tctagaggca atcgtatgtg gcttggttga agctgtttgc
    92281 gattgccttt ttcgtttctc atagaagtct gcgatatgac aaggattggt atgactagca
    92341 aaagcaatgt catggataca cttgaaaaga atctttggag cataaggatt cccacgtttg
    92401 gtaatgtgct cttgagctag atagttgcca gactcataat gtctaaagtc aatcccaatg
    92461 aaagcattaa tttgattagc agattgaaaa cgacgaatag caccgagttc gccaataata
    92521 cttgttgcag ttgtttctac gatacttgga atagagcgta gaatcttgtc ttctggtaaa
    92581 ggttgagccg acgccaccat cttatcaaaa atagcttgac gacgttcaga aagtctaagt
    92641 aattctttgg catagtagcg aacctcttct atcatcggag aggttttcgt aacagtaaaa
    92701 taagactgct tggctaatga gacaagtttt tccactaagt agatcccacg cttgtcagag
    92761 atacgtttag aggtagattg acggatgata gctgacaatg ctttgtcagc tagctccagt
    92821 acaaagctat tacatgaaaa aagccgttac cacattccag tattactcac cagttggtgc
    92881 aaataagatg tgttccagtt caggaaaagt gacttgtaag atcttgtgaa ggcgattctt
    92941 aactctcgaa caatattatc ctcagtcaag ttttgataga agcgactcaa gtcacgtagc
    93001 agctgataaa cttcttcctg aacgtaagtt ggttttctaa ctagaataaa ttgagactga
    93061 gccaattttt cagtgtctaa cttatccgct ttacgcaccc gtagactatc tagttttcta
    93121 aaggattgag ttgtgtataa gcgtagccat ttttctcaag gaaggactga agccgacgag
    93181 aatagactcc tgttgtgatg gtctcccttt tgccttttaa acaatagtat agccgttttt
    93241 caaaatgtta ttaatgattt tttcctttat tccagaagaa taagtctgat actgtttctt
    93301 attaataatc tcaatgccct aacaatccat cagtcgaacg gtatttctca aattactgca
    93361 gttgactctt gcgttcagtt ccctcacctt gtggatgccg tttagaacaa tattagcttg
    93421 ctgagccttt tggtaatgtg aacaaagcat ctttatcact caaggagaag acaggttctt
    93481 gtggtaagtg tccaacaagg tcacgataaa ctcatcgtac cgtttttggc ggaagtctag
    93541 aaatgcctta tgaatgtaag cctcagaaac gtctctaaaa ctaaacaaga aatacaagaa
    93601 caaatgccct tgattctggt acaaatgctg tatcaggttc aggtattgcc tatctgcgat
    93661 aatgacactc tgcttttcct taacaatatc tttgaaagga atgatttcga cattgacagg
    93721 cataaccgtt gcaatagctg gcgggaagta aattgagagt gcattggtca tcaaatccag
    93781 cgcagcagtg ttattggtca aaagatagac aggtatcggt ggcaaatatg tttttaggag
    93841 ttcctctaac tgtatcgtga agagcaataa atgataagac ggcagtttcc ccacgatgcc
    93901 ttctgcgctc atccattcct caacgatggt ttttagagta ttgtagaagc tcttgtttcg
    93961 tttttgctgt cttctgaggt aatggaacaa gtgtatgtca ggtaacaaaa cttgaagatt
    94021 actgataaat agacgtgaga aggaaaccaa aatccgtttg aaaggaaggg agtttaggat
    94081 attattgcct agtagtggac gcagggatgc tttcaaggtt tttccatttg ttttgtcatc
    94141 accaactcaa acaattcttt cactttttta ggtgtccatt tatccttatg gaaaggatta
    94201 ttggtggtgc aaaaacataa aaaaatataa tccaaatcct catcagttaa ctcaggatgg
    94261 taccattttc cgatgatttc ctgactggtc attttgatat ctcgatagat agacagtttt
    94321 ttcaagtgtt tgaatgcatc tgtctgaggg atccccaagt tatcatgtcg ccgtttccat
    94381 ataagggata tcaaaatggc aaagtatgaa aattcataag gggctttact ggcatcatta
    94441 agtgtggtgg cttgattgga gtttataatc agcgaaacca ctttattcat tgatgtttta
    94501 tcaaaatcat aaatggtcat accaaactga tagtgcaaca aggcgatcag aaagcggata
    94561 cggtattctg gtccaacaac atggttttgc cgaacgttta aacctacctt tttcaagtat
    94621 ttccgacaat tggtcctgat acggtaagcg gtggcttggg aaatatactc tcgtttaatg
    94681 aagtcgtgta ggctcagctc tcctggttca attaaaaaac ataacatctt taagaatatc
    94741 gaggtttgat agagtttctt aaaataaggc attttaagtt ggtaggtctt ataggggata
    94801 gaaacagtgt cgtcacaaat ggttaaggtg agggtgtctt ctaaatcctt aatcatttca
    94861 aagagtaagt tgtagacacg ttgttttttg agttcggttt cctgacacaa ctggtctatg
    94921 gagacttcgg aaacgtctaa caaaatgttg agcagtgata atttatcttg taatttggtt
    94981 tctagatgaa ggtgtaacat aactgaactc ctttcatttt tatagcagaa actcgtattt
    95041 atttaattat cacataatta aataaaacag tcaaataatt caatggtgac gcgtgtttaa
    95101 ggagtattga gaatgtcaga tataagcaaa atgcagctga atattcttaa ttttaggtat
    95161 gaaaaagcgt cgggattgat aaaaaatcta ttgaattggg taaatttaag ttgatataat
    95221 aagttgatta gaaaaattaa caattcattt aaattctaat cagctgtaac gttccggggc
    95281 gtgttaaact gtctgaacat agaaaataca agtttctacg gtgactaaga taagttaagg
    95341 aggattcctt aaattctgtg ataggaacgt aaactctcta caagagtaga gcacgtcatc
    95401 agtcagtctg ggtgtctact ggctgacaac gtcaaataag ataggcatga aaaaataagg
    95461 gggaatacag aatgttttta aaacaccaag atgtgaaaca aaaaaattgg agaatgcgta
    95521 aggtcaaaaa agtctttgtt agttcatgta tgcttttaac agtgggcctc ggagttgccg
    95581 tacctactgg attcagccaa tctaatggcg tgatggttgt aaaggctgcg gaagtgccgg
    95641 cgacagattt atcacgtcag gcgtctgatt cggagagggt agatgaatcg tctttattgc
    95701 agaaagaaaa cttatcagta gattcattta aattagaaaa tttaaatgga tgggaagctg
    95761 aaaatgatac agcaggtaat ttggggaaat ttaaagatcc agatagttcg ggctatcaaa
    95821 atattttgac atcatctgga aagaatatca gtgtagctgt tgctcccaaa ggttcaggta
    95881 aaatgaacat taaagtaact aaaagatcaa attttcaggg tggatattat gtaggtggtc
    95941 ttagaactca aactccggta ttgaagttaa atgatgttta tcgatattct tttacaacta
    96001 aaaaattatc aggaaattct tcagagttca aaacgagagt taagcccgtt gaatctaata
    96061 ataaactagg gaaagagctt gttattaggg tggataataa aaatgtatct actaagcatg
    96121 attggcttcc agacatctct gatggaactc atactgtgga cttcactggt cttgataaaa
    96181 aattatctgt tgctttcaga ttttctccaa gacaaacttc gaatgttgtt tacgaatttt
    96241 ctaacataaa tataaaaaac attagtcctg catcagtgcc ggctattcct tcgaaagttt
    96301 tagagggaac cagcgtcttg tcgggtactg caatatcttc tggagataca ttagaaaaaa
    96361 gaaaatcgtt tgatggcgat atcctaagag tttataaaga tagcaaaatc attgctagaa
    96421 cagtaataaa aggcaataag tgggatgtta aactttcaaa gcctcttatt gcaggtgaaa
    96481 aattagattt tgagattttg catccgagat ctcaaaacgt tagtaaaaaa atttcaaaac
    96541 aagtcgaagc taaaccattt gatccagctt cctataaaga aaaagttata gccaaattaa
    96601 agccggttta tgaagctact agtgaaaaaa tcacaaatga tgcttggttg gatgaaaatg
    96661 cgaaggattt gcaaaaacaa aaattagaag aacaatatat ttctggaaaa gtagcgatat
    96721 cagaggctgg aactaaacaa gaagctatag atgcagcata taataaatat tcaagtcaaa
    96781 cagatccaga ctctcttcct agtcagtata aacaaggtaa taaagaaaat gaacaagaaa
    96841 aagggcgtca agatttaatc cagactcgtg atctgacgtt gaaagccatt caagaagaca
    96901 aatggctaac agagcaggag aaaacaattc aaaaagaaga agcattaaaa gcttttgaaa
    96961 ctggtataga aagtgttaat caaacagtat cattagaaca gttgaagcaa cggttaatag
    97021 tgtataaagc ttctgaaaaa gattcagaga aaaaagaata tcctgagtca attcctaatc
    97081 agcatattcc agggaaagaa aaagaagtta aagctgctaa acaagaagaa cttaaaaaat
    97141 tacatgacac aactcttgaa aaaatcaatc aagataaatg gttgacgcca gaccaacaag
    97201 ctgaacagtt aaaacaagcg gaagttactt ttaaaaaagg ccaagaagca attaaaagtg
    97261 ctcagacttt aactcagctt gagacagact tagctgatta tgtttctgag aatgaaggta
    97321 agggaaattc tattcccgat aaatacaaat ctggccataa agatgatttg gtaaataagg
    97381 ctgaagttaa acttaaggaa gctcacgaag ctactaaaca agcaattgaa aaagatccat
    97441 ggttgagtcc ggaacagaaa aaagctcaaa aagaaaaagc caaagcaaga ctagatgagg
    97501 gcttgaaagc tcttaaagct gcagatagtt tagagattct taaagtgaca gaagaagctt
    97561 tcgttgataa agaaaaaaat ccagattcaa ttccaaatca acataaagct ggaactgctg
    97621 atcaagctag aaaacaagct ttagatagtt tagataagga ggttcaaaaa gagttagagt
    97681 caattgataa cgataatact ctaacaactg atgagaaagc agctgctaag aaaaaagtca
    97741 atgacgctta tgatgtagct aagcaaacag ctatggaagc caattcttat gaagatttga
    97801 ctactattaa agatgagttc ttatctaatt tacctcataa acaaggaacg ccgcttaaag
    97861 atcaacaatc tgatgctatt gcagaattag agaagaagca gcaagaaatt gaaaaagcta
    97921 ttgagggtga taaaacatta ccaagagacg aaaaagagaa acaaattgct gactctaagg
    97981 aacgcttaaa atctgacacg caaaaagtta aagatgctaa aaatgctgat gctattaaaa
    98041 aagcatttga agaagggaaa gtgaatattc ctcaagcaca tatcccaggt gatttgaaca
    98101 aggataaaga aaaacttctt gcagaattga agcaaaaagc agatgatact gaaaaagcta
    98161 ttgatgttga taaaactctg acagaagatg agaaaaaaga gcaaaaagtc aaaacaaaag
    98221 ctgaacttga aaaagctaaa actgatgtta aaaatactca gacacgtgaa gaactagata
    98281 aaaaagttcc agaacttaag aaagctattg aagacactca cgttaaaggt aatcttgaag
    98341 gtgttaagaa taaggctatt gaagatctta aaaaagctca tactgaaaca gttgctaaaa
    98401 taaatggtga tgataccctt gacaaagcta ctaaagaagc tcaagtgaaa gaagctgaca
    98461 aagctttggc agcaggtaaa gatgcgatca ctaaagcaga tgatgctgat aaagtaagta
    98521 cagctgttac agagcacaca ccaaaaatta aagcagcaca taaaactggt gaccttaaaa
    98581 aagctcaagt agatgctaac acagctcttg acaaagcagc tgaaaaagaa cgtggagaaa
    98641 tcaataaaga tgctacacta acgacagaag ataaagcaaa acaactgaaa gaagttgaga
    98701 cagctcttac taaagctaaa gataacgtga aagctgctaa gacagcagac gctatcaatg
    98761 acgcacgtga taaaggcgta gcaacaattg atgccgtcca taaagcaggt caagacttag
    98821 gtgctcgtaa gtcaggtcaa gtcgctaaac ttgaagaagc agctaaagca acgaaagaca
    98881 agatttcagc tgatccaact ttgacaagca aagaaaaaga agagcaatct aaagctgttg
    98941 acgctgaact taagaaagcg atagaagctg ttaacgcagc tgacacagct gacaaggttg
    99001 acgatgctct tggtgaaggt gttacagaca tcaagaacca acacaagtca ggtgactcta
    99061 tcgacgctcg tcgtgaggct catggtaagg aacttgatag agtcgctcaa gaaactaaag
    99121 gtgcgattga aaaagaccct actttgacga ctgaagaaaa agctaaacaa gttaaagacg
    99181 tagatgccgc taaagaaaga ggcatggcta agcttaatga agctaaagat gctgatgctt
    99241 tagacaaagc ttacggtgaa ggtgttacag acatcaagaa ccaacacaag tcaggtgacc
    99301 ctgtcgacgc tcgtcgtgga ttacacaaca agtcaatcga cgaagtggcg caagcaacta
    99361 aggacgctat cacagcagat acgactttga ctgaagctga aaaagaaaca caacgtggca
    99421 atgttgataa agaagcaact aaagctaaag aagaacttgc taaggctaaa gatgctgatg
    99481 ctttagacaa agcgtacggt gacggtgtaa ccagcatcaa gaaccaacac aagtcaggta
    99541 aaggtcttga cgttcgtaaa gatgagcaca agaaagctct tgaagctgtt gctaaacgtg
    99601 tcactgctga aattgaggct gatccaacct taacaccaga agtgagagaa caacaaaaag
    99661 cagaggttca aaaagagctt gaacttgcga ctgataagat tgctgaagct aaagatgcag
    99721 atgaagcaga caaagcttac ggtgacggtg tcacagcgat cgaaaatgcc cacgttattg
    99781 gtaaaggtat cgaagctcgt aaagaccttg ctaagaaaga ccttgctgaa gctgctgcta
    99841 agacaaaagc tctcattatt gaagacaaaa cgcttactga tgatcaacgt aaagaacagt
    99901 tattaggtgt tgatacagag tatgctaaag gtatcgagaa tattgatgca gctaaggatg
    99961 ctgcaggtgt tgataaagca tatagtgacg gtgttcgtga catcctggca cagtacaaag
   100021 aaggtcaaaa ccttaatgat cgtcgtaatg ctgccaaaga atttcttctt aaagaagcag
   100081 acaaagtgac gaaactaatc aatgatgatc caaccttgac tcatgaccaa aaagttgatc
   100141 aaatcaacaa agttgaacaa gctaagttag acgcaatcaa gtctgttgat gatgctcaaa
   100201 cagctgatgc tatcaatgat gctcttggta agggtattga aaacatcaac aaccaatacc
   100261 aacatggcga tggcgttgat gttcgtaaag cgactgccaa aggcgatctt gaaaaagaag
   100321 ctgctaaagt gaaagctctt attgctaagg atccgacctt aactcaagct gataaagaca
   100381 aacaaacagc agcggttgac gcagctaaga atacagcaat tgcagcggtt gataaagcga
   100441 caacagctga aggcattaac caagaacttg gtaaaggcat cacagctatc aataaagctt
   100501 accgtccagg tgaaggtgtt aaagcacgta aagaagccgc taaagctgat cttgaaaaag
   100561 aagctgctaa agtgaaagct cttattacta acgacccaac cttaacaaaa gctgataaag
   100621 ctaaacaaac agaagctgtt gctaaagccc ttaaagctgc tatcgcagcg gttgataaag
   100681 cgacaacagc tgaaggcatt aaccaagaac ttggtaaagg catcacagct atcaataaag
   100741 cttaccgtcc aggtgaaggt gttaaagcac gtaaagaagc cgctaaggct gatcttgaaa
   100801 gagaagctgc taaggttcgt gaagctatcg ctaacgaccc aaccttaaca aaagctgata
   100861 aagctaaaca aacagaagct gttgctaaag ctcttaaagc tgctatcgca gcggttgata
   100921 aagcgacaac agctgaaggc attaaccaag aacttggtaa aggcatcaca gctatcaaca
   100981 aagcttaccg tccaggtgaa ggtgttgaag cacataaaga agctgctaaa gctaatcttg
   101041 aaaaagtagc taaagaaact aaagctctta tttcaggaga ccgttacttg agcgaaactg
   101101 aaaaagcagt ccaaaaacaa gctgttgagc aagctcttgc gaaagcactt ggtcaagttg
   101161 aggctgctaa gacagttgaa gctgttaagt tggcagaaaa ccttggtact gtagctatcc
   101221 gttcagcata tgttgctggt ttagctaaag atactgatca agcaacagct gctcttaacg
   101281 aagcgaaaca agctgctatt gaagctctta aacaagctgc ggcagaaaca cttgctaaga
   101341 ttacaactga tgctaaattg actgaagctc aaaaagctga acaatcagaa aatgtatcat
   101401 tagcgcttaa gacggctatt gcgactgttc gttcagcaca atctattgcg tctgtgaaag
   101461 aagcaaaaga taaaggtatt actgctatcc gtgcagccta tgtgcctaat aaggcagtcg
   101521 caaaatcatc gtcagcgaac catcttccaa aatcaggtga tgcaaactca attgttcttg
   101581 ttggcttagg agttatgtct cttcttttag gtatggtgct ttatagcaag aaaaaagaaa
   101641 gtaaagacta agaacctggc tttatccaaa ttgctttcta ctatattttc aaaccaaggt
   101701 gattttgaaa tcaccttggt tttttggatc gtaagggccc aagaacggag tgtattgaaa
   101761 acatttcaaa gttcaattga aaaggcaaca gttttctgta cagaatttat aaggcgtttt
   101821 ttgttcaaac gatgactcat ttagttatgg gtgtttgata attaagatta ctgtgaaggt
   101881 gatggtagtt ccaccagtgg acttcctcct tggttttaag ggttaattgt tctagtgaat
   101941 aaaaggtttc ttggtcgcgc agtagggatc aagcgagcag ataaaatgcc tattttaaat
   102001 cagttcgagc gaattttcgt gctacaagct caaaagaggc tactaaagta ttagaatagt
   102061 ttatctctga gtgaagttct tgttataaga agatgatgtt atcgtttgaa acgaccaaaa
   102121 aatctcctaa cttttactaa tttctacatg aaatctagtc cagtatttac tctacaacct
   102181 tgattgattc gcttaataaa gacatttcta cttgat
//
LOCUS       DAUGQX010000002        57331 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUGQX010000002 DAUGQX010000000
VERSION     DAUGQX010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57331
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.002"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            114..275
                     /gene="sagA"
                     /locus_tag="VIA51_000089"
     CDS             114..275
                     /gene="sagA"
                     /locus_tag="VIA51_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEQ8682069.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            497..1447
                     /gene="sagB"
                     /locus_tag="VIA51_000090"
     CDS             497..1447
                     /gene="sagB"
                     /locus_tag="VIA51_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEQ8682070.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1444..2502
                     /locus_tag="VIA51_000091"
     CDS             1444..2502
                     /locus_tag="VIA51_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEQ8682071.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNDPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSDALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQVLPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2522..3880
                     /locus_tag="VIA51_000092"
     CDS             2522..3880
                     /locus_tag="VIA51_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEQ8682072.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3855..4526
                     /locus_tag="VIA51_000093"
     CDS             3855..4526
                     /locus_tag="VIA51_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8682073.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4523..5206
                     /locus_tag="VIA51_000094"
     CDS             4523..5206
                     /locus_tag="VIA51_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEQ8682074.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLVALSYQDFLDV
                     LLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGTVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5229..6152
                     /locus_tag="VIA51_000095"
     CDS             5229..6152
                     /locus_tag="VIA51_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682075.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6161..7288
                     /locus_tag="VIA51_000096"
     CDS             6161..7288
                     /locus_tag="VIA51_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682076.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLETKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSFLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            7285..8403
                     /locus_tag="VIA51_000097"
     CDS             7285..8403
                     /locus_tag="VIA51_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682077.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALISFSSLLLKPTKL"
     gene            8974..11706
                     /locus_tag="VIA51_000098"
     CDS             8974..11706
                     /locus_tag="VIA51_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEQ8682078.1"
                     /translation="MINKKCIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERPYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGCVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      11871..11986
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            11984..12484
                     /locus_tag="VIA51_000099"
     CDS             11984..12484
                     /locus_tag="VIA51_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEQ8682079.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12678..14636
                     /gene="ligA"
                     /locus_tag="VIA51_000100"
     CDS             12678..14636
                     /gene="ligA"
                     /locus_tag="VIA51_000100"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEQ8682080.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPYQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            14650..15672
                     /locus_tag="VIA51_000101"
     CDS             14650..15672
                     /locus_tag="VIA51_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8682081.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     GQELEE"
     gene            16065..16262
                     /locus_tag="VIA51_000102"
     CDS             16065..16262
                     /locus_tag="VIA51_000102"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEQ8682082.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16297..17013
                     /gene="atpB"
                     /locus_tag="VIA51_000103"
     CDS             16297..17013
                     /gene="atpB"
                     /locus_tag="VIA51_000103"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEQ8682083.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17031..17525
                     /gene="atpF"
                     /locus_tag="VIA51_000104"
     CDS             17031..17525
                     /gene="atpF"
                     /locus_tag="VIA51_000104"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEQ8682084.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRLQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17525..18061
                     /locus_tag="VIA51_000105"
     CDS             17525..18061
                     /locus_tag="VIA51_000105"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEQ8682085.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDVLQADVLAILETFVTTN
                     LDQSLSSQAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18077..19585
                     /locus_tag="VIA51_000106"
     CDS             18077..19585
                     /locus_tag="VIA51_000106"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEQ8682086.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19601..20476
                     /locus_tag="VIA51_000107"
     CDS             19601..20476
                     /locus_tag="VIA51_000107"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEQ8682087.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20638..22044
                     /gene="atpD"
                     /locus_tag="VIA51_000108"
     CDS             20638..22044
                     /gene="atpD"
                     /locus_tag="VIA51_000108"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEQ8682088.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVADTVRGFKEILEGKYDELPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22057..22473
                     /locus_tag="VIA51_000109"
     CDS             22057..22473
                     /locus_tag="VIA51_000109"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEQ8682089.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22739..22996
                     /locus_tag="VIA51_000110"
     CDS             22739..22996
                     /locus_tag="VIA51_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEQ8682090.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23061..24332
                     /gene="murA"
                     /locus_tag="VIA51_000111"
     CDS             23061..24332
                     /gene="murA"
                     /locus_tag="VIA51_000111"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8682091.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24336..24524
                     /locus_tag="VIA51_000112"
     CDS             24336..24524
                     /locus_tag="VIA51_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8682092.1"
                     /translation="MTNGLKYVLEQMLLLFIIAALACLFLAIGLMIGYSFMGDGQSPW
                     HILSMDKWAELVNKFTGK"
     gene            24560..25099
                     /locus_tag="VIA51_000113"
     CDS             24560..25099
                     /locus_tag="VIA51_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEQ8682093.1"
                     /translation="MLTRKKRKRVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFK
                     PAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKP
                     YLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVP
                     NVQAGLTVDYRTGQIAINL"
     gene            25382..26425
                     /gene="pheS"
                     /locus_tag="VIA51_000114"
     CDS             25382..26425
                     /gene="pheS"
                     /locus_tag="VIA51_000114"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8682094.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGDERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            26635..29040
                     /locus_tag="VIA51_000115"
     CDS             26635..29040
                     /locus_tag="VIA51_000115"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEQ8682095.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPADGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGNLDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTSIKLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            29150..29527
                     /locus_tag="VIA51_000116"
     CDS             29150..29527
                     /locus_tag="VIA51_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEQ8682096.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            29520..29906
                     /locus_tag="VIA51_000117"
     CDS             29520..29906
                     /locus_tag="VIA51_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEQ8682097.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            29979..31055
                     /locus_tag="VIA51_000118"
     CDS             29979..31055
                     /locus_tag="VIA51_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682098.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GISNKTITTAVLMQTFFLSFLGSGLGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMI
                     CFALLGTLFSVFNIIRIDPLKAIG"
     gene            31065..31733
                     /locus_tag="VIA51_000119"
     CDS             31065..31733
                     /locus_tag="VIA51_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682099.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYRMQDGEL
                     CQER"
     gene            complement(31835..32752)
                     /locus_tag="VIA51_000120"
     CDS             complement(31835..32752)
                     /locus_tag="VIA51_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEQ8682100.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQSDYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRTVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            32903..36118
                     /gene="rexB"
                     /locus_tag="VIA51_000121"
     CDS             32903..36118
                     /gene="rexB"
                     /locus_tag="VIA51_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEQ8682101.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKSDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVSTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQE
                     KNFQLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLMTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            36079..39747
                     /gene="addA"
                     /locus_tag="VIA51_000122"
     CDS             36079..39747
                     /gene="addA"
                     /locus_tag="VIA51_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEQ8682102.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCRDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFNEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFSLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVATPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEEMRLLYVAMTRAEKKVYFIGKASKSKSQE
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKLDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            39887..40699
                     /locus_tag="VIA51_000123"
     CDS             39887..40699
                     /locus_tag="VIA51_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8682103.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLEAPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            40840..41016
                     /locus_tag="VIA51_000124"
     CDS             40840..41016
                     /locus_tag="VIA51_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEQ8682104.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(41144..41506)
                     /gene="mscL"
                     /locus_tag="VIA51_000125"
     CDS             complement(41144..41506)
                     /gene="mscL"
                     /locus_tag="VIA51_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEQ8682105.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            41637..43451
                     /gene="dnaG"
                     /locus_tag="VIA51_000126"
     CDS             41637..43451
                     /gene="dnaG"
                     /locus_tag="VIA51_000126"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8682106.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFHLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKISDLLPNFDYFQVEQSVNALRIQDRQK
                     HQGQIAQAVSNLVTLPMPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     ELLYQRLKQQGHITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            43460..44569
                     /gene="rpoD"
                     /locus_tag="VIA51_000127"
     CDS             43460..44569
                     /gene="rpoD"
                     /locus_tag="VIA51_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEQ8682107.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLTEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            44805..45143
                     /locus_tag="VIA51_000128"
     CDS             44805..45143
                     /locus_tag="VIA51_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEQ8682108.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            45281..46135
                     /gene="rfbD"
                     /locus_tag="VIA51_000129"
     CDS             45281..46135
                     /gene="rfbD"
                     /locus_tag="VIA51_000129"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEQ8682109.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDHPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            46254..47408
                     /locus_tag="VIA51_000130"
     CDS             46254..47408
                     /locus_tag="VIA51_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEQ8682110.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSRPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLATADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTK
                     QKGQLAELINQVDAGFDSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            47398..48330
                     /locus_tag="VIA51_000131"
     CDS             47398..48330
                     /locus_tag="VIA51_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8682111.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAVCHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASAIGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            48333..49136
                     /locus_tag="VIA51_000132"
     CDS             48333..49136
                     /locus_tag="VIA51_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682112.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            49136..50341
                     /locus_tag="VIA51_000133"
     CDS             49136..50341
                     /locus_tag="VIA51_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682113.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            50366..51373
                     /locus_tag="VIA51_000134"
     CDS             50366..51373
                     /locus_tag="VIA51_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8682114.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTIYRMTTDSDSR
                     PTDTPKMIYRIQKLLDTQLNYLKKYNQVDTKEVSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            51370..53115
                     /locus_tag="VIA51_000135"
     CDS             51370..53115
                     /locus_tag="VIA51_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEQ8682115.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLIIMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDTKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFENWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGDSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            53112..55586
                     /locus_tag="VIA51_000136"
     CDS             53112..55586
                     /locus_tag="VIA51_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8682116.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYAHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            55765..56460
                     /locus_tag="VIA51_000137"
     CDS             55765..56460
                     /locus_tag="VIA51_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8682117.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            56462..56803
                     /locus_tag="VIA51_000138"
     CDS             56462..56803
                     /locus_tag="VIA51_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEQ8682118.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            56796..>57331
                     /locus_tag="VIA51_000139"
     CDS             56796..>57331
                     /locus_tag="VIA51_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ8682119.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVSLV"
BASE COUNT        18263 a         9587 c        11469 g        18012 t
ORIGIN      
        1 agtacaattg agctagcctt gtccttgttg tgttaacttt atttttaaaa taaggttaaa
       61 aataaacgac tcgcgttctt atcagttact tattagataa ggaggtaaac cttatgttaa
      121 aatttacttc aaatatttta gctactagtg tagctgaaac aactcaagtt gctcctggag
      181 gctgctgttg ctgctgtact acttgttgct tctcgattgc tactggaagt ggtaattctc
      241 aaggtggtag cggaagttat acgccaggta aataatctat ttagcatctc tatgtgatag
      301 tgatattaag gtaatgagtt tgctagcaac taagttatct ttggtaactt ctgattatag
      361 atgaatggca tagaggtgtt agaaaacatg agacaaaagt aatcttcttg atgctaacgt
      421 ctcaggtaat tagcaggtac tagatagtac ctgctaatta ctatatgttt agtaaaatga
      481 gataggaaag atagttatgt cattttttac aaaggaacaa caacctaaag agaattgtcc
      541 gccaataact gttgaaaaag caaggcaatt gtttgaattt aatacaaacc acttgtcctt
      601 atcggattac catcatcaaa cggtgctaaa aacgtcaaag cagctagttg ctcaacattt
      661 aatgcctaat gcaaccgata atcttagtca acattttttg atgaactata aagctaataa
      721 taattattta ggcttccaag ctagtattgt cgactttttt acagattctg ccgttgctaa
      781 tttttcaagt agttacgttt atgaaagtca ggaaaagata attcgtttac caaaacctac
      841 caagatatca actgctctgt cgacatgtat tataaaacga agaagtcatc gtcaattttc
      901 agatagacaa atgcctcttc aagatttatc aaacattctt tattatgcat gtggtgttag
      961 ttcacaagca tcaattagag atggagcatc agataagatt acactcagaa actgtgcttc
     1021 aggtggaggt ttatacccta ttcatttagt tttttatgct agaaacatca gtaaattaat
     1081 agatggtttc tatgaatatc taccctatca gcatgcacta aggtgttatc ggcatagctc
     1141 tgaggaaaac gttagagatt ttgcggaata cggtgctatt aatgctgaaa attgtaatat
     1201 tattattatt tatgtctacc attacatgaa aaatacacgt aaatatggga atcaggcgac
     1261 tgcctatgct tttattgaat caggagaaat agcccagaat attcaattga ctgcaactgc
     1321 cttaacttat ggaagtattg atattggtgg ttataataag gaatatctcc aagaattatt
     1381 agatttagat gggctaggag agcatgtgat tcacatgaca ctcgtaggaa ctaaggagtc
     1441 tcaatgaaat atcaacttaa tagtaatgtt cgtgtcgtga catttcaaga tacattttgt
     1501 tttagaaaag gaatctggga ctttaatgaa gccattctag atttgacaca agaacctcaa
     1561 aatttaaaga tagtttatca agaaatagtt tcacagttgg ttaagggagt agccattgat
     1621 actgaaactt atgaaaatac tttagaacct gagacgttcg ctaatttaat ggaagtcatt
     1681 tcaggcttgt attacaatga tatgctgatg cttgaggatg actacaatct tgaagaaaat
     1741 gtcatgaaaa ttttaatggg taatttccgt tttatggcgc aagcaggtca tatggtaagc
     1801 aatgatcctg ttttgtttat cagtgattcg acttatgtta atgaatctgc tgagttgcta
     1861 gctgaacaac tgcatttaca attgcaagtg gctagtgatg acttaaaaat gttaattcag
     1921 cagacagatg ttagttcgcg tttagatgct ttggagcatc gccgtaacat gaattgttta
     1981 tcagatgcct tgtgcgatta ccaaagtatt attatttgtc aagaacgctt gaatattatg
     2041 atgttgcgac acttgaatga agttagcgta gctatgaaaa aacaattagt gattggtttt
     2101 gtagatggac cattcttgca cacttgtact ttgaatcctc cccatagtgc tgactttgat
     2161 agcttagaaa gaagagtttt ggcacgttta caagactcaa ctctctatca acattttgct
     2221 aatcaggttt taccagccac acaagatgtg agccaggcct atttaccatt gttaaatgtt
     2281 ttaatgaatt tagtcgttag cgaagctttc attattgctc aaacaggtag ttctaaattt
     2341 gagggacgtt tattaagcat ttacttaccg acgcttgaga ttcaggtcca agatattttg
     2401 aaaatgtcta attcacagac acaaggagct ttggcaaaat taaagtatga ggatcagcag
     2461 atatcaacac gtgagattgt taaaaaactc cttgacgagt aacctataag gagaatctat
     2521 tatgttatac tattatcctt cttttaatca tatttttgat gaattaaaaa gtttaagtgg
     2581 caatcgaaca ggtatcttaa atcaatctca agttccagtt tgcaaccatc ctcacgatgt
     2641 ttacttaaaa agtattactg gccaaatgcc agattatcat aaacaattta taggtgagtt
     2701 gagtcaagtt agttatcaca ttattggtta cggcagttac tatgaagaag cacttatcaa
     2761 gtatttagga gaaagtattg aacgctatgc tactgtaatt gccggagact tactatcaga
     2821 tcggattgtc tatgcttctt ataatgagtt aaaactgtta cataaagtga tgcctttaga
     2881 atacttgcaa gtgtttaccc aagaacagat cgcattatct tgtgacttgc aaatgatgat
     2941 gtgcgataaa atggtaactg agaacgatgt attgggctgg gttaaatgtc ccatgttctt
     3001 tgaggacgca gagatgtatg ttccagctca aatgctttgt gttgggtata aaacaaatga
     3061 gactgtagga gaaagacgga taataccagg attttctacg ggaacagctt ctcacaaaac
     3121 gttagaagcg gctatgtgca acagtttgat tgaatacatc cagatcgatt caatgatgct
     3181 tagctggtat actaagaagc cttgccccaa gattattgtt gatgatcctg atattgaagt
     3241 gattttagaa gaagctagac tgggaaaaga cagtctatac gacattattc ctattgatat
     3301 gactgtagga gaagataatc ctctttatac gtttggaatc attctcaaaa ataaatatga
     3361 tgaagggcct tacctcttgt ttggagtgca ggctgggtta gatcctaaac atgctttgct
     3421 aagagggatc atggaagctt cagctattag ctatagttac tactataatc ttttatatca
     3481 aaaagcttcc cttgcaaata ttgaatgcga agaacctttg tttttagatt tagatagtaa
     3541 tgtcttctat tatgcacatc ccaaggacca agaccataaa tggaaggcct ttgaaccttt
     3601 gatttcagga gaagttctgt taagtgattt ggaagatcat tctggtaaag ataaaaaaga
     3661 agatttgaag actttattag cttatgctaa gaaagtcagt cctaatgctg tctttttaga
     3721 tattacacct cctgaagctc tagaaaaagg ctggtacgtc acgcgagttc tgatgccaga
     3781 acttcttgaa atgtgtatac cagcatttcc ttttgctaat catccacgaa tgagacagtt
     3841 tggaggtgta acaaatgcct ttgtccatcc aatgccttaa tctttgtttt ttgttggtaa
     3901 ctttttgtcc ttcaattcct atgcaagcta tttttggaaa ggaagatagt ggttatgcat
     3961 ttaatttaat tggttttcta agagcaactc tgatttatga cattttggct ttggtaagta
     4021 tttatgtttt gtcacctcaa ataaccttgt ctcttgaaag tattgatagt aagacgttct
     4081 ttatgggact tgtattttgc gtcttgatag tactgattga actcgttttc ttacatggtt
     4141 tacgttgttg gcaaaaaaag caatggcttc ctgcaacttt ctcgtttgta ggaacgacaa
     4201 atgattggtc taagattggc tatcctttat tactagcttt atttgaagag acgatttatc
     4261 gttttttgtg gtttaatata ttagcttttc aatggcattt accaacaatt attgttttaa
     4321 ttgtaactag tttttgctat gctttaaatc acttattgat ggggaaatcc attttttatg
     4381 ctaagttggt aacaggcatc atttatggta gtatttacat gctgactagt caattgtggt
     4441 tggttgtgat aatgcatgta ggaggtaact tgctagttga gtgtcttagc catcttcaaa
     4501 caaaaaagaa gaaggaggtg acatgatgct attggttttg ctgtcgtttt taggtctaac
     4561 tactctttgg ttgaccagtt atcgaagacg ttgtttggct agatggcatc ttcaatggtt
     4621 agtggcctta tcctatcaag attttttaga tgtcttactg agtctgtttc aatttgtcgt
     4681 tattatactt gttttattct tttactcagc tactattaat ctaggagagg ttctgacctt
     4741 tttgacacaa actagctggc attggcagat tctttgttat ttagtgttat atcttatggc
     4801 catcatagag atgacgcttt tagttttaat tcttatcttt gatgttttgc tccagaaaga
     4861 cagtcgattg ctctttaaaa aaataacttg gctgcctttt agacaagata aaccagtctt
     4921 aagtatactt ttactaggca cagttattct agtagacagt ctcttttatt tgggcttgct
     4981 tatattatta ggagaacagt cgctaacaag tttagcaacg cttattttag gttatgggat
     5041 agtcaaggct tgtcgctatt caggttggtt aaatgtacta ttagcttttt gtcttttcac
     5101 tatagttgga ctatgggcag ttacggcaac tttattatat ggttggctag taggtgcgat
     5161 gatattaacg gtgacttatt tgatgattag ttgcaaagag tattagcaat attaaaaagg
     5221 agtgatatat gagttttgta caattaacaa atgttgtcaa gtcctacaaa aacggcaaga
     5281 aagctgtcaa tgatgtttcc ttgtctattg aagcaggtaa tatttatggt ttgttaggac
     5341 caaatggtgc tggtaagtct accttgatta atcttatctt aggcttgatc cctttgagtt
     5401 ccggtaaaat tactgtttta gggcaatccc aaaagactat tcgaaaaata agttcgcaga
     5461 taggttatgt tcctcaagac attgctgttt atccagacct aactgcttat gaaaatgtag
     5521 aactatttgg gtcactttat ggcttaaagg gagctcagct taaaaaacaa gttctaaaaa
     5581 gtttagaatt tgtggggcta cactcccaag ctaagcagtt tccaagtcaa ttctcaggag
     5641 gaatgaagag acggttaaat atcgcttgtg cgctagttca ttcacctaaa ttaatcattt
     5701 ttgacgaacc gactgtaggg attgatcctc aatcacgtaa tcatatttta gagtcgattc
     5761 gtttgctaaa caaagaaggt gctacagtta tttatacgac ccattatatg gaagaagtag
     5821 aggctctttg tgattatatt tttattatgg atcatggtca agttattgaa gaaggaccta
     5881 aatttgaact ggaaaaacgt tacgttgcaa atctagcaaa ccagattatt gtaactctaa
     5941 cagattcacg tcatttggaa ctggcagata agcctgattg gtctttgata gaagatggag
     6001 aaaaactcat gttgaagatt gataatagtg atatgacatc agttgttcat cagctcacac
     6061 aggccaatat tacttttagc gagattagac ataaccattt gaatttagaa gaaattttct
     6121 tacacttaac aggtaagaag ttacgagatt agaggttact atggttttat ttcatttaat
     6181 caaaaaagaa agtttacaga tttttagaaa ccgaacagcc ttattgatga tggtgatttt
     6241 tccaattttg atgatcgtta ttttaagttt tgcctttaaa tcaagtttta atactgcgac
     6301 aacagtccct aaattgacca ttcgttacca attagagggt gaaaaaacgg attaccagaa
     6361 aaattttctt gcttttttaa aagttttaaa ccaaaaactt catttagaga ctaaacctag
     6421 taattctctt gaaaaagatc gacaaagggt cagtgaagga gccttaacgg ctgttttaga
     6481 agtgaagaag aatcagacca ttaaggttat tactaataat attaatcagc aaaatgcaga
     6541 tttgatcaat atgctagtaa aaaattatgt tgataatgct aaaacttatg actcgatagc
     6601 agctctttat cctcaacaat taaatcatat cagaaagcga agtgtggact atgttaaggt
     6661 cagttcaata cagacaagta aaggaatgac atcagctgat tattatgcta tttccatgtt
     6721 taccatgatt actttttata gtatgatgtc tgcgatgaac cttgttttgt cagatcgtca
     6781 acaacggatt acaaatcgta ttcacttaac aggagtttct ccaagttttt tggtctttgg
     6841 gaaattaata ggtgctatgt tagcaacaac tgttcaattg agtcttttat acatttttac
     6901 aaggtttgtt ttacgagtta attggggcac taatgagtgg atgcttattg gtataacagc
     6961 ctccttagtc tatctctctg tagctatagg tatcgggcta ggtataagca ttaaaaatga
     7021 ggctttttta acggttgcat ccaatactat tattcctata ttcgcctttt taggaggcag
     7081 ttacgttcca ttgacaacat tacacagctc tattattaat caattgtcga atatatctcc
     7141 tattaaatgg gttaatgata gtttgttcta tcttattttt ggtggtcaat ataatccgat
     7201 tcctgtaact ttgatcgtta atattagtat cggaacaatt tttataatat tggcattgat
     7261 aggtatgaga aagcaggtga cgacatgatt tgttttataa aaactctatt tgttaagata
     7321 aagcgcaaaa aaacaagtta tgtgacattc tttttaatgc ctattttaac gacacttttg
     7381 gctttatctt tgagtttttc aaataataat caagctaaaa ttgggatatt agataaagat
     7441 aatagtcaga tatctaaaca atttattgct caactaaagc aaaacaaaaa gtacgacatt
     7501 tttaccaaaa tcaaaaaaga gcatattgat cactaccttc aagataaatc tctagaagcg
     7561 gtattgacta ttgacaaagg gttctcagat aaagtgttgc aaggaaaatc tcaaaaactc
     7621 aatatacgtt cgattgctaa tagcgaaatt acagagtggg taaaggcaca gaccaattat
     7681 ctattggaaa attataatat tataggggat gtggctctag gtaacgaaga tacttttaat
     7741 agaattctcc aaaaaaacca acagttaaat tatgatgtta agcaagtaac tttgacagac
     7801 cgatcacgta gcaaagcagt atcttccaca acgacaggat ttttgcttat tctaatgtta
     7861 ggtagtacga gcgtgattta cagtggtatt ttggcagata aatctagtca gttataccat
     7921 cgattaatgt tatcgaactt atctcgtttt cgctatatgt tgagttacgt ctgtgtagga
     7981 tttgttgctt ttacgattca aattgtcatt atgctgagtt tgttaaaagt atttaatatt
     8041 agtttttttg ttccgacatc acttcttttg attatttttt tcctttttag tttattagcg
     8101 ataggctttg gcctgctgat tggagctatc acacaaaatt cccaacaaag tagccagtta
     8161 gctaatctta ttgtaatgcc gacttcaatg ttggctggct gtttatggcc attgtctatt
     8221 acgccttctt atatgcaagc aattggtaag ttattaccac aaaattgggt tttatcagcc
     8281 atagctattt ttcaaagtgg agggacctta tctcaggctt ggccatactt gttagctcta
     8341 atgggaacag cactagcttt gattagtttt tcaagtttat tattaaaacc taccaaacta
     8401 taattagtct tttgttaaaa aatactttcc taattagcta actaccaggt agccctttta
     8461 ttggcttata tgcaataaaa gggttgcttt ttgcttatat tttctctagt gcacttatct
     8521 tttgttaaaa gtgattgcga tgttactgtt gttactgtgt tttttagaga gcatattatc
     8581 aaaagcgacc cctctataaa gttcgttttt gttgataaat gggttgtcaa agtattttaa
     8641 aaaacgtttt caataaacat aaaaactaat gttattaaaa aaagttttga aaacgtattt
     8701 attttatggg atgtttttgt tacaataagc atgtatcgaa tgctataaag ctgtcttgtt
     8761 cgctatcagg ggtgcttgtg atgttatgtc agatcaaaca agtctttaat tgggtgactt
     8821 aacagattaa aagaaaagat ctaatcgtgt tacttgatag tataattaat gcaaacagaa
     8881 agtgtatccc aattcatagt ctcaggtgga ggttaatatt caaaaataaa atcttgttgt
     8941 tgtcttaaac taatcacatt aaaaggagat atcatgatta acaagaaatg tataatacct
     9001 gtttcattgt tgacactagc tattacgctt actagtgttg aagaagttac ttcacgccaa
     9061 aatttgactt atgccaatga aatcgtaaca caaaggccaa agagagaatc tgttattagt
     9121 gataaatcga attttcccgt catatcacct tacctagcaa gtgtggattt tggtgagaga
     9181 aaaacacctt tgccaacacc tgataaagga gtaaaagtaa ctactgaaca gtctattgct
     9241 caagtaagaa aggggcctga agaaagaccc tatactgtta ctggcaagat tacgagtgtg
     9301 atcaatggct ggggaggcta tggcttttat attcaagata gtgaaggtat tggactttat
     9361 gtttatcctc aaaaagattt aggatacagt aagggagata ttgttcaatt aacaggtaca
     9421 cttactcgct ttaaaggtga tttacaactc caacaggtga ctgcacacaa aaagttagag
     9481 ttatcttttc cgacttctgt taaagaagca gtaatatcag aattagaaac aacaacaccc
     9541 tcaacattag ttaagttatc tcacgtgaca gttggagaat tatcaactga tcaatataac
     9601 aacacatctt tccttgtaag ggatgatagt ggtaaaagta tagttgttca tatagatcat
     9661 cgtacagggg ttaaaggggc tgatgttgtt actaaaataa gtcagggtga tttgattaac
     9721 ctcacagcca tattgtctat tgttgatggt caattacaat taagaccgtt ttctcttgaa
     9781 caattggaag tggttaaaaa ggtcacaagc tcaaatagtg atgcttcatc tcgtaatatt
     9841 gtgaaaatag gcgagattca aggagctagt catacgtcgc cacttctcaa aaaagcggtc
     9901 accgtagaac aggttgttgt cacttattta gacgattcca ctcattttta tgttcaagat
     9961 cttaatggtg atggtgattt agcgacttca gatggtattc gtgtttttgc taaaaacgct
    10021 aaggttcaag tcggcgatgt tttgaccatt tcaggtgaag tggaagaatt ctttggtcgt
    10081 ggttatgagg aacgtaagca gactgacctt accatcaccc aaattgtggc taaagcagtg
    10141 accaaaacag ggacagctca agttccatca ccgcttgttt tagggaaaga tcgtatcgcg
    10201 ccagccaata ttattgataa tgatggcttg cgtgtgtttg atccagaaga agacgctatt
    10261 gattattggg aatcaatgga aggcatgtta gtggcggttg atgatgctaa aatccttggt
    10321 ccaatgaaaa ataaagaaat ttatgtctta cctggctcta gtacaagacc gttaaataat
    10381 tcaggtggag tattacttcc agctaattct tataacacag atgtgattcc tgttcttttc
    10441 aaaaaaggca aacaaattat taaagcagga gactcttaca aaggaagatt agctgggcca
    10501 gtatcttata gctatggtaa ttacaaggtc tttgttgatg acagcaaaaa catgccaagt
    10561 ttaatggatg gtcatctaaa acctgaaaaa acaaacttgc aaaaagacct tagcaagtta
    10621 agcattgctt cttacaatat tgaaaacttc tcagccaatc cttcttcaac taaagatgag
    10681 aaggtcaaac ggattgccga atcctttatt catgatctga atgctccaga cattattgga
    10741 ttaattgaag tccaagataa taatgggccg actgatgatg ggacaacgga tgcgacacaa
    10801 agcgcgcaac gcctcattga tgctattaaa aaactaggtg gcccaactta tcgttatgtt
    10861 gatattgctc cagaaaataa tgttgacgga ggtcaaccag gtggtaatat tcgaacagga
    10921 ttcctttatc aaccagagcg cgtcagcctt tctgataagc caaaaggcgg tgctcgtgat
    10981 gctctaactt gggttaatgg agaattaaac cttagtgttg gtcgaattga tccaactaac
    11041 gccgcttgga aagatgttcg taaatcacta gcagcagaat ttatcttcca aggtcgtaaa
    11101 gtcgttgttg ttgcaaatca tttgaactct aagcgtgggg ataatgctct ttatggttgt
    11161 gtgcaaccag tcacttttaa atctgagcaa agacgtcacg tcttggctaa tatgctagca
    11221 caatttgcga aagaaggggc aaaacaccaa gctaatattg tgatgctagg tgactttaat
    11281 gattttgaat tcacaaagac gattcaatta atcgaagaag gtgacatggt taacttggtg
    11341 agccgacatg atatttcaga tcggtattct tattttcacc aaggcaataa tcagaccctt
    11401 gataatatat tagtttcacg ccatttactt gatcactacg aatttgacat ggttcatgtg
    11461 aattccccat ttatggaagc tcacggacgc gcatcagatc atgatccatt gttacttcaa
    11521 ttatcatttt ccaaagaaaa tgataaggca gagtcttcta aacaaagtgt aaaagctaaa
    11581 aaaacttcaa aaggaaaact gttgccaaaa acaggagata gtcttgttta tgtgataacg
    11641 ctactaggaa cggctagttt attagtgcct attttattat tgactaaagg caaaaaggaa
    11701 tcatagcgat ttgaagaatt gcagttcata aagagtcgtt aaaggtttga tatacttacg
    11761 ttagatctta agctaaaatg gatgactata taaaaactaa gattgataac aaaagaagat
    11821 aacaataaga cagctttact tgctaaagac ttttgtcaag ctaattgttt tatggtacaa
    11881 tgtaaccgtt gctttgcaac ccttggtgct tagttccctt tcaccaagca tattagaaac
    11941 gtagatagct tttgagagtt atccagacgt taaaggagaa aaaatgacaa aattgactgt
    12001 acacgactat gttcacattg ggctagtagc tgccttgtat gttgtcttaa ctattacccc
    12061 gcctttaaat gcgatttctt atgggatgta tcaatttaga atatctgaaa tgatgaattt
    12121 cttagctttt tatcatcgca agtatattat tgcggtgact cttggatgta tgattgctaa
    12181 cttttatagt ttcggactga ttgatgtctt tgtaggcggc ggttcaactc ttatttttgt
    12241 gaccttaggt gttattttgt ttagtaagta tcaaaaagat tatcttttta atggtatttt
    12301 taataaagct tttgtttact tttctttctt ttttgcaact tccatgttta ctgtagcaat
    12361 cgaactttac ttctttggag caccattttt attaacatgg tttacaactg cgttaggaga
    12421 attagtatct ctgctcatag gatcacttat tattgataag ttgtctcaaa gaatttcctt
    12481 ttagtaatgc atcatactca aaagagttgg gtcaataccc ttctcttttt tatgttgttt
    12541 gtaatgttaa aatcgttcta gatagaaata tttaacactt tagctaatag taccatatgg
    12601 agtggccaac gattactttt gatgttgtta tgatatagaa atagctcatt tgttatcttt
    12661 tatgataaaa taaaagtatg aaaaaacgca taaaagaatt aacagatctt cttaaccgtt
    12721 accgttatga ctattatact aaagatgccc catcagtttc tgacagtgac tatgataagc
    12781 tttatcgtga actggtgact ttagagcagt catatcccga gtatgtcttg caagatagcc
    12841 caacgcagca ggttggaggg actattttaa aggggtttga aaaatatcga catcagtatc
    12901 cgctttttag tttgcaggat gctttttcac gtgaggagct ggatgctttt gataagcgcg
    12961 tcaaggccga atttccgaat gccacctatc tagcagagtt aaaaattgat ggtttatcta
    13021 tttccttgag ttatgagaat ggcttcttac aggttggagc aacacggggt gatggcaata
    13081 tcggtgaaaa tatcacagaa aatatcaaaa aaataaagga tattccttac caattgagtg
    13141 agcctttaac catcaccgtt cgaggagagg cttacatgtc tcgtcagtcc tttaaagcga
    13201 tcaatgaagc acgccaagaa aatggggaga ctgaatttgc taatcctaga aatgctgccg
    13261 ctgggacact aaggcagcta gatacgtcag tggttgctaa gcgtcaacta gccacttttt
    13321 tgtatcaaga agctagtccg acagctagaa atcaacaaaa tgaggtctta gcagaattag
    13381 cagatctagg tttttcagta aatccgtatt atcaactcac atcgtctatg gatgagattt
    13441 gggattttat caaaactatt gaggcaaaaa gagatcaatt agcttatgac atagatggcg
    13501 ttgttattaa agttaatagc ctagccatgc aagaagagct agggtttacg gttaaagctc
    13561 cacgctgggc cattgcttac aaatttccag cagaagaaaa agaggcagaa atcctttcgg
    13621 ttgactggac agtgggacga acaggcgtgg tcacacctac agcgaatcta actcctgtgc
    13681 aactagcggg gacaaccgtg agtcgtgcaa ccctacataa tgtggattat attgccgaaa
    13741 aagatatccg tattggcgat acagtgattg tatataaggc aggggacatt attcctgctg
    13801 tcttaaatgt cgttatgagt aagcggaacc agcaagaagt catgcttatt cctaaactat
    13861 gcccatcttg tggtagtgaa ttagttcatt ttgaagatga ggttgctttg cgttgtatta
    13921 atccgttgtg tcctagtttg attcagcgaa gtttggagca ttttgcaagt cgtgatgcca
    13981 tgaacattac tgggctggga ccagctattg tggaaaaact atttttagcg gggtttgttc
    14041 atgatgttgc tgatatttac cagttgacca aagaagattt catgcaatta gatggcatca
    14101 aagaaaagtc agctgataaa ttgctcgctg cgattgaggc ttctaaatca aattcagctg
    14161 aaaaactgtt atttggtcta ggaattcgtc atattggctc taaggttagt cgcttaattt
    14221 tagaggtata cggagatatt tctgctcttt taaccgctaa agaagaggaa atcgcaagga
    14281 tagatggtct tggctcaacg attgctcaat cacttactca atactttgaa caaaaaacgg
    14341 ctgcgatttt agtagacgag ttaaagacag caggtgtcaa catgcattac tcaggtcaaa
    14401 aagttaatag tgacgcagcg ctttttggtc taactgttgt tttaactggc aaattaaatc
    14461 agctgaaccg aaatgaggcc aaagataaat tagaggcatt aggtgccaaa gttactggaa
    14521 gtgtatctaa gaaaacagat ttagttattg caggtagtga cgctggttct aagctagaaa
    14581 aagcaaagag cttaggaatt cggattgaag atgaagattg gctacgccag ctttaagtga
    14641 ggtaatgtta tgaaaaaaca attgagagca cgtctcattt ataatccaac gtcaggacaa
    14701 gaacttatga gaaaaagtgt tcctgaagtt ttagacatat tagaagggtt cgggtatgaa
    14761 acatctgcct ttcaaacaac agcccaaaag aactctgctc taaatgaagc aagaagagcg
    14821 gcaaaggcag gttttgactt attgattgct gctggaggtg atggcactat taacgaagtg
    14881 gtcaatggaa ttgctccctt gaaaaagcgc cctaaaatgg ccattattcc aacaggtacc
    14941 actaatgatt ttgctagagc attaaaagta ccaagaggaa atccgagcca agcagcaaaa
    15001 cttatcggaa aaaatcagac tatccagatg gatattggta gagctaagaa agatacttat
    15061 ttcatcaata ttgctgcagc aggaagtttg acggaattaa cttacagtgt accaagtcag
    15121 ttaaaaacga tgtttggata cttggcttat cttgctaaag gagtagaact gctcccaaga
    15181 gttagcaatg tgcctgttaa aattacgcat gacaaaggcg tctttgaagg tcaagtttct
    15241 atgatttttg cagctattac caattctgtt gggggatttg aaatgattgc tcctgatgca
    15301 aaactagatg acggtatgtt tacgctcatt ttaataaaga cagcaaatct ttttgaaatt
    15361 gtacatcttt tgcgtttgat tttggatggt ggtaagcata ttacagatcg ccgtgtcgaa
    15421 tacattaaga ccagtaaaat agtcattgaa ccccaatgtg gtaagcgaat gatgattaat
    15481 ttagatggcg agtacggagg agatgctcca attacattag agaacctaaa aaatcatatc
    15541 actttttttg cagatactga tttgatttct gatgacgctt tagtcttaga tcaggacgaa
    15601 ttggaaattg aggaaatcgt aaagaaattt gctcatgaag tagaagactt aggacaagaa
    15661 ttagaagaat aatacaatag ttattagcta ctgacagttt agtcaaatgc actactatct
    15721 agaatctaag atttttaaat caattgaggt agtgtttttt gatgcgctca aagagtcaat
    15781 ttattcatat gaggggccta tttgaggtct ctcttttttg atcatatgca agaaaatgcc
    15841 atgttttagg ggtgttatta tacccttttt ggaatcttgt tgcctttttg ttataataag
    15901 agtgtaattc tatttttaaa aagatcttaa caaagacaga ctcgtttatc aaaaaggtta
    15961 gtattagtct aagaaagcgt acccagacta aagaaatctg ttgacattct taattttaag
    16021 gaatagaata gcaaagtaaa aaaaatttta aggagtattc tactatgaat cctattttcg
    16081 cattggcttt ggcctgtttt ggtgtttctc ttgctgaagg tttcttgatg gcaaatcttt
    16141 tcaaagcagc ttctcgccaa ccagaaatca ttggtcaatt acgttcatta atgatcttgg
    16201 gtgttgcctt tatcgaaggt actttcttcg ttacccttgt tatggccttc attcttaaat
    16261 aacagcctat tttataatag aaaaggaggg tgttagatgg aagaagctaa aatacctatg
    16321 ctgaagcttg gtccaataac ctttaatttg accctacttg ctgtttgtat tgtcacaatt
    16381 gcgattgtct ttgcctttgt tttttgggca agtcgccaaa tgaaattgaa accagaaggg
    16441 aagcaaactg ctttagaata tttaatcagt tttgtggatg gtattggaga agagcactta
    16501 gatcataatc tacaaaaatc ttattcgctg ttactcttta ccatttttct ctttgtagct
    16561 gtcgctaata atttagggtt atttactaag ttagagacag ttaatggcta taacctatgg
    16621 acctcgccaa cagccaatct ggcttttgac cttgctctat ctctttttat taccttaatg
    16681 gtacacattg aaggggttag acggcgtggc ttggttgccc atttgaaacg tttggctaca
    16741 ccgtggccaa tgactccgat gaatttatta gaagagttca caaatttctt atcacttgcc
    16801 attaggttat tcggtaatat ctttgccggg gaagttgtta caggtttgat tgttcaactg
    16861 gccaattatc gagtttattg gtggccgatt gctttcctag tcaatatggc gtggacagcc
    16921 ttttcagtct ttatttcctg catacaggct ttcgttttca caaaactgac agcgacctat
    16981 ctaggaaaga aagtcaatga atcagaagaa taaggaagga gaacaaacga atgtcaatca
    17041 catttggtga actcgttggg aattttattc tagtaacagg ttctgtaatc gtcttgttac
    17101 tcttgatcaa aaaattcgct tggggtgcga ttgaatcgat tttacagaca cgctcacaac
    17161 aaatctctcg agatattgat caggctgagc aatcacgtct aagtgctcaa cagttagagg
    17221 caaaaagtca agctaaccta gatgctagtc gtttacaagc aagtaaaatc attagtgatg
    17281 ccaaagaaat tggtcaatta caaggtgata aattggtggc agaagctact gatgaagcaa
    17341 aacgcttgaa agaaaaagcg ttgacagata ttgaacaaag caaatcagac gctatttcag
    17401 cagtcaaaac agaaatgtct gatttaacgg ttcttttagc ggaaaaaatt atgggagcca
    17461 atcttgataa gacggcgcaa agccagctta ttgacagtta tcttgatgac ttaggagaag
    17521 cttaatgacc aaaaaagaac aggctcttat cgagcaatat gcaaaaagcc ttgttgaggt
    17581 ggcgagtgaa catcattctc ttgatgtctt acaagctgat gtgcttgcga ttttagagac
    17641 gtttgtaaca actaatcttg atcaaagtct atcaagtcaa gctgttccgc atgctgaaaa
    17701 aataaaattg ctaaccttat taaagggaaa taattctgtt tatatgaata atttcttgaa
    17761 tctcatttta caaaacgaac gtgaagctta tttgtatcaa atgcttcagg ctgttttaaa
    17821 tgaaattgca atagtttcaa atcagtatga tgtgactgtt acctcatcac tacctttgac
    17881 tgaggagcaa aaaagccgtg ttcgagcagt tgttgcaaag aaatttgctg taacagcggg
    17941 tcgtttaatt gaaaaagtag atccttcgct tattggagga tttattatca gcgtcaataa
    18001 taaagtaatt gataccagta ttcgtcgtca attgcaagca tttaaaatga atttaaaata
    18061 gaaagtggtg tgacttttgg caattaatgc acaagaaatt agcgctttaa ttaaaaagca
    18121 aattgagaac ttccagccaa atttcgatgt cacagaaact gggatcgtta cctatattgg
    18181 tgacggtatt gcacgtgccc gtggattaga taatgccatg agtggtgaac ttcttgaatt
    18241 tgaaaatggt gcctacggga tggctcaaaa ccttgagtca aatgatgtgg gtattattat
    18301 tcttggtgat ttttcagcaa tccgtgaagg agatgtggtt aagcgcaccg gtaaaatcat
    18361 ggaagtacca gttggtgaag ctctcattgg acgtgtggta aacccacttg gacaaccagt
    18421 tgatggcttg ggagatattg aaacaactgg ctttagacca gtagaaacgc cagctcctgg
    18481 tgttatgcag cgtaaatccg tttctgaacc cttacaaact ggattaaaag caattgatgc
    18541 tttggttcca attggtcgtg ggcaacgtga gttgattatc ggagaccgtc aaacaggaaa
    18601 aacatccgta gctattgatg cgattttgaa ccaaaaaggt caagacatga tttgtatcta
    18661 tgtggctatt ggtcaaaaag aatcaaccgt tcgtacacaa gttgaaaccc ttcgccgtta
    18721 cggtgccttg gattatacta ttgttgtgac agcgtcagcc tcacaaccat caccattgct
    18781 ctttatcgct ccttatgcgg gtgttgccat ggctgaagaa tttatgtacc aaggcaagca
    18841 tgtcttgatt gtctatgatg atttatcaaa acaagcggtg gcttatcgtg aattgtctct
    18901 cttgcttcgt cgtccaccag gtcgtgaggc ttacccaggg gatgttttct acttgcatag
    18961 ccgtcttttg gaacgctctg caaaagtttc tgatgactta ggtggaggtt ctatcacagc
    19021 tctaccattt atcgaaacac aggccggaga tatctctgca tatattgcga ctaacgttat
    19081 ttcgattaca gacggacaaa tcttcttgca agagaacctc tttaattcag gaattcgtcc
    19141 agcgattgat gcaggatcat ctgtctcacg tgtaggtggt tccgctcaaa ttaaagcgat
    19201 gaaaaaggtt gctggtactc ttcgtttgga tttggcttcc tatcgtgaat tagaagcctt
    19261 tacccaattt ggttcggacc ttgatgctgc aacacaagca aaacttaatc gtggtcgccg
    19321 tacggttgaa atcttgaagc aaccattgca taaaccgtta cctgttgaaa agcaagtcgt
    19381 tattctttat gcccttactc atggtttctt agatgatgtt cctgtagatg atattttggc
    19441 ttttgaagaa gctctttacg actactttga cgttcattac aatgatttat ttgaaactat
    19501 ccgtaccaca aaagaccttc ctgaagaagc tgcccttgat gccgctatta aagcgtttaa
    19561 agaacactca aactttaagt catagaggga ggatactagt atggcaggct ctctaagtga
    19621 aattaaagct aaaattattt caactgagaa aacaagtaaa atcactagtg ccatgcgtat
    19681 ggtttcttct gcaaaacttg ttaaatctga gcaagcagct cgtgattttc aaatttacgc
    19741 ctcaaaaatt cgccagatta ctacagattt attgaaatca gaattaacca taggatctga
    19801 taatccgatg ttggtgtctc gtcctgtcaa aaaaacaggc tatattgtca tcacgtctga
    19861 taaaggactt gttggaggtt acaattcaaa aatcttgaaa tctgttatgg atatgattac
    19921 agagtaccat gctgatggtg actatgaaat catttctatt ggtagtgttg gttcagactt
    19981 cttcaaagca agagggatga atgtggcttt tgaacttcgt ggacttgcgg atcaaccaag
    20041 ttttgaacaa gtgagacaaa tcatttcaca atccgttgac atgtttgtca atgagatttt
    20101 tgatgagtta tatgtctgtt acaatcacca tgtgaatagc ttaaccagcc aagtccgtgt
    20161 tcaacagatg ttaccaattt ctgacttggt tgctgatgaa gcagcagaag aaggtgttac
    20221 tgggtttgaa ttggaaccta atcgtcatga tattttagat caattgttac ctcaattcac
    20281 agaaagttta atttatgggg ctatcattga tgctaaaacg gctgaacatg cagcaggtat
    20341 gactgccatg cagacagcaa ctgataacgc taagaatgtc attaacgatt tgaccatcca
    20401 atataaccga gctcgtcaag cagcaattac acaagaaatt actgaaattg ttgcaggagc
    20461 aaatgcacta gaataaaaaa taacgctgac tagcgattag gttattgtca gcattcaatt
    20521 ttatcaatcg agataaaatg acttatggga cttttctatt gaaagactgc tcttttcagt
    20581 ataaaagaag ttagcaagac taactaagcc ctgactatcg aatataagga gaaatgaatg
    20641 agctcaggca aaattgctca ggttgttggt ccagtagtag acgttatgtt tgctagcggg
    20701 gacaaacttc cagagattaa taatgcattg attgtttata aagatagtga taaaaagcaa
    20761 aaaatcgtcc ttgaagttgc tctggaactt ggtgacggta tggtgcgaac aatcgctatg
    20821 gaatcaactg atgggcttac acgtgggtta gaagttcttg acactggtcg tgcgattagc
    20881 gtaccagtag gtaaagaaac tttgggacgc gtctttaatg tacttggaga aaccattgac
    20941 ttggaagaac catttgcaga agacgttgac cgtcagccga tccataaaaa agcaccatcg
    21001 tttgatgaat tatcaacatc atcagaaatt cttgaaactg gtatcaaggt aattgacctt
    21061 cttgcccctt accttaaagg tggtaaagtt ggacttttcg gtggtgccgg agttggtaag
    21121 actgtcctta tccaagaatt aatccacaat atcgcccaag aacacggagg tatttcagta
    21181 tttaccggtg ttggtgagcg aacacgtgaa ggaaatgacc tttactggga aatgaaagaa
    21241 tcaggcgtta ttgagaaaac tgccatggtt tttggtcaaa tgaatgagcc gcctggggca
    21301 cgtatgcgtg tagcccttac tggtttaacc attgctgagt atttccgtga tgtagaaggc
    21361 caagatgttt tgctctttat tgataatatc ttccgtttca ctcaggcagg ttcagaagta
    21421 tcagccctct taggccgtat gccttctgct gttggttacc aaccgaccct tgctactgaa
    21481 atgggacaat tgcaagaacg tattacgtca actcaaaaag gatctgttac ttctatccaa
    21541 gcgatttatg tgccagccga tgactatact gacccagcgc cagcaactgc atttgctcac
    21601 ttggattcaa caactaacct tgagcgtaaa ttgactcaaa tgggtattta ccctgcggtt
    21661 gacccattgg cttcaagttc acgggcctta tcacctgaaa ttgttggtga agagcactat
    21721 gctgtggcaa cagaggttca acgtgtactt cagcgctacc gtgaattaca agacatcatc
    21781 gctattttgg ggatggatga attatcagat gaagaaaaaa cattggttgg acgtgcgcgt
    21841 cgtatccagt tcttcttatc acaaaacttt aatgttgctg aacaatttac aggtcttcct
    21901 ggttcttacg tgccagttgc tgatacagtt cgcggcttta aagaaattct tgaaggaaaa
    21961 tacgatgaac ttccagaaga tgccttccgt tcagttggtc caatcgagga tgtgattaaa
    22021 aaagccgaaa aaatgggctt ttaatgaggt gatgccatga cacaaatgac tgttcaagtg
    22081 gtaacgccag atggaatcaa atatgatcac catgctaaat ttatttcggt aacaacacca
    22141 gatggggaaa tggggatttt acctaatcac atcaatttga ttgcaccttt gcaagttcat
    22201 gaaatgaaaa ttcgccgagg tggtgaagat gaaaaagtgg actggattgc aatcaatggt
    22261 ggtattattg aaatcaagga taatgtggtt accattgtcg ctgattctgc agaacgtgac
    22321 cgtgatatcg atgtcagccg agcagagcga gcaaaactaa gagcagaacg tgaaattgca
    22381 caggctgaaa caacccataa tattgatgag gttcgtcgtg ccaaggttgc cttgcgccgc
    22441 gctttgaatc gtatcaacgt tagtaaaaaa taagtggtgt tgataaaaga caaggataag
    22501 taagaaaggt ttttaaccta ttattttgtt tactgattct ttttaacatc agtttctgag
    22561 agtttgacca tactaccttc tctaaacacg ttattattgt tgagaggagt tatatggggg
    22621 aactcttttt tgtatccacg ttgttagtag aaactcagta atgacgctta atatattttt
    22681 aggctatcaa cttagtcaga gaagatgtca acttaattga taagttggac ggatcaagat
    22741 ggtatgttat aataatccta tggaattatt aatgaagatc attgcctttt cgtgtcattt
    22801 attttttatt ggccttagtt accaattatt gattagtgtg attgactgga caaaatttag
    22861 tcattatcat ccagaaaatc ttggccggct acgacttttt gtctttttat tagctactgc
    22921 cctagggtat ttggtgagcc attgtatgct ggaattgctt caaattagcc agacgctctt
    22981 ttttgagttc cgctaatact ggaataaaag aagtatggta taattttact acgactaaga
    23041 gatagataag ggagaaaatt gtggataaaa taatcattga aggtggtcaa acacgcttag
    23101 aaggagaagt tgttattgag ggtgctaaaa acgcagttct tcctttactg gcagcatcta
    23161 ttttaccttc aaaaggaaaa acaattctta gaaacgttcc tattctatct gatgttttta
    23221 ccatgaataa cgtggtacgt ggtttagata ttcgtgttga ttttaatgaa gcagctaacg
    23281 aaatcacagt tgatgcctca ggacacattt tagatgaagc cccttacgag tacgtgagcc
    23341 aaatgcgtgc ctctattgtt gttttaggac caattttggc acgtaatggc cacgcaaaag
    23401 tatcaatgcc tggaggctgt acgattggca gtaggcctat taatttgcac ttaaaaggat
    23461 tagaggctat gggggcaacg attactcaaa aaggtggaga tattaccgct caagcagatc
    23521 gactgcaagg tgccatgatt tatatggact tcccatctgt aggagctacc caaaacttga
    23581 tgatggctgc cactttagct gatggtgtga ccactattga aaatgctgct cgtgagcctg
    23641 aaattgttga tttagctcaa tttttgaata aaatgggagc tagaattcgt ggtgctggaa
    23701 cagagacgtt aacgataaca ggtgtcacgc atttacgagg cgtagaacat gatgttgttc
    23761 aagatcgtat agaagccggt acatttatgg ttgcagcggc gatgacttca ggcaatgttt
    23821 tgattagaga tgctgtttgg gaacataatc gtccattgat ttcaaaatta atggaaatgg
    23881 gtgtttctgt aacagaagaa gaatacggta ttcgcgttca agcaaacacg ccaaagctca
    23941 aacctgtaac ggttaaaacc ttgcctcatc caggttttcc aacagacatg caagctcaat
    24001 ttacagcttt aatggcagtg gtcaatggag agtctactat ggttgaaact gtctttgaaa
    24061 atcgatttca acatctggaa gaaatgcgac gcatgggctt acaatctgaa atccttaggg
    24121 aaactgccat gattcatggt ggaagacaac tgcaaggtgc tcctgtgatg tcaacagatt
    24181 tacgtgccag tgctgccctt atcttgacag ggattgttgc tcaaggagtt acaatagtta
    24241 ataatttggt tcatttagat cgtggctact atcaatttca tgaaaaatta gcaaagcttg
    24301 gagctactat tagtcgtagc agtgaggtct agcttatgac aaatggttta aaatatgtct
    24361 tagaacaaat gttattactt ttcataattg ctgccttggc gtgtcttttt ttagccattg
    24421 gacttatgat tggttatagt tttatgggag atggccagag tccatggcat attttatcta
    24481 tggataagtg ggcagagtta gtgaataaat ttactggaaa gtaggccttg cctacttttt
    24541 atagcatctg agaggaagta tgttaacaag gaaaaaacga aaaagggtgc aagagcaaaa
    24601 ggttcctaaa agagctaatg ccttacttac taagtcgaca cgacagtatc gaaatcgcta
    24661 tcaaacggat aatgcttatc gtaactttaa gccagcaggt tggcaccgat tgcaccactt
    24721 aaaaggaagt tatgatcacg cggttgatag agggcatttg ctaggttatg ctttagttgg
    24781 tggactgaaa ggttttgatg cttctactgg taatcctgat aatattgcca ctcaactaag
    24841 ttgggctaat caagcaaata aaccctactt gacaggtcag aattactatg aaggtttagt
    24901 acgtcgtgct ttagataagg ggcatcgcgt ccgctaccgt gtcaccctac tttatgatgg
    24961 tgataatcta ctagccagcg gtagccattt ggaggctaaa tcctctgatg acagcttgac
    25021 ttttaacgtg tttgttccaa atgtccaagc aggattgacc gttgactatc ggacgggaca
    25081 aatagctatc aatctctaag cgaaaagtca ctgatttaag attgtcacta agcacttttt
    25141 ttgatagaat agaactaatt gaataagtgt ctatgagact agtactaata gagaaattaa
    25201 cagggagtga gggccgtgac tggaagcctt cttaagggaa ctattaggaa ttcactcagc
    25261 taaagacaat taattaaggt ctgataacgt cagataaaaa cggatggtac cgcgtgtcaa
    25321 cgctccgctt atcaagtgga ggagtggcat gcttttttca tcgccaaaag aagggaaaac
    25381 tatggattta caagcacaat tagaggaatt aaagacaaaa acattggaga ccttacagtc
    25441 tttgacgggt aatcatacca aagaactgca agatttgcgc gtggctgttc ttgggaaaaa
    25501 gggatctttg acagaattac taaaggggct aaaagacttg tctaatgact tgcgtcctgt
    25561 ggttggtaaa caggtgaacg aagttcgtga cttattgaca aaagcctttg aagaacaggc
    25621 taaaattgta gaagctgcta aaattcaggc ccaacttgat gctgaaagca ttgatgtgac
    25681 tttaccgggt cgtcaaatga ctctggggca tcgtcatgtg ttaacacaaa ccagtgaaga
    25741 aatcgaagat attttcttag gaatgggttt tcagattgtt gatggctttg aggtggaaaa
    25801 agattattac aactttgagc gcatgaattt gccaaaggat caccctgccc gtgacatgca
    25861 agatacgttt tatatcacag aagaaatctt gttacgaact cacaccagtc ctgtgcaggc
    25921 ccgtactctt gatcaacatg atttttcaaa agggccttta aaaatggttt ctccaggtcg
    25981 tgttttccgt cgtgatactg atgacgctac ccactcacat caattccatc aaattgaagg
    26041 tttggttgtg ggcaaaaata tttccatggg agacctcaaa gggacccttg aaatgatcat
    26101 caagaagatg ttcggtgacg aacgtagcat tcgtttgcgc ccgtcatatt tcccgttcac
    26161 agaaccatct gttgaagtgg atgtttcttg ctttaaatgt ggtgggaaag gctgtaatgt
    26221 ctgcaagaaa acaggatgga ttgaaattct tggtgctggt atggttcacc caagtgtctt
    26281 ggaaatgtca ggtgttgatg caaaagagta ttcaggcttt gcctttggtt taggtcaaga
    26341 gcggattgcc atgttgcgtt atggcattaa tgacattcgt ggtttctatc aaggcgacca
    26401 acgtttctct gaacaattta actaaaacga gtcgtttgaa gacctctgtc agctatttta
    26461 tctaagattg agtgaaagtt gataggtaat gataataggt taattgtcta aggggaaagt
    26521 ccctctcgct tcaacgtcat aagggttttg acttggaact taaaatacga aaggaaatga
    26581 ctcaaatcac ggcttgagag ctttctctag ccgagtgatt tgggcactaa aattatgtta
    26641 gtatcttata aatggttaaa agaattagta gatatcgatg tgacaccagc agcacttgct
    26701 gagaaaatgt cgacaacggg tatcgaggta gaaggaattg aagtccctgc agatggttta
    26761 tcaaaactgg ttgtggggca tgtgctttct tgtgaagatg tgccagagac acatttgcat
    26821 ttgtgtcagg tagatacagg tgatgaaacg ccacgtcaaa ttgtgtgtgg cgcaccaaat
    26881 gtgaaagcag ggattaaggt tatcgtggct gtgccaggtg ctcgtattgc ggataactat
    26941 aaaatcaaaa aaggcaaaat ccgcggcatg gaatctcttg gcatgatttg ttccttgcaa
    27001 gaacttggtt tgtcagatag tattattcca aaagaatttt cagatggtat tcaaatcttg
    27061 ccagaggagg ctgtgccagg tgatgctatt tttaaatacc tggacttgga cgatcatatc
    27121 attgaattgt ccattacacc taaccgtgct gatgcgcttt ctatgcgagg tgtggcacat
    27181 gaagtcgcag ctatttatgg caagtcagta tcattccccc aaaaaaatct acaagaatct
    27241 gataaggcaa cttcagaagc cattgaagtg gccattgcct ctgataacgt tctaacttac
    27301 gctagccgtg tcgttgaaaa tgtcaaagtt aagccaagtc cacaatggtt gcaaaacctt
    27361 ttaatgaatg ctggtattcg tcctattaat aatgtggttg atgtgaccaa ctatgtgctc
    27421 ttgtattttg gtcaacctat gcatgctttt gattatgata aatttgaaga ccataagatt
    27481 gtggcgcgtg cggctcgtca aggagaaagt ttggtcacac ttgatggtga aaaacgggat
    27541 ttgaccactg aggatcttgt tattaccgtg gctgacaaac cagttgcttt agcaggtgtt
    27601 atgggtggtc aagccactga aattgatgcc aactctcaga cggttgttct tgaagctgct
    27661 gtttttgatg gcaaatcgat tcgtaaaacc agtggtcgtt taaaccttcg ttcggaatcc
    27721 tcttcacgtt ttgaaaaagg ggttaactat gcaactgttt tagaagcact tgactttgca
    27781 gcggctatgt tacaagaatt agcagaaggt caagtcttat caggccatgt tcaagctgga
    27841 caattgccaa cagaacctgt tgaagtctca actagccttg actatgtgaa tgttcgttta
    27901 ggaacagaat taacttttgc tgatattcaa aggatttttg accaacttgg atttggtcta
    27961 acaggagatg aaacaagctt cacggtagct gttcctcggc gtcgttggga tgttagcatc
    28021 ccagctgact tggtggaaga aattgcgcgt atctatggtt atgataagtt gccaacaacc
    28081 ttaccagagg cagggggaac ggctgcagaa ttaacgccaa cacaggctct tcgtcgtaaa
    28141 gtccgtggct tagcggaagg attgggcttg actgaaatca tttcgtatgc tttgacaaca
    28201 ccagagaaag ctgttgagtt tgcagtggca ccaagtcacc tgacagaact catgtggccg
    28261 atgtctgtgg agcgttcagc actacgtcaa aatatggttt cagggatgtt agatacggtt
    28321 gcctataatg tggctcgtaa acaaagtaac ttggctcttt atgaaattgg aaaaatcttt
    28381 gaacaagaag ctaatccaaa agaagacctt cctaatgaag tgaaccattt tgcttttgct
    28441 atttgtggct tagtggcaca aaaagatttc caaacccaag ctcaggcagt ggatttttac
    28501 catgctaaag gtaacttgga tactttattt gcaaacctta acctcaaggt tcaatatgtg
    28561 ccaaccaaag acctagcaaa catgcaccca ggacggacag cgcttatcct attagatgag
    28621 caagtgattg gatttgttgg tcaagttcat ccaggaacag caaaggctta tagtattcca
    28681 gaaacctatg tggcagaatt ggatatggct gctttagaag cagcgttgcc aagtgatcaa
    28741 acttttgcgg aaatcacaaa attccctgct atgacacgtg atgttgcctt gttacttgac
    28801 cgtgaggtga gtcatcaggc cattgtaaca gctattgaat cagcaggtgt aaaacgcttg
    28861 actagcatta aactctttga cgtctatgaa ggagcaacca ttcaggctgg caaaaaatca
    28921 atggcttata gccttacttt ccaaaatcca aatgacaatt taacggatga agaagttgcc
    28981 aaatacatgg agaaaatcac caaagcattg acagaacaag tcggtgctga agtacgctaa
    29041 gaaaaaaact gggcctctaa ggctccgttt ttttctgtta taatagagga aaaaagaact
    29101 ccagttcaaa tgattggaga aaaacatcag aaggtggagg aaaatcagaa tgtatcaaac
    29161 aaaaataaca ggcaaccgcc tttaccacac ggtttcgaaa ggctacggag atagtgtgac
    29221 cttatttgga aaaactgatc aaggggaaac ccctatgagt ttactggtta tcgccttgtc
    29281 ttcttgtgtg actatgtgtg tgcagggttt ttaccatcgt caatttcagc aagacacact
    29341 tgctgtttct gttgaggcta gttatgagga agaagttttt gaactacttg ttaggattga
    29401 tgatgtttta gatgacaaaa agaaagctga tttattggct tacattggaa cttattgtcg
    29461 tgtgaaacaa ctcctcaaac ctgaagttac ggtgaccatt acgttggaag gactgtctca
    29521 tgtctgatgc tagtttgaaa acttaccaaa aacaatgggc ttatcaaaag tattgggtca
    29581 tggcacactc acagcagcat tacaatgctt taagagaatt gtttaaagga aatcagtggt
    29641 cagaagaaaa ggtgttgact tttcattgtt tgattgaaga agcgcaagcc attcctccca
    29701 cagtaaaaag cttacgaacg gcatatcagc atgtttgggg gtattttaaa aaggtagcga
    29761 gtcaggaaga aaaagaccat ttcaaagatt tggatgctca gttggaaact aaatctgagg
    29821 agatgctatg ctttttacaa gagatgactg ctcattatca gccctcttat ctgctatctt
    29881 gccgtttgat taccaaaggt ccttaaatgc taaacagaaa agtagggatt tctgggaagt
    29941 tatgctaagc tagtgatata aataaggggg aatgagagat gtttttagcg cttaatgaaa
    30001 tgaaacaatc caaattgcgg tatggtttga ttgctggttt gctatgtttg gttgcctatt
    30061 tgatgttctt tttgtcagga ttggcctttg gtttgatgca ggagaaccgc tcggcggttg
    30121 atctttggaa agctgacagt gttttactag ccaaggatgc tgacgctacc ttgaccttat
    30181 cacaggtgtc cagagctcaa gaaaatcaaa taacagcaga caaggtagct cctcttgctc
    30241 aactcaatac cgtggcgtgg tcagttaaaa atcctaagga tgccgacaaa gttaaggtta
    30301 gccttttcgg gattgattct aatagcttta ttcgtcctaa cattgtaaaa ggtcgattat
    30361 ttaagactaa caaagaggtt gttttggatc aaagccttgc aaaagaggaa gcttttgcga
    30421 ttggcaagga cttttacaca tcgagttcta gtcaagcatt aactatcgtt ggttatactc
    30481 aaaatgctag atttagtgtt gcaccagtgg tttatatgaa tttggaagct tttgaaacat
    30541 taaaatatgg agaaccacta ccaaaagata agcaagttgt taatgctttt atcactaaag
    30601 gaagtttaac agattatcct aaaaaagact tccaaaaatt agatattaaa acctttatta
    30661 ctaaattacc tggttatagc gctcaacttt taacttttgg ctttatgatt agttttcttg
    30721 tcattatttc agctattatt attggtattt ttatgtatat tttgactatt caaaaggcac
    30781 ctatttttgg gattatgaaa gcgcaaggaa tttctaacaa aacgattacg accgctgtgc
    30841 ttatgcagac attctttttg agttttttag gtagtggttt agggttgcta ggtacttggc
    30901 tgacatcatt attattacca acagtagtac cttttcaaag caattggttt ttgtatttgg
    30961 ctatattcgt tagtatgatc tgttttgctc tattaggcac cttattttct gtttttaaca
    31021 ttatacgaat tgatcctttg aaagcaattg gataggaggt agtgatgtcg gttttaacat
    31081 ttaaacaagt gaccaaaaca tttcaagatg gtcatcacga aatcaacgca ttaaaggcaa
    31141 ctgacttttc cattgaagct ggagaatttg tggctattat tggaccatca ggttctggaa
    31201 aatcaacctt tttgaccatt gctggtggct tacagacccc aagttctggt cagctaatca
    31261 ttgatggcac tgattatacg catttatcag aaaaagagcg ctcacgcttg cgcttcaaat
    31321 ccgttggttt tatcttacaa gcttccaatc tgataccttt tttaacggtc cagcagcagt
    31381 tggaattggt cgatcatttg acaggaagca aagaaaaagc caaagccaat cagttatttg
    31441 acgatttagg cattacaggg ctaaaacatc agttacctca agaattatcc ggcggagaaa
    31501 ggcaaagagc ggctattgcc cgtgctcttt accatgatcc agcactgata ttggcagacg
    31561 aacctactgc aagtttggat actgaaaaag cctatgaagt ggtcaaactg ttggctaagg
    31621 aaagtaaaga aaaaaacaag gccattatta tggtcactca tgatgatcgg atgctaaaat
    31681 attgtgacaa agtctatcgg atgcaagatg gagagttatg tcaagagaga tagtagactg
    31741 gtaagagttt atgatattag aaaaaaacca aacaagcaca gcacttgttt ggtttttttc
    31801 taagtgtgac tattatcaat acgtcaccat ttccctaaag cttactatac gggatgctaa
    31861 aggtatcacc atgctcaaag tcgccatatt ggtaacctcg gtcaaaccaa cgttggcgtt
    31921 gcttagaagt gccatgtgta aaactatcag gaacggttct gccataggtt tcttcttgca
    31981 gagtatcatc cccaactgcg tgagctgctg ccattgcttc ctcaatatct cctttttcca
    32041 aaaggccttg cccttgaaca taattagccc aggcaccagc atagtaatca gattgtaatt
    32101 ccaacttgac gttgagctga ttggctttag cctttgattt tccttgtcta gcgctagcgt
    32161 aattatccat aattcccaat tcattttgga tgtggtggcc aacttcatga gcaatcacat
    32221 aggccatagc aaaatcacct tttgcgccgt acttggttga tagttcatta taaaaagaaa
    32281 tatctaaata cactttttga tcgcctgggc aataaaaagg accagaagag gcttgccccc
    32341 tgccacaagc ggtttgagtt gctccagtat atagaactaa tgttggttta tgataagtta
    32401 accctttctc acgaaatgtc ttagtccaat agtcctcggt agaggcgaag accttactga
    32461 caaaagaaac ctgttcttga ctagccttgt caccatttgt acgcgttact tggcttgatt
    32521 gataggcatt gttgttggta gaagaaggct tgcctcctaa aacaccagat aggccaccac
    32581 ctcccataac taggagaagg agaagaataa ccagcttggt tttccaacct cctcgtgaaa
    32641 agagtaattg aagcaggaga ccgcccccta ggccgccgcc cccaaaagaa ccagacgatt
    32701 gaccacgtct atcttcaacc tgttgacttt ctctcaaatc atccgttttc ataagtttct
    32761 cccatctatt tcttgatttt attataaaat aattctatta gaattgctat ttttatgatg
    32821 agattataac taaaaatagg aaaagcaata ggtatttgct ataatataac aagggtagat
    32881 tcagtttgta taaaggagtc atatgaaatt aatttacaca gagatgagtt actcgatgac
    32941 agagattttg gtgaatgaag cacgaaaagc tgctgaccaa ggttatcgag tgttctatat
    33001 tgctccaaat tctctttcat ttgaaaagga aagggaagtc ttaaccttat tgcctgaacg
    33061 agggactttt tcgataatag tcacccggtt cgttcaaatg tcaaggtatt ttacagttga
    33121 gagctctcct tctaagcaac atctagatga cacgactttg gctatgattt tttatcgggc
    33181 cttgatgcaa ttaaaaccag aagatttgcc gagttatggt cgtttgcaaa ataattcggt
    33241 ttttattgaa caactagttg agttatataa agaattaaaa aacgcacaat taagcgtaca
    33301 tgatttaaca gggttagacc atcctcaaaa acaagaagat cttattaaaa ttattgagct
    33361 tgcagagacg atcatgattc agcaagatta taatcaagat agtcctctac aatcttttgc
    33421 aagagcaatt aagttaggac ttttaaataa ccaactatca aaaacagttg ttgttattga
    33481 tggtttttca cgtttttcag ctgaagagga ttatttatta tcacttttaa ataacaactg
    33541 tcaagaggtc atcattggca gttatgtgag tcaaaaagct tatcaaaaat cttttattaa
    33601 gggaaatatc tatgaggcta gccttcattt tttgcaagat ttggctcaaa aataccatat
    33661 caagccggta tttgcgacct ctaatcaagt gtttaaacca gccttttcac ggctaacaca
    33721 attatttgaa gcaactcatg atttttcaca agtagactgg caactccaaa agagtgatct
    33781 tgatcacttt agcctttggc aatgtcatca tcaaaaagag gaaattgaac atgtagcaaa
    33841 atccattcgg caaaagctat atgaaggtta ccgttataag gatatcttag tgttgctagg
    33901 agatatggat gcttatcaat tacaaattgg gcctatcttt gataagtttg aaatccccta
    33961 ctatttagga aaagcagagc ctatggctgc ccatccatta gtccaattta tagaatcgct
    34021 cgaacgaagt cagcgctata attggcgtcg tgaagacatt ttaaacatgt taaaatcagg
    34081 actttttggt tgttttgatg atagtgatat tgatcgcttt gaggaatata ctcagtttgc
    34141 agatattaaa ggatttacta aattttcaaa gccttttacc attaactctt ctaggcagta
    34201 tcctcttgac tttttaaatg aaatgagaca agacatcgtt ttacctttgc aagaattgtt
    34261 taagagtcaa aaacaacttg gtgcttcact tgttgacaaa ttaatacttt ttttaaaaaa
    34321 gattagatta gctgagaata tgcaaggttt agcacagtcc caattagagg tggaaaaaaa
    34381 cgaagaagtt tggaaaaggt ttacagatat tttgacttct tttcatcata tctttggcca
    34441 agaaaaatta cggctatcag attgccttgc tttaattaaa acgggaatga aatcagctca
    34501 gtatcgtgtt gttccagcga cattagatgt tgtcactatt aaatcttatg accttgttca
    34561 accacattca aaacctttcg tttatgcaat tggtctaact caatcacatt ttcctaagca
    34621 aattcaccat tcaggactac tttctgatca agagcgtgct agaattaatg aaataagaaa
    34681 ttatcgtcat tttgatattg ctagtgccga aaatagtaaa aaaaaccatc aaactgcgtt
    34741 atctctgttt aatgctgcta ctaaggagtt agttcttagt gtttcaacgg taatcaacga
    34801 gacattcgat gatctatctc cttatcttaa agaattaata aactttgggt tacctctttt
    34861 ggataaaggc aaaaactatc tatcttatga taatagcgat attggtaact ataaagctct
    34921 cttgtcacaa attattgcta ttaaccgaca agatcttata gaaatgtcag atcaagataa
    34981 gatgttttgg actgttgtct tacgttatct caggaaacag ttaagaaagc aacagctaga
    35041 gctacctact tcagattatc gtttatcaac aaagcctttg tctaaagaag ttatcgaggt
    35101 atgttttcca aagggaatcc ctttaaagct atctgcaact gctttaaccg ttttttataa
    35161 taatcagtac aactattttt tgaaatatgt tttgaattta aacaaaacag aatccattca
    35221 tccagattcc agaattcatg gtcaatactt gcatcgtgtc tttgagcggt taatgaaaga
    35281 tcacacgcaa gaaccgtttg ataataagtt aaaacaagca atctaccata ccaatcaaga
    35341 aagttttttt cagcaggttt accaagataa tgccgaggct gagtacagtt tagctatact
    35401 agaagatatt gttagatcaa cagcacctat cttgcaactt aaccaaaaca tacaggtcat
    35461 tgatcaagaa aagaactttc agctggatat gggaaatgag atattagtcc acgggatcat
    35521 tgatcgtatt gaccagctga gcgacggtag cttgggcatt gttgactata aatcaagcgc
    35581 gaatcaattt gatattggga ccttttataa tgggttgagt ccacaactaa tgacttacct
    35641 cgcagcctta aaacagattg caccgcacga tataaaccaa ttatttgggg ctatgtacct
    35701 tcatttgcaa gatcctaaat tggatctagt aacatttaaa caaattgata acacattagt
    35761 ggagagtatc tataaagcgt tgacctataa aggtattttt tcagaagtcg aaaaagagca
    35821 tctatctact ggtgcttacc aaaccaaaaa tgctctttat tccaatgacg aattggaaac
    35881 acttttaaat tataacaagt acctctatct taaagctgct aaacacatta aaaagggaca
    35941 ttttttgatt aatccttata caagcgatgg taagacagtt caaggagatc aattaaaagc
    36001 cattacccgt tttgaagcag atcttgacat gggacaggca aggcgactag tgactctccc
    36061 tgctaaggag aaaaaagagt gctttttaac attaatgaga aaggagagcc acttgtgatt
    36121 tcttttgccc catttttaag ccccgaagct attaaacatt tgcaagaaaa cgaaaggtgc
    36181 agagatcagt ctcaaaaacg cacagctcaa caaattgaag caatttatac tagtggccaa
    36241 aatatacttg tatcagcttc tgctggttca ggaaaaacct ttgtaatggt cgaacgcata
    36301 cttgataaaa ttttgagagg tgtttcaatt gatcggcttt ttatctcaac ctttactgtt
    36361 aaagcagcta cagaactgcg tgagcggatt gaaaacaaat tatactcaca aattgctcaa
    36421 actacagatt ttcaaatgaa agtttattta acagaacaat tgcaatctct ttgtcaagct
    36481 gatattggta ctatggatgc ttttgcacag aaagtagtaa gtcgctatgg ttatagcatt
    36541 ggcatttcat cccaatttcg tatcatgcag gataaagcag aacaagatgt tttaaagcaa
    36601 gaggtgttta gcaaactctt taatgagttt atgaatcaaa aagaggcacc ggtgtttagg
    36661 gctcttgtga aaaatttttc tggtaactgt aaagacactt cagcttttag agagttagtt
    36721 tatacttgtt attcttttag ccaatcgaca gaaaacccaa aaatatggtt gcaagaaaat
    36781 tttctaagcg ctgctaaaac ttaccaaaga cttgaagata tcccggatca tgatattgaa
    36841 ctcttacttt tggcaatgca agacactgca aatcagctaa gagatgtgac tgatatggaa
    36901 gattatgggc agctgactaa ggcaggtagc cgatctgcta aatacactaa acacttaacg
    36961 atcatagaaa agttgtctga ttgggtgcgt gattttaaat gtttgtatgg aaaagccgga
    37021 ttggatcggt tgatcagaga tgtgacaggc cttataccat ctgggaatga tgttacagtc
    37081 tcgaaggtaa aataccctgt ttttaagacc ttgcatcaaa aattaaaaca atttaggcat
    37141 ttagaaacaa ttttaatgta tcagaaagac tgtttttcct tattggaaca gttacaagat
    37201 tttgtgcttg cgttttcaga agcttattta gctgtcaaaa tacaagaaag tgcttttgaa
    37261 ttttcagata ttgcacactt tgcaatcaaa attttagagg aaaatacgga tattcgccaa
    37321 tcctatcagc aacactatca tgaggtgatg gttgatgaat atcaagataa caatcatatg
    37381 caagagcgac tcctgacctt actatcgaac ggtcataatc gctttatggt aggagatatc
    37441 aaacaatcga tctatcgatt tcggcaagcc gatcctcaga tttttaatca aaagtttaga
    37501 gactatcaaa aaaaacctga gcaggggaaa gtgattttac tcaaagaaaa ctttcgtagc
    37561 caatcagagg tgttaaatgt cagcaatgct gtttttagtc acttaatgga cgaatcagta
    37621 ggagacgtct tatacgatga gcaacatcag ttaatagcag gtagtcatgc tcaaacagtc
    37681 ccctatctag accgtcgtgc tcagttattg ctatataata gcgataaaga tgatggcaac
    37741 gccccttcag atagtgaggg tatttcattt agtgaggtta caattgttgc caaagaaatt
    37801 attaagcttc acaatgataa gggtgtccct tttgaagaca ttacgttact cgtttcttca
    37861 agaacaagaa atgatatcat ttctcataca ttcaatcaat atggtattcc tatagtaaca
    37921 gatggtgggc agcaaaacta tcttaaatct gttgaagtga tggttatgtt agatacatta
    37981 cgcaccatta ataacccaag aaatgattat gcccttgtgg ctttactgcg ctcaccgatg
    38041 tttgcctttg atgaggatga tttagcaaga atagcacttc aaaaagacaa tgagctagat
    38101 aaagattgcc tatatgacaa gatacaaagg gctgtgattg gaagaggtgc tcatcctgaa
    38161 ttgattcacg ataccttgct tggcaagtta aatgtttttt taaagacgtt gaaaagctgg
    38221 cgtcgatacg ctaagctagg gtcgttgtat gacttgattt ggaaaatttt taatgatcgt
    38281 ttttattttg attttgtagc tagtcaagca aaagcagaac aagcacaagc taatctatac
    38341 gcattagctc tacgtgctaa tcagtttgaa aaatcgggct ataaagggct ataccgtttt
    38401 attaaaatga ttgataaggt acttgagacg caaaatgact tagctgatgt ggaagtggct
    38461 actcctaaac aagctgttaa tttaatgacc attcacaagt ctaaaggttt acaatttccg
    38521 tatgtattta tccttaattg tgacaagcgc ttctcaatga cagatattca taaatcattt
    38581 attctgaatc ggcagcacgg tatcggtatc aagtaccttg cagatatcaa aggtttactt
    38641 ggtgaaacaa cactcaattc tgttaaagta agcatggaaa ccttacctta tcaattgaac
    38701 aaacaagagt tgcgcttagc aactttatca gaagaaatgc gcttactgta tgttgctatg
    38761 acacgagctg aaaaaaaagt ttattttatt ggtaaagcta gtaagagcaa aagtcaagaa
    38821 atcacagatc ctaaaaagtt aggcaaactt ttgccgctgg ctttacgaga acagttattg
    38881 acattccaag attggctatt agcaatagca gatatatttt caactgaaga tctttatttt
    38941 gatgttcgct ttattgaaga tagtgatttg acacaagagt cagtcggacg acttcaaaca
    39001 ccacagttat taaatccaga tgatcttaaa gataatcgtc aatcagaaac aattgcacgg
    39061 gctttagata tgttagaagc agtgtctcaa ttgaatgcca attatgaagc agctattcat
    39121 ttgccaacag ttcgaacgcc tagccaactt aaggcaactt acgagccttt attagaaccc
    39181 attggtgtag atattataga gaaatcttct cgatcgctat ctgattttac tttgccacat
    39241 ttttcaaaaa aagcaaaagt tgaagcaagt catattggat cagctcttca tcagttgatg
    39301 caggtgctcc ctttgtcaaa accgataaat caacaaacgc ttttagacgc tttaagagga
    39361 attgatagta acgaagaggt aaaaacagct cttgatctca aaaaaataga gtcgttcttt
    39421 tgtgatacaa gcctaggcca attttttcag acttaccaaa aacacttgta tcgagaagcg
    39481 ccatttgcta ttttaaaact tgaccctatc agtcaagaag agtatgtcct acgtggtatt
    39541 atagatgcct actttttgtt tgatgatcat attgtattag tggactataa aacagataaa
    39601 tacaagcagc ccattgagtt aaaaaagcgt taccaacaac agttggagtt atatgcagaa
    39661 gctctcactc aaacgtataa acttcctgtg actaagcgct atcttgtttt aatgggaggt
    39721 ggaaagccag aaattgtcga agtttaaggt tgttgtgaca caagggtatt ttgcaaatga
    39781 taatagtata gttgaggatt ttacgaaatg cttgaaaagc tattgacctt tgaataataa
    39841 tacaatataa taagttttat tagcgacaaa aaggaataaa tatactatga attttaaaaa
    39901 aataagattt ggttttttgc tttgcctcct actttatcct ttagcagctt gtaacaagtc
    39961 tgaacaactt aatcactacg aaagaattaa aaaaacaaga aaattagtcg ttgctgtaag
    40021 ccctgattat gctccttttg aatttaaagc tttagttaat ggaaaagata ctattgttgg
    40081 agcagatgtt caattagctc aggctattgc tgatgaatta gacgttgatc ttgagctttc
    40141 accaatgagt tttgataatg ttttgtctag tttacagact ggtaaagctg atcttgctat
    40201 ttcaggaatc tcacatacta aagaaagagc taaagtatat gatttttcaa ttccttacta
    40261 tcaggcagaa aacgctatag tgatgagagc atctgatgct aaagtgacca aaaatattag
    40321 tgacctaaac ggtaagaaag tagccgctca aaaaggtagt atcgaggaag gtttagttaa
    40381 aatacaatta ccaaaggcca atctgatttc tttgactgct atgggagaag ccattaatga
    40441 actaaaagca ggacaagtct atgcagttac cttagaagca cctgtagctg ctggtttttt
    40501 agcccaacat aaggatctgg ctttagcacc ctttagctta aaaaccagtg atggagatgc
    40561 caaagcagtg gcccttccta aaaatagtgg agacttaacc aaagccgtta ataaggttat
    40621 tgctaagtta gatgagcaag aacggtacaa gtcatttatt gcagagacaa tagcactaac
    40681 gaaaaatact atgaagtaat aaggttaata aaaactttat tagtatccgt tggaaaagtg
    40741 tttggaataa acaataaaag aggtttgact tttttaaaaa aataatgtaa tataattggg
    40801 aacgtgaaaa tgttacaata tcttgaggag gtgaaacaca tgtcaaaaac agtagtacgt
    40861 aagaatgaat ctcttgacga tgctcttcgt cgcttcaaac gttctgttac taaagctggt
    40921 actcttcaag aatcacgtaa acgtgaattc tacgaaaaac cttctgtaaa acgtaaacgt
    40981 aaatcagaag cagctcgcaa acgtaaaaaa ttctaatgga taaaaaataa aacagttctc
    41041 acaattagaa ctgtttttat tttttatcca gaagaagcaa gggagctttt ttgatatcaa
    41101 aaaaagtagt tagacatgcc taactacttt atcaaaaatc gctttatttt tgagccaaca
    41161 aatcacggat ttctgtcaat aattcttctt gagtaggagc tgcagcttct ttttcctttt
    41221 taggcatagc tttttcagcg gcttttacaa caaagaaaag actggtaccg atgataagaa
    41281 aattaataac ggctcctaaa aagctaccat atttaacacc attccatgac aattgagtga
    41341 tgttttcaac atttgcagct ttcaaagctg ggtttaaaat aagcggtgtg ataatatcgt
    41401 tcacaaaaga agtgacaata gcaccaaaag ctcccccgat gataactgct acagcaagtt
    41461 caataatgtt tcctctaaac aaaaatgctt ttaattcttt aaccattaaa cattccccct
    41521 ttttaatatc tctaagttaa gcatagcata attagtaaac aaaatccaat ggaatcactt
    41581 cagtttttaa atttacaaaa aagagtttcg gtggtataat aaaacgtaaa actaaaatgg
    41641 gatttttatg gggaggtgac gatttggcaa ttgacaaaga aatgatttcc caagtaaaaa
    41701 atagcgttaa tattgtcgat gtcattggag aagtggtcaa actttcccga tcagggcggc
    41761 attatctcgg gctttgccca tttcataagg aaaagacacc ctcttttaat gttgttgaag
    41821 acagacaatt ttttcactgc tttggctgtg gaaaatcagg ggatgttttt aaatttattg
    41881 aggaataccg ccaagtcccc ttcttagaaa gtgttcagat tattgccgat aagactggta
    41941 tgtcgcttaa tataccgcca agtcaggcag tacttgctag ccaacacaag caccctaatc
    42001 acgctttgat gacacttcat gaggatgctg ctaaatttta ccatgcagtt ttgatgacca
    42061 ctaccattgg tcaagaagct aggaagtacc tttaccagag aggcttggat gaccaattaa
    42121 ttgagcattt caatattggt ttagccccag atgagtcaga ttatctttat caagctcttt
    42181 ctaaaaaata cgaggaaggt caattggttg cttcaggatt gtttcacttg tccgatcaat
    42241 ccaataccat ttacgacgcc tttcgaaatc gtatcatgtt tcccttatca gatgaccgag
    42301 ggcatattat tgccttttca ggacgtatct ggacggcagc tgatatggaa aagagacagg
    42361 caaagtataa aaattcaaga ggaacagttc tttttaacaa atcttatgaa ttgtatcatc
    42421 tggacaaggc aaggcctgtt attgccaaaa cccatgaagt gtttctaatg gaagggttta
    42481 tggacgtgat tgccgcttac cgttccggct atgaaaatgc tgttgcttca atggggacgg
    42541 cattgactca agaacatgtc aatcacctta agcaagtcac taaaaaagtt gttttgattt
    42601 atgatggtga cgatgctgga caacatgcta ttgcaaaatc actagaattg cttaaagatt
    42661 ttgttgtcga aattgtcaga atccccaata aaatggatcc tgacgaattt gtacaacggc
    42721 attccccaga agcatttgca gatttgctta agcagtcacg gatcagtagt gttgaatttt
    42781 ttattgatta cctaaaacct actaatgtag acaatttgca atcacaaatt gtttatgtgg
    42841 agaaaatggc accattgatt gctcaatcac catccatcac agctcaacat tcgtatatta
    42901 acaagatttc tgatttgttg ccaaactttg actattttca agtagaacaa tcagtaaatg
    42961 cattaaggat tcaagatagg caaaaacatc aaggtcaaat agctcaagcc gtcagcaatc
    43021 ttgtgacctt accaatgcca aaaagtttga cagctattgc taagacagaa agtcatctca
    43081 tgcatcggct cttacatcat gactatttat taaatgaatt tcgacatcgt gatgattttt
    43141 attttgatac ctctacctta gaattacttt atcaacggct gaagcaacaa ggacacatta
    43201 catcttatga tttgtcagag atgtcagagg aagttaaccg tgcttattac aatgttttag
    43261 aagaaaacct tcccaaagaa gtagctcttg gtgagattga tgatatttta tccaaacgtg
    43321 ccaaactttt agcagagcgc gatcttcaca aacaagggaa aaaagttaga gaatctagta
    43381 acaaaggcga tcatcaagcg gctctagaag tactagaaca ttttattgcg cagaaacgaa
    43441 aaatggaata gaggaaatta tgacaaaaca aaaagaaata acaactttta acgttcaagt
    43501 tgcggagttt attcgccatc acaaaaaaga aggaacagcg attgatgatg acgtgaccga
    43561 aaaacttgtc attccatttg ctttggatgc tgatcagatt gatgacttac ttgagcggtt
    43621 aacagatggt ggtatctcga ttacggataa agaaggtaac ccatcatcaa aatacattgt
    43681 tgaagaacca aaaccagaag aattaactga tgaagaatta attggtagta attcagctaa
    43741 agtaaacgac cctgtccgca tgtacctcaa agaaattggt gtggtaccgc ttttaacaag
    43801 tgaagaggaa aaagaattgg ctgttgcggt tgccaaggga gatttaatgg ctaaacaacg
    43861 tttaacggaa gcaaaccttc gtcttgttgt ctcaattgca aaacgttatg ttggacgtgg
    43921 aatgcaattt cttgatttaa ttcaagaagg taacatggga ctcatgaaag ctgttgataa
    43981 atttgattat tcaaaaggat tcaaattctc aacttatgca acatggtgga ttcgtcaagc
    44041 tataacacgc gcaattgcag atcaagcacg tacgattcgt atccctgttc atatggttga
    44101 aaccattaat aaattggttc gtgaacaacg taaccttctt caagaacttg gtcaagatcc
    44161 aacgccagaa caaatcgcag aacgtatgga aatgactcca gacaaggttc gtgaaattct
    44221 aaaaattgct caagaacctg tttctttaga aacaccaatt ggggaagaag atgatagtca
    44281 cttaggtgat tttatcgaag atgaagttat tgaaaatcca gtagattata cgacgcgtgt
    44341 tgttcttcgt gagcaattgg atgaagtttt agatacgctt actgaccgtg aagagaacgt
    44401 tcttcgccta cgctttggcc ttgacgatgg taaaatgcgt acgttagagg acgtaggtaa
    44461 agtctttaat gttactcgtg agcgcattcg acagattgaa gctaaagccc ttagaaaact
    44521 tcgccatcct agtcgtagta aacaattaag agactttata gaggactaaa atcgtccagt
    44581 ggacgatttt aggtcgttcc tttgaaataa gaaaggagcg aaaatcctaa gtggcactta
    44641 tcagcggtac acctacaaat tagaaatcgg accgaatgtg gtgggtattt ttaagggtag
    44701 acttgatatc ttaaacaagc ccagaaggca attcctctaa ataggcaaag ctttagtggt
    44761 ttttttactt atctacgaca tattcaaaaa atgaaaggaa agccatgtct gatacaccaa
    44821 aatatacaca agatcaggtg atagctatca agaatagaat tcttgaagct ttagaaactg
    44881 ttattgatcc cgagctaggt attgatgttg ttaatctagg cttgatttat gaaattcggt
    44941 ttaatgataa cggttataca gagattgata tgacactcac aacaatgggt tgtcctttgg
    45001 cagacttgtt gacagattac atccatgatg ccctgcaaga tgtgccagaa gtcactaaga
    45061 ctgaggtcaa attagtctgg taccctgctt ggacggttga taaaatgagc cgctatgcta
    45121 ggattgcgct gggtattcgc taatcattga tagtaaaggg atgaaatatt cccttttttg
    45181 atgtagaata aaaggaaata caggtgaaag cctttggtta atgttagaga acactaagat
    45241 actgagaaaa gtgttctacc tatggcaaaa aggagaactg atgattttaa ttacaggaag
    45301 caatggtcaa ttagggacag aacttcgata cttattagat gaacgaggtg ttgattatgt
    45361 agccgttgat gtcgcagaaa tggacatcac aaatgaagac aaagtcgaag ctgtttttgc
    45421 gcaggtcaag ccaacattgg tctatcattg tgctgcttat acggcagttg atgcagcaga
    45481 agacgaagga aaagccttga atgaggctat taatgtaaca ggctcagaaa atattgccaa
    45541 ggcttgtgga aaatatgggg ctacccttgt ttacatttca acagactacg tatttgatgg
    45601 caataaacca gtcggtcaag aatgggtaga aacagatcat ccagacccta agacagaata
    45661 tggccgtaca aaacgtttag gagaactagc tgttgaacga tacgcagagc atttttatat
    45721 tatccgtact gcttgggtat ttggaaatta tggtaaaaac tttgtcttta ccatggagca
    45781 gttagcagaa aatcactccc gtttgactgt tgtcaatgac caacacggtc ggccaacgtg
    45841 gacaaggacc ttggcagaat tcatgtgtta tttgacagag aatcaaaaag cctttggtta
    45901 ctatcacttg tcaaatgatg ctaaggaaga caccacttgg tatgattttg ccaaagaaat
    45961 cttaaaagac aaggctgttg aagtggtgcc agttgattca tcagctttcc cagcaaaagc
    46021 caaacgtcct ttaaattcaa ccatgaatct tgataaggca aaagcaacag ggtttgttat
    46081 tccaacatgg caagaagcct tgaaggcatt ttaccaacaa ggactgaaaa agtaagtatt
    46141 ctaaaaagag ttggctttct aaggccaact ctttttcatg ggtttaaggt cgcattagcc
    46201 ttctaattgt ggtataatat cactgattat attttagaat ggggtagtat gcaatgcagg
    46261 atgtttttat cattggtagc agagggttac cagcgaaata cggtggcttt gaaacctttg
    46321 tcgaagagtt gattagtcat caatcatcta aaaacattcg ttatcatgtt gcttgtttaa
    46381 gcgatacgaa gcataaggtt cattttgatt ataagggggc agattgcttt taccttaatc
    46441 ccccaaaact tggtcctgct agagttattg cttatgatat gatggcaatt acctatgccc
    46501 tgtcttatag cgaccaacac cagattcaga accctatttt ttatgtgttg ggcaatactg
    46561 taggcgcttt tattgcgcca tttgtgaagc agattcacaa tcgaggtgga cgctttttta
    46621 tcaatccaga cgggttagag tggaaacggt ctaaatggtc aagaccagtg caggcctacc
    46681 tgaagttttc cgaaaagcaa atgactagac aggctgattt ggtcatttca gataatattg
    46741 gcattgaccg ctaccttaaa caagtttatc cttggtctaa aacatgtttt attgcttatg
    46801 gaacgcagac acaaccttca cgtttggcaa cagcagatag caaggtcaga gcttattttc
    46861 aaacctttga tattagagaa aaggattact atctcatttt aggacgcttt gttcctgaaa
    46921 ataattacga aaccgctatt aaagaattta tggcttcctc aactaagcgt gatttagtga
    46981 ttatttgtaa tcatgaaggc aatgcttact ttaagcaatt acttgctgag acagagtgtg
    47041 ataaagaccc acgcattaaa tttgttggta ccctttatga caaagaacta ttagcctaca
    47101 ttcgagaaca ggcttatgcc tatatccatg gtcatgaggt aggagggact aatccaggcc
    47161 ttctagaagc actagcccat accaatctta atttggtttt aggagttgat tttaaccagt
    47221 cggtggctaa gtctgctgcg ctttattgga ccaagcaaaa agggcaatta gcagagctga
    47281 ttaaccaagt tgatgcaggt tttgatagtg atcatctggg caaagaagcc aaagctatta
    47341 ttcaagaaca ttacacttgg gaaaaaattg taggggagta cgaggcttta tttttaaatg
    47401 aacattaata ttttactatc cacctacaat ggagaacgct tcttagcaga acaaattcaa
    47461 agtatccaaa ggcaaacagt taacgactgg accttattga ttagagatga tggttcaact
    47521 gatggcaccc aggatattat tcgcacattt gtcaaggaag acaaacgaat tcagtggatc
    47581 aatgaggggc agacagaaaa tctgggagtt attaagaatt tttacaccct cttaaagcac
    47641 caaaaagcag atgtctattt tttcagtgac caagatgata tatggttaga caataaactg
    47701 gaagtgacct tattggaggc tcaaaaacat gaaatgacag ctcctttatt ggtttataca
    47761 gacctcaaag tggtaaccca acatttagct gtttgccatg acagtatgat taagacccaa
    47821 tctggtcatg caaacacaag cctacttcaa gaattaaccg aaaataccgt aacaggcggc
    47881 acaatgatga ttactcatgc tctggctgag gaatggacca cttgtgacgg tttattgatg
    47941 catgactggt atttagcttt actagcttct gctattggga aattagttta ccttgatatt
    48001 ccaacagaat tataccgtca gcacgatgct aacgtgttgg gagctagaac ttggtctaaa
    48061 cgcatgaaaa attggttaac cccccatcat ttagtcaaca aatattggtg gttgattact
    48121 tcaagccaaa aacaggctca attactatta gatttaccat taaaaccaaa tgaccatgaa
    48181 ttggtaacgg cctatgtttc tttattggat atgcctttta ccaaacgctt agctaccttg
    48241 aaaaggtacg gttttagaaa aaatcgcatc tttcacacct ttatttttcg tagtttagtt
    48301 gttaccttat ttggttacag gagaaagtaa gaatgaattt tttaacaaag aaaaaccgta
    48361 ttttactgag agaaatggta aaaacggatt ttaaattacg ctatcaaggg agcgcaattg
    48421 gctatctatg gtctatctta aaaccgctta tgatgtttac gattatgtac ttggtattta
    48481 ttcgttttct tcgcctgggt ggaaatgtac ctcattttcc agtagcgctt ttattggcaa
    48541 atgtcatctg gtcttttttt tcagaagcaa ctagcatggg aatggtatct attgtatctc
    48601 ggggagactt gttgcgaaaa ttgaactttt ctaagcacat cattgttttt tcggcagtgt
    48661 taggagcttt aattaatttt cttattaatt tggttgttgt tttaattttt gcgttgataa
    48721 atggtgtgac tatatcaggg tatgcttatc tctctctttt tctttttata gaattagttg
    48781 ttttagtgct tggaattgca ttgttattgt cgaatgtctt tgtttattat cgtgacttag
    48841 ctcaagtctg ggaagtacta ttacaagcag gtatgtatgc cactccaatc atttatccga
    48901 tcacttttgt tttagatagc caccctttgg cggcaaagtt gttgatgcta aatccagtag
    48961 cacaaatgat tcaagatttt cgttatttat tgattgacag ggccaacgta acgatttggc
    49021 agatgtcaac caattggttt tacattgtta ttccatattt agtaccattt gttatattat
    49081 ttattggcat ctttgtcttt aagaaaaatg ccgatagatt tgcggagatt atttaatgat
    49141 taatagagaa attgcagtaa aagtacagca tgttagtaaa acgtttaaac tgcctacaga
    49201 agcaactaaa agttttcgca cgactctggt taatcgccta agagggatta aaggatttac
    49261 tgaacaacat gtgctaaaag atattaactt tgatgtttat aaaggcgatt tttttggaat
    49321 tgttgggcgt aacggctcag gaaaatcaac gctccttaaa attatttccc agatctatgt
    49381 tccagaaaaa gggcaggtta cagtagatgg gaagatggtt tcttttatag agcttggagt
    49441 gggattcaat ccagaattaa caggacgaga aaacgtctat atgaacggcg ccatgctggg
    49501 atttaccaaa gacgaagttg atgatatgta caatgatatt gttgattttg cagagttgca
    49561 tcattttatg aatcaaaaat taaaaaatta ttcttctggc atgcaggtac gtttagcatt
    49621 ttcagtggct attaaagccc aaggtgacgt tcttatttta gatgaggtgc ttgctgtagg
    49681 agatgaagct tttcagcgaa aatgtaatga ttattttatg gaaagaaaag acagtggtaa
    49741 gacgactatt ttagtgacac atgatatggg agctgttaag aagtattgta accgtgcagt
    49801 tcttattgaa gatggtcttg ttaaagcata tggagaacca tttgatgttg ctaatcagta
    49861 tagtgtagat aatacagaga cagctgagga tgcaatgaat gctgaaaaaa tatctgtatc
    49921 tgatattgcc aaagatttga aagtgtcatt aatctcaaat ccaagaataa caccaaatga
    49981 cacaatcaca tttgaagttt cttatgaagt tttaaaagat gattttacct acattgcctt
    50041 ttctttaacg gatattgata gaaacatttg ggtttacaac gacaattctt tagattatcc
    50101 aacacaaggt ataggtagaa aatgcatttc ctaccaatgt caactatctc aacttaatga
    50161 tataaaacta aaattagaag taactgtccg agataagaac ggtcagatgc tactcttttc
    50221 aacagcagaa caatcacccc agatagtgat tcaaagaaac gatattgatc aagatgatct
    50281 gtcagctcta gattcagcaa gtggcttgta tcaacgtaat gggaagtggg tttttcatta
    50341 atgagtaata gctagaaggg aatttatgta taaagtttca attatttgca ccaattataa
    50401 caaagctcct tggatatctg atgcacttga cagtttttta agccaagtga cagattttga
    50461 ggttgaaatt attgttattg atgatgcttc tacagatgac tcacgagaga ttttaaagag
    50521 ttatcaaaaa aagtcttcag gaaaaattaa attactcttt aacgaaacta atattggaat
    50581 aacaaagact tggataaaag catgccttta tgcaaaaggc aaatatattg ctagatgtga
    50641 tggtgatgat tactggacgg atagttttaa actccaaaaa caagttgatg tcttagaagc
    50701 ttccaaacgg tcacgatggt gtaatactga ttttgacttt gtaaatagtc aaggcgactt
    50761 attatatgct aatgcttttt catctggtca tacacctttg acagatactt acgaaaaagt
    50821 tttagcctta aaagggatga cgatggcatc gacatggtta gttgatgctg atttaatgag
    50881 acaagtaaac caaaaaatca atgtagatac accagacgat acttttgata ttcaactaga
    50941 gttatttcaa ctgactcaac tgacctatat taaagactca acgacgattt atcgcatgac
    51001 aaccgattct gattcaagac ctactgatac accaaaaatg atttatcgta ttcaaaaact
    51061 acttgatact cagttaaatt acttaaaaaa gtataatcag gtagatacaa aagaagtgtc
    51121 tgaactatta ttacaacaag atgctaagca agaaatacga attcatgagt tgagttgctt
    51181 tattcaagaa ttacaacaaa ctatcgtaga taaaacaaag cagcaagaaa cacgtgaagt
    51241 ggagttgcaa aatgtcatag aagaacaaaa aaatcaacta tctgaattaa gacaacaata
    51301 ccatgccatt attaattcac gtcaatggaa atacacgtct aagctcattg cttttattag
    51361 gagaaaaaaa tgaatcgtat tttattatat gttcacttca acaaatacaa taaaataagt
    51421 gcacatgttt actatcaatt ggaacaaatg agatcactgt tttctaagat tgtttttatc
    51481 tcaaatagta aagtgagtca cgaagattta aaacgtctca aaaaccactg tcttattgat
    51541 gagtttttgc aacgcaaaaa taaaggtttt gatttttctg catggcacga tggcttgatt
    51601 attatgggat ttgacaagtt ggaagagttt gactcattga cgattatgaa cgatacttgt
    51661 tttggtccta tttgggagat ggctccttat tttgaaaatt ttgaagaaaa agagacagtt
    51721 gacttttggg gaattactaa taatagaggt acaaaagctt ttaaagaaca tgtccaaagt
    51781 tattttatga cgtttaaaaa tcaagtcatt caaaacaaag tttttcaaca attttggcaa
    51841 tcgataatag aatatgaaaa cgttcaagaa gtgattcagc attatgaaac gcaattaaca
    51901 tccattctct taaatgaagg ctttagttat cagacggtct ttgatactag aaaagctgag
    51961 tcgtcattca tgccacatcc ggatttttca tattataatc caacagcaat tttaaaacac
    52021 catgtgcctt ttataaaagt aaaagctatt gatgctaacc agcatatcgc tccttactta
    52081 ttgaatctga tacgagaaac aaccaattat cctatagatc ttattgtttc acatatgtcg
    52141 caaatctctt tgccagatac taagtacctt ttatctcaaa aatacctaaa ctgccaacgg
    52201 ttagcaaaac aaacttgtca aaaggtagct gttcatttac atgtttttta cgttgatttg
    52261 ctagatgaat ttttaacagc tttcgaaaac tggaacttcc attatgatct ttttattaca
    52321 acagatagtg atatcaaaag aaaagagatc aaagaaatac ttcaaagaaa aggtaaaact
    52381 gctgatatac gcgttacggg aaatagagga agagatattt atccaatgtt attactaaaa
    52441 gataaacttt ctcaatatga ttatattggt catttccata cgaaaaaatc aaaagaagct
    52501 gatttttggg caggagaatc ttggcgaaaa gaattgattg atatgctcgt gaaaccagca
    52561 gatagtattc ttagcgcttt tgagacagat gatattggta ttataatcgc agatattcca
    52621 agttttttta gatttaataa gattgtcaat gcttggaatg agcatttaat cgctcaagaa
    52681 atgatgtctt tgtggagaaa aatggatgtt aaaaaacaaa ttgattttca agctatggat
    52741 acatttgtta tgagttatgg aacatttgta tggtttaaat acgatgctct aaaatcactt
    52801 tttgatttag aattaactca aaatgatatt ccaagtgaac ctttaccaca aaactctata
    52861 ttacatgcga ttgagcggtt acttgtctat atagcgtggg gggattctta tgattttagg
    52921 attgttaaaa atccctatga gttaacacct tttattgaca ataaactgtt aaatttacgt
    52981 gaagatgaag gagctcatac ctacgttaac tttaatcaaa tgggcggtat caaaggagca
    53041 ttgaaatata ttatcgttgg tcccgctaaa gcaatgaagt atatattctt gcgtttaatg
    53101 gagaaactta aatgattaaa gacacatttt taaaaaccaa ttggttaaat attagtcacc
    53161 atattatcct tcttgttttc ggtttttatt tcagttttta cagtttggcg aaagaactag
    53221 taagctccac ggcacaaccg gtaaactatt atgctcattt actaaatgtt tcttttgtgg
    53281 gatatattat atcactgatt ggattatctt attatttgag tcgccaagtt agtcgacagt
    53341 tgtttttgaa aactagtttt attgtgatat cttatctaat tgtcagctat tgggtacaaa
    53401 taacacagca cctgaatgat aaacggtttg atatctggtc attaactaaa aatcaatttt
    53461 atcaatttca agctctacct tctttactca ttattttagt gatggccact ttaataaaaa
    53521 tattggtagc atattttgca atagaaaaag atagatttgg gctattaggc tatcaaggta
    53581 atactttttc tgtagctctg attttagcag ttgtgccaat taatgacata catctgttaa
    53641 aactaataag ttctcgattt tctgaattag taacagcagg taatagccaa attgcactgt
    53701 taaaaataag tggactgttg atagttttac ttgtcatatt tgcaacaatc atatacgtgg
    53761 ttttaaatgc tctaaaacac cttaagtcaa ataaaccttc attttcagta gcagctacta
    53821 ctagtttgtt tttagcatta gtttttaact atacgttcca gtatggagta aaaggtgatg
    53881 aagcattgct aggatattat gttttccctg gagctactct ttttcagata gtagctatta
    53941 cactagttgc tcttttagca tacgtgataa cgaatagata ttggccaact accttctttt
    54001 tgcttattct gggaacaatt atttctgttg ttaatgattt aaaagaatca atgagaagcg
    54061 agccgttatt agtaactgat tttgtttggt tacaagaatt aggtttagtg acaagctttg
    54121 ttaaaaaatc ggtgattgta gaaatggttg taggacttgc tatttgtatt gtggtagctt
    54181 ggtatctaca tggccgagtt ttagcaggga aattatttat gagccctgtc aaacgggcaa
    54241 gtgctgtatt aggtttattt attgtatctt gtagtatgtt aataccattt tcttatgaaa
    54301 aagaaggtaa aatattatct ggtcttccga ttatttcggc tttaaataat gataatgaca
    54361 taaactggtt aggtttttca acaaatgcta ggtacaaatc tttagcatat gtttggacaa
    54421 gacaggtgac caagaaaata atggaaaaac cgacaaatta tagccaagaa acaatagcga
    54481 gtatcgctca gaagtaccaa aaattagcag aagatattaa taaagacaga aaaaataata
    54541 ttgctgacca aacggttatt tatcttttaa gtgaaagctt gtcagatcct gatagagtat
    54601 caaatgttac tgttagccac gatgttttac ctaatatcaa ggcaatcaaa aatagcacaa
    54661 ctgcgggact catgcagtca gactcctacg ggggtggaac ggctaacatg gagtttcaaa
    54721 cgttaacaag cttacctttt tataattttt cttcttcagt atctgttctt tattcagaag
    54781 tctttcctaa aatggccaaa cctcatacga ttagtgagtt ttaccaagga aaaaatcgta
    54841 ttgcgatgca tcctgctagt gctaacaatt ttaatagaaa aacagtttat agtaatttag
    54901 gtttttccaa attcttagct ctatcgggtt ctaaggataa gtttaagaac attgaaaatg
    54961 tcggtttatt gactagcgat aaaactgtct ataataatat tttatcttta attaatccta
    55021 gtgaaagcca atttttctca gttattacaa tgcaaaatca tattccttgg tcatccgatt
    55081 atcctgaaga aattgttgct gaaggaaaaa atttcacgga agaagaaaat cacaacctaa
    55141 caagttatgc tcggttatta tcgtttactg ataaggaaac aagagcattt ttagaaaaat
    55201 taacacaaat taacaagcct atcacagtgg tgttttacgg agatcattta cccggtttat
    55261 atcctgatag tgcttttaac aagcatattg aaaataaata ccttactgat tattttattt
    55321 ggagtaatgg tactaacgag aaaaaaaatc atccgcttat caactcaagt gattttactg
    55381 cagctttatt tgagcatact gattcaaaag tatcacctta ctatgctttg ttaacagagg
    55441 tactgaataa agctagtgtc gataaatcac cagatagtcc tgaagttaaa gctattcaga
    55501 atgatttaaa aaatatccaa tacgatgtga ctataggaaa aggttacctt ttgaaacaca
    55561 aaactttttt taagatatca cgttaagaaa aatgctaggc tgtccgagta taggcaagca
    55621 tcaaggtttg gtaatttgct caaatgattg tcaacagagt gtctaggacc aggtttaaaa
    55681 gattataatt cttaaggtct tattcgttta taaaaaatga atactctttt aaaatcttaa
    55741 ttgaaatgaa taggagaagt tttcgtgaaa aagttaatca ttattcctgc ttacaatgaa
    55801 agcagtaata ttgtcaatac tatacgtact attgaatcag atgccccgga ttttgactat
    55861 atcattattg atgattgctc aacggataat acgttagcaa tatgtcaaaa acaggggttc
    55921 aatgttattt ctttgcccat taacctggga attggcggtg cggtgcaaac tggctatcgt
    55981 tatgcacaaa gatgtggata tgacgttgca gttcaagtag atggagatgg tcagcacaat
    56041 ccatgctatt tggaaaaaat ggttgaggta ttagttcaat cttcagtaaa tatggtaatt
    56101 ggatcacgat ttatcacaaa agaagggttt cagtcatcat ttgctcgacg tatcggcata
    56161 aagtatttta cttggcttat tgcgctacta acaggaaaaa aaataacaga tgcaacgtca
    56221 ggtctaaggt taattgaccg ttcattgatt gaacgttttg ctaatcatta tccagatgat
    56281 tatcctgaac ctgaaacagt tgttgatgta ttggttagtc attttaaagt gaaagaaatt
    56341 cctgttgtaa tgaatgagcg acaaggcggt gtgtcatcta tctcgttgac gaaatcggtc
    56401 tattatatga ttaaagtgac tttagctatt ttagttgtta gattgaaagg aaatcgttaa
    56461 aatgacggta acagccagtt tatttataag ttttattgta ttaacctttg ttttcttttt
    56521 gattaactta atcaaaaaag ataaactagc gattaagtac tctttattgt ggtttatttt
    56581 agctttatta attttactat ttacgtggtt acctaacata ttaaataaaa tgtctcactt
    56641 cctgggtatt cattcaccaa ccaatatgtt attcttttta ggtttttgtt tgagtttagc
    56701 tattattttt tcactgacta ataatatttc acttcaaaat gataaagtaa aacgtctgac
    56761 ccaagaagtg gcccttatga aaaaagagaa aaccaatgat taatccttca aaacaaaacc
    56821 aaacgatttt tttatggaat atgttaggaa gtttatcaac agctgtaata tcagttatat
    56881 tacttatggt ggttactagg ttactaactt cggctgattc agatatttac gcctttgcct
    56941 attcttttgc taatatgatg gtagttgttg gactttttca ggttcgtaat tatcaagcaa
    57001 cagatattaa tgaaaaatat tcctttagtc agtacttagt ggcaagactg atgacttgtt
    57061 tattaatgtt agccataaca gtaatttatt taacgttaac taagacagat agctacaaga
    57121 gtacaattgt ctttctagtc tgtttctata gatcgacaga tgctttttcg gatttatatc
    57181 agggaatgtt ccaacaacat gaacggctgg atattgcagg taaatcgcta gcctacagaa
    57241 atactcttat ttttatggtg tacacagcaa taatattata ttccaaaaat cttactttag
    57301 cattagtagc tgtctgtata gtttcattag t
//
LOCUS       DAUGQX010000003        54757 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUGQX010000003 DAUGQX010000000
VERSION     DAUGQX010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54757
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.003"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            193..1428
                     /gene="arcA"
                     /locus_tag="VIA51_000140"
     CDS             193..1428
                     /gene="arcA"
                     /locus_tag="VIA51_000140"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEQ8682120.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1528..1956
                     /locus_tag="VIA51_000141"
     CDS             1528..1956
                     /locus_tag="VIA51_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8682121.1"
                     /translation="MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            1996..3009
                     /gene="argF"
                     /locus_tag="VIA51_000142"
     CDS             1996..3009
                     /gene="argF"
                     /locus_tag="VIA51_000142"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEQ8682122.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3179..4672
                     /locus_tag="VIA51_000143"
     CDS             3179..4672
                     /locus_tag="VIA51_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEQ8682123.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4689..6020
                     /locus_tag="VIA51_000144"
     CDS             4689..6020
                     /locus_tag="VIA51_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEQ8682124.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPEGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            6040..6990
                     /gene="arcC"
                     /locus_tag="VIA51_000145"
     CDS             6040..6990
                     /gene="arcC"
                     /locus_tag="VIA51_000145"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEQ8682125.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7303..8295
                     /locus_tag="VIA51_000146"
     CDS             7303..8295
                     /locus_tag="VIA51_000146"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEQ8682126.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLGF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKQHIGEVQTSVWPQEVRDSYDNIL"
     gene            8418..8957
                     /gene="rsmD"
                     /locus_tag="VIA51_000147"
     CDS             8418..8957
                     /gene="rsmD"
                     /locus_tag="VIA51_000147"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEQ8682127.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8947..9438
                     /gene="coaD"
                     /locus_tag="VIA51_000148"
     CDS             8947..9438
                     /gene="coaD"
                     /locus_tag="VIA51_000148"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEQ8682128.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9425..10462
                     /locus_tag="VIA51_000149"
     CDS             9425..10462
                     /locus_tag="VIA51_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEQ8682129.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10819..10899
                     /locus_tag="VIA51_000150"
                     /pseudo
     CDS             10819..10899
                     /locus_tag="VIA51_000150"
                     /inference="COORDINATES: protein motif:HMM:NF019884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10876..11852
                     /locus_tag="VIA51_000151"
                     /pseudo
     CDS             10876..11852
                     /locus_tag="VIA51_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            12276..12920
                     /locus_tag="VIA51_000152"
     CDS             12276..12920
                     /locus_tag="VIA51_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEQ8682130.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRASKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12924..14003
                     /gene="rlmN"
                     /locus_tag="VIA51_000153"
     CDS             12924..14003
                     /gene="rlmN"
                     /locus_tag="VIA51_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEQ8682131.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(14085..14711)
                     /locus_tag="VIA51_000154"
     CDS             complement(14085..14711)
                     /locus_tag="VIA51_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEQ8682132.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEIGLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            14939..15466
                     /locus_tag="VIA51_000155"
     CDS             14939..15466
                     /locus_tag="VIA51_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEQ8682133.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            15608..15811
                     /locus_tag="VIA51_000156"
     CDS             15608..15811
                     /locus_tag="VIA51_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEQ8682134.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            15816..16787
                     /locus_tag="VIA51_000157"
     CDS             15816..16787
                     /locus_tag="VIA51_000157"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEQ8682135.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            16797..17186
                     /locus_tag="VIA51_000158"
     CDS             16797..17186
                     /locus_tag="VIA51_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEQ8682136.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRTKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            17369..19210
                     /gene="typA"
                     /locus_tag="VIA51_000159"
     CDS             17369..19210
                     /gene="typA"
                     /locus_tag="VIA51_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEQ8682137.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSVTKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            19332..19583
                     /locus_tag="VIA51_000160"
     CDS             19332..19583
                     /locus_tag="VIA51_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEQ8682138.1"
                     /translation="MFYLIMAVSIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            19953..21311
                     /locus_tag="VIA51_000161"
     CDS             19953..21311
                     /locus_tag="VIA51_000161"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEQ8682139.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            21311..22393
                     /locus_tag="VIA51_000162"
     CDS             21311..22393
                     /locus_tag="VIA51_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEQ8682140.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            22394..23542
                     /locus_tag="VIA51_000163"
     CDS             22394..23542
                     /locus_tag="VIA51_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEQ8682141.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMHDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQTPPSPETVLEQAHG"
     gene            23754..25118
                     /gene="ftsA"
                     /locus_tag="VIA51_000164"
     CDS             23754..25118
                     /gene="ftsA"
                     /locus_tag="VIA51_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEQ8682142.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            25142..26461
                     /gene="ftsZ"
                     /locus_tag="VIA51_000165"
     CDS             25142..26461
                     /gene="ftsZ"
                     /locus_tag="VIA51_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEQ8682143.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            26464..27135
                     /locus_tag="VIA51_000166"
     CDS             26464..27135
                     /locus_tag="VIA51_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEQ8682144.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIGEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            27147..27803
                     /locus_tag="VIA51_000167"
     CDS             27147..27803
                     /locus_tag="VIA51_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEQ8682145.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSSIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            27808..28062
                     /locus_tag="VIA51_000168"
     CDS             27808..28062
                     /locus_tag="VIA51_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEQ8682146.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            28062..28853
                     /locus_tag="VIA51_000169"
     CDS             28062..28853
                     /locus_tag="VIA51_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEQ8682147.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRVA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            28863..29621
                     /locus_tag="VIA51_000170"
     CDS             28863..29621
                     /locus_tag="VIA51_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEQ8682148.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            29894..32695
                     /locus_tag="VIA51_000171"
     CDS             29894..32695
                     /locus_tag="VIA51_000171"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEQ8682149.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNTKENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGTVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEYESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGVAFIVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(32960..33262)
                     /locus_tag="VIA51_000172"
     CDS             complement(32960..33262)
                     /locus_tag="VIA51_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEQ8682150.1"
                     /translation="MRLINTTSSHPELIKNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(33313..33768)
                     /locus_tag="VIA51_000173"
     CDS             complement(33313..33768)
                     /locus_tag="VIA51_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8682151.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(33896..36178)
                     /locus_tag="VIA51_000174"
     CDS             complement(33896..36178)
                     /locus_tag="VIA51_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8682152.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYIGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            36476..36706
                     /locus_tag="VIA51_000175"
     CDS             36476..36706
                     /locus_tag="VIA51_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEQ8682153.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            36833..37519
                     /locus_tag="VIA51_000176"
     CDS             36833..37519
                     /locus_tag="VIA51_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8682154.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYFPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            37519..38253
                     /locus_tag="VIA51_000177"
     CDS             37519..38253
                     /locus_tag="VIA51_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682155.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVMFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            38402..39811
                     /locus_tag="VIA51_000178"
     CDS             38402..39811
                     /locus_tag="VIA51_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEQ8682156.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKNLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            39989..41683
                     /locus_tag="VIA51_000179"
     CDS             39989..41683
                     /locus_tag="VIA51_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8682157.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            41891..42745
                     /locus_tag="VIA51_000180"
     CDS             41891..42745
                     /locus_tag="VIA51_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEQ8682158.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            42898..44238
                     /locus_tag="VIA51_000181"
     CDS             42898..44238
                     /locus_tag="VIA51_000181"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEQ8682159.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            44216..44431
                     /locus_tag="VIA51_000182"
     CDS             44216..44431
                     /locus_tag="VIA51_000182"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEQ8682160.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            44431..45303
                     /locus_tag="VIA51_000183"
     CDS             44431..45303
                     /locus_tag="VIA51_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEQ8682161.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            45296..46123
                     /locus_tag="VIA51_000184"
     CDS             45296..46123
                     /locus_tag="VIA51_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HEQ8682162.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            46110..46580
                     /locus_tag="VIA51_000185"
     CDS             46110..46580
                     /locus_tag="VIA51_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8682163.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            46602..48263
                     /gene="recN"
                     /locus_tag="VIA51_000186"
     CDS             46602..48263
                     /gene="recN"
                     /locus_tag="VIA51_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEQ8682164.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDILNSLTRKYGGNVNDVLDYYDNIVKEY
                     QLLTGDDLSSGDLEAELKSLEKQLVAAASELSVSRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            48435..49376
                     /locus_tag="VIA51_000187"
     CDS             48435..49376
                     /locus_tag="VIA51_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8682165.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLNEL
                     DELDEENEEDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLR
                     SLSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAH
                     YEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYSRKLGMAVAK
                     RKIALPQTGEGFSYYPVLLGLMILGLTPIMIPKKINN"
     gene            49592..50443
                     /locus_tag="VIA51_000188"
     CDS             49592..50443
                     /locus_tag="VIA51_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8682166.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            50436..51278
                     /locus_tag="VIA51_000189"
     CDS             50436..51278
                     /locus_tag="VIA51_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEQ8682167.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            51256..51843
                     /locus_tag="VIA51_000190"
     CDS             51256..51843
                     /locus_tag="VIA51_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEQ8682168.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTEKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            51942..52217
                     /locus_tag="VIA51_000191"
     CDS             51942..52217
                     /locus_tag="VIA51_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEQ8682169.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(52307..53449)
                     /locus_tag="VIA51_000192"
     CDS             complement(52307..53449)
                     /locus_tag="VIA51_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8682170.1"
                     /translation="MWIEETDNGKFKFRENYKDPYTGTWKPVSVTMEKDNSRAYKAAR
                     KILEQKITEKIAQLKASELLFTELLDEWWAFYKKELKRSSVASLRGNIEEIRETFGIG
                     VKVVNIDPKYVQNYLDNLDCSRNKKERNKSMLNLAFDYAVGLDIIQDNPARRAKLPRV
                     KKTLEDWKKAEEKYLEEDEIKPLLKELYRRPSTYRLGLLAEFISLNGCRIGEAVSIEP
                     CNYESKSRILQLHGTFDHTEGYRNGEKTAPKTLASYRETIMTSRELEILQELEFMNEL
                     EKNTNHRYRDMGYLFTTKNGVPIQTNSFNLALKKANERLEDPITKKLTSHIFRHTLIS
                     RLAENNVPLKSIMERVGHADAKTTAQIYTHVTKKMKSSVADIMENY"
     gene            complement(53573..53839)
                     /locus_tag="VIA51_000193"
     CDS             complement(53573..53839)
                     /locus_tag="VIA51_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEQ8682171.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSRGFGGGDRIQATMVFEKIK"
     gene            complement(53851..54231)
                     /locus_tag="VIA51_000194"
     CDS             complement(53851..54231)
                     /locus_tag="VIA51_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEQ8682172.1"
                     /translation="MTIEEILDFHNVELAYFDNELWPRPGIYIDEIKVVFVNRALSDE
                     SKKKVIFHELGHIEHDSGQYQRRHEEFELQANRHMIRCLLEDEFDKVEDKHEFNYLSF
                     MQRHNLKTTTDEVMVIDEYYTLIG"
     gene            complement(54235..54582)
                     /locus_tag="VIA51_000195"
     CDS             complement(54235..54582)
                     /locus_tag="VIA51_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682173.1"
                     /translation="MFITFERIKELAKKQGLSINSLEEKMGYSRNTIYALKRNKPGSE
                     KLQEIADYFHVSTDYLLGRTDNPAIAKDNQEYTSEDLRKMAKNAKTFDGKPLTESDIE
                     AIQNIIEIYLKGR"
BASE COUNT        17287 a         9477 c        11405 g        16588 t
ORIGIN      
        1 aaaaacatac aagtaaacga atacaaatct ataaaaataa aaacaacgct caaaaaatgt
       61 aagcgattac tcaaaatagc tgtgagaaat accctatttt tatctttttt aaggagtaca
      121 ctaggaatat aagcaagagt taagaatctt gacggtgaat tcacaaaaac caattagaaa
      181 gaggtaattc ttatgactgc tcaaacacca attcatgttt attctgaaat tggaaaatta
      241 aaaaaagtgt tgctccacag acccggtaaa gaaattgaaa atcttatgcc agactacttg
      301 gaacgcttgt tgtttgatga tattccattc ttagaggatg cccaaaaaga acatgatgct
      361 tttgcccaag ctttgcgtga cgaaggtatt gaagtcttgt accttgagac cttagctgca
      421 gaatctcttg tcactccaga aattcgcgaa gctttcatcg atgaatacct aagtgaagct
      481 aatatccgtg gaagagctac taaaaaagcc attcgtgaat tgttgatggc tatcgaagac
      541 aatcaagaat tgattgaaaa aaccatggca ggagttcaaa aatctgaact tccagagatc
      601 ccagcatctg aaaaaggctt gactgacttg gttgaatcca attacccatt tgccatcgac
      661 ccaatgccaa acctttattt cacacgggac ccattcgcaa ctatcggtac aggtgtttct
      721 cttaaccaca tgttctcaga aacccgtaac cgtgaaaccc tttatggtaa atacattttc
      781 actcatcacc caatttatgg tggtggcaaa gtgcctatgg tttatgaccg taatgaaacc
      841 actcgcattg aaggtgggga cgaacttgtt ctttcaaaag atgtgcttgc ggttggtatt
      901 tctcaacgta cagatgctgc ttctattgaa aaattgttgg ttaacatctt taaacaaaac
      961 cttggcttca agaaagtatt ggcctttgaa tttgcaaata accgtaaatt tatgcactta
     1021 gacactgtct ttaccatggt tgactatgac aaattcacca ttcacccaga aattgaaggc
     1081 gaccttcgtg tttactctgt cacttacgac aatgaagaac ttcatatcgt tgaagaaaaa
     1141 ggtgatttag cagaacttct tgctgctaac cttggtgttg aaaaagttga ccttatccgt
     1201 tgtggtggtg acaacttagt agcagcaggt cgtgaacaat ggaacgatgg ttctaatacc
     1261 ttgaccatcg caccaggtgt ggttgtggtt tataaccgta acaccattac caatgccatt
     1321 cttgaatcta aaggcttgaa gttgatcaag attcacggaa gtgaattggt tcgcggtcgt
     1381 ggtggacctc gttgtatgtc aatgccattt gaacgtgaag atatttaata agctatggta
     1441 aaggtggtta taggtcagaa gcctttttaa agggcagcta gtgtttatct tcgcttctgt
     1501 gtctttgtcc ttcaatgaaa ttttgtcatg gcagataaat ttgatgccaa tgacgaaaca
     1561 agaacggttt atgcagtcgt ttatgacaat gaccagcccg tttcaacagg acaattttta
     1621 gctgaaacga aaatagaagc acgattgaca cgcattgtaa ccttagcaga ttattgtggt
     1681 tgcggttatg gtgccaaagt cactgaagcg ctcgaaactt ataccagacg agaaggcttt
     1741 taccaactaa ccattcacag tgaactgaca gcacaaacct tttatgaaaa cctaggttat
     1801 cagtcctatg gtcccaagtg tttagaagat ggtgagtatt gtcagtccct tgcaaaaacc
     1861 attcttaaat gggagaagaa tatggacata gcaatgctaa ttgcgattgt tggtggtcta
     1921 ttaggctgct atctctatct cacaaaaaat aattaatcaa aacagattac agttaacact
     1981 cgaaggagac aatagatgac acaagtattt caaggacgta gcttcctagc agaaaaagat
     2041 tttacacgcg ctgaattaga ataccttatt gatttttcag cacatttgaa agatttgaaa
     2101 aaacgtggtg tgcctcatca ctacttagaa ggtaaaaaca ttgccctctt gtttgaaaaa
     2161 acatcaactc gtacgcgtgc agcttttaca acagcagcca ttgacctagg tgctcaccca
     2221 gaatacctcg gtgccaatga catccaactt ggtaaaaaag aatcaacaga agacactgct
     2281 aaagtattgg gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgcatggtt
     2341 gaagaattgg cagaattctc aggtgtgcca gtttggaatg gtttgactga tgaatggcac
     2401 ccaacccaaa tgcttgctga ctatttaaca gtgaaagaaa actttggcaa acttgaaggc
     2461 cttacccttg tttactgtgg tgacgggcgt aataacgttg ccaattccct tcttgtgact
     2521 ggtgctatcc ttggtgttaa tgttcatatc ttctccccaa aagaactttt cccagaagaa
     2581 gagattgtga cattggctga aggctatgct aaagaaagtg gcgctcgtat ccttatcaca
     2641 gaagatgctg acgaagctgt taaaggcgca gacgtgcttt acacagatgt ttgggtatca
     2701 atgggtgaag aagacaaatt caaagaacgt gttgaattgc ttcaaccata tcaagtcaac
     2761 atggaccttg ttcaaaaagc aggaaatgac aagcttatct tcttgcactg cttgccagct
     2821 ttccatgaca caaataccgt ttatggtaaa gacgttgctg aaaaattcgg cgtgaaagaa
     2881 atggaagtca ctgatgaagt cttccgcagc aaatacgctc gtcattttga ccaagctgaa
     2941 aaccgcatgc acactatcaa agcggttatg gcagcaaccc ttggtaacct ctttattcca
     3001 aaagtgtaat aaggactggt actccttaac tcatttcaca tatcaatgtg acccctttaa
     3061 tttaacaatt taactactta aaaacgtact ttaactacat gacaagtcgt tctggttttc
     3121 gcgtccttga ccggaactag aacggcttat ttttatgaaa aggtaagagg taatcattat
     3181 gacagaagaa aaaaaacggg gttttagaat tccttcttct tacaccgttc tttttatcat
     3241 tatagccatc atggcagtgt taacttggtt tattccagct ggcgcctacg aaaccgctaa
     3301 gggcggtggt gttatttcag gaacctacaa aacagtagca tccaatcctc aaggattttt
     3361 tgacatcttg atggctcccg ttcgaggcat gttaggtgtt gaaggcactg atggtgctat
     3421 tcaagtgtct ttctttatct taatggttgg gggcttttta ggagttgtca acaaaacagg
     3481 tgctcttgac acagggattg cgtcagtggt tcgtaaaaac aaaggtagag aaaaaatgct
     3541 gattgctatt ttaatccctt tgtttgctct aggtggaacg acctatggta tgggggaaga
     3601 aaccatggcc ttttacccac ttttaattcc tgttatgatt gcggttggtt ttgacagtat
     3661 tgttgctgta gccattattt tgattggttc tcaaattggg tgtctagcct ccactattaa
     3721 cccatttgca actggtgtag cagctgatgc tgctggtgtc agcattgcag atggaatgat
     3781 ttggcgtgtt atccaatggg ttattcttgt cggcatgtct atttggtttg tttacaatta
     3841 cgctagtaag attgaagaag acccaagtaa atcattggtt gcagacaagg aagaagagca
     3901 taaggaactc ttccagttgc aaaattctgg agaagactta aacaagcgcc aacgaaacgt
     3961 tttgaccatt tttactttga cctttgtcat tatgattctt agtttgattc cgtgggaaga
     4021 ttttggcatc aaattcttta ctaatatcaa tacttggtta accacaatgc ctatcttagg
     4081 gggagttatt gggaaaacca tgggagcatt tggtacttgg tatttcccag aaatcaccat
     4141 gctctttatc atgatgggtg tcttagttgc tattgtttat cgtatgagtg aagaagactt
     4201 ttttagctct tttttgactg gtgcaggtga atttttaggt gttgccatga tctgtgctat
     4261 tgcacgcggt attcaagtta tcatgaatgg tggtatgatt acagccacta tcttacactt
     4321 aggtgaaaca agtctttctg gtttatcttc tcaagttttt gtgatattag cttatatttt
     4381 ctacctccca atgtccttct tgattccatc aacatcagga cttgctgggg ctacaatggg
     4441 aattatggca ccgcttggac aattctcaaa tgtccctgct caccttgtta ttacagcctt
     4501 ccagtcagct tctggaatct taaacatgat ttctccaact tcagcaatcg ttatgggagc
     4561 acttgcgctt ggtcgcgttg accttggtac ttggtggaaa ttcattggta aatttattgt
     4621 aatggtgatg cttgtaagcg tgctattact tgtagttgca acattctttt aacagatagg
     4681 aggttcctat ggaatcctat atcacaccta aacatcaaga ggcctgtgta gctgccatta
     4741 aacagatcgt ttcttaccct tctgtttgtc atgaaggaga aaatggcaca ccttttggac
     4801 aggccattca agatgttctc gaagcaacct tagacttatg tcaaggtctt ggttttcata
     4861 cttatattga tcctgaaggt tactatggct atgctgagtt aggtgaccaa aaagaggtct
     4921 tggctattct ttgccatttg gacgttgttc cagaaggaga tcgtcagtta tggaagacag
     4981 atccttttga ctgtgttgag gcagacggct gtttatttgg tcgaggcact caagacgata
     5041 aagggcctac tatgatggcg ctatttgcca ccaaagcctt gatagatgca ggcgttacct
     5101 ttaataaacg cattcgtttt attttcggaa cagatgaaga aactttgtgg cggtgtatga
     5161 atcgctacaa tgatgtagaa gaacaggcta cctttgggtt tgctcctgat tcaagtttcc
     5221 ctttaaccta tgccgaaaaa ggcctacttc aggcaaaatt agtggggaaa ggttctgata
     5281 aactgtcact tgaaatcgga caagcctaca atgttgttcc tgcaagagcc tcttatcaag
     5341 gtgataagct tgaggcttta caaaaagaac tagataagct tggctttgag tacgtcgtca
     5401 aagagggaga attaacggtt tatggtctcg cccaacatgc taaagatgct cccgatggca
     5461 tcaacgctat gattaggctt gccaaggctt tagtggtcct tgaacctaac aaaacccttg
     5521 attttcttgc taatgtcatt gatgaagatg gcagagcact taatattttt ggcagaatcg
     5581 aagatgaacc ttcaggcaaa ttaagcttta atgccgcagg gcttacctta accaaagaca
     5641 aggcagaaat tcgcctagat attcggattc cagttttggc agataaggaa aaattagtcc
     5701 aacaattaag ccaaaaagca caagaatacg gcctaaccta tgaagaattt gattatttgg
     5761 ccccattata tgtgccatta gacagtgaat tggtaacaac cttgttatct gtctatcgga
     5821 aaaaaacagg tgatcaaagc cctgcccaat catcaggagg ggcaaccttt gctagaacaa
     5881 tgaagaattg tgttgccttt ggtgcccttt tccctgatgc tgttcaaacg gaacaccaag
     5941 aaaatgaaca tattgtttta gcggatgctt accgcgctat ggatatttat gcggaagcta
     6001 tttaccgact aacgcgataa caagatatga ggagtaatta tgacgaaaca aaaaatcgta
     6061 gtcgcacttg gaggaaatgc tattctttca acagatgcgt cagcaaaagc acaacaagaa
     6121 gccttgattt ccacatcaaa atcactggtt aaattaatta aagaaggtca tgaagtcatc
     6181 gtgacccacg gcaatggccc acaagttggt aatctcttgt tacaacaagc agcagcagat
     6241 tctgaaaaga atccggctat gcctttggat acttgtgttg ccatgacaga aggtagcatc
     6301 ggtttttggt tagttaatgc cctcgataat gaattgcaag cccaaggtat tcaaaaagaa
     6361 gtggcagctg ttgtcactca agtgatcgtg gatgccaaag acccagcttt tgaaaaccca
     6421 acaaaaccaa ttggtccatt tcttaccgaa gaagatgcca aaaaacaaat ggcggagtct
     6481 ggtgcaagtt tcaaagaaga tgcaggtcgt ggctggcgta aggttgtgcc atcaccaaaa
     6541 ccagttggta ttaaagaagc caatgtcatc agaagtctcg ttgattctgg cgttgttgtg
     6601 gttagtgctg gtggtggcgg tgtgcccgtt gtggaagatg ctactagcaa gaccctgact
     6661 ggtgtggaag ctgttattga caaggacttt gctagtcaaa ccctttcaga attggtggac
     6721 gcagacctct ttatcgtttt gacaggagtt gataatgttt acgtcaactt caacaaacct
     6781 gaccaagcca aattggaaga agtgactgtc tctcaaatga aagaatacat cacacaagac
     6841 caatttgcac caggtagtat gttaccaaaa gtggaagctg ccattgcttt tgttgaaaac
     6901 aaaccaaatg ctaaagccat tatcacatcg ctcgaaaata ttgacaatgt actatcagca
     6961 aacgctggaa cacaaattat cgcagggtaa tcaagaggat ttttagttct gtttaaaaga
     7021 ctcatttaat ggtattttct gaagagtacg actgacataa agagttgata ctgtttttaa
     7081 aggaaaagag tgtgccataa taaaaaacaa taatagtatt agaaaaggct aattttattg
     7141 agaattagcc ttttctttta gctttgatag gtgtataata accatactat tttttatttt
     7201 tcaaaatatt agaataaaca aaagtggaca acgtataaag agaactgcta agtcgttgag
     7261 ctcattagtc ccaaaaagat taccaaaaaa gaaggaagaa ctatgaagaa aagttttatt
     7321 catcaacaag aggagatttc ctttgttaag aatacgttca ctcagtattt gattgctaag
     7381 ttagatgttg ttgaagtgca aggacccatt ttaagtcggg tcggggacgg tatgcaagat
     7441 aatttgtccg gtactgaaaa tccagtatct gtcaatgtct tgaaaattcc taatgcaacc
     7501 tttgaagttg tgcattcatt agcaaaatgg aaacgtcaca ccttagcccg ttttgggttt
     7561 aatgaaggtg aaggccttgt tgttaatatg aaggctctcc gacctgatga ggattcactt
     7621 gaccaaaccc attctgtcta tgttgaccaa tgggactggg aaaaagtcat ccctgatggc
     7681 aaacgtaatc tcgcttacct caaagaaacc gttgaaacca tttacaaggt cattcggtta
     7741 actgaattag ctgtagaagc tcgttatgat attgaggctg ttttacctaa gaaaataacc
     7801 ttcattcata ccgaagaatt ggtagctaaa taccctgatt tgacgcccaa agaacgtgaa
     7861 aatgccatta ctaaagaatt tggagcagtc tttttaattg gtattggcgg ggttttacct
     7921 gacggtaaac cacacgatgg ccgcgctcct gactatgatg actggacaac agaaactgaa
     7981 aatggctatc atgggcttaa tggtgatatt ttggtttgga atgaccaact tggttcagcc
     8041 tttgaattat cctcaatggg gatccgtgtg gatgaagagg ccctaaaacg tcaggtggaa
     8101 atgactggtg accaagaccg cttaggcttt gattggcaca aatctttgtt gaatggactt
     8161 ttccctctaa cgattggtgg aggaatcggt caatcacgta tggtcatgtt tttgttgcgt
     8221 aaacaacata ttggagaagt tcagacctcc gtttggcccc aagaagttcg tgatagctac
     8281 gataatattt tataagtaat cacatcattt tgctaagttt tccacttgta taagagactt
     8341 taaataaatg atcagaaata ttgaaaaaag aaatcatttt taaggtttag agctagaaat
     8401 ttgctataat aaatgttatg agagttgtat caggtgaatt tggtgggcgt cctttaaaga
     8461 cgctcgatgg aaagataaca cgccctactt cagacaaagt tagaggtgcg atttttaata
     8521 tgataggacc ttattttaat ggtggtcgtg ttttagattt gtttgcaggt tcaggtggat
     8581 tagccattga ggctgtttct cgtgggatgt ctgctgcagt tttggttgag aagaatcgta
     8641 aagcgcaagc tattattcaa gacaatatta taatgactaa agctgagaat cggtttacct
     8701 tgttaaaaat ggaagctgag cgagctattg attgcttgac tggtcgattt gacttagtct
     8761 ttttagaccc tccttatgcc aaagaaacaa ttgtggcaac tattgaagct ttagcagcta
     8821 aaaacttatt gagtgaacag gttatggttg tctgtgagac agataaaaca gtcttgttgc
     8881 caaaagagat tgcaacgtta ggtatttgga aagaaaaaat ttatggaatt agtaaggtaa
     8941 cagtttatgt taactaaaat aggactttat acagggtcat ttgatcctgt tacaaacggt
     9001 catctcgata ttgttaaacg ggcaagtggc ctatttgatc aaatatatgt tgggattttt
     9061 gataatccta ccaaaaaaag ctattttaaa ctagaagttc gtaaagcaat gcttactcaa
     9121 gctctggctg attttacaaa tgtaattgta gtaacttcgc acgaacgttt agctattgat
     9181 gtagctaaag aattacgagt aactcacttg attagaggct tgcgaaatgc aactgacttt
     9241 gagtatgaag aaaatttgga atattttaat caccttttag ctccaaatat tgaaaccgtc
     9301 tatttgatat caagaaataa atggcaggcc cttagctcta gtcgtgtgag agagctaatt
     9361 cattttcagt cttccttaga aggtttggtt cctcagtcgg ttattgctca agtggagaaa
     9421 atgaatgaaa agacttaaaa aaatcaaatg gtggttagtg ggtctgctag ctttaatctc
     9481 tttgttgcta gcgttatttt ttccgctacc ttattatatt gaaatgcctg gaggcgctta
     9541 cgatattcgg actgtcttac aagtcaatgg caaagaagac aaacgaaaag gagcttacca
     9601 gtttgttgca gtgggcatta gtcgtgccag cctcgctcag ctattatatg cttggctgac
     9661 accgtttact gaaattagta cagcagaaga tacaacaggc ggatacagcg atgctgattt
     9721 ccttcgaatt aatcaatttt acatggaaac atcacaaaat gcagctattt atcaagcttt
     9781 atccttagct ggaaaaccag ttacattaga ttataaaggc gtatatgttt tagacgtaaa
     9841 caacgaatct acttttaaag gaacgctaca cttagcagat actgtaacag gtgtaaatgg
     9901 taaacagttt actagttcag cagaacttat tgactatgtt tctcacctaa aactagggga
     9961 tgaagttacg gttcagttta cgagtgataa taagcctaaa aaaggagttg gccgtattat
    10021 caaactgaaa aatgggaaaa atgggattgg cattgccttg actgatcata caagtgtcaa
    10081 ttcagaagac acagtgatct ttagtactaa aggagtagga ggacctagtg ctggtctaat
    10141 gtttactctt gatatatatg atcaaataac taaagaagat ttacgcaagg gccgtacaat
    10201 tgcaggtaca ggaactattg gcaaggatgg cgaagtagga gatattggtg gtgcaggtct
    10261 taaagtagtt gcagcagctg aagctggtgc agatatattt tttgttccga ataatcctgt
    10321 tgataaggaa attaaaaaag ttaatccaaa tgctataagt aattacgaag aagccaaacg
    10381 ggcagccaaa cgactaaaga ccaaaatgaa gattgttcct gttacgactg ttcaagaggc
    10441 actggtttat cttcgcaaat aaaataacta tgaatgtatt atattcaatt atattcacgc
    10501 tattaactca taaaaaacgg ttgaaccaga tagacagatc cttgaccagt cttttgggtt
    10561 caatcatttt ttacataaaa catatctaac ttgacagcgt aaaaaagatg ttataaaagt
    10621 ctagtggtaa aaaggcaata gagaattgag taaactttag tcgattatct ggaaatagag
    10681 catactaaaa acacctagtg aaaattgatt tttttcacta gctcatccaa gaacttgcgc
    10741 agataatcat gagtccattc catgactcta ttattctgga aagccttgca atagacaagt
    10801 taacgttata acaactaaat taaaaacttg agattgaaaa atccccataa acttatttta
    10861 caaggaggta aggctatggt aaccattaaa caagttgctg aagaagcagg tgtttctaga
    10921 tcaacagtct ccaggtatat ttctcaaaaa ggatatgtat ctgatgatgc aaggcataaa
    10981 atcaaagcag cgatagcaaa attacattac actccaaatg tcttggcgca gtcattgaag
    11041 acgaaaaaaa tcaactagtc ggtttattat taccagacat ttccaatcct ttttttccga
    11101 ggttagcaag aggagcagaa gaatatttaa aagaaaaggg gtatcgggtt atgctaggaa
    11161 atatttcaga cagcgaagct cttgaagaag aatacgtcca tgtccttctt caaagcaatg
    11221 ctgctggcat tattactacc catgacttta caaagcggta tcctactctt gctattccag
    11281 ttgtagtggt agatcgtgtt gaccaagaga cccagtacgg tgtcttttca gataataggg
    11341 cagggggctt attggcggct cagactgtct ggcaagcagg ggcaaaagaa gttttgttaa
    11401 taagaggtcc gctggataat gctgaaaaca ttaatgagcg gtttgaagct agtttttctt
    11461 accttcaaaa acaagacgtg actatgtatg tgtgtgatag tcagaatttt gattttgaaa
    11521 gtattcagct agaagctagt tacaacctca agtgttaccc aacaatagac agtattatag
    11581 caccttctga tatccatgct attgcttata ttcatgaact gcattctcaa ggtaaaaaga
    11641 ttcctcaaga tgttcaaata ataggttatg atgacatttt aatgagtcaa tttatttatc
    11701 cttctttatc gactattcat caatcctctt atttgatggg ccgttatgcc gccgaattag
    11761 tttatactat tgctagtcaa ttaactgtga aagcaaatcg gattaaattg cctgttcact
    11821 acgttgagcg agaaacaata aggaaaagat aagtaataat attagtccag attttagcag
    11881 gtatgatgaa gatttattgg gatttacctt ctactttaaa agaagttatc tgtcattact
    11941 ttcatcgcta tcagtcaaaa tgcattctta tgcaactctt aaccttaagc ttaatgtctt
    12001 tttgataaca tagaggaatg ttacacgatg atgatgcaat aaagcctaaa tatagtaatt
    12061 gtcgtgattt tatagctagt gagtaatgag atagcaagtc tctcatttac ttacaaaagt
    12121 caaaaaatag tgtataatgg ttgagttaca gataacactg caaaaaagat aacaagtgtc
    12181 cataattatc taagactata aaggcgatat agacagatat aaaaaagatg acgaatcagt
    12241 tatcactgga caattaaccg atttagttac aactaatgga tttttcagaa aggtgtcaaa
    12301 tgaaaaaaga aatttcgcca gaaatgtaca actataataa atttccaggt cccaaattta
    12361 ttcattttga agagcaagtt aaggctgaag gcattgattt gttactctta gaagatgtta
    12421 agaacgcttt tgatacgact agctttggtc aacgttatac agaagttctc ctaaagtatg
    12481 actatattgt tggcgattgg ggaaatgaac agcttcgtct taaagggttt tataaggata
    12541 gtgacgatat caagaaaacg aatcgcatct cacgtttaga agattatatt aaagaatttt
    12601 gcaattttgg ttgtgcttat tttgttttag aaaatcttca tccacaagat attaaatttg
    12661 aagaggagcg ccaaccaaga cgaaagaaat cacctaaatc aaaatcaaat cgtcgcaagc
    12721 caaactattc aaatcagcag cccgcaacac ctaagagcaa atcgaagcgg gcatcaaaag
    12781 aaaagcaacc tgaaaaccaa gcgtttacca gtcaaaaacg tcgaagtaat actaagcata
    12841 aagaaaagtc aaaacgtaat cagactagtc aacttaatac caaaattagt cattttatca
    12901 tcagaaagaa agataaataa tccatgaaac catcgattta tagcttaaca cgcgatgaac
    12961 tgatcgcgtg ggcagttgaa cgcggccaaa aacagtttag agctactcaa atttgggatt
    13021 ggctctataa aaaaagagtt caatcttttg aggagatgac gaatatttct aaagattttg
    13081 tttctatttt aaatgatagt ttctgtgtca atcctttaaa acagcgagtt gtacaagagt
    13141 cagctgatgg tacagtaaaa tatttatttg aactgcccga tggtatgtta attgaaacag
    13201 ttttaatgcg tcaacattat ggtcattctg tttgtgtgac gactcaagtt ggctgtaaca
    13261 ttggctgtac tttttgtgct agtggattga tcaaaaagca acgtgatcta aacagtgggg
    13321 aaattacagc tcaaatcatg ttagtccaaa aatattttga cgatagaaag caaggtgagc
    13381 gggttagcca tgttgtcgta atgggcattg gtgaaccttt tgataattac aaaaatgtca
    13441 tgtgctttct tcgcgtcatc aacgatgata atggcttagc aattggtgcc cgtcatatta
    13501 cagtctctac ctcagggtta gctcacaaga ttcgggattt tgcaaacgag ggagtacagg
    13561 ttaacttagc agtctcgttg catgcaccaa ataatgattt acgttcaagt attatgcgag
    13621 taaatcgctc ttttccgctt gaaaagctct tttcagctat agaatactat attgaaaaaa
    13681 cgaatcgtcg tgtcactttt gaatacatta tgctaaatga agttaacgat agcattaagc
    13741 aagctcaaga attagcagac ttaactaaaa ctattcgtaa gttatcttat gttaacttga
    13801 ttccgtataa tcctgtttca gaacatgatc agtatagtag aagtcctaaa gagcgagttc
    13861 tagcgtttta tgatgtgcta aagaaaaatg gagttaactg tgtggtgcgt caagagcacg
    13921 gaacagatat tgatgcagcc tgtggccagt tacgttctaa aacgatgaaa aaagatcgcg
    13981 aaaaggttac agcgacaaaa taaagcccaa aaaatatctt tgattgacaa tgcttgatga
    14041 caaaatattc ctagtcacta aaatgactag gttttttatc tggcctaaaa atgctctaga
    14101 agcacaatcc aaaataatcc aaaactaaga taaggaataa aaggtatgcg cttgatgcct
    14161 aatagtaagc aagcagtaat acctgctaaa ctagcaagtt gaattagcca aatcaacgac
    14221 gttagatcca atactaaagc taagctagca aggtagaaaa aatcgcctgc tccaattgaa
    14281 aaaggtctta aatgagctaa taaacctagt agcagtaata tcaatgataa ataattgatc
    14341 gaataaaaca ggagtagact tacaaagcta aaaagccaca agataaaagg gtattcttga
    14401 gaacgccaat caaataaact aaataataaa gaaaagagta acaagtaaca gtaactagca
    14461 ctaacccaat gtaccatact agcccataag ataattatta gacctatctc taagctaaag
    14521 aagatttttt ggctagttat aaaatggttt tggaactgcc gaaaaacgcg tttggcaaaa
    14581 gttagttggt cacaaacaat gacagtctgt ttacttagct gctcttgacc attatcagga
    14641 aaataaagta gtaaacagta aaaaagatgg gtcaataaga tgcccgaaca tatactaaaa
    14701 aaagctatca tacttattta ttcgaaaaga aatcaaatac ttgcaatctt tccttaatca
    14761 ttgtagaata tagatataaa acgataatga ttctaattaa gtgtctaatc atccaattag
    14821 gattattccg ttattgtcga ataggattag gtccttaacc ctttcttatg tttatcacgt
    14881 tagggttagt tccctctcca ttcttgccct ttaagctgaa aagtaaggag atgttattat
    14941 gacaaacaca ctcgttgaaa atatttatgc ttcagtaact cacaatattt ctaaaaaaga
    15001 agcatcaaaa aatgaaaaaa ctaaagctgt tttaaaccaa gctgtcgctg acttatctgt
    15061 ggctgcatct attgtgcacc aagtacactg gtatatgcgt ggtccaggtt tcttgtacct
    15121 tcaccccaaa atggatgaat tacttgatag cttgaatgct aatttagatg aaatgagcga
    15181 gcgtttgatc actattggcg gagcgcctta ttctacccta gctgagtttt ctaaacactc
    15241 taaattggac gaagcaaaag gtacttacga taaaaccgtt gctcagcatt tagcaagatt
    15301 ggtcgaagtt tacctttacc tcagcagcct ttaccaagtt ggtttggata ttaccgatga
    15361 agaaggcgat gctggaacaa acgatttgtt tacagcagct aagacagagg ctgaaaaaac
    15421 catttggatg ctccaagcag agcgtggaca aggcccagca ctctaattga ttatgcctta
    15481 ggataaaaga agtcaatgat aaaattggct tcttttttat ggaatcatcg attcattttc
    15541 agaaacatag aaagcgattc catacttgtc ttgaaatctg ccgtagaatt tgctaaaatc
    15601 tacttatatg aaaacactat atgatgtgca acaattgcta aaaaactttg gcatttttgt
    15661 ttaccttggc aaacgtcttt atgatattga aatgatgaag attgaacttc agcgtctcta
    15721 tgatagcggc ttattggata agagggatta cttaaatgcg gagttaattt tgcgacgtga
    15781 gcatagatta gaattggaaa aagaaggata gacaaatgag tcaaaaatta ctggggattg
    15841 atttaggtgg taccaccatt aaatttggaa ttttaacagc agcaggagaa gtccaagaaa
    15901 aatgggcaat tgagactaat attttagaag gaggcaaaca tattgtccct gatatcatcg
    15961 cttccatcaa acatcgctta gacttgtatg gtctaagcag tgctgacttt gtgggaattg
    16021 gtatgggatc accaggagcg gttgaccgtg atactaatac agttactggg gcattcaacc
    16081 ttaattggaa agaaacccaa gaagtcggtt ccgttgttga aaaagaattg ggcattcctt
    16141 ttgccattga caatgatgcc aatgtggctg cccttggtga acgttgggta ggtgctggtg
    16201 aaaataaccc agatgtcgtc ttcatgacac ttggaacagg tgtcggtgga ggcattattg
    16261 ctgatggtaa cttgattcat ggtgttgcag gagcaggtgg tgaaatcggc cacatgattg
    16321 ttgagccaga aaatggcttt gcttgtactt gtggctcaca cggctgtttg gaaacagtag
    16381 cttcagcaac aggagttgtc aaagtggcac gtttactggc agaagcctac gaaggggatt
    16441 cagccatcaa agcagctatt gacaatggtg aaggtgttac cagtaaagac attttcatgg
    16501 cggctgaagc aggggattcc tttgctgatt ctgttgtgga aaaggttggt tactaccttg
    16561 gccttgcttc agcaaatatt tccaatatct tgaatccaga ctcagtggtt atcggtgggg
    16621 gtgtgtcagc agcaggagaa tttctacgct cacgtattga aaaatacttt gtgaccttca
    16681 ctttcccaca agtgaggtat tcaactaaaa ttaagattgc agaacttggc aatgatgctg
    16741 gaattatcgg tgcagctagc cttgctcgac aatttatcac aaaataggag ggggatatgt
    16801 ctccaatcac acttatctta tggttacttc ttgtcggcat tgttggttat tatacatgga
    16861 actatttctc ttttcgaaaa atggcaaagc aggttgataa cgagactttt aaagacgtga
    16921 tgcgtcaagg tcaattgatt gatttacgag agccagcggc ttttagaact aagcatattt
    16981 taggagctcg aaattttcca gcgcaacaat ttgatgctgc tattaaggga ctacgcaagg
    17041 acaaacctgt tcttatttac gaaaatatgc gtccccagta ccgtgtgcct gcggtcaaaa
    17101 aacttaaaaa agctggcttt gaagacgttt atgtcttaaa agacggtatt gattattggg
    17161 atggcaaagt taaacaaaca acctagttaa gagtaacgtg gagttaaggg gaataaaggc
    17221 agtcactgtc tcaaaaacct taattccttt ttttgctgta tccagacttg ctgaaagtct
    17281 gaaaacattt acaattgatt aaaaccagtt ttttaaaaca ttttgtgtta tacttatcta
    17341 gttaaaatat atttacttag aggaacaaat gactaactta agaaacgata tccgtaacgt
    17401 agcgattatt gcccacgttg accacggaaa aacaacactt gtagatgaat tattaaaaca
    17461 atcccatact cttgatgagc gtaaagagct tcaagagcgt gccatggatt ccaatgacct
    17521 tgaaaaagaa cgtgggatta caatccttgc gaaaaatacg gcagtagcct ataacgatgt
    17581 tcgtattaac atcatggata ccccaggaca cgcggacttc ggtggtgaag ttgaacgtat
    17641 catgaaaatg gttgacgggg ttgttcttgt tgtggatgcc tacgaaggaa caatgcccca
    17701 gacgcgtttc gtattgaaaa aagcacttga gcaaaacctt atcccgatcg ttgtggtgaa
    17761 caagattgac aaaccttcag ctcgtccagc agaagttgta gatgaagtgc ttgaattatt
    17821 catcgaactt ggtgccgatg atgagcaatt ggaattccca gttgtttacg catcagctat
    17881 taatggaaca tcatcattat cagatgaccc tgctgaccaa gagcatacta tggcaccgat
    17941 ctttgatacg attattgatc atattccagc gccagttgat aattcagatg agcctttgca
    18001 attccaagtg tcacttttgg actacaacga tttcgtaggt cgtatcggta tcggtcgtgt
    18061 tttccgtggt actgttaaag tgggtgacca agtaactctt tcaaaacttg atggtaccac
    18121 taaaaacttc cgtgttacaa aactgtttgg tttcttcggt ttggaacgtc gtgaaattca
    18181 agaagctaaa gcaggtgact tgattgctgt ttcaggtatg gaagatatct ttgttggaga
    18241 aaccattaca ccaactgact gtgtggaagc tctgccaatt cttcgtattg atgagccaac
    18301 acttcagatg actttcttgg tcaataactc tccttttgca ggtcgtgaag gtaaatggat
    18361 cacgtcacgt aaggttgaag aacgtctttt agcagaattg caaacagacg tgtcacttcg
    18421 tgttgaccca acagattcgc cagataaatg gacggtttca gggcgtggag aattgcattt
    18481 atctatcctc attgaaacca tgcgccgtga aggctatgaa cttcaagtat cacgtccaga
    18541 agttatcatc aaagaaattg atggtgtcaa atgtgaaccg tttgagcgtg ttcaaattga
    18601 tacaccagaa gaatatcagg gtgcaatcat ccagtctctt tcagaacgta aaggggatat
    18661 gcttgatatg cagatggttg gtaatggtca aacgcgtttg attttcttga ttcctgcacg
    18721 tggtttgatt ggttattcaa cagagtttct ttcaatgaca cgtggatatg gtatcatgaa
    18781 tcatactttt gatcagtatc taccggttgt tcaaggagaa atcggtggcc gtcatcgtgg
    18841 tgccttggtt tctattgaaa atgggaaagc aacgacatat tcaatcatgc gtattgaaga
    18901 acgtggaact atctttgtca atccaggtac agaagtttac gaagggatga ttgttggtga
    18961 aaactcacgt gataacgacc ttggtgttaa cattacaaca gctaagcaaa tgacaaatgt
    19021 ccgttcagtg actaaagatc aaactgcagt tatcaagacg cctcgtatcc taacgcttga
    19081 agaatcatta gagttcttga atgacgacga atacatggaa gtaacgccag aatctatccg
    19141 cttgcgtaaa caaatcttga ataaagctgc gcgtgataaa gctaataaaa agaaaaaatc
    19201 agccgaatag cttttgaagt taaactaact aaataaaata gcaaaaagat atttaagaaa
    19261 agtcattttt taaaggtctt tttgcgttta caagttccta tggaatataa accaaaataa
    19321 aggaggacgg aatgttttac cttattatgg ctgtctcgat tatatcttat tatctataca
    19381 tggctcctaa aagtgtccgt aacacccttg ggatgattgg tttagttggc ttggttgctc
    19441 tgcttattgt tttagcgggc ttgagtttta tcaaaatcat gcaaacccct cctgaatttt
    19501 ttattgggat gggaatggtg gcattgggct attttgcttt aaaagatgtg cgtaaaatga
    19561 ccaaaaaacc gagagttaaa taaaaatact taaataaaaa tacttaaaga ttgatgattt
    19621 tggtttttat acgataaaag gactgatttg ttttagacaa tatcagtcct tttttaatag
    19681 ttcatttttt ctgaaagaaa gcttttagcc gattttcatt gagtgtgcaa ctaaaaagag
    19741 atgcttggta gtgacagtta agacctctga ctagtatttt atcttatttt acttaaaaaa
    19801 acgtatcaat aatctcacaa atatgggcat gatgtttgta tattggaaac ggattctaat
    19861 tctaaactca agaacggtat ttttaaaatg ttgaaaaagc atctaaataa aggtaaaata
    19921 gaaatcaaat agaatggata gtgtgagctt agatgaaagt gataagtaat tttcaaaaca
    19981 aaaaaatatt aatattgggg ttagccaaat cgggcgaagc agcagcaaaa ttattgacca
    20041 aacttggtgc tttagtgact gttaatgata gtaaaccatt tgaccaaaat ccagcggcac
    20101 aagccttgtt ggaagagggg attaaggtca tttgtggtag ccacccagta gaattattag
    20161 atgagaactt tgagtacatg gttaaaaacc ctgggattcc ttatgataat cctatggtta
    20221 aacgcgccct tgcaaaggaa attcccatct tgactgaagt agaattggct tatttcgtat
    20281 ctgaagcgcc tattatcggg attacaggat caaacgggaa gacaaccaca acgacaatga
    20341 ttgccgatgt tttgaatgct ggcgggcaat ctgcactctt atctggaaac attggttatc
    20401 ctgcttcaaa agttgttcaa aaagcaattg ctggtgatac tttggtgatg gaattgtcct
    20461 cttttcaatt agtgggagtg aatgcttttc gccctcatat tgctgtcatc actaatttaa
    20521 tgccgactca cctggactat catggcagtt ttgaggatta tgttgctgct aaatggatga
    20581 ttcaagctca gatgacagaa tcagactacc ttattttaaa tgctaatcaa gagatttcag
    20641 caactctagc taagaccacc aaagcaacag tgattccttt ttcaactcaa aaagtggttg
    20701 atggagctta tctgaaggat ggaatactct attttaaaga acaggcgatt atagctgcaa
    20761 ctgacttagg tgtcccaggt agccacaaca ttgaaaatgc cctagcaact attgcagttg
    20821 ccaagttatc tggtattgct gatgatatta ttgcccagtg cctttcacat tttggaggcg
    20881 ttaaacatcg tttgcaacgg gttggtcaaa tcaaagatat taccttctac aatgacagta
    20941 agtcaaccaa tattttagcc actcaaaaag ctttatcagg ttttgataac agtcgcttga
    21001 ttttgattgc tggcggtcta gatcgtggca atgaatttga cgatttggtg ccagaccttt
    21061 taggacttaa gcagatgatt attttgggag aatccgcaga gcgtatgaag cgagctgcta
    21121 acaaagcaga ggtctcttat cttgaagcta gaaatgtggc agaagcaaca gagcttgctt
    21181 ttaagctggc ccaaacaggc gatactatct tgcttagccc agccaatgct agctgggata
    21241 tgtatcctaa ttttgaggtt cgtggggatg aatttttggc aacctttgat tgtttaagag
    21301 gagatgccta atgcctaaga agattttatt tacaggtggt ggaactgtag gtcatgtcac
    21361 cttgaacctc attctcatac caaaatttat caaggacggt tgggaagtac attatattgg
    21421 tgataaaaat ggcattgaac atacagaaat tgaaaagtca ggccttgacg tgacctttca
    21481 tgctatcgcg acaggcaagc ttagacgcta tttttcatgg caaaatctag ctgatgtttt
    21541 taaggttgca cttggcctcc tacagtctct ctttattgtt gccaagcttc gccctcaagc
    21601 ccttttttcc aaaggtggtt ttgtctcagt accgccagtt gtggctgcta aattgcttgg
    21661 taaaccagtc tttattcatg aatcagatcg gtcaatggga ctagcaaaca agattgccta
    21721 caaatttgca actaccatgt ataccacttt tgagcaggaa gaccagttgt ctaaagttaa
    21781 acaccttgga gcggtgacaa aggttttcaa agatgccaac caaatgcctg aatcaactca
    21841 gttagaggcg gtgaaagagt attttagtag agacctaaaa accctcttgt ttattggtgg
    21901 ttcggcaggg gcgcatgtgt ttaatcagtt tattagtgat catccagaat tgaagcaacg
    21961 ttataatatc atcaatatta caggagaccc tcaccttaat gaattgagtt ctcatctgta
    22021 tcgagtagat tatgttaccg atctctacca acctttgatg gcgatggctg accttgtagt
    22081 gacaagaggg ggctctaata cactttttga gctactggca atggctaagc tacacctcat
    22141 cgttcctctt ggtaaagaag ctagccgtgg cgatcagtta gaaaatgcca cttattttga
    22201 gaagaggggc tacgctaaac aattacagga acctgattta actttgcata attttgatca
    22261 ggcaatggct gatttgtttg aacatcaggc tgattatgag gctactatgt tggcaactaa
    22321 ggagattcag tcaccggact tcttttatga ccttttgaga gctgatatta gctccgcgat
    22381 taaggagaag taaatggcaa aagataaaga gaaacaaagt gatgacaagc tcgttttgac
    22441 agagtggcaa aagcgtaaca ttgaattttt aaagaaaaag aagcagcaag ctgaggaaga
    22501 aaaaaaactc aaagagaaat tattgagtga taaaaaagcg cagcagcaag ctcaaaatgc
    22561 ttctgaagcg gttgagctta aaactgatga gaaaactgat agtcaggaaa ttgagtcaga
    22621 aacgacgtca aaacctaaaa aaaccaaaaa agttagacaa cccaaggaaa aaagcgcgac
    22681 acaaatcgct tttcaaaaat ccttgcctgt tcttttgggg gcgctcttac tcatggcggt
    22741 gtctattttt atgatcactc cttatagcaa aaagaaagag ttttctgtaa gaggaaacca
    22801 tcaaacgaac cttgacgaat taatcaaagc tagcaaagtc aaagcatctg actattggtt
    22861 aacgctgtta acttcgcctg gtcagtatga acgaccgatt cttcgtacta ttccatgggt
    22921 gaaatctgta catctctctt accaatttcc taatcacttt ctatttaacg ttattgaatt
    22981 tgaaatcatc gcttatgcac aagttgaaaa cggttttcag cctattttgg agaatggaaa
    23041 acgtgtggac aaggtcaggg catcagaact accgaaatct ttcttgattc ttaatttaaa
    23101 agatgagaaa gcgatccaac agttagttaa gcaattaacg acattaccta aaaaattagt
    23161 caagaatatc aagtcagtgt ctcttgcaaa ttccaaaacg acagcggatt tactacttat
    23221 tgaaatgcat gacggtaatg tagttagagt accgcagtca caactcacat tgaaacttcc
    23281 ctattatcaa aaattgaaaa aaaaccttga aaatgatagt atagtggata tggaagtggg
    23341 aatttatact acaacacagg agattgaaaa tcaacctgaa gttcctctta cgcctgaaca
    23401 aaacgcagct gataaagaag gagataagcc tggtgaacat caggaacaga cagacaatga
    23461 ttcagaaacg ccagcaaatc agagtagtcc tcagcaaaca ccaccatccc cagaaacggt
    23521 cctcgaacag gcccatggct agctaatatc taagttgaaa aagcaatgaa aacgttagaa
    23581 attcaacgat tctaacccat aatgaattgc ctaaaaaaaa ttaagtttat ataacaaaaa
    23641 acgtaaaatg ataacatttt acgttttttt atggtataat attttctgaa tgattctgtt
    23701 ttttagcagt ttttagaata gcaaaagttt ggaaagtaag tgaggtcaag tgaatggcta
    23761 gaaatggctt ttttactggt ttggacattg gaacaagctc gataaaagtt ttagtagcag
    23821 aatttatttc tggtgagatg aacgtcattg gtgttagtaa tgttccaagt accggcgtaa
    23881 aagatggcat aataatcgat atagaggcag ctgcgactgc catcaaaact gcggtagaac
    23941 aagcagaaga aaaagcaggg atgacaattg aaaaggttaa tgttgggcta ccggcaaacc
    24001 ttcttcaaat tgaaccaaca caaggaatga ttcctgtccc aagtgagtct aaagagataa
    24061 aagatgagga tgttgatagc gttgttaaat cggctttaac aaaaagtatc acaccagaac
    24121 gagaggttat ctctttagtt ccagaagagt tcattgtgga tggctttcag ggcattcgag
    24181 atccacgtgg tatgatgggg attagattag agatgcgcgg gcttatttat actggaccaa
    24241 gcaccatttt acataatctg cgtaaaacgg tagaaagagc aggcattaaa gttgaaaaca
    24301 tcattatttc tccgttagct atggctaaaa ccattttaaa cgaaggtgag cgcgagtttg
    24361 gagctactgt aattgatatg ggaggtggac agacaactgt cgcttctatg cgagcacaag
    24421 aattgcagta taccaatata tatgccgaag gcggcgaata cattactaaa gatatatcaa
    24481 aagtattaaa aacgtctttg gctattgcag aagcacttaa gtttaatttt ggtcaagcgg
    24541 agatatcaga agctagtata actgaaacag taaaagttga tgtggtaggt agtgaagagc
    24601 ctgttgaggt aactgaacgt tatttatctg aaattatttc agcgcgtatt cgtcatattt
    24661 tagatcgtgt gaagcaagat ttggaaagag gtcgtttact agacttacca ggaggcattg
    24721 ttttgattgg tggcggtgca atcatgcctg gagtggtaga aattgcacaa gaaatctttg
    24781 gagtaactgt aaagctccat gttccaaacc aagtcggtat tagaaatcca atgttttcaa
    24841 acgttatcag tttggtagaa tatgttggta tgatgtctga agtagacgtt ttagcacaaa
    24901 ctgcagtttc aggagaagaa cttttgcgac gcaagcctat cgatttcagt ggccaagaat
    24961 cttatttacc agattatgat gattcaagaa gaccagaatc gaccattggc tatgaacaac
    25021 aagcgtcaca aacagcatat gattcacaag ttccgagtga tcctaaacaa aaaatttcag
    25081 aacgtgttcg tggcatattt gggagtatgt ttgattaaaa gtaataaagt gaggaaataa
    25141 aatggcattt tcatttgata ctgcatcaat tcaaggtgca attataaaag taattggagt
    25201 cggcggaggt ggcggaaatg ccattaatcg tatgattgat gaaggtgttg ctggtgtcga
    25261 gttcatcgca gcaaacacag acattcaggc attaagctca tcaaaagctg aaacggttat
    25321 tcaactaggc cctaaattaa ctcgtggact tggtgctgga ggacaacctg aagtaggacg
    25381 taaagctgct gaagaaagcg aagaaatttt aacagaagct cttacaggag cggacatggt
    25441 atttattact gccggtatgg gtggtggctc tgggacaggg gctgcaccgg ttattgctcg
    25501 tatcgctaaa agtttgggag ccttgacagt agctgttgtt actcgcccgt ttggttttga
    25561 aggtaacaaa cgtggtaatt ttgctattga aggtatcgaa gaactacgtg aacaagttga
    25621 tactttgtta attatttcaa ataataacct tcttgagatt gttgataaaa agacaccttt
    25681 attagaagca cttagtgaag ctgataatgt tttacgccag ggagttcaag ggataaccga
    25741 cttaattact agtcctggcc ttatcaatct cgattttgcc gacgtgaaaa cagttatggc
    25801 aaataaaggg aatgccttga tggggattgg gattggctct ggagaagagc gcattgttga
    25861 ggcggcgcgt aaggcaatct attcacccct attagaaacg actattgatg gtgcacaaga
    25921 cgttattgtg aacgttacag gaggtctcga catgacactt acagaagctg aagaagcctc
    25981 tgaaattgtt gggcaagctg ctggtcaagg cgttaacatt tggttaggaa catctattga
    26041 tgatactatg aaagatgaca tccgtgtgac tgttgtagca actggagtgc gccaagaaaa
    26101 agccgaacaa gtttcaggtt ttcgtcagcc taggactttt acccaaacca acgcgcagca
    26161 agtagcgggt gcacaatatg catcagatca agcaaaacag tcggttcaac cagggtttga
    26221 tcgtcgctca aattttgatt ttgacatggg ggagtctcgc gagataccaa gtgcacaaaa
    26281 ggtaatttct aatcataatc aaaatcaagg ttctgctttt ggaaattggg atttgagacg
    26341 tgataatatt tctcgtccaa cagaaggtga attggataac catcttaata tgtcaacgtt
    26401 ctcagctaac gatgacagtg atgatgaatt agaaacgcct ccattcttta aaaaccgtta
    26461 ataatggatt tactgacaaa taaaaagaaa atttttgaga ctatccgctt atctacagag
    26521 gcagcaaata ggactaatga tagtgtttca gttattgctg taacaaaata tgtggatagt
    26581 acaattgcag gtcagcttat cgaagcagga attgagcaca ttgccgaaaa ccgtgttgat
    26641 aaatttcttg aaaagtatga tgcgttaaag tatatgccag taaagtggca tttaattggt
    26701 accttacaac gtcgtaaagt caaggaagtt atcaattatg ttgattattt tcacgctcta
    26761 gattctgtga gattagcttt ggaaatcaac aagagagctg accatcctgt gaagtgtttt
    26821 ctacaagtta atatttctaa agaagagagt aaacatggtt ttaacatttc tgagattgat
    26881 gaagcgattg gagaaatagg taagatggag aagatacagt tagttggttt aatgactatg
    26941 gcaccagcaa atgccagtaa agaaagtatt ataactattt ttcgacaagc aaatcaatta
    27001 agaaaaaact tgcagttaaa aaaaagaaag aatatgcctt ttacagaatt gagcatgggc
    27061 atgagtaacg attatccaat tgctattcaa gaaggctcaa cttttattcg gattggtaga
    27121 gctttctttc actaatggag aataagatgg cttttaaaga tacatttaac aagatgattt
    27181 cttattttga cacggatgag gttaacgaag ttgaagaaga tgttgcagca tcaactgata
    27241 acgttattcc aagatcacaa caatcagtca gagcaagtag tcatccaaaa caagaaccta
    27301 gaaacaatca cgtacaacaa gatcatcaag cgagatccca agaacagaca aggtcacaaa
    27361 tgcatccaaa acatggcact tctgaacgct attatcagca gtctcagcca aaagaaggcc
    27421 atgaaatggt tgacagaaga aaacggatga gcacttctag tattgcaaat cgccgtgagc
    27481 agtatcaaca atcaacttgt tcagatcaaa caactattgc cttaaagtat cctcgtaaat
    27541 atgaggatgc tcaagaaatt gtggatcttt taatagttaa tgaatgcgtt ttgattgatt
    27601 ttcagtttat gctagatgct caggctagac ggtgtttaga ttttattgat ggtgctagta
    27661 aagtgctcta tggtagctta caaaaggtcg gctcttcaat gtacttactg gctccgtcaa
    27721 atgtatccgt caatatagaa gaaatgacta tcccacatac tacacaagat attggctttg
    27781 attttgatat gaaaaggcgg taaataaatg atattaatac tatctattct tcttcgtctg
    27841 atcaaagttt acacttattt attgattgct tacgcattaa tgtcatggtt tcctggggca
    27901 tatgattcaa aaattgggcg tttgattagt ggtatcgttg aaccaatttt aaaacctttt
    27961 agagcattta atttacaatt tgccggtctt gacttcacta tttttgtcgt cattattagt
    28021 ttgaattttt tagctcaagt tttggtccgt gtgtttattt aatggttagt catagtaaga
    28081 tttatcagca ttttcaccaa gaagaatatc cttttattga tagaatgtct gatatgatta
    28141 atagagttga agattactat cttttagaag ttactgagtt tttaaatcct agagaagtga
    28201 tgattttaaa aagtttgatt gctttaacag atctaaaaat gttcgtatca acagattact
    28261 acccaagcga atatggtcgt gtcattattg cacctggtta ctatgactta gaacaaagtg
    28321 attttcaaat agctttagta gagataagtt atcaggcaaa gtttaatcag ttgacacata
    28381 gtcaaatttt aggaacttta attaatgaat taggagtaaa gcgaaattta tttggagatg
    28441 tttttgttga aatgggatat gcccagctca tgattaagcg ggagttattg gattattttt
    28501 taggaacaat tactaaaata gctaaaacta gtgtgaaatt aagagaagtt aactttgatc
    28561 agttaattag gtctattgat aacagccaga ccctggatat tctagtttct agttttcgat
    28621 tagatggtgt agttgctact atcttaaaaa aatctcgaac gcaagttata gcattaattg
    28681 aagcaaataa gattaaggta aactatcgag ttgctaataa agcttcagat aatctagtca
    28741 taggggatat ggtgagtatc agaggtcacg ggcgttttac tcttttagca gataatggag
    28801 tgaccaaaca tggcaaacaa aaaataacac taagtaaaat gatacataaa taaggagata
    28861 caatggcact tacaacgcta gaaattaaag ataaaacttt taagacaaaa ttccgaggat
    28921 actgtgaaga agaagtcaat gaattccttg atattgttgt tgatgattac gaagctcttg
    28981 tacgtaaaaa tcgtgataac gaagcaagaa ttaaagatct tgaagaaaaa ttatcttact
    29041 ttgatgaaat gaaagagtca cttagccagt ctgtaatctt agctcaagaa acagctgaaa
    29101 aagtgaaagc aacggctaat gcggaagcaa caaacttggt tagtaaagcg acttatgatg
    29161 ctcagcattt attagatgaa tctaaagcta aagccaatca aatgttgcgt gatgcaactg
    29221 atgaggctaa gcgagttgcg attgaaacag aagaactaaa gcgtcaaaca cgtgtgttcc
    29281 accaacgttt aatctcatct attgagtcac aattaagctt atcaaattca cctgaatggg
    29341 atgaactgct acaaccgact gcaatctatc ttcaaaattc tgacgatgct tttaaggaag
    29401 tcgtgaagac cgttcttaat gaagacattc ctgaatctga tgatagtgcc tcttttgatg
    29461 caacacgtca gtttactcca gaagagttag aagaattgca acgtcgtgtt gatgaaagca
    29521 ataaggagtt agaggcttac caacttgact ctcaatctga ttctacgact gagccagagg
    29581 taaatctcag tgaaacacaa acgtttaaat taaatatcta aataaagaaa aacaagatga
    29641 tttgcttata atcacagcaa gcgggagatg atgagagtct cgtattccct aagtattatc
    29701 attatcattt tctaaaattt tcgctgaact acagtaagcg aggaggtttg ttcaccttac
    29761 gagcaaagag ggagcggtaa gtcttatgat atattatcgc tctgaactaa ggtggtacca
    29821 cgagctttcg tcctttttga gacgaggctt ttttcgttat agtcgcaagt ttgtttaaaa
    29881 ggagtttgaa ataatgaaat taaaagagac acttaatcta ggaaaaacag cctttccaat
    29941 gcgcgcaggt cttcctaata aagagccaca atggcaagca gcttgggaac aagcagagct
    30001 ttacaaaaaa cgtcaagaat tgaatgcagg taagcctgcc tttcatcttc atgatggacc
    30061 tccatacgct aacggcaata ttcacgttgg gcatgccctt aataaaattt caaaagatat
    30121 cattgtgcgt tctaagtcca tgtctggctt tcaagcgcct tatgtacctg gttgggacac
    30181 acacggcctt ccaatcgaac aagtcttggc taagcaagga atcaaacgta aggagatgga
    30241 tttagcagaa taccttgaga tgtgtcgtca atacgcttta agtcaggttg ataaacagcg
    30301 agatgatttc aaacggttag gtgtttcggc agactgggaa aatccttatg tcactttgga
    30361 cccacagttt gaagctgatc aaattcgtgt ttttggagcg atggctgaaa aaggttacat
    30421 ctatcgtggt gctaaacctg tttattggtc atggtcttca gaatcggcct tggcagaggc
    30481 tgaaattgaa taccatgaca tcgattcaac ctctttatac tacgccaata aagttaaaga
    30541 tggtaaaggt atccttgata ctaatacgta tatcgttgtt tggaccacaa caccatttac
    30601 cgttacagca tcacgcggtt tgactgttgg tcctgatatg gattatcttg tggtgaaacc
    30661 tgctggttca gaccgtcaat atgttgtggc agaaggtctt ttggatagcc ttgctggaaa
    30721 atttggctgg gaatcttttg aaactttagc tagccataaa ggagctgatt tagagtacat
    30781 tgtgacagaa cacccatggg atactgacgt agaagaattg gttatccttg gtgaccatgt
    30841 tacccttgag tcagggacag ggattgtcca cacagcacca ggttttggtg aggatgacta
    30901 caatgttggg acaaaataca aactggaagt tgctgtgact gttgatgaac gtggcctaat
    30961 gatggaaaat gcaggtccag atttccacgg acaattttat aacaaggtaa cgccgattgt
    31021 cattgataaa cttggtgatc ttttattggc acaagaagtg atcaatcact cttacccatt
    31081 tgactggcgg acgaaaaaac caatcatctg gcgtgctgta ccgcaatggt ttgcttctgt
    31141 ttctgatttc cgtcaagata ttttggatga aattgaaaaa acaacctttc atccatcatg
    31201 gggtgaaaca cgcctttaca atatgattcg tgatcgtggc gactgggtta tttctcgtca
    31261 acgtgcttgg ggagttccgc ttcctatctt ctatgccgaa gatggcacag ctattatgac
    31321 taaagaagtg acagatcatg tggctgattt gttccaagaa aatggatcaa tcatttggtg
    31381 gcaaaaagaa gctaaagacc tattaccaga gggcttcact catccagggt caccaaatgg
    31441 cgagtttaca aaagaaactg atatcatgga cgtttggttt gactctggtt cttcttggaa
    31501 tggagtcatg aatactaaag aaaatctttc ctatccagcg gatctatact tagaaggctc
    31561 tgaccagtat cgtggttggt tcaattcatc cttaattaca tctgtggctg ttaatgggca
    31621 tgctccatat aaggctattt tatcgcaagg ctttgttctt gatggtaagg gcgaaaaaat
    31681 gtctaaatca aaaggcaata tcatttctcc taatgatgtg gctaaacaat atggtgcaga
    31741 tattcttcga ctttgggtag cttctgtgga taccgataat gatgtccgtg tttctatgga
    31801 gatccttggt caagtctctg aaacttaccg taaaatccgt aacacccttc gcttcttgat
    31861 tgctaataca tctgatttca accctgctac ggatacagta gcttatgcag atttaggaac
    31921 tgttgataag tacatgacaa ttgtctttaa tcagttggta gcaacgatta ctgacgctta
    31981 tgagcgttat gactttatgg ctatttacaa agcagtggtg aactttgtta cggttgattt
    32041 atcagccttc tatcttgatt ttgctaaaga cgttgtctat attgaagctg ccaatagctt
    32101 agaacgtcgt cgcatgcaga cagtcttcta tgatatcttg gttaagatta ccaagttatt
    32161 gacgccaatc ttgcctcaca ctactgaaga aatctggtct tatctagagt atgagtcaga
    32221 agcatttgtt caattggcag aaatgcctgt ggcagaaacc ttctcggctc aagaggatat
    32281 tttagaagct tggtcagctt tcatgacttt gcgtactcaa gctcaaaaag ctttggaaga
    32341 agcgcgaaat gctaagatta tcggtaaatc attggaagcc catttgacca tctacgctag
    32401 tgaagaagtg aaaaccttat tgactgcttt agacagcgat attgctttgc ttttgatcgt
    32461 gtctcaatta accattgctg acttggcaga tgcgcctgcg gatgcagtgg catttgaagg
    32521 tgttgccttt atagtagaac atgccatagg tgaagtttgt gagcgttcac gtcgcatcga
    32581 cccaactact cgcatgcgtt cttacaatgc atttgtctgt gatcacagcg ctaaaatcat
    32641 tgaagaaaat ttcccagaag ctgtggctga agggtttgaa gagagtggca aataagtctt
    32701 atcaagactt gaagtgacac tgagtaagaa gacaaccatc gggtcttagg acctgatggt
    32761 tttttagtag agctgattac gtccattagc cagctttaac gagagacaaa gtaggagaaa
    32821 tttagactac ttttttaatt tcttttaaga aaattgctgg cttcatataa ggactattaa
    32881 gatagagttc acctttcgct aataaaaaaa cttagctctt ttagaagggc taagttttgt
    32941 ctgaatagct ggctgctgtt tatacagaag tttgaaatga aatttcaata aggttattcg
    33001 tgtgaagtgt ttttgattgt ccaggaataa caattttagg atcaatttta cgttttaaaa
    33061 aaaattcgcg aatgatatca agttcatcct ccttgatggc acggtattta tttgaaataa
    33121 gtagttcgta atgttttggt gcttgggtaa aaatgacatc tgtatttcct gctgagtata
    33181 cttcgactaa ataggcatcg gtgtttttta gctgattttt gatgagttct gggtgactgc
    33241 tagtggtatt gatgagtctc ataaatgtcc tccttagtat tcctgtacct attatagcac
    33301 taatttaaag ccttagttag tagaatgatg ctttttttgc cattccttga ctccccattg
    33361 atggctctct cgttttaatt tagcaattgc ctcgatagga gaaaaccaac ctaagttatt
    33421 aaaatcttct aagggcttag aaacggcttg aaatgcagtt acttcataaa gataggcagg
    33481 atggtagaag tgggtatcac gatggcgaga gtagaaatat tcatctgcct gaccgtaata
    33541 tgaaccaata gtagcagaaa aaccaagttc ttcaatcagt tcacgctcta gggcctgaag
    33601 ctgaccttca cctgcttcaa tttcaccacc aggtaaaaac caggaaccat taggagcttg
    33661 aacaagaata atttttgttt gttcgtgatt gggaatgata gcatagacac cgtaacgtgt
    33721 gacatagtct ttatgtgcat ttttatgtcc aaatgttgga atcatcattt tatttacctt
    33781 tcctttttct tcattatact aaatttttgc taattattct tatcaatttg tttagtttaa
    33841 taaaaaattg atagaaaaag agagagtctc cttatagaaa ctctcttagc taacgttaat
    33901 cgagagactc ttcgttaaga aaagaatctc cctctttaac agctttaatc gtgatatttt
    33961 cactgtttgt catcagtgca cgtaactgtt tttcagttgg gtgttctaaa taatagtctg
    34021 taatggcatc ttcgatataa tcttgaatag tacgacggag cggccgagcg cccattttag
    34081 gatcatagcc taaatctact aatttttctt tgaccttttg tgtcacatca agatgaatcc
    34141 cattatagcc taagcgctca ttaacatctt ccagcattaa atcaacgata tgcagcaaat
    34201 gctctttaga taaagctttg aattcaataa taccatcgaa acgattcata aactctgggc
    34261 tgaagaagtt gcttaattca ccaaggacag aacttgtccg tccttctcta gcagcaccaa
    34321 atccgacaga agcttcgctt ttacctgttc cggcattaga ggtcatgata ataatggtgt
    34381 ccttgaagct gactgttcgt ccttgaccat ctgttaaacg gccatcatca agaacttgta
    34441 agaacatgtg catgacgtca ggatgggctt tttccacctc atctaagaga ataagtgaat
    34501 atggattgcg acgaacttgt tcggttagct gtccagcttc ttcatagccg atataacctg
    34561 gaggagcccc gactaatttg gcgacagcgt gtttttccat gtattcggac atgtcaaagc
    34621 gaatcatatt gtttgtcgaa ccaaagagtt caatggctag ttgtttagac aattcagttt
    34681 taccaacccc agtcggtcca acgaataaga aagaaccaat agggcgattt ggagttccta
    34741 atcccacacg gttacgacga atagccttag cgattttatc aacagcatcg tcttgcccga
    34801 tcacgtgtgc tttcagatca ttggctaagt ttacgagttg agactgttcc ttttctttta
    34861 agtccccaac tggaatatta gttttttgct ctacaatagc ttcaatggtt ttttcagtaa
    34921 tgatgggaat atcttgctca tcgacttttt gagcctgcat ttctttgtat tttgtaattt
    34981 gatcgcggaa ataagctgcg cgttcatagt cttcgtctcg agtagcttgc gccttgagat
    35041 tctcagcttc aataagacgt ttgtcaattt ctttaggatc aacaaagttg agggttagat
    35101 tcattttgga accagcttcg tccagaaggt caatagcctt atcaggaaga aaacggtctt
    35161 gaatatagcg gttagataaa tgagcggcag cttcaatagc ggctgggcta tatttgacat
    35221 gatgatagtc ttcgtatttc ggttggatac cttttaaaat cgtgatggtt tcctcaacag
    35281 aaggttcatc aactttaacg ggttgcatac gtcgttctaa ggcagcgtct ttttcaataa
    35341 tacggtattc atttaatgta gtagcaccaa cgagttgcaa ctcaccacgg gccaaggctg
    35401 gttttaaaat attaccagca tccatattgc cgtctcctgc agaaccagca ccgacaatct
    35461 catgaatttc atcaataaag agaatcacat ccttgcgatt gcgaatttct tccattaatt
    35521 tttgcatgcg ctcttcaaac tgaccacgga tacctgttcc ctgaacgagg ctaaccacat
    35581 caagacgaat cacttgcttg ccttggagtt tttgaggaac agtaccatca ataatttttt
    35641 gagccaaacc ttctacaaca gcagttttac caactccagg ctcaccaatt agcacaggat
    35701 tatttttagt acggcggttg aggatctcga taacgcgtgt aatctcttcg tcacgaccaa
    35761 taacaggatc aatattacca tttcttgcaa tatctgtgac attaatccca aactcttcta
    35821 acaagccctt tgcttgctga tttggtgttt gtggctgagc aggtcgttgt ccgttgtagt
    35881 taccaccata gcgtcctccg ccatttccat tttgccctgc ctgagtaggt ggggtatttg
    35941 gaagattacc aaaagctcta aaattattca aatcaccaaa aaagtcatca aagaaaggac
    36001 ttgtggatct atcttgtgct ctatatcctg gggttaggcc atttaaaata gaattggcag
    36061 gatcggattt catgatttga taacaatttt gacagagatc aacctgtctt tgttttccat
    36121 taacacttgt ataaagatga atagtagatt cgtttaaatt acaattttga cacagcataa
    36181 tatacctccg agggtttatc taaaagtcaa agtcatttag tcaaaaatgg tcaaacttta
    36241 tattcatatt atagcaccac ggcttgggaa atcaagtaaa aagtttatcg ctttagcgtt
    36301 agcttttaga gagtaacatg acagagtaac tttattaagt ttccaatgag caaatgttta
    36361 aaatcattga aaagagtaaa aaaagtaaaa tatcaataaa tatattactt tccttgttag
    36421 tttcccttgt tttgtgttaa aataagaggg ataaaaaacg aataggagaa acgaaatgga
    36481 atcacatttg gtgagaatca tcaatcgttt ggagttgatg gtgacagatg gcggtaatct
    36541 caagcgaaat tttgaacgcg atggtgttgt tgttgcagaa gttgcctttt caaatgatcc
    36601 tgaaaatgga cctgttttca cattgcgtga tgttgaagcg cgtgagtcat attcctttga
    36661 tagcattgac ttgattgcaa tggaaatcta cgatttatta tattaagctt gacatagtaa
    36721 agagacttgc ctgaggcagg tttttttatt gtcaaaaagt attgtattaa tattcatcag
    36781 atggtataat tatctttatt gtaatgaacc taggacttat gaggagatat aaatggattt
    36841 gtcatttttg cccaaatact gggcctactt taactacggt gtacttgtca ccattatgat
    36901 ttcagtcagc gttgtctttt ttggaaccct tattggtgtc ttggtaaccc tgattaagcg
    36961 tagtcatgtg aagccgttga cctgggtcgt taatctttac gtttggatct ttcggggaac
    37021 acctatggtg gttcaaatca tgattgcctt tgcttggatg cattttaaca atatgcctac
    37081 tattggtttt ggggttttag acttggactt ttcaagacta cttcctggaa ttattatcat
    37141 ttcattgaat agcggtgctt atatttcaga aattgttaga gcaggtattg aggctgtacc
    37201 aaaagggcaa ttagaagcag cttattcact aggtattcgt cctcaaaatg ccatgcgtta
    37261 tgtgattttg cctcaggcct ttaaaaatat tttgccagcc ttaggaaatg aatttattac
    37321 cattattaag gatagtgctc ttttacaaac cattggagtg atggaacttt ggaatggtgc
    37381 ccaatcggtg gtaacggcta cttattttcc aatttcccct ttactggtgg ctgcttttta
    37441 ctacttaatg gtcacaacag tgatggcaca gttattggca gtcttagaac gtcacatggc
    37501 gcaaggaggt aatcattgat gactgaggct attatttcaa ttaaagactt gcacaagtat
    37561 tatgggcaca atgaagtgct taagggaatt gatttagaca ttatgccagg agaggttgtg
    37621 gtgattattg gcccttctgg ttctggaaaa tcgaccttac ttcgaaccat gaatcttttg
    37681 gaagtaccaa ctaagggaca gattaggttt gaggggattg atattaccga taagaagaat
    37741 gatattttca gcatgcgtga aaaaatggga atggttttcc agcagtttaa cctctttccc
    37801 aatatgacta ttttagaaaa tatcacttta tcgccaatca aaactaaggg aatggctaaa
    37861 gcagaggctg acaaaacagc cttgagcttg ttggacaaag ttggattatc agaaaaagcc
    37921 aaggcttatc ctgctagtct ttctggtggg caacagcagc ggattgcgat tgcgcgtgga
    37981 ctggctatgg atccagatgt tttactcttt gatgaaccaa cttcagctct agacccagaa
    38041 atggtgggtg aggtcttggc tgtcatgcaa gatttggcta aatctgggat gactatggtt
    38101 attgtgactc atgaaatggg ctttgctaaa gaagtcgcag accgtgtgat gtttatggat
    38161 ggcggcgtta ttgtggaaga aggaagtcct aaccaacttt ttgatctgac taaagaagaa
    38221 cgtacaaaag attttttgag tagagtatta taaatctgtt ctatgaatta taaaaggaag
    38281 tcctaaatga tttaggactt ccttttataa tttgctaagg cattttatag gagattactt
    38341 ttctttttgt taaaataaaa agaaatagtt gcattatttg catagaagaa agggatctgt
    38401 tatggtttca gtgatgtggt ttcgtagaga tttaaggatt gatgatcaaa aagctttagc
    38461 tcatgctatt gctagtcaat caccaacctt atgtgtgttt caatttaaca aggagcaatt
    38521 aaatctgcta catagtcgga atcaatctag ttttattact agcgttttgg cttttagaaa
    38581 gttattaaaa tgtgaaggta ttgacttata tctaatgtat ggagacttaa tgacctgttt
    38641 tgagcaatta ttgacacaat taaaagactg gacagatgtg tattttaact atgatgaatc
    38701 tggatatggt cgtttacgtg atcaaaaagc agcacaattt ttcaaaaaaa atgggattgc
    38761 tgttcatacc taccaagatc actatttaca tggtagtcaa gagatcatta accaatcagg
    38821 tcagccttat aaagttttta cgccctacta taggatttgg caaaattatc cgaaagagac
    38881 tcctattaaa gtagaactat cgcaaggcag gtggttaaat cttgagacac cagatgatgt
    38941 tttaaggact gttgagagtt ttaaagatga aaaatatcag gatgttgcaa cttttgatga
    39001 agcgtcaaaa caactaaatc gatttattca agaccaatta gcagcttatc acgctaatcg
    39061 agattttcca gcgcagctag ggacgagtcg gttgtctcct tttttaagaa taggagctat
    39121 tggcattcgc acggtatatc acgctgtgcg tcaagcacca aatagtctag ggcaagctac
    39181 ttttttaaaa gaattagctt ggagagactt ttacaatatg gtctatgtgg cttatcctga
    39241 tcagaaaact cagcctatcc aaaaagcctt ttctcaaatc gaatgggtta ataatcctga
    39301 ctggtttcag ttgtggaaag aaggtaaaac gggttaccct attgtcgatg ctgcaatgct
    39361 tcagttacaa aagacaggat ggatgcataa tcgtttacga atgatagtag cttctttttt
    39421 aactaaagat cttttatgtg attggcgttt aggagagcag tattttcaac aacaactaat
    39481 tgattatgat gctgccagta atatcggagg atggcagtgg gctgcttcca ctggaacaga
    39541 tgctgttcct tattttagaa tatttaatcc tgttactcaa ggtaagcgct ttgatcctaa
    39601 aggcgagttt attaaagcgt atttgcctca actagaacac gttccagaga agtatctcca
    39661 cgaaccgtgg aagatgccaa aaaaccttca agagagtgtg tcctgtatta ttggcacaga
    39721 ctatcctcaa ccaattgtcg atcatgctaa acaacgtgaa caagctattg caaagtatga
    39781 gtgggcaaaa gaaaaagcaa aaatagaatg actgttctca ttataagagt ttaaacaaaa
    39841 agttatcatg aattaagatt atttaattta aaaaataagt tgactttatt tagattattt
    39901 gatactattc agttgtctcc cttagagaaa gcgatttctt gttttggagc tgatttttac
    39961 catttggtct tagaatagga tgagtaatat gacttacaac gaggtatatc aagaatggtt
    40021 gcacaataat gatcttagtg atgatattaa agcagattta gcagccataa aagacaatga
    40081 ggctgagatt caagatcgtt tttacaaaac acttgaattt ggaacagcag ggctaagagg
    40141 aaaacttgga gcaggcacca atcgcatgaa tacctatatg gttggtaagg cagcacaagc
    40201 tttagctaat actattattg atcatggacc tgaagcggtt aaaaagggca ttgcggttag
    40261 ttatgatgtt cgctatcaat ctagaacatt tgcagaatta acatgctcta ttatggcagc
    40321 taacggtatt aaggcgtacc tttataaagg gattcggcca acaccaatgt gttcgtacgc
    40381 tattcgtgct ttgggatgta tttctggtgt tatgattacg gctagtcaca atccccaagc
    40441 ttacaatggt tacaaagctt attggcaaga aggttctcaa attttggatg acattgcgga
    40501 tcaaattgca caacacatgg ctgcactaac tcagtatcag gaaatcaaac aaatgccttt
    40561 tgaaaaggct ctggacagtg gacttgttac ttatattgat gagagtattg aagaagcata
    40621 taaaaaagaa gtgcttggtt taacgattaa tgatactgac attgataagt cagtccgagt
    40681 agtctatacc cctttaaatg gtgttgggaa tctaccagtg cgtgaggttt taagacgccg
    40741 cggttttgaa aatgtttatg tggtacctga gcaggaaatg cccgatcctg attttacaac
    40801 agttggctat cctaatcccg aagtccctaa aacttttgca tattcagaaa aattaggtaa
    40861 ggcagttgat gctgatattt tgattgcaac tgatccagat tgtgaccgtg tggctttaga
    40921 agttaaaaat gcagtcggtg actatgtttt tctcaatggc aataaaatcg gagcgctttt
    40981 atcttactat atcttttcac aacgatttga cttaggcaat ttaccggcta atcctgtttt
    41041 agtgaaatcc attgtaacag gagacttgtc acgggctatt gctagccatt atggtattga
    41101 aaccgttgaa acattgactg gttttaagaa tatttgtggc aaggcaaacg aatatgatgt
    41161 gacgaaacaa aaaaactacc tgtttggtta tgaagaaagt attggttttt gctatggcac
    41221 ttttgttcgt gacaaagacg ctgttagcgc ctctatgatg attgtagaaa tggcagctta
    41281 ctacaagaaa aaagggcaga atttactaga tgttttgcag actatttatg cgacatttgg
    41341 gtattataat gaacgtcaaa ttgccttgga gcttgagggg atagaaggac aaaaacgcat
    41401 tgcgaggata atggaagatt tcagacagac accaatagct agtgttgcag agatggcgtt
    41461 agacaagaca attgatttta ttgatggcta tcaagatttt ccaaagcaaa actgtctcaa
    41521 attttatttg gatgatggtt cttggtatgc acttagacca tcaggaacag agcctaaaat
    41581 aaaattttat ttatatacta ttggccaaac acaagaaaat agtgcaacaa aattagatgc
    41641 tattgaagca gcgtgtcgca caaaaataaa tcaggttaat taaacatcaa aaatggataa
    41701 cacttttaca ctatttttcc atataaacaa ctacaaaagg aggtgagact tttaggcacc
    41761 ttctttttct tgtaggtgcc actaatcaat ttaatcgact caaaccaata ctaaaaaata
    41821 agtaagagta taaagaacag gcatctattt ttttgttata atagaaaaat gaaattaaag
    41881 ggagatgtca atgacagaac taattgatgg taaagcctta gctcaaaaga tgcaacaaga
    41941 gttagcagct aaagtcaaca atctaaaaca aaaaaaagga attgtaccag gcttagccgt
    42001 tattcttgta ggtgatgatc ctgctagtca ggtgtatgtc cgtaataaag agcgtgcagc
    42061 tcttactgta ggttttaaaa gtgagaccgt tagattatca gaattcattt gtcaagaaga
    42121 gcttattgca gtaatcgaac gttacaatgc agataacact attcatggta ttttagtgca
    42181 gctacccctg ccaaatcata ttaatgataa aaaaattatt ctcgccattg atcccaaaaa
    42241 agatgtggat ggttttcacc cgatgaatac aggtcacctt tggtcaggac gtcccttgat
    42301 ggttccttgt actccatcag ggattatgga attgcttcga gaatataatg ttaaccttga
    42361 aggtaaacat gccgtcatta ttggcagatc gaatatcgtt ggaaaaccaa tggcacagct
    42421 cttactggac aaaaatgcaa cagtcacgtt gacacattca agaacacgtc aattagaaga
    42481 agtatgtcgc tgtgcagatg tgttgattgt ggcaatcgga caaggtcatt tcataacaaa
    42541 acaatatata aaagatggtg cgatagtgat tgatgtagga atgaaccgtg atgataatgg
    42601 caagctaatt ggagatgtgg cctttgatga ggtggcagaa gttgcagcga aaatcacccc
    42661 tgtaccagga ggtgtcggtc ctatgacgat tgctatgttg ctagagcaaa cttatcaatc
    42721 tgctctccgt agtactcata aatagttata attagacaat tcaacataag agaatataag
    42781 aagtcagcaa tggcttcctt ttttgttttt ctgctcacta tttattcaga aaaatggtat
    42841 aattgcatta gtatgcaaag ggactatgtc aggtccaact aagtgaaagg tggcttgatg
    42901 gcagattatt taaccgtcac tcatttgacg aaatatttaa aattaaaatt tgaccgtgac
    42961 ccttatttgg aacgggttta tctgactggt caagtgtcca attttcgaaa acgaccaact
    43021 catcaatatt tttccttaaa agatgaaagt gctgtgattc aagccaccat gtgggcagga
    43081 gtctataaaa aactaggatt cgacctagaa gaaggcatga aaattaatgt aattgggcga
    43141 gtccaacttt atgaacctag tggctcttac tctatcgtga ttgaaaaggc agagccagat
    43201 ggtataggtg ccttggcttt gcagtttgaa caattaaaga aaaaattaac ggcagaaggt
    43261 tattttgagc aaaaacacaa gcagcccttg ccacagtttg tatcaaaaat tggggtcatt
    43321 acaagtccta gtggtgctgt gattcgagat attatcacaa ccgtttcacg gcgttttcca
    43381 ggggttgaga ttttattatt cccaactaaa gtacaaggtg atggagccgc ccaagaagta
    43441 gtggctaata ttcgaagagc caatcaaaga gaggatttgg acttgctcat tgtcggccgt
    43501 ggaggtggct cgatagaaga cctttgggcc ttcaacgagg aaatagtggt tcaggctatc
    43561 tttgaatcgc aacttccagt gatttcgagt gtgggtcatg aaacagacac gactttagcg
    43621 gattttgtgg cagatcgcag agcagccaca ccaacagcag cagcagagtt agcaacgcct
    43681 attacaaaaa cagatcttat gtcttggata gtagagcggc aaaatcgttc ctatcaggcc
    43741 tgcttgaggc ggattaagca acggcaagag tgggtggata aactctcgca atctgttatt
    43801 tttaggcaac cagaacgatt atatgatgcc tacctgcaaa aaattgatcg ccttagcatg
    43861 accctgatga atacgatgaa agatcgtctg agttccgcca aagaaaacaa ggttcagttg
    43921 gaccatgcct tggccaatag tcaattacag acaaaaatcg agcgatacca agaccgtgtt
    43981 gctaccgcta agcgtttact gatggctaat atggctagtc aatatgatag tcagctggct
    44041 cgctttgaaa aagcacagga tgctttgcta tcactggatg ccagccgaat tatcgcccgt
    44101 ggttatgcaa tgattgaaaa aaatcaagca ctggtagcct ctgtaagtca gataacaaag
    44161 ggtgatcagt taaccattaa gatgcgtgat ggacaattag atgtagaggt aaaagatgtc
    44221 aaaaacgaaa acatttgaag aaaatttaca agatttagag actattgtga acaaacttga
    44281 aaatggggat gtccctttgg aagaagctat ttcagaattt caaaaaggaa tgcttctctc
    44341 aaaagaactt caaaagacct tacaagcggc agaaaaaaca ctcgtcaaag tgatgcaagc
    44401 tgatggcaca gaagtagata tggatgatta atggacaaat tagctagaat tgacgaagcc
    44461 attcgtcgct actataagac gactagtaac ggtgtatctg aagagttgat tgatgctatc
    44521 ttgtattctg ttgacagtgg tggcaagcgc attcgcccac ttatcttatt agagatgatt
    44581 gagggatttg gggtatcgtt acagaatgct cattttgatt tggctgcagc tcttgaaatg
    44641 attcatacag gaagtctgat tcacgatgat ttgccagcca tggataatga tgattaccga
    44701 cgtggcagac tgaccaatca caaacaattt ggagaagcca cggccatttt ggcgggagac
    44761 agcttatttt tagacccctt tgggttaata gctcaagctg aattaaatag tgaggttaaa
    44821 gtagccttaa tccaagaact ttccctagct tcaggaactt ttggcatggt tggtggtcag
    44881 atgttagata tgaaagggga aaatcaagca ttaagtcttc ctcagttgtc actgattcac
    44941 ctcaataaaa ccggaaaatt attagctttt ccttttaaag cagcagctct tataacagaa
    45001 caggctatga ctgttcgtca acaactagag caagcgggaa tgctcatcgg gcacgccttt
    45061 cagattaggg atgatatttt agacgtgaca gctagctttg aagatcttgg aaaaacgcct
    45121 aaaaaggact tattcgcaga aaaagctact tatccaagtt tactggggtt agaagcctct
    45181 taccaactgc tgacagagag tttagatcag gctttgacga tttttcagac actagaaagc
    45241 gatgtaggct ttaagcctca aataattaca aaactgatag aagggttacg acttaatgcc
    45301 taaagaaaga gtagatgtgt tagcctataa gcaaggatta tttgagacca gagagcaagc
    45361 taagcgtggt gtcatggcag gcttagtggt ctctgtgatt aatggccaac gctatgacaa
    45421 gccaggtgac aaaattgacg atgggactga gttaaaactt aaaggtgaaa aactcaaata
    45481 cgtcagtcgt ggtggattaa aactggaaaa ggggctgcac gtttttggtg tatcagttgc
    45541 taatcaaatt gggattgata ttggcgcttc aacaggtggt tttaccgatg ttatgttaca
    45601 agatggggcc aaactagtct atgccgtcga cgttgggact aaccagttgg tatggaaact
    45661 cagacaagat ccacgagtaa gaagtatgga acagtataac tttcgttatg ctcagccaga
    45721 agactttaat gagggacagc ctgtatttgc cagtattgat gtgtccttta tttctctcag
    45781 cttgattttg ccagccctgc ataacgtttt gtcagatcag ggacaggtta ttgctctcat
    45841 taaaccgcaa tttgaagctg ggcgcgagca gattggtaaa aaaggcatcg tcaaggacaa
    45901 acagattcat gaaaaagtga ttcaaaaggt catggatttt gcctcaggtt acggatttac
    45961 agttaaggga cttgattttt ctcctattca gggtggtcat ggcaatatcg aatttttagc
    46021 tcatcttgct aagtcacaga cacctgaaac gttagccccg catttgattc agaaagttgt
    46081 tgccaaggca cataaggagt ttgagaaaca tgaaaaagag tgaacgactt gaattaatca
    46141 aaaaaatggt tttgacgcat ccaattgaga cgcaacatga cctcttaaga ttattggcag
    46201 agcatgggtt agaattaacc caggctacta tttcaagaga catgaatgaa attggtatag
    46261 taaagattcc ttctggcagt ggacgttaca tctatggtct ttctcaagat agtggaaaaa
    46321 agatcgttca aggacctaga tcgataaaga gcactatttt agctgtatct gacaaaacaa
    46381 aaggtttaga acaacacctc tatttaaaag tcgtacctgg caatagtaaa ttaatcaaac
    46441 gttatttatt agcagatttt tcaaaagcta tttttagtct tattgctgat gatgatagtt
    46501 tattgttaat tgcaaagtct ccttcagaag cagatatgat acgccaagaa attttgcttt
    46561 ggatgcaggg tataacctag aaaaaaatag gggagaaagt gatgttatta gaaatttcta
    46621 ttaaaaattt tgctattatt gatgaaattt ccctaaattt tgaaaatggt atgacggttt
    46681 tgacgggtga aactggagca ggaaagtcta ttatcattga tgctatgaat atgatgcttg
    46741 gtgcgcgtgc tagtacagaa gtgattcgtc gtggagctaa taaagcagaa attgaggggt
    46801 tcttttcggt agatgctacc ccagaactgg ttgcgtgtct ggaatcatca ggtattgcta
    46861 tggaagaaga actgattatt cgccgagata tctttgccaa tggcagaagc gtgagccgca
    46921 ttaatggtca gatggttaac ctagccacct taaaacaggt cggacagttt ttggtagata
    46981 ttcatgggca acatgaccaa gaagaattaa tgcgaccaca gctccaccag caaattttgg
    47041 acgcttttgg tgataaggct tttgagcaat tgaaagagaa ttatcagctt atttttgatc
    47101 gttataaaag cttgcgtcgc caggttattg acaaacaaaa aaatgaaaag gaacacaaag
    47161 atcgtattga tatgttggcc tttcagatag cagaaattga agctgctgcc ttgagtcgag
    47221 gtgaggacga ccggttaaat caagaacgtg atcgcttaat gaaccacaaa caaattgctg
    47281 ataccctgac caatgcctac gtcatgctag ataatgacga tttttcaagt ctatccaata
    47341 ttcgctctag catgaatgac ttactatcaa ttgagcagtt tgattcagag tacaaaggga
    47401 tgtcgacttc gatttctgaa gcctattata ttcttgaaga agtgagcaag caattatcag
    47461 ataccattga ccaactggat tttgatggtg ggcgattaca ggaaattgaa tttcgcttgg
    47521 atatactcaa tagcttaact cgtaaatacg gtggtaatgt gaatgatgtg cttgactact
    47581 acgataatat cgtcaaagaa taccagctat taacaggaga tgacttgtct tcaggggatc
    47641 tagaggcaga attgaaaagc ttggaaaaac aattggttgc tgctgcttcg gagttaagtg
    47701 tctctcgcca tcaattggcg gagcaattag aagctgagat taaagctgaa cttaaggaac
    47761 tttatatgga aaaagcagat ttcaaagttc actttaccac atcaaaattt aatcgtgatg
    47821 gtaatgaaag cttggaattt tacatctcta ctaatccagg cgaaggattc aagccccttg
    47881 tcaaggtggc ttctggagga gagttatcac gccttatgtt agccatcaag gctgctattt
    47941 ctagaaaaga agataagacg agtattgttt ttgatgaagt agatacaggt gtttctggtc
    48001 gcgttgcgca agccattgcc caaaaaattt ataaaattgg gcgacatggg caagttctcg
    48061 ctatttcaca cttacctcaa gttattgcta ttgctgatta tcagtatttt atttctaaag
    48121 aaagtaaaga agagtccacc gtttctaagg taaggttatt aactcctgaa gaacgtgtgg
    48181 aagaaattgc tagcatgatt gcaggaacag atatgacaca agctgctctt acgcaggctc
    48241 gtgaactact tgccaaacat taagattatg tttggtattt gatattttca taattagatg
    48301 acattgattt tttaggtgct aaaataatca ttgtgctaga ccatttttcc tctgttaatc
    48361 tggcttggtt tgccttgaca aacctctgag aaatagtaga atagataaga gaattttaag
    48421 ctgaggggat agaaatgact agtaaaaaag cgtgtttatc aagcatcatt gtgttagcaa
    48481 gtttaacgtg tggaaatgat actgttagtg ccaatcatct ctcagcaact ggagataagt
    48541 ttgatgattg ctcaacactt gttgaaaaag atgtggcccc taaagatgaa cttgagatgt
    48601 tagcatggtc ctcgtctcaa acaactgatg atgctgacag agactatgaa gattttctcg
    48661 atgatgattc ttttatttct caaaatgaaa ctgataagat gtttgagaat ttaactgatg
    48721 ataggttatt aaatgaatta gatgaattag atgaagaaaa tgaagaagat gaagaagata
    48781 caattgagcc agagcaaaat gtaataatgc ctagtgacga tgagctattt gatttaactg
    48841 atgctgttga gacacgcctt actgtttcta gtgctcccca tttagaggct gaattgccga
    48901 aaccacattt gaggagccta tcagatacag cactgcggtc tggtgaaatt agaggacatt
    48961 tagataacaa actggacgct ttgtctgtaa cagctacaaa gttagcatta acgatggctc
    49021 aaaaatttga tttgacaacg catgtctatt ctataggtga aagctttagt gaagtattag
    49081 ctgctcatta tgaagacaga aaagcagaat cagctttttc taagaaaaag agatttcacc
    49141 ttcctattgc tactccagat gttgttatag aggagttaag gcgcctagtc tcttctattg
    49201 gaagttcaaa agaagatgtt tcagttcctt atagtcggaa gctaggtatg gcagttgcaa
    49261 aaagaaaaat agccctgcca caaacgggag aggggttctc ttattatcca gttttacttg
    49321 gtttaatgat attaggatta acgccgatta tgataccaaa gaagataaat aattaggtaa
    49381 taagttattg tagttgtaaa agacggggca aatgttcaag cgtgaaaagg ttgacttttg
    49441 cctcgttttg tatctcgtta ttgctaaggc attttcttcg agcagctagt gctcgccata
    49501 cctatctacc gagtgattat tcaatagcac taccagtttt gctttattta gtaaggagtg
    49561 ttagaataaa gaggtgagaa actagtttag aatggaaaaa tacatgggaa ctataaaaat
    49621 tgttacagat tcatcaataa ctattgaacc agaattaatt aaagctttag atattactgt
    49681 agtaccttta tctgtcatga ttgatagcaa attatattct gataatgatt taaaagaaga
    49741 aggtcatttt ttgagcctta tgaaggctag caaatccctt cccaaaacca gtcagccacc
    49801 ggttggtctc tttgctgaaa cttacgaaaa tttggtcaaa aaaggagtaa ctgacattgt
    49861 tgctattcac ctctcaccag ctttatcagg tactattgaa gcttcccgtc agggggctga
    49921 aatcgctgag gcacctgtta cagttttaga ttcaggattt actgatcaag ccatgaaatt
    49981 tcaggtcgtt gaggcagcaa agatggcaaa agcgggtgct agtttgaatg agattttggc
    50041 tgctgttcaa gctatcaaat caaaaacaga gctctacatt ggtgtatcta ccttagaaaa
    50101 tttagtaaaa ggaggtcgta ttggtcgtgt gacgggtgtt ttgagctcgc tacttaatgt
    50161 caaagttgtt atggcactta aaaatgatga gttaaaaacg cttgtcaaag gtcgaggtaa
    50221 taaaacattt acgaaatggt tagatagtta cctcgctaaa aatagtcatc gcccgattgc
    50281 agagatagct atttcttatg ctggtgaagc tagcctggca ttaaccttaa aagaaagaat
    50341 cgcagcttat tacaaccact ctatttcggt tttagaaaca ggctctatca tccaaacaca
    50401 tacaggagaa ggagcttttg cggttatggt tcgttatgaa taatcgtcat ttatttagtg
    50461 ggatattttt ctttgttatt agtttatgtc tggccttttt attgctaaat attattatcc
    50521 ctaagtcaaa ttcacgtttg aaaaagagtg attttctgaa aaaagaacaa gtagctatcc
    50581 aatatgttgc tataggagat tcattgacag aaggagtagg tgatctaact catcaaggtg
    50641 gttttgttcc tttgttaacg aatgatctca gtgaatattt taaggctaat gttaatcatc
    50701 aaaattacgg cgtatctggt gataccagtc aacaaattct tgataggatg ataaaacaaa
    50761 agcagataca gttatcttta aaaaaagcag atataatgac gttaaccgtt ggtggtaatg
    50821 atgttatggc agttattcgg aagaatttag cggatttgca agtttctagt tttagaaagc
    50881 cagctcgtca gtatcaaaaa cgattaagac agattatcga gttagccaga aaagataata
    50941 aagatcttcc tatttttatt ttaggcatct ataatccgtt ttatttgaat tttccagaac
    51001 taactgatat gcaaaaagtg attgatgact ggaataccaa aactaaggag gttgttggag
    51061 aatacgatcg tgtgtacttt gtgccaataa atgacctctt gtataaaggg ataaatggac
    51121 aagaaggaat tgttcattct tcaggagatc aaactacaat tgtcaatgat gccttgttta
    51181 ctggggacca ttttcaccca aataatactg gctatcaaat catgtcaaat gcagtaatgg
    51241 agaaaattaa aaagcatgaa aaaaaaatca aaccttaatt ggtggaagtg gagcttctta
    51301 tgtctgcttg cttttaatac cgcctttttg atggttattg caagtcgtct cattcaagta
    51361 agagaacctg agtcagaact gattgctaaa aaaccagtta aaaatatcaa aattggtaca
    51421 tttgttacaa ccagagaaca gcttaacgaa actgtagcaa gttatcttaa agattatcag
    51481 actgaaaaaa tgtcttataa attttatgcg acatcttctt ctattttgtt tgaaggaact
    51541 tatcaattat tagggtatga agtcccttta tatatctatt ttcaacctca tcgtctagaa
    51601 aatggagctg tccaactaca ggtgatctct ttttcagtgg gaactctgcc actcccagaa
    51661 aaagatgttt tgcagtattt gaaatcaagc tacaaattgc caagctttgt taaagtgatg
    51721 ccaaatcaat cagctatcgt tgttaattta caagatatcc aaaatgatgc taaggtttat
    51781 ttaaaagcca agaaaattga tttatttaat gatgaaatca gttttaacat ctataagaaa
    51841 taagctcaaa taacgttaaa tacttgacct aatcgctttt tttagatatg ataatatctg
    51901 ttaaagcatt aagcttacta attatttgga ggatttgtta aatggctaac aaacaagatt
    51961 taatcgcaaa ggttgcagaa gcaactgaat tgactaaaaa agattcagca gcagcagttg
    52021 atgccgtgtt ttctacaatc gaagctttcc ttgctgaagg tgaaaaagta caattgatcg
    52081 gttttggtaa cttcgaagta cgcgaacgtg cagctcgtaa aggtcgtaac ccacaaactg
    52141 gtgcagaaat tgaaattgca gcttcaaaag ttccagcctt caaagctggt aaagctctta
    52201 aagacgctgt taaataattg catagataaa agcccattgt atcaagcgtt ccagcctgtg
    52261 cagtgggctt ttttgtgttc aggggggtaa aaaaggggta aaaaatttaa tagttttcca
    52321 taatatcagc tacacttgat ttcattttct ttgtgacatg cgtataaatt tgggcagtag
    52381 ttttagcgtc tgcatgtcct acacgttcca tgattgattt tagcggcacg ttattctctg
    52441 ctagacggct aataagagtg tgacggaaga tgtggctagt aagttttttt gtaattgggt
    52501 cttccaatct ttcattagct ttttttaaag ctaagttgaa tgagttagtc tgaattggaa
    52561 caccgttttt tgttgtaaaa aggtatccca tatctctata tctatgattt gtattttttt
    52621 ctagttcgtt cataaattct aactcttgta gaatttcaag ttctctactt gtcatgatgg
    52681 tttcacgata agaagctaat gtctttggtg ctgtcttttc cccgttacga tatccttctg
    52741 tatgatcaaa tgttccgtgc aactgcaata ttcttgactt agattcgtag ttgcacggct
    52801 caatgctgac agcttcaccg atacgacaac cgttcaaact gataaactca gccaacaaac
    52861 caagacggta agtgctaggt cttctgtaca attctttcaa taatggttta atttcatctt
    52921 cttcaagata tttttcttca gcctttttcc agtcttcaag agttttcttt acccttggga
    52981 gtttagcacg tcttgcagga ttatcttgga taatatccaa accaacagca taatcaaatg
    53041 ctaagtttag catagactta ttacgctctt ttttattcct agagcaatct aggttatcga
    53101 gataattctg aacgtattta ggatcaatat tcactacttt aacacctatt ccaaaagttt
    53161 cccttatctc ttcgatgtta cccctcagag aagctacaga cgacctttta agttctttct
    53221 tataaaacgc ccaccattca tctaaaagtt ccgtgaaaag taactcagag gcctttaatt
    53281 gcgctatttt ttctgttatt ttttgttcaa ggatttttcg agctgcttta taagctcttg
    53341 aattatcctt ctccatagta acggatacag gtttccatgt tccagtgtaa ggatctttat
    53401 aattttcacg aaatttgaat ttaccgttat cagtttcttc tatccacatt tgttttttac
    53461 ctcatttttt gttaaaatga gtataagaaa acgacctatt taatggttgt ttcttatact
    53521 agatccgcct cacgctcgca ccgaccaaag ttgaacgtgt ggctttttta ttttacttga
    53581 ttttctcaaa taccattgta gcttgtattc tatctccgcc accaaatcct ctactgccac
    53641 catttgatgt ggtaatagtg tgtaggcgat atcctttttt tgcttgctta ttaataacat
    53701 tttcaagttc agttaaattt cctgagcctg ttcctataag cttttctttt agtgtaactt
    53761 gtagcacaac atattcataa ttttcgccag aagcagttga aacagtacta gcttctttta
    53821 cattgtccaa aaatcccatg ataatctcct ttaacctatt aaagtataat attcatcaat
    53881 aaccatgact tcatcggtcg tggtctttaa attatgtctt tgcataaaag acaagtagtt
    53941 aaactcatgt ttgtcttcta ctttgtcaaa ttcatcttca agcaaacacc tgatcatatg
    54001 tctatttgcc tgcaattcaa attcttcatg acgcctttga tattggccag aatcatgttc
    54061 aatatgtcct agttcatgaa aaataacttt cttttttgac tcatcggata atgctctatt
    54121 aacgaagaca acttttattt catcaatata gattcctgga cgtggccata gttcattatc
    54181 gaaataagct aattctacat tatggaagtc taaaatctcc tcaatagtca tagactatct
    54241 tcccttcaag taaatttcaa taatattttg tattgcttca atatctgatt cagtaagcgg
    54301 cttaccatcg aacgttttgg cgtttttggc catttttcgt agatcttcag aagtgtattc
    54361 ttggttatct tttgcaattg cagggttatc agtgcgacca agcaagtaat ctgttgagac
    54421 gtggaaatag tctgcaatct cttgtaattt ttcagaacct ggtttgtttc gttttaaagc
    54481 atagatggta tttcgactat accccatctt ttcttctaga gaatttattg aaagaccttg
    54541 ttttttagca agttctttta tcctttcaaa tgttataaac actgatttat caacctttct
    54601 ggaggatgac aaaaaatatt ttaaagaatt tcaataaaaa ccgttgactt tttacggaga
    54661 atactctaaa atagtttttg taagatagtt agttagtaaa aaacgaagtt aaacatttta
    54721 caaatctttt taaagtagtt ggggaaccgc gtaatat
//
LOCUS       DAUGQX010000004        54242 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUGQX010000004 DAUGQX010000000
VERSION     DAUGQX010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54242
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.004"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(293..656)
                     /locus_tag="VIA51_000196"
                     /pseudo
     CDS             complement(293..656)
                     /locus_tag="VIA51_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1077..1610)
                     /locus_tag="VIA51_000197"
     CDS             complement(1077..1610)
                     /locus_tag="VIA51_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEQ8682174.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1690..2466)
                     /gene="recX"
                     /locus_tag="VIA51_000198"
     CDS             complement(1690..2466)
                     /gene="recX"
                     /locus_tag="VIA51_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEQ8682175.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2581..3936
                     /gene="rlmD"
                     /locus_tag="VIA51_000199"
     CDS             2581..3936
                     /gene="rlmD"
                     /locus_tag="VIA51_000199"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8682176.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIISKWYKQGYRADAVIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            4601..5956
                     /gene="rocA"
                     /locus_tag="VIA51_000200"
     CDS             4601..5956
                     /gene="rocA"
                     /locus_tag="VIA51_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEQ8682177.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRRLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLEVVDFTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQDDSQSVFAIPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(6057..8762)
                     /locus_tag="VIA51_000201"
     CDS             complement(6057..8762)
                     /locus_tag="VIA51_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEQ8682178.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKKYHFGQRFPKEVYQEAQEYLARLSQ
                     SFQIIDTSGQVRPEAEILGTSIAFDYDLPKRSFREPYFAIKVRLRLPITLPAMSWKTL
                     ALKLGNETTPSETVSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPNHDQPFYADQGTIKLNIISNTAQVAELEIQQTFAIPISADKLLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(8777..10063)
                     /locus_tag="VIA51_000202"
     CDS             complement(8777..10063)
                     /locus_tag="VIA51_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEQ8682179.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANEKGHQTDHTQMNPWIWERKYEIDCLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCTKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            10196..11236
                     /locus_tag="VIA51_000203"
     CDS             10196..11236
                     /locus_tag="VIA51_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8682180.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            11287..12981
                     /locus_tag="VIA51_000204"
     CDS             11287..12981
                     /locus_tag="VIA51_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8682181.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDTPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKISEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGNKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLAVAKEEGLDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQPGYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVAELVERVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            13005..14447
                     /locus_tag="VIA51_000205"
     CDS             13005..14447
                     /locus_tag="VIA51_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8682182.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDAIPVISPSWSPEWYYDPYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(15058..15936)
                     /locus_tag="VIA51_000206"
     CDS             complement(15058..15936)
                     /locus_tag="VIA51_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8682183.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            16132..17082
                     /locus_tag="VIA51_000207"
     CDS             16132..17082
                     /locus_tag="VIA51_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8682184.1"
                     /translation="MIRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            17092..18018
                     /locus_tag="VIA51_000208"
     CDS             17092..18018
                     /locus_tag="VIA51_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8682185.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            18099..19544
                     /locus_tag="VIA51_000209"
     CDS             18099..19544
                     /locus_tag="VIA51_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8682186.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            19850..20455
                     /locus_tag="VIA51_000210"
     CDS             19850..20455
                     /locus_tag="VIA51_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEQ8682187.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            20445..22169
                     /locus_tag="VIA51_000211"
     CDS             20445..22169
                     /locus_tag="VIA51_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8682188.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADKVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESVADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDYLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            22169..23653
                     /locus_tag="VIA51_000212"
     CDS             22169..23653
                     /locus_tag="VIA51_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682189.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDCILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            23583..27089
                     /locus_tag="VIA51_000213"
     CDS             23583..27089
                     /locus_tag="VIA51_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEQ8682190.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWITAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYADGKDYDRLHEEHSDWLLYGSET
                     VSAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLQVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKASTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSLVKKAFSMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            27227..28105
                     /locus_tag="VIA51_000214"
     CDS             27227..28105
                     /locus_tag="VIA51_000214"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8682191.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            28340..29095
                     /locus_tag="VIA51_000215"
     CDS             28340..29095
                     /locus_tag="VIA51_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEQ8682192.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQASALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            29148..29486
                     /locus_tag="VIA51_000216"
     CDS             29148..29486
                     /locus_tag="VIA51_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8682193.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            29488..29793
                     /locus_tag="VIA51_000217"
     CDS             29488..29793
                     /locus_tag="VIA51_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8682194.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(30228..31301)
                     /locus_tag="VIA51_000218"
     CDS             complement(30228..31301)
                     /locus_tag="VIA51_000218"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEQ8682195.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(31357..32109)
                     /locus_tag="VIA51_000219"
     CDS             complement(31357..32109)
                     /locus_tag="VIA51_000219"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEQ8682196.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(32351..32421)
                     /locus_tag="VIA51_000220"
     tRNA            complement(32351..32421)
                     /locus_tag="VIA51_000220"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32387..32389),aa:Thr,seq:ggt)
     gene            32588..32842
                     /locus_tag="VIA51_000221"
     CDS             32588..32842
                     /locus_tag="VIA51_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEQ8682197.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            32860..33255
                     /locus_tag="VIA51_000222"
     CDS             32860..33255
                     /locus_tag="VIA51_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEQ8682198.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            33531..33859
                     /locus_tag="VIA51_000223"
                     /pseudo
     CDS             33531..33859
                     /locus_tag="VIA51_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            33856..34419
                     /locus_tag="VIA51_000224"
     CDS             33856..34419
                     /locus_tag="VIA51_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8682199.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTQLTAAETAQLIIQKMTHIKEN"
     gene            34421..37069
                     /locus_tag="VIA51_000225"
     CDS             34421..37069
                     /locus_tag="VIA51_000225"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEQ8682200.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDDWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEDAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFNSNINYIKCFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            37223..39631
                     /locus_tag="VIA51_000226"
     CDS             37223..39631
                     /locus_tag="VIA51_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEQ8682201.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKTKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGVSHFLS
                     AKDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSA
                     SFYF"
     gene            39764..40492
                     /gene="cas5c"
                     /locus_tag="VIA51_000227"
     CDS             39764..40492
                     /gene="cas5c"
                     /locus_tag="VIA51_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEQ8682202.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            40492..42387
                     /gene="cas8c"
                     /locus_tag="VIA51_000228"
     CDS             40492..42387
                     /gene="cas8c"
                     /locus_tag="VIA51_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEQ8682203.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QIQYDSFHKQLNNWIDYCEEGDVKKFLTFVQQFILKPEFLTLILDSLIGPDYQHNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEEDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            42392..43240
                     /gene="cas7c"
                     /locus_tag="VIA51_000229"
     CDS             42392..43240
                     /gene="cas7c"
                     /locus_tag="VIA51_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEQ8682204.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTL
                     EILEGL"
     gene            43242..43916
                     /gene="cas4"
                     /locus_tag="VIA51_000230"
     CDS             43242..43916
                     /gene="cas4"
                     /locus_tag="VIA51_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEQ8682205.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            43913..44938
                     /gene="cas1c"
                     /locus_tag="VIA51_000231"
     CDS             43913..44938
                     /gene="cas1c"
                     /locus_tag="VIA51_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8682206.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSSALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            44949..45242
                     /gene="cas2"
                     /locus_tag="VIA51_000232"
     CDS             44949..45242
                     /gene="cas2"
                     /locus_tag="VIA51_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8682207.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   45391..45685
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45458..45488
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaa"
     gene            45845..46555
                     /gene="ccdA2"
                     /locus_tag="VIA51_000233"
     CDS             45845..46555
                     /gene="ccdA2"
                     /locus_tag="VIA51_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEQ8682208.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            46568..47191
                     /locus_tag="VIA51_000234"
     CDS             46568..47191
                     /locus_tag="VIA51_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEQ8682209.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            47234..48340
                     /gene="msrB"
                     /locus_tag="VIA51_000235"
     CDS             47234..48340
                     /gene="msrB"
                     /locus_tag="VIA51_000235"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8682210.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKSDMEAKGYGYLLSSVE"
     gene            48428..49168
                     /locus_tag="VIA51_000236"
     CDS             48428..49168
                     /locus_tag="VIA51_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8682211.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            49165..50898
                     /locus_tag="VIA51_000237"
     CDS             49165..50898
                     /locus_tag="VIA51_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8682212.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSS
                     KKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLVLRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMH
                     ELMADDTQENE"
     gene            50971..52050
                     /locus_tag="VIA51_000238"
     CDS             50971..52050
                     /locus_tag="VIA51_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEQ8682213.1"
                     /translation="MSLATDYFSRQTPIVEKLMAYGFEKRDNGYFYNERFMEGEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEATP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            52064..52780
                     /locus_tag="VIA51_000239"
     CDS             52064..52780
                     /locus_tag="VIA51_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEQ8682214.1"
                     /translation="MVEFVADQSFWELFPGAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(52946..53419)
                     /locus_tag="VIA51_000240"
     CDS             complement(52946..53419)
                     /locus_tag="VIA51_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8682215.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            53561..54241
                     /locus_tag="VIA51_000241"
     CDS             53561..54241
                     /locus_tag="VIA51_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8682216.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
BASE COUNT        16285 a         9946 c        11766 g        16245 t
ORIGIN      
        1 ctatttagta actttggtta aagtaatcga actaacttgg ttgattgtat tttaatgata
       61 aaaagcttaa atttgttgta taacaaattt aagcttttta ttgtttattt ttaattgcag
      121 attggggttt aaaagacact ttacaatgct ctcaagtcat gtgttgttgt aggttgtatg
      181 catatattac aaatcccatt ataaaagaaa ttgtttaatt aatggatagt aatggatggt
      241 atggagatct taatgtggtt ttaatggtaa ttttagcagt tatagtaaga caaaaggtga
      301 cttggaaaag tttatgcaga cgattcttaa ctcccacaat atcttctgtc agattttatt
      361 agacttcttc tcagtgtcat ttttgtctgt tttacgaacg tgcaggctat tcaattgctt
      421 cttagtttct aaaggattaa accgagtata agcgtagcca ttatctgcga aaaaacctga
      481 agacgacgag aatagacatt aatcgtttta aggataatct cagggttatg gacggttttc
      541 aagtttccaa gaagatgatt gaggccgatg gtatcgtttt gtcttgaatg attccttatt
      601 ttagtggttt cattttcaat acacgacgtc aagcgtccta catactttga taaaattcta
      661 cctaaaagag gtgtcttgtc agttttggtt acaacatcaa gtgccaaaag actttgcgac
      721 ttaacaagac acttctactt taacgcaaag aaaaagtagt gagtactctc tttcgtcgga
      781 gatttcctcg ctactaaact tagtattttt tgatactttc cttaggtagt gcttaaggca
      841 gcgactttct ttggaattcc atgccttatt tttgagatcc taggctcaaa aatgccaagt
      901 ggcgtcaaca ttaacattga cgccactttt accacaacga aaaacatctg ttttggctca
      961 ctccacacgc agaaatagga aattggatgt caaatcagca gagctgttca tgctttttga
     1021 gcctaaaact gagtttgtct gcgttctgag cactccttgg gagtgctgga caactcttaa
     1081 cgattcttca gttcaagata acgtttgtac caaatagtga tataggcctt ggaaaatggt
     1141 cctttttcat gattaatcca atcaaccaat attttgacat tttcttttag gataaagtcc
     1201 atatcggctg aatactgcat ctctttttta tgaatctcgt attcatcaac atcaagtaat
     1261 ctcttttcac catccgcaaa gactttgaca tctaaatcgt aatcaatgta tttaagggcc
     1321 tcagtgtcca tcatgtatgg actagctaag ttacagtaat aagagacgcc attatctcga
     1381 atcatggcta taatgttaaa ccagtatttt ttatgaaagt aaacgattgc aggttcgcgg
     1441 gtcacccatc gtctaccgtc actttctgtg acaagagtgt gatcattaac tccaatgagg
     1501 gcattttcag ttgtttttag taccatagta tcgcgccaag tacggtgcaa actaccatca
     1561 tgcttataac tttgaattgt aataaagtcg ccttctttag gtaatttcat gccttaccaa
     1621 ctttctacaa ttaaacttat cctctatagt ctatcataaa tgtgtgaaaa aatcacttct
     1681 tttgtcagtc tataaataat ttcttaactt gcaattaatg tcgtcgctgt tgtagccttt
     1741 tcggtagaga gcctgataga gcttttgctt taaggtataa ccatcatatt tgcgactgag
     1801 tttacgatat tgtttgtcta attctttgtc aagaagatct tctatttctt gattatcttg
     1861 gtcaaaatta aggtgattga ggctatgttt agctagatcg tatgaaaagc ctttggtcag
     1921 taatgcttgg gtgattttat ctttcaaggc ttttggtggc aatttttctt gatatttgtc
     1981 aaagagtttt tggcttactt tttgagcgag ttggctaaag tcagtttgag ataagatagg
     2041 atcaatgtca tgacttgcaa tgcctttttg taataatttt tgttttaaga cttggggacc
     2101 tttatcacca tttaactgat tttggcgaat gtaggtatca gccaatttgg tgtcgtctat
     2161 ccattgttct tcttggagtt gagtgatgat gtcagcaata atgtgttctt caatctcatg
     2221 cttgcgcagg taatcagcaa cttgcttgtt gctgcgttgt tgaaaggaaa gaaaataaag
     2281 ggctaaattt ttgccgtagg acagttgggc aaaatgtttc atgtcttcaa gctgatcatt
     2341 gtcaaggact ttatctttac tcaacataaa ccgaacaata gtatcttctg ttacataaag
     2401 ggattcgtca ttatccaatt cgataaggta gaggcgtttt ttcttttcaa ttttagtgat
     2461 tttcatactt tgattatatc aaaaatggta aaatagaaga cgaaaatact gctaaaaatg
     2521 tgttgcttgt gagtgctttt ggtggtgaga ttaggatact agaggaagta aggggaagag
     2581 atggtcgtaa aggttaaaca gaaaattcct ttaaaaatta agcgaatggg aattaacggt
     2641 gaggggattg gtttttatca gaaaactttg gtatttgtcc ctggtgcttt aaagggagaa
     2701 gatatttttt gccaaatcac ggcggttaaa cggaattttg cagaggccaa actgttaacg
     2761 gtaaacaagg cttctaagaa tcgtgtcaaa ccagcttgtt ctgtttatga aacttgtggt
     2821 ggttgccaaa tcatgcatct agcctatcct aaacagctag atttcaaaga tgatgtgatt
     2881 aggcaggccc ttaaaaagtt caaaccaact ggctatgaac aatttgagat tagaccgact
     2941 ttaggaatga aaaagccaga tcactatcgg gccaaattgc agtttcagct gcggtcattt
     3001 ggcgggacgg tcaaggctgg tttattttcc cagggaagtc atcgcttggt tcctattgac
     3061 aattgcttgg tacaggatca actaacgcaa gatattatca ataagattac gcagttagtg
     3121 gacaagtaca agttgcccat ttacaatgag cgcaagattg ctgggattcg gacgataatg
     3181 gttcgtaagg cacaggctag tgatcaggta cagattattg ttgtgagtag caaagaagtt
     3241 aggttagcga atttcattgg cgaattgact aaggcatttc ctcaggttaa aacggttgcc
     3301 ttgaatagta atcgttctaa atcgagtgag atttatgggg acgaaacgga aattctatgg
     3361 ggacaagagg cgattcatga agaagtttta gactatggat ttgcgttatc accgagagct
     3421 ttttaccaac ttaatccaca gcagacagaa gttttgtatg gtgaggtggt gaaggccttg
     3481 gatgtaggga gcaaagatca tattattgat gcctattgtg gggttggctc gattggcttt
     3541 gcttttgcag ggaaggtcaa gtctgtgcgg gggatggata ttatcccaga agcgattgaa
     3601 gatgcacaaa aaaatgccaa agccatgggc tttgacaacg cttactatga ggcagggaag
     3661 gcagaggata ttatttctaa atggtataaa caaggttacc gcgcggatgc cgtcattgtg
     3721 gacccgccaa gaactggttt agatgataaa ttattaaaaa cgattcttca ttaccagcct
     3781 aaacagatgg tttatgtgtc ttgtaatacc tccactttgg cccgcgactt ggtgcagcta
     3841 acaaaggttt acgatgttca ctatatccaa agtgtagaca tgttccccca tacagctagg
     3901 accgaggctg tcgtgaagtt acaaaaacgt gtatgattga gtggcaataa caactcaagt
     3961 tttataagct caggtaatgg gtttgagcaa tagcttgaca tagtagggat gtcaaaaacg
     4021 gtttactaag catagtcata ttattgataa ctctatgttt attttagaaa cattcatggt
     4081 taaaaaagtt tgttagtttg tcactaagta gggtctattt gaagagcaag tacacacaga
     4141 caatattagg ataattggtt gttgaaaaaa agctgttttt tgctataaat tagaaaactg
     4201 agtggtcagg aggttacatt accagaagtt attttagtat gctaatatga acgatgatat
     4261 agaggattta tcctgattta atcttttaag ctgtaagaaa cctttgcaaa aactgtaggc
     4321 tgtgtgagtc tttatgtgtt agatattaaa gataaatgca acactttttt ataatgagat
     4381 caacaactga taaatctgag ttgataacca gtaaaatgat cggaatgtag aaaagttact
     4441 taatcaagct tttcgtaatt taactgttag aatgacagaa cttatgataa aaaaaagaat
     4501 atgattaaaa tgaaaaagct cagtttatct attacggagt tcgaaatgaa aagaaaatcg
     4561 agatgtgata acatattttg aacgagaagg agaaggataa atgttagaag attttcttca
     4621 atttttagga tttatatttt tagatattat tgaaattatg ttaacgttaa agctttttag
     4681 ctttgtaagt gcaattccgc ttcgcctgaa aaatattttt tatttatcac ttagtatggt
     4741 tttgtttcaa gtagtttttt gggctttctt tccagaccat ttcattcttg atgttgtgat
     4801 gttggctcag tttcttttct ttgcgcttat agccctatac tatggtaaat caataaaagc
     4861 taagttttta atgttttatg ccttttttcc actagtgtct attagtttgg ttaagcgatt
     4921 tattgtattt tttgttatgc cattgtttgg tatgccttat tcagttgtta aacataatac
     4981 actactgatt tacagcatta cttgttttag tatttttttg atttatcgct gcattcaagt
     5041 ttttcatttc gatttttcaa cctggcgcca atattttcaa tcacatagag ctagtaaact
     5101 attagtgttt actaactctt cgatggctct atattacttg tgtgtccaag ggatagatgt
     5161 gatgtcgcct tctttatcag gacttgctac aacgactgct cgttcaatca tagtgctctt
     5221 ttatttcatt ttgtttctta ctttattaat tcatttagag cgttatgtaa aacaaaactc
     5281 tattgaggca attgtgcaac aaaaagaata tcgtgagctg attaattata gtcagcacct
     5341 tggattgctg tatcaagata ttcaagagct taggcggcta ttaactaccg tgtctagtcg
     5401 tcttaagatt ggaatcgaac aaaatgatat ctctattgtg agacttactt atgaaggtat
     5461 cttgaatgct gaaaagaata atgctaaaga tgacagactt gatttaactt gtttagataa
     5521 attacaagtt gaagcaatca gacatattgt tttagctaaa ttaattgagg caaaaaataa
     5581 gaagcttaag gttgaggtat cgatccctaa ttgtattgca acgttttttc tagaagtagt
     5641 agatttcact aagctattgt catttttgtt agataatgct atagaaatga gtttggagac
     5701 aaagcaacct tgcttatcaa tagcatttct ggatcaaaac cataaacttg tcatagtcat
     5761 tcaaagcagt actaaacaag gacaagatga tagtcaaagc gtgtttgcta taccggcttt
     5821 gaaaaaaaga gatgactggc aatttgactt aaggaatgtc acgaccattt taaatcgtta
     5881 tgactatctc acaattagct cgcagattca tgatggcatt ttaacccagt taatagaaat
     5941 agctaagcct gactgatgtt aaaggtatga ataatcactc aaaatcaact taagagtctg
     6001 agacaatagt cccagactct ttttgaatat gttaatctat tactaatgat aatagtttat
     6061 tgtttcttcc aagctagagt taaaatttcc gctttgccaa gttggctggg tgtgctttgc
     6121 ttgctgtctt tttctaacaa attagtgacc ttggcattgt agtttggcag gcttaggcta
     6181 aagtcacaag ttttatcgtt tgagagatta tagctgcgcg tgataagggc attgtctgct
     6241 aagcgacgtt tgaaagctgt gagggcaact tggtcgtttg tacccgtcaa atagctatat
     6301 tctgcggcta atgttccctc gtgttggttt gtttgtgtgg taataacagg gacttggcct
     6361 tcttgagctc gccagtagct ggcaaattgt gtttgcttag tgatgctttc aaaactataa
     6421 gaaaggctgt gtttgccaag acactgggct tcaggtgttg ggaagtaacc ccagtcgccc
     6481 atttcgccaa cagaacgtaa gagagtgatg gcaatggtgt tggtatctgg taagatctca
     6541 tattcgttga ggccatagtt accaatagtg actccatttt caccatcaaa gagactcaca
     6601 aagcattctt ggtgctgtgg gttacttgga ttcttccaaa aggtggcatc tggatgattt
     6661 ggacgtttga cagtttcaaa aatactgtca gctagatgat ggtctgtttt aaggtgcgtt
     6721 gggaatagga cgcgcaagcg atgattagtc atttggttat caaaacgtgt ggtgaattgg
     6781 aggcgaggat tatttttctc catgcggata agggttgtta aggttagctc agccttttct
     6841 tgtgaacgtc ttgcttggcg ttctgtgatg tcaatgacag cctccatctc agcctgtaag
     6901 agcttatctg cggagatagg aatggcaaag gtttgctgga tttcaagttc agcaacttga
     6961 gcggtgttgc taatgatgtt aagcttgatg gtcccttgat ccgcatagaa aggttggtca
     7021 tgatttggct ggcgagaaat atattcattt ccaatatcgc cacaatcttc aaaccgcaac
     7081 aggtcttgat agattagtcc agattgttta tcggtgatgg ttagacgacc atcggtttgt
     7141 atcataactt ttagaaaccc attttcaagg cactgattac tgtcatcgta gagggaaacg
     7201 gtttctgaag gagttgtttc atttcctagc tttaatgcta aggttttcca agacatggct
     7261 gggagagtta ttggtagccg taatctcact ttgatggcga aataaggttc gcggaaggat
     7321 ctcttgggca aatcgtagtc aaaagcgatg cttgtgccta aaatttctgc ttcgggtctc
     7381 acttgtccac tagtgtcaat aatttggaaa gattgggaga gtcttgccaa atattcttga
     7441 gcttcttggt aaacctcttt aggaaagcgt tggccaaaat gatatttttt ccaggtcagg
     7501 ctgagctcag caacacttgt tttggaatgg ccgctggtat taaataagac gaagggttgg
     7561 ctatccattg gaaaatccct ggtatcaatg gcgtcagcaa tttgcttagc agcttctttt
     7621 gctaaatagt gtccgacttc ataggctttt tcaaagcgcg tcatcatttc ccgatgaacg
     7681 ctatcaacac tacaaccaca gatagaatca tgagggtgat tttgcatgag ggttttccaa
     7741 gcgtaacgca gttggtcgtg agggtaggta cttgttacct cataagccat tgctgctaag
     7801 ggttcggtga tgttttcgag ttggcgagag actctggtat tagcctgttt gaggtaaata
     7861 cgagcagaag ccgtgttagc tagggtatac cagccatcgg tttcttgact ggtaatctct
     7921 ccttggacgg ttgaaaggtt ctctggtaaa tcatctgcga gatcagccaa gtaatcttca
     7981 aagcaggaat gcacaaattc gtagtcagga tagagttggt tggctaaggc gattgccttg
     8041 gtgacatcaa gttgtacggg ttgatgatca cacccgttca tcatcagaag gtgcttggtt
     8101 gaggcgaagc gttcggcatc agcaagtttt ttatcccaaa aaagacgcgc ctcagcttct
     8161 gttgtcggga tctcattgcc attgctgtac cagttggcga agaggagtcc aagaatacga
     8221 ctgttatctg ggccttgcca actgatttca gagaattggg agctgtattt ttcactggta
     8281 tccacctgat tgttaaatcc agttggacga atgccacgac caaaggcagc agcttgtagg
     8341 ccggctttta acatcagctg tggtgtttgt cccatatttc caaaggtatc aggaaaataa
     8401 ccaagtggca cactagcgcc ccatctgtca caatcttcct taccaatcag catattgcgc
     8461 acattggatt cactgctggt caaaaaatcg tcctgtaaga tatagaaagg tccgatacgg
     8521 agttttcccg aagcaatggc ttgtctaatc tcaggttctc gttcggggcg tacttttaaa
     8581 taatcatcta ggataatggt ttgcccatcc aaatgaaaac tatgaaaatc aggatccgtt
     8641 tgaaaaactt ctaacaggtc atctattaag ttaatcagac gcatgtggtg ttgttcgtaa
     8701 gccatgtacc actcgcgatc ccagtgactg tgtgaaataa tatgtacttt tttagttgcc
     8761 atagtggcct cactttctaa ggagcaatac taaagcccag atagtcaaga agtagttcac
     8821 agaacatcat gttagcccaa gagaaccact cacgagtgta ttgataagga tcattgacat
     8881 cgaaaccctc gtgcattaag tgggtaccag catctgttgc cacaagcaaa tcaagcatct
     8941 cttttttact gtcttggtca agagcggtca atccttgtaa ggcaagggcg atatgccaga
     9001 tataattttc tggtgtatgg gaagaaccga tgcctgctgc tgcatttccc tgataataat
     9061 aagggttttc ttggctgaga atggtgcggc gcgttgccag atagataggg tcatctttag
     9121 tgcaaaaacc aaggtaaggt gcagcaagga ggcttggaat attagcatca tccatgatgg
     9181 aaaactgtcc cagaccatcc acttcataag cgtaaatggt ttctcccttg ctgttttgaa
     9241 caagggcatg gtctgcaata cccgattgaa tagcttcttt cagctgcttg gcacgagtag
     9301 ctactggttc attgtgaaaa aggttgttat ataaatcttc tagataggaa agcacaacca
     9361 ctgcaaacat atttgaagga atgaggtaac catattgaca agcatcatca cttggtctaa
     9421 agcctgacca ggtcatccct gttggtgcga caggacttcc ttttccagca tgtgttaggg
     9481 tatcttcttt gcgccaagta tcgcgttcaa acaagtaagg ggactgggcg tggtcttgct
     9541 caactgtcca taggtcaaga atgagttcta ccccacgatg aaaatcgtca ttaaactgat
     9601 cggtgcttcc tgtttcacga tagagcagat aagccagttg aatagggtag caaaggcaat
     9661 caatctcata tttgcgttcc caaatccaag ggttcatttg ggtatgatct gtttggtgtc
     9721 ctttttcgtt agcttcttcg ttgaaggcat tggcataggg atcgatacaa atgtagcgga
     9781 attggcgttt gaccagaccg gcaataatct ttctaatttc ttcatcttcc ttggcgagga
     9841 agaggtaagg tttcatttgc gcagtggaat cacgtaacca catggcagga atatcgccag
     9901 ttaaaagaaa gctagtgcca tcttcgtagg tttttagggt tgtctctaag gtattggtaa
     9961 agctggtttt gaaattaaga gcccaatcag ggtgttggtc tccacaaagg ctttccacct
    10021 tggccataaa ttggctgacg ctagttggga ttggtcgtgt catgtcatat cctccaaaat
    10081 gatatatcat ttatcttcgg tttcattata aatgataagt taaactttgt ctataggttt
    10141 ttgaaaaggt ttacaactct tttttgacat gttatactga taacaggagt aaagaatgac
    10201 aaaattatta tacaaaaaga tatatcattt cattaaagag cagatagcat caggtcgttt
    10261 gcaaattggt gaccgcctac ctactgaaaa agaattgtca gaacagttct cggttagccg
    10321 tatcacttct aagcgagcgc ttgtagaact ggagcaagaa ggcttgatta cgagaagtcg
    10381 tgggaaagga agcttcgtag ctaaaaagca agtgacgtcc cctgaagcga ataaggattt
    10441 attgttgatt cttccttttg cttctgatta tgaattggga gattatgcta agggaattat
    10501 gacctccatt gctgaaacag gttaccgtct catggttcaa ttggccagta cagtaaggtt
    10561 agacaccctg tcagactatg ctgggattat ttattatcct gaagatgtca atcacagtat
    10621 tgatttcctg ttttactgcg accatcatca cattcctcta gtcttgttgg ataaatctct
    10681 agatcttttt cagtttccgt ctgttgtagc ggataataaa ggcggtgcct gtcaattgac
    10741 tcagcacttg attgagcaag gctgtgacca gattagtttt gtggcaacag gctcttttgg
    10801 agaagtatca tccgttagag accgttattt gggttactta gcggcaatgg cagaatcgtc
    10861 tctaaaatcc cattattttc ctaagacaga gactgaaaca acagatgctt atttggaccg
    10921 tttggtgaaa accttatcgg agacgacagc cactaaaagg gggcttgtcg tggaaaacga
    10981 ttggttggct attcagctga ttcaaaaaat cacacaggta ggcttatcta ttcctgatca
    11041 agtcgctatt gtaggctttg ataatagtca agcctcccgt ttgttgagtc ccaaattaag
    11101 cacagcagct caagattttt accaaatggg gcaagaagca gctaaagtct tgttgcagat
    11161 tattcatgag ccagaccaag cagtggtgtc ttgccagtta cctgttcaag tatttatcag
    11221 agaaagtagt cactaaaaaa gacgttacta gcatgagctg gttagctcag gtaaaggaga
    11281 ccagaaatga ccatttatca cgccttaaag gattatcaag aagtcatgac aagaggagac
    11341 tatcttgtct ttgacacgcc attgacttgc cgatttattg gccgtttttt ccgctttgaa
    11401 aatcaaaaag ccctgctggc agaattggca acgtcaaagt attttcagtg gattgaagaa
    11461 ggccaagcag aggtgacgat gaaacacttt tttaaccgtc agctggctaa ggatgccttt
    11521 accctgaaga tttcagaaga taaggaaatc attattgaaa gccaaaacct tagaggtttt
    11581 cgttacgccc aagaagcttt gcttaaagtc atgaccttca aaggggataa actttatttg
    11641 cccattgttt ctgtcaagca cagcccttct tttgctatgc gggggataat tgaaggcttt
    11701 tacggaacac cgtggacacg agaagagcgg ttagattgcc tgcgttttat tggaaataaa
    11761 aggatgaata cttacatgta tgctcctaaa gatgatgatt accaacgaaa actgtggcgc
    11821 gatctttatc ctgaggattg ggtgacttat ttcaaagagc tacttgcagt agccaaggaa
    11881 gaagggcttg atttttggta tatgattagt ccggggcttg attttgatta taccaaggaa
    11941 gctgactatc agttgctcta tcaaaaattg caacaacttc tagcgttagg tgtttgtcat
    12001 tttgggcttt tgctggatga tattgactac caaattgtag atgctgttga gagacgattc
    12061 aaaaagactg cctatgccca ggcccacttg gcaactgagg ttcatcactt tttaaaccaa
    12121 caacatgcgg cgccagaatt ggtgatctgt ccgacagaat acgacaacca ccatgattct
    12181 atctatttgc aagagctgtc agaaaggatt cctaaagaag tcgccttttt ctggacaggc
    12241 ccaagcacgc tagcgagtca aatctcgcaa gcagatattg aaactatggc agcagtatat
    12301 caacggccta tcattatttg ggacaatatt cctgttaatg attatcaaaa agatccagaa
    12361 cgtctctttt taaccccttt tgccaatcgc tcgccatttt tatgccagcc aggctatcag
    12421 gtcaagggga ttgtttctaa ccctatgatt agttgggaat tatctaagct taccttgaca
    12481 gatatgagcc attatctgtg ggatgctaac cgttatcagc ctagtcattc ttggctagaa
    12541 accttaacag actatacaga agatactgaa ttagccttag ctttacaggc atttgcttgg
    12601 cataatggca atcgtcatct gcacagggac cttccttttg aagtggaaga agctctcctg
    12661 gctaaggatg tatcaacgtt atcagcttgg gtagctgaat tggtcgaacg tgtcaatacg
    12721 ttgagaaagc tagataagcc agcgtttcaa caagctattg ctccttggtt tgaacgggtg
    12781 gccaaagacc aagatttttg gcaggctatg ttaaatcagg agcctcagtt ggaaacactc
    12841 tatgctgact tacaagaaga taaacaccgt attggaagtg acattccaag tcgttactat
    12901 cgcatctact atcaacagca agataaacta acagctaatc aaggtcaagt tacccaagca
    12961 agaccggaag actatgctta gcatacgagc tagaaaggaa tgatatgtta gcatttccaa
    13021 aagagttttg gtggggagga gccacctcag gccctcaaag tgaggggcgt tttgctaagc
    13081 agcaccgcaa tctctttgat tattggtatg aagaggagcc tgacttgttt tacgattacg
    13141 tgggacctga tacggcttcg gatgcctatc atcagattga atctgatttg accttgttag
    13201 cttcactagg tcacaattct taccgtacct ccattcagtg gacacgtttg attgatgact
    13261 ttgagcaagc gacgattaat cctgatggcc ttgcctatta taatcgagtg attgatgctt
    13321 gcttggccaa tggtattcgt cctgttatta atttgcatca ttttgacctg ccaattgccc
    13381 tctatcaagc ctatggtggc tgggaatcaa agcatgttgt ggacttattt gtcgccttta
    13441 gcaaggtttg ttttgagcag tttggtgatc gggttaagga ttggtttgtc cacaatgaac
    13501 ctatggtcgt tgtggaaggc tcttatttaa tgcaatttca ttaccctgct atcgtggatg
    13561 ggaaaaaagc agtccaggtc gcctataatc tagccctagc cacagccaag gttattcaag
    13621 cttacaggcg aggtccagca gaacttagtg atgggcgtat tggaaccatt ctcaatctga
    13681 cgccagccta cccagctagt caatcagaag cggatatggc tgctgcgcat tttgcagaac
    13741 tttggaacaa tgacttgttt atggaagctg ctgttcatgg gaaattccca gaagaattgg
    13801 ttgcggtatt gaaaaaagat ggggttttgt ggcaatcaac gccagaagag ttggctctta
    13861 ttgctgagaa tagagtggat tatttgggat tgaattttta ccaccctaag cgcgtgaagg
    13921 ctcctgatgc cattccagtg attagcccat cttggagtcc tgaatggtat tatgatccct
    13981 acctgatgcc tggccgccgc atgaacgtgg ataaggggtg ggagatctat cctgaggctg
    14041 tctatgatat tgccatcaag atgcgagacc attacgacaa tattccttgg ttcttatctg
    14101 aaaatggtgt agggatttca ggagaagacc gttaccgtga tgaaactggt cagattcaag
    14161 atgattatcg catccaattt ttgaaagaac atttaaccta tctccacaaa ggaatagaag
    14221 caggctcgaa ttgttttggt taccatgtat ggacaccaat tgatggctgg tcttggctca
    14281 atgcctacaa aaaccgctat ggccttgtgg aaaataatat ccatacccaa gtgcgacgac
    14341 ctaaagcttc agcttattgg tttaaaaaag tagctactca taaccgcttg atttcattag
    14401 aagtaatgga ggagtttgga ggctctgctt ctcacctcag tgattgaacg tgtgaacgtc
    14461 tcctttgaga caagtgaata atgatgttac caatgattaa acaagggcct ttttcctcat
    14521 gttaagagga tcgaggctct tgtatttctt tggaaagtgt tggtatttgc cgaactagat
    14581 ataagcgttc tgtctggttt agcatcaact acccatcttg tttaatttga ctcttcaatt
    14641 ctttagagta tcttggctaa ggatgcttgt ttttcatctt ggtattttag gattttcttt
    14701 catatttttg ggccagataa aagtccctta tggtttctag tgactgtttg ttatgtcact
    14761 gtccacgata aggggactat atgagtgagt tattaagtga ggctttgctt attggcgata
    14821 actagcatag cttctaatag ctcgagcatt aactgatgac caattccttt aacagaagcg
    14881 tcagcaacaa tgacatcaac aaagggacca ggcatcaggc tgtgttcatc agcagagagt
    14941 catttaggca gaaagccagt atcgttgtag ctaatcagca atccttttag gatgtctttg
    15001 tagatgtcag aggcgattag ggacaatagg ggataagagg gatttagcgg tccatggtta
    15061 ggcctccttg tgttcttggt aaaaatcaat ggcagctccc agaagattag cttcgttttt
    15121 aaagtgacaa atagctaatt ggggtctaag gtcggagatt tcgacggctt ggtagagttt
    15181 gtctagttca gcttcaatcg ctgacagtag aaagtcagct tgggaaacac cacccccgat
    15241 taaaatcagt tgaggatcaa aggcgtgttg aatgttaaaa ataccgatgg ctaaactttg
    15301 gagaaagacc tgcctttctt tgagtgctag gggatctcct tgttctgcga gggcaaggac
    15361 agctttgcca gtataatctt ttccgttatt gacgattgca ctatagcgct tggccatatt
    15421 taccactgtc cctaactgac taaaggtttg gtagcggtcg ttcatgatca tgaaaccaaa
    15481 ctcgccccca aataagtggg caccatggta aatcttgcca tcaatgacca agcttcctcc
    15541 aactccagta ccaagaacga gcatggctag gctactagcg ccttttcctg cccctaaggt
    15601 agcttcagct aaggcggcac aattggcatc attttcgata gaaatagggt aatgtagccg
    15661 ttcttctaag gcctcttgta ttttaaaatg gtgaatgtag ggaatagcgc tggcgccttc
    15721 gataaccccc ttttctttat tgactgcccc aggtgaactg atggcaatac ctgagaaatg
    15781 gtaagcagag taacgagcaa cttcttggtc gagtaattgg taaaactttt ccagactaga
    15841 gggagtggga aagctgcttt gctggcttaa ttggccattg tgacagaggg caaatttaag
    15901 ggaagtgcct cctatatcaa tacataacaa gctcatgagg tgttctcctt tattatagta
    15961 gaatagacga tcatgtctca tcttagtatg acagatttaa gcaacaacga aaaggctttc
    16021 taagtgattc tatactttgt gttatcatac ctataatttg ttgctttcaa ataatgaaag
    16081 cgcttgatat actgtaacta taacgtgatt aacacaaagg gaggttggga aatgataaga
    16141 caaaccaaca aaaagacatc cttttggaaa aatgtgatta aataccgggc cttattatta
    16201 atggtattac caggtttcat ctggttcatc tttttctttt atattccagt tttagccaat
    16261 gtggttgctt ttaaagattt tcattattca gcagggggct ttatggaaag tttgaaggag
    16321 agcccttggg ttggtttggc taacttcaaa tacctctttg cttccaaaga tgcttggttg
    16381 attaccagaa ataccattgc ttacaatgtg attttcttac tctttaatgt tttctttgcg
    16441 attgcttttg ccattatcat gagtgagtta cgaaataaga gaacggttaa ggtctatcac
    16501 accatgtcct tattgcctta tttcttatca tgggtggtta ttgaatactt tgtttctgcc
    16561 tttttaaata cggataaagg tttcattaat cagctcttga ccggaagtgg agcagatcca
    16621 atcaagtggt attccaatcc cacttggtgg cccttgattt tacttttcat gagtgtctgg
    16681 aaggggctag gctacaatag cattatctac tatgcttcag tcaaagggat ttctgatact
    16741 tattatgaag ctgctatggt ggatggtgca agcaaatggc aacaaattag gaacatcacc
    16801 attccacaat tattgccaat gatgtctatc ttattgatca ttaatattgg taatattttt
    16861 aaatctgatt tcggactttt ctacgttatt cctaagaatt caggcccact ttatgacgtg
    16921 accagtgtgt tagataccta tgtctacaat gccttgactg ctacaggaga tattgggatg
    16981 gcatcggcag ctagccttta tcagtcagta gttgggacca gcatcttgtt agtcaccaat
    17041 gcgattgttc gtcgcatgga ccctgatgca gccttgtttt aggaggaaaa catggagaaa
    17101 aagaaaaaag tcgaaaaggt taatgttaga acctttgatc gaaaaaccaa tgctatcttt
    17161 aatattctga ttggtctgtt tgccatctct tgtatcattc cttttatctt cgtgattatt
    17221 atttccttca ctgatgaaag ttacttgatt aatcatgggt atagtttttt tccagatgtc
    17281 tggtcaacta aggcttacca gtatattttt caaggagcca tgtcccatag aatcatgagg
    17341 tcatttggga tatccgtgtt tattacagtg gtgggaacct ttattaacac gaccatgaca
    17401 tcaacctatg cttatgcgat ttcaagacct tatttcccat acagacgttt ttttactgtt
    17461 tatgcactta tcaccatgct ctttgcacca gggatggttg ctaattactt ggtggtcagc
    17521 aatctccttc atttgaagga tacggtttgg gccttgattt taccaatggc tctgggccca
    17581 tttggcatct tggtcatgag aacgttcttt aaaaagacag ttccagatag cattattgag
    17641 tcggctcgta tggatggggc tagtgaatgg atgattttta tgaaaattgt cttaccatta
    17701 gctgttccag ggattgccac catcagttta ttttctgcct taacttattg gaatgattgg
    17761 tttaacgcct tgctttatgt gcaaagtgag aatctttacc caatgcagta cttactgatg
    17821 aaaattcaga gcaacctaca ggccttggca caaaatgctg gcatgagtgc acaaatggca
    17881 gatagcttag catcgctgcc aaaagaatca gttcgtatgg ctatcgtggt tattgcaacc
    17941 ttgccgattg ccttgactta cccattcttc caaaagtact ttgtcggtgg tttgaccatt
    18001 ggtggggtga aggaatagga cttaaggaac tggtcacaag accagatttt atctaatcat
    18061 tagtaacaaa agaaaacatt ttttaggagg cttcacttat gaaaaagtgg caaaaaatcg
    18121 tgtgtgtgac tggaactgtg cttgcagcgt ctagtttagc agcctgcgaa agcaagtcag
    18181 catcaaagga tagtgatgtc aaattattga tgtaccaagt tggtgacaaa cctgataact
    18241 tcgatgaatt gatgacaatt gctaacaagc gcatcaaaga aaaaacaggt gcaacggttg
    18301 accttcaata catcggttgg ggggactggg atgataaaat gagtaccatc attgcctctg
    18361 gtgaaaacta cgacattgct tttgccaata attatgtggt caatgcacaa aaaggtgctt
    18421 ttgctgattt gacaacgtta atgccaaaat acgctaagaa aacgtataaa aacttagacc
    18481 cagcctatat taaaggaaat actattgacg gtaaactcta tgccttccca gtagatgcca
    18541 acgtttatgc ccaacagatg ctttctttca ataaagaact agtggacaaa tatggccttg
    18601 acatttcaaa cattaagtcc tatgcagatg ctgaaaatgt cttgaaacaa ttccacgaaa
    18661 aagaaccaaa tacagcagct tttgctattg gtcaagtctt tagtatgtca ggtgactatg
    18721 actacccatt aaccaaaacc caaccctttg ctgtgaaaat tgatgaaggc aagccaacca
    18781 tcattaatca gtatgaagat gagtccttta aaaacaatct ccgcttgatg cacaaatggt
    18841 ataaagaagg tttgattcca acagatgcag cgaccaatac agaaggttat ccccttgaag
    18901 gaaacacttg gtttatgcgt gaagaaaccc aaggtcctat ggactatggc gatactatct
    18961 tgaccaatgc tgcaggaaaa gacatcgtgt ctcgtccatt gactaaaccg ctaaaaacca
    19021 catcacaagc acaaatggca aactttgtgg tatcaagcgt atctaaaaac aaagaaaaag
    19081 cagttgaagt cctttctctt cttaatagcg atcccgaatt gttaaatggg cttgtttatg
    19141 gtgtcgaagg caaagcttgg gaaaaaattg gcgacaagaa aatcaaactg ctcgatggct
    19201 atcaaccaaa aatgcacatg ggtgcttgga atactggtaa caataaaatc ctttacactc
    19261 aagaatctgt tactgacgac atgattgcta aacgtgacca atcaatcaag gatgctaaag
    19321 aatctccaat ccttggtttc actgttgaca caaaagttat caaaacggaa ttgtcaaata
    19381 tttcaaatgt catgaaccga tataaagcaa gtatcaatac tggtacagtg gatcctgacg
    19441 aagcccttcc aaaacttctt gcagacctca aaggtgctgg ttgggacaag gtgcaaaaag
    19501 aagttcaaaa acaattggac gactttgtag ctaaagacaa gtaaggcatt cattttcttg
    19561 attataagtt gagggctggg aaatctcagc tcttttcttc tgatgagtgg aaaaaacgga
    19621 tcatcaaata agtggaagtt ataaagggag aaaaattaat gtcaataatg ttactactct
    19681 tagtaaagcg gtttccaaaa gcctataaag tgtgctatat tagaagagtc taaactatta
    19741 atcagagtaa aactaatacc agcatcttac tgggggtgct aaaactagtc tcgtagctgc
    19801 tggtccctga aactgctata agtgttaaca agaaaaagag gactatcata tgaatggcat
    19861 tgaaaaaacc tgctttttaa tttggaaaat gatccaattg accctcattt ttcatctctt
    19921 gtccttagct ggactgattg tgtttggggt ggggccagcc tggcaaacca ttgtcaccct
    19981 atttttaaaa acacctcaag aagaaaacca ctattctttg aaaagggctg ttcaactttg
    20041 gaaatcttat ttcaaagaag ctaatctaag atttggtctt tttgccctga ctttcctttt
    20101 tttaaccttt aatttgcatt gggcagtaca gtttccatcc ttgttttggt ttaccgtgtc
    20161 tttcttgatt gtaatagcca tggtttggct aaccatgacc tatctttaca tggtttttta
    20221 tgcagtgagc tatgagatta acctttggaa taatatgaaa ttagccttta tcagcgtctt
    20281 tttaagtttc aaatcctttt tactcatgct gagtgttttg ttgggaatta ccttagtgac
    20341 ttggcaatac aaaggtcttt atctcttttt aaccttcgga gctctagtct tttgcttgga
    20401 ctttgtcact aaggctaatc gtcgactagt agatggagtg attgatgagt gttaaaacat
    20461 tgggaaggta tgtgactaac cactttaagc agggtttttt gattaatcga ctgatgaaat
    20521 tatatagcct gctaattgta agttttttca ctttagcagc tattggcttg agcagttatt
    20581 ctattagtag tacttataaa agggtggatg ctgaggcgca gatgcgattg gaggagactc
    20641 taggtagatt gcagtcacaa aacgatatta ccctacgggt tttagaccag ttggttggcc
    20701 gttcagaaga ttaccataat ctctatcaat acatgacgtt aaccccaaac caatattttt
    20761 caaacgtttt tgaagactgg gaaaaaggaa aagacacggt cctattttct gaagaggtga
    20821 ggcgtctttt tgacttgtac cctgatgtga cttctatgac cctactgcta gaggacagta
    20881 gtgcttatct gtacgccgat aaggtcatta agacgggtcg tttgctttat agcaagcctg
    20941 aaaaagtaac cggaaatgtt ttagttcgct ctattcgaaa tccagaatca ggagatgtga
    21001 caggtcgtct ttacctgacc tttgacaaac caccgacttt ggtagagaca cagcaggatc
    21061 actatttagc tacttttgct tttgattact atggccgcaa actcttccat caaggaggtc
    21121 ggagatttcc tcatttagag gctgaggtta aaaaggctat caaggcagat cgggcagctg
    21181 atcttagtaa tcttagcaag gcttatcgga tgcagtacaa tcgctcggga gacctcttgg
    21241 cttatgtggc tgtcagaaaa tcctatttat tagcggaagc tgtcaggaca gtttttgtgt
    21301 atggccttgt ttctctactt ttagcttggc tgttattgca gttgctcttt agggttttcc
    21361 gaaattatat ccagcaggtt tctgaaatta cggatactgt tgaaatggtt gcagcaggcg
    21421 atttgtcttt aaccatcgac aacagccaca tggaattgga actgtatcat atctcagaag
    21481 ccattaatca gatgttggcc agcattaaag cttatattga cgaagtttat gtgttagagg
    21541 tagagcaacg agatgcccaa atgagagctc tgcagtctca aatcaaccct cattttttat
    21601 acaacacgtt agagtatatt cggatgtacg cccttagttg tcaacaagaa gaattagcag
    21661 atgtcattta tgcctttgcg agtctgcttc gcaacaatat tagccaagat aagatgacca
    21721 ccttaaaaga agaactggct ttttgtgaaa agtacattta cctttatcaa atgcggtatc
    21781 cagatagctt cgcttatcat gtaaaaattg atgagagtgt tgctgactta gccattccta
    21841 aatttgtcat tcaacctctc gttgaaaatt attttgtgca tgggattgat tatagtcgcc
    21901 atgacaatgc actaagcatc aaggctttag atgagacgga ttatctcttg attcaggtgc
    21961 ttgataatgg acgtggtatt agtcaagagc gcttagcaga tatggaaaaa aggcttcaag
    22021 agcaccaaac aacaggcaat agctctattg gtttgcaaaa tgtttacctc cgtctctttc
    22081 atcattttcg agacagggtt tcttggtcca tggctaagga gccaaatggt ggctttatca
    22141 ttcaaattag gattagaaag gatgcttgat gtataaggta ctattagttg acgatgaata
    22201 catgatttta caagggctca ccatgattat tgattggcag gcacttggat ttgaagtggt
    22261 tcaaacagca agatcaggca aggaagcctt agcctatttg actcagtacc cagtggatgt
    22321 catgatttca gatgttacca tgcctggaat gacaggactg gatttaatag aagcagctaa
    22381 aacctatcat cctcagctac aaaccttgat tttatctggt tatcaagaat tctcctatgt
    22441 gcaaaaggct atggaattag aaaccaaggg gtatttgtta aaacctgttg ataaggcaga
    22501 attacaggct aaaatgaaac aatttaaaga ctggttggat gcccagcagg cagaatcaat
    22561 ccggcaagaa gcctatcatg acagcctttt gaccctttgg cttacagatg aattgagtga
    22621 gaaagaattt cagcagttaa gtcaaggctt gccagcggct gctttaactg gttttacagt
    22681 gctgtatttg gactgtcaag agtggcaagc agccatcgat gcttattttg aacgagaagg
    22741 tcagcctttt tatctcaaaa aagaagaaga taagaaggtt tatctggctg tcctacttgg
    22801 taaaactgat caagccaagg cgtttaccta tgatctacaa aagcgattct caagaaacat
    22861 gcatcaactt attttgggag aaacagttga tgactgggaa aatgtttatg aaagctacaa
    22921 tcaggtgctt aagagcctct tttacaattg tgaagtgtca ccaattagag caaaagataa
    22981 gtccaaaatt gaactaccag agtcccgttt gcagttcttt gcttttaaca aggcgttgat
    23041 gattggggac gaacctacaa tcttgtctaa attagaagct atttttgacg agatgaagac
    23101 cttgaacttt tcaccagagg atgtgaagca tgtttcgttc ttgttgtttt ctgacattta
    23161 tcgtcaattt cccattttag ataaaatgac ttatctgtcc atggtaaaaa ctattcatga
    23221 cagccaatcc attgattgca ttttgaggga actaaaaaaa gtgttggatg tcaccaatca
    23281 gaacaattcc cctgaaaaac gctattcaga tttagttagt gaaaccattg attgcattcg
    23341 caaggaatac catcaagaat taactcttaa agctatcgct gataggttac atgtcaatgg
    23401 ggtttattta gggcaatgct ttaaaaatga aaccgagcgt agttttaccc agtacttaaa
    23461 tcatgttagg attcaaaaag cgcaacagtt attgctttac accaaccaat ccatcaatga
    23521 aattgcttat gaaacaggtt acaataccaa tcattatttt atcaagatgt ttaaaaagtt
    23581 gaatggttta tcgccaaaag agttcagaga tcgttacaag gacaattacc aagccatcaa
    23641 gggcgaccag taacgtcaaa caggagattg atatgacacc agatagcaag gagcagacag
    23701 tgactggcta ccaataccac tatattgatc aagaaggaag aaagcagccc tttaatcaag
    23761 gctggcgttt tcttatggca gatgtggcgt gtgctcagga cccttctttt gatgattcga
    23821 actggcaggt gattcattta ccacatgatt tcagtcttac gcagccttac acaagaaatg
    23881 gtgaagctga aagtgcttat aaattaggtg gtgtcggttg gtatcggcat tatctcgtgt
    23941 tagatgaggt tttagctggt tgtcatgttg ccattacttt tgagggttcc tatatggaaa
    24001 cggaaattta tgttaacggg caattcattg gcaaacactt aaatggctat caggaattta
    24061 cttatgatat ctctgatgtt gtgacttttg gagctgaaaa tcttctggct gtccgggttg
    24121 aaaacaaggt tcccagttct cgttggtatt caggcagtgg tctttatcgt gaagtgagtt
    24181 tgtctgttct tccccagctt cattttgtgg cagaccaggt agcaatgacc ttggctgata
    24241 ctgctgtgca ggagaaaggg caacagaaag ttgatttacg ctttgccctc aatcagtcta
    24301 ttcagacttg ccactaccaa ttgagcctct gtttatggga acaatcacat tgctcaaaag
    24361 acaagaaact cctttatcaa gaaacagaag tgcctctagc tgatttggct ttccaaagac
    24421 agtatggtct tacactgtct ttggaagaac tccaattgtg gtcaccagat aatcctcacc
    24481 tctacgattt agaactcact ctttactatc aaggtcaggt cattgattgc ttttgccttg
    24541 aaactggttt tcgtcagctg acttttatgg ccaatcaggg gctttttgtg aatggcagag
    24601 ctgtcaaatt aaagggagtt tgtttgcatc atgaccaagg aggcctagga gcttgtgctt
    24661 acgaagatgc cctagccaga caattagtcc tgttgaaaga catgggggct aataccattc
    24721 gtagcaccca taacccaagt agtcccaaac ttaggcaact agccaatcgt ctcggctttt
    24781 ttgtgattga agaagccttt gacacctgga cctatgccaa aaatggaaac gttaatgact
    24841 tttcaaacta tttccatcag actatcggaa ctgaaaatgc aaactatctt caaagagtga
    24901 ggtcacctga aacgagctgg gcccagtata gtattgaggc catggtctgg tctgccaaga
    24961 atgacccgtc agtgttgatg tggtcgattg gtaatgaatt gatggagggt ttttcagccg
    25021 atgtcagtca ttacccagag ctgacaagac aaatgtgcca atggattact gctattgaca
    25081 cctcacgtcc cattaccttt ggggacaata aattaaaaga agctgacttt tgctggcatg
    25141 aggaagtgtc gcaaatggca actcttctta gtcaattaga ccatcctcag ggactcattg
    25201 ggttaaacta tgctgatgga aaagactatg ataggcttca tgaggagcac tctgattggc
    25261 tgttgtatgg ttctgaaaca gtctcagcca ttaccagcag ggcttattat aaagagacaa
    25321 aaaaagttct tgactccggt tatcacctaa cctcttatga tcatgctaag gttgattggg
    25381 gtgccttcgc tagccaggct tggtatgata ccattacccg tgattttgtt gctggcgaat
    25441 gcgtttggac aggctttgat tatttaggag aacctacccc ctggaacaag atcgacagcg
    25501 gtgttgtagg cctttggcct tctcctaaaa atgcctactt tggcatttta gacacggcag
    25561 gctttccaaa agatagctat tatttttacc aaagtcagtg ggcgcagggg cagaccacct
    25621 tgcacctgtt accagtctgg cagaaggacc agctttgttt cgatgagcag ggattggtgg
    25681 aggttgtggt ttatagcaat gctgccagtg tgcaactgat gtttgaagat gagcagggca
    25741 acttaacaga ttatggaagg aaggcatttc atacttatag cacgccaacg ggacacactt
    25801 atcagcttta ccaaggagct gacgctgcta agaatcctca cgagaacctt tacctgactt
    25861 ggcgagtgcc ctatcaaaaa gggttgctaa gggcagtggc ctacgacatt tctggtaaaa
    25921 gcattccaaa aaccagtgga cgttctcagg ttagaaccta tggttcagtg gcaaagctat
    25981 cttggaaagc ctttgaagca cctattgacg ctccttggga attgctttat ctggatttat
    26041 cactcttgga tagccgaggt gaattggtca gccatgctca agattggttg caggttcaag
    26101 tagaaggacc agcccgtttg ttggctcttg ataatgggaa tccgactgac cacacccctt
    26161 atcaggagcc tctgcgccag gcatatgggg gaaaattatt agccatttta gccctcactg
    26221 gagaggcggg acacattaag gtcacggcaa aagcctcgca gcaacttagc agtgtttttc
    26281 agacacaagt agcctgccgt gcccccaaag aacacttagt gacactacct ttagagaaat
    26341 atcagtttaa aaagagccga ctgacaagtc aacaagaaat tggtcaatct tgtctaaaga
    26401 ccacacaatt cctttctgtt ttggagaaca aagacaccca gcaaaaagca ggtaaggcta
    26461 gcacacctca cattcttatc actagttacc agcactattt atctctgccc ttgcaggttt
    26521 gttctcaggc atttgatttt aaaaaaggcg acgatatctt cttgcctcag tggctccaag
    26581 tcaaagatgc ccaaggttct cttgtgaaaa aagctttttc aatgacgtgg tacctaaaag
    26641 agaaaatctt tgccaagcct attcttgtca caggctatgt ttcttgtttt gggcaatcaa
    26701 taccggttga ggcaaggctt aacctagcac aagctagcaa aagacggcac caggatctca
    26761 gtttagtcgc caagcaatcc ctggccgcaa gtcaaaaaag gctaacttat tgctaccaat
    26821 atgatacggt gcaagccata ggagccatta gcttgcaaaa tcacacaggc acatctctta
    26881 gtgtttctgt ggcaatcagt tatggtagtc agagctctat taagcaagaa accttgatgc
    26941 tagctgatag ccacttgagc cagttagaag aggttatttt cttcgatgat attttgactg
    27001 ttttgtatct ggcagtgacc cttgaagtca ttgaaggacc tgacctaact gaagacagta
    27061 ttcaaattgg cctttgggat ttagcatgaa gcatgagtaa aagaagactt ctttggcacc
    27121 aggtctgatg aattctgtaa aataaggtat aataaaaaac aaataggcgt cctttattac
    27181 gtgaaaggcg cctttacaag gttgaaatgg aaagtgagat ttctaaatgt cagaacgttt
    27241 atcaggccac accctgttgg tctctttgct tgctacccct attcgtcata gtttgtctcc
    27301 caaaatgcac aatgaagcct atgctaaact ggggctggat tatgcctacc ttgcttttga
    27361 agtagggaca gagcaattag cagatgccgt gcaagggatt cgtgccttag gaattcgtgg
    27421 ctccaatgtg tctatgccaa ataaagaagc tattttaccc ttattggatg acttgtcccc
    27481 agctgctgag ttggtcggtg cagtcaatac ggttgtcaat aaggatggta aaggacatct
    27541 cgtggggcat attacagacg gtataggagc gctcagagcc ttggctgacg aaggagtgtc
    27601 ggtaaagaac aaaatcatta ccctagcagg agttggtggg gctgggaaag ctatcgctgt
    27661 ccagctcgct tttgacggcg ccaaagaggt tcgtttgttt aaccgacaag ctacacgtct
    27721 aagtagcgtt caaaagcttg tgacaaaact gaaccagcta acaaggacta aagtaaccct
    27781 tcaagacttg gaagatcaga ctgcctttaa ggaggccatc agggaatctc atctatttat
    27841 tgatgctaca agtgtaggaa tgaagccttt agaaaatcta agtttgatta ccgaccccga
    27901 gctcattcgc ccagacttgg tggtctttga catcgtgtac agcccagcag aaaccaagtt
    27961 actagccttt gcccgtcaac atggcgccca aaaagtcatt aatgggctag gaatggtgct
    28021 ttatcaagga gcagaagctt ttaaattaat cactggtcaa gacatgccag ttgacgctat
    28081 taaacctctt ttaggtgatg agtaacactt tttaagtaag cttaattatg atatattaat
    28141 aagagatgga gcagtcatca tgggctgcta aaattctttt tgcgagagct gtttttaaga
    28201 gcaaaaagct tatttgaaga gccttatccc taacgtgata caagtcatag ttcctttgag
    28261 gtctgccaga taacctaccg tttttttaga aaagaagctc ttataaaagg aaaagttcaa
    28321 tgaataaagg agaatagcaa tggtaacaaa ggaagttggg catgactttt tagcacgtct
    28381 aggaaaaaaa cgcttaagac ctggcggtgt tgaggcgaca aactggttga ttgaacaagg
    28441 acaattctct caggattgtc acgttttaga ggttgcctgc aatcgctgca cgacagcaat
    28501 agagttagct aaaaccttcg gttgtcagat tgatgccgtt gacttaaacc ccaaggttgt
    28561 caaagaagca caagaaaggg ttgctgttga ggggttaacc cgtcacatta cagtatccca
    28621 agccagtgct ttatcactac catttccaga taaccatttt gatattgtga ttaatgaagc
    28681 catgttaacc atgttgaacg cccaagccaa ggagaaggca ctcaatgaat attggcgtgt
    28741 gttaaaacca ggcgggcgac ttttgacaca tgacgtagct tatgaagatc caaaaacaag
    28801 acaagtactt gacgagttac gtcaaacgat tcatgtcaat gttgctccct tgtcactaac
    28861 aggttggcaa gccttatatc aagaacacgg tttttctcaa gtgacttatc accatgggaa
    28921 aatgtctttg atgacacctc gtggaatgat taaggatgaa ggtcttatga acaccctgaa
    28981 cattatgaga cgaggcctta agaaagagaa cagacaacag tttttaaaga tgcgtcgttt
    29041 ttttaccaga acaggcaaaa atctctgcta tattgctgta aaaagtgtaa aataaacctt
    29101 agaccaacct gtccatacaa ctaaacagac catagaggag ttcgaagatg tcttatatca
    29161 ataatattga gcacgcgaag gttcttgatt tgacgcaaga agtaatgatt gagcaagatc
    29221 aaatgttaag tagaacacta gtccaaaggc aagacctagg aataacagtt ttttccttag
    29281 ataagggcca agaaattggg cgacactcat caccaggaga tgccatggtt actatcttaa
    29341 gtggcttagc agaaatcacc attgatcaag agacctaccg ggttgctgaa ggtcaaacca
    29401 ttgtgatgcc agctgggatt cctcatgcct tatatgcagt agaagccttt caaatgcttt
    29461 tagtagtagt aaaaccggag gcttaacatg attgaaaatc tctctcaatt ggtgcaatat
    29521 catgatcatc aggtggctag ccgatccttg agccgtctac tgggattatc tcaatctatt
    29581 gttttatatg ccatggccca aggagaaagc attagtcaag agactagtcc aagagataaa
    29641 gtaatacttg ttttagaagg tcagctcatt ttcgatttag aggatcaaaa acaggtccta
    29701 actcaagaaa gtctcatagc catacctgcc caaaaagtcc atcatttaga agctaaaacc
    29761 gattgtaaac tattacaagt gcttttagat taagggctta ttgtcaactg tattgggtgg
    29821 cctatggaaa agcaaaagag aaggtgacgc tcatcttctc tttttacgta ttcaaagcga
    29881 tgacaatacg aattttaaag cttggctttc tcatctccag attaagccct ttagcttggt
    29941 ttattttaga attcactaaa aaaaccttaa tgagtttcct atctccttat aggtttctca
    30001 ttaaggcttt ttagacgaaa taattgaacg acaggcaaaa gaaagatctt tttacgagtg
    30061 ataccgttct cctatagttc cataaatcct ctttttgatg ttgctgttag ttattcttag
    30121 ctaaaagtta tattgttatc aagacttgtc tgtagtaaca tgttttagga gttccaggat
    30181 accgttattc tcttagcaag cttaactagc tagagtggag tcactattta taataaactg
    30241 tcgagcttct cgacaaattg gtgatcgtct ttgttaatgg ctagggtggt aaaaccggtt
    30301 tctgtgggta atataaagat aatatgttgc tcagaattct tcttatctgt tttaaagacg
    30361 tcaaagaggg atgtcgcaga gacatcagct ctttcaagtg ttgttggtaa ctggtaacgt
    30421 tcaaaaactt gaaggaggct atccaagtcc tcttttggca agagtccttt ggaaacagcc
    30481 agtttagcat caaccaccat accgatagca atggcttcac cgtgatggta aaaatcatgg
    30541 tggcagagcg attcaatcgc gtggcccaag gtatgcccaa aatttaaaga catgcgcaaa
    30601 ccattttcaa attcatcttg ttcaacaatc cgttttttat tggaaatgga ttggtaaatc
    30661 agacgttcaa gtccctgctt atcggtttct ttttgaaaat cacgtaactg ctgaaaaagc
    30721 ggtctatcat gaatgaagcc gattttgagc atctcactga tgccgcagga gaattcccgt
    30781 tgcggtaagg tctccaaaaa ggtggttgaa ataatgatag cttctggagg gtaaatgctg
    30841 ccaatcatat tggttagacc tttaaaatgg actccaactt tgcccccgat actgctatcc
    30901 acctgactaa gtaaagtcgt tgggatttga atgtagggaa taccacggta ataggttgca
    30961 gcgacaaaac cacccagatc cccaacaaca ccaccaccaa tagtaacaat catatctttt
    31021 ttggaaaaat tttcagcgat gagctggtcg tagatagcac tgacacgttc caaggatttg
    31081 gattgacctc ccggagggca gacatggaca aaagcgttgt attgctgagc aaattcttca
    31141 aagagagtct gatacaagtg gtagaccgtt tgatcggtga taaacaagag tttacgctgc
    31201 ttgcgctcac caaggcaatc tgctaaggtt tttaaaacat ggtcggtaaa caggatatca
    31261 taatccttga cccgagaatg gacatgaagt gtttgtggca taagcactcc tttcatcagt
    31321 actaggtaac agagataacg cagtgatatt tagagcttaa tcttgccaaa gttcctgccc
    31381 caactgttct aattgcttat aatcaatttg ctgggcagca tctgacagcg catggtcggg
    31441 atcaggatga acctccatca tgatgccatt ggcaccgaca gccttcgcta tcttagcagc
    31501 aggtaagagt aaatctcgtc tgcctgtcga atgagatacg tccacaataa tcggtaaatc
    31561 tgtcttttgt tgaataatag ggactgccat aatatcaagc atatttctag tctccacatc
    31621 gtagccacga acgccacgtt cgcataagat aatgttagat tttccagtgt cttgtaagta
    31681 ggaaagggcg cccaaatatt cctcgatagt agccatcaag cctcgtttaa acaaaatagg
    31741 cttatcgatg tgtgacaagg tttttaaaaa ttcaaaattt tgcatgttgc gggcaccaac
    31801 ctgaatgaca tcgagatagt cataggcttc ttctaattgg cgctcggaca tgatttcact
    31861 gaccgatagt aagccaaatt cctgacaaac ctcatgcaag taacgaattc cttgcaggcc
    31921 aaggccttga aaagaagcag cagatgttct tggtttatag gcgcctcctc taaaatagtt
    31981 gtaaccaagt tttttggcac ttgaagctgc taatctaatg tgatcataag attcaatgga
    32041 acaaggtcca acaataaaat tattcttaga acaagtctta ttttgaaagt cagacataat
    32101 gtcaatcatt cgtttgattc ctttactaat tctgtatggc gtgctctatg ggataacgtc
    32161 ttatttagga atacaaaatc tcgttgttat ccatgaagca cccttagcct gtgaaatgat
    32221 accataaaca agatgaaata gcaagtaaac cctagattgt ctatgttctt agtcattttt
    32281 attaaaaaag gcttactagc tataaaaaaa tactgcccta aatcttatta ggacagtatt
    32341 tttttataga tgccaccacc gagaatcgaa ctcggaacga agcattacca ttgctttatt
    32401 ataccattta actacagcgg ctaccttttt ataatactat aagttattaa ttgatgcaag
    32461 cttttcttaa aaatatttcc ttaattgttt atcatcaaaa tgagggtacc agttattaat
    32521 aacatggcac aagaggcctg ccttatggta taatggtaaa gataatttca gaaagaggaa
    32581 gccaagcatg tcttatgaaa aagaattttt aaaagatttt gaagactggg ttaaaactca
    32641 gattcaagtc aatcagctag ccatggcaac cagtcaagaa gttgcccaag aagatggcga
    32701 tgaaagggct aaagatgcct ttattcgtta tgaaagtaag ttagacgcct acgaattttt
    32761 actaggtaaa tttgacaatt ataaaaatgg taaagccttt cacgatattc cagatgagtt
    32821 atttggagca aggcattatt aagaaggaga cacgaaatag tggcaaaaca aaaaaatcgt
    32881 aaaaaagcat tgaaattaga aatgaagcgt aatggcttgt taaaaaaagc aggtcaagtt
    32941 tttgataagg cagttgaaag tgttgaaaca gctgtggata aaaccatttc tgctggtaaa
    33001 aatcttgtgg aaaaaggcag ccaaacagtt gaaaacctga cagcaagcaa ggaaagactt
    33061 actcttgatg agtttgcagg gcagccagtt gtagctggta tccgctctga ccttgtcgaa
    33121 accctatatg cagaaggcat ccattcagcg caagctttta aggagtggac agaaaaagac
    33181 ctccttgctc ttaagggcat tggtccagca acggttaaaa aattggtcga aaatggtgca
    33241 agctttaaaa aatagtcatc ttctcgttgc ttaatggcta taaatttgtt agaatattag
    33301 caatcagagg tgcattgagt tggtctgtta cagagagcgg tggtgttgag aaatccgcac
    33361 agatgtcaag gctagtagct gaggatcaga aatcagatat gaaaagtagc agacccattt
    33421 tatggtctga aacagtggtg gtaccgcgga aatcgtaaca cgaaattcgt ccctgtctag
    33481 gttatctagg cagggattat ttggtttcat ttgaaagaag atgatggctt attgttaaaa
    33541 ggttgttaga agtatataat agaaaaactt tgcccaaagt ggaaacagaa cggctgctat
    33601 tacgtcaacg aaaaggggac aaggcattgt tccagaagcg gcttcagctc tgattgaaat
    33661 tggttttacc ttacttgatt tgcataaaat tgagctgggt tgctacgact acaacaagca
    33721 aagtcaggca gtggctcgca aattaggctt taccttagaa gccaatgccc gtgaccgtaa
    33781 ggacgttcaa ggtcgccgct gtggcgacat gcgttttggg ttactgagaa gtgagtggga
    33841 ggagcagaaa caaaaatgaa ccttatcatc attggtgctc aagcgtcggg caagatgacc
    33901 attgggcaag aagttgccag gcagacaggc atgactttgt ttcataatca cgattctatt
    33961 gactttgttt tacggtttat gccttggtct caagagagca ctgccttgat tgaacgtatc
    34021 cgttttgctt tttttgaaac ctttgctaag acaggtcaag acatgatttt tactattgta
    34081 attgacttca atgatccaaa tgatgtagca atgcttgaaa agattcaggc tgtttttcag
    34141 tcttatgacc aagaggttct ctttgtcgaa ttaaaaacag atatagagga acgtcttaaa
    34201 cgcaatcgca cagaaaatcg tctcaaacat aaacctctta aacgcaacat cgagtggtca
    34261 gaacaagata ttcaatccac gatggcatat gctgttttta atccagaaga accacccaaa
    34321 acgctcacgc attaccaaaa aatcaataat acccagctca ccgctgctga aacagcgcag
    34381 cttattatcc aaaaaatgac tcatatcaag gagaactaag atgacagaac tatcacctaa
    34441 atacaatcct gccgaggttg aggcaggtcg ctatcaaaaa tggcttgatg cagatgtttt
    34501 caagccatca ggagaccaaa aagcaaaacc gtattctatc gtgattccac cgccaaatgt
    34561 gactggtaag ttgcacttgg gacatgcttg ggacacaaca cttcaagata ttatcattcg
    34621 tcaaaaacgc atgcagggct ttgatacgct ttggcttcca gggatggacc atgcaggaat
    34681 tgcgacacag gctaaggtag aggagcgtct gcgcgagcag gggatttctc gttacgacct
    34741 tggtcgtgac aaattcctag acaaggtctg ggagtggaaa gacgaatatg ccactacgat
    34801 taaagagcag tggggcaaaa tggggctttc tgtggactac agccgtgagc gcttcaccct
    34861 tgatgagggc ttgtcaaaag cagttcgcaa ggtttttgtt gacctctaca aaaaaggctg
    34921 gatttaccgt ggtgaattca tcatcaactg ggatcctgct gccagaactg ccctttctga
    34981 catcgaggtt atccacaagg atgttgaggg agctttctat cacatgaact atatgttgga
    35041 agatggctca cgcgcccttc aagtggcaac aacgcgacca gaaaccatgt ttggagacgt
    35101 tgccgttgcc gtaaacccag aagatcctcg ttacaaagat ttgattggca aaaatgttat
    35161 tttaccaatc gtgaataaat tgattccaat cgtgggtgac gagcatgctg accctgaatt
    35221 tgggactgga gttgtgaaaa tcacgcctgc ccatgatcct aacgatttcg aggttggtca
    35281 acgccataat ctaccacaag tgaatgtcat gaacgatgac ggtaccatga atgagttagc
    35341 tggcgacttt gcaggcatgg accgttttga agctcgtcaa gctaccgttg ctaaacttga
    35401 agaacttggc gccctagtaa acatcgaaaa acgtgttcac tcagtaggtc actcagaacg
    35461 ttcaggtgca gtcgttgagc ctcgtctatc cactcaatgg tttgtaaaaa tggatgagct
    35521 tgctaaacaa gctatggaca accaagaaac agatgaccga gtagatttct acccaccacg
    35581 tttcaacgat accttcctcc aatggatgga aaatgtccat gactgggtaa tctctcgcca
    35641 attatggtgg ggtcaccaaa ttcctgcttg gtacaatgca gaaggtgaga tttacgttgg
    35701 cgaagaagca ccagaaggtg atgactggac tcaagatgaa gatgttcttg acacttggtt
    35761 ctcatctgct ttatggccgt tctcaactat ggggtggcct gacacagatg tagaagattt
    35821 caaacgttat ttcccaacct caaccttagt aacaggttat gacatcattt tcttctgggt
    35881 gtcacgtatg attttccaat cgcttgaatt taccgggcgt cagccattcc aaaatgtcct
    35941 gattcacggt cttattcgtg acgaagaagg acgcaaaatg tctaaatcat tggggaacgg
    36001 gattgatccg atggatgtca ttgagaaata tggtgccgat agcttacgtt ggttcctctc
    36061 aaacggctct gccccaggac aagacgtgcg tttctcatac gaaaaaatgg acgcctcttg
    36121 gaatttcatt aataaaattt ggaatatttc tcgctatatc ctcatgaata atgaagggtt
    36181 gacattggaa gatgctgaaa gtaatgtggc taaggtagct gcctcagaag ctggaaatgt
    36241 gactgaccag tggattctcc acaatctcaa tgaaaccatc gctaaagtga cagaaaactt
    36301 tgacaagttt gagtttggtg tggcaggaca cattctttac aactttattt gggaagaatt
    36361 tgccaactgg tatgtggaat tgaccaagga agtgctgtat agcgacaacg aagctgaaaa
    36421 agttatcacg cgctctgtcc ttctttatac tttggacaag attttacgtc tccttcaccc
    36481 aatcatgcca tttgtaacag aagaaattta cgctcaatat gcccaaggtt ctattgtgac
    36541 ggtggactat cctgtggttc gcccagcttt tgaaaatgaa gctgcgcata aaggtgtgga
    36601 aagtttgaaa gacctgattc gtgcagttcg taatgcgcgc gctgaagtta acgtggcacc
    36661 atcaaaacca atcaccattt tggtgaagac agcagatagt gaattagaag actttttcaa
    36721 cagcaatatc aactacatca aatgcttcac taaccctgaa aaattagaaa tcagctcagc
    36781 cattgctgcg ccagaactgg ctatgaccag catcatcaca ggtgctgaaa tctacttgcc
    36841 actagcagat ttgcttaacg tggaagaaga acttgctcgc ctagataaag aactggctaa
    36901 atggcaaaaa gaactggaca tggtcggcaa aaaactcggc aacgaacgct ttgttgccaa
    36961 cgccaaacca gaagttgtcc aaaaagaaaa agacaaacaa gctgactacc aagctaagta
    37021 cgacgcaacc caagaacgga ttgcagagat gaagaaaatt aaatcatagt gtttagaacg
    37081 cagttgaaaa actgtgttct tttcttacta atagagatat tagattgaag tttaattatg
    37141 agaaaaacgc tttctttatt taaagagtta tgttacaata ctattacaat catcgtacaa
    37201 atagtgttat tttgagaggc atatgagaat gattttagca cactatgact gtaaaaaaga
    37261 taaaaagcaa tctttagatg agcatttatg gcatgtggcc tgttctagtc gacaggaagc
    37321 atctataatt ggtcaaggag atgtgctttt tttaattggt ctttaccacg acctgggcaa
    37381 agctgatcga acctttcaag ataaattatt aaataatcca aatcggcatg ttgatcactc
    37441 ttatgcaggg gcaaaatact tatgttctat tattgggcct catctaaaaa accgaggggt
    37501 tgataaaaat gagagaatga cattcaacga aatggtgggg tatgtcatct ctgctcatca
    37561 tgggatgtat gatttatgct actattttga cgatgctgaa tattatggct ttaataagtt
    37621 taaaaatcgt atcaatagag acttagatgg ttatcactat catgaagata ttaaagggta
    37681 cgctctaaaa ttagaaaaaa aattatgtga ttatggctac aaagatttaa gggagcttat
    37741 tgataaagct tttgataatt accaacaagc catgtcttcc ttaaactggc aagataagag
    37801 tgagtgggat tattatcagt cttgtatggt gagactttac ttgtcactct taaaaaacgc
    37861 tgatattttg gacacagtaa atgcctatgg ccttaagata agtcctatgg ataaaacaga
    37921 gcgatccttt ctaaaacact cctatttagc ggccattgaa caaaaatatg ctagctttgg
    37981 acagccaaac aatcagttga acactattcg gacagaaatc gctgagcgtg ttaaagaaag
    38041 aggtaaacga gattccaagg ggatttatcg cttagattta ccgacaggag ctggcaagac
    38101 taatcttagt atgcgttatg cgtttcacca attagttcat cacgacaaat caaggttttt
    38161 ttacataacg ccctttcttt cggttcttga gcaaaatgct tccgaaatta gaaaagttac
    38221 aggtgacctt ggcgttctag aacaccattc caatgtggtg aaacaggcta atgaagatga
    38281 tgatgataag gacagtttat tgtcagctta tcttagtgat agctgggaca gtcaagtagt
    38341 cttgacttct atggttcaat ttttccaaac acttttcaaa acaaaatcag ctaatctgag
    38401 acgtttttca agtttgatta atagtgttgt gattctagat gaagttcaat ccctgcctat
    38461 tgaagtcacc actttgttta atttaacgat gaatttttta aataaagtta tggatacaac
    38521 catcgttctt tgcacagcga cacaacctgc ttatgattct tcagagattg accatcgtat
    38581 ctgttatgga gggaacttgg gagaattagc tgaaatagtt gagttaacga ttgaagaaaa
    38641 acagattttt tcaaggacag agcttagaaa atttgatgat agtgatcaga aagttcactt
    38701 gactgatgtt attaacctta ttctaggtga ggaaaactca gttcttgcta tttttaatac
    38761 gaaaaaaacg gttcataact gctatactat gctaaaagac atgactgata gaccggtcta
    38821 tcagctttcg acaaatatgt gtgcgcagca tagacttgac ttgattgcta agatcaaaac
    38881 ggagttacaa aataatatcc ctattatttg tattagcacg caattaattg aagcaggtgt
    38941 agatgttgat tttcatcgcg tcattcgttc ctactcaggg attgattcta ttgttcaggc
    39001 tgctggacgg tgtaaccgag aaggcaaacg agataaaggg caagtcactc ttgtcaatct
    39061 gaccaatgaa gaggaaaata tttctaggct gacagaaata aaaactaaaa aagaagccac
    39121 agaatctatt cttcataaga ttgggtctcc aattgatatc tcaactttaa accgtgactt
    39181 ttttgagtat tattatgcca ataatcaggg actgatggat tatcctttgg aagacaacct
    39241 atcaatctac gactatttaa gccttaatat ttatcagacg gcaaataaaa agttcaaagg
    39301 taagttaaaa caagctttta aaacagcagg agccaaaatg aacctcatca ataatgatat
    39361 gataggaatt ctcgtacctt atggcgaagc tgagaaaaaa ttggcttatt tagaagaatt
    39421 aggtgtgtca cattttttat cagcaaaaga ttatcaaacg ataaaatcat tactaaaaga
    39481 gttacaacct tttacggtta atgtccgcga gaacgatcct ctctttgaga caacaaaatc
    39541 ttatctaaat ggtcagattc tggttttgac gtcggagtat tatgacacgg aaagaggagt
    39601 taaatacgat tcagctagct tttacttcta actcaaaacg aaagaagatt aacaaaaggt
    39661 tgttagagga ccttgttaac ctgccaatca tcattagtaa ttattatcaa tttagactat
    39721 ttaataaaat tagattacaa aaaaacagaa ggaggaaagt agcttgtaca gatctagaga
    39781 cttctacgtg agagtaagtg gtcagcgagc tctttttaca aatccagcca caaaaggggg
    39841 atcggaacgc tcatcctatt cggttccgac tagacaggca ctgaatggta tcgttgatgc
    39901 catctattat aagccgacct ttactaatat cgtcacagag gttaaggtta ttaaccagat
    39961 tcaaaccgaa ttacagggtg tcagggctct gttacatgat tatagtgcag atttaagtta
    40021 tgtatcctat ttgagtgatg ttgtttatct gatcaagttt cattttgttt ggaatgaaga
    40081 tagaaaagat ttgaactcag atagacttcc agctaaacat gaagccatta tggagcgttc
    40141 tattcgtaaa gggggacgtc gagatgtgtt tttgggtaca agagaatgtt tagggcttgt
    40201 agatgatatc agccaagaag agtatgagac tactgtgtcg tattataatg gtgtcaatat
    40261 cgacttggga atcatgttcc attcctttgc ctatccgaag gacaaaaaga caccattaaa
    40321 atcatacttt acaaagactg tgatgaaaaa tggagtcatt acgtttaaag cacagtctga
    40381 atgcgatatt gttaacacgc tttctagtta tgcttttaaa gcaccagagg agataaaatc
    40441 ggttaacgat gaatgcatgg agtatgatgc catggagaaa ggagaaaact gatggatttt
    40501 tttacttctc tcttgaagac ttatgaaaaa gcagagctag cagacttggt tgatcatcaa
    40561 aaaagaaata atgagccggt tttactgccg atttatcata cgagtttaaa gtcaaatggt
    40621 aaaaatatca tttcagtgaa acttgacaaa gatggccagt ttcacaaggc agaatttatg
    40681 gcagataagc aaatgattat ttttcctgta acggctgatt ctgttgctag gtcaggtagt
    40741 catcctgcac cgcatcccct agtcgataaa tttgcttatt atagtgctga aatggggcag
    40801 attcagtatg attcttttca taagcaactg aataactgga ttgattattg tgaggagggt
    40861 gatgtcaaga aatttttaac ctttgttcag cagttcattt tgaagccaga atttctaaca
    40921 ttgattcttg attctttaat tggtcctgat tatcaacata atcaattaaa agtcacattt
    40981 tgtgatgcca ctggaaaaga aaaattaatt gatttatcag cttgcttttt agaattttca
    41041 attgatcagt tccagggctt taaaaatgaa tcggtttcga catttaaagc cttacaccaa
    41101 tcctatattt cttttgttga agccaatcgt gaaaatctcg gtatttgtaa tattagtgga
    41161 cgagaggaac agcttaccga taagcataga ggtttgatgg ggaatgctaa aatcatctct
    41221 gttagtaata aaagagaagc ttataaagga cgttttagag aacgcgaaga cgtttttagt
    41281 gttggctatg aaacttccga aaagattcat ttaatgctca agtacctttt agaaaataaa
    41341 aataccagta cttggttagg gtcttctcaa tatttaatca actggttcag cgatgattta
    41401 acaaatgata gtcggttgga tattgtatca ccaatctttg atgatggact tgaagaagaa
    41461 gatgatgacg atacgcctcc tgttataaca ttagcaactg aagacaataa aagaattggt
    41521 aaatcattca tcaagggaca aaaattattt gctaatgatg ccacttacta cgttgctatt
    41581 ttgaataaaa ccagcaatgg gcggattgct ttaaaatatt ttcgtcagct tcaagcgtcc
    41641 caattactca ccaatcttaa caagtggcag gaaacataca gttgggagtc gcgatctaag
    41701 tttgggaaaa gtcgcttaag aacccctact tttcatgaca tccttaatgt gtcctacggg
    41761 gttgataggg atcgcttcct tgaattagat aatgataact tcaaaagtga tcaaattcaa
    41821 aagttagtgg caagtttgat tgatggtaaa ccgatgccac agtccattgt caaaaagtta
    41881 ggtaacaatg ttaaagaacg acatcgttac cgtaagcact ggtatcaagt tgagcaggtc
    41941 tgcttagcaa ttttacacaa acaaaatggg gaggaatttt caccgatgct agatcatacc
    42001 aatcaaaatc gttcctatct ttttggacga ttattagcaa tttttgaatt aatcgagacc
    42061 ttgcgttatg gcttggatgg aaacaataac gaccgtatta ccaatgctga acgttattgg
    42121 acagcctata ctggacaacc aacaaaattg atgatgttat tggaaaataa aattaagcct
    42181 tacgaagaac cattgaaatt aaatcgtcgt ggcagttgga tgaaattaga aaaagaaaaa
    42241 gaagagattt tagaactgtt aaatcctctg ttagaaacag aaacaatgga aaaaccctta
    42301 gattaccgct ttatttttgg gtattatgct gagaaaaact attactatac aaaacaaaac
    42361 acggaagtaa cagaaagtga ggagtaaaaa gatgttggaa cacaaaattg attttatggt
    42421 aactcttgaa gtgaaagaag caaatgcaaa tggtgatccc ttaaatggaa acatgcctcg
    42481 tacagatgcc aaaggatatg gtgtgatgag tgatgtctcc attaaacgta agattcgtaa
    42541 tcgtttgcaa gatatgggga agtctatttt tgtgcaagct aatgagcgta ttgaagatga
    42601 ttttcgttca ctggaaaaac gcttttcgca acattttaca gctaagacac ctgacaaaga
    42661 aattgaagaa aaagcaaatg cattatggtt tgatgttcgt gcttttggac aagtttttac
    42721 ttatctgaaa aaatcaattg gggtgcgtgg accagtttcc atcagtatgg ctaagtcctt
    42781 ggagccaatt gtcatttcca gccttcaaat tacgcgtagt accaatggta tggaagctaa
    42841 gaataatagt ggccgctctt ctgatacgat ggggacaaaa cattttgtag attatggtgt
    42901 gtatgtactt aaaggttcta tcaatgctta ttttgctgaa aagactggtt tttctcagga
    42961 agatgctgag gctattaaag aagttttggt tagcttgttt gaaaatgatg cgtcgtctgc
    43021 acgtccggaa ggctctatgc gagtttgtga agtcttttgg tttacgcatt caagcaaatt
    43081 gggaaatgtt tcaagtgcgc gtgtctttga cttgttagag tatcatcaat caatagaaga
    43141 aaaaagcact tatgacgctt atcagattca tctaaatcaa gaaaaattgg ctaaatatga
    43201 agcgaaaggg ttaacgcttg aaatcctaga aggactctag tatggtctat gccgaagatg
    43261 attatttaat gctgtcaggt attcagcatt tccaattttg taaacgtcaa tgggcgttga
    43321 tccatattga gcaacaatgg cttgataatg aagcgacagc gcatggacag gttttacata
    43381 ctaaagcaga taacccttac attaaagaaa aacgaaaaga gcttttggtc tcacgtgcta
    43441 tgcccatttc ttctgcagaa cttggacttt caggaattat ggatgttgtg gaattttata
    43501 aagatgatca aggtgtgtct ttgaggggaa aacgtgggaa atggttacca aaagttgtgg
    43561 aatacaagcg cggaaaacct aaaaaagata ccagagatat tgtccagttg gtggctcaga
    43621 ccatgtgttt agaagaaacg ctagactgcg acattaacga aggttgtctt tattaccata
    43681 gtgtcaatca aagagtgatt gttcctatga catcagcttt gcgtcaagaa gtgaaggaat
    43741 tagccgcaga gatgcatgag gtttatcaga gtcaaatgct acctaaagca gcttatttta
    43801 aaaactgtca gctttgttct ttagtcgata tttgtaagcc caggttgagt aaaaaaacaa
    43861 ggagtgtgtc gcgttacatc aatgaggcta tgaccagtga ggagatggac ctatgaagaa
    43921 gttgctaaat accttgtatt tgacgcaaga agatttttat gtcactaaag agggcgataa
    43981 cattgttatc aagcaagaag gtaaggttct caaacggttt ccgtttcgga ttattgacgg
    44041 tattgtctgt ttttcttatt tgggtgtgtc gtctgctttg gtgaagttat gtacggagaa
    44101 tcagattaat ttatcgtttc atacaccaca agggcgtttt tgtggtcgct atattggttc
    44161 aaccaatggg aatgtgttgt tgcgtagaga acattatcgt ttatctgatc gtgaggaatc
    44221 tttggaatac gcaaagcggt ttattttggc taaaatttcc aactcaagga aatacttgct
    44281 acgctttaaa cgagatcatc gtcaacagat tgataccaag ctttttgagg ctgttaatga
    44341 cgaattgata tgggctttag agatggttca ggcagcagat aataaagact ctttaagagg
    44401 gattgaaggc caagctgcta atcagtattt tcgcatattt aatgacctgg tgttgacgga
    44461 caaaaaaacg ttttacttcc aaggtcggag taaacgacca cccttagatt gtgttaatgc
    44521 cctcttgtct tttggttaca gtttactgac ctttgaatgt caatctgcct tggaagctgt
    44581 cggattagac agttacgttg gtttctttca cacggatcgt cctgggcgtg ctagtttagc
    44641 gcttgattta gttgaagagt tccgctcata tattgtagat cgttttgtct tttcattaat
    44701 taataaagga caacttcaga aaaaacactt tgaggttaaa gaaaatggta gtattttatt
    44761 gacggaaaat ggcagagcta tttttattga tttgtggcag aagcgtaagc atactgaggt
    44821 agaacatcct tttacaaaag agaaagtaaa acttatgtta ttaccctatg tacaagcgca
    44881 gcttttagct aaggctatac gaggagattt agaaagctat ccacctttta tggtttagga
    44941 gatgttatat gatggtttta gtcacttatg atgtaaatac ggaaacacct gctggtagaa
    45001 aaagattgcg tcatgttgcc aaactctgtg tggactatgg gcaacgtgtt caaaattctg
    45061 tttttgaatg ttctgtgaca cccgcagaat ttgtggatat aaagcaccgc ttaacacaaa
    45121 tcattgatga gaaaactgat agtattcgct tttatttatt ggggaaaaat tggcagaggc
    45181 gtgtggaaac acttggtcgc tcagacagct atgacccaga taaaggtgtc ttattattgt
    45241 aaaaatctct tgtgcgaagc tagctttcac agaaacacct tgcttgctcg cgcaaaaata
    45301 acttaaaaaa gaagcgaaat ggagataaaa aggcttaaaa cacctctatg tgtgccatcc
    45361 gtttctctat aaactgtgtc atttggcgca gtctcaccct tcatgggtga gtggatcgaa
    45421 ataaaaagca tatcacgaaa atcaccaatt acatcaggtc tcacccttca tgggtgagtg
    45481 gattgaaata agtcattttc tgcttctgct aggtttgctt tagtctcacc cttcatgggt
    45541 gagtggattg aaatttttta ctttgattac atcccgcaat gtcacagcgt ctcacccttc
    45601 atgggtgagt ggattgaaat tgtccgcata ccttgatttg agcgagtaaa ctcgtctcac
    45661 ccttcatggg tgagtggatt gaaagatgaa cccgatctct cttttaatga ggtcgggttt
    45721 ttacatgcct ttagtcaacc atttatctga tagcgtatca aattcaagtt tttgcatgtt
    45781 ctagtctatg gtttgcgcca ctagctttcg gtaaactaag ggtaacttaa gagaggagtt
    45841 atttatgaca ctatcacttg tattaatggt atcggttttt ggggcaggct tgttatcctt
    45901 tttctctccg tgtatctttc cggtccttcc tgtctattta ggcattttac tggatgcaga
    45961 tgattcaaag acgattacta tatttggtaa aaaactctat tggtatggca ttgtcaaaac
    46021 tttagccttt atttttggtc tatctactat ttttgtgatt ttaggttacg gggctggttt
    46081 tttaggaaat atcctttatg cggtatggtt tcggtactta ctgggagcct tggtcattat
    46141 cttggggatt catcagatgg gcctcattac cattaagagc ttacaatttc aaaaatcact
    46201 gactttccat aataacaaga atcgcaacgg tttgttcaat gcatttatcc ttggtttaac
    46261 ctttagcttt ggttggacgc cttgtgtggg acctgttttg agttctgtcc tagcattggt
    46321 ggcttcaggg ggaaatggtg cctggcaagg tggcgttttg atgattattt atactcttgg
    46381 attgggcatt cctttcctac tcatctcttt tgcgtcaggc attgttttga aacagtttaa
    46441 caagctcaaa ccccacatac ttttactgaa aaaagtagga ggcgttctga ttatagtcat
    46501 gggaatcttg cttatgacag gaaccttaaa taacttagca caactttttg gataaaggag
    46561 aaacacaatg aaaaaaggac tattagtaac aactggtttg gcttgtctcg ggctactaac
    46621 tgcttgctca acccaagaca atatggctaa aaaggaaata actcaggaca agatgagcat
    46681 ggcagctaaa aagaaagata agatgtcaac atcaaaggac aagtccatga tggcagataa
    46741 atcatctgat aagaaaatga ccaatgatgg tcctatggcg cctgatttcg aactcaaagg
    46801 catcgatggt aagacctatc gcttatcaga gttcaaaggt aaaaaagttt atttgaaatt
    46861 ttgggcctct tggtgttcaa tctgtctatc aaccttggca gataccgaag acctggctaa
    46921 aatgtcagat aaagactatg tggtcctaac agttgtctcg ccaggtcatc aaggggaaaa
    46981 atcagaagca gactttaaaa aatggttcca aggaacagac tataaggact taccagtctt
    47041 gttagatccg gatggcaagc tattggaagc ttacggtgtc agatcttacc caacagaagt
    47101 tttcattgga agtgatggtg ttcttgctaa aaaacacatt ggttatgcca aaaaatcaga
    47161 catcaaaaag acccttaaag gtatacatta ggaaggacca gctgataggc attagaaaaa
    47221 aggagttgag tttatggaac ataaatggaa attatggcta tttatcgttg gagtggtctt
    47281 gttaataggc ggagcttctg ttctcattca gaaaggtcaa gccaaggctt ttagtcaagg
    47341 caagcctcaa ctaccagcta aaaaagtcaa atccactaaa gtagatccca atgcccctgt
    47401 tgatcaaaaa gtgatttacc tggctggagg ctgtttctgg ggcgttgaag aatatttttc
    47461 acaagtggat ggcgttctag atgcggtgtc aggctatgcc aatggtagag gcgataccac
    47521 caactaccag ttaattcatc agactggtca tgcagaaacc gttgaagtgg cctatgatgc
    47581 gaaccgtatt agcttgaaag aattattact gcattttttc cgaattattg acccaaccag
    47641 tcttaataag caaggaaatg atcgcggtag tcaataccga actgggattt actatactga
    47701 caaagcagat ttagctatta ttgatgaggt cttcaaagaa aaagctaagg attacaagaa
    47761 aaaaatagtg gttgaaaaag caccattgaa acactttatt aaggcagaag actaccacca
    47821 agattacctc aagaaaaatc caaatggcta ctgccatatt gacatcaacc aagcgactta
    47881 tcctgtgatt gatgaaagca agtacccaaa accaagtgcc actgagatca aggaaaaact
    47941 atctgcagac gaataccgag tgacgcaaaa aaacgaaact gaaaaagctt tttctaatcg
    48001 ctactgggat tcttttgatg caggaattta cgtagacgtt gtgacaggag aaccgctttt
    48061 ctcttcaaaa gacaaatttg aatcaggttg tggttggcca agctttagcc gccccatcag
    48121 cccagacgtt gtccgctaca aggaagataa gagtttcaat atgacgagaa cagaagtgcg
    48181 cagccgttca gggaattctc atctggggca tgtctttact gacggaccta aagaccaagg
    48241 cggccttcgt tactgcatca atagcttgtc tattaccttt attccaaaat ctgatatgga
    48301 agctaagggc tatggttatt tattatcatc tgtagaatag ggttaggcct aaaaatctga
    48361 tataatagaa gaaagactag tatgagaggg ccatgcaagg ccctttataa agataaggag
    48421 acaccgtgtg tactcattgt taattgtaga agacgaatac cttgtgcgcc agggtattcg
    48481 ttctttggtt gattttagcc agttcaagat tgatcgggtc aacgaagcag aaaatggcca
    48541 gttggcttgg gacttgtttc agaaagagcc ttatgatatt gttttgacgg atatcaatat
    48601 gcccaaatta aatgggattc aactagcaga actcattaaa caggaatccc cccaaactca
    48661 tctggtattt ttgacgggct acgatgattt taactatgcc ttatctgctt tgaaattagg
    48721 ggcagatgat tacttgctca aacccttttc caaggcagat gtagaagaca tgttaggaaa
    48781 gctccggaaa aaattagaac tttccaagaa aacagaaacc attcaggaat tggttgagca
    48841 gcctcaaaaa gaagtatcag caatagcaat ggctattcat gagcggttgg cagattctga
    48901 tttgacccta aaaagcttgg ctcagcagct tggttttagc cctaattacc ttagcgtctt
    48961 gattaaaaaa gagttaggga tgccctttca agattatctg gtacaagaac ggttgaaaaa
    49021 agccaagctt ctcttgttaa ccagtaatct taaaatctat gaaattgcag agcaggtcgg
    49081 ttttgaggac atgaattatt tttctcagcg ctttaagcaa ctggtaggcg ttaccccaag
    49141 tcagtataaa aaaggaggcc aggcatgaag cgttatcccc tactggtcca gttgatttcg
    49201 tatgtttttg tgatcgtaat tgccctcatt accacgcttg gtttgcttta ttaccagacg
    49261 agttctcgta atatcaggca actaattgaa cgtgataccc ggcagagcat tcggcaaagt
    49321 tcccaattta ttgacgctta catcaagcct cttaaagaaa caacttcggt gctggcgaaa
    49381 aatacggaaa ttcaagcctt tgctagtcaa attcatcaag aaaatgacaa acaggttctt
    49441 cagctcatga agatggttct tgcgaccaat tccgatttac aagcagctgt tctggtgact
    49501 aaggatggtc gaacggtgtc taccaattct cagttgacca tgaaaacctc cagtgacatg
    49561 atggcagaac cctggtataa agcagccata gaccgtcaag ccatgccaat cttaacccca
    49621 gctcggcaat tatccctttc ttctaaaaaa gaatgggtag tttctgtgac ccaagaggta
    49681 gtagataggg ctgggcataa tttaggtgtg ctaagacttg atattgcata cccgaccatt
    49741 aaagcgtctt tagatcagct tcagctaggc cgccaaggct ttgcctttat tgtgaatgat
    49801 aagcatgaat ttgtttacca tcccaaaaag agtgtttaca gttcttctaa ggagatggct
    49861 gcgatgaaac cttatttagc gattcagaat ggttacacta aggacaagac atcttttgtt
    49921 taccaaaaac tcattcctaa cagtcaatgg actttagtgg gagtggcgtc actggatcag
    49981 ttgcaccggg tgcagcgcca aattttttgg tcctttcttg gaacagggct tctagcctgt
    50041 ctgatttgtg gctttgcaac tgtcttagtc ttacgcagat ggattcgtcc cattcaacaa
    50101 ttgcagcaag ttattcttgc tattcaaaaa ggagatcgtc agttacgtgc ccaagaaacg
    50161 ggttctccag aattgacaga ccttgcccaa cagtttaatg cgctcttaga tcaaattgat
    50221 agcttgatgg ttgccgttgc ggataaggaa aaggcgattg ggcagtatag gttacaagcc
    50281 ttggctagtc agattaaccc gcattttctc tataacacct tggacactat tatttggatg
    50341 gcagaattta atgacagcaa gcgcgtggta gaagtgacca agtctctagc taagtatttt
    50401 cgtttggccc ttaatcaggg gaacgaatac attcgtttgg cagatgaact ggatcacgtt
    50461 agccaatacc tctttattca aaaacagcgc tatggagaca agctaagtta tgaagtgcaa
    50521 ggcttagatg tctacgcaga ctttgttatt cctaagctta tcttacagcc cttagtagaa
    50581 aatgctatct accatggcat caaagaagtc gatcgcaagg gcatgatcaa ggttacggta
    50641 tctgatacag ctcagcatct gatgttgact gtttgggata atggtaaagg cattgaagac
    50701 tcttcactga ccaatagtca gagcttgttg gctaggggag gtgtgggcct taaaaatgtt
    50761 gaccagcggt taaaacttca ctatggtgaa ggctaccaca tgaccattca tagccagtca
    50821 gaccagttca ctgaaataca attaagcctt cctaaaatgc atgaattaat ggcagacgac
    50881 acacaggaaa acgagtaagg ttacaggaag tgcatgtcag ccatttccct aagttagggt
    50941 attggagata ggaaccttag aaaggatatc atgagtttag caactgacta ttttagccga
    51001 cagaccccca tagttgaaaa gctaatggct tacggttttg agaagcgaga caacggttat
    51061 ttctataacg aacggtttat ggaaggggaa tttgaggcgc agcttaggat tgatgaggct
    51121 ggcaatatct gggatcgggt tattgattgt gacttggagg aggattattt gcctttacaa
    51181 caagcagcct ggcaaggaac ctatactggg caggttagag cggcctattt ggaacttttg
    51241 gagcgcttat cagtagcctg ttttgaagcc actccttttc agtcaatgca agctaataga
    51301 cttgctaagc atatcaccaa agaatggtct gacccaatgg actatccttt tgaaaagcac
    51361 ccagaccttg caacctatcg ggtagggggc aaatggtatg ctatgatttt ttctctcttg
    51421 gctgataaat tagaccagat accagagaga ttagtaggac agacatgtga agtgatgact
    51481 gtcaaagtta atcccaaggc tttccctcag ttactgcagc aagaaggcat ttacccagcg
    51541 tatcacatgt caaagaaaaa ctggattagt attattttgg atgataaggt aacagatgat
    51601 aagctttgga cgttagtgac tcaaagtcgt caactagtca acccaaacgg tctttctaat
    51661 cctaatggtc ctgattattg ggttattcca gctaatttga aatactatga cattgatgca
    51721 gaatttgcag ccaatgatgt gattttatgg acccaaaaag ctggtattgc cgtgggagac
    51781 tacgtgctga tttatataac agccccagtc aaatccattc gctatgtctg ccaagttcta
    51841 gaaactgata tacctaacga gggttatcgt aaaaatccta acattgacaa actcatgcgt
    51901 ctccgaaaat gccaacagta caaggatggt ctcttgtctt ttgaccttat gaaaaaacat
    51961 ggcgtagctg cagtgagagg gccaagacga ttaagccctc aattaattgc atttttaaag
    52021 gaaaaagagt attttaaaga gaacaactaa aggagaataa gagatggttg aatttgtagc
    52081 agatcaaagt ttttgggaac tttttccagg tgccaaacta ggtgtcgtct tattaaagga
    52141 tgttcagaac caagcagagt caccagaaga tgtcaaacag ctcttagcag acagccatga
    52201 gttagcaaaa gcttatttaa cagcagacaa ttttagtgat aatcaggtgg ttcaagtcta
    52261 ccgcaaggcc tatcaacact ttaaaaccaa aaaaggagct cgctctagca ttgaagccct
    52321 tctcaagcgg gtgtcaaatg gtcaaagcat tccgtctatt aacccactag tggatattta
    52381 taatgcggct agtctacgtt ttggtttacc tgctggagcc gaagatagtg acagttttat
    52441 cggagatttg cgtctgacga taacagatgg tggtgacgac ttttacttga ttggggatgc
    52501 tgacaacaac ccaaccttgc caaatgaact ctgttataaa gatgatattg gagcggtttg
    52561 tcgttgcctt aactggcgag atggcgaacg caccatggtg acagaacaca ccaaaaatgc
    52621 atttctgatt atcgaagctc ttgatcaaga aggtcaaaat agattgcaag aagctctgaa
    52681 attcattgaa ggcagcgcaa aaatgtacct tcatgcaatc acttctgtgc atgtgttgga
    52741 taaagacaat ccacacgtgc cactttttac agaaaactag attagtagga tgagctgtgt
    52801 aaaaatagaa ggttaacaaa aagcgagtaa acgaatgtcc tgtcatttag gttttcgttt
    52861 actcgctttt tgatgagatt ttactgctgt cctagcaaaa ggtgaggatg aggtcgtata
    52921 tcacatagag gttttctgtt aagccttatt tgttactaaa gaagaatggt ggcgtgtaat
    52981 gactaagggt ttcgtaacag gccttagctt gctcattgtc ttcacagaca atcaagcaag
    53041 tatcatcacc acagaccgtt gctacaattt ctggaatttg catggcatct aaaatggagc
    53101 caaaggattg ggctagtcca ggtaacgttt ttaaaataat ttgatgttga actatcttta
    53161 acatgaccaa agcgtcttcc atgtaaaaac gaagacgatg ttcccagcgg gtttgtgaaa
    53221 tggctaacgc ttcatagtgt gtgtcgtttc cagaagttac tttgaccagg ttcaattcct
    53281 tcatgtcacg tgatagggta gcctgagtga tcgtgatgcc atttttttgc aaccgttctt
    53341 gtaattcttg ctgtgtatgt atagttgtct cagagatgag ggaacgtatg agttggtgac
    53401 gcgtctcttt cttattcatt gttataatct tcctttaacg taattgataa caatccgagt
    53461 atagcaaaaa gaggagaagg tgtaaagttt ttgatgaacc gcttacaaaa tggctttttt
    53521 atggtaaaat aaagatgatg tttagaaaaa ggagatttgt gtgattcgaa gagaagatta
    53581 tcaatacctt agaaaactaa acgattttcg ctacttttct attgaacaat ttgacaaaat
    53641 tgtagggcag atggaattcc gaaaagctaa aaaggaccat atcctttttt ttgagggaga
    53701 taaaagagat aagctttttc tagtgacctc tggttatttc aaggtggagc agtccgatca
    53761 atcaggaacc ttcatgtata cggatttcat cagacacggc accatttttc cttacggtgg
    53821 cctctttaca gatgattatt accatttttc agtggtagcc atgacagacg tgacttattt
    53881 ttactttcca gtcgatttat ttgaagatta ttcgcttgaa aatcgtctac aaatgaaaca
    53941 cttatatagt aagatgtcta agctgctcga gttacatgag ttgagggtcc gaaacttgat
    54001 tacatcaagt gctagttctc gtgtgattca atctctggcg attttgctgg ttgaaatggg
    54061 taaagacagt gataccttac cttttcaatt aacaacaaca gatattgctc aaataagtgg
    54121 gacgacaaga gaaacagtta gccatgtgct tagagatttg aagaagcaag aattgattac
    54181 cataaaaggt aagtatttga cttatctaga taaagactat tttttacaat acacaaagtg
    54241 aa
//
LOCUS       DAUGQX010000005        53777 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUGQX010000005 DAUGQX010000000
VERSION     DAUGQX010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53777
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.005"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            52..765
                     /locus_tag="VIA51_000242"
     CDS             52..765
                     /locus_tag="VIA51_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8682217.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            762..1673
                     /gene="pfkB"
                     /locus_tag="VIA51_000243"
     CDS             762..1673
                     /gene="pfkB"
                     /locus_tag="VIA51_000243"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEQ8682218.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISQEQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            1670..3616
                     /locus_tag="VIA51_000244"
     CDS             1670..3616
                     /locus_tag="VIA51_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8682219.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            3709..4308
                     /locus_tag="VIA51_000245"
     CDS             3709..4308
                     /locus_tag="VIA51_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8682220.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            4460..5167
                     /locus_tag="VIA51_000246"
     CDS             4460..5167
                     /locus_tag="VIA51_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8682221.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(5224..5559)
                     /locus_tag="VIA51_000247"
                     /pseudo
     CDS             complement(5224..5559)
                     /locus_tag="VIA51_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(5739..6082)
                     /locus_tag="VIA51_000248"
                     /pseudo
     CDS             complement(5739..6082)
                     /locus_tag="VIA51_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6123..7142)
                     /gene="ideS"
                     /locus_tag="VIA51_000249"
     CDS             complement(6123..7142)
                     /gene="ideS"
                     /locus_tag="VIA51_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin G-degrading enzyme IdeS"
                     /protein_id="HEQ8682222.1"
                     /translation="MRKRCYSTSAAVLAAVTLFVLSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKDQIKRYLEEHPEKQKINFNGEQMFDVKEAIDTKNHQLDSKLFEYFKEKA
                     FPYLSTKHLGVFPDHVIDMFINGYRLSLTNHGPTPVKEGSKDPRGGIFDAVFTRGDQS
                     KLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGN
                     LKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDS
                     WNQTN"
     gene            7641..7891
                     /locus_tag="VIA51_000250"
                     /pseudo
     CDS             7641..7891
                     /locus_tag="VIA51_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8045..8425
                     /locus_tag="VIA51_000251"
     CDS             8045..8425
                     /locus_tag="VIA51_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEQ8682223.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            8425..9273
                     /locus_tag="VIA51_000252"
     CDS             8425..9273
                     /locus_tag="VIA51_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8682224.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVFIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            9398..10606
                     /locus_tag="VIA51_000253"
     CDS             9398..10606
                     /locus_tag="VIA51_000253"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEQ8682225.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDIYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAITFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDYHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDR
                     INTLDQALVIHDKHDIVLNGSHLIKDFGMKSGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            10603..12480
                     /locus_tag="VIA51_000254"
     CDS             10603..12480
                     /locus_tag="VIA51_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8682226.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSADVKAIQLIRQ
                     YELLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFSDLKKEVHQDSSADKLEMTFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLKVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRVFYGNYSDYLDEKVFEKETVEADLAKTTVTEEVPLPQKEERKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(12578..12655)
                     /locus_tag="VIA51_000255"
                     /pseudo
     CDS             complement(12578..12655)
                     /locus_tag="VIA51_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            13372..13782
                     /locus_tag="VIA51_000256"
     CDS             13372..13782
                     /locus_tag="VIA51_000256"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8682227.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(13864..15876)
                     /locus_tag="VIA51_000257"
     CDS             complement(13864..15876)
                     /locus_tag="VIA51_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEQ8682228.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTKDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDVAETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATVMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSAN
                     VVAVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     ATTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGV
                     KNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNTVSSEVISDLLTSTENTNNSLGKKE
                     TTTNKNTISSSTLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     gene            16096..16746
                     /locus_tag="VIA51_000258"
     CDS             16096..16746
                     /locus_tag="VIA51_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8682229.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            16749..17417
                     /locus_tag="VIA51_000259"
     CDS             16749..17417
                     /locus_tag="VIA51_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682230.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            17426..18658
                     /locus_tag="VIA51_000260"
     CDS             17426..18658
                     /locus_tag="VIA51_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8682231.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSVMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            18952..19830
                     /gene="mvk"
                     /locus_tag="VIA51_000261"
     CDS             18952..19830
                     /gene="mvk"
                     /locus_tag="VIA51_000261"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEQ8682232.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYASLDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            19812..20756
                     /gene="mvaD"
                     /locus_tag="VIA51_000262"
     CDS             19812..20756
                     /gene="mvaD"
                     /locus_tag="VIA51_000262"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEQ8682233.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGILQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDQWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            20749..21756
                     /locus_tag="VIA51_000263"
     CDS             20749..21756
                     /locus_tag="VIA51_000263"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEQ8682234.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKEIHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEN
                     D"
     gene            21749..22738
                     /locus_tag="VIA51_000264"
     CDS             21749..22738
                     /locus_tag="VIA51_000264"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEQ8682235.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(22968..24245)
                     /locus_tag="VIA51_000265"
     CDS             complement(22968..24245)
                     /locus_tag="VIA51_000265"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEQ8682236.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(24232..25407)
                     /locus_tag="VIA51_000266"
     CDS             complement(24232..25407)
                     /locus_tag="VIA51_000266"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEQ8682237.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDLAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASISYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            25616..26455
                     /locus_tag="VIA51_000267"
     CDS             25616..26455
                     /locus_tag="VIA51_000267"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEQ8682238.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDRTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            26535..27032
                     /locus_tag="VIA51_000268"
     CDS             26535..27032
                     /locus_tag="VIA51_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEQ8682239.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRVIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            27052..27222
                     /locus_tag="VIA51_000269"
     CDS             27052..27222
                     /locus_tag="VIA51_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682240.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            27352..28581
                     /gene="clpX"
                     /locus_tag="VIA51_000270"
     CDS             27352..28581
                     /gene="clpX"
                     /locus_tag="VIA51_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEQ8682241.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            28591..29190
                     /locus_tag="VIA51_000271"
     CDS             28591..29190
                     /locus_tag="VIA51_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEQ8682242.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            29338..30081
                     /locus_tag="VIA51_000272"
     CDS             29338..30081
                     /locus_tag="VIA51_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682243.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(30139..32238)
                     /locus_tag="VIA51_000273"
     CDS             complement(30139..32238)
                     /locus_tag="VIA51_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8682244.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVN
                     QTTAKKGISLTITDDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQNDQ"
     gene            32617..33300
                     /gene="rpiA"
                     /locus_tag="VIA51_000274"
     CDS             32617..33300
                     /gene="rpiA"
                     /locus_tag="VIA51_000274"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEQ8682245.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKNFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPTAG"
     gene            33377..34588
                     /locus_tag="VIA51_000275"
     CDS             33377..34588
                     /locus_tag="VIA51_000275"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEQ8682246.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     AAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGDPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSVSFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLSHLK"
     gene            34607..35047
                     /gene="arsC"
                     /locus_tag="VIA51_000276"
     CDS             34607..35047
                     /gene="arsC"
                     /locus_tag="VIA51_000276"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEQ8682247.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAYGLANQAVAEKDIINAMLADPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYIKEDGESVNPIEVKGEKDVIDD"
     gene            35031..35840
                     /locus_tag="VIA51_000277"
     CDS             35031..35840
                     /locus_tag="VIA51_000277"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8682248.1"
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            36503..37216
                     /gene="deoD"
                     /locus_tag="VIA51_000278"
     CDS             36503..37216
                     /gene="deoD"
                     /locus_tag="VIA51_000278"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8682249.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            37209..37997
                     /locus_tag="VIA51_000279"
     CDS             37209..37997
                     /locus_tag="VIA51_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEQ8682250.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(38076..38981)
                     /locus_tag="VIA51_000280"
     CDS             complement(38076..38981)
                     /locus_tag="VIA51_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8682251.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            39203..39739
                     /locus_tag="VIA51_000281"
     CDS             39203..39739
                     /locus_tag="VIA51_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682252.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKVPTGEFE"
     gene            40016..40708
                     /gene="pyrF"
                     /locus_tag="VIA51_000282"
     CDS             40016..40708
                     /gene="pyrF"
                     /locus_tag="VIA51_000282"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEQ8682253.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYVQG
                     PDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGAVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            40766..41395
                     /locus_tag="VIA51_000283"
     CDS             40766..41395
                     /locus_tag="VIA51_000283"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEQ8682254.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIKAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            41592..43046
                     /locus_tag="VIA51_000284"
     CDS             41592..43046
                     /locus_tag="VIA51_000284"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEQ8682255.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPRDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LSMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            43164..44027
                     /locus_tag="VIA51_000285"
     CDS             43164..44027
                     /locus_tag="VIA51_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8682256.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHQSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYHAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            44056..44706
                     /locus_tag="VIA51_000286"
     CDS             44056..44706
                     /locus_tag="VIA51_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8682257.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            44839..45492
                     /locus_tag="VIA51_000287"
     CDS             44839..45492
                     /locus_tag="VIA51_000287"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEQ8682258.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            45624..46892
                     /locus_tag="VIA51_000288"
     CDS             45624..46892
                     /locus_tag="VIA51_000288"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEQ8682259.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(46950..47591)
                     /gene="plsY"
                     /locus_tag="VIA51_000289"
     CDS             complement(46950..47591)
                     /gene="plsY"
                     /locus_tag="VIA51_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEQ8682260.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            47726..49675
                     /gene="parE"
                     /locus_tag="VIA51_000290"
     CDS             47726..49675
                     /gene="parE"
                     /locus_tag="VIA51_000290"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEQ8682261.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKIAYAWTDGEL
                     EDLRREFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            49766..52225
                     /gene="parC"
                     /locus_tag="VIA51_000291"
     CDS             49766..52225
                     /gene="parC"
                     /locus_tag="VIA51_000291"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEQ8682262.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            52303..53370
                     /locus_tag="VIA51_000292"
     CDS             52303..53370
                     /locus_tag="VIA51_000292"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEQ8682263.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            53434..53664
                     /locus_tag="VIA51_000293"
     CDS             53434..53664
                     /locus_tag="VIA51_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEQ8682264.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
BASE COUNT        16844 a         9352 c        11069 g        16512 t
ORIGIN      
        1 atttcagtta ggggtggttc tatcttaaaa tcaaaacgaa aacaattaat catggcaaag
       61 atcactgaag aaaactatgt ttctttagag gatttaatgc aattactcaa ctcctctgag
      121 tctactatcc gtagagatct aggagagttg gagcaagaag gacggctaca tcgtgttcat
      181 ggaggtgctg aactttttca ctctttacaa gaggaacttt cgaaccaaga aaagtctgtc
      241 aaaaacagtc atattaaaaa agctattgcg caaagagcct ctcagcttat ctatgacaac
      301 gatgtgatct ttattgatgc tgggacaacg actgaatttt tattaccttt tttacaagct
      361 aaaaatttaa ctgtagttac taattctatt catcatgctg ctagattagt tgaactctct
      421 attgagacga ttattgtagg gggttatgtc aaacaaacga ccgatgccag tattggtaac
      481 gtagctttgg aacagattag gcagatgaat tttgacaagg catttcttgg aatgaatggt
      541 gttgatgatt cttacctgac gactcctgat atggaagaag cagttattaa aaaagcggtt
      601 ctgtcaaatg caaaattagc ttacatttta gtagatggca ctaaaattgg tcaggtatcg
      661 tttgtaaaag tagctcctat taatgatgtg actattatta cattaggagg atcagcaagt
      721 attcttaaac aaataaagga aaaggcaaag gtgattgaat tatgatttat accgtgacct
      781 taaacccttc tattgacttt attgtcagaa ttgaccaaat aaatcttggg tcagtgaatc
      841 gcatggcgag tgatgataag tttgctggag gtaaaggcat taatgtgagt cgcatcttgc
      901 aacgtttaga cattgctagc acggcgacag ggttcttggg tggttttaca ggacgtttta
      961 tcgaagaaag tttgagtgca gaaggcgtta aaactgattt tgtaaaaggt gatcaagata
     1021 ctcgaatcaa tgttaaaatc aagtcacaag aagagaccga attaaatggt caaggaccta
     1081 tcattagtca ggaacaactg gaggatttga aaactaagct ttcccagcta acagcagagg
     1141 atacagttgt ctttgcaggt tcagcgccag ctaatcttgg caatgctgtt tataaggaat
     1201 tacttccttt agttaggcaa agcggtgctc aggtggtttg tgattttgaa ggacagactt
     1261 taatagatgc gcttgcatat aatcctctgt tggttaaacc taataatcat gaactagaag
     1321 ctatttttgg tacgattctg accagtcttg atgatgttga aacctatgcc cgtcgtcttt
     1381 tagagatggg tgctcaaaac gtcatcattt caatggctgg tgatggtgct ttgctggtta
     1441 ctaaagaagc gacttatttt gctaaaccga ttaagggaga agttaaaaat tctgtcggtg
     1501 ctggtgattc gatggttgct ggctttacag gcgaatttat gaagagtcaa aatccaatag
     1561 aagccttaaa atggggcgtg gcttgtggta cagcgacggc tttctctgat gacttggcga
     1621 caattgcatt tattaaggaa acatatcata aagttgaggt agaaaaacga tgaaaattca
     1681 agatttattg agaaaagata ttatgattct cgatttacag gctatttcta aagaagttgc
     1741 cattgacgag atgattacta aattagttga aaaagatatt gtacatgatt ttgatgtctt
     1801 taaaaagagt atcatgacac gtgaagaaca aacatcaaca gggcttggtg atgggattgc
     1861 catgcctcat tctaaaaata ttgtagtaga taaaccagcg gtcttgtttg cgaaatcaaa
     1921 taaaggtgtg gattacaagg ctttagatgg tcaaccaacg gatctcttct ttatgattgc
     1981 tgcgcctcaa ggagcaaatg atactcactt ggctgcacta gcagaattat cacaatacct
     2041 tttgaaagac ggctttgctg ataaacttcg tgctgcagcg acaccagaag cagtcattgc
     2101 tgtttttgat gaagcgtcaa cagctaaaga agaagtggtt gctccaacaa gtggtcaaga
     2161 ctttatcgtt gctgttacag cttgtccgac aggaattgct cacacttata tggcagaaga
     2221 ggctttgaaa aaacaagctg cagaaatggg agtagctatt aaagttgaaa caaacggtgc
     2281 ttctggtgtg gctaatcgtt taaccgctga agatattcag agagctaaag gagttattgt
     2341 tgcagctgat aaagcggttg aaatggaccg ttttgatggt aaacaattca ttgctcgccc
     2401 tgttgcagat ggtatcaaga aaagtcagga attgatttct ttgattttaa acaatgaagg
     2461 aaacacttat catgctaaaa atggaaaatc tgaaacagca gtatcaactg agaaaacaag
     2521 tttaggcggt gctttctata aacacttgat gggcggtgtc tcacaaatgt tgccatttgt
     2581 tattggtggc gggattatga ttgctctagc atttttattg gataacatgc ttggtgtgcc
     2641 aaatgatcag cttggaagtc ttggatccta tcatgaaata gcagctattt ttatgaacat
     2701 tggtggagca gccttttcct tcatgttacc agtactagca ggttatatcg cttattctat
     2761 tgctgaaaaa ccgggcttag tagctggttt tgtggcaggt gccattgcct caaatggtct
     2821 tgcttttggt aaggtaccat ttgcagcagg aggagaagtg agcttgggct taacgggcgt
     2881 gccatcaggt ttccttgggg cgcttgtggg tggtttcctt gccggtggtg ttattcttgc
     2941 ccttcgtaaa ttgttggcag gcctaccacg ttctctagaa ggggttaaat ctatcctcct
     3001 ttacccatta cttggcgtcc ttgtcactgg tttcttgatg ctttttgtca atattccaat
     3061 ggcagctatt aacacagccc ttaatgattt cttacaaggt ctttcaggaa gctctgctgt
     3121 ccttatggga cttcttgttg gtggaatgat ggctgttgac atgggtggtc ctgttaataa
     3181 ggcagcttat gtttttggta caggaacttt agcagctact gtggcaaatg gtggttcggt
     3241 cgttatggcc gctgttatgg caggtggtat ggtacctcct cttgctgttt ttgtagccac
     3301 tctcttgttt aaagataaat ttaccaaaga agaacgtgaa tcaggcttga caaatattgt
     3361 tatgggactt tcattcatca ccgaaggagc aattccgttt ggtgcagctg acccagcacg
     3421 tgcgattcct agctttatcg caggttctgc cttgacagga gctcttgttg gtttggctgg
     3481 tattaaatta atggcgccac atggtggtat cttcgtaatc gctttaacaa gcaatccaat
     3541 cttatatctt gtctttgttg tgattggtgc ccttgtatca ggtatcttat ttggcgctct
     3601 tcgcaaaaaa gcctaaaagg taaagaactt ttttcttact aaaactagaa tctgtcaagg
     3661 ttctagtttt ttgctatact agagttaaag gataagaaat gaggaccttt gaaggtgaaa
     3721 aaaaggagaa gaagggctaa atcatcagta aatcgacttg tcttagggtt agtattactt
     3781 aatctgattg ttagtatgtg gacactaaaa ttgggaaacc agcgattagc tccgtatgcg
     3841 gatcacgaaa ctctgacatt tgtcaggaag attagtcatg ctgctcaatc agtcgctcaa
     3901 aagaaacagt tatacagttc ggtgatgatg gctcaggcca ttttagaatc caataatggt
     3961 aagtcacaac taagtcaaaa accttattat aattttttcg ggattaaggg gagctataaa
     4021 gaacggtcag tcatttttcc aactttagaa gacgatggac aagggaatct ttatcaaatt
     4081 gatgctgctt ttcgttccta tgggagcctg acagcttgtt ttttagatta cgcaagagtt
     4141 ttgaatgatc cactttatga caaaacccac aaaaagtttt ggtctcatta tcaagatgct
     4201 actgcaacct taacaggcac ttacgccact gatacaactt accataccaa attaaatgaa
     4261 ttgattgaat ggtatcaact cactaatttt gatggtctaa tgaaatagtt atccacaatt
     4321 ttaaaaaaaa tcagaagaaa tatgtcgatt tcaagacaaa agttatcaat ctcattaaat
     4381 tatctgtgga aaagttaatt taaacgttcg tgtgctataa tagaaacata gaaaatgaat
     4441 aaaaaaggat atatgaataa tgacaaaaaa gaaaggtaag cttgtactta tcagtctttt
     4501 tgttctagca gcttgtttag gagcttatag tgcaatgaga caatctcata aaacttcaaa
     4561 cgtgtcagct gagactatcg ccagttcttc aacccgacat tttattgatg aaattggtcc
     4621 aactgctagt actattggtc aagaacgtga tctttatgcg tctgttatga tagcacaagc
     4681 gattttagaa tcaagtaatg gtaaatcaag tctaagtcaa gcaccttatt ataatttttt
     4741 cggtattaag ggtgcctata acggttcttc tgtgacgatg tcaacttggg aagatgatgg
     4801 taatggcaat acctatacga ttgatcaagc ctttagagct tatccaagta ttgcagactc
     4861 ccttaatgac tacgcggact tgctaagttc tagcacttat ataggtgcta gaaaatcaaa
     4921 cacgctatcg tatcaagatg ctacagcagc tctaactggc ttatacgcta cagacaccag
     4981 ttataactta aaactaaata atattattgc aacctatggt ttgacggctt atgatgttgc
     5041 taatagctca gctcaagaaa ctggtctagc aacttcgggt tatgtttgga atgaatatcg
     5101 tcgtaattac actgatgcgg agaccctagc agttgatgag gcttgggcta aacgcatgac
     5161 ttattaatgt aacactaaca acaatctgct tgcactgacc ccaaaaaagc tggatactct
     5221 attttaagta aaggatttag ttctgtattg tacagaacta aatcctttta gttttacttt
     5281 gatatgttta tcgttgtaat aatcaatgtc atttgtaatc gcttgttcta agtcttctag
     5341 tgatttatag ttattctcat aaccatagaa catttctgac tttaagatgc caaagaaaga
     5401 ttccatcatg ccattgtcag gactgtttct tttacgtgac atagacggac gaattccttt
     5461 agagtttagg aaatgatgat aatagttgtg ttgatattgc caaccttgat cactctatca
     5521 tatagttccg tcatagcatt tatttggaga tgcctttttc cattattggt ttaatgtgat
     5581 ttaagcaagg ttattagcta aatttaatgc cagacaaaaa taccccaatt attagatttt
     5641 ttgtctaact tttggggcgc aattcaatct gagcagtttt agatttggta tcaatgttat
     5701 tataggtcaa ttgatcatat ttatccaaag cttttagctt atttagtcca aagataaata
     5761 tcaaaatggc tgaaatcttt catatttata gtcttattgt ctttatattt tttaaagaca
     5821 tcagatctgg tgctattggg ttttgcgtca tataaattga ttttttcatg tttcctattt
     5881 ttactgtgaa tttctaaact cccccttata taaggagact tagtcaaata aatttctttt
     5941 gattccatca aaaattttct tattttaaaa tcgaactctt gaatcgtaac aatatcctta
     6001 tcgattttta taggatttat taatgttttt gctgttgccc atctataaaa aaattccctg
     6061 caatagtatt agtccttaga ataccatcat ctgttgaagg taatctttct tattgatacg
     6121 ctttaattgg tctgattcca actatcttgc cctgttgaaa gtgtaaataa ccctagtact
     6181 tgagcaccaa tattatcttc ttttatttct ttagcagaaa tagctacttt tccagcggaa
     6241 ttaacaccaa caaagtattt cttcatacca atagatgcat tactatcaga gtctgttaca
     6301 taaatagctt taaggttccc gttagaatca aagtcagctc cccacaggtt tataacatgg
     6361 ttgatgcgta cgttagcgta ggtgtgtgat aggcctagag ccttgccttc ggttaactct
     6421 ttcttaatga gatcactgat ttctttgaga tttttttctt taaaatcatg acgacttgtc
     6481 aatagcttac tttgatcacc tcttgtaaat acggcgtcaa aaataccacc tcggggatct
     6541 ttactacctt cttttactgg cgttggaccg tggttagtta gactaaggcg gtagccgtta
     6601 atgaacatat caattacatg atcagggaaa actcctaggt gtttagtaga tagataaggg
     6661 aaagcttttt ctttaaaata ttcaaataat ttactatcta gctggtggtt tttagtgtcg
     6721 atagcttctt ttacgtcaaa catctgttcg ccattgaagt ttattttttg cttttctgga
     6781 tgctcttcca aataacgttt aatttggtct ttgttttgat cgaaccacca gtgaagcata
     6841 ttccctgctg tggcagcccc gcaaagaaga tcgtcttttc cattgaatgt tttggtaata
     6901 tcataccatc cttggttagc aacataagga gcgtgaaaaa catcttcacc ttgagtgaag
     6961 tttgctggag gagtaactcc tttggtccaa acggaagtaa cgtgataagg tgttacttcc
     7021 gaatatctaa tctcttgatt agcagaaaaa ctatctgcta taacaccacg atctaccgat
     7081 agaacaaata aagtcactgc tgccaatact gcagctgaag ttgaatagca tctttttctc
     7141 ataagaatac ctttttctat ataattttat gataaataaa ttatataata tagacatata
     7201 ttattgcaag ttcttaaaat aatatttaat ttttttaaat aatttttaat aaaattaaac
     7261 atgcgattgc aatggagaca gtacaagaga tacagtagtg gttgtgctta aaaatgaacg
     7321 gttttttgat gatatgttgc tgcatgagga agtgagcaat aggagagctg tgatagaaga
     7381 aagaggggaa gaagcgttga tgaaattaga caaataaaaa aagacctcat ccagaagagg
     7441 tcgtgtataa ctggggacga taggttcaat tgataaaaaa tcttgttagc ttacgatcta
     7501 tgtggttttg aatgccttta actcaacatc gttaatggag tttgagataa aaaaataaat
     7561 ccaatagtct ggtactttcc tattttttgt ctgttaaaac gtttttattt tataatggat
     7621 aaaagaagaa gggcggagcg atgattaagc cctatgggtt taagtatggg ttagttggag
     7681 aggttttgcg gcggattgaa cgcctagggt ttacgtttga gcgattagag ctaagacaag
     7741 ctagttcgaa atacttggct aagcatgatg aggccttggt gataaacctt tttatcctgg
     7801 acttaaaact tacctgacca gtggttctgt tttaattgag gtgcagtaca agaccactaa
     7861 cgggtgtttt tttggtataa tgtcagtata aggacgacta aatataaata ggtgaaaaaa
     7921 tagatatctg ttcgagagat agcactgttt aaaacgttat gcgaaaatag tagtttaggg
     7981 gctactttaa taattttcaa atctatgcta taatggatca tattgatacc aaggagaata
     8041 aaaaatgcaa ttagttcgtg aaaaagaatt tgtcaaccag taccattatg atgctagaaa
     8101 tttagagtgg gaaaaagaaa acggaacacc agagaccaat tttgaagtga cttttcagtt
     8161 gattgataaa gatgagcagc aaaaagaaac agtaattgta tctgtattgc aatttgttat
     8221 tgtcaaagaa gaatttgtta ttagtggggt catctcacaa atggttcgta ttttagatcg
     8281 tttagtggat aaaccaagcg aatttacgca agaggaagtt gaatccttag ctgctccttt
     8341 gctagatatg gttaagcgat tgacttatga agtcacagaa attgccttgg atcgtccagg
     8401 tattcatttg gagtttaaaa attaatgaaa ttagcagtaa ttactgacag tacagcaaca
     8461 ctaccaacag atctgaaaca agataaagct atttttagcc ttgatatacc agttatcatt
     8521 gacgatgaga cctattttga aggtcgaaat ttgagtatag atgattttta tcaaaagatg
     8581 gctgactccc aaaatcttcc caagacaagt cagccaagtt tatctgaact agataatctt
     8641 ttaggacttt tatcttctaa aggttataca catgttattg gcttgttctt agctggagga
     8701 atctcaggct tttggcaaaa tattcaattt ttagctgaag aacatcctga gattgaaatg
     8761 gcatttccag acagtaagat cacatctgct cctttaggta gtatggtaaa aaatgtgcta
     8821 gattggtcac gtcaaggaat gacatttcaa gctattttaa acaagctgca agaacagatt
     8881 gatgggacga cagcctttat tatggttgat gaccttaatc atctggttaa aggcggacgc
     8941 ctgtcaaatg ggtctgctct tcttggaaat cttttgagta ttaaacctat tttacgcttt
     9001 gatgaagagg gaaaaatcgt tgtttatgaa aaagtgagaa cagaaaagaa agccatgaaa
     9061 cgcttggttg agattttaaa tgacttgata gcagacggtc agtataatgt gtttattatt
     9121 cactcaaaag cacaagacaa agctgattat ttgaaacgac tcttacaaga cagtggttat
     9181 caatatgaca ttgaagaggt tcattttgga gcggtgattg ctactcattt aggagaagga
     9241 gccattgcat ttggcgtaac accgaggctt taattgtcga ttagaaaaaa tagttaatgg
     9301 caagaatcac taaaacaata acaaaatgtg atagaaccca attagcctaa tcacacttta
     9361 gattgggcta gttggatgat aggttagaaa acaacgtatg aaattaatga caatgccttc
     9421 tgagtttcag aaggctttac ccatattgac taaaataaaa gaagctggtt atgaagccta
     9481 ttttgtggga ggaagcgtca gagatgtttt actcgagcgt cccattcatg atgtagatat
     9541 tgcaactagt tcctatcctg aagagactaa agcgattttt aacagaactg tcgatgttgg
     9601 cattgaacat ggtacagtgc tcgtgcttga aaatggcggt gagtatgaaa ttacaacctt
     9661 taggacagaa gatatctatg ttgattatcg ccgtcctagt caggtttctt ttgtgcgctc
     9721 tttagaggaa gacttaaaac gaagagactt taccgtcaat gccttggcct tggatgaaaa
     9781 tggtcaagtt attgataaat ttagaggact cattgattta aagcaaaaac ggttacgagc
     9841 agtgggtaaa gcagaggaac gttttgaaga agatgcacta cgcattatga gaggctttcg
     9901 atttgcggcg agtctggatt ttgacattga agctataact tttgaagcta tgaggagcca
     9961 ttcacctcta ttggaaaaga tttctgtgga acgttctttt actgaatttg ataaattatt
    10021 gatggcaccg cactggcgaa aagggatttc tgccatgatt gcttgtcagg cttacgacta
    10081 tttaccaggc ttgaagcagc aggaagcagg cttgaatcat ctgatagttt ctttgaaaga
    10141 taactttacc tttagtgatt atcaccaagc ttgggcttat gtgatgatta gtttagccat
    10201 tgaggatcct aaaagcttcc taaaagcatg gaagacttca aatgattttc agcgttatgt
    10261 cacaaagttg attgctcttt atagaattcg tcaggaaaga tcttttgaaa aattggatat
    10321 ttaccagtac ggcaagaaaa tggcgagtct agtggaagac ctccgaaaag ctcaaagctt
    10381 atccgttgac atggatcgta ttaatacttt agatcaggca ctggttattc atgacaaaca
    10441 cgatatcgtc cttaatggtt ctcacctgat taaggatttt gggatgaaat caggtcctca
    10501 gctagggctt atgcttgaga aagttgaatt agcgattgta gaggggcgcc tagataatga
    10561 tttcactaca attgaagcat ttgttagaga ggaattagca acatgagcca ttttttggtg
    10621 gagaaattaa caaaaacggt gggagataag accgtctttc aagatatttc ctttattatt
    10681 catgactttg accgtattgg gattattggg gttaatggaa caggaaaaac aactctttta
    10741 gatgtgttgt cgggaaggct tggttttgac ggagatcatt caccattttc taaagccaat
    10801 gattacaaaa tcgcttactt aacacaagac cctgaattta acgatgcagc ttctgtttta
    10861 gatacggtat tatcagctga tgttaaagct attcaactga ttcgtcagta cgaactattg
    10921 atggcgaatt atactgagga taaacaagaa agcttagagt ccctcatgtc tgaaatggat
    10981 cgattagatg cttggtctat tgaaagtgat gtcaaaacag tcctatcaaa attaggcatc
    11041 acggatttgg aacaaaaagt gggagaccta tcaggtggta tgagaagacg tgtccagtta
    11101 gctcaagtgt tgctaggagc tgctgactta ctcttgttgg atgagccgac caaccatctc
    11161 gatattgaca ccatcgcttg gttaacaacc tatctcaaga cagctaaaaa aaccgtcctt
    11221 tttattaccc atgaccgtta tttccttgat catgtggcta cccgtatttt tgaattggat
    11281 aaagcgggac tgacagaata tcaaggcaat taccaagact atgtgcgctt aaaagcagaa
    11341 caagacgaac gagatgctgc taatttacac aagaagaagc aactctataa acaagaatta
    11401 gcctggatga ggacgcaacc acaggcgcgt gcaaccaaac agcaggctag aatcaatcgt
    11461 ttcagtgact tgaaaaaaga agttcaccaa gacagttctg cggataaatt ggagatgact
    11521 ttcgaaacga gccgaattgg gaagaaggtg attcactttg aagacctttc ttttgcttat
    11581 ggcgaccgac agttgattaa ggattttaac ttgattattc aaaataaaga tcgtattgga
    11641 attgttggag ataacggcgt cggaaaatct accctgttaa atatcattaa cggtgatctc
    11701 aaaccaactt ctgggaagct tgatattgga gatactattc gtgtaggtta tttctctcag
    11761 cagctcaaag atatggatga gaccaaacgg gtcattaatt accttcaaga agtggctgat
    11821 gaggttaaaa caagtgtggg aacaacgagt atcagtgagc ttttagaaca atttcttttt
    11881 ccgagatcaa gtcatggcac gctgattgct aaattatctg gtggggagaa aaaacggctc
    11941 tacttgctaa aactgctcat tgaaaagcca aatgttcttc tccttgatga gccaacaaat
    12001 gatttagaca ttgccacctt gaaggtctta gaaaactttt tagctaactt tgcaggacca
    12061 gtcattacgg ttagtcacga tcgttatttc ctagacaaag tagctactaa gattttagcc
    12121 tttgaagaag gcgatattcg tgttttttat ggcaattaca gtgattacct tgatgaaaaa
    12181 gtttttgaaa aagaaacagt tgaggcagac ttagctaaaa caacagtcac tgaagaagtg
    12241 ccacttcctc aaaaagagga aagaaagcgc atgtcctacc ttgaaaaaca agaatgggct
    12301 cagatagaag ataaaatagc aactattgag gctaatattg aagaaattga aaaccaaatg
    12361 ttaactgtag ttagtgatta tggccagtta gctcaattac aaaaggaact cgatcagcgc
    12421 aataatgatt tattattggc gtatgaacgg tttgagtatt tgagtggact agacatataa
    12481 gtatactatg gtaatgttat gtttataata aacaagtgat aatagaaaag aagggctctt
    12541 gcactgagcc ccaaaagttg gctactctat ttgaagtaaa ggatttagtt ctgtgttgta
    12601 gaggactaag tccttttcgt tttattttaa tacggttatt gttgcaataa tcgataataa
    12661 tagtaggtag aacgagtcaa tttagccgtt cttaaaagaa aatttaatca gaactcgtct
    12721 ttgtccattc tttataatgg ttttttgtct tcttctttgc agagatgctt ctttcaaacg
    12781 gagttccctc ggttttttta gcgctaaata tctagcttat cttcatagct taatgtcata
    12841 caaaaacacc ccaaacgtta gattttttta tctaacgttt ggggtgtagt ttacattatg
    12901 gcgcttcttt tctattatta cgtgaggaaa aatcaagtaa aaaagttaag tcaactgaaa
    12961 aacttgacag aaatattcag aaaatttata atactaacta ttaacaacat atcagctatt
    13021 aaagcatttc aaacagcagg tgttttgttt ggacctatca aggctgcaaa tgcaagagaa
    13081 agcagtatct ggtttgaaaa tctcacaaag caataactat ctctcttaga catttgaaga
    13141 agcagacagt aaattcgata atattgtgat gagaacttat taacaatctg ctgatgcagg
    13201 tcaattttta tttggtactc atattgcaga atttcataaa gttgcccaag atatcttgaa
    13261 ataaggaatc acctgatgtt ttaaacagat gatactaagt ctatcatata gtgataatag
    13321 tccattgaac atgtagttta tgaattaaaa agaaggttta aggagataag aatgattaga
    13381 gaaatcataa cagatcattt tttattacag caaaaagcgc aagtcgccaa gaaagaagat
    13441 ctatggattg gccaagattt acaagatacc ttagcctttt atagacagga atgtcttggg
    13501 atggctgcca atatgattgg tgaacaaaag cgcattgtta ttgtgagtat gggatttatt
    13561 gatttggtta tgtttaatcc tgtgatggtt tctaaaaagg gaatttacca aactaaagaa
    13621 tcttgtttgt cgttatctgg ctatcgcaaa acacagcggt atgataagat tactgttgag
    13681 tatttggacc ataattggcg accaaagcga ttaagcttaa caggcttaac tgctcaaata
    13741 tgccagcacg aattagatca tctagaaggt attttaattt aacaaaaaac ctagagtagg
    13801 acgctttagg tttttttggc aaagatgcct gattatataa gggtgatcga ttactagtaa
    13861 acgctaggat ttcctttttt taataaaagc gtttagtcca cctaagctta tcaaggcaag
    13921 gattgtcata ataggagaca ttttataatt gtcccctgtt attggaagag tggaactaga
    13981 gatagtattt ttgtttgttg ttgtttcttt tttgccaagg ctgttattag tgttttcagt
    14041 agaagtcaaa aggtctgaaa tgacttcact agacactgta ttgccatcac gatttctaaa
    14101 aaccttacta atgatactgt gtttaccagc actattaact tttgtcgaac tttcaaggtt
    14161 tgaagttaca taatttttaa ccccttttat agtagcatta acagttttac ctgatgcttc
    14221 taaatttgtg atatatgtga tgaaagcttc agtatctgtg ttaatagctc cgattaattt
    14281 agctttttta aatgctgaaa agccatcacc accaccataa agaaagtcgt tgacaacaac
    14341 ggtgtaagta gttgttaagt taatttcttc accattgtct ttataaacct taactatctt
    14401 gaagggggta tcagagttct taggatcatt atctgtataa gtgtatgtta aacctgacat
    14461 ttgaagaaaa taggtctggt tttcatcgta ttgctgattt aggacatcgt aaatgtgttg
    14521 accagtcatt tgaatgactt gaaggatatt accaaatggt tgtacagcct gtgcagctcc
    14581 ccaggtgatg gtccggtcat ttttgacaac taggtcactt cgaataccac cattattggt
    14641 catagcaaag tcaacagttg gaaaagtttt cttagcaata gtaagctgag ccgttgttgc
    14701 taagttaccg acaggagatt ctttatcaat attttctgtt ttagaaatag ttgaagaatt
    14761 agttgcagtt ccgatttttc gttcagtaac tgttttaaca atatcattag catgatttat
    14821 tatagctttg atatctgaat tttctgtttt gatacctggt gctacagcaa caacatttgc
    14881 tgatggagtt ttaataaaat cattggtatc agtatctagc gtaccacgga catctgcata
    14941 agcttttcct tgagagaggg cttgaacgat acgtgtttta ccgatagttc cattagtgta
    15001 ttgatgatta tgtcctgcaa aaataatatc aatgctatgt tcgggataga tttggttcac
    15061 tttttccata accgtagcca tttcatgatc aacaacacca tctttacttg ttgcaggaac
    15121 atgagctaaa accacaatag catgaacatg ttgttcttgt agttctttag catatttggc
    15181 aatggtttca gctacatcta aaaattgata gtgttcatag ttttgcttta aaacgagatt
    15241 tggaatctct gtagtcacaa caccaatgaa gccaatctta acgattttgt cattaatggc
    15301 tatgtctttt atagcataag gtttccaacc ataggggata tccttggttt ttttatcaat
    15361 aacattagca atgacgatgg tttgatgcga agcttcgtgc tcatattgtt tggtgatatc
    15421 attaattgtt gattcaggat caggcgcttg acctgtcatg atacggttaa attcatctag
    15481 tccttcgtca aattcatgat taccaagagt gccatattca aatttcattt tgttaaagac
    15541 tttgacagta ggctcatctt gtaaaagtgc agagttagca ggactggctc cgaccatatc
    15601 tccagcttga acacgtatac ttgttccgtc ttgatttgct tgcttgaagt ctatctcagc
    15661 gtcatccata taagcaccta attgagcagc cgtcccagca tttggtattt taccacttgg
    15721 tgtgtaagct gttccggtat tatcaagagc gccgtgaaaa tcattgacgc caaggaattg
    15781 cacatcaact tgatctgctt gaacatctgt aactaataga gtaaaactag tcaggatact
    15841 caatacacta ctttttaaaa taaaatattt tttcataaaa tctcctaata agttaacgta
    15901 atcgttatag atcaagttta ctatgatttt gtttgtaatt caatggtatt tttaaaaaat
    15961 aacgtacaaa aaatatatga aagcgattta aaaacaaacg atacagatca tttgaagtta
    16021 tatagttaga aataaagata accgatcatt gcagagattt aagcatttgt tgagaaaatt
    16081 tgttataata agcgtatgaa agaaagacta gaacattatt ctaccagctc tatatatagc
    16141 ggatttgaag tgtacttgcc gttggtacta cagacaataa cagatgtgat tattgctgag
    16201 aatatcaaaa gcaaaaaaga aacggggttt aaactatacg aacactttac atcccgtatt
    16261 aaatcggaag cttcgatgat tgaaaaatgt caacgcaaac agcttcctct aacaagcaaa
    16321 tctgcgttaa aaatcattaa agatagtatc ggtattcgca ttatttgtgg ttttattgat
    16381 gatatttatc ggatggtaga cttgctcaaa agcattcctg gtatgtcagt taacactgaa
    16441 aaagattata ttttaaatgc caagcctaat ggctatagat catatcatct cattttggaa
    16501 ttagaaacac attttccaga tattttaggg gaaaaaaaag gatgttattt tatagaagtg
    16561 cagttgcgaa ccattgctca agactcttgg gctagcttgg aacatcaaat gaagtacaaa
    16621 catcaagttg ctaatgcaga aatgattaca agagagttaa agcgttgtgc agacgagttg
    16681 gcatcttgtg atgttaccat gcaaaccatt cgtcaattga ttcaagaaac gacggaggaa
    16741 gagtaaccat gaaaattttg ttagctgaag acgaatggca gatgtctaat gttttgacaa
    16801 ctgccatgac tcatcaaggt tatgacgttg atgtggtttt taacggtcaa gaggcaattg
    16861 ataaagccaa agacaatgca tatgatatta tgattttaga tatcatgatg ccgattaagt
    16921 ctggcattga ggctttaaag gagattcgcg cttcaggaaa ttgctcacat attattatgc
    16981 tgacggctat ggcagaaatt aatgaccgtg ttaccggact agatgcggga gctgatgatt
    17041 atctgactaa acctttctca ttaaaagaac ttttagctag attaaggtcg atggaaagac
    17101 gagtagaaag ttttactcct caggtattac aatttgctgg tgtcacatta aatattaatg
    17161 agcaagaatt gagtgccggt aatgctatac gattagcttc taaagaaggt aaattaatgg
    17221 cctttttaat gttaaatcaa ggaaagtact tggatactaa aacgctttac caacatgttt
    17281 ggtcagacca agaagattat gatacttcta ttgtttgggt ttatatttct tatcttcgtc
    17341 aaaaattatt agctattcaa gcaaatgtca ttattgcagg tgataaagat actagctatt
    17401 gtttattaga aaaataggag gtgacatgtt taatcgtatc cgcattcgtt ttatcatgat
    17461 tgcttctatt gccattttta ttattttaag ttcaattgtt ggtattatta acacggcacg
    17521 ctgttaccaa agtcaacaag aaattaaccg tattttacat ttaatttcct caaataaagg
    17581 taaattacct ggcactacgg aaagctctaa acgacttgga acgaaactgt ctgaagatag
    17641 cctaagccag tttcggtatt atagtgtcat ttttaatgct aatggacatc tactttcttc
    17701 taatactgct aatatttcag ctttagatag agaagaagcc caatattttg ctagactttt
    17761 tgctaagtct ggggaagaaa aaggcagtta ccgtcaccaa gatagtgttt attcgtactt
    17821 gattactcag ctgccaaatg aagaaaaact ggttgtaatt ttagatacta ccttttattt
    17881 tcgtagtgta ggagatttat tagctgtttc agtgatgttg gcctttggag gatttatctt
    17941 ttttgttgtt ttagtgagtc ttttttccgg tatggtcatc aaaccttttg tccaaaatta
    18001 tgagaagcag cgtcgcttta ttactaatgc aggccacgag ttaaaaacac cactagccat
    18061 tatctcagcc aataatgaat tggtcgaatt aatgactgga gaatcagaat ggaccaagag
    18121 tacaagtgat caggtgaagc gattgacagg cttgattaat caaatgatta ctttggctcg
    18181 tttggaggaa cagccagatg tggtattaca tatggtagac ttttcagcta ttgctcaaga
    18241 tgcagctgaa gattttaaga gtctggtttt gaaagatggt aaacgttttg atttgacgat
    18301 tcaaccgaat attatgatta aagcggagga aaagtcattg tttgaacttg tgacaatttt
    18361 agttgataat gccaataaat attgtgatcc taaaggcttg gtcaaggtat ctttaaccac
    18421 tattggaaga agacgaaaac gagcgaaatt agaagtttct aatacctatt tggaaggaaa
    18481 atccattgat tacagccgct tctttgaacg cttttatcgc gaagacgaat cccataatag
    18541 caaagaaaaa ggttatggaa ttggtttatc tatggcagaa agtatggtta agttatttaa
    18601 aggaacgata actgtaaatt ataaaaacga tgctattgtt tttacagtgg tgatttgact
    18661 taaacatttt tcagtacctt tagctagtaa taatgtctag gtaaaggtaa taaacgatgc
    18721 ttaaccagcc catgaggctg gtttttaacg tttaatttag tagaagagtg attaaagaag
    18781 gtagtttgaa ataagaaaat ttttgttatg atcttaaaaa gagtagatag tctttattgt
    18841 taatttcagt gaagaaatga ttttaaaaag atatatcatc gcattttcta atcatttagt
    18901 gtaaaatagt aaggtaaaag tttagaagaa ttagtaatga aaagacaaaa aatgaacgaa
    18961 aacattggat atggtaaggc acacagtaag atcattttga taggtgagca tgctgttgtg
    19021 tatggctacc cagctattgc tttgccttta acagatattg aggtggtttg tcatattttt
    19081 ccagctgata agccattggt ctttgatttt tatgatactc tatcaacagc catttatgct
    19141 tccttggatt atttgcagcg actacaagaa ccaattgctt atgagattgt ttcacaagtg
    19201 ccacaaaagc gtggtatggg gtcttcggca gccgtttcta ttgcagctat tagagccgtt
    19261 ttttcttatt gtcaagaacc cctctcggat gatttgttgg aaattttagt caacaaggca
    19321 gaaattattg cccacaccaa tcctagtggt ttagatgcca agacatgcct tagtgaccat
    19381 gccattaagt ttatccgaaa cattggcttt gaaactatcg aaatcgcctt aaatggttat
    19441 cttatcattg cagatacagg gattcacggt catacacgtg aggccgtcaa taaggtagca
    19501 cagtttgagg aaacgaattt gccctatctg gctaaactag gagctttgac acaagccctt
    19561 gaaagagcga ttaaccaaaa aaataaggtg gctatcggtc agctcatgac acaagcgcac
    19621 tctgctttaa aggccattgg cgttagcatc agtaaagctg accaacttgt ggaggctgcc
    19681 ctaagagcag gtgctttagg cgctaagatg acaggcggtg gcttgggtgg ctgtatgatt
    19741 gccctagcag ataccaaaga catggccgaa aaaatcagtc acagattaaa agaagaagga
    19801 gccgtaaaca cgtggatcca aatgttataa ccgtaacatc ctatgctaac attgctatta
    19861 tcaaatattg gggaaaagag aatcaagcta agatgattcc ttcgacctct agcatttctt
    19921 tgactttgga aaacatgttc accacaacca gcgtttcctt cttaccagat actgcaacca
    19981 gtgatcagtt ttacattaac ggtatcttgc aaaatgacga agaacatacc aaaatttctg
    20041 ctatcattga ccaatttcgc caacctggtc aggcttttgt aaagatggaa actcaaaata
    20101 atatgccaac agctgcaggt ttatcatcaa gttccagtgg cttatcagcc ttggttaaag
    20161 cctgtgacca attatttgac acccagctag atcagaaagc tttagctcaa aaggctaagt
    20221 tcgcctcagg atcatcttct cgttcttttt ttggcccagt cgctgcttgg gacaaagata
    20281 gtggtgctat ttacaaggtt gagactgact tgaaaatggc catgattatg ctggtcttaa
    20341 atgctgcgaa aaagccaatt tctagccgag agggcatgaa gttatgccgc gatacctcaa
    20401 ctacatttga tcaatgggta gaacaatcgg caatcgatta ccaacatatg cttacctatc
    20461 tcaaaactaa taattttgag aaagttggtc agttaacaga agctaatgcc ttggccatgc
    20521 atgccacgac aaagacagcc aatcctcctt tttcttacct aacaaaagag tcttaccagg
    20581 ctatggaggc tgtgaaagaa ctgcgtcaag aaggttttgc ttgttatttt accatggacg
    20641 caggtccaaa tgtgaaggtc ctatgtttag aaaaagactt ggctcaacta gcagaacgac
    20701 ttggcaagaa ctaccgtatt atcgtttcaa aaacaaagga tttaccagat gtctaattat
    20761 tgtgtgcaaa caggtgggaa actatacctc acaggcgaat atgctatctt aacaccagga
    20821 caaaaagcct taattcactt tattccattg atgatgacag cagaaattag cccagcagcc
    20881 catattcaat tagcttcaga tatgttttcc cataaagcgg gcatgacacc cgatgcctct
    20941 tatgcactga ttcaagcaac ggttaaaacc tttgctgatt atctaggaca gtcaattgac
    21001 caactggagc cattttccct aattataacg ggaaaaatgg agcgcgatgg caaaaaattt
    21061 ggcattggtt caagtggtag cgtcaccctc ttaaccttaa aggccttatc ggcctattat
    21121 cagattactt taaccccaga gttactcttt aaactagcgg cttatacctt gcttaagcaa
    21181 ggagataatg ggtctatggg ggatattgcc tgtatcgctt atcagacttt agtcgcctat
    21241 acctcctttg accgagaaca ggtcagtaat tggctgcaga ccatgccctt aaaaaaactt
    21301 ctcgtcaaag attggggtta ccatatccaa gtcattcaac cagccctgcc ttgtgacttt
    21361 ttggttggct ggactaaaat acctgctatt tcaaggcaga tgattcaaca agtgacagcg
    21421 agcattaccc cagctttctt aagaacaagt taccagctaa cgcaatcagc tatggtagct
    21481 ttgcaagaag gtcataagga agaactcaag aaaagtttag caggagcaag tcatctccta
    21541 aaagagattc atccagctat ctaccatcct aagctagtaa ccttggtagc tgcttgtcag
    21601 aagcaagatg ctgttgctaa atcttcaggt tctggtggtg gagattgtgg catcgcgctt
    21661 gcctttaatc aggatgctag agataccctt atttccaaat ggcaagaagc tgatatcgca
    21721 ttactttatc aagaaaggtg gggagagaat gactaaccgt aaagatgatc acatcaaata
    21781 tgctctcaag taccaatcgc cttataatgc ttttgatgac atagaactca tacaccattc
    21841 cttacctagc tatgatttgt ctgatattga tctcagtact cattttgctg ggcaagactt
    21901 cgactttccc ttttacatca atgccatgac aggaggaagt caaaaaggca aagctgtcaa
    21961 tgaaaaattg gccaaagtag cagcagcaac agggattgtc atggtgacag ggtcttatag
    22021 cgctgcttta aaaaatccta acgacgattc ctatcgttta catgaggtgg cagataactt
    22081 gaaactagcc acgaatattg gtctagataa acctgtggcg ctaggacaac aaacggttca
    22141 agaaatgcag cccctctttt tacaggttca tgtgaatgtg atgcaagagt tgctgatgcc
    22201 agagggtgag cgcgtctttc atacctggaa aaaacacctc gctgaatacg ctagtcaaat
    22261 accagttcct gtcattctca aagaagttgg ttttggcatg gatgtcaata gtatcaagct
    22321 agcacatgac ctaggcattc aaacctttga tatttcaggt agaggaggaa cttcatttgc
    22381 ttacattgaa aatcaaagag ggggagaccg ctcttactta aacgattggg gacaaaccac
    22441 tgttcagtgc ttactgaatg cacaaggact gatggaccaa gtggaaatct tagcttcggg
    22501 tggtgtcaga caccccttgg acatgattaa gtgttttgtc ttaggagcac gtgcagtggg
    22561 actctcacgc accgttttag aattggtcga aaaataccca accgagcgtg tgattgctat
    22621 cgttaatggc tggaaagaag aattaaaaat cattatgtgt gctcttgact gtaaaactat
    22681 taaagaatta aagggagtcg actacttact atatggacgc ttgcagcagg tcaattaggc
    22741 ttcatcacct ctacaatagt gtcacctact acaaagatga tagagctttt ttagaacata
    22801 atataaaata tttataaata cctcatcaaa ctcagaatag agtagatgag taaatagagt
    22861 atgttatgga gactatttct aagacttgta tgtatagaaa taaagattaa acacccatgt
    22921 aaaccaattg tttacatggg tgtttgcctt atattagttg tttaaatcta agactgtctt
    22981 agctgggata agtaaaaatg tgctttttct agatttattg gtttatcagc tagtaaagca
    23041 ttaactaaag gagcaatttc gtcttgggtt gcccccgcca aaagagctaa tgatttcgca
    23101 tgtagtttca tgtgaccagc ttggatgcca gatgaggtca gagcttttag tgcagcaaag
    23161 ttttgagcta accccacaga tgcaatcaat tgggctaatg ttttggcatc aggttgatta
    23221 agaagatcat gtgcgataga aacagtaggg ttaagcccga tagatccccc cttactagca
    23281 ataggcatag ggagggtcat ttggccaagc agaacttgtt tatcttggtc aaaatgccac
    23341 tgactaagtc cttgatagct accatttctt gaggcataag catgggcccc tgcttcaata
    23401 gcacgccagt catttcctgt ggctattacc actgcatcaa tgccattaaa aataccttta
    23461 ttatgagtag tagcccggta aggatctact tgagctagtc ggctggctag ctctattttt
    23521 tgagctaact gtagggattt tgttttatcg tgatctaaaa ggcgcacggg aatctcacaa
    23581 ctagtagtaa caagcgactc tgttgcgtaa ttagataaaa tcgccattag acaatgcccc
    23641 ttagacagtc ttgttaaatc aggaacaaga gcttccatca tagtattgac catatttgct
    23701 cccatagctt cttgggtatc aacagtcaga tagaaaatca aaaattctcc tttttcttcc
    23761 aaatgaatgg ttctagcgcc tccacctctt ttaacaatgg aaggataagc tttatttgcc
    23821 aatgcaatta gcttttttgt tttatgaagg atggcggctt tagcgttatc tatttggtcg
    23881 atatcgtaaa gaacaatttg accaatcatt tgtcggttta gggtttgagc tttaaaacca
    23941 cctgagcgtt tgattagttt tgctgcgaaa gatgctgcag caacaacaga aggttcttcc
    24001 gtgacaaaag gcatctgata agttgaaccg ttgacaagaa aatcaggagc tatgctaaag
    24061 ggcaaagcca atcgtcctaa gacattttca gtcatttgat tagctgtttg gataggcaaa
    24121 agaacgtctg ttttgagttg atttaagttt tcagcattaa gtagtttaaa tttttcgata
    24181 agttggaggc gttcttcgaa tgttttcttt gaaaaaccgc tccagttaag attagttttt
    24241 gtcattggta tgatagatcc ttcgatgctc cttgatggct gttagagcaa attttccagt
    24301 taagtaaatg tcaaaattgg cattaccatt atcatctaat tggacttgtt cgtagaaaag
    24361 gtcttcgtat ttagaaacag aaagacgtgt tcgttgatcc agtaaagctt gtcgattagt
    24421 cattaacatt ttatcgtacc cagcaactaa ctgaccggaa taaaattcac ttacggcacc
    24481 ggaaccatag ctaaaaaaac caattttatc tccagattgt aatactttac tattttcaag
    24541 taaagataac aatcctagat aaagtgagcc agtataaata tttccaattt gtttgctata
    24601 actaatagaa gcttgaaagg cttctattag tttttccctg tgttcaggag gtactgtgtt
    24661 atccataatg ttatttagac cttttagggc taacttggga aatggaatat ggaaacaaac
    24721 tgcagcaaga tcagataact gaaggttttc tcttttctga taagcttgcc acgtggtttc
    24781 taagcaattg agatattgct tggtagagta aataccatca acataaggtg tgaaactata
    24841 gttaggcctc caaaagtcca taatatccct agtttgagcc acattatctt catttagagc
    24901 aagaatacga gggttagcag ttaccaaaag agcaatacta ccagagcctt gagtcgattc
    24961 cccaggagat cctacaccgt atctagcaat atcactagca ataacaagga cacgagaatc
    25021 tggcttagaa gccacatgca gtttagcata gtctagagca gcagttgcgc tatagcaggc
    25081 ttgttttact tcaaaggaac gtgcaaaagg ctggatacca actaagtgat gtacatagat
    25141 agctgatgcc tttgactgat cagtactcga ttcagttgcc aaaataacca tatcaatctt
    25201 agctcgatct tcgtcggtta aaatttgatc tgctgcagaa gcagctaaag taataatgtc
    25261 ttcagtgatt ggtgccacac taaaagactc aatgagtagc ccttgactaa attttgctgg
    25321 atccacttgg cgtgcaagcg ctaaatcttc caatttcaag acatattgac tggttgcaaa
    25381 accaatctta tcaattccaa ttgtcatatt tgtccttctt ttagttattt ttatagtctt
    25441 acccattcta tcacatttta ctgcaaaatt agactgataa agttatttgt tttatccttt
    25501 aatagttaaa atgttcatga ccacatgaag tttttcgaat gtttatttat tctggtattt
    25561 tttggtaaaa ttagttagaa tagtatgaag tatgcttaca gaaaggttat tagagatgac
    25621 aaaagctgac cagattttta aagctaatat tcaaaaaatt ataaacgaag gatcattgag
    25681 tgagcaagca cgtcctaaat ataaagatgg tcgaacagct cattctaagt atattactgg
    25741 ggcgtttgct gaatatgatt tagctaaagg agagtttccc atcacaactt tacgacccat
    25801 tccaattaaa tctgctataa aggaattatt ttggatatat caagatcagt ctaacagttt
    25861 agatgtgcta gaagctaaat ataatgttca ttattggaat gaatgggaag ttgaccagac
    25921 acgtactatt gggcaacgtt atggtgctgt agtcaaaaaa catgatatca tctcaaaaat
    25981 actaaagcaa ttagcagaaa atccttggaa tcgtcgtaat gtcatttctc tctgggacta
    26041 tgaagcattt gaggagacaa aagggttgtt gccatgtgcc tttcaaatca tgtttgatgt
    26101 tagacgtgta ggggaagatc tttatttaga tgctagtttg acgcaacgtt ctaatgacat
    26161 attagttgct catcacatca atgccatgca atacgttgcc ttgcagatga tgattgctaa
    26221 acattttgga tggaaaatag gtaagttctt ttattttgtt aacaatttac atatttatga
    26281 caaccaattt gatcaggctc aagaattgct aaaacgacag ccagttgcta gtcagcctaa
    26341 gcttgtttta aatgttccag ataggactaa tttctttgat attaaaccag atgattttga
    26401 attacaaaat tatgatccag tgaagcctca gttgcacttt gaccttgcta tttaaacttt
    26461 atttagattt tttgtgagca ttttgttcat aaatttggta aaataaatag agtttaaaat
    26521 gaaggaaata attaatgaca aaggaaatta ttgctatttg ggcagaggat gaagcagggc
    26581 ttattggtgt tgcgggtaag ttaccatggt atttaccaaa agagttagaa cattttaaaa
    26641 agacaacgct acatcaagca atcttaatgg gccgtgtgac ttttgaagga atgaattgca
    26701 aaagacttcc tcaacgtcaa acccttgtca tgacaagaaa tagagattat caagtagatg
    26761 aggtgttgac aatgactagt attgaaaaag tcttggagtg gtaccatgcg caggataaaa
    26821 cactttatat cattggtggg aataaggttt tagaagcgtt taatggttat ttcgatcgtg
    26881 tcataaaaac agttatccat catcgtttta aaggagatac ctaccgacca aatctagatt
    26941 ttagtcattt cacgcaagaa agccaaacgt tctatgctcg agacgctaaa aatccttatg
    27001 attttaccgt tactgcttta aaacacaaat agtctgagga gatgataagc gatgcaacgt
    27061 agtatttttg gagtatttac ggcttttttg tgcgtgattt gtgttctttg tgccattcca
    27121 gcttttaaaa agaatcgtta tggcttagca agtctgttct tattaaatgc gtttactaat
    27181 ctggttaata gtattcacgc cttctatggt acattgtttt gagatgcgac ttgcaaagac
    27241 agcactggtg aagatttagc tatcaagcaa gaatcaccaa aaaccaatac aacacattga
    27301 ctaatattaa aattcagtaa aagataagag aaagtaagag aattataaga aatggcagga
    27361 agtagaacta acgatattaa agtatactgt tcattttgtg gtaaaagcca ggatgacgtt
    27421 aaaaaaatta tcgcaggaaa taatgttttc atctgcaatg aatgcgtagc tttatcacaa
    27481 gaaattataa aagaagaatt ggctgaagaa gtccttgccg atttgacaga agttccaaaa
    27541 ccaaaagagc tccttgatgt tttaaatcaa tatgtggttg gtcaagatcg tgctaaacgt
    27601 gctttatcag ttgctgtgta caatcattat aagcgtgtct cgtttacaga aagtcgtgat
    27661 gacgatgatg tggatttaca aaagtccaac attttgatga ttggaccaac aggttcagga
    27721 aaaaccttct tagcacaaac tctggctaaa agcctcaatg taccatttgc tattgcagat
    27781 gcaacttctt tgactgaagc agggtatgtt ggagaagatg tggaaaatat tttactcaaa
    27841 ctgattcagg ctgctgacta taatgtcgaa cgagcagagc gtggtattat ttatgttgat
    27901 gaaatagata agattgctaa aaaaggtgag aacgtatcta tcacacgtga tgtatctggt
    27961 gaaggtgtac agcaagccct tcttaaaatt attgaaggta cggtagcaag tgttccccca
    28021 caaggtgggc ggaagcaccc taatcaagaa atgatccaaa ttgatacaaa aaatatcttg
    28081 tttattgttg gcggggcttt tgatggcatc gaggagatcg ttaaacaacg tttaggtgaa
    28141 aaagttattg gttttggtca aaacagccgt aaaattgatg acaatgcttc ttatatgcaa
    28201 gaaattattt cagaagatat tcaaaagttt gggcttattc cagaatttat tggccgctta
    28261 ccagttgtgg cagcccttga acaactaaac acatcagatt tgattcaaat tttgacagaa
    28321 ccaagaaatg ccctggtcaa gcaatatcag gctcttcttt cttacgatgg cgtcgaattg
    28381 gcatttgata aggaagcctt agaagccatt gccaataaag ccattgaacg taagacagga
    28441 gcacgtggtc ttcgttctat tatcgaagaa acgatgcttg acatcatgtt tgaaattcca
    28501 agccaagaag atgtcacaaa agtgcgtatc accaaggctg ctgtcgaagg caagtcaaaa
    28561 cccgttttag agacagctta aggagaaata atggctgaag aacaagtctt aaatacccat
    28621 aacgcatcaa ttttattgag cgctgccaat aaatctcatt acccccaaga tgatttgcca
    28681 gaaattgccc tcgctggacg ttcaaatgtt ggtaaatcaa gttttattaa taccatattg
    28741 gggcgcaaaa atttggcaag aacctcaagc aagccaggaa aaacccaact attaaatttt
    28801 ttcaatattg atgacaagct tagatttgtg gatgtccctg gttatggcta tgccaaggtt
    28861 tctaaaagtg aacgggccaa atggggaaag atgatcgaag aatacttaac cagcagagac
    28921 aatctgcgtg cagtcgtgag tttggtggat ttacgtcatg ccccttcaaa agaagatatt
    28981 cagatgtatg actttttgaa gtactatgac attcctgtta ttgttgtggc aaccaaagca
    29041 gataagattc ctcgtggcaa atggaacaaa catgagtctg tggtcaagaa agctttgaat
    29101 tttgacaaat ctgatacttt tatagtattt tcttcggtag aacgtattgg tatcgatgat
    29161 tcttgggatg ctattttaga gcaggtctag cgataggtgt tgatttatct atgctaaaac
    29221 attctcagta gagggtgttt ttcttatcga aaacataaaa aatcatagtt aggtttaccg
    29281 attttacttg acgccttaat gatgacatgc tagtatttta tattaaggag atgagtcatg
    29341 acacaagtag cccaagggcg ctctaaagga aagtcattgt tatgccatca atgcaatgcc
    29401 ctttttgtat ttattatttt tcttatcttg cttgctgtac tttttggtgt tcgatatcgt
    29461 aatagctcta ttgaaggtat ctggcgaaca acaagcattg atcagaagtt aggcgatgat
    29521 tttgctaaac gtcttactgg tttgcatcag agccctctta ttgatgatag tttattaacg
    29581 tcatctcaga tgatactaac agttaaaaat aacaacgttg acttgagttt tagtgttcaa
    29641 gttgaacgag acatttttgt caaacgttta gctgcttatc accaaaatga attattaaag
    29701 acattaaagg aaaatcattt agttgttggt gacttgagta gtaaagaacg ccaaattatt
    29761 gagaatagta tgccagctag ccatgaatta gaaatgattt tagatcaagc ttttgagaaa
    29821 ttagcttctc agatcggagg caaatataat caaaaaacag gacatttatc tgctgttgtt
    29881 ctcaaaggaa aagttaatcg tattttgcac accattgata tcaaagaaga agtagcagcg
    29941 ggacatactt ctttttcaaa aggattactc acacctaatg gttattttga ttacaccaga
    30001 tttggaaaga aacttgagtt attaggcgat gaaaaaatta tttttaaaaa agcgctaaaa
    30061 aaaagtccgt caagtgtata acgtagtcac aagacggatt ttttcatgtt ttgaaaatta
    30121 ttcaattgaa gaagtttatt actgatcgtt ttgcctaatc actagttgtc cttcttttag
    30181 gattgcctga agttttttga cttctggatg gtcaagataa taatcagtta tacggtcacg
    30241 aatttcctgt tcgataatac gtcgtaatgg acgagctccc atagcgtgat tgtaccctaa
    30301 atctatcaaa tgagctttag cgtcatcagt aatcgttaaa ctaatacctt tttttgcggt
    30361 ggtttgattt acttcagcta gcattaaatc aacaatttct tctaaacttt ctttttgcag
    30421 atgattaaat ttaatgatac tattaaaacg gttcaaaaac tctggtctga aataaggtgc
    30481 aatgcgatcc ataatgttag actcagaagt ttccgtatct tgttggccaa aaccggcatt
    30541 tgatgtagca ataataacgg tatttttaaa gttaatagta tttccttgtc catctgtcaa
    30601 tcgtccatca tctaatactt gtagaagaag tgtaataatt tgaggatcag ctttttcaat
    30661 ttcatctagt aagacaatag cataagggtt acgacgaaca cgctcagtta gggtattatt
    30721 attatcatcg tagccaacat aaccagccgt tgtcccaatc aattttgaca cagcagtgcg
    30781 atcgttatat tcggacatat caagtcgaat aatagcatct ttggaaccaa ataaatcaag
    30841 tgctaattgt ttagctaact ctgttttacc aacaccagtt ggacccacaa aaaggaaaga
    30901 acctattgga cgtttaccat catcaaaacc tgcccgattt cgtcgaatag cacgtgctac
    30961 tgctgcgaca gcctcatctt gtccgatgac atggcttttt aagcggctgc taattccttt
    31021 gagcctttct aaatcattag tccccatgtt agagacagga ataccagtta agcgctctac
    31081 agactctgcg atatcattga ctgtagcagt gacattttgg ctttggttat gttgctcaat
    31141 ttgcttttgt aatgtttcaa tccgtgtttt tgctgctaaa gctttttcaa agtcttcttt
    31201 ggcgacagct ttttcttgac tctctttttg tttagctatt tcagtttcga gtgtttttaa
    31261 gtcagtgacc gggtgttgcg cagctaaatg agcagctgtc atatccagta agtcaattgc
    31321 tttatctggc aggctacgct gtgggatgta ttgaatagaa taatcaacag cagcttttag
    31381 aacattatca ggaagggtaa tatggtggtg ttgttcataa agattacgaa tacccattaa
    31441 aatgtgaaaa gtatcttcag ctgatggtgc attcacttta acttcattaa agcgacgagc
    31501 aagagcagca ttttttaaaa tagtattgcg gtattcgtct tgagtagtag caccaatcag
    31561 tgttaattct cctcgtgaca aggctggttt aagaatatct gcaagtccct ttgagcctga
    31621 atcactgctt gtggcaccag caccaactat ttgatgaatt tcatcaaaaa ataagatgat
    31681 attcccagct tcttttactt cttgaatcaa gttttgaatg gtctcttcaa aggaaccacg
    31741 atactgtgta ccagcttcaa gactagaaat atcaattgat acgatttcct tgtttttaat
    31801 agcagctggg acatctccat taacaatggc ttgagctaaa ccttcaatga ctgcagtttt
    31861 accgacacca gcatctccga caaggacagg attattttta gttcgtcgtg ccaagatttc
    31921 agcggtatct tgaatttctt tgttacgacc aatgacgggg tcaagatgcc cttgacgagc
    31981 ttcttgtgtt aagttagttc cgagttgagt caatacacta tcagctttag gtgttaacat
    32041 ttgagaattt gttgctttgg ttgtcgctac agggagttgt cctgtttgac gatagtgttg
    32101 gaattcttcg ggagttattt cgcgaccgtt aacgagatag cggggatttt cgctacgata
    32161 accacccatg tttgccatta attgattgaa aatatcatcc atatttacaa aaggatcttt
    32221 accagaaaaa tgtgtcatat cagttacctc gcaataaaaa atagactata agatgtttgt
    32281 aagcagtcgc agaatcgttg ttaggatttc acatgatagg aaatcctttg ctaataaaat
    32341 gattcagaca ttatttttac tcatcttata gtattattat aatcaaaagg tcagtaaagg
    32401 tcaaacaaaa aacacttgat tttcaaaaag ctaaataaac acgaaaagta agtgcttata
    32461 tgatgacttt agaataaatc ataagtttta aaaagatcat cctattctat agcacttagg
    32521 ctgtcaatga gagaaaaaca aatgttttca ttaacaagtt ggcgctttca tggtataata
    32581 aagtgctaag acgcaattct attataaggg ggaatcatgg aagcactcaa aaaaattgcc
    32641 ggtgttaccg ctgcgcaata tgtgactgat ggcatgacca ttgggcttgg aactgggtca
    32701 acggcttact attttgttga ggaaattggc cgtcgcgtaa agcaagaagg actgcaagtg
    32761 gttggtgtga ctacgtcaag tgtgactagc aagcaagcag aagtcttggg cattccttta
    32821 aaatcgatag atgatattga tagcattgac ctcaccgtag atggtgctga tgaagtggat
    32881 aagaatttca atggaatcaa gggtggcggc gcagccttac taatggaaaa aattgttgca
    32941 acaccaacaa aagaatacat ctgggttgtt gatgcttcta aaatggtaga gcatctgggt
    33001 gcctttaagt taccagtcga agtcgttcaa tatggtgctg atcgtttgtt ccgtgtcttt
    33061 gaaaaagctg gttacaaacc gtcttttcgt atgaaaggtg atagtcgttt ggtgacagac
    33121 atgcaaaact atattattga tcttgatttg ggttgtatta aagatcctgt tgcttttggt
    33181 cacctgctag atggaacagt tggtgttgtg gaacacggtc tctttaatgg tatggttgat
    33241 aaggtgattg ttgctagtaa agacggcgtt actgttttag aagcgcctac agcaggctag
    33301 tcttagcata taacagcgtt aatatatttt ataggtattg gggagtcaac cgtaacctcc
    33361 cctagattgg agacttatgt caaaatttaa tcgtattcac ttggttgttt tagactctgt
    33421 cggtattggt gcagcaccag atgctgacaa attctttaat gctggtgtag ctgatacaga
    33481 ttctgacacc ctcggtcata tttcagaagc agcaggctta tcggttccaa atatggcaaa
    33541 aattggactt ggaaacattt ctcgtccaat accactaaaa actgttccaa cagaagacaa
    33601 tcctactggt tacgtgacca aattggaaga agtatctctt ggaaaagata ccatgacagg
    33661 ccattgggaa attatgggct tgaacattac ggaacctttt gacactttct ggaatggttt
    33721 cccagaagag attttaacta agattgaaga attctcaggc cgcaaaatca ttcgcgaggc
    33781 caacaaacct tattcaggaa ctgcggttat tgatgatttt ggtccgcgtc aaatggaaac
    33841 aggtgagttg attgtttaca cctcagcaga cccagtgctt caaattgcag cccatgaaga
    33901 cattattcct gtggaagagc tttacaagat ttgtgaatat gctcgctcca tcacgcttga
    33961 acgccctgcc cttttaggcc gtattattgc gcgtccttat gtaggcgacc caggaaactt
    34021 tacacgtacg gctaaccgtc atgactatgc agtgtctcct ttccaagata ccgttttgaa
    34081 caaactggct gacgcaggtg tcccaactta tgccgttggt aagattaatg acatctttaa
    34141 tggttcaggt attacaaacg acatgggaca taataagtcg aacagccatg gtattgacac
    34201 gcttattaag actcttcaat tacctgagtt tactaaggga ttctccttta ctaacctcgt
    34261 tgattttgat gccaactttg gtcatcgtcg tgacccagag ggttatcgcg actgcttgca
    34321 tgaatttgac aatcgcctac ctgaaatcat cgcaaatatg aaagaagacg atttgcttct
    34381 catcactgct gaccatggta atgacccaac ctatgcaggc accgaccaca ctcgtgaata
    34441 cattccattg cttgcctact ctgtatcctt tactggaaat ggtcttattc cacaagggca
    34501 ttttgcggat atttcagcaa ctgttgcaga aaattttgga gttgatacag ccatgattgg
    34561 ggagtcattc cttagtcact taaaataaga aagttagtaa ttgataatgg aagaaatcac
    34621 gatttatcat aatccaaact gtggcacttc acgtaatgtt cttgccatga ttcgccatgc
    34681 aggtattgag cctactatta ttgagtattt gcagacgcca cctaatcggg agactttaat
    34741 tgagctctta caatcgatgg gaatctctgc aagagaactc ttgcgaacca atgttcctga
    34801 atttgaggct tatggattag caaatcaagc agtagctgag aaagacatta ttaatgccat
    34861 gttggcggat ccaattttga tcaatcgtcc tattgttgtg actcgcaaag gagtaaaact
    34921 ttgccgtcct tctgagacct tactggatat tcttcctgtt cccctgccta gtccttatat
    34981 taaagaggat ggcgagagtg tgaaccctat tgaggtaaaa ggagaaaaag atgtcattga
    35041 tgactaaaat taacgaaaca aaagactttt tagttactaa aggaattgaa actccagaat
    35101 ttggattaat tctgggttca ggccttggtg aacttgctga agaagtagaa aatgctattg
    35161 ttattgatta tgcagatatt ccaaactggg gcaagtcaac ggttgttggc catgctggaa
    35221 agttagttta cggagattta gctggccgta aagtgctcgc cttacaagga cgtttccatt
    35281 tttacgaagg aaatccgctt gaagtggtga ctttccctgt tcgtgtcatg aaagctctgg
    35341 gatgtgaagg cgttcttgtc acaaatgcag ctggtggtat cggctacggc ccaggtacct
    35401 tgatggcaat cacagaccat atcaatatga ccggaaataa cccactaatc ggtgaaaact
    35461 tggacgagtt tggtccacgc tttcctgata tgtctgatgc ctatactaag gtttatcgca
    35521 ataaggcaca tgaagtggct gaaaaaatga acatcaaact agaagatggt gtttatatgg
    35581 gcttgactgg tccaacttat gaaacaccag cagaaatccg tgctttcaaa gtattaggag
    35641 cagatgctgt tggcatgtca actgtaccgg aagttattgt ggctgctcat tctggactta
    35701 aagtgcttgg tatttcagct attacaaact ttgcagctgg tttccaatca gaattgaacc
    35761 atgaagaagt tgtggaagtg acccaacata tcaaagaaga tttcaaaggt cttgttaaag
    35821 ctattttagc ggagttgtag gacgaacaaa atcaactgga gcattattac aggaatgtta
    35881 ttttatgtcg tcagtttggc acatctgttc gcaataaaaa aatcaaaaaa taatcacgga
    35941 gtgtgagttc catgaatgtt gaactcagat tctagctttt ctaactaaca taaccaacga
    36001 agggaaagag acgtattcgg tttaaattga gtatggactc gaacatttct tcgtattaat
    36061 ttttaaataa taaaggaaag agagttagtc ctttcttatt tgaactcgat ttttagctct
    36121 cttctattca atatcaatta tgaaaggaat ggggttgtat tcaattgaat acgggcggaa
    36181 agctcggaaa ctagataaac taacttttga gctcacacat ggcgttagtt ccctaaattt
    36241 cagtcgcttt ctgtccgccc tctgaccttc tacaaaataa aaggaaaggt agggctaact
    36301 gtattcattg aattgaatac gggcggagaa ctgtttttct tccttataaa aaataaaaaa
    36361 ataagaaagg tgagggctga gttcattaat ttgaattcgg gctaaggact tggtcaaaaa
    36421 gataagttgt ctagaaaatc aggattttct gccaacttcc tattttgcca tcgttctttt
    36481 aacgccctca gtatcataat ttatgtctat ccatatttct gccaaaaaag gcgatattgc
    36541 tgataaaatt cttctacctg gagatccttt gcgcgcgaaa tttatcgctg aaaatttcct
    36601 agaagatgca gtgtgtttta acgaagtgcg taacatgttt ggctacacag gaacttacaa
    36661 agggcaccgc gtttctgtca tgggaactgg tatggggatg ccttcgatct ctatctatgc
    36721 tcgtgaatta atcgttgatt acggtgtcaa aacattgatc cgtgttggta ctgcgggtgc
    36781 gattgaccca gaagttcatg tgcgtgaatt ggtgcttgcc caagcagcag caaccaactc
    36841 aaatattatc cgtaatgact tcccagaatt tgatttccca caaattgctg attttggttt
    36901 acttgacaag gcttaccata tcgccagaga aatgggagta acaactcacg ttgggaatgt
    36961 gctttcttct gatgtctttt acactaacat gcctgagcgt aatatggctc ttggtaaatt
    37021 gggtgttaaa gccatcgaaa tggaagcagc agctctttac tatttagctg ctcagcacca
    37081 tgtcaaagcc cttggaatca tgacgatctc agataacttg aatgatccaa ccgaagatac
    37141 tacagctgaa gagcgccaaa caactttcac tgatatgatg aaggtcggct tggaaacctt
    37201 aattgccaat gactaataat caaacactag acatcctttt ggatgtctat gcttataatc
    37261 acgcctttag aattgctaaa gccttgccaa atatccctaa aactgccctc tatttactag
    37321 agatgttaaa agagcgcaga gaattgaacc ttgcctttct agcggaacat gcagcagaga
    37381 atcggaccat tgaagaccag tatcactgtt cattatggct taaccaatcg cttgaagatg
    37441 agcagattgc caattacatt ttggatttag aagttaaagt aaaaaacggt gctattattg
    37501 atttcgtcag gtcagtgtcg cctattcttt accgactttt tctcagacta atcacgtcag
    37561 aaattccaaa cttcaaggct tatatttttg atacaaagaa tgaccaatat gatacctggc
    37621 attttcaggc catgttggaa tctgatcacg aggttttcaa ggcttacctg tctcaaaagc
    37681 agtctcgcaa tgtgacgacc aaaagcttag cagacatgtt gacgttgacc tccttacctc
    37741 aggaaatcaa ggacttggtt tttttgttac gacattttga aaaggctgtc cgtaatcctc
    37801 tggctcattt gattaagcct tttgatgaag aggaactgca tcgcaccact catttttctt
    37861 ctcaggcttt tttggaaaac attatcacct tggcgacttt ttctggtgta atctaccgac
    37921 gtgagccttt ttactttgat gacatgaatg ccattattaa aaaggagttg agcctttgga
    37981 gacaatctat tgtctgatat ttatcaaaaa acacgataac ttgaccgata caggtcttac
    38041 taccgtgttt tttagtatga cgattgaaaa agacattaat caaaggttac ttcttcgaga
    38101 aggtattcga taaaacgttc ccccattttg gacaagttgg ctttttcatg cttgataaaa
    38161 acaatgtcaa tttcgtcagg gacatctagc gggatagcca caatctggtc accatttaga
    38221 ttgctattta gaataccact ggcaacggtg tagccatcta aaccaatcat taagttaaag
    38281 agggtggcac ggtcactgac cacaattgat ttgttgtggg gcatctggga catcatctct
    38341 tctgaaaaat aaaaggagtt gtgaatccct tggtcatagc tcaggtaagg aaaatctctc
    38401 aagtcgtcca tgcttaatag gcttttagtt gctagaggat ttgatttgct gacaaaaata
    38461 tgaggctgtg ccttaaataa tggagaggcg gtcaaatgat tgtcatcaaa taatttggtc
    38521 aagacatctc ggttatagtc gttgataaag agaacaccaa tttcagatcg aaagtttttg
    38581 acatcatcaa tgatttccca agttcttgtc tcgcgcaaaa agagttcata ccgagtcatg
    38641 tcggtccgct tgaggagtga gacaaatgca ttgactacga aggcataatg ttgagatgaa
    38701 acgctaaaga gctctcggcc agtattgtgg tttttatagc ggtcttctaa cagtgatgtt
    38761 tgctctataa tttggcgagc ataagataaa aattccaccc catcttttgt caaggtgatc
    38821 cctttaggat ttcggttgaa aatggtaatg cccatctcca tttccaaatc cttgaccgca
    38881 ttggatagac ttggttgtgt gataaataat tgcttagcag cttcattcat agagccgcac
    38941 tcaacaattt tgataatata atgcagttgt tgaattctca taagtacagt ctagctcaaa
    39001 aaaaataaag acgcaagcac aaacgtcatc atgggtttag aactttgaaa aagcgctgga
    39061 gtcttttctc aatatggcct aggataaata tgattcaatt ttgagagttg aatctatcaa
    39121 tttcattgcc cttttatttt tcttgtgtta tattaatagt attaacaaat aggtattttt
    39181 ctaatcaaag ggtggtggtc gtgtgaatgt tactgaacaa aatagtcatc aaatcttaat
    39241 ccaaaagtta ttggtcagta tccactattt gactcttttt cgagatgaac tgaagcttgt
    39301 agaacgaact ccttctatac ttggagggga atttccagct catttagtac agtctgagtt
    39361 gggagatatt gttgcggcca ttgatacctt ggatatgcag caacgcttga ttgagtctac
    39421 cttttggtat gaagaatcag cttttaagtt gatgaacaaa actttggata ttgtcgataa
    39481 ttggattaaa ggagtggatc atctgataga tttatgccag tccaaagaag tctttcaaat
    39541 tattattgga gataaacgca ttcgagtttt tggggtctta agtgatgttt tttcatcttt
    39601 aaaagtgagt gctttgtcac ttaaggaagc tcctattccg gatgtgctct atgaacatat
    39661 ccagagggtt aatcttgaag aagaagcttt tataaaatat taccaaagcc ctaaggtacc
    39721 cacaggtgag tttgaataaa tgattgggta aaaatgataa aatgagttga cgtaagtata
    39781 caaaaaaaga tatagtagga aagatgtgtt caaataacaa aaagttttga catcttgttt
    39841 taaaaaagct ataatagttt aaatttagac acctttaagt gagtccagag aggcaaacaa
    39901 ggtatacaag ataaaaaaag ggaattccct tttagtttgc tgtagcctcg cttctttggt
    39961 agcgaggctt tttggtgctt aatgagatat tgacacatta tagaaaggat aagttatgaa
    40021 agaagaacgc ccaattattg ctttagactt ttcatcattt gaggagacta aagcattttt
    40081 agacttattt ccagcagaag aaaaactata cgtgaaaatt ggtatggaat tatattatgt
    40141 gcaaggacca gatattgttc ggtatatcaa atcgttaggg cataatgtat ttttggattt
    40201 aaaattacat gatattccaa atactgttcg tgctgctatg gcagttctta aagaattaga
    40261 tattgatatg gcaactgttc atgcagctgg tggtgtagag atgctaaaag cagctcgaga
    40321 aggactaggt caaggcccta ccttaattgc ggtaacgcag ctaacttcaa ccagtgaaga
    40381 ccaaatgcgt ggtgatcaaa atattcaaac gagtctttta gagtctgttt tgcattacag
    40441 caagggggca gctaaagctc agctagatgg ggcggtttgt tcggcacaag aagtagaagc
    40501 tatcaaggcg gtgacgccta cgggatttac ttgcttaact cctggcattc gtcctaaagg
    40561 cagtaatatt ggcgatcaaa aacgagtgat gactccaaac caagcaagac gcattggaag
    40621 tgattatatt gtggtagggc gaccaattac ccaggcaaaa gacccagtgg ctgcttacca
    40681 agccataaaa gctgagtggg caggctaaca gataagatta ggaaaccaac acttgtctgt
    40741 taaagaagaa aaaggagaat aagaaatgac actagcaagc caaattgcaa ctcaattact
    40801 tgatattaaa gctgtttatt taaagcctga agaccctttt acgtgggcat ctggcattaa
    40861 atcacctatt tacactgata atcgtgtcac cctttcttat cctaagactc gtgatttaat
    40921 tgagaatggg tttgtggaaa ctatcaaggc tcatttccca gaagttgagg tcatcgctgg
    40981 tacagctaca gcaggtattc ctcacggtgc cattatagca gataaaatga ctcttccttt
    41041 tgcttatatt cgcagtaagc caaaagatca tggagcaggc aaccagattg aggggcgtgt
    41101 gcttaaaggc caaaaaatgg ttatcattga agatttgatt tcaacaggtg gttcggtact
    41161 agatgcagcc gcagcagcca gtcgtgaggg agctgacgtt ctgggagttg ttgcgatttt
    41221 cacttatgag ttaccaaaag ctagtcagaa ttttaaagaa gctggtatca agttgattac
    41281 gctttctaat tatactgagc taattgcagt tgcaaagttg caaggctata ttactaatga
    41341 tggtttacat ttacttaaaa aatttaaaga agaccaggta aactggcaac aataaggaac
    41401 tatcagccag gtttattttt aatgaaaaaa tctctttagc cccaattcaa aatgttatgt
    41461 tttgattgtt ttgtctacat tccttacaca tcacattcta atttctaacc ttttaatggt
    41521 ggttttcttt tatttgtgtt ttaataaaaa agaatgtttt aggattcata tcttagaaag
    41581 gaagagtagc tatgacttat caagatgcga cggctatggc tattgctgtt cagactggtc
    41641 agaccacacc actagaatta gtaacccagg ctatttataa ggctaaaaag ttgaacccta
    41701 ccttaaatgc tattacctca gaacgctttg aagcagccct agaagaagcc aaacaaaggg
    41761 atttttcagg tctgcctttt gctggtgtgc ctcttttttt aaaagatttg ggacaagaat
    41821 taaaaggtca ctcatcaacc tcaggttcca gattgtttaa agagtatcaa gcgactaaaa
    41881 cggatttatt tgtgaaaaga ttagaagctt taggctttat tattttaggg cgctccaaca
    41941 cgcctgaatt tggctttaaa aatattagcg atagcagttt gcacggacca gtgaatttac
    42001 caagggataa tacacgaaat gctggtggct catctggggg agctgctgct ctagtgtcat
    42061 caggaattag tgcgctagca actgctagtg atggtggtgg ttctattcga attccagcct
    42121 cgtttaatgg cttaattggg ctcaaaccta gccgtgggcg catgcctgtc ggacctggtt
    42181 cttatcgaag ctggcaagga gcctcagttc attttgcctt gaccaaatcc gttagagata
    42241 ctagaaatct actctactat ttacagatgg aacaaatgga aagccccttc cccctagcca
    42301 ccttaacaaa agatagtatt tatcaatcgc tacaacgtcc cttgacaatt gctttttatc
    42361 aacggttaag tgacggtagc ccagtatctt tagatactgc aaaagcttta agacaagcag
    42421 taacttggct aagagaacaa gggcatcagc tagttgaatt ggaagagttt cctgtaaata
    42481 tgacagaagt gattcgtcat tattatatta tgaatagtgt ggaaacggct gctatgtttg
    42541 ctgatattga agacactttt ggacgtccga tgaccaaaga cgatatggaa accatgacct
    42601 gggctattta ccaatcaggt aaagacatcc cagcttggcg ttactcacag gtccttcaaa
    42661 aatgggatac gtacagtgca accatggcta gttttcatga gacttatgac ctgttgttga
    42721 cgttcacaac caacacacca gctcctaagc acggagaact tgtcccagat tcgaaactca
    42781 tggctaactt ggctcaagct gaaattttca gcagtgaaga gcaattcaat ttggtcgaaa
    42841 ccatgtttgg taagagtctg gctattaatc cttacacagc tctgcctaat ctaactggcc
    42901 agccagctat tagtttacct acttatgaaa ctaaggaagg tctctcaatg ggcattcaac
    42961 taattgcagc caaaggtaga gaggacctat tattaggaat tgcagaacag tttgaggcag
    43021 caggattatt gaagattcct caataataat cttataaaac agtttaacta ttatagatta
    43081 actttttaaa gagattgagt gctcactgat aacacaactt aatcaaaatg ttatactatt
    43141 cttatcttaa taaaggagtt actatgaaga aatcagttac attactgtct atcggacttg
    43201 ccagcctttt attggcagca tgtgcgccac atcaatctca aaaatcaagt tgggacacta
    43261 tcaaagaaaa aggggtgtta aaagtagcta ccccaggaac ctatcagcca acttcttttt
    43321 acaacgataa taatgagtta gtaggttacg aagtagatat ggtcaaagaa atcggtaaac
    43381 gacttaacat taaagtcaag tttgttgaaa caggatttga ccaagccttt acctcagttg
    43441 atagtggtcg agtggatatt tctttgaaca actttgacat taccccaaaa cgtcagaaaa
    43501 aatacaatat ctctacgcct tataaatacg gggtaggagg catgattgtc cgtgctgatg
    43561 gcagctcaaa catggctaaa aaagatctta gcgactggaa aggaaaaaaa gcagccggcg
    43621 cttctggaac agaatacatg aaagtagcgc aaaaacaggg agctgaactg gtgacctacg
    43681 ataatgttac aggagatgtt tatctaaacg atgtggctaa cggtcgaaca gatttcatcc
    43741 caaatgatta cccagctcaa aaattatttg tggattacat gttatctcaa aatccaaatc
    43801 taaatgtcaa aatgagcgat gttcagtaca acccaaccga acaaggaatt gttatgaaca
    43861 aaaaagacga tagcctcaag aaaaaaatag atgctgttat taaagacatg ataaaagatg
    43921 gtagcttgaa gaaaatctct gaaacctacc atgctggtca agatctgaca aaaccttttg
    43981 gcaaagacaa aaaaattccc gtcattgata cgaaagacgt taactaatac ttgatgttaa
    44041 aggagtccta accacatgat taatatccca ttaatgaaag atagtttagg atttgtgtta
    44101 tcgggattac cttataccct tggtatttcg ttgctcagtt tttttacggg tctgttttta
    44161 ggtttaggcc tagcccttct gggaaggtca cgtcagccgt tgattcatta tcttgttaga
    44221 gcgtacatct ctattatgcg aggtgtgccg atgatcgtgg tgctctttgt tctttatttc
    44281 gggttgcctt attatggttt agaattgcca gctttacttt gcgcttatct tggtttttct
    44341 atggttagcg ctgcctatat ttctgaagtt tttcgctctt ctatagaagc tattgacaag
    44401 ggacaatggg aagcagctaa ggctttaggg ttgccatatg ctcttatggt taagaaaatt
    44461 attcttcctc aagcctttcg aattgcagtt cctcctttag gaaatgtcat tattgatatg
    44521 gttaaaagtt cgtcgctagc tgccatgatt accgtaccag atatttttca aaatgccaaa
    44581 attattggcg gtagagagtg ggattacatg tccatgtata ttttagtagc ctttatctat
    44641 tggcttattg cttttttgtt agaacgttac caagaattct tagaaaataa gctagcactt
    44701 gtttaatatc ctgtaaaaaa cgaatattaa ccctggaaat atcatatttt cagggtcttt
    44761 ctatttaaaa tgtggtaaac tagatagaaa aggacatcgt atttaactta gaaactgacg
    44821 tgattagaaa ggaatcttat ggctcattca atttggcatg agaaaatcaa atcatttttg
    44881 ccggagcatt actacggtcg catcaatcac tttttagatg aagcctatgc ttccggtctt
    44941 gtctatcctc cacgagaaaa tgtctttaaa gccttacaag tcactccttt ggaagaaacc
    45001 aaagtgttga ttttaggaca agacccttat catggcccca aacaggccca gggcttatca
    45061 ttttcagttc cagaagagat ttctgctccg ccatccctta ttaatatttt aaaagaatta
    45121 gcagatgaca ttggtcctcg tgaccatcat gatttaagca cttgggctag tcaaggggtt
    45181 ctgcttttga atgcttgctt aacagtgcca gcaggccagg ctaatgggca tgcaggctta
    45241 atatgggagc catttacaga tgctgttatt aaagtgctga atgagaaaga cagccctgta
    45301 gttttcattt tgtggggagc ttatgcaagg aagaaaaaag ccttcattac taatccaaag
    45361 caccacatca tcgagagccc tcatccaagc cctttgtcat cttatcgtgg cttttttggc
    45421 agcaaaccct tttcaagaac caatgctatt ttagaaaaag agggcatgac tggcgtagat
    45481 tggctaaaat aagccagcca tttcaactaa atagcttaat ctagacattt tgataccttt
    45541 aataagtgaa atgagtgcag tagatttttc ctattaaaga acgtaaggtc ttatggttaa
    45601 aacagataaa taaaggagaa aacatgatac tcatcaaaaa tggacgcgtt atggacccga
    45661 aatcgcagag agatcaagtg gcagatgtct tgattgatgg taaacagatt gtaaagatag
    45721 cttcagctat tgaatgccaa gaagctcaag tgattgatgc tagtggtctt attgttgccc
    45781 cgggtttggt cgatattcat gtgcatttta gagaacccgg tcaaacgcac aaagaagata
    45841 ttcacacggg agccttggca gcagcagcag gtggtgtgac tacggttgtc atgatggcta
    45901 ataccaatcc tgtcatttca gatgtcgaaa ctttacagga agtgctagct agcgcagcta
    45961 aagaaaagat tcatatttac accaatgcca gtgtcaccca agcctttaat ggaaaagacg
    46021 tgactgattt taaagctttg ttggaagcag gagcagtaag cttttcagat gatggtattc
    46081 ccttagaaag ttctaaagtt ttaaaagaag cctttgattt ggctaatgcc aaccaaactt
    46141 tcatttcttt gcatgaggaa gatcctcagt taaatggggt tcttggtttt aatgaaggta
    46201 ttgctgagga gcattttcat ttttgtgggg caactggtgt agcagaatat agtatgattg
    46261 caagagatgt catgattgct tatgacaggc aagctcatgt tcatatccaa catttatcta
    46321 aagcagaatc ggttcaagta gtggcttttg ctcagcagtt gggtgctaag gtaactgctg
    46381 aagtgtcccc acaacatttt tcaacaactg aagatctctt attgatcgca ggtaccagcg
    46441 ccaagatgaa tcctcccctt cgtacacaaa gagatcgctt agctgtcata gaaggcttga
    46501 aatcgggtgt tatcacagtc attgccactg atcatgctcc tcatcacaag gatgaaaaag
    46561 ctgtggatga tatgactaaa gccccatctg gtatgacagg acttgaaact tctttgtcat
    46621 taggtttgac gcatttggtt gaaccaggtc atcttacact tatgtcacta ttagaaaaaa
    46681 tgacgcttaa tccagctttg ctttatggtt ttgatgcggg ttatttggca gaaaatggtc
    46741 cagcagattt ggttattttt gcagacaagc aagaacgtct gatcactgag aattttgctt
    46801 ctaaagctag taattcccca tttattggta acaaactcaa aggtgtcgtg aaatacacta
    46861 ttgcagacgg agaggttgtt taccctaatt aacaaatgag ttaaaacaaa aaagcttgac
    46921 tttcagagaa agtcaggctt ttagtaaatt tattttttag gcacttgttt gcttaaattt
    46981 agcccccaag gtattagatt ttcagtatga tgtttgatac gactaatgtt atctttgtgt
    47041 cttataataa taatgaacgc aagtaatatc acaataaaag ttaaaaagta gtcataattt
    47101 ggtaaaagaa aatgaatggc aggaaatgtt aaaacagata acacaccaac gatagctgaa
    47161 accacactag ctaaagatat catactaaat aaatagagaa ctaaaacaaa gatagatgct
    47221 aaaaaaaaga gatataacgg agcaaagcct agcaatacac cagcacttgt tgctacggcc
    47281 ttaccacctt taaagttggc aaaaatagga aaagtatgcc ctaaaactgc gaaaaagccg
    47341 atagcaatgg atgaaattga agtcatacca aaaataattg gtaacaatat tgaaagtgtc
    47401 cctttaaaca tatcaatagc taaggtagct gttcctgcct tgacacctaa aatccgaaaa
    47461 gtatttgtgg ttccagtatt tcctgatcca tgctctcgta agttgatgtg gtaaaagtac
    47521 tgtccaatcc atagtccagt tggaatagaa ccaagtaaat aggcaatggt aataaaaagt
    47581 agtaatttca taatccttat tataacatat tcatagattg gagaactaga tctggaaaag
    47641 aattcggaaa aaattagcaa attattttgc aaaattggta aaaaacttgt aagataaaaa
    47701 agatgaaact gtctggaggt cggtgttgac taagaaagaa attacaatta ataattataa
    47761 tgacgatgct atccaagtcc tagaagggtt agatgctgtt cgcaagcgtc cagggatgta
    47821 tatcggttca acagatgcta cgggattgca ccacctgatt tgggaaattg ttgataatgc
    47881 tgtcgatgag gccttgtctg gttttggaga tgatattaag gttgttatca ataaagatgg
    47941 ctcggtcagt gtggcagata gcggacgtgg aatgccaaca ggccagcatg ccatggggat
    48001 tcccaccgtt caagttattt ttacgattct tcatgcaggt ggtaaatttg gtcagggtgg
    48061 ctacaaaacg tcaggtggtt tgcacggtgt tggctcctct gttgtcaatg ctttgtctgc
    48121 ctggttagaa gtcgaaatca caagagacgg gtcagtgtat cgtcagcgct ttgaaaatgg
    48181 tgggaaacct gttacaaccc ttaaaaaagt tggcacagct cctaagtcta aatcaggaac
    48241 ggttgtaacc tttatgcctg atgataagat tttttcaact attgacttta agttcaatac
    48301 catttcagaa cgattgaaag aatctgcttt tcttttgaaa aatgtcaaga tgagcttgac
    48361 agatcttcgt ggagatgacc cgattattga agagtttcat tatgaaaatg gggttcaaga
    48421 tttcgtcgaa tacctcaatg aagataagga aaccttgaca cctgttattt acatggaagg
    48481 tcaagaccaa gactttcaag tcgaggttgc tttgcagtat aacgatggtt tctccgacaa
    48541 tatcttatcc tttgtaaaca atgtgcgcac caaagatggt ggaagccatg aaacgggact
    48601 aaagtcagct attaccaaag cgatgaatga ctatgctcgt aaaaccaatc tcttaaaaga
    48661 aaaggataaa aatctagagg gctcagatta tcgagaagga ctctcagcag tattatctat
    48721 cttagttcct gagcagcact tgcaatttga aggacagacc aaagacaaat tgggaagtcc
    48781 tttagctaga cctattgtag agagcattgt ttctgaaaaa ttaaccttct ttttactcga
    48841 aaatggagaa gtagcttctc atctagttcg caaagccatt aaagctagag atgctcgcga
    48901 agctgctcga aaagcgcgtg atgactcacg taatggtaag aaaaacaaaa aagacaaagg
    48961 cttgttgtcg ggaaaactaa ccccagctca gtccaaaaat gccaagaaaa atgaattgta
    49021 tctggtcgaa ggagattctg cgggaggttc agccaaacaa ggacgagacc gcaaatttca
    49081 ggctatttta ccattacgtg gcaaagtttt aaataccgaa aaagctaaga tggctgacat
    49141 cttgaaaaat gaagaaatta acactatggt ttataccatt ggagctggag tgggagctga
    49201 ctttaacctc gaggatatca actatgataa gattattatc atgaccgatg ctgataccga
    49261 tggggctcat attcagactc ttttgctgac tttcttttac cgttatatgc gaccgttggt
    49321 ggaagcaggt cacgtttata ttgcgcttcc cccgctttac aaaatgtcaa aaggtaaagg
    49381 caaaactgaa aaaattgctt atgcttggac tgatggtgaa ttggaagatc tgcgcagaga
    49441 atttggcaag ggggctattc ttcaacgcta taaaggactg ggtgaaatga atgctaacca
    49501 attatgggaa accactatgg accctgaaac cagaaccctt attcgtgtta ctattgacga
    49561 cttggcaaga gcagagcgac gtgtttctgt gttgatgggt gacaaagcag ccccacgccg
    49621 tcagtggatc gaggataacg tcaagtttac cttagaagaa aatacggtgt tttagtcata
    49681 caagtttctc acagataatt acaagtgcta aagacgattg ttttttaggt aattaataaa
    49741 taatgaaaaa gaaagctatt tgaatatgtc aaacattcaa aacatgtccc ttgaggatat
    49801 tatgggagaa cgcttcggcc gttattccaa gtatattatt caggaacggg cacttcctga
    49861 tattcgagat ggattgaaac ccgttcagcg tcggattctt tattcgatga ataaggatgg
    49921 caatactttt gaaaaaggtt accgtaaatc agccaaatca gttggtaata ttatggggaa
    49981 tttccaccca catggggatt cctctattta tgatgccatg gtacggatga gtcaagattg
    50041 gaagaaccgt gaaatccttg ttgaaatgca cggaaataat ggttcaatgg atggtgatcc
    50101 gcctgcggct atgcgttata cagaagctcg cttgtctgaa attgcgggtt atcttcttca
    50161 agacattgag aaaaatacgg tctcttttgc ttggaacttt gatgacacag aaaaagaacc
    50221 caccgtttta ccagcagctt ttcctaactt acttgtcaat gggtcttctg gtatttccgc
    50281 aggctatgcg acagatattc caccgcacaa tttgtcagaa gtgattgatg ctgttgtgta
    50341 tatgattgat catcccaaag ctagtttaga gaaattaatg gagtttttac caggaccaga
    50401 tttcccgaca ggaggcatta tccaaggagc tgacgaaatc aaaaaagcct acgaaacagg
    50461 taagggacgt gtcgttgttc gctctaggac agaaatcgag gaacttaaag gtggtaaaca
    50521 acaaattatt gtcactgaga ttccttatga agttaacaaa gcagtcttgg tcaaaaagat
    50581 tgacgatgtg cgtgttaaca ataaagtccc aggcatcgta gaagtacgcg atgaatctga
    50641 tcgcacaggt cttcgcatag ctattgagtt gaaaaaagag gctgatagcc aaaccattct
    50701 aaattatttg ttgaaataca cagaccttca agttaattat aattttaaca tggttgctat
    50761 tgaccacttc acaccacgtc aagtaggact tcaaaaaata ctatcaagct atatcagtca
    50821 ccgtaaagat attattattg agcggtctaa attcgataaa gccaaagctg aaaaacgcct
    50881 ccacattgtt gaaggattga ttcgtgtctt gtccatctta gatgagatta ttgctttgat
    50941 tagatcgtct gacaataagg ctgatgctaa agaaaatctg aaagtcagct atgatttctc
    51001 tgaggaacaa gcagaagcga ttgtaacctt gcagctttat cgtttaacta ataccgatat
    51061 tgttactctc caaaatgaag aaaatgattt aagagactta atcacgaccc tttccgctat
    51121 tatcggtgac gaagcaacca tgtataacgt catgaaacgt gaattaagag aggtgaaaaa
    51181 gaaattcgcc aatcctcgtt tatcagagtt acaagcagaa agtcaaatca ttgagattga
    51241 cactgccagc ttgattgcag aggaagaaac ttttgttagt gtgacacggg gcggatacct
    51301 caaaagaacc agcccacgat ccttcaatgc gtctagtttg gaagaagttg gcaagagaga
    51361 tgatgacgaa ctcatcttcg ttaaacaggc caaaacaaca gaacaccttt tgttatttac
    51421 aactttaggc aatgtcattt accggccaat ccatgaattg accgatttac gttggaagga
    51481 tatcggtgaa catttatcac aaaccatttc aaacttcgcg acagaagaag agattctcta
    51541 cgctgatatt gtgacttcct ttgaccaggg cttgtatgtg gctgtcacac aaaatggttt
    51601 tatcaaacgc tttgatcgta aagaactaag tccttggcga acttataaat ctaaatcaac
    51661 caaatatgtg aagctaaagg atgacaaaga ccgcgtggtt accttgtcac cagttattat
    51721 ggaagacctc ctattagtga ctaaaaatgg ttatgctttg cgattctcca gtcaggaagt
    51781 gcctattcaa gggttgaaat ctgctggtgt taaaggcatt aacttgaaaa acgatgacag
    51841 ccttgcctca gcctttgctg tgacaagtaa ctctttcttt gtcttaactc agaggggttc
    51901 tctcaaacgg atggctgtcg atgatattcc tcagacaagt cgtgccaatc gtggactatt
    51961 ggtcctacga gagttaaaaa ccaaacctca tagagttttt ctggccggag gcgttcaatc
    52021 agatacttca gctgagcagt ttgatttgtt cactgatata cctgaagaag aaactaatca
    52081 acaaatgctt gaagtcatta gtaagactgg tcaaacctac gagattgctt tagaaacgct
    52141 ttcgttatcg gaaagaacca gcaacggctc ctttatttca gacactattt cggatcaaga
    52201 agtactggta gctagaacac gttaaaaaga gtgaaaactc tttttaattt tatgataaat
    52261 ttagaatatt aatacaaaag aatagaataa acttgaaaat tattgaaaaa aagttacaat
    52321 agaaaaaagc agaaaagagg tacgatgatg acaatagcaa ttgattggga caacctagga
    52381 tttgaatatc ataagttgcc atttcgttac atttcttatt acaaaaatgg tcaatgggat
    52441 aaaggtcaat taacagaaga tgccacctta catatctcag aaagcgctcc agcgcttcat
    52501 tatggacaac aagcttttga aggcttaaag gcttatcgca ccaaagatgg ctctattcaa
    52561 ctatttagac cagaccgtaa tgcagtgcgt ttacaagcca cagcagaccg cttgttgatg
    52621 ccacaagtat caacagagca atttattgat gcagctaagc aagtggttaa agccaatgaa
    52681 gactttgtac caccttacgg aacaggtgca acgctttacc tgagaccgtt attaattgga
    52741 gttggagata ttattggggt taaaccagcc gaagaatata ttttcaccat ttttgccatg
    52801 ccagtaggaa actatttcaa aggtggactt gctccaacta attttattgt ttctgaagcg
    52861 tttgaccgcg ccgctcctta cggaacaggt gctgctaagg tgggaggaaa ctatgcagga
    52921 agtttgctac caggtaaggc cgctaaatca gcaggctttt ctgatgtgat ttacttagat
    52981 ccagcaaccc atactaaaat tgaagaagtc ggagctgcaa acttttttgg cattactgca
    53041 aataatgaat ttgttacgcc acttagtcca tccatcttgc catctattac gaagtattca
    53101 ctcttacaac tagctgaaga aagacttggt atgacagtaa ttgagggtga tgttccaatt
    53161 aatgaattgg ataaatttgt ggaagcagga gcttgtggaa cagcagctgt tatctctcca
    53221 attggcggta tccagtacaa ggataactta catgtctttt acagtgaaac agaagttggt
    53281 cctgtgacac gccgtttata cgatgagttg gtcggcattc aatttgggga tattgaagca
    53341 ccagaaggtt ggattgtaaa agtagattaa aatagagctt gctcttgcaa gcttttttga
    53401 ttttgtgtaa aatagacaaa gtgaggtaaa gtgatgagta aaaaagataa aaaaattgaa
    53461 atccaactga ttgatcacaa agttatggtt aatgagacta agattgatgg ctatcaatta
    53521 caaattggta aacgtgtggt tggagaaatt gcagaacttg atgagaaatt tgctgtctta
    53581 aaaaatgatg gagtagattg cttcttcaaa acgctcgaac aagcggttga aaatatcatt
    53641 gaaaactaca atttgaacca ttaaaattag acaaaaacac ttgccagctt acaaaaacta
    53701 tgatagaata gtttttgttg ttacggaaag atagcgaaga ggctaaacgc ggcggactgt
    53761 aaatccgctc cttcggg
//
LOCUS       DAUGQX010000006        53739 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUGQX010000006 DAUGQX010000000
VERSION     DAUGQX010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53739
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.006"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            585..674
                     /locus_tag="VIA51_000294"
     CDS             585..674
                     /locus_tag="VIA51_000294"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8682265.1"
                     /translation="MIIDYCNNKRIKIKLKGLSPLQYKTKSFT"
     gene            complement(712..1635)
                     /locus_tag="VIA51_000295"
     CDS             complement(712..1635)
                     /locus_tag="VIA51_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682266.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1628..2698)
                     /locus_tag="VIA51_000296"
     CDS             complement(1628..2698)
                     /locus_tag="VIA51_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682267.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2707..3633)
                     /locus_tag="VIA51_000297"
     CDS             complement(2707..3633)
                     /locus_tag="VIA51_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682268.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRFIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3633..5135)
                     /locus_tag="VIA51_000298"
     CDS             complement(3633..5135)
                     /locus_tag="VIA51_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682269.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDSFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5200..7170)
                     /locus_tag="VIA51_000299"
     CDS             complement(5200..7170)
                     /locus_tag="VIA51_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8682270.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     VKQYEKAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            7501..8733
                     /locus_tag="VIA51_000300"
     CDS             7501..8733
                     /locus_tag="VIA51_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8682271.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFAGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLYVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            8901..10082
                     /locus_tag="VIA51_000301"
     CDS             8901..10082
                     /locus_tag="VIA51_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8682272.1"
                     /translation="MTKRIILTIFTFICFSVMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRVNA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSSKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(10234..11652)
                     /gene="sufB"
                     /locus_tag="VIA51_000302"
     CDS             complement(10234..11652)
                     /gene="sufB"
                     /locus_tag="VIA51_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEQ8682273.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(11645..12124)
                     /locus_tag="VIA51_000303"
     CDS             complement(11645..12124)
                     /locus_tag="VIA51_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEQ8682274.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(12111..13337)
                     /locus_tag="VIA51_000304"
     CDS             complement(12111..13337)
                     /locus_tag="VIA51_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8682275.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATLKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(13368..14630)
                     /gene="sufD"
                     /locus_tag="VIA51_000305"
     CDS             complement(13368..14630)
                     /gene="sufD"
                     /locus_tag="VIA51_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEQ8682276.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKISANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKDAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(14725..15495)
                     /gene="sufC"
                     /locus_tag="VIA51_000306"
     CDS             complement(14725..15495)
                     /gene="sufC"
                     /locus_tag="VIA51_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEQ8682277.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(15617..16786)
                     /locus_tag="VIA51_000307"
     CDS             complement(15617..16786)
                     /locus_tag="VIA51_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEQ8682278.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(16793..17554)
                     /gene="mecA"
                     /locus_tag="VIA51_000308"
     CDS             complement(16793..17554)
                     /gene="mecA"
                     /locus_tag="VIA51_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEQ8682279.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(17700..18539)
                     /locus_tag="VIA51_000309"
     CDS             complement(17700..18539)
                     /locus_tag="VIA51_000309"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEQ8682280.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(18605..20503)
                     /locus_tag="VIA51_000310"
     CDS             complement(18605..20503)
                     /locus_tag="VIA51_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEQ8682281.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRTGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGKEPV
                     DVSTSKKNKIVALETKISRRRTLLQLLFGKVIPLVEVGFLLWQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLILNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYTK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGGGAF"
     gene            20701..22269
                     /locus_tag="VIA51_000311"
     CDS             20701..22269
                     /locus_tag="VIA51_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8682282.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            22262..23002
                     /locus_tag="VIA51_000312"
     CDS             22262..23002
                     /locus_tag="VIA51_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682283.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     ITEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            23144..23260
                     /locus_tag="VIA51_000313"
     CDS             23144..23260
                     /locus_tag="VIA51_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEQ8682284.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(23486..24496)
                     /gene="gap"
                     /locus_tag="VIA51_000314"
     CDS             complement(23486..24496)
                     /gene="gap"
                     /locus_tag="VIA51_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEQ8682285.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(24844..26922)
                     /gene="fusA"
                     /locus_tag="VIA51_000315"
     CDS             complement(24844..26922)
                     /gene="fusA"
                     /locus_tag="VIA51_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEQ8682286.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(27289..27759)
                     /gene="rpsG"
                     /locus_tag="VIA51_000316"
     CDS             complement(27289..27759)
                     /gene="rpsG"
                     /locus_tag="VIA51_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEQ8682287.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFNAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(27780..28193)
                     /gene="rpsL"
                     /locus_tag="VIA51_000317"
     CDS             complement(27780..28193)
                     /gene="rpsL"
                     /locus_tag="VIA51_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEQ8682288.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(28401..31022)
                     /locus_tag="VIA51_000318"
     CDS             complement(28401..31022)
                     /locus_tag="VIA51_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEQ8682289.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKHNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESK"
     gene            complement(31013..31852)
                     /gene="purR"
                     /locus_tag="VIA51_000319"
     CDS             complement(31013..31852)
                     /gene="purR"
                     /locus_tag="VIA51_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEQ8682290.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(32119..33057)
                     /locus_tag="VIA51_000320"
     CDS             complement(32119..33057)
                     /locus_tag="VIA51_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEQ8682291.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(33047..34318)
                     /locus_tag="VIA51_000321"
     CDS             complement(33047..34318)
                     /locus_tag="VIA51_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEQ8682292.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQAGLYQQLTDIRDVLHRSLSDSRDRSDKRLEKINQ
                     QVNQSLKNMQESNEKRLEKMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNASFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            complement(34320..34952)
                     /locus_tag="VIA51_000322"
     CDS             complement(34320..34952)
                     /locus_tag="VIA51_000322"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEQ8682293.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(34945..35607)
                     /locus_tag="VIA51_000323"
     CDS             complement(34945..35607)
                     /locus_tag="VIA51_000323"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEQ8682294.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(35617..36489)
                     /gene="rsgA"
                     /locus_tag="VIA51_000324"
     CDS             complement(35617..36489)
                     /gene="rsgA"
                     /locus_tag="VIA51_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEQ8682295.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALEIGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(36913..37785)
                     /gene="rsmA"
                     /locus_tag="VIA51_000325"
     CDS             complement(36913..37785)
                     /gene="rsmA"
                     /locus_tag="VIA51_000325"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEQ8682296.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMVFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(37899..38489)
                     /gene="rnmV"
                     /locus_tag="VIA51_000326"
     CDS             complement(37899..38489)
                     /gene="rnmV"
                     /locus_tag="VIA51_000326"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEQ8682297.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(38461..39252)
                     /locus_tag="VIA51_000327"
     CDS             complement(38461..39252)
                     /locus_tag="VIA51_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEQ8682298.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD"
     gene            39537..40367
                     /locus_tag="VIA51_000328"
     CDS             39537..40367
                     /locus_tag="VIA51_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEQ8682299.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDSSERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            complement(40478..41416)
                     /locus_tag="VIA51_000329"
     CDS             complement(40478..41416)
                     /locus_tag="VIA51_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8682300.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDEGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVVLAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(41438..42352)
                     /locus_tag="VIA51_000330"
     CDS             complement(41438..42352)
                     /locus_tag="VIA51_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEQ8682301.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGNISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIADKDLEKAKALQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(42364..43026)
                     /locus_tag="VIA51_000331"
     CDS             complement(42364..43026)
                     /locus_tag="VIA51_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEQ8682302.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKYYFKSGLRLGLIELGIMTICLLDLF
                     LIRNQSGLVFQGFKVLCVAVLFLVVILFLYAYPQAVKRDLSLSTLFKRSFLLAGLFFP
                     WSFAFLAFICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(43183..44013)
                     /locus_tag="VIA51_000332"
     CDS             complement(43183..44013)
                     /locus_tag="VIA51_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8682303.1"
                     /translation="MTKKKLTASDILTTVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(44026..44913)
                     /locus_tag="VIA51_000333"
     CDS             complement(44026..44913)
                     /locus_tag="VIA51_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8682304.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTEFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(45016..46335)
                     /locus_tag="VIA51_000334"
     CDS             complement(45016..46335)
                     /locus_tag="VIA51_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8682305.1"
                     /translation="MNMKKLASLAMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(46384..47088)
                     /locus_tag="VIA51_000335"
     CDS             complement(46384..47088)
                     /locus_tag="VIA51_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEQ8682306.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLMAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            complement(47362..47496)
                     /gene="rpmH"
                     /locus_tag="VIA51_000336"
     CDS             complement(47362..47496)
                     /gene="rpmH"
                     /locus_tag="VIA51_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEQ8682307.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(47811..48725)
                     /locus_tag="VIA51_000337"
     CDS             complement(47811..48725)
                     /locus_tag="VIA51_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEQ8682308.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINRQNTPAVNSADVEPEEIKATQRLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(48737..49564)
                     /locus_tag="VIA51_000338"
     CDS             complement(48737..49564)
                     /locus_tag="VIA51_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8682309.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQRKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(49530..49889)
                     /gene="rnpA"
                     /locus_tag="VIA51_000339"
     CDS             complement(49530..49889)
                     /gene="rnpA"
                     /locus_tag="VIA51_000339"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEQ8682310.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            complement(50429..51169)
                     /locus_tag="VIA51_000340"
     CDS             complement(50429..51169)
                     /locus_tag="VIA51_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682311.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(51173..52456)
                     /locus_tag="VIA51_000341"
     CDS             complement(51173..52456)
                     /locus_tag="VIA51_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8682312.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSIIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            complement(52453..53739)
                     /locus_tag="VIA51_000342"
     CDS             complement(52453..53739)
                     /locus_tag="VIA51_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8682313.1"
                     /translation="MYIFSFLSDITLPVWKQLTILALALFFNQFPYLSPLLIDPLLFL
                     VVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVIPYLFLSSGIYLGHIIFDLLA
                     YLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTLLIFVLVYYVDIFVILGFTDP
                     FLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKEYLKNELRREQQAYMTNLEIY
                     GKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQDIYAQTVHEANDYWDDKHYN
                     ISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNIKETYIPELDLLLLMSIFCDN
                     AIEAALEAQQPHMSIAYFLLGDYQMFVVTNTTKKKVDINKIFEEGYSSKGSERGIGLS
                     NAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
BASE COUNT        16349 a        11258 c         9759 g        16373 t
ORIGIN      
        1 actttttttg tactttttta tttgcccgcg ttgtaaaatg aagtgcaaca aaaaagagaa
       61 aaagccttga actacacccc aaacgttaga caaaaaaatc taacgttcgg ggtatttttt
      121 atgaaattaa gtgatgaaag tacgaaatag acatcgttaa gaaagaaaaa aatatctact
      181 atccaccaga gataaagcaa gaaataatgg ataacgtttt gatagaaggc ccgccacaat
      241 accaagtatc acttgtttat ggcttgttac atgcaggaac tctcccaagt tgaatagcac
      301 aatataagaa aaacagttat actgttgaga aaacaagagc aagaccatca caaacaggac
      361 gtaaaccaaa agaaacctga agaaatgact aaattagagc ggcttcaaga agaaaatgaa
      421 tatctcagaa ctgaggttgc ttacttaaaa aaaccgagga actccgtttg aaagaagcat
      481 ctctgcaaag aagaagacaa aaaaaccatt ataaaaaatg gacaaagacg agttctgatt
      541 agattttctt ttaagaacgg ctgtattgac tcgttctacc tactattatc atcgattatt
      601 gcaacaataa acgtatcaaa ataaaactaa aaggacttag tcctctacaa tacaaaacta
      661 aatcctttac ttaaaataga gtagccaact tttggggtca gtgcatctct tttacaattc
      721 tttttgatat ttttcaattt ctgcttggtt tgcccaaaca aagtgatttg gtttgatttc
      781 aaccattgat ggcttatcta atgtataatc atgttggtct ggatgataga caacaagttc
      841 tttttgacgc tctaaaattg gatctgggat aggcacggct gataacaaag attgggtgta
      901 gggatgaatt gggttattaa acagttcttc tgtttctgca acttctacaa taaccccttt
      961 atggataacc gcaatacgat ctgaaataaa gcgaacgact gaaagatcat gggcaatgaa
     1021 gagataagtc aaaccttttt cggcttgcat tcttttaaga agattcaaga cctgtgcgcg
     1081 aacggaaacg tccaaagctg aaatcggttc atcagcaata acgaattcag ggttcattac
     1141 tagggctcta gcgataccga tccgctgacg ttgacctcct gaaaattcat gagggtagcg
     1201 cgtcaaatgc tctgatagca aaccaacttc ggccatcatg ttcttaattt tttctttacg
     1261 ttcttcctct gttttaaaca gattaaagtt ataaagacct tctgaaatga tgtagtcaac
     1321 ggttgcccgt tcattcaaac tagcagcggg atcttggaaa atcatttgaa ttttacgaat
     1381 gagctcattg gcttctgatt ttgattttct gccattaatt actttcccat cgtataaaat
     1441 ttgacctgaa ctagtatcgt tcaaaccaat aatagcacga ccaattgttg ttttaccact
     1501 cccagattct ccaactaaag aaaaggtttc tcctttttta ataaagaaat tagcattttt
     1561 aactgcaaca aattttttct ttccttctcc gaaggaaatt tctaggtctt ttacttcgac
     1621 taatttctca gacatttcct tcctcctgtt gtgacatttt tcttaagatt ttttgatgca
     1681 aatcttgaat gacttctggt ttttgaactt ttggagcctc tgggtgtaaa agccatgttt
     1741 tggcccaatg agtctcagat acgttaatcg ccggaggtgc tttttcaaag tctaaaacca
     1801 tagcatattc tgagcgaagt gcaaaggcat ctccgataat tggtgaataa agtgatggag
     1861 gcgttcctgg aatagcgtaa agttcaccag attcatctgc caactgcggt aagctagaca
     1921 gcaaactcca tgtatagggg tgtcttggat catagaaaat ctcttcgact gttccaaatt
     1981 caacaatttc tcctgcatac atgacagcca ctttatctgc aatgcttgcc acaacaccta
     2041 aatcgtgcgt aataaagata atggtgaaat gatattctcg ttgaagcgac ttcaataact
     2101 caacgatttg agcttgaata gtcacatcaa gggctgttgt tggctcatca cagataagaa
     2161 tatctgggcg acaagctaaa gcaatagcga taacaatacg ttgacgcatt cctcctgaat
     2221 actcaaatgg gtaatcttca aagcgttttt tggcatttgg gatacccact ttattcatgt
     2281 aatcaagggc catttcttta gctttggcat gacttacttt ttggtgctta ataatcactt
     2341 ctgtgatttg gctaccgata gttttaatgg gactaagact ggtcattggg tcttggaaaa
     2401 tcgttgcgat ttttgagccg cgaatctttg cccactcttt atttgttttt aaatctgtca
     2461 attcttgccc acgatagaca attgaaccat tagcaatgcg tccattagac tccaacatcc
     2521 ctgtaaaggt ctttgttaaa acagatttac ctgagcctga ttcccctaca aaagcaagga
     2581 cttctccttc aacaagttcc agtgagacgt tacggatagc tgttaaaaca cgatcacgca
     2641 catcaaattc taccaccaca tctttggcag ttaagattac attattttct tttgtcattt
     2701 taactcctat ctatgtgaac gtgggtcact ggcatcagcc aagttttgtc cgacaatgta
     2761 tagtggtaac gatactaaaa tcaatgttac taagggaatc caaaagaggt aggcatttgt
     2821 tgttaagttg cttgaataat tagcaataaa acgtcctaaa cttggagtgg tggttggtaa
     2881 accaatccca aagaaggata agaaggcctc agaagataca taaactggta gcatttgtga
     2941 caacatagtc atgataactg aaaccaattg aggcaggagg ttcttaacag caatcttgta
     3001 cattggtgtt cccaaagttt gactagcaag gttgtattct aaatcacggt aacgcaagat
     3061 ttgaacacgg atggagtagg cgacaccaat ccatccagtg atacagaaag ctagaatcaa
     3121 attccaaaat cctgcaccta atgaataggt caaaacaatg ataataagca tagaagggat
     3181 atttgagata atgttataaa tttcaatcat aactttatca aatgctttag aaactcccca
     3241 tatggctcct aacactaccc caatggtgat attaattagt gtcgctataa ctgagattaa
     3301 aatagaatta cgtgccccat accaaacacc atcaaacaga gattgcccat ttttgtcggt
     3361 tccaaaccag tactctgcat ttggccaaat ataacgcttt gaaaagtcat tgatattact
     3421 aacgtcatta aagtcgtagt tggcaaacat tggataaata aagctcatca tcaagactgt
     3481 cactaaaatt acgagcataa agactgtaga ttttttagaa aaaaactgac gaaacactga
     3541 tttccagtaa gaataagcag gggtatcaat cacttcggag gcttcactat cgcgctcaac
     3601 aaatcgaaat ttagatttat caatcgattc cattacttac ctcctttttt tgttgacaat
     3661 ttaatacgtg gatcgacaag ggtcatgaca atatctccta gtaaaagtga aacaattgac
     3721 aagacagtga agataaaggt taatccaaca atcatagaat tgttagcaga tttaatagaa
     3781 tcaattaaca ttttacccat acccgggaag gcaaagacag tctctgttaa tgttgcacca
     3841 ccaatagcaa ggataatact tgcaggaacc cctgacacaa ttgggaccat ggcatttttg
     3901 aagagatgcc ctctgtaaat ttcagattct gataatcctt ttgaacgcgc aaaacgtacc
     3961 caatcgctgg cctgaaggtc aacaagatag cgacggaacc agataaccgt agttggaata
     4021 tttaaaattc ctaaaataag ggctggtaaa atataagatt taggatcaga tgcccccagc
     4081 attgggaaac tatctggtaa accaaccatg ccacctagga agcgaacaac atagataaca
     4141 gcaatacttg gtaaagcaag catgaaggtc atggtcgctg ttgagaaact gtcaaaatag
     4201 gtatttttaa accgagccat aaataaacca agaggcaaac caacgatata ggaaaacata
     4261 acaccaaaaa aaccaattac aaaagaattg tgaatcattg atgggtcgac ataattattg
     4321 atggttttag tgtaggaatc tcccttacca tagtttacct tggtgatatc atccaatgat
     4381 tttggatttt tgtagctacg gctatagata tccactgacg atttcttagt gacacctgat
     4441 gggaaggtca catcttgaag agctgttcgt ccttgccctt gtgaaatgac ctgaagaaca
     4501 ggaatattgc tgtatgttgg ataagatgtc cctaagttta aggtaacaaa gttttggtga
     4561 agataaggaa attttccgtt agtatagagg agatacttat gttttgtccc cgaaccaaca
     4621 agtgaccagc caactgattt atctttttct agacgaatat acctagctaa ttttggatta
     4681 tctttatcct gaatcttcca agggtgatca ataacaacta gatttgagaa aaagttccaa
     4741 acacgttcgt aaatagggat attgcgaatt gcataaaact gtttgctagt ggggaagcgt
     4801 tttagctgcc agccattgcc aagagaatca atatacttct catagatagc tttgttagca
     4861 ctagttgctt ctgtcgttac actactatct actttagaag cattatcttt taattctttg
     4921 cttgaaaaat aattgacata acccatacgt tgaaaagtta gattttcata cgctactttt
     4981 ttatctggtg ttgttgtcat tttattataa ttagggtctt gtttaaagat aaggctggta
     5041 ggtactagag tatatacgat ggtgtatgtt aaagccgtta ccagaactac cgacactaac
     5101 gatcgcatga tacggtttaa aatatatttt ttcatagttg tcctcaatag ttcaaaagaa
     5161 ctccctcaca taaacgagaa agttcttttg aacatcgttt tatttttcaa cgtgatcagc
     5221 taacttctca gcatattttg catttgactt agcctttgct ttcatccatt tttcttttgc
     5281 tttttcgtat tgttttactg tgacaggttt gtcttgaagt ttcattcctt tatatgctag
     5341 aggaccttta gaccctgccc aagagaagcc cccgctaaat ggaacggctt tagtaactcg
     5401 tggagtgcca cccaatgcca caactggaat atctacggca ttatctgtaa ggtaggcttg
     5461 tgcttttgcg taagctttat agcgcgcatc gttgtcgtct gtaattgctg ctgcttcatc
     5521 aagaagagtt tggtaggtat caaggcctgc agctgccaca acatccttat tttgacctgc
     5581 tttgattcca agtttttgga taacagatcc accacctact ggactcatga tgtcaaggta
     5641 ggtccgtgga tcttgatagt ctggtcccca ccatgatgaa atgatatcgt agtcttgttg
     5701 ttctggggtc tcagcataga agccttgggc ttcgtgagtt gatgtttctg tttcaagaac
     5761 attgacaatg acattctctt taccaagaga tgcttcaaca gattgtttga aagactgggc
     5821 ttcctgaaca gttgctgcgt ttgcttggtc aacagggtaa tctaattgaa ctgggaaggt
     5881 tacaccttca gctgttaaag cttctttggc ttttgcaaac tcagcttttg ctttttcagg
     5941 attatagaaa ccatcttgag catcagctaa gttaacgtct ttccattcat ccccaagttt
     6001 tgccatttcc ttttcaactt ctgaaccaaa atcactttct ccaatggtca caaatgttgg
     6061 tgggacaagc atgttacgta aggcttttgt tttggcatct tgacctgcag tttgtgcttg
     6121 gaatgacgct cggtcaaaag caaactgaat agcttgacga aaatccttgt tgttaagagc
     6181 tttcttaccg gcatcttgtt gtgcagggtc tttcttagtg tttttgaaag aagtacggtt
     6241 caaattccat gttaaatgac ggatatctcc agtcaacatt ccgtaagtaa tgttatcagc
     6301 atagtttttc ttagctgatt tgtaggtagg gtcatttggg taaagtcgtg caacgctgaa
     6361 ctcacccttg tcaaagttct tgtagaacga acctgggtct gaaccatctg agtaagtcaa
     6421 tttaacagat tctatcccaa cattcttagc atcccagtag ttttcatttt tatggaattc
     6481 catagatgat tttgaggtga aggcgctcaa gaagtaagca ccattaacaa ggattgatga
     6541 tggatcggtt gtaccaaaat ctttaccttt tgacttcaaa aatttcgcat taactgggaa
     6601 aagcacacta taagttgttt ttgaattcca gtagctttca ggcttgttca aagtatactg
     6661 aacagtttta tcgtcaaggg ctttgacacc aacttcttta aaatctactt caccattttg
     6721 gtaagccttt aagtttttta ttgaatcttc aacaacgtaa agagcatctg atttatcgtc
     6781 aaccgcgtgc ttcaaaccag tcacaaaatc ttctgctgtt actggggcat attcttcacc
     6841 atcagccgta taccaagaga caccatcgcg aagagtataa gtataagtca gaccgtcttt
     6901 tgaaaccttc caatctttag caagtgatgg tactaaatta ccatactcat cgttttccaa
     6961 aagaccatca accatttgtg ttatcacatc agtcgttcca ccgccattag tcaaaatata
     7021 atccaatgat tttggatcgt taacaaaaac gtacttgtag gtttttgtag cttctgagcc
     7081 acctgaagca tttttattac cacaagctgc caaagcggat actgacaaga tcgcaacact
     7141 tacagctgcc aaccatttac ttttcttcat aaaagtcacc cctaaacttt atttttcatt
     7201 ttttggcaat tgctaaatga aattggttaa ttgaagacat tatatcataa aactttctta
     7261 aagaaaataa tgaaatgaaa aattatctga atatttcgta gaattttctt tattttatac
     7321 atttatctat atgaaagcgt tacactcctt ttttaatgag gtttcaatta gtttaataaa
     7381 gattgtcatt ctctcatggt agcgttttat tacatcacta ctcttgtgag gtaagtcatt
     7441 accttagaca aaaatatggt ataattaaaa aaataatact tgagtaagga taatctataa
     7501 atgatcaaac gattaatttc cctagtggtc atcgccttat tttttgcagc aagcactgtt
     7561 agcggtgaag agtattcggt aactgctaag catgcgattg ccgttgacct tgaaagtggc
     7621 aaagttttat acgaaaaaga tgctaaagaa gttgtcccag tcgcctcagt cagtaagctc
     7681 ttgacaacct atctggttta caaagaagtt tctaagggca agctaaattg ggatagtcct
     7741 gtaactattt ctaactaccc ttatgaactc actacaaact atactattag taacgttcct
     7801 cttgataaga gaaaatatac cgttaaagaa cttttaagtg cgttagttgt taataacgcc
     7861 aatagccccg ctattgcttt agctgaaaaa ataggcggaa ccgaacccaa atttgttgac
     7921 aaaatgaaaa aacaattaag acaatggggc atttccgatg caaaggtcgt caattcaact
     7981 ggcttaacta accatttttt aggagctaat acttatccta atacagaacc agatgatgaa
     8041 aattgttttt gcgccactga tttagctatt attgccaggc atctcttatt agaatttcca
     8101 gaagtactga aattatctag caaatcctcc actatttttg ctggacaaac catttacagt
     8161 tataattaca tgcttaaagg catgccttgt tatcgagaag gcgtggatgg tctttttgtt
     8221 ggttattcta aaaaagccgg tgcttctttt gtagctacta gtgtcgaaaa tcaaatgagg
     8281 gttattacag tagttttaaa tgctgatcaa agccacgagg atgatttagc tatatttaaa
     8341 acaaccaatc aattgttgca gtacctttta attaattttc aaaaagtcca gttaattgaa
     8401 aataataaac cagtaaaaac gttatatgtc ttagacagtc ctgaaaaaac tgtcaaactt
     8461 gtagcccaaa atagtttatt ttttatcaaa ccaatacata caaagaccaa aaataccgtc
     8521 catattacta agaaatcatc cacaatgatc gcacctctat caaagggaca agtcttaggt
     8581 agagcaaccc ttcaagataa acatcttatt ggacaaggtt atctggatac tcctccttct
     8641 atcaatctta tccttcaaaa aaacatttct aaaagtttct ttttaaaggt ctggtggaac
     8701 cgttttgtga ggtatgtcaa tacctcttta tagaataaca caatgctttt tgtatgacat
     8761 tgactgacag agtacttctg cagtcttttt catttttatt taagcaaact aggccaatcc
     8821 taacaatttt tcaaaaaaac ttcacattgt attagcaaag tgatatactg aaaatgcatt
     8881 acatttaaag gagtcggaaa ttgaccaaaa gaattatact aactattttt acctttattt
     8941 gcttttcggt gatgcctctt gtccacgccg aagatgtcat ggatattaca aggcaagcag
     9001 gctacacagt tagtgaggtt aatcgaccaa aatcttctat tgtcgttgat gcaaatagtt
     9061 cagatattct ttggcaagat aatattgata ttcctaggga tcctgctagt atgtctaaga
     9121 tgtttacgct ttacatttta tttgaagagc tcgctaaggg aaaaattacg atggacacta
     9181 ctattacggc aactccaacc gatcaagcta tcgctaacat ttatgagatt agcaataata
     9241 atatcgtcgc tggagtagct tatcctattc gtgatcttat tactatgaca gctgtgcctt
     9301 catcaaatgc agcaactgtt atgattgcca attatttatc aaacaatgat gcttctgcgt
     9361 ttatcgatcg tgttaatgcc acagccaaac aattaggcat gactaacact catttttcaa
     9421 acgctagtgg tgcagcagca caagcttttc aaggttatta taatcctact aaatatgatt
     9481 tatctgcttc aaatattacg accgctcgag atttgtccaa gttactctat gccttcttaa
     9541 aaaaataccc tgaaattatc tcctttacaa ataaatctgt tgtgcacact atggtaggaa
     9601 cgccatatga agaagaattt cacacctata accactctct cccagataat caatttggta
     9661 tgaaaggagt tgatggatta aaaacaggtt ctagtcccag tgctgctttt aacgccatga
     9721 taactgccaa aagaggcaaa actcgactca ttactattgt catgggggtc ggagattggt
     9781 cagatcaaaa cggggagttt tatagacatc ctttcgtcaa tgccttgact gagaaagggt
     9841 ttaaagatag taagacctta tccaaaaaag cacgccaaaa actcgaaaaa ttagtgccac
     9901 aaaccaaaaa agaaacatca tctaaacagc agcacttcaa agccactaaa aagcaatcgt
     9961 acttggaaag agtcgaagat tttatgaatc acaaccacac tttcttgctt atttgcttag
    10021 ctatctttat aattactatc cttttactaa gcctcgttgt ctttgcaatg ggacgccaat
    10081 aatgaattat caaaaacctc tgtcaaagca cagaggtttt tgatatgtta tcttacgtgt
    10141 tcaaggcaac taaaaactaa ccacttgggg ttagtactac aactcataaa atcctatctc
    10201 aaagatcttt cagatggata agagaaaatg caattaaccg acagaacctt ccatctcata
    10261 ggaaatcaat cgattgagtt cgaccgcgta ttccattggc aattctttgg taaaaggctc
    10321 cacaaatccc atgacaatca tctctgtggc ttcgctttct gataagccac ggctcatgag
    10381 atagtagagt tgttcttcag aaatcttaga cactttggct tcatgttcta acgccacctg
    10441 tgaattatga atttcgttaa atgggattgt atctgattta gaaatatcgt ccatcaaaat
    10501 agtatcacat tcaatatggg aaacggattt tttagattgc ttgttaaagg tcacttggcc
    10561 acgataatct actttaccac cagacttggc aattgatttt gacacaattg atgatgatgt
    10621 atgtggagca ttgtgaatca ttttagcccc tgtatcttgg tgttgacctg cattagcaaa
    10681 ggcaatagac agcatggtgc cacgcgcacc tggcccatca agataaacag aagggtactt
    10741 catggtggtt ttagctccta gattgccatc aatccattcc actgttgcat ccgtaagggc
    10801 gcgtgcacgt tttgttacta gattatacac attgtctgac cagttttgaa tggtggtata
    10861 acgcatgtat gcaccatcaa gcgcaaagat ttcaacgata gcagcatgta agctgttact
    10921 tgaataagtg ggagctgtac atccttcaac ataatgaaca cttgctcctt catcaacaat
    10981 aatcaatgtc cgctcaaatt gaccagtatt ttcattgtta atgcggaaat aagtttgcaa
    11041 agggatatct accttgaccc ctttaggaac ataaataaag gtaccaccag accaagctgc
    11101 tgaattaagg gctgctaatt tgttgtctgt tggcggaacc agtttggcaa agtattgttt
    11161 gaacaaatca ggatattctt tgagggcgga atcggtatct gtaaagataa tccctagctt
    11221 ttcaaattca cccttcatgt tatggtaaac cacttctgac tcatactgag ctgatgcccc
    11281 agcaagataa gcacgttctg cttctggaat tccaatacga tcaaaggttt cttttatttt
    11341 ttctggaaca tcatcccaag aacgagctgg cttatcagat gctttttgat agtaaatgat
    11401 atcatcaaag ttaatatctg ataagtctgc tccccaggtt tgcatcggca ttttattaaa
    11461 ggtttccaag gattttaaac gaaactccaa catccactca ggttcatttt tggcagctga
    11521 tagttcgcga accactgcct cactcaatcc ttttcctgta gaataaatgg gctctacatc
    11581 atcgtgaaat ccaaattggt agtcccctaa gtcaattggc tttggctcta ctttctcatt
    11641 tatatcagac atttttccct tcctttacat tttggtccgt gaggtgctga gcattggcac
    11701 ttcgtttaat ggcttccttg agagcattcc aagctagggt agagcatttg atacgctgtg
    11761 gaaattttgc aactcctgcc aacaattctg cttcacctag ctctttttga gcaggatttt
    11821 cctgtccttg taccatctct gaaaaaatat cagctaacgc gagtgcttct tctttacttt
    11881 taccaataac agcatctgtc atcatgcttg atgaagctgt ggaaatggta cagccgttgc
    11941 ctgcaaaagc aatatcttca attttatctt cgtcaaactt aacggtcaaa gaaatcacat
    12001 caccacaagt cggattattc agttgaacag cctctacgcc atctagttgc ccatgatgat
    12061 gtggacgttt cgaatggtcc gctaccacag ccatgtatag atggttcagt ttagagagtg
    12121 ccattgaaaa actcctttgc ttttagaatt gcttcgacta gacggtcaca atctgccttg
    12181 gtgttataga tataaaaact tgctctaaca gttgctggta cacctaaata actaagaaga
    12241 ggttgggcgc agtggtgccc tgctcttact gcaacacctt catagtccaa ggctgttgcc
    12301 aagtcatgag gatgcaaatc atccagatta aaagaaatca gaccagatct tgcactaggc
    12361 tggcttggtc catatatggt aagcccctca atagcttcta atttcggcaa gacataggct
    12421 attagttctg cttcatgcgc atgtatatca gccatgccta gtctctgaag gtaagaaatg
    12481 gctgcgctta gcccaatagc accagctatg tgaggtgttc ctgcttcaaa cttccagggc
    12541 aattctttcc aagtggcctc ttgttcgtaa acaaaatcaa tcatttctcc gccaaattca
    12601 agaggctcca cttgattcaa aagctcttct ttgccgtaaa gaacacccaa acctgttggc
    12661 cccaacatct tatgagctga aaaagcaaag aaatcacaat ccaagtcttg aacatcaata
    12721 gccaaatgtg gaaccgactg ggcaccgtca acaacaaggt aggctccttt agcatgtgcc
    12781 agcttggcaa tttctttaat gggattgatg caaccaagaa cattggagac atgtactagg
    12841 ctaacaaaac gtgtttttgt cgtcaatttg tttgccaaat cgtccatgtc aagttggcca
    12901 tcttttaaat aaacatagac taaccttgct cctgtttttt gacaggcttg ttgccaagga
    12961 atgatattgg catgatgctc cataatcgaa atcaacacct catcttctgg cgtcaagacc
    13021 tgctctgcaa accgagcaac ccaattcaaa ctggttgttg ttcctctggt aaagagcact
    13081 tccttacttg atttagcatg aataaagtca gcaacctgct ggcgactggc ctcatatttg
    13141 agcgttgcac gttcagccaa ggtatgaact cctcggtgga cattagcatt atcttcttga
    13201 taataggatt gcaaagcctc aagaacaagc gccggttttt gtgtggtggc ggcattatcc
    13261 aaataaacaa ggggttcatc attgacttgt tgatttaaga tttgaaagtc ttgtttaatg
    13321 tcttttgcgt ctagcaatac taacctcttt ctttttggca gtaggtctta acgattaagc
    13381 aatttctcat ctaaaacctt aataatctct tggcggactg atggaatagg aatttcagcg
    13441 ataaccgctc ctaggaatcc tctaataacc aatcgttctg ctgtttcttg atccagtcct
    13501 cgactcatca agtaatacat atcttcaggg tcaacctgac cgatagaagc tgcatgacct
    13561 gctgttactt cattttcatc aattaagagg attggattgg catcggctct tgcttggtca
    13621 gaaagcatca aaacacggct ttcttgttga gcatcagctc ccttagcgtc ttttagaata
    13681 tgaccaatcc cgttaaacgt taaggtgcca cgttccaaaa tcacaccatg ctgtaaaata
    13741 tgaccgaccg tacgttgacc atagttggtc acgcgcgtgt caataccttg tacctgacga
    13801 ccacttgagg ctgcaacaac tttcaaatca gcttgtgagc cctgaccaat caaatcactg
    13861 tcaaaatcag caatgacatt gccttcattc atcacagcta aggcccaatc aatgttggca
    13921 tccttctcta aacgtcctcg acggctaata taggttgtca ctgaaggacc taagcggtcg
    13981 atagccgaga atttaatctg gctgcctgct tgagcaatca cttctacact gatattagcg
    14041 ctgatctttt gagtggcatt gccaatagat tcaaaacgct ctaaataggt gaacttactt
    14101 tcttttcctg caatcactag aacatgcttg ttaaaaggaa cgtcactgtc actatcttgt
    14161 aagaaaatag cttcaatagg agttgtgatt tccaagtgat caggaacgta gagcacggct
    14221 gcgctattaa aataagcagt gtggtaggca gctagtttgt cttcatcaaa agctaatgcc
    14281 tgaccaaaat gagcttcaat tacttctggg atttcctcaa gcgccgtata aaaatcactg
    14341 aaaacaactc ccttgtcaat taacgccatt ggtaactgtt ctaagactgt ttgcgtgcct
    14401 acctgaacaa gctttgggtt atctccaata gctataaaat ctggaacact agctagactt
    14461 tcattttctg ttaaggtacc atctcctaga ttccaacggt gaaatttaac cctttcgatg
    14521 gttggtaatt ccaaatttgg aatggcttct aatgccgcta aacgccgttc ttgcagccaa
    14581 gcaggctcag cgtgggcttg cgaaaaagcc actagttttt cttttgtcat ctgtcaatcc
    14641 tttgtctctg gtttttaaat tggctgggta tatagaacat cacctagctt tttgtagaaa
    14701 gctaaagtaa ttgtctccaa aaacttaact ttcttcctta tactcgattc ccagatcctg
    14761 tgcaatacct gcgtagcctt ctttttcaag acgagtagcc aaggcagcat caccagataa
    14821 gacaatacga ccatccatca taacatgaac taggtctggg gtaatgtaat tcaacaaacg
    14881 ttgatagtgg gtgataatca tagctccaaa gtctttccca cgcatctcat taaccccttt
    14941 agagactact tttagggcat caatatcaag accagaatca atctcatcta acaaagcaaa
    15001 tttaggctct aacatgagca attgaagaat ttcattgcgt tttttctccc caccagaaaa
    15061 accttcattg aggtaacgct ctgccatctc ttctttcata cctaacaaag ccattttctc
    15121 atcaagtttg gtgataaaat ctcgcacgga aatcttatcc tcatctgcct taccggcatt
    15181 cattgctgca cgcataaatt cagcgttggt aatccctgga atttctgaag ggtattgcat
    15241 ggcgagaaaa agtcccagtc tcgcacgctc atcaacttct agatcgagaa tattgacccc
    15301 gtcaagcaaa atttgccctt gggtcacttc gtagttagga tttcccataa tagctgctga
    15361 aagggtagac tttcctgtcc catttggccc cataatggca gctacttccc cagttttaag
    15421 agttaggtta acccctttca aaatctcttt accttctatt gaaacatgta aattattaat
    15481 ctcaagaatt gacatgatac accccttatt ttctctgtca tctataccat ctcaagaaaa
    15541 gacagtgtca tttgcactgc tttttttata atggtcactg catctattat agcaaaaaaa
    15601 gccttactcg gcttttttag tgtttcaaat ccttcttttc tttccatttc agaagcattg
    15661 cttgacgata atcactatta ccaataaact ttaacaagtt aaacaaaggc gttcgctttt
    15721 caccccagat ctccaatcct tcaataaaaa cttctaaacc aaataaaagt ccaagcatca
    15781 agaggacgcc accaattcga ctagaaacat ttaaaagtaa agaaataagg gaaaaaagca
    15841 tggtaatacc ataaactact aagacagctc ctcgatgagt aaagcccatt gataagagtc
    15901 gatgatgcag gtgcatctta tccggctcgt agaatttttg acctgataaa ctacgtcgaa
    15961 taatagccac gatggtatcc ataatgggta caccaagaat aataacaggt gtcaccacag
    16021 ccacagccgt tgaatttttc aatccttgaa gagacaaaac ccctatcata aagccaataa
    16081 agagggctcc tgtgtcaccc aaataaatca tagctggatg gtaattataa ggaaaaaatc
    16141 ctgcaatagc agaaatcaag accaaaatgg ttaacgtcaa aaagaaatcc ttttgaggta
    16201 aaaagaaata agatacaata gccatggtca ctaaactaat aatagagacc ccactaacca
    16261 aaccatccaa accgtcaatc aagttaatag cattagtgat ggaaacaatc cacaggactg
    16321 ttaagaataa ggttaagaaa ggaccaaaaa ctaacaacgg ccctccaaaa ggaattttga
    16381 agctatcaaa tttaaagtcg gtaaaagccc agacaatcac tgcaccaatt agaataccaa
    16441 acatctttaa tttaggactt aactcataca aatcatctaa aaaaccagta agggtaatta
    16501 ctgtagcacc aatcacgaca ggtaaaatat aactgaagta ggtctgacca aaaaacatgg
    16561 cgcctttaga agcaatcgga ataagtccca aacttgctac taaaaaagac ataaaaatag
    16621 ctaatccacc actggttggc atcggaacct tattgacccg tctggcattg ggattgtcta
    16681 ctgcacccac acgaaaggct aaaaagcgaa caagaggggt taagaataag gacattaaca
    16741 aagcccctat cagaacaagg acataatcta ttgtgaatga aaacatacta ttttatccca
    16801 actcaatctt ttgtaattgc tcaacagcac catcaagcat caattgtaag ccatgctctt
    16861 gtaaataagc tcttgttttt gatccagggt ttgcatgctc aatcaatctc gcatacatga
    16921 cgttcgcaaa ataagatggt tgttgctgaa catctaataa aatagtcata tggtagcagt
    16981 tgctcccctt atataactct gaagcttcta tcgaaaaatc aatcgtttta gcaaaagcca
    17041 ctgcctctgt aatcgttgaa aaatccaata cataatggac atagtctaaa ggttctgact
    17101 catgattagt tgatggatca gccgcctcag actgattagc tagagtggct tcaacaacat
    17161 cttccattat ctcttcaatt ttttccaatt tttcatgagc tttgacatct cccttttcac
    17221 gcatggattg ctccaagctc ttgaaaaaat cttccggagt catttgggac atatcaccaa
    17281 actctgctaa atcttcaaga ttaatatctt tatttatctc agatttggta acaaaaacat
    17341 ctagacggtc cttgcgtgga gtcactcgaa aactaagcat accactatct ttaaaattat
    17401 ctggaagatc gagttcgtcc atcacagaat agaaaaactc ttctgttttt tcttgaggaa
    17461 tcaagaaatc tttcaactcc attcctcttt cttctaaatc gtccatacta attgttattt
    17521 ttagcgttgt ctcgctaatt tgtttcattt ccattctcaa tacctcgcac gcgtagtcat
    17581 tttattatac tagaaatgct gtaatttcgc aatttatgac taactcctcg tctacaaaag
    17641 gaaatttaaa aagcgacagt ccccaaggtc tgtcgcaaca tcctaaacga tatgtaagtt
    17701 taaaaaacaa atttaaagaa gctataaata agtaaaaggc ttcctaacac aatacggtat
    17761 ttcccaaaaa tggtgaaatc gtgtttctta acataatctg tcaagaacct aatcgccaat
    17821 aaactaacca caaaagcggt caagctagcc actaaaagaa taaggacttg tgcaaaatca
    17881 aggtgatggc catcaaggaa aaattttaca gcctttaatc cactatatcc aaacatggta
    17941 ggaatggcca aaaagaaggt gaaatcagcg gccactgttc gactagttcc taaaataata
    18001 gctcctaaga tggtagcccc tgatcgacta gtaccaggca caatacttaa gacttgaaaa
    18061 caaccaatga agaaagctgt tttgtaagac attctagcta attcagtgac agcaggttct
    18121 tgttgagcat ttcgtttttc aatccagata aaggcaatcc cgtagacgat taaagcgatg
    18181 gcaatcggaa ccataaaata aaaatgtgct tcaaaccaat tatcaagagg aaccgctatt
    18241 aaaatagaag gaatacacgc aatcaccact tttagccata attgccaggt aagctgtact
    18301 tctcttgctg ttttcccagg ttgaaaggga ttgagacgtt caaaataaat caacataaca
    18361 gcgataatcg cccctaattg aataacgata ttaaacattt ctataaaagc cttatcctga
    18421 tttagtcgga taaattcctg caccaaaatg aggtgaccag tgcttgaaac tggtaaccat
    18481 tctgtgattc cctcaatgat gccaaagaaa atggctttta gcaattcgat aattaacatg
    18541 ttttctcctt attaaccact cttattgtga ttttctaaac tgtgattaat gccaagcagc
    18601 ttttttaaaa ggcaccgccg ccgccaccac cactaatccc gcctccggaa gagactgaga
    18661 aatttgagga agttgtagct gaagacaagc tagacacaaa ggttggtgtc gtagcataca
    18721 ttaccattga taattcacct ggtcgaacag cttggtaaac ctcaggtaag gcaatacgat
    18781 ggactttcaa atagcgttcc actttcttag tgtaaccaaa taaggtggca taaaccaaaa
    18841 cacggttcca aacaaccaaa ccttcaatag caacatcctc aaatttgtca atgtctcgta
    18901 tcatgttttt aaagctctgc cattgatgta accgaacacc cccctcaggt gtttcaatac
    18961 ccaatttctt gtattgatct aacttcaggc taatgtaaaa gccaaggcac atcgttagca
    19021 ccattaaagc aaggtaaatg agggctaacc cactttcttt aatagccaag taaatcaata
    19081 aaccactatt tagaataagc aacaaacaac ctaatccctg gacactattg ctttttcgtt
    19141 tctctgccgg ggtcatttga cgataagtat ctggtaagtt taactttttg atagtttcta
    19201 ggacattgtt tgtaatagct gccgacgctt ttttcatcgc cttaatcacc tgctcagacg
    19261 attgacggac ttcttgctcg agctttttac ctttgtacgt tttctttaat tgtttaatgg
    19321 tatcagcatc ataatggtat tgactaaaca attgatccac cggcaatgtc accttgtttc
    19381 caaaagccat atctaagaag gcagcttcct catctgtcac acgatctaac tgactgattt
    19441 caagataagc tttcccttct tctttcgtta ataaaagcac cttttggtcg atcagatcca
    19501 acaaggtagc ttgaacaagg gcctcaaagg tcactccttt agggatcaat aatttctggc
    19561 tttctgatgc tgtaggggat aaataggcaa aactctgtcc ataaatcgct tgtgtcaaca
    19621 caagaggcga aagatcttca gggacttcgt aactgtgatc tgtatggtta gccaaatgat
    19681 aacgattgaa ttgtttcttt aatcttgtaa actgtattaa ctgccaaaga agaaaaccta
    19741 cctctaccag aggaatgact ttgccaaata gcagctgtaa caaggtcctt cgtctggaaa
    19801 tcttagtttc taacgctaca attttattct ttttactcgt tgaaacatca actggctctt
    19861 ttcccaataa tgctttttta tcccaataag catgcaattc cagttgccct gagacattct
    19921 tggcattaat ctgatagcga ctgttacctt cttttaacac ttgaggtttc ttttggtaat
    19981 atcctctgtg agcccataga ttagaatcct gaatatcagt tggggtagtg acggtcaaac
    20041 tcaccttttc taatgttttg tcccaatcac taatcggtgt ccaattcagc tctgccacgt
    20101 cttgataagc tgttaaaagg tggtgcagtt gccagataac cttgacgtca accttatcac
    20161 cagcttggcc agcattataa agttttaaac gatagccatc tccaaggtca ctaaactctt
    20221 gactaacagg tacctgttga ccattctgat atacctcaac tttaggcttt tggtcaatag
    20281 caaagcccgc tggcaaatga cctgtccggc ccagcgaaat atactggccg ttataagaag
    20341 tgtcaaattg ataggttact ttttgctcaa accgagcagt attttctttt gataacagta
    20401 actgaccttc atagttggtg atgctatagt ctacatcagc tgcttttatt cgtatcccta
    20461 aaagactgaa gcagagcaca agcgtcatca aaattttttt catggcaaca tcctctttct
    20521 gccctcattt taccatattt taaggagatg acaaaaccta aaccaagtcc ttcatcttat
    20581 ttttaatcat tattttgaat atttttccat atttcaacct attcactgat aatatattga
    20641 aataggatgc aaattgctgt aaaataggtc tgaatactat ttttgaaaca ggagacctat
    20701 atgaaaaagc taatccttag ctgtttggtc gccttggccc ttctgtttgg aggaatgagc
    20761 cgggctcaag caaaccaata tttaagagtc ggaatggaag cagcctatgc tccttttaac
    20821 tggactcaag atgacgcttc aaacggggct gttccaattg aaggaactag ccaatacgcc
    20881 aacggttacg atgtccaagt cgctaaaaaa gtcgctaaag ctatgaacaa agaactttta
    20941 gtcgttaaga cctcttggac cggtttaatt ccagcattaa cttctggaaa aatcgatatg
    21001 atcgctgctg gtatgagtcc taccaaagag cgtagaaacg aaattagctt ctcaaacagc
    21061 tactacacta gccaacctgt tctagtcgta actgccaatg gcaaatatgc tgatgcaaca
    21121 agcctcaagg atttttctgg agctaaagta actgcccagc aaggcgtttg gcatgtcaat
    21181 ctcttaactc aactaaaagg tgctaagtta caaacaccaa tgggagattt ctctcaaatg
    21241 cgacaagccc ttacttcggg tgttatcgat gcctatattt ctgaacgacc tgaagccatg
    21301 actgctgaag ctgctgatag ccgtttgaaa atgatcactc ttaaaaaagg gtttgctgtt
    21361 gctgaatcag atgctgctat cgctgtcgga atgaaaaaaa atgacgatcg tatggcaact
    21421 gtcaaccaag tgcttgaagg attttctcaa acagatcgta tggccctgat ggatgatatg
    21481 gttaccaaac aacccgtgga aaagaaagcc gaagatgcta aagcatcatt tctaggccaa
    21541 atgtgggcta tttttaaagg taactggaag caattcttac gtggaactgg aatgaccctt
    21601 ctgatttcca tggtcggaac cattacaggt ctctttattg gattattaat cggtattttc
    21661 cgtacagctc ctaaagctaa gcataaagta gctgccttgg gacaaaaact ctttggttgg
    21721 ttactcacta tttatatcga aatcttccgt gggacaccta tgattgttca atctatggtt
    21781 atctactacg gaacagcgca agcctttggt atttcgatcg accgtaccct agcggctatt
    21841 tttatcgtat ctatcaatac gggtgcctat atgagtgaaa ttgttcgcgg tggtattttc
    21901 gctgtcgaca aaggtcaatt cgaagcagca actgctcttg gctttactca cggacaaacc
    21961 atgcgtaaaa tcgtgctacc acaagttgtt cgcaacattt taccagcaac aggtaatgag
    22021 tttgtcatca atatcaaaga tacttctgtc ttgaatgtta tctctgttgt ggaactttac
    22081 ttctcaggta ataccgtagc cacacaaacc taccaatatt tccaaacctt tacgattatc
    22141 gccattatct actttgttct taccttcacg gtgacacgta tccttcgtta tattgaacgc
    22201 cgtttcgatg ccgatactta caccactgga gcaaaccaaa tgcagattgc ggaggtctca
    22261 aatgtctaac tcaattattg aaatcaaaaa tctcaaaaaa tcttacggca gcaatgaagt
    22321 actcaaagat atctcccttt ctgttaacaa gggagaagtg atttccatta tcggttcttc
    22381 tggttctgga aaatcaaccc tcctgcgctc gatcaatctt ttggaagagc caagtgccgg
    22441 tcaaatcctc tttcatggtg aagatgtcct tgctgaacac tacaacttga ctcactaccg
    22501 tgaaaaacta ggcatggttt tccaatcctt taacttgttt gaaaacctaa atgtattgga
    22561 aaatgctatc gtcgctcaaa ccaccgtcct caaaagagac cgtgcacaag ccgaacaaat
    22621 cgctaaagaa aacctcaatg cggttggtat gacagaacaa tactggcaag ccaaaccaaa
    22681 acaattatca ggggggcaaa aacaacgggt tgccattgcc agagccttat ctgtcaatcc
    22741 agaagccatg ctctttgatg aaccaacatc agctcttgat cctgaaatgg ttggtgaggt
    22801 ccttaaaacc atgcaagact tggcaaaatc agggttgacc atgattattg ttacccatga
    22861 aatggaattt gctcgtgatg tttctgaccg tatcatcttc atggataagg gattgattac
    22921 tgaagaagga agtcctcaac aaattttcga gaatcctaca caagatcgta ccaaagaatt
    22981 tttacaacgc ttcttaaaat aagataaagg atccaactat ttctatgcca gttgggtctt
    23041 ttttcaattc aaaaagaatt tgtcataaaa tactttacca gttaactatt ttatgctata
    23101 cttatttttg ttaacgttaa taatttatat ttaggaggat aatatggcag aaaaaactga
    23161 cttatcgtca gcttacagaa gactgaaaag tcccaatatt aaaaccagaa aacgtgctct
    23221 gaagattatt cacgagtaca aacgttacgg taaaaaataa gattttactt tttatctctc
    23281 caaatttaag tcagacaaaa aaaggctaag acaccccttc catcttagcc tttttgtata
    23341 cagtttatta agggaactat tttaaaatat cttttatgct agagtctaga atagttcaaa
    23401 acgttaaaat catacattta aggtagtgtt taaagtatac gaaaaagaac tcagcataaa
    23461 ccaagctctc tttcgttata actaattatt tagcaatttt tgcgaagtac tcaagagtac
    23521 gtacaagttg agcagtgtaa gacatttcgt tgtcatacca tgatacaact ttaaccaatt
    23581 gtgatccgtc aacttccatt actttagttt gagttgcgtc aaacaatgaa ccgtatgata
    23641 cgcctacgat atctgaagaa acgattggat cttcagtgta accgaagcta tcgtttgaag
    23701 cagctttcat agcagcgttg atttcgtcaa cagaaacgtt tttgtcaaga gttacaacca
    23761 actcagttac tgatccagtt ggaacaggaa cacgttgtgc agcaccgtca agtttaccgt
    23821 taagttctgg gataacaaga ccgatagctt tagcagcacc agttgagtta ggaacgatat
    23881 ttgcagcacc agcgcgtgca cgacgaaggt caccaccacg gtgtggtccg tcaaggatca
    23941 tttggtcacc agtgtaagcg tggattgtag tcataagacc tttttgaata ccgaatgcat
    24001 cgtgaagagc tttagccata ggagctaaac agtttgtagt acatgaagca cctgagataa
    24061 ctgtttcagt accgtcaaga atgtcgtggt tagtgttgaa aacaactgtt ttaacatcgt
    24121 ttccaccagg agctgtgata acaacttttt tagcaccgtt agcatgtaag tgtttttcag
    24181 ctgcttcttt tttagcaaag aaaccagttg cttcaagaac gatttcaacc ccatcagttg
    24241 cccagtcgat gttttctgga tcacgttcag cagaaacttt gatgaagttt ccgtttactt
    24301 caaatccacc ttctttaact tcaactgttc catcaaaacg accttgagtt gtatcgtatt
    24361 tcaacaagtg tgcaagcata tttggatctg taaggtcatt gatacgagtt acttcaacac
    24421 cttcgatgtt ttgaatacgg cggaatgcaa gacgtccgat acgaccgaaa ccgttaatac
    24481 caactttaac taccattagt gatttcctcc ttatgaaaat caaaagaata ttatttagag
    24541 ggaatgctcc ctacctattg tgaaaagatt aacttacagt catctgtaac aacctttcaa
    24601 cagaactatt atataactat ttcagaaaaa atgcaaataa attagccatt ttcataaagg
    24661 gcagcttctt tcttctagcc ttcaaaaccc accaaatata ggaaagggct ttcttttttc
    24721 tatgttctat tctgtaattt atctttttat tgggaaagat ttccaaaact tcaaactgta
    24781 ctataacgtt ctgttacact aaaaaagagg ttaggatagt tatcctcaac ctcttagtgg
    24841 tggttattca cctttgtttt tcttaatgat ttcttcttga actgacttag gaacatcttc
    24901 atagtggtca aataccatca tgaatgtacc acgtccttga gtagcagaac gaagaactgt
    24961 tgcataaccg aacatttcag caagtggaac ataagcacga acgatttggc tgttaccatg
    25021 tgcttccata ccatcaacgc gtccacgacg agctgtcacg tgtcccataa cgtctccaag
    25081 attgtcttct ggagctgtaa tcgttacaag catcatcggc tcaaggatag ctggttgtgc
    25141 tgatttagct gcttctttaa gagcaagaga tgctgcgatc ttgaaggcag tttcagatga
    25201 gtcgacatcg tggtatgaac catcgtaaag tttagcttta acgtcaacca ttgggtaacc
    25261 agcaagaaca ccgtttgcca tagattcgat caaccctttt tcaacagctg ggataaattc
    25321 acgaggaacc acaccaccaa cgatagcatt ttcgaattcg aaacctttac cttcttcatt
    25381 tggtgtaaat tcaatccaaa catcaccgaa ttgaccttta ccaccagatt ggcgtttgaa
    25441 gaatccacga gcttgtgtag aagcacggaa tgtttcacgg taagatactt gaggagcacc
    25501 aacgttagct tcaactttga actcacgttt catacggtca acaaggacat caaggtgaag
    25561 ttcacccata ccagcgataa ctgtttcacc agtttcaacg tttgtttcaa cacggaatgt
    25621 tggatcttct tcagcaagtt tttgaagggc aacacccatc ttgtcttggt ctgctttaga
    25681 ttttggctca accatcaact ggataactgg ttctggaact tcgattgact caagaataac
    25741 ttttgctttt tcatcagtca atgagtcacc agttgttgtg tctttcaaac caacagcggc
    25801 agcgatgtca ccagcgtaaa ctgtttcaat ttcttgacgg ctgtttgcgt gcatttgaag
    25861 gatacgtccg atacgctcac gtttaccttt tgatgtgttc ataacgtaag aaccgctatt
    25921 aagaacacct gagtaaacac ggaagaatgt caaacgacct acgaatgggt cagtcatgat
    25981 cttgaaggca agagctgcaa atggctcttc atcagatgct ggacgttctt cttcagcatc
    26041 tgtatccggg ttaacacctt tgattgcagg gatgtcaagt gggcttggaa ggtatgcgat
    26101 aaccgcatca agcatcaatt gaacaccttt gtttttgaag gcagaaccac aaagtactgg
    26161 gaagaattca acgttgattg ttgctttacg gataccagca atcaattcgt cgttagtgat
    26221 ttcttcacct tcaaggtatt tcatcatcaa gtcttcatca gtttcagcaa ctgcttcgat
    26281 taatttttca cggtattctt gagcttgttc taagtattct tctggaatat cttcttcaag
    26341 aatatctgta ccaaggtcgt tggtatagat ttctgctttc atcttgatca agtcaatgat
    26401 accacggaaa tcatcttctg caccgattgg caattggatt gggtgtgcat ttgcttgaag
    26461 acggtcatga agggtttgta ctgagtaaag gaagtcagca ccgattttat ccattttgtt
    26521 ggcgaaaacg atacgtggaa caccgtattc agttgcttga cgccaaactg tttcagtttg
    26581 aggctcaaca cccgattgtg agtcaagaac ggttacagca ccatcaagaa cacggagaga
    26641 acgttgtact tcgatggtga agtccacgtg tcctggtgtg tcgatgatgt taacgcggtg
    26701 accatcccat tgagctgttg tagcggcaga agtaatagtg ataccacgtt cttgctcttg
    26761 ctccatccag tccatttgtg atgcgccttc gtgcgtttca ccgattttat gaattttacc
    26821 agtgtagtaa aggatacgct ctgttgtagt tgttttacca gcatcgacgt gagccatgat
    26881 accgatatta cgagtttttg caagtgaaaa ttcgcgagcc atgtgtttct cctatttttt
    26941 tagtttactc tttcattata gcactattta gcaaaaacgg ataggcagga cctacccgtt
    27001 atctaaatat ttgttggtaa agataatacc tattgccttt ataaggcttg gtatcttatt
    27061 cattgaactc aggctaaacg ctgtgtgaaa aagataaact ttcctagaga caaaggtttc
    27121 ttcgtcaaat ttcctatttt cactttgcgt tctatacgcc ttcgtatctt attaattgag
    27181 ttcgagctac aagccactga caaaaagata atagttccta gaaactgaag tttctgcgtc
    27241 aatttcccta ttttgtctag catttgtttg acgctaaaat atcttatatt accaacggaa
    27301 gtgagcaaag gcacggttag cttcagccat tttgtgagtg tcttcacgtt tcttaactga
    27361 tgcacctgtg ttgtttgcag catccatgat ttctttagca agacgatctt tcatagtgtg
    27421 ttcaccacga gcacgtgatg cgtttaccaa ccaacgaagt ccaagtgttg tacgacgttc
    27481 tggacgaact tcaactggga cttggtagtt agaaccaccg acacggcgtg cgcgtacttc
    27541 aagtacaggc atgatgttgt ccatagctgt ttcaaatact tcaagagcgt catttcctgt
    27601 tgcttctttg atagcgttga aagcatcgta aacgatagta gcagctgtac cacgtttacc
    27661 gtcaagcata acacggttga taagacgtgt tacgattttt gagttatata atggatctgg
    27721 taatacttcg cgtttaggcg cttgattttt acgactcatt ttctcttatc ccccttctat
    27781 tatccttttg gacgtttcgc accgtattta gaacggcctt gtttacggtc agcaacacct
    27841 gcagtatcaa gtgcgccacg aacgatatgg taacgtaccc ctggaaggtc ttttacacgt
    27901 ccgccacgga taagaacaac gctgtgctct tgcaagttgt gtccgatacc tgggatgtag
    27961 gcagttactt cgataaggtt gctcaaacgt acacgagcga atttacgaag ggctgagtta
    28021 ggttttttag gtgtcattgt tccaacacga gtagcaacgc cacgtttttg tggggcagcc
    28081 attttagttt gaactttttt gtgactgttg taaccaatgt tcaaagctgg tgaatctgat
    28141 ttttcaattt tagatttacg tggtttacgt accaactggt taattgtagg catctacatt
    28201 ctcctgtgtt tttttatttt tggttgatat agcacttggt gacagcccat atccggtgca
    28261 ctttttgcaa caattgtcag cacgtctctg tacacttttg agagaccaaa agtaaaaagt
    28321 accgtctaat ataataacac agacggcact tcatgtcaaa tagaattttt cctttgatgc
    28381 aattgcttat gacgaatgca tcacttagat tccttacgga acctaaatcc tgtgaggccg
    28441 acagctgcca acatgacgac tcctgcttta agagctcttt gagtactttc atcaacatca
    28501 gaaatgagat tgctcgttgt agaagatcct gagccataag atgtcttaga tgagggctga
    28561 gtaatcgaag atgtgatttt agacacaatg gcattacttg ctaccatttc agaggtttgg
    28621 ccaacaagcg cttctgctac aagacttgta ttttcagcag ctaatcttgc tgaagcttct
    28681 aatagttgtt tcgtttcttt aaccatttct tgaacaagcg gagtagtatc tatcttacta
    28741 tatgatagcg gttttacgcc cgtaagaggt ggagctactt gcaaatcagg cacagtagct
    28801 atatcttcgt ctaagtggcg atattccttt tcgttagcta aggttttaag caaagtcaac
    28861 tggtgttctg tggtagcaat agtagcttct agactgcttt gtttagcttg taaggctgct
    28921 aaagcttctt gtgcatttaa caaagatgag gtagttttag ccaaatcttg cttagtatta
    28981 tcaatgcgct cacgtatcac ttgaaggcgg ttaggattca atttaaagtc ccttagatat
    29041 tgcaaatgag cttttttagc caccagtgct gtcactctgg ctgcggcttg ctctgctaag
    29101 gcttctgtct ggtgcagtgc ggctttcaac gatgctagct tagctaatga ttgatcacga
    29161 gtagcttcga gttgtgcttg ttttgcttta gctgctagta attctgttct caaagaacct
    29221 ttagtatcat ttaattgtct cacttggaga tttaagctgt ctgactgctt aagtgtgctt
    29281 gctaatttac cttgaagttg acttacttta gcttgggctg ccataatatc agcttcttga
    29341 tgaatagccg acaaacgatt ttctaatgag cttacttttc ctttgatcgc tgcaatagta
    29401 tcagatacag tgcctactct ttgggcataa tcttttgtac ttccaacggc ttttataggg
    29461 gtcttattaa agcgttgatg gttagcaatg ttagactctg gaaacattac aaagtgttca
    29521 ttcaaagatc ctacattgct ggttgaaaat ccaaggtaaa caggcgcatt agggttatgt
    29581 ttatctacac gtaaaaagtt aatagcatgg ccgtatgtat ttccgtgtaa atgatctgta
    29641 aagagcatat acttgatact gtcataaata ccacgtttaa taccattcac agtatgcaca
    29701 tcgttaaaag caccgatatt ctcgtacatg ttatcatcat ttcgaatgag ccctgacgct
    29761 ccggcagagt cttcaataat agttttatca tgaggcccaa caccataatg ccctgatacc
    29821 cctggctgtc cgtagacaaa tgatggtctt gtattaccat gagttttctt atagctggta
    29881 ctaagtaatc ttgcaaattc ttgtgatcct gctgtaacag taactggtgg tagacctaat
    29941 tgtcttctta cactattaat catgtgagct gcaaactgcg ctagctcatt ttgcacttct
    30001 ggtgtcaaat tatcgggatc aacaaagcga ttacgatctg ctggaatatc ttggtattga
    30061 tttaattgat tacctggact agctttggca ataatttgat ctgcatgctc tttgtaataa
    30121 ttattgtaac tagctgatcc aatataacca ctagcttcta attttttaag ttcttcaaga
    30181 ggatagcctt gcggtgcttt catggtatta ttacccacaa tgctatcttg agtagacgga
    30241 gctgaggatt taagacgact aagttctgcc tctttttctg ctagagcagc tttctgagct
    30301 gccaactctt cagtcaattg ctttttaact ttagcttttt gattttctaa gtcagcttta
    30361 gccttctcca attctgagct taatgctttt gtattatcat tagccgtttg agctgcttta
    30421 gtgatagcat caggattgct aatcatagca ttgagcttag caatattttg ttcagacgtt
    30481 ttgacttgtt ccactaaatc ttgagctcga gtagtttctg ctgaaatgct agctttttgt
    30541 tctgacaatg cagtctcttt tgaatgttga tctgcttgag cattatgaag ctctgtttca
    30601 gtagctgtta actctctttg atgttcggct ccttgggcta atagcgtctc ctcactactt
    30661 gcaagagtat tagtgtaaat ttcttgtgca gaggttaaag ctttttgttc attatcttgc
    30721 tgctctttta agtggttgat ttcagcagta gtttttgtca gagcggtagc aagctctgtc
    30781 agttctgctt tttgttgact gagagttttt tcaactgcat caatagttgc ctttgcctct
    30841 tgaattgttt ctggttttgg taaactatcg tcgtgagtat tactcgcctt cgtttctcct
    30901 gaggctctat catctgcttt gacttggtga gatacgccta cactggcact caataaagca
    30961 attgttgagg ttaaagcaat tttctgctta acttggtttg gcttcgtttg ttctaagtcc
    31021 attctctctc ctttttccat ttatcgaaaa tattaccaac ttctacaaca acattgttgt
    31081 ttttgacatc aatctctgaa actttcagca atgatttgaa ggtcatttgc tcacgctctg
    31141 attgagcgtt ttctgcaaac acagcaacac caactaaagt gctgtcaaat tctgtcaaga
    31201 gactgatcat tcctgtaatc gtccccccgc ccttcaagaa atcatctaca atcaatacac
    31261 gactattggg tttcaaacta cgctttgaca gaaacatctt ttcaatacga tcactagaag
    31321 cactcgcata attgacagac actgtcgatc cttctgttat ttttaaatca cgtctaacaa
    31381 tgacaaaagg aacacttaaa atattagcca ctgcatttgc taaaggaact cctttggttg
    31441 caactgtcat cacagcgtca atcttttctc ctttaaaggc attggcaata atacgaccaa
    31501 tattttgtaa aattttaggt gtactcagca agtctgacaa atagatatag cctccaggta
    31561 agatgcgatc actctctgat aacctttgac acaggtcttc aacaatggta cgcgcttctg
    31621 tttctgaaat actgggggta aaaattacgc ctccacttgc tcctgtaagt gtatcgatat
    31681 caccaatgtt agcttcttca aaagctttct tgataatagc gatatcttct gagatagaag
    31741 attttgcggc ctcatattta gttgcaaagg tgtttaaact agttaattta tacggattgt
    31801 taatcaaata atttgaaatg acaaccatac gttcacttcg tcttaatttc atagtttccc
    31861 catttttatg tactttttgc tattatacca taaagttaat aaaaaacgaa cattcgatta
    31921 ggaaaatatt ggtttttttg ttcttattaa tatcatgcaa gaattcaatc taagataaac
    31981 taatcaacat tcctactgaa aggacattct acttaataac cataacaaga gccaaaaaca
    32041 cttatgaaac catcataagt gttaagcaca tcaaaaatca tcacaaaagc aaaggaacta
    32101 ttactcgaga aacactgatc aatagtttgg cttgtaaaaa gaccgattat ccatggcaaa
    32161 aatccgattg gtcatctcgc cctcgctaac acggctaaga gctgttgtca tcatcatcat
    32221 attagcatca atattgtcaa tcatatgaat aatttcagct tccatgatgc gtggacgtac
    32281 cggactaccg tattctaatt gcccgtgatg gcttaaaatc acgtgcctaa ggacaatgac
    32341 ttcttctttg gtatcatcga tttgtagttc tgaaattact tttgtaattt cttcgttaat
    32401 gagagaaata tgcccaatca agttaccacg aacggtgtat tctgtattat ctggtcctgt
    32461 taattctatg actttagcta agtcatgtaa cataatacct gcaaacagta gactcttatt
    32521 taagtcaggg tagatatctc caatgctatc tgctagtctg accatcgtag cagtatggta
    32581 ggcgaggcct gactcaaaag catggtggtt tgttttagct gcaggataag tataaaattc
    32641 tttatcatac ttacgataaa gagcccttac aattcgttgc cacgttgcat tttcaatttt
    32701 aaagagcatc tgttccaaat agtcacgtac ttctgtcaca ctgacaggtg ccttttcttt
    32761 gaagtccttt ggatcattgg gctcacctgg gcgaacattt cgcaaggtga tttgattaac
    32821 ctgaggggta ccattataca cctcgcgtcg ccctttcata aacacgactt taccagcagt
    32881 aaattcttca acgttataag gttgggcatc ccacagattt cctgaaatct cgccagtgtc
    32941 atcctgaaag gtaaggctaa taaaatcttt accagctctt gtcttacgaa cctctgccga
    33001 cttaatgagg tagaaccctt caaaaagctg gtcttttttc atttgattaa ttttcattat
    33061 tttcctcttc taataagggc atgttcaaga gagattttgt tgcttggtct tgataagttt
    33121 caacggtatt caaggctcga acaatggcat ttgtccttgt tgaaatgagc tgatccagcg
    33181 tattattagc tgtattcatt tgtttttgag ccttggcaag caggccgcca aatttatcga
    33241 attctaactt gacattgcct aaaattttac tgatgtcatc agcatttttt tggatattaa
    33301 gggtcttgaa accaacagat aaggaattca gcaaagcaga cagggtcgaa gggcctgcaa
    33361 ccacaatatt ttcttcccga cgaaggctat caaagaaaga cgcatttctg accacttctg
    33421 aataaagacc ttctgttggt aagaacataa ctccgaaatt ggtcgtctct ggggggttca
    33481 agtacttttt atgaatgtct ttggcaaagc gtttgatagc tgccagaagt gcttttcggc
    33541 tagcctcgat ggccagttta tcaccaactt cgtaagcatc ttctaatcgg taataatctt
    33601 caagagggaa ttttgagtca atcggtaggt aaatataacc gccttgacca tttcctggga
    33661 gcttaatcgc atattctacg cgttcactag aaccactaac cgttacaaat tctctttcgt
    33721 actggcttga tgtcatgata tcctcaatga tttggcctag ttgaagttcg cctaaaatgc
    33781 ctcgtgtttt ggtattggac aaaaccttat ttaaagtacc cacatcttga gccacgctac
    33841 gcatttctcc caagccttta ttgacacttt ctagttgctt ggatacagaa tcgaaagagg
    33901 cgtgcagacg attttttaag gtttcttcca atttttcttc aacgatctgg cgcattttct
    33961 ccaaacgttt ttcgttagat tcttgcatat ttttgagcga ttggttgacc tgctggttaa
    34021 ttttttctaa gcgtttgtca gaccggtccc tactatcaga caaactacgg tgcaagacgt
    34081 cacgaatatc tgttaattgt tggtaaaggc ctgcttgttg tcggttcatc agctgtgtta
    34141 gctctaacaa ttgttgcttg ttagctgtat ccaactggta ggtcatttgg tcagacaaat
    34201 tatccgcgtt gccttctagg gtttgggcaa gctgatgttg aaggccgttg actttgaaca
    34261 acagataagc ccctaaacct aagagaacca agaccaaaag gaacaagata aggtccatac
    34321 taactccaat ctttactttg aataataatc aagtagccac ttggcaaact aactgtaata
    34381 ggttgatgga taaaggcatt actggaatag attttctttt tgaaaaaatt atcttgcgtc
    34441 aactcaaatt tagcaccagt aatggtcaag tcagcttctc cttctgccat aaatgccaca
    34501 taggtcatcc cttcttcttg atggataagg tgctgacctg ccgggcggta ggtaatcata
    34561 ttttgttggt cacgcaaggc gatttgtgcc ataaagggag caataccagg gtcgctaggc
    34621 aagaaaatat tggataagag gtggtccatt cgacccccaa aagccccaaa aatggtcact
    34681 tccgcctcag gaaaacgagc aaagacctct ttaagggcta attccgtatc cgtatcattt
    34741 ttttctggat gagcagtaat aaaaagctct gccttctctt ttatatccgt aaacgctttt
    34801 tgggaaaccg aatcaaaatc accaacagcc atattcaaag gaagcccatt ttctaataaa
    34861 aataggctcc ctctatcaat accgacaaaa taatcaaaat cacggctgat ataagagaga
    34921 tctcctcccg caaaaagagc aactttagac attcaaggcc gtccttaagg tttggacttg
    34981 gctcactagg tcactggcct tgaaaaggta agaacctgcc acaaagacat tggcccctgc
    35041 ttcataacaa gcacgaatgg tcttattgtc tactccgcca tcaacctcaa tgtcaaagga
    35101 caatcctttt tcatctcgcc atttggctac ggtagccact ttttctaaac attctgggat
    35161 aaaggcctga cccccaaaac ctgggttgac tgtcataatg aggacttggt caactaagtc
    35221 tagcaaaggt tctagggctg ttgcaggagt tcctggatta atcactaccc ctgctttcat
    35281 gccagctgcc ttgatttttt gaagggctcc atgaatatga cgagtacttt ctgtgtgaat
    35341 ggtcatgata tcagcaccag cttgtgcaaa agcctcaaca tagcgttcag gatcaaccac
    35401 cattagatgg caatcaaaga ccaatttact gtgctttctc atacttgcca caacatctgc
    35461 accaaaactg atgttaggaa caaattgacc atccataata tcaatgtgaa cgtattcggc
    35521 atctgtttct tcaatacgag ctagctcaga agcaaaatta gcataatcag ctgctagaat
    35581 agatggggca atttttagag ttgacatgga gtagacctac tttcttttga taactttttt
    35641 atatgtttca cgacggtttt caatttcact gagaaattgc aggtaatgct cataacgaac
    35701 tggccacaac tctcccgttt caagcgctgc cttgacagca cacttgggtt cgtgggtatg
    35761 ggtacaggat ctaaacttac actcatggct cagccggcgc agctctggaa aagcctcgtt
    35821 caaatcttca gcattagcaa tatcatagtc taatgatgaa aaacctggcg tatccgcgat
    35881 ttttccgcca tgggtattgt aaaaactcac agctcgggtg gtgtgacgac cacgccctag
    35941 actatctgag atttctccta tttcaagagc caattcgggg gcgattcggt tgagaagggt
    36001 tgatttccca acacctgttt gtcccataaa gacggtaatt ttatcagcta gcaaaggcag
    36061 caattcctca agactggtca caaaatcgta accgattgcc tgatactgtc gaccaatagc
    36121 cttaatctcc tcgggactat ctaataagtc catcttagag atataaacca ctggatgaat
    36181 ggctttgtgt tcaagcaaga tgagaaagcg gtctagaaga ttgctgttaa attctggttc
    36241 tttagcagac ataataacca ctgcttgatc aatattgacg ataggaggtc ttaccaaact
    36301 gtttttacga ggatgaatcg ctaaaatata accttcagag ttgtcctctg ctgagaaatc
    36361 cacgatatct ccaacataag gtgtctcacc gcgcttccta aaattaccac gcgctcgcgt
    36421 ctgatatacc tgtccttctg actccacgta ataaaaacca gccagagatt taatgatttt
    36481 accttgcaac tgtgctcctt tgccctacta taataactct attatatcag aaaaccgctc
    36541 ccaaatcagc atttgagtct aagtttcact cgctttaaaa actgtcaaga ttctctagac
    36601 cactggctat catttaggtc actgcttttt aaaaatagaa tattttatca actaaaaatc
    36661 agatcactga tgattttttg aggtaggaaa cgatatgaat tttaagaaga cctttgctat
    36721 ttacgaaaaa gagtctaacc gtaccgctat agtcacgctc ttgttaattg cccttttttt
    36781 ccggggtatt aaaaaaacta gctctgcact gcgatgcctt aacggccagc ttcaataaga
    36841 aaaatccccc tgaactgaac atctctgttt tgtctacaag ggaatttttt tattgtcacc
    36901 gggggaaagc ttttataatc caacttcttt taaagcatca gctaatttgc caaaatcttg
    36961 aatcgacaag gcctcaccac gaatagaagg cttgatatct gctagtgcca gacctttttc
    37021 aagtttagcc ttgatgtctt cagacttccc aaaatggcta gtcaagttat tccacagggt
    37081 cttgcgacga tggacaaaac tgagacgaga cactctgaaa aagaaatctt cgtccttaac
    37141 ctcaatcaaa ggctggtcgc gacgcaccat tttgaggata gcactatcga catttggtgc
    37201 aggtacaaag acggtgcgcg gcacaatgaa ggcaaccttg gcagtcatgt aatactgcac
    37261 cgcaatggac aaggaaccat aagctttagt gtttggctcc gcagaaatac gatctgccac
    37321 ttcacgctgc atcatgacca caaactcttg gaatggaatt ttgctctcaa tcaagtgcat
    37381 gagaataggc gttgtgatgt agtaaggtag attagccacc accttaatgg gcaaatcagg
    37441 atttttaaac tgcttgattt gggtctgcaa atcagctttt aaaatatctt gattgaccac
    37501 ttgcacatta tcaaaatcgc gcaaggtatc tgccaaaatc ggcaccaagc ggtcatcaat
    37561 ctcaaaaacc atcacttcag cagcattttc tgccaaaaat tccgtcaaag ccccaattcc
    37621 aggaccaatc tcgataacat tgacattctg atcaatctca gccgtgtcaa cgattttctg
    37681 taaaatattg gtatcggtca aaaagttctg accaaaagat ttcttaaagg taaatccgtg
    37741 acgatcaagg acagccttgg tcacgctata atctgcaatt ctcatatatt ctcttctttt
    37801 tatgatcact ttctttttgg catttgaacc actagcctaa acttttttgc caggacacgc
    37861 cattcagtta atggggctgt tatattttat tgtactcttt actcctcata tgtctccatc
    37921 acttcttcca cttctgctag ggtaatgcca aataattcga ggcgcttgag cagttgtttg
    37981 ccgttggcat aaccgatgcg gagcttttca cccaagtatt ccctgcgttt acggctatct
    38041 gacgccatta aaagccctag acgaatcagg tctgtttgac gaatgtcaaa ataagactca
    38101 tcatcatatt gctgagtgac atgagcaagt gccttttgga gatcctcaaa attggcatgt
    38161 tcaaccccta aggaacgacc cttactctta gaactcggaa ccgcctcgtt tcggtttaaa
    38221 aaggcatgac gagctgttgg cacagcagcc ataatgagct tacgaatgcg ctcaccatta
    38281 taatctgggt ctgttaaaac gataacacca cgcaaatcgt ttaggcgatt gattcgttct
    38341 aaatcttctt cagtgatagc agagcctcta gtctcatagg tatccacctc gtaaaaacgg
    38401 cgtaggttag ccgtgtcgtc cttgccttct acaacaagaa cctcttgaat attaattttt
    38461 tcagtcaagc ttgaataccc tctttgcatt agcagtcgtt gcttttgcaa cttcttccac
    38521 agtcatcccc cgtagctctg cgattttatc aaccacatag cgggtataag ctgtatgatt
    38581 ttgtttgcca cgttttggaa ctggtgtaag ataaggggca tctgtttcca ccaaaatctt
    38641 atccaaaggc aagtgctgcg ctgcctcttg aatatcaaga gcctttttga aagtgaccac
    38701 acctgaaaag gaaatcatca tgccaagttc aatgaaacgt tcagccatct ctaatgaccc
    38761 tgagtaagaa tgcatgatgc ctccacgagg gccaacacca gctgctttga tgacctcata
    38821 ggtatcttcc aaggcatcgc gggtgtgcac cacaaaaggc aaatcatggt cttttgctaa
    38881 ttgcatttgg cgcttaaaaa cctctatttg cacctctttg gggtcctcca tccaataata
    38941 gtctaagcca atttcaccta aggcaatcac tttggaatgt gataattgag agacgatagc
    39001 ctcctcaaca gcctctgaat aagaacctgc ttctgttgga tgccacccaa tagttgcata
    39061 aatattggca tatttattgg ctagagttag tgccccacta atagtggcct ggtcaaagcc
    39121 aaccacatta tggtaggcca cgcccatttc ttgagccaaa gtcaattctt cagtttcgtg
    39181 tccttgaaat tctgctacat tcaggtgcgt atgggtatca aaaatagtta gtttttctac
    39241 tttatttgtc atgatgttat tataacataa agatcttaac cacatcagaa aacttggtga
    39301 gaacttctgc cgtttaggtt gatcgtaaaa ccctttgcta gctgacactt gtctattttc
    39361 tacttttttg acaaatgacc tttaatagtc ggctcctaca taagccctca aaaatactac
    39421 aacctactca aataaagtgg gttgaacaaa tctgtatcac aaaaagggtc gctaccttct
    39481 gttagcgatc tatgctatac tagtaggtag ttaaactgta aggagtgtgc tttgctatgc
    39541 ctaaaaacca ccgcctaatt accaaaatcg aagcatcatt ggaacatatg accagtttag
    39601 aaaaagggat tgctcatttt tttattacaa ccgatctgac acctcaagag ttgaccgcat
    39661 ccgagatagt taagcgacta cacatctctc aagccgcctt gactcgattt gcaaaaaaat
    39721 gtggttttac tggttatcgt gcttttgcct ttgattacct tcacagtctt caagaatcac
    39781 aagagacttt ccaatctatt cacttagaat tgacaaagcg cgtgctgatg gactacgacg
    39841 ctcttattaa taaaacctat gagctcgtta atgaggaaaa attactgaac ttagccaagc
    39901 tgatcgattc ttctgagcga gtctatttct ttggcaaagg atcttctgga ctagtagcaa
    39961 gagaaatgaa gctacgcttt atgcgacttg gtttaatctg tgatgcttat tcagacactg
    40021 atggttttac ttgggcaaat agcctcgtca atgaaaattg ccttgttttt ggtttttctt
    40081 tatctggcaa aacaaactct gtcatcacag cacttcatca agctagtcag cgaggagcca
    40141 aaactgtcct cttaacaaca gataatcaaa ccgaatttga cgactcctta gatattattc
    40201 ccgtatcatc aactcaccaa ctacattatg ggaatcgtgt gtcaccacaa tttcctcttc
    40261 ttattatgat ggacattatt tatgcttacg ttttagcgat tgacaaaccg cacaaagaaa
    40321 aaatcttcaa aaacactatt attgacaaag aaaataacga cctttagact acaatagcaa
    40381 aaagggcgtt gttttctttt taaagggtcg tcattcacct cccccagtat acttaaacaa
    40441 gaactcttca cgtcatatag actcacagcc actaagatta gctactcgct aaattatttt
    40501 cgattttctc aagagttata aatgaacaag atcgctcatt cttttgttta aaatggtagt
    40561 aagctcctaa tataccagca ttatttccat gactagcaaa cttcagctga gttttcttgg
    40621 caagactaga aaccaagtag ctatcaagag ctgtctttaa tttatcagct aaatagtctt
    40681 tttgcgccat gataccgcca ccaagcacca ccacatttgg gttaacaacg tagcagatat
    40741 tagcaatacc ttgtcctaag taatccacct gcttactaat ggctgctata caaatcgcat
    40801 cacccgcttt agcctgctca aaaatacgac gaccatccca ttggctaatg tcatcgccat
    40861 aagctaagac cacctcttga acaagagctg tggtagatgc cagatcctga aactgaccat
    40921 ctgacaaatg aaggtaacca acttcgcaag ctgaatgact actaccatga aaaacttggg
    40981 aattaaacaa taaacagcca ccgattcccg tcccaattgt caagcaaaga gccacaggat
    41041 aatccttggc actaccagaa atagcttcgg ccagaccagc acagttaaca tcgttttcca
    41101 cttcacacgg taacccgaaa gtctcttcaa tctctttttt aaactgagtt ccagcatagt
    41161 taggaatctg agggccggca taaaagattt ctccctcatc aggattaacc attcctgcag
    41221 aagaaatggc cactccagcc agatccattt ggtcttgata ggtctttacc aagcccttga
    41281 ccttttccaa aatagaggga ccacctttat aagcctcagt ggccatttcc tctttttcca
    41341 acaggtctcc tgtttcagaa atcaagccat acttgatagc agtaccacca atatcaattg
    41401 ctaaataatg cttcatttgt tatcccctcg catcttatca aaaggtttcc ttagcctgat
    41461 taatcagagc agcagcccgt tggcaaataa ccctatcttc ctcgaccaac tcagctaaag
    41521 gtgatcgaac agaaccaata tcaagaccct cattaatacg aagtacttct ttaataaccc
    41581 catacatatt gccgtgagca gaaacaagga caccgataat ctcattaata gtatattgaa
    41641 gggccttggc cttttctaaa tccttgtcag caataagttg gttcagcctt aaaaataatt
    41701 ctggcatagc cccgtaggta ccaccaatgc ctgcagcagc acccatcaag cgccctccta
    41761 gaaattgttc atctgggcca ttaaaaacaa tatgatcgtc cccaccaatc gcacagaagg
    41821 tttgaatatc ctgcactggc atagatgaat ttttaacgcc aatcacgcgc ttattagcca
    41881 acatagtctt ataaaggctt ggcgtcaagg caacccctgc cagttgagga atattataga
    41941 tgataaaatc tgtgtgagga gcagccgaag aaatagcatt ccaataatca gcaaccgcat
    42001 attctggtaa ccggaaataa ataggcggaa tagctgcaat ggcatccacg cccaaacgtt
    42061 ctgaatgagc tgccaattca atactatctt tagtgttgtt gcaggcaacg tgattaataa
    42121 tcgtcagctt gcccttagcg actgccatga cattttctaa caccaattga cggtcaaaaa
    42181 cgctctggta aatacactct ccagaagagc cattaatgta aagcccctga acccctttgt
    42241 caatatagta ctgggtcaag gcacgcacac gctcagggct gatattcccc tggtcatcgt
    42301 aacaagcgta aaaggcagga ataatgcctt ggtatttcgt aagatctgtc atagtaatgt
    42361 cctttattca atgtcattat taagtgggaa tcgcctaaga agagattcca tgataatcaa
    42421 gtagagataa gttagactac tgatgccgat gatagctagc aaagacacgc ctccaaataa
    42481 cgttaacaga gacaattgta ggctaaatat cgtgagacaa ataaaagcca agaaagcaaa
    42541 actccatgga aaaaagagtc ctgctaataa aaagcttcgc ttaaacagcg tagataggga
    42601 aaggtctctt ttgacggcct gaggataagc gtacaaaaag agtataacca ccaaaaataa
    42661 aacagcaacg caaagtactt taaacccttg aaaaactagg cctgattggt ttcgaattaa
    42721 gaaaagatct aagagacaaa tagtcattat cccaagctca ataaggccaa ggcgtagccc
    42781 acttttaaag taatatttaa aatgagagct ataagtagta acaagctgac taacttgacc
    42841 ttctcgccaa tccaacaaac tcgcatacaa agccatttta gcaaccccaa tcgttagaag
    42901 gggaaggcag gacaagacaa ataagagatt aaacacgagc aaatcaaaca gtgctgcgct
    42961 agccctcatc catttactat caagcttgaa gagagagtgt aaaagtccct gttttttcga
    43021 tgtcaaatca caacttcctt tctagaaata cgcttacaaa caaaagctaa ctctcctctt
    43081 aaacgtttaa cacatgactt gcttcccatc tgatttatct atgtatgcac ctaaattaat
    43141 aagcaaccta tagattaagc ttagcgacac gctttattta gtctaacctt tcacagcacc
    43201 catagtaatg ccttgggtaa atgatttttg gaagacaaga aagactgtta caataggcac
    43261 tgcagccatg gcagcccctg ccataatcaa gccataatta gtagccattt cagcttgcat
    43321 agtggcaacc ccaagtgaaa tcgttaaatt ttctcgagag gttaacatca ctaactgcat
    43381 aaaataatca ttccaagtat tgataaaggt aaaaatcgct agcgctgcaa agcctggttt
    43441 gacaataggg aaagccacat tgaaaaaggt acgaatttcg ccacatccat caatcttggc
    43501 ggattccaat aactcggttg gaatattttc tgagaactgt ttcataagga aaacaccaaa
    43561 tggccagccc acaagaggca aaataacagc cgccaaagtg tcatggattc ccataaaatt
    43621 aacaatccgc acaagaggca ctagaacaac ctgttttggc aaggccatag cagcaataaa
    43681 aatcgaaaac aaaagccgct gtccataaaa ccgctttttg gccaaagcat agccagccaa
    43741 cgaggaggtt ccacaaacca agaacatggt cgccaccgaa ataaagacac tattccacaa
    43801 ccattttaag gctggatttt gcactaccaa ggccttaaaa ttttcaatag taggcgcctt
    43861 tggccaccat tgcggtggaa tcataatggt atcggcttga gccttaaatg ctcctgtcat
    43921 aatccaataa aatggaaaaa taaacaaaat ggtcaaaaca catagcatca cagtggttaa
    43981 gatatctgat gcggttagtt tctttttcgt catcttaata tcctcctaat attccacatc
    44041 attacctaaa attttaaatt gagcaaagct gatgattgca atcatgactg ccaagaatac
    44101 acccattgtg ttggcatagc cgtattcaga gagcttaaag gccttttcat acaaatagta
    44161 catgagggta ctggttgaat aatttggccc tccagacgtc aaaagttgaa tcaaagcaaa
    44221 acattggaag gaattaatgg ttgttatgac agcaatatat aaggttgttg gcagcagact
    44281 tggccacttg atattccaaa acacctgaaa ttctgtggcg ccgtccacac gcgcagcttc
    44341 taccaaagag ttatcaatat ttcccatagc agcaatatat agaataatag gctgcccaac
    44401 agatgtggtt aataaaataa caataatagc caacaaagcc cagtgcttat ctcccagcca
    44461 actaatattt tgttcaatca catgagcata ttttaagaca taattcaaaa tccctgacat
    44521 tggatcatag atccatttcc aaaccaccgt caccgcaaca cttccggtaa caacaggcag
    44581 aaagaaaact gcccggtaaa acgaacgcgc cactacattt ttgtcgtagg ttttagccgc
    44641 cacaaagagg gaaaagaaaa ctacaacagg taccgaacca ataacaataa tcaaggtgtt
    44701 aataagagac ttcatgaaaa tgggatcttg aaacatccta gcataattag caaaaccaac
    44761 aaaggtaaac tctgtcatgg aataattgaa aaagctcgtc acaaagccca taatcatcgg
    44821 tatcaagaca aaaatcacaa agaaaaccaa gaccggagct aagaaagcgt atgagatgag
    44881 cgtctctctc atttttaatt tattgacgtt cacttgaaat acctcttttt tctgttcaac
    44941 ttttctaaaa agaaaagctt ctttccagtg accatttgac atgtgcattg aaaagaagcc
    45001 acttgttagg aacacttatt gtgttttttt gattgtcttg tttgcttttt cagtgaaggc
    45061 tttcaaagca tcttctggct tttcatcacc attagagacg gcttgaacca ttgggaacca
    45121 aagagttctc atttcagcaa acccatcaat cgtgttatag tatggtgagt agaattttgt
    45181 ccattcagca attttttcca ttcgtttgtc tttgtaaaga tccccataag aagttcttac
    45241 agggaaagca cctgtacgaa caacattttt aggtccccat tctttatcat cagcgataaa
    45301 ttggataaat gtcttagagg cagcgacttt ttgttcatct ttgttattaa agaccgcaaa
    45361 accatttacg aggtattcta gttctggttt gccatcatct gatgggaatg ggatttcaag
    45421 gtaatccact ttactagctt ctaacaattt agcttggatg cctggttgtg caggcgccca
    45481 aagaatggta aaggaagttt ggccattcgc aaagttttga atatcagctg aaccatcgta
    45541 ctgagagcca ttcatcatta aaccatcttt aatccaattg gaaatcttgg tcatggcttt
    45601 aatagagtta gcatcatctg tggtgtattt ggttactttg tcatcggtaa tatgactact
    45661 ataaaggtta gcaaagaagg cacgtggtcc ttggtcacca ccttgaccat tagcaaagaa
    45721 agaacctggg ttatatcctt tgtccttcaa tgctttcaag actttttcaa aatcatctgt
    45781 tgtccaaccc tctttcacaa gatcaaggac gccagcatct ttgagcattt ttttattcaa
    45841 cgccatgtag aatggagcag agctgatagg atacatgtaa gctgtatctc ctgcttttga
    45901 ggcttgaatc aatttgtcat tgttaacatc tttggtaaac tcttctgtga acaagtcatt
    45961 caagtcagcc aatttcccat ttttaccata ttgaatgata cgacctggag catcaaagag
    46021 gacatcagga gctgttccag cttcaatagc agttgtgatt ttctcaggac cagatgtaaa
    46081 atcaatggtt tccaatttta ccttgatttc tggattagct ttctcaaagg cagcaatcaa
    46141 tttcttctca taggttccca caccatcttc agctttttct tgcgtgaaga ccgggaaagc
    46201 ccaccatgtg atttctgtct tagcagtatc agatttactt gcaccagcct ctttctggct
    46261 ctttccgcca caagctgcta gtcctaaaac agatgcacca agcatcgcta atgaagctaa
    46321 cttcttcatg ttcatcgtaa aatctccttt ttttgatgtg tgtttctagt ttgacaacca
    46381 ctattaggat ttgagcgctt cgataaaacg ctctgcaatt tccttaggcc ttgtgatggc
    46441 ccctccaaca acaatacctg ccacacctaa gtcattaatt ttcttggctt cttctgggga
    46501 atgaatcttt ccttcggcaa tgacagcaat gcctgctttg caaagagctt ctatcaatgc
    46561 cacatcagga cctgcttcct gacggctata cggggtgtag cctgacaagg tggttccaac
    46621 aaaatcaatg ccagcctgat gggccactag tccttcatca aaggtactaa tatctgccat
    46681 caaaagctga ttggggtact tttccttaac ttgtcgaata aagctagcaa tatccaagcc
    46741 atcatgtcgg tcacgcttgg tacaatccat agcaatcact gcaatattta aggcagctaa
    46801 ttgatccact tcggtcatcg ttgccgtaat aaaaggctct tgcggcgggt aatctttttt
    46861 gatgataccg ataattggta ggtctgttat ggcttgaatt tctttaatgt ctctaaccga
    46921 attagctctg atgccgacag caccagcttc ttgagcagct tttgccatca gtggcataat
    46981 acccccagtc tctgaataga gaggctcacc tggcaaagcc tgacaagaaa cgataatccc
    47041 accctttaac tgctccatga gcttttcttt ggttggttta tcaggcatag tttctactcc
    47101 ttgtgtttct tagttttaat aaaaataacg ttcacaaagt tattataaca aaaaataaag
    47161 cgctttcaat agcaatgaga cttttagaat ctactttcat tttttatatt attttctatt
    47221 atttggaatg ctctttcata caacaaataa aaaggtaagg agttgacacc atacttatac
    47281 attgcaaatt tccgattaga aaacgttaaa aaaccaagag cctcgagcac tcttggttta
    47341 ctttagttgt attttttgca attaagctga taatacttta cgtcctttac gacgacgtgc
    47401 agcaagcacg cgacgtccgt ttttagttga catacggtga cggaatccgt gtttacgttg
    47461 acgacggatt ttacttggtt gataagtacg tttcacagtg aatacctcct catagatttt
    47521 gtattcgttt agccggctat ttgtgatatc agttactaaa catactataa tattctatct
    47581 taaagagggt ctactgtcaa gatttatttt cgtttttcaa cagtttctct ctcatttaag
    47641 aggccgctca tttcataaag tgtctcttct ttgacactgt tcctttgcct taccgttgaa
    47701 accttatcaa tagcaacaat aatcaatgag atcagtaaaa caaacggtta agctggccat
    47761 acaaaaaatc ttcgatagct aaactaacta ccaaagattc tttttaggat ctaacgttga
    47821 agactgacta ccacatagcg gttagggtca ttgccttcag aataactatc aaccccttca
    47881 atggatgaaa cggttttatg aacgatttta cgctcactgt tactcatggg atccatggtg
    47941 taatcttgac cagattccaa aacgcgtttg gcaacttttt gcgtaaagtc aatcaaggtt
    48001 tctgttcgat gttccacata atcatggaca ttcaaggata ctgaaaaatt ttttgaatag
    48061 cggtcgtgca agaaattttg agctaacaac tgcaaggatt tcaagacctt accatggtaa
    48121 ccaatcacac gtcccgcctc tggcgtttca atctgcaaat tgatttggcg acgattgttg
    48181 ctggtttcaa cggtagcttc gatatccatt tcatagataa ttttagtcac ataatcggac
    48241 acttcctgag cagctttttc aatatctttg ctgaaaccat cattaccagc atcttggggc
    48301 acttctgatt cttcgactgg gattgacggt tgttgtgctt ttgtttcagt gactgtctca
    48361 gcaagattag aaggggtttg cgctggacta tcttcagaca tgagaggaac cactttggta
    48421 tcttctgctt ctaacctttg agtggctttt atttcttcag gttctacatc agcagaattg
    48481 accgcgggag tattttgacg attaatatcc tctggaacac ctcgagtggc ttttttatca
    48541 gccttataaa ccgtcttgtc gctgatacct tcgatatcaa cttgggctgg ctttttacca
    48601 aacccgagga aacctttttt ctcttttgaa atgactttga tatgcgcttt aaggcgtgat
    48661 aaccctaact cttgaagtcc tgtttcgata gcttcttcga ctgtttttcc tgtaaataat
    48721 accataacct aaactcctat tttctcttca ttgctttttt acgagcacga cgttcacgaa
    48781 gacggcgttc tttttcttca ttggcaagac gttgtctttc cgcaataatc ttaaaaggat
    48841 tgtttaataa cagtagttgt accacttgaa aggcattgga gaccgtccaa tagagcacta
    48901 ctccactagc caagttaaag cccatgaaaa agatcattag cggcatcaca taaatcataa
    48961 cagtcatcat gacatttttt tctttagccg ctagattggt caaccaagtg gacaagaaag
    49021 tgaagacagc tgccaaaact ggtaaaaggt acaaatgatc atgttgtgcc aattccaccc
    49081 acaagaaagt ccctgttttt aagaaagata cccgtgtcaa ggcttggaat aaggcaatca
    49141 taactggcat ctgaattaag aggggtaaga gactagcata agggttaacc ccatattttt
    49201 tgtaaagggc ttgactttct tcagccaact tcatccgcgt ttgtgtgtct ttaccagcgt
    49261 atttcctttg caattctcta agctcaggtt ggatgtcttg catcttctgg cttgatttga
    49321 tttgcatgtt aaacaaaggc atgagcatga gacggatagt aagggtaaaa agaataatgc
    49381 caacaccaat tgaaccatca aaggaaagcc attgaattgc tctggcaaat aagtaaacca
    49441 actggtccca accactagat gattgtgccg ttacctcacc acgaccacag gccactaata
    49501 atagaactaa ggggactatt cttgcaattt taatgttttt cttcactctc aaaacctttc
    49561 tcaagcaatt gtgctaactt taaaacatga tgtaaatttt gttgaagctc ttgatactcc
    49621 aaagactcga cacccttacg ggcaatcacc acgaaatcct ctgacttcag ctgatgccct
    49681 aatgccatga taacatgacg tatctttcgt ttgactgcat ttctggtgac tgcatttcct
    49741 atttttttac cgacagaaat acccacacgg aagtggtctt ggcctctatt taaatgataa
    49801 atgacaaatt ttcgatttgc tgtacttttt ccatccttaa atatggcttg gaaatctttc
    49861 tcacgcttga cacgataggt cttcttcaaa atttaactcc aatatctaaa ttattaccat
    49921 tataccacat cccctaaaaa attaaaaagc cctaaccctt tcagattaag cctctttctg
    49981 tactatttct agtttttgtg cttcaactgc ctcttgtcac tccatctttt cgtagtatag
    50041 ttcttctttc gacaaaggaa taaccttcag aaaacaacca taaaaagtca gaatccacaa
    50101 gacgtcagct acttatccct gtatttacct atcaaaaaac ccggcaagcc gggctttaat
    50161 actgatttta caatcagcta atgtgatatc caaacaaaga caactgacat cgtcattttg
    50221 tctgccgagc catcatatca aaaatactat ttgtttatgg agagagagaa aacaatattt
    50281 tgattgaatt ggggattgat tgctcgataa actcatgact tcgtaaatct ttatttacac
    50341 taattattat agcgaaaaat gtttcaataa gagcatcatt tcctgaaatg ttgctttttc
    50401 gtcctaaaat gttattgctc tcttaacttt agcgaagagc ctcccaccgt tcaaacagac
    50461 atttcatttt taatcgtgat accatacaag aatcaccatt ttcgaaataa aggagctgct
    50521 tactcttatc aattcgaaca accttatcta gattcacaag gtaggatcta tggcacaaaa
    50581 aaagtttcgg tgctactgct tgaatctcag atagattacc ataaaactct aatctttctg
    50641 tctgagtcca taaacaaact ttgtgaggag ttgtggctgt agcaaagtat aaaatatcct
    50701 tatagggcaa ttttaatctt gtctgtggag tctcaaataa aaacatgtcc tttgactcac
    50761 gactagacat catatcgtaa gtatatcgga tacattcttc gatttgttct ttaaactgtt
    50821 tttgaccacc tgctttatca ataaaatcta gagcggatac cttatattta aaagaaatag
    50881 gagcaaattc tgaatgagtg gtgacaaaca caataacggc attaggatct ttttgtcgaa
    50941 tagctgcagc taattcaagc ccacaacgag tatattcacc aatttcaata tctaaaaaat
    51001 acagctgatg gtctcctctt tcttggatac tctcaaataa tttttgagga gtcgagaaca
    51061 cttcaagctg attacatggt attctagtct cttttaagat gcctactacg atagattcta
    51121 tgcgtgtctg ctggataaaa tcatcctcaa gaataaaaat gttcatcata ctttatctca
    51181 tttctaacaa ttgtcttaat cgataatggt cacttttagt cgaaagcgtt atttgggggt
    51241 aactatctaa aacagtcaaa aagtgggctg agttctgctg ctgagcatca aagcgtttgg
    51301 ctatatccac acgattggtt tttgtgctat tttcaataat aaataattgc ttgttatctt
    51361 gtttaaagta tgcaatagat aaaaaaggac gtctactgcc tttggctgtc tcaatagcat
    51421 tgtccactag tccagtaaaa agtacaatta agtcgattaa cttaataggt aaatgatcga
    51481 taacatctgg aatctcaata taaagttcaa tacccaaata ctgagcttca agcaatttgg
    51541 aattcatgat actgcgaatc acagcctctt tgatattgtc taaagaagat atttcataat
    51601 ttgtgcgcat catagaagtt gccgattgct gaataaccgt gtcataaact ctagtaatca
    51661 gatctatatc accactatcg atactatctt ttagactaat taaaatattt tcagaatcat
    51721 gtttaactgt tctgatttct cggtaaagtt gctcaatcga ttgattgtaa ttttcaagat
    51781 acgcaatacg ttcattttgt gcttgtgtta atttttgtga cagctgatct ttagcaaatc
    51841 gatctaattt cacaataacc caaataaaaa tagctaaata aataaatact aaaatagacc
    51901 ggtactggaa atatagtgca agaaatccgc tttgcacagt taccaaaaaa tgggcgaaaa
    51961 agtagtaaga aaacatggca gtattcatcc aaaataccca ctttttcatc ttatcttcac
    52021 tgataaacct tattaagctt aagtcaatac tgaaaatgta gctaaacaga taaaatattg
    52081 gtaatacaaa aagataacat aactctaaaa gcttaaggtt attattaatt tgaccaatgc
    52141 taaatcctaa gacagctggt aaaaagaaag atccgatgac gcgaaacagt aattcgacaa
    52201 tcaagatagt aaagaaacca ttaaacatat gctcaaataa tttctttttc ggagcactta
    52261 acaaactaac aataataaag aacagttggt caatcaaaat gactttgtca aatatcatat
    52321 tagcaattac aaaactaatg cctataatgc taacccgttt ccagcttagt ttaatagcag
    52381 aaacctttgc aaaaatgacc cagctgttaa taaagatggt agcatagaat aaagccatac
    52441 tgtatataac catcatctat ccacctcctc ctttggcatg gtcaaggttt ggctaaattc
    52501 cttatcaaaa cttttagtcc gcaaggataa ataaggatac tttttgagaa tacgctgcgc
    52561 attagaaagg ccgataccac gttctgaacc ttttgaagaa tagccttctt caaagatctt
    52621 gttaatgtct accttttttt tagtcgtatt tgtcacaaca aacatctgat agtcacctaa
    52681 caaaaagtaa gcaattgaca tatgaggttg ttgtgcttca agagctgcct caatggcgtt
    52741 atcacaaaaa atagacatca acaatagtaa gtccaactca ggaatgtaag tctcttttat
    52801 attatctggc acttccacat tcaaatcaat acctgatttt tccgcactga taattttagc
    52861 tgacaataag ctcttaatcg atgagatatt aattttccta agcttcgaga tattatagtg
    52921 tttatcatcc cagtagtcgt tagcttcatg aaccgtttgg gcataaatat cttgaatctg
    52981 agtaatggat tcactcttaa tggcttgacc taaacgctct atacggctca ggtaatcact
    53041 ttgaaaagct cttacatctc gatagagttt ctcaagatgt ttcccataaa tctctaagtt
    53101 agtcatataa gcttgttgtt ctcttctcaa ctcattttta aggtattctt tagaactatg
    53161 attaaaataa gatagaagat aaactaaaag aagtataaac atcaaaaaca ataacttata
    53221 aggtgtggga acaaaaagag aatgatgaaa atgtaaaaag gggtccgtaa atcctaaaat
    53281 gacaaaaatg tccacataat aaaccaaaac aaaaatcagc aatgtttgat agaaattatg
    53341 cgatcgtttc gaatatccgg attggcatat catcttgtaa tcttttccaa tcatataatt
    53401 aataatagca aaacttggaa aaatcagcag ataagcaagc aagtcaaaga taatatgacc
    53461 cagataaata ccactcgaca aaaaaagata ggggataacg attgtaccca taaatcgaga
    53521 tagcaaatcc accaaaacac taggtgcaac agccaaaaaa agagctttca aagaaaataa
    53581 ttgcttggtt tcttgcctta aaacaactaa aaataataga ggatcaatta gcaatggcga
    53641 caaatacggg aactgattga aaaatagggc taaagccaaa atcgttagtt gtttccaaac
    53701 tggtaatgtg atatcagata gaaaggaaaa aatataaat
//
LOCUS       DAUGQX010000007        53306 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUGQX010000007 DAUGQX010000000
VERSION     DAUGQX010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53306
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.007"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(631..1179)
                     /gene="raiA"
                     /locus_tag="VIA51_000343"
     CDS             complement(631..1179)
                     /gene="raiA"
                     /locus_tag="VIA51_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEQ8682314.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
     gene            complement(1259..1924)
                     /locus_tag="VIA51_000344"
     CDS             complement(1259..1924)
                     /locus_tag="VIA51_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEQ8682315.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            complement(1896..3221)
                     /locus_tag="VIA51_000345"
     CDS             complement(1896..3221)
                     /locus_tag="VIA51_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8682316.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            3277..3909
                     /locus_tag="VIA51_000346"
     CDS             3277..3909
                     /locus_tag="VIA51_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEQ8682317.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNRQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            4037..4978
                     /gene="cysK"
                     /locus_tag="VIA51_000347"
     CDS             4037..4978
                     /gene="cysK"
                     /locus_tag="VIA51_000347"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEQ8682318.1"
                     /translation="MTKIYKTITELVGQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKANPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(4996..5373)
                     /locus_tag="VIA51_000348"
     CDS             complement(4996..5373)
                     /locus_tag="VIA51_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8682319.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(5373..6773)
                     /locus_tag="VIA51_000349"
     CDS             complement(5373..6773)
                     /locus_tag="VIA51_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8682320.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMCGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            complement(6810..7451)
                     /locus_tag="VIA51_000350"
     CDS             complement(6810..7451)
                     /locus_tag="VIA51_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682321.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVGDRTQAVVYAFRHHLVPQDDN"
     gene            complement(7444..8448)
                     /locus_tag="VIA51_000351"
     CDS             complement(7444..8448)
                     /locus_tag="VIA51_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8682322.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            complement(8445..9137)
                     /locus_tag="VIA51_000352"
     CDS             complement(8445..9137)
                     /locus_tag="VIA51_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEQ8682323.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            complement(9260..11158)
                     /gene="pknB"
                     /locus_tag="VIA51_000353"
     CDS             complement(9260..11158)
                     /gene="pknB"
                     /locus_tag="VIA51_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEQ8682324.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIIFENVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSINDSTAPGSNTELSP
                     SETTSQTP"
     gene            complement(11155..11895)
                     /locus_tag="VIA51_000354"
     CDS             complement(11155..11895)
                     /locus_tag="VIA51_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEQ8682325.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            complement(11933..13255)
                     /gene="rsmB"
                     /locus_tag="VIA51_000355"
     CDS             complement(11933..13255)
                     /gene="rsmB"
                     /locus_tag="VIA51_000355"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEQ8682326.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            complement(13245..14180)
                     /locus_tag="VIA51_000356"
     CDS             complement(13245..14180)
                     /locus_tag="VIA51_000356"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEQ8682327.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEHEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVVVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            complement(14242..16626)
                     /locus_tag="VIA51_000357"
     CDS             complement(14242..16626)
                     /locus_tag="VIA51_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEQ8682328.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFIIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKSDRDFLFEGKPSVLYSTLDREKEKIALKGIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERPIDRSESYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEAKILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMSIRHQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            complement(16691..17008)
                     /locus_tag="VIA51_000358"
     CDS             complement(16691..17008)
                     /locus_tag="VIA51_000358"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEQ8682329.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(17024..17659)
                     /gene="gmk"
                     /locus_tag="VIA51_000359"
     CDS             complement(17024..17659)
                     /gene="gmk"
                     /locus_tag="VIA51_000359"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEQ8682330.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNSFKAK"
     gene            complement(17769..19376)
                     /locus_tag="VIA51_000360"
     CDS             complement(17769..19376)
                     /locus_tag="VIA51_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEQ8682331.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            complement(19506..20401)
                     /locus_tag="VIA51_000361"
                     /pseudo
     CDS             complement(19506..20401)
                     /locus_tag="VIA51_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            20603..21790
                     /locus_tag="VIA51_000362"
     CDS             20603..21790
                     /locus_tag="VIA51_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8682332.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            21814..22464
                     /locus_tag="VIA51_000363"
     CDS             21814..22464
                     /locus_tag="VIA51_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8682333.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADVALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            22466..23125
                     /locus_tag="VIA51_000364"
     CDS             22466..23125
                     /locus_tag="VIA51_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8682334.1"
                     /translation="MGTSTTVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            23158..23937
                     /locus_tag="VIA51_000365"
     CDS             23158..23937
                     /locus_tag="VIA51_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEQ8682335.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            24008..25339
                     /locus_tag="VIA51_000366"
     CDS             24008..25339
                     /locus_tag="VIA51_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEQ8682336.1"
                     /translation="MEIIGSLGVLVGVIVIIYLYVKEVNIIIAAPLATSLVILFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVAFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     VILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIVPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIVIAFDLFS"
     gene            25413..25895
                     /locus_tag="VIA51_000367"
     CDS             25413..25895
                     /locus_tag="VIA51_000367"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEQ8682337.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(26040..27509)
                     /locus_tag="VIA51_000368"
     CDS             complement(26040..27509)
                     /locus_tag="VIA51_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682338.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKLYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAVQDQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(27523..28677)
                     /locus_tag="VIA51_000369"
     CDS             complement(27523..28677)
                     /locus_tag="VIA51_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEQ8682339.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAAMIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKVNGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            complement(28740..29108)
                     /gene="rnpB"
                     /locus_tag="VIA51_000370"
     ncRNA           complement(28740..29108)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VIA51_000370"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(29122..29448)
                     /gene="gpsB"
                     /locus_tag="VIA51_000371"
     CDS             complement(29122..29448)
                     /gene="gpsB"
                     /locus_tag="VIA51_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEQ8682340.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            complement(29570..30085)
                     /locus_tag="VIA51_000372"
     CDS             complement(29570..30085)
                     /locus_tag="VIA51_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEQ8682341.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNKEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            30166..30765
                     /gene="recU"
                     /locus_tag="VIA51_000373"
     CDS             30166..30765
                     /gene="recU"
                     /locus_tag="VIA51_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEQ8682342.1"
                     /translation="MVNYPHNLIRQKVSSVQKQNKVDFANRGMSFEAAINATNDYYLS
                     RQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAKETR
                     QKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQIDNGS
                     KSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            30752..32917
                     /locus_tag="VIA51_000374"
     CDS             30752..32917
                     /locus_tag="VIA51_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8682343.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNGSHPSTDDKKTTH"
     gene            complement(33384..34721)
                     /gene="pepC"
                     /locus_tag="VIA51_000375"
     CDS             complement(33384..34721)
                     /gene="pepC"
                     /locus_tag="VIA51_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEQ8682344.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQY"
     gene            complement(34906..35730)
                     /gene="nadE"
                     /locus_tag="VIA51_000376"
     CDS             complement(34906..35730)
                     /gene="nadE"
                     /locus_tag="VIA51_000376"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEQ8682345.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKAVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREEASDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(35732..37186)
                     /locus_tag="VIA51_000377"
     CDS             complement(35732..37186)
                     /locus_tag="VIA51_000377"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEQ8682346.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVKEFDAIPLLVDIFVKGELVYQLPTLAEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMALIDNIRKDAYGKSE"
     gene            complement(37357..38736)
                     /locus_tag="VIA51_000378"
     CDS             complement(37357..38736)
                     /locus_tag="VIA51_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8682347.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(38905..39822)
                     /gene="trxB"
                     /locus_tag="VIA51_000379"
     CDS             complement(38905..39822)
                     /gene="trxB"
                     /locus_tag="VIA51_000379"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEQ8682348.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFSS"
     gene            complement(39886..40110)
                     /locus_tag="VIA51_000380"
     CDS             complement(39886..40110)
                     /locus_tag="VIA51_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEQ8682349.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(40214..40957)
                     /locus_tag="VIA51_000381"
     CDS             complement(40214..40957)
                     /locus_tag="VIA51_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682350.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            complement(40957..41760)
                     /locus_tag="VIA51_000382"
     CDS             complement(40957..41760)
                     /locus_tag="VIA51_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8682351.1"
                     /translation="MTSVFLTSGWAFYDYLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(41955..43298)
                     /locus_tag="VIA51_000383"
     CDS             complement(41955..43298)
                     /locus_tag="VIA51_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8682352.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKDSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            complement(43456..44466)
                     /locus_tag="VIA51_000384"
     CDS             complement(43456..44466)
                     /locus_tag="VIA51_000384"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEQ8682353.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(44468..46723)
                     /locus_tag="VIA51_000385"
     CDS             complement(44468..46723)
                     /locus_tag="VIA51_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8682354.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(46727..47050)
                     /gene="ftsL"
                     /locus_tag="VIA51_000386"
     CDS             complement(46727..47050)
                     /gene="ftsL"
                     /locus_tag="VIA51_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEQ8682355.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(47055..48068)
                     /gene="rsmH"
                     /locus_tag="VIA51_000387"
     CDS             complement(47055..48068)
                     /gene="rsmH"
                     /locus_tag="VIA51_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEQ8682356.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(48382..48522)
                     /locus_tag="VIA51_000388"
     CDS             complement(48382..48522)
                     /locus_tag="VIA51_000388"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682357.1"
                     /translation="MTNEREKEEAKVTLEELLHQIQVIHLELKIVRNWGYFVFFWRWY
                     AG"
     gene            complement(48542..49792)
                     /locus_tag="VIA51_000389"
     CDS             complement(48542..49792)
                     /locus_tag="VIA51_000389"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEQ8682358.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDIATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     YTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(49785..50606)
                     /gene="proB"
                     /locus_tag="VIA51_000390"
     CDS             complement(49785..50606)
                     /gene="proB"
                     /locus_tag="VIA51_000390"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEQ8682359.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAYYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVANITQEIIASAGGAGSKF
                     GTGGMLSKVQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVRHD"
     gene            complement(50671..52299)
                     /locus_tag="VIA51_000391"
     CDS             complement(50671..52299)
                     /locus_tag="VIA51_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682360.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMI
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVVQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKVKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLMDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGDGQWLTMGLIFGNLIVAGVLGFGAVIIANIIQQ
                     PLLISILLSCLILMVLGLAQLWIQKTFWKSLERL"
     gene            complement(52304..53038)
                     /locus_tag="VIA51_000392"
     CDS             complement(52304..53038)
                     /locus_tag="VIA51_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682361.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            complement(53072..53305)
                     /locus_tag="VIA51_000393"
     CDS             complement(53072..53305)
                     /locus_tag="VIA51_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8682362.1"
                     /translation="MRQAYDYPENRENVALSQLLLAASNRLIKHSNPLLVAYQLNQDV
                     DNYLLDNDILLPKSLCRFKQSLEKYILEEASLV"
BASE COUNT        16106 a        10981 c         9383 g        16836 t
ORIGIN      
        1 tataagattg tcaatagctt ttttattttt ttataaaaat aagtgttagg ttgtactgat
       61 aaaacgctaa tacaaaaaaa gtttaaccct tctgtgatgc tttctcagtg ataggcttat
      121 ttggaactat tttgttataa tctgatcttg cacgcacgtc acataaccta tattttaagc
      181 aaacgtaagt gcttaaatct tttatggaaa aacaattcag attgctgcca aagattgtgc
      241 tattattttt agttagaaaa aattctattt ttatttggtg tcagaaagtc tttgaccttt
      301 ttttaaaaag taaaaattct cttatgatac catgttcgtc atgagttttt tattgttaaa
      361 tggaaaaaga aaaaaacgcg ctttatattc tgaaaacgcg ctttttcata tttttttgag
      421 aatttctagc ccagaattgg gactaatctt ttttcaaact aattttacgt aagatttact
      481 taaagaggaa ctgtaataga tacttttgtt agcataatga ctgtcgtatc tatcacttaa
      541 tctcattttc atcatgtcac ctctaaacat gaatagcttt ttcccacttt taaaatacgt
      601 ataatcatcc ctgtaggttt tagttgtgaa ctatttagct tctattaatc ctaggtttcc
      661 atcttcgcga cggtataaaa tgtttgttgc gccatcttca gaatcagtgt agataaagaa
      721 atcatgtccc aatagttcca tctgtaaacg cgcttcttca acatccattg gttttaatgt
      781 cacattttta gtacgtacaa cttgtacttc tggtatctca tcgacttctt cagcttcaaa
      841 ctcagttgta aagacttgac cagttggaac cttttcgcga tgttttttag caattttggt
      901 tttatttttt ctaatttggc gttcgatctt atcaacaact aaatcaatag agccgtacat
      961 atcctgtgaa acatcttcag cacgaagggt tactgaatct aatgggatcg ttacctcaac
     1021 ttttgaagat ctctcccgat aaacttttaa attaacacgt gcatctattt cttggtcttt
     1081 agcaaaatat ttttcgattt tagtaagctt tgattctaca taatcgcgaa tagcttctgt
     1141 cacttcgata ttttctccac gaatactgaa cttaatcata ggatacctct ttctcgcgct
     1201 tgaagcgctt actttatctt taatactatt atactgcttt catgaaaatt tgcaagtttt
     1261 aacgtgcaat tgacaaactt ttaatgtcac tatttgctac tttagccaat tgttttctaa
     1321 gagcgataat tgtactacca gtagtataaa tatcatctac tataaggatt ttatcaggaa
     1381 tgtttgatac ttttagtagt cgataagatt tttctactaa taatctctct ttttttgttc
     1441 tggaagattg gtgagtatta tctagctttt caaaaagaga aaggtagcta acattagctg
     1501 cctcaagaat agcgctcact tgattaaatt gtctttctcg aaaacaaccg ggacttacag
     1561 gaaccgggac tgggatatag cctttatagt acttggtgat aacatcggca agttctactg
     1621 caaaaacttt tcttaataaa tagtctcctt gaaacttata ttgactgaag tatgctttca
     1681 tagcagcatt ataacaatat aagcttctat gatttacatt gtatcctttg ttttcccatt
     1741 ttagacaatc tcgacaagct attatatctg agtttgcaca acatgtcgca caaacacttt
     1801 ttcctatctt ttgaaagctt ttttgacatt gttgacaaat cggtgaagag atacgtctta
     1861 aaaagatgat ttctgtaata cttattggtg tttgactaat ttgttgacat agtagacaga
     1921 tcatgcgaat accctttata attcatttct ttaatctctt ttcttgctag tagcattgct
     1981 ttactgatac cttcatgaaa gaaatataac gttccgtctg gtctgtctat agatcttcca
     2041 actcgtccag caatttgaac aagactttgg gaactataga cacgatgatg agacccaaga
     2101 acaaaaacat caatttgggg aaatgtcaca cccctttcta aaattgatgt tgtaattaaa
     2161 atcgtttttt tcccttgacg aaaagctgtg atatcttctt tcctgttttg tgattgacta
     2221 gaaacacaag ctatttgttc ggcgggcaat aactctttta agattgctgt aacagattct
     2281 gccattataa tagtgggtag aaaaattaaa aggggatagc ctgtttttct ttgttttttt
     2341 aagtatttta aaattttaag aggaagtttt tgccgatgta tcattttaaa tagattaaaa
     2401 cttcttataa attttggaat aactaatggc ctattatgaa agcgtctcgc caatgtcagc
     2461 ttgactactt ctcccttgtt tacctttctt tctaaagttc tagttgaagt tgcagttaat
     2521 aaaatctttg cgccaccttc ttttaaagcc tgacttgcag cataatgaag ttgaatatta
     2581 tttacaaaag ggaatgcgtc tacttcatca ataattaaga gatcaaaagc cttgtgaaat
     2641 tttagcagct gatgcgttgt ggctactata ataggagctc tttgataagg aagagactct
     2701 gcgtgcatta aacagatgct gcaggagaag gcttgggata aacgagtagc cacctctaca
     2761 caaacatcta ctcttgggct ggcaatgcaa acccagccac ctgtgttaat taccgcctca
     2821 atcgcagcat aaatcatttc tgtttttcct gcaccagtta cagcatgaac taatgttgtt
     2881 ttttgatttt gcatattgat taataattgt tgggaaatca tctcttgata agcagttagt
     2941 tgaccgcccc aaaccagata attacctttt ggaaaatgca taggtgggat agcatagagc
     3001 aatttatctg attgatttcg tccaaagaca agacaaaatc ggcaataata ggctccactt
     3061 ggcaatcgtg cttcttcatc aagctgatag tgacaacgtt gacaaatcat ttttcctctc
     3121 aatattacta cactttttaa aggttgagca agctgctttg ctgaatctgg taactggctt
     3181 tctagcaaca accgtccata actattttca atagactcca tactttatta ttcgcttttt
     3241 tttgctaatt tttatctttt cttgtacaat ttttttatgg aacattttaa gacaatcaaa
     3301 gccagtggtt ttttcgaaga aagtattaaa aaatctcgtt tcatttgtca tatcaaacga
     3361 gtgagcactg aagaagatgg taagaatttt gttaatgcta tcaaaaaaga acattacaaa
     3421 gctaatcatt cctgctttgc gatgattatc ggtaacaaca gacagatcaa gcgctcaagt
     3481 gatgatggtg aaccttcagg aactgctgga atacctatcc tttctgtgtt agaaaagcag
     3541 tgtttaacaa atgtagtagt tgtggtaacg cgttactttg gtggtattaa attaggaaca
     3601 ggtgggttaa tcagagcata ctctaacatg accgcaacag ctattaaacg atttggcatc
     3661 attgaagtta aacagcagat aggactagaa atcacacttt cttatcccca atatcaacta
     3721 tactctaact tgctagatca attggcttta accgaaacag aaactaagtt ttcagacacg
     3781 ataaagacaa cactttattg tgatactgaa cgtgtggaaa atctcattga tactttaaca
     3841 aattattatc atggtcagat aagctgtgag aaaatcggat ccaaagttat tgaattcccc
     3901 tgtgattaat catcaacaaa agtgatatgg ctttattatc agagtgatag taaatctgta
     3961 ttttacttta ataatatctc tccttatact taaatacaca gcgtatttat tttgtatcaa
     4021 gaaaagaggc taaactatga ctaaaattta caaaactata acagaattag taggtcaaac
     4081 acctattatc aaacttaacc gtttaattcc aaacgaagct gctgacgttt atgtaaaatt
     4141 agaagctttt aacccaggat cttctgttaa agatcgtatt gctttatcga tgattgaagc
     4201 tgctgaagct gaaggtctga taagtcctgg tgacgttatt atcgaaccaa caagtggtaa
     4261 tacaggtatt ggtcttgcat gggtaggtgc tgctaaaggg tatcgagtca ttattgttat
     4321 gcccgaaact atgagcttgg aaagacggca aatcattcag gcttatggtg cagagcttgt
     4381 cttaacacct ggagcagaag gtatgaaagg ggctattgca aaagctgaaa ctttagcaat
     4441 agaactaggt gcttggatgc ctatgcaatt taataaccct gccaatccaa gcatccatga
     4501 aaaaacaaca gctcaagaaa ttttggaagc ttttaaggag atttctttag atgcattcgt
     4561 atctggtgtt ggtactggag gaacactttc tggtgtttca catgtcttga aaaaagctaa
     4621 ccctgaaact gttatctatg ctgttgaagc tgaagaatct gctgtcttat ctggtcaaga
     4681 gcctggacca cataaaattc aaggtatatc agctggattt atcccaaaca cgttagatac
     4741 caaagcctat gaccaaatta tccgtgttaa atcgaaagat gctttagaaa ctgctcgact
     4801 aacaggagct aaggaaggct tcctggttgg gatttcttct ggagctgctc tttacgccgc
     4861 tattgaagtc gctaaacagt taggaaaagg caaacatgtg ttaactattt taccagataa
     4921 tggcgaacgc tatttatcga ctgaactcta tgatgtacca gtaattaaga cgaaataaaa
     4981 aagggtttgg aactactaag gttccagact ctttttagtg ttctttttta aaaactgcag
     5041 gctttcttca atccactgag gtaactgctc ttcaagtggc ctaaagccaa tcttgtgccg
     5101 actgttggaa taacgatgac gatggaaaaa atgctgtttt tcttctgcta aggtccgcat
     5161 agataaactt ggctttttac tatattcatc aatatcaatt acttgtacta aaacctggtt
     5221 gcctatagcc aataattgat caatatcgtc aataaatccc gtttttattt ctgaaatatg
     5281 aatgagacct gttgtcccat tttcaagggc aacaaaggct ccgtatggtt taatcccagt
     5341 gatggtgcca tgcagtttgt cgccaatttt cattagtcaa atacctcgat tgtttcaatg
     5401 ataacgtctt ctttaggttt atcctgtgcg ccagtttcaa cgccagcaat caaatccaaa
     5461 acttggaatg aagtttcgtc cacaagctga ccaaagaccg tatgacgacg atcaaggtga
     5521 ggagttccac catttgcagc gtaagaagct gcaattggag ccggccaacc accacgttct
     5581 agttcttttt tggcataagg aatcttacta ttttgaacaa taaagaactg actgccgtta
     5641 gtatttggtc ccgcattagc catcgacaag gccccacgga gattatagag ttcatccgaa
     5701 aattcatctt caaaactttc accatagatg gattgtccac acattcctgt tcctgttgga
     5761 tcgccccctt gaatcataaa ttcaggaata atacggtgga agataatccc atcatagtac
     5821 ccttctttag ccaaacctaa gaaattggct actgttttag gagcatgatc tgggaacaag
     5881 accagggtca tatcgccatg gtttgtttta atggttgctt ttggtccttt atggtttggc
     5941 aaatccaatt gtggaaactg taattctttg tcaatcaatc ctaattcctc caaggcatat
     6001 aaaatgccat cttcttcaac tttttttgtg ataaaatctg ctttttcttg cagtaatgga
     6061 tgtgatactc ccattgcaat actgatacca gcatagtcaa ataactctag gtcattgagt
     6121 tcatctccaa aaaccaaaat attttcaggt tttaatccta aatggtcaac tacttttgaa
     6181 acacctagcg cttttgacgt acctttcaag acaacatctg atgagttatc gtgccatctg
     6241 accaaacgaa ggtgctctgc taattcagca ggcaactgca agccatctcc cttgtcctcg
     6301 aaagtccaca tctggtaaac atcatgatac tcattataat ccggacagac ctctagttga
     6361 gcgtagacat tatcaatagc attgctaatc atgtcatttc gagcggacaa caccgcttca
     6421 tgacgacccg ccattccata aaaaatgccc atatcatccg cccatttttt ataggccaca
     6481 acaacatctg ctggaatcgg agcttggaaa ataatagttt tagcatcgtc tttgacataa
     6541 gctccattta atttgacaca atagtcagca tgtaaatctt gaacttcttg tggaacaccg
     6601 taccgagcgc gacctgaagc aataccaacc aagatgcctt ttgccttcaa agccttaaat
     6661 actctttgaa tcgactcagg catataaccc gtatctttga ccctcaaggt atcatcaata
     6721 tcaaagaaca ccattttgat ttttttagct ttgtatttta gttttgcgtc catactttcc
     6781 tccaatttgc tataccctat attatagcat taattatcgt cttgggggac taaatgatgt
     6841 cgaaaagcat agacaaccgc ttgggttcgg tcaccaactt ctaacttggc tagaatattg
     6901 gacacatgtg ttttgacggt ttttaaggaa ataaagagtt catcagcgat ggtctgatta
     6961 tcataccctt tagctaaaag gtgtaaaatg tcatactcac gcgctgttag ttcctcatgc
     7021 aagtcagggt gttgatcatg cgccttaatt tttttgtcaa cttctgtttc aatagctaac
     7081 tctccctttg aaaccttgcg aatggcattt aaaatttcag ccgcactcga tgtttttaac
     7141 atataaccct tcgctcctgc atcaatgaca gggtatatct tttcattatc tagataggaa
     7201 gttaacacaa gtaccttagc ctctttccat ttttttagga cttctaaagt tgcctcaaca
     7261 ccgcctaact ctggcatcac tagatccata accaaaacat ctggcttcaa agccaatgcc
     7321 aaatcaaccc cttcacgtcc attagaggcc tcaccaacga catcaatatc agcttgtaaa
     7381 ttcaaaaaac tcttgagtcc catgcggacc atttcatgat catcgaccaa tatcactttt
     7441 atcttactca tcgtcatctc ccttcactat cggcagtcta atatccatgg aaactccttt
     7501 gcctttttga ctaattaaat gtaggtttcc tgctaaatca ttgacacggt cttcaatatt
     7561 cttcagacca taactcaaat cccttacctg atccatatca aatcctacac catcatcaat
     7621 catcttcaat tgtaattctg ttgaggtttg attgagataa acttcaattc gactagcttt
     7681 agcatgtttt aacgtgttgc taatgaattc ttgggcaatt ctaaaaagat tatcttccat
     7741 tgttttagga agctgagcaa tggtttcctt ataaatgact tcaatatcac ttttatctgt
     7801 taattcctta agaatcatat gaaggccctc agataaagtc cgattagcta gctcggtagg
     7861 tctaagatgc aaaaggagaa tgcgtagatc attttgagca ttttgcaaca ttgcttcaac
     7921 cgttgttaac tgtgtttgta attgtgtttt gtccagttgt tccaaactca tcgaaattcc
     7981 tgataaaatc aatgacgaag cgaatagctc ttgactgact gtgtcatgta aatctcttgc
     8041 aattcgtttg cgctcttgtt ttacaacttc ttggctatca agaatataag cactttcttt
     8101 cttttgcatg ttagcagtca ggtgagacat ttttttagaa agtcgactta aattagtatt
     8161 gatttctgat gtctcatcta gatagagtcg tcgattattg agaatatatt ttagattttg
     8221 gttgatgtta cgcttactgt tatcatccat aataatccac aataacaaca ataataaagt
     8281 cacagaaaca atcaacaata aaatcgaaaa ccctagacgt tcgacctgcc ataaatgatt
     8341 gcgaaggtag ttaaaagtga ttcctaaatt atccatgacc acaaaaacaa tagataaaat
     8401 ggtaatggtt gagtagagcc aaacaagagc atagtaacgt tttttcatcg cctatccacc
     8461 tcaacatttc cggcaatagt tgtaacgata attttgactt ttttaaggga ttggttatcc
     8521 gtttctttta acttaataga ttcgttgcgc aaatcatatt gctgacatct aaaaaaatca
     8581 acgcttccgt atatggaact aacatctaaa gtaacagtga catcaatagg taccaatata
     8641 gtcgtatttc caaaaatttt acgtatcaca atgatattat ccattcctgt cacaataaca
     8701 ttggttaagt caaccgtgtc atttcctgag attcgaatga tgttaatgtc atcaaaacaa
     8761 taataatcac tttcataatt agcagtacca atccattgat gcttggtatt gttcacttca
     8821 atcttttctt ccttgaaacg aatcaaggca aagcgattct tctttttgac ttgtgaaaaa
     8881 tggttaatga aaatgtaaac tatccccaaa agaacagcca tgataatgta gggattaagc
     8941 atgaaaatta aaaaaagaaa caataaactg acagttagta aaaaattatt gcggctatct
     9001 tggttataaa agcgtaatgc taataagata agaactagaa ttaggataaa acttgataaa
     9061 tcattatcca agattgtcat gatacccata gctagcagta tacactcgat aagtaaaaag
     9121 aattgaaatt ttttcattag tttcccctta tttctttgta ttttatcaga attcctggaa
     9181 aattgcatct ttatatgacg agtagttaaa aagaatagtt agtggcatgc cagtaaaaca
     9241 tgagactaac tattctttgt taaggtgttt gagaagtagt ttctgatggg cttaattcag
     9301 tgttgctacc tggtgcagta ctatcattta ttgaagaact gtttgaactt gacgttgaac
     9361 tcgatgagct actagaagag tgtgtttctt ctggataaag gtaaagacta atctctcctt
     9421 tatcagacaa actcaaagac gttccatagt aaggagattg accactgaca atagctttag
     9481 aactaggaga atgaattggc acaaagcccg ttgctgagct agagcttggc acataagctt
     9541 ttattctaga tgcatctata cctaaagctg ttaaggtatt gactgcatct gcataactat
     9601 attctgttac cataggcata gtgatcgtat cactaacagc aacactgagc gtaattttag
     9661 actttccgtt tggattaaat ttatcacccg cacttggcga ttgactgatg actgtatttt
     9721 caggatattc attagttaca atgcgctcaa ttttgatttt tgattttgga acaccataag
     9781 tttctatcaa actattcata gcttcttgat aatctagtcc tttgtagttt tccatgtcaa
     9841 aacctttgtt tccaattgac acataaagcg taatgcttga gccttgcctc ttagctgttc
     9901 ctgctttagg atctgttcta actacatttc cctcagcaac cgtatcactc tcaatttgcc
     9961 tgattttacc cacttttagc ccaacatcat acagttcttg tttggcaact ttaagactag
    10021 tgcctgctac attaggaact ttcacagaag ttggtttagt tagtataaga taagtaaaga
    10081 gtgctacacc tacaataaag aaagaaaaaa gaattttgaa taaagtacct aaaaaacgac
    10141 cacttttttt ctttttggtg gggggctgta aagcatctgt ttgattagtt tgatctaatc
    10201 gactttcctg tgttaacact gttggggtag ggggagacaa ttttacagaa gcggtgggac
    10261 ctgaggccac tttggggagg ggtttggtac tttcaacatt ctcaaagata atcttacgct
    10321 cccgactacg attataacta agcgccgtca ttaagtcacg actcatttca aaggttgacc
    10381 cgtaacgatc acttaatttc ttggctgttg ctcgaataac aacattctcc aaagcttgtg
    10441 gcacattgtg gttctcctcg ataatagatg gaagaggctt ttgaaaatgt tgcaaggcaa
    10501 tcgtaacagc actatcgccg tcataaggga tatggcctgt caacatctca aagagcataa
    10561 tccccatcgc ataaatatca ctttgaatcg tcgctttgga gccgcgagcc tgttctggag
    10621 acaagtaatg aacactgcct aacatcgaat tagtttgtgt caagcttgtt tctgcaaagg
    10681 ctactgcgat gccgaaatca gttactttga caacaccctc cttagttagt aggatatttt
    10741 gaggttttaa atctctgtgt acaattcctt tttggtgggc taaagtcata gcagaaagga
    10801 cttcttccat aattctaacc acttcattat tagataatgg agcatgattt tgaatgtatc
    10861 tctttaggtc agcaccatcc acatattcca ttactaaaaa ttgctgtccg tcttcttcac
    10921 ctatatcccg gatggcaaca atattgggat ggttcaattc agccatggcc cgcgcttctc
    10981 gttggaaacg cgcaactgct acctgatctg tttgataatt ggtacgcaag accttgattg
    11041 caacgtcttc attatccaag atcaagtcat ttgctaaata aacatccgcc ataccaccgc
    11101 ggccaataga tttcagaatg cgataacgac cagcaaataa tttgccaatc tgaatcattc
    11161 gacgtcctca ctttcgttat gaaccaaagc gattgtaata ttatctaggc ctcctcttag
    11221 gttagctaag tcaatcattt cttggttttt ttcatcaaga ctaaccttac tgcccaagat
    11281 agtcacaatt tcatcatttg aaatcatatt ggttagacca tcactgttaa tgacaagata
    11341 atcccctggc tccaaaaccc tcactcctaa atcaggctct actggggaag cttgaccaat
    11401 agattgagtg ataatatttc tttgtggatg gctagcagct tcttcttctg tgatctgtcc
    11461 tgccttaacc aactcattca ctaaagaatg atcactggtc aataaggtat aatgcccatc
    11521 atggacaaga ccaatccgtg aatcaccaat atgagcataa atggcgctag attcaactaa
    11581 agctactgct tcaacagtcg ttcccattcc tttaaagtct tctgattggc ctagatcata
    11641 aatccgttga ttttctgact ggatagtttc aaataaccaa tctctaatct gacttaactc
    11701 tgtgaagtct gtttttaccc attctcttcc caggtctgtg actgtcatct cactggcaat
    11761 atttccagct ctgtggccac ccataccgtc tgctaaaatc actaaagtga tgcctttttt
    11821 attatcaaac ttattgataa aatcttgatt gtttgagcgt ttttgcccaa tgtctgtttt
    11881 taatgaaatc ttcatacgtt ttttctgact cagtcagttt cctcctaaaa tactacaaga
    11941 ctcgtctgac ttgtccaata aagaagccat cagtctggta ttgttctggt gtgataataa
    12001 gataaccatc cttgacaata tctgcttgtg tatggttcag ttttacttgt tcaaaattag
    12061 gatgactctg taaaaatgct tcgatgactt gacgattctc ctcatcaaaa atagtgcaag
    12121 tactgtatgt tattatacca cctttacgca aggtttgaca aacactagac aatatctcta
    12181 gctggatagc ttgcagagca ttgaaatctt gactttcttt attatatttg atatcgggtt
    12241 ttcgacgaat caaaccaatt cctgagcaag gagcatccac caaaatctta tcaaagctat
    12301 ccttttcaaa atgacgatga acctctctgg catctagttt tcttgtctca atgttatcag
    12361 caactcctaa gcggttagca ttttccttca ccaactctag tttatgatca tagagatcta
    12421 aggcaataac tttacctgtt tttaagtaag atgctatatg agaggtcttg ccccctggag
    12481 cgctacacgc atcaagaatt atgtcgtcac cgtcaatgtt taaagtagga gctacaagct
    12541 gactgctttc atcttgaata gtgatgtccc catttgtgaa ataatcactg gctgcaaaat
    12601 gacctgacgc tttggttaaa ccagttgctg ataaaaggga acgttctgca tctaaagcct
    12661 cagcaacttc ctctagcttc aaagggtctg tcacgcgaat actagcctta ctacgcacaa
    12721 ataaactttc catgatggcc actgatctgt cagaaccaaa ttggtcttct aactttttaa
    12781 ccaaccaaac aggcagtgaa tacttgaccg aataatactt atttcgacgc ttaattgttt
    12841 ccatatctgg gagaggatgg ctggtgaatt gacgtaaaat agcattgaca aacttctctg
    12901 cacctttttt attgccacga tttttggcaa taccaaccgc atcgttaaca atggcatgcg
    12961 ctggtaactt atctaaataa gtcagttgat aaagactgag cataaggaga taataaaccc
    13021 atttgtccaa tttatctcgg tctttgacat aatgggctaa ataccattcc aagctaattt
    13081 tacgtgaaac ggtaccatat acaatctcag ttaatagagc tctgtcctta gcagataaag
    13141 ctttattgct tagttgctga ttaagcgcta tgtttgtgta agccccctga tcaaaaatag
    13201 cttcaatgac aaggagggct ttgcctcgcg tacttttttt ccaattatct gccaatgatg
    13261 tcccctactt caagttttct accaatgccg tttaaaaagt ctattattga cattttaggt
    13321 ttaccagccg gttgcacaac gatcaaggac aaagcacctt gtccagtagc tattaccaaa
    13381 gattttttgg ttttgacaac aacttgtcca ggtaatccct ctccttcagc tagttgagct
    13441 tcgtaaattt ttaaacgttg cccctctaaa aacgtatgcg ctaccggcca agggttcata
    13501 cctcgaatat gattgaacac ttcttgatta gacattgtcc aatctaattt ttcatgttct
    13561 ggagagatat taggtgaaaa agtagcttgg ctgtgatctt gaggaatagg ttttaattct
    13621 ccagaaagat aagctggcaa actatccaaa agtaagtctc gaccaatgat ggctaatttc
    13681 tcaaaaagag tacctacatt atcggtttca agaattggag tgcttgcttt agcgaccatg
    13741 tcacctgcat ccatttcttt aatcatttcc ataatagtaa cgccggcctc tttatctcca
    13801 ttcataatag cataatggat aggtgctcca cctcgatatt taggtaacaa tgatgcatgt
    13861 acattaatag caaatgaaac tgaatcaagt aatattgttg gtaaaaattg gccaaatgct
    13921 gctgtaataa taccatctgc accaagtccc ataatctcaa tgagttcttg agagcctgat
    13981 aatttttccg gctgatagat tgatattcca tgctcaagag ctaattgctt tacaggtgtt
    14041 accttaatat cttttttgcg tccaacagct cgatcaggct gagtaaccac tcctaaaatc
    14101 tcataggcag gattatctag caagcccttc aatacagttg ctgaaaattg gggagttccc
    14161 ataaataata attttatcat gactttcctc tttgtatttt tattatatca taactgatca
    14221 tcctagattt agtgatttac cttataaaaa ttgttgcggt tcacaatcaa taattagttt
    14281 taaatgacga ttatctgctt cttgactcca atcaagaata cgattgagcg tctcttctag
    14341 gttatcttca aaacggtatt ttaacaaaat ttgatagtgg tataaattgt gtgttctagc
    14401 aattggctta ggagtcggtc ctaatatttt aatattatcc gataagtgac tctttagcag
    14461 ttctgtaact tgataagctt tttttacaac cgatgcttct aaacgatgcg aaagcgtaat
    14521 acccactgta aagtagtaag ggggataagc catttgatga cgaatagaca tctcataacg
    14581 gtaaaaagct tcaaaatctt gtttcttagc taattgaata gcatagtgat cgggattata
    14641 agtttgaatc aagacctctc ctggcttatg ggcacggcct gcccgaccag caacctgtgt
    14701 taacaattga aacgtttttt ctgacgctcg aaaatccggc aaatttaagg aagtatctgc
    14761 atttagtacc ccaactaaag tcacatttgg aaaatccagt cctttggcaa tcatttgcgt
    14821 ccctaacaaa atatctgctt cctggcgacc aaaactatct agtatggttt tgtgacttct
    14881 tttttttcgt gtggtgtcaa catccattct caagatctta gcttctggaa taaccccttg
    14941 caattcatca aaagcttttt gagttccagt gccataatag cggatactat tgctatgaca
    15001 ctcaggacaa gtaattggga taggtttttg aaacccacag taatggcaat tcatagtttt
    15061 agtatccatg tgaagggtta aagagatatc acagttggga catttgtcca cataaccaca
    15121 gtcccgacac atcacaaaac tagaataacc acgtctattt aacattaaga caacttgttc
    15181 ttttttaacc aaacgttctt taatcttatc aatcaaatat ggggtaaaat tactaactgc
    15241 ttgctgtcca atataatcac gaaaatcaac aatcgttact tctggaatct tagcaagagg
    15301 gtttgctctt tgcgttaatt gaataaaatg atagacaccc ttactagccc ttgctcggct
    15361 ttcaatactt ggcgtagcag agcccataac cacaactgct tgatggtgtt tagctctgag
    15421 cagggcaacc tctctggcat ggtatctagg gttgctttct tgtttatagg ttgattcatg
    15481 ctcctcatcg ataataattg caccaatccg ctctagtggg gagaaaatag cagagcgggc
    15541 accaaccaca accttagcct gtcctgtttt tatcttgcgc cactcatcaa acttttcacc
    15601 atctgataag cctgaatgca taatagccac ttgctttccg aaacgggaaa taaaacgaga
    15661 ggtcatctga ggagtcaacg aaatttctgg cactaaaaca atggctgtct tatcctgttt
    15721 taaaaccgct tcgatgatat gaagataaac ttctgtctta cccgaacctg taatcccttc
    15781 aatcaaaaaa ggtttactcg gtttcccaat ttgttcaaca atttcagtaa cagctgacgc
    15841 ctgctgttca tttaaggtta aaaaagaaga tggtttgatc tggtcaaaat aggactcact
    15901 gcgatcaatt ggacgttcgt caatacgaat taagtgattt gtcacaaagt aagccaccac
    15961 atctctagaa aaggcttgat aaagcgttgc aagtttagct tccttcgtat gggttagcag
    16021 atagtctttt aataattgac gctttttggc acgactagag atgggatgta ccgctaaggc
    16081 gtctaagtcg acgtgataat atttttctgt ctttaggttt ttcttgtctt tggctaaata
    16141 actaacagta atatgcccag cttgtatgcc cttaagagct attttttcct tctcgcggtc
    16201 taaggtagaa tataagacag atggttttcc ttcaaaaaga aagtccctat cagacttttt
    16261 tagacctgac tctggcctta gcactttatc atagttagag ttaagaagat taggaatcat
    16321 tgcttttaag agcgtgattt tataagaaaa aactgttttt cgaagctgat cagcaagggt
    16381 caattgctct tggtttagga ctggctcagg atctaaaacg gtctgaatca gtttaagaga
    16441 gcttgaatct tcttggccaa aaccaataat aaagccttgc aacaaacgat tcccttttcc
    16501 aaaaggaaca tgcacacgag aaccaagctg cacgagagaa actaactctt ttggaatacc
    16561 ataagaaaat ggcttgtccg tttgcatcaa tggaatatct acaatcacat gagctacttt
    16621 ttccatttgc ttctcctttt ctgtcatgga catcgtacta aatatgaaaa aatctaagat
    16681 ttctgaaacc ttagattttt tctccttctt cttctttttc tttggcaatt tgttctttga
    16741 ttttacgttc ctcttcctct ttggccaagc gttctgcctc aatcttagca cggacagctt
    16801 cacgtttagc tgaaggatct gggtgaatca caacgtttcc tgattcaatt tcttcaagtg
    16861 cctgaagtgt tgacttcact gatttaaatt cttgagttgg agtggcacca gcttctagtt
    16921 catgggcacg tttggcttgt aaaatcacaa gtgaatactt ggatggtact ttatctaata
    16981 aggtatcaat ggaaggtttt aacatcataa tgcttactct tttctattta gctttaaagg
    17041 aattttttgt tattttaatc attttatcat aacgaccaat cacgcgctcc acacgaaagt
    17101 gttctgtctc aatgatacgc ttaacccgct cagctgccaa ggcaacttca tcattaacaa
    17161 ctgcataatc gtattcgcgc ataagggcaa tttcttcttt tgctctttca atacgttgag
    17221 ctatgacttc ttgactatct gtaccacgac caaccaggcg gtcttctaat tcatctaaat
    17281 ctggtggtgt taaaaaaaca aaaacaccat ctggtacttt tgacttaacc tgaagagctc
    17341 cttgaacttc aatttctaaa aagacatcaa ttcccttatc aagagtctca ttaacataag
    17401 ttaaaggggt gccatagtaa ttaccaacat attcagcata ctctagcatt tgaccagttt
    17461 taatgagttc ttcaaattct tcacgtgtgc ggaagaaata atcaacccca tcaacctcgc
    17521 ccggtctttg cggacgagtc gtcattgaaa ccgaatattc aaatttatga tctggcgttg
    17581 aaaaaatttc ttgtcttacc gttccttttc cgacacctga agggccagaa aagacgatta
    17641 acaaaccgcg ttcagacatt gtattctcct tattagttgc tttttaatag tttatcaaaa
    17701 aggctagtct ttttcaagaa cattttcaaa ggcaagtcat aaagaaaaag aggataattc
    17761 ctctttttct acttggcata atcaaccgct ctcatctcac gaataacagt tactttaata
    17821 tttcctgggt aatctagatt gttttcaatt ttttctctta ctttatgcga caaaatgaca
    17881 acctgatcat ctgaaatttt ttcaggttga accataatac gaatctcacg tccagcttgt
    17941 agagcaaaac tattttgtac cccatcaaaa cttgtcgcga tttcttctaa atcacgaaga
    18001 cgcttgatgt aattctccat tgactcatta cgagcgcctg gacgagccga actgagagcg
    18061 tctgctgcag ctactagcac agcgatcaca gaatctggct ccacatctcc gtggtggcta
    18121 gcaatagtgt tgacaacaac tggatgttct ttgtatttac gtgcaaattc cattccaatc
    18181 tcaacgtgac tgccttcaac ctcacggtca atagctttac ccatatcatg caagaaacca
    18241 gcacggcggg caagagcaac attttcacct aactcaccag ctaaaatacc agctaactta
    18301 ccaacctcaa cagagtgacg taggacattt tgaccaaacg aggtacggaa ttgcaggcgt
    18361 cccatgattt taatcaaatc aggatgaagg tttggtgcac caatctcata ggctgcagct
    18421 tcaccgtact cacgaatacg attatccatt tcaagacgat ttttctcaac caattcctcg
    18481 atacgagctg gatggatgcg accatcagca atcagagatt ccaaggtcat acgagcaatt
    18541 tcacgtcgaa taggatcaaa tcctgataag ataacaactt caggagtatc gtcaataata
    18601 acgtcaatgc cagtcaagct ctctaaagta cgaatattac ggccttcacg tccaataatt
    18661 cggcccttca tgttgtcgtc tgggagatgg acactggtaa tagtttgttc agtcacatac
    18721 tcaccagcaa ggcgttgcat ggcttgcgct aacaagtcct tggctgtttt aactgttcgg
    18781 tccttgatgt cacgttcggc atctcgaatg cgcgtcgcaa tttcatgggt cagtttgttt
    18841 tccgtctcca ttaaaatcac ttcacgcgct tctgcaatcg tcatcgcagc aactttttcc
    18901 agttctgctt ttttctcctc ttcaagtttt tccacttgaa gttgccgctc atcaatgtgt
    18961 ttagatttat cggtcagact ttgttcttta ctatctagta ccttttcttt acttgatagg
    19021 ttttcatctt tacggtcaag agttaaggag cgctccgcta agcgtgtctc gagttgttta
    19081 agctcttgtc tttcagactt aaattcttgt tcaatctctt cacgatattt tcttgcctct
    19141 tcttttgctt ctaaaagtaa ttctttacga tttgctttac tttcacgttt agctgttttt
    19201 ttgatgtgtt cagcatctac ttctgctttg ccacgaatat caacagcttc ttgttcagcg
    19261 tttaaaagag tcaactctgc agcttccttc gcagacttga gtctaatcga aataagtgca
    19321 taacctaata ttaaaccaat gagggcagaa acaattaata aaataatatt aaccatgttt
    19381 gtacctcaat atattctaga tttcattaat agaaagccat ctcttagttt atcataaatt
    19441 gagcgtttac acaattccaa ttcattttta aaaaaattaa catttgggcc aagtggttga
    19501 gaaccctact taaaaaaaga ctgtagcaag tcgtccatga tgtaggcttc tatttcagaa
    19561 taactttttt ccggaggcgt gttaagacaa cacgccaaga aatgggacgt tccattggaa
    19621 tacacttaat gtcctttaat tggtataatt ctgtaatagg tttgggacaa atagttaaga
    19681 cgttgtgatt aatcttggta gaattaagca taaaatccca ggaagaggac gtcaaaataa
    19741 tattaggtct gacttggtga cgctcgcaag cttcaagcac taaatggtga accgtgaaac
    19801 taggatcaaa tagggcaagt tgttcatctg ttaaatcttc ccactgaata acttttttgg
    19861 aagctaaacg atggcgtgga gacaggcata cagataattc tgatctctgg atttcataag
    19921 tctcaaccaa attatcagcg atgcctgttg gggataacaa gactgcgacg tcaacatttc
    19981 ccacgagtag ttcatttttt agttggtaag caccaatctc cttaacattg aattgaatcc
    20041 ccggattttc taaaatcagt tttggcatta cttctgagaa aacaactgat aaaataagag
    20101 gaggaatacc aatattgata cttcccttta accctttact gtgatcatgc aatttcaaaa
    20161 acatgtcatc atagagactg agaacctttt gagcgtcctt ataataatta tcaccaagat
    20221 aggttaaccc aataatacga cctctttttc gtttgaagag cttaacattt tctctttttt
    20281 caaaatcatt gatcatcatg ctaagtgtcg gctgcgacac atacaacagt tccgccgcct
    20341 ggctcaagtt aaaatgattt tcaacgattg cgataaaata acgaatttgt ttaatatcca
    20401 aataggattc tccttgtctt atcaattgct ttttccggta taattaccta tattatgaca
    20461 caagtagatg ttaaatgcta ttgccaactc tatcaaaaaa atttatatgc ttataaaaat
    20521 tctatatttt tatttttagc gttttcttgt tatcttagag acatggaaag cgcttttcta
    20581 aaactgaaag gatgtttatt ttatgaaaaa catagttatc gttgaagctt tacgaactcc
    20641 tatcggagct tttggaggct cctttaaaag tgtctctgct gttgaacttg gaacaactgt
    20701 actgaaaaaa atccttgata aaacgcaagt aaagcctgaa atggttgatg aagtcatcct
    20761 aggaaacgtc cttcatgcag gcctaggaca aaatgtggca agacaagttg cagtccactc
    20821 aggaattcct gaagataaaa cagctttcac attagatatg gtttgcggtt ctggacttaa
    20881 agcaatccaa ttagctgcgc aaagcatcat gcttggtgac gctgatatcg ttattgctgg
    20941 tggtgtcgaa aacatgtcac aagcaaccta tgtatcaact cagcaccgtt ttggacagcg
    21001 acttggtaat agtcaattga ttgatactct tgttcatgat ggcttaacag atgcttttaa
    21061 caattaccac atgggtatta ctgctgaaaa cgttgctcag aaatatggca tctcaagaga
    21121 agagcaagat caatttgctt tagaaagcca agaaaaagct gctaaagcat tagaaaatca
    21181 tcgttttgct gacgaaattg tccctgtctc tgtgcctcaa cgacgcaaag accctttaat
    21241 tgttacaaca gatgaatacc caaaagttga tacaagcctt gaaaaattac agcaattacg
    21301 tcctgctttc ctccctaaag aaggaaccgt tactgctggg aatgcctcag gaataaacga
    21361 tggtgcagcc ttattgatgt taatgactga agaaaaagct cttgaattag ggttaacacc
    21421 tttagtcact attgaaagct atgctagtgc aggtgttgca cctgaactga tgggaactgg
    21481 accaattcct gccactcaaa aagcccttaa gaaagctgga ttaacaattt ctgatttgga
    21541 cttagtggag tccaatgaag catttgcagc acagtccttg gcggttttaa aagatttaaa
    21601 gttaaaccca gaaatcgtga atgttaatgg aggagccatc gctttaggtc atcctattgg
    21661 tgccagtggc gctcgcattc tagtcacatt aatccacgaa atgaaaaaac gccaagtaac
    21721 cagaggacta gcaacacttt gcattggtgg aggacaagga actgctgtta tcgtgaaaaa
    21781 caatacttag tctcgtgaaa gttggtagaa aaaatgtgta aagaaatcac aataaaagaa
    21841 gcggtagctc acgttaaaga tggtgatacc attatggttg gtggcttcat gacaaatggc
    21901 acaccagaaa aattaattga tgcacttgtg gaaaaaggtg tcaaagacct cactttaatc
    21961 tgtaacgatg ccggttttcc tgacaaaggc gttggtaaga tggttgccaa taaacagttt
    22021 tcaactatta ttgcatcaca tatcggtctc aaccgtgaag caggccgaca aatgactgag
    22081 ggcgagactg taattgatct tgtacctcag ggaacattag ctgagcgcat ccgcagtggc
    22141 ggttttgggc taggcggttt cttaacacct actggaatag gaaccgaagt tgccaaagga
    22201 aaagaagtca ttactattga cggcaaagac taccttcttg aaaaaccttt gaaagctgat
    22261 gtcgcactta tttttgctaa caaggcagat aaaaatggca atttgcaata cgcaggttct
    22321 gaaaataact ttaatcatgt gatggctgct aatgcgaaaa ccaccattgt tgaagcaaga
    22381 gaaattgttg acgtggggca aatggatcct aattttgtcc atactcctgg catttttgtt
    22441 aactacttag tgaaaggagc ctaacatggg aacatcaact actgttcttt caaaagaaga
    22501 gattcaaaca cgtattgcta agcgcgttgc acaagaatta gaacacaata cactggtcaa
    22561 cttaggcata ggtttgccaa caaaagtagc caactatatt cctgaaggtg taaccattac
    22621 cctgcagtcc gaaaatggtt ttgtcggtct cactggatta acagatgatc actacgatcc
    22681 tactattgtt aatgctggtg ggcaacctgt tagtattgct cctggagggg ctttcttcga
    22741 tagctcaact tcctttggta ttattcgagg cggccatgtg gccgcaaccg tcttaggtgc
    22801 cttacaagtt gataaagaag ctagcattgc taattacctg attcctggaa aaatggttcc
    22861 tgggatggga ggggccatgg acttattggt aggtgctaaa aaagtcattg ttgcaatgga
    22921 gcataccaat aaaggcaaag caaaaatttt agacaaatgc acccttcctc tgactgctca
    22981 aaatgttgtt aacctaatca ttactgaaat gggagtcttt gaatatcaag atgaaggtct
    23041 atgcgccctt gaaattaacc cagattacac ctttgaagac gtgcaaaacg ttaccgaagt
    23101 taccctaatt gataaaacaa actaaagact aaccaaaaga aagacgagga tagtatcatg
    23161 acacatacta aagaagttgc atttatcact ggtgctgcaa gcggaattgg aaaacaaatc
    23221 ggggaaacct tattaaaaga aggtaaaacg gttgtttttt ccgacattaa tcaagaaaaa
    23281 ctggatcagg ttgttgctga ctatactaaa gaaggctatg acgcttttag tgttgtgtgc
    23341 gatgtcacca aagaagaagc catcaatgct gctattgata cggttgttga aaaatatggt
    23401 cgtattgata ttttggttaa caacgcaggt cttcaacatg ttgccatgat tgaagatttt
    23461 ccaactgaaa aatttgaatt catgattaaa atcatgttga cagcaccatt tattgccatt
    23521 aaacgtgctt ttcctacaat gaaagctcaa aaacacggtc gtattattaa tatggcttct
    23581 atcaatggtg tcattggttt tgctggcaaa tccgcctaca attcagctaa gcacggcttg
    23641 atcggtctga ccaaagtaac tgccttagaa gctgctgatt caggcattac ggtcaatgcc
    23701 atttgtcctg gatatgttga cacaccactg gttcgtggcc agtttgaaga cctttccaaa
    23761 acaagaggta ttccccttga aaatgttctt gaagaagtgc tatacccact tgttcctcaa
    23821 aaacgcctca ttgacgttca agaaattgca gactatgtgt ctttccttgc cagtgataag
    23881 gcaaaaggtg ttacaggtca agcctgtatc ttagacggtg gctacactgc tcaataaatt
    23941 tggagagata aagaggctgt atcttgtgat ctgtctcttt attttctaat aaggaggtca
    24001 taaaactatg gaaattattg gttctctggg ggtcttggta ggtgttattg ttattattta
    24061 cctgtatgtc aaagaagtta acattatcat cgctgcgcct cttgctacca gcttggtcat
    24121 tttgtttaat caaatggatc caaccacaac cttacttgga aaagaaccca accaatttat
    24181 gggggcactc tccacttata ttctcaatta ttttgctatc tttttattag gttctatctt
    24241 agccaaatta atggaaacaa gcggtgcaac cacttctatt gcagattata ttttaaaaaa
    24301 agttggtcat gatagtcctt ataaagtact cgttgctatt tttctgatca gtgctatatt
    24361 aacttatggg ggaatcagcc tctttgttgt catgtttgct gtcttgccgc ttgcacgaag
    24421 cctattcaaa aaaatggact tggcttggaa cttaattcaa gttcctcttt ggctcggtat
    24481 tgcaactttt accatgacga ttttacccgg aacacctgcc attcaaaatg ttattcctat
    24541 tcaatacttg gacacctcac taactgctgc cgccattccg agtatcgttg gctcaattgg
    24601 ctgcgtggct tttgggctct tttatatgaa atattgtcta gcaaaaagta tggcaagggg
    24661 tgaaacttat gccacttatg cttttgacaa tgagatacaa gtgaaaacaa aaaatctccc
    24721 acatttcctt gccagtatct tacctttatt gttgctcatt attatcgccc taaccggtag
    24781 ccttttcgga aacgattttt ttaagaagaa cattattttc atagcacttt tagctgtcat
    24841 tctcaccgca agctggctct ttagacagtt tattcctaat aagattgctg tctttaattt
    24901 aggagctagc agctctattg cacctatttt tgcgacagca tctgcagttg ccttcggagc
    24961 cgttgtgatg attgtcccag gtttcacatt cttctcagat ctcattttga atattcccgg
    25021 taatcctctt attagtttag ccgtgttgac ttcctctatg tcagctatta ccggctcttc
    25081 ttccggtgct ctaggaattg tcatgcctaa ctttgcccag tattatttag atcaaggcct
    25141 taatcccgaa atgattcacc gtgttgccac tattgcttct aatatcttta ccattgtgcc
    25201 ccaaagtggt gtctttctca ccttcttagc attgacagga cttaaccaca aaaatgcttt
    25261 taaagaaacc tttattactg tttctgtaag tacttttatc gcacaggtca ttgtgatagc
    25321 ctttgatctg ttttcttagc cttttctcct ccacaagtag ccactttctc actatttgtg
    25381 ttatgataaa gtgtaaaaca aaggagattg aaatgacaaa agaagttatc gtcgaaagtt
    25441 ttgagctaga tcatactatt gtaaaggccc cttatgttcg tcttatttct gaagaatttg
    25501 gacccaaggg cgatcgtatt acaaattttg atgttcgcct agtgcagcct aaccaaaatt
    25561 ctattgaaac agccggtttg cataccattg aacacttact tgccaagctc atccgccaac
    25621 gcattgatgg gatgattgat tgctctcctt ttggctgtcg aacaggtttt caccttatca
    25681 tgtggggaaa acacagttct actgatattg ccaaggtgat taaatccagc ctagaagaaa
    25741 ttgcaactgg gattacttgg gaagatgttc ctggaacaac tcttgaatcc tgtgggaact
    25801 ataaggatca tagcctcttt gccgccaaag aatgggctca attgattatt gatcaaggga
    25861 tttcagacga tccttttagt cgccatgtca tctgatacta gtgtgttgtc aaacataaca
    25921 atcctactga cctatttgac ttgttacaaa aaacaagtct atctgcagat tttaagacaa
    25981 catactttat taatcaaaaa actgagacaa gttgccttat ctcagttttt ttgattttct
    26041 cagtaatcta aagcatcagc ataacctttg ccatttccta caaaataacc cgtcttacaa
    26101 ttaatagaga acagataagt gccatcaggc ttaaacatat tatagtaacc attgccatta
    26161 ataatattaa ccggctctaa aatatattgg ttgcctgaaa tataacctct agcttgtgag
    26221 gttgctacaa ttttttcaag aactcctgga ttaaatgccc aagatgggtt agctctgtca
    26281 gcaataacat cttgattgta aggtacacgt gataaatgcc gttgtaagct tgcaggatca
    26341 taacttgtca agccatagcc agatggtgct actgatgtac tttgtccttg agctgcttga
    26401 tcctggactg cttgctcatt agctgcttta gcggcctcag ccttgctggc tagttgctga
    26461 cgaccttctg tgatgcttgc ctgcaagaca gcatcaagat ttgcatttcc tgttgtcaag
    26521 gttgcacttg ataaatcatc aaaattagca tcagccttga cttcagccga aaccttttca
    26581 ccatctacaa caacatcgga aacaaattta ccgttaaccg ctgtaatagc agcaatagct
    26641 ttcttaaggg aatcgacttt tgctttcgcc ttatcatagt aagcagagcc ttccaaagct
    26701 ttcaaggcag cttctaaatc tggcaaagta gcaaaggcac tattttttaa tttgctcttt
    26761 gtggcatctg tataaaaagt accatatagt ttttcgaaag ctttagcagc agccttcaag
    26821 cgcgttgctt ttttagcact gtcggtctgc aaagaggtct ttgtctgttt acttgctgtt
    26881 tgagttgttt taccactgtc ttgtctcaag aaatggttcc aaccaaatac aactgcaaga
    26941 atggccaata atagcagaaa taaagctatt aaccaacctt ttttcgtgtt ttgtttggct
    27001 ggatggtggc tatcttcaga aagaaactga tctctttttg gttcttcctt ggtcatctgt
    27061 ggttctggaa tgaccctctc tgatggatct agatctaaca cagggactgt cgcttccacc
    27121 ggaatcccag ttaccaccgc agtagtctcc attggagcta agtcttcagc tacttcttca
    27181 accaaagtgc tatcttgctc agcagactcc gcagacacag gttcgtcatc aacaagaccg
    27241 gctttactca atgcttctct ttgttttttg ataaagttat ctaaactagc tgtatcaagc
    27301 tctgtatact tagcatcaaa cttttgagaa gaaacttcgt cacggtgttg cttaatgtac
    27361 ttatctaaaa tactatcatc cttagtaaca cctgctttta tctctgactg tttgcgtaca
    27421 gcttcaccaa ttgtcattga cttggcttca ttaagcccca atgtttgcga ttcttttgtt
    27481 acttcgactt ctttgctttc ttctgacacg cttactacct ctctatatca gatgtcgctt
    27541 taccctttcc ccataaaatt ggtacaaatc aacttttagg gtgccgttat aaagtttacg
    27601 ttttttatca gctttttgcc cgtattttag ttcaaaaagt tcatcacttg taaggataaa
    27661 tttgctccat gttttcaatg gtgcaaaggt ttgtcccatt tcattataca agatgtcaac
    27721 cgctttgtca tcaagcaacc gttctccata aggaggattt gatatcacta caccattaac
    27781 cttgtctgtt cgaaagtctt gcagacgcat ttgcttaaag gtaatcacat cagataaacc
    27841 agcttcttca gcattacttt tagcaatctc aatcatgcgg ccatcgatat caaagccaga
    27901 aatatctaat tcgatttcat aattagcttc ttgttcagca tcatcacgaa cttgttgcac
    27961 catatcttta tctacccagc tccattcttc aaaagcaaac gaacggttaa atcctggagc
    28021 aatattcatc ccaatcatgg ctgcctcgat gcaaaacgtt cccgatccac aggtgggatc
    28081 aaccagaggt ttatctggaa accagttaga taaggccaag atagcagctg ccatattttc
    28141 cttgatcggt gctccacctt tttgaacgcg ataccctcgt ttaaataggc tagatcctgt
    28201 cgtgtcaatc ataatagtgg cttggtcttt taaaatagat acctcaatgt taaacgttga
    28261 cccaacttct tgaagaggaa ctccttctgg cctgtggaaa tgcttttgca gtttcttaac
    28321 aacggccttt ttggtaatcg cctgaacact tggctcgtta tgcaatttag acttaacaca
    28381 tttggctttt gagattggaa atttagctcc tagcggtaaa taattttccc aatccaaggc
    28441 aaagacacct tggaataatt cttcaaaggt tctagcagga aattgtccta cgataatttt
    28501 gatacgatct gctgcacgta accaaagatt tgttttaaca atcgcttcta catcaccttc
    28561 aaaataaact ttcccatttt caacctgaca atcaaagcct agtgctctga cttctttacc
    28621 aacgacagct tctaaacctg cggctgcagt tgcgactaat ctaaatgttt ctttcatata
    28681 tctctttctt ttaaatcaaa taaaagctag caaatgctag cttaacctat tatgcaattt
    28741 tctataagcc atgttttgtt ccggaaataa ctaggaatta tttccttcga taatcatctg
    28801 tctaccgtct gttgacagtc aggatagctt gttcgtttcc aactatccca tgcccctacc
    28861 aaagtttggg ttgctagctt gaggggttta ccgcgttcca ttttttacgt ttccataaaa
    28921 actacgtcac tgtggcactt tcagaagtac tttggcatat caaacgactt agccatttcc
    28981 ttcgccgtaa tgtgtatgca catccctagg cttatgtgtt cgcctagcac aatcactact
    29041 ggcatcacag ccagtgctag catggacttt cctcatagta ttaaaatact acgcgattat
    29101 ccaaaaattg cacagttttc attactcaat aatttgttta ccaaaaacct ctttttccaa
    29161 tttactaata cgtttcaaga tgtcaaaatt agtagctgat tgagcaacac gagtcggttg
    29221 cggtactggt tgttgaacag tcgctgaaac tgtatttcta gcttgaaact tcgccttttt
    29281 taaggcttca ttctcagctt ttaaagcttc aatttgagca ttgaaatttt cataatcttt
    29341 aattacatta tcaagaaatt catcaacttc tttcttatca aaccctcgca tactagtctt
    29401 aaattcttgc tcaaaaatat ctttaggact ataaataata cttgtcattc tttactctcc
    29461 gaacggtcaa tctttttacc aaaattatat ttcagtatta ttatcaatga tacagaaaaa
    29521 tagttcaaaa agcaagtatt taaataccaa tacccctaaa aatacaatgc tagctttgtg
    29581 acatatcatt tagccgatca aaggttagca atagcaactg ataatgcggc atatcttttg
    29641 ctttcttgag aaaatatttt aagttggtct cgttttctgt gtcataaaaa acataagccc
    29701 cttctgtctt ttctaataaa aactgataat attgactaaa ttgcgtcggt tgttcgtaat
    29761 ttggaaagta atattttaca aagtcaacag ccctaaactg acttaaaact tctttatttt
    29821 tttcattcca cctatctcca tgcgtttcaa acaagaatat agtagctatc tgcaagggat
    29881 actcctcttt tagctcatta gctacttcca aagcccattg ttcaaaaccc aagttccctg
    29941 taaagataaa ccaatccaca ccattttcca aataacctat taaatcttta cgaatagcct
    30001 gtttaataat tgaaactcgt gggtctttat ggtcaaaaat ccctatttca aagcttcggt
    30061 aacctgtaat tagaatcgca gtcattaggt gttatccttt caaaaaatat gttataataa
    30121 aagtgcttaa atttttagca ttaactagat aatattagga gaacaatggt taattatcct
    30181 cataatctta ttcgacaaaa agtaagttcc gttcaaaagc aaaataaggt ggacttcgcc
    30241 aatagaggta tgtcctttga agctgctatc aacgcgacaa atgattatta tttatctcgt
    30301 caaatagctg tcattcacaa aaaacctact cctgtccaaa ttgtcaaagt ggattaccct
    30361 aaacgcagtc gggcaaaaat cgttgaagcg tactttagac aagcttcaac gactgactat
    30421 tgcggcgttt ataaaggaca ttatgttgat tttgaagcaa aagaaaccag gcaaaaaaca
    30481 gctatgccca tgaaaaattt ccatttacat cagattgaac atatggcttg cgttttacat
    30541 caaaaaggaa tctgctttgt ccttcttcac ttttccacac tgaaggagac ttactaccta
    30601 cctgctcaag ccttgatttc attttatcag atagataatg gcagtaaatc gatgcccatt
    30661 gattatatca gaaaaaatgg ctttaaggta gcatttggag cctttccaca agtcccttat
    30721 ttaaacataa ttgaacaaaa ttttttaggc ggtgattaca attaaaaatc caaaaatcct
    30781 taagtggcta aagtatgtat taagtgcaat tcttagcctt attatccttg ttattattat
    30841 tggtggtctt ttgtttacct tctacattag cagtgctccg aaactgtcag aagcccagtt
    30901 aaaatcaaca aactctagct tggtttatga cggtaataac aatctgattg ctgatttggg
    30961 ttctgaaaag cgtgaaaatg taacagctga tagtatccct attaatctag ttaatgctat
    31021 tacctcaatt gaagataaac gtttctttaa ccatcgtgga gtagatcttt atcgtatttt
    31081 tggtgctgcc tttcataatc taacgagtca gaccactcaa ggggggtcaa cgcttgatca
    31141 gcaactcatt aaactagcct atttttctac taatgaatct gatcaaacct taaaacgtaa
    31201 ggctcaagaa gtttggcttg ctcttcaaat ggagcgaaaa tatactaaac aagaaatcct
    31261 gactttttac atcaacaaag tatatatggg taatggcaac tatggtatgc tgacagccgc
    31321 taagtcttat tatggcaagg atcttaagga tttatcttat gcccaactag ccctattggc
    31381 tggaatccct caagctccta gtcaatatga tccttacctt catcctgaag ctgctcaaaa
    31441 tcgccgtaac gtcgtgttgc aacagatgta catggaaaaa catctgacga aagcagaata
    31501 tgaaactgcc atcgcaactc ccgtcgctga aggtctacaa tcactccaac agcgctcaac
    31561 ttatccaaaa tatatggata attatctaaa acaagttatt gaagaagtca aaaaagaaac
    31621 gaataaagat atttttaccg ctggtttaaa agtttatacc aatattatcc ccgatgcgca
    31681 gcagactctt tataatattt atcattctgg tgattatgtt tactatccag accaagattt
    31741 ccaagttgct tcaacgattg ttgatgtgac aaatggtcat gttattgctc agcttggcgg
    31801 acgtaatcaa gatgaaaatg tttcatttgg gactaaccaa gctgttttaa ctgatcgtga
    31861 ctggggttct accatgaagc caatcacagc ctatgctcct gctattgaat ctggtgttta
    31921 tacttctact gctcagtcga ctaatgactc agtctattat tggcctggaa ccactaccca
    31981 attgtttaac tgggacctta gatataacgg atggatgaca atccaagctg ctattatgct
    32041 atcgcgaaat gtcccagcag tccgagcact ggaagccgca ggacttgact atgctcgatc
    32101 tttcttaagc agtttaggta ttaactatcc cgaaatgcac tactcaaacg ctatctcaag
    32161 taataacagt agctcagata aaaaatatgg tgcaagtagt gaaaaaatgg ccgctgcata
    32221 cgctgctttt gcaaatggtg gtatttatca taaaccaagg tatgtcaata aagtggaatt
    32281 tagtgatggt acaagtaaaa cttttgatga aaaaggaaaa cgtgccatga aagaaaccac
    32341 ggcctatatg atgacagata tgttaaaaac tgttctcact tatggtacag gtactgctgc
    32401 tgccattcct ggtgttgcgc aagctggtaa aacagggact tctaactaca ctgatgagga
    32461 actagctaaa attggtgaaa aatacggcct ttatccagat tatgttggta cattagcgcc
    32521 agacgaaaac tttgttggct ttactaagcg ctacgccatg gctgtttgga caggttacaa
    32581 aaaccgcttg accccagtat acggatcaag tctagagatt gcatctgacg tttatcgtag
    32641 catgatgact tacttaacaa atggttacag tgaagattgg acgatgccaa atggtcttta
    32701 tcgcagtggt ggattcctct acttaagcgg aacctatgcg agcaacaccg actatactaa
    32761 ttcggtttac aacaatcttt acagcaataa cacgacaaca gcttctagcc aaacgacttc
    32821 agatgatact agtagtagca atgatacaag taattcaacc aatacagaca acaatggcag
    32881 tcatccatct accgatgata aaaagacaac tcattaatct ctaacctcta cttattgtct
    32941 gtacctacct tttattacat atccatttag ttacttttaa tatctacctt aagtgataat
    33001 ctaaataaaa agcgagtcca cgttctgtga ggactcgctt tttatatgac acaaatgact
    33061 taccacatac aatataaaac aaaaaacaga attctttaat cgtattaaag aaaaggtaca
    33121 acgttaaggg aattagcaac tgatttttca aacgttaacc taaaacaaaa tagacttatt
    33181 taaaattgtt ataaatagca actaatgcca taagagagta tacatgaaaa aaacacgttt
    33241 ccatataccg aagacgtgtt ttttcatatg tcattttctt agcataataa tttttttcat
    33301 gttcactttc ttatgcggag tccaatccgt ttgctgttcg ttttgtccag cttttagatt
    33361 tcatacagtc gcaaagaaag gaattagtat tgtgctaaag cacccattgg atcccaagga
    33421 gctagtactt gtggctcttt ttcataagcc gctaactcgt cagctgttaa gaattcttta
    33481 cggacaacaa tttgataggt atattcatcc atccaagcat ctgaagcaac aaagtaacct
    33541 ttgtcaccaa ccttctcacc ccatgaattt tcaaccttcc attttaacgg ttttcctgtt
    33601 tcatctaagt caacacctgt taaaaccata gcatgtgtca tcaaactttc actataatcc
    33661 aaacgtccag ccttatcttg actaagattg atatccatac tagcttcaaa atcgtaagta
    33721 ttagttgcta aaatgccttt ttgacgatct gaaacttgac ccacatcaga gccaaaccaa
    33781 acggactcac cagcctgcat ctgcttgata gctagttctt tgaaacgttt catatcaagg
    33841 ttgaggtagc gaacctcacg actaccgacc acatttccta gcatctcaac agtgtatgat
    33901 ttgccataag gcttatcagc agttggcgca ttaataacag acacataatc agaaagcttt
    33961 aagccaacaa atttgtcgta aaacgcttgc ggtgtcaaac ctttctcaac atgatagtgg
    34021 tcatctttat cacggtaggc aaaatcaaaa tgacgaggtg gtaaaccaag ggtcatggcc
    34081 aagaagttaa aaatttcctg aagaagctct gcttttcgat cctcaacttg gtctgcctta
    34141 gcacctgacg caatcaggtc acgaagaatt tgagcatctt ggcgcaataa tttattcaaa
    34201 tactggttta attcacgact gttacttgat gagattgatt ctgggtaaac agattttggc
    34261 accactccat acttctcaaa caaggaaacc accatgtccc actgaccacc atcttgttgt
    34321 ggaacatcca agagaaactt aactttacga ctggttaatt cttggtcagc tgtagcaatg
    34381 acctgctcca taaaccagtt agctttttca tacttatccc aaaagaaagt atgagcttgt
    34441 gacagttcaa aattttctaa cttaaattct gtgattaatt tgtgtcggaa agtgttcaag
    34501 gcagcaaaca tccagcaacg accagaagcc ttttggttag ataccttatc tttagttaaa
    34561 tcaatagaaa acacaaaatc attgtccact tcactttgac gggtttctaa tgattttagc
    34621 aaaccattat gcgtaacggc attctcaata gctgaaaatt ttgcattggc ttcgtaatga
    34681 gcaaataatt gttctgtaaa tgtctctgtt aatgctgaca ttattgtcct cctaaaatat
    34741 taagataagc ttcacctgaa ataatattgg caagatggtt attatccagc cattctattc
    34801 taaaggatta cttctattat agaccttatt tgattttctt caagaaaaaa gttaggataa
    34861 cctaactttt tttgttttct ttttttactc tttgaacatc atctcttatt tccaaaaatc
    34921 atcaaaaatg gtgattggca ggtgacgctt gtgttgtcct ttatgccacc atttttcaat
    34981 agttgcttga gctactttgg aaatcagctt cccttccaaa tagtcgtcga tgtcttgata
    35041 ggtcacccct agagcaacct catcagccaa gcctggtttt tgatcttcta aatcagcagt
    35101 tggaactttt tcatacaaag cagcatctgc tcctaaaact ttcaaaagag cctttccttg
    35161 acgtttgtta agcctaaaga ggggaagaat atctgctcca ccatcaccaa atttagtaaa
    35221 gaaaccagtg atgttttctg ccgcatgatc cgttccaata acagcaccag ccatttggcc
    35281 agcaatggca tattgactga tcattcgctg acgtgcttta atattacctt tattgaaatc
    35341 agaaatctca acgcctgctg cttgtagagc ctctacttga ccgtccacag ctgccttgat
    35401 attaatggta agggtctgat ctggtgcaat aaaagccaag gctttttgcg catctgcttc
    35461 atcagcctga accccataag gcaagcgaac agctataaat tggtaagctt gatcacttgc
    35521 ttcctcccgt aactctgcaa tggccatttg ggctagcttt cctgcgaggg tagaatcctg
    35581 acctcccgaa atgcctaaga cataagtttt taaaaatgag tgcttacgca aataagcttt
    35641 taaaaaatca acggctttcc gaatttcttc ttgtgggtca atgctagcct tgacgcctaa
    35701 ttgtcgaatt atctcttctt gtagtgtcat gtcattcact ctttccataa gcatctttgc
    35761 gaatgttatc aattaaggcc atcttgtttt gccacacatc acgggctaag tctactgggt
    35821 agtcttgagg atttaagaca cgcttgtatt catcccaaag cttgtcaaat tcttttttag
    35881 cataagcctt gatttcagct aaggtcggta gctggtaaac taattctccc ttgacaaaaa
    35941 tatcaactaa gagaggaatt gcatcaaatt ctttaacggt tttcttaata taggtatagg
    36001 tcggatggaa catctcaatc tcagttaatt cattaacatt aatatcagta aacgtgatat
    36061 agtcgccttc tgatttgcct ttttcacgac tggtgatgcg ccaaacttgt tttttacctg
    36121 gtgtggatac tttttctgca ttatttgata atttgatcgt atcacgcatg ctgccatctt
    36181 cttgctcaat agagacaatc ttataaacag cacctaaggc aggctgatca taggctgtga
    36241 tcagtttggt cccaacaccc caaacatcaa ttttggcctt ttgcattttt aagttgagga
    36301 tggtattttc atcgaggtca ttagaagcat agatcttagc ctcggtaaaa ccagcgtcgt
    36361 ctaactgctg acggactgtt tttgagaggt aagccaagtc accagagtcc aatcgaacac
    36421 ctagaaaatt aatcttgtca cccatttctt tggctactcg gatagctgtt ggcacaccta
    36481 ctttaagtgt atcataggtg tcaacaagaa atacacaatc tttatgggtc ttagcataag
    36541 ccatgaaagc atcataatca ttaccatagg cttgcactaa agcatgagca tgcgtacctg
    36601 aaacagggat atcaaagcgt ttacctgctc tcacattact tgttgcatct gctccaccaa
    36661 tcatcgctgc gcgggttccc caaatcgcag catctagttc ctgtgcacga cgggtgccaa
    36721 attccaaaag gggttcatcc tcaatcacag aacgaatacg agcagccttt gtagcaatca
    36781 aggtctggaa gttaacaatg tttaaaagag ctgtttcgac caactgacac tgacctagag
    36841 ggccttctac ttgcacaatc ggctcattag caaaaaccaa atctccttct ttagctgaac
    36901 ggatggtcaa ttctaatcgt aactctttaa ggtaggtcaa aaagttttct ggataaccca
    36961 gttcttcaag gtaagccaaa tctgtttctg aaaattgaaa ttgctctagg tactccacca
    37021 tgcgctgtaa accggcaaaa acagcataac cattgttaaa aggttccttg cggaaataga
    37081 cttcaaacac cgcatgacga ttatgaatgc cctgctcaaa ataaacttgc atcatattaa
    37141 tctgatacaa atcagtatgg agagttaaac tatcatcttt atacataaag gggactcctt
    37201 tgaattattg ttactattat aacatatttt aaaaaagact ctttggctag ggtttagaaa
    37261 taacttgagt tatcgctaaa gtaaaaaaag aactgatcca tcatgacatc ctcaaataag
    37321 aaagagttaa tggattcagt tctatatcgc taattattat ttaaatttga cattgctata
    37381 aatcccaaaa acaataatcc aaatcgttgc tccaatggcg ccgatatagg tggattcttg
    37441 taagaaaaga gagataaaga caaaggcaaa gaaagcaagg gtcaaaggcg ttgtcacttt
    37501 atattttggc atcaaataac catctgccat aaagtcctta gattgacggt acttccagtg
    37561 agcaatcatg gttaaggcgt agatagcaat atatacacct gatgaggagg ccgtaatgag
    37621 tgagaacgca tctgcaactc ctggtaggat attaatcaaa gctgagatac caaccacaac
    37681 cgctgaagca ataatggcac gacttggcac cccttgtcga gataaagtat taatctttaa
    37741 gcgattggtc aaagcgtttg gagtctcatt agcaatctga tagagatgac gaccggttga
    37801 ataaagggtt gagttaagcg ctgacgctgc tgatgtcaag accacaaagt taatcaaggc
    37861 tgctgcccat ttaataccaa tcaatttgaa caccatcaca aaaggagatt catcaactgg
    37921 taactgatgc catggcacaa ttgccataat agagaccaag gctcccacat aaaagatcac
    37981 aatacgggtt ggaatttctt gaatagcctt tggtagaact tttcttgggt tagccgtctc
    38041 agaagtggta attcccacaa attcgatagc ttgataagca aagaaaacca tttggaaggc
    38101 cataaagaac tttagtttcc catttgggaa catggaaaaa tggtcaaaaa tattggaaag
    38161 gctagcatgg cctgtgtgag tttcaaaacc tgtcaatacc atgaaaatag ctgttgcaat
    38221 caaagctaaa atagctaaaa tcttaatcat ggcaaaccaa aactctgttt ccccaaaaac
    38281 gcgcacagca attaagttga tcgaactaag taagactaag aaaaccaact gaatcaacca
    38341 ggctggccag cttgggaacc aaaattgcac ataagcacct actgctgtga tttctgccat
    38401 tccaataaaa ataagggaaa tccaatagga tagacccgaa aaataacccc agcctggacc
    38461 aatgtatttg gaaataaaat tgataaaggt gtgttgatct ggatcataat agagcatttc
    38521 accgatggca cgcatcatca taaacatgaa ggcacctgta atcatataca caaaaataat
    38581 agatggtcct gttagggcaa tagagcgtcc tgcccctaaa aagagacctg ttccaatcgt
    38641 tcctgcgatc gcaattaact gcacatgacg attttctaag ccccttacca ttccattttc
    38701 tagttcgtta ttgtctgttt gttcttttat agacattcta aactccattc actaaaatac
    38761 tatttattat atcctttttt cagaaaattt tcaacattta tctaggaaag atattaagga
    38821 aaactgttct ttatatttct taaaggtctt atgcaattta gcttttttaa gggtgagaca
    38881 aggaaaaatg aaggagtttt aaccttatga agagaaactt tcaaggtagt gataaacacc
    38941 ttgccctgca attgcaccat ctccaacagc tgtcgtgatt tggcgaaggt ctttttgacg
    39001 aacatctcca atcgcaaaaa taccaggaat acttgtcctc atatgatcat ctgtgataat
    39061 ccaaccttct gaatcggtaa tttctagatc ctttaccata cctgtaacag gattcatacc
    39121 aacatagata aacacacctc caaaagcgtg gtcagtgact tggcctgttt tcacattttc
    39181 gattaggaca ttggagacct taatgtcgtt accttgaatt tctttgacaa ctgaatccca
    39241 gataaagtca actttgtcat tagcgaaggc acggtcctgc aagattttct gagctcttag
    39301 ttgatcacgg cgatgaacaa cggttacctt tttagcaaac tgagtaagat aaatagcttc
    39361 ttcaactgct gagtcaccac caccaacgac caaaagatcc tggtcacgga aaaacgcacc
    39421 atcacatact gcacaataag aaactcctcg actagtatag tattcttcac ctggaacacc
    39481 tagtacacgg tatttagctc ccgttgcaat aataaccgtt ttagcttcat aactagcatc
    39541 ttcagtcaac acacacttat agtcaccaaa attttctatt ttttgaacaa taccataaat
    39601 gttttcaacg ttaaacttct ctaaaggttc gtacattttc atagctaatt ctggtccaga
    39661 tatatgatca tatcccgggt aattctctat atcaaaagtg ttgttcatct gaccaccagg
    39721 tgccccttgt tcaataatgg caacagataa attacttcta gcagcgtata aagcggcagt
    39781 cattcctgct ggtcctgaac caataattaa tgtatcgtac atgatttttc tcctttaatc
    39841 tactcttgcc aatattttag caatgataat cccttcttgc aatgattagg attttatgac
    39901 aaccaaaata ctcataaaag caaacgataa aattgggatg gttaaaatag caaccattag
    39961 catctcataa agaaaagctt gtctttcaat caatgtttta tctcttttgg tttttgctcg
    40021 ccataaagtc catattaaac aaattaaaat catagtaagg cttgagagaa tgagaccttt
    40081 tacataaagg ctaaagattt ctactaacat atttccacct agtcattatt tctttcccat
    40141 aagtttttct aaaaaacata acaagaaaag cccagggata cctagacctt tttattataa
    40201 caaaagaata acattaaatg tatgtttttg aatagcttgc aaaaaattct ttggttcgtt
    40261 ctttttgagg atgtctaaag acttcttcag gtgttccttg ttccaagatt ttcccttgat
    40321 ctaaaaagag tactctatct gccacttggt aaacaaaatt catgtcgtga ctcactaaaa
    40381 ccatggtctg tccggattta gcagcatcag taatagactt ttccacttcg ccaactaatt
    40441 ccgggtcaag agccgaggtc ggctcatcta gtaataaaac atctggtttc atagccagag
    40501 ctcttgctaa agctacccgt tgtttttgtc cccctgataa atgacgtggg taatgatgtt
    40561 ttcgatctgc taaaccaacc ttagccaatt ctgcttgcgc cagtttagtc gcttcttggt
    40621 cagacagttt tttgaccacc ttaagacctt ctttgacatt ctcaagggct gtacgacgct
    40681 caaaaagatt aaattgttga aaaaccatgg caagtttccg acgtaaaata aggacttgct
    40741 ctgtggtaat ggtctcaaaa tcaaccgtaa agtcaccaat gctaatggag cctgaatctg
    40801 gtttttccaa atagtttagg ctacgaagga aggtcgattt ccctgctcct gaagcaccaa
    40861 ctaaagcaat cacttgacct ttttcaatat caagagccaa actatctaaa actttttgcc
    40921 ctgagaatgt cttgctcaaa tttctaattg taatcatcaa cgcaattctc ctaacttttc
    40981 atttctagct tgttctggtg ctttgatggc catcttgttt tcaatcaagc gacctacttg
    41041 ctccatcaaa atactgatag accaatagac aagagcaaca gagatataac gttcaaaata
    41101 acggtaatct gatccgccta gaatttgagc ctgggcaaac atttcgacaa tccctgcatt
    41161 aaaggcaagc gatgttcctt tagttaagcc aattaaccca ttaatcaagg ttggaatagc
    41221 cacaacagtt gcattaggaa taatgacacg acggtaaacc tgcacagaag tcatgcctag
    41281 actttttgct gcttcaattt cacctgtatc tactgataaa atggctgccc gaatagtttc
    41341 actagcgtag gctgcttcat taaaagcaaa ggctgtaatg gcaaaaatag aagccggaat
    41401 tgcattaaca ttccaatcaa agccatactt ctgattgaga aattttagaa agaggggaat
    41461 accgtagtag gtcaacatca actgtaccaa aataggagtt cctcgcaaga aactcacaaa
    41521 aatagcttga atagggtata gtagcttcac tttattaatt ttgacaaggg caaaaatcaa
    41581 agccaaaacc aagccaaagg ttgctcctga tagtgtcaaa ccaagcgtaa ttggaagccg
    41641 ttggataata tttggaatgg catcaaaaac agcatgccaa ctaaaaagtt tcccatgtgg
    41701 aatcggtgag atgaggtaat cataaaaagc ccaaccactg gttaaaaaca ctgatgtcat
    41761 gtatttcccc tttgtatttg tttgtcttaa tattctaaca ctcttagacc cacatgtaaa
    41821 atagtaaatt cgtattatag caataagcaa aagctatgat cactttttgt gttaacaaat
    41881 ggtaaacaat acaagtagca ggtgtaaaaa aagcaagatt agatgccaat tgatcacttg
    41941 cttgctcttt gttcttaaaa atgttgtttt ttggccttac gctcagcgcg gcccttagca
    42001 cgattttcag cacgacgttc tttgcgacgt ttttcatcaa ccgcccactg aatttttttc
    42061 ttgtaacctg gtttgacttt tttctttttc tttttgacca aaccaatcat ttctgtgtct
    42121 aatttttgat aggctttttc acggttttga cggcgatcac ggtcataggt atcttgaaat
    42181 tctccatttt tgagcacctt cggtgtaaag gcaatcccca ttttttccag ctctttgata
    42241 tctgagtcgt cacttggctg gtaaagtgta atggcagttc ctgccatacc atttcgacct
    42301 gttcggccta cacgatggac aaagaaagac aagtcttgtg ggatggcgtc attgatcaca
    42361 tggctgaccc cttcaatgtc aatcccacgc gctgctaagt ctgtggcaac aatgtattca
    42421 aagtccagtt ttttgacttg gttcatgatg cgcttacgtt ctcttggagg aatgccccca
    42481 tgaatcttag ccacttttaa gccattagct gttaaaaagg catgcaaatc atctgcgcgt
    42541 tccttggtat tgacaaaaag catagccata taaggctgca tggttttgag aatctctaac
    42601 agttgaccat tcttatcacg cccttttgtc gacacaagcc agttatcaat ggtatctgcg
    42661 ataacggtct ttgtcttgat ttgttcaata acaggattgg tcaagtattt tttcaaaaag
    42721 ggttgtaatt tctgtggaat agttgctgag aacaccaaaa tctgaacaga ttttggaagc
    42781 gaagctgcaa tcttatctac cgtatccaaa aagcccatgt ccatggtcat atcggcctca
    42841 tccacaacaa aggtcgttgc tttatgaatc gctaaatcac cagacttgac caagtcataa
    42901 atacgacctg gggtcccgat gacaatatgc ggctggctgt cttttagttt ttcaatctga
    42961 cggagtttgt ctgtgcctcc aacatagttg gccaaacgaa tctcttcttg gaagtgctta
    43021 gcaatctgtt tacaagcatc aaaaatttga gttgctaatt cacggctagg tgctgtaata
    43081 acgacttgca cttctgcttt agcttcatca agtttttcaa aaatgggcaa caaaaaggtg
    43141 tgggttttcc ctgaacctgt ttttgattcc ccaactaagt cacgaccgga gttaacaata
    43201 ggaatcagcc gcttctggac ctctgttgga ttgacaaagc caatttcttc cagcgcttgc
    43261 tgaacgtatt gcttaaaatg ataatcttta aatgacatgt tttacctcgt tttcttccat
    43321 attatatcat tattgttaga gacaagcaaa aggagtggga caacactcgc aaaatcagca
    43381 tttgtgggtc atctccactc tcttattgat gatgttaatc aaaatgctat tggtgactat
    43441 tcttgataat cccccttaga acacgtataa gatagctaaa actagtaaac tagctagact
    43501 tcctactccc cacaaaaaag catctacctg ccattctgac cacttcttgc ctttaccaga
    43561 caagcctccc aattccaaat ggtggtggaa aggcgtcatt ctaaaaatac gacgaccttc
    43621 tccatatttt ttcttggtgt acttgaaata ggacacttgc aacatcacag aacttgtttc
    43681 aagaacataa acgatcccaa taatcaggag agtccattct tgacgaagcg caatagaaat
    43741 ggcagccaac atagctccaa gggctaaact acctacatct cccataaata ctttagcagg
    43801 tttgtgatta aagcagaaga agccaagcaa ggctccaatc attgctccaa tcagtaacaa
    43861 aacatcaaat tgactctgaa cgtaggcaat aacgccgtaa gtcactagac taatcaccac
    43921 tgagatagaa gctaagccat cgataccatc tgtcaaatta acggcatttg aaaaaccaac
    43981 cacccaaaac aaaacaaaga ataggtagaa aattcccagc ggcagctgat aaccaaacac
    44041 attaatagag gaaatgccac ttggactaac atgtaaaaaa tagaacatca atcctccaac
    44101 caactgcaag gctaactttt gtttggctgt caatccttca ttgatttgct taaaaatttt
    44161 taaaaaatca tccaaaaatc cgataatccc gtaaatgaca acaattgata aaatgcctga
    44221 aatcaaagct aaactttgag tgtttttgat cgaaaataga ctaaccaata acgatactgc
    44281 cgtagctact aaaagaaaaa cagttccccc catagtcggt gttccagctt tagctaaatg
    44341 ttgcttgaca tcttcatgca tttgttgccc accaattttt ttcaattgat agaatttgat
    44401 aaaataaggc attgtgaaag cagataccat aaaggatatg attgctgcaa taagggttaa
    44461 aaacatgtta atctcctaaa gtaatggtca ttttttttat ttttttcaag gacttaccaa
    44521 catcaacact ttgtttcata acacgaccag aatctgttcc tttaaagctg atgtctattc
    44581 cagtccattt agcaaaggtt ttaacattgg attttgtcca gccatacatg tctggtacct
    44641 ccacaaaacg gtctgataat atgagaactt gttggttttc tgttaacgtt tgaccgggct
    44701 gatgcgatac ttttttgatc ttgctgccag taccaaggac aactggctgg acaaggtttc
    44761 gacgcaactc gcttgatgtc tcaccaggat tctttcctac aaagtttggt aatttataag
    44821 ttgtttgacg attagcatct gatactactg gcttagttag tgtatcttgc attaagtatg
    44881 cttcttccaa tactgggtta accacatctt gccaaaaaag gggaccaaaa tgttgtggtt
    44941 tagtcatagt aacatacatc aaaaagtctg gtttatcagc tggcaccatt gccacaaccg
    45001 aatagacata gttagtcaat ccaccatctt gataaccact tccatcttct gaaccaattt
    45061 gtgctgttcc tgatttaaca gcaacaggta aatcacccac tttaataatt ggtccaaatg
    45121 tttttgaata gagtgttcca aactcagggt ctgttcctac accaatcatg tattgtcttg
    45181 tttcactagc ggcttttttt gatacaggtt ttccaacaat ttctttattt gccgttctaa
    45241 aacttgctgt gttaggatca taaatttgac tgataaattg tggctctaac atctcaccat
    45301 tattagaaat agcagtaaag gctctaagca tttgaatctg ggttacagaa atcccttgac
    45361 caaaagcgct catagcttga gtcacgatat tatcagaagg aaatatacct gcgtcttcat
    45421 cttttaaacc aaaacgagta ggaaaaccaa agcggaactt cgtcaaataa ttcatccatt
    45481 ttgcattacc cattttttgt tcaagtttag tcatcccaac gttacttgag aaggcaaacc
    45541 cttgtgcata attcatgtac tgtcctgtgg aaatgccttc gttaatagac cagtcttgaa
    45601 tagtagcatc tgcaattgtc aaaccattag cattgctaaa ggtttcgttt gggttgaaaa
    45661 ctttatcatc aatagccgct gccagagtca tcactttcat ggttgaacct ggttcaaaat
    45721 ttccttgatg aagtgcactg taccatttgt agttcgtatt ttcaagtcct ttcagagtat
    45781 cagcattata agtggggcgt tgtgttgttg ccaaaatttc accagtttta gcattaacaa
    45841 gtgttgcact ggccaactga ccatttgatt tggcttgaaa aacatccatc tgggtttcta
    45901 agaaggtctg gataggctca gatagcgttg tgtaaatatc tttgccatca atagctttct
    45961 tgacagtctt acctgtaccc aagagtgtgg tcccatttcg atctttttga taagtaataa
    46021 caccatcttg acctgataaa attttatcaa aagaagcttc tagacctgtt tttccaacta
    46081 aactcttaac acctgtcttt ttatcttctg ttagagatgc taggcctata aattctgaag
    46141 caaatgtccc atttggatac atacgaccag gactagttgt gaaagcaatt cccttgattt
    46201 tggcatcttc catagccttt tgaatagtag acatagtact atatgaaatg ccagaccctg
    46261 acggtccaaa cgagacttgg aaaagtcctt tacgcttaag ctgtttaatt acatctgttt
    46321 ttttcattcc cagatgcttt tttaaaatat cagctactgt ttcatactga gaaggttgta
    46381 catataactt ttcatctgaa gccgagacaa atgatttatc caaaattgcg tatatgctat
    46441 aagtcgtaga atccactgca atagctgtac catttcgatc ataaatggtc ccacgcttag
    46501 cttggatcgt aacggtttct tgataaacct tcttcgcccc ttctgacaaa ctaactccaa
    46561 acttttgatc tgttccaata ataatcatga aattaataat gaaaataaag aaaataaaga
    46621 tagttaagag catcatattt tgtccaactc gaacgcgatt ttcgactgga gttctcctat
    46681 cgcgcacaac ataatctaaa acatattttt gccatttttt catagattac tcgactttct
    46741 tgatattatt attacggttg cttaagcctg ctttaccagc aatatctata atacgatcac
    46801 ggcgagataa ctcatttact tcttgcttgg cattattaag ctctagtttt tgatccgaaa
    46861 tatgactatt taaactagtg atttcttgtt gtagctgcaa cttacgactt tgcaggtaaa
    46921 taatacttac tgccatcgta atcgctgtta caatgatagc agtataaaaa gccttctcaa
    46981 ttctagagaa agtttttatt cgtttttgca aggcatttgt aactgcctga gttctttttt
    47041 catttgtcat aggcttattt ccgaattttt ttggcaacac gtagcttggc tgagtgtgcc
    47101 cttttattag ctgttaactc tgaatgacta ggtaagatcg gcttacgtga aacaagttca
    47161 aacttaggtt tcatatcttc aggaattaga ggaagccctt ttggcacatc caccgtacta
    47221 gcttctttaa acaactgctt ggttaggcga tcttccagag aatggaaggt aataactgag
    47281 atacgaccat caagggctaa taattccata gcgtcctgaa tagattcatc ggccgctccc
    47341 aattcatcat tgacttcaat gcgaatagct tgaaaaatct gtttagcagg gtggcctttt
    47401 ttcttcaact ctttagctgg ctttgctgcc ttaatcaatt ctgccaactc tgttgttgtc
    47461 tcaataggct taatagctct tgcttgttca atttttcgag cgatctgctt ggagaattta
    47521 tcttcaccat atttgaaaaa aatcttaacc aaatcattga atggataggt attcaccact
    47581 tcgtaagctg ttaagagcga ctgacgatcc atgcgcatat ccaatggagc atcttgttta
    47641 taagaaaacc ctcgttctct ttcatccaat tgcgggctgg aaacaccaag gtcatataag
    47701 ataccatcaa tttcatcaac tccaagcgct gttaaacgtg ctttgaggtg tctaaaatta
    47761 tctttaataa aagttacctg tcctttgtca atataagatt tgagggtaac ttgtgcattg
    47821 tcaatagcct tttggtcttg gtcaaaacaa tagaggtgcc cttcttcacc aagtttggac
    47881 aacaaataag ctgagtggcc tgagccacct agcgtcgcat caacataaat cccatcaggc
    47941 tttatgtcaa gcatgtccac tgtttcgtga aggagtacgg tcacgtgatg aaattctttt
    48001 gtcataactt taattgtacc atacttcaaa aggtttagaa atgaaaaagt aagagaaaag
    48061 gatttcattc tcgtgggaat cttcctcttc tctaatcttg ttctttttgt tcgctatcag
    48121 ccaacttagc aagcactgac ttagccactg cctctagagt ttcaactgct tgtaaaagat
    48181 ttttagcttc cttaatcaca caacaatctg tcagcgggtt gtctaaccaa ataccaaagg
    48241 ttttatccca aatcgtattt ggtaagtcag ctaataatag cctatcgacg tctgccagct
    48301 atcttcggca gttttgaaga gtaacttgta agtctattaa taattggttg accttgctca
    48361 ttatttcgac gtttgatcca gctaaccagc ataccatctc caaaaaaaaa caaaatagcc
    48421 ccaatttcgg acaattttca attccaaatg aatcacctga atctgatgta aaagttcttc
    48481 taaagtaacc tttgcttctt ctttttctct ttcattagtc attaagggac cttatagtag
    48541 cttattctct gatatgtcca tccccattaa tataaaattt agtgctggtc aaggcttcta
    48601 agcccattgg cccacgggcg tgcatttttt gagtagaaat cccaatttca gcaccaagcc
    48661 caaaaacaaa accatcggta aatcgtgttg aagcgttgac ataaacagca gcagcatcca
    48721 ctaaatcttg aaaggtctct gctgccttaa tatcccttgt gatgatagct tcggaatggt
    48781 gactagtata ctgatttatc caagaaatag cttcttccaa agaggaaaca accttaacag
    48841 acatgatata atctaaaaat tcggtctcaa aatcctctgc ttttgcaggc actgcctgct
    48901 caaataacgg caaagccttg tcatctgccc gccattctac tggctgaact tgattgatcg
    48961 ctttttcaag cataggaata aaccttgctg ctacagcttc gtgaattacc aatccctcag
    49021 ctgcattgca aacacttggg cgctttgttt tagcgttgat aacaatctta gtagctatat
    49081 ctaagtcagc ttgagcatcc acatagatat gcacattccc cacacctgtt tcgatgacag
    49141 gcacttttgc tttttcctta acggtctgaa ttaatttagc accaccacgt ggaatcaaaa
    49201 catctacata atccgttgcc tgcatcaatt cttcagcgac agcatgtgag ggatcctcaa
    49261 ctagctggac agcatctggg gtgatccctg atttttccag actttgtcgg atcaacttca
    49321 ccaaagcttt atttgagtga agggcatctt ttcctcccct taggatgatc gcattattgg
    49381 ttttgaacgc cagactaaaa gcatccactg aaacattcgg acgactctca aaaatcatcg
    49441 caatcacccc tagaggaact ctcttttgga ggattttaag gccatcgagg ttagtatagc
    49501 ccttaatgac ttgtccgatt ggatcagcta agtcagcaac ctgttgaact ccctgtgcta
    49561 tcgctttaat ccgttctgaa gttaagcgca agcgatccat catgatgtca gaaataccat
    49621 gttctttagc attcgctaaa tctttttggt tagcggctaa gagagtctgt gtatcgtcaa
    49681 ctaatgcctt tgctaaggtg cttaaaaagc gatttttaat ttgcgtcgac aaaggtgcta
    49741 ttaaaagact agcttgtttt gccctttgcc ctaaccttct catatcagtc atgccttacc
    49801 tcttctatct gcttgaacca ggtgcctagt ggttgccctt caagcactct taaaatatct
    49861 ctgggattag ctccattcat caagaccatc tgtcctttgt tttcaaatac catctgagca
    49921 gactgcacct tacttagcat cccacctgtg ccaaacttac tgcccgcacc acctgctgac
    49981 gcaatgattt cttgcgtaat attagcaaca tggctgcgta gctgcgcatc ctcataaata
    50041 gtagggtttt tatcaaaaag gccatcaata tcagacaaca tgattaataa atcagctttt
    50101 gtaataccag caacaacagc agataaacgg tcattatctc caaatttagt cgcatgatcc
    50161 atttcatcca cactaaccgc atcgttttca ttaacaatcg gcacaatgcc caaactaatc
    50221 agactttcaa aagcattggt aacattggct agactttctg ggaaaaccac cacatctctc
    50281 gtcaataaaa tttgtgacac gttggtttgg tagtatgcaa aaatttgtga ataaagactc
    50341 atcatggcta cctgaccaac actggaaact gcctgttgtt tagcaagatt ggtcggacgt
    50401 ttttccattt tcaaaatatc tagtccaaat cccatcgctc ccgatgatac taaaataact
    50461 tccttgccct tattcatcaa acttgaaatc acaaaagcca gttggtcgat tttttctaaa
    50521 ttaattttac ctgttggtag cactaatgaa ctagtgccaa ttttaattac gatacgtgtt
    50581 acatcttcaa attgtcgttt catcataccc aaattatagc ataaaaaaca gccccagagg
    50641 actgtttttc cgaataatga tccctcttcg ttaaagcctc tctaagcttt tccagaaggt
    50701 tttttgaatc cataattgcg caagacctaa aaccattagt attagacaac tcaatagaat
    50761 actaatcaac agaggttgtt ggataatatt ggcaatgata acagctccaa aacctagcac
    50821 acctgcaact attaaattac caaagataag tcccattgtt aaccattgcc catctcctct
    50881 ggtaaagagt tgcgtcatgt cttgccattt taaatccaga agccggtagt cacgacgata
    50941 catcaattcc ccttgcacaa tcagtgatag ggcgtagcca agacaaaaag caatcgttag
    51001 aagaggatgc aggtgcaaca caaagagacc aaacacaaga taaatcacca taggcacaat
    51061 cagctgcaga cctacaagca agcaaaattt atccatcaag aattttttta acgttattgg
    51121 taagctttta ataaaggtaa agttatcctt ttcaagtgaa atacctactc caataaagct
    51181 ggttggtgtt gcacacatga cacccaaact aaccccaaat aataaggcta ccccaaagta
    51241 atctggggaa atatgcttaa agaaacctgt gccacgtgac aaacttggac cgataaaaag
    51301 catcacatac atcaggggca tgagataggt ttgtgtcagt aaagttgcat tttgtaacgt
    51361 taataggtga tgttttcgca acaactgcgc cagtgattga ttctgatgag gacgattaac
    51421 tggtttttta gtttgcttga ctttgttctc gttactaata taaaaagcct cacgataata
    51481 agttggcatc acttttgtga caataccata taccatagct aggataagta acaatggcaa
    51541 ccaaaagtta aggagggccg cagtagaaaa cggtgcctga acaacatcat agaatccttt
    51601 gaaataggga atagttgggt aatcagtaaa tacgccatcc gtcatcgtac gcttgttgtt
    51661 actaatatta atcgcaaaaa ttaagacgaa agcgccaaaa gttgagacaa acatcatgat
    51721 agttgaaatg agttttcgtt tgcgacttct tacaatgatt ttgcctaccc aagcattgat
    51781 ataaatagct aataccatag aactcactag taacactaaa aagagcacga tagctactaa
    51841 aatagacaaa ggatttccca agagttgcca ataggcaatt aagagaagag agataagagg
    51901 catcaaaaag acagcaccca tccctagcga cgagacaatt tttgcaatat agagttcttc
    51961 tgacgttact ggtaagtgaa tataaagttt taggtcatta ctttcataaa aaatggtgta
    52021 aagagagcta aaggctgtca aggttgacat gataaaaaac atagcaacgt caaaggagaa
    52081 aagtcctgga taatgactga aatcgacacc aataaacata aaaaggtaaa tcaccaaaaa
    52141 catggcaatc attaaggcct gttgccttat catgctttta taggctttga agttttcttt
    52201 cgggtgtttt tcctgacgct ttttgaggtt agctaaactt tgtggattgg aataaagaat
    52261 gtttatcttg ataagttccc aaatagtaga ccaattcatg ccatcacccc tcttcttgcg
    52321 ccttacgccc agcgagttca aggtagatgc tctccaagtc tttgtcagga tggtgttctt
    52381 tcaactcatc aatcgttcca acaaaaatca atttcccttt ttttagaatc ccgatacgat
    52441 cacataactg ctcagcgact gatagcacgt gagtcgaaaa taagactgta tgtccagaag
    52501 ctgcatgagc tttcatcatt tctttaaggt caaaagaagc ctgaggatcc aaacctgtta
    52561 atggttcatc caaaatccag atgttaggat ttgatacaag agcaccaatc acaatcactt
    52621 tttggcgcat cccatgtgag aaactatcaa tggtttgatt aacttcttcc ttcagttcaa
    52681 aaagtgttgt cagctgtgct aaccgttctt ctctgtcctc atctgacacc ccataaattt
    52741 tagctaaaaa ctgccaatac tcatttggag ttagattcaa gaaaatatca ggagaatctg
    52801 gcacataagc aatttgtttt ttgatagctt ctctattttc tgtcagaagt tgaccatcca
    52861 caaatacttc gccataactc gcttcgataa tagaagtcaa aatgctgatg gtcgtggttt
    52921 tacctgcacc attatgtccg ataaggccaa aaatttcacc gtcattgatg gtgacgttta
    52981 aatcgctgag agcttctttg tcgccataca actttgaaac atgtttaaat tctatcatgg
    53041 tatccttttt ccttttcttc tctttttctc cctagactaa tgaggcttcc tctaaaatat
    53101 acttttccaa tgactgctta aaacggcaaa gcgattttgg aagtaaaatg tcattatcaa
    53161 gtaagtaatt atccacatct tggtttagtt ggtaggcaac aagaagtggg ttactgtgtt
    53221 taattaatct attagaagct gctaaaagta gctgcgacaa ggccacattt tcacgatttt
    53281 ctggataatc ataagcctgt ctaatc
//
LOCUS       DAUGQX010000008        53118 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUGQX010000008 DAUGQX010000000
VERSION     DAUGQX010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53118
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.008"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(155..1222)
                     /locus_tag="VIA51_000394"
     CDS             complement(155..1222)
                     /locus_tag="VIA51_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEQ8682363.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDGIPPI
                     SLTQKTTATTSENWHHIDKDGLIPLGISLEAAKEEFKKEVEESRLSEAQKETYKQKIK
                     TAPDKDKLLFTYHSEYMTAVKDLPASTESTTQPVEAPVQETQASASDSMVTGDSTSVT
                     TDSPEETPSSESPVAPALSEAPAQPAESEEPSVAASSEETPSPSTPAAPSTPAAPETP
                     EEPAAPSQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSL
                     VSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIAT
                     MTLMSLFGSLLVTKRQKETKK"
     gene            complement(1319..4813)
                     /gene="scpA/B"
                     /locus_tag="VIA51_000395"
     CDS             complement(1319..4813)
                     /gene="scpA/B"
                     /locus_tag="VIA51_000395"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEQ8682364.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTAVSEEAPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATI
                     RDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAK
                     KEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGA
                     MPEAQLLLMRVEIVNGLADYARNYAQAIIDAVNLGAKVINMSFGNAALAYANLPDETK
                     KAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPD
                     KQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIE
                     RGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENP
                     QKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKL
                     SGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFS
                     PRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYY
                     QATVQTDKVDGKLFALAPKALYETSWQKITIPANSSKQVTIPIDVSQFSKDLLAPMKN
                     GYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDA
                     KDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTF
                     AKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNV
                     VWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISS
                     GAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDED
                     LPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEG
                     HSNKPEQDGSDQAPDKKPETKPEQDGSGQAPDKKPETKPEQDGSGQTPDKKPETKPEK
                     DSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTKDQLPTTNDKDTNRLHLLKLVMT
                     TFFLGLVAHIFKTKRTED"
     gene            5247..6633
                     /locus_tag="VIA51_000396"
                     /pseudo
     CDS             5247..6633
                     /locus_tag="VIA51_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(7031..7876)
                     /locus_tag="VIA51_000397"
     CDS             complement(7031..7876)
                     /locus_tag="VIA51_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis inhibitor protein"
                     /protein_id="HEQ8682365.1"
                     /translation="MNIRNKIENSKTLLFTSLVAVALLGATQPVSAETYTSRNFDWSG
                     DDWSGDDWPEDDWSGDGLSKYDRSGVGLSQYGWSKYGWSSDKEEWPEDWPEDDWSSDK
                     KDETEDKTRPPYGEALGTGYEKRDDWGGPGTVATDPYTPPYGGALGTGYEKRDDWRGP
                     GHIPKPENEQSPNPSHIPEPPQIEWPQWNGFDGLSSGPSDWGQSEDTSRFPSEPRVTE
                     KPQHTPQKNPQESDFDRGFSAGLKAKNSGRGIDFEGFQYGGWSDEYKKGYMQAFGTPY
                     TPSAT"
     gene            complement(8065..9519)
                     /gene="emm"
                     /locus_tag="VIA51_000398"
     CDS             complement(8065..9519)
                     /gene="emm"
                     /locus_tag="VIA51_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein"
                     /protein_id="HEQ8682366.1"
                     /translation="MAKNNTNRHYSLRKLKTGTASVAVALTVLGAGFANQTEVKANGD
                     GNPREVIEDLAANNPAIQNIRLRHENKDLKARLENAMEVAGRDFKRAEELEKAKQALE
                     DQRKDLETKLKELQQDYDLAKESTSWDRQRLEKELEEKKEALELAIDQASRDYHRATA
                     LEKELEEKKKALELAIDQASQDYNRANVLEKELETITREQEINRNLLGNAKLELDQLS
                     SEKEQLTIEKAKLEEEKQISDASRQSLRRDLDASREAKKQVEKDLANLTAELDKVKED
                     KQISDASRQGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLD
                     ASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQ
                     LAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQL
                     PSTGETANPFFTAAALTVMATAGVAAVVKRKEEN"
     gene            complement(9704..11293)
                     /gene="mga"
                     /locus_tag="VIA51_000399"
     CDS             complement(9704..11293)
                     /gene="mga"
                     /locus_tag="VIA51_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Mga"
                     /protein_id="HEQ8682367.1"
                     /translation="MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISML
                     TLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFR
                     DFNSLEELAEELFVSLSTLKRLIKKTNAYLMHTFGITILTSPVQVSGDEHQIRLFYLK
                     YFSEAYKISEWPFGEILNLKNCERLLSLMIKEVDVRVNFTLFQHLKILSSVNLIRYYK
                     GHSAVYDNKKTSQRFSQLIQSSLEFQDLSRLFHLKFGLYLDETTIAEMFSNHVNDQLE
                     IGYAFDSIKQDSPTGCRKVTNWVHLLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDI
                     TANYLFFDYKKSYLNFYKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFIT
                     WENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYVGEFFSITNFNELDALTIDLEEIE
                     KQYDVIVTDVMVGKSEELEIFFFHKMIPEAIIDKLNAFLNISFADSLPLDKPINPLDF
                     HRKEVILPTPPNKLHAPPSTT"
     gene            complement(11969..12220)
                     /locus_tag="VIA51_000400"
     CDS             complement(11969..12220)
                     /locus_tag="VIA51_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682368.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            complement(12299..13900)
                     /locus_tag="VIA51_000401"
     CDS             complement(12299..13900)
                     /locus_tag="VIA51_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8682369.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTAD
                     TDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKGPEKA
                     TDKTPEPNRDAPKPIQPPLAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAY
                     THNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAE
                     SSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQD
                     LKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKIT
                     SGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDW
                     QRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGT
                     ISYRTFTAEQASLLTYVVGDKLPRP"
     gene            complement(14002..15390)
                     /locus_tag="VIA51_000402"
     CDS             complement(14002..15390)
                     /locus_tag="VIA51_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8682370.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKC
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            complement(15387..16040)
                     /locus_tag="VIA51_000403"
     CDS             complement(15387..16040)
                     /locus_tag="VIA51_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682371.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            complement(16134..17351)
                     /locus_tag="VIA51_000404"
     CDS             complement(16134..17351)
                     /locus_tag="VIA51_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682372.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            complement(17364..18038)
                     /locus_tag="VIA51_000405"
     CDS             complement(17364..18038)
                     /locus_tag="VIA51_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682373.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            complement(18025..19293)
                     /locus_tag="VIA51_000406"
     CDS             complement(18025..19293)
                     /locus_tag="VIA51_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8682374.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            complement(19716..20000)
                     /locus_tag="VIA51_000407"
     CDS             complement(19716..20000)
                     /locus_tag="VIA51_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEQ8682375.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            complement(20147..20443)
                     /locus_tag="VIA51_000408"
     CDS             complement(20147..20443)
                     /locus_tag="VIA51_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEQ8682376.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            20687..20923
                     /locus_tag="VIA51_000409"
     CDS             20687..20923
                     /locus_tag="VIA51_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682377.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPAAHGPCD
                     DIHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            complement(21198..22127)
                     /gene="prsA"
                     /locus_tag="VIA51_000410"
     CDS             complement(21198..22127)
                     /gene="prsA"
                     /locus_tag="VIA51_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8682378.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTTAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(22607..22912)
                     /locus_tag="VIA51_000411"
     CDS             complement(22607..22912)
                     /locus_tag="VIA51_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEQ8682379.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQKQINSLD"
     gene            complement(22914..24110)
                     /gene="speB"
                     /locus_tag="VIA51_000412"
     CDS             complement(22914..24110)
                     /gene="speB"
                     /locus_tag="VIA51_000412"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEQ8682380.1"
                     /translation="MNKKKLGVRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            25050..25892
                     /locus_tag="VIA51_000413"
     CDS             25050..25892
                     /locus_tag="VIA51_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8682381.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            complement(26133..26948)
                     /gene="sdaB"
                     /locus_tag="VIA51_000414"
     CDS             complement(26133..26948)
                     /gene="sdaB"
                     /locus_tag="VIA51_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEQ8682382.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            27312..27821
                     /locus_tag="VIA51_000415"
     CDS             27312..27821
                     /locus_tag="VIA51_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEQ8682383.1"
                     /translation="MSTDHQLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGYSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            complement(27903..28991)
                     /locus_tag="VIA51_000416"
     CDS             complement(27903..28991)
                     /locus_tag="VIA51_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEQ8682384.1"
                     /translation="MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(29048..29716)
                     /locus_tag="VIA51_000417"
     CDS             complement(29048..29716)
                     /locus_tag="VIA51_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8682385.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGEIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIEQLAEAINRENA
                     NSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAVHH
                     RKSI"
     gene            complement(29729..32146)
                     /locus_tag="VIA51_000418"
     CDS             complement(29729..32146)
                     /locus_tag="VIA51_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEQ8682386.1"
                     /translation="MTETKSPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWKALESDFAGERGEDIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            complement(32356..33660)
                     /locus_tag="VIA51_000419"
     CDS             complement(32356..33660)
                     /locus_tag="VIA51_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8682387.1"
                     /translation="MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            complement(33670..33978)
                     /locus_tag="VIA51_000420"
     CDS             complement(33670..33978)
                     /locus_tag="VIA51_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8682388.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            complement(34006..34326)
                     /locus_tag="VIA51_000421"
     CDS             complement(34006..34326)
                     /locus_tag="VIA51_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8682389.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            complement(34614..35594)
                     /locus_tag="VIA51_000422"
     CDS             complement(34614..35594)
                     /locus_tag="VIA51_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEQ8682390.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRQQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            complement(35610..36356)
                     /locus_tag="VIA51_000423"
     CDS             complement(35610..36356)
                     /locus_tag="VIA51_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8682391.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLDVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKVITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            36482..37255
                     /locus_tag="VIA51_000424"
     CDS             36482..37255
                     /locus_tag="VIA51_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEQ8682392.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLVDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            complement(37492..37668)
                     /gene="secE"
                     /locus_tag="VIA51_000425"
     CDS             complement(37492..37668)
                     /gene="secE"
                     /locus_tag="VIA51_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEQ8682393.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(37682..37834)
                     /gene="rpmG"
                     /locus_tag="VIA51_000426"
     CDS             complement(37682..37834)
                     /gene="rpmG"
                     /locus_tag="VIA51_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8682394.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            complement(37883..40219)
                     /locus_tag="VIA51_000427"
     CDS             complement(37883..40219)
                     /locus_tag="VIA51_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8682395.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPATALQRSRAYEGSPKSRPAWLQKLEAVLPSPQRPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            complement(40258..40638)
                     /locus_tag="VIA51_000428"
     CDS             complement(40258..40638)
                     /locus_tag="VIA51_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8682396.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            41214..42215
                     /locus_tag="VIA51_000429"
     CDS             41214..42215
                     /locus_tag="VIA51_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8682397.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHSVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLTCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            complement(42304..43944)
                     /locus_tag="VIA51_000430"
     CDS             complement(42304..43944)
                     /locus_tag="VIA51_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682398.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDKSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            44191..45687
                     /locus_tag="VIA51_000431"
     CDS             44191..45687
                     /locus_tag="VIA51_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8682399.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMTSVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGVMWLSIGSPRNAPYLPYLGNISRTYEAYQ
                     EKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISDL
                     VVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVKEKPKNKKGLNRS"
     gene            complement(46315..46629)
                     /locus_tag="VIA51_000432"
                     /pseudo
     CDS             complement(46315..46629)
                     /locus_tag="VIA51_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535316.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(46890..48521)
                     /gene="groL"
                     /locus_tag="VIA51_000433"
     CDS             complement(46890..48521)
                     /gene="groL"
                     /locus_tag="VIA51_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEQ8682400.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPATPAPAMPAGMDPGMMGGF"
     gene            complement(48557..48847)
                     /gene="groES"
                     /locus_tag="VIA51_000434"
     CDS             complement(48557..48847)
                     /gene="groES"
                     /locus_tag="VIA51_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEQ8682401.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            complement(49025..51469)
                     /locus_tag="VIA51_000435"
     CDS             complement(49025..51469)
                     /locus_tag="VIA51_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8682402.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKDIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            complement(51469..51930)
                     /locus_tag="VIA51_000436"
     CDS             complement(51469..51930)
                     /locus_tag="VIA51_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEQ8682403.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            complement(52126..52329)
                     /locus_tag="VIA51_000437"
     CDS             complement(52126..52329)
                     /locus_tag="VIA51_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEQ8682404.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            complement(52848..52918)
                     /locus_tag="VIA51_000438"
     tRNA            complement(52848..52918)
                     /locus_tag="VIA51_000438"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52884..52886),aa:Cys,seq:gca)
BASE COUNT        14427 a        10790 c        10340 g        17561 t
ORIGIN      
        1 catcttttat cacagcaact gaagagataa gcaaaagaca attgttgaca gctatttgtc
       61 ctaacttctt tttgatgagg cagcacatct aaaaaaatag agagaaccaa attggttctc
      121 tctattaaat aagctcttat cagtttaagt aatactattt tttagtttct ttttggcgtt
      181 ttgtgactaa aagactgcca aatagagaca tcaaagtcat agtagctata aagagtggct
      241 gtgctttttc acctgttgaa ggcaagtact tacctgactc atgggcccta acctgtcttg
      301 acaatgagcg atttggagag taagactgtt cttgctcttc ttttttatca gaagatctct
      361 ttgaagttgg ttgttgaacg gtttgttctg aaacaagtga agaggctgct ggtttttcag
      421 ctgctgaaga tggcttatca gagtctttag taacagctgg tggcgtctga gtctctgatt
      481 cagctggagt tgatggagac gggcttgtcg tagctgctac tgaagattct tcactctcag
      541 ctggttgaga tggagctgct ggttcttcag gagtttctgg agccgctgga gttgatgggg
      601 ctgctggagt tgatggagat ggggtttcct cagaagatgc tgctactgaa ggttcctcac
      661 tctcagctgg ttgagctgga gcctcagata aagctggggc cactggactt tccgaagatg
      721 gggtttcctc aggagaatca gtcgtaactg atgttgaatc acctgtcacc atcgaatctg
      781 aagctgatgc ctgtgtctcc tgcacgggtg cctcaactgg ctgagtagta gactcagtag
      841 acgctggaag atccttaacg gctgtcatat actcactatg atacgtgaat aatagcttat
      901 ctttgtctgg tgcagtttta attttttgtt tatacgtttc tttttgtgct tcagataaac
      961 gtgattcttc tacttctttt ttaaattcct ctttggcagc ttctaagctt atacctaaag
     1021 gaataaggcc atccttatca atatgatgcc aattttctga tgtagtggct gtagtctttt
     1081 gagtaagaga gattggaggg atgccatcta cggcataggc aacctttcct aaaaagagac
     1141 tcgcaattgc tatactcgtt accccaacgc tcagtttgcg aatggaatag cggctgtgtt
     1201 tgttattttc tgctctacgc atattgtcct cacatatcta tttttatact gctatgcctt
     1261 cttttgaaaa gaagactgat ctaactcatc atcaatagta gccatctgat cagttgtact
     1321 aatcttcagt gcgttttgtt ttaaagatat gagctactaa tcccaagaag aaagtggtca
     1381 taactaactt aaggagatgt aaacgatttg tatccttgtc attagtcgtt ggtaactgat
     1441 cttttgttga tgcttttgta gctaaagcac gcttagaaga tcgtttctct agagtacgag
     1501 aaggttgacc tttttgagga gttttacctg gtgtttgacc tgaactatct ttttctggtt
     1561 tagtttctgg ttttttatct ggtgtttgac ctgaaccgtc ttgttctggt ttagtttctg
     1621 gttttttatc tggtgcttga cctgaaccgt cttgttctgg tttagtttct ggttttttgt
     1681 ctggtgcttg atctgaaccg tcttgttctg gtttattaga gtggccttcc aatagcttag
     1741 tcactggtgt ataagtgatg ttaccagcca tatcttcaac aacataagta aagtctgaca
     1801 ttttcaatgg aacagtagcg ccttccattg tttcagcctc ttcaggaaga gtaaaggtac
     1861 catcttcatt tggagaaata tactctgttg ttggcagatc ctcatccata taagtgtaag
     1921 caatacgctc acggtaaacc ggttggctgg tttttggttt agatgcaagt gtcaaacgac
     1981 gatcttctgt tgagaatgtt gccgatgttg cgacttcagg tgtcgtattg tctacaatca
     2041 catcaaaatc agtgtgttgt tcttttgcac ctgagctaat cggagtgtag cgaacacgat
     2101 aggtgtatgt tccgttagca acaactttgc cgtctttatc tttaccgtcc caacgcgttt
     2161 tttcaaaacg ggttgaacca agtgtgcttg ccaagtcatt gttgtagttt ttaacaactt
     2221 gctcggttac ctcacttgtc caaacaacat ttccttcttt gtccaagact tcagccacaa
     2281 ggtttttagc attacgcaag aaagtacctt ggaattggac ataatctctg ttaccgtccc
     2341 catttggaga gatcgcagca tatggcttgc cattagcgtg acggtggata tagtagtggc
     2401 tatcatcgtc ttgttttgca aaagtacctg caaaaatggt ttctgtgatc tctgaagatt
     2461 cgatatcctc tatgttttca accccttctt tgacagcttt aataatcgtc catggattag
     2521 actctgtagt aagtgctgta aagttatttt tcagagcgta aaactgtaat ccatcaccat
     2581 ctaattggtc tttggcatca ctatttgctt catgatagta gctgctaccg tctttgctat
     2641 catagattgg tttttctaag gctgacagat tgccaaaatc acctcggaaa ccaatatagg
     2701 gaatactcat aagctcttct tttgtaggat cttgtttgaa acgaacaaaa ccttctaaga
     2761 aatagccatt tttcattggg gcaagcaagt ccttgctaaa ttgactaaca tcgattggaa
     2821 tggtgacttg tttgctgcta ttggctggaa ttgtgatttt ttgccatgat gtctcataca
     2881 atgctttagg agccaaggca aagagttttc catctacttt atctgtttga acagttgctt
     2941 ggtaatacaa ctcttgaggt ttatcagatt tgttgtgaac tgttactgtt acttcaaatt
     3001 tatcagaaac attgttcagg tgaaccttgc ttgaggtatt atccttatct gtcacataca
     3061 tcgttgctgc tgaagctttt ttagcatcga ctgctcctgc tccttgttgg cgaggagaaa
     3121 aataagcttt ttcatcttca tcatataagg cagttgctga gctcatcaat acttttttag
     3181 ctaaatcaag acgctctgat ggtgtcatat caggatactg tgtctcatat tgcttttgca
     3241 acagtcccat gatacccgct actaatggcg cagacatact agttccagaa agtttggcat
     3301 acttgttgtt agccactgat gacaaaatat cttggccggg tgctgcaata tctggcttaa
     3361 tattgccgtc agctgtcaga ccccagcttg agaagcggct tagtttggtg ccacttgctg
     3421 ttggcaatac cttaggtgtc gcattgaagg tgatggtttt ttggggattc tcttttaata
     3481 agagaccatc ttttcgactg ataaaggccg caggcatctg atcaacattt ggcaattcaa
     3541 tcgggaagcc cttgtcctga ttgtcataga tcaagactcc tacagcacca gcttttttag
     3601 cgtttgcaat cttatctttg aaatcaatat cgccacgttc aataagggca atcttacctt
     3661 tgacatcctt aaaatcatcc tctttcatcc cacgattagc ataagcatag tcgtaagcct
     3721 tgtttggctc aaaacggttt gttgaaagaa caggcatttc tttatcttgc tgatcggctg
     3781 ttttgaccgt agcagtttca gtgagctgtt tatctgggct gtaagaagca actgtcaatg
     3841 ttgagtctgc cgctgcaggt gtcccaacca ccccataatc aggatgatct gctagaggta
     3901 gacgggtctt gcccccaaag ctactatcat taccagctga ggtcacaatg ctaacacctt
     3961 ttgatttggc atagtcaaag gcttttttgg tttcgtctgg aaggttggca taggctagtg
     4021 cagcattacc aaagctcata ttaatcacct tagctcccaa gttgacagca tctatgatag
     4081 cttgagcgta gttacgagca tagtctgcta gtccatttac aatttcgaca cgcatcaaaa
     4141 gcaattgagc ctcaggcatc gcaccttcta ggcggtaagg ttctttcgtt tcagatggag
     4201 catttcctga caagatccct gacacgtgtg tgccgtgctc ttgatcgaca gcggttttac
     4261 catctttact atagtcgtgg taataagcaa ccttatcatt gacccactcg ccataggtaa
     4321 taccgtgctc ttttttagct ttttcaagat cttcttttga ttggtaacgt gctttggttt
     4381 tgtctgttaa gcgccacgct tcatgatttt tatcaaaacc agcatcaatc actgcaacaa
     4441 cagtcccagc tcctttgcct gctttttcct gcagggtttt gacctgagaa gggtcgttca
     4501 aatccctaat agtcgctttt gaggttgctg gtgtatcagc agttttagca ggagcttgag
     4561 gggctagatc attagcgtca tctgctattg tttcttctgc gtcatcagga gtttgtgggg
     4621 ttttggtttc ctttgatgat ggtgcttcct cagaaaccgc tgttggttgt ggggtttcta
     4681 cagcttgttc ggtagcagga gtgtcttctg tcacagtatt tgctttaatg tctgattgtg
     4741 cattgagcaa gatgctcgta gacatgagcg caatggcaag tttatcaaat ggtaattttt
     4801 gttttttacg caatgtgtcg tcctttcctg atgagagact ttgtctttat gaccattaag
     4861 aaaagagaga atcaaacgat tctctcctag ctgtccatct gtgcgtagag aaataaggat
     4921 aacgtctttt ttaaagagca aacaggggtt atttgcatat gatacagcta tttttcttgc
     4981 ttttgtcata atgattaaat gtatctcatt tatcaattat attaataaca tatttattat
     5041 aaaacaaaga tgattattag taaaggtcag ctttttaaga gttgcttagt ttgtgacctc
     5101 cttatcctca ttcttttaga cataaaagag agaaccgatc ggttctctct tcagactgaa
     5161 gacaaagtcc ttagaatcgc ttttctaggg gctttttatg atatttagga gtataatata
     5221 agaaaaagga cttgtgaggt tctcctatgt tacacaaaga aaaacctgat tataaccgca
     5281 atcagtacgg tttctatacc cttgaccagt tagtgcctga tgaacatttc ctgcgccaag
     5341 tggaagctgt gattgacttc gacttcatct atgacctagt agaagacacc tattcgtctg
     5401 ataatggtcg ccctagcctt gatcctgtca tgttggttaa aatccctctg attcagtgct
     5461 tttatggcat tcgttccatg cgtcagacca tcaaggatat tgaagtgaat actgcctatc
     5521 gctggttttt aggtttgact ttggatgaca aggtgccaca tttcacaacc tatggcaaaa
     5581 attattcccg tcgctttcaa gaaaaaggct tgattgagtc catttttacg catattgttg
     5641 ggctatgtat caatacaggc ctgattgacc cgacggagat tttcatagat gggactcata
     5701 ttaaggctgc ggctaataat cgcaagttca tcaaccgaga ggtggaaaaa caagccaagt
     5761 tcatgagtga acagctagaa atcgaaatca atcgggatag ggagaagcat ggaaaaaagc
     5821 cgctagggcc cgccaaagag ctagagcccg tcgctaagaa aatctccaca accgatccag
     5881 aaagtggctg gtttcacaaa ggtgatcata aggaagtctt cgcttattct gctcaggtgg
     5941 cttgtgacaa gtatggatgg gcgcttgctt atagtgttga ggctggcaat atccatgata
     6001 gtcaggcttt tcctgcactt tttgccaagc ttgaaccctt gaaaccacag tttattattg
     6061 cggattccgg ctataacgtt cccagcattg ccaagtttct gattgataag gagatcactc
     6121 ctgtccttcc ttacacacga ccaagaggaa agaaagacct tctacgtccg aaagaattga
     6181 tttatgatga gcactttgat tgtgtcatct gccctgaaca tcaagccttg acctaccgca
     6241 ctacgaccag agaaggctac cgagaataca aaagtgaccc tgtaatttgt gccaattgtc
     6301 ccctgttatc tgtatgtacg accagtaaga actaccaaaa agttgtcaca cggcatattt
     6361 ggaaagacta tttggcacag ccaaggaata ccacaatctc tgctatacga gagagaaagg
     6421 caagtccaaa atggaagata cggttggact gactttggca tgcttaaatc tcaaaaaact
     6481 ggtcaaaagg atggcgggag agccttttta ttttgttcag atgaggtggt ttaagcacgg
     6541 aaacagccat ttttatctaa aaacactaaa aaagacaaac accaaatcga tgtttgtctt
     6601 caatctgttc tagagacttt ttctttattc tgagcgatag ttgtcataca ttgctttttt
     6661 agatgagtac actgcactct tttataatgg ttttagtgtc cgtggaataa agagttcagc
     6721 attatactca ctattgttaa cttcactatc actttattca atgtatcata gtctaaccaa
     6781 gcttgctagt ttccccaatg atagtcacca gcaattcagg tagtggcaat atgctacccg
     6841 tctcctaagc aagaatcttt ctcggactca gatagtccat agcgcagcgc atcaatcact
     6901 cctatcagaa attttagcaa gacataaata acattttaca gccctacatc acctatggaa
     6961 tcagaatttt tcgtaaaaat ccctaagaag cgtggcaaaa gcagcactaa actattccta
     7021 tcgcatccct ttacgttgct gatggtgtat atggtgtacc gaaggcttgc atgtaacctt
     7081 ttttatattc gtctgaccag ccaccatact ggaaaccttc aaaatcaata cctctacctg
     7141 agttttttgc tttcaagcca gctgaaaacc ctctatcaaa atctgattct tgtggatttt
     7201 tttgaggagt atgttgcggt ttttctgtca cacgaggttc acttgggaaa cgagaggtgt
     7261 cctcagattg gccccaatca gaggggccag atgataatcc atcaaagcca ttccactgag
     7321 gccactcaat ctgaggaggt tcaggaatat gagatgggtt tggtgattgt tcgttctcag
     7381 gtttaggaat atgtccaggt cctctccaat catcacgttt ttcataccct gtacctaatg
     7441 ctcctccata tggtggagtg taagggtcag ttgccaccgt accaggtcct ccccaatcat
     7501 cacgtttttc ataccctgta cctaatgctt ctccatatgg tggtctcgtt ttatcttctg
     7561 tctcatcttt tttatcgcta gaccagtcat cttcaggcca atcttcaggc cattcttctt
     7621 tatcgctaga ccagccatat ttagaccagc catattgaga caaaccaact ccagaccggt
     7681 catatttaga caaaccatct ccagaccagt catcttcagg ccagtcatct ccagaccagt
     7741 catctccaga ccagtcaaaa ttgcgtgatg tatacgtttc ggctgaaact ggttgtgtag
     7801 ctcctagtag agccacggct acaagggatg taaatagtag tgttttacta ttttcaatct
     7861 tatttctaat attcattagt attctctcct taataaatta tttcgttaat gttttcatta
     7921 taaaacaaag acgattatta gtaaaggtca gctttttaag agttgtttag tttgtgacct
     7981 ctccttaacc tcattcttct atacataaaa gagagaaccg actggttctc tcttgatgtt
     8041 cactcagtat tacaaagtga tagcttagtt ttcttctttg cgttttacaa ctgctgctac
     8101 tccagctgtt gccataacag taagggctgc cgctgtgaag aatgggttag ctgtttcacc
     8161 tgttgatggt aactgtctct tagtttcctt cattggtgct ttgttttggt taggttttgt
     8221 acctgcttgt ggtgcttgac ctttacctgg aacagctttg tttcctggtt ttgtatcagg
     8281 ggtttgtgag tctgatgctt ttccagctct tagttttgcg agttcttcag cttgtttcgc
     8341 taattgttct ttgagtgctt ttgcttctgc ttcaagtttt gcttgtagtt cagctttttc
     8401 tttttctgtt aatttcttgc tttcttcaag ctctttgtta agtttttcaa gagcagctaa
     8461 tttgctgttt gcttcttcta aagctttttc aacttgtttc ttagcttcac gtgatgcgtc
     8521 caagtcacgg cgaaggcctt gacggcttgc gtctgagatt tgtttttctt ctttaacctt
     8581 atcaagttca gcagtcaagt ttgctaaatc tttttcaacc tgtttcttag cttcacgtga
     8641 tgcgtccaag tcacggcgaa ggccttgacg gcttgcgtct gagatttgtt tgtcttcttt
     8701 aaccttatca agttcagcag tcaagtttgc taaatctttt tcaacctgtt tcttagcttc
     8761 acgtgatgcg tccaagtcac gacgaaggct ttgacgactt gcgtctgaga tttgtttttc
     8821 ttcctcaagt tttgcttttt cgatcgttag ctgctctttt tcagatgaaa gttgatcaag
     8881 ttcaagtttt gcattgccta aaagattacg attaatctct tgttctctag taatcgtttc
     8941 taactctttt tctaagacgt tagctctatt atagtcctga ctcgcttggt ctatcgctaa
     9001 ttcaagagct ttctttttct cttctaactc tttttctaaa gcggtagctc tatggtagtc
     9061 ccgacttgcc tggtctatcg ctaattcaag agcttccttt ttctcttcta actctttttc
     9121 aagtctttgt ctatcccaac ttgttgattc ctttgctaag tcatagtctt gttgtagttc
     9181 ttttaattta gtttctaaat ctttacgctg gtcttctaag gcttgttttg ctttttcaag
     9241 ttcttcagct ctcttaaaat ctcttcctgc aacttccatt gcattctcta atctcgcttt
     9301 taagtccttg ttttcgtgac gtaaacgtat attttgtatt gcgggattgt ttgctgcaag
     9361 atcttctata acttccctag gattaccatc accgttagcc ttaacctctg tttgattcgc
     9421 aaaacctgcc cctaaaacag tcaaagctac cgctactgaa gccgttcctg tttttaattt
     9481 tctaagcgaa tagtgtctat tcgtgttatt tttagccatt tttatgctcc ttatgctatc
     9541 attttttagg aagaaaccct cattttcagg gtttaactct aataattcta ttgtaaataa
     9601 taaaagccaa aaggtaaaga ccagcttttt tagcttttgc cacctttttg acctaaatgc
     9661 tattaatgat gaatctgttt ttgagttgct acagttaggc tgtctaagtt gtggaggggg
     9721 gggcatgcaa cttgttgggg ggagtgggta agataacctc tttgcgatga aagtccaagg
     9781 ggttgatggg tttgtctagt ggcaagctgt ctgcaaagct gatgtttaaa aacgcattga
     9841 gcttgtcaat aatcgcttct ggaatcattt tgtggaaaaa gaaaatttct agctcttcgc
     9901 tttttcctac cataacatct gtcacgatca catcatactg tttttcaatc tcttctagat
     9961 cgatggtcag agcatctagc tcattgaagt ttgtgatgct aaaaaactct ccgacgtact
    10021 tttttaggaa attaccaaca ctgttaaaac ttctttcaat caccagaaga cgaatttttt
    10081 catctttttg atttactttt aggaaactat tttcccaagt gatgaaaaag gcgtagatca
    10141 attggttagt caactctgtg ctgataggtt ctttctctga acgcatcagt ttttctacac
    10201 ctgctacaaa tgctttataa agatgagggt gttcttgctt gtaaaagttg aggtaacttt
    10261 ttttgtaatc gaaaaatagg taattagctg tgatatcttc ttctttcaat acggtagtgt
    10321 tatgaaggat gacagctact tcgtatttgt tggtgacgct gagattgagc ctgatttcta
    10381 actcatcaag gagatgaacc cagttggtca cttttcgaca gcccgttggt gagtcttgtt
    10441 tgatgctatc aaacgcataa ccgatttcta attggtcatt aacgtgatta gagaacatct
    10501 cagctatggt agtctcatct aggtatagtc caaatttgag gtgaaacaag cgtgaaaggt
    10561 cttggaattc taaggatgat tggatgagct gagaaaaacg ttgactggtt tttttgttgt
    10621 cgtagacggc agagtgtccc ttgtaataac gaatcaagtt aactgagctt agtattttaa
    10681 ggtgctgaaa taatgtaaaa ttaaccctca catcgacctc ttttatcatt aaactgagta
    10741 gccgctcaca gttctttaag tttaggattt ccccaaaagg ccactctgag attttatagg
    10801 cttccgaaaa atacttgagg taaaatagtc gaatctggtg ttcatctcct gatacttgta
    10861 cgggactagt taaaatagta ataccaaagg tatgcatcaa ataggcattg gtttttttga
    10921 tgagacgctt gagtgttgaa aggctcacaa agagctcttc agctaattct tccaaagagt
    10981 tgaagtctct gaaaaaaagg gtctccagca atttaaatga ttgagagtgt ctcagagctt
    11041 tctgatagac ttcttgcaaa ccgcaatgtt gatggtacca gattgtaata taaccatttt
    11101 tataggtaat tcctcccact tccttcataa attgcatgtt agtgagacat gtttgcaatg
    11161 ttaacatgga gatgttgaga gctttgctga gttctttatc tttgacgcca atggcgtcag
    11221 cgttttctgt tacgtatgag attaatttta gttctctcca ctgttgactt gtaaacaact
    11281 tacttacata cattaccttg tatacccttc tttttaattt tcttgatttt cttgttattt
    11341 cgtgaggtat ttcgttaagt cagtacgacc tatattaaga aaaagtatac cataaaatgc
    11401 ctttcaaatt ctttcattaa aatccaaaaa acagtcacga tcacgcattt atttcttttt
    11461 gttcattatt tataaaacat attataaaac gtgacccaaa aattggattt ttacccattt
    11521 tttatgccat ttatgctctt tttgttttaa aagaggtctt attttatatt ttttttatat
    11581 tttttgaacc taatttatct tttgtcacta acttaattag attttttaca tgcaattcaa
    11641 tgtttttgac tgatttcagt ttttaagttt gactgttatg gtacaaccat taaaaattct
    11701 atcatacttc agtcaattta caccaacatt agctcttgaa aacgtttcta cgatgttttt
    11761 tatgaactgg ttaacttgtc ttttttcgtt ggctattttg agaaaacagg gctttgggtt
    11821 ctattttgct tttaatttta gccatgtgac tctcacatca taaggagtgt ttggcttttt
    11881 gatgacatca tggctctcaa aagaccaaaa aacttccaat aacttagctc gtgctctaaa
    11941 ttattggaag attatttgac ctattactct aatctcgcaa attgtcctct aatgcgtcaa
    12001 agatacggtt tagagcaaag ataataaaga aacagacact tcctaacatg gcaacactcg
    12061 ctattcccat aaacgtattt tccatgctag gctggcccaa aagaccaatg ccataactga
    12121 gtatacttaa gagtaaacag gctgtaccta gttttaggag gtagccatta cgaacacgtt
    12181 tttttgtttt ttgactcggg gtggtcactt tctttatcat ctgatgaacc tcattctaag
    12241 ttgacgctgt ctctttttga gattggtcaa caggcaggta gcttcttggt tgtgggggtt
    12301 atggtcttgg gagtttgtcc cctacgacat aggtcaacaa actagcctgc tcagctgtga
    12361 acgtccgata ggaaatggtg cctagtccca taacatttga ctctgaaatt aagatagaac
    12421 catcttcttt gatttgctct acaacagcaa cgtgaccata ggttgcatct gctcctgctt
    12481 ggcctggtgc aaatgagacg acatagccca ctttaggttt atgggtggtc acaaaacctg
    12541 gcttgcgctg ccagtcgcca ccgttaccca tgtacctgtc gacttgataa cctagctctt
    12601 tgacacgatt ataggcgtac caagtgcatt ggccaaagct gtaggtctct gacttgtagg
    12661 tcaaaacgtt ttgtggctga cttcttttat aacctacggg cacttcgcta aattgtgtcc
    12721 cggaagttat cttgagatgt tctggaatct caggtgtgct tccatgatca tctatccatt
    12781 ggtctagttt ggtcatgata tctgctcgtc tttgcccact gccacttgta tctgtaaagt
    12841 aaaccccacc atcaatcaag gtatccaact ggcctagtga ccattttttt gctttgaggt
    12901 cttgtctttc aaaggtttgg tttttgttgg caatgatggt gtcttctacc atgtgacgaa
    12961 tagcaacctc atcgctgtat tttttggcat tgtttgggtt gaagtcaaag gcgccataac
    13021 caaacatatt ggctcctttt tctttagcaa ctccctgagt acctagtgag ctttctgcca
    13081 ttgcaatagc tacgatagct cgaacgtcta gtcctgttag tttttcccat tctaataaac
    13141 gctttccgtt taagcgttct ttatcatagt gaatacctag actgttcaaa aaaccatcta
    13201 gctgttcagc agtaatccca taacggcgtg acaacaggtt gtgagtgtag gcagagtcac
    13261 ctgtccagtg tctcacgtaa gccgctgatg agcgactgct tggttttagc ttgctcaggt
    13321 ctttgtcact ttctctccaa ggtataaaga caggagcagc tgctaaagga ggttggatgg
    13381 gttttggagc gtcacgattt ggctctggtg ttttatcagt tgctttttct ggtccttttt
    13441 caggtgtttt atcaggtgtc tgatcttttt gctgatcagg tgatggggta ggtcggccgt
    13501 ctttgttttg tgactctttt tgagacgact ggtctttggg agatggggtg gattgatcac
    13561 tgctgtctgg ttgcttggtg tcgtttttgt ctttatttgg tttgtcagta gcttcagatg
    13621 atgcctgatc ggtctgctta gtatcatttg aagggggggt tgggtgagtg tgtgatggct
    13681 tatggtcttt ttgggtgtcg tgctgcgacg ctgtttcctt gctttttttg tctttttttg
    13741 gtgtttcact ctcgtcatcc gtatcagtat ctgctgtagt aggctgatca gtggatgatg
    13801 tgctattacg caaggaggta tcagcaacaa ctaatggcac tgcactgttt aagagtatgg
    13861 tacttaatag tgttactgct aacaatttcc ttttcttcat atatgatttc tctcctcttt
    13921 tttatacttg cctaaacaat gatgggtaaa ggtcaaggct tggttaatga ttgatgactt
    13981 ttgtcgtcct actagtatgg atcaatcgtc atgatgggat ggaaaatcaa tcgtaaatac
    14041 catccatctt tgatcaagaa caacaaagcg ataagccaga tgatgctgat caagaatctg
    14101 gtgggtgata aacagcccca atcctgtacc accgtctttc ctgttacgac tataatctgg
    14161 tcgataaaac ggttggaata actgtttcat ctgctgttgt gtcaataatg tctctgcttc
    14221 atttttaatc actagttggt tgtcttttag ttgaatcatc acttggccgc ctgatttggt
    14281 atagtgaaag gcattgtcaa taatattttt aatcgccttt agtagatata ctttattggc
    14341 tttgacgaat tgttcttcaa gattgatagt cactttgagg tgttttagtt ctgataagac
    14401 gagaaagact tccatttctt cttctaggct gctttttagt gaaaacagtt cttgattttg
    14461 agaagctagg gtttcaatct tagataaaga taaaatggat tgaaccagtt gggcttgccc
    14521 ttcaaggacg tctcggcact ttcgcaaata tttgtcacga tctgcaaagt caccaacatt
    14581 atagagcatt ccatcaatca ttccgataac actagtgatt ggtgtcttta gctcgtgcga
    14641 tgtcatgcgt aaaaactcag atttctctct ttctgaatca gaagcttttt catactcttt
    14701 ttgcaaggat ttgatgctcg ttgaaagact cgcatacaaa cggttaatat cactagccaa
    14761 cattgctatt tcatctttgc cgtgaatggt acacgttaag tttggttcta ggttgaccat
    14821 ttttttggcg gtttgtgaca tgctaaggat acgccggcta gaagtcctac tatataagta
    14881 ggcgacaata ctccctacgg tcactgaaaa aatcaatagt gacgggtaga ggtcaaggag
    14941 aactttgcta gcatctgtta cgggttgaag tgaagattgc ccaagcaatg tcattttttt
    15001 tccatcgcgt agggttactt tttgactcat caccttaaca ttagaataag agttgtcaaa
    15061 ggtggtgacg atattaacat tttgactgtc tttgctttca ctgacgccgt ctaggagctg
    15121 caaggaagga tagagcagtt ggttatcact gtctactaag ctgtaccaaa tattatcttt
    15181 gttgattttt tttgttagga tatctctaat ctcggttacc gttttgcctt tgatttgctt
    15241 gcttgtttgg tcaaattcac acttaacttc tttgtctttg actttggtgt aataaattgg
    15301 cattgcaaaa taaagcacta acaaaataga ggtaaccact acaataatta agccattgat
    15361 gaccaaaaag gtttttttga ttagtctcac tcacgctctc ccaataaata gcccatgcct
    15421 gtaattgtct tgaggggaat acccgtcatt tttttacgaa ggttcttgat gtggttgtca
    15481 aggacacgcg tgtccagttc agaatagccc catatgtcat ccatcaattg gtctctggtg
    15541 acaatttttt ggtgacgttt tgctaaataa tcaataatgt catattcttt tttggttagt
    15601 ttgaccaatg ttccttgcca atagacgcta tgttcggtct catcaacaag taagtctccg
    15661 atttggcgct tttcatctgg agtagagacg cgtaatacat tttcgatacg tttgattaaa
    15721 atgagtggtg aaaatggttt ggtcacataa tcactaatca aatggttgaa gcttacaagc
    15781 tgtgtgtact cgtcatctaa tgccgttagc ataataatag ggacatctga tgtctttcga
    15841 attgttttta gcacttctaa gccacttaag gaagggagca tgatgtctaa aataatcaga
    15901 tcataagacg ttgtctgcca cttgtctaag gcagcttggc catcaaatac acaatctgga
    15961 tcatagttat tcgcttttaa aaactcacaa atcacttgac tgatggtatc atcatcttca
    16021 actactaata ttttaaacat aacttccctt tctagattgg cgtttagtgt atcaagcagc
    16081 taaggatgac atcaaagggt catccttttt gacttttatg cttgtttggt tgattattca
    16141 aatcgcaatg cttcaattgg gtctagctta gacgctttaa tggctggtaa tagtccaaag
    16201 acaatcccta taatacaaca aaacgctaaa ctcaagacaa ctgagaacaa ggataggata
    16261 tagggatatt cgagtgatct tgtgatgatc aatcctgata ccatccctga aataacccct
    16321 atcacaccac ctagcaaggt tagaatgacc gcttcaatta aaaattgttt taaaataagc
    16381 ttacgtctag cgccaagcgc ttttttgatc ccaatttctc tcgttctttc ggtaactgat
    16441 actagcataa tgttcatcac accaatacca cctacaataa gagagatact agcaatacca
    16501 gctaataaca caaaattaga tttgtttagg ttgtctagtt ggcgttcaaa ttctttaagg
    16561 ttcatgacac caaacatata atctgattta gggatcgttt gattgagcat atcactgaca
    16621 cgctttgcta caggtttgag gtcatctgcg cgataggtct ggatcgtgat ctcaggtgtc
    16681 gcatccacta caccattaat attataccac tgatgtagcg ggatataagc aattttctca
    16741 gtcccacttg tgaggccact ttgttctttt gattcaaaca ccccaatgac cctgaaggga
    16801 tttcccatca cttcgacaaa ttttccaagg ccatcgtctt ttggaaatag tgactcatac
    16861 aagctttttt caaggtaaat cacctgtttt tggtcaataa agtctttgtc tgaaaagtca
    16921 ctgcctttaa taaatgtcat gcgtctcact tcagctacgt tttttgtgat ggcagaaatc
    16981 tttgcagatg atttttggcc tagatggtag actttgtcat caataccata tgagatcagg
    17041 gcatttttga cgcctttgac ttgctgtatt ttgctaagct cttcttcagc cataaaagga
    17101 agatagtctg gttttttagc atttgacttg tctggaaatt tagggtcaat actacttttt
    17161 ttgttaaaca caatgttaat agtgttattg ctgccaccaa tcaactgtct tttggtattt
    17221 tcggtattac cttcgatgat tgaaaagatt gcgataatgg caccaatacc gataataatc
    17281 cctagcattg tcaaaattga ccgcatcttg tgtgataata tagagcttaa agctgcaata
    17341 atatcttcca ttattttccc cctttactct atatcggaat gttctatatt accatctctt
    17401 aggatcaccg tctttttgca tagggcagct acttcaggct cgtgtgtgat gataataatc
    17461 gttttgccgt tatcattgaa ttgtttaaat aggtccatga tttggacgct ggtttttgtg
    17521 tctagtgcac ctgttggctc atcaccaagg ataaaactcg ggttagtgac taaagctctt
    17581 gcaatcgcta cacgctgttt ttgcccacca gatagctcca tcggtttaaa ttcactacgt
    17641 tcttctagtc ctactagctt taacatctct agggctcgtt tgcgacgctc ttttttagga
    17701 acattcatat aagtcaaggg taattcgaca ttttgacaag ctgttagctt gggcatcagg
    17761 ttaaaatttt gaaaaacaaa gccgattttt tgattacgca aatcagcaag ttcattatca
    17821 gataaggatg acacgtctct gccttcaatg gcatatgagc cagagccagg cttatctaaa
    17881 cacccaatga tattcatcaa tgttgacttt cccgaacctg atggtcccat gatggctaaa
    17941 aagtcaccct cgttaacttc taaatcgatt ccttttaaaa tcgcaaattc ttcagttcca
    18001 agatgatagc tttttcgaat atctttaagg tttaacaata cttcctacct ccataccgtc
    18061 tttcatgcca ggaagcggct gagcaatctt atcttgcata gtcaagccac ttgttacctc
    18121 aacataacct tttgagaagg gcttagtctt gatttcttgt tttttgacct tgtttttatc
    18181 aactttccac acataggttt ttccattttc tgccattgta aaggtttctt tcaatacgat
    18241 cttgccagct tctggaacat tgttgagcac attaacatag gtgtgtgagc caatgagtgg
    18301 ctgcttgtct gattggtcaa gttcaataac ataagggaat tttgcttggt ttggattatc
    18361 ttgttggtca ttgccacctt ggccttgacc ttggcctttt tcctctgctt tgaggttgcc
    18421 aacttgggtt acttttccag tccatttttt agagttgtct ttgcggtcaa tcacttcgac
    18481 tttttgaccg atttttaact tgtcacggtc aaattcacta atgttacctt tgactaacat
    18541 ttttgatttg tcgataattt ccataaaagt ttcattttct tttttggatt ttgattgatt
    18601 tggcaaatca gtatttagac taacaatggt tcctgcggtg tctgacttaa cggtgtcata
    18661 ctctagttta cctttttccg ttgtggcagt agcattagct ttatcgagtt cgatttgagc
    18721 ggttttgaca tcgctatctg ctgttttggc atcgcttagt gcttgggata cactgtcttc
    18781 tgcgctgcga atttgctcta gtaagctctc atctggtgca gtgttgtagc gagattttag
    18841 ggtgttgatt tcattgacct tgcgattgta ggtttcccac ttcaatgctg cattggtttt
    18901 agcaacttgg agctgattgg ctttggtttg aacatcaaat tctgaacttt gagccgttaa
    18961 ccgctgtgac gtttcatagc taaacaaggg ttgtcctact ttgacaacat cgcctttttt
    19021 aacaaagacc tctttgactt ctcctttact tgagtcgatt ttgactttgc tgctgttgtt
    19081 agctgttact tcgccagcta aggtcaagct gatatctttt ccttgttcca tggcttcttt
    19141 tatggttaag gcttttactt tgttgacact agagacaatt tcttgttgtt gatggttcat
    19201 tatcaagtag ctaccaccaa ccacacaggt caacactcca gcactcaaca aggctaattg
    19261 tttgcgcgtc attttttttc ttaactgaaa catactttct cctcaatagc tattttttct
    19321 ttttatacga tttttatggt tataccatac caacgttatc ccttttgaac ggtcactagc
    19381 aagacctact agtcatgatg acgcttaaca ccaacgatta atccgatgac caacagtaag
    19441 atgacaggta taatggatct tttttcattt tagcacttcc tttttggtag cttgaaacac
    19501 gacaaactgg ctattttagc gttcttttct tgtttttgga aaacaaaaat catataaccg
    19561 ttcgctcaca taagcacggg tatatgattt tgtacatttg cgagttagtg tgtttggcta
    19621 tttaggcatt atgataagtg agttaccatc ttaggcagac tgcctcatgt catgcgtaac
    19681 gtttgcgagt caccttatgc tctttgttgt aacccttagt ttttagcagg agcgcctgat
    19741 ccaccagcat cttttgattc catgccttct tcgtttcctg caggaatctg aatcacgttt
    19801 ccatcttttg tggtgtattc tgtaacttct tcgccatcaa ccacttttgt ttttttgcta
    19861 actgcgtcgt ctttgatgtc agacattttg atttctttaa cttcttcttt tttagaatct
    19921 ttttttgtgc cacaagctgt taaaaagcat gttgctgcta atgctaatgc aggaatgact
    19981 aatacttttt tgaatttcat gatgaaatgc tccttttgtt ttgatacctt tagtttaaca
    20041 gacgcatcta ctgtttttct aacgattatc tgttttttat ctgttttttt gagattggct
    20101 agcttttttt gtcctgtcat cgtagtatct gtgacgttag cgatggttac atatgcttgt
    20161 acatgatagg ggccaagtct aagatatcag ctagtagttg gttatggtca ccgatcatat
    20221 caaagaggag gtcttcagat aggacaccgc acgggatatc atcccaaggt tggtttgcaa
    20281 gccgaaacca ttcgtcacta ctgtaaaaat ttctaagtgt ggcatattcc tcataatgct
    20341 ctttaaaggc atctagggct tctatgagat ttgctagctt tgggctaaag gcctcatagg
    20401 tttgttccat tttttcaacg attaactgat cttgctttgt catgggttgc tcctttgctg
    20461 gttattacct ttattttaca ccgaaatgct agcaattgtc atgaaaaaac ctctatttga
    20521 taaaagcata catcatccaa aaaatgtgct cactcaataa atatagggtc atcattttta
    20581 tttaaagatt gttttgtgac cttgattttt aatctttttc tccttaaaat gacattattg
    20641 acactcttgt ctgttaaggt gactatcatt agataaggag gccaagatga cccatcgttt
    20701 ttttctcacc cctctttcaa ccctctggcg ccgtctgaga ccaaagcgtt actccaaaaa
    20761 agttttggct gatgagccta ctagctatca gccaccggca gctcatggcc cgtgcgacga
    20821 tattcatcag ttgcttgagg acaagagctt atcagacgat tatctgattg ctacttctgc
    20881 gatgagacac ctctggtact gggggtatag tcagattggg tagttagagt ttctgactcc
    20941 caatcagcta tgttaacgga ctatcactga taacattcac gctaagcctc attctagcta
    21001 ggcttagcgt gaattttttt gctgactggt ttttaaatat taaagactct atccttattt
    21061 ggatagagtc tttagcttta tgacattgcc ctagaccatc agtataggac acgtttccat
    21121 tatcggtgtt ttgaaaaggg gagtgatggc tagggctgtc tttttaagca accttaggga
    21181 aataaactgg caaccctcta tttttgggca ggttgttttt ggttaggttt tgcaaactgg
    21241 gctaagatat tggcaaatgc tttgtctttg attttgacat ttgctttatc aagagcttta
    21301 gcgatgactt tgttttggaa gtcagggtct tttaatttgc cagtcacgat gatgtctttc
    21361 aagcgttttt ggtacgcttt ccagtctgct tttttagttg cttttttggt gactttgatg
    21421 atatggtagg tgcgttttga ggtggctgga tcaagcgctg tgatgatttc tgatctgttc
    21481 ccttctttga ggcctgatgc agctctaact acttctgctg gtagggttgt ttcgcctgag
    21541 tcaaacgtat aggttgtttt tttatcggct gcagtggttt tttctttggc aatagctgca
    21601 aagtctgccc cttcagcttt gacggcttca agcgctgctt tggcatcctc ttctttttca
    21661 aactgcatga tttctgcggt catggttggg gtataagcgt cataggcctg acggtagtct
    21721 ttttttgaga tggtttcgtt tttggcttgt tctttgacgg catattcgac taattttgtg
    21781 aggcgaattt gttttttata ggtttctggc gttaagcctg attgtgctag gactgtctta
    21841 aaggatgtac cgtattggtc tgcggtttgt ttataggctt tttcaacctc tttgtcagag
    21901 actttgttgg catattgtgt ctcaaaaacg cggctaatca ccaagcttaa catggctttt
    21961 tgtgcgagtt ctgtgttttt ggtctcattg tagaagtcac tgacagtgat ggtgtctcct
    22021 ttcatcgaga cgagtttggt gttgttgtgt gatgattgac aagctgataa ggtcacgact
    22081 gtcgccagcg ttaccactcc tgtaatgagt ttattcattt gtttcatgtc cttttgagcc
    22141 tcttttctca ttaataatta ctgttatctt atatcattag tcttaaacgt agcttaatct
    22201 tgctttttgg tgttgctgct cgttgtgact gttcgttaga aagccactgt ctttaggata
    22261 ggttaggttg tggtgtttgg ctgtagtcat gtatgaacag aatctgacgt tggctatttt
    22321 tgagtgttgt tttcttgcca cggtatggct agaataactc tcaaaaatcg taaaaggact
    22381 gagtcccatc tctacagaac tcagtccttt accttggcat cttagggaag tcatcattag
    22441 taggcgttga tgacctcctt tatcaatggg tgacttttcg atggaaacag tctgctccat
    22501 gagacaaaca cttgcttagg tcggcgtgaa acttaaaagg tagtggtatt ttagaaacac
    22561 ggtcgtctta aacgagtggt gagggggcaa aagctacttt gaccgatcaa tccaaagagt
    22621 tgatttgttt ttggtaagct tctatcatac tcctgacatt atcatggttg aggtctaggt
    22681 tattatcaaa agaatagcct aaaatggtgt gcgctctggt gtctcctgat acgatgataa
    22741 atccagcagg agacaaagca tagatgtata gctcaccacc tgagtgatct gtgtctgatg
    22801 gatagcttaa ctgctgcacg cgcatagggg tttttgtttg tgtgttttcg gcacaaaagg
    22861 tttcagctat gcggcgtgcc tcaggttctg ttctaacgaa atgcatttcc atactaaggt
    22921 ttgatgccta caacagcact ttggtaaccg ttgaagccgc ctgcgccgcc accagtacca
    22981 agagctgaag ggtttagtgc gtcaagacgg aagaagccgt cagagactcc accccaaccc
    23041 cagttaacat ggtagaagtt acgtccgtca gcaccatcga taacaaaggc atgtccgcct
    23101 actttaccga caccttggta gtatactggt tggttttgag ataattcttt gtcaatttgt
    23161 gcttcccaat cttgtttgct aaagtcgcca cggttgattt ggtgaacaga ttggttgtag
    23221 ccaaagtttt ctttcaaggc tctttgaaca cgagagctac ctgcagaacc actagatgga
    23281 ccataatcca tgtctactga aataccaaca tcagccatca attctgaaat cgccattttt
    23341 tgaacgttag attctcttcc gctataagta ggtaagatgt tgttccagtt gtattgtcta
    23401 gtagagatag ctgcaaacaa gttcttagga tggttgaaat atgggttatt tgagcttagt
    23461 gtgtaagtgt agtctttcaa ccctttgtta gggtaattat gatatttcat aatttgagca
    23521 gttgcagtag caacacatcc tgtagctgca tgttgaccta caaaagattg ttcacctggt
    23581 tttacttttt caataacagg tgtcaatagg ttgtaagggt taccttgatt gtaatgaatg
    23641 ccttttgaat caaggagaga tttaacaact ggttgtttaa tctcagcggt accagcataa
    23701 gtagtgtcta attttttgtt ttctttgatt tgttcgacat aactttccat gaaggaagca
    23761 atgttttctt taccgttagc gtcaaatgat ccgctggtag agtatcctag aatttctgga
    23821 gaacgtttat ctcctgaaac gataacaaat cctccagtag aaatattgta aacatacata
    23881 ttagagccag aaagttctcc acctaagtta actttgtcaa gcttaatatc ttctgcgctt
    23941 cgtgcacctg ctttgatagc tgctgatttt tggataaatg tgatagcgct atcttttgct
    24001 tctttttcgt tacgagcaaa gttttgatcg gcaaatactg ggttagcaag aacaaatcca
    24061 cctaatgcta aaagacttaa taatctgaca cctaatttct ttttattcat tttttttata
    24121 cctctttcaa aataagttaa tctactgcat ttgcttttaa cggtacattg gacacacctc
    24181 cttacttagc tgaatcgtat ggttatcata cgatgtcgct gataccatga atggtaatag
    24241 acaataacac ggttagttga cactgacaac ccaacccaat tattctcatc tcatgtgagc
    24301 ctaattggtt ttggtcaaaa gacgctatga gtcgttgcac ttatcatctt ttggttgatc
    24361 tcttatcttc tgccgtatct actaggcaga ctgataggca agatcagcta gcaaacaata
    24421 ggttgtgctt gacagttttt tagatgatat gggaccgttc tcattttgtt aataactgat
    24481 tctgtgataa ggatcgtgat agggtccaca acaccaagtg aaagtccttt gtcttttttt
    24541 gggttgtcca ttagttgact cgtaggcttt ttcctggctg atttatctca tttttactga
    24601 caattagcct tttagttact attgtggcta gtagatgctc atttcagttg acaagaaact
    24661 taaaaatact gataatataa acaaaatgat tcttttgttt gtcaatgctt ttattgactt
    24721 ctcattttta tctactacca ttttgcaaaa ggaactacaa aaatagtaac aataaccaca
    24781 tagtaggcgc ctccttttaa ccttatggct atatcatagc tgcttatttt gctaacccat
    24841 tattttgtta cgtattaggt acacacgtaa cgtattttta acatctatta gattagaaag
    24901 gtttaacata tgacagttga taaaactatc gcatctggct attgacctta tgcacctatc
    24961 ataagcgact atcatccgaa acattcaact tgttacgtat taggtacatg cgtaacgtat
    25021 ttttgacatc aactaggaag gcttgacata tggaaattgg tgaaaccgtt gaattcatta
    25081 ggcattcaaa aaacatttcg attaaacaag tttgtggtga ttatctcact aggcaaacct
    25141 attatcgttt tattaaaaat aatcttgaca tttcttcgaa aaagttactt tatatcttag
    25201 acaacttgaa tgtcaatgtt gatgagtttc tctttattag taataacttt aaacaataca
    25261 aagaatttat tgatatggat acggcaaaac attattttga atgccgaaac atagaaggtt
    25321 taaatcatat ccttgattct tataaagata gtaagtcaac aaaggaaaag aacctttttg
    25381 ccttggtcaa ggtgttatta gcaactctta ctgaggaaga ctgtctgaca gagcggactt
    25441 atttgtcaaa ctatcttatt aatattgaaa cttggagtca ctatgagact gtgcttttta
    25501 ataattgtat gtttattttt gagtcttgct ttattgagat ggtgttttca aaagttattt
    25561 tgaacctcga taaatacaat accctaaggt attatgggaa tgaatcgatt cggatgtttg
    25621 tcaatatgtt gattttgttt attcagcgac aagagtatga taaagcttct gagattttgg
    25681 caaaaattga agattatcag ctaaatgatg attgcttata tgaacggtgt tgtgtgtctt
    25741 tttttgatgg cattattggc ctcataaatg gtaaagaggg ggctgagcaa aagtgtgtgc
    25801 agatcttgga gatcttccaa ttacttaatt gcaaaacgat ccatcatatg tttcaaacct
    25861 acctagaagc cattaaacat aaactgtcct gaggctcttt aaaaagctaa cgctcttatg
    25921 gtgttagctt tttgatttgg tatcttaata aatggtgtag tttatctcaa cagctccagg
    25981 gcgatttttt caatttgctt tttacttttt gacaaatcat aaaaagcaat gacgacaatc
    26041 attgcttttt ctagtatttt tactttctat agtcattgct ttttttgatg taaaaagcta
    26101 ggcctagtga gcagaggtct agccttttgg tattatttct gagtaggtgt accgttatgg
    26161 tagttaatgg tgtagccatt agctgtgttg taaactaata ctttctcgtt gatggtatta
    26221 tcagaagatt gcattgatac cacgacagct cttggaatca actcgtctgc gttatagatt
    26281 ggagcagctt cataataaag atagccatca cgatttgctt ctaaccattc ttgagctctt
    26341 tgttcggtat agcgcatgcc gcctttttgg tcacgacctc ctacattttg ggtacgtgtc
    26401 cctgtaacgg cattgactct gagtgcatct ccaccgagac tatctgcaat gagatgactt
    26461 ctattccaga aatctccgac ataagataga ccatttaacc attcaatttt atatttgaca
    26521 tgattagggt ttccagtcca gcctgcgggg ttttgatttt taccgaaaga ttgtctaaca
    26581 ccgtagctac cttcaacatt ggcataagtc aatgtacctc tagcagtacg cgtccttcct
    26641 aactcatcta atttgctata gagaatatct cctgctttag gaaagagtgc tggagtgatc
    26701 tgactagtac ctaaggtttt gtaatagttg ggactgtcat tgaatgtcca agctaatgct
    26761 tcgtttaggt acttgcttgc gccatcattt agaacaacat catttgagac ctgtgtttgt
    26821 cgtgccagtg cagtattttc aagtgtgact gttgttacag ccattgtggc tgatacaaga
    26881 gctaccattg aaaattttac tagccgacat tttttagaaa aaacccgtct tgatccaagt
    26941 agattcatat gcttgtcctc ttttctaatt tcgctcacta accatagtat acgcttactt
    27001 aactagttta tcaatagttt ttttaaaaaa tatgaaaatt aaaggagata gtaaggagaa
    27061 aaaagaaggc gttgtctttt tgttttgcca tactaatatc atttttgaaa taggtgctgt
    27121 gtgtcaccta gaggtggtga ttgtatttag gcctaggtaa gatggttact ttactatcgt
    27181 ttctttgact tttaccaagt aggggatttc agtagtcaac acctcttaaa aaagaactat
    27241 tccctcttta gctgttgtag aggtttctta aaatctttta tgttacaata aagaaaaaaa
    27301 ggaggtttca catgtcaact gaccatcaat tacgagaagt ttcttatcaa ttactggctg
    27361 agcgaggggt ttctttagaa gctattgcag agctggtgct ttttttgcag aatgattata
    27421 ttcccaattt gaccatggca gaatgtttag agagcgttga ggcggtgctt gcaaaacgag
    27481 aagtgcaaaa tgctattatc actggggtag aattggataa attggctgaa gccaaccagc
    27541 tgtctgagcc actccttagt atcttgaaaa ccgaccaagg gctgtatggg attgatgaaa
    27601 tcctggcctt atccattgtt aacctctatg ggtctatcgg ttttaccaat tatgggtatc
    27661 tggacaagac aaaaccggga atagttgaca aactcaacca caaagatggc tactcctgcc
    27721 ataccttttt agatgatatt gttagcgcca ttgcggcagc agctgccagt cgtattgccc
    27781 acaatgaccc cgctaaaagt gctattacca accaacaata agcaaaacaa gtctaggaag
    27841 tgactcccta gacttgtttt tttgaggtta tctggcaaat aagaaatctc tttttggtta
    27901 gcctatcgac tcgtaacata ggcatcaaca gcaaccaaag ccgctgctac atcttctgga
    27961 ctgataacaa atggcatttg atggatggtt tcgcctgcca tggttgcttg acggccaatt
    28021 tttaagaaat cctcttgagt agccgtgtct aaatgcattt ctttgagggt tgttggcatg
    28081 ccaatagctt ggtaaaagtc gatgtagcgg tcaatttctt cacgcgaacg attttccaag
    28141 aagagttggg tcaacgtgcc ataggcgact ttttcaccat gggtaaggtg atgaatagca
    28201 cctgtcagcg ctgtaaagcc attgtgaatg gcatgtgcag cagccagacc cgcactttca
    28261 aaaccaagcc cactaagaag tgtattggct tcaatgacat tttccaaggc cggggtcacg
    28321 acttgtctgt cacagctagc catcgctttt aggccatctg caaacaaggt ctgctcacag
    28381 gctttggcaa tggcaactcc tgccaaggtt tgattgccac ctgccatggt gtctccattt
    28441 ttttgcataa cagcacgcgc ctctacccat gttgctaacc catctgcaat ccctgacgcc
    28501 aataagcgtt ttggtgcctg acagatcact tgtgtgtcaa ccaatacaag atctggattc
    28561 tttgaataga aaatgtattt ttcaaaggct ccttcatcgg tgtaaataac cgataaggct
    28621 gaggttgggg catctgttga agcaatggtt ggggcaataa tcaccggaac agcaagtaag
    28681 tcagcgatag ccttagcact gtcaatggtt tttccaccac caagtccaat aataacatca
    28741 ttgccatttt ccttggcaat ggcaaccacg cggctgattt cattatctga ggcttcgcca
    28801 ttaaaggcta cgtgaacagg agtcatgcca ttatctatca aatagctttc aaatctttct
    28861 ccgacgatgc catacaccac gtcatcacac agtaaaatgg ggctatcccc tagttgtttt
    28921 agggttttaa cattggtaaa caaggcattt ttaccttgaa tgtaacgaga tggacttgca
    28981 aatactttca tcgttgaact cctttatctg tgattcctaa tgatgtgatt actactgatg
    29041 ctatttctta aatgctcttg cggtgatgaa cggcttccca atccttgcca aaatcgtcaa
    29101 ccgctttttg aatagatggc atggcaaatc ctgcttcaaa cacatctggg ccagcagtga
    29161 tggcttgtgc tcctagagca aaggatttat taacctgagc cacattttta aagcttgctg
    29221 ccaaaatctt actattagca ttctcgcggt taatagcttc tgctaattgt tctatgacag
    29281 cttctggatc aatattaaga ttttccatac ggttatagta aggagccaaa taatcagcgc
    29341 cagcttcaat ggctaatagt ccttggaagg tcgtataaat agcggttgct gtgatgtgat
    29401 agccttcggc tttcaaggtt ttaatggctg caaggccctc tgtggttaca ggtactttga
    29461 catacacact atctccacat tgcctgcgga tttcagcagc atcttttaag atgccttcgt
    29521 aatcttgggc gatcacttga acatgaatag aagccttgtc accgataata gcacggactt
    29581 ctcgaatccg ttcaaagaaa tcaatctcac cttctttttt ggcaatagaa gggtttgagg
    29641 tcacacctgc gagaggcaaa atgtgatgcc attttttaat agcttctaaa tctaaagtgt
    29701 ctaacatgta ttccatactt attttctcct aaagtgtgtg ttctgtacgt tcaataatgt
    29761 catcttgggt tgcttttgag agcacattga agaaagctga gtagccggca acacggacaa
    29821 tgaggtcgcg gtgcttttca ggatgttttt gggcatcaat caaggtttca cgtgacacga
    29881 cattgtactg gatatgataa ccgtgtaggc gattaaagaa ggtacgaagt aaggccatta
    29941 atttcagttt gtcttcttct ttggccaggg tttgtgggtt aactttttgg ttgagtagca
    30001 ctcctccgac aatctcatct gttggtaatt tagcaacaga tttcaatact gaagtcgggc
    30061 cttttttgtc catgctgtgt tctggtgaac agccttctgc tagtggtgtg cctgcatggc
    30121 gaccgtctgg tgtcgccaag gtcccttttc cttgtccgac attggctgag attgatgatg
    30181 tcccagaata gcggatacct ccgattgggc cacggccata ccgggtattt gggtatttgg
    30241 caatttcatc aatgtaggtg tcgtaagctt cgacgactaa actatctgcg tagtcatcat
    30301 cattaccata ttttggtgcg tcattgatga gcatttggcg gatgtcttct ccgcgttctc
    30361 cagcaaagtc actttcaagg gccttccaga gttcctctgg ggtcaagcga ccttcttcaa
    30421 acactaattt tttcagcgct gctagggagt ctgataggtt ggcaatacca acttgaaggc
    30481 ctgagatata gtcgtaaaca gctccgcctt cttttaaggt cttgccacga ccgatacaat
    30541 catctgtcaa ggctgagcaa agaatatctg gtacttcacg ttcaagaccg aggtcaatgg
    30601 cattttcaac aatgacgctc atgcgggtaa tttcgcgcag ggtggcatcc catgctgctt
    30661 ttaattcttc ataagaggtc atgtctttga agtgaccgtg tccttttgca aagcgcttgc
    30721 ctgatgctgg gtcaatcccg tcattcatgg taatcagcaa gattttaggg aagttgatgt
    30781 aactcatccc cgtgcaacgg tagccccatt ttccaggaac tgctgtttcc acacagccaa
    30841 tggctgagta atcataagca tcttcttctg agacaccttt tttgatgaaa gatggaatga
    30901 tgatttcatc gttgttcatg gctggcatac caaaaccaag tttcatgacc tcgatacatt
    30961 cgttcataaa ggtattgtct aggcctttgt ggtaacgaac agtcaagtta ggttgtggca
    31021 atttggtttg agccacactc cgtaggacaa ggtaagacag tgggttgacc gcatcttttt
    31081 tatcgcgtgt ttgaccgccg attgtcacgt tttggtaaag tggactacct gctgatgaga
    31141 aggtgtgggc ttggctccgt actttattaa tggtcaaggt cttaatccag aggttggtca
    31201 aacgttcaac aattgtgtct tctgtttcac ggccagcctc caaatcagct ttgacataag
    31261 gatacatgta ctggtcaaag cggccataag atagggaatg cccatttgat tcaatttgca
    31321 aaatacactg aatgaaccag acagattgca cagcctctgc aaaggttttc gctggttcgt
    31381 aaggtacttt atcacaaatg cgcgcgatgt ctaacaattc tgcttgacgt tctggtttag
    31441 ccgtttttgc tagttctcta gccaacttgg catagcgttt agcataagtt ttgactgcat
    31501 caatgacaat aaaaacagag tcgtaaaaat ggtatttgtc aatgttttca ggaatggtca
    31561 aatcaagcgc agctttggca gctcgtgccc gttcttcaaa tccctttaag ccatgctcca
    31621 agagtttttg gtaattaacc gctaaatgag catccccaga gttcatcttg ccttccatgc
    31681 caaagaaacc tgtttccatg tacacttgca cttcttctgg tagcaagaca ccgcagcgag
    31741 cacgcaggtt attgttttcc cagaatgggg caatgtctcg gagctgttgc ttggtttctt
    31801 cggtaatgta gaagacatcc ccatctcgtt tttcaaaaag atcaagttcg ttgaggacaa
    31861 attccagagt gtattctggg aaaatcggtg catccttgtt tgaagaggct tggttaccag
    31921 caatgaggct ttcatcctca atatagatgg tcatgttttc caaaatagtt tgaagcatgt
    31981 aagcgcgttt gaggtttgct ggcttatttt ggtgtttttg ataggcttca gtggctaaaa
    32041 tagcacgctc agcatcaata taaggtttct tgtctaacac agcttcacga tagtgagtca
    32101 ttctgtctgt taaatgtcca aaataagggc tttttgtttc agtcatgcgg ggtctccttc
    32161 tttcttacga aattataaac gtttctttcg taactatttt atcatatatt aggacttttg
    32221 cgtatcctta accataagaa gagatagtca ctttattttg cactattgtg caatataggc
    32281 ctgataagtc gttcttcttt ttctaaaaaa ccacctctaa ctggagatgg tctcaagaat
    32341 ttggtggacg ctaaatcatg actcttcact agcttgttca ttttgataag ccatattatc
    32401 ttggatttta aagaatggga agtacaccaa cgttgacatg atgagtataa gaatttgcac
    32461 aatagctcct tgccagccac caaccatgaa ccctgagata atggctggtg ttgaccacgg
    32521 aagggtcact cctgcaaagg gctgcatgaa accaatagca atggcgccat aaactgtgag
    32581 agctgccaag accggaacca agataaatgg caagaacatg actggattca tcacaattgg
    32641 aaaaccaaag acgactggtt cattaacatt aaagagggct gggaaggctg caaccttgcc
    32701 taaagccttg tattgtttgg atttagccgc aaagatcata gctaccacta aaccaaaggt
    32761 aatgccagaa cctgatagaa tcaagaaaga gtctaaaaat tgttgggtta caatatgggc
    32821 acccttgtct agggataact cacctgctgc catcaaggcc ttattggcat ctagatttga
    32881 taagagaaga gcagtgacaa ttccattgac cacagattgc ccatgcacgc caaaccacca
    32941 aagaaaggaa ataaagaagg caatacctag tgcgccataa agagaacccg ttaacccttg
    33001 cagcggtacc tgaatgacat cataaatcat ttcaataaag gtgccaccac ctgttactga
    33061 cttggcaata atatacacaa gcattgacaa ggtaaagatc acaaaggctg gaatcatggc
    33121 ttcaaactgt ttggcgatgg cttgtggcac ttgatctggc attttaatga cgatatgacg
    33181 acggataaat gttgtgtaaa cagctccgac cgttaaacca atcacaatag caccaataat
    33241 cccttgacca ccaaaccaaa ccttactgat agcatctcca atagcttcac cttctgctgg
    33301 aacataagat gatctcaata aaataaagaa ggctgacaag gatagaaccc ctgaagggag
    33361 aggttcaaca cctgagtttt tagcataaga atagccaatt gcaaaacagg aaatcaaccc
    33421 cataatagca aatgttccat ggtaaacctg cataaagggt tctgtccagt cagcaccaaa
    33481 cacactagca atggcatcat taaccccttg gaaaggaatc tgcccagcaa tcaggaaaag
    33541 actccccaca acggtcaaag gtaaaatggc taacataccg tcttttaagg caatgatgcc
    33601 gcgcatattc acaaatgtca tgattggctt gatgatgttt tgcatattca tttttgccat
    33661 gattgactcc tattctttaa caaggctaag ggctaaatca agcaccttgt tgccgtctaa
    33721 cattccataa tcagccattg ggataactgc aatagggata tcattgtctt tacaaatagc
    33781 ttctgattta tccagagtat aggcaacctg tgggcctaaa agtgccacat caagtaatgg
    33841 tgcatagtcc gctaatttcc cttgagcata ggcttcaatc tgacaatcaa tgcctttttt
    33901 ttcagcagct actttcatgt tgttcaccaa cataccggtt gaaaatcctg ctgcacaaaa
    33961 caatccaatt ttaatcatgt caatctcctt tttagtcatg aaaacttatt tagttgccaa
    34021 ttctttacga aggtcaataa tctctttgat gagattaatt tctgtaatgg tcgtcatcaa
    34081 gtgatcctgt gagtgaacaa aaagagctgt aatctctgac ttattaccac tagcttcttg
    34141 ggcaagaaac tgggtctgta aattgtgggc ttctaataag gcatcatctg ctaaggccat
    34201 ttctttttca ctagtggcat aatcgtcctc tttagcacat ttcagagctt ggtagatatg
    34261 ttgtttggca tcgcctgcat ttaaaattaa gcccataatg atttggtctg gtacaataac
    34321 ttgcattggt gtctcctttt tttctttttc atgtgatgta acggcaatga gtcttttttt
    34381 cgaaggtgat gttattgtgt ttgtaatcgt ttacatttcg ttggtaagtt tattgtatca
    34441 tttttgtttt tagggtcaat atattttgtg ctatattttg gttaatgcac ttttgtgcca
    34501 atacattaac tgcacatttg agcaatctct gttttatcaa cacatcaaac aaaaaaagcc
    34561 ctgaccgttt ggtcttgggc ctctataaat atcatagtat ttttgaattt ctattaaaga
    34621 agaacgttat taagatcaat atcttcatct aacgctaaaa cagctagcat ggtctcttta
    34681 tccgtcacta gataattgat aaaacctgct tttaaggctg ccaatattgc cttagccttg
    34741 tgtttacctg ttgcaacagc cattgttttg gggacacgcc tcaactgttc tagtgaaata
    34801 ccaatagttc gatcctgtag gccagtgtaa actggctgac ctgcctgatc aaagaaacgg
    34861 caacaaactt caccaacggc tttttcatat ttgagttggt catgatctga gctggttaat
    34921 aaatcacgcc attggctctg ctcaaggcta ttaggctccc caccaattcc tactaaggca
    34981 agatctaact ggtcccagct tgttaaaatg tcgttaaagt atttagattg taagattccc
    35041 ttagccaagt gtttgtcttc ttgaatgacc atagcgttca taaaagcgct attaccatga
    35101 aagatgcgag ccaagcggta aaccagggta ttgacatggt atttggcatt aatatggcta
    35161 ggtcctcctg ccaaaggata aataaacaca tctttcatcg cttttggatt taactcatcc
    35221 atcaagcaag aaagagtcgc tccccaggac agaccgatct tatcgccatc tttaacaaca
    35281 tgtctaaaaa cctcagctgc tgttttagca acatttgtca aggtatccat tggggtatct
    35341 tcaacctggt tgggcacaag gtctagtttt tccaagccat actgctgtcg cacgtattct
    35401 tctaaagcaa ataaatcagc atcatagtcg gcaatttcaa tccgaacaat gccttcttcc
    35461 ttggcttttg ctaacatccg acaaaccgtt gttcggtaga tattcatttc ctttgaaatc
    35521 aaggtttggc tcttgccttg aacataatgc aagtaagcca ccttggcaag gagccgtctg
    35581 cgttcttctt tcatctagcc acctattttc taagaaacaa aatcaagaac aagaccacta
    35641 gcacttaata actcttgtgt ttgcttgtct agtgcttggt ctgtaatgac gcgattgaca
    35701 tcagctaatg acaactggtg taccagactg gtttttgaaa acttgctgga atcggtcaga
    35761 atcaccactt cctcagcagc atctgccatg taacgcaccc cttctgagcg catcatgtcc
    35821 ttgcccataa agccaagatc tttgttgaaa ccgtctgttc caacaaagac acgattgaca
    35881 tgaaaaaggg atatcatttc tttcaataaa ggaccaacag tcacctctga attgggctgg
    35941 taataaccgc ccagtaaaat gatttgacag ctactatatt gacgaatgta gttggcaatg
    36001 aagcacgaat tggtaatgac tttaatattt cgtttggtct ggcaaagcac ttctgccaaa
    36061 agggcacagg ttgagccaga ttcaatcata atggtatcgt tgtcttgtac caattcagct
    36121 gctttttctg caatccgtcg ctttatgttg taattgtagg acaagcgtac attgaggtca
    36181 tcgccactgt ttagcaccgc atagccatgt tcccgtcgca acaagccctt actttcaagc
    36241 ttatcaaggt cttttcgaat ggttactttc gaaacgtcta attgctctga taaactgtta
    36301 acatctattt ttttcttctg ggaaaccagt tgaataatac gttctaatcg attcatcatt
    36361 cacctccctt tcattgtacc agttattttc ttaaaagaaa agggatattt actttcattc
    36421 gtaattgatt tatttacgtt tatctggtat gatagtttta caacgaaagg aattcacact
    36481 tatgactgat cgcggtattg ttttcaacat ccaacatttt agtattcatg acggtcctgg
    36541 tattcggaca accgtttttt taaaaggttg ccccttgaga tgtccatggt gtgccaatcc
    36601 cgaatcccaa caaaaagcgc ctgagcagat gttaacaagt gatgggctta atactaaaat
    36661 agttggagag gaaaaaaccg tggacgaggt gatcgaagaa gtccttaaag accttgattt
    36721 ctacgaagag tcaggtgggg gcatgaccct gtcagggggg gaaatctttg ctcagtttga
    36781 ctttgcctta gccctgttaa aagcagccaa agcagcaggt cttcacaccg caattgaaac
    36841 caccgccttt gccaaacacg agcaatttgt cacccttgtt gactacgtgg actttatcta
    36901 taccgatttg aaacattata atcagctcag acaccaaaaa gtgactgggg ttcgtaatga
    36961 cttgattatc aagaatattc attatgcctt tcaagctgga aaagaaatcg tcttgcgcat
    37021 ccctgttatt ccccaattta atgattccct agacgatgct aaagccttct cagagctctt
    37081 taatcagctt gagattgacc aagtgcaact gttacctttc catcaatttg gagaaaacaa
    37141 gtacaaactt ctaggtaggg agtatgagat ggctgaggtc aaggcttatc atcccgaaga
    37201 tttagcagac tatcaggctg ttttcctcaa ccataatatt cattgctatt tttaatgtgc
    37261 taagcaagtg aggccaggct gtttatgcgt tgactctgtt acaagctaat ttagtgcact
    37321 tggtttggag atcgttgcta cattgccttt acctttatgc ttttttaaag ctcaaaccag
    37381 tatgggcttt aaaaaagctt accaatcaga ttattgatac tacaaaaaag gctgggaata
    37441 ctcccagcct aggcttttcc aagcaagctt atcatttcta ccaatcttga cctagaataa
    37501 attaatcagt gctaatacac tctttgctaa gagctgatca aagatgtaga taatcaccgt
    37561 aaagaaagct gtgtactcaa gaactgagat aaaatctttc caacgttgtt tacgatttgg
    37621 ccatgttgtg tcttttaaga ctttaaaagt cccgctaatg aatcccatca ggctctcctt
    37681 tttaacgtgt ttctttgtgt aaggtatatg ttttgcagta tttgcaaaat ttatttactt
    37741 ctagacgtgt tggtttaggc gtgctactca ctccgataga gtagttacga ctgccacatt
    37801 cgacacacgc tagactcgct tttttctgtg ccataacgcc tccgtaacta ttattttaac
    37861 acgatctcta aaatactgca agctatctaa aatagtcaac aatctctttc caaatagatt
    37921 gggctttatc acgtaaccct gactgatcga ctgcttttga tagtgattgc gaagcttctt
    37981 gtgctgattt tcttaaacca tcaataatag attgagtatc aactcctgat tgattacctg
    38041 tttcattgac tccataaaca gctgaaatac cattttgagc gtaggcatta tctacatgaa
    38101 attggctgcc cttggtataa ggcaaaatgt aagatgcctg agtgctaaaa atagctgagg
    38161 ccgtgcctgc acttgaatcc gttagataat gattttcatc ggtctgatta aatcctaccc
    38221 attgactaat aacaacatct ggcgtataac caataaccca ctgatcgcct gctaagtcgg
    38281 gattgaagtt ggtttctgtc gtccctgttt taccagctag tgtatagcca tatacgttag
    38341 cattgactgc tgttccattt gaaaaggtac ctagcatcat ggctgtcatc ttatctgcaa
    38401 cagactggct gacaacacgt ttagccttat cagtaaaggt tttaagcact tcacccctgg
    38461 cattttcaat ccggttaatc aagtgcgcag gatggattac tccattattg gcaaaggcag
    38521 catatgcctg agccatctcc aatggattgg ttgtcacgct gccacctaaa gctaccccca
    38581 actctttttt ggcagagctc atatctaacc caaatgtttt accataggta aaggctttat
    38641 cgattccgat atcgttcaat gtagaaactg ctggaatatt ataagagttt gctaatgctt
    38701 gatacatagg aacatcttct gattcataat ttccataatt atgtggctga tagccatcga
    38761 aatcttgaac ggtatttggt agttcttttt caattgacca tcctgaagca acggctggcg
    38821 cgtaaaccac gagtggtttg attgttgatg cgggactacg ttttgcttga gtcgcatagt
    38881 taaaacttct gaaagtcgga ttttcactac tattcacacg accaatcaga cctctaacac
    38941 ctcctgtttt aggatctaaa gcaacactag ctgcttgagc agagctaccg tcataagctg
    39001 aaacaggaaa tagttcatcg ttgttaaaag tcgtctgcat gccagtttgg taattttgat
    39061 ctagctcagt gtaaactttg tatccattat taacaatgtc tttttctgaa agaccataag
    39121 ttgctattgc ttcactaata acagcatcaa agtaggatgg gtatttgtag tcatctgtct
    39181 taccaacata agtatcagct aagcgatttt ttagccctac tgctctagct tgctgagctt
    39241 ttgtttgggt aatctttttg gcatcaacca tcgctcctaa aacagtatct ctacggtgag
    39301 tagcattttt tagagaatgg taagggttat atatttcagg tcctttgagc atacctgcta
    39361 atgtggcagc ttcatccagt gttaagttag cagctgtggt tccaaaatat ttttgactgg
    39421 catcttcaac tccccaaact ccatttccaa agtaggagtt gttaaggtac atagtaagaa
    39481 tatctttttt actgtatttt ttggtcaact ctaacgccaa aaaaaactct cgggcctttc
    39541 gtttaattgt ctgatcttgt gagagataag catttttagc cagttgctgt gtaatcgttg
    39601 agccacctcc aaagcggccc gccgtaacta ccgccaataa gaagcgttta agattaatac
    39661 cgctattact gtaaaaagtc ctatcctcag tggcaataac agcattctca agatcatctg
    39721 aaatagcgtt gagctcaaca taactccctt tttgaccaga taaactgcct gcatactctc
    39781 ctttgtgatc ataaataacc gttgtagcct tcaaggcatc ttgtaaatca gatactttag
    39841 ctgtttttga taagtaaaac aagtatgatc ctaagagtaa gacaagagtt ccaatcagaa
    39901 tcattagcag ttttccgatg tgatagcggc gccaaaaacg ccgaattgga cgttgaggag
    39961 acggcaaaac agcttccagc ttttgcaacc aagcgggccg acttttaggg cttccttcgt
    40021 aggctctact gcgttgcaga gctgttgcag ggtcttgttc tgagtttttg gtagctgatg
    40081 agtccaaatg attggcattt ggcgaatact gcttttgatt gtgttgtggc gttaaacgcg
    40141 ttttttgatg cattaagaat tgtttttcct gatatgcttt aggaaaaaat ttcttttgta
    40201 aaagttctag aaatctcata acgttattat accactatga tcttaaagta accttgatta
    40261 ggtcatcgaa atatgctttg aataagccac accatccact tgaaagagta gtccttgtgg
    40321 tccaccgtga tgtgcaaatt ccgtttgaat cgattttcga gcagggtatc tgccattaaa
    40381 gcgctcttta atcatttttt ccatcacagg tatgttccaa acgtctcgaa atagacaatc
    40441 catttgaaca actgcatcta atgtgagccc caccaatgct aatcggcgct ccatctcgtc
    40501 aaaggctcca ttaatctgac tttcaatgtc ttgtccaaca ttgccgacac aatagtttaa
    40561 ataatagaaa tctcctgctt ctacaaggcc tgtatgccct ctatcttcgt taacatcata
    40621 acgtctaatt gttttcattg tttttcctct attttacgat tatgttttta tcacaattat
    40681 aacaattttt cttaatattt tatattaaaa acctttggtt gacttctttt acgatagaga
    40741 aatacctatc ataaggccaa actaatccgt atttttccga tacgtcgttc aacctcatgg
    40801 ggttgttttg aaagaacata cctgtttgac tcatcgtctt aggtaactat gtgttgataa
    40861 gttttatctt gctatttttt atgactgttc caacttcgca acacgttagt tgttttctat
    40921 ttctgcgtta gcacctagtt tcatatcatt tctgttacaa actctatcaa gaggtcttat
    40981 ttaagacact ttcttattag atggattagc aaaataacgt ttttaccttt ttgagtggca
    41041 cgttttgatt agaaacatgc tataatagca ttgaattcct tgcattaatc aggagctcac
    41101 attaaacata gaaggacggg tttaaccaat gaataaattc caagctttta aagaaacctt
    41161 atccgcagaa agtctaaaag ccatttacga tgagactcgc ttggaggtag ctaatgacga
    41221 gcgtgaaggt actgaagctt tctctgctgc tcttgccacc caaatggcta tcaaccttgt
    41281 tgaaaaatac cataactggc tcaatgaaga caacaaataa accatcaaag gggtttactg
    41341 tcacactgaa aaatcccttt gaagaattga cggtcaaagc attattagag gaacaattgt
    41401 taattccccg taaaattagg cattttctga gaactaaaaa acatgttctt attaatggtc
    41461 attctgttaa ctggcaaagt tgtgttaaat acggtgatca ggtcaaactt ttttttgatc
    41521 acgaagatta tcctgaaaag attatcgtga tggggcaggc cgaaaaagta acctgccttt
    41581 atgaagatga gcacatcatt attgttaaca aacctgaagg gatgaaaaca cacggcaatg
    41641 atccaacaga gttggcgctg ctcaaccacg tgtctgctta cacgggacag acctgctatg
    41701 tggttcatcg tctggataag gaaacaagtg gggccatttt atttgctaaa acacctttta
    41761 tcttaccaat ccttaatcgt cttttagaaa aacgagatat ccatcgagaa tatttggcac
    41821 tagttcacgg atccttagac agtcctaggg taacttacca tcatccaatt ggtcgtcatc
    41881 gacatgaccg cagaaaacgt gttgtcgatc cgataaatgg caagaaagct attactgagg
    41941 taactctagt caaaaacttc cacaaaacgg caagcttact cacttgtcaa ttacaaactg
    42001 gacggactca tcaaattcga gtccatttag cccatcaagg tcatgtttta tttggtgatc
    42061 ctttgtattc caatggaaaa aaagattgtg ctcgactgat gctccatgct tatcaattac
    42121 gtttgaaaca ccctctaacc caagaagaca tttgcgtgca agctaaatca gctacatttg
    42181 acgcagtctt aaacgctcaa aaggctagga aataatctcc tagccttttg agtttatctg
    42241 ttttcatagc actgtatttg agcgataaca ttgtttctac tgttctttgt ggctttgcat
    42301 cctttatggt tgcttttgca aagttactcc cgaaagtggc ttggtataat caaattcatg
    42361 tgttaatgct gcctgccaca ccactggaga ggctgtttta ccagatattt tgaaaccata
    42421 agcatatttg acatttgcac cccccaatcc tccttctgga actaaggcgc ttatgtcact
    42481 tccaggatct ggcgtataaa gataaaaacc attgcctttg tcttcaactt tactaatttt
    42541 agctgtccga gtttctttag aacggttgcc tttttgatct tcaactttag tcgtaattgt
    42601 tccatctgat gctagagaca tatggatgct caaaccattg gcttggcctg tccacgttcc
    42661 caaaatagac tcaggaaaga cagatggcgc tttgagttga ttgtcctctt taacaacagt
    42721 aatatttttg gagccggact ggctgataag gtaatgctgt ccaacttttt ttacagtcac
    42781 ttttccagtc aagtcttgat taatatgtcc agaggtatgc tgctcaggat ctgttgactt
    42841 gtcatacaaa aattcgtagg tagctgtgaa atcaagcacg taagttgttt tacccacttg
    42901 agtcattgtt gtcaaaagga tagatggaat attgagacgg ctggcttttc ttgtatctgt
    42961 ctgaaatttc gcttttatgg actctttcaa tcccctataa aatgcgttgc tagaccctgc
    43021 ctcaaagacg ctacgtaagt tagatgagtc ttgacctgta ctgaggtagt gcatcagctg
    43081 atcaaaagct gatactaata gctcccctgc cttgtcctct tctaaaagat ctgtaactaa
    43141 aatctccagg gttgctcctt cttcaacatc agctagagca tatttttgtg atcttaactc
    43201 accatctggg aatgttgttt tcatataagc ttgtgcgttt tctgtaacag ggtaatcttc
    43261 tacttgtaat tgaccatctt ttaatgtgcc aatatggtta tcatcgaagt aaagatctcc
    43321 ttgcttagca ttgcttgtta ccaaaaaagt tctaaaagac acactcaaat ctagcacggg
    43381 attatcacca tcatatgatt tgttgacttt aatgtttcgc ccgttgtgtt tgcctctgat
    43441 acttgcggta tattctgccg ttggtagccg atcaagcttg actgagaact gttctgaatc
    43501 agaaacagca actttttttt gatttaaaag aacgtctgct tgaggcacat tcgtttttat
    43561 cgttaaatcc atgggtttta tggcaatccg ataatcagga aaaatccaaa aacgacgacc
    43621 aacagacttt acttgaacgg cactatcttg actagcggct tttaaatcct gctttttttg
    43681 cctcaattct ttctgactat accttctaaa cttagtatac atcgcctcgt catttgtgat
    43741 ctgctcatta gtatcatccc agactagata tgctttgata ttctcaaaaa ctggtcctga
    43801 ttgggccgat cgagctttaa gataggcatt aatacaatga tttttagagt agtaaaaggc
    43861 accaccgatc aggaataaaa aaaggctagt tgcagctatt atagttattt gttttagttt
    43921 cttatgatga aatggtttgg tcatcaacag accccaactt tctatgtttt tctttactat
    43981 tatatcataa atggctaatg gattttcgaa gaaacctaga tagttcactg cctatacatt
    44041 tttaggggcc gttaagccaa aattcaagag agaattctca taatatttag atagctaaca
    44101 atttcaaaac acttcataaa agacttgaat ttttaaaaag agcattttat aatgtctgtg
    44161 aaagcgttat cgtttactag gaggattcgc atgataaaca aaaaaatatc acttggagtt
    44221 ttaagtattc tgacagcctt ttcgcttcaa agtgttagtt atgcttgtac tggttttatt
    44281 attggcaaag atttaaccaa agacggttct cttctttatg gtcgaacaga agatcttgag
    44341 ccacaccata ataaaaattt cattgtacgt ctagcaaagg acaatcctgc tggcgaaaaa
    44401 tggaaagacc tctctaatgg ttttgagtac ccgttgcctg agcattctta tcgctatagt
    44461 gcgattcctg atgtaacacc taacaaaggc gtttatgacg aagctggttt taatgagttt
    44521 ggcgtctcta tgtctgcaac agtatcagct tcagctaatg atgccatcca aaaaattgat
    44581 ccttacgtca aaaatggctt agcggaatca tctatgacca gtgtcatttt accaagtgtc
    44641 aaaacagccc gtgaaggtgt cgcattgatc gctaaaatag tcactgaaaa aggagctgct
    44701 gaaggaaata ttgttacctt ggctgacaaa gacggcatct ggtacatgga aattctctct
    44761 ggtcaccaat acgttgccat caaattccca gatgataaat acgctgtttt tccaaatacc
    44821 ttctatctcg gacatgtcga tttcaatgat aaggaaaata cgattgcctc agaagatgtg
    44881 gaaaaagtcg ctaaaaaagc caaatcttat accgaagttg atggtaaatt tcatattgcc
    44941 aaatcttaca atccaccact aaacgatgcc aaccgctctc gctctttctc agggattaaa
    45001 tcacttgacc ctgattcaaa agtaacttat aaagacagca attatgagtt gctccaaagc
    45061 actgataaga ccttcagtct agaagatgcg atgaaactgc aacgtaatcg ttttgagggg
    45121 ctggatctta aaccacttga tcagatggca ttagacggta agggtaaacc aaaatccaaa
    45181 aaagctgtta aaggttatgc ttatcccata tcaaatccta atgtcatgga agctcatatt
    45241 ttccaactga aaaaagacat ccctgctgaa ttgggtggtg tcatgtggct atctattggc
    45301 agtcctcgta atgcccctta cttgccatac cttggcaata tcagtagaac ctatgaagcc
    45361 tatcaagaaa aaagcaccca atataacgat aagtcatggt attggacggt gtcacacatt
    45421 aatgatctcg tggctgctca tccaaaacca tttggaacta aagtgattga tgagatgaaa
    45481 ggcttggaaa aaacctggat agccgaacaa gacaaaagca ccaaagaaat cagtgactta
    45541 gtcgtcagtg accccaaagc tgctcaagaa aaagctgata agatttcact agatcgcgct
    45601 gaaaaaacct tcaaacgctt aaaagctatt gaagccaagt tggttaaaga aaaacccaaa
    45661 aacaagaaag gcttgaatag atcataatac cataacccaa aaaagcttgt atcaacaagt
    45721 ttctccataa ctagagctga agtcaaaaaa taaggtctca cactttgtga aaccttatcg
    45781 gtataggagg ggtgaataag atgggaatcg ggttgagata gcattagttt aagacgatac
    45841 ttctacaacc aaatacttat cctattaagg aatgacatta gtatactaga taagacttaa
    45901 agaaacctta agccaaaaaa acaacaagaa acctctttca cccctttttt cttatactat
    45961 actaaaaggt ggtgaatctg gtgatagcaa cggttagaga ctggggcaat atgtgtgtca
    46021 aacataacga tatgatttta tgactccata gacaacacga taacttccca ggatgggtcc
    46081 agccagaagg taaagtcgag ccctgcgaat ctttctttga agcggcttta tgagaactaa
    46141 aagaagagat agatctgaca gctttaaacc ttcaattaaa gggtatttct agctttatcc
    46201 agcctgacaa aaaaagaggg ctatgtctat tatgactttc tatgtgaatc ctttgaagga
    46261 gagctactga cagagtcgcg tgagggactc ccaaaatagc atgccatagc agacttagac
    46321 atgctggata tgccaaaaga tatccgtgaa catctccttc ttatcagttg atgctagttg
    46381 agcatgaagt aactgcttca agccatcact atcttgaatt gtgttgtcac gatgaaaatc
    46441 atggacagca tacataaact catcaatggg catgttactt tcatccaaaa tcagcataaa
    46501 tgtcgatatg gttaagtccg tctccccttt ttcgaaacgc gacagctgag aggttgatat
    46561 accagccttt gcgacatctt ttaatcgtaa tccctttgat tctctaaagg ttttttaaaa
    46621 tctctccaaa atgattcatc acagacctcc aacacccata tatgggaata acttttcatt
    46681 gactccatga tagcacatga caaagaaaaa caatgtattt tccaatacat taaaagtctg
    46741 taaccacaaa gattggcatt ttatatcaca actaaaaaaa caaagatggg atatcatgag
    46801 tcgaaatcca atctttgttc ttttttcata gtaagaagca gacctttagt ctcaacttct
    46861 ttttcataat ccttaatgct atagagagct tagaagccgc ccatcattcc tggatccata
    46921 cctgctggca ttgctggcgc tggcgtagct ggttcaggtt tattagcaac aactgcttct
    46981 gttgtcaaaa taagactagc tacagaagct gcattttgaa gcgctgatcg tgttactttg
    47041 acagggtcaa tgattcctgt tttaatcata tcaacccact cacctgttgc agcattaaat
    47101 cctgttcctg cagggctgtt tttcaacttg tcaataacta cggagccttc gtacccagca
    47161 tttaaagcaa tttgacgtac aggctcttct agagcacgaa gcacaatgtt acgtccagta
    47221 gcatcatcgc cctcaagctc aagagctgct actttttcaa taaccgtaat aagtgctgtt
    47281 ccaccaccag caacgatacc ttcttcaacg gctgcacgtg tagcatttag agcatcctca
    47341 atgcgaagtt tcatttcttt taaagctgtc tctgttggag ctcctacttt gataacagct
    47401 acaccaccag ctaatttcgc caaacgttct tgtagttttt cacggtcaaa gtcagaagtt
    47461 gttgtttcta attgcgattt aatcagtgca atacggttag caatagcttc tgaacttcct
    47521 gaaccttcaa caattactgt gctatcttta tcaactgtaa tcttagcagc ctgtccaagg
    47581 gctgtcattg tagcatcttt taattcaagt cctagatcct ctgtaatcac tgtaccacct
    47641 gtcaagatag caatgtcttc aagcatagct ttacgacgat caccaaatcc tggcgctttg
    47701 acagcaacca cattgaaagt accacgaatc ttgttcaaga caagggttgg aagtgcttca
    47761 ccatccacat catctgcaat aatgagtaat ggacggttgg ttttaagaac ttcctcaagt
    47821 agtggcaaaa tgtcttggat gtttgacact tttttatccg tgattaagat aaatgggttt
    47881 tcaaggtctg caaccatttt ttcattgtct gtgaccatgt attgagacag gtaaccacgg
    47941 tcaaattgca tgccttcaac cacttcaagt tctgtttcca tacctcgaga ttcttcgatg
    48001 gtaatcacac catcgttgcc cacacgctcc atagcttctg agatatactc tccaactttt
    48061 tcagagcgtg atgatactgc agcgacctga gcaatagctt ccttgccaga tacaggttga
    48121 gcaatggctt tcaaggcttc aacagctgtt gctgttgctg tttcaatgcc tcgacggata
    48181 ccaattggat tagcacctgc tgtcacattt tttagtcctt catgaacaat ggcttgtgtc
    48241 aaaactgttg cagtagtcgt cccatcacca gcaatatcat tggttttaga agccacttca
    48301 gacaccaatt ttgctcccat gttttcaaaa tgatcttcta attcgatctc tttagcaatg
    48361 gttaccccgt cattagtaat taagggagaa ccaaaagctt tttcaagaac aacattgcgc
    48421 cctttaggac caagcgttac tttgacggta tctgctaaca tatcaactcc gcgcaccatg
    48481 gcagcacgcg catctgctga aaatttaata tcttttgcca tattcaatcc ttctttctat
    48541 ttagagattt gtcgttttat tttgtaacaa tagcaatgat gtcagattca cggatgatag
    48601 aaactttctc atcatctacg gttacttcta aatcatgccc attttcaact aaaacctctt
    48661 gacccactga aactgaaggt agcacgctat cacctgtaat agtgcgaaca cccgtttcac
    48721 tgacagcgag gactgtcgct tttcgtgttg actctttatg agtgcctgca aggacaaaac
    48781 caccgactgt ctgctctttt tcatcatcaa atcttacgac cacacggtca cctaatggtt
    48841 ttaacatgaa attttcctcc aataaaagaa tctttagtaa agttagcact catgttcatc
    48901 gagtgctaac tttatattct attttatcac ttggtcaaaa atagtcaaga aaaaagaagt
    48961 tatttttgta agaataacct ctttttttgg tgacatcaag gatgatccac cttttatatg
    49021 gaaattaagc tatgtgaaac gttaatttgc catgtgataa tccaattttt agcgtatgcc
    49081 cacttgtcaa ttctcgagaa agaataagct ctgatagctt atcttctatc tcagtttgca
    49141 gcgttcgacg taatggtctt gcccccatat gctcatcata gccgacctcg gacaaatgtt
    49201 tcaaggccaa aggctgaatt ttaagggtaa tacctttttc tgccaatgta gtaatcaggg
    49261 gctgtaccat gattttaacc acatcgcgca tgttatcttg ggtcagacta tgaaagacca
    49321 ctttttcatc aatacgattg ataaattctg ggcggtaagt ttttcttaat tcttctaaaa
    49381 tacgtttctc catagcttga tggtcttggt gaatgtcttt gaccccaaaa ccgaccgttt
    49441 tatcatcgcg cagggctgtt gcgccaagat tgctggtcat gataataata gtatttgaaa
    49501 aatcgacctt acgcccacga ctatcagtca atataccatc atctaatact tgaaggagaa
    49561 cgttaaaaat atcaggatgt gctttttcca cttcatcaaa aagcaagact gaataaggtt
    49621 tatttctaac tttctgtgtc agttcacctc cttcatcata gccgacataa ccaggaggtg
    49681 ctccattaag cctagacgct gcgaattttt ccatgtactc agacatatca aaacgaataa
    49741 gcgctgcttc atcatcaaag agaacttctg caagggcctt tgctagttct gtcttaccta
    49801 ctcctgttgg gccaagaaac ataaatgatc caataggacg ttttcctgtt cgaatacctg
    49861 actgattacg acgaatggct cttgaaatag ccgtaacagc agcatcctga ccaatcacac
    49921 gcttatgcag ttctttttct aaattgaggt attttttact atcagcttgc gtcagttttt
    49981 caagtggaat tcccgataac ttactcaagg ttgccaaaat atcatcttct gtcaccggtg
    50041 ttggttttct catctgacct tttgcttctt tagctaagag gcgagatact tttttcatat
    50101 caccattgat aagagcttgg tctattggtg ttaaagtctc aggtgctgat tttttcacca
    50161 tgttttgcac agcagcacta gcttcatcta gtaaatcgat agctgaatca gggagatttt
    50221 tactggttaa ataacggtgt gccattttta cagctgtttt aactgcctca tttgatatcg
    50281 agacattatg gtaggtctca taagataatt ttaggcccat caaaatctga taagcatctt
    50341 ctgtattagg ttcttcaatt aatattttag caaaacgacg cgaaagagct gcatcttttt
    50401 caatatgttt ttggtattct tcttgagttg ttgctccaac catatgaaga gtgccgcgcg
    50461 ataatgctgg ttttaaaatg ttagccgcat caagtgtact gtcaatacca ctgccagaac
    50521 ccataatagt atgtagttca tcaacaaaaa gaataatctg accatcagct tcaatatcat
    50581 caatgatttg attcatgcgc tcttcaaaat ccccacgaaa acgggttcct gctaccacac
    50641 tcatcatgtc taattctagg acacgcatct ccttaagttc ataaggaata gcgccatttg
    50701 caatccgttg agcaaggcca taagcaagcg cagttttacc aacacctgca tcacctacca
    50761 agacaggatt gtttttcgtt ttacgactta gtacctgaat catacgagat acttcttggt
    50821 cacgtccaat caccgattct aacaaacctt gtcttgccat ttcagtcaaa tctcttgtga
    50881 aatcactcaa ctcaccagct gtacttggtg gcttcatcat atctgaaaag gtcccttgtg
    50941 ttttcgtttt tttaggctta cgtagttcgt gaatagcctt gatcatttcc ttactgtaac
    51001 ctgcatgacg ttctattgct tttcgcaagt cagctaatcg cggctgccca ttgccgttat
    51061 cttttatctg atagccagct atttctaaca aacgactcgc cataatatct ggattcaata
    51121 aaatagcaaa taagacatgc tcagagccga cttcttgatc cctagtgatt tggctaatag
    51181 cctgcgcaaa agctaacaag ttagtcaaag ttttagattg aggtctgaag tctacacgag
    51241 acaactgttc tttaggggtt ttgcccatgg ctaaaatagc tgcagcttca tattcttcta
    51301 tggcgacttg ggcatcatat tcacttaaaa tcatatttgc taaagaatta tctacagcta
    51361 ccatagctaa caaaacatgc caagtttcca ggcaatggct atcaaagcga gcagcttgga
    51421 actgcgcctg tctaaaaatg tcttgcatct tcgttgaata cataatcatt aattgcttcc
    51481 ctttctgtca attcgttgca ataagcgata gagcattcgt gcacgaatag ttgaaccatc
    51541 agttcctaaa acatcatcag acgccacagc caaaatgata tttccctcac gctctgtcaa
    51601 taagtgttcg tcaaaaagca attgtatcga gtccgtgaaa acttgctcac tgatacagtc
    51661 ttcaatagtt gccattaaat tgccaatcag atggtgtttg tctgaaaaat gaaccttggc
    51721 aatacgaata tagcctccac cacctcgttt actctctact tcatagcctc gactctccgt
    51781 aaaacgggtt ttaatgacat agttgatctg acttgggaca acttgaaacg aatctgctag
    51841 catggaccgc ttaatttctg ctattcctga cttagctaat aattctttaa tatactcttc
    51901 aatgctgtct gaagtatttt tggttggcat gctgtcactc ctttgcttgc gggctactct
    51961 aaaaacttag tagcaccacg tcaatacatt ttgactaaaa ctgactatta ttataacaaa
    52021 tacaagacct taaacgcaac tcttaatcat taaaggtaac tggtagaaat caaaaaagca
    52081 gttgctgttt ccaacatctg cttctcttta gttactttaa ccagattagg ccaatttagt
    52141 gatattgact gcttgaggtc cacgttgacc ttcttcgacg tcaaatgcca ctttttgtcc
    52201 ttcttctaac gttttaaaac cattagtttg gatggctgaa aaatgtgcaa agacatcttg
    52261 accgttttca gttgaaataa aaccaaaacc tttttcagca ttaaaccatt ttactgtacc
    52321 ttgtgccata tacatccact tcctttctaa aaatcatttg taaaaataga gagaaataaa
    52381 gatgttgaaa cacaaatact aactcaaaaa ctaatttact cactaagagt aacacatttt
    52441 ataacacttg tcaataacat gcttaaaaac attaagaata tagttgcatt gtaatgggtg
    52501 gttactttat aaagctgact tggtaaggta aacaagtaga gattcaactc tactcgctct
    52561 cacatcaccg tgtctatcgt taaggtgcac ggcagttcaa ctaactttta acgcatatcg
    52621 tttaaggggg taagaactct gacctttatt tgcaatcgtt taccaatttt ggccatagta
    52681 tttttcatac ctaataatca ggctctaaaa gacatcttcg ggaaatttga ccgacttttg
    52741 accgacttta tttctttttt tctctttttt tatcctgccg caaaaaataa aaaccttgat
    52801 ttaacaacgt tttcacgaag ttaatcaagg cttgttttgt atataaaagg cggtagacgg
    52861 atttgaaccg acgatcaagc ttttgcagag ccgtgcctta ccacttggct ataccgccac
    52921 aacaaagatt attttaccct aattccacaa atccgtcaag cactatttgc acaagacata
    52981 tccaattaat ataacagcca ttccctgatc tcatgccaaa ataggttaca atattagcga
    53041 ttaggtaacc ataatattaa gttgccttaa cggaatcaaa aaagtttttt gtaaacgctt
    53101 taataacaat tatatttt
//
LOCUS       DAUGQX010000009        50874 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUGQX010000009 DAUGQX010000000
VERSION     DAUGQX010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50874
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.009"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            202..939
                     /locus_tag="VIA51_000439"
     CDS             202..939
                     /locus_tag="VIA51_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEQ8682405.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYETPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            978..1478
                     /locus_tag="VIA51_000440"
     CDS             978..1478
                     /locus_tag="VIA51_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8682406.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            1493..2182
                     /locus_tag="VIA51_000441"
     CDS             1493..2182
                     /locus_tag="VIA51_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEQ8682407.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASSAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            2360..2602
                     /locus_tag="VIA51_000442"
     CDS             2360..2602
                     /locus_tag="VIA51_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEQ8682408.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            2780..3574
                     /gene="racE"
                     /locus_tag="VIA51_000443"
     CDS             2780..3574
                     /gene="racE"
                     /locus_tag="VIA51_000443"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEQ8682409.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            3571..4557
                     /locus_tag="VIA51_000444"
     CDS             3571..4557
                     /locus_tag="VIA51_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEQ8682410.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRHQSPLSLITFIIDMINQETQREIKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEADWPGYIATQPKG
                     ENGFGYDPVFIVGETGHHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            4536..5057
                     /locus_tag="VIA51_000445"
     CDS             4536..5057
                     /locus_tag="VIA51_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEQ8682411.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVV
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            5054..5515
                     /locus_tag="VIA51_000446"
     CDS             5054..5515
                     /locus_tag="VIA51_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8682412.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            5512..6258
                     /gene="xerD"
                     /locus_tag="VIA51_000447"
     CDS             5512..6258
                     /gene="xerD"
                     /locus_tag="VIA51_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEQ8682413.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLIGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPMTLEKYYKS"
     gene            6258..6959
                     /locus_tag="VIA51_000448"
     CDS             6258..6959
                     /locus_tag="VIA51_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEQ8682414.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEDLEQDLLEKIEEYSRFKAVSQ
                     ALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKNNHTVI
                     ERDDYKIEDMMASIKQRLEKENVIRLSAIFEECQTLNEVISIFLASLELIKLHVVFVE
                     QLSNFGAIILRKEKK"
     gene            6956..7507
                     /locus_tag="VIA51_000449"
     CDS             6956..7507
                     /locus_tag="VIA51_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEQ8682415.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            7630..8352
                     /locus_tag="VIA51_000450"
     CDS             7630..8352
                     /locus_tag="VIA51_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8682416.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKSRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            8349..8612
                     /gene="yidD"
                     /locus_tag="VIA51_000451"
     CDS             8349..8612
                     /gene="yidD"
                     /locus_tag="VIA51_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEQ8682417.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            8790..9338
                     /locus_tag="VIA51_000452"
     CDS             8790..9338
                     /locus_tag="VIA51_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEQ8682418.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      9447..9570
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            9649..10212
                     /locus_tag="VIA51_000453"
     CDS             9649..10212
                     /locus_tag="VIA51_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8682419.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            10214..10867
                     /locus_tag="VIA51_000454"
     CDS             10214..10867
                     /locus_tag="VIA51_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8682420.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILLIGLSRIYLGVHYPSDILAGFVLGFGILHFIYPFYKQKRFEWRFLLKQD"
     gene            11160..12080
                     /locus_tag="VIA51_000455"
     CDS             11160..12080
                     /locus_tag="VIA51_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEQ8682421.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            12119..12673
                     /locus_tag="VIA51_000456"
     CDS             12119..12673
                     /locus_tag="VIA51_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8682422.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADF"
     gene            12806..14140
                     /locus_tag="VIA51_000457"
     CDS             12806..14140
                     /locus_tag="VIA51_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEQ8682423.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            14218..15009
                     /gene="pflA"
                     /locus_tag="VIA51_000458"
     CDS             14218..15009
                     /gene="pflA"
                     /locus_tag="VIA51_000458"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEQ8682424.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            15140..16075
                     /locus_tag="VIA51_000459"
     CDS             15140..16075
                     /locus_tag="VIA51_000459"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEQ8682425.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            16151..16804
                     /locus_tag="VIA51_000460"
     CDS             16151..16804
                     /locus_tag="VIA51_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEQ8682426.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNRVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDFVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(16849..17886)
                     /locus_tag="VIA51_000461"
     CDS             complement(16849..17886)
                     /locus_tag="VIA51_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8682427.1"
                     /translation="MLFMVNKKRRPLLKSQRHLLRLYTSLILLLVSLMGLALSLGESH
                     LSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(17847..18899)
                     /locus_tag="VIA51_000462"
     CDS             complement(17847..18899)
                     /locus_tag="VIA51_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8682428.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(18889..19821)
                     /locus_tag="VIA51_000463"
     CDS             complement(18889..19821)
                     /locus_tag="VIA51_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8682429.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAVTTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEDKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEIIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(19847..20629)
                     /locus_tag="VIA51_000464"
     CDS             complement(19847..20629)
                     /locus_tag="VIA51_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682430.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(20875..22320)
                     /locus_tag="VIA51_000465"
     CDS             complement(20875..22320)
                     /locus_tag="VIA51_000465"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEQ8682431.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            22408..24042
                     /locus_tag="VIA51_000466"
     CDS             22408..24042
                     /locus_tag="VIA51_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEQ8682432.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEERAIHLFVAVLFQTLLLALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            24210..24839
                     /gene="upp"
                     /locus_tag="VIA51_000467"
     CDS             24210..24839
                     /gene="upp"
                     /locus_tag="VIA51_000467"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEQ8682433.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            25063..25653
                     /locus_tag="VIA51_000468"
     CDS             25063..25653
                     /locus_tag="VIA51_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEQ8682434.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            26145..26420
                     /locus_tag="VIA51_000469"
     CDS             26145..26420
                     /locus_tag="VIA51_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEQ8682435.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            26669..27304
                     /locus_tag="VIA51_000470"
     CDS             26669..27304
                     /locus_tag="VIA51_000470"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEQ8682436.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQDILTTREPGG
                     VAISEHIRELILDINHTAMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            27322..28197
                     /locus_tag="VIA51_000471"
     CDS             27322..28197
                     /locus_tag="VIA51_000471"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEQ8682437.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHVYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHINAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            28216..28455
                     /locus_tag="VIA51_000472"
     CDS             28216..28455
                     /locus_tag="VIA51_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
                     /protein_id="HEQ8682438.1"
                     /translation="MGKRSLSKDLPVATKVAAHKGKKAFEENTAFATDLMKEVSRLIT
                     QNQLEMTFVNSVFLLDQHVVLIPFSAEEHMDFYNC"
     gene            28860..29183
                     /gene="yabA"
                     /locus_tag="VIA51_000473"
     CDS             28860..29183
                     /gene="yabA"
                     /locus_tag="VIA51_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEQ8682439.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            29188..30051
                     /gene="rsmI"
                     /locus_tag="VIA51_000474"
     CDS             29188..30051
                     /gene="rsmI"
                     /locus_tag="VIA51_000474"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEQ8682440.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQADSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            30078..30470
                     /locus_tag="VIA51_000475"
     CDS             30078..30470
                     /locus_tag="VIA51_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682441.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(30517..31146)
                     /locus_tag="VIA51_000476"
     CDS             complement(30517..31146)
                     /locus_tag="VIA51_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEQ8682442.1"
                     /translation="MIKEFCAENLTLLPTLDAGQISRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDRIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGITAENCQSLSQLTGTAIVHGTKII"
     gene            31445..31801
                     /locus_tag="VIA51_000477"
     CDS             31445..31801
                     /locus_tag="VIA51_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEQ8682443.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGN
                     VLQVGYRKPYQELDLG"
     gene            complement(31875..32702)
                     /gene="xth"
                     /locus_tag="VIA51_000478"
     CDS             complement(31875..32702)
                     /gene="xth"
                     /locus_tag="VIA51_000478"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEQ8682444.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPNSNRRSPGFTDEERQGFTNLLARGFTDTFRHVHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            32936..34117
                     /gene="lctO"
                     /locus_tag="VIA51_000479"
     CDS             32936..34117
                     /gene="lctO"
                     /locus_tag="VIA51_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEQ8682445.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDYLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            34380..39323
                     /gene="scpC"
                     /locus_tag="VIA51_000480"
     CDS             34380..39323
                     /gene="scpC"
                     /locus_tag="VIA51_000480"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEQ8682446.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPT
                     ITNHAQQQAQHLTNTELSSAESKSQDTSQITLKTNREKEQSQDLVSEPTTTELADTDA
                     ASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFD
                     EDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKY
                     ESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDIMGSAESLFIKAIED
                     AVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDP
                     LATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVD
                     FKDIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKHG
                     ALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVS
                     KAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIA
                     GASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNI
                     DGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKDKTLRYDTELLTDHVDPQ
                     KGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRF
                     RDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGK
                     HFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNN
                     QDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTL
                     LGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDP
                     ETNRFKPEPLKDRGLAGVRKDSAFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQA
                     DGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKE
                     TLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKG
                     LKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGDYQ
                     YVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVRE
                     EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVED
                     RAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYY
                     NNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQ
                     ITAHFDHLLPEGSRVSLKTAQDQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRI
                     EGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKSTTSAT
                     AKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            40094..40801
                     /locus_tag="VIA51_000481"
     CDS             40094..40801
                     /locus_tag="VIA51_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEQ8682447.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVIL
                     TGIAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            41044..43041
                     /gene="metG"
                     /locus_tag="VIA51_000482"
     CDS             41044..43041
                     /gene="metG"
                     /locus_tag="VIA51_000482"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEQ8682448.1"
                     /translation="MKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEVF
                     YLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHEE
                     VVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGHE
                     VEWVSEESYFLRLSKYDDRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRTT
                     FTWGVPVPSDPKHVVYVWIDALLNYATALGYRQANHANFDKFWNGTVFHMVGKDILRF
                     HSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRYY
                     LMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGTA
                     FDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGDK
                     AQLASVMAHLAASLRLVAHVIQPFMMETSAAIMAQLGLEPVSDLSTLALADFPANTKV
                     VAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDAV
                     EIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKFYPNEQELVGKKLQIVAN
                     LKPRKMMKKYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            43536..44549
                     /gene="nrdF"
                     /locus_tag="VIA51_000483"
     CDS             43536..44549
                     /gene="nrdF"
                     /locus_tag="VIA51_000483"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8682449.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            44553..45041
                     /gene="nrdI"
                     /locus_tag="VIA51_000484"
     CDS             44553..45041
                     /gene="nrdI"
                     /locus_tag="VIA51_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8682450.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVSKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            45008..47188
                     /gene="nrdE"
                     /locus_tag="VIA51_000485"
     CDS             45008..47188
                     /gene="nrdE"
                     /locus_tag="VIA51_000485"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8682451.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYSDGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(47391..48143)
                     /locus_tag="VIA51_000486"
     CDS             complement(47391..48143)
                     /locus_tag="VIA51_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEQ8682452.1"
                     /translation="MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLIYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            48584..49138
                     /locus_tag="VIA51_000487"
     CDS             48584..49138
                     /locus_tag="VIA51_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682453.1"
                     /translation="MKWSGFMKTKSKRFLNLATLCLALLGTTLLMAHPVQAEVISKRD
                     YMTRFGLGDLEDDSANYPSNLEARYKGYLEGYEKGLKGDDIPERPKIQVPEDVQPSDH
                     GDYRDGYEEGFGEGQHKRDPLETEAEDDSQGGRQEGRQGHQEGADSSDLNVEESDGLS
                     VIDEVVGVIYQAFSTIWTYLSGLF"
     gene            49412..49663
                     /locus_tag="VIA51_000488"
     CDS             49412..49663
                     /locus_tag="VIA51_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682454.1"
                     /translation="MPEKKVLPVLSIVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLVLAALAVAVVAYAYYDPTVIPY"
     gene            complement(49757..50389)
                     /locus_tag="VIA51_000489"
     CDS             complement(49757..50389)
                     /locus_tag="VIA51_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682455.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDEQSSTQKPVKFDLDGPQQKI
                     KDYSGNTITLEDLYVGSKVVKIYIPQGWWVYLYRQCDHNSKERGILASPILEKNITKT
                     DPYRQYYTGVPYILNLGEDPLKKGEKLTFSFKGEDGFYVGSYIYRDSDTIKKEKEAEE
                     ALQKKEEEKQQKQLEESMLKQIREEDHKPWHQRLSESIQDQWWNFKGLFQ"
BASE COUNT        15887 a         9707 c        10472 g        14808 t
ORIGIN      
        1 ttgtctactt cctgtcactt ttactaaaga caagaataca aaaatgagat agttagtagt
       61 actaacagta aaagaggttt gtctatttta aaaatagtat caaaaaaagg tcttttaggt
      121 ttaaaacatt gaactgaccc caaattgacc atctaagaag ttgatgcttt caaatgctgt
      181 cgcgtatggt ataataggcg catggttatt acatcaaaag caaatcaact aattaagcaa
      241 acaaaaaaat tattgcaaaa aaagcatcga aaacagtcct atttgattga gggctggcac
      301 ctttttgaag aagcccaaaa atcaggacaa gtttttcgcc acatctttgt tttagaggaa
      361 atggtggagc gtctagcagg tgagcaagaa ctcgttattg ttagcccaca agtgctcaag
      421 gagttgactg actctcctag tccacaaggc attgttgctg aggtggagat acctaagtta
      481 gcctttccat cagattacaa agggaaatat ttggttttag aggacgtcca agacccagga
      541 aatcttggga ccatcattcg tacagcagac gctgcacggt ttgatggggt ctttctttct
      601 gaaaaatcag cagatattta caaccaaaaa accctacgtt ccatgcaagg tagccatttt
      661 catttaccaa tttggcgaac agatgtctat cagctttgtc gagagctcca agagtatgaa
      721 actcccatcc tagcaacaac tctgtcaaag aaatctgttg attataaaag cctcacacat
      781 catgaaaggt tagctttggt gttgggaaat gaaggccagg gcattagtgc tgaaatggca
      841 gccctagcag accaactggt tcatattaca atgcctggtc aggcggaaag tttgaatgtt
      901 gccgtagcag caggaatcct cattttcagc ttgatttaag ctaatatgat ataataacca
      961 agtgaggtaa ttatgttatg cattatacag aagataaaga atatatggaa cacgtcggtc
     1021 atttgatcgc tcatcctcgc tttcaaaaat tgagtcatat tgttcagcac caacattcaa
     1081 cgcgtcttga acattctatc aatgtttctt attcaagtta taaattagcc aagcgattcg
     1141 gttgggatgc taaaagtaca gccagagggg gcttacttca tgatttcttt tattatgatt
     1201 ggcgcgtgac caagtttaat aagggtcatg cctgggttca tcctcgtatt gctgtacgaa
     1261 atgcgaaaaa gttaacagaa ctcaataaaa aagaagagga tatcattcta aaacacatgt
     1321 ggggagcgac cattgctttt ccgcgttaca aggaaagtta tattgtgaca atggtagata
     1381 aatactgggc tgtcaaggaa gcagtgacgc ctttgagaca aaaatggtct aatcgacggt
     1441 ttcttcgccg caagaccctc caaagtcata atcgttaagt aaaggagtta ttatgaacga
     1501 tcacgttatt tatacacaat cagatgtggg attaaatcag ttttttgcta aaatttatag
     1561 tctagtggga atgggagtgg gtttgtctgc ttttgtttct tatttgatgc tttatccatt
     1621 tagagaaaat ttaatctcta ttcttgttaa tcagccgatg atttactatg gtgctgcgat
     1681 tattgaactt attttagttt ttgtagccag tagtgcagca cgaaaaaaca caccagctgc
     1741 attgcccatt tttcttatct attctgcgct aaatggcttt accctaagct ttattattgt
     1801 ggcatacgct caaacgacag tttttcaagc atttctttct tcagcagctg tgttttttgc
     1861 catgtcaatc attggtgtca agactaaacg ggatatgtca ggtcttagaa aggctatgtt
     1921 tgctgctttg attggtgttg ttgtggctag tctgattaat ctttttattg gtagtgggat
     1981 gatgagttat gtcattagtg tgatttccgt gctaattttc tcaggtctca tcgcatcaga
     2041 taatcaaatg attaagcgcg tttatcaagc aacaaatggc caggttggtg atggctgggc
     2101 tgttgctatg gccttaagct tgtatttaga ttttattaac ttatttatca gccttcttcg
     2161 tatttttgga agaaatgatt aacattaaaa agtgagtata actactcact ttttaatgtt
     2221 aacaggataa gtaaactgta aggaagaaat tcgagataga tataagatga ggctgctaaa
     2281 agacctagtg ttaatttgta aactctttct ttttttggta tactattaag gattaaatac
     2341 gaggagaata tagatagata tgtcaacagc tatttggatt ttattactta ttgttgccct
     2401 tggggtaggt gtttttggtg ggatttttat tgcccgtaaa caaattgaaa aagaaattgg
     2461 tgaacaccca cgtttaacac cagaagctat ccgtgaaatg atgagccaga tggggcaaaa
     2521 accaagtgaa gcaaaaatcc aacaaactta tcgtaatatc atcaaacaat caaaagcagc
     2581 cgtatccaaa ggcaaaaaat aaaagctaat tgttataggg gaaacctttg tgatagttag
     2641 aagtgaacag tctttgatct caatgttcag tagcacttgt cttatcagtt agatttgtca
     2701 actgttcagg gtttaaaaag aaactcagtt ggctatttcc aactgagttt ttcatatcgt
     2761 cagtaaggaa gtaaacataa tggatacaag accaattggg tttttagatt ctggtgtggg
     2821 aggtctgacc gtcgtttgtg aattgattcg tcagctccct catgagaaga ttgtatatat
     2881 tggtgattca gcaagagccc cctatggtcc tagacccaaa aaacaaatta aggagtatac
     2941 ttgggagcta gtcaattttt tgctgactca aaatgttaaa atgattgttt ttgcatgcaa
     3001 taccgcaaca gcggtggctt gggaagaagt aaaagcagct ttagatattc ctgttttagg
     3061 agttgtctta ccgggggcaa gcgcagctat taaatcaacg acaaaaggcc aggttggggt
     3121 catcggaacc ccaatgacag tggcttcaga catttatcgc aaaaaaatcc agctattagc
     3181 accatctatt caagtaagga gtcttgcttg cccgaagttt gtaccgattg tggaatcaaa
     3241 tgagatgtgt tcgagtatag ctaaaaaaat agtttatgac agtctagcac cattagtcgg
     3301 taaaatagat acccttgtac taggatgtac tcactatccc ttgttacgac caattatcca
     3361 aaatgttatg gggccatctg ttaagctgat tgacagtgga gcagaatgcg tccgagatat
     3421 ctctgtctta ttaaactatt ttgacattaa cggtaattat catcaaaaag ctgtcgaaca
     3481 ccgctttttt acaacagcaa atcctgagat ttttcaagaa attgcctcga tttggctgaa
     3541 acaaaaaata aatgtggagc atgtcacctt atgagtgaaa aaatttacga atacaaagat
     3601 gaaaataact ggtttatcgg aaagatgact ggtcataatt taatatcggg ctggggagtc
     3661 aaacacacga caatcaaaaa aatagatgac cttttagacg gtattgccgc aacgttagat
     3721 tgggaaaatc ctaaaggtta cgatgtttcg gtggtgcgtc atcagtctcc tttatctctc
     3781 atcaccttta ttatcgacat gataaatcaa gagacccagc gtgagattaa ggtaactccc
     3841 catgcaggca cgattttatt aatggaaaat gcgaaactgc ttgcagttta tctcccagaa
     3901 ggtggagttt caacggctac attttttgcg actagtgaac agggatttgg ggatattatt
     3961 ttaatcgcta cacgaaacga gggaaaaacc aaagagttcc gcaatctgtt tggccagcta
     4021 ggttatcgtg tggaaaatct taatgattat ccagaattgc cagaagtagc agaaactggt
     4081 actacttttg aagaaaatgc tcgcttgaaa gcagaaacga tttcacgcct cacaggaaaa
     4141 atggtattag cagacgattc aggactaaaa gttgatgcct tgggtggttt acctggtgtt
     4201 tggtcagctc gtttctcagg accagatgcc acagatgcca agaataatgc caaactctta
     4261 cacgaattag ctatggtgtt tgaccaaaag aagcgctcag ctcaatttca tacgactttg
     4321 gtagtggctg ctcccaataa agatagtttg gttgtggaag ccgattggcc aggctatatt
     4381 gctacgcagc ctaagggaga aaatggtttt gggtatgatc ctgtctttat cgtcggagag
     4441 actgggcatc atgctgcaga attagaggct gaccaaaaaa atcagttgtc gcatagaggt
     4501 caagcagttc gaaaattaat ggaggtcttt ccagcatggc aagcaaaaca atcatagtaa
     4561 tgagtgactc tcatggtgac cgagatatcg ttcaagccat taaagacaag tatcttggtc
     4621 aagttgatgc tattttccat aatggggatt ctgaattaaa cagctcagat cctatttggg
     4681 ctggtattta tgtcgttggc ggtaattgtg actatgatac aggttaccct gatcgtttag
     4741 taactcaatt aggcacagtt acgattgccc agacacatgg tcacttgtac catattaatt
     4801 tcacttggga taaactggac tactttgctc aagaagtagt agcagatatt tgtctatatg
     4861 gacacctaca ccgtccagct gcttggcaag ttgggcaaac cctctttatg aatcccggat
     4921 cagtaacaca acctcgcgga gaaattaacg agaaattata tgctcgtgtt gaactaactg
     4981 atactcaaat taaagttgat tactttacca gagatcataa actttaccca tcactgtcta
     5041 aggaatttaa acgatgatcg caaaagaatt tgaaacattt ttaatgagtc atttagataa
     5101 ttatcttatc ccggaacaag acttggctat ttttatcgac acacataatg cagaccatgt
     5161 gatgttacta ttggtgagca atggtttttc tagagttcct gttatcacac gggagaaaaa
     5221 atatgtggga accattagca tctcagatat tatgatgtac caatctaaaa ggcagctgac
     5281 agattgggaa atgagtcaaa cagatattgg cgagatggtt aataccaaaa ttgaaaccat
     5341 tagcattact tctagcctaa cagaaattat gcacaagtta attgatttcc cattcttacc
     5401 ggttgtagat agagcgaatc gctttgttgg gattattacg cgaaaatcta tattaaaggc
     5461 tgtcaacagt cttttacatg attttacaga tgattacacg attataaaaa aatgaagagt
     5521 tatattgaac cttttattgc tagcaaggct ttatctcaaa atagtcaaaa agcttatcga
     5581 tacgatttgc aacagttttg tcaactgatt ggtgaacgtg tcaatcaaga caaactatta
     5641 ctttatcaaa atagcatagc taacctaagt ttatctgcaa aaaaacgcaa attatcaaca
     5701 gctaatcaat tcttatatta cttgtatcaa ataaagtatt taaatagcta ttttcgatta
     5761 acagacacca tgaaagtgat gcggactgag aagcagcaag ctgctattat taatactgat
     5821 attttctatc aaaaaacccc ttttgtgtgg gggcaattaa tcagcttatt aatattggag
     5881 ctgggtttaa ctccgagtga agtagctggt attgaagtag ctaacttgga tttaaatttt
     5941 caaatgttga cgctaaagac taaaaaaggt gtgcgtgtat tacctttatc gcaaatacta
     6001 atcccttttt tagaacaaca actcgttggc aaagaagtct atctttttga acatcgaggc
     6061 atcccttttt caagacaatg gttttttaat cacctaaaaa cctttgttcg aagtattggt
     6121 tatgaaggat tgactgctca aaaattacga gagcaattta ttttgaaaga aaaactagct
     6181 ggtaaatcga taatagaact tagcgatatt cttgggctga aaagccctat gaccttagaa
     6241 aaatactaca aatcataatg gatataaaac ttaaagattt tgaaggtcct cttgatttac
     6301 tcttacactt ggtatcacag tacaaagttg acatctacga ggttcctatt gttgaggtta
     6361 ttgagcagta ccttaattat attgaaacct tacaggtaat gaaacttgaa gtggctggtg
     6421 actacatgct gatggcaagt cagctcatgt taatcaaaag tagaaggcta ttaccaaagg
     6481 tggtagaaca catcgaagaa gatttagaac aagatctgtt agaaaagatc gaagaatata
     6541 gtcgctttaa agcagttagt caagcgttag cgaagcaaca tgaccaaagg gcaaaatggt
     6601 attcaaaacc taaacaagaa ttaatttttg aagatgctat cttacaggaa gataaaacgg
     6661 tgatggatct atttctagct ttttcaaaca taatggcagc taaaagagca gttttaaaaa
     6721 acaaccatac agtcatcgag cgtgatgatt ataagattga agacatgatg gcttctatta
     6781 aacagcgact ggaaaaagaa aacgttatta gattatcagc gatttttgag gaatgccaaa
     6841 cattaaatga agttatcagt atatttttag ctagtctaga attgattaag cttcacgtgg
     6901 tatttgtaga gcagctctct aattttgggg ctatcatact acgaaaggag aagaaatgac
     6961 gtatttgtca cagatagaag cgctgctatt tgttgcaggt gaagaaggat taagtttgcg
     7021 acatctagcg tctatgttat cattaacgcc aacagctctt caacagcaat tagaaaaact
     7081 ctctcaaaag tatgaaaaag atcaacattc tagtctttgc ttgatagaaa cagctaatac
     7141 ctacaggcta gtaactaaag aaggttttgc agaactcttg cgtgcttatg ccaaaacacc
     7201 aatgaaccaa agtttatctc gtgcgagttt agaggtcttg tctattgttg catacaaaca
     7261 acctattaca cgaatagaaa ttgatgacat tcgaggggta aactccagtg gagctttgag
     7321 taaattattg gcatttgatc tcattagaga agctggcaaa aaagatgtgg ttgggcgtcc
     7381 tcatttgtat gcgacaacag attattttct ggactatatg ggaattaatc atttagacga
     7441 attgattgaa gtatctgccg ttgaaccagc agatgaagag attgctcttt ttaggacaca
     7501 agactgagtt ttgcttgtca tcaaatagca aatggcgttt acaaaaggat ttgttttaag
     7561 gcgttttagt tgaaaaaaaa gccttaaact agggacaaca aaaagttgct caaaagaaag
     7621 aagaatataa tgcgaattaa caaatacatt gcccatgcgg gtattgccag tcgtcgtaag
     7681 gctgaagaat tgattaagca aggcttagta accttaaatg gtcaggttat tacggattta
     7741 gcaaccactg taaaatcggg agacgtggtt gaaatagaag gaagtcctat ttacaacgag
     7801 gaaaaggttt actatttgct taataaacct cgtggcgcta tctcaagtgt gtcagatgac
     7861 aaaggccgta aaacggtact ggatttacta cctcaggtta aagaacgcat ataccctgtt
     7921 ggacgattgg attgggacac atcaggggtc cttattttaa cgaatgatgg tgattttaca
     7981 gatactatga ttcatcctag aaatgaaata gacaaggttt atctggcgcg tgtcaaaggt
     8041 attgcaacga aagaaaatct tcgtccctta actcgaggaa ttgttattga tggtaaaaag
     8101 accaaaccag ctcgctacaa tattgttcgt gtagaagctg ataagagtcg atcgatcgta
     8161 gaattgacta tccatgaagg gcgaaaccat caagtgaaaa aaatgtttga gtctgtgggg
     8221 cttctggttg ataaattatc tcgtacacgt tttgggaccg tcgacttaaa gggactaaga
     8281 ccaggagaag caagacgctt aaataaaaaa gaaataagtc aactgcataa cttagctaat
     8341 acgaaaaaat gatgaaaaaa ctattaatag tatctgttaa agcttatcaa aaatacattt
     8401 ctcctttatc tcctcctagt tgtcgctaca agccaacctg ttcagcttat atgttaactg
     8461 ctattgaaaa acatggtact aagggaatat taatggggat agcaagaata ttaagatgtc
     8521 acccttttgt tgctggtggt gtcgatcctg ttccagaaga ttttagccta atgagaaata
     8581 aaaacacgtc taaaaacgct gaaaaggcat gactttatca aaaaatggct tgacattgat
     8641 agctgaagtg ttataatgga aaataagcat tcgttggttt aaatcaaacc tgttatgatt
     8701 taagttagcg agtcaccatc aaccacattg tttgctgagc atgactccga gcagtgtggt
     8761 tttttaaatt aaaaagagta aatgagatta tgacgacaaa agaacttatc aacaaaaacg
     8821 acaaagtaaa aaaggctcgc aatcatattg tcctgtttca accccaaatt ccacaaaata
     8881 ctggtaatat tgctagaaca tgtgctgcaa ctaatgcacc tttacatatt attaaaccca
     8941 tgggatttcc tattgatgac cgcaaaatga agcgtgcagg cttggattac tgggacaagt
     9001 tagaactgca tttttatgat catttagaac agtttatcaa tcaatgtcac ggacagcttc
     9061 acctgattag caagtttgca gttaataatt attctcaagc tacttatgct gatggcgatt
     9121 cccattattt cttgtttgga cgagaagata caggcctgcc agaagatttt atgcgagaac
     9181 atgctgaaaa agcacttcgt attccgatga atgatgagca tgtacggagt ttaaatgtct
     9241 caaatacggt ttgtatggtg atttatgaag cccttagaca acagggcttt caagggttag
     9301 agttaaagca tacttacgaa cacgataaac taaaataatg gactttttaa aagcgtcagt
     9361 ttttggcaac atgcgttgtc agtagctgac gcttttaaaa atttagtcaa agctattgct
     9421 atctaggttt aaatctgcta tgctagaagt gtcttcaggg cagggtgtga ttcccgaccg
     9481 gcggtgacta gtaactagaa gtccgcgagc gcaagctgat gtggtgtaac tccacaaccg
     9541 acagtatagt ctggatgaga gaagaccggg ctttttgtgt aggcttattt tagctacaca
     9601 ataacgacgg aacttctttc aatttgaaaa aattggagga attttttaat gtcaaaaaca
     9661 cataaaatga ttatgattgg tatactttct gcgatatcat ttctattgat gctagttagc
     9721 tttgccatta ttccaggcgc agctttttta aaaattgaat ttagtattat tcctgtttta
     9781 tttggtttaa tgattatgga cttaaagagt gcttacttaa ttttgttatt gaggtcctta
     9841 ttgaaactct ttttgaacaa tcgtggggtt aatgatttta ttggtctccc aatgaatatt
     9901 atcgctatcg ctttatttgt gacggctttt gccttagttt ggaaccgtca aaaaacgctt
     9961 agtcaatatg tatttgctag cttactaggc acagggttat taacgtttgg catggttgtt
    10021 cttaattata cttttgccat tcctttatat gctatatttg caaatattga tatcagagct
    10081 tatattggtg ttactaagta tatgatgact atggttattc cgtttaatct tgttgaaggg
    10141 ttgatatttg caattacctt ttattttgtg tatattgcaa gtaaaccaat tttagaaaga
    10201 tacttacact aatatgatga caaacaaaca aactcacttt ttaatagctt cttttgcatt
    10261 gctaatcttt gttataatag gctatacggt caaatttttt cctgaacgtt tggcacttct
    10321 agataatact attcaagcag agattagagg caaccttcct atagtgctga cgcaattctt
    10381 taggggtgtt actgtatttg gaaatgtcat gacacaagtt ttgttagtta ttgtgtcggt
    10441 cctagtttta ttctttatga agtggaaaat tgaagccttg tttatcttgt caaatggtgc
    10501 cattgcagca tttttgatta cgactctcaa gctcttttac caaagaccaa gacctgctat
    10561 tgagcatttg gtttatgctg gtggctattc gtttcccagt ggccatgcga tgggtagcat
    10621 gctgattttt ggtagcctat tgattatttg ttatcagagg ctacattcaa aactattaca
    10681 atttgtgact agcatgatct ttataatact aattttatta attgggttat ctcgtattta
    10741 tctaggagta cactacccaa gtgatatttt agcaggcttt gtattaggat ttggtatttt
    10801 gcactttatt tatccttttt ataagcaaaa acgatttgaa tggcgatttc ttttgaaaca
    10861 agactaattt ttcttgagaa gacataggct tatttaaatc atttagaata acattggcaa
    10921 gcatcacccc cttgattgcc agtgttattt tagttttagt tagatgatgt gagctgatga
    10981 ttagtaaata tgtttagata aaaaacgatt aaagtgctat gtaacgtcag aaaagacgtg
    11041 atttttgttg atctgtaatc attaagtaag ctgatgtaga agtagtgaat tctaatgact
    11101 gagctatctt ttgcatagat gactatcttg ctagtaatga tttgtgctac aatagaaaca
    11161 tgaaaaaaag atatcagaca ttaaatgagc attaccgtca actatttggc gcaaaaatgt
    11221 ttaaagttcc gattgatgcc ggctttgatt gtcccaatcg tgatggaacg gtagctcatg
    11281 gaggatgtac tttttgcaca gtatcaggtt ctggagatgc tattgtagca ccagatgctc
    11341 caattaaaga gcaattttat aaagaaattg attttatgca ccgtaaatgg cctgatgtca
    11401 atcgctattt ggtttatttt caaaacttta ccaatactca tgatacagtt gatgtgattc
    11461 gcgaccgtta cgaacaagct attaacgaac ctggagttgt tggtattaat attggcacac
    11521 ggcctgactg tctaccagat gataccattg cttacttagc agaattatca gaacgcatgc
    11581 atgtgacagt ggagctaggc ttacagacaa cttatgaaga aacttctagg ctaattaaca
    11641 gagcacattc ttatgatttg tataaagaaa cggtgaggcg actaaggcat taccccaaca
    11701 ttaatattgt ctcgcacttg attaatggat tgccaaaaga aactcatgac atgatgcttg
    11761 aaaatgtgag acgctgtgta acagacaatg acattcaagg aattaaattg catttgctgc
    11821 atttgatgac caatactaga atgcaaagag attatcatga aggacgctta aagttgttga
    11881 gtcaaaagga ctatgtttcg attatttgtg accagctaga gattatccct aagcatattg
    11941 tgattcaccg tattacagga gatgccccac gcgatatgtt gattgggccc atgtggagtc
    12001 taaataagtg ggaagtattg aatgccattg ataaagaaat ggaaagacga ggaagctttc
    12061 agggctgtaa agttgactaa tttgtctcat tttgacggat ttggatagga gaaaagtgat
    12121 gctaaaacgc cccattcatc tctcgcatga ttttttagcg gaggttgtgg ataagtctag
    12181 tgtggttgtt gatgccacga tgggtaatgg aaatgatact gcctttttgg cacaattagc
    12241 taaaaaggtt tatgcttttg atgtgcaaga acaagctatt agaaaaacaa gtgagcggtt
    12301 agcgcagcta ggattatcga acgctgagct gattttagcg ggtcatgaag cggttgatca
    12361 gtatgtgaca gagccggtgc gcgcagcgat ttttaacctt ggttatttgc ccagcgcaga
    12421 taaatctatt attaccttac caaataccac actccaagct ttatcaaaac tactaacgtt
    12481 attaatggta ggtgggcgta ttgctattat ggtctattat gggcatgatg gaggcagttt
    12541 ggaaaaagat gctttattag attttgtcaa gcaattagac caaagaaagg tttctgcaat
    12601 gctttatcag cctcttaatc aggtgaatac cccacctttt ttaatcatgt tggagaaatt
    12661 agcagacttt tagctcttat ccctgtgtca agtctactag aagttctgcg attatttcgg
    12721 tggaaaaaga agaaatccca taggctttgg ctataaatgt gatataatga agtcactata
    12781 ttattttttt aggagttaca ttaacatgga agaccctgtg agtcagccct tagtgattca
    12841 atttttattg ttagttgttt taaccttgtt aaatgctttt ttttcagcca gtgaaatggc
    12901 cttagtttct ctcaatcgtt ctcgggtgga acaaaaagca gcagacggtg ataaaaaata
    12961 cgctcgtttg ttgcgggttt tagaggaacc taatcatttt ttatcaacga ttcaagttgg
    13021 gattaccttt attagtttac tatcaggagc aagtttatca gcttctttgg gtaaggtgat
    13081 ctcaggttgg ctaggtaatt cagcgaccgc aaggacagct ggtactatca tctccttggt
    13141 tttcttgact tatgtctcta ttgttttagg agaattgtat ccaaaacgga ttgccatgaa
    13201 cctcaaagac aagttggcga ttgtttcagc ccctattatc attgggttag ggagactggt
    13261 tagtcccttt gtatggctct tatcagcttc tactaattta ctgagccgac ttacccctat
    13321 gacctttgat gatgcagatg agcaaatgac acgtgatgaa atcgagtata tgttatcaaa
    13381 aagtgaggcg acccttgatg ctgaagaaat tgagatgttg caaggagttt tctcacttga
    13441 tgaaatgatg gcgcgtgaag tcatggtccc aaggaccgat gctttcatga ttgacattaa
    13501 cgatgatccg cttgaaaata ttcaggaaat cttaaaacaa agtttttcac gcattcctgt
    13561 ttatgatgtg gataaagata aaattatcgg tctcatccac actaagcgtc tcttggagtc
    13621 aggtttccgc cagggatttg atcagattaa catgcgaaaa atgttacaag aacctctttt
    13681 tgttcccgaa accatttttg tagatgatct cttacgccag ctgcgcaata cccaaaatca
    13741 gatggctatt ttgctagatg aatatggtgg tgtggcagga cttgtgactt tggaagactt
    13801 gcttgaagaa atcgtcggtg aaatcgatga tgaaaccgat aaagcagaac aatttgttca
    13861 tgagattgga gacaatacct atattgttgt tggtactatg actttaaatg agtttaatga
    13921 ctattttgat accgaactag aatcagatga tgtagatacc attgctggtt tttatttgac
    13981 aggtatcgga accattccaa gccaggagca aaaagaagcc tacgaaatag ataacaaaga
    14041 caaacattta gttctaatca acgataaagt caaagatggc cgtattacga aattaaaatt
    14101 aatcctgtct aatatagaac agattattga ggaagactag gctccatgcc tagtcttttt
    14161 gatgaaaagt gttataatga aaatgtaaaa acgtttacaa gtaatgaagg agatgcaatg
    14221 actgagaaag attatggaca agtaacaggg atggtgcatt cgacagaaag ttttggttct
    14281 gtagatggtc caggcattcg ttttatcatt ttcttgcaag gctgtaaatt acgttgccaa
    14341 tattgccata atccggatac ttgggagatg gaaaccaaca attcaaaaat cagaacagtc
    14401 aatgatgtct tgaaagaagc ccttcagtac aaacatttct ggggaaaaaa aggaggaatt
    14461 accgtatctg gtggtgaagc tatgcttcaa attgatttta tcactgcctt attcatcgaa
    14521 gctaaaaaat taggtatcca taccacacta gacacctgtg gctttaccta tagaccgaca
    14581 cctgaatacc atcaggttct tgataactta ttggcagtga ccgatttgat tttattggac
    14641 ttaaaagaaa ttgatgaaaa acaacataaa attgtcacgc gtcagcctaa taaaaacata
    14701 ttgcaatttg ctaggtattt atccgacaag cagattcctg tctggattcg acatgtcttg
    14761 gttccaggct tgactgatat tgatgatcat ttgacacgat tgggtgagtt tgtcaaaacc
    14821 ttgaaaaatg tcgataaatt tgaagttttg ccttaccata ccatgggaga attcaagtgg
    14881 cgtgagctag gtattcctta tcagttagaa ggtgttaaac caccaactaa ggaacgcgtt
    14941 caaaatgcta aaaatctgat gcagaccgaa tcttacacag aatatatgaa tcggattcat
    15001 cagtcataag agctgttata gggttgaggt ttcttcaact ttttaaagta ttataagcag
    15061 atcttttgta atcttccttt gattttaggg ggtaattttg ctaaaataaa atgaataaac
    15121 aaaatgaggt agaatgatta tgtcaaaaat tttagttttt ggtcatcaaa atcctgatac
    15181 ggatgctatt gcatcatctt atgcttttga ttacttatcc caaaaagcgt ttggtttgga
    15241 tactgaagtc gtagctttag gaacacctaa cgaagaaaca gcttttgccc ttgattattt
    15301 tggtgttgag gcaccacgtg tggtagagtc tgctaaagca caagggtctg aacaagtgat
    15361 tttgacagac cacaatgaat tccaacaatc cattgcagat atccgtgagg ttgaggtata
    15421 tggtgtggtt gatcaccacc gtgtggctaa ttttgaaact gcaaatcctt tatacatgcg
    15481 tgtggaacca gtaggatcag cctcatctat tgtttaccgt atgtttaaag aaaatggcat
    15541 cgaggtgcca aaagcgattg cagggatgct cttgtctggt ttgatttcag ataccttgtt
    15601 gttgaaatct ccaacaactc atgtgtctga tcaccttgtc gctgaagaat tggcagagct
    15661 agcagaagtg aacttggaag actatggaat ggctctttta aaagcaggta caaaccttgc
    15721 aagcaaatca gaagtagaat tgattggtat tgatgccaaa acatttgaat taaatggcaa
    15781 tgctgtgcgc gtggcacaag tgaacactgt tgacattgca gaagtcttag aacgtcaaga
    15841 agctattgaa gcagccatta aagatgccat ggctgcagaa ggttattcag attttgtttt
    15901 gatgatcacg gatattgtta actcaaactc tgaaattcta gctattggag caaacatgga
    15961 caaggttgaa gcagccttta acttcaccct tgacaacaat catgccttct tagcaggtgc
    16021 cgtttctcgt aaaaaacaag tggttccaca attgacagaa agttttggag cttaatgaaa
    16081 agacgcttta aaaggacttg atttttttga ccaagtcctt ttgtcactct tctatgttat
    16141 aatagaaggt atgataacag tatttcattc agataaactc accagacaac ctttctttca
    16201 agaccttatc aattatctcg accagcatga tcacgttata ttacgagaga tcaaaaaagc
    16261 ctttcctaat gtgacaggta ttgacaaggc catcgaaagc tatgttcaag ctggctatat
    16321 tcgccgtgaa aataagcgtt atggcatcaa tcttcctttg gtgagttctg atcagcagct
    16381 ggccttagac actatgcttt ttgtggacac ctgttcagct atgtatgaaa atattttagc
    16441 ggttgttttt gagactcagc taacaaacca aaccaatcgc gtgatgatca aggaaaagac
    16501 caacatcacg agagacgatt tgaccctggc taattatttt taccgtctca aaagaggtga
    16561 gaagccatca gctgagcaga tggacttgta tgacctcttg ggggatgtga atcaggaata
    16621 tgcccttaaa tatatgacaa cttttttgct taaattcacg cgcaaagact ttgtgatgca
    16681 aaaacgtcct gatatatttg tggaagctct ggttacactt ggttacctaa aacaagtgga
    16741 gcctacaaca taccagctgc taatgacctt ggataaagaa agtttaacct ttatagcacc
    16801 atagaaaaga gctaggaaca aggactgttc ttagcttttt gagtgctttt attttgtttt
    16861 tgccattaag taaagaaaat aaggggctcc gataagcgac actaaaatcc ctgtctggat
    16921 attactgcca accagataga ctcgtcctac tgtatctgca acaagaagta ggatcattcc
    16981 gattaaaata ctaatgggta ttgttatttt atgattactc cctaccaagt atgtactaaa
    17041 gtgtccagct attaagccga taaaactaat attaccaacc aaaagaacac tcaaagcacc
    17101 taagccagct gctaagacaa gtatcaaacg acgcttacgg tttaaaggga gtcctagccc
    17161 aatagcagta ttatcagcta atcccataat attaaggaaa tgggcttgac tataagtcaa
    17221 tagccaaaaa cacaataaca aaggagcgat gacactcaga gtaggccagt cgtctcctat
    17281 caattggccg ctaagccaat tgatgaccaa atcgactttg tagcgattaa tatgaccaac
    17341 aagagcaacc attagacttg aaagcatggt agtaacagct acaccagtaa gaattaaccg
    17401 tgtaggatca atttgtcctt gttttgtcaa agatagccaa taaacgctaa aggttgttac
    17461 aatagcacca agcatggcaa ataaaggcaa gtaatggctg atatgagctt gctcaaagaa
    17521 agaaaaggag accacaatag ccaaagagat acctgctcct atagtaatac ctaatacacc
    17581 agagtcagct aagggatttc gtgttaaacg ttgtaataat agccctgata aagcaagaga
    17641 accgcctcct agacaagcag ctagaattct tggcagacga atgttaataa cgatgaaaga
    17701 tatggcatgg ctagattttc ccaaaaacac atggacaagg tccaaaaaag atagatgaga
    17761 ttctccaagg gacaaagcta atcccataag acttacaagt agcaggatca ggctagtata
    17821 taaccttaaa aggtgtcttt gagatttcaa tagcggcctc ctcttcttat taaccataaa
    17881 aagcatggaa aaccaattaa gctaaccaat gccccaagag gggtttcata aggcggattg
    17941 agattacgac aagcaatatc aacccatacc atgaaactag cgccagaaac tgcacaaagc
    18001 ggcaaaaggt atcggtaatg atgaggtgta aaatgtttca taagatgagg aatgactaag
    18061 ccgataaaag aaatgcttcc agcaatggct acagctgctg atgataaaat aagaaccaaa
    18121 atcataaaga ctgcactgat caagttggtt ttttgcccaa gagcttttgc ctgagactca
    18181 cttagactaa ggacggtcag gtgataagat aatagctggg ctaaacaaag actaagaata
    18241 ataagaggag caatatagcc gatcatttgc caattgaccc cgacaagacc tcctgcttgc
    18301 cagccgataa cagcatttgc cagatgatag taattggtaa taccttgacc taatgctgat
    18361 agcagtatgg aaaccatagc tcctgctaag acaaggcgga gctgatggta gcctttgcca
    18421 gattgataag aaaggccaaa gactaaggtt gctgccaggc tagaccctaa caacgaaagc
    18481 agaataatga gggaatagtg caagtgaggt acaaacgcat aagccagtac caaggctagt
    18541 cctgctccag cattaatgcc taaaaggcca ggctcagcga taggattacg tgtgattgct
    18601 tgcatgatag ttccagaaac agctaacgca gagccagtta aggtagcacc aaaaagtctc
    18661 ggtaatcgta tagcgagtaa aacattggct ttatggccgt tttgctttcc aaataaaata
    18721 gagttaagat cctgatgtga taaagcaacg gctccaaagc gcagatgaca gtaaatagca
    18781 acacataagc taaaactaag tagcacaaag acaagccaaa agatatgtga cttagtgatt
    18841 atctgcgttt tttttaagca aaaacgctcg agacacaaaa agggatgctt agttttcact
    18901 tgataagatt gcctctcgta aagtctctaa ttgatattct aaagaaagag gatcagtaaa
    18961 gtaaaaaaca ttggcattga ctttgatcac atggtgtttt ttcacagctg gaatggattg
    19021 ccatagcttg ctttcatata gagcagaacc agtcttatca tcttctgcag caacgacgac
    19081 ataatcacca atatagtctg gcaagacttc ctgcgacaat gacaggtaac cttgtttaaa
    19141 aacttcagtc ttcacttttt caggagcatc ataatggaaa gcttgatgga taatctctcc
    19201 gccacgtccc cagtctttac caaaaaggta aacgtctttt tcataaagcc ccataatagt
    19261 aaaggttgct ttgtcacctg taacggcctt gacttctttt tcataagctg ctgttttagt
    19321 tttccaatct tttaaccact tcttggcttt gtcttctttg ttaaagatgc ggccgaagtc
    19381 agataacact tgtaaataat cacgtttgcg gtattcaatc gagataacag gcgcaatttc
    19441 tgccaattgt ttaatatttt cttctgtaga gccaacaaca atgaggtcag gcttaagcgt
    19501 tgtaacggct tctaaatcag ttgcagcaac ttgctttgct ttttttacag tctttgctaa
    19561 gatggggttt ttcttgtcat aagaagtaac cccgactaga ttcatatcta attttttgag
    19621 gtaaccagtg taagttgaag ccagactgac tactcgctta ggctgtttag gaatatctcc
    19681 gtaataagtc acaccagcaa tttgaggcat aggcgataaa ctttttgagg cggtgttaga
    19741 atgattagtt gcttgattac cacaggcgat taaggtaata gttgtcaaac agagtgttaa
    19801 tagtagagtt aattttttca tgtatgctaa ttctcctaga ataaagttat tgaagctgat
    19861 aagtcagcac tataggacag ttgtggatag gatcatcaac cagtaccggt ttgatttgga
    19921 agatgtcttg aatgataggt gaagtcataa catctgctat agtaccagta taatggatct
    19981 tgccatgttt catagcaatc agatgatccg aatagcgggc tgaaagattg aggtcgtgaa
    20041 gaaccataac aatagtcttg ccggcatcct tatttaggga tttaacgagc tctaggattt
    20101 ctagttgatg atttaaatct aaataagtag ttggctcatc taaaaaaata gtatcagtgc
    20161 cttgggctaa tgccattgca agccaaaccc tttgacgttg ccccccagaa agagcatcaa
    20221 caggttgatc agcataggcc atgacattgg tggcttgcat agcccaatga atggcttttt
    20281 tgtcagctgg actaagattt ccaaagtaag attgatgggg aaaacgtccg taagaaacca
    20341 attcgtaaac agttatgccg ttagttgctt cttgaacttg aggtaaaaga gctagttttt
    20401 tagcaacctc tttagtttct aatgtggcaa tgttttgccc atttaaatat acaactccct
    20461 gttttggtgg taataatctt gtcagtgctt ttaataaact agacttccca cagccattgg
    20521 cgccaataat ggtcgtaatt ttaccttcag gaatataaaa cgataattta tcgatgatgg
    20581 tacgctgttc ataggcaatt gtgaggtctt cagcactaat tgttgtcata tggttgcctc
    20641 ctttctaaaa agagtcaaag ggttgatgaa agtgcacatt aaagtgttca tctgcccatt
    20701 ttaaaatagt tgagaagtag cttattttct caaaatcttc actattatag catagaaaaa
    20761 aggcttaaca aagccttttt tgatgtgatt tttaggatgt attaaaaaag aaatattagt
    20821 ttagaatgat taaaaacaat agcgataatc attctaaact aacgtcaaca tactctagag
    20881 gtagtgtttg gcgattgcta aatcaccagc ataagctact tgttgtcctt taacaatttg
    20941 ataagcatct gcgcctttcc cagcgataat cacagcatct tttgctcctt ggcaaagaga
    21001 catggctttt tgaatagctt gctcacggtc actaataatc tctactgggc gtgcgatatg
    21061 gctggcaatt tcttttgaaa tatcttctgg atcctcgaaa ttagggtcat cagcagtgag
    21121 aatgacggtg aggtttggat gctgatgaat caccctacca aaatcagctc gtctgctctc
    21181 gcctttattt cctggtgcac ctaaaatcaa cattaatttg cctgtctgat gttcttccac
    21241 aacgctgagt aatttttcta agctgtcacc attatgggca taatcaacaa aaactttagc
    21301 atgatttgtc atagtgagga cttccatacg gcctgggacg cgagtcttag cgataccttt
    21361 ttgaatatca gctaggctag cacccaaacg aaggcaggca agtccagctg ccatagcatt
    21421 ttcttggtta aaatggccaa ttaattgaat gtcataatgg ccagctaatt gtcctttagc
    21481 ttcaaaggag aaggcttggc tagtggtgat ctggttgtca gacaagggac cataaaacac
    21541 atgctcttga tccgctacct gatccgctag aaatgaaaaa tgatccatcc cgctattgat
    21601 cacaacagct ctgctattct ccattaaaag acgcttatga tagaaataat cttcaaacgt
    21661 tggatgctcg attgggccaa tatgatcagg actaatattt aggaaaaccc caacatcgaa
    21721 cgtaagccca tagacacggt caacgaggta agcctgacta gaaacttcca taatcaagtg
    21781 ggtcatgcca ttagtcacac actcagccat catagcaaaa agatccaagc tctcaggagt
    21841 tgtgagttgt gatttgaaaa aggtcttgcc atctaaggtg gtattcatgg tagaaaacat
    21901 ggcaggttta taggattctt tcaacatgtg gtaggcaaaa taagcagccg tcgtctttcc
    21961 cttagtacct gtaaaagcta gtagtttgag cttttcttga gggttgccat agaaagccat
    22021 ggcaattaga ctcatagctt ttttgatatc agtgaccaaa acaacgggaa taccaagctc
    22081 gtaatctacc tctgaaatat agagttgtaa tccgttagtg attgcttctt taaggtagtc
    22141 agctttgaaa gttgcccctt tagcaaaaaa aagggtcttg ccatctactt gacggctatc
    22201 gtaactcaag cgctcaaaac taaagccttg ataatggtag tggtatccgt cggcatcaag
    22261 aacctcacga aaattatggt ctttttttaa aatgtctaat aattgttcaa tggttatcat
    22321 acccttattt tatccttaaa gttcttgttt tacaagtcac aagcaaaagt ttataataaa
    22381 gctaatagaa actaggaaag aatagatatg tcgacagaaa aaaaacaact gacacaagaa
    22441 gaattgatgg ttcagggagc agcctggtcc acagctggta atttcattag ccgacttttg
    22501 ggagtgttat acattattcc ctggtacatt tggatggggc aatacgcgat tcaagccaac
    22561 gctcttttca atatggggta taatgtttat gcttattttt tattgatttc aaccacagga
    22621 ctcaatgttg cgattgctaa gcaggttgcc aagtacaatt ccatgggaca aactgagcat
    22681 agctatcaat taatccgaag taccctaaaa ctcatgcttg gtctgggcct tattttttca
    22741 gccattatgt atctgggctc tcctttattt gcgagcttat ctggtggtga tgacacactt
    22801 gttcccatta tgcacagcct ttctttagca gtttttattt ttcctgtaat gagtgtgatt
    22861 cgaggcatct ttcaaggcca caataatatc aagccttatg cagttagtca gattgctgag
    22921 caactcattc gggttatctg gatgcttttg accacctttt ttatcatgaa gttgggttct
    22981 ggtgattacg cttcagcagt gactcagtca acttttgcag cctttatcgg gatggtggct
    23041 agtatgggtg ttctggggta ctatctttgg aaacagggac ttctagcagc tatttttagt
    23101 aagccagatc atactgtttc tattgatatc aagggcttgt tgcttgaaac cttaaaagaa
    23161 tccatcccct ttatcgtaac aggaagtgcc attcaagcct ttcaattgat tgatcaatgg
    23221 acttttgtca atacgatgac tctttttaca gattatagcc gttctcaatt gcttgtttta
    23281 tttggttact ttaacgcaaa cccagccaaa attacaatgg tcttaattgc agtagcagca
    23341 tctattggtg gtgtaggtat tgccttgtta actgaaaatt atgtcaaaaa agacatgaaa
    23401 gcagctgctc gtttaatcat taacaacatt gaaatgttag tgatgttttt gttacctgct
    23461 cttactgggg caattatttt agcaagacct ctatattctg ttttttacgg agctagcgag
    23521 gagcgtgcca ttcacctctt tgtggcggtt ctctttcaaa ccttgctact ggcgctttac
    23581 accctctttt caccgatgct tcaagctctt tttgaaaatc gaaaagcgat ttactacttt
    23641 gcctatggta tcttgattaa gttagtttta cagataccgc ttatttattt gctacatgct
    23701 tatggtcctt tactagcgac gacgattgct ttagtggtgc cgatttattt gatgtatcga
    23761 cgcctatatc aggttactca ttttaaccgc aaactgttgc aaaaacgttt attattaacc
    23821 ttaattgaaa ccttattaat gggactggtc gtgtttgtgg ccaactggct attgggctat
    23881 gcctttaaac cgacaggccg cttgaccagc cttctttacc tcctcattat tggtggcttg
    23941 ggaatgacgg tttacacggc actcaccttg ctgacgcatc aactggataa attaattggt
    24001 agcaaagcta gtcgccttcg tcagaaatta ggctggcatt aatataatga caccaagaac
    24061 gatttcgtga gtgcttatcg aaatcgtttt tttcttaatg atctcgctta gtaaaggtag
    24121 ctgataaaaa atcaggattt cccaagcaaa ctactgatat ttttggtata atgataaaag
    24181 tgtaaaaaaa tagaaggaag tatatcaaca tgggaaaatg tcaagttatt tcgcatccgc
    24241 ttatccaaca caaactttca atcttacgtc gtcaaaccac atcaactaaa gattttcgtg
    24301 agttggttaa tgaaattgcg atgctgatgg gatatgaagt gtcacgcgac cttcccttag
    24361 aagatgtcga catccaaacg ccagtctcaa aaacggtcca aaaacagtta gctggtaaaa
    24421 aattagctat tgttccgatt cttcgtgctg gtattgggat ggttgatggc ttgttaagtt
    24481 tggtaccagc tgcaaaagtt ggccatatcg gcatgtaccg taatgaagaa acccttgaac
    24541 ctgttgaata cctcgttaaa ctaccagaag atattaacca acgacaaatt ttccttgttg
    24601 atccaatgtt ggcaacaggt ggctcggcta tcttagcagt ggattcgttg aaaaaacgtg
    24661 gcgcagcaaa tattaagttt gtctgtttag ttgcagcacc agaaggggtg aaaaaacttc
    24721 aagaagctca tccagatatt gatatcttca cagcagcact tgatgatcat ttaaatgaac
    24781 atggctatat cgtgccagga ttgggcgatg ctggtgatcg tttatttggg acaaaataaa
    24841 agagacaacc atcaaatagt agccttttta ggccaatcgt tcttgatttt gtttaaaaaa
    24901 tcagagagat ttctcttctt taaaggaaaa gcaagtttat gatttgacct ttattgacca
    24961 aaatattata ataaagacaa tcagtaaaaa agagatgacc tagtgggttg ccgtctctca
    25021 aaatgacgct actaaaaacc cttgtagatt ggagaatgta ttatgattcc tgttgttatt
    25081 gaacaaacta gccgtggaga acgttcttat gacatttatt cacgtttatt aaaagaccgt
    25141 attatcatgt taacagggcc tgtcgaagac aacatggcca actctgtcat agcgcagctc
    25201 ttattccttg acgcgcaaga caacactaaa gatatctacc tatatgtcaa cacaccaggt
    25261 ggctctgtct cagcaggctt ggctattgtc gataccatga actttatcaa ggccgatgtg
    25321 caaactattg tcatgggtat ggcagcttct atggggacag tcattgcttc atcaggaaca
    25381 aaaggcaaac gctttatgtt accaaatgca gagtatatga tccaccagcc aatgggtggt
    25441 acaggtggtg gcacgcaaca aacggatatg gctatcgcag cagaacatct cttaaaaaca
    25501 cgtcaccgtt tagaaaaaat cttagcgcaa aatgctggaa aaacgattaa acaaatccat
    25561 aaagatgctg agcgtgatta ttggatgagt gctgaagaaa ccttggctta cggtttcatt
    25621 gatgaaatca tggaaaacaa cgaactaaaa taaagaggat ctctgcaaaa gtattctaga
    25681 aacttctagg atgctttttc tcttagaaag gaaaataatg atacagccta ctgcattaaa
    25741 acagcttcaa gagttaaaac gtcagttcag atccctttgc aaccaattat gagatagttt
    25801 gaggatgatc cttagcagct gtgtgcaaga agttatgacg atttcataaa ggatgaccta
    25861 gccagtcttt cttcgtctct tttacttaaa gtgtggtata atcagattat gctagccaaa
    25921 actaaaaaag gcattgccat taaaggtgtt gtagatcggc ttatcctaga tctcataaca
    25981 atgctgtagt accaccctta ccttgctact aaaggcgctg ttgaagcaca aattgacttg
    26041 caaaggatct tgactgataa tatgtccggt ggaatcgcca aagcagcaaa aagaccaaga
    26101 cccttatttg gtctctacca aaatataata gaaaaggatt tagaatgttt caaaaacaag
    26161 aacgtattgg actcgtcgtt tacctgtatt ataaccgaga tgccagaaag ttatcaaaat
    26221 ttggtgattt atattaccat tccaagcgct ctcgttacct cattatttat attaataaaa
    26281 atgatttaga cacaaaatta gaagaaatga gacgtttgaa atgtgttaaa gacattagac
    26341 catcagcttt tgatgatatt gaccgccaat ttgtaggtaa ccttcatcgc gacgaaacaa
    26401 acaaccatca aaagggttaa caacccccta gttactgatt agcgtttcag atttagttag
    26461 cttattaaag taagaaggtt ttgacagatg ctcacactac ttcaagacaa tgagacaact
    26521 agagcattag tgaataactg agttgactgt cacttcttta ataagaacgg ataggattgg
    26581 tcctaaaata gagcactgca aagatatgcc agtgcttttt agctcatttt ttgataaaat
    26641 agaactacta aaaagtgaag gaaataagat gatcacagga aaactcataa ccgttgaagg
    26701 tccagatggc gcagggaaaa cgactgtttt agagcaactc attccactgt taaaacaaaa
    26761 agtggctcag gatatcttga caacaagaga gcctggaggt gttgccattt cagaacacat
    26821 tagagaactt attttagaca tcaaccatac tgctatggac cctaaaacag aactcttact
    26881 ttatattgcg gctcgaaggc agcatttggt ggaaaaggta ctaccagctc ttgaagcagg
    26941 ccagttggtt tttattgatc gtttcatcga tagttcagta gcttatcaag gtgcgggacg
    27001 cggtttgatc aaagcagaca ttcagtggct caacgagttc gcaacagatg gtttagagcc
    27061 tgacttgacc ctttattttg atgttccttc tgaaattggt ttagcacgga ttaacgcgaa
    27121 ccaacaaaga gaagtcaatc gtttagattt ggaaacaata gagatacatc aacgagtacg
    27181 aaaaggatac ctagccttag ctaaggagca tccaaaacgt attgtcacaa ttgatgcgac
    27241 taaaccattg aaagaagttg tctctgtcgc tttggaacat gtcttagcct tgcttttagc
    27301 ctaggataag ggagggtagg aatggattta gcgcaaaaag ctcctaacgt ttatcaagct
    27361 tttcagacaa ttttaaagaa agaccgtctg aatcatgttt atcttttttc gggtgatttt
    27421 gctaatgaag aaatggctct ttttttagct aaggtcatct tttgtgaaca gaaaaaggat
    27481 cagacgccct gcgggcattg tcgctcttgt caattgattg aacaaggaga ttttgccgat
    27541 gtgacggtat tggaaccaac agggcaagtg attaaaacgg atgtggtcaa agaaatgatg
    27601 gctaactttt ctcagacagg atatgaaaac aaacgacaag tttttattat caaagattgt
    27661 gacaaaatgc atatcaatgc cgctaatagc ttgctaaaat acattgagga gcctcaggga
    27721 gaagcttaca tatttttatt gaccaatgat gataacaaag tgcttccgac cattaaaagt
    27781 cggacacagg tttttcagtt tcctaaaaac gaagcctatc tttaccaatt ggcacaagaa
    27841 aagggattat taaaccatca ggctaagcta gtagccaaac ttgccacaaa caccagtcat
    27901 ctagaacgtc tgttgcaaac gagcaagctt ttagaactga taactcaagc agagcgtttt
    27961 gtatctattt ggctgaaaga tcagttgcag gcatatttag cgttgaaccg tctggtacag
    28021 ttagcaactg aaaaagaaga acaagattta gttttgaccc ttttgacctt gctcttggca
    28081 agagagcgtg cgcaaacgcc tttgacacaa ttggaggctg tctatcaggc taggctcatg
    28141 tggcagagca atgttaattt tcaaaacaca ttagaatata tggtgatgtc agaataagtg
    28201 caattggaat tcgttatggg gaaacgaagc ttgtcaaaag acttgcccgt agcgaccaaa
    28261 gtagcggcgc ataagggcaa aaaagctttt gaagaaaata ctgcctttgc aacagatttg
    28321 atgaaagaag tatcacgatt aataacacaa aatcaacttg aaatgacgtt tgttaatagt
    28381 gtctttctct tagatcagca tgttgtccta attccctttt cagcagaaga gcacatggat
    28441 ttttacaact gttaaaagat ttagcggtcg attttaggtc aagaagtgag ctgccccaga
    28501 ttaacagcca agaagatttc attttctatg gaggctatgg accgtgtggc aggccactgt
    28561 gctgctttcg tttttgggaa aatttctgac agtatctatt aaaatactaa aaagtcaagg
    28621 gttatcattg actttgggta aagcaacaag cccttatggc cgtttgcttt gctgtctcta
    28681 tgatgaaggt gtcttttacc aataaagcaa gaaaaaattc cctgaatatg gtaccatagt
    28741 agagacaagt gatggccctg caacagtagc agccgttgat atatttacag atcccattaa
    28801 ggtgcggtta aaagaccagt tgaccttagt cacttatgct ttagaggagg ttaaagtagg
    28861 tgaataaaaa agaattattc gatgcttttg atggattttc ccaaaattta atggttactt
    28921 tagctgaaat tgaagccatg aaaaaacaag tccaatcact agtagaagaa aacacgattc
    28981 ttcgcctaga aaatacaaaa ctacgggaac gtttgagtca cctagaacat gaaacggtag
    29041 ctaaaaatcc ttccaaacaa aggaaggatc acttagaggg aatttatgat gaagggtttc
    29101 atatctgcaa ttttttctat ggacaacgtc gtgaaaatga tgaagaatgt atgttttgca
    29161 gagaattatt agatagaaag taagggcatg caggttcaaa aaagttttaa agacaaaaaa
    29221 acaagcggaa ccttgtattt ggttccaacc ccaattggca atctgcagga catgaccttt
    29281 agagcagtgg caacgttaaa agaggttgat tttatttgtg cagaagacac aagaaacaca
    29341 ggtcttttgc taaaacactt tgatattgct accaagcaaa tcagctttca tgagcacaac
    29401 gcctatgaga agattcctga tttaattgat ttattaatat caggacggtc actagctcag
    29461 gtgtctgatg caggaatgcc atcgatttct gatcctgggc atgatttggt caaggctgct
    29521 attgatagtg atatcgcagt cgttgcttta ccaggtgcct cagcagggat tacagctttg
    29581 attgctagtg gactggctcc tcaaccccat gttttttatg ggtttttacc cagaaaagca
    29641 gggcaacaaa aggctttctt tgaggacaaa caccattacc cagagacaca aatgttttat
    29701 gaatcaccct atcgcatcaa agataccctg accaatatgt tggcttgtta tggtgatcgt
    29761 caagtggtgc ttgtcagaga attaaccaag ctttttgagg agtaccaacg ggggtcgatt
    29821 tcagaaatct tgtcctacct tgaggaaaca cccctcaaag gggagtgtct gctgattgtg
    29881 gctggagccc aagcagacag tgaggttgag ctgacagctg atgttgactt agtgtctcta
    29941 gtgcaaaaag aaattcaagc aggagccaag ccaaatcagg ctattaaaac aattgctaaa
    30001 gcttaccagg taaatcgcca agagctttac caacaatttc atgacttata agtcatcgta
    30061 gattaggaga aaaacaaatg acagaagatc aagcaactat ccttatttta ggagtatacg
    30121 gaatcatatt ggctgtattc ttattatcag ctttattatg ccttatcgct aactggcgac
    30181 tctttaaaag agcaggttac aaaggatggt atagtctcat tcctttctat gcaggttttg
    30241 tcaaacacaa aatcactttt ggagaagata ataaatggtt ttactttatt ggttgggtca
    30301 ttgctattta ttattactat gtgcactttt gctatgtccg tgcttttggt ggatcaaagg
    30361 gtctagcagt atttggcttg tttttcccag gcattgcttc tttgatagtg gcttttggaa
    30421 aaacttatac cacacaagaa tgccaccctg tgccacatct tttaaactaa gagaaaaaag
    30481 accatcaatt ggatttattg atggtctttt aggtgtttaa atgattttag tcccgtgaac
    30541 aatggccgtt ccagtgagtt gactcaagct ttggcaattc tcagcagtga tgcctccccc
    30601 aatcatgatt tcaatgcgtt tattggcata ggtcacaaga cttttaagct gttccacatt
    30661 gtctgtaata ggagtagctt caggtgagcc atgagttagc acacgcacaa agccataatc
    30721 aatcagttgg tcaagcgctt ggtgctggtg atcagtcgga atccggtcaa aagccatgtg
    30781 gaaaaccagt ggcaagcctt gtgtagcagg cagtaattgc tcgatagcgt cggtatccag
    30841 ttgattttct gtggtcagca agcctaagac tagcgcatct gagccagctt caacagcttt
    30901 taagatatct tcttccatag cttttagttc gaggtcgtta tagacaaaat cgccaccgcg
    30961 aggtcgaatc atggtcgcta cgctaatctt tttatcgtgt aagagctgac aggcttcttt
    31021 gatgacgcca taagatggcg tggtccctcc gacagctagg ttatcacaga gttccacacg
    31081 actgatttga ccagcatcaa gggttggcag tagtgtgagg ttctcagcac aaaattcttt
    31141 aatcattttt agatctcctt tatcagtaat attatagcac gaatgaagct agtcatcagg
    31201 aaacattttt gtcaaatcat ggacattatg ctatactcac tagtattaaa agtaggccaa
    31261 aacagcagca aatactttga aaaaagattg ctatgttcta cggcaatatc agtctttacc
    31321 aacgaactct caagaagaaa agaaagacaa agcttagcat tttaaaaaag cccccttttt
    31381 tttgtgaaat gatgaccaaa aacaggcgcc tcacgcctaa aacagttaca ctaaaggaga
    31441 acaaatgatt acgatttacc aatacccaaa atgtagcacc tgccaaagag ccatggctga
    31501 attaaagcaa ctggttagtg actttgaagc cattgacatc aaagctaatc cacccaaagc
    31561 tcaggacctc aaacattgga tggaaacatc tggttatacc atcaaaaatt tctttaatac
    31621 cagtggtaac agctaccgcg aattgggact taaagataaa atagaccagc ttagccttga
    31681 taaagctgct gaacttttag ccacagatgg tatgttgatt aaacggccta ttctgattaa
    31741 ggacggtaac gtcttacaag ttggctatcg caagccatat caagagttgg atttaggata
    31801 atgcgacaaa gtctcaaaaa aggacaaggc aacattataa cgccttgtcc ttttttggga
    31861 tctgttttta gaaattagag atcaatatct agtaaaattg gcgtatggtc ttggcgttcc
    31921 ccagaagaaa tcatttcaga acgcttaacc ttatccacaa gtcggtttga agctagccaa
    31981 tagtcaattc tccaaccggt attattgatt ttgctggttt tgctacgttg tgcccaccag
    32041 gtataaacat gaggaatatc gccgtgcacg tgacgaaaag tatctgtaaa gcctcttgct
    32101 aataggttag taaagccttg acgttcttcg tcggtaaaac caggagaacg tcgattgctg
    32161 tttggatttg ccaaatcaat ctctttatgg gcaacattgt aatctcccgt agccaaaaca
    32221 ggcttttgag catccagttc agtcaaataa tcagcgtatt tgtggtccca aatttgacgg
    32281 tcatctaaac gtctaaggcc atcaccagca ttaggcgtgt aaacctgtgt gacgaaaaag
    32341 tcttcaaatt ctagggtaat gatacggccc tcagcatcca ttgttgttgg ggcaccaatt
    32401 tctggaaaag taatgacagg gtttaacgtg tttttgtaca ggaacatggt gccagcatag
    32461 cctttcctag caggctcaac tgaagaacgc cacacatgca aatagtttgg aaagtaacta
    32521 agtagggtct cgatatgttt tttggtaggc cccttagcag ataatttagt ttcttggatg
    32581 gcaataatat ccgcatcttg agcgactaaa gtgtctaaaa cagcgcgtga taaaagcgca
    32641 cgaggggact ctcctgtgag agcagcattt aaggaatcaa tgttccatga aatcagtttc
    32701 atttggtttc tctttctaac agatagtctt gttgttattg taacaaaaaa cgaaacgata
    32761 agcgactttg ggcacctagc ccccataaaa cagtctagcc aaatgaagca tagcagcgta
    32821 agaacaagac aaggaggtga tcagtgagca tatcgtttga cagttaagag taggattact
    32881 ataatagaag cataaatgta agcgctaaca aaataaaaaa tataggagaa tgtcaatggc
    32941 acaaaaaaca gtcatcaccg aagaaacaac cgattttgtt atggatttca aaacaagtag
    33001 cgctgaggga aatgttgatt ttattaacgt ttttgacctt gagaaaatgg cacaacaggt
    33061 catccctaaa ggagcctttg gttatattgc tagtggtgct ggtgatacct ttaccctcca
    33121 tgaaaatatt cgctcattta atcataaatt aattgtccct cactccctca aaggggttga
    33181 aaatccgtca acagagatta cgtttgatgg tgattactta acctctcctc ttattttagc
    33241 acctgtagcg gctcataaac tggccaatga acaaggagaa gtagcgtctg ctaaaggatt
    33301 gaaggaattt ggaagtatct acaccactag ttcctactca acaactgacc tgccagaaat
    33361 cagtgctgcc ttaggtggga caccccattg gtttcaattt tattacagta aagacgatgg
    33421 cattaatcgt aatattatgg atcgtgtcaa agcacaaggt tgcaaagcta tcgttttgac
    33481 agcagatgca acagttggag gaaaccgcga agttgatagg cgaaacggtt ttgtttttcc
    33541 ggtcggtatg ccaattgttc aagaatattt acctgatggt gcaggtaaaa caatggatta
    33601 tgtctataaa tcagctaaac aagcgcttac ctcaaaagat attgaatata tcgcaactta
    33661 ctcaggcctg cctgtttatg tcaaaggacc acagtgtgct gaggatacct tgcgggcatt
    33721 ggacgcagga gcatcaggta tctgggtaac caatcatggt ggccgtcaat tagatggtgg
    33781 tccagctgct tttgattcct tacaagaagt cgctgaagca gttgatcaaa aagttcctat
    33841 tgtctttgac tcaggtataa gacggggtca acatattttc aaagctcttg cttcaggtgc
    33901 tgaccttgtt gccttggggc gtccagcgat ttacggcttg gctatgggag gaagcattgg
    33961 tactcgtcag gtctttgaaa agttaaatga cgagttaaaa atggttatgc aactggctgg
    34021 gacacaaact atccaagatg ttaaagcctt taaccttcgc cacaatccgt atgattcatc
    34081 gattccattt gatcaaaatg cgctacgctt agattagaac agacaaaaac ctccgctatc
    34141 atgtcacaaa tagtagaggt tttacactgc aaaaagaggt atgaaaatcc aataacatag
    34201 ttacaaggtt ttcgtttacc ccccactaat agattaaaat gaaagacttc ttacattaat
    34261 agaaatttct gttgcttttc tcagaaaaat gtggttaaat aatcaaatat tattaacgaa
    34321 aaatgagtta atgattaaca ttaaactggt tttagttaaa acatttagga gggtatcagg
    34381 tggagaaaaa gcaacgtttt tcccttagaa aatacaaatc aggaacgttt tcggtcttaa
    34441 taggaagcgt tttcttggtg atgacaacaa cagtagcagc agatgagcta agcacaatga
    34501 gcgaaccaac aatcacgaat cacgctcaac aacaagcgca acatctcacc aatacagagt
    34561 tgagctcagc tgaatcaaaa tctcaagaca catcacaaat cactctcaag acaaatcgtg
    34621 aaaaagagca atcacaagat ctagtctctg agccaaccac aactgagcta gctgacacag
    34681 atgcagcatc aatggctaat acaggttctg atgcgactca aaaaagcgct tctttaccgc
    34741 cagtcaatac agatgttcac gattgggtaa aaaccaaagg agcttgggac aagggataca
    34801 aaggacaagg caaggttgtc gcagttattg acacagggat cgatccggcc catcaaagca
    34861 tgcgcatcag tgatgtatca actgctaaag taaaatcaaa agaagacatg ctagcacgcc
    34921 aaaaagccgc cggtattaat tatgggagtt ggataaatga taaagttgtt tttgcacata
    34981 attatgtgga aaatagcgat aatatcaaag aaaatcaatt cgaggatttt gatgaggact
    35041 gggaaaactt tgagtttgat gcagaggcag agccaaaagc catcaaaaaa cacaagatct
    35101 atcgtcccca atcaacccag gcaccgaaag aaactgttat caaaacagaa gaaacagatg
    35161 gttcacatga tattgactgg acacaaacag acgatgacac caaatacgag tcacacggta
    35221 tgcatgtgac aggtattgta gccggtaata gcaaagaagc cgctgctact ggagaacgct
    35281 ttttaggaat tgcaccagag gcccaagtca tgttcatgcg tgtttttgcc aacgacatca
    35341 tgggatcagc tgaatcactc tttatcaaag ctatcgaaga tgccgtggct ttaggagcag
    35401 atgtgatcaa cctgagtctt ggaaccgcta atggggcaca gcttagtggc agcaagcctc
    35461 taatggaagc aattgaaaaa gctaaaaaag ccggtgtatc agttgttgta gcagcaggaa
    35521 atgagcgcgt ctatggatct gaccatgatg atccattggc gacaaatcca gactatggtt
    35581 tggtcggttc tccctcaaca ggtcgaacac caacatcagt ggcagctata aacagtaagt
    35641 gggtgattca acgtctaatg acggtcaaag aattagaaaa ccgtgccgat ttaaaccatg
    35701 gtaaagccat ctattcagag tctgtcgact ttaaagacat aaaagatagc ctaggttatg
    35761 ataaatcgca tcaatttgct tatgtcaaag agtcaactga tgcgggttat aacgcacaag
    35821 acgttaaagg taaaattgct ttaattgaac gtgatcccaa taaaacctat gacgaaatga
    35881 ttgctttggc taagaaacat ggagctctgg gagtacttat ttttaataac aagcctggtc
    35941 aatcaaaccg ctcaatgcgt ctaacagcta atgggatggg gataccatct gctttcatat
    36001 cgcacgaatt tggtaaggcc atgtcccaat taaatggcaa tggtacagga agtttagagt
    36061 ttgacagtgt ggtctcaaaa gcaccgagtc aaaaaggcaa tgaaatgaat catttttcaa
    36121 attggggcct aacttctgat ggctatttaa aacctgacat tactgcacca ggtggcgata
    36181 tctattctac ctataacgat aaccactatg gtagccaaac aggaacaagt atggcctctc
    36241 ctcagattgc tggcgccagc cttttggtca aacaatacct agaaaagact cagccaaact
    36301 tgccaaaaga aaaaattgct gatatcgtta agaacctatt gatgagcaat gctcaaattc
    36361 atgttaatcc agagacaaaa acgaccacct caccgcgtca gcaaggggca ggattactta
    36421 atattgacgg agctgtcact agcggccttt atgtgacagg aaaagacaac tatggcagta
    36481 tatcattagg caacatcaca gatacgatga cgtttgatgt gactgttcac aacctaagca
    36541 ataaagacaa aacattacgt tatgacacag aactgctaac agatcatgta gacccacaaa
    36601 agggccgctt cactttgact tctcactcct taaaaacgta ccaaggagga gaagttacag
    36661 tcccagccaa tggaaaagtg actgtaaggg ttaccatgga tgtctcacag ttcacaaaag
    36721 agctaacaaa acagatgcca aatggttact atctagaagg ttttgtccgc tttagagata
    36781 gtcaagatga ccaactaaat agagtaaaca ttccttttgt tggttttaaa gggcaatttg
    36841 aaaacttagc agttgcagaa gagtccattt acagattaaa atctcaaggc aaaactggtt
    36901 tttactttga tgaatcaggt ccaaaagacg atatctatgt cggtaaacac tttacaggac
    36961 ttgtcactct tggttcagag accaatgtgt caaccaaaac gatttctgac aatggtctac
    37021 acacacttgg cacctttaaa aatgcagatg gcaaatttat cttagaaaaa aatgcccaag
    37081 gaaaccctgt cttagccatt tctccaaatg gtgacaacaa ccaagatttt gcagccttca
    37141 aaggtgtttt cttgagaaaa tatcaaggct taaaagcaag tgtctaccat gctagtgaca
    37201 aggaacacaa aaatccactg tgggtcagcc cagaaagctt taaaggagat aaaaacttta
    37261 atagtgacat tagatttgca aaatcaacga ccctgttagg cacagcattt tctggaaaat
    37321 cgttaacagg agctgaatta ccagatgggc attatcatta tgtggtgtct tattacccag
    37381 atgtggtcgg tgccaaacgt caagaaatga catttgacat gattttagac cgacaaaaac
    37441 cggtactatc acaagcaaca tttgatcctg aaacaaaccg attcaaacca gaacccctaa
    37501 aagaccgtgg attagctggt gttcgcaaag acagtgcctt ttatctagaa agaaaagaca
    37561 acaagcctta tacagttacg ataaacgata gctacaaata tgtctcagta gaagacaata
    37621 aaacatttgt ggagcgacaa gctgatggca gctttatctt gccgcttgat aaagcaaaat
    37681 taggggattt ctattacatg gtcgaggatt ttgcagggaa cgtggccatc gctaagttag
    37741 gagatcactt accacaaaca ttaggtaaaa caccaattaa acttaagctt acagacggta
    37801 attatcagac caaagaaacg cttaaagata atcttgaaat gacacagtct gacacaggtc
    37861 tagtcacaaa tcaagcccag ctagcagtgg tgcaccgcaa tcagccgcaa agccagctaa
    37921 caaagatgaa tcaggatttc tttatctcac caaacgaaga tgggaataaa gactttgtgg
    37981 cctttaaagg cttgaaaaat aacgtgtata atgacttaac ggttaacgta tacgctaaag
    38041 atgaccacca aaaacaaacc cctatctggt ctagtcaagc aggcgctagt gtatccgcta
    38101 ttgaaagtac agcctggtat ggcataacag cccgaggaag caaggtgatg ccaggtgatt
    38161 atcagtatgt tgtgacctat cgtgacgaac atggtaaaga acatcaaaag cagtacacca
    38221 tatctgtgaa tgacaaaaaa ccaatgatca ctcagggacg ttttgatacc attaatggcg
    38281 ttgaccactt tactcctgac aagacaaaag cccttggctc atcaggcatt gtccgcgaag
    38341 aagtctttta cttggccaag aaaaatggcc gtaaatttga tgtgacagaa ggtaaagatg
    38401 gtatcacagt tagtgacaat aaggtgtata tccctaaaaa tccagatggt tcttacacca
    38461 tttcaaaaag agatggtgtc acactgtcag attattacta ccttgtcgaa gatagagctg
    38521 gtaatgtgtc ttttgctacc ttgcgtgacc taaaagcggt cggaaaagac aaagcagtag
    38581 tcaattttgg attagactta ccggtccctg aagacaaaca aatagtgaac tttacctacc
    38641 ttgtgcggga tgcagatggt aaaccgattg aaaacctaga gtattataat aactcaggta
    38701 acagtcttat cttgccatac ggcaaataca cggtcgaatt gttgacctat gacaccaatg
    38761 cagccaaact agagtcagat aaaatcgttt cctttacctt gtcagctgat aacaacttcc
    38821 aacaagttac ctttaagata acgatgttag caacttctca aataactgcc cactttgatc
    38881 atcttttgcc agaaggcagt cgcgttagcc ttaaaacagc tcaagatcag ctaatcccgc
    38941 ttgaacagtc cttgtatgtg cctaaagctt atggcaaaac cgttcaagaa ggcacttacg
    39001 aagttgttgt cagcctgcct aaaggctacc gtatcgaagg caacacaaag gtgaataccc
    39061 taccaaatga agtgcacgaa ctatcattac gccttgtcaa agtaggagat gcctcagatt
    39121 caactggtga tcataaggtt atgtcaaaaa ataattcaca ggctttgaca gcctctgcca
    39181 caccaaccaa gtcaacgacc tcagcaacag caaaagccct accatcaacg ggtgaaaaaa
    39241 tgggtctcaa gttgcgcata gtaggtcttg tgttactcgg acttacttgc gtctttagcc
    39301 gaaaaaaatc aaccaaagat tgataacaaa gcgcaaagag acaacaaatc atccctttta
    39361 acagtctgac ctttctttga gattgagctg gcagatgatc atttcttaac aaaagttaaa
    39421 gagttgagca aagtaaggaa cagacataaa gaccataaaa gcaagccagt ttggcttgct
    39481 tttatggtgt tattgtcgtg tgctacgatg actaaaaaag aacaacgaac aatgacctcg
    39541 aatcaccaaa aggacttgat ttgatagctt ccctatgcta tactaagcct attctttcaa
    39601 gaaggactcc ttttgtggaa aagactgaaa aaaaggacac taatctatcc aaaaactcca
    39661 gatgagtagc tgcaaacgat gcctttgctg tgatcaaggt ggtaaagcag actgacttgt
    39721 cactatctga gcaggtgtca aaaaaagaag ctttggcttt gtcattcaac atactgagct
    39781 tcagtctttc agaacggaga cacccccagt tttgtactca aaaagcataa acagctctgc
    39841 tgatgtgaca tctgatttct acgtgcgcag tgagccaaaa cagctgctgt ttgctatgga
    39901 aaaagtggcg ccaatcgaga tttttgagac cctaggctca aaaataaggc atagaattcc
    39961 aaaggaagtc gctgccgtga gcacaaccta agaaaaacta tcccaaaaga ctttttctgc
    40021 aatttgaaat actgaatttc agtatttttt cttttgtaac taagagcaat gaatgaggta
    40081 aaaaaaggca acaatgtcaa aaaagaaacg aaaacactat caggtttatg agggattacg
    40141 ctgtgctatg acgctttgtt ttatcagtgg ctatgtcaat gcctttacct atatgaccca
    40201 aggaaaacgt tttgcaggtg ttcagacagg caaccttttg tcatttgcca ttcgcttgtc
    40261 agaacagcaa ctgaaggagg cactgcaatt tttacttccc atgatcgttt ttatgcttgg
    40321 gcagtccttt acttatttca tgcaccgctg ggccactaaa aaagggctcc actggtactt
    40381 attatcaagt gttatcttaa cagggattgc ttttggaacg gccctattca cgccttttct
    40441 tccttccaat gttacggtag cagctttagc cttttttgcc tctattcagg ttgatacgtt
    40501 taaaacctta cgaggagcta gctatgctaa tgtgatgatg acaggaaata tcaaaaatgc
    40561 cgcctattta ctaaccaaag gcttgtacga aaaaaatcac gaactaacac atatcggacg
    40621 caacacctta atagtcatct tggcttttgc tgttggggtg gtttgttcga cgttgctttg
    40681 catagcttat ggcgagtatg ctttgatgcc tattttaatg cctttactct atgtcaatta
    40741 cctgttggct caggaatttt atcacattca aaccaaaatc aaaccgatta aaagaactta
    40801 atggacttgt ggagaaagaa agttcattta gggtaagttt ttactcaccc tcctttgatt
    40861 gactggtttt gctgcccctt aaaatatgat ataatagacc attgatagct gttacttaac
    40921 agaaggctga taaaaaaggt tccattagcc ttgagggttg aatttaaaca ggaaaaaacg
    40981 aaatcctaca ctatgcatct caatcgtact ttcatttgag tatggttctg aaaggaaact
    41041 atgatgaaaa aaccatttta cattacgaca cccatttatt acccatctgg gaaattacac
    41101 attggttctg cctatacaac tattgcttgt gatgtcttgg cacgctacaa gcgcctgatg
    41161 ggccatgagg tcttttacct cacaggacta gatgaacacg gacaaaagat tcaaaccaag
    41221 gcaaaagaag ctggtattac acctcaaacc tacgttgata acatggcaaa ggatgtcaaa
    41281 gccctttggc aattgctaga tatttcctat gacacattta tccggacaac ggacgattac
    41341 cacgaagagg tcgttgctgc tgtctttgaa aaattgctgg cgcaagatga catttacctt
    41401 ggcgaatact ctggttggta ttctgtctct gatgaggaat ttttcactga aagccaatta
    41461 aaagaagtct ttagagatga agacggtcag gttattggag ggattgcccc atcaggtcat
    41521 gaggtcgagt gggtctctga agaatcctac ttcctacgcc ttagcaaata cgatgatcgt
    41581 cttgtggcct tctttaaaga gcgacctgac tttatccaac cagatggtcg tatgaatgaa
    41641 atggtgaaaa actttatcga gccaggccta gaagatttgg ctgttagccg tactaccttt
    41701 acatggggtg tacctgttcc atcagaccca aaacacgtgg tttatgtctg gatcgatgcc
    41761 ctcttaaact acgcgacagc tcttggttat cgtcaagcta atcacgctaa ctttgataag
    41821 ttttggaatg gaacggtttt ccacatggtt ggaaaagata tcttgcgttt tcatagcatc
    41881 tactggccaa ttttactcat gatgcttgat ttaccaatgc cagaccgctt aattgcccat
    41941 ggttggtttg tcatgaaaga cggtaaaatg tctaaatcaa aaggcaatgt ggtctatcca
    42001 gaaatgttag ttgagcgctt tggacttgat cctcttcgtt attacctcat gcgttctttg
    42061 ccagttggtt cagacgggac ctttacccct gaagattatg tgggtcgtat caactatgag
    42121 ttagccaacg accttggcaa tttattgaac cgtaccgttg ccatgatcaa caagtatttt
    42181 gacggcacgg tgccagctta tgttgacaat ggaactgcct ttgatgctga cttaagtcaa
    42241 ctgattgatg ctcagctagc agactaccat aagcacatgg aagcggtgga ctacccacgc
    42301 gccttggagg ctgtttggac catcatcgct cgtaccaaca aatacatcga tgaaaccgct
    42361 ccttgggtgc tcgctaaaga agatggtgac aaagctcaac tagccagtgt catggcacac
    42421 ttagcagcca gcttgcgtct ggtcgctcat gtgatccaac cctttatgat ggaaacatca
    42481 gctgctatca tggcccagct tggtttggaa cctgtttctg atttgtcaac acttgctcta
    42541 gcagattttc ctgccaatac aaaggttgtt gccaaaggga caccgatttt cccacgtctt
    42601 gacatggaag ctgagattga ctacatcaaa gcccaaatgg gtgacagctc agctatttcc
    42661 caagaaaaag aatgggtccc tgaagaggtt gcgctcaaat ctgaaaaaga cgtcatcaca
    42721 tttgaaacct ttgatgctgt ggaaatccgt gtggcagaag tcaaggaagt gtcaaaagtg
    42781 gaaggttcag aaaaattgct gcgctttaga gtagatgcag gagacgggca agaccgtcaa
    42841 atcttgtcag gtattgccaa attttacccc aacgaacaag aattagtggg taaaaaacta
    42901 caaattgttg ctaacctgaa accgcgtaaa atgatgaaaa aatacatcag tcaagggatg
    42961 attctatcag cagagcatgg agatcagcta acggtcttaa ccgttgattc ctctgttcca
    43021 aatggaagta tcattggctg atgctgacct attattcaaa aaacctaagc aagaacatgt
    43081 gcttaggttt ttttgattgc cttcaagaaa gacgaataac gagatgggtg atatgacatc
    43141 aaaagcataa ctatcctagg acctgtccta gtaagattgc tgtgcttttg acaagtgaac
    43201 agagaggtct taaaactata tcttgtcata aaaaagattg caaaacacta tatcttgtgt
    43261 tattatggtt tttataaaag ttaagcatac ttaactttag ccaaacaaaa gaggacacta
    43321 gagcgtgtcc cacaagacag ttgagccctt cgctttttta gtagagtagg agtgctcaag
    43381 tcaaaaagag acatcccatc aaaccattgc tgtttagcag gtctttttgt gttgctcaaa
    43441 aaaacaattc ctgtctgttt ggcgtctagt gatgacttag gcttagcgct actagacttt
    43501 tgtttgaaaa atacctcaag ccttgaagga gacaaatgac ccaacattat tatgaacgtt
    43561 cgcaatcccc aattgaatac gccctatctg aaacacaaaa acagttgcgc tccatcaatt
    43621 ggaattacct taatgatgac aaagatttag aagtgtggaa ccgtgtcact caaaattttt
    43681 ggttgcctga aaaggttcct gtttctaatg atttaaattc ttggcgctcc ttgggtgagg
    43741 attggcaaca gctcatcaca aggacctaca ctgggttgac cttactagat acagtacaag
    43801 caacggttgg tgatgtggca caaattcagc attcacaaac cgaccacgaa caagtcatct
    43861 atacgaactt tgcctttatg gtggggattc atgcccgctc ttacgggacg attttttcga
    43921 ccctttgcag cagcgagcaa atcgaagaag cacatgaatg ggtggtctca acacagagct
    43981 tgcaagaccg tgcccgtgtc ttgattcctt actatacggg tgatgaccct ttgaaatcaa
    44041 aagtagcagc agctatgatg ccaggatttt tgctgtatgg cggcttttac cttccttttt
    44101 acctatcagc acgtggtaaa atgccaaaca catctgatat catccgcctg attttacgcg
    44161 acaaagttat tcacaactat tacagcggtt acaaatacca acaaaaagta gcacgtctta
    44221 gcccagaaaa acaggctgaa atgaaggcct ttgtctttga cttgctctat gaactcatcg
    44281 accttgaaaa agcttacttg agagaactgt atgcaggctt tgatttggca gaagatgcta
    44341 tccgttttag cctttataac gctggaaaat tccttcaaaa tttaggctat gagtcgccct
    44401 tcacagatga agaaacgcgc gtttcaccag aagtatttgc tcagctatca gcgcgtgcag
    44461 acgaaaacca tgactttttc tcaggcaatg gctcatctta tgtgatgggg atcaccgaag
    44521 aaaccacaga tgacgattgg gagttttaag aaatggcaga gctgattatt gtgtattttt
    44581 catctaagtc caataacacc catcgcttcg tccaaaaatt aggcctgcct gctcagcgca
    44641 taccagtaga taataggcca cttgaagttt ccacccatta ccttttgatt gtgcctacct
    44701 atgcagctgg tggctcagat gccaaaggag ccgtttctaa acaagtgatt cgttttttga
    44761 ataatcctaa caatcgtaaa cattgtaagg gagtgatttc ttctggaaat accaattttg
    44821 gcgatacctt tgccttagca ggccctatca tttctcaaaa attgcaggtc cccttattac
    44881 accaatttga actattaggc actgctacag atgtcaaaaa ggtacaggcg atttttgccc
    44941 gcttaaagca tcacacacac gacaagcaaa aacaaaccaa caacctgatt acagaaagga
    45001 cacacccatg tcacaaacca atgcgtcata cctctcatta aatgcactga cccgttttaa
    45061 aaaaccagac ggcagctacc attttgatag cgataaagaa gctgttaggc gctacctgga
    45121 agaacatgtc tctcccaatc aaatggcttt taactcacta gaagataagc tagcttacct
    45181 catcaatgaa gggtattatg agcaggccat ttttgatgcc tatcctaatg accttatcaa
    45241 ggaggccttt cattatgcct atcaacaagg ctatcgcttt ttaaatctca tgggcgctat
    45301 gaaattttac cagtcctatg ccttaaaaac cttggacggt aagcagtatc tagaaacatt
    45361 tgaagaccgt gctgtgatga atgcactctt tttagctgat ggagatcaaa cctttgtctt
    45421 tgacgtgatt gatgccatct tgcaccgacg ctttcaacca gctaccccaa cgtttttaaa
    45481 tgccggaaaa aaacgccgtg gcgaatacat ttcgtgctat cttcttcgtg tcgaagacaa
    45541 tatggaatct atctctcgcg ccattagcac cagcttgcaa ctctcaaaaa gaggaggcgg
    45601 agtcgccttg tgcctcacca acctcagaga aatcggagca ccgataaaag ggattgaaaa
    45661 tcaggcaaca ggcatcgttc ctgtcatgaa actactagag gactcttttt cctatgccaa
    45721 tcaactaggt cagcgccaag gagcaggtgc ggtttacctt catgcccatc accctgaggt
    45781 tttgaccttt ttagacacca aacgtgaaaa tgccgatgag aaaattcgca ttaagtccct
    45841 agcattggga cttgtgatcc cagatattac cttccagtta gccaaagaaa acaaagacat
    45901 ggcactcttt tcaccctatg atatcaagcg tgcctatggc aaggacatgt cagacatctc
    45961 catcacagag gaatacgata aactgctagc caatccagcc atcaaaaaga cctacatcag
    46021 tgctagaaag ttctttcagt taattgcaga gctacatttt gagtcaggct acccttacct
    46081 cttgtttgat gacacggtca ataagcgcaa ccctcatgcc aaaaaaggca gaatcgtcat
    46141 gtctaacctg tgttctgaaa tcgctcaagt tagcacccca agcactttca aagaagattt
    46201 gagttttgaa accattggag aggatatctg ctgtaattta gggtctatca atattgccca
    46261 ggctatggca gatgcgccac actttgaaca gctcatcaca acgagcatca gagcacttga
    46321 tcgtgtctct agagtgtctg acctgaattg tgcgccttct gttgagacag gcaatgcagc
    46381 caaccatgca gtaggattag gcgccatgaa cctacatggt tttttggcaa ccaaccacat
    46441 ctactatgat acaaaagaag ccgttgactt tacagatctg tttttccatg ccatggccta
    46501 ttatgctttt aaagcctctt gccaattagc caaagaaaaa ggcgcttttg caggattttc
    46561 gttatcaacc tattcagatg gcacttattt tgccaagtat ttgcaagaag atgccaagcc
    46621 acaaacagcc aaggttgcca cattgttgca agattacggc ttcacgttgc caacggtggc
    46681 ggattggcaa gccctagtag cagatatcaa gcagtttggc ctagccaatg cgcacttgct
    46741 agcggttgct ccgacaggct ccatcagcta cttatcatcc tgcactccga gtctacaacc
    46801 agtcgttgct cctgttgagg tccgaaaaga aggtagcctg ggcaggattt acgtccctgc
    46861 ctatcagatt gaccaggcta actatgctta ctatgaacgt ggtgcctatg aggtcggccc
    46921 aaaagccatc atcgacgttg tagctgctgc ccaaaaacac gttgaccaag ccatctcatt
    46981 gaccctgttt atgaccgatc aagcgaccac acgtgacctg aaccgctcct atatccaagc
    47041 ttttaagcaa aattgtgcat cgatctatta tgtgcgagtg aggcaagacg tcctagcagg
    47101 cagcgaacag tatgacgagg atagtcttgt gacagctcct ggagctagtg atgagaccac
    47161 cacagagtgt caaagctgta tgatctaaca gctactagaa agctctcgtg tcctatcaca
    47221 tgcataggat cagtgcactc gacctttcaa gacaagcaag catcagctct tgcttgtctt
    47281 tttttggcct caaagcccgt tagtctgctg ctatgcgagg cttttttgag catcagaacg
    47341 tcaaaaaaaa ggacatggag tccttttttt ggcgatcggt gttgaggccg tcacaaactg
    47401 cccttgaaat acgcttctat gtggagcttt ttttggtcct gtgacacgta agctccaacg
    47461 acctccagct gacagcctct tggaaacaag agctcaacct ctgaaggcac agccgaataa
    47521 ggctcgacaa aggctgcctt ggcccctttt ttgacacaga tgcgcacctc caccggtcga
    47581 tgggtcatgg cgccgttttt caaggctgtc gtgctcataa aactgtgctt ggtgtagcgt
    47641 gtaccaagct tgatcttaca aaggatatga gggtcaaact gatggttacg gtagtaagac
    47701 gtgagatcag catgtgaaac accgatatca cgcaaaaacg tctcgtatac atagcggtat
    47761 actacaatgt tccacgggat gactagccgg tgagtcgcag catcgagctg ggccacctga
    47821 tcccttagct caggcgtgag ttggctgagc tcacctttgg ctttgtctag gctggtgttg
    47881 atagggcctg cctgctgaca ggtataagca gccatcgcct cttgctcagc ccttgggtag
    47941 atgagaccct tgccccatcg ctttttaatc agtgtctcag cgcccttttg atccgaaaag
    48001 gtaaaataag caggcgtccc ctcacaaacc gcccgctcat agtgctcaca gacaaaaagc
    48061 tcgaccaagc cctcagtttg ccagatcaga ctaaaacagc taagaagaag gacaatagcc
    48121 agttgatagc gcttttttag catagttccc cctgacacca gcccaaaagg ctgacccttc
    48181 ccctagacct tttggctagc tcttgacacc accagtttct cagacaggct aatctttttg
    48241 tcatctcttt ctccctaaac agactctctt atcatgatat tatgctatta tgagcgattt
    48301 gtcaatccat agcaaccgtt ttttagttag ataagtaagc ttttgaccta gaggcagaca
    48361 agagtggcag tacctcccgt ttgctgtggt ggctaataag gactaacaca aaatctcaaa
    48421 cgctttcaaa aacagctcct aagcttaaaa aagctgatga acagatttgt tgaacttaag
    48481 agagattgcc atgattttct aatcatttga tgtttaaaat gataaaaaca tgaacttgaa
    48541 atgaaataat gagaggagta aactagaacc atatcaaaaa ataatgaaat ggagtggttt
    48601 tatgaaaaca aaatcaaaac gctttttaaa cctagcaacc ctttgcttgg ccctactagg
    48661 aacaactttg ctaatggcac atcccgtaca ggcggaggtg atatcaaaaa gagactatat
    48721 gactcgcttc gggttaggcg atttagaaga tgattcagct aactatcctt caaatttaga
    48781 agctagatat aaaggatatt tagagggata tgaaaaaggc ttaaaaggag atgatatacc
    48841 cgaacggccc aagattcagg ttcctgagga tgttcagcca tctgaccatg gcgactatag
    48901 agatggttat gaggaaggat ttggagaagg acaacataaa cgtgatccat tagaaacaga
    48961 agcagaagat gattctcaag gaggacgtca agaaggacgt caaggacatc aagaaggagc
    49021 agattctagt gatttgaacg ttgaagaaag cgacggtttg tctgttattg atgaagtagt
    49081 tggagtaatt tatcaagcat ttagtactat ttggacatac ttaagcggtt tgttctaaaa
    49141 aatatttttt atagtacaat tttttagcaa attgttttga aaaagaacac tttataaata
    49201 gttcatattt atggtataat acctaattca agtattttta aatggttggt gaattcttgg
    49261 ctgataaaat tctttattag tgttgagcag tcccactgtt ttaaaacaat tttctgctat
    49321 aattgggata atccctttag tagtcaggcc acctctgata ggggtggctt ttttgggttt
    49381 tagtgacccg tgtgttgaga aaggagcatt tatgccagaa aagaaagtgt tgcccgtcct
    49441 aagcatagtg gtgagttttg tctgcctgct tgatcatatc ttcttttttg ctacttatag
    49501 ttatctctac ttaccgcttg tagcaagtag tctagctctt atcggtctgg tgcaaaacaa
    49561 aggcaggcaa aaggtgtggt cgctagctgg actcgtccta gctgctctag ccgtggcagt
    49621 agtggcctat gcctactatg acccaaccgt catcccctac taaccttaac cactccttcg
    49681 cacgcaatca acagcacaaa aagcacccct gacaggtgct ttttgtgctt tagccaacct
    49741 atagcctcgt aatccctcac tgaaacagtc ccttaaagtt ccaccactga tcttggatgc
    49801 tctcacttaa ccgctgatgc caaggtttat ggtcttcttc tcttatctgc tttagcatgc
    49861 tttcttctag ctgtttttgt tgcttttcct cttccttttt ttgaagtgct tcttcagctt
    49921 ctttttcttt ttttatagta tcagagtctc tatagatata gctaccgaca taaaatccgt
    49981 cttctccttt aaatgagaaa gttaattttt ctcctttctt caaaggatct tctcctaagt
    50041 taagaatata aggtactcct gtataatatt gacgataagg atctgttttt gttatatttt
    50101 tttcgagaat aggactagct aaaattcctc gttctttact gttatgatca cattgtctgt
    50161 aaagatatac ccaccatcct tgagggatat atatttttac tactttacta ccaacatata
    50221 agtcttctag agtgattgtg ttgccactat aatctttaat tttttgttga ggtccatcca
    50281 aatcaaattt tactggcttt tgtgtactac tttgttcatc ctccgctctg acgctactag
    50341 ttaccccgat ggcaaagagt gccagtagca aagttaatgt ctttttcatt tcgttctctc
    50401 cttttgctca ttttttaaga caaggcttat tataccaatt cttgcgctaa aaagataggg
    50461 attgattggc tgaggcgatc ggagaagtcc tagatttctc tgagtggctg ccactcactt
    50521 aatgtttcac tattttattg ggatatgcta atacttcaag atatctttat atcgtctata
    50581 gtcaagagcc tatttgacac tttatctcta tgtaaataat ttgcacactc tgttaagtgc
    50641 tctttttggt cgcttatcct cttttaaagt tgttttatgt cagttgaaaa cgatgtttct
    50701 tgagtaacct aacttacctg atatctcgta tcgtgatacg ttatttatca atattatgaa
    50761 atagaacaac gatattaggc attcttttcg attaacttcg aatagcttaa taaatgttta
    50821 tcatctgcaa tttttagcat aatttaaaga aatacgactg tatcttgata ggta
//
LOCUS       DAUGQX010000010        43305 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUGQX010000010 DAUGQX010000000
VERSION     DAUGQX010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43305
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.010"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(115..1251)
                     /gene="dnaJ"
                     /locus_tag="VIA51_000490"
     CDS             complement(115..1251)
                     /gene="dnaJ"
                     /locus_tag="VIA51_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEQ8682456.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(1532..3358)
                     /gene="dnaK"
                     /locus_tag="VIA51_000491"
     CDS             complement(1532..3358)
                     /gene="dnaK"
                     /locus_tag="VIA51_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEQ8682457.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(3539..4111)
                     /gene="grpE"
                     /locus_tag="VIA51_000492"
     CDS             complement(3539..4111)
                     /gene="grpE"
                     /locus_tag="VIA51_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEQ8682458.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(4114..5148)
                     /gene="hrcA"
                     /locus_tag="VIA51_000493"
     CDS             complement(4114..5148)
                     /gene="hrcA"
                     /locus_tag="VIA51_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEQ8682459.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(5283..5852)
                     /locus_tag="VIA51_000494"
     CDS             complement(5283..5852)
                     /locus_tag="VIA51_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8682460.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQVA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(5849..6592)
                     /locus_tag="VIA51_000495"
     CDS             complement(5849..6592)
                     /locus_tag="VIA51_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEQ8682461.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            complement(6582..7289)
                     /locus_tag="VIA51_000496"
     CDS             complement(6582..7289)
                     /locus_tag="VIA51_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8682462.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            complement(7680..7919)
                     /locus_tag="VIA51_000497"
     CDS             complement(7680..7919)
                     /locus_tag="VIA51_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8682463.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(8138..8353)
                     /locus_tag="VIA51_000498"
     CDS             complement(8138..8353)
                     /locus_tag="VIA51_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682464.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTAYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNYHVCLHYY"
     gene            complement(8350..9789)
                     /gene="gatB"
                     /locus_tag="VIA51_000499"
     CDS             complement(8350..9789)
                     /gene="gatB"
                     /locus_tag="VIA51_000499"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEQ8682465.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            complement(9789..11255)
                     /gene="gatA"
                     /locus_tag="VIA51_000500"
     CDS             complement(9789..11255)
                     /gene="gatA"
                     /locus_tag="VIA51_000500"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEQ8682466.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQATLEDIKSREEAVGSFI
                     TVSEEVALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKEILTTAASKMLYNYEPIFN
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLASVKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(11255..11557)
                     /gene="gatC"
                     /locus_tag="VIA51_000501"
     CDS             complement(11255..11557)
                     /gene="gatC"
                     /locus_tag="VIA51_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEQ8682467.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(11789..12037)
                     /locus_tag="VIA51_000502"
     CDS             complement(11789..12037)
                     /locus_tag="VIA51_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8682468.1"
                     /translation="MIRSRSRPLIRKGLAVSLARSVKPELKLGICGEHGGDPASIAFC
                     HSQGLTYVSCSPFRVPLTRLAAAQAAIKASGHSLTQDK"
     gene            complement(12552..13106)
                     /locus_tag="VIA51_000503"
     CDS             complement(12552..13106)
                     /locus_tag="VIA51_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEQ8682469.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(13253..14035)
                     /gene="codY"
                     /locus_tag="VIA51_000504"
     CDS             complement(13253..14035)
                     /gene="codY"
                     /locus_tag="VIA51_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEQ8682470.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(14253..15467)
                     /locus_tag="VIA51_000505"
     CDS             complement(14253..15467)
                     /locus_tag="VIA51_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8682471.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            15698..16150
                     /locus_tag="VIA51_000506"
     CDS             15698..16150
                     /locus_tag="VIA51_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEQ8682472.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDNFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(16273..17661)
                     /locus_tag="VIA51_000507"
     CDS             complement(16273..17661)
                     /locus_tag="VIA51_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8682473.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDIEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            17733..18698
                     /locus_tag="VIA51_000508"
     CDS             17733..18698
                     /locus_tag="VIA51_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEQ8682474.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVILVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(19047..19751)
                     /locus_tag="VIA51_000509"
     CDS             complement(19047..19751)
                     /locus_tag="VIA51_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682475.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(19764..20666)
                     /locus_tag="VIA51_000510"
     CDS             complement(19764..20666)
                     /locus_tag="VIA51_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8682476.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDCSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            complement(20959..22974)
                     /gene="recG"
                     /locus_tag="VIA51_000511"
     CDS             complement(20959..22974)
                     /gene="recG"
                     /locus_tag="VIA51_000511"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEQ8682477.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENKSETNGLPILYSKRAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSIIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     YKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAQNIRKKEVYD"
     gene            complement(23349..24803)
                     /locus_tag="VIA51_000512"
     CDS             complement(23349..24803)
                     /locus_tag="VIA51_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682478.1"
                     /translation="MERLGGADLDYCYHNHHDTAMISAEQLVFTYHDQKNPACQISTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQNLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAVGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(24740..25420)
                     /locus_tag="VIA51_000513"
     CDS             complement(24740..25420)
                     /locus_tag="VIA51_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8682479.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWRFPEVWLLTLAVMCRFIPMIRQECCVIHRSLKIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(25417..26010)
                     /locus_tag="VIA51_000514"
     CDS             complement(25417..26010)
                     /locus_tag="VIA51_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEQ8682480.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSVFAHYLLKKHFIKSGLLS"
     gene            complement(26007..27677)
                     /locus_tag="VIA51_000515"
     CDS             complement(26007..27677)
                     /locus_tag="VIA51_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682481.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLTVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLIFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACVDHLFCVKNGSLKEVNKK"
     gene            complement(27670..29433)
                     /locus_tag="VIA51_000516"
     CDS             complement(27670..29433)
                     /locus_tag="VIA51_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEQ8682482.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(29430..30266)
                     /locus_tag="VIA51_000517"
     CDS             complement(29430..30266)
                     /locus_tag="VIA51_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682483.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNGIRTQRRDRNK
                     NR"
     gene            complement(30263..31285)
                     /locus_tag="VIA51_000518"
     CDS             complement(30263..31285)
                     /locus_tag="VIA51_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8682484.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(31287..32171)
                     /gene="isdE"
                     /locus_tag="VIA51_000519"
     CDS             complement(31287..32171)
                     /gene="isdE"
                     /locus_tag="VIA51_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEQ8682485.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHP"
     gene            complement(32155..33030)
                     /locus_tag="VIA51_000520"
     CDS             complement(32155..33030)
                     /locus_tag="VIA51_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEQ8682486.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTNLVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDSQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            complement(33227..37054)
                     /gene="shr"
                     /locus_tag="VIA51_000521"
     CDS             complement(33227..37054)
                     /gene="shr"
                     /locus_tag="VIA51_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ8682487.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKIIVDNDVYEKSLEGERTFDINYQGIKINADLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKTVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     VEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(37543..39054)
                     /locus_tag="VIA51_000522"
     CDS             complement(37543..39054)
                     /locus_tag="VIA51_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8682488.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAIGSSDNKA
                     EAENQVDDKSTDHSKSTDHSKPTDQPKPSPSKVDTAPASSLSKQLPEARTPIQSLSPY
                     VSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYD
                     STRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQ
                     ASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSG
                     KRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSY
                     AWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKVGYALSKTPKVGYAISFAPGQAGAD
                     GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN"
     gene            complement(39141..40241)
                     /locus_tag="VIA51_000523"
     CDS             complement(39141..40241)
                     /locus_tag="VIA51_000523"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEQ8682489.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(40238..40594)
                     /locus_tag="VIA51_000524"
     CDS             complement(40238..40594)
                     /locus_tag="VIA51_000524"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEQ8682490.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLNYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(40710..43229)
                     /gene="secA"
                     /locus_tag="VIA51_000525"
     CDS             complement(40710..43229)
                     /gene="secA"
                     /locus_tag="VIA51_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEQ8682491.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
BASE COUNT        13300 a         9044 c         7407 g        13554 t
ORIGIN      
        1 tttgacaaga gaaaaaaacg atatctataa aagaaaacgt tttctctaac tgttttgacg
       61 taaaaaaacg tataacttcg ggaaaattat cctgaaatta tacgtttgac atctttaaat
      121 atcctctaag gcatctttca ctttatcaaa aaaacctttt ttctttggat gtaacatttt
      181 ttcaccactc gcttctgcaa atgcttgcaa ggcttccctt tgagcgtcat tgagtttggt
      241 tggggtcaca atattaacgg taacatgttg atccccttga cctccaccac ggagttttgg
      301 tgctcctttg cctttgaggc ggaaggtttt acctgtttgt gtcccagcag ggatagccat
      361 ctcaacatcg ccatgaaccg ttggaatttc aacagtatct cctaaggctg cttgagtaaa
      421 agaaatatct aagttgtagt aaatagtgga accattgcgt tcaaattgct tacttggtaa
      481 gacattcaaa ataacaaata aatcaccata aggtccgcca ttaaagccag cttctccttg
      541 accttgtaaa cggatttgct gaccagtctc tacaccagct ggaatcttaa cagacacttt
      601 atgagcttgc ttttcatgac cagtaccgtg acaggtttga cagggttctt taatttcctt
      661 accactacca tgacaaatat cgcaggtgac ttgtcgacgc atcataccaa gtggtgtttg
      721 ggtgtcaatt gtcattacac ctgaaccatg gcacttacga caagttactg gagcggtacc
      781 aggttttgca cctgagccta aacaagtgcc gcaggttgct tcgcgattat agctaacttc
      841 tttttcaaca ccaaatacag cctcttcaaa agataaatta acacgatatt gcaaatcgtc
      901 accttgacga ggggcatttg ggtttcggct tccaccgcca ccaaagaagc ttgagaagat
      961 atcttcaaaa ccaccaaagc cacctccgtc aaaaccacca aagccgcctg ctccgccacc
     1021 aaagccgcct tgagcacctg cagcgccgta ttgatcataa gcagcacgct tttgtgaatc
     1081 acttaaggtt tcgtaagctt cttgaacatc cttatacttt tgctccgctc cagcttcttt
     1141 attgatatct ggatgatatt ttttagacat ttttcgataa gcttttttga tatcgtcctg
     1201 agaagcgtcc ttagaaaccc ccagacgatc gtaatattct gtattgttca taatgtaaga
     1261 taccaagctg taaaacgact taatgaaaaa taggaaatcc gacaaagata ctctcgtatc
     1321 taggaggtat ttctcttttt tcgcagagtc gtaggcgtgt tcaaatccgc aaaagagtct
     1381 ttacacgctt tagcctgtgt tcgaataatc gaacttgtat tcctttctta aaatattttg
     1441 acgtcagcat ttttacattt tatttagcca aaaacagagg tttggtacaa cctctgaatt
     1501 cggatattaa tgttactaga taactaaatc attacttttc tgtaaattcg ccatctacaa
     1561 catcatcatt atttgctgaa tcattagctt gtgcaccttc tgcaccttgt gctgcttgtt
     1621 gagctgctgc agcttgctcg tacattttaa cagccaaagc ttgcgctttt tcatttaatg
     1681 cttcaagttt agctttcatg tcgtcaaggt tgccagattc ttgcgcagct tttaactcgt
     1741 caagagctga ttgcgctgca tcgcgttctg tatcaaagcc tttaccttca gtttctttga
     1801 ttgttttttc agtagcaaag atagcttggt caacttcgtt tttaaggtca acttcttctt
     1861 tacgtttcgc atcggcttcg gcattagctt cagcgtcttt catcatgcga tcaatttctt
     1921 cttcagaaag tccgtcgttt gatttgataa cgatgtgttg ttccttttgc gtaccaaggt
     1981 ctttagcttt tacagaaaca ataccgtttt tatcgatatc aaatgttact tcaatttgtg
     2041 ggattccacg aggtgcagct gggatatcag tcaattggaa gcgaccaaga gtcttgttat
     2101 ctgctgccat tgggcgttca ccttgaagaa catggatatc aacagctggt tggttgtctg
     2161 ctgctgttga gaagacttgt gatttagatg ttgggatagt tgtattgcgg tcgatcaatt
     2221 tagtgaagac accacccatt gtttcaatac caagtgacaa tggtgttacg tcaagaagga
     2281 caacgtcttt cacatcccca gtgataacac caccttggat agcagcaccc atagcaacca
     2341 cttcatcagg gtttacagat ttatttggtt ctttaccagt ttcagctttt acagcttcga
     2401 caactgctgg gatacgagtt gatccaccaa caaggataac ttcatcaatt tctgacaatg
     2461 acaatcctgc atctgaaagg gcttgacgaa ctggagtttt cgtacgttct acaaggtcgc
     2521 gagtgagatc gtcaaattta gcacgagata agctcatctc caagtgaaga ggaccggcag
     2581 aaccagcagt gatgaacggt aatgaaattt gtgtttgtgt cacacctgaa agatcttttt
     2641 tagctttttc agcagcatct ttcaagcgtt gaagtgccat cttatcttgt gataagtcaa
     2701 tgccattttc tttcttaaat tcagccacta agaaatcaat aattttttgg tcaaagtcgt
     2761 caccaccaag tttgttatca cctgctgttg caagaacgtc gaagacacca tcacctaatt
     2821 caaggattga tacgtcaaat gtaccaccac caaggtcaaa aactaagatt ttttcatcct
     2881 tgtcagtctt atccatacca taagcaagtg cggctgctgt tggttcgtta acgatacgtt
     2941 ctacttcaag acctgcaatt ttaccagcgt ctttagttgc ctgacgttgt gcatcgttga
     3001 agtaagctgg aacagtaata actgcttttt ctactttttc tccaagatag tcttcagcat
     3061 aacctttaag gtattgaaga atcattgctg aaatttcttg aggagtatat tctttaccat
     3121 ttgcagaaac tttttcagaa gttcccattt tagatttaat agagattact gtttctgggt
     3181 ttgtcactgc ttgacgtttt gcagcatcac ccacgataat ttcaccattt ttgaatgata
     3241 ctactgaagg agttgtacga ttgccttctg ggttagcaat gatttttgat tcagtccctt
     3301 caagaactgc tactgctgag tttgttgtac ctaagtcaat accaataatt ttagacatgt
     3361 taatacctct tattttataa tactttatta ctttttattt caatttatct tagtaagcac
     3421 tcgaattatt ttacttccaa ttctaagcaa tcactatagt ttaatcagca agcgaaatag
     3481 cttctaactt gctatctagt ttactgtcat tacggacaaa aacgaaaact catttacctt
     3541 agttataaac aactaccatc gctggtctta gcagacgctc gtgcaattta tatccctttt
     3601 gaaagacttc tgcaatgcta tcggctggat gttcatcatc ggctgggagg gtctgaactg
     3661 ccatatgaaa gttgtggtca aacgagtcga cttctacttc ttctacgcct tcttccttta
     3721 gtgcttgaat aaggctatca cgagtcattt ctaaaccttt tttaacatca tctgtcaacc
     3781 cttcaacagc caaggcacgt tctagattgt caagcgatgg taagattgct tttgccagat
     3841 cctgagaacg atagcgttga agttgttgac gttcttcact agagcgacgc tgtatattct
     3901 gcatttctgc atgagctcgc aagtatttat tttcaaactc atcagcacgt tcgtttgcaa
     3961 gttctaactc tgatttttca ggagtttctt caataacttc ctcaactgtc tcttcagttt
     4021 cagtggcttc cacttcttct tgtaaatcgt cttttttaat ttcttctgac actgagtgcc
     4081 tccttttaaa taacttattg aatactgcca ttatcagtga acttcataat ggttagaatt
     4141 taggtatcga taataatcac ctaatttagc agccaatacc tttccaataa tgtttaccaa
     4201 actaacagac ctacgataat ccatatcaat aggaccaatc aaactcagga gtccaaaccc
     4261 acggtaagga atcaaaaatt tgtgagttaa aactgacaca tctgcaagtg cggcttcttg
     4321 actatctgcc acttggacag aagccatctc accttctttc agactttgcc tcaaagaaat
     4381 tgctacttgc tgttcattat ccaaaaactg atacgttgat agatctgaat acgttaaaga
     4441 atttaccttg ccagcaacaa ataccgtttc caaaaacagc tctgaaaaaa cataatcaaa
     4501 tagttgtaaa acattatccg tagtcacaaa atacttttga acgatctgag gaatttctgt
     4561 cctcaactta taatgaatat ctatgacact attatccagc aagcgctcct ctacgatagc
     4621 tttaaatgct atcaagtcac gtgtcaaaaa gtttcttgga atagcaaact gcactgtcac
     4681 tggcttagat tcatctaaag tcatgactgc tagagcatca tggttgctaa gctgaacaac
     4741 atcaaaccct gttaaacgtt gacgagctgg ctccacatct aaaataacgg atgtatagcc
     4801 cgtcatctcc gctaaaatgt gactagcttt ttgaagcatg tcttctaatt tgaatgcttc
     4861 aaaatcaaaa gcttttatga catgataaat atcttgctca tcaatactat ctagcctgag
     4921 ggagtgctct acaaaatact taaaaccagc tggacttggc atccgtccac tagaagtgtg
     4981 cgctttttcc aacaatccca acttctctag ttttgccata tcattacgaa tagtggcgct
     5041 actagaatca atcgttctct gtaaagcttt agaccctact ggttcatgag tttgtgtaaa
     5101 tagctcaacg attaaattca aaatatcatt ttgacgttgt gtaatcacaa accaaccact
     5161 ccctttcgtt tagcactcta tttagtagac tgctaattta taattctatt atactcttta
     5221 tgggagacat gtcaagaaaa aaactcaaaa aaattagcac tcttttataa agagcgctaa
     5281 tttcagtcat agtttgttaa atcgttactt tcaatgacct gaattagtcg cctagcatag
     5341 gttttatcag tataatgcaa atacttttgt aaacttttag ctggtgcttt ataccctttt
     5401 tctgtagcaa gattacgata caaacgctta tcgacttctt ttccctgccg aagcattcgt
     5461 aaataatctc taattgcact agcgtcatct ttataaatag catatctcac gttttggttg
     5521 gtttgtttag gggactttag ggtaatggcc acttgtcctg gagttgcttt cttgctaaaa
     5581 agattatgat acttagacgc tagtaatgtt tttccatcat gggtttccaa aagaatttga
     5641 gcaatcaaaa tagatggtct aatgccataa tattttgcca atggtttaac ttctttaccc
     5701 atttttgtaa taaattgttt ttggctgtag ttcaccctta cttctttatc tgcactagct
     5761 atcctttggc tactcagtaa gggacaaaca atcagcaata aaaagcaagc tagaagcgtt
     5821 aaaaaatacg gaaactttag tcgttttctc atcgtttctc ctttaaagca gcaatgtact
     5881 cttccaacgt taggttgtgc tgagccatat aacgagcaga cgccttgcct acatagcggt
     5941 aatgccaatc ctcataatca acccctgtac tagtcttttt tccttctgga aagcgcaaga
     6001 caaacccata atcaggtgca attttttgaa ctgctttagc tactgatgga tcactggcat
     6061 ttaaagtatc tacagtgctc atgtcaatag caagaccagt gtgatgttca ctagcccctg
     6121 gcggctgtga ataggtttgc accaaagcct ccgcagcttc ttgtgtcaat gttggatcgt
     6181 tagccatctc ttttttaata taagattggt aaagctctgt ttggtagtct acggaacggt
     6241 acccagagat aagatgttct tgcaagtcga tagcttgtgc tgctgctaaa aagtcactag
     6301 tggcttgctc aatgcgttta tccacagaaa taccattaat gtcagctaat tcaggactca
     6361 tttcttttgt aatgtgatcg cggtttacta aaaccaactc ccaatcttca acagatacct
     6421 taggtaaagc tcgtaaacgg tccgtttttt tgatatcttt ttgttggatt tcttttttat
     6481 tcaactgagt tggtgttact gactcttctg gttttataaa gaggtaaagc cctcctaaaa
     6541 aaacaataac aattagcaat tgcactaaat agtttaacga attatatttc atctgaccgt
     6601 tcttctatta tttcacgacc gcggtagcgg taactcatat ctccaatagt ctttatcgta
     6661 aattggccat catcaaattc aacaactgta acgctcccat tatcaatata ctgtttgtct
     6721 cgatctggat caatcaacca cagaaacgtt ccaattgtca taccatggct aaccacaaga
     6781 gcatttccgc cgccagcatt ttgaatagac aaggcaatag cttcaaaccc ctcccaaatg
     6841 cgcttacgaa gaacttccca tggttctgcc caattagcgg tatctacttc cacgatgctt
     6901 tctgccagtt cagaataggg aacatcacgt aggttatcac gattttcaaa ggcttttgtt
     6961 cttggaagga cacctagaaa taattctgaa tcataagtcc cttctagact cccaaaacac
     7021 cactcacgaa tacgattatc tttagtataa ggcaaaaatt cgttttctga ttctcttaaa
     7081 ataatttcta ttgtctgcat ggttcgacct gaatcacttg aaaacgcagc cttaaatggt
     7141 atagttgcat cttttaaacc taggccaagt tctcgaatac cttcttctcc tttttttgta
     7201 agaggtgtgt cactccaacc ctgagcgcga ccaatggtat taaacatcgt ttttccatgt
     7261 ctggcaatat acaaccttgt ttttgtcatt tcaacctcct aaactgtctt attaattatt
     7321 atagcattta aagaaaacac ttgcaaaaca cttcctgatg gctatttgag atcaaataga
     7381 ccactgactt attgtctatt ttattaaaaa caatgctatt gctacaattc aaatcatcac
     7441 ataaatttcc aaacgattac atttgtgtat ttcgctcaaa tatatataac aacagaccca
     7501 cactacaact aaactgacgt tacaaaatga tgtcaaaaca gtaacaaaat ctaactattt
     7561 gtcaagaaaa cgatattaaa ttttcacaca actatcttat aatgaggatg caaccaataa
     7621 aaagataaga cattttatgt tgcaaaaagg ctgcttggaa acttccatgc agcctttttt
     7681 taataccttt ttccaaaaat agctgaaaca agtacaatta caattgctgc tcccaaaatg
     7741 gacgggaaaa tagccatacc tgccaactga attccccaat ccccaaaaag cctttgccca
     7801 acagctgacc ctatgagacc tgcgataata ttagtaaaac aacccatgga ctggcttttt
     7861 tcagtcattt tacctgctat catgccgata aaggcaccta caattaaaga ccatatcatc
     7921 gttaacacct cctttcttgt aaaatccttt tagaagaact gctatccatt aaatgttctt
     7981 aactttagtt gattccttta ccttcttctt tagtaagtgt ttccgtgcct gagtaaaata
     8041 gaaaaaacaa ttccttctat taagatagat agaccgagaa cgactagaag tcttcacaca
     8101 ctaaataact taacaaactt tatcacacag ctaatcgcta ataatagtgt agacaaacgt
     8161 gatagttcat taaatacccg tcagaaactc ctgaaggttc taaagcaata cctgtcagtc
     8221 ttattttagc atagatgatg gtctttttat aggcggtcac taacatgaca tacaaaaagg
     8281 cagcctgtga aagaccgacc gccttttttt cagagacaaa atactttaac ttattgctat
     8341 cagcaactat caatctcgca atttttgcaa ttcttgtgcc aataattgtt gagcgacttg
     8401 tggattagct tgacctttgg ttgccttcat caagaagcct gtgaaagcct tatcagcatt
     8461 acgtttgcct gatttgaaat cagctactgc agcttcatta tcagcaaaga cttggtgaat
     8521 aattggtacc aaaacagcgg gatcagaaat ctgaacaagt cctgcctttt cgacgtaggc
     8581 acgtgctgag ccaccgtttt tagccaaatg cacaaagacc ttcttagcca ttttagaaga
     8641 gattgtacca tcagcaatga tagcaatcat ctccaccaaa ttttctggtg tcagagcgat
     8701 ttcttcaatg gttttgcctt ctgcatttaa gaattgggca acttctcctt gcaaccagtt
     8761 agagacttgc ttggcatcgc caccaagact tactgcagtt tcaaagaaat ctgacaagac
     8821 tttggtagct gttagctggc tagcatcata agctgagagg ccaagttcct cttcgtattt
     8881 agcacgacgc tgagctggga attgaggtaa ttgagcacgc atctcgtcaa tccaagcatc
     8941 atcaatctca tataatggca ggtctggttc tgggaaataa cgatagtccg ctgccccttc
     9001 tttgacccgc atcaaaatag tccccttatt cgcttcgtca tagcggcgcg tttcttggcg
     9061 tatcacacca cctgaacgca agagtttggc ttgacgttcc acctcaaatt caagcccttt
     9121 acggacattt gagaaggagt tcaagttttt caattcggtc tttgttccaa attgttcttg
     9181 cccgtaagga cgaagagaaa tattggcatc cacacgcatg gagccttctt ccatcttgac
     9241 atcagaaata cccgtatact ggatgatttc tttcagagct gtcaaataag cataggcttc
     9301 ttcaggagaa cgcatgtcgg cttctgacac aatctcaatc aaaggaactc cttggcggtt
     9361 aaggtccaca taagaataac catctgtgcc atgagtgttt ttaccagcat cttcttccaa
     9421 gtgtgcgcgt tcaatacgaa ttttcttggt tgaaccgtct tctagtttga tatcaatcca
     9481 gccgttgtag ccaatcggct catcaaactg tgaaatttga taagctttag gattatctgg
     9541 gtagaaataa tttttgcggt caaagtgcat ctctttatgg atgtccatat taagggcaag
     9601 cgctgctttt atgcccgcat caatcacccc tttgttcatg actggtaaga cccctgggaa
     9661 agaccaatca atcacattcg tgttggcatt tgggtcctca ccaaagtgag ctgacgaagg
     9721 tgagaaaatt ttggaattgg tatttaattc cacatggact tcaagcccaa taatggtttc
     9781 aaaattcatt acttgtcacc tccaaaaata atcggttgtt gcttgtgata atctgtcacc
     9841 gcttcaaagg ctgctgctgc ttgatagatg gtttcttcag cgtatttcgg accaattaat
     9901 tgaagcccta ctggcaagcc atcgacgaat cctgctggaa tagaaatacc tggcagacca
     9961 gccaagttaa ccggaatggt caataagtcg gccaaataca tggcaacagg atcgtggttg
    10021 agtgtgtcta agccaaaagc aaccgtcggt gttgttgggc ctagaataag atcataatcc
    10081 gcaaaaacct tgtcaaaatc ttgaataatc aaagtgcgca cttgaccggc ctttttgaaa
    10141 taagcgtcat aataacccga tgacaaacta aaggttccaa gcatgatacg acgtttcacc
    10201 tcatcaccaa agccttggct acgagtgtta acatagattt catccaagtt tttagcatcg
    10261 tcagcacgga aaccatagcg aatgccatca aaacgttgta agtttgaaga cgcttctgac
    10321 gaagcgataa tataataaac agccacaccg tacttgctat gtggaaggct gacttcctca
    10381 acagtagctc ctaaggcttc aaattgttta actgacgcaa gaaccgtttc cttaatctca
    10441 ggatcaatcc cttcgccaag atactcttta ggaagggcaa tcttcatgcc tttaatgtca
    10501 cgaccaatct tagatgtgta gtctgcaatg cggacaggcg ctgaagtggc atccttgaca
    10561 tcgctacttg caatcacatt taataattgg gcgttttctt taactgtcgg agcaaaaggt
    10621 ccaatctgat caagtgaact tccaaaagca atgagaccat agcgagaaac agtgccatag
    10681 gttggtttca aaccgacaac accattaaat gcagctggct gccgaataga accaccagtg
    10741 tctgaaccaa gagataaacg gacttgtcct gaagcgactg ctgttgccga accacctgat
    10801 gagcctccag gtacttttgt gtggtcccaa gcatttttcg ttttcttgaa ataagaggtt
    10861 tctgttgaac cacccatggc aaattcgtcc atgttggttt ttccaataac aatcatgtct
    10921 ttagcgtagg catttgctac tgatgtggca ttaaaaatcg gctcgtagtt atacaacatt
    10981 tttgaagcgg ctgtggttag gatttccttg gttgaaatat tatccttaac agctaacgga
    11041 atacctgaca tgaggttatc agcatcaata cctttggcat caattgccgc agcttgttta
    11101 agagcaactt cttctgaaac agtgataaac gatccgacag cctcctcacg agacttgatg
    11161 tcttcaagtg ttgcttgggt caattctgtt gctgaaatct ccttagctac aaggaggtca
    11221 tgcaactctt caatggtttt atgattaaaa gacattaggc atctcctccg tcatccaaaa
    11281 tagcaggtac cttgataaag tgattttctt tttcaggaac atttttaaag agcaaggcac
    11341 ggtctgttcc ttcttcagcg acatcttgac gcatcacatt tttcttatct gccatggttg
    11401 ttgtaatggc gacaccttcg gtatcaactt cgttcagcaa ttcaaccata tcaacgattt
    11461 tggataaggt cgttgcaaag gttgttgtct cactttctga aaatgataat tttgatagct
    11521 tcgcgacatg gcgaacttct tcttcagaaa ttttcatgat ttctcccatc caagatgatc
    11581 agaagtattc caattccaaa gaacagccct gctattctcc aaaggtagcg gaaaaactcc
    11641 tcacatcatt tttacatagt ctcaattatt atatcacaat tgctcccatt taccataggt
    11701 gactaatgca attctagaaa gccatacagc aaaaaacttc ctgactaagg tcagaaaacc
    11761 ttagtcagga agtgtgacaa actaaactct atttgtcttg ggtaagactg tggcctgaag
    11821 ctttgatggc agcctgagca gccgccaagc gagtaagcgg cactctaaat ggcgaacaag
    11881 aaacgtaggt caggccttgg ctgtggcaaa aggcaatgga agcaggatcg ccaccatgtt
    11941 ccccacaaat accaagtttc aactcaggct taaccgaacg ggctaaagag acggccaatc
    12001 cctttctgat caaaggtctg gaacggctcc ttatcaaaaa tacccctgtc aacgtattct
    12061 tccaagtatt ttcctacaaa catcacagaa aaagtaacgt tctttcaagt cggtaatatg
    12121 tttacgaagg tagtaaaggg gtgctttatt ctaatttacc aaatcctcaa cgattgtaac
    12181 aacatgtgat gtgataagcc taagataaaa atggtacaga ctctagcatt caagagtttg
    12241 aagctttatt tatattctaa tgctgaaaag actagagttt gtctaatggc tgtgagacga
    12301 tcctctaaac catcaactca aatcatttct caaacagcta aaatcctgtc tccttcaaaa
    12361 aaacatgtgt tctatctgac acagtccaaa gtttagttgc cttttagaca gcacaagaat
    12421 catcaggact aattctgacc agcatgtcac atacctcatc tacctaaccc atacatacgg
    12481 taaaaccaca tagagcaatg attacggtta ccaaactctt agtcactgaa tcaatagttt
    12541 ggtaggctct tttagtaatc gttaataagc ttagcaccaa gaacctgctc aaagtgagcc
    12601 aaagaccact cataagattc ttttgtaagg ctagcgacag ccgatttaac aatctctaat
    12661 tgataaccaa gatgataagc gtcaatagca gtatgtaaga cacagatatc agataaaact
    12721 cctgttaaca ctaattgagt gatacctctt tctcgtagtc taatatctaa atcagtcccc
    12781 gaaaaagctg aataataacg cttatcaatc caaaaaactc tgggatgttg cttcatataa
    12841 ctgtaaactt cagctagtgg accataaaga tggcgtccag tagttccttt gatattatgt
    12901 gctgcaaata gcttactctc aggatgccaa gaatcatttt gatcatgaca atcaatagca
    12961 aaaaaaatat agtctccttg atcaaatgcc gttttagtta cctctgctat tttagtggca
    13021 atagcctgag cagatttacc tgcacttaat ttaccatcat ctgctacaaa atcatttgtg
    13081 taatcaattg aaatcaatgc tctcatcact atctcctaaa cagggaaacc tctcccctta
    13141 tctcttatat atggcattgt atcagttttt attacaggta tcaagacatc tatttgcatc
    13201 taccattaac agcaaaaaac atctcttttc aagagatgtt gtctttttct atttaaaatt
    13261 cttttaattt agcaaaaata ccttcgttga taactttgag gtatgtccct ttcataccaa
    13321 gagaacgact ttcaataatc cctgcacttt ctagtttacg cagagcattg acaataacag
    13381 aacgggtaat accaatacga tcagcaataa cagaagctgt caatcgtcct tcgttaccat
    13441 ctaactctcc aagaattgct gcaacagctt tcatttctga ataagaaagc gtattaattg
    13501 ccatgttgac cgctgtttgt ttacggatgg tgtcttctaa gttttctgtc tgaagattta
    13561 atagttgaat ccccacaaca gtacttgaga tctcaaccaa aatcaaatca tcatcactaa
    13621 actcattgtc attacgccag ataatgagtg atccaaggcg catccctcca ccataaatcg
    13681 gcgcaatagt cgttagacct cctggataag tgtctttaga ctcaacaggg aatatagtca
    13741 attcattttc gacagaaagg ttagcttctg tatcgtaaac tcggctagca gcctttacat
    13801 aagtatctgg aaattgttta gcttcaaaaa attcctcaac acgatcagtg ttagttttat
    13861 atttcatggc ataaccaagc agtgtgccgc cgccattgat aatacaagca ttgcagtcaa
    13921 tgatatctgc taggcgagat gccattgtgt tatacggtaa ttctgtttct aggctatcta
    13981 cggaacgctg caaaatagat gtgattttac gagttttttc taataagtta ggcatttttt
    14041 tccttttcct ttgaattatt tgcgctttca ttataacaaa gctaactcgc ttttgcaagg
    14101 aattatcaga aaattttcta ttcttactac aattccaact attgatgcct tattatcact
    14161 tcatttaaag gagataagca ctagcttgtt agagcatagg gtcacattct tttaagaaac
    14221 gctattttta ttaatcaaag atgagcattg cattaacgtc tatactggta taagacacgt
    14281 gtaatctttt cttggacatc ttctaattct tctacacttg gtaggtaaac aatacggaag
    14341 tgatctggat ctttccagtt aaaaccacgt ccatgtacca acatcacttt ttcttgcttt
    14401 aataactgta agacaaattc ttcatcatca tcaatacgat acatctgacg atcaattttc
    14461 ggaaataaat aaagacctgc ttcaggttta actgccgata agccagggat agcattaata
    14521 gcttcataaa taaaattacg ttgctcaaaa atacgccctc ctggcagtaa cagtgcatca
    14581 actgattgat gacctcctaa ggaagtttga acaacttgtt gggctaaaac attggagcat
    14641 aaccgcatat tggcaagcat gtttaaccct tcaatgtaac ctttaacatg gtctttagga
    14701 cctgataaga ccatccatcc aacacgaaaa ccagcaatac gatgagattt ggaaagacca
    14761 ttcatagata cacaaaaaac atcaggtgcc aaacttgcaa tagcaatatg ctctttacca
    14821 tccatcacca aacgatcata gatttcatcg gcaaaaataa tcagctggtg ttctcttgcc
    14881 aaagcaacga tgtcttctaa aatctcctta ggataaaggg ctcctgttgg gttattagga
    14941 ttgatgacca caatagcttt ggtgcgactc gtgatttttg atttgatatc agcaatatca
    15001 ggataccaac cagcttcttc atcacaaaga taatggaccg cttttcctcc accaagactc
    15061 acacaagccg tccataaagg ataatccggc attggtacta aaacttcatc gccattatct
    15121 agcaaagctt gaagggatat ggatatcaac tctgacacgc catttcccaa ataaatatct
    15181 tcaatgtcaa catctgggaa gcccttgagt tggcaatact gcatgatagc cttacgcgct
    15241 gaaaaaatcc ctttactgtc agaatagccc tcacttagcc tcgcgttgac aattaaatca
    15301 cgaatcactt catctggtgc ttcaaaacca aaagcagcag gattgccagt atttaaacgc
    15361 agaatttttt caccactcgc aatcatgcga ttagcttcat ccaaaacagg ccctcgaata
    15421 tcataggcaa catgttctaa ttttgatgat ttttcaataa ttttcatagt ctcatacacc
    15481 tcgtattcca tattataaac caaaatactt aaaatagaaa gaatttatcc atcaaagctt
    15541 aggacagcta atcgttttaa cacaggtctt atgagacgat aatacagtct ttagtttagc
    15601 aaaaataatg gatcgctttc aaaatgactc aaaaaagagt ataatgaaaa aaagaataaa
    15661 agctattctt gtcaaactgt taaaggagga cagttctatg tcactaaaat ataaacgtat
    15721 cctcgttgct attgatggct cttatgagtc tgaattagct ttcaataaag gcgttaacgt
    15781 agcactacgt aacgacgcta ccttactact agtacacgtt attgataccc gtgccttgca
    15841 aagcgtagct acttttgata cttacatcta tgaaaaatta gaacaagaag ctaaggatgt
    15901 tttagataat tttgaaaaac aagcacagat agcaggaatt acaaacatca aacaaattat
    15961 tgaatttggc aaccccaaaa acttactagc tcacgatatt ccagatcgtg agaacgctga
    16021 tttaattatg gtaggagcta ctggtcttaa tacctttgaa cgcctcctta ttggctcatc
    16081 ttctgagtac attatgcgac acgctaagat tgacttactt gtagtccgag atagcactaa
    16141 aacactctag tctattacaa ttttcaaaca ccaaaaaaca agcagcatct acaacgaaat
    16201 tgcttgtttt tttgtgctga gctaagtcta gtcaatatct ttttatttct tgatatttaa
    16261 aagagtaaac ctctatttat cgaatcgttg tagtgatttt tgtaattgtt tgtctaactc
    16321 tttttttatg gctacttcag gtgcgtgacg ctcttgccaa tagtcaggtt tttgaatttt
    16381 atgggtaacg gggtcaaagt gtgccttgcc atctggaaaa attttagcca tatttgcttc
    16441 atgtactgct tcaaatatag gttgtggatc tactcccatc agtacaaaag aaccataagt
    16501 aaaataaagc aaatccgcta aggcatcaac ttgcccaatc aggggcgttt caacatgttt
    16561 tttagcttgt accttattag ctgcttggtc aacagcacca tgcaaatcga aaatagcctg
    16621 tgtaaattgt tgttggtctc ccttgcttgc tgcgtaaaga aactcaacaa tttcttctac
    16681 tttaaagcct gacctataac cagcttctga aatggtataa ctacgcggtg tttcaatagt
    16741 atctgagtcc atcagacgat gaaaatcttt gactttatta aaattttcat cacggctttt
    16801 aaagctcttc tctatatcaa aatggatgag accgtagtga gctaaggctt tggaaatccc
    16861 atcattatta ttagagtcgg tagtgaaatg ggctccatct tttaccacag tttcagcatt
    16921 tcccatagca ataccgatac caactcctga taacatttca aggtcattat ctgaatctcc
    16981 aaaagccatc acttcagaca agtcaaatcc aaacatctct cccaaacgtt caattccttt
    17041 tatttttgat tgatcaacag agatcagatc caaggaataa ggactacttc ttgtaatttt
    17101 tatatgaggg aacttctctt gtattttctt agtttcagct tgtgacgcta ccagaacaac
    17161 ctgataaata ggctcccgca taatagttac taaatttcta aaactctgag gcttgattcg
    17221 gcgaatcaaa tgcttaaaac taccctcaac tgttcttgcc caacttttgg gcacaaaact
    17281 actaatgact tgtccaaatg ggctagtccc catatcaata atacgcgatc ctgctaatcc
    17341 agaagctgtt ccaagagaaa tttctcgctt tttttcgttg gcatagcgaa tcactttgta
    17401 aatcatcgac tttggcaatt gattctgata taagacctta tctcttgtta agatatattg
    17461 cccattgtaa gtaacggcaa aatctaatcc aaaattttct agaaaaggtt gtacaaatcc
    17521 cggtccacga ccagttgcta aaccgaccat aatgccttgt tttttgagtt gttggatggc
    17581 tttttgcgtt gttttttgga tatttttacg atcattgaga agggtcccat caatatcaaa
    17641 aaagactgct tttactgtca aaaccttctt ttgcctcctg tgtttatgat agaatagatt
    17701 atatcataaa taaaaggaag tttgacaatc aaatgaaaaa aatcctagtc ttacacactg
    17761 gtggaaccat ttctatgcaa gctgataact ctggtagggt tgttccaaat caagataatc
    17821 ctatgacgaa aatacatgct gcagcccaag atattcagct taccgttagt gattttctaa
    17881 atcttccgag tcctcacatc acgcctcacc acatgttatc tatttatcat catattcaag
    17941 aaagaactga tgtctttgat ggtatagtca tcacacatgg aacagatacc ttagaagaaa
    18001 cagcttattt tttagatacc atggcattgc ctactaatat acctgttgtc ctaacaggtg
    18061 ctatgaggtc ttctaatgaa gttggtagtg atggcatata taattacctt accgcactta
    18121 gagttgcaag tagtgataaa gctaaagaaa aaggggtact tgttgttatg aacgatgaaa
    18181 tccatgctgc taaatatgtt actaaaacac atacaaccaa tatttcaact ttccaaacac
    18241 ccacacacgg accgcttggt atcatcatga aaaatgacct actttttttc aaaactgctg
    18301 aacctcgtat tcgttttgac ttgagatgca tttctggaac catccccatt atcaaagcat
    18361 acgcaggtat gggcgatggt agtatcttga gtctattaac tccaggtagc attcaaggtc
    18421 tagttatcga agctctaggg gcaggaaatg tcccaccatt agcagttggg gagatcgagc
    18481 acttaattac tttaggtatt cctgtcattc ttgtttcccg ttgtttcaat ggtatggcag
    18541 aacctgtcta tgcttatgaa ggtggtggtg cgatgctaca agaagcaggt gttatgtttg
    18601 taaaagaatt gaatgctcca aaagcccgtc taaagttatt aattgctctc aacgccggac
    18661 ttactggtca agagctaaaa gattatattg aaggataatc tagcttcctt tagaaatgtc
    18721 ccactaaaac atattagtgg gacatttcta gtactttaag ctttaaatta ggacatctcc
    18781 taaatgtcta gaataaacaa ctatgtttca aactatgaga ttgtgcactc ataatcattt
    18841 ctataacagt ttgagaccag tattccaata aatccaactc ttagcaatca gataccgggt
    18901 aaacaagtct ttattttgtc tcattaagta tgagcttact tgaataataa caaaactact
    18961 tgcttatcct tttttagtaa tgatgaagac gacctttttc taagaacttc tttgtctttt
    19021 aaaataaaca aagcacatat taccctttat tttagttctc gtttggaaaa aagaaagaca
    19081 ttgcctaaaa gataacaaag agttaaacca aaggccacta atatgctagt actagaaagg
    19141 tgtttatcac caagagacaa ggataggtgt ttaaacatca aaactgggct aatatctaac
    19201 ttaaaaaaat ggtttgctaa agtagcagat actttatcaa aaagaaggac ataaagtata
    19261 taagctgtga ttgactgata agttttacga agtatattaa acaaaaattg acacaaagca
    19321 ataatagcaa tataaaaagg cagttgttta atcatccgat ctatgactat tccatagtat
    19381 gcttgaccag taaataaatg aaatgctaaa gcactaagaa gataagttaa actaataaat
    19441 aaaagagata agccaaaact aactagcagt ttatagatta taattaaagt acgattttgt
    19501 tgtttgacca caacattatt aatcgtacgg tagttatagt catcactaaa aaagatacgg
    19561 gctggtgtta aaaagaaaag cgtcacaaaa tcagtaataa tattaatgat ttgtatcatg
    19621 atgacttggt taggtgtctt gcgaaaacta taggctacac caacagcaat gacaacaagt
    19681 agcatacaag aaaatagagc taaacgctct tggcgtatcc gaaataaatc tgctttaaga
    19741 taggaaatca taaaaacctc tttctaaatt aatggtgatg ctgcatcttt acctaacaaa
    19801 tcgaggtaat aatgttcaaa gctcacttga tgatgataaa tgtcaaaaat ctcaacaggc
    19861 agatctagaa caattttgat aagctccatt actgataaag ttggttttat tagtagcatc
    19921 tgaccatcag tctcaactct aagccccaat tctaaaagtc tattttttac cagctgatca
    19981 tcgcttgtat gaagggcaat ttgtactttt acttgagctt taagctctgc tttgtccata
    20041 ctcttaataa ctttgccttt atgcataatc acgtaacgat caacaactaa gtctaattct
    20101 gataaaatat gactggaaat caaaatcgta ataccatagc aatctcttag gttcaaaata
    20161 atctgacgca tttctttgat tcctgctgga tcaagaccat taatgggttc atccaagatt
    20221 aaaaattctg gaaaatccag tatcgaaaga ccaatagcca aacgttggcg catccctaaa
    20281 gaacaatctt tcaccttttt ctttttgctc actttttcta acccaataag ttccaaaacc
    20341 tcatgtatgc gctcttttgc atcagctaat ctcaattgca acgctgcata gtaaagatta
    20401 tcatgagctg tcatattggg ataaagtgtc ggtgactcaa taattgatcc cattcgatag
    20461 ggttgtaact gtttgatttg ccctgaatct tttccaatta ggccagataa aatacgcatt
    20521 aacgttgtct ttccagcacc attttgaccc acaaggccgc aaatttctcc tttgtaaata
    20581 tcaaaagaga tatcacttaa aacctgattt ttaccatagg atttatttac ttgctcaata
    20641 cttagtaaca ttgattgctg tgtcattttc cgctcctttt ttgtacttat cgatcaatac
    20701 aatatcttac acataataac atctgtaaac ggttgtgaca agttcttctt tttattaaaa
    20761 aaatataaat aagaatttta ataatatgat tattttagca ataaaaaagt tatactgaaa
    20821 atgggttaat actgcttcac atagcagtct catcgtaaag cataagtaaa aaaggccaga
    20881 aatagtgacc tctttatact ttataacagt ttatctcaaa actaactaaa tatttgtaaa
    20941 acaacgactt gttttaagtt aatcataaac ttcttttttt ctaatatttt gtgccactaa
    21001 ttgccactgt ttttcatata tccagttagg atcagaaaca atcgctgcag aaactttgcg
    21061 tgcttcttct aaaataggat aatcctcaac gatatcagct acttgaaatt ctggaattcc
    21121 agactgacga gtaccaaaga tttcaccaga accacgcatt tttaaatccg actcagctaa
    21181 aacgaaacca tctgtcgttt ctgtcatgat tgtcattcgt tttttccccg aatcagtttt
    21241 gggattagcc actaaaacag cgtatgattg tttatatcca cgaccaacac gcccacgaag
    21301 ttgatgtaac tgacttaatc caaaacgatc ggcatccata ataatcatga tcgttgcatt
    21361 tgggacattt acccctactt caataactgt tgtggatact aaaatatgac tttttttatc
    21421 cttgaaatct tgcattatag catctttttc atcatttttc atacgtccat gtacaagagc
    21481 aaccttagca attccttcaa aataagtaga taattcagca tgcaatgcta ctgcattctt
    21541 taaatctaaa gcttctgatt cttcaatcaa cggtgaaatg acatacactt gagcatcttt
    21601 ttgcaattca ccttttaccc attccaacac agtacctagc tgctcgtgtt tcacccagcg
    21661 tgtcataata ggtttacgac cggcaggtaa ttcatcaata atagaaacat ccatttctcc
    21721 aaaagctgtg attgctagag ttcggggaat tggggtggct gtcatcatta aaacatcagg
    21781 attttctccc ttttcacgga aaattctacg ctgtttaaca ccaaaacgat gttgctcgtc
    21841 tgtaatgaca agccccagtt tatggtactg taccgagtct tggataagag catgagttcc
    21901 tacaatcata tcaaccgagc catttgcaat agctgctaaa accgtacgct tgacagctgc
    21961 tttcataccc gaagttaata tagcgattga taaatctgga aataactctt gcagactaat
    22021 gtagtgttgt tcagctagga tttccgttgg aaccatcaaa gccgattgaa aacctgctgt
    22081 ataagctgca tacattgata gaccagcaat gactgtcttt cctgatccta catctccttg
    22141 caataaacga ttcatatgag ctcccgatga catatcagat aatatgtcat ctaaagagcg
    22201 cttttgagca ttcgttagaa taaaaggtaa agaggaaatc tttgtctcca tagcacgttt
    22261 actataaaga ataggcaaac catttgtttc agatttattt tcggctttca aaacttgaag
    22321 gttcatttga aagtaaaata attcttcaaa tttaatccga cggagcgctt gcttatactc
    22381 tgtgatatct tttgggaaat gcatagctaa acaagcctga ctacgaccca tcaatcggta
    22441 tttttccaat aaagtagctg gtaaattttc cttcaattcc aaatgcgcat cgatttcaaa
    22501 agctgactta atagctttaa tcaaagtaga ctgtgaaatt ccctgagcta cgcgataaac
    22561 aggttgcatg tcatcttcaa cttgagctaa aaccttcatc ccagtaatag ccgatttagt
    22621 ggcatcccat ttaccaaaaa cagctacctc ttgaccaagt tctattttat cagctaaata
    22681 gggttgatta aaaaaactaa catttaagac agcttcccct tgacgcaatt tgaaacttaa
    22741 acggttacgt ttaaaaccat aatattgtac attagctgga gtaacgacta agcctgtaat
    22801 gactgctttt tcaccatcca ctaaatcaaa aacagatttt gatttaaaat cttcatagcg
    22861 aaacggataa taaagcagta aatcttctac tgtataaata tctaatttct gaaatttttc
    22921 tgctgatttt ggtccaaatc cctttaagtt ggacatagga gctgttaata tcattatctt
    22981 tttcccttca caaaaactct tgtcagattg aagacaaagt ttgtcgtgat actttcctta
    23041 ggtggtgctt acggcagcga cgttctttgg aattccatgc ctttattttt gagcctgagg
    23101 tctcaaaaat cccgagtggc gtcaatacga gattgacgcc actcttttac cacagcaaaa
    23161 agcatctgtt ttggctcact ttgtgtgtaa aaatcggaaa ccgaatgtca aatcagcaga
    23221 gctattcatg ctttttgagc ataaaactgg ggttgtctac gttctgactc ttgtatctat
    23281 tatacaagag ttcctattta ttttcagata aaagcctttt agtactttta aacagttcta
    23341 ggggctcgtt aaggtagcat ttgataaatg gtatcgcaga cactacttag aagttcttca
    23401 tcatgtgaaa tgaggatgac aaccttatgt tgggtcttca gctgcatgag aagattagct
    23461 aaagccttca tttgtaacaa atcaagtccg ctacttggct catcaaaaat taagatatct
    23521 ttatcagcca aaagactagc ggcaatcatc actctttgtt gctcacctcc tgacaaacta
    23581 gctggatgac gttctaaaag agtcgttaaa gataaccgct ctattacttc tgtcgtccgt
    23641 ggatgtcgtt catggcccaa gttgacttcc tttgaaaccg attctgcaaa tagttgcaaa
    23701 gaaacttctt gcaagacaat actagtcttt gataaacgtt gcttggcaga taaaggtatg
    23761 ccttgaaact taatagttgc ttttttatcg tctaagatac cagctatata ataaactaat
    23821 tgcgattttc caagcccgtt tgatcctgta atgccagaaa tacttcctac agcaaaacta
    23881 agctgttcaa tacatctaag tattttgctt cccgctctaa ctgttagatg ctcaatacac
    23941 aggctatcat ctgggcgata atgttgactc tcaatcttac cagctaacac aggttttagg
    24001 tcagacaagt ctaagcgacg tagtcccata tcttgccgtt gttcatctgt caaggctagc
    24061 aaattttgtg ttgttaactt atctgttaat ctaccatttt taaagtagaa aaagttatct
    24121 gccaaatcca tcaagtaatg taagcgatgc tcggctacaa taatggtttt tcctgctgct
    24181 tttaattggg taagataggc tttaacagca gctatgcctg cactatctaa gttagcagtt
    24241 ggctcatcaa aaagcataat attagtacct tgcataatgg ccgttgcaat agcaactctt
    24301 tgtttttgcc ctcctgacaa tccaaacata tccttgttaa ggagctctgc aaaagcaaaa
    24361 tcttctgcta aagtccaaag acgcttcatg ataacctttg catctaaacc ttgattttca
    24421 caaggaaaga ctagttcgtg ttggacttcg cgatagaaaa actgactggc tggattttga
    24481 aaaacagagg ccacagatct agaaaatgtt tcaacactgt ctctgcctgc ttggcaatca
    24541 gccacatcta gtctaccttc atattttcca gcataataat caggaattat gccattaaga
    24601 agttttaaaa aggtagattt acctgaacca gaaggtccac acaaaacaat gaattgtcca
    24661 gaggcaattt gacaagtcga tatctgacaa gctggatttt tttgatcatg ataggtaaaa
    24721 acaagttgtt ctgctgaaat cattgcagta tcgtgatgat tatgataaca gtaatccaaa
    24781 tctgcacccc ccaatctttc catgttaagt gtgagctaaa gcattcactg gtgcctttgt
    24841 tgactgctag ccctttagtt agactagcga tagttagttc ttggctactt cttatcaaag
    24901 ataaaagcaa tggaaccatt aaatactcca agtattgttt aggtctgatc aaaatagacc
    24961 attttgttaa aataatcccc ctgattttta aagagcgatg aataacacaa cattcttgtc
    25021 taatcattgg tatgaaacgg cacataacgg ccaaggtcaa tagccagact tctgggaaac
    25081 gccatttgcg taatccatga accaattcgt agatggtagt tgtcttaata gtaattaaac
    25141 ctgctagtaa agaagggaaa actaaccttc ctgctattga gacaaaactc aataagtggt
    25201 caagataaga agggaaaatc gatagcggga ttacagatag accgatcatt aacagataaa
    25261 caaccgccaa cttgaacgct agctttttct tatttaaagc agacaaaagt aataagagaa
    25321 aaataacaat tataaattct aaaaagccat caacacgaaa aaagaagcag gcattggcaa
    25381 gtaccaacaa aagcagtttg gtgcgaacat caagcctcat gataacaatc ctgatttgat
    25441 aaaatgtttc tttagtaaat aatgtgcaaa aactgaccct aataaggctc ctgcaagaac
    25501 aattcctaca aaccaaataa catgccctaa actaaaatca tacataatgc gattgacata
    25561 ggtcatactt ttaccgcggg ctaacaaact ttcaacatag gcatctttca acaaccacat
    25621 cagcaaaata gggccactat tgacaaaagc aaaaaccata taagataggt cattaaaaaa
    25681 ccttgacttg tattttccta aagacgcaat aatatccgct attaaaccga aaataatgct
    25741 gggaaacatc gcggcaaaaa agtgaccact aaggaagaaa aaacctccca tcatcaatcc
    25801 taataatgtt attggcccaa atgtttgcaa tttagcaatc aaaagaaaat aaattgttcc
    25861 ccccagtaaa gctgcaaagg caggggcata taacatattt cctgagcgat caaaaaagat
    25921 gttaataaac gtgcctagac caacacaaat aaagtagagc gcggcaaatg cgcctgttat
    25981 cataatatct tttattgtta actgtttcat tttttattca cctcttttag ggaaccattt
    26041 tttacgcaaa atagatgatc aacacaagct agggttgatg gcctgtgaga aattaagaag
    26101 accaatcctt gacaatgtgt tttaattaaa tcaagcaaga tagcttcatt tagagaatct
    26161 aaatttgacg tgggttcatc aaaaatatag caactcgcat ctttcaataa agctcgcatc
    26221 aactctaaac gttgaccttc tccagctgaa aagtcagaag gactcttgat aatcgtatcc
    26281 aaaccttcct tacaagctaa cagtctgtct ttcataccac aagcctcagc taaattccaa
    26341 atggactcat ctgaaatatc ttgacggcca aagataagat tttcacggat agactgttgg
    26401 aaaagctgcg ctgtttgtgg cacataagca atagtatctt gtaatttagc agcatttagt
    26461 aagcaactat tcctatcatt aagaaaaata tctcctgtct tccaattata ccatttcata
    26521 attaatttca ccaaagttga tttaccagat cctgattcgc ctttaatgcc aataatcccc
    26581 ttttcttgaa aggtaactgt taaatcctta aaaaccagct cttggcgctt tggataagca
    26641 aaactgaggt cctcaaaaga aacactcctt aaacgatcta tttgttttgt gccttcatct
    26701 actatgacat tttcgtctag aaggtcaaaa atatttcgag ccgcattcat agcacgctta
    26761 aaacctaatg gcaaacgtcc tagttctaaa aaaggagaaa acgaagcagt gaaagcaata
    26821 aaagttaata agcctttatc aaatgataag ctgtcatggc atatcccatc aaaaaccata
    26881 taagaaaatg ctaagatcat taagccaagc cagaaaaaag tcaatgccat ttgcaaaaat
    26941 tgggcttgcg ctacgttacg atcaagagca tttacatgat tacttttttt tattaatcgt
    27001 tcaaattgct cgtctaatac ctgaaattgc aaaagatctt tgactgatcg taaactctct
    27061 aaaaaataag acaggtaatc ttttcgacct tcattttggc tttttagtaa aacctgtaaa
    27121 atattagcaa aataaatggg tataacaatg gctaaacaag cataggttgc caaagctaat
    27181 aaggctaact gccaactact ttgacaaaag taccagaaca ttaaacctgc agacaatatt
    27241 gctgtacaaa taggtgcgat tgtgtgggca aaaaaaactt ctaatgcctc aatatcttct
    27301 ccaatcattt taagcaaata accactgtct tgactatcca agcaagctgg agaaagagct
    27361 cttagtttct taaagatcaa gttcctaaaa gctgctaaac tatgaaaagc aacaaaatga
    27421 ccaaaataat gctctccata acgaacaaaa cctcttaaaa aggctagagc aatcaaaaga
    27481 tataaagcta atattggaat cacttcttgt ctaatagcta gtagtcctaa ataagctatt
    27541 ccagttggaa tacttaccgt gatgacaaaa cccataacag caaagccaac agccaagata
    27601 atccaaggta gcagagtttt cattagggtt aataaacgcc aaaccaggct taaggtagat
    27661 ctgttaggtt tagccataaa tacttgcctc cagtcttgct tgagtatcaa ctaggtgacg
    27721 ataagttggt tggtcccgat aaaggtcgca aggtttgcct aaacaagcag gctgccctgt
    27781 gtttaaaaag agtacttggt tagctccttt cagtcgagac atcttatgag taatcacaat
    27841 aactattgct gtcttagcta atctcgttat taaattgtca ataatacgtt cattttctgc
    27901 atctagacta gatgttgcct catcaaagat ataaagagac ctcttactta atagagctct
    27961 tgcgcaaatc acctgttgct tttggcctgg tgataacagg ttaccatttt caccaactat
    28021 tgtgtcaaga ccatctggta gccagttgat gaagcttaac aaaccatgtt gatctatcca
    28081 atctaagatt tcttttttag agagatttgc tgctaacctt aaattatcgt aaatgctacg
    28141 gttcaataag gtagattggt ccgatacata aagaacctgc tggttgatag tttcttgcga
    28201 caaattgtca ctgtctaaac cgtcaaataa aatatgccca gtcgttgcag actggcgttt
    28261 caagaggagt tgagctagac ttgtttttcc ttgtcctgac acccccgcga tagctgttag
    28321 ttggcccttc gttaatgtca tggtaacccc actaagcact gtttttttct cataagctaa
    28381 agaaatattt tggatgtcaa tctggttaaa gtttattgct gttttactct tgttatcttt
    28441 tcttgctgga acactatcca agaaactaaa gatacggtca gccattttgg tattcatcat
    28501 gaccaagtgc atgccataac cctgctcacg aatcggtgta aaaaattctg tagcaatcaa
    28561 gagaaaaaat aggaaattaa aaaaagataa ctggcctgtt gccaaagctt gaacggctaa
    28621 aaaacctgac aaaccaattc ccagatacat aactgcatcc atataaccaa ctgcttgtaa
    28681 ctgaaagcca agcaaagaca tggtagcctt tcgaaactgt tctgccttac ccgaaaattc
    28741 ttgctcgtaa cgttctgttg cttgataaga atacagtgta ttaagacctt ttaagtcatc
    28801 cataaataaa ttaccaacat ccatataaga agaccaataa tgactcataa tttgcttaga
    28861 ccgcttttgc atagcaacga ttgaaagtgg aatcagaggc agaactccta aaaagacaag
    28921 gcctgccaat ggataaatta aaaagactag tatcataata gttgtgcagt tccacttggt
    28981 tctcatagac aaagacaaat agtaaccata ataagtatcc aaactatcaa tcccctgtga
    29041 agccaacgtt aaaatatcag catcactggc atgagcatca aattgcccgt ctaaatcaat
    29101 aaaagcctca aagaaagatt gtttgagtga atctctagca aattgtgaag cgatcccttg
    29161 cagttgcttg cctaatatag caagaacaaa gcctaccaca tttaaaagta ggagtaaacc
    29221 tgccaagcgt cctaaggcaa tagcatgacc caaaataaag gtcgaaaacg ttttggcaat
    29281 gaggtaaaaa ctgatcatcc tcatcacaaa ttgtaaccaa gataaaaagg ctgacacata
    29341 aagcaaatac ctttttggtg caattcgttc acgtaatcgt tttaacagtc ttttcctttt
    29401 tccccttgat attgtatctt ctgtttccat catctgttct tgttcctatc tctcctttga
    29461 gttctaatac cattggtttc attgaccaat gaagtgagga caaactgttg accatttctc
    29521 tcaacaaagg gcaattcaac accaaagaca tctctgataa actgttgatc aaggaggtct
    29581 cttggttgac cttgggcata aagtcgccca tctttcagtc caataagatg gtctgaaaga
    29641 gacaaggcct gattgatgtc atgtaatact aacacaatcg ttaggcctag ctcttggttg
    29701 attttagtaa tcagcttgag aatgtcaagc tggtacttaa tatccaaata agtcgttggc
    29761 tcatctaaaa aaataatatc tgtatcctgg gcaagggcca tggcaatcca aaccctctgc
    29821 tgttcaccac cagaaaggtg ttggatatca cgataaacat aatcactcaa agccgttact
    29881 tctaaggccc aagcaaggcg ctcctcatct tctttggtag tagttttaaa aaaagaacga
    29941 cgggcaagcc tagccatggc taccaattca cccactaaca aaccttcgac cacttgatgg
    30001 tattggtgta ccactgccac ttttttcgca aaagccttga gagaaatcgt tgctaattct
    30061 tcctgctcaa gccaaacctg cccttgtttt aacggaaggt ttttggttaa taattgtaat
    30121 aaggttgact tgccactgcc atttgccccc ataatagtgg taattttccc ttttggaatg
    30181 ctaaaggtca ggtcatctaa aacaagtttt tcctcataag caaaggaaag gttttgcacc
    30241 tgaatatgac tgctgttctt actcatataa tatcagacct ccttagcagg taaataaagt
    30301 aaggcccgcc tacaatactc attataatcg cagggctaat ttccaatggg taagcaagac
    30361 ttcttcctaa agtatcggct agcaaaaaga caaaggctcc aagcaaagct gaaaaaggaa
    30421 ttaagatttg gtgcttactt ccaaccagca agcggctcat atgagggaca atcaagccta
    30481 ggaaagaaac cactccaacg atcgaagtgg ctaccgaagc caataaaaca gcaaccaagg
    30541 aaattcccaa ccgtaacgct gtagcatcga ttcctaaatg acgaatcacc tgatcatcta
    30601 aaagaagaag gttacaagtt tttgacaata acaaagctag taacaagcca atgaatgtat
    30661 aagggaataa aacccctaca tcagcccatg ttttttgact aatatgacct gctaaaagag
    30721 cattgaccat gggactagct gaggtgaaaa agctggttaa agcagttgat aaccccataa
    30781 ataaagcatt aatagcaatc cctgttagaa taagccgaat aggattaagc cctttcttcc
    30841 atgctaaacc ataaatcagc aggaaagaca ctccgcctcc taaaaaggat acgattggac
    30901 catacagcag caactgcggc agaagtaaac tagagactaa aaccataaaa ctagcaccac
    30961 tacaaatccc tataatagca gggtctgaaa taggattttt caacactgct tgaaaaagaa
    31021 ctcccgaaac agctatccct gctcctgcta ataaagcaat gacaattctt ggaaaacgca
    31081 aatcataaat caaagccact tgggggtcat aagccacaaa cagtcccttg acaattgccc
    31141 cataagaaac cgccaaacca ccaagggata aggcaataac cgccaaaaat aggaggctga
    31201 gaattaaaag aactagataa agaccacttc tgaaacgttt tttagccagt agggattgat
    31261 ccctttgtaa atctgatgct gtcatgttac ggatgatctc ccacgtggtc aaaaagctgt
    31321 gttaaggtgt ccaaggcttc tgggtagttc aatttagcac tcatgccaaa cagggtattg
    31381 tccaaatcat agactttccc ttccttgact gccgtaaaat gtttccaaat atcattttca
    31441 gcaaattctt tgtcaaacat cacttttacc ttgtctggaa tggcatgagc tgttcgtaaa
    31501 atcaagtcag gctccttagc cagcatgtct tcaggattag ctgatagaaa ttctttctca
    31561 tctgactgat aaacattctc accacctgcc aagtccaaaa gattccctac ataagattgg
    31621 ttcgtcgcca ccaaataact acctggcaag cccataagaa taagcacttt aggctttttc
    31681 ttccccttac gtttagcttg gaaagcacga taatagtcct ggtattgctg gcgcaattct
    31741 tttgcttctt gttgacgttg gaaaaggttc cctaaatcat caatggactg gtacatgccc
    31801 tcaacacttc gtaagttcaa aaaaccatac tcagtatcca atttttgata cttgggttcc
    31861 aaatcttctt gtaaagaatt gggactcaaa atccaagttg gtttcaaaga agcaatcaac
    31921 tctatatcag gattcatggg taaacccaca cgcttaacag catcatagcg tttaggaagg
    31981 gtatataatt tactatcaca aaccccaacg aggtctaaat ttaaacggtc acagatatca
    32041 accacagcaa ccgaagtggc tacaattctc tgctgttcag tctctttagc cgttttaggg
    32101 tgctgattca cacaagctac caaaaagaag gccattaagg ctagaccaat tcctttacat
    32161 cgttttatca ttttttttcc tctttttcca aacccataca gcaaaccctc ctaacatcag
    32221 aaaaaaagtt ggaaagtagt aaatcatgat tgataagtct tttttagacc gaaacttatc
    32281 ttcttttttt aactctaaag aagtcgttaa gcccatctta gaaggaagaa tttttttatc
    32341 tgatagactc ttgttatttg atgagttggc tttaggctta ttctgagtta tcatagcacc
    32401 tgtgtgagac tcatcttgac tttctcctag ttttgtatca acaggctttt gactgtcttt
    32461 tacttcttga ttttgagaat tgtctgtttc agtaacaagc tgggccaaca tattacctga
    32521 atacttttgt attaactctg aagctgacag gtaaaagacc acttctctgc ccataggttc
    32581 aacaaacatg ctgcctcgaa tgatactatt tacagtaggc aaactaatag caatatctag
    32641 tgttgtccca ttggtatcag tacctttttg ggtgatattg taatcaactg cctgaaagct
    32701 tccagttcct ccaggttgta tccagaactg ataattgccc gaataatcag ctaagctcat
    32761 acgaaaagta agaacgatct ttccagcatc agatacttct agcatggcat cactatagac
    32821 agttccttca accatacctt gaccaatatc aaaggaatgc tcccctccgc tatcttctat
    32881 ctgcccagat atcggatgac gataatttct ttgaataata catccataaa tttgaccttt
    32941 atctgcatac acaagatttg tcattgtcga taaacttatc atgaacacta ctattacctg
    33001 caacaattgc tttattacta cctttgtcat atgctcctct tgtctatctt ttcttaaaca
    33061 tcttatttca ttttttaaat gaatcccatt ttataacatc tccaaatgtg aaaaacacac
    33121 ctatcttgcg actacttcaa cctgtatcag gagtcctgtc ggaaataggt atgtttttag
    33181 ctcttgctga ctagcttttt tgttatttca cttggtacta agtttcttat ttaaataatg
    33241 tctttcgacc aataatgaat cccagagcta cgatcataaa gctagataga cctgcaatta
    33301 agtgataacg agagctactt tcttcaccat ttgattgttg attggaacga tgtttcttat
    33361 cagatttttt agtcttagta tcttttgctg ttttaccttc aattgatgtt tgatggtcac
    33421 gcactaactg cttcaatttc tctgccttat cagtatcatc tgtcttagaa gtttcttgag
    33481 ttgattggcc ggttgctttt ttagccagga gatcagttaa gttagcaata ccagtagctg
    33541 ctgaaggagg acttgtaggt gttttttctt gttgacgatt ttgaggtcct ttcaactgat
    33601 ctgttgaagt tagatggcta ttttcttgtg gattattagt ttctttgaca acctttgcct
    33661 tctctgttgt aaggcttgcc cagtctaaac gcataaaaac ggtttgaagg ccagaccctt
    33721 ttgaaatggc atccatgata ggcacaaaga cctgtaatgg cacaagtccg tctttcttcg
    33781 cttgttcaat caatttcata cgcagcactt ttggatagtt ttttccataa cgatctgcca
    33841 atggtaggcc agttacatcc gtgaaataag acacaacctc tgcctttttt gttcgaccaa
    33901 ctggtttacc agctaaatct ctttggtaac catctacgaa atagctcaat tcaccaaggt
    33961 agcctaacat tttaccaacc tttatacctc taaactcaac ttctaaatag gaaacacctt
    34021 ttttaactac caaagtcact cgatgattaa tagccttgtt tgacatggac tcagatgcta
    34081 agtcagtttt taacatgctg gcatttaaat agtaaatacc atcacgcaat tgtttttgat
    34141 ttaatgctct aaggccgttc tcaactaaat ctttctgatg tgaatgtggt cctttcgcca
    34201 caaggatatc attagatgtc aaatagatat gttctttttg agtagcaaat ttctttgtta
    34261 ttaaagcttt gcgaatccga tatgtacctg gatcttttaa agaaaactct cccgttaagt
    34321 catctttcgg atcatttgag agaagctttt cgtcaaccgt cacatactgt ccattggaag
    34381 cttttttttg caactgaatc acaatactcc aatcgacttg catatcatta agtaaagaaa
    34441 ccgtatctga acctttttct tgtaacaatt gttgatattc ttcaacagac actagttctt
    34501 tatcaatggc agaatttgtt ttttgctccc aataatacaa atctaaaaga ctgaaagctt
    34561 gatgatattt tattttttcg ccatctaagg aagcttcaag ttttgcaata tgtttttgtg
    34621 gagtcagttt gtgttgtccg ataagagctc ttacttttgg actcacactt tttatctgat
    34681 tgaacttcac atctaaatta agcgtttcaa catctggaaa tactgattct tcaacctgag
    34741 taagcaagtt attgaaaaaa tcaagttttg ttaattggtt attctgttta aatataccat
    34801 ttggaagatt tgaaatttca ttagttgata aatcgagtac agataattta ggaagatttt
    34861 taaatgaaat attatcaata cgagtaatat gatttctact tgccacaata gtgcttaagg
    34921 cgcgcaattt ttctattgtt tttggcagta gtgctaaatt attttgagat aagtcgataa
    34981 aattaagtga tgttagaggc tctagcgctt tttcaggtat ctcctcaaga ctattttctg
    35041 cgaaacctaa tgaagtcaga cgagacaatc cttcaaatgg gttatcacaa agtcggccaa
    35101 tacgattctt ggaaagatca agttgctcca ggtgatgaag cgactggaat agtcctcctt
    35161 caagagagtg aataaagtta cttgataagt agagttctct taattgagca ttgcttttaa
    35221 atgtatcttt gtctagataa gttaaatgat tacttcttaa gttaagaaat cgaagttgct
    35281 tcatttgact aaataactct tttggaattt ccgtaatttg gtttccatcc agatgtagtt
    35341 ctgtaatatt tttagcatgt ttcaataaag aaatatcagt taactcgtaa tggtctagac
    35401 gcaactcgcc tcgaatctgt tctaattccg tttttgataa tttaccatcg ccgtctaaat
    35461 ctttgccaag tttaactaaa actttttcaa gacgttcagt cccaacccct ttttctttat
    35521 catcagtttc tacctgataa ccactccagc ctttggtaac ggtcttacta aaggtcatgt
    35581 caagtttggt gtatttgtca tagtggttta aatcactttc ttgacctccc atggctgata
    35641 ccaaaacagc acctttgtgt aatttatcca aatcatcaat aggcatggta aattcgcttc
    35701 gaatatagct accattgata tctttttggc caacttgttt acgcactgct gctgggtagg
    35761 tccctttgct ttcaatagaa aagtcaatca aaaattgtcc caaagcagta ttaagcatgg
    35821 aaatttccat tgtaccatct gctttaacca ctaatttggc tcttttatca aaagcacctt
    35881 gaagcatgga ggactcttct gagttttctt tattagcttt aaagtttagc gtataggttc
    35941 cttctgtgag attgttaata gaaacctcac ctgcttgata agactcgatg gtatctttta
    36001 acagtcgatg agtatcggcg agtagcttac tatctttgat ttctttgtaa gaatccttga
    36061 tgacttgaag tttctcagcc agatctttga ccgcgtcttt gttgctttct ttagcaataa
    36121 tcgcatccgc ttctttgata gctttttcca aagtggtgac atccaacttt gttgattgtc
    36181 tgtcttcagc agtcacatgt tgtttttgtt tggcagatac aaaatggatt tgaccatctt
    36241 tcttggtaac ggtaatagta acgtcttcaa atccttttga ggatatcacg attgtatttt
    36301 ctccatcttt gaaagctttt gttccaagat gaagccctgt catattcgag acccagccat
    36361 tagtatcttt tacagaatct gaaataagat ctttataaac tgtaccattg actgtaacct
    36421 ttgtgatttg ctgagtcaat gcttttatct gtttgttatc agaataacga tcaatttctg
    36481 gaaataaaat tgcaccatct tcttgactca attttgttat taatgacaag ttagcagtat
    36541 ttttcccaga tttaacaact ttttgtgtgc cttggttttg tggcactgtt ttatcactga
    36601 gcacatcttt ttttaatgaa tcctgatgat ctgttgttcc taatttttga gctgaaataa
    36661 aggtcacttt atcgcccttt ttaataaagg taattaggat atcaccatct tttttattaa
    36721 caatagtcaa ttcatgctta ccgtctttaa taaggtcagc attgatctta atcccttggt
    36781 agttaatatc aaaggttcgc tcgccctcca ggcttttttc atagacatca ttatcaacaa
    36841 taatcttttc aatatgttta taatactctt ttccagctga ttgactagcg taagggccta
    36901 tctcttcaac taaaagtcga ttatcctgag ttaaagctac tgttgtcacg agttgtgact
    36961 gaactaaagg ctcttgtgat tttacagttt gagtagcctg aatgagaaca agggcagata
    37021 ttgccacaaa cgcacatttg ctgatttttt tcattttcaa tcaactttct aaaaatttta
    37081 tgaataagct aacttttata ttaactgaac ttaatctatc actttgtgat tattttgtca
    37141 agattgtttc caatggtcca attgtctgtt aaatagctcc actatgtgag ctaagacact
    37201 agtaataatc ctggattgat aatgaggata tctctgataa aagaattcct ctacaataat
    37261 attactgaga taaagctagc cttaggatag ttaatactag agctgattca atcattactt
    37321 cattcacaaa acatgtaaca cgttataagc tccataattg tgttaggaga caacatgaga
    37381 tgtcactact gcatattcat cacaataaaa aaagacaata gccctaatcg tgctattgtc
    37441 tcaaaatcat ttattgactt gaaactttat cgtgttacac caacagttta aaaggcctaa
    37501 ctcccgctaa gaaaattaag ccttaagaaa agtcattagt tattagtttt tactcttgcc
    37561 aataacatat gttagctgtt cagcctgctg agctgtaaag gtacgataag aaatcttacc
    37621 taagccgata cagttagact ctgaaataag aatagaccca tcttttctaa catcttctac
    37681 aattgatacg tggccataag tgccatcagc gcccgcttgc cctggtgcaa atgaaatagc
    37741 ataacctact tttggagtct ttgaaagggc ataccctact ttatacttcc aatctccacc
    37801 atttcccata aaaggatcaa attggtaacc caattctttg gcgcgattat acacatacca
    37861 agtgcattgt ccccaagcat aactcgaagc ttgataaccc aagacatcat aactcttaga
    37921 gagcttataa cctgctggca cagatgcaaa actagctgat gactgcactt tcaattcggc
    37981 tggaatggct ggtgtgccac catggtcatc aatccactta tccaggtctt ccataatttg
    38041 tgcgcgacgt ttaccactac cagtagtatc agtaaaataa acacccccgt cacttgcaaa
    38101 gtttaattga cctcgtgaaa acttagccgc ttttaaatct tgaagtgcaa aattgctatt
    38161 tttgttttta ataatggtgt cttgtgtcat tttgacaata gcactatcat cattaaactt
    38221 acttgcttga gtcggatcta gatcaaaagc tgcatagcca aacatattag ctccaagcaa
    38281 agttgcaatc ccttgagttc ctaaagaact ctcagacatc gcaatagcta cgatagctcg
    38341 aacatccagc ccacttttct tttcccattg caatagcttc tcaccattaa tacgtgtgct
    38401 gtcataggca atgcctgttg attttaagta actatcaatc tggtcagctt taataccata
    38461 acggcgagat aaaagatggt gggtataggc atttttacca ctccaatgct ctacatatgc
    38521 cgcgtatgtg ttgacagaag ggatatctat ctcactcaaa tctaaatctg atacgtaagg
    38581 ggacaacgac tgaataggag ttcttgcctc tggcagttgt ttcgacaatg aagaagcagg
    38641 tgccgtatca actttagatg gtgatggttt gggctggtca gttggtttcg aatgatcagt
    38701 tgatttcgaa tgatcagttg atttatcatc tacctggttt tctgcttctg ccttgttgtc
    38761 cgaagagcct atagcagact gactagaatc gcttcttttt ttatcatccg cgttaacaag
    38821 actattagag tttgtttctg cagaagcatc aaggggacct tggtcagttt tatctgatgt
    38881 tgtaggtgct gcatttttat tattttcctc ttttgaagaa gaatcactgg tttcatttgt
    38941 agttgcttta tgcgtctcaa gcattacatc ttgagccagc actgtcatgc tttctgctgt
    39001 cggggctaag agacttagta gcatggcaac tcttaatagt ttgtttttat tcatatatta
    39061 attagtcact tctttctaat gtcctcactt tattataaca ttaaagataa gcacaatgca
    39121 attattttta catgattttc ttaatatatc cgaggaatac ggtcacttaa aaggcataga
    39181 acttcataat tgattgtatt acggtaattt gcgatatctg ttgtagaaat atttttttgc
    39241 tgattgctgc caatcaaagt gacttttgtt cctaaaggat atgctttggg aagtcgtatg
    39301 gtcagttgat ccatcgatac acgccctata atttcgcaga attgtccatc aactaacacc
    39361 gaaaagcctt gcatgttcct ggtccagcca tctgcataac cgattgggac agtccctaca
    39421 tattcagact ttttggcagt ataagtagct ccataaccga ctgtatcacc agctgaaatc
    39481 atcttgacat gcactaagct agattctaga gataaagcct cttgcagtgg aaacggtaag
    39541 cttagatcag aaccacttgg attcaaacca taactgacaa ttcctaaacg aacagcatta
    39601 aaaatggtat cactatgcca gatacttgtg gctgaattac tagcatgtac taaacgaggc
    39661 ttatcctcaa gtccagctat cagcttttta aaaaactgta actgctggtt aaatttagta
    39721 tcatctgcct catcagctgt ggcaaaatga gtgaaaatac cttctacatc agcacccaac
    39781 tcttttagac tatcaatcaa taaattgact tcttttgaag aacgaagccc gatccgcccc
    39841 ataccagaat caacttttac atgaactttt aagccttgac attctttttt ctccagtcta
    39901 gctaaagcta tccagtctaa actagcgatt gtaacagtaa tagcattagc aactgctaac
    39961 tctaattcat ttggcagcaa aaccccaaga attaaaatct ctttatcaat acctgcttga
    40021 cgtaattgca aagcctcatc aagatttgac acacagtacc catccacttg aggtaggagt
    40081 gcttttgaca cctggacagc accatgacca taagcatcag ccttgacaac tgcatacgtt
    40141 tttaccccta gtggaatatg cttttgaaca ctggcaacat tctccttaat agcttgtaag
    40201 ttgacccttg caactgttgg gcgatggaaa cttgaaatca ttttttatcc tccaaaataa
    40261 cactagcctg tacataattg ccactatgtg agatgctaat aaaactattt cctttaaacg
    40321 gagattttgt cagaatggga catcctctaa catcatttaa aatctcaata tcttgaaagg
    40381 ttaaccgccc aatacctgtc cctatagcct tagcaaaagc ttccttacct gaccagcgtc
    40441 ctgccaaata gttgagtcga cgtttgtaag gaaaactctc aaaaatagcc aattcctgct
    40501 cagttaaaat tttttgagca aagcgaggat ttctttgata aactttttca atagctgaaa
    40561 tctcttgtaa gtctattcca tgtccaacaa tcattacttt ccaccaaacc ttatttcatc
    40621 ttaatgttag aagatttaaa cagtgagaag ctgagaatta ttctcagctt ctttctatat
    40681 acctaacttt gtcctgttgt gtctcgttct tatgagaagg atttacgacc gtgacaattt
    40741 ttgaattttt tgcctgaacc acatggacaa gcttcgttac gctccacttt gggtaaatca
    40801 tcggtgttag ctgactgctg cgattggatg ttttgaggtg ctgctgttgt ggcacgttga
    40861 cttgcacgtt cacgttcttg ttcgtgaatt tgtgctttca tcatggtacg tgttacatca
    40921 aactcgatag caccaatcat atcttggaac atcttgaaac cttctgcttg gtattccacc
    40981 acagggttat tttgagcata cccccgaagt ccaacagcat tacgaagttg atctaaggca
    41041 tcaatgtgtt cagtccattt gttatccaca atcatcaaaa tgagtacttt ttggaattca
    41101 ataatagctt cttgatcacg aagttttgat agttgctggt cgtagatagc aagcgctctt
    41161 tgataaagct tctctttgat ttgatcatct tttaaaccac gtaactcttt agcactaata
    41221 gactcttctg gtaccagcga ggtcctagca aaagttacaa tagcatctat agcatcttta
    41281 cgattgctac gtgcatgagc atctacagca cggtcgatag tacgcttgat catagcttta
    41341 atttctgggc caagatctcg attagcagtt atgacatcac gacggttagc atagataatt
    41401 tcacgctgtt cacgcatcac atcatcatat tgtaagacct gtttacgggt atcatagtta
    41461 tttccttcaa cccgtttttg agcagattcc acttgacgcc ctaacatacc tgatttaata
    41521 acagtgtctt cttcatctaa tttcatccga tccaaaaagg cttttatacg atcagagccg
    41581 aaacgtctca tcaaatcatc ttctaatgaa agatagaatt gggattcacc tggatctcct
    41641 tgacgacctg aacgtccacg aagctggtta tcgatacgac ggctttcatg acgctctgta
    41701 ccaatgacac ataacccacc aagttcacga acaccttcac caagcttgat atcagtacca
    41761 cgaccagcca tgttagttgc gattgtaaca gcaccacgtt gcccagcatt cataatgatt
    41821 tgagcttctt taaagtgatt tttagcattc aaaacctcat gaggaatccc tgcttcaacc
    41881 agcttgcgtg aaatcaaatc actagtttca acagcaaccg tacctacaag gataggttgt
    41941 ccttttgcat gacgcgtttt aacgtcttcc acaactgctc taaactttga ttctaaggtc
    42001 gggtaaagca aatcagtgtg atcaatacgg gcaattggac gattggttgg aattggaata
    42061 atacgcatgt tataaacttc gcgaaattct tcttcctcgg tcttcgcagt accagtcata
    42121 cctgccaatt ttttgtacat acgaaacata ttttggtaag tgattgaggc gctggttttt
    42181 gattcttcct gaatacgaac gccttctttt gcctcaatag cttggtgcaa gccgtctgag
    42241 aagcgacgcc cttccatcgt acgacctgta aattggtcaa caataagaat ctcaccatct
    42301 tcgctgacca cataatcgat atctaacaac ataatatagt ttgcacgaag ggcgttgtct
    42361 ataaagtgag tcaaggctac attttcaata tcgtaaagat tgctcaagtt aaagtaactc
    42421 tcagctttat caatacctga atcgcttaat ccaatcgttt tagtgggcac atcaataaca
    42481 taatccactg acgtcagagt ttttacaaac atgtcagcac gaatatacaa ttgattggtt
    42541 tcagagctaa cagcaccaga aacaattaaa ggtgtccttg cctcgtcaat taagactgag
    42601 tccacttcat caaccaaggc aaaattgagt gggcgttgta ccatgtcttc ctggcgaaca
    42661 accatgttgt cacgaaggta atcaaaaccg acttcagagt tggttgaata agtaatatca
    42721 caattataag cttcacgttt ttcagcagga gacttagcag ctaggttgat cccaactgaa
    42781 agacctaacc agctatacac ttcacccatt tcggtagcgt cacgcgttga aagatactca
    42841 ttaacagtaa taacgtgaac accctcacca gcaatagcat tgagataaac tggcatggtg
    42901 gctgtaagag tttttccttc accagtacgc atttcaggga catccccgtt atgaagaaca
    42961 attcctccca taatttgaac acgataaggg aacaagccca acacacgttt tgctgcttca
    43021 cgaacaactg cgaaagcttc aggtaatagt tgttcgaggg tctcaccttt ttgatagcgt
    43081 tctttaaatt caagtgtttt tccttgtaga tctctatccg acaatgacgc catttggtct
    43141 gcgtaggatt ctactttttt tgcaattttt tctaattttc ttagttcgcc tttgtcattt
    43201 tcgataactt tgcgtagaat attggccatt ctctttcctt tcgatcatct aatcatttca
    43261 ttttaacata aatatgcagg cagttcaaga aaggttggta aagtt
//
LOCUS       DAUGQX010000011        41464 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUGQX010000011 DAUGQX010000000
VERSION     DAUGQX010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41464
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.011"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            301..1074
                     /locus_tag="VIA51_000526"
     CDS             301..1074
                     /locus_tag="VIA51_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8682492.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
     gene            1735..2022
                     /locus_tag="VIA51_000527"
     CDS             1735..2022
                     /locus_tag="VIA51_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HEQ8682493.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            2012..2347
                     /locus_tag="VIA51_000528"
     CDS             2012..2347
                     /locus_tag="VIA51_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8682494.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKIIHYHSTKGYTLSKDYIVLYHIEGEENRIVIDYLLPT
                     QSDYIKLFK"
     gene            2499..2969
                     /locus_tag="VIA51_000529"
                     /pseudo
     CDS             2499..2969
                     /locus_tag="VIA51_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988074.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            3015..3452
                     /locus_tag="VIA51_000530"
     CDS             3015..3452
                     /locus_tag="VIA51_000530"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8682495.1"
                     /translation="MEKSTKNDFSVRKIKLDSETISILQEWKAISQKEKTQLAVAPLS
                     IKSDFIFTYCTREGSIEPLHADYINNILSKVIKQHSLKKISPHSFRHTHATLMIEIGV
                     DPVNTAKRLGHASSQMTLDTYSHATAVGEDKSIKQFANCLKNN"
     gene            complement(3572..3964)
                     /gene="rpsI"
                     /locus_tag="VIA51_000531"
     CDS             complement(3572..3964)
                     /gene="rpsI"
                     /locus_tag="VIA51_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEQ8682496.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3985..4431)
                     /gene="rplM"
                     /locus_tag="VIA51_000532"
     CDS             complement(3985..4431)
                     /gene="rplM"
                     /locus_tag="VIA51_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEQ8682497.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(4649..4855)
                     /locus_tag="VIA51_000533"
     CDS             complement(4649..4855)
                     /locus_tag="VIA51_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682498.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(4852..5358)
                     /locus_tag="VIA51_000534"
     CDS             complement(4852..5358)
                     /locus_tag="VIA51_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682499.1"
                     /translation="MFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGG
                     VAFVLTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLSMGASIFYRHY
                     LDAKEADE"
     gene            complement(5494..6354)
                     /locus_tag="VIA51_000535"
     CDS             complement(5494..6354)
                     /locus_tag="VIA51_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8682500.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(6451..6969)
                     /locus_tag="VIA51_000536"
     CDS             complement(6451..6969)
                     /locus_tag="VIA51_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEQ8682501.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            complement(6973..7719)
                     /gene="rlmB"
                     /locus_tag="VIA51_000537"
     CDS             complement(6973..7719)
                     /gene="rlmB"
                     /locus_tag="VIA51_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEQ8682502.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(7766..8563)
                     /locus_tag="VIA51_000538"
     CDS             complement(7766..8563)
                     /locus_tag="VIA51_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682503.1"
                     /translation="MTTMQKTISLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAM
                     TNSVDVDTKAQTNQSANQEIDSTSNPFRSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLLGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(8759..9172)
                     /locus_tag="VIA51_000539"
     CDS             complement(8759..9172)
                     /locus_tag="VIA51_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEQ8682504.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(9165..10508)
                     /locus_tag="VIA51_000540"
     CDS             complement(9165..10508)
                     /locus_tag="VIA51_000540"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEQ8682505.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNIYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKTIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAVQGIKLLDTKDGVRWLRD"
     gene            complement(10536..10766)
                     /locus_tag="VIA51_000541"
     CDS             complement(10536..10766)
                     /locus_tag="VIA51_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682506.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(11245..11826)
                     /gene="cysE"
                     /locus_tag="VIA51_000542"
     CDS             complement(11245..11826)
                     /gene="cysE"
                     /locus_tag="VIA51_000542"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEQ8682507.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTVRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(11835..12587)
                     /locus_tag="VIA51_000543"
     CDS             complement(11835..12587)
                     /locus_tag="VIA51_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEQ8682508.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLIFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(12580..14712)
                     /gene="pnp"
                     /locus_tag="VIA51_000544"
     CDS             complement(12580..14712)
                     /gene="pnp"
                     /locus_tag="VIA51_000544"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEQ8682509.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGDSTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDVDLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAIDRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            complement(14993..15724)
                     /locus_tag="VIA51_000545"
     CDS             complement(14993..15724)
                     /locus_tag="VIA51_000545"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEQ8682510.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTARVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDYNH"
     gene            complement(15734..17112)
                     /locus_tag="VIA51_000546"
                     /pseudo
     CDS             complement(15734..17112)
                     /locus_tag="VIA51_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            complement(17139..17423)
                     /locus_tag="VIA51_000547"
     CDS             complement(17139..17423)
                     /locus_tag="VIA51_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8682511.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            complement(17416..19476)
                     /locus_tag="VIA51_000548"
     CDS             complement(17416..19476)
                     /locus_tag="VIA51_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8682512.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKASKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQKKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKSVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(19828..20097)
                     /gene="rpsO"
                     /locus_tag="VIA51_000549"
     CDS             complement(19828..20097)
                     /gene="rpsO"
                     /locus_tag="VIA51_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEQ8682513.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     QHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(20255..20410)
                     /locus_tag="VIA51_000550"
     CDS             complement(20255..20410)
                     /locus_tag="VIA51_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682514.1"
                     /translation="MTMLGYRLSAEVRGSAILPLLAGYLIRQAIAQVYSDLKTASWLF
                     GLASSVA"
     gene            20536..20805
                     /locus_tag="VIA51_000551"
     CDS             20536..20805
                     /locus_tag="VIA51_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8682515.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTYRIADLDALTQLRPLRYAAH"
     gene            20906..21520
                     /locus_tag="VIA51_000552"
     CDS             20906..21520
                     /locus_tag="VIA51_000552"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8682516.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(21554..22096)
                     /locus_tag="VIA51_000553"
     CDS             complement(21554..22096)
                     /locus_tag="VIA51_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8682517.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(22227..22655)
                     /locus_tag="VIA51_000554"
     CDS             complement(22227..22655)
                     /locus_tag="VIA51_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8682518.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(22765..27162)
                     /locus_tag="VIA51_000555"
     CDS             complement(22765..27162)
                     /locus_tag="VIA51_000555"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEQ8682519.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYEPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            complement(27417..29273)
                     /locus_tag="VIA51_000556"
     CDS             complement(27417..29273)
                     /locus_tag="VIA51_000556"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEQ8682520.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSIASMDDIPKEVLEDIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHMTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            complement(29471..30730)
                     /gene="rseP"
                     /locus_tag="VIA51_000557"
     CDS             complement(29471..30730)
                     /gene="rseP"
                     /locus_tag="VIA51_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEQ8682521.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPTSLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSRAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(30803..31597)
                     /locus_tag="VIA51_000558"
     CDS             complement(30803..31597)
                     /locus_tag="VIA51_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEQ8682522.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(31610..32359)
                     /locus_tag="VIA51_000559"
     CDS             complement(31610..32359)
                     /locus_tag="VIA51_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEQ8682523.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            complement(32578..32943)
                     /gene="yajC"
                     /locus_tag="VIA51_000560"
     CDS             complement(32578..32943)
                     /gene="yajC"
                     /locus_tag="VIA51_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEQ8682524.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELLAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(33059..33433)
                     /locus_tag="VIA51_000561"
     CDS             complement(33059..33433)
                     /locus_tag="VIA51_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEQ8682525.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            complement(33548..37045)
                     /locus_tag="VIA51_000562"
     CDS             complement(33548..37045)
                     /locus_tag="VIA51_000562"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEQ8682526.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGLQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGHYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDRDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPGNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKAS
                     DDKVPNKATLIDAVAQYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLVDAEQAGVTAIAKPKGVQFTKEGLTIEGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGIALLLLAISLLMKRQKD"
     gene            complement(37243..38856)
                     /locus_tag="VIA51_000563"
     CDS             complement(37243..38856)
                     /locus_tag="VIA51_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEQ8682527.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDYYIWRDEPNNLMSIFSGSAWELDEASGQYYLHLFSK
                     KQPDLNWENAQLRQKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFATDLAGAQ
                     VIIANTDVDTVLETKHLQPWDAFCLKLKA"
     gene            complement(38985..40118)
                     /gene="ugpC"
                     /locus_tag="VIA51_000564"
     CDS             complement(38985..40118)
                     /gene="ugpC"
                     /locus_tag="VIA51_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEQ8682528.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLDIAIPEG
                     QAKMLEAAGYKGEKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(40416..41264)
                     /locus_tag="VIA51_000565"
     CDS             complement(40416..41264)
                     /locus_tag="VIA51_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEQ8682529.1"
                     /translation="MELKDYFPEMQVGPHPLGDKDWMSIKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLYETSQFIYLNHQQALPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
BASE COUNT        12287 a         9089 c         7747 g        12341 t
ORIGIN      
        1 ttgttttatt tttataaaaa ataaacaaaa tatgtttatt tttttcattt ttacgttatt
       61 atcctaatgt ttcttgtgtt tctttttcat ttcataaatc cctttaacag ccactcgtaa
      121 cctatcatat attacgaaac ccttatctct atttattgta aacgttttat ttaaaacatt
      181 ttctattttg ttaatttttg ttttttctaa tgtttatgtt tgttttgttt gattttttta
      241 ttgatattat gttatgatac ctttaatagt tataccctaa gacactgata ggagataaga
      301 atgaaaaaga aagagcgtca tgaaaaaatt ctcgatatct taaaagttga cggttttata
      361 aaagtaaaag atattatcga tgaaatgaac atctcagata tgaccgctag acgagatctc
      421 gatacattgg cagataaagg attacttatc aggacccatg gtggtgctca atatttggat
      481 tattcttcag caaaggacga aggtcacgag aaaacacaca ctgaaaagaa ggtcttacag
      541 actaccgaaa aaaaacaaat tgcacaaaga gctaaaaaca ttattaaaga tggcgaaact
      601 gtctttatag gtccagggac aacattagag catctagctg tcgaattgaa aaatagaaat
      661 atcagagtta ttacaaatag ccttcctgtt tttttaattt tgcacccgag cactactatt
      721 gatttgattt taattggtgg tgaatgtcgt gaaattactg gtgcttttgt tggtgctatt
      781 gccattaata acctagaaac attaacattt tcaaaagctt ttgtcagcgc aaacgcagtt
      841 tacaataatt ctattgcgac gtacagtgat ctcgaaggag aagttcaaag ggttgcattg
      901 aataatgctg ttgagaaaat ccttctagtt gatagtacca agtttgaaag ttatgacttc
      961 tataattttt accaactaga tcaagtggac ttaattgtga ctgataaaaa tgtgacaact
     1021 gatatcatag aaaagtacaa gaaattctca aaaatcataa tcgctgacaa gtaaaggacc
     1081 tactcatatt aaaaagcact tcagggttta gatatatccc ctgtcaagta aacagggagc
     1141 atatctgaaa gtagtgtttg tgttataaag aagtttcttg ctaacttatt ttctgttttt
     1201 tttcagactt atcagtcttg tactgttcct ttttctgatg aataacgtgg aaataggcag
     1261 acagctatat atttcacctc tagaatggtt gccattactg tcatcaagac atgcttgttc
     1321 tttatcgtat ggagtaaagc tttcttttag ccatcaacat acctcttaag tagattttgg
     1381 ttcgttacca tgtctactta agaggtgtct tcaaagcgct ttaaaacgtt gctataacag
     1441 tatattaacg ttttgagaat tgtgaagctt tacgagcttt tttaagacct ggtttttggt
     1501 tgatattctg atatacataa agatacttat aaaatcaacc tattcctggt tcaatcaatc
     1561 aaaatctatt aattatatac aaatatctta ttcccaacgg tatcaataag gtatcaaaaa
     1621 taagtttcgg agcttatcaa ataatgaaaa tctgtctcaa ttaccgagtc ttttttattg
     1681 acttttttgt atatatgata taattaaata agttacataa aggggttaca taaaatgact
     1741 acagtaaaaa aaaacagagc ggttaccttt caagctaata aagaattggt aagcgaagca
     1801 atgacagtat taaacaaaaa aaatttaacc ttatcatctg ctttaagatt attcctacaa
     1861 aatgtcgttg tcacaaacga ggttgactta ttgacggaag aggagttaga gaaagaaaaa
     1921 cttttcaagc aatttcaagc tgaaatcaac aaaaatattg aggatgttcg tcaagggaag
     1981 ttttatacct ctgaggaagt gagggctgaa cttggactat aagaaatatc agattatcta
     2041 tgctcctgat gttttagaga agctaaaaga aattcgtgat tatatttctc aaaactattc
     2101 ctcaacatca ggtcagcgta aaatggagca aatcattagc gacatagaaa aactcgaggt
     2161 tttcccagaa gttggttttg atgccgatga aaaatatggt tcaaaaatca tccattatca
     2221 cagcactaaa ggttatacct taagtaaaga ttatattgtc ctataccata tcgaggggga
     2281 agaaaatagg atcgttattg attacttgct tcctactcaa agcgactata taaagttatt
     2341 caaataacac gttaaaagcc ttagcagtct tgctagggct tttttggtag attaccaatt
     2401 aactaggagc aaaatgagtt cgggctgttt agtagatatt ccacaaagaa gccaaagact
     2461 acgaagctag gctaatctac cttaaggctt caggaaactt ggaggagttc accaagccaa
     2521 ctcataaaac ttatagcgag atattcgaga aatggtatca agcctatcaa gatacggtag
     2581 agccaaccac ggcttctcgt actcttgatc tgtttcgact tcacattctg ccagtcatgg
     2641 gagaattgcc cattaacaaa acctcccctt tagactgcta gaacttcatc accgataaag
     2701 caaagacctt taagaatatc aagcaaatca agtcctacac tgaaaaggtc tttgattttg
     2761 ccatcaagat gaaactgctc aagcataacc ctatggctga aatcattatg ccaaagcgga
     2821 aaaagacacg aatagaaaac tattggacgg ttcaagaact tcaggagttt ttagccatag
     2881 tacttcagaa agagccttac aagcactacg cactatttcg gctactagct tatagcggca
     2941 gctatgcgct cttaaatggg ctaatataga cactaagcgt caataagagc ctaggacgat
     3001 tagacggaca ggcaatcgaa aaaagcacta aaaatgattt ctcagtaaga aagattaagc
     3061 tagacagcga aactatttct attctgcaag aatggaaagc catcagccaa aaagaaaaga
     3121 cacaactagc agttgcacct ctttcaatta agtctgactt tatatttaca tactgtacta
     3181 gagaagggag tattgaacca cttcatgcag actatattaa caatatctta tcaaaggtca
     3241 ttaagcaaca tagtcttaaa aaaataagtc ctcacagctt caggcatacc catgcaaccc
     3301 tgatgattga gattggagtt gacccagtaa atacagccaa aaggttagga catgctagta
     3361 gtcaaatgac tcttgataca tacagtcatg ctactgcagt cggagaagac aaatcaatca
     3421 aacaatttgc taactgtctc aaaaataact aaataaacgt attaaaccaa gtcaaaagtt
     3481 ttccgaaacg gtatcaaaag caaaaaacga caaaaaaagc accttgcaag agacttgcaa
     3541 aatgcttgta atcgttgatg taaagctgtt cttaacgttt tgagaattgt gaagctttac
     3601 gagctttctt aagacctggt tttttacgtt caaccatacg tgcgtcacgt gtaagaaggc
     3661 cagcgcgttt caatgaatcg cggaagtctg ggtctacttg aagaagcgca cgagcgatac
     3721 catgacggat cgcacctgat tgtccaccgt aaccaccacc aacaacgtta acgaaaacgt
     3781 cgtatgaacc ttcagttgat gtaactgcaa aaggttggtt gatgatcaaa cgtaagtcag
     3841 catgtgggat gtattcttct acatcttttt tgttaacagt gattttacca gtacctggaa
     3901 ccaaacgaac gcgtgcaaca gcgtttttac gacggccagt acctgcatat tgtgcttgtg
     3961 ccattattta atgctccttt cctcttagat aagtcctgag atgtcaagta cttctggttg
     4021 ttgtgctgcg tgagtatgct caccgccaac gaagactttc aatttcatac cttgtgcacg
     4081 tccaagagtg ttatgtggaa gcatgccttt aactgatttt tcaatcaagc gaactgcgtt
     4141 tttagagcga agttcaccag cagtgattga tttcaaacca cctgggtaca ttgagtgagt
     4201 gtagtaaact ttatcagttg cttttttacc agttaattta actttttcag cgttgataac
     4261 gataacaaaa tcacctgtat cagtatgtgg tgtgaaagtt ggtttgtttt ttccgcgaag
     4321 tacgctagca actactgcag aaagacgtcc aagtggcaca tcagttgcgt caacaacgta
     4381 ccatttgcgt tcaacttggc ctggtttagc catgaaagtt gttttgttca tgatttctcc
     4441 tatacgaatt cgtaatattt gtttacaagg tgatgggtgt tccgtcccat cgaaggtatt
     4501 tggaaggttc cggggccttt caaatggggt aaacaatacc gcctactatg atatcaaact
     4561 taagaggctc cagtcaagtg ctttagctga ttttattgga ttattttttc tttcgattta
     4621 ggagaatggc agagctgctc tgctggtgtt aacgagaatc atcagcttcc caaaaaaggt
     4681 catctaaagt cttatcaagc actcgacaaa tggcaatgca aagattaatc gttgggttgt
     4741 aatcaccttt ttcaacagcc gcaatggttt gtctggagac gcctaccaaa tctgctagag
     4801 cttgttgaga caaatctttg cctgcacgcg ctgcttttaa tttgaggttc ttcattcatc
     4861 tgcctcttta gcatccagat aatgacgata gaaaatacta gctcccatac taaggttaca
     4921 atatgtcgtt tgaactgcca accctcccca aagagccaat gtaaagagga agcttgcaga
     4981 taccagtccc tctgtgaatc ggctaataaa gagtgacagc cagataacca caatcataaa
     5041 ccaaaaccca atagtgtatc ctttgagaag aatctgtttt tggcgttcat catatttggg
     5101 caacttctga tcgtccctta ccttagaatc tagtacttcc ttgctgtcta gtctcgtttg
     5161 gagctttttc gctgtcttta gcccccatac caacaatatg agaaagctag tcaatacaaa
     5221 agctacgcct ccaactaagt aacgttgaaa actggtctta gccagtaatg ttgctactat
     5281 cacaactaga tccatcactg ctgttatgac aatgaaaccc cattgtgact tagcgagatt
     5341 ttgtttgcta tcaaacatga ttcgtttctc ctttaaatct ttatatgaca taatataaat
     5401 tattttggat attttgtcaa atatatttta cataattgat tgacttaagc agcaaaaaag
     5461 gattgaggat ttctcttcaa tccttataag ggattaacgg gaattctgcc caatcacaaa
     5521 aactgccagg gtgttaggac caacgtgagc tgagataact ggtcctagtg gcatcataag
     5581 aacatcgcta atattctcat gcgccagcag ctcttctcgt aacttttcgg cactaccctg
     5641 atcgcttgta taagagacaa taaccgtcga atccgcaata tctttttcca cttgagccac
     5701 catttctttg atggcttttt ggcgtccccg aatttttgca atgggcacca atttcccttc
     5761 ctcatcaatc cacaaaagag gtttgatact ggctaaactg cctagaaaag ctgaaccttt
     5821 tgacagacgc ccaccacgca tcaaatgaaa aagatcatct actaagaaat aggtgcgcag
     5881 tcgagggatc actgcttcaa caatatcttt agtctccagt aaatttttgc cactatctct
     5941 ggcttctgct gctaaaatgg ttagatagcc ttctcctcct gcagcagcca aggtatcaac
     6001 aatttcaatc accgcatcgg gataatcttc tcgaacaaga tcgcgtgcca ttagagcgct
     6061 ttgataggta cccgataaaa ccgaagaaaa agcaagataa agcagtgctt tgttgttcct
     6121 agcatgttca cgaaaaacct tctcaaactc tcccacatta atctgactgg tttgaggatg
     6181 actgccagct ttcatctttt tcaaaaggta atcactacta atacggttag gaccgaccgt
     6241 ttcataaacc tctccatcgc acaaaatcgt taatcctata aggacaatat catgatcttc
     6301 tgcccaggtt tgattcaaat cagcggttga atctgtcatt attgtaaagg tcattcttac
     6361 ttctcctcat ccagtttttt agtttgataa tcaaataatt attgttttat tttatcaaaa
     6421 aaacccgcac ttggcgagtc gtaattctca ttatcgatct aactgagaca taaaatcctt
     6481 caattgaata agctgtcctt ggtcaaaagg ccgcagttta ggcgttttga gatcaatatc
     6541 tctagacatt ttatctaaat cagctttgac agtatgaact ctttgctcta attctcttgc
     6601 agtgacacga agagctcctt gagaaaaaat cgtccattgt tcatttaaat cactcgtagc
     6661 tacttctacc atatgtatag ccgtatttaa ctctgctgcc atgcgctcaa tgtagctatc
     6721 tgctgtttcg tcttcctctg taaataccac tgagatataa tactggtcat atcgttgcct
     6781 taaccccggt acatattggg catcaaaaac acaaataata ttaatattct caaaatgggc
     6841 ataatgatta agttttgtta aaagtgtgtt acgtgcctga tcaagctgat ttgtcttaaa
     6901 caactgacgg gttgattgcc aaaaggcaat catattatac ccatctacta ataatatccg
     6961 ttttttcata atttagcgcc tatttcggaa aacttcatac atgagaatag ctgccgctac
     7021 gctagcattt aagctctgta cgtgaccatt cataggaatc gtaatcattt catcaacttg
     7081 ctttttgata ttggtagaga tgcctttacc ttcgttacca atgactaaag caagtttacc
     7141 attagtgttc cagcaatcag acggtgttcc attcatgtct gtgccaaaaa tccagaatcc
     7201 tcttgctttc aatttatcta gagtttgact aaggttagtt actctcgcta tcggaatatg
     7261 ttcaacagca cctgtagacg tctttgaaac cactggagtc acaccaacag aacgatgttt
     7321 aggaataatc actccacata catttgtagc atcagctgtc cgtaaaatcg atcctaaatt
     7381 atgaggatct gtcagaccat ctaaaataag aatcaaagga tttgcttctt gctctgctat
     7441 ttcgaggatc tcatcaacat cagtataggc aaaagctgat actctcagaa caaaaccttg
     7501 atgcacagct ccatcagtca tttgtgacaa ggttttttta ggcgtccatg aaatagcgac
     7561 ctttttttgt gtcgctaagc ttttgatgtt atccactttc tttcctctta aatcctcttg
     7621 gatataaagc ttatttcctg tatttgcttg aaggctttct gtaacggcat gaacaccata
     7681 gacgatatcg tttgtttcaa tagtatcttt atcttccatg agtttattat accatgaatg
     7741 cttcaaaata aatgcataga ctcttttatt ttcgtctaga tactttttga atagctataa
     7801 ataaacctgc agctaaactg actactagac ctaataagac ccaagggaat cctctttttg
     7861 aagtaggttt tacttcctct ttgtccacta gcatttttgt cttgttgcta ccgttttttt
     7921 ggctattact agcagttggt gtaagtttct catttttagt agatcgcttt aaggaagttg
     7981 atcgatgatt agtagctgat ctgaaaggat ttgaagtaga atctatttct tggttagctg
     8041 attgatttgt ttgagctttt gtgtctacat cgactgaatt cgtcattgct ttagaagtat
     8101 ccttttgttg catattagtt ggtgtttttc tagctttgtt ttgatcaaaa tgaacagttc
     8161 ctgattgacc agttactgcc ttttcttgag tatgaacggt gacagttaca tgatagtcac
     8221 cactcttttg tccagttaaa tcaaaccaag ctgtaaaacg acgctgttgc gctgccatag
     8281 tatataccca actattaata gtattatcac tagcgtcttt aagtgttatc gttgcctgag
     8341 ttggttgtct gacaggttga tctgtggtga ctgtagcatc aatataaggt tctgttccac
     8401 gcatactggc ttcaacactg acctgactaa tagttgattc agctataaca ttatcagtgt
     8461 gctgatcttg tgcatacaca gatatggctt tgccagaagt ccccagcaaa ccaataagta
     8521 aagctagtga taataagcta attgtttttt gcatagttgt cataataaat atctcctctt
     8581 taaattaatc ttaccctctc attataaact attcgaaaat gatttcatta tttttatgtc
     8641 ttttttgtta caaatgtatc ttttttatat cattatgtct ttttgatgtc ataaaaagac
     8701 ttaatggctc tctaccttta cttcagacct atgaaaataa gagtctccta ggggactctt
     8761 atgaggatat caattgttgc ttttctacat actcaataca ccatctgatc aattcttcta
     8821 accgctcttt ttggcccatc atatcaagat aacccataat ggcttcaaaa cctgtcgaca
     8881 tacgataggt aataatatcg gcattcttag ctttagtatg gctattggta ttgcgaccac
     8941 gcttatagat gtcttcttct ttttcggtca atagctgcgc ttctaacata gcctgaatca
     9001 agttggcttg tgccttagca gaaacatatc tcgttgctaa acggtgtagc tggctaggtt
     9061 tcgttttacc ttgaaaaatg agatgacgac gaacatagta ggaataaacc gcatcccctt
     9121 caaaggctag ggcaatgcca ttaatcaaat tcacatcaac tggattagtc acgcagccac
     9181 ctcacaccat ctttggtatc tagcagcttg atgccttgaa ctgctaactg atctcgaatg
     9241 gcatcagctg tggcaaaatc acgattcgcg cgtgcttctt gtcgcttggc aatcaaggct
     9301 tcaatgtcaa cctcaagcac ctcttcttca aagataatgc caaaaacagc taacattttc
     9361 tcaaaagcgc ttttaacagg ttctgtatag gagccagaat taatccactt ggccatgtca
     9421 aatacgacgg taatcccatt tgctgtattg aaatcatcgt ccatagcgtc ttggaaagct
     9481 attacaaact gttttagctc ttgctcatct gcagtttctg tcagcggttg ttgcaaggtg
     9541 tttttaagat acttcagatt gatttccgca tcatgaatag tcttttcagt gaagttaatt
     9601 ggttttcggt actgttgtgt cgcaagaaag aatcgcaaaa cctgaccatc aacggtttgt
     9661 aacatgtcat gaacggtcac aaaattacct agtgacttgg acattttttc gttatcaaca
     9721 gtgacaaacc cattgtgcat ccaatagtta gcaaaagtct tgcctgtttt ggcctcagat
     9781 tgggcaattt cattggtatg atgaggaaat tccaaatcag ctccgccacc atgaatatca
     9841 atggtatcac caagaatttc agtagccatc acagaacatt caatgtgcca gcctggacga
     9901 ccaaaccccc aggggctatc ccaagaaacc tcacctgcct tagctgattt ccaaagagca
     9961 aagtccagtg gattttcttt taaagctgtc tcagcatctg ttcgaccact ggctccaact
    10021 tcaagttctg acagggtttt attagctagc ttggcataat gctctgactt ttccacgcgg
    10081 aaatacacat ctccatctgc ttcgtaagca aaatcttttt caatgagact ttcaacaaat
    10141 gaaatgattt ctgctatata atccataaca cgaggatttt gtgtggctgg cttaacacca
    10201 agtgccttgg tatcttctat aaaagctgca ataaagcgat ctgacaattc tttaggagaa
    10261 acacctgctt gagtagcagc cttgataatt ttatcatcga catcggtaaa attggaaatg
    10321 taattgacct gatagccagt atactcaaaa taacgtcgaa tggtgtcaaa agcgaccgct
    10381 gatctagcat ttccaatatg aatataatta tagaccgtcg gtccacaaac gtatatattg
    10441 actgtatttt cagtcaaagg tacaaacttg cggagcgaac gggtcatggt atcataaatt
    10501 ttaatcatgt aaactcctta ttcaatagtc tggcattagt tgtcatcttg atatcctaag
    10561 tctttttctg aaatgctgtt ccaccttttc aacaatttaa tattaataac caaacctatt
    10621 aaccaaaata gggtcaaaat gaagtatata atcgctttaa ccatgtcttg tctcagtaaa
    10681 aagattagac tagccaccag tgtaatacta gaaacaagaa tagacaaact cataatgaca
    10741 tacagcccaa ctcttatttt attcatgagg ctcctttatt aacgaaaaac cttcacaacc
    10801 tgtgaaggct tcagaaagta gacaaaccca cttttatgct caaaaagcat gaatagatct
    10861 gctgatttga catcaggttt cctatttctg catgtggggt gagccaaaac agctgctttt
    10921 tgttgtggta aaagtggtat caatactgac agtgatgccc atacagattt ttgagacctt
    10981 aggctcaaaa ctaaggcatg gaattccaaa ggaagtcgct gccgtaagca ccacctgaga
    11041 aaaagtatca caatagactg tttcttcagt ctaagacttg cttagttgat gctcttttac
    11101 gtgttttttg tattttgtaa cattcccata tcactacact cagcaaccaa actgataggg
    11161 ctagctaagt tcaacattac tctactagaa agtcccaaaa tattttatcg gaagtcatca
    11221 gtgcttcttt ttgttatttt ccgatcattt tgacaactga taagagacct ctcgttgttt
    11281 ttgtaaactt tgaatttgac gattatcttt ttgcccatgc actcgtacta tcttagctgg
    11341 cacacctaca actgtcacgt cttcaggaac atctgataac acaacagctg ctgcccctac
    11401 tttagcattt gctccgatgt caataggtcc aatcacttgg gcatgtgccg aaattaaggc
    11461 accttgtcga accgttggat gacgcttgcc acaatctttt ccggttccac ctagggtcac
    11521 cccatgataa agcatcacac ctttttcaac aattgctgtc tctccaataa caagaccagc
    11581 accatggtca atgaagactc caggagcgat ttgtgctcca ggatggattt caatttgtgt
    11641 ccaaaatcgc caaaattggc tatgcattct ggctagtaat ttaaaatgat gtcgccaaag
    11701 aaaatgagac aaacgatgag cagctagggc tttgatgcct ggataagtta ggataacctc
    11761 aagactatta cgagcagctg ggtctagagc tttaacaata gctatacttt ctttccacca
    11821 acccatacta actcctacga cttatctaat tctgaccaat caacaagaat ttgttggtca
    11881 tcaaaaggat tgatggcgac accgaacgtt tcatcaagct cgttttcacc atttcttggt
    11941 tgataaatat catcaatcgt ccaagtcaga atcactcctt cagctttcct gaaaaggcct
    12001 ccaaaatcgt cttggttgta ccatttcgca aagctttgaa gatttgaaaa ggcgggaaca
    12061 tagctttttc cttcaggcgt tgacatggta ggaaaaaggc ggtcgtaatg gttattatct
    12121 ttaggataaa caaaggcagg aacaaggtaa accttttcca tcgtatctgc cgccacattg
    12181 tcatcactca taagcgtatt taacacagtg gtgtaatggt tcataaattg aatcatatca
    12241 ctgcttttga aaatggtaga attcccaaaa tctccctttt tcttaaggtt aaagataaga
    12301 cctgctgcac cagatgtaat gacttcttct agcactgcaa gagctgaacg ctccagccaa
    12361 tactgacttt gagcactctt ttgttcttct ttaaagcgag ccatatcttc cttatcggta
    12421 aaaacagggg taaccttgac accttcgact tctatcacgt agggttcttt agcagcccag
    12481 acaggaaaat tatggaaagc gttgacaagc gcaaggctat ccaaaaagtt atcaggcgca
    12541 ttgataaaag ctcttaagcg aatatctaat tcatttgatt tagtcatgtt tttcttcttt
    12601 tttctctggt tttggtgggc gtggaatcaa agctttcatt gaggcatcca cacgaccctt
    12661 ctcatcaatc ttaatgacct taacatcaac gtcttcaccc acttcaagga catctgacac
    12721 gttggtcgtt ctcgtccagg caatttcaga aatgtgaaca agagcatctg tcttgtcaaa
    12781 gaggttgaca aaggcaccaa atttctcaat acggacaacc ttagcatggt aaacttcgcc
    12841 taccttagct tcacgaacaa gacctgcaat aatttcttta gtgcggtcaa tggcagcttg
    12901 gtcacttgag tagatagaga catttccttc gtcatcaata tcaattttga cacccgtttc
    12961 ggcaataatc ttgtcaatag tttcgccacc tttaccgata accactttga ttttgtctac
    13021 gtcaatcttg atggtgtcaa ttttcggtgc agttggggct aactcaggac gtggttcagc
    13081 gatagttgct tcaatcacat caaggatttc aaagcgagct tttttagctt gtgcaagagc
    13141 ttcttctagg atttgagggg taattcctgc aatcttaata tccatttgaa gggctgtaat
    13201 cccttcacga gttcctgcca ctttaaagtc catatctcca aagtggtctt caagaccttg
    13261 gatatcggtc aagactgtat aattcgtccc atcggaaatg agacccatgg caatccctgc
    13321 cacaggcgct ttaatcggca caccaccagc cattagggca agggtcccag cacagataga
    13381 agcctgagaa gacgaaccgt tagattctag aacttcggca actaaacgaa tagcataagg
    13441 aaactcttct aagcttggca agacttgttc aagagcgcgt tcacctaagg caccgtgtcc
    13501 aatttcacga cgaccagcag ctccgtaacg acccgtttca ccaactgaat attgcgggaa
    13561 attgtagtga tgcaaaaagc gttttttgta ctctggggcc agaccatcaa tgatttgagt
    13621 ttctcccatt ggtgccaaag tcaaaactga caaggcctgc gtttgaccgc gcgtaaaaag
    13681 acctgatcca tgtacttttg gcaagaagtc aaccacagca tcaagcggac gaatttcgtc
    13741 aatcttacga ccatcaggac gaatcttgtc ttctgtaatg aggcggcgca cctcagcatg
    13801 ctccatttgt tcaaggattt ctgccacgtc acgcataatg gttgctaggt tttcgtcttc
    13861 tgcgtaacgc tcttcgtatt cagccttaac catttcttta acggcttctg tggctgcttc
    13921 acgcgctttt ttctcttcaa cttgaacagc tttttgcagt tgagcattgt acttagccac
    13981 aatatcagct tgtaagtcta catcaacctg taacagttca acctcagctt tttctttacc
    14041 aacaactgct acgatttgtt cttggaaggc aattaattct tgaatagctt ggtgaccttt
    14101 taaaagagcc tcaagcatga tgtcttctga taattctttg gcaccagact caaccatatt
    14161 gatggcttct ttgctaccag caacagttaa ttctaagagt gatgcttcca tctgttcttt
    14221 atctgggtta atgatgaact cgccatcaat atagccaact tgaacacctg caatcggtcc
    14281 attaaatgga atatctgaga ttgacaaggc cagagatgag ccaaacatcg ctgccattgg
    14341 agcgctagca ttttcatcat aagaaaggac agtgttaatc acttgtactt cgttacgaaa
    14401 accttcggca aacatgggac gaatcgggcg gtcaatcaag cgagctgtca aggtcgcatc
    14461 tgttgaaggg cgtccctcac gtttcatgaa acctcctggg aatttaccag cggcatacat
    14521 tttttcttcg taattaactt gaagggggaa gaaatcaccc gttgccattt tcttagacat
    14581 aacagctgcg gtcaggacag ttgagtcgcc ataacgaaca acggttgccc cattggcttg
    14641 cttagcgact tgaccaactt caacaacaag gggtttccct gcaaatgttg ttgtaaaggt
    14701 ttgttttgac atatattctc cttttaattt tcagaggggt aaagaggtac ctgttctctg
    14761 cttagattca gttgttatac gttgttttgc tacaaaaagc aacctgccac gcttgtcaca
    14821 cgctcctctt tgtatcaaac gacgtatctg ctacatttta ccataaaata ctagaaattt
    14881 cactgtcaga tcgcaatctc ttgaaatgtc cttgaaaaat attaaacgaa acttatactc
    14941 tttaacaaag caaaaaaaag caggttggta tgcctgcttt cgtctcctaa tattaatgat
    15001 tgtaatcctc taaaatttta aagccgaggc tggtactgtc tttcagaaac atttgcacgg
    15061 tttcaaggga atagtcttct aaatcttttc cttgaagagg caacttggca atcaaatcag
    15121 tggtacaagt gataatgtcc acgcctagct gatcagcttg atagatatta taagtttcac
    15181 gaggactagc ccacaacaat tcgacccctt ctttttgacg acaaatgcgt agagcttctt
    15241 ccatgattgg cattgggtca acgccggtat ctgcaatacg accagcaaaa acagacacaa
    15301 tagctggaac tcgagcggtt aaatgatcaa ccacagcttg agtctgctca attgtaaaaa
    15361 tggctgtgac gtttaactta atgcctttgg ctgacaactt ttgaatgagg ggacaggttg
    15421 attctcctgt tgaagtggtg actggaattt tcacatagac attgtcacct agactggcaa
    15481 ttttctcagc ttccttttcc atgcttgcga gatcatccgc aaagacttca aaggacactg
    15541 ggtagtctgt aattttggca agcacttctt tggcaaagcc aatataagaa ctgatgcctg
    15601 cttttttcat caaacttgga ttggttgtaa agcctgtgac caaacctgtt tgtaaatcct
    15661 ttaacatggt ctctaagacc gcaccgtctg aaaagacttt aacgtttagt ttttttgtca
    15721 tcatatcctc cttttagatt tctactgaaa cattattgat ggcttcttga gattttgaca
    15781 gaaagtttgg aagcaccaat acaatagcaa gcacagcaac caccaagtaa ataccgattt
    15841 gaccaatcga cgttcctaag cggcccagta aaatccctaa aacaccgaaa tccacatctc
    15901 caaaggtcgt gtttgaaaaa ccaagtttac caagtacagg tagaagcatg gctggcaaga
    15961 aggcgagtaa taagccatta gcgaagcacc aatcatcgca ccgcgacgac cacctgttga
    16021 atttccaaaa atctctgctg ttgcaccgca gaagaaatga ggcaccatac ctgggataat
    16081 caggacacca cctgcaactc ctaaaatcaa catcccaagt aagccaccaa cgaaacttga
    16141 cgcaaaaccg atgataacag cggttggcgc ataagggaag aataccgcac aatccacggc
    16201 tggaatagca tttggaatta atttgttagc aataccttgg aaggctggaa tcaagtcagc
    16261 caaaatcatg cgaacaccgg cgtagacaat tgccacacca accgcaaagg taagaccact
    16321 cttaatggca aaaataaatg ggttttgacc tgctgctaat tcttctgcta ctgaagcatt
    16381 cctcaaaaca gaagccactg ttgccaccaa gtagaaaatc accatgataa gtcctgttga
    16441 aatggtggtg ttgcgcaaga aactccattt ttcagaaatc tgaaggtctt cggtatcttt
    16501 actgtctttg ccaaccttgc taccaaccca ggcagaaagg taatagccca aactaccaaa
    16561 gtgtcccata gcgatttcat ctccgtcagt cactttcaga gtatactgtt gaccaatggc
    16621 tggcgaaata gctgaccaag ctcccaagag gaacccatct aagataatca aaagacttcc
    16681 tttgaaacca acagctccaa gcacggcgga caagagacaa gccataaaga agctgtgatg
    16741 tcctgttaag aaaatgtatt tgaagcgggt aaaacgagca aaagccaaat tgagcaataa
    16801 cccaaccacc aagatggaca tagtttccac acccagaatc ttttgagcga cagaagtgac
    16861 ggcttcgtta tttggcacta cgccagtgat gctaaaaccg tgctcaatga gtttggcaag
    16921 agggtccaaa ttggtcacaa taacacccgc ccctgcaaca agcataaggt atcccaaaat
    16981 cggccccaag gttcctgtca acaccttatg agcaggtgtt ttcaaagcca ccaaccctgc
    17041 aaaggcaatc aagcccatta aaaatgcagg ttcttttaaa atatctcgaa taaatgataa
    17101 taatgcttcc atagtatctt cctatttcct ttaaaggctt attccttgcc actcatttcc
    17161 ttgagaaccg gaaccaaatc ttcttcaatt tttttacgat tggtatagct tttaacgata
    17221 caaaccttgg catcctctgg aaaaatatct ttaaattctt taacggtaac aaacaaatct
    17281 gcaccctttc caacagccgc attggaatca caggattctg catccacatc aatacccaaa
    17341 ctagaggcga tagcttctac tttcatgcga agtaacaagc tactaccaat accgtttcca
    17401 caaaccgtta caattttaat catgtgattc gtctcctttt tcaatcatat ggctaatcag
    17461 actcattatt tcctcagtat tcttagcctc aattaattgc tcaatatgtt catcatcatc
    17521 taaaatcaac gacagttcct gcaaagcctt caaatgtgaa ctagaatcca cagcagacaa
    17581 aacaaaaatc aattgcactt gcttgtctgg atcaccttct tgcttcaaat caaagctgac
    17641 aggttctttt agttgtaaga gagacatgcc taactgccgc gttccttttt caggcgccgc
    17701 atgaggaaca gccaccttag gggctaaaac aatataggcc ccaagctcat tgaccgaatc
    17761 aatcatgcca tcgatataag atgtttcaat catctggtgt tctagtaaag gctgagcagc
    17821 caaacgaatc gcttcctgcc aatccgaaac agcatcagcc tgcctaataa aatctgctgt
    17881 taacaagtcc aatagtccta gacctccttt ttcaatcgtt aaatggttac caatcaggta
    17941 acgggataaa tcactaacaa gtccttcttt attagtaatc gtggtatgtt tatgaataat
    18001 actcaacaga tcatccaaag cgaattgctc tgacaaggga agatgaaagt catcacagac
    18061 catctttttc aacatcattt tttcaacagg tcccatcaaa gcttgcgtca cataaacagg
    18121 tttagcacag tcaaaagcta ctgttgaaaa aatcaaatca aaggatgctg gatccaacaa
    18181 ctttattttg tccagctggt gaatcctaat aaactgtagc tgtggaaaaa gttccttcaa
    18241 ggttgcctcc aacatcagag acgaactaat gccattaggg caaacagata aggctaccag
    18301 ctgattgctt ggcctcttct taggggcctg caaccatctc ccaaaatgaa tggtaaaata
    18361 agcaacctca tcttcattaa ctgatttccc caattgtttt tctagaggag aaaggctgcg
    18421 cttgaccaag taaaagagag attcataatc ttgtttgatt tgttccttca aaggattggt
    18481 caagttaatg tcgtagtaaa gtcggtaata agctggcaaa aggtgactgt ataggttctg
    18541 acgaagttct ggggtatcgg tgatagacaa tcccgtgtta accgccaccg aattgatgat
    18601 ttcctccata atgtcataaa taggttgctg aaagactaac tctaagtcac cttggataca
    18661 accaagtaac ctagattgaa ccaaatattt ttcttcggtt agactgggga agttgaccaa
    18721 taactggtcc accatcgttt caacagctgg cgaagctaaa ggaaaagtat ccactgcttc
    18781 agcccttacg ttccgtgaaa atggtcgatg agcgagaagg cagaaaaaat aaatcaaatc
    18841 cctcaatttc tccgaaataa aagttaagtg gttctccctg ctcagttcct ccaacgttgc
    18901 tgccatcacc tttttctggt cgggcaaacc aagttcatgc aataagtaac tgaacaccca
    18961 aggtccagat gtgacttgca aaagagaact gaccgctgat tctaagagac gccgcaaggc
    19021 taagggttct ccttcaaaaa aataaccatc ctggcgattg taagctaaag ttacctgaaa
    19081 agcttgtacc cgatcacgca ccaagtttaa atcagcaata acagaatttc tgctgagccg
    19141 taacaagctt tccaagtggt taatggagat aaattcttta gccatcatga tgtaaatgat
    19201 aatcatatcc agacgctcat cttgaaagag atagtcgtct aaggtaggta gcatgcgatt
    19261 caacaagtcc ttttcagtaa ggtctggcgg ataaaccagc tgcctgtcca gagcaataag
    19321 gggtaactga tagagtgaca acgtgtcatt gattttagca atatctgcca gtatatgacg
    19381 tttgcttgcc tttaaaatgg attcaaatgc ctccagtgaa tgtcctttat atttagaaaa
    19441 gagttgatag tttctgatga gctcatgaga tagcatgtca tctcctccta taatgtcagt
    19501 ataaaatgaa gcgttttcat tttcaagata aattgagtcc aattgtctca tgtcattttt
    19561 gactgcaatt ggactcaaca ggtgatatca ttgtaacaag ttcctcaaaa ggtggtcaaa
    19621 aataggcaaa tctgggaatt gattcccttt ttcttcatga tacaacaaaa gatacctcat
    19681 cactgagata ccttttgttg ttaaataaaa tcatcaactg ctaaaaaaac agtcttagac
    19741 cattctagcc aaatgtgtaa gttaacaaac aacatgtcaa aaatgaaaaa gcccactgca
    19801 taagcagagg actttttaaa cttgaaatta acgacgaagt ccaagagatt ggatcaactc
    19861 acggtaacgg ttaacatctg tacgacgtag gtatgccaac aagttacgac ggtgaccaat
    19921 ttttttcatc aatccacggt aagtagcgtg gtcttttttg tgttgtttga tgtggctgtt
    19981 caagtggttg atttcccaag taagaactgc tacttgaact tcaactgaac ctgtatcgcc
    20041 ttcatgacgt gcatattgag caatgatttc attttttttc tcttttgaga ttgccataat
    20101 atattctcct ttttttgctt aatccgagtc ttaggattgg cactcctaaa accaagaaaa
    20161 agttggtttg tctttcgacc actctattct agcagattca taatattagg tcaaccgtta
    20221 tcctattatt ctaagctctc acatccaaac caccttaagc aacagaacta gcaaggccaa
    20281 atagccaaga ggctgttttt aaatcagaat aaacctgtgc gattgcttgc ctaataagat
    20341 aaccagctaa aagaggtaag atggctgatc cccgcacttc agctgataag cggtaaccta
    20401 gcatagtcat tcatttcttt ccaacaaagt gttcactgat aatattaatt gctctagtat
    20461 taacaaaccc aatccctaat ccatgaacac agcttattaa ccgatgcgac ctgcctttat
    20521 gacataggtc aagagttgac acaaaatgtt tgccaacaaa acattaccta taccgtcaaa
    20581 gagcgctttg cttcctatac ccttgaagcg caagccaacc aagaggttca tctaaacctt
    20641 acattattag caaaccgttt tggaacaagc gatcgccatc ttaagcacgt acttaagcag
    20701 cccatttttc agaggattat cgaacgcatc tgcttcaaaa cctatcgtat tgccgattta
    20761 gacgctctaa ctcaattaag acctctgagg tatgcagccc attaacttat aatagcaatc
    20821 actctaacca ctatctgact tttctttaaa aaagaaatga tttgtgatat agtaaatcca
    20881 gttaaaaaaa agtaaaggag tagacatgtc tgcacaagat aaattaatta aacctagtca
    20941 tctgattacc atggatgaca ttattcgtga agggaatcca actttaagag ctgtcgccaa
    21001 agaagtgagc ttacccttgt gtgatgagga tatcctatta ggagaaaaga tgatgcaatt
    21061 tttgaagcat tctcaagatc ctgtaatggc ggaaaaactt ggtcttaggg ccggtgttgg
    21121 tctagcagct cctcagattg atgtgtcaaa acgtatcatc gctgtgctcg ttcctaatct
    21181 tcctgataaa gaaggaaatc ctcctaaaga agcctatagc tggcaagaag tcctgtataa
    21241 tcctaaaatc gtttctcatt ctgttcaaga tgcagccctt tctgatggcg aaggttgttt
    21301 atctgtcgat cgtgttgttg aagggtatgt ggttcgccat gctcgtgtta cagtagacta
    21361 ctatgataaa gaaggacaac agcatcgcat caaattaaag ggatacaacg ctattgtggt
    21421 tcaacatgaa attgaccata tcaatggtgt tttgttctac gatcggatca atgctaaaaa
    21481 cccctttgaa accaaagaag agctcttgat tttagactaa caaaaaaagg ccctttagcc
    21541 tttttttgtt agtctaaata gccgctaaaa gagcctctgc ctgagatagc aagtttgctt
    21601 ttgtctcttt tgaaatctca agccttcctg ttccccaggc atcaggattc acagttgctt
    21661 ttgtaaactc tcctgctact gaagttcgga taaacggcaa tagtgcttta aactgatcaa
    21721 atacttgatc atgcccgcca tttgcaactg aagagaccgt aaccacctta ccgccaatag
    21781 cagatgggcc cgtcggatca gacaaatcaa gagcacgaga caaccagtct agcaggtttt
    21841 taacagaacc tggaatagag aagttgtaaa ctggtgtaaa aatccagata gcatccgctg
    21901 actgaacagc ttgacgagcg tcaacaactg gtaaaggtgc attagcttcg atatcttgat
    21961 tcaaaacagg aacgtctttc caatttaagt aagatacaac tgcttgatgt tccagagctt
    22021 tttgtgcttg agccgctaat tgatggttaa aagacccttc acgaagcgag ccaacaataa
    22081 ataaaatatg tttcatctct ttgccctctt tttttaaaga tcgttttaaa gctttctaaa
    22141 agtggtattt cattgatact tctttttgaa atttatcact atgtagtaat tatatcttct
    22201 ctaagaagag ctgtaaagag atttgtttat aattgtttga actttttgag aagttcaatc
    22261 agacaaagtt gttctttttc agtcaaaaca gcaaaggctt cttccacccg tgcgacgtgt
    22321 ttaggcaaaa cagcttcaat caagcgagta cccttatctg ttaaggtaac cacataggct
    22381 cttttatccg ttttgtcttt gcacttgcta atccagccat tgcgttccat attatttagt
    22441 acaacagtca tattccccga agtcgctaac aaagaatcaa tcaagtgatt gattcgcata
    22501 cagcctttag tatatagtac ttcaagcaca ctgaactgcg tggctgttaa atctgccttt
    22561 ttaaaaatat cagccccaaa agcatctagc gttcgctgag ctttacgaaa caccaccatg
    22621 gctttcaaag cggtgttctt atctaaatga ctcatttgat ttcctcgctt tatacggtat
    22681 gtcacagttt agtatcagag agattagaaa gtgatcttgt ccctcttctt ttatgacttt
    22741 gcatattact atcatcatga taatctagaa aaagtcatca aaaagactta attgattatc
    22801 ttctggcata tttcctaaaa tacccatctc atccattttc tcaacgagcg ttgacgatgc
    22861 cccgcctcgt ttacgcaatt ccattttaga gaggaattcg ccttcttgac gagctttaac
    22921 gatttgcttg gccacgtttt cacccagacc ttctagcgct ataaatggag ggataagggt
    22981 atctcctttg atttggaatt ctatagcatc acttttgtaa aggtctaatt tgccaaactt
    23041 aaagccgcgt tctaacattt cgttgacaat ctccaaggtt gtaaagaggt cattttccac
    23101 attggtggct tcattatttt tacgttttat agtaatatct tccattcttg ctttaacagc
    23161 atctaaacca ccactcatgg tttttaattc aaaagccttc gcacgaatag agaaataagc
    23221 acaataatac ataatggggt ggtgcacctt gaaataagcc acccgaaggg ccatcaaaac
    23281 ataagctgcc gcatgggctt tagggaacat gtacttgatt tttccacacg attcaatgta
    23341 ccagtcgggc acattgtttt ctcgcatggc atcaatatag ccattacgtt cttcctcaga
    23401 aatttttagc cataatccct tacgcacacg ctccataatg gtaaaggcca tttttggttc
    23461 taagcctgcg tgcatgaggt aaaccatgat gtcgtcacga caaccgataa cggtttttag
    23521 ggttgcaatg ccttctttaa tcaaatcttg tgcattacca agccaaacat cggttccatg
    23581 agatagtcca gacaactgca aaagctccgc aaaagtggtc ggatgcgtct cattaaccat
    23641 gccgcgaaca aagttggttc caaattctgg aatgcctagc ataccagtcg gtgtcccaat
    23701 ttgttccggg gtaacgccca aaacctctgt cccagaaaag agagccataa ctcccggatc
    23761 atcagcagga atagtaatag gatcaatgcc cgataaatcc tgaagtttac gaatcatggt
    23821 cggatcatca tgccctagga tatcaagttt caagacgttt tcatcaatat catggaagtt
    23881 aaagtgagtt gtctgccaag aagccgttac atcatcggct ggatattgca cgggggtaaa
    23941 atcataaaca tccatgtaat taggaataac aacaatcccc ccagggtgct gcccagtcgt
    24001 tcgtttcaca ccagcagcac ctgctgctag acgatccacc tcagcatcac gatagaactt
    24061 gccatagtcg cgttcatagc ctttgacaaa tccataagct gttttttctg ctacggtacc
    24121 aactgttcca gcacgaaagg cgtattcgtc accaaaaata tctcggacat ccaaatgggc
    24181 actgggctgg tcatcaccag agaagttcaa atcaatatcg ggcaccttat ccccatcaaa
    24241 cccaagaaag gtctcaaagg gaatgtcttg cccatctttt tgataagggg tgccacattt
    24301 cggacagggt ttattaggca aatcatagcc agatccaact gacccatctg tgataaattc
    24361 agaatgttgg caggacgggc aaacgtagtg aggcggcata ggattaacct cagtaatccc
    24421 aatcatggtg gcgacaaagc tagaccctac agatccccta gaaccaacta ggtagcctcg
    24481 ctcatttgac cggttaacaa gcatttggga agcgagataa atcacagcaa aaccgttccc
    24541 caagatagag gttaactctt tttcaatgcg taaatcaata atatctggga gaggattacc
    24601 ataaatttca aaggcttttt gataggttaa ttcggcaacc gtctcttcgg ccttatcaat
    24661 atacggggtg taaagatcgc ccttaaccac ttccacttcc tcaatacggt ccgcaaaatc
    24721 ctgagtattt tgcacaacta cttgataagc gaggtctttt ccaagaaagg caaactcatc
    24781 cagcatttca ttggttgttc taaagtgcgc tttaggtaga ggagcaggct gtgccccttc
    24841 cccacggccg attgttctat taatcatggc accctgacca agactacgca caataatttc
    24901 acggtaaatc tcttcttcag gctctagata atgcacattc ccagtggcaa gcacaggttt
    24961 cttagctcgt ttccctactt caatgaggtc acgaatcacc tgctcaatac ctgcttgatc
    25021 tttgattaat tcacggacaa ccaatggctg gtaaatggct ggtggcatga tttcgataaa
    25081 atcataatac ctagccaaat caaccgctgc atcaattcct ttagtcagaa cggcatcaaa
    25141 aacctcgccg tcagaacaag ctgtaccaag taacaaaccc tctctgtgag catctaagac
    25201 ggttcttgga atacgcggca ccccttcaaa atatttgata ttggaaaggc tgaccaactt
    25261 aaacatattt ttaagaccaa cctgattttg cacatagata gtcgcatgct taatccgcgc
    25321 ttttttgtaa gaatcctcag ccaccaaatc tgtattgagt tgcaaaagat ttttgatgcc
    25381 atgcttttct ctggcatctt ttagaaaaat aaacaaaaga cgtcctgtgg cttccgcgtc
    25441 gtaattggcc atatgatggt ggtctagact cacttggaaa cgcttggtga gcggtcccaa
    25501 accgtgacgc ttgtactcag gatacaagtt tctagcaaat tctaaggtat caatcacagg
    25561 ctgtgtgatt ttgggcaagt cgtggcgttc ataattggcg ttcataaagc ccacgtcaaa
    25621 actggcgttg tgggcaacca agatactatc tttgcaaaag tcctgaaaag cttttaggac
    25681 agtaaccaat ggcttggcgc cctgcaaatg cttatcggta attcctgtca attcggtggt
    25741 aaaggctgaa agaggatgcc caggatcaat gaattcatca aactgctcta caatatttcc
    25801 tttaaacatt ttggaagccg caatctgaat caggtcatta ttcatagcag atagacctgt
    25861 ggtttccacg tcaaagacca cataggtagc ttcgtgcaaa tccatatcaa caggttcata
    25921 agaaataggc accttgtcct caacaatatt ggcttctagg ccaaaaatag ccttaatccc
    25981 agctttgcga gccctatggt agccatgagg aaaactttgc acattagcat ggtcggtgat
    26041 agcaatcgcc ttgtgtcccc acttggctgc cgtatcaatc aagctttcta ctgtcggtaa
    26101 ggcatccatg gtagacatat tggtgtgggc atgaagttcg acccgctttt gcccttctgg
    26161 catcaggtct ttgcgctcat gacggacaat ttctttgacc tgctggacat tcatggtgag
    26221 actcttcgta aaaggattgg tctcaatatt cccttgtacc cgtaaccaag ctcccttagc
    26281 aatcatatca aatttacgga gctcctcatc gtctttagcc catttttgga gagcaaacga
    26341 ggaggtatag tctgtcattt taaagttgat gatatggcga cctgtcctag tcgttttacg
    26401 ctccacgtca aaaaccatac cctcaaagac aatccggttt tcttcggtct caatctcaat
    26461 cattggtgtg atggttgctt tttcaaaccc tgcctgacgc ttagctgctc gttccttgta
    26521 gtcaaactta ggagcaggtg tggcttcctc aactggtggc atcatggctt caagagattt
    26581 ttgggcttcc aaattatcct gcacagcctt tttcacaaga gcctgacgac tggaaacaaa
    26641 attcttggtc aaatgctcag tcatttcctg atctgacacc atatctatgg tcaaggtgcc
    26701 aaagccaaag gcttctaatt gcttgaccag attaggcaga tgattgtttc taaaatgatc
    26761 gttattcaca aaacctggcg ctgcaataat gagtttgtca tcctcataag tcactttgag
    26821 ctttgagaaa gaagatttaa aactagcact attacacggt gcatgctcaa aagcttcttg
    26881 gtaataagct tgaagcagat catctgaata atccacctga gcagcttgga tgtcaaaggt
    26941 taccttaatg tcagccgcct caaaagttct tatcaaacga tcatgcaatt cacgataagt
    27001 tgcaatcggt aaaaccgctg caaaggcaaa atgaaattcc cacaagcgtg acaccgaatg
    27061 tacctttacc tcgataatat cagcagatga aaaggcactt gaacgtctca tgtcaagtgg
    27121 catttctatc tggtccatca atttagcgaa taaatctgac ataattttct cctgatttta
    27181 ctaggcttta ttttatcaca attcaagatg attttcgagt tttagatgga aagaaaagca
    27241 gggctttctt ctgacgttct ttggctaatt tattccaagt gatagctcag ttgaggtcat
    27301 tttttttgcc aatcttttat cgccaagcgc ttttggtaaa gcaaaagcca ctctgtatca
    27361 gacaagttca cagcaaaaag aggccactct aaacaggcag cctcttcatt tcttttttag
    27421 tgttcttttg ttaaaatttc aagggtttcg atgaggtttt ctgcattaac ttcaatgctg
    27481 tcacctgttg ccttgatttt aatttccacg ataccttcag cggctttttt accaacagtg
    27541 acacgaattg gcaaaccaat caaatcgcta tcagagaatt tcgaaccgac gcgttcatta
    27601 cggtcatctg tcaagacatc atacccttta gccatcaagt cagcttctaa cttcgccgtc
    27661 aagtcttggg ccacttgatc tttgacatta actgtaatca aatgcacgtc aaatggggct
    27721 aattctttag ggaagttaat accccaagca taacggtaat cgccttttgg tgtcttgttc
    27781 acaaagagac gggcatgctg ttcaatgaca gcagacaaaa tgcggctaac cccgatacca
    27841 taacaaccca tcacaattgg aactgttctg ccattttcat caagaatcgt tgctcccatg
    27901 ctgtctgaat aacgagtgcc caacttgaag atatgaccga cttcgatacc acgcgcaaac
    27961 tggagaacac catgaccgtc cggagacatt tccccttctt tgacttcacg aatatctaca
    28021 tattcagcct ggaagtcacg tcctggattg actcctgtca tatggaaacc atccttgtta
    28081 gctcctgcaa cggcattggt aaggttttgc actttgcggt cagccacaat acgactacct
    28141 tgtgccaagt tgacaggccc aagtgagcca aaacctgcac caaagaaagc acgggcttct
    28201 tcttcactag ctggctctaa aaaatcagca gctagatagt tttttaattt aacggtattg
    28261 atatggtcat ttccaactag caaagcaaca acaggttcat tatctgccac aaaaagcaag
    28321 gttttgatgg tttgtgtttc atctactgaa agaaaagcag ccacttcatc aatcgttttg
    28381 caatgtggtg tctcaacttc tgccaaggca tcttcagcag ctacttttga ggacggtttg
    28441 tattcgttag ttgccatctc aaggttggca gcgtagcttg attctgttga ataagcaata
    28501 gtatcttcac ctgaaatcat ccaagcagcc aattctgcct taatatcttc taagacctct
    28561 tttggaatat catccattga cgcaatagac ttgtcaagaa ccacccagcg atcaagatcc
    28621 gtacgagctg gtgtaatggc cataaattct tgggaatctt tcccccccat ggcaccgcca
    28681 tctccaataa tccctttgaa atctaaacca gctctggtaa aaatagcttc gtaagcttga
    28741 cgataatctt cgtaggtcac atctaaatct tcatagttgt gatggaaact atagccgtct
    28801 ttcataataa actcacgggt acgaagcaag ccattacgcg gacgtttttc atcacgatac
    28861 ttagactgaa tttgataaag gtttaagggc aattgcttgt aagatttgac cgcatcacgc
    28921 accaaagtcg taaaggtttc ttcgtgagtt ggacccaaga taaagtctga gttatcacgg
    28981 tttttaagct tatagaggtc ctctccatag gtctcataac ggcctgattc acgccagaga
    29041 tcagctgtca aaagagctgg cgccaacatt tcaacagcac cgatcttttc aaactcttca
    29101 cgcatgatgg tcttgaattt ctcaatggta cgatttgcca gtggtaaata agcatagata
    29161 ccagcagaaa cttggcgcac ataaccggca cgcaccataa gcgcgtggct gataacctgg
    29221 gcatcacttg gcatttcgcg caaggttggg ataagcagtt tactttgttt catagattat
    29281 tccgttttaa tacatcccct tatcctcaaa cccttctgga aacatcaagt aagagtgaag
    29341 cgggattatt caataatttg aatgtgtatt cctttcattt tgagtaagac ctcaaccctt
    29401 gcaaatctta gggttgaggt ctttttcgat ctttaacatg ataaggtcag cttaagatga
    29461 cctatcttga ttagaaaaag acgcgcatga tatcattcca tgtcacagca atcatcaata
    29521 cgaccatgat agcaacccca gctagggtga tataggcctc tgtttcttgc ttgataggct
    29581 tgcgacgaat ggcttcaatg atattcatca agatttttcc cccatcaagt gcaggaatcg
    29641 gaatcaggtt aaagatccct aaattgatcg aaagcattgc cataagagat aagactgact
    29701 ctaagccgtt ttgagcagcc tgattggaca tgtcatacat ggcaacaggt ccacctaatt
    29761 tattgagact aaagccagtg atcaatcctt tcaaagcatt caaaatagta aacgccctac
    29821 tccaagctaa ttctagaccg cctaagagct tatccttaaa tcctgttttc agactcgcct
    29881 taactcctat cgtgtatgtc tttgcatgct tttgtggttt cacagccacc gtttttaagc
    29941 gctgatgtga cttgtaggtg accttaatgg tctgtgacgg gcctagatcc cgtgttgcaa
    30001 ggtctacagc ctcagtgaga tcattccagc tagtcacctt gtaaccatta attgcgacaa
    30061 tttggtcatt atctcgaaga ccagccttag ctgctgctcc attttcttga acacggacat
    30121 gattgctact aaaatctggc atcccacctt gtaaaaagac caagaggata aaaaccacaa
    30181 tccctaaaat aaaattattc atgggacctg caaaattggt gattaaacgt ccgccaatac
    30241 tagcattttg atattgaaca tcaagcggag caattcttat ctcagtaccg tcttcttcaa
    30301 caatagtagc atcgtgagcg accttatatg tcttggtttc ttctaaaact aagccagtaa
    30361 tactcagctg atcttctaag tcatagcctg taacatgcat tgggagactc gttgggtcta
    30421 acttactttg agacaagttg atgcgcttaa caaaaccttg ctcattaagg gttaaacttg
    30481 ttggagtacc tgttttgatc tcagttttgt catcacccca accagccatt cgcacataac
    30541 cgcccaaggg taacatcctc aaggtataaa gagttcctcc ttggtcaaca tgagaaaaaa
    30601 ttttagggcc cattccaatg gcaaattctc ttactagaat gcctgatttt ttagcaaaat
    30661 agaaatgtcc aaattcatgg acaatcacta aaataccaaa aataataata aaggttatta
    30721 ttcctaacat agatttcctt tcagtctatt gcttttttga gttttgtcgc gttgttgcga
    30781 ctccaaacat tacctcttaa gattaaaata aaccaaagag atgcatgatg ggaaaaacaa
    30841 aaatcatgga atcaaagcgg tctaaaatac caccatgtcc cgggataagc ttacctgaat
    30901 ctttgacacc aaagtgacgt ttgagagcac tttcaaccaa atcaccaaat tgggcaaaaa
    30961 tggaaaaaag agcgaccaaa accaacatgg tcaaaaagtg atgtggcgca taaacagacc
    31021 tatcaatcac cataaagata aaagacacaa ggactgcaca agcgatccct cctaaactac
    31081 cttcaatggt tttgtttgga gaaactgtag gcaatagttt gcgtctacca aactgacgcc
    31141 caatcagata tgctccaata tcagtggccc aaacgataaa taaggccaaa aagaccttgt
    31201 caattcctga caggcgagca ttgatcaaat gttgaaaacc aatcccaaca taaaaactag
    31261 ttgcaatcgg aaaggccgca tcatcaaatg aataagctct gctatttaaa acagtacctg
    31321 ccaaaatgaa aaaaaccatt aagctgtaaa aagcaacatt cgcatcaatt ggtaaaaaag
    31381 tgaggtaatg gtccatcgga actgccaata caaaggcggc taacatggca aaaacacctt
    31441 caaaagaaaa gacttctaat cttttcattt tcagtaattc tgatacccca atcatggcca
    31501 aaacgcctac aaataattgg aatggtaggt ttcctattat gagaaaaggt aggaaaatag
    31561 ctactgctac tcccccccaa acaacacgtt ctttcataac tatctccttt tagaccttgc
    31621 caaaacgacg ttggcggcgg ttataatccg caatggcctt tagtagctct gcctttttaa
    31681 aatcaggcca caagactggt gtgaaataaa attcactgta agctgattgc caaggcaaga
    31741 aattgctcaa acgcagctca ccactggtgc gaataatcaa atcggggtct cggtagagat
    31801 atggcagatg gtctgtcatc aagtaattag caatcaaatc ctccgtaata tctcctggat
    31861 ttaatttggc atctaagaca tcttgagcaa taaagcgaac agcactggta atctcagcac
    31921 gtcctccata attgagagca aaattcaaaa ttaaacccgt attacgtttt gttttgtcga
    31981 tggctgcatt tagcgctgcc aaggtatctt caggtaaacg actagtctct ccaatcattt
    32041 gaatctttac attgttctca tgaagcacag gcacatattt gtcaaagaag gttactggta
    32101 aattcatgat aaaagacacc tcatcttggg gtctggacca gttttctgtc gaaaaggcat
    32161 agactgtcag aactttaacc cccaactcag atgcagtaat cgttacttct tgtaaagcat
    32221 ccatcccagc tttatgccca aacactctag gttttagtct ttttttggcc caacgtccat
    32281 taccatccat gataattcca atatgctttg ggatactccc caaaactttt tttgttgatt
    32341 tcgcttttaa tccaaacatg ttttttcctt attgataagc atacttatct catattttat
    32401 catatttcac gccttttggc ttgtttttta tcaattagat cttatcttca caaaatgttc
    32461 acctatcctc tgatagatgt gtcagctttt catgaacctg ttagcatcag aataactgtt
    32521 tcaatccagg gatcaaaaca aaaaagtttg gcatatttca tccaaacttt ccccgcctta
    32581 atggctttca atggcactgt cagtgtcagt gctatctact gtctcaacag caggctcatt
    32641 aacaacactg gtttcttctg tttcaaccag tgtcgtttct gtagtagctt ttgttacaat
    32701 acgcttaata gctaatagct caaatgtcaa aaagacgcca tccacatcta acacaatctt
    32761 tttagctgtt gtatcgactt cgtcaacaat cgcaaacatg ccaccaatcg ttacgacttc
    32821 gtctcctttt tcaatagcgt ttaactgatt ttggcgttct tgcgcttgtt ttttttgttg
    32881 acgttgcata aaccaaatca atccaagcat cactacaaac attaaaattg ttggaaatcc
    32941 cataatgtct cctttttatt ctataaaagt catgtcttac tatatcaaaa atcaagcggt
    33001 atagcaagac tagacgttac ctgatgtctt ctttaaacga gacgctaagc gcagtgcttt
    33061 actcacgagt caaaaaagct aagatgtcat ctggtgtcaa acttgaatca catacagccc
    33121 tttggtgctg atcgtaacta accagcaaag ctggaactgt cactaattgg tagttctcac
    33181 gaaaggcagc aagctcagca gcatcagcag cgttttcgct atccacaaaa tagacttctt
    33241 tttgattatc tgttgctact tgtgccaact tgggagcaaa gcggcgacaa taaggacagc
    33301 tcgaacgtcc taaaaagaca atcatgtctt tgccactagc gatagctgat gtgacttctg
    33361 caacactcga cggtataaaa ttcgcaacga tttcttcaaa tgtcatggat gtctccttct
    33421 cttttggtct catgatacac taaagtagca attttctcaa tcacaaggtc ttttcacagc
    33481 tcagagcttt tatagccgtc aaaaagaatc cgcaaacagc aatctttttg tctctattaa
    33541 caccacccta atctttttgg cgcttcatca acaggctaat agccaataaa agcagagcta
    33601 ttccagctgc taataagcct tttgaggagg cttcacccgt ttttgggagc ttttggtttg
    33661 ttttagctct ttttggtcta gtcattaatg atttgtctag gtcttttgag ccatctggtg
    33721 ttttggtttg atgattgtct gtctgactct tttgctgaga gggattagcc gtttttgagg
    33781 atactttgag gaccagggca gttaggcctt caatagtcaa gccttctttg gtaaactgga
    33841 ctcccttagg cttagcaatg gcagtaacac cagcttgctc agcatcaaca agcacttggg
    33901 ctcctagcaa atagcggtag gcttgaggta aaactacctt gcgggtcttg ttgtctgcat
    33961 tgacaaagac agcatagcga tctccatttg atgccactgt ttggtaaccc atgatgaggt
    34021 cctcttgttg aataccatct tgtcctgctt gggtgatcaa ggtcacatcc cgatctacct
    34081 cagctttggt tgcttttgta aaggcatctg ttgagcgacg caacgcaatt agtccctgtg
    34141 tataggcttt tgtttggttg ctaatcgggt gagctatgga atctgttgcc tttgcccagt
    34201 caaaatgatt gaccgcatca gacgaatcat aagaatcgtg gatgaagtaa gggtattgcg
    34261 ctacagcatc aatcagagtc gccttatttg gcaccttgtc atcagacgcc tttgtcttgt
    34321 agtcgggatt tagaagctgc ttggttcgtc catattcctg accagaatgg ataaaggcag
    34381 tcccttgagc agttaaaatc atggtatttc ctagacgaat acgcttgtga atctcttctt
    34441 cagccacttt aggatcctta ttgatggatt tggcaatgac atcatgtaag gtcaggttgt
    34501 catgggctgc aatatactgc actacatctc ctggggcatc tgcttcaaag ttaccaggct
    34561 gtgctttgat cgttttgaat aaaccttcta gattttttgc gccaccagta ataaaggctg
    34621 ctgtgccttc atttggaaaa cctgacttga gggtatttct gatatcatca gagaaaacac
    34681 cgaccgtatt ggttgctttc atccaatctt gatctgccgc aatttctttt ttcccctcat
    34741 caccttggta ggtacgccag ccttcgccaa tcataatggt atttggatta atggctttgg
    34801 ctgccttaaa ggcttgctca atagctgccg catcatggtc acccatcatg tcgaaacgaa
    34861 aaccatctac cttgaattca cgagtcagat aagtaatcga atccaccaag atacgacgac
    34921 tcatggcatg tgtcgttcct agacgacctc cgccaaaact ctctctagct gtaccatcag
    34981 cattcataaa atgatagtag ttgggttcca aatcttcaaa gagataggtt ctagccgtgt
    35041 ggttataaac cacatcaaaa ataacaccca taccacgttt gtgaatctca ttgacaaggt
    35101 ttttaagctc tgcgatacgt aaagcagggt cattaggatt tgccgaatac atgccagaaa
    35161 gggcaaagta gtgttgtggg tcataacccc agttgtaatt attgtctgaa gacgtgtagg
    35221 ctgttgagcg gctcttgtcc agctcattgg cataaaaata actcaaaacc ggtagcaatt
    35281 gaacgtgggt aacccccaag tctttgagat agtctagctg ttcaacgaaa gctgaaaaag
    35341 tcccaaaagg gtgtgttaac ttgccttcta gagccttatc tgacgtaaaa tctcgcacat
    35401 gtgcttcata gataatagcg tcttcacgct ttttaaagtt gttaattttg gcaaaatcaa
    35461 ggcctgttgg tcctagtttg cttggatcaa taaaggcagc ttttgctgtt ttgatgtcat
    35521 cagtagcagt cgcatcattc caggcagcga gagatttggc gtaaggatcc aaaaccatga
    35581 ctttttcctg accgcgcgtg atttcataaa ggtaatagta gcctgtgtaa tcactaatgc
    35641 ccttgacact gtcagaagtt agatgagctc tccaaacacc cttgtccgac ttggtcaaat
    35701 cagcttgacc aaccaccctt gtctgatctt gtttatcata aacgacaacc ttaacagtat
    35761 cagcacttgg agaccatagc gctaaatcaa cagaaccatc cttagctagg gtagctccaa
    35821 gttcaccatc gtaagcatag agtttatctt ttaattgcca ggattggcga gcgacttggc
    35881 taacttctcc aaatgtaacc gtgtagactg caccttgcgc cttaaaatca ccctttaatg
    35941 tcattacaga cttatccctg tcaagtgtca actcatcaat tgcaacagtt ttccctgctt
    36001 tgtcagtgat cttgatgttt tgtttcaccg catcttcatc aagcccatct aaggtcgtaa
    36061 aaatggcttt aatctcattt ggcgtggttt gttcagctcc tttgagacta acctgatcaa
    36121 tataataagg attgttgtaa acttttgggt cagtgtcttt gacaaaaacc tgagtatgat
    36181 tgtctaactc tttaaataga taatcttttg gttgcacttt aatagcatct cctgtcttac
    36241 ttttatcaag gattaaaaat ccgatttcgt tagctccttc ttttaagggg acatcaacat
    36301 aagctccata atgcccttta tgtgacaagt caagtccatt tggccagtcg gtcgttgggg
    36361 ttttgacatc tttaaaggtc cagacagcta agttatcgta gtgtcccgat tgattgtggt
    36421 agttgattcg aaggtaacct tttttcaaag gtcgataagc gtgcgcatgg taattctcgt
    36481 ctatccaaac ttcattcatt tttggcgtga gaagcgagat gtgctggtcc tttgaaagat
    36541 tctctccagc tttattatta atgagataag acacttgctg gcggtgttta gctgctagtg
    36601 gcacatctag ataatagcca tagtcatctt ttttcgcttt tgtcatggtg atagcaccat
    36661 ttggccaatc ctttgaaggt tgatccacat ctccccacac ccaaagtccc aagcttccta
    36721 gcgactcacc agctggcaat gttttaaaat gcatacgcaa atgatgctca gcaatactag
    36781 caggattagc tgacgagctg tctaaaactg gttttgcctc cttgctagac gattgaagac
    36841 catcaccaga tttagcattg ccatctcctt gttgagcttc atcgcgggct agtccaacaa
    36901 tggttttagc agcaacttga tgtgttaaga tactaggggt gcaccctaac acgacagtcc
    36961 cagttgcagc gattacaaaa cctatccccc acttttttaa cagatattga tagcgctttg
    37021 atccttggtt gactttcttt ttcataagac ctccatttag tataacattc aaacaagact
    37081 atcttatcac attgcgcaag cgcttgcaag acatgccgca cttcaactta gaacacagct
    37141 caaacaatga ctatcacccc ttaataggat ctcaaaaatt aaacagccaa aacgagtttc
    37201 cactcgcttg gctgttgggt aaactcaaat cacatacagc tgctaggcct tcagtttgag
    37261 acaaaaggca tcccaaggtt gtaagtgctt ggtctctaat accgtgtcca catctgtatt
    37321 ggcgatgatc acttgtgcac ctgctaagtc tgtggcaaag acttgctcct catcagacac
    37381 attgacaaca atcacatacg tctcttctcc aagctgacgc tgataagcaa acactttatc
    37441 agctgttggc aagaggtgat aatccgcttc aactagccag tcttgctcct tacgcaaggc
    37501 aatcaatttt tggtaggtgt aaaaaataga gtctggatca gcaagggcat cggccacatt
    37561 gatgtcttgg tagttggggt tgaccggcaa ccaagtctct tttgcttcag aaaagccagc
    37621 atgtgtgtcc ttagaccact gcatcggcgt tctagcattg tctcgtccta ccttacggat
    37681 gctatccatc acacgcgcag ctgacactcc atttcccata gcttccttag catagttaag
    37741 ggactcaata tcattaacct cggttaagtc tttaaaagga taattggtca tgccaatctc
    37801 ttctccttgg taaatgtaag gggttcctcg catcaaatgc agtaaaatag ctaaagcctt
    37861 ggctgatttt tctcggtaag tgctgtcatt gccccaaatg gataagaccc gtggcaagtc
    37921 atggttattc caaaaaagcg aattccagcc ttctcctaac tttaattctg tctgccactt
    37981 gctaaaaata gctttcagag caggcacgtc taattctttg gcataatccc acttgggagc
    38041 gtcaggttta tgttgaagac ccacatgctc aaattggaag accatggata actctttgtt
    38101 ttcagggcga gaatactggc gagcaatttc aggcgttgct ccccaagtct caccgactgt
    38161 catcacgtca tggttgccaa aggttgcttg attcatttct ttgaggtaat cgtgtaagcg
    38221 cggcccgtta cccgtgatct ccaagtcagg aaccttccca atcaggtcaa tcacatccat
    38281 acgaaaacca ccgatgcctt tggcaatcca gaaattcatc atatcgtaaa ttttttggcg
    38341 cagctgagca ttttcccagt tcaaatcagg ctgtttcttg ctaaacaaat gcaggtaata
    38401 ttgtcctgat gcctcatcca attcccaagc agatcctgaa aaaatagaca tgaggttgtt
    38461 tggctcgtca cgccaaatat agtaatcacg ctcaggacta ttgggatttt ctctagcttc
    38521 aacaaaccaa gcatgctcat cagacgtatg gttgaccacc aagtccatga taatcttaat
    38581 gcctcgctca ttagctgctg ctaagagctc atccatatct gccatgtctc caaaaacatc
    38641 agcaatcgct tcatagtcag agatgtcata accattgtca tccattggac tttggtaaac
    38701 aggagataac caaatggctg taatgccaag tttttgcaag tagtccagtt gactggtaat
    38761 gccttttaaa tcaccaatac cattgccgct ggtgtcttta aaggaccttg ggtaaatctg
    38821 ataaatcgta gctttatgcc accagtgttt cttcattatt cttctcctat taatcattca
    38881 ttcatctttt attttaacgt tttttctctt tttgtgcaat cgtttgcgca aataacatga
    38941 taaaaaggct ggaacccaac ctttttatga atatcgctta taccttaacg aatagcttgt
    39001 tcggtatctc tgtcaaagaa atgcccctta gccacattaa aggtcaagct aacttgctcc
    39061 cctggactat ggaaatcacg cgcatctaca cgagaagcaa actcagtttg tccaagcttg
    39121 acatagagca tcgtctcaga gcccagtaac tcagaaacca aaacttctgc tgtgacagtt
    39181 gcacttggat aagtatcatg cacgatttgt ctactagaaa tgtcttctgg acgaatacca
    39241 aaagtgactt tttccccctt gtaaccagca gcttcaagca tttttgcttg tccttctgga
    39301 atagcaatgt caagaccatc ttcactcaca atgcggccat ctttaacttc cacttcaaaa
    39361 aagttcatgg cagggcttcc gataaaaccg gcaacgaatt tattagctgg aaggttgtac
    39421 aattcttgtg gcgagccgac ttgctcaatt ttaccaatcg ttccattacc ttgagggttt
    39481 ttagtggcac tcatgataac gatacggtct gccaaagtca tggcttcggt ttggtcatgg
    39541 gtaacgtaaa tagttgttga gccgatacga cggtgaattt tagcaatttc agcacgcata
    39601 gacacacgaa gcttcgcatc caagtttgac aaaggctcat ccatcaagaa taccttagca
    39661 tcacggacaa tagcacgccc catggcaaca cgctgacgtt gaccaccaga caggtcagcc
    39721 ggtttacgct ctaaaaattc ggtcaaacca agaatctgcg cagcttcctt gacacgacgg
    39781 tcaatatcat cttttttgta cttacgtaat ttcaaaccaa aggccatgtt atcatacaca
    39841 gtcatgtgtg ggtaaagggc gtagttttga aagaccatgg caatatcacg gtctttagga
    39901 gacttgtcat tcaccacttc gccaccgatt tttaactctc cttcagaaat gtcctcaaga
    39961 cctgcaatca tacgaagagt agtcgattta ccacatcctg aaggtccaac aaagacgata
    40021 aattctttgt ctttaatgtc taagtcaaaa tcttcaacgg cataatgagt agtatttggg
    40081 tattttttat agatgtgatt tagatttaat tcaaccatgt gtaactccta tttgaacagc
    40141 aaacgttcta gctgactgca aagctagaaa ccactgatat cttttatatg atgcttttat
    40201 tataacaaaa atagcgcttt caaaacagag acaaagcgac caaacttctt tgggcaactt
    40261 gcacaatagc agggctagtc aagtcgtaaa gacccataaa acaagaaaac catgtaaaca
    40321 caggccggtc acaggagcca aaacaagctg aacgatctat cattctccct atcagctaca
    40381 gtccaggcag caaaaaagaa agccctgtgc ctttcctaat atttcaacaa aaagagatga
    40441 gcaaaggcta aatcatccaa ttgcttcaag tggagtcctg attgctgagc aaatttatca
    40501 agtttgtatt gcaaggagtt acggtgaata tacaagcgct gcgctgtctg caccagattg
    40561 ccgtgttctg accatagcgc gtgaaccaca tcggccatat cactttgagg acttaggaat
    40621 tggtgaaact gacgcgtcaa tgccaaaaaa gtgtggtgcg acagcaaaga ccacagcatc
    40681 agtcctgaaa atgttaataa ttttctgcct gattgttgcc ttaaataggc cgttaacagc
    40741 tgacattcct cctcaaaaca ctctctcaat gtacccgcag ctacctgata ccaggcattt
    40801 ccaacaaaca tggttaaggc caaaccaaaa tcactttcta gcgttggcag gagatcttca
    40861 agccagcgca agacctttat tgagattgct tgtcggcata aaaatgccgt ttgggttgca
    40921 ctgataggca aaatgacttc aagccctgca atcatttgtt ggagcaactc aactaagtca
    40981 tctggtaaag cctgctgatg attaaggtaa atgaactgag aagtctcata cagctgaggg
    41041 ggattgccct gatgatcaag caaataccgc tgccaaggtg accctagcgg ctgcaagacc
    41101 tcacactgac ccagccccac ctcaagtaat aagcgctctt tttcggataa acatgatttg
    41161 ggaaaatgca catattggtc cccttctttg atactcatcc aatctttatc tcctaacgga
    41221 tgagggccta cttgcatctc tggaaaatag tcttttagct ccatagccat tcctttcatg
    41281 acggtcttta aaccattata acacatgact ctttatcaca cagttcggtt tgttgtcagc
    41341 acgattttgt attttctgcc tttttaatca ttaaagctaa ataatggtta ttcattttta
    41401 gcaagaacat tcaatcaaat ggctatttat cggaagatta atttaattta ttggaagatt
    41461 aatt
//
LOCUS       DAUGQX010000012        41130 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUGQX010000012 DAUGQX010000000
VERSION     DAUGQX010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41130
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.012"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            18..98
                     /locus_tag="VIA51_000566"
     tRNA            18..98
                     /locus_tag="VIA51_000566"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VIA51_000567"
     tRNA            105..175
                     /locus_tag="VIA51_000567"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VIA51_000568"
     tRNA            187..259
                     /locus_tag="VIA51_000568"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VIA51_000569"
     tRNA            268..339
                     /locus_tag="VIA51_000569"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VIA51_000570"
     tRNA            359..442
                     /locus_tag="VIA51_000570"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            1300..2139
                     /locus_tag="VIA51_000571"
                     /pseudo
     CDS             1300..2139
                     /locus_tag="VIA51_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
     gene            2208..2651
                     /locus_tag="VIA51_000572"
     CDS             2208..2651
                     /locus_tag="VIA51_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEQ8682530.1"
                     /translation="MGILEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2655..3374
                     /locus_tag="VIA51_000573"
     CDS             2655..3374
                     /locus_tag="VIA51_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682531.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEAETDDEKGGHGHA"
     gene            3367..4182
                     /locus_tag="VIA51_000574"
     CDS             3367..4182
                     /locus_tag="VIA51_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8682532.1"
                     /translation="MLDILFYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4222..4605)
                     /locus_tag="VIA51_000575"
     CDS             complement(4222..4605)
                     /locus_tag="VIA51_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8682533.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEGHYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWEGITINQENWDLTPFLKHL"
     gene            complement(4656..5912)
                     /locus_tag="VIA51_000576"
     CDS             complement(4656..5912)
                     /locus_tag="VIA51_000576"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEQ8682534.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSIDNHNIVEILVAAKISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6004..8316
                     /locus_tag="VIA51_000577"
     CDS             6004..8316
                     /locus_tag="VIA51_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8682535.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGIVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLFNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8580..12146
                     /gene="rpoB"
                     /locus_tag="VIA51_000578"
     CDS             8580..12146
                     /gene="rpoB"
                     /locus_tag="VIA51_000578"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8682536.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGTVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQQ
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12237..15878
                     /gene="rpoC"
                     /locus_tag="VIA51_000579"
     CDS             12237..15878
                     /gene="rpoC"
                     /locus_tag="VIA51_000579"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEQ8682537.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDRLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVIPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16030..16395
                     /locus_tag="VIA51_000580"
     CDS             16030..16395
                     /locus_tag="VIA51_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEQ8682538.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16488..17426
                     /gene="tadA"
                     /locus_tag="VIA51_000581"
     CDS             16488..17426
                     /gene="tadA"
                     /locus_tag="VIA51_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEQ8682539.1"
                     /translation="MVQALAKAILAKAEQVHAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17410..18396
                     /locus_tag="VIA51_000582"
     CDS             17410..18396
                     /locus_tag="VIA51_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEQ8682540.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18398..18724
                     /locus_tag="VIA51_000583"
     CDS             18398..18724
                     /locus_tag="VIA51_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEQ8682541.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18699..19127
                     /locus_tag="VIA51_000584"
     CDS             18699..19127
                     /locus_tag="VIA51_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEQ8682542.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19132..19368
                     /locus_tag="VIA51_000585"
     CDS             19132..19368
                     /locus_tag="VIA51_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8682543.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEMTLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19361..19795
                     /locus_tag="VIA51_000586"
     CDS             19361..19795
                     /locus_tag="VIA51_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEQ8682544.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19779..20105
                     /locus_tag="VIA51_000587"
     CDS             19779..20105
                     /locus_tag="VIA51_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8682545.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20203..21156
                     /locus_tag="VIA51_000588"
     CDS             20203..21156
                     /locus_tag="VIA51_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8682546.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21215..22411
                     /locus_tag="VIA51_000589"
     CDS             21215..22411
                     /locus_tag="VIA51_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEQ8682547.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22598..22906
                     /locus_tag="VIA51_000590"
     CDS             22598..22906
                     /locus_tag="VIA51_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682548.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLPLIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(22989..23759)
                     /locus_tag="VIA51_000591"
     CDS             complement(22989..23759)
                     /locus_tag="VIA51_000591"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEQ8682549.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLA
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL"
     gene            complement(23807..24874)
                     /gene="pepA"
                     /locus_tag="VIA51_000592"
     CDS             complement(23807..24874)
                     /gene="pepA"
                     /locus_tag="VIA51_000592"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEQ8682550.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
                     IIPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEEAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKCY"
     gene            25330..25623
                     /locus_tag="VIA51_000593"
     CDS             25330..25623
                     /locus_tag="VIA51_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEQ8682551.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25620..25937
                     /locus_tag="VIA51_000594"
     CDS             25620..25937
                     /locus_tag="VIA51_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEQ8682552.1"
                     /translation="MIRPTSYESLATLIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25955..26581
                     /locus_tag="VIA51_000595"
     CDS             25955..26581
                     /locus_tag="VIA51_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEQ8682553.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDENLARLNAELAKEGFSERLEPIVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIEFDESAVVGEAFDPAKHWKG"
     gene            26733..27128
                     /locus_tag="VIA51_000596"
     CDS             26733..27128
                     /locus_tag="VIA51_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8682554.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27388..28029)
                     /locus_tag="VIA51_000597"
     CDS             complement(27388..28029)
                     /locus_tag="VIA51_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEQ8682555.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIERRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYEVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28049..29026)
                     /gene="dusB"
                     /locus_tag="VIA51_000598"
     CDS             complement(28049..29026)
                     /gene="dusB"
                     /locus_tag="VIA51_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEQ8682556.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(29013..29885)
                     /gene="hslO"
                     /locus_tag="VIA51_000599"
     CDS             complement(29013..29885)
                     /gene="hslO"
                     /locus_tag="VIA51_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEQ8682557.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIISDKA"
     gene            complement(30032..31525)
                     /gene="rofA"
                     /locus_tag="VIA51_000600"
     CDS             complement(30032..31525)
                     /gene="rofA"
                     /locus_tag="VIA51_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEQ8682558.1"
                     /translation="MIEKYLESSIESKCQLIVLFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSHDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQYCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRDLNHKHFHLFCHYVEQSLRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
     gene            31788..34061
                     /gene="cpa"
                     /locus_tag="VIA51_000601"
     CDS             31788..34061
                     /gene="cpa"
                     /locus_tag="VIA51_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus tip adhesin"
                     /protein_id="HEQ8682559.1"
                     /translation="MKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSM
                     VGAKTVFGLVESSTPNAINPDSSSEYRWYGYESYVRGHPYYKQFRVAHDLRVNLEGSR
                     SYQVYCFNLKKAFPLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKLRAVMY
                     NGHPQNANGIMEGLEPLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLS
                     LMRQALKQLIDPNLATKMPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPP
                     TPGDPPMPPNQPQTTSVLIRKYAIGDYSKLLEGATLQLTGDNVNSFQARVFSSNDIGE
                     RIELSDGTYTLTELNSPAGYSIAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVE
                     AYNDFEEFSVLTTQNYAKFYYAKNKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTT
                     GEVKYTHIAGRDLFKYTVKPRDTDPDTFLKHIKKVIEKGYREKGQAIEYSGLTETQLR
                     AATQLAIYYFTDSAELDKDKLKDYHGFGDMNDSTLAVAKILVEYAQDSNPPQLTDLDF
                     FIPNNNKYQSLIGTQWHPEDLVDIIRMEDKKEVIPVTHNLTLRKTVTGLAGDRTKDFH
                     FEIELKNNKQELLSQTVKTDKTNLEFKDGKATINLKHGESLTLQGLPEGYSYLVKETD
                     SEGYKVKVNSQEVANATVSKTGITSDETLAFENNKEPVVPTGVDQKINGYLALIVIAG
                     ISLGIWGIHTIRIRKHD"
     gene            34054..34611
                     /gene="sipA"
                     /locus_tag="VIA51_000602"
     CDS             34054..34611
                     /gene="sipA"
                     /locus_tag="VIA51_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase-like pilus assembly factor
                     SipA"
                     /protein_id="HEQ8682560.1"
                     /translation="MTRADFRTSNSSGELNKLSFSDKEAIKPLLIGLVKKIALILIGG
                     YLLFHFVFGFMIIKRNDMAPSVKAGDAILFYRLSQTYKVEEAVVYEDSKTSITKVGRI
                     IAQAGDEVDLTEQGELKINGHIQNEGLTFIKSREANYPYRIADNSYLILNDYYSQESE
                     NYLQDAIAKDAIKGTINTLIRLRNH"
     gene            34644..35666
                     /gene="fctA"
                     /locus_tag="VIA51_000603"
     CDS             34644..35666
                     /gene="fctA"
                     /locus_tag="VIA51_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus major pilin FctA"
                     /protein_id="HEQ8682561.1"
                     /translation="MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSN
                     ALIPNTDFTFKIEPDTTVNEDGNKFKGVALNTPMTKVTYTNSDKGGSNTKTAEFDFSE
                     VTFEKPGVYYYKVTEEKIDKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGS
                     KVPIQFKNSLDSTTLTVKKKVSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKG
                     GQAPVQTEASIDQLYHFTLKDGESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQD
                     GAVKNIAGNSTEQETSTDKDMTITFTNKKDFEVPTGVAMTVAPYIALGIVAVGGALYF
                     VKKKNA"
     gene            35676..36389
                     /gene="srtC1"
                     /locus_tag="VIA51_000604"
     CDS             35676..36389
                     /gene="srtC1"
                     /locus_tag="VIA51_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus polymerization class B sortase
                     SrtC1"
                     /protein_id="HEQ8682562.1"
                     /translation="MIVRLIKLLDKLINVIVLCFFFLCLLIAALGIYDALTVYQGANA
                     TNYQQYKKKGVQFDDLLAINSDVMAWLTVKGTHIDYPIVQGENNLEYINKSVEGEYSL
                     SGSVFLDYRNKVTFEDKYSLIYAHHMAGNVMFGELPNFRKKSFFNKHKEFSIETKTKQ
                     KLKINIFACIQTDAFDSLLFNPIDVDISSKNEFLNHIKQKSVQYREILTTNESRFVAL
                     STCEDMTTDGRIIVIGQIE"
     gene            36411..37058
                     /gene="fctB"
                     /locus_tag="VIA51_000605"
     CDS             36411..37058
                     /gene="fctB"
                     /locus_tag="VIA51_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-2 pilus minor pilin FctB"
                     /protein_id="HEQ8682563.1"
                     /translation="MKKSILRILAIGYLLMSFCLLDSVEAENLTASINIEVINQVDVA
                     TNKQSSDIDETFMFVIEALDKESPLPNSVTTSVKGNGKTSFEQLTFSEVGQYHYKIHQ
                     LLGKNSQYHYDETVYEVVIYVLYNEQSGALETNLVSNKLGETEKSELIFKQEYSEKTP
                     EPHQPDTTEKEKPQKKRNGILPSTGEMVSYVSALGIVLVATITLYSIYKKLKTSK"
     gene            complement(37245..38567)
                     /locus_tag="VIA51_000606"
     CDS             complement(37245..38567)
                     /locus_tag="VIA51_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003627959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEQ8682564.1"
                     /translation="MTCPVETEDITYRRKKIKGRRQAILAQFEPELVHHELIGDSCTC
                     PDCHGTLTEIGSVVQRQELVFIPAQLKRINHVQHAYKCQTCSDNSLSDKIIKAPVPKA
                     PLAHSLGSASIIAHTVHQKFTLKVPNYRQEEDWNKLGLSISRKEIANWHIKSSQYYFE
                     PLYDLLRDILLSQEVIHADETSYRVLESDTQLTYYWTFLSGKHEKKGITLYHHDKRRS
                     GLVTQEVLGDYSGYVHCDMHGAYRQLEHAKLVGCWAHVRRKFFEATPKQADKTSLGRK
                     GLVYCDKLFALEAEWCELPPQERLVKRKEILTPLMTTFFDWCREQVVLSGSKLGLAIA
                     YSLKHERTFRTVLEDGHIVLSNNMAERAIKSLVMGRKNWLFSQSFEGAKAAAIIMSLL
                     ETAKRHGLNSEKYISYLLDRLPNEETLAKREVLEAYLPWAKKVQTNCQ"
     gene            complement(38530..38757)
                     /locus_tag="VIA51_000607"
     CDS             complement(38530..38757)
                     /locus_tag="VIA51_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8682565.1"
                     /translation="MSSQDKVIKTQAKTIETMANELALLREQVAYLTQKLYGKSSEKA
                     MPMTGQLSLFDQDQLPEEADDLPSRNRRHYL"
     gene            complement(38808..39158)
                     /gene="tnpB"
                     /locus_tag="VIA51_000608"
     CDS             complement(38808..39158)
                     /gene="tnpB"
                     /locus_tag="VIA51_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEQ8682566.1"
                     /translation="MTIRLNDLGQVYLVCGKTDMRQGIDSLAYLVKSQHELDLFSGAV
                     YLFCGGRRDRFKALYWDGQGFWLLYKRFENGKLAWPRNRDEVKCLTAVQVDWLMKGFF
                     ISPNIKISKSHDFY"
     gene            39388..40217
                     /locus_tag="VIA51_000609"
                     /pseudo
     CDS             39388..40217
                     /locus_tag="VIA51_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936782.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
     gene            complement(40411..41076)
                     /locus_tag="VIA51_000610"
     CDS             complement(40411..41076)
                     /locus_tag="VIA51_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682567.1"
                     /translation="MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKKLVDSDKNIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPTEITYEHHY
                     WDGTVRSETRNNTQWHYDWKSQQTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEDNYKNKWDKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
BASE COUNT        12676 a         7279 c         8657 g        12518 t
ORIGIN      
        1 aaagtttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tgtaaacctt gttttttgtt
      481 ttgatcttaa gctgtagcta cgtagtacaa tctcttatat tactgataag gtctatttaa
      541 tgcgcaagat ttgtggtatg atgaatatga ttgagtattg atgctttatg ggattaccgg
      601 taaggttttg aaaaaggttt gtcactacta ggtgcttttt taactataga aagacagtta
      661 tggattgatg tattgtaact aatgttggag gttaatggtg gttgagtttt gagatattta
      721 cactgataat cgggtggaaa ctggtcgggt atcgggtaat ggagtgtggt tcttcgttta
      781 agcaaggaga ttatcgtttg gtggttcata tttgcttgtt aaatgttagg gatgagatgc
      841 tgagtcagca aggccatgaa gataaagctg actggctaga gccttgagat gtgacgtttg
      901 gtggaagtcc tttttggtga gatggcacag catatagtaa tattagatcc tgaggaagaa
      961 ttgggacttt cattaggctt gactggggta tgacctcact ttacaattca tttcgatgat
     1021 gggtttgatg atacgttttt agttcaagac tttgtagagt tggagaattt ggttctttat
     1081 gaagaagaag tgcaggtaat tcgttgagcc agtcgtgaag atattttagg tatgattgat
     1141 gaaggttcgt ttattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggc
     1201 caatataaag tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt
     1261 atatttgata gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga
     1321 gcttctgtaa aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac
     1381 gatttatcga tggtcatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata
     1441 gatgacaata agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat
     1501 gatgtttata agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc
     1561 gtttacttgg aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct
     1621 gttactatca gagcattaaa tcagatggct ccttactctt agccgaaaag atatgatgga
     1681 tattggtata ccgattggta gtgatgtgcc ttattgcttg ctttcaggtt gtgcccaagt
     1741 cactggtaaa ggtgaagtgg tttgtcgcat tttggggctg ttatcgtctt gggtggtttt
     1801 ggttaaacca gattttggta tctcgacttg aacatttttt ctagatatta attgtaaaat
     1861 catttcaaga gtgtctacta ctcatttggt tgcggcgatt gaagcgggta actataatga
     1921 tgggatattg actgaaatga acaatttgct ggaagatatt ttcattgcca agcgaccctt
     1981 tattcaaaaa ataaaagaga aaacactgca agctggtgct gctaatgctt tgatgacagg
     2041 aagtggaccg actgtttttg ctttgtgcca aaccgaaaaa caaactataa tagtttaaaa
     2101 ggactttgca aggaagtttt taaggtgaga atgttgtaat attttgttgg gattgcttct
     2161 ttggaagctt catgttataa ttaactggtt aatgaaagag gagatttatg gggattttag
     2221 aaaaaaaact tgataactta gtaaatacta ttttattaaa agcagaaaat cagcatgagt
     2281 tattatttgg agcttgtcaa agtgacgtta agcttactaa tacgcaagaa catattttaa
     2341 tgttactatc tcagcaacgt ctcactaata cagatttggc taaggcatta aatattagtc
     2401 aggcggcagt aactaaggct atcaagagtt tggtcaaaca agacatgtta gcaggaacta
     2461 aggatacggt tgatgctagg gtgacttatt ttgaattaac cgagttagct aagcctattg
     2521 cgtcagaaca tacccatcat catgatgaaa ccttaaatgt ttacaaccgt ttattacaaa
     2581 aattctccgc gaaagaatta gagattgtag ataagtttgt aacagttttt gctgaggaat
     2641 tagaagggta atccatgaga tacatatcag tgaaaaatct ctcctttcaa tatgaaagtg
     2701 agccagtttt agaagggatc acttatcatt tagatagtgg agaatttgtc accatgaccg
     2761 gtgaaaatgg tgctgcaaag tcaaccttaa taaaagcaac cttaggaatt ttacaaccaa
     2821 aggctggacg agttactatt gctaaaaaaa ataaagacgg taaacaatta agaattgctt
     2881 acttgccgca gcaagtagct agctttaacg ctggttttcc atccaccgtt tacgagtttg
     2941 tcaaatcagg tcgctaccca cgtagtggtt ggtttagaca tttgaacaaa cacgatgaag
     3001 agcatgtgca agcaagctta gaagcagtcg gcatgtggga aaaccgtcat aagagaattg
     3061 gtagtttatc aggtggtcaa aaacaacgtg tggttattgc ccgtatgttt gcttctgacc
     3121 ctgatatttt tgtgctagac gagccaacaa cgggaatgga tagcggtact actgatacct
     3181 tttatgaact gatgcaccac agtgcacatc aacatgggaa atccgttctg atgattaccc
     3241 atgacccaga agaagtgaag gcttatgctg atcggaacat tcatttagtc agaaaccaaa
     3301 aacttccttg gcgttgtttc aacattcatg aagctgaaac agatgacgaa aaaggaggtc
     3361 atggtcatgc ttgatatttt attctatgat ttcatgcaac gggcggtaat ggcggtagtt
     3421 gccattagta tttttgctcc gattttaggt attttcctta ttttacgtcg tcaaagtttg
     3481 atgagcgata cccttagtca tgtttctttg gctggggtag cgcttggggt agtccttggt
     3541 atttcaccaa ccatcactac tattattgtt gtggttttag ctgctatttt gttagaatac
     3601 ctgcgtgtag tttacaaaca ctacatggag atttcaacgg cgattttgat gtcacttggc
     3661 ttggccctat ctctgattat tatgagtaag tcgcatagtt catcaagcat gagtttagaa
     3721 caataccttt ttggatcgat catcacgatt agtatggaac aagttgtcgc cttgtttgct
     3781 attgctgcga ttattttaat cttgaccgtt ctcttcatta gaccgatgta cattctgacc
     3841 tttgatgaag atactgcttt tgtagatggt ttgcccgttc gcttgatgtc tgttctattc
     3901 aatatcgtca ctggggttgc tattgctttg accattccag cagcaggagc acttttggtt
     3961 tctaccatta tggtcttgcc agcaagtatc gcaatgagat tgggtaaaaa ctttaaaaca
     4021 gttatcttac tgggaattgt catcggtttt agcggtatgt tatctggtat tttcttatct
     4081 tatttctttg aaacgccagc tagtgccact attaccatga ttttcattag tattttcctc
     4141 ttagttagtc taggtggaat gcttaaaaaa cggttatttt aataagaaaa atcctcacat
     4201 gtttaacatg tgaggattta tttataaatg ctttaaaaag ggggtaaggt cccaattttc
     4261 ttgattaatg gtgatgccct cccaaaagct atcattagtt aaacgaggaa tcaaatgaag
     4321 gtgaaaatga gtcccctcat ccatcaactc cttgtcattg ctgacgctag taacgcctga
     4381 aatgggaagg tgctgctcta gcttagcaac tagagcggct tgtaagtcga tgagatcata
     4441 gtgcccttcc tttggtagtt gtgtcagact agtgtaatgg tctttggaaa tcagtaaaag
     4501 gtgccccttt tggataggat cgatatcaaa aacaaccttg aaatattgac tttgagtcag
     4561 tagctgattt gctttgagct gatggcaaaa gatacattct gtcataggta catctcctta
     4621 tgaaaaaacg agccagagct cgtttaatcg gttatctagt aagtgagaac agcgtatttt
     4681 ttcttaccgc ggcgaataac ggttaattga tcatcaattt tatcatcatt acttaattgg
     4741 taatctaaat cttgaacgcg gtctccgtta atgtagattg ctccattttg cacgtcttca
     4801 cgcgcctggc gttttgatgg ggaaatctta gcagctacta aaatctcgac aatattatga
     4861 ttgtctattg attgaacgtg ataatttggt acattgctca atccttgttt taattcattg
     4921 gcagaaagat ttttgatgtt tccagcaaat aactgctcgg taatgttaag agcttgttta
     4981 taagcttctt cgccatgaac caaggtaacc acttcgcgtg ccaaggtttt ttgagcgaga
     5041 cgctcgtgac gagcggcatt aaattgagtt tcaatttctg caatctcatc tagagataag
     5101 aaggtgaaga ttttcaagaa acgcactgca tcatcatcca tgacatttaa ccagaattgg
     5161 tacatctcgt aaggagacgt cttatcggca tcaagccaga cagcattacc ttctgattta
     5221 ccgaattttt tcccggttga gtcagtgatg agtggtacag tcatgacgtg cccagtttta
     5281 tcagcctttt tgcggagcaa ttcagtacca gctgtcatat taccccactg gtcagagccg
     5341 ccaatttgta aggttacatt atgcttgtca ttgagttcgt agaagtcgta gccctgcatg
     5401 atttggtaag caaactcagt gtaagaaatg cctgtttcaa tgcgtttttt aacagagtct
     5461 ttactcatca tgtagttaac ggtgaagtat ttaccgacat cacggaggaa gtcaataaag
     5521 ctgatttgcg agaaccagtc gtagttgttg acaagctctg ctttattatc accattttca
     5581 aaatcaagga aagtagacaa ctgcccttta atcttgtcac tccactccaa aactgtttct
     5641 ttggtttgaa ggctgcgctc tgcatcttta aaggaaggat caccaattaa acctgtggca
     5701 ccccccacaa gagcgtaagg tttgtgccct gctagttgca agcgacgaga tgttaagata
     5761 gccactagat ggcccagatg aaggctgtca gcggttggat cataaccggt ataataggat
     5821 acttgccctt ctgttaatgc tttgacaagg gcttgttcat cagtcgtttg aaagaccaag
     5881 ccacgagctt tgagttcttc aaaaatattc ataggctttc tccattttca ttatagtttc
     5941 gaatcattat atcaaaaaac gctactgcta tgcaagcttt atcaaagttt ggtataatga
     6001 taaatgaggt attttatggt gaaatggaac acgaaacaaa agcgtataag tcatcaaaga
     6061 ttaggtctct tggatttggg gccggtgcta ttacgtacgt tgagactact gtctaacttt
     6121 ttttatattg ttatcttcct ttttggaatg atgggatttg gtatggcatt tgggtatttg
     6181 gctagtcaga ttgaatctgt taaggtacca agtaaagaaa gtttagtcaa acaagttgaa
     6241 tcattaacga tgatttcgca aatgaactat tctgataata gtttaatttc tactttagat
     6301 acggatttac ttcgaacacc agtagctaat gatgcgattt cagagaatat caaaaaagct
     6361 attgtatcaa cagaagacga acattttcaa gaacataaag gtatcgtgcc aaaagctgtt
     6421 tttcgggcaa cattggcttc tgtattggga tttggagaag ctagtggagg ttcgacctta
     6481 acacagcaat tagtcaagca acaagttttg ggagacgatc ccacatttaa gcgcaagtct
     6541 aaggagatcg tttacgctct tgccttagag cgttatatgt ccaaagacaa tatcttatgt
     6601 gattatctta atgtttcacc ttttggccgt aacaacaagg gtcaaaatat tgctggtgtt
     6661 gaagaagctg cgcgtggcat ttttggcgtt tctgccaaag atttaacggt gccacaggca
     6721 gcatttttgg cgggtcttcc gcagagtcct attgtttact ctccttattt gtcaacggga
     6781 caactgaaat cagaaaagga catggcttat ggcatcaagc gtcagcaaaa tgttctcttt
     6841 aacatgtacc gtacaggtgt tctgtctaaa aaagaatacg aggactataa ggcttatccg
     6901 attcaaaagg attttattca accgggaagt gcaatagtaa ataatcacga ttacctttat
     6961 tacacggtgt tagcggatgc taagaaagcc atgtatagct atttgattaa gcgagataag
     7021 gtgtctagtc gtgacttgaa aaatgacgag actaaggctg cttatgaaga gagagcctta
     7081 acagaattgc aacagggtgg ctataccatc accacaacca ttaataagcc tatttacaat
     7141 gcgatgcaga cagcggcagc tcagtttggt ggcttgttag atgatggcac tggtacagtt
     7201 caaatgggaa atgtcttgac agacaatgcg actggtgctg tgttaggttt tgttggtggt
     7261 agagattatg ctctgaatca aaataatcat gctttcaata cagttagatc gccaggttct
     7321 agcattaaac cgataatcgc ttatggtcct gctattgatc aaggtttaat ggggagtgct
     7381 agcgttttgt ctaattaccc aacaacttac tcgagtggcc aaaaaatcat gcatgctgat
     7441 agtgaaggaa cagccatgat gccacttcaa gaggccctaa atacttcttg gaacatccca
     7501 gctttttgga cacagaaatt actgcgtgaa aaaggtgtcg atgtcgaaaa ttatatgaca
     7561 aaaatgggtt ataagattgc agactactcg attgaaagtt tacctctagg gggcggtatt
     7621 gaagtctcgg ttgctcaaca aaccaatgct taccaaatgc tttcaaacaa tggcttatat
     7681 caaaagcaat atattgtaga taagattact gctagcgatg gtacagtcgt ttacaaacat
     7741 gaaaataagc caattcgtat tttttctgca gcaacagcta cgattttaca agaattgttg
     7801 agaggtccga ttacttcagg cgctacgact actttcaaga accgtttggc ggctattaat
     7861 ccgtggcttg ctaatgctga ttggattggt aagaccggaa caactgagaa ttatacggat
     7921 gtttggctag tcctgtctac tccaaaagtt actttaggcg gttgggcagg acatgatgac
     7981 aatacctcat tagcgccatt aacaggatat aacaataatt ctaattatct tgcctattta
     8041 gctaatgcca ttaatcaggc cgatcccaat gttattggag tagggcaacg cttcaactta
     8101 gatccaggag tcattaaggc gaatgtcttg aagtcaacag gtttacaacc aggaactgtt
     8161 aatgtcaatg gacatacttt ttctgttggt ggagaaatga ccaccagtct atggtcccaa
     8221 aaaggaccgg gggctatgac ttaccgattt gctattggtg gcacggatgc cgattatcaa
     8281 aaagcctggg ggaacttcgg gttcagaaaa aattaggttg ccatttatcg ataaaaaggg
     8341 tataatagta ataactattt gtcgtccaat ctagctgaaa tattgtccag ttaggaagaa
     8401 cagcagttaa atcacactga taaagtcaga tttagctgct ctttttgtgt ctatttttag
     8461 aaaagatagg gtttgtaacc tatatttaaa tattctaaaa attaacattt agggcaaatg
     8521 ataacttagt tgcgatttgc tgaaacagca aagcttaaat agaagaagga gctaaaaact
     8581 tggcaggaca tgaagttcga tacggaaaac accgtacacg tcgtagcttt tcaagaatca
     8641 aagaagttct tgatttacca aatttgattg aaattcaaac tgactcattc caagatttcc
     8701 tcgattcagg tttgaaagaa gtatttgaag atgtacttcc tatttcaaac tttacggata
     8761 ctatggaact tgaatttgtt ggttacgaat ttaaagaacc taaatatacc cttgaagaag
     8821 ctcgtatcca cgatgcaagt tattctgcac caatctttgt taccttccgt ttggtcaata
     8881 aagaaactgg tgagattaaa actcaagaag tcttctttgg tgatttccca atcatgacgg
     8941 aaatgggtac ctttattatc aatggtggtg aacgtatcat cgtttctcag ttggtgcgtt
     9001 ctccaggtgt ttatttcaac gataaagttg ataaaaacgg taaagttggt tacggatcaa
     9061 cagtgattcc taaccgtggg gcttggttgg aattagagac tgactcaaaa gacattgcct
     9121 acactcgtat tgaccgtacc cgtaagattc cattcacaac cttggttcgt gcccttggtt
     9181 tctcaggtga tgatgaaatt gttgatatct ttggtgaaag cgaccttgtt cgtaatacca
     9241 ttgaaaaaga cattcacaaa aatccaagtg attctcgtac agacgaagcc cttaaagaaa
     9301 tttacgagcg tcttcgtcca ggtgagccaa aaactgcaga tagctctcgt agtcttttga
     9361 ttgcgcgttt ctttgatgca cgtcgttacg atttggctgc ggttggtcgt tacaaagtga
     9421 acaaaaaact taatatcaag actcgtcttt tgaaccaaat cattgctgaa aaccttgtgg
     9481 atgctgaaac tggcgaaatt ttggtagaag ctggaactga gatgactcgt agcgtcatcg
     9541 aatccatcga agaacacctt gacggtgatt tgaacaagtt tgtttacaca ccaaatgatt
     9601 acgctgtggt tactgaacca gttgtccttc aaaagttcaa ggttgtgtca ccaattgatc
     9661 ctgatcgtgt agtaactatt gttggtaatg ccaatccaga tgataaggtt cgtgcattga
     9721 cacctgctga tattttggca gaaatgtctt acttcttgaa ccttgctgaa ggtcttggaa
     9781 aagttgacga tattgaccac ttgggtaacc gtcgtatccg tgccgttggt gaattgcttg
     9841 ccaaccaatt ccgcatcggt cttgctcgta tggagcgtaa cgtgcgtgag cgtatgtctg
     9901 ttcaagacaa cgatgtgtta acaccacaac aaatcatcaa tatccgtcct gtcacagcag
     9961 ctgtcaaaga attcttcggt tcgtctcagt tgtcacagtt catggaccaa cacaacccat
    10021 tgtcagagtt gtctcacaaa cgtcgtttat ctgccttagg acctggtggt ttgacacgtg
    10081 accgtgctgg ttatgaggtt cgtgacgtgc attacacgca ctatggccgt atgtgtccga
    10141 ttgaaacacc tgaaggacca aacattggtt tgattaataa cttgtcttca tttggacatc
    10201 ttaataaata tggtttcatc caaacacctt accgtaaggt tgaccgtgcg actggtacgg
    10261 taactaacga gattgtttgg ttgactgccg acgaagaaga cgaatacaca gttgcacagg
    10321 ccaattcgaa actaaacgaa gatggcactt ttgctgaaga aatcgttatg ggtcgtcacc
    10381 aaggtaataa ccaagaattt tctgcaagtg ttgttgattt cgttgacgtt tcccctaaac
    10441 aggtagttgc tgttgcgacg gcatgtattc ctttcttgga aaacgatgac tccaaccgtg
    10501 ccctcatggg tgccaacatg caacgtcagg ctgtgccatt gattgatcca aaagcaccat
    10561 atgttggtac tggtatggaa tatcaagctg cccatgactc aggcgctgcg gtgattgctc
    10621 agcaaaatgg taaagttgtc ttttctgatg ctgaaaaagt ggaaatccgt cgtcaagatg
    10681 gctcgcttga tgtttaccac attaccaaat tccgtcgttc aaactcagga acagcctata
    10741 accaacgcac ccttgttaaa gtaggagaca ttgttgaaaa aggtgatttc atcgctgatg
    10801 gaccttctat ggaaaatggt gaaatggctc ttggacaaaa cccagtcgtt gcttacatga
    10861 cttgggaagg ttataacttt gaggatgccg ttatcatgag tgagcgcctt gtgaaagaag
    10921 atgtctacac atctgttcac ttggaagaat tcgaatctga aacgcgtgat acaaaacttg
    10981 gccctgaaga aatcactcgg gaaatcccaa atgttggtga agaagccctc aaagaccttg
    11041 acgaaatggg cattatccgt atcggtgctg aggttaaaga aggcgacatc ttagtaggta
    11101 aagtcacacc taaaggtgaa aaagaccttt ctgctgaaga acgtttactt cacgccatct
    11161 ttggggataa atcgcgtgaa gtgcgtgata cctcacttcg tgtccctcac ggtggtgatg
    11221 gtatcgttcg tgatgtgaaa atctttacac gcgctaacgg cgatgaattg caatcaggtg
    11281 ttaatatgct tgtgcgtgtt tacatcgctc aaaaacgtaa aatcaaggtc ggagataaaa
    11341 tggccggtcg tcacggaaac aagggtgtcg tttcacgtat tgtaccagtt gaagacatgc
    11401 cataccttcc agatggaaca ccagttgaca tcatgttgaa ccctcttggg gtgccatcac
    11461 ggatgaatat tggtcaggtt atggaacttc accttggtat ggctgctcgt aatcttggta
    11521 ttcacattgc aacacctgtc tttgacgggg cttcatcaga agacctttgg gacactgttc
    11581 gtgaagctgg tatggatagc gatgctaaga cggtccttta tgatggtcgc accggtgaac
    11641 catttgacaa ccgtgtatcc gttggtgtca tgtatatgat caaacttcac cacatggttg
    11701 atgataaact tcatgcccgt tctgtaggac catactcact tgttacccaa cagccacttg
    11761 gtggtaaagc tcaatttggt ggacaacgtt ttggtgagat ggaggtttgg gcccttgaag
    11821 cttatggtgc atcaaatgtt cttcaagaaa tcttgaccta caagtcagat gacgtcacag
    11881 gacgtttgaa agcctatgaa gcgattacta aaggtaaacc aattccaaaa ccaggtgtac
    11941 cagaatcctt ccgtgttctt gtaaaagaat tgcaatcgct tggtcttgat atgcgtgtgc
    12001 ttgacgagga tgataatgaa gtggaacttc gtgatcttga tgaaggtgaa gacgatgaca
    12061 ttatgcatgt tgacgatctc gagaaggcac gtgaaaaaca agctcaagaa actcaagaag
    12121 tttctgaaac aactgacgaa aaataagcaa tcaattctta ttaaataatt atttactggt
    12181 ctggggcaaa ggccccagga actggtaaag tcatcaaagg cagaaaggta aaactagtgg
    12241 ttgacgtaaa tcgttttaaa agtatgcaaa tcacattagc ctcaccaagt aaggtccgtt
    12301 catggtctta tggtgaagtt aaaaaacctg aaacaatcaa ctaccgtaca ttaaaaccag
    12361 aacgtgaagg actctttgac gaagtcatct ttggtccaac aaaagactgg gaatgtgcgt
    12421 gtggtaagta caaacgtatc cgttataaag ggatcgtttg tgatcgctgt ggggttgagg
    12481 taactcgtgc taaagtacgt cgtgaacgta tgggtcacat tgagttaaaa gctcctgtat
    12541 cacatatctg gtatttcaaa gggattccat ctcgtatggg attgactctt gatatgagtc
    12601 ctcgtgccct tgaagaagtg atctattttg cggcttatgt ggtcattgat ccaaaagata
    12661 caccgcttga accaaaatca ttattaacag aacgtgaata ccgtgaaaaa ctacaagagt
    12721 atggtcatgg gtcatttgtc gctaagatgg gtgctgaagc cattcaagat ctcttgaaac
    12781 gtgtggactt ggcagctgaa atcgctgaat taaaagaaga gttgaaatct gcttctggtc
    12841 aaaaacggat taaagcagtt cgtcgtttag acgtccttga tgcctttaac aaatctggaa
    12901 ataaaccaga atggatggtt cttaacatcc tgccggttat tccaccagat cttcgtccga
    12961 tggttcaatt ggatggtggt cgttttgcgg catcagactt gaatgacttg taccgtcgtg
    13021 tgattaaccg taataaccgt ttggcacgtt tgttagaact taatgcccct ggcatcattg
    13081 ttcaaaatga aaaacgaatg cttcaagaag ccgttgatgc tttgattgat aatggtcgtc
    13141 gtggtcgtcc aatcactgga ccaggaagtc gtccattgaa atcattgagc cacatgctta
    13201 aaggtaaaca agggcgtttc cgtcaaaact tgcttggtaa acgtgtagac ttctctggac
    13261 gttccgttat cgctgttggt ccaaccctta aaatgtatca atgtggtgtc ccacgtgaaa
    13321 tggctatcga gctttttaaa ccatttgtaa tgcgcgaaat tgttgccaaa gaatatgctg
    13381 gtaacgttaa agccgctaaa cgtatggttg aacgtggcga cgaacgcatc tgggatatct
    13441 tagaagaagt tatcaaagaa cacccagtcc tacttaaccg cgcaccgact cttcacagac
    13501 ttggtattca ggcttttgaa cccgttctta ttgacggtaa ggcacttcgt cttcacccac
    13561 ttgtgtgtga ggcctacaat gccgacttcg atggagacca aatggccatt cacgtgccac
    13621 tttcagaaga agcacaagct gaagctcgtc ttttgatgct tgctgcagag cacatcttga
    13681 accctaaaga tggtaaacca gttgttactc catctcagga tatggttctt ggtaactact
    13741 atcttacgat ggaagatgct ggtcgcgaag gcgaaggtat gattttcaag gataaagacg
    13801 aagctgtgat ggcatatcgt aatggttatg ctcatcttca tagtcgtgtg ggtatcgctg
    13861 ttgacagcat gccaaacaaa ccttggaaag acaatcaaag acataaaatc atggtgacaa
    13921 ctgttggtaa gattctcttt aacgatatca tgccagagga ccttccttac ctccaagagc
    13981 caaacaatgc caacttgaca gaaggaacac ctgataaata cttccttgaa cctggtcaag
    14041 acatccaaga agtgattgat cgcttagaca tcaatgtgcc atttaagaag aaaaacctcg
    14101 gtaacatcat tgcggaaacc ttcaaacgtt tccgtacaac agaaacatca gccttccttg
    14161 accgcttgaa agaccttggt tactaccact caacccttgc tggtttgaca gtgggtatcg
    14221 ctgacattcc tgttattgat aataaagctg aaatcattga tgctgctcac catcgtgttg
    14281 aagaaattaa caaagccttc cgtcgtggtt tgatgacaga tgatgaccgt tatgttgccg
    14341 ttacaacaac atggcgtgaa gctaaagaag cccttgaaaa acgtctgatt gaaacacaag
    14401 atcctaagaa cccaatcgtt atgatgatgg actcaggagc tcgtggtaac atctcaaact
    14461 tctcacagct tgctggtatg cgtggtttga tggctgctcc taacggacgc atcatggaac
    14521 ttcctatctt gtcaaacttc cgtgaaggtt tgagcgtttt ggaaatgttc ttctcaaccc
    14581 acggtgcacg taaagggatg accgatacgg cccttaaaac agccgactca ggttacctta
    14641 ctcgtcgttt ggttgacgtt gcccaagatg ttatcattcg tgaggacgat tgtggcactg
    14701 atcgtggtct tcttatccgt gctattacag atggtaaaga agttaccgaa acgcttgaag
    14761 agcgtcttca aggtcgttac acacgtaaat cagtcaaaca ccctgaaact ggtgaagtct
    14821 tgattggtgc tgaccaatta atcactgaag acatggctcg taagattgtt gatgcaggtg
    14881 ttgaagaagt gaccattcgt tctgtcttta cctgtgcgac tcgtcatggt gtctgccgtc
    14941 actgttatgg tatcaacttg gcaactggtg atgctgttga agtgggtgaa gcagttggta
    15001 ctattgctgc ccaatctatc ggtgagcctg gtactcagct taccatgcgt accttccaca
    15061 cgggtggtgt agcctcaaat accgatatca cccagggtct tcctcgtatt caagagatct
    15121 ttgaagcacg taatcctaaa ggggaagcgg tcattactga agtgaaaggg aatgtcgtcg
    15181 agattgaaga agatgcgtca actcgtacca agaaagtcta cgttcaagga aaaactggca
    15241 tgggcgaata tgtcatacca tttacagcac gtatgaaagt tgaagttggc gacgaagtta
    15301 atcgcggagc tgcccttaca gaagggtcaa ttcaaccgaa acgtctcctt gaagtgcgtg
    15361 ataccttgtc agttgaaacg taccttcttg cagaagtaca aaaagtttac cgtagccaag
    15421 gggtagaaat cggagacaaa cacgttgagg taatggttcg ccaaatgctt cgtaaagttc
    15481 gtgtcatgga tccaggtgat acagacctcc ttccaggtac acttatggat atttctgatt
    15541 tcacagatgc taacaaagat attgttatct ctggtggtat tcctgcgaca tctcgtcctg
    15601 ttcttatggg tattactaag gcttcccttg aaaccaattc cttcttatca gctgcatcct
    15661 tccaagaaac aactcgtgtt cttacagatg ctgctatccg tggtaaaaaa gatcatcttc
    15721 ttggtcttaa agaaaatgtt atcattggta aaatcatccc agctggtact ggtatggctc
    15781 gttaccgtaa cattgaacca caagcgatga atgagattga agtgattgat catacagaag
    15841 tctcagcaga agccgttttt acagcagaag cagaataatc tcatgaaagg gtccttaggg
    15901 gctctttttt gtctgagttt gttggcagta aaaagcattg acaatcagtc ttagtcccaa
    15961 tgagcagatg tttttcaaaa tacttatgat ttagctataa taatgcataa gaggaatggg
    16021 taatgtgtta tgtatcaagt aattaaaatg tatggtgatt gggagccttg gtggttcatc
    16081 gatggatggc aagacgatat tatagatgag caacaattta gtgactggca agaagcgctt
    16141 gattatttta atcaagaatg gcagcgcatg aaagctattt ttcctagtta tcatagtcaa
    16201 aagaatttgt tagctacttt ttgggaaaaa gaagataaaa gatggtgcga ggactgtgac
    16261 gaagatttgc agcagtttca ttctctttta ctccttaaaa ataaagatat tgtaccaagc
    16321 aataattata tccctgaatt tgaacaacga aatgattcac cacaggtagc ttatctttgc
    16381 aagttaaacc tttaagtgtt tgttaaaaac aaaataagtt aaaagaaaat atcacttctt
    16441 ctgatatttt ctttttttgt ttacgaataa atgagtaagg aggaattatg gtacaagcat
    16501 tagcaaaagc tattctagca aaagctgaac aggttcatgc acaagatatt tatattttgc
    16561 caagagcaga tcaatatgat ctttttttac gaataggaga tgaaaggaga ttagttgatg
    16621 tttatcagag cgatcggatg gctcctctta ttagtcactt taaattcgtt gcaggaatga
    16681 tagttggtga aaagagacgt tgtcaggtgg gttcatgtga ttataagctt agtaaagata
    16741 agcagttatc tttgcgctta tctagcgtgg gtgattatcg cgggcaagaa agcttagtga
    16801 ttcgtctgct tcatcatcaa aataaaagtg tacattattg gtttgatgga ttgacaaaag
    16861 tagccaatca ggttggcggt agagggttgt atttatttgc aggaccagtt gggtctggga
    16921 agacaacctt gatgtaccag ctgatttcga attatcatca agaagcacag gttattagta
    16981 tagaagatcc tgtagaaatt aaaaatcacc aaattttaca attacaagtg aatgatgata
    17041 ttggtatgac ttatgacaat ttgatcaaac tgtctttacg ccatcgacca gatattttag
    17101 ttattggtga gattcgagat agtcaaacag caagagccgt tattagggct agtctaacag
    17161 gtgccatggt tttttcaacg gttcacgcta aaagtatctc gggtgtttat gcaagattgt
    17221 tagaacttgg tgtaacgaaa gcagaactgt ctaattgctt agcattaatt gcttaccaaa
    17281 ggttacttaa tggaggagca ttgattgact ctactcaaaa cgaatttgaa tattattcct
    17341 catcgaactg gaatcaacaa attgatcagc ttcttgaggc aggacatctc aatcccaagc
    17401 aagctaagct tgaaaaaatt atctagtaaa catcagcata aattcattca attactagct
    17461 aatcttttat ctacaggatt tagcttcgca gaggttattg cttttttaaa aagaagccag
    17521 ttgcttcagc tagattatgt tcttaaaatg gaagagtctt tattaaaagg acaaggctta
    17581 gcagatatgt tgtcgggttt aggtttttca gatgctattc ttactcaaat tagtttagct
    17641 gatagacacg gtaatattga aacaacatta gtagcgattc aacattactt gaaccaaatg
    17701 gcaaggatca gacgaaaaac tgttgaagtt atcacctatc ctcttattct tttacttttt
    17761 ctttttgtga tgatgctagg gttgagacgc tatttagtcc ctcaattaga aactcaaaat
    17821 cagataactt actttcttaa ccattttcct gccttcttta taggtttttg ctcaggtctt
    17881 attttgttgt tcgggatggt atggctacga tggcgatctc aaagccgctt gaaactctat
    17941 agtcggctaa gccgttatcc ttttttaggt aaactgttaa aacaatactt aactagttat
    18001 tatgctagag aatggggtac gttaataggt caaggtcttg atttgatgac tattttagac
    18061 attatggcca ttgagaaatc ctcactaatg aaagaattag ctgaggacat cagaatgagt
    18121 ctgcttgaag ggcaagcctt tcacattaaa gtagctacct accctttttt taaaaaagaa
    18181 ttaagtttaa tgattgaata cggtgaaatc aaatcgaaac tgggggctga gttggaaatc
    18241 tatgcccagg aaagctggga acaatttttt agtcagcttt atcaagtgac acaacttatt
    18301 caaccagcta tttttttagt agttgctgtg acaatcgtca tgatttatgc ggcaatccta
    18361 ttaccaattt accaaaatat gggaggtatt ttttaagatg attaatcaat ggaacaactt
    18421 acgacacaag aagctaaaag gatttactct tctagaaatg ttattggtga ttcttgtcat
    18481 cagtgttttg atgctattat ttgtgcctaa tttaagcaag caaaaagaca gggttacaga
    18541 aacaggtaat gccgctgttg ttaaattagt ggagaatcaa gcagaactat atgaattatc
    18601 tcaaggctca aaaccaagtt tgagccagtt aaaggcagat ggtagtatca ctgagaaaca
    18661 agaaaaagct tatcaagact attatgacaa acataaaaat gaaaaagccc gtcttagcaa
    18721 ttaaagcttt tactttgctt gaaactttac taagtttgtc agtgatgagt ttcattatat
    18781 tgggattgtc tgtaccagtg acaaaaagct atcaaaaagt agaagagcat ctgtttttta
    18841 gccattttga acatttgtat cgacatcagc aaaagttagc catattacag caaaaacagc
    18901 gcgtcttgga tatttcttca acaaaaattg ttacagaagg taatagccta acagttccta
    18961 aatcaataac agtgaatcat ccttatcggt tagttattga tcagatggga ggcaaccatt
    19021 ccttagctaa aattattttt gacatgactg atcgacgctt taaataccaa ttttatctag
    19081 ggagtgggaa ttatcaaaaa acaagtcaaa gcttacatag cccttgaaag tatgatcgca
    19141 acaggcatcc tctttagtat tgtcattctc gtcttaagca gtttacagca gagtcaggct
    19201 gctctaacgt actatcgaaa gcagcaagaa aagcttaatc tagccttgat ggcagtacaa
    19261 actagaacta aagagatgac attgaatggt tgtcatatta ctattttacg tacggataga
    19321 tacattagta ttcacgatga cgaaggagaa gtgatgaaga ttgagtaaac aattaagtaa
    19381 cataaaagct tttacccttc tagaggcgtt aatagcctta ctcgtgatat cagggtcttt
    19441 attggtttat caaggtttga cccgaaccct ccttaaacat agccattatc tagcccgtca
    19501 tgatcaagat aattggctct tattttctca tcaattgcga gaggagttaa gtggagcaag
    19561 gttttacaaa gtagctgata ataaactata cgttgaaaaa ggaaagaaag tactagcttt
    19621 tggccaattt aaaagtcatg attttcgaaa atcagctagt aatggaaaag ggtatcaacc
    19681 catgttattt ggaatatcac gtagtcatat tcacatagag cagtcacaga tttgcattac
    19741 tttaaagtgg aaaagtgggt tagaaaggac tttttattat gcctttcaag actaatctca
    19801 aagcaggcat ccttttgtat gctatgttta tggctagtat ttttttgctg gttttacagg
    19861 tttacctttc tcaagtgaca gctctacaca aggaatacca agctcaaact gactatgtta
    19921 aagcccgact gatagcagaa atagtttatc aagatcatag atataaagct tctaatcctg
    19981 tcttttttaa aggtggtcaa gtcatttgtc gagagcgaaa agagagatgg atgttaattg
    20041 ttaagttaga tcagcaacga cagtatcagt ttgaatacct taaacccaaa caatatagtc
    20101 aataaatagt attgttgtca taaatcctta aaatgatcca atatatagta attaaaggtg
    20161 acacttcttt tcatttcaag tgtaatttgg tatgataagg ttatgacttt tgaaaaaatt
    20221 gaagaagctt atcagctgct cttagagaac tgtcaactaa ttgaaaatga tctaaaaaca
    20281 catatatacg atgccattgt tgaacaaaac tccttttatt taggggctga gggagctagt
    20341 cctcaagttg ctcaaaatag tgataaactg aaagccttgt gcctgacaaa agaagaatgg
    20401 cgtaaggcct accagtttct ttttattaag gcagctcaga ctgagcaact ccaagccaac
    20461 catcagttca caccagatgc tattggcttc attctgctgt atcttttgga acaattgagt
    20521 gataaagata gcttagaggt acttgagatt ggaagtggaa cagggaacct agcccaaacc
    20581 cttctcaaca acacgagcaa gagccttgat tatgtaggga ttgaacttga tgatctcttg
    20641 attgatctgt cagccagtat tgctgagata atggattctt cagctcattt tattcaagaa
    20701 gatgcggtaa ggcctcaatt actaaaagaa agtgacattg tcatcagtga cttaccagtt
    20761 ggttattatc ctaacgatga tattgccaaa cggtacaagg tggctagttc agataagcat
    20821 acctatgccc atcatttatt aatggaacag tctttaaaat acttgaaaaa agacggtttt
    20881 gcgatttttc tggcaccagt caatttattg acgagccctc agagccagtt gttgaaacag
    20941 tggttaaaag attatgctca ggtggtgacc ttgattacgc taccagattc tatttttggt
    21001 catccctcaa atgccaagtc cattattgtc ttacaaaaac aaacagacca cccaatggaa
    21061 acctttgtct atccaattcg ggatttgaag cttgcagaga atattcatga ttttatggaa
    21121 aatttcaaaa aatggaaact gagtaatgtc aattaattga ttttttgtta taataaaaaa
    21181 gcatcacaga aaacgatttc aagagaggtt aaaaatgtca aagacaattg caattaatgc
    21241 aggtagttct agtttaaaat ggcaacttta tcagatgcca gaagaagcag tgttagcaca
    21301 aggaattatt gagcgtatcg gtctcaagga ttctatttca acagttaagt acgatggcaa
    21361 aaaagaagag caaattcttg atattcacga tcatacagaa gctgttaaaa tcttattgaa
    21421 cgatttgatt cactttggaa tcattgcagc ttatgatgaa attacaggag ttggacaccg
    21481 tgttgttgct ggtggtgaac ttttcaaaga atccgttgtg gttaatgaca aagttcttga
    21541 acagattgaa gaattatccg ttttagctcc acttcacaat cctggagcgg cggcagggat
    21601 tcgtgccttc cgtgatattt tgccagatat taccagtgtt tgtgtgtttg acacgtcatt
    21661 tcacactagc atggcaaagc atacttacct ttacccaatt cctcaaaaat attatacgga
    21721 ctacaaggtt cgtaaatatg gggcgcatgg gacaagtcat aaatatgtag cgcaagaagc
    21781 tgctaaaatg cttggtcgtc cattagaaga attaaaacta attactgctc atattggaaa
    21841 tggtgtctca attacagcta attaccacgg taaatcagtt gatacctcga tgggctttac
    21901 accacttgct ggtcctatga tgggaacacg ttctggtgac attgacccag ctatcattcc
    21961 ttatttaatt gagcaagacc cagagttaaa agacgctgct gacgttgtta atatgttaaa
    22021 caaaaaatca ggtcttagtg gggtgtcagg catttctagt gatatgcgtg atatcgaggc
    22081 tggtttacaa gaagataatc cagatgctgt tttagcttac aatatcttta ttgatcgcat
    22141 taaaaaatgc attggtcaat attttgctgt tttgaatgga gcagatgctt tggtctttac
    22201 agctggtatg ggtgaaaatg caccattgat gcgtcaagat gttattggtg gcttaacatg
    22261 gttcggaatg gacattgatc ctgagaaaaa tgtttttgga taccgtggtg acatttcaac
    22321 tcctgagtca aaagtgaagg tgcttgttat ctcaacagac gaagaattgt gcatcgcgcg
    22381 tgacgttgaa cgtttaaaaa atacaaaata aaagagacta agtctcaata gattaaccaa
    22441 gtaaggtaac actttacttg gttttttatg aggtttatct gttggttatg gtgcctaggt
    22501 attagttctg atcagtctcc ttgctttttg taatcttgtg ctaggcgatt tggatgtcag
    22561 ccttatttag aagtttttaa ttgcttcaac gcttttcttg tatgtgttta tagagcccaa
    22621 tgatctaaaa gactatttga taacggttta tgatgagcgt aatcgtgcga ttcgaaaaca
    22681 gacacaagtt tactgctttt acctgatgat tgttctattt gttgccttat tctttttctt
    22741 cccttgctta accattcgag atcttgtttc ttataagcta cctttgattt ttgcttacct
    22801 ttacttgatt atcagaagtc tggtggctaa gaaaatggag gcactaggga aaataacaac
    22861 taatagtcaa aaacctccgt ttgatacgag tcaggttctt tgttagatga cttgtctaac
    22921 ggttgagttt cctgtctggt caacggaggt gtttgtattg ttgtctgatt tgtattgggg
    22981 cacttatttt acaagctttt agctttatcg atggttttgt caatggcaga gctgacagta
    23041 gctgtgaggc caaggcgttc taactccatc agaccagcaa tagttgtgcc accggggcta
    23101 caaatagcgt caatgaaatc gtgcggactt tgagaactgg tcttgagatt gctggcgcta
    23161 gccaatactg tttgagtaac aatctccagc gcctttgctt taggtatgcc attcttgacg
    23221 ccagccttag ccaaagcctc aataaagaga taaatatagg caggacttga ccctgctaaa
    23281 gcggtaaagg tgtcaaaatc cttttcacta atatcaaatg tgctaccaaa gctatctgtt
    23341 aagtctcgaa cacgtgcttg taattcctgg gacaccaaag catttcccgt taaagcggta
    23401 ctgctttgga gaatttgtgc attcatgttt ggcatgatac gtagcagcgg aaggtcttgt
    23461 cctacgaatg ttgctagtcg ttgaagggaa atgcctgctg ccatagatat aataggctgt
    23521 ttgaagtgaa gcggtttgag taccgtttca aatagttgag gcttgatgcc taaaataaca
    23581 agatcaacct ggtcaataag gtcttggtgg gacatagcat aaggcagtgc taactgctcc
    23641 gcaatttcct tggaccgttc taaagatgat cctgaaatga taagttcatg gggtgtttgt
    23701 ttaaggcctt tgatgatagc gctagccatt ttgccaacac caataatgcc aattttcatt
    23761 ctgttgctcc ttgtgggata ttatggttaa tcaggctaat gctagtttag taacatttaa
    23821 tcaagtcaac ggttgagcga tccagttttt tgataatggc ttgtaagaag gcttgggctt
    23881 ctacgaaatc atccatagcg tagagggttt gatgagagtg aatgtagcgt gcacagactc
    23941 cgatggttgt tgatgggaca ccaccatttt gaaggtgtgc agcacctgca tctgtgcctc
    24001 ccttgccaca atagtattgg aaattgacac cagcttcctc agcagtagtc agtaagaagt
    24061 cgcgcatatc tttgagcatg acatggcctg ggtcgtagaa acgcaacaag gtaccatctc
    24121 cgattgttcc aggattgcca taaatatcac cagcaggcga acaatctact gcgaaaaaga
    24181 gttcagggtc gaacttggtg gttgagacgt gggctccgcg cagaccaact tcttcttgaa
    24241 cgttagcacc tgcaattagg gtgttgttaa ggtcttgtcc ttttaacgct tcaagcattt
    24301 ctgttatcat gagaacgcca tagcgattgt cccaagcttt tgaaataata tttttttgat
    24361 tggctgttag gattgtttca gattgaggga taataatatc acccggtgta ataccaaatc
    24421 tttcagcttc tgccttatcc gtaaagccac catcaaacac aatatcttcg atatgtggta
    24481 gactagcaga gccatttgcc ccacgtaaaa aatggggagg taccgatcct gaaataaggg
    24541 gaataacttg gccagtgcgt gtgtaaaggg taaaccgttg tgaactgaca acaagtgggt
    24601 tccaaccacc gataccaacc acgcgtagcg ttccgtcaac tttgatatca ctgaccataa
    24661 aaccgacttc gtccatgtgc gcagctacta aaatacgggg ggctttttca gctttactat
    24721 ctctgatacc aaaaatgcca ccaagcccgt ctgtttcaac acggtcaacc agcggggtta
    24781 ttttggtgcg taggtagtca cgaacgctat gttcatagcc cgcaatgcca tccagttcgg
    24841 taacttcttt gatttttgag aataagtctg tcatttttca tctccattta aaaggtttca
    24901 gaccagttca acgcggtcat ctccttatat tctaccactt tttaagtaag aatgggtttc
    24961 acagaaaaga aaaatcccag agactagaga tctctggaag aagtgtttgt cttttggcga
    25021 taacctgttt ttttaggcag caaggaaatc attaaaatga taaagcacaa gctggttaat
    25081 aagaatagta gggcgcttag gatgcgaaaa gactcttcac tagcgaaaag taaggataat
    25141 ggagtcataa ggagaacctt ccattttagg ttaatcagtg atttttatag cgtggttaaa
    25201 ttaataataa accacaccta atcaacgtac ctttagttta gttgttttta ctatttttgt
    25261 caatacataa cagtagaaat ctttagtttt cttatttcag atcgtccaat ttgatctttt
    25321 tatgataaaa tgagggatat gagtaaaaag aaaataggta tgatttcagg tatctttgga
    25381 tttagtttag ctattggcct aggaatagtt atcaaagatt attgccaaga caggcagcgt
    25441 cgacaaatga caagggattt acgcaccttt ttttcacctt taggacaaat cgaagtttta
    25501 tatatcaatc cttgtcaggt caaacaagat tatatttcag gtggggttgt tatgtcaaac
    25561 ggcaaacagt accaattcac ctatcacagt cgacaaatta gttttgagga ggacaaggga
    25621 tgatcagacc gacttcttat gagtcattag cgactcttat tgaaaaagaa gataagctgg
    25681 tgttattttt tacggcagac tggtgtccag actgtcaatt tatttatcct attatgccag
    25741 aaattgaagc agaacttaca gatatgactt ttgtttgtgt taatcgtgat cagtttatag
    25801 aggtagcaca aaagtggaat atttttggta ttcctagttt tgtcgtgatt gaaaaaggtc
    25861 aggaagtagg gcgtctggtt aacaaaatga gaaagacaaa aactgagatt atgcattttt
    25921 tagctgctta tcaataagaa aagaggaaga ataaatgatt tttgcataca ataaagaaca
    25981 agttggcgat gtcttgatgg ttatcttaca agacaccaaa gatatcaaac gtcaagtaga
    26041 acgaaaaggc aaagtagccc gtgtttttgc agaagaaagc ggcaaaaccc ttgcttggaa
    26101 tatctttgaa gcgtcaagct tgattactat tgaaggcaat ggacagattt ttttgacaga
    26161 cgagaacctt gcaagattaa atgcagagct tgctaaggaa ggattttcag aaaggcttga
    26221 accgattgtg ggacctgttt ttgtggttgg tcaaattgtt gagatggtgg ctcatccaga
    26281 tagcgaccat cttaatatct gccaagtggc tattggtgaa gatcaaacgg ttcaaatcgt
    26341 agcgggcgca ccaaatgctg cacttggttt aaaaacgatt gttgccttac caggtgctat
    26401 aatgccaaat ggtagtctga ttttcccagg aaaattgcgt ggtgaagaaa gttatggtat
    26461 gatgtgctct cctcgtgagt tagccttgcc aaatgcaccg caaaaacgtg gcattattga
    26521 atttgatgag tcagctgtgg taggagaagc ttttgaccca gccaaacatt ggaaaggtta
    26581 gaaaaaccag ctgaaataag actgtattta actaaatgac cagaaaaaaa ggattaggag
    26641 cccttaatcc ttttttctta tgttttcaaa aacgtttaaa atgaaactta ttttaccaca
    26701 atttttacga ataataagat aaggaggtca gtatgtataa taaagtgata gcaatcggtc
    26761 gtttggtagc taaaccagaa ttggtaaaaa cagctacgga taagcatgta gcacgtctct
    26821 ctttagctgt taatcgaaga tttaaaaatg cttctggaga gcgagaagct gattttattt
    26881 cagttgttgt ttggggaaag ttagcagaaa ctctggtttc ttatgctagc aaaggtagtt
    26941 tgatgtctat tgatggcgaa cttaggaccc gcaagtatga taaagatggg caagtgcatt
    27001 atgtgacaga agttctctgc caatcatttc aactgcttga aagtcgtgct cagcgcgcta
    27061 tgagagaaaa taatgttact aatgatctag ttgatttagt cttagaagaa gatactcttc
    27121 ccttttgata gaggataatg cttctcatca gggttcagct gattactgaa atatatgatg
    27181 aggtgatatc cgaacaacaa aagtgtgact agatacttct gataaaaata aaaaaacacc
    27241 ttacgagtat gaacaaagtt tcaagtgcta gatgttggaa ctttgttcat cataggaata
    27301 gtagggtgtt ttttagtgta ttacttcttt ttgttgctag tgttaaggtt tacttgctta
    27361 caagcggtta tcaggccact agaactctta taataaatgg agctctttga gtttggtgtc
    27421 aatcattttt aagacagtcg ccaaatcttg tgggttttga acgaagtcaa gggaattgcc
    27481 atcaattttc atttttggag agacctcgta gtcttcgtac caggttgggt attcaccgtg
    27541 gacttgatgg taatattgct caagactagg attgccgtcg acctgctcaa aacttcggcc
    27601 acgtctttca atgcgctcaa gcattttgtc aaaagacaca tcaatgtaga tgagaagatc
    27661 agggcgtttt ttaggcatgc cttctagttc ttctaacatg ttggcgagaa gttcctgata
    27721 gatgtcaagt tctgtcttag tgacattgcc atttttgtag ttaagtttta agaagagttc
    27781 gtcttcaaaa atagagcggt caagaatgtt gttatcggct tgataagctt ctttgatgga
    27841 cttaaatcgt ttattcaaaa aataaatttg aagtaaaaag gcgtattttt tagggtcttg
    27901 gtagtagagg tctagcacgg ggttattatc aacagcttcg taaaaaacgt cagttcctaa
    27961 atgctctcca agtgcagcag caagcgagct cttgccagcc ccaattgttc cagctagtac
    28021 aatcaacatg cgtctccttc taatatcatt agcgtactgt ttcgaagatg gcttcaacct
    28081 cagctagagt ctcagcgcgt gaaacagcac cacgaacttt ggcagcacct gctgttccgc
    28141 gaagatagtg tggtgctaag ccccgaaatt cccgaacagc aatggtttca cctttgaggt
    28201 taatcaggcg tttaaggtgg tctttggcga tgtctaattt tttggcaaag ggaagatctg
    28261 gcaattcttg accagtttca aagaaatgat tgatttgggt aaaaagataa ggattgttca
    28321 tggctgcgcg gccaatcatc acggcatcta caccgatttc ttcaatcata aatttggcgt
    28381 cttgcaccga acgcacgtcc ccatttccaa taaagggaat cttagtgata gccttagaaa
    28441 ctcgggctaa tgtctcatgg tcgcaggttc ctgtatacat ttgttcacgg gtacgaccgt
    28501 gcatggcaag agcagataca cctgccgact cagcggcaag ggcattttca acagcaagtg
    28561 aactatccgc ccaacctgta cgcattttga cagtcagtgg aatatctaaa acagacgtga
    28621 cttccttgac aatgtggtaa atcttatcag ggtcacggag ccacttggca ccagcctcgt
    28681 ttttgacaac tttattaaca gggcagccca tattaatatc aacaatatcg gccttggtat
    28741 tggtttgaat gaaatcagct gcacgtttca acccttctgc gtcaccacca aataattgaa
    28801 tggacatagg gtgctcattt tcatcaatat ggagcatgtg aagggtcttt tcattgttgt
    28861 aaagaagccc tttttcggaa atcatttcca taaccaccaa accagcacca aattctttgg
    28921 cgatggtacg aaaggcagaa ttggtcacgc cagccatggg agcaaggaca gtgcggtgag
    28981 ggatttccac atcaccaatc ctaaaggaag aattaagctt tatcactgat aatggcctcc
    29041 aaatcacttt cattaaattg gtacttggta ccacaaaatt ggcaaacaat ctcagcaccc
    29101 ttatcttcgt caatcatggc ctgtaaatct gcttttggca aagtcattag ggctgcttca
    29161 aaacgttctc tagaacagtc acactgaaaa ctcagaggtt cttcagaaag acgcttgtaa
    29221 ggttcatctc catagatggc ctccaaaagg gcatccacat gatttttgga agctagtagg
    29281 tgagaaatgg caggcatttc ttgcaggcgt ttttcatagc gagcaatctc ttcttcagaa
    29341 gcgcctggta gcacctgcac cataaagcca ccagcaacct taaccttatc attttcatct
    29401 aaaagcacat taagtccgat tgcagatggt gtttgctctg attcggttaa gtagtaggca
    29461 aaatcctcac caatttcccc agtaataaga ggcgttgttg aggtgtaagg gttacctgtg
    29521 ccataatcaa taatcgtcac aaaatgacca ttccccataa aaggcccaac aaggacttca
    29581 cctgttgcgg tctttttaat atcgacacca gtattttgaa tgtaaccttt cacatgtcct
    29641 ttggtatctg ccacagagat aatgtgtcca aaagaagaat caccaatcac tttgacggtg
    29701 attttactat cgcctttttg attagccgcc aaaatctggt tggcgatcaa ggtacggcca
    29761 agcgcaacag tagacgatga cagcgtgttg tgtttttctt gagctaatgc aaccgtctca
    29821 gtgctatcaa ggacataagc cctaaaagcc cctgattgtg ctattgattt aattatttta
    29881 tccataactt agattatagc ataaagtgta aaacttgtat tgacaggatt gcttgaaaaa
    29941 tcaatacaga tagacagtaa aaaatcccag agaatgactc gggattaagt taaggtgtgg
    30001 tctaaagtcg cgcaatgtgg tgacatggcg cttatgttaa ttgcttggtt aaatcagctt
    30061 ggaatttttc ctctttaact tgatacatca attcttggat agacagaatc gattcatcaa
    30121 aagatatttc agcaacagca attccttttg taagttcatg gtgaacaaaa ggaatcagtt
    30181 gactgtgagt gatgaccaaa tctggcttta aatcaggaat ttgataaaca ttatcttgca
    30241 atagataata ggaatgaaaa tcaatgcttt tatccgagaa ataccttgga aaagaatccg
    30301 ttaggagatg agcattgata aaattactgg ctacgaaaac aacaactaaa ggaggttgga
    30361 tatttcttag actttgctcg acatagtggc aaaaaagatg aaaatgctta tggttcaagt
    30421 cacgcttacc aggaagtttg gccatccact cttcgacaat taactttaag gacgtataga
    30481 gtttttggtt tcctttatag tacggagaaa cgaataagtt ggtctcagga ataaaatgtt
    30541 gcagattaaa caagaatgat tttgaaaaaa acataagagc ttttactaaa ctagcctttt
    30601 gctcttttag gttaggtaaa agagtgatga taggatttaa aagcaggcga aaagtatcat
    30661 tttcttcaaa aagttgacaa tattgtctga tatgctcagg tgtccattgt aagctcgcaa
    30721 aagaattatt agcggtgata taaattaaat agaggtagtc caaatctcct gctgaaaagt
    30781 ttagttggca gtaagtttcg ataatatcat ggctactttt tttcaaagaa tcgtagacaa
    30841 aaagtttttt taattgttga aaaattctgg tttggggaat agttaccgaa aattgatgcc
    30901 gcttccacga taaagctaat aaaatgtcat agaaagaaaa cgattccgat aaccaaggag
    30961 aggttttaag gtgggtggaa ctatgggata aaaagctatg aatagtgttt ttgtcttgct
    31021 gcgtcaagtc ataaacttta atgccaaact tactatatag cagagcgatg aggtaacgga
    31081 tgcgatattc ctcaccgaca atcttgttct tagagagttt taattcaaag tttcttaata
    31141 aaggaatcaa tgcttcgcgc atccgataag ctgaggagtt tgataaaaaa tgacttcttg
    31201 caaaatccgt aaggggacga gagtgggaac cattttttat taaaaaggct agtaattgta
    31261 agacattaga tgatgcatag agttggtaaa gataagtttc tttaaaagga tgtgtaaatt
    31321 ggcaagatat catccttttt tggatggtca tagacagact accagggaaa aaggcattca
    31381 gttcctcaca ataatggttt agttgtaaaa aggttaagcc agttttttct gctacctcag
    31441 ttattggcaa ataagatgtc ttaaaaaaca agacaattaa ctgacatttt gattcgattg
    31501 atgattccaa gtatttttct atcaaggaaa gggacctctc ttcctacact tagaaagcca
    31561 aataagtctt tgataagtgt attctcctat ttcaattcta tctaagctaa aaatagaagt
    31621 caaatctaat ggtttttggt aaaaagtcga aaccttttga aatagcttta aagcaatatt
    31681 ttctcaaaaa atcattttca aaaacactaa tttggtgaaa aacttagtac gaatatattt
    31741 ctttgacttc aatagaatga tatgatgtca cattgagagg agagaaaatg aaaaaaacaa
    31801 ggtttccaaa taagcttaat actcttaata ctcaaagggt attaagtaaa aactcaaaac
    31861 gatttactgt cactttagtg ggagtctttt taatgatctt cgctttggta acttccatgg
    31921 ttggtgctaa gactgttttt ggtttagtag aatcctcgac gccaaacgca ataaatccag
    31981 attcaagttc ggaatacaga tggtatggat atgaatctta tgtaagaggg catccatatt
    32041 ataaacagtt tagagtagca cacgatttaa gggttaactt agaaggaagt agaagttatc
    32101 aagtttattg ctttaattta aagaaagcat ttcctctcgg atcagatagt agtgttaaaa
    32161 agtggtataa aaaacatgat ggaatctcta caaaatttga agattatgcg ataagcccta
    32221 gaattacggg agatgagcta aatcagaagt tacgagctgt tatgtataat ggacatccac
    32281 aaaatgccaa tggtattatg gaaggcttgg aacccttgaa tgctatcaga gttacacaag
    32341 aggcggtatg gtactattct gataatgctc ctatttctaa tccagatgaa agttttaaaa
    32401 gggagtcaga aagtaacttg gttagtactt ctcaattatc tttgatgcgt caagctttga
    32461 agcaactgat tgatccgaat ttggcaacta aaatgccaaa acaagttccg gatgattttc
    32521 agctaagtat ttttgagtct gaggacaagg gagataaata taataaagga taccaaaatc
    32581 ttttgagtgg tggtttagtt cctactaaac caccaactcc aggagaccca ccaatgcctc
    32641 caaatcaacc tcaaacgact tcagtactta ttagaaagta tgctataggt gattactcta
    32701 aattgcttga aggtgcaaca ttacagttga caggggataa cgtgaatagt tttcaagcga
    32761 gagtgtttag cagtaatgat attggagaaa gaattgaact atcagatgga acttatactt
    32821 taactgaatt gaattctcca gctggttata gtatcgcaga gccaatcact tttaaggttg
    32881 aagctggcaa agtgtatact attattgatg gaaaacagat tgaaaatccc aataaagaga
    32941 tagtagagcc ttactcagta gaagcatata atgattttga agaatttagc gttttaacta
    33001 cacaaaacta tgcaaaattt tattatgcaa aaaataaaaa tggaagttca caggttgtct
    33061 attgctttaa tgcagatcta aaatctccac cagactctga agatggtggg aaaacaatga
    33121 ctccagactt tacaacagga gaagtaaaat acactcatat tgcaggtcgt gacctcttta
    33181 aatatactgt gaaaccaaga gataccgatc ctgacacttt cttaaaacat atcaaaaaag
    33241 taattgagaa gggttacagg gaaaaaggac aagctattga gtatagtggt ctaactgaga
    33301 cacaattgcg tgcggctact cagttagcaa tatattattt cactgatagt gctgaattag
    33361 ataaggataa actaaaagac tatcatggtt ttggagacat gaatgatagt actttagcag
    33421 ttgctaaaat ccttgtagaa tacgctcaag atagtaatcc tccacagcta actgaccttg
    33481 atttctttat tccgaataac aataaatatc aatcccttat tggaactcag tggcatccag
    33541 aagatttagt tgatattatt cgtatggaag ataaaaaaga agttatacct gtaactcata
    33601 atttaacatt gagaaaaacg gtgactggtt tagctggtga cagaactaaa gatttccatt
    33661 ttgaaattga attaaaaaat aataagcaag aattgctttc tcaaactgtt aaaacagata
    33721 aaacaaacct cgaatttaaa gatggtaaag caaccattaa tttaaaacat ggggaaagtt
    33781 taacacttca aggtttacca gaaggttatt cttaccttgt caaagaaaca gattctgaag
    33841 gctataaggt taaagttaat agccaagaag tagcaaatgc tacagtttca aaaacaggaa
    33901 taacaagtga tgagacactt gcttttgaaa ataataaaga gcctgttgtt cctacaggag
    33961 ttgatcaaaa gatcaatggc tatctagctt tgatagttat cgctggtatc agtttgggga
    34021 tctggggaat tcacacgata aggataagaa aacatgacta gagctgattt cagaacttct
    34081 aattcatctg gagaacttaa caaactatca ttttcagata aagaagcaat aaagccctta
    34141 ctcataggac ttgttaaaaa aatagccctt attcttattg gcggctatct actttttcac
    34201 tttgtttttg gatttatgat tatcaaaaga aacgatatgg ctcctagtgt aaaagcagga
    34261 gatgctattt tattttatcg cttatctcag acttataaag tagaagaagc agttgtttat
    34321 gaggactcta aaacatctat aacgaaagtc ggtcggatta ttgctcaagc aggtgatgaa
    34381 gtggacctga cagaacaagg tgaattaaaa attaatggcc atattcaaaa tgaaggacta
    34441 acttttataa aatcaagaga agctaattat ccgtatcgaa ttgctgataa tagttatttg
    34501 atactcaatg attactatag ccaagagagt gagaattacc tacaagatgc aattgctaaa
    34561 gatgctataa aaggcacgat taatacactt attcgattaa gaaaccatta agctaaaggc
    34621 ttatttaaaa aaggagagaa acaatgaaat tacgtcactt actattaacg ggagcagccc
    34681 taactagttt tgctgctaca acagttcacg gggagactgt tgtaaacgga gccaaactaa
    34741 cagttacaaa aaaccttgat ttagttaata gcaatgcatt aattccaaat acagatttta
    34801 catttaaaat cgaacctgat actactgtca acgaagacgg aaataagttt aaaggtgtag
    34861 ctttgaacac accgatgact aaagtcactt acaccaattc agataaaggt ggatcaaata
    34921 cgaaaactgc agaatttgat ttttcagaag ttacttttga aaaaccaggt gtttattatt
    34981 acaaagtaac tgaggagaag atagataaag ttcctggtgt ttcttatgat acaacatctt
    35041 acactgttca agttcatgtc ttgtggaatg aagagcaaca aaaaccagta gctacttata
    35101 ttgttggtta taaagaaggt agtaaggtgc caattcagtt caaaaatagc ttagattcta
    35161 ctacattaac ggtgaagaaa aaagtttcag gtaccggtgg agatcgctct aaagatttta
    35221 attttggtct gactttaaaa gcaaatcagt attataaggc gtcagaaaaa gtcatgattg
    35281 agaagacaac taaaggtggt caagctcctg ttcaaacaga ggctagtata gatcaactct
    35341 atcattttac cttgaaagat ggtgaatcaa tcaaagtcac aaatcttcca gtaggtgtgg
    35401 attatgttgt cactgaagac gattacaaat cagaaaaata tacaaccaac gtggaagtta
    35461 gtcctcaaga tggagctgta aaaaatatcg caggtaattc aactgaacaa gagacatcta
    35521 ctgataaaga tatgaccatt acttttacaa ataaaaaaga ctttgaagtg ccaacaggag
    35581 tagcaatgac tgtggcacca tatattgctt taggaattgt agcagttggt ggagctcttt
    35641 actttgttaa aaagaaaaat gcttaaatta ttattatgat agtaagactg attaagctcc
    35701 ttgacaagtt gataaacgtc attgttcttt gtttcttctt tctttgttta ttgattgcgg
    35761 cacttggaat ctacgatgct ttaacagttt atcaaggagc taatgctact aactatcaac
    35821 aatataagaa aaagggtgtt cagtttgacg atttattagc tattaattct gatgttatgg
    35881 catggctgac tgttaaagga acgcatattg attatccaat tgtacaggga gagaataatt
    35941 tagaatatat caacaaatca gtagaaggag agtactcctt atcaggaagt gtttttctag
    36001 attatcgtaa taaagtaact tttgaagata aatactcatt aatctatgca catcatatgg
    36061 ctggaaatgt tatgtttggc gaattaccta actttaggaa aaaatcattt tttaataaac
    36121 acaaagaatt tagtattgaa accaaaacaa agcaaaaact gaaaatcaat atttttgcat
    36181 gtatccaaac agatgctttt gacagtttac tgtttaatcc aattgatgtt gatatttcta
    36241 gtaaaaatga atttttaaac catatcaagc aaaaatcggt acagtatcgt gaaatattga
    36301 caacaaatga aagtcgtttt gttgccttat caacctgtga ggatatgaca acagatggta
    36361 ggattatcgt tattggacaa attgaataat tgtaagagaa aggaggtcat atgaaaaaat
    36421 ctatattaag aattttagct attggttatt tacttatgag tttttgtttg ttagactccg
    36481 tagaggcaga gaacctcact gcaagcatta atattgaagt tattaatcaa gttgatgttg
    36541 ctaccaacaa acaatcctct gacatagatg aaacgtttat gtttgtaatt gaagcgttag
    36601 ataaagaaag tcctttacct aattcggtaa ctacttctgt taagggaaat gggaaaacat
    36661 catttgaaca gttgactttt tcagaagttg gacaatatca ttataaaatt catcaactgt
    36721 taggtaagaa tagtcaatat cattatgatg aaacagtata tgaagttgtt atttacgtat
    36781 tgtataatga gcaaagtggt gctttagaaa ctaacctagt ttctaacaaa cttggagaaa
    36841 ccgaaaaatc ggagcttatt tttaaacaag aatatagtga aaaaacaccg gaacctcatc
    36901 aaccagatac aactgagaag gaaaaacctc agaaaaaacg taatggtatt ttgccatcaa
    36961 ctggtgaaat ggtgagttac gtatctgctt taggaattgt cttagtggct accattactt
    37021 tgtattctat ttataaaaag ctaaagacaa gcaaatagat tcaattttaa gcagagtaat
    37081 tctccttgag gatttaggaa agatatgtaa gaaaaaccaa aaattccttt acttaatgat
    37141 aaaggaattt tttattgccc cacgacagca aattgttcgt aagcgtccaa taacaaggta
    37201 tattgaaaac ctccaaagtt tctaattgac tctggaggtt ttgattattg acaatttgtt
    37261 tgtacttttt tagcccatgg caaataagct tctagcactt ctcttttagc gagagtttct
    37321 tcattaggaa ggcggtctag aaggtagcta atatattttt cggagttcag tccatgtcgc
    37381 ttagccgttt caagcaaact catgatgata gctgccgctt tggctccttc aaaactttga
    37441 gaaaacaacc aattttttcg gcccatcact aaggatttga tagctctctc tgccatattg
    37501 ttagacagaa caatatggcc atcctctaaa acagttctaa aggttctttc atgcttgaga
    37561 ctataagcga tagcgagacc cagcttcgat cctgaaagga caacttgctc gcgacaccaa
    37621 tcaaagaagg tggtcattaa tggcgtcaag atttctttgc gtttaaccag acgctcttga
    37681 gggggtaact cacaccattc agcttctaag gcgaacaact tgtcacagta aacaagtcct
    37741 ttacgcccta gagaagtctt atcagcttgc ttcggggtgg cctcaaagaa cttccgcctc
    37801 acatgtgccc aacaaccaac aagcttggca tgctctaatt gacgataagc cccatgcata
    37861 tcacaatgca cataacctga gtaatcgccg agaacctctt gagtaacgag gccgctacgc
    37921 cttttatcat gatggtaaag ggtaatccct tttttctcat gcttaccaga caaaaaagtc
    37981 cagtaatagg tcaactgagt gtcactttca agaactctat aagatgtctc atccgcatga
    38041 atgacctctt gacttaataa gatgtcacga agcaagtcat aaagaggctc aaaataatac
    38101 tggctagact tgatatgcca gttagcgatt tccttgcgac taatggacag tcctaattta
    38161 ttccaatcct cttcctgtct gtagttagga actttaaggg tgaatttttg atgaacggta
    38221 tgggcaataa tagaagccga accaaggcta tgagctaatg gtgccttagg aacaggcgct
    38281 ttgatgatct tgtcactgag gctattatcg ctacaagttt ggcacttata agcgtgttgc
    38341 acatgattta tacgtttcaa ttgtgctggg ataaagacta attcttgacg ttgaaccacc
    38401 gagccaattt ctgtcaatgt tccatgacaa tccggacaag tacagctgtc accaattaat
    38461 tcgtggtgaa caagctcagg ttcaaattga gctagaatag cttgacgtct tcctttgatt
    38521 ttcttgcgtc tataagtaat gtcttctgtt tctactgggc aagtcatccg cttcttctgg
    38581 taattggtcc tggtcaaaga gactgagttg accggtcata ggcatagctt tttcagaaga
    38641 tttcccataa agcttttgag ttaaataagc cacttgttca cgcaggaggg ctagctcatt
    38701 agccattgtt tcaatggttt tggcttgtgt tttaatgact ttatcttgtg aactcatggt
    38761 cttcctcctg atattttctt cattatacct gaagaaaagc catgagttca atagaaatca
    38821 tgactttttg aaatttttat gttaggacta atgaaaaatc ccttcataag ccagtccacc
    38881 tgtacagctg tcaagcattt gacctcatcc ctatttcttg gccaggctag tttcccattt
    38941 tcaaagcgtt tataaagtaa ccagaaacct tgaccatccc agtaaagcgc tttgaaccga
    39001 tcacgtcgcc caccacagaa gagataaaca gcacctgaaa agagatctaa ctcatgttgg
    39061 gatttgacaa gataggctag ggaatcaatg ccttgtcgca tatctgtttt tccacaaacc
    39121 agataaactt gtcctaggtc atttagccga atggtcatcg ttcagtacct tatccaaaat
    39181 gctttccaac aagtcctgat tgagtgcttg aaataaacta agttccagtt ttccaaggcg
    39241 aactttaagc aagatatcat ttctgttttt ttctcaaatc gacgagattg gggaacttcc
    39301 aaaggaacaa tagggtgtga tatttaaatt atcctccgat agactagttt tactaacagt
    39361 atactggagg attgagaatc acggtagata ccctgttatt ggacgcttac attattttta
    39421 ttgggaacag ccatttttct ttaccctacg ttaagtagtc agtggaatgc tatcgtgatc
    39481 gtcaattgtt atcaacttat cacaaacaag tgactcaaaa gaagccctca gaaatggagg
    39541 aggtgtggca aaaggctaag gcgtataacg ctaggcttgg gattcagcct gttccagatg
    39601 ctttttcatt tagggatggc attcatgata aaaactacga aagcctactt caaattgaaa
    39661 acaatgatat tatgggatat gttgaagtgc cctctattaa agtgacgtta cccatatacc
    39721 actatacgac agacgaggtg ctaactaaag gagcaggtca cttatttgga agtgccttac
    39781 cagttggtgg tgacgggact cacacggtta tttctgctca tagaggcctt ccatcggcag
    39841 aaatgtttac taatttgaat ttagtgaaaa agggagatac tttttacttt cgtgtgttaa
    39901 ataaagtatt ggcttataaa gttgatcaga tactaactgt tgaaccagat caagtcacat
    39961 cactttctgg agtcatgggg aaagattatg ctactttggt tacctgcaca ccatatggtg
    40021 ttaacaccaa gcgtctattg gtccgaggtc atagaattgc atatcattat aaaaagtatc
    40081 aacaggctaa aaaagcaatg aaactcgtgg ataaatcaag aatgtgggca gaagtagtgt
    40141 gtgctgcttt cggggtggtt atagctatta ttttagtgtt tatgtattcg cgagtaagtg
    40201 ctaagaaaag caagtgatag ttaaataaga gattgtaata gaaactggtg gactttgccc
    40261 accagttttt tggggtacgg tggggatatc gtacagaaga gctccttcgg ttactttaag
    40321 tataataaaa gaaataaaaa gagtctgagc aatcatgttg tcttagactc tgactgtatt
    40381 atgcaaaaga tgatggactg gcagcttcat ttactcaccg aattcccctt tataacttgg
    40441 gaatgatgct gctaatgggt tgttttgttt aatacctgct ataaacggta atttatccca
    40501 tttatttttg taattatctt caagctcagt tttaaacttc caaaccattt tatgagaaaa
    40561 ataagtgtgt gattgacggc cataggtatc tactaaaacg tgagaaaatt ttccgtcgtt
    40621 ttttagtttg taaaatttat ctagagaagg actccaacca gtataaccag ggaatttatc
    40681 aaattcttga ttaaaatttg tttgttggct tttccaatca taatgccatt gtgtattatt
    40741 gcgtgtttca gaacgaactg taccgtccca ataatgatgc tcataagtta tctctgtagg
    40801 agcttttaca cccttaggaa gaaaaactga gaaatcaggg taaacccatt gttctttagc
    40861 tgaattaaag gttacagtcc attcaatatt tttatcgcta tcgaccaatt ttttagtata
    40921 gtcgacatag ttatcaacat agtaatttcc ctgccagtaa aggtgcactt tacctttctc
    40981 atcaatgtta tcatgggcat gtactgattt atacgaacta aacagcatcg aagctgctag
    41041 tagtgaagtg aagagatatt tattacatcg tttcatatca tgaaaaacct ttcttttaat
    41101 actaatatat tataacaaaa aaactaaaaa
//
LOCUS       DAUGQX010000013        41027 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUGQX010000013 DAUGQX010000000
VERSION     DAUGQX010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41027
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.013"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..204)
                     /locus_tag="VIA51_000611"
     CDS             complement(<1..204)
                     /locus_tag="VIA51_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8682568.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKH"
     gene            complement(273..344)
                     /gene="shp3"
                     /locus_tag="VIA51_000612"
     CDS             complement(273..344)
                     /gene="shp3"
                     /locus_tag="VIA51_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEQ8682569.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            424..1275
                     /gene="rgg3"
                     /locus_tag="VIA51_000613"
     CDS             424..1275
                     /gene="rgg3"
                     /locus_tag="VIA51_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEQ8682570.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1528..5067)
                     /gene="smc"
                     /locus_tag="VIA51_000614"
     CDS             complement(1528..5067)
                     /gene="smc"
                     /locus_tag="VIA51_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEQ8682571.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQCTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEVALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLIRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGANRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5068..5760)
                     /locus_tag="VIA51_000615"
     CDS             complement(5068..5760)
                     /locus_tag="VIA51_000615"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEQ8682572.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6204..7013)
                     /locus_tag="VIA51_000616"
     CDS             complement(6204..7013)
                     /locus_tag="VIA51_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8682573.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(7017..8369)
                     /gene="vicK"
                     /locus_tag="VIA51_000617"
     CDS             complement(7017..8369)
                     /gene="vicK"
                     /locus_tag="VIA51_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEQ8682574.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWIEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8362..9072)
                     /locus_tag="VIA51_000618"
     CDS             complement(8362..9072)
                     /locus_tag="VIA51_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682575.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9234..10268)
                     /locus_tag="VIA51_000619"
     CDS             complement(9234..10268)
                     /locus_tag="VIA51_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8682576.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFTLDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISHHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10324..11571)
                     /locus_tag="VIA51_000620"
     CDS             complement(10324..11571)
                     /locus_tag="VIA51_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ8682577.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLKKADFAVL
                     SSGTTGKAKLFWRRLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(11528..12676)
                     /locus_tag="VIA51_000621"
     CDS             complement(11528..12676)
                     /locus_tag="VIA51_000621"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEQ8682578.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNTVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLSGASDQGIRPRLSSKVLSKVPPILGEG
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13071..13220)
                     /locus_tag="VIA51_000622"
     CDS             complement(13071..13220)
                     /locus_tag="VIA51_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEQ8682579.1"
                     /translation="MQLLDNVYGTLRSFAFMRPAKSSNDTSLADALQAGTDMAFILVR
                     GINYQ"
     gene            complement(13421..14206)
                     /locus_tag="VIA51_000623"
     CDS             complement(13421..14206)
                     /locus_tag="VIA51_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682580.1"
                     /translation="MAKLRCMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFCLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESADS"
     gene            complement(14208..15026)
                     /locus_tag="VIA51_000624"
     CDS             complement(14208..15026)
                     /locus_tag="VIA51_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEQ8682581.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGSSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(15028..16020)
                     /locus_tag="VIA51_000625"
     CDS             complement(15028..16020)
                     /locus_tag="VIA51_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8682582.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQYYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHEFSLDIQYDSSRYQTADIIQKTMADFAVRDVKMTDVDIEDIVRRFYRKEL"
     gene            complement(16161..18104)
                     /gene="thrS"
                     /locus_tag="VIA51_000626"
     CDS             complement(16161..18104)
                     /gene="thrS"
                     /locus_tag="VIA51_000626"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEQ8682583.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKTTHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(18526..19860)
                     /locus_tag="VIA51_000627"
     CDS             complement(18526..19860)
                     /locus_tag="VIA51_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8682584.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGNGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19862..20860)
                     /locus_tag="VIA51_000628"
     CDS             complement(19862..20860)
                     /locus_tag="VIA51_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8682585.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20991..21992)
                     /gene="ccpA"
                     /locus_tag="VIA51_000629"
     CDS             complement(20991..21992)
                     /gene="ccpA"
                     /locus_tag="VIA51_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEQ8682586.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22166..23251
                     /locus_tag="VIA51_000630"
     CDS             22166..23251
                     /locus_tag="VIA51_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8682587.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLVKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23300..23965
                     /locus_tag="VIA51_000631"
     CDS             23300..23965
                     /locus_tag="VIA51_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8682588.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SIGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23976..24353
                     /locus_tag="VIA51_000632"
     CDS             23976..24353
                     /locus_tag="VIA51_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8682589.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24498..25424
                     /locus_tag="VIA51_000633"
     CDS             24498..25424
                     /locus_tag="VIA51_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8682590.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25635..26318
                     /locus_tag="VIA51_000634"
     CDS             25635..26318
                     /locus_tag="VIA51_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEQ8682591.1"
                     /translation="MEWIKLIGIVIIVLGFILKCDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQALTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26318..27244
                     /locus_tag="VIA51_000635"
     CDS             26318..27244
                     /locus_tag="VIA51_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEQ8682592.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27294..27941
                     /gene="pcp"
                     /locus_tag="VIA51_000636"
     CDS             27294..27941
                     /gene="pcp"
                     /locus_tag="VIA51_000636"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEQ8682593.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28057..28776)
                     /locus_tag="VIA51_000637"
     CDS             complement(28057..28776)
                     /locus_tag="VIA51_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEQ8682594.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28782..29249)
                     /gene="smpB"
                     /locus_tag="VIA51_000638"
     CDS             complement(28782..29249)
                     /gene="smpB"
                     /locus_tag="VIA51_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEQ8682595.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29252..31585)
                     /gene="rnr"
                     /locus_tag="VIA51_000639"
     CDS             complement(29252..31585)
                     /gene="rnr"
                     /locus_tag="VIA51_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEQ8682596.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFVLDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPIRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNIDRLTQSALMEINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKIIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYNQPSQEKRDHFAQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVSSVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31679..31915)
                     /gene="secG"
                     /locus_tag="VIA51_000640"
     CDS             complement(31679..31915)
                     /gene="secG"
                     /locus_tag="VIA51_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEQ8682597.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31961..32107)
                     /gene="rpmG"
                     /locus_tag="VIA51_000641"
     CDS             complement(31961..32107)
                     /gene="rpmG"
                     /locus_tag="VIA51_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8682598.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32104..33297)
                     /locus_tag="VIA51_000642"
     CDS             complement(32104..33297)
                     /locus_tag="VIA51_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEQ8682599.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPVRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33419..34921)
                     /locus_tag="VIA51_000643"
     CDS             complement(33419..34921)
                     /locus_tag="VIA51_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEQ8682600.1"
                     /translation="MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISELGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYKLLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHAFRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
                     QAATKKANRRSVGRSHKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35111..35704)
                     /locus_tag="VIA51_000644"
     CDS             complement(35111..35704)
                     /locus_tag="VIA51_000644"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEQ8682601.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR"
     gene            complement(35701..36528)
                     /gene="mutM"
                     /locus_tag="VIA51_000645"
     CDS             complement(35701..36528)
                     /gene="mutM"
                     /locus_tag="VIA51_000645"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEQ8682602.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRL"
     gene            complement(36700..37566)
                     /gene="rgg2"
                     /locus_tag="VIA51_000646"
     CDS             complement(36700..37566)
                     /gene="rgg2"
                     /locus_tag="VIA51_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEQ8682603.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37655..37723
                     /gene="shp2"
                     /locus_tag="VIA51_000647"
     CDS             37655..37723
                     /gene="shp2"
                     /locus_tag="VIA51_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEQ8682604.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38637..38906
                     /gene="stcA"
                     /locus_tag="VIA51_000648"
     CDS             38637..38906
                     /gene="stcA"
                     /locus_tag="VIA51_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEQ8682605.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPILKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39254..39652)
                     /locus_tag="VIA51_000649"
     CDS             complement(39254..39652)
                     /locus_tag="VIA51_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEQ8682606.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRDVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     gene            complement(39745..40740)
                     /locus_tag="VIA51_000650"
     CDS             complement(39745..40740)
                     /locus_tag="VIA51_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682607.1"
                     /translation="MRQIQSIRLIDVLELAFGVGYKEETTSQFSSDQPSQVVLYRGEA
                     NTVRFAYTNQMSLMKDIRIALDGSDKSLTAQIVPGMGHVYEGFQTSARGIFTMSGVPE
                     STVPVANPNVQTKYIRYFKVIDDMHNTMYKGTVFLVQPQAWKYTMKSVDQLPVDDLNH
                     IGVAGIERMTTLIKNAGALLTTGGSGAFPDNIKVSINPKGRQATITYGDGSTDIIPPA
                     VLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQSLNEHEAMVNVEPLSHVVKDNIKVI
                     DEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVGSWLEPATALPSVEMSAEDRLKS"
BASE COUNT        12349 a         8722 c         7204 g        12752 t
ORIGIN      
        1 atgtttgatt ttatcttcta aacacactga gtctaccaaa atttttttat gtttatattc
       61 atccagaact cctatgttgt gatttagata ttcaaataat tcatctgata tagaatgttc
      121 aactggatta ccaagcaatg cagaatacat aaatttcatc ctcctacgtt taattagttt
      181 actactaaca taaagtacaa gcattacaca gagctaacca ttacctataa gtctttagat
      241 actctaaaga cttaagtgta cacctaagta acttacccac caacaataat gataatatcc
      301 attgctaaaa ttaaaatcgg caaaaatttt gaaattttct tcataagcgg acttcctttc
      361 agtttttatt tattgtacaa taaaaaaaaa cggaattgat ttttgttggg aaagtgggaa
      421 aatatgaaat caaaacttgg tgccacactt agaaaagttc gaaaaggaaa gcaaattagt
      481 ctgtgcttcg tggcagatga acacctttca aaatcacaaa tctctcgttt tgagcgcggg
      541 gagtcagaga tatcgtgtat ccgactgatc aatattctag acaaattaca cattactttg
      601 gatgagtttc ttattttaca tgatgaagac tataccaatt ccgaaacatt tgctaacctg
      661 gtacagtata ttcgtaagca atattcatca caaaatatca ataatatagc atgtttactt
      721 tccgacactt ctgattacac tctgaattct tttgagaaaa caatggtaaa gtccatttta
      781 cacacaatgg attcaagcat cattccatca gatgatgaat tacttcaact aacagattat
      841 ctctttaaag ttgaaaaatg gggctactat gaaatccttt tgttgggtaa ctgtgtacga
      901 acaattaact acaactccta cttcctattg acaaaggaga tgttaaataa ttacatttac
      961 tcttcacgga acaaaactaa taaacgaatt gtcactcagc ttgctataaa ttgtttcatt
     1021 cttagtatca ataaggagga attttctaat tgctcctatt taattgatga gataaaaacc
     1081 ttgttagata atgaattaaa cttctatgaa cagacagttt ttctctatgc aacaggttac
     1141 tttgaattta agcgccaatt agaaactgga gttgaaaaga tgaaacaagc catacaagtt
     1201 cttgatattt taaatgaaga caagttaaaa ttacattacg ctgaccattt tgataaacta
     1261 gtcaacaaag attaagtaaa atcattcttt accttttaac gaaacgccaa tcaagggtgt
     1321 ctcaataaaa aatcatctac tctgacaact tttctctttt acctatcgac agctaaaaag
     1381 ccttggaaac tgctatttcc aaggctttct ttgtactcta ttgtatcaat tagcttattc
     1441 cgatttctgt tgctattagt ttaatcatga aatctcctaa cttatggccg aacatccaaa
     1501 aaaacagaag gaactccctt ctgtttttta attggtcatc tcttgagctt cttttaattt
     1561 tacagataca attttagaga cccccgattc ctgcatggta attccataaa tactatctgc
     1621 tgcagccatt gttcctttac gatgggtcac gacaataaat tgactatctt tgtcaaagcg
     1681 attgaggaaa tccccaaagc gcttaacatt tgcttcatca agagccgctt ctacctcatc
     1741 taaaatcaca aacggaatcg ttttaacacg tataatagca aacaataaag ccagtgctga
     1801 caaagctttt tctccgcctg acatcaagtt aagagattga attttcttac caggaggctg
     1861 cacagaaatc tctataccag cagacaagag gtctgtttcc gttaaaacca aatcagcaga
     1921 acccccacca aacatctgag taaaggtttc tttaaaactt ttttgaattg cctcaaaagt
     1981 cactttgaaa cgagccttca cttcgctatc catactatta atagtctcta gcaaaagatt
     2041 tttagctttt gtcagatctg tcttttgact tgttaaaaaa gtcaaacgct catgcacttc
     2101 ctcatactga ttaatagcat cactattaat tggtcctagt gcacgaatag tcttttgtaa
     2161 atggtgtaat ttttctttgg cactttctaa gtgatcaata ctatttgtta cctcctttgc
     2221 gtctgctagt gtcatttgaa aatcttctga taaactttta gcataggctc gtaagcgatt
     2281 agccacttgc tctaaatgtg tctctaactt ggtttgacga cgaataaatg tgtcattttt
     2341 ttcgctttct ttggttattt tttctgctgt ttcttctaag cgggcctcat agtcctctat
     2401 ttcaaatctt aattggacta aacgtttttg agcaccagac ttatgctctg tggcatcttg
     2461 taactgtttt tgccactggg gtagtctttg aatgctgtct tgacttacgt tattgtttag
     2521 tatgctttca agtttgagaa tattttgctg gcattgcttc agctgagttc ttagacgaga
     2581 ttgattagct tgctcaaatt tcttttcatt aagtaaatct ctttcttgca aacgagcttg
     2641 agataaagct tggtgaatgt tttgtgtttt ttgcctaatc aaatctttgt tttctttgat
     2701 atcatcaata tcacaagtta aggcattttt tttcttagca atagctgtta atgcttcttc
     2761 aatacgagct tgttctgcca ataaagattc atcagaatga gtcgtctgac tttggtcaag
     2821 ggcagctaac aaagcctttg aatcttcttg tttttcttgc aattgctgat aagccatttg
     2881 agctctttgt tcagctaagc gtgcctggtc accggctaat ttcaattgtg tcagttcttc
     2941 tttttttgct atcaaatcgc tttgcaaggc agctacttct ttttcagtta tttttaattg
     3001 ctcaactaat cgcgttaatt cctcactgat ttgttctaac tctggtttga taaaagttgt
     3061 attgctttgt ctattagctc ctcctgaaaa agaaccacct ggtcgtaatt ctgttccatc
     3121 aagagtaaca attcttacct tatatcctaa taagcgcgct gcaatattag cttgatcaat
     3181 agtttcaaag atagcagtac tagataaaag attttggata atagctgaaa gactatcatc
     3241 atagcgaatc aatgattctg cagttcccag ataaccttca caagtcgcca attgacgatg
     3301 atagtgttct gataatgatc tagcctttat agtagttaaa ggtaaaaaag ttgctcgtcc
     3361 ttggcgattt tttttcaaat aagcaattgc tctttttgct gcagcttcgt ctgttacaat
     3421 aatatgctga ctattagcac ctaatgcaac ttcaagagct gtttggtaat cagaatcaaa
     3481 agaaaggtgt tcactgactg cacctatgat ccctccaagc tttttttgtg attgaaggac
     3541 agctcgtact cccgcataga attgactatg acttttttga atagattcta agctagcctt
     3601 acgagcttct tttccttttt tttgatccaa caagtcaaat agtctttctt gattcagttg
     3661 gtaatctctt tctaattcct gaacgcgttt atcaccttct tgataatttt ggagcaacat
     3721 ttcgacttgc tctttttgag ctttataatg agcttgagct ttttgagact cgtcattaag
     3781 ttgatcaagc ttagtaacaa gtagctgata ttcttgagcc ttatgttgac gagcctgttt
     3841 ttctttgtct aaatgggctt ttaaagctgt cagctgattt gataaggccg cctctttttg
     3901 catcaataat acaaactctt ctcttagagt ttccattaat tggtcgggat cacttgaaaa
     3961 acgctctaat gcattgctca attcgtttaa ctgttgtttg acatcacaaa gttgttgatc
     4021 aatatgcaat aattgttctg tacactgctt ttcttctgct tgaaaaccat ccaattgttc
     4081 ttgtaactgt tcgagatgtt ttttggcttc tgcctttttc tctgcttctt ggccactttc
     4141 tagcttaacc aattcaattt gcttttccaa gtcagctatt agcttggtta attctaataa
     4201 tgttgtttgg gtttgatctg actcttgact aagaacctgc tttttttgct tgaatttttg
     4261 gtaatcttct tccatagatt gacgcttagc gtaataagat gctaagtctt gttgtaaagc
     4321 agctaaagct tcagtatctt tagtctgtct ttcttgagct atatcaatat ctttgactag
     4381 aatatctagt tgtagttgct tacgattggc atcaagttct aaaaattgtt tagctacttt
     4441 agcttgcttt tcaagtggtg ccaactgcgt gtctagctca taaataatat cctctagacg
     4501 gtctaaatta tcttgagttt gatttaattt aatctgagtt tcttttttac gtgttttata
     4561 ttttaaaaca ccagctgctt cttcaaaaat ggcgcgcctt tcttcaggtt tactattgaa
     4621 aatttcctct acgcgacctt gagaaataat ggagaaagaa tcacgaccaa gccctgtatc
     4681 cataaacaaa tcatgaatat cacggagcct taccttgcga ccatcaatca gatagtcact
     4741 atctccattt cggtaaatat gcctttcgac acggatttct ttcttggcag tttttataaa
     4801 atgatcggaa ttatcaagaa caaccgctac cttagcatag tttagaggat tacggttttg
     4861 tgtcccagca aaaatgacat ctggcatctt gcccccacgc agatttttag cacttgattc
     4921 tcctaaagcc caacgtaaac tttctgtaat attactttta cctgaaccat ttggtcctac
     4981 gactgcagtt actcccttat caaattcaat tttagtcttg tccgcaaagg acttgaaccc
     5041 ttccaactca atttctttta aaaacatcta aacctcacta agttgggcaa gggcattttt
     5101 agcagcatct tgctccgcta attttttaga cttacctaaa cctttactaa ggacagcacc
     5161 attaacaact atcgatacct caaattgttt agcatgggca ggtcctttct cactaatgac
     5221 ttgataatca atagccacat caccttttgt ttgcaaaaac tcttgaagac aagttttata
     5281 gtctttaacc ctttcaaaat tccctttttc cacctgagga atcatgactt gtttcaagaa
     5341 gcgacgtact gcatcaatcc ccttatctaa taaaagagca cctaaaaagg cttcaaataa
     5401 gtctcctaaa atagtatcac gacggcgacc acctgacttt tcctcacctt ttcctagttt
     5461 gatataagcg tcaaaagaac aaaatcgtga aaaacctgcc aagctttcct cacgtacaat
     5521 catggaacgt aacttagaca tatctccttc tgtcttttta ggatactttg caaataaata
     5581 ctctgaaata atcaattgta gaacagcgtc tcctaaaaat tccaagcgtt cattatgtga
     5641 aacgtttagg agacgatgct cgttagcgta agaggtgtgg gtaaaagctg tttctagtaa
     5701 agtcaaatca ttaaattgaa tatcaaaaga tgttgagagt aactcttcaa gctgtttcat
     5761 aaaaaatccc tttcatattt gtcagtagac cttatttagt ataccaaaaa tccacctaga
     5821 aaaccgactc taagtggatt tttcgtgatt tattaaacat cttaaatacc cgtcaaagga
     5881 aactttctca tacaatcaaa agactctaca ctatctgagg ggaatttccc actacagtcc
     5941 cactacagat agtatagagc tatttttgtt tttagtctga acaactaaaa aactacctca
     6001 tctttataat cctcaacacc tttgataaat agatcagaca agccaaaact acaggctaat
     6061 ttaagtctat tgatgctcta aaggatgacc aatgagagtt cgttgaactc agaagacaat
     6121 acgctttaag acatcaaaaa atagccctga ctggtatatc accaatcagc gctactttgc
     6181 atattctctt ttagtttctt atctcaaata tcagttaatg gacaagcagt atctggagag
     6241 gtatcatgga ccgtaaagtc tgtacctact gctaaatctg ccatagccag ttgattgacc
     6301 atcgtcatat gcgctaactc tttgatgtta ttttctttac tcagatgacc taggtatatt
     6361 tttttggtat tgtaccccag gcttctaatc atggctcccg ctccatcttc atttgataaa
     6421 tgtcctaaat cagataaaat acgctgcttt aagctccaag gataagagcc tgatctcaaa
     6481 atttcaatat catgattgga ttcaatcaag tagccatctg cattttcaat aatacctgtc
     6541 atcctatcac tgacatatcc tgtatctgtc aacatcacaa aagacttatt atctttcata
     6601 atccgataaa attgaggatc aatagcgtca tggctgactc caaaactttc gatatcaaca
     6661 tctccaaagg tcaaaacttt atccctttgg aaaatatgtt tttgtgaggc atcaagctta
     6721 cctagcatat tgcactcatc catcagctgc catgtttttt cattagcata gatatccaaa
     6781 tggtatttgc gggccataac gcctacaccc ttaatatggt cagagtgctc atgggtaatc
     6841 aaaatagcat ccaaatcctc aggtttgcgg tcaatttcag caagaagact ggtaattttc
     6901 ttaccagtaa gccctgcatc aatcaataag cgttttttag gtgtttctaa ataaaaacaa
     6961 tttcctgtgg acccagatgc taaaatactg tatttaaaac cactctcatt cattaattag
     7021 tctacatctt cctcccattc ttcatagatg gctgcatctt tttcataagg caagacaata
     7081 gtaaaggtcg atcctttacc atagtcactc ttagcccaga taaagccatg gtgctgcttg
     7141 atgatttctt tagcaatggc aaggcctaga ccggtccctc cttgggcacg acttcttgcc
     7201 ttgtctacac gatagaaccg atcaaaaata agaggcaaat ctgttttagg gatacctagt
     7261 ccttggtctg aaatggaaat aattaattgg gtatctgttg ttttcatacg gactgtaatt
     7321 tttccaccat ctggagaata cttaatggca ttgttcaaaa tattctcgat aacctgtgtc
     7381 attttatcat tatcaatttc aatccagaca gaggtaatag ggtaatctct tacaatttca
     7441 tagacttttc ctgtacctgt atgctgattt ttaaccaaat caaatctgtt taaaatagaa
     7501 gttataaaag cagtaaaatt agtcatctct actgctaatt gggttacttg attatcaatc
     7561 cgagacaggt ttaaaagatc tgaaatcata cgcatcatcc gattagtttc atcaagagaa
     7621 acttttatga aacttggagc aatatcttct ttaagtgcac cttcatcaag agcctccaag
     7681 taggatttaa ccgaagttaa aggggtcctt aattcatgac ttacattaga gacaaaaaga
     7741 cggcgttcac gttcttcttt ttcctgttct gtggtgtcat ggagcaccac aaccaagccc
     7801 gaaataaaac cactctctct cctattcaac gcaaagcgca agcgtaatga gacaaactca
     7861 cccatatcat ttcggctatt aacagttacc actggtgttt tggataccaa atcacggtag
     7921 gtatatgaag tatcaccttc taacaaatct gtaatgtttt tctttagtgc ctcttcttta
     7981 cttaaattta attgcttgcg agctgtctcg ttaatcatga tgattttacc agaccggtct
     8041 gtagcaagta caccatctga catataagcc aaaatacttg ccaagcgatt tttttcttgg
     8101 gcaagatttt catgcgtcaa gcgaaaaaca tctgacaggt catttaactg gtctgaaagc
     8161 tccattaact caatgtctgc tttttcgtcg attatatcag tatagcgacc attaatcaag
     8221 tctcggattt tatggctcat catccgaata atacgtgcat ttcggtaatc acgcaccgca
     8281 agatggataa agtaaaaagc aacaaaaaca agtaagataa ggatcgctaa ttcaaatgtg
     8341 gataagtttc caatgatatc tctagtcata agatttcatg tagtacccaa caccacgtct
     8401 tgttaaaata tactcaggac gacttggtgt gtcttcaatt ttttcacgga ggcgacgaac
     8461 agtcacatca accgtgcgca catcgccaaa ataatcatat ccccaaacaa tttccaataa
     8521 gtgttctcgt gtcatcacct gccccatatg gttagctaga tgatgcaata gttcaaattc
     8581 acgatgggtc aactctacct cttgaccatg ttttttagca acaaacgcat ctggtaaaat
     8641 ctgtaaatta ccaatggtca gttcctgtgt acctgaagaa gcattttctt ctgcaacagc
     8701 cgtttcaata gtttcggtac gacgcagatg agccttgaca cgcgccagca attcccgatt
     8761 agaaaagggc ttggtcacgt aatcatcagc cccaatttca agtccaataa ccttgtcaaa
     8821 ctcactatct ttagccgaca acataataat cgggacatga ctggttttac gaatttcctt
     8881 ggctacttca agaccgtcca actcagggag catcaaatca agaataatta aatctggctt
     8941 ttcttcttca aaaattgtta ccgcttcgcg tccatcaaaa gctgtaacaa tgtcataacc
     9001 ttcttttgtc aaattaaact taataatgtc agaaatcggt ttttcatcat ccacaataag
     9061 tatttttttc atgtctatac ctcagaaagt tcttgtaatt gatattacaa tttgtgattt
     9121 ttgtggttaa taaaaaatca caaaactata tttttctaaa ttatttctac ctgattatac
     9181 caaaaattca gcctaattga caatgacgac taccgttaca aatagagtac tttctaaaac
     9241 caacccttta taggatgaat ttgacgtttg aattgcttag ctgatttttt gactctggca
     9301 aaactactct tgttgtggta agcaaaaagt cctttggcat taaaataaga gaacataaag
     9361 tcatcttttt gagctctaaa ccactggcga aatactcttt ttggcgatcg aaatccttta
     9421 agggtgtctc ttctaaactg aggatcgtga tggctaatcg gatcaacatc taaatcccaa
     9481 tgtctaggac catctgtgcc atagttaaaa gatgcaccat tgacaattcc tttttcggtc
     9541 actacttctg catcaacttc attaagaaaa aagcctgtgc tatctagagt aaattcggta
     9601 tgaaaccaaa gaagtacttt tatattatag gaaacttctt gacttggaaa aatgacttta
     9661 ttatcttcaa atcttagttt attatgtaac ctggcagaat ccatcaaggt ataatctggt
     9721 gcttgccgcc acaaacaagg ccctttttta gacctcaaaa aaagggccag agcttgggcg
     9781 tctgtcatct caatcatttt ataatggttt ctgatagatt gagcttgttg actagagatg
     9841 acataacgaa attgatgcaa acgcttttca agctcacctg cttggcttag tgttttgcca
     9901 ggaaaagctt gatcaactaa gctagccaac tctttccaaa acatatgatc tggcaataga
     9961 gatggatgga atcgggtgag tagcgtttga gtttcatgca actgaccact tagctcaaat
    10021 ggcatctcta ccaaatcaag aagaaacgtt agtaactgct tagctgattg gttttctttt
    10081 tcaataggcc atattaccca gaaagttgga gaaccaagtc gattatcaat gataggctct
    10141 ttagctatag cacgaaatgc ttggtttgat aaacctgcgt tttgatagca tttcaaggcc
    10201 tgatagcgat ctaagatagc ttgtttcatg gccttctcct catctttttt gaccatatta
    10261 taacacatct aaagctgaat cgtcacttgt atctcactat aagcaaaacg aaacctgaag
    10321 tggttaacta agccactgtt tgggtatttt atttaaaaga acttctcgat taattttacc
    10381 attatctttt aaaggcaaac aatcaatcac aagatagtac ttgggaagtt gtccagagtt
    10441 taaataaaga gctaaaaagt ctttaatagg tgctaggcaa tccttcttag tcaaaactaa
    10501 tactaatatt agggtttcgt tttctccttt tcctatcttt aaagcgtgcg cttctttgac
    10561 gtttggcgct tggtgagcga gttcaactag gctaggcagg tggcatttca ctcctcgttg
    10621 attaacccag tcatcttgtc gcccttctaa aattaaaccc gctgggctca tttttcctaa
    10681 gtctgaaaca ctgtatggtt gtgacattcc ttctacacta taaggagtct ctacaaaaat
    10741 ttccttatct ttgaaactga tagacacatc aggaaagggc tgtcctacca aaccattaat
    10801 tttgacagca gctctgccat tacaccacgt tataaaagat aattcactag ccccgtagaa
    10861 aatgacaatt tcaagctgag gaaatttttt gtaataatgt cttagtaatt cttgtgatat
    10921 catttgcgaa gaggtcaata agtgagtcgc agtcatgttg ttcttagtca aataaggtag
    10981 caagcgattt aggtaggtcg gtaaaaggta aaggtgactc accttttttg cttgccataa
    11041 gcttaaccac gttttcaaag acagcttttg gcttaaaacc agacatcccc cggcccatag
    11101 ttgagctaat gctaagttaa gattgccagt aaaactaaaa ctaccatgta agaatagaca
    11161 actattacca gtcataccaa acaccttatt ttgataatca aaaagtctcg tccaagttga
    11221 tagacgacgc caaaataatt ttgctttgcc agttgttccc gaactcaaaa cagcaaaatc
    11281 agctttttta agaagctcac catcgacgtg ttttatttgc tgctgaaatg tacctgagat
    11341 attagggtgt aaaatgatag gacaactgcc ttcttttaat cctcgtaaaa aagagagtaa
    11401 ctgattaaga tagcgactat gactgatgat atatggtaca ctgtctttta ttgtctgatc
    11461 ctttattaaa accgcttgcc atagctcttg ataagtcaag cttatctgat cggctacgat
    11521 agctttttta tttgggcatt gctttgccca atattctagc tttgtcagca tgactaaact
    11581 ccttatgata ttttagtaaa acagcaaacc cttggccacc agctgctgct atagcagcta
    11641 ttccatagcg tccattttta atctctaaag ccctcattaa gtgcaatatt ataatggctg
    11701 ctgaggcacc atagggatga ccataagcta atgcaccacc aaatatatta tagcggtcca
    11761 ataaatctgg ataatgggtt tcaaatagac catcaataac ggcaaaggct tcgttccatt
    11821 caatcgctgt catatctgcc atccctagac catgtttttc caaaaggact tgactagcct
    11881 taatcaccat taaagggcta cgctgtgggt ctcctgctac ttctaccaca tcaatcagtt
    11941 taaaagctga aggctgacta cttagctgta aaaaggcagc agcatcatgg gttaggcagg
    12001 cattggctgc actaatcacg tgaccttctc ctaagatagg gggtaccttt gacaacacct
    12061 tacttgacaa gcgcggtcga ataccttgat cactggctcc tgacaggtct agaataagat
    12121 cagctaacag ggcttgctcc tggcaataac tagccttttg atgacttctc aatgtccagt
    12181 gattcaaata ctcctttgta aagccatgct ctcttgccac tcgttctgcc ccttcaatca
    12241 tcgcaaaagg gctgatacta tctggagaaa actgagctac cttgtaggct ccttggcgcc
    12301 aatcagctga agcatatacc gattcaggtt gtaaggagct gctttcaatc cctcccacta
    12361 aaaggttgct tgccatacct gccttgattt tagcataacc cacggaaaga gctgcaccag
    12421 ctgatgcaca ctgcatatca accgtcaaag cagagacaga ttctcctaaa tgagaataca
    12481 gggtcatcaa gcgcccaata ttaccacccg ttccgacggt attgccacaa atcacttggt
    12541 caatgggaac tggatactta ttttgtaaag cgttgatgag ctttgctcca aggatttctg
    12601 gttgttcttt agcaaattgt ttccctacta aaccgatagg ggttctaagg cctgcagcaa
    12661 tataaacatc cgtcattata ttgacctcct ttattttcga tgtccttaaa tggttattgt
    12721 ataattattt ctgatggttt tcttttttga actaataact gctaaaaata cacctaaatt
    12781 aatttagaga atctctttag tctcgctagt gtgctatcaa taaaatctat aaaattctct
    12841 aacgtcattg aaatgtcaag tcccacaact attgtcgtag aagtcactta ctttgttgct
    12901 ttaacattca aactgtaacc tttgtttttg atacagggtg actttattat actggaaaac
    12961 cattcctaag aaaagaaaat cttatataga ataaagaatt agacaccata aaaaagctaa
    13021 gctgtgacac ttaacttttt tatggtattg acaaaccttg tctttactat ttattgatag
    13081 ttaatgcctc taactaaaat aaaagccatg tctgtaccag cctgcaaggc atctgctaag
    13141 ctggtatcgt tactagattt ggcaggtctc ataaaggcaa aagatctcaa agttccataa
    13201 acgttatcta gcaattgcat gcaaccactt gaaacatatc tgcttatgtt attttaccgc
    13261 ccttaattta gaccaatctg ctgatgatgg ttccaaccaa tgcctacgct tggtaaacca
    13321 tcacaaaaaa aggcagccgt ttttacaaca gctgccttcc ttcattatct aggttttcat
    13381 attctgacct aaacgatttt caatttgttt aagagtctct ctaggaatct gcactttcat
    13441 aagcatccag gccccatttc caaagcttaa gcgacaaggc caaaaccagt aacgacacca
    13501 ctaccaagcc tccaatatta aagagcaggt gttgacctgt taaaaaataa gaagcagggt
    13561 aataagctgt aaaagcaaag ggaatgataa aactgattaa ccaccgcaaa aaggaatggt
    13621 aaatggacat agggtactta gaaaagtcat tgaacatgta aaaaatatag ataactgccc
    13681 cagactgctt ggtccaaaaa gaaatgctgg cggtcgcaat ttttaaagag gtgtaaatca
    13741 aggtcgcaaa aggaataacc aaaataaaca aaagcacctt aggaagagtc catacgatac
    13801 taccagccgt ggtcactaat aagataaccc caaccaataa ttcacccagg gcatccactt
    13861 gaaaggtctc aactaaaaca tgaaacaaag gactaattgg tctggtgagg tacttgtcaa
    13921 attctccttt gcggacaagc cgttgcccta aagcccaaag attgtcaaaa aagaggtgat
    13981 caattccctt tggaatcaaa caaaagccat aaataaaggc aatttgttca aacgtccagc
    14041 cttctaaaga agggatatgt tggaaaagta ccgataaaaa gagcagatta agtccctgag
    14101 tgagaaaaac acctagcact cccaccacaa aatcaacctt gtattccata atttgtttga
    14161 ggtattgttt gataaaaata gcgtgcatac atctcaattt tgccatctca ccctccttga
    14221 atcgttaaat ggtactgaac ctttttccag atgacttgcg ataagactac catcaccagt
    14281 aaccaaaaga tttgcaaact tagggccacc attatctgac taaggctgta tttcccaatg
    14341 acaatcataa ctggcgtgta aaccaaagag gaaaacggta gaaaactaag cactatagaa
    14401 accattttag gaaaaaaagc caatggaatc aaactgcctg acataaaggc aaccaaggca
    14461 tttttcaata aattagaccc ccaaaggttt ttaaagacaa atgctgaaga gccaaaacaa
    14521 atgttgaaat aaaaattgat taaaaaagct aataaaaggc taactaaata cagacaactg
    14581 ctggctagga cttgcaagat agacagcccc gccatgactt taataccaga taagaccatt
    14641 aaaaaaggaa agccgacact cattagcaca atccagcgaa aaccaatttc cataaagagg
    14701 taagaggctg caaaatgaac tggtcgaagc aggcgcatga tgatagaacc atctttcact
    14761 tcttcgccaa tcataaagga gctgtctgat ttggtcagta aagtggtcac aaaactcatg
    14821 ataatgtaaa aggtcatgtc agacagagta aaaccattga ttaaggattg cttagacgaa
    14881 tcaaaaacag ccttccagag gtaataagcc acaaaagccc ccatgacatc tccaatacga
    14941 tacaaaaaga aattaacgcg ataggttatt aattcctgaa ttcctgcact gagaaagggt
    15001 ctataacgtt tccaaaatga ccacatctta aagctccttt cggtagaaac gacgaacaat
    15061 atcctcaata tctacatcag tcatcttcac atccctgacc gcaaaatcag ccatggtttt
    15121 ttgaataatg tccgcagttt gatagcgcga actgtcatat tgaatgtcta aactaaactc
    15181 atgccgttcc actgtgatgt caggtaagcc cataaactgt gagaccacct gctcctgccc
    15241 tggcttcaac tcaaaagaca gactcttcat ttttccaaag ctttgcttta attgggtcac
    15301 cgttccatca aagatttctt gccctttatc aatcatgata atccgatcac agagctgttc
    15361 aatatcactc aaatcatggg tcgtcagtaa aatagttgtc tcttcttctt gattaatttg
    15421 agtaatggca cgccgaatgt tgtccttcac agaaacatca agtccaatcg ttggttcatc
    15481 taaaaacaat actttaggat tatgcaacaa ggaggcagca atatcagctc gcatccgctg
    15541 accgagtgat aaggtccgga caggatcctt aataaactca ttcaggtcca aaacctcatt
    15601 taaaaaatcc atgcgcttgc gaaaggcttt ttcaggtaca tcgtaaattt cttttaaaac
    15661 gacataggtc tcttgcaagg ccaaatccca ccatagttgt gttcgttgac caaaaacagc
    15721 tccaatgtct ctcacataat attgacgatt atcttgtgga atctttccgt taatgcgaca
    15781 gtaacctgat gtaggcttta aaatacctgt taacatctta atcgttgttg attttcctgc
    15841 accattggcg ccaataaaac ctaaaatttg ccctttgggt acctcaaaag ataagtcctt
    15901 aaccgcctca aagatttctc tttggggatg aacaaacgac ttcaaggctc cctttaatcc
    15961 tggctcttta atggttttgg aaaaattttt ttgaaggtgg gacacttcta tcatgaccat
    16021 ttaccattcc tcgtttctgt tatcgtctta tcaccgttac taaacaattt attataacac
    16081 cataaaaaag acggtgcaac cgtttgctta attttttaag aaagaaaaag aagcccataa
    16141 ggacctcttt ttgccattga ttaagcttgt gcatctggac gtgacttgcg agcaatgtct
    16201 gccaagatgt tttccacaaa ttcttccaca gattcggtgt gagtcgtctt gctaccatag
    16261 cggcgaacat tgactgattt gtcttccatt tctttgtccc caacaattaa ttggtaagga
    16321 attttgctgg tttgagacgc acgaatcttg tactgcattt tttcattgcg gtcatcgaca
    16381 tctgcacgaa caccacggtc acgaagggtt tttgctactt cccaagcata gtcaatgtgg
    16441 gcttcatttg aaattggaat cacggttact tggtgaggtg ccaaccaagt tgggaaagca
    16501 cccttgtaag tttcaataag gatagcagtg aaacgttcca tagttgagat aacaccacgg
    16561 tgaatcatga ctgggcggtg ttcttcgcca tcagcaccaa tgtatttgag atcaaagcgt
    16621 tctggcaaca agaagtccaa ctgaatggtt gatagggttt cttcgttacc aagagctgtt
    16681 ttcacctgaa tatcaagctt aggcccataa aaagctgctt caccttctgc ttcaaagtaa
    16741 tctacaccca tctcatcaag tgcagcttta agcatacttt gagcattttc ccacatctca
    16801 tcattgtcat aatatttatg agtatcgtta gggtctcggt atgacaaacg aaaacgataa
    16861 tcagtcaagt tgaagtcagc ataaacatca atgattaatt gaagggcacg ttgaaattct
    16921 tcctggattt gctctggtgt tacgaaaatg tgaccatcat tcaaggtcat ttcacgtacc
    16981 cgttgaagtc ctgatagggc acctgatttt tcgtaacggt gcatcatgcc aagctcggca
    17041 atacgaatag gcaattcacg ataagaacgc acatgatttt tatacacttg aatgtggtgt
    17101 gggcagttca ttggacgaag aacaaactcc tcaccatctc ccatatccat tacagggaac
    17161 atatcttctt gataatgatc ccaatgacct gatgtcttgt acaattctac agaagcaagt
    17221 ggtggtgtgt aaacgtgttg gtagcctgat gctaattctt tatctgtgat gtagcgctca
    17281 agtgtacgac gaatagtcgc tccatctggt aaccaaaatg gcaagccttg gccaacttct
    17341 tggctaatca tgaacaagtc aagctcttta ccaagcttac ggtgatcacg ttctttagct
    17401 tcttctagac gagtcaagta agctttgagg tcttttttat caaaccaagc tgttccatag
    17461 atacgttgca tcatgttatt gtcgctgtta ccacgccagt aagcacccgc cacattgagc
    17521 aagtggaaga cttggatacg gcctgttgat ggcacatgag ggccacggca aagatccaca
    17581 aattcacctt gacggtaaac cgtcaagcca gcaccagcat gctcattaat caattctacc
    17641 ttgtaaggat catctttgaa caattccaaa gcttcttctt tggtcacttc ttcacggata
    17701 catgggtaat tttctgtcac gattttttgc atttcagctt cgatacgtgg caaatcttcg
    17761 tttgaaattt ggccttcagc attatctgta tcatagtaaa agccttctgc aatggcaggg
    17821 cccacaccca aatgaagatt tgggaacaag cgttttgcag cttgggcaaa taaatgggct
    17881 gcagagtggc gaagcacctc ataagcatct ttgtggtcag gtgtcacgat ttcaatactg
    17941 ccatcttctt caatggcacg agtggtgtca atgagttgat cattgaactt accagctaaa
    18001 gcttttttag ccaatgattt gctgatggac tcagcaatgt caaacgttgt tacgccagat
    18061 tcaaattcac gcacggcgcc atctggaaaa gtaatcttaa tcatttgctt tctcctttaa
    18121 gtcagttaag atttccacta aaacatggat agtaagacaa attagggaca agaggttagt
    18181 gaatagctca ataccaccac gtagaagaac aataccttat tcacgaatct accctcccta
    18241 gtccttaaaa acaaggctaa tcccctccaa aacaaaaaaa ctgaccgcat cccaaaggac
    18301 gcaatcagcg tggttccacc ttaatttatg caggacaaaa aacatgcctt gcacctctag
    18361 tggcgataag ggggccaccc ttttatgttt gcataaaaac caggaaggag tatcagatta
    18421 gctatccttg tgctctttcc accaaccagc actcgcttaa aagattctgt ccaatctaac
    18481 ttgtcttcaa gataattata gcaagttttc aaaaatttac aagtcttaat ccagaaaatc
    18541 tttgatagca tggaccagct tgataggagc cttgactact tttactgagg tgatagctgt
    18601 gaccttagca gcacgtttag gcaagtgaat agcaccttgc actaatttta gagaactact
    18661 tttaccagaa tgattaagat aaagactcag cttttgagct tctttgctat ttctagcaat
    18721 taacgtatct aaatagaacg tgtaaataga ttttccaaag tgctgtgctg agatttcata
    18781 acgttttttt gctaataacc gtttatccat aactggtgtt tttagtatgg catcaataat
    18841 agcatcagtt aaatctgttt cagcgtaata aagagtgcca aacattttat cagtcaccac
    18901 atcatctaaa taaggattgc catgagcaat aataggagtg ccactagcca aactttcaat
    18961 ataggtcaag ccctgagtct cactagttga tgctgagata aagaaatcac aagccttata
    19021 gtacagagca accttatcat gaggcaccat gcctgtaaag gtcacgtgtt tgtcaacctc
    19081 taactgcatc gccaagtgtt tcaaatcttg caaatagggg ccatttccta caataataag
    19141 ctttatcttg gcattttcag ccaaaatagc tggcatctga ttgatgatag cttgaatatt
    19201 tttttcataa gaaatccgtg acaaactcaa taacatggtt tcatcaccag caatgcccaa
    19261 ttctgctttt aagttggtta cttcttctgc tgtgatgtca tcacgaatat atttttccaa
    19321 aggaatgcct gttgggataa cccgcttagg gatagtaact tcgtaacctt ctagaagatt
    19381 gaggacaatc ctacttgggc agataacccc atccaaatcc ttcaaatagc ccctaagaag
    19441 aggtttgacc atacttggtc gaatgatttt tccgttggca atataactca cgtagtcctc
    19501 atattgggta tggtaagtat ggacaacagg aattcgcaaa gctttgccta tcattttccc
    19561 taataagcct aagctaaact cagtttgcgt atgaataata tcaagattat agtgttttgc
    19621 aattttgtat gacgaaatga ggccacgata aaccacacgt ctatccgtaa atgacacaaa
    19681 aggaacactt ggcagtcgaa taatggtcgg gtcttcaaag cgtttgacat ctctatcagt
    19741 agtggtgaaa atataaactt cgtgaccttc tttttctagc tcttctttta acgtacgaat
    19801 actagtagcg actcctgaaa cttgtggaaa ataggtatct gtgaatagac ctatacgcat
    19861 cttataactc cattactttt ttatagacat ctactaaggc atggccaacc gtttctaggc
    19921 gacgactctg ggcaaccttg taaccagctt caactttgtt gctggcacca gaaaagactt
    19981 ttttcagagc ttctataaaa cctggtatat cggttgctaa ttccgcacta ctttgatcaa
    20041 cccatccgta gtaaactggt atatcacgta aaacaaggtg ctggcgactg gccaaggctt
    20101 ctaagacaac aatgccttct gtttcttcac gacttggaaa gaaaaaggca tctgcaccag
    20161 tcatggcacc ttcataaaca tcccctttaa tgtatcctgg gaaaataaga tttttcgggt
    20221 ggttaccatt gaccatttgg cgaacttgag caggaatgac ccatttgttg gtctcgccaa
    20281 accagataaa acgaacatct ggcatagctt gggcaacttt gacaaagtca tcaattcctt
    20341 tcctcagaaa aaataatcct gctcccataa ccactttttc accctcttta atgtcaaagt
    20401 agcgacgaaa agctgcttcc tttttaggat ctgctccgta ctgctccaaa tcaatcccat
    20461 ttgacactgc aaaaataggt gacttcactc cataactctc aatcaaagac ttagaatata
    20521 gggtaggggt aatgatagca tctgccttat tgtaaaagtg acaaaggtat tttttaaacc
    20581 aaggagataa tagatttgaa aaaataaaag aatttctaaa atcttcttct gtagaatgcc
    20641 catgcatgat aaccttctta ccagcttttt gtgcttttat catcagcagc caacttttta
    20701 aaccataggt attgagatga accaaatcat aagtttctct tggattagtc gtaaaatgtt
    20761 gaccaacaag tgacaaggct ttagcctgat gcttaatcgc tcgaccaatt cctgattttc
    20821 ttagataatt ttctgcttct aaatacaata agactttcat aagttctatt atagctcatt
    20881 ttatagtatt tttcactaag acatgcaaaa atcagcccta aggctgattt tagtattgaa
    20941 gaaacagtct attgtgatac tttttgttag atggtgctca taattcacag ttacttagtt
    21001 gtcccacgtt ttttaatacc atgattcaaa agaatttctt tttcttccaa ctcttctttg
    21061 ttcatgattt tagtcaacat ccgcatgcta acagcaccta agtcataaac aggttgactg
    21121 atagaactca aattgggacg agtgtattga accactggtg aatcgttgct ggtgatgatt
    21181 tcaaagtcct ctggtacgcg tttacctgct tcaaacaagc cgtttaaaag gcccgctgcc
    21241 aattcatctt cagccacata agccgctgtt gctcctgagt taatgacgcg ctgcgccaat
    21301 tcaaatcctt ctttataaga atagttcgct tcaaaaacaa ggccttcttt gaagtcaagc
    21361 ttattgtgct tcaacccttc tttgtaacct gctaagcgca ctttaccatt gatatcatca
    21421 atgagtggtc ctgacacaaa agcgatacac ttatgatttt cagctaaaat atcaacaacg
    21481 tttgacaccg cagctctata gtcaatgttg acgcttggta attgatgatc aagatctaca
    21541 gttcctgcca aaacaactgg agtacgagag cgtgaaaact cggcccggat tttttctgtc
    21601 aagtgatgcc ccataaaaat aataccatcc acttgcttgg caaaaagggt attgacaaca
    21661 ttaacctcct tgtcatcatc ttcatcactg gaggcaagca caatattata tttgtacata
    21721 gcggcgatat cgtcaatacc cttagctaag atagaaaaat aactatttgc aatatttgga
    21781 atcacaacgc caacggttgt tgtctttttg ctggcgagac cacgcgcgac agcattggga
    21841 cgatagtcaa ggcgatcaat aacttctaaa actttcttac gtgtattttc cttaacattt
    21901 ttattgccat taacaacacg actaacggtt gccattgaaa caccagcttc acgggcaaca
    21961 tcataaattg taatggtatc atctgtattc attttttatc ttcctttcta tttgaaaatg
    22021 acgctttcaa aaagtatttt agcatgattt gtaaccactt tcaagtgtta taggttaatt
    22081 tttgaaaaag ttttcaaaaa ttaactcgaa gcttgatttt ttaagctttt tttgaaaaaa
    22141 tagtaagtag aaagaaggtt agcctatgac aaaattagac caaatacgtt tgtatcttga
    22201 ccaaaaggga gctgaattgg cgattttctc agatcctgtt acgattaact atttaactgg
    22261 attcttctgt gacccacatg aaagacaact gttcttgttt gtctaccatg atttagctcc
    22321 tgtgcttttt gtacctgccc ttgaggtggc cagagctagc caggccatat catttcctgt
    22381 gtttggttat gttgactctg aaaatccttg ggaaaagatc aaggccgttt taccaaatac
    22441 agcagccaaa accatttatg ctgaatttga ccaccttaac gtcaataagt tccatggctt
    22501 gcagactatc ttttcaggac aatttaacaa tctaacccct tatgtccaag gcatgcgcct
    22561 cgtcaaatca gctgatgaaa tcaataaaat gatgattgcc gggcagttcg ctgataaggc
    22621 tgttcaagtt ggttttgaca atatttcctt agatgctacc gaaacagacg tcatcgctca
    22681 aattgagttt gaaatgaaaa aacaaggcat tcataaaatg agctttgaca ctatggtctt
    22741 aactggaaat aatgcagcca atccccatgg cattcctgga acaaataaca ttgaaaacaa
    22801 tgccctactt ctctttgact taggtgttga gaccttaggc tacaccagtg atatgaccag
    22861 aactgtggct gttggtcagc cagaccaatt taaaatcgat atctacaatc tctgcctaga
    22921 ggcacaacta gcggctattg actttatcaa accaggtgta acagctgctc aagtagatgc
    22981 tgctgctcgt caagtgattg aaaaggctgg atatggtgag tacttcaacc accgcttggg
    23041 acatggtatc ggcatggatg tccacgaatt tccctccatt atggctggca atgacttggt
    23101 ccttgaagaa ggtatgtgct tctctgttga acctggtatt tacattccag gaaaggtcgg
    23161 tgtgcgcatc gaagactgtg gccatgtcac taaaaatggc tttgaagtct ttacccatac
    23221 tccaaaagag ttgctttatt ttgaaggcta agcctctacc atctggttaa acaaaccctc
    23281 gcgaaaggaa ggtattcgta tggatcaaac cattcatcac caaatacagc aagcactaca
    23341 ctttagaaca gccgttcgtg tttataagga agaaaagatt tctgatgagg atttagccct
    23401 tatccttgat gctgcttggt taagcccttc ttctattggc ttagaaggct ggcgctttgt
    23461 cgttttagac aacaagccta ttaaagaaga aatcaagccc tttgcctggg gagcccagta
    23521 tcaactggaa acagctagtc actttattct tttaatagcc gaaaaacatg caagatacga
    23581 tagccctgct atcaaaaata gccttttacg gcgtggtatc aaagaaggtg atggtctcaa
    23641 cagccgccta aaactctatg aatctttcca aaaagaggac atggatatgg cagataatcc
    23701 tcgggcactc tttgattgga cagctaaaca aacctatatc gctcttggta atatgatgat
    23761 gacagctgct cttttgggca ttgatacttg ccctattgaa ggctttcatt atgataaggt
    23821 caatcatatc ctagctaagc ataatgtgat tgatttagaa aaagaaggca ttgctagcat
    23881 gttatcccta ggctatcgtt tgcgagatcc caaacatgct caagttcgta agcctaaaga
    23941 agaagtgatt tcagtcgtta aataaggaga ttaaaatgaa agcattacat acctgtatcc
    24001 gcgtcaaaga ccttgaccag tcggttgctt tttacacaag tgccttccct tttaaggaaa
    24061 actatcgtaa agattttcca gatagtcaat ttactcttgt ttatctggct ttagaaggag
    24121 aaagttatga attagaatta acctacaatt atggtcatgg cgactacgac ttaggaaatg
    24181 gctatggtca tattgccctt ggctctgaac attttgaagc agaccataaa aaacatcgac
    24241 aagcaggttt tccagttacc gatatcaaag aactggctga caaatctgcc cgctattatt
    24301 tcattcagga tccagatggc tacaaaattg aagtcattga tttaaacaac taatactatt
    24361 aacaacagaa gctttaaagc ttctgttgtt ttatttttta acctgacgat tgggacaatc
    24421 tcattattaa cagagttttg aaatatctca gcttttgtgt tacaattgcc ctaaaattcc
    24481 atttgaaaga aaagtctatg acactactat ctatcattgt cccctgcttt aatgaagaag
    24541 caaacattct cccttatttt gaagaaatgc atcaactaga aacgtccatg accaaccaac
    24601 ttgcttttga atacattttt attgatgatg gttctaagga taacaccttg ggtattttgc
    24661 gtgagctagc tgctcgcttt ccaaatgtgc attatctgtc tttttcacgc cattttggca
    24721 aggaagctgg gctcttagct ggactaaaag aagccaaagg caattacatt actgtgatgg
    24781 atgtggatct gcaagatcca cccgaacttt tgccaattat gtacgctaag ctaaaagaag
    24841 gttatgacat cgttggcacc aggcgccaaa atagacaagg agaaccacta attcgttcaa
    24901 tgtgttcgaa tctattttat ggactgatca aacacttatc agatactgaa atggtcaatg
    24961 gagttcggga ttatcggtta atgaccagac aagtcgttga tagcattctt gagttgggag
    25021 aggttaatcg tttttcaaaa gggatctttt cgtgggttgg ttatcgtatc acctatctta
    25081 gttttgaaaa ccaaaaacgc aaatatggaa aaagtcgttg gcatttttgg gagttgctcc
    25141 gatattcttt agatggcttt atcaactttt cagaaatgcc gttaaccatt gctacctgga
    25201 cagggacttt cagctttttg atttctattt tcgccatctt atttatcatt atcagaaaga
    25261 tactctttgg tgatcctgtc tctggttggg ccagcactgt ctctattatt ttattcatgg
    25321 gaggcattca gctcttttgc atgggtatta ttggaaaata tatttcaaaa atattccttg
    25381 aaactaaaaa aaggcctctc tatattatca aagaaaaaca ttaaattaaa acatttttct
    25441 catcaatcgt ttcctactcc ttctgtgcgc gaagctttct ttttaagccc gttataccaa
    25501 atgataatga cctttccaaa atagtatcac cctccttaac actttaagta gaaaaggaac
    25561 tattaggttg agcctttttg caaatcctag cgactaatgt tataatcgtc atactattga
    25621 aaaaggagtt ctttatggag tggattaaat taatcggtat tgtgattatc gtattagggt
    25681 ttattttaaa atgtgatgct atcgctaccg tagttgttgc aggacttgtt accgcgctgg
    25741 tttcaggaat ttcgtttatt gattttctag atattttagg aaaagaattt accaatcaac
    25801 gtttgctaac cattttcttc atcactttac cgcttatcgg cttgtcagaa acttatgggc
    25861 tgaaacaccg agctactcag ttgattcaac gtgttcaagc ccttaccgtc ggccgtttat
    25921 tgactctcta ccttattatt cgagaattag caggtctctt ttcgattcga ctagggggac
    25981 atccacagtt cgttcgaccc ttgattcaac ctatgggaga agctgctgct aaagccaaca
    26041 ttggagaaga gttgaccgat gcagaaaaag atgacatcaa agctatggca gctgccaatg
    26101 aaaactttgg caatttcttt gcccaaaata cctttgttgg cgcaggaggt gtcctactta
    26161 tcgctggaac tttagaacag cttggctatg atggtaacca agctaaaatt gcattttcgt
    26221 ctattttaat tgctattatc tctattatta tagttgctat ttacaattac ctctttgaga
    26281 aaaaaatgga acgtcaacat cagaaaggag ataactaatg gctaacattg caaaccttgt
    26341 tttagaaacg atatatatcc ttatcggctt gcaactgttt cacacagcct actgcacctt
    26401 taaagataaa accaaccctg tctattttgg gacagctctg ttctggggat tgctgggtgt
    26461 taccttcgtt ggcggtgcct ttttgcctaa taaagttatc ggttttatcg tgattgtcct
    26521 agctctttta accttgttta agcaagttcg tattggaaca ttaccagcct ttaatgaaca
    26581 aaaagctgaa gaaagtgctc accgcattgg taactggatt ttcttaccag ttatgttaat
    26641 ggctatgatt tctctacttc ttgccttgat ccttcctgat ttcagtaaaa gtgccattgg
    26701 gattgctggt atcttagcca ctattgctat tttaataatc actaagcaaa aaccatctgc
    26761 tcttttagct gaaaataatc ggatgaacca acaagtgtcc acaagcggta ttttgccaca
    26821 gctcttagga gctttaggag ctatttttgc agctgctggt gttggtgatg tgattgcttc
    26881 tctcattcgg gagattgtac ctgctgatag ccgcttcttt ggcgttctcg cttatgtgct
    26941 tggcatggtt atttttacta tgattatggg aaacgctttt gctgccttta ccgttattac
    27001 aaccggtatc ggtgttcctt ttgtttttgc tttaggagct gaccctatta ttgccggtgc
    27061 tttagctatg actgctggtt tttgtggtac cttattaaca ccaatggcag caaactttaa
    27121 tgccttgcct gttgctttga tggagatcaa agatcgaaat gcagttatca aaaagcaagc
    27181 tcctatcgcc cttgttttaa ttattagtca cattgcctta atgtatttac ttgcttatta
    27241 ttaacttttt tgctaagtta gtagcgtcag ttattcattg aaaggacatt attatgaaaa
    27301 ttcttgtaac aggctttgat ccctttggcg gcgaagctat taatcctgcc cttgaagcta
    27361 tcaagaaatt gccagcaacc attcatggag cagaaatcaa atgtattgaa gttccaacgg
    27421 tttttcaaaa atctgccgat gtgctccagc agcatatcga aagctttcaa cctgatgcag
    27481 tcctttgtat tgggcaagct ggtggccgga ctggactaac gccagaacgc gttgccatta
    27541 atcaagacga tgctcgcatt cctgataacg aagggaatca gcctattgat acacctattc
    27601 gtgcagatgg taaagcagct tatttttcaa ccttgccaat caaagcgatg gttgctgcca
    27661 ttcatcaggc tggacttcct gcttctgttt ctaatacagc tggtaccttt gtttgcaatc
    27721 atttgatgta tcaagccctt tacttagtgg ataaatattg tccaaatgcc aaagctgggt
    27781 ttatgcatat tccctttatg atggaacagg ttgttgataa acctaataca gctgccatga
    27841 acctcgatga tattacaaga ggaattgagg ctgctatttt tgccattgtc gatttcaaag
    27901 atcgttccga tttaaaacgt gtagggggcg ctactcactg actgtgacgc tactaaacct
    27961 attttaaaaa aacagagata tgaactaact ctgttttttt gtgctaaaaa tgaaagacct
    28021 agggaaactt ttcatcggtc tttctcaatt gtcatcttaa tctaatacta cttctaacat
    28081 cagcgggtat agtttgccag taattaagaa acgttgttga tctaaatgag caatcccatt
    28141 caaaacatta aggtcagggt aatgggactt atcaagattt aaggctttta acaaaggact
    28201 aatatcatag gtggctacca cctttccaga atcaggttgg agtttgacaa tagtattggt
    28261 ttgccaaata ttggcataga gataaccatc tacatactct aattcgttaa gcattgagat
    28321 ggggacactt tctatagcaa ctagtacggt atccaataaa gcaaaatctt tggggtctcg
    28381 cttttgcaaa aaagcatttc cactagtcat ccaaagacac tggttttcct tatcataggc
    28441 taatccccag ccatctcctt caaatggata ggcccctaaa caattgcagg tagccttatc
    28501 aaacttgtag gctacaccct ctttataggt tagtaaccaa aaataatcct caacaactgt
    28561 tagcccttct gcaaaaactg tatctggaaa agctattttt tctgaaaaga tctcttgagt
    28621 aaggtcatac acccctactt ttgagaaacc ataacgaccg gcactaagta atatatgatt
    28681 gttgttgagt tgttctaatc cctgcgtgta taagttgcta tcataagaat aagttcgtaa
    28741 caaacgaact tgtcctttag ttatcataat actcattcac cttaccttgc attgtagtgt
    28801 ttcatttgtt ttttaatatc tctttcctga tcacggcgtt taatggtttc gcgtttgtca
    28861 tactcgtgtt tccctttagc tagaccaatc agaactttag caaagccatc cttgaggtaa
    28921 actttgagag gaactaaggt catgccagat cctttaagtt catttgctag atgcgtaatc
    28981 tcacgttttt tgagcagcag tttgcgggtt cgttcaggat cagcgttcca aatattacct
    29041 tgttcaaaag gtgcaatatg cacgttgacc aaccacgctt ccccattctt aatttgggca
    29101 aagccatctt tcagttgaat acgagctgca cgaacacttt taatctcagt tcccgttaag
    29161 acaatccctg cttcaacggt ttcaacaatg tgataatcat gtctagcctt tttattttgc
    29221 gccagtatat gaccttcacc ttttgccata gttaactcct tttacgactc ttcttttttg
    29281 cttgttcttt gtaaaatggt tttttagacc cttttttagt tttacccttg gtttttgcct
    29341 tggctacttc tttaggttct tttttctttg tccctttaga tgattttgag gatttacggc
    29401 gatctcgtcg actagcttta tccgacatct tgattttttc aaccacatca aagtcgctag
    29461 gtaaatactc aaagtcaatg tcaccagttt ccttgtcagc cttaaccaat ttcacacgaa
    29521 taggttgacc gaccttaaag accttacctg atttttcacc ttgaaggctt agcgttcttt
    29581 cattaaagtg atagtattcc ggtaagctag tgatatgaac caaaccttca atcgtatttg
    29641 gcaattctac aaaaaaacca aatttaacga cactggaaac gataccgtca aattcttcgc
    29701 cgacatactc tgccatatac tcagcttttt tcatggcttc aaccacgcgt tcagcatcaa
    29761 tagcacgacg ctctaactgt gaagaagatg ttgctaattc tggaatgatc tgagcaaaat
    29821 ggtcgcgctt ttcttgacta ggttgattgt actcacgaac catgcggtga accaataagt
    29881 cagggtaacg acgaatcgga ctggtaaagt gagtgtaata ttctgcggcc aaaccgtaat
    29941 ggccatgatt atgttcagaa tacctcgctt gttgcatgga acgtagaagc atcatgttga
    30001 gcacttctgc tcctggttga ccttcgactt ttgccataaa ggcttgcaag gcttcctgag
    30061 aaatcttgtt ggctgttcct tgaatgtgaa taccaaaggt gctagcgtaa tcaataaatt
    30121 gttgaagttt ttcggccttt ggttcttcgt gaatacggta gataaacggt aacttagctt
    30181 ttgcaaaatg ctccgcaaca cactcattgg ctgctagcat aaaggattca atcatccgct
    30241 ccgcaatgcc cctttgacga agcaccacat caaccggcat tcctttgtca ttaacaataa
    30301 tttttgcttc ttgcgtatca aaattcaagg cgcctcgttt tgaccgcata gcttccaaaa
    30361 tcctatgcaa agccaccatg agggtcacat catcagcaat gctagcgaat tcttggagcg
    30421 cttcttcatc tcctgcaatc atgtcattga ccgtactata cgtcattcgg taagttgtct
    30481 taatcactga ttgacagatt tgataattga ccacatgccc ttgagaatta atttccatca
    30541 aggctgactg ggtcaaacga tcaatgttag ggttcaaaga gcagatgcca tttgacaaac
    30601 gctctggtaa catcggaacc acacgatcgg tgacatagac agaagtgcca cgggcgatag
    30661 cttccttatc aagggcagat ccttctgtca cataatatga gacatccgca atatgtaccc
    30721 caagttcata attcccgtta tccaatagct taatatggat agcatcatct aagtctttgg
    30781 cgtccgcacc atcaatagta atggtggttt cttgacgcaa atccacacgg cctattaaat
    30841 ctttagcagt tggtgcttct gaaatagcat tggcctcagc taaaacttct gctggaaatt
    30901 ctgacacgat atccatcgat tcaaggactt ctaggacatc aattccaacg tctccttgat
    30961 ggcctacgat atcacgcaca ctggctacaa aataatcgtg cccgcgtatc gggtatttat
    31021 caatatcaac cttgatgatt tcagtgcctt taagcacaac aggttctttt ttgatataga
    31081 ttttttgttg aatcttttgg tttttggacc tgatataacc agcatatttt ggtttgtcat
    31141 catctaaaac aaaggttcca acagctgttt ttaaagaacg gtcaacaata gcaacgacct
    31201 tagcttcagc cgctgtgcct ttgagacggt ctgctggctt tttaaccact acttcgacag
    31261 tatcaccatc aatagcatac ccaacatcat tacgaccgat aaacatgtca tcttcattct
    31321 catccacatg taagaaacca aagcctgctt tattggcacg aaaaacaccc tgaacagtag
    31381 gttctttttt cttttcacgc tcttttctaa gagccagact gccatcatct gaaaaccgta
    31441 acaggctctg actttccatt ttggaaatgg ttttaataag gctgggaaaa tgcttagctc
    31501 cagccatctc caaggccgca gccaagtcgt tcacattgga cttgccatgc tccttgaggt
    31561 aagtcataat tctttctttc atcataccta atttctattt ctgttttgtt tgttggagga
    31621 tatcaatccg tttcgctgat aaaaaaatga gctagactaa ctctgtcaag ctcactcctt
    31681 atttacttga taaaatggca agcacaagtg caatcgctag ccaaaaaaat actagaactg
    31741 ctgtgaatcg ttgcatgaat gcttcaaagc cacgagcttt tgtacgttca aacaaggctt
    31801 ctgaaccgct gctatcaaaa acattgctac ttgggttttt ttgaggttgc ataaaaatag
    31861 caatcacaag caataccgac agtactagca atatcgtaag tagtaagttg tacatgttat
    31921 ttcctccact attgtcatga ccattctaac acaattctta tcaagtttca acatgcaggg
    31981 tcacttttct ctccttgggg cagtatttgg gaacttttat tttttccgga tgactgcttt
    32041 tatttttact ggttagataa ttgttactgc cacactcact acattctaaa ttaattttta
    32101 ctctcacaca atatccttaa ctttaatata ttttcgaaat ataatcaaac tccatattaa
    32161 attaacaaac acaatcaaac tagtcacata aaaaacagaa cggtagccta acactacagc
    32221 cacatttgat ccaataaaag ggccaatgac ttgaccaagg ttactaaaca tttgattata
    32281 ggcaaatact ctagaaatac cttcttttgg tgttaactta gttagtaaag agttaatact
    32341 tggcatcaaa gcgcccacac caaacccata agcaaagcgt agtactccta attgaaaact
    32401 ggtctgcgct aaggcactgc taaaatacat gataaagcta taacacaaag cggctaacaa
    32461 taaccgatga ttgccaaatc gatctcctaa ttttcctaag taagaactgc taaataagct
    32521 agaaaacccc atggccgaaa ctaccaggcc tgaagtaaac attaagttgt gagtttgacc
    32581 aagatgacga atatacaatg ataaaatggg ggccactgat tgagctgaaa tttgaataat
    32641 catactagtc acaaataaac caagcataat ctggggactt tttacctgtt ttaaaatgac
    32701 ttttgtaggt atcatctcaa agcgcctaac cggcttaaac tcttctttaa cataaacagc
    32761 tgtcattaaa gaacataaaa ataatatcac accaactaat aagaaaactt gtcgaattcc
    32821 taatagctct gccaaaattc cccctagtaa aggaccaatt aaagcgcctg ctgtcactcc
    32881 tgttgctaat gtgcctaaag cataacctga ctcctctttt ggggcttggc tggcaatcaa
    32941 ggcagtggca tttggcacat agcccgcaaa gacacctgtt aataatctca aaatgagtaa
    33001 ccaaaacaca ttaggaataa tagctaaacc acccattgta aatgtcataa caaaactggc
    33061 tcgcagcatc ataggttttc ggccataacg atcagccaac ttcccccaaa caggagcaaa
    33121 taaagctgaa gcaagtgccg tcacagcaac tgccagacca gcatagtatt ctactaattc
    33181 tgtcggagta cctaaatttt ccacatatag agccataaaa ggcataacaa gtgaaaagct
    33241 tgccccagta aagaagttac caagccaagc cacttttaga ttttgtcgcc agttcactgt
    33301 cgttaccgct ttatcactaa tagatcatca tcttctttcc attgggcctt tgattattat
    33361 aacacatttc tgccaaaaac agtgtcccat aatagtgcta agtctcatct gatagccttc
    33421 atcgtttacg taaactaccc agtaaacctc tgaccagttc tcgcccaatt gttctaaccg
    33481 tcgtactaat aaacgcatct gttgcttttt cgacgactgt tttgtgggaa cgcccaacag
    33541 aacgccgatt agcttttttg gtagctgctt gcgccttgat ggcttcttta gcttcttttt
    33601 cgcgttgtgc tgtcgctatc gcttcttggg ccagtcggtt gtcttctaaa accttagcag
    33661 ctaatttttc ataagcagat tcacggtcaa tggactgact atatttactg gcaaaaggtg
    33721 aggactgcac aagctgctga ctctctatct ctgacaaaac agcaaagcta ctcttaggcg
    33781 gcatgatata ggcacgttca acgatggatg gttgtccctt atcattcaaa acagaaatca
    33841 aggcctcacc gacttctagt tctgtaatca cccttgccac atctaagtca ggattttgtc
    33901 ggaaagtatc cgcagcgaca cgaaccgcct tttgttcttt cggtgtataa gcgcgaaagg
    33961 catgctgaat acgatttcca agctgagcca aaaccgtttc tggcaaatca agtgggtttt
    34021 gagtcacaaa gaaaatccca actccctttg aacgaataag tcgcacaatc tgttcaactt
    34081 tttccaagaa aactttaggg gcatctttga agagcaagtg agcttcatca aaaaagaaaa
    34141 ccatcttagg tttgtccaaa tccccaactt ctggcaataa tttgtacagc tctgataata
    34201 accaaagtaa gaaggttgtg taaagggtag gagattgaaa aagcttagtc gctgacaaaa
    34261 tgttaatggc tccataaccc gaagcaacat ctaattgcat caaatcagcc acatctaaag
    34321 caggctctcc aaaaaattgg tgggcccctt cttgttccaa agtcaagaga cttctttgga
    34381 tagccccgat agattgctta gcgatattac cgtaatggct ggagtagtct gaggcatggt
    34441 caccaacttc ttttaagata gcctgcaagt ctttcaaatc aatcaaaagc caacctttct
    34501 cgtcggcgat tttaaagacg atgtttaaga cacctgtctg ggtatcatta agattcaata
    34561 aacgcgacaa catcataggt cccagctcag aaatcgttgt ccgtaagggt tgaccgtttt
    34621 gaccaaaaac atcccacatt cttacaggaa aggcctgagg ctggtaatca cttaccccga
    34681 ttgtggctaa acgcgcagcc aatttatcag tcacctctcc tgctttagta agattagaca
    34741 ggtctccttt gatatctgcc aaaaagactg gcacaccagc taaacttaat tgctctgcta
    34801 gcacttttaa ggtcacagtt ttacctgttc cagtcgctcc agcaatcaaa ccgtgacgat
    34861 ttagcatccc taattgtaag gctatcggtt gattgccttt tgcaattgtc attgtagtca
    34921 taggcttcct cttttttgat gatcatactt atcgatatgt gtttacccat aagttaaagt
    34981 gtttagaagg gtctcactct taatactatt ataacatata acccttgatg cgctaattta
    35041 aaagggacca gctagtttta gacagaaata gcttgatttt gacagctatg atacgaatct
    35101 ctcagcttag ctacctcgga ttggctaata acaacaacgc agattgtact tgctttatta
    35161 aggctgcaat atccccacta ttatcaatca ctagactggc atagggcttt ttttcctcta
    35221 ttggtaactg actggctatt cgctgccttg cttttccttt gtctaaacga tttctagcca
    35281 ttaagcgctg caattgtgtc tgagcatcta cataaaccag ccaaatcgca tcaaaccagt
    35341 cttggtagcc caattccatt aaaaggggaa tatccatgaa aaaaatggct tggctctgtg
    35401 ctaagtggtc acgcttagcc gccaattctt ccttaatgat ttgattttga atggctgagg
    35461 atgttgccat attatctggg tttgaaaaaa gcatttctga cagctttgtg cgatctaact
    35521 caccatctgc ttttaaaatc tgattcccaa aagcttctct aagagcctcg taaagacgac
    35581 cgcctttttc ttgcaagtca tgaaccactt gatccgcatc aatcacctga taaccagctt
    35641 ttctaatgac cttaaccaca gtcgattttc ctgatgcaat gcctcctgtg atgccaataa
    35701 tcatagtctt tttttctggc attttggaca aatgtgcgtc ccccttcctc caacttttaa
    35761 tttgacaata gcctgtccac aacgaggaca cggtttccca gtttgaccat aaacctgcaa
    35821 atagtcctgc atggtgccat cagctcccaa agcattacgg taagtacgga cggtcgaacc
    35881 gcccttttca attcctaaag ctaggattcg tatggtttca tcatgcagcc gttttatctc
    35941 cgccttattc aacctagaag acgcagtttc tggatgaacc ttagcagccc aaagtacctc
    36001 gtccacataa atattcccta aaccagcaac caaggtctgg tctaaaagat gtggttttat
    36061 gggtttttgg gaggatagca gagcagcctc aaaggttttt aacttaaagg tctctttctt
    36121 tggttcaggg cctagttttc gtttggcaaa aaacgctgat aattgagatt ttgctatcaa
    36181 atcaaaggtt ccaaatttac gcacatcttg gtaaaccaag gtcgaaccat ttttcaattc
    36241 aaaaaagaca tgaaagtgtt tgttatcagg gacctcatct ggaaaaagca aatatttgcc
    36301 ttccatccgc aaatgtgata ccaacactaa ttgccccaaa tcaattaata aatattttcc
    36361 ccgacggcca actgactgaa tgatttgacc aggtagggtc agggcaaacg tctctaagtc
    36421 ggttttaacc atttttggca ctttaagcgt aacagccaca atttcttggc caagcactaa
    36481 agtctcaagt cctcgtcgga ccgtttcaac ttctggtaat tctggcataa tccgttattt
    36541 aaaggacagc tagacccttt gctcctacaa agaataaact cagtataaaa aagtcactca
    36601 atagactcag gtctaggcta ctgactgcgt ttcaaaaaac acagctgtcc ttctcctttc
    36661 ttatttctta ttttacgaac acatctgata gaaagcaact cataaatctg cctcagacca
    36721 gtcctcatcc cccttacctc ccagcactat ttgacggtaa tgttccttat aactataata
    36781 caatgagtcc tctccaagat acttaaaaat ctgcaaggcc tgccgcatgt cctcttctcc
    36841 agacatttct tcctgcttta atttataata cccatgcaca tataagaaaa cagtcttttc
    36901 ataaaaattg agctcgtctc gcagcaaaag atcaattttg ttaatcaaat agcgactatg
    36961 ttcaaagcaa gaatggtcaa tactgataat gagacaatta atggataact gagtcactaa
    37021 cattttattg gttttatttt gttccgaata agcaaaagat gctaccattt ccttagtcaa
    37081 taaaaatagg gtattgtaat tcatgaagcg cgagcaattc cccagaagaa tgatttcata
    37141 atatccccac tgttccactt taaataaata atctgtgagg cgagtcaatt cttcttgact
    37201 aggtgcaatt gaggagtcaa tagaaaaaag aatagcttta atcatcgttc gttcataatc
    37261 tttatgggca taatccttca acagtttggt caatttaacc acgtttttct cagcataaca
    37321 ttttctcgcc tgacttaaga gcgtgaaaaa atgcgtatgc gtcttggaat gagccgaaac
    37381 aaattcgtca atcgtaatat tcagtttatc caaaagatta agcaagcgac tgcaggtgat
    37441 ttctgattcc cctcgttcaa atcttgaaat ttgtgacttg gacaggtatt catctgctaa
    37501 aaaagaaatg ctaacctgct tacccttacg taatcgcctt aaggtttttc cgagttcttt
    37561 ttccattttt cccactttca caacaaaaaa ttaaaatctg ctaaatccat tatataatac
    37621 aagtacaaaa tagaaaatca gaaaggagac agtcatgaaa aaagttaata aagctttgct
    37681 ttttacattg atcatggata tcctgattat cgttggtgga taacctttcg cttaaaaaca
    37741 atccactttt gggaaaccct tatatttagt ttgtaacagg aaaactaata aatattaaaa
    37801 agagtgttag cgacctagcg gcagctttac tcttaagtgc gtttgctgcc attgacagca
    37861 aggtcaaggc tgatgaaaca gcaggggcat accgttatga tgtgtctgga caaaacactt
    37921 actatcaaac tatcagctcc attaaccagc aacgacctgg tgccactctc gacgaatgag
    37981 gtgattatta tggaaccctt acttcattta cttcccaaag tcgtaccagt acttatacac
    38041 ttggtagaca aagccaacgt atcatggtta acagtgatat tacagttacc tatactctta
    38101 aagacaattt ggtagccctt cataaggaat ataaaacctt tgtcaaaaaa atattacaga
    38161 taaaccgatc accagtgact acgacaaggc taaggttatt tataaccatt taatcaacga
    38221 atacacttac gccacaaaat aacttagcac caattgcaaa accgtaagca gcatcaacaa
    38281 tcatactcct aaagctcttt atcgtgacaa gtgtggtgtt tgtcaagctt atgccgtcat
    38341 gtttaaagat atggcagaag ctgcaggctt atcagcttgg tatgtgataa aaaaggattg
    38401 aatgagcacc atgcttgaaa catcgttacc attcatggtg ttaattccta cgttgatgct
    38461 acctggaatg attcagcata caccacaagg tatttccttg ctggaaaaga cgtgaggaat
    38521 actgagtacc gtttagatag ccagtacaac cacttggcta atgctatttt aaataccagc
    38581 taccaaaaag gctaaactaa caacaactac atttttcaaa tagaaaggcc taaacaatga
    38641 ccaaaaaaca gttttatctt atcttagcta ttagcatact gtgttttatt cttgccgtca
    38701 gccctaaacc accaattctt aaacacacta ttgaaaggaa aaggactgcg atgaccatag
    38761 gccactcaaa acaaaaccct cacaaaaaag aagcccttaa acacaaaaaa aacaaaaata
    38821 aggctctttt tcttccaagt ggggacagcg ctatcaaatc tgttattagc atgacagtta
    38881 gactcctgtt agatgaccaa tcttagctct cctaaaatca gtggacacta ccatttcggt
    38941 agtgttcttt tttaagctaa tctcatcacc acgctttctt caagctaaaa aactgatcat
    39001 gaaagagcaa ccccatcacc ctaacagccc actttgcccg cactttctta aaaagttagg
    39061 agaaaacgat ataccaatta ttttctgatc ccagctccct atcattaaca agatgtgtag
    39121 cacggaccta catacaggta agctagagtc attctcgcta tttcggacaa aaagaggccg
    39181 gtagttccct gacctcttct ttatttatct tgtaacactc ctcttcttag cgagacttac
    39241 tagcacataa ttcttaagca ctcttatcat ttagactagg aataacacca tctgaatgaa
    39301 gcaaatgatg cgtcagatct gccagagtat catctccata agtaatccct gtttggtgct
    39361 gtttctgatg aaaatcagat gactccttaa ctttagcagt cacctgctgg tcacttggat
    39421 gaaaattaat ttctctcttg gcttcagccg caactggctc gaggaacaac ttattgacat
    39481 cacggtcttc ctccaaatga ttaaggatag cagcatcatc ttctaacgaa agaaccttct
    39541 tgggtaacaa aaaggggtta tttagccttg gctcagtaac gacttccttg gctactcgtg
    39601 atagtttatt attgtcttcc tcaggtatca aacggttagg caatcgatgc aattcttccg
    39661 gctgtgaggc gctcacagct acttcagaag aaacctccaa gccctttcct gtttgcctgt
    39721 ctaaagcaac cggcaaatta ttaactaact ttttaacctg tcctcagcgc tcatttcaac
    39781 actaggaaga gctgtcgctg gttctagcca gctaccaact tctgctggtc ttaccttaac
    39841 atcgctggca ggcttctcct tctcatcttc attaggtcta aaaggctcaa accgccctgt
    39901 tgatttttca tctatgacct ttatattgtc ttttactaca tgagacagtg gttcgacatt
    39961 taccatagct tcatgctcgt taaggctctg gtctcgtttg aatttaccag gaataccagg
    40021 agtcggtgtt ccgacagatt gatcggcttc agtaggctct tttacggagc cttttttcca
    40081 taaaactgct ggaggaataa tatccgtaga gccgtcccca taagtaatcg tggcctgcct
    40141 cccctttgga ttaatagata ctttaatatt gtctgggaaa gccccactac ctcctgtggt
    40201 taaaagggca cccgcatttt taatgagagt tgtcattcgt tcaataccag caacgccaat
    40261 atggttcaag tcatctactg gtaactgatc aacagatttc atggtgtatt tccaagcttg
    40321 cggttgaaca agaaaaacag ttcctttata cattgtgtta tgcatatcat caatgacttt
    40381 gaaatacctt atatatttgg tttgtacatt agggttagca acgggaacag tgctttcagg
    40441 aactcctgac atcgtaaaaa tccctctagc agaagtttga aagccctcat aaacatgacc
    40501 cataccagga acaatctgag cggtcaaaga cttatcagaa ccatccaaag caatgcgaat
    40561 atctttcatc agagacatct gattggtata ggcaaaccta accgtgttag cctcacctcg
    40621 atacaaaacc acttgggagg gctgatccga agaaaactga gaggttgttt cttccttata
    40681 gccaactcca aaagccaact ccaaaacgtc tatcagacga atggactgaa tctgccgcaa
    40741 ctgtactact caaactgact agtaaagtag ccgcacaacc aactaataaa ctgctcgttt
    40801 taactttaac atctcttaac atcatcatgt tcctttcatt attttttatt taggaattcg
    40861 acatactata ttttctcata ttagtctaac aaaaaactcg taattctata taaatcatat
    40921 aaaatgacga gctttggcaa agatgagtat agcaggatgg aaaacagatt atttctgaaa
    40981 cttcaaaggt atcttcttgt cacgaactat tctttaattg aatcggt
//
LOCUS       DAUGQX010000014        40385 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUGQX010000014 DAUGQX010000000
VERSION     DAUGQX010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40385
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.014"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(130..2115)
                     /gene="tkt"
                     /locus_tag="VIA51_000651"
     CDS             complement(130..2115)
                     /gene="tkt"
                     /locus_tag="VIA51_000651"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEQ8682608.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLSKGAYILSEAKGDLDGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     SGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(2333..2977)
                     /gene="fsa"
                     /locus_tag="VIA51_000652"
     CDS             complement(2333..2977)
                     /gene="fsa"
                     /locus_tag="VIA51_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8682609.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(3103..4602)
                     /locus_tag="VIA51_000653"
     CDS             complement(3103..4602)
                     /locus_tag="VIA51_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8682610.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMDQETDFSQQLSDDVLALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(4592..5938)
                     /locus_tag="VIA51_000654"
     CDS             complement(4592..5938)
                     /locus_tag="VIA51_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8682611.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFDYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDADLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(6046..6747)
                     /locus_tag="VIA51_000655"
     CDS             complement(6046..6747)
                     /locus_tag="VIA51_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8682612.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAAFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAVLAVLLFQVMS"
     gene            complement(6749..8587)
                     /gene="glpO"
                     /locus_tag="VIA51_000656"
     CDS             complement(6749..8587)
                     /gene="glpO"
                     /locus_tag="VIA51_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEQ8682613.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFERDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGHQEG"
     gene            complement(8603..10129)
                     /gene="glpK"
                     /locus_tag="VIA51_000657"
     CDS             complement(8603..10129)
                     /gene="glpK"
                     /locus_tag="VIA51_000657"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEQ8682614.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            complement(10490..10882)
                     /locus_tag="VIA51_000658"
     CDS             complement(10490..10882)
                     /locus_tag="VIA51_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEQ8682615.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(11009..11266)
                     /locus_tag="VIA51_000659"
     CDS             complement(11009..11266)
                     /locus_tag="VIA51_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEQ8682616.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(11420..13459)
                     /locus_tag="VIA51_000660"
     CDS             complement(11420..13459)
                     /locus_tag="VIA51_000660"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEQ8682617.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGSFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGAV
                     LALAAKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYANKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAAAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAGDQALKNNRLAILSDLVSKAKTIVAFNQLNTK"
     gene            complement(13837..14754)
                     /gene="glyQ"
                     /locus_tag="VIA51_000661"
     CDS             complement(13837..14754)
                     /gene="glyQ"
                     /locus_tag="VIA51_000661"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8682618.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            complement(15126..15659)
                     /locus_tag="VIA51_000662"
     CDS             complement(15126..15659)
                     /locus_tag="VIA51_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEQ8682619.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(15791..16630)
                     /locus_tag="VIA51_000663"
     CDS             complement(15791..16630)
                     /locus_tag="VIA51_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEQ8682620.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSAIPTPDT
                     TSF"
     gene            complement(16752..17900)
                     /gene="nagA"
                     /locus_tag="VIA51_000664"
     CDS             complement(16752..17900)
                     /gene="nagA"
                     /locus_tag="VIA51_000664"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEQ8682621.1"
                     /translation="MTCYLKADCFYYPTEVRPAGYLSLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(18018..19649)
                     /locus_tag="VIA51_000665"
     CDS             complement(18018..19649)
                     /locus_tag="VIA51_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEQ8682622.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADGKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            19851..20573
                     /locus_tag="VIA51_000666"
     CDS             19851..20573
                     /locus_tag="VIA51_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682623.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(20702..21544)
                     /locus_tag="VIA51_000667"
     CDS             complement(20702..21544)
                     /locus_tag="VIA51_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8682624.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLIKLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            21837..22394
                     /locus_tag="VIA51_000668"
     CDS             21837..22394
                     /locus_tag="VIA51_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8682625.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(22430..23254)
                     /locus_tag="VIA51_000669"
     CDS             complement(22430..23254)
                     /locus_tag="VIA51_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8682626.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALVAQKD"
     gene            complement(23256..23873)
                     /locus_tag="VIA51_000670"
     CDS             complement(23256..23873)
                     /locus_tag="VIA51_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEQ8682627.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLMARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(24070..25047)
                     /gene="lacD"
                     /locus_tag="VIA51_000671"
     CDS             complement(24070..25047)
                     /gene="lacD"
                     /locus_tag="VIA51_000671"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8682628.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(25094..25547)
                     /locus_tag="VIA51_000672"
                     /pseudo
     CDS             complement(25094..25547)
                     /locus_tag="VIA51_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(25557..26072)
                     /gene="lacB"
                     /locus_tag="VIA51_000673"
     CDS             complement(25557..26072)
                     /gene="lacB"
                     /locus_tag="VIA51_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8682629.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(26087..26512)
                     /gene="lacA"
                     /locus_tag="VIA51_000674"
     CDS             complement(26087..26512)
                     /gene="lacA"
                     /locus_tag="VIA51_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8682630.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(26752..28203)
                     /locus_tag="VIA51_000675"
     CDS             complement(26752..28203)
                     /locus_tag="VIA51_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEQ8682631.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYAARNHLPVFVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGPQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            complement(28229..28534)
                     /locus_tag="VIA51_000676"
     CDS             complement(28229..28534)
                     /locus_tag="VIA51_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8682632.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPIVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            complement(28527..29000)
                     /locus_tag="VIA51_000677"
     CDS             complement(28527..29000)
                     /locus_tag="VIA51_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8682633.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            29237..30007
                     /locus_tag="VIA51_000678"
     CDS             29237..30007
                     /locus_tag="VIA51_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8682634.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            complement(30211..30414)
                     /locus_tag="VIA51_000679"
     CDS             complement(30211..30414)
                     /locus_tag="VIA51_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEQ8682635.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLIKRALKDTKFELYKWS"
     gene            complement(30428..32659)
                     /locus_tag="VIA51_000680"
     CDS             complement(30428..32659)
                     /locus_tag="VIA51_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEQ8682636.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGRAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATVVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLT
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNAALMGILGIDLSCVQSVCAKASEKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRVTM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(32659..33093)
                     /locus_tag="VIA51_000681"
     CDS             complement(32659..33093)
                     /locus_tag="VIA51_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEQ8682637.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNFLTSYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLYHL
                     PMTLEEIGAFQELLEVKKENAVLEVPCNCLPGQCHCQRKETY"
     gene            33265..34251
                     /locus_tag="VIA51_000682"
     CDS             33265..34251
                     /locus_tag="VIA51_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8682638.1"
                     /translation="MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEI
                     PEYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTP"
     gene            complement(34385..34735)
                     /gene="rbfA"
                     /locus_tag="VIA51_000683"
     CDS             complement(34385..34735)
                     /gene="rbfA"
                     /locus_tag="VIA51_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEQ8682639.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRDLDNKS"
     gene            complement(34940..37801)
                     /gene="infB"
                     /locus_tag="VIA51_000684"
     CDS             complement(34940..37801)
                     /gene="infB"
                     /locus_tag="VIA51_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEQ8682640.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(37821..38123)
                     /locus_tag="VIA51_000685"
     CDS             complement(37821..38123)
                     /locus_tag="VIA51_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEQ8682641.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            complement(38116..38412)
                     /locus_tag="VIA51_000686"
     CDS             complement(38116..38412)
                     /locus_tag="VIA51_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEQ8682642.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(38428..39585)
                     /gene="nusA"
                     /locus_tag="VIA51_000687"
     CDS             complement(38428..39585)
                     /gene="nusA"
                     /locus_tag="VIA51_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEQ8682643.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATAVEEPVVDDVMTAEEV"
     gene            complement(39760..40296)
                     /gene="rimP"
                     /locus_tag="VIA51_000688"
     CDS             complement(39760..40296)
                     /gene="rimP"
                     /locus_tag="VIA51_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEQ8682644.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
BASE COUNT        11899 a         8987 c         7322 g        12177 t
ORIGIN      
        1 gaatcgtttt gtcaatgact tcttatcaaa agaagtgtat taggcagttt gaggaaaaga
       61 aagaactggg tattttattt taaaaaaaca gagtaaatca aatgatttac tctgtttggg
      121 atgtttaact tagagtgatt tgtataactc agttgcattt gccacagtga aaccatattc
      181 ttcgaagata cgatttcctg gagctgaagc accccaagtg tcaatggtca atgtttttcc
      241 tgataggccg acatattttg cccagccaaa gcttgaacct gcttcgatag cgagacgttt
      301 agtcacagct gctggtagga tgctttcttt atactctgct gactgttcgt caaagatatt
      361 ttgtgatggc atagatacga cacgcacatg aatgccttct gcttcaagag cttcttgagt
      421 atccattgcc agtttcactt ctgaacctgt tgcaatcaag ataccatcaa ggtcgccttt
      481 ggcttctgac aagatataag ctcctttgct aagaccatct tctgccaatt cttttgtgcc
      541 ctcaagcact ggaaggtttt gacgcgtcaa tacaagcatg gttgggcgat ctgtttcagc
      601 aatggcacgt ttccaagcag catttgtttc gttaccgtct gctggacgaa taacgttcaa
      661 gttaggcatt gagcgaacac ttgccaattg ttcaattggt tcgtgcgttg gcccatcttc
      721 accgacagcg atagaatcat gtgtcatgac ataaactgtt ggcaagtttt ggagcgctgc
      781 catacgaaca gctggaagaa gatagtttga gaagacaaag aaggttccgc cgtaaacgcg
      841 tgtcccgccg tgaagggcaa taccgttcat ggctgcagcc atggcaaatt cacgaacgcc
      901 aaaccagatg ttacggcctt cgtagtgacc tggttggaaa tctgtttcag ccttaaccat
      961 agtattgttt gaagctgaaa ggtctgctga cccaccccag aaagaggcta cttgttctga
     1021 aatttgttgg atggcttgtt gactggatac acgactcgcc attgaactac caagttcgtg
     1081 cgcttcaagt tctacttgag cagcttcgtt agtaaaggct ttttggtatt ctgctgctaa
     1141 ttctggatat tctgcttcat aagctgcaaa caagtcattc caggcttgtt ctgctttttc
     1201 accacgcgct tgaagacctt gagcaaagcg ctctgttact tcagcaggca cttcaaaatc
     1261 ttgatgagtc cattggtaag cttttttggc aaaagcaatg ccttctgctc caagaggagc
     1321 gccgtgaaca gctgaagttc cttgtttttc ggcaccaaaa ccaataatgg ttttgacttc
     1381 gatgatggtt ggtttctcag tttcagcttt agctgcttca atagcagctg caatttcttc
     1441 taaatcattt ccatctttca caaggatatg ttgccaacca taagcttcga aacgtccttt
     1501 cacatcttct gtgaaagcca tagaggttgg accatcaaga gagatgtcgt ttgaatcata
     1561 tagcaagacc aatttcccaa gttttaaatg tcctgccata cttgctgctt cttggctgac
     1621 cccttccata aggtcaccgt caccattcaa agcaaatgtg tagtgatcaa cgatgtcaaa
     1681 gcctggtttg ttaaatttag ctgctagatg agcttctgcc atggccatcc caacggcatt
     1741 tgcgatccct tgaccaagag gtcctgtggt tgcttcgaca ccgtctgtgt ggttcacttc
     1801 tgggtgacct ggtgttttag aaccccattg acggaagttc tttaaatctt ctacagataa
     1861 atcataacca gctaagtgta acaagctata aagcatggca cttccatgac ctgctgatag
     1921 gataaaacgg tctctgtttg accaattacg gcttgttttg ggattgatgt tcatgaagtg
     1981 attccaaaga acataggcca taggtgctgc ccccattgga agtcctgggt gtccagaatt
     2041 tgccgcttga atggcatcca ttgatagggt gcggacagtg tttactgcca actggtcaat
     2101 tgcatcaaat gtcataagta aaacctctct gtttattaca actaaaatta aacgttttct
     2161 attgtctatt gtatcacaaa aatagacgct tttttcagaa aatcctccaa agtccctaaa
     2221 ttctttttct ctattttgcc agaaaaaaac tagtttggac atcattgatg gattcttttt
     2281 gacgatgaat ataagagagc ctgttgacac agtggccaca gactctttag ccttattttt
     2341 taaaggaagc ccaatcttcc ataaaggttt tcaaaccatt tgtcgttaag ggatgttgcg
     2401 tcatcttagc aaacaagggg tctggaatcg tcgcaatgtg tgcgcctaat ttagcaacag
     2461 cttccacatg ggctgttgta cgaatacttg ctgcgatgat ttctgcttgg aaatcgtaca
     2521 agtcaatgat ttcacgaagg tcgctgatta attgataagc atctgtgcca atatcttcca
     2581 aacgaccgat aaatgggcta atgtaagttg cgcctgcttt cattgccatt aaaccttggc
     2641 ttactgtgaa aatcaaggtc acattagttt taatcccttc ttttgaaaga atgtttgttg
     2701 cttttaaccc ttctgtagtc attggaattt taacgacgac attgtcatgc cacttagcaa
     2761 tgcttctagc ttcttctacc atagcatctg ctgttagccc tgtcacttca gcactgattg
     2821 ggccatcgac gatgtcacag atttctttga taactgtttc aaaatcacgt ccttcacgtg
     2881 agataatggt tggattggtg gtgacaccat ctacaacgcc aagttcatta atcgctttaa
     2941 tagcggctac attagctgta tctaggaaaa atttcatttc ttacctccaa aaattttcga
     3001 ttttgttaag ctctatttga taagcttttt caaatcatct acctttagac tatcctactt
     3061 tattattata aaagtgtaac agtccttaga aaagaccaag tatcacacag ttttgtgtgc
     3121 aaaactagac ttagctgctg ggctgagtga gagttcctct tctcgtgtat ttttttgctg
     3181 gaaaaggtct ttgagaaaag cttctaaagc agtgagttca tagggggagc tatactgttt
     3241 taaccggtaa tagggtaaat cttgtctcgg taaacagaca gtctgatagg taatcagaca
     3301 atcataaact ttctgatgat catagggcat taattgaaaa tccctacgat gccccaaatg
     3361 acgtctaatg gccaattccg caatggctgc ttccacctta ttttgcccca aggcaagccc
     3421 tactaaaaga ggctcatggt ggcgctcaat ggaaaaaatc aacaatgcta aaacgtcgtc
     3481 actcaactgc tgactgaaat ccgtttcctg atccatttgc agcactaaat ggtttatgat
     3541 aacccttaaa agcgctcttt tatcttcgcc tactaattga taaaggtatt ggctattggt
     3601 tggttgacta aggatagctc ctttaaaaaa gtaagctttg gaaaaaaata tccccaagcc
     3661 ataaatgatt tcctcctttg tctgatggat aatcacatga gccttcttta aaagccataa
     3721 ggcttctgaa atgtgatcag caataggacc tccaaaaccc aaactatact tcatgctggc
     3781 aataggaagt agaggataag catgcaaaaa gacaaagagg ctcttagctt caaaagcatc
     3841 aaattcaagg gcatagcgtc ttaagtaatg taaaagcatg ctttctaagc gcttaaagaa
     3901 aatattagat gtcataaagt cactatctct taaaaaatga tcattgtagc ctttttgaaa
     3961 ggacattcgc gcttgcgaaa tcgccaacca aatcaataat tgttctaagg cttctgccga
     4021 taatgactgg ccaatcagcc gctcaattaa ggtagccaaa tgcgaagcgt ctaactgatt
     4081 gaccaaggcg tctatgcctt gtctggtcaa ggtatggcgg aacaattcaa aatagaaata
     4141 acgccactga agctcacttc ccagttgtct gccttgcgag agcgccagat caaattctga
     4201 taaaagctgg ttgaggtgag ctaattgtct gtttagagta gcttcactaa ccatcagttc
     4261 aacggataag ttggtgatgt taaagtgttc atggcagtac atgtaggtca atatctgata
     4321 ggcaaccgat tctttgagaa gcagagctac caaatcctcc caatggaact ggccattttc
     4381 ttttaagctc agactgtctt tttctaaaag taattgacag gctaaacctt gttctcgaca
     4441 caaatgattt agattgtcaa tgtattttaa tagggtcact ttagacaagt ttgatagcct
     4501 cattaggtct tttagcctta acgtttcttt agcatgataa agggtcacca agagacgata
     4561 ttgggccctt cgttccttat ccattaagtc ttcaatcttc atggcggagc ctcttttcaa
     4621 ataatttgag acaagcttca tgaagatgat aagccaaatc actgtgacct tgtaaaaaga
     4681 gaaaatcttg aaatgctaag tcagcgtctg taactttcag agccagagcc tgacctaatt
     4741 gattggcgat gacaagagca ttggttttgg ataggagctg agcgcctatt aaaatcccat
     4801 ccgtttttct agctattaat ttcagccaaa agaggttttt agaatcccca ttttggtaca
     4861 aatagctaca cgtatccata taaagctctg cttcttcttc tgtcacacca acactcgcgc
     4921 gataataatc aaagtgagaa cttcctaata ccttgaccgt ctgtaatgga ggaataggat
     4981 atccagctaa atgcagagcc agagcctgac ctgtcttcat tgcttggtta atcaaaggtg
     5041 tatagtaatc cattcccaat ataccaaaat gcaatgaaac catgtctcca atggcataga
     5101 tattagcctg gctggtctgt aagttttcat taaccaaaat ggtcttatcc agagcacaag
     5161 ccacttgtcc ttgcaaaagg tgtgtatttg gcctaaagtt aatggctaaa atagccaaat
     5221 caccttggaa ggtgtcccct tgctcggtat gagcgacaac ttttccctct atctcatgaa
     5281 tagccgtaac acgcttatta ttaataaagg tgacatggtg agtggacatt tctgccatta
     5341 caggggctat cagttctgcg tcagtctgat agaaatctgg acgttcggct gcttcaatca
     5401 gtttgacccg tttgccttgt aaggacaaac tgtaggcaag gtctaagcca atcaagccgg
     5461 caccaataac caagacctct tggctagcct caatcagttt taaactagct tggctttctt
     5521 cataatattt ggttaccaaa actttgttgg tctgtgacgt ctcaatataa tgagactggg
     5581 ggctagcacc catggcacaa acaagcgttt cataaccttc ttcaaaaact cgtccttgac
     5641 tgtctttgag aagcaaggtg tttgagggag cttcgatagc taacacttct gcttgaataa
     5701 accgatggtt agactctatt tgtgctgcta ggcaggctct tccccacata gcatcagaca
     5761 ggtcttgaat gtctcctctg aataattggt tgataccatt tggaatataa ttgggacagc
     5821 tttccttatc aatgagaatg atttgggaat ctggattgag gtccttatat ttatcaacaa
     5881 aggctagacc agcaaaggat gccccgataa catgtatggt ctttgtcgtt aatgtcataa
     5941 tagtattatt atagcagttt ttttaagata tgaaagcgtt ttacctaatc ctataaagaa
     6001 aatgcaaagg agctggccta tgatagccaa cccctttagt gatggttagg acatgacttg
     6061 gaaaagcaaa actgctaaga ccgctccaat aattggtcct acaacaggta tccaagcata
     6121 agaccaatca gaatctccct tgttgttgag tggtagaata gcatgaacta gacgaggtcc
     6181 taaatcacgt gctgggttaa tggcgtaacc tgtcgttcct cctaaggata acccaatccc
     6241 aataaccaag gtacctacac agagggttcc tagtcctgct ggcatatcat ataagccaaa
     6301 tgccaaaata ccaagcatca agacaaaggt cccaaagatt tcactcaata ggtttgagct
     6361 agtatctcga atagcaggac ctgtcgcaaa tgtccctaaa atatcagcct gactctcagc
     6421 agccagataa tgtggcctga actgaaggaa taccagagtt gaaccaacca tagctcccaa
     6481 tagttgggca aggctatagg caatggctgt tgaccaggca atggttccac tcatggcaaa
     6541 agcaaggcta acagctggat tgaggtgggc aggggcaact ttgccactga taaaggctgc
     6601 cacagcaact gcaattcccc agccagtcgc aatcacgatc cagccagaag catgggtttt
     6661 cgttttgggc aagacaaccc ctgctaccac accatttcct agtaaaacca ataaggctgt
     6721 acccaaaaat tcgccaaaga tatccatatt aaccctcctg atggcctttt aaggcactca
     6781 aatcattgtc tgcaatcacg cgacgaagat cgtcttcttg tgccactctt tcctgatcag
     6841 accattcaaa atgtttagcc atttcattaa tcactgggtc aatcaaagca tctaggctat
     6901 ctcgcataaa taagaggtga tttgttcttc tcaagaaata atctgtcggt ttaagagcca
     6961 tttcataatc catcgcataa tgtaaggaca aggtttcagc taaacttaac ccttcagctg
     7021 ctgttaattg acgagttaag gcaaagactt ttggcgcatt agaaccataa aggtttgcca
     7081 aatacctagc atcatccatc gaaagaccac taagagttcc taattgagca taggcttcta
     7141 tttccgaatc tacattggct ggattgattt cacctcctga aacaggatag gtttttgaat
     7201 tgataagctt gaaggatttg ccaaactctt ctttgaggat ttgaataatc cctgtcaatg
     7261 ctccttcagc cattttgcga tagtcggtaa tcttaccacc tgccaaggta aagagtccat
     7321 tctcatcacg ctcaaaactt gaacctcgtg acactgcaga cggatccaat tctttttcag
     7381 atgtgctggt ttcaacctgc ttaatagctt tttcaacagc ttctcggcta tcttcgtggt
     7441 taatataggc tttgacagta tcaaccaagt gatcaaaact atcatcactg actttaccgc
     7501 tgttgccacc attgtagtca gaagcactat tacctgataa caaggggcga agaccagccc
     7561 aactgctttc aatatcatca atggtcacgt tggcatttgg aaagcggtta ttgacaacgc
     7621 ctaacaaata atccacatct tcttgagtaa cttgtgggtg ctccaagtct ccagtgtagt
     7681 ccgtgtccgt tgttccaaaa taagtttttt cctcacgtgg caagacaaag accatacgac
     7741 catcatttaa ccctgtgtca acatagacag gttgagacac tggtaatttt tgacggtcca
     7801 ctaccagatg cacccctttt gtagggcgca tttgatgaat cggttgtccc ttatgagaga
     7861 attgacgaat ctcatcactc catggacctg tggtgttgat gactaattta gccttgataa
     7921 tgatttcttg atctgacagc agatcacgcg ccttcacacc aataatctta ccattgtcat
     7981 ctagcaagaa atcttctgct ttcacatgac tagcaataag agccccatca cgattagctc
     8041 gtttgatatt ttcaataaca agccttgcgt cattattgcg gaaatcaagg taaaccccac
     8101 caccaagcaa gccttcttgt tttaagtctg gttctcgttt taagacttct tctttggtta
     8161 acaccttgtt ggccgctggc gtattggaca cgcctgctaa aagatcatac aaatccatag
     8221 cgaccttcaa acggaacatg ctaaaggtac tgccaggttc gtcataaaca ggtaataaca
     8281 tagggtctgg ttttggaatg tggggtgcaa tttgttgcac cacagcccgc tctgacaccg
     8341 tatctgaaac cacctccaca tcaaattgtt tcaagtaacg aagccccccg tgaaccaatt
     8401 tggttgaacg gctagaggtt ccttgagcaa aatcttgcat ctcaatcaga cccgtatcta
     8461 ggccactagc tgccgcctga agtgccacac cagcacccgt aatacctccc ccaataatca
     8521 gtaggtctaa atctctttct tgcatttttt ggagagctaa gcgtcttgtt tctcttgaaa
     8581 attccattcc atcctcctct agttattttg catcgtcatc tgcatcttct tcttgggtga
     8641 aaacttgagt tgctttaaca gcgcgcttcc aacccttgta taatttttct ttgcgcgatt
     8701 cattcatgct agccttaaag agctggcctg tggcatttaa ttctttcaaa gcatccatat
     8761 cttcccaata ccccacagca agccctgcta agaaagctgc tcctagagct gttgtttcta
     8821 aatttttagc acgggcaata tcaattccta aaatatcagc ctgaaattgc atgagcatat
     8881 tattcatggc tgcaccgcca tccacacgga gctgttgaat gtcaatacct gaatccacct
     8941 gcatggtatc aataacatct cgcacttgat aggcgataga ttgtaaggtt gctttgacaa
     9001 agtcttcttt gctggtacca cgtgtcaagc caaagacaga tccacgcgca ttagaatccc
     9061 agtaaggagc tcctaaaccg gtaaaagcag gcacaacata aacttcatcg tcactagttg
     9121 atgctagagc gaactgttca gattctggtg aagtctcaat cattttaaga ccatctcgca
     9181 accattgaat ggcagagcct gcaataaaga tggaaccttc caaggcatag tgaaccttcc
     9241 cattaatccc gtaaccaatg gtggtcaaaa gattattact cgataactgc atctcatcac
     9301 cagtattcat gataatgaaa gaacctgtgc cataagtgtt tttcaccata ccaggctcaa
     9361 aagctagttg gccaaacaaa gctgcctgtt ggtcacccgc catacctgaa ataggcactt
     9421 cgcccccata aaaatgaaag gcagctgttt tgccataaat ttcagaattg gatttaacct
     9481 ctggaagcat atcttttgga atatttaaaa gctctaaaat ctcatcatcc catgttaagt
     9541 ctttaatatt atagagcatg gtacgagccg cattggaata atccgtcaca tgaacagcac
     9601 catctgtcaa tttccaaacc agccaagtat caatggttcc aaaaagtaac tcgccttttt
     9661 cagctcgttc ttgagcacca ggaacatggt ccaaaatcca acggatcttg gttgcagaaa
     9721 agtaagcatc aataacaagg cctgtctttt catggatcat ttttgtatgg ccatcttgtt
     9781 tgagttgctc agcaattggt gccgtctgcc gtgattgcca cacaatagca ttataaatag
     9841 gtacacccgt ttttttgtcc caaaccactg tggtctcacg ttggttggta attccgattg
     9901 cttcaatttg gcttggtttg atgctagact caataaaagc acccgcaata acagactgaa
     9961 ccgaattcca aatctgatta gcattgtgct ctacccaacc agcgtgtggg aaaatctgag
    10021 ggaattcttt ttggctactg ctaacctttt cccctttttg attgaaaata atcgctcgtg
    10081 aacttgttgt tccctgatca atagccatga tatacttttc ttgcgacatt cattaccctc
    10141 ctttaagtaa gcgttttcct atttgattct attatagcta attttatcag aaatatatta
    10201 tcaagaattt ttaaagctaa aaaaaaagct gataagatag gtagcttatc ccactagatg
    10261 aacttgaaaa atccactgat gacaaccacg tctcctcatt tctaacgagg taatctttct
    10321 tatcaaagaa aatcaaaaga cccaacaatc actctgctaa tccagagtca tcattgggtc
    10381 ataaagagaa ctaagcctca aaggcaacac ggtatcaaac agccgcgcct aagaggcaaa
    10441 gacaattgga cacaagagtt aaggctgtct tattcattac agtccttgat tagtcattga
    10501 ttggttcaga agatttttcc acaatatccc ctgagttggc gtcaatggta tagctgtatt
    10561 cttgatcttt gttttgaaac tcgatttcat acacggcttt gccatcttca ttatcttgtg
    10621 taactgatag catttgagca tcagcttccg taacagaagc atcttttaac gcaattgatt
    10681 tggctttgtc ttctgagagt ttaactttct tgctagtttg acttgtcttt ggttgattat
    10741 ccatatgatc gtctttatca tccatatcac aggctgcaag actgagtaaa gagaggctgg
    10801 ctatggctag tagagagaat tttttaattg tcataagtac taccttcttt ctttgatttc
    10861 ttctattata actcaaacac atggtttttc ccaatatttt gactatacaa tataaaaacg
    10921 tgtggtcact ttgaagtatc ataccattta aaataaaagc taacagtcat cacgataaac
    10981 aaaaagcagt tcagagctgc tttttgtctt atgattttgg gtcatctaat gaacggccgt
    11041 gcaagccttt ttcacgttgc acctgtctta atttttcagg ggtcacgtcg tttccttctt
    11101 cgtccaccaa tttgatgcct tcgatatggt gtctgacaga gcgacgatag ccttcaatgt
    11161 attcttcacg gagttttgcc tgttccactt tttcaggtcc agtcaagcct accgtttttt
    11221 tctttttagc cagctcattg atacgagcaa tttttttagg atccatgtta agccactaag
    11281 agcctgggaa aaaagtataa ggcttaaaaa actgacttga ctctcactgt gaaaagcaat
    11341 gtttaaaggc cttgtttttt ccactcgggt actgaactca cttttctagc taagtcccca
    11401 acggctcttt cctttctatt tacttggtgt ttagttggtt aaaagcaaca atggtcttag
    11461 ctttgcttac taaatctgat aaaatagcta aacggttgtt tttaagggct tgatctcctg
    11521 ccataaccat tgtgttatca aagaaatcat taatcactgg gctaagggca aagacctgtt
    11581 ctaactgctg ggcagcactg cctgctagag tcaagccttg aatagctgca aacaaagtgt
    11641 tttcttgctc attttcaaag aggctagggt ccacctgaac agaagcgtcc gctttttctg
    11701 ccaaattaaa agcacgtgac aaagattcaa ctgctggttt gtaattttcc gtatgactgg
    11761 ctttgacaag agcttcagct gcggccaaca tttctggaac cacaaaggtt gaacttgcta
    11821 gaatagcttc ccgaatgtct tttggtgcgg ctttgcccat catcttatcc acacgagcac
    11881 ggataaagtt catcacatcc gccttattgg cataggtcaa actatcaaag gacaagtcat
    11941 ataagctatc taccagctta tccattggga tgcgccatcc aaaatgatca agaatacgga
    12001 caatcccttg ggttgcacga cgtagagcat aaggatcatt agagccagat ggaatcaagc
    12061 caacagaaaa gaatgacaag agagtatcca atttagctgc caaggccagg acagcgccaa
    12121 ctttggtttc aggtagcgca cctcctgcag catcaggtaa gtagtgttca cggattgctg
    12181 ttgccacagc agcatcttca ccagctagaa gggcatattt ttcacccata atcccttgca
    12241 gctcatcaaa ttcacccacc atacctgtta acaggtcaaa tttgtaaatt tgggcagcac
    12301 ggtcaacagc tgtgacttcc tcagcagata ggttggcttc cttagcaagt gatgcggcaa
    12361 tgacacgcgt acgatccatg tgttcagcaa gagagccgat tttttcatgg aaggtcacat
    12421 tggtcaattt ggcaaccaaa tcagcaattt gcaatttctg atcctcacgc cagaagaatt
    12481 caccatcttc taagcgagct accaaaactt tttcgttccc tttaataaca ttttcaatgg
    12541 cttgatcatt cccattacga actgatacaa agtttggcat caagtgacca gcctgatcac
    12601 gtactacaaa ataacgttgg tggtttttca ttgatgttac caatacttct tctgggacat
    12661 caaggtattt agcctcaaaa cttcccatga aagctgttgg aaactcgacc aagttcaaaa
    12721 cttcattaag caagtcttcg tcaatgtcaa cttgcacacc ctgctccact tcaagcgtct
    12781 tgatttgctc cacaatcatc tcttgacgct ctttagcatc agcgataaca aactggctgc
    12841 gtaaatcagc ctcataagaa tcagcacttg tgatagtggt ttcagtacct aaaaaacggt
    12901 gaccacggct gacgcgtcca gaatgaatat ccaagaagtc aagttccaag gcctcatcat
    12961 tcaacagaac tgtcaaggtg tgaacaggac gaatgtattc aaaactattg ttagcccagt
    13021 gcatgctgac tgggaaggtc attgctgata acacttcagt aacgcctaga agcacttcct
    13081 tagcaggttt tccagcttcg tgtttggtca cataaacgta ttcttctcct ttgacttcgc
    13141 ggaattcgat agcatctgtg gtcaagcctt tgccacgaac aaatccttga gcagcttttg
    13201 agaaattccc atcagcatca agggcaattt tcttagcagg ccctttaaag tcctcagtca
    13261 aatccgtttg ctgatcagct aatccagaca cacgcactgc caaacggcgt ggagttgaaa
    13321 aggtttgtat atcttcaaaa gagagacgat tttctgttaa gaaagtcgcc aagcgctctc
    13381 ccagttgttt ttcacttggt gtgaccacgt aggctggaag ttcttccaga ccaagttcga
    13441 ttagtagatt tttactcata attaagatac caagggcgtt aagcggacac catcaaaata
    13501 gcaaagcgac gcaggtgctt gcacctagga agtcttggtc tttttgacat agtccgtagc
    13561 ccgtgttcag ttcctttctc taaaaagtat ctttttgatt gttcccttag gtagggggga
    13621 cgcaaagtga aattatccag tggataattt cagaaaacaa aagtgttcca ttcctagtta
    13681 gccagcctaa agtctagcca actccctcgt tcgataagta accttaccga attgtcacta
    13741 cagcgggagt aaccttgact cggcgacctt cggtcgccca cttcttgctc gctcttaaga
    13801 ttacaaagct cgcaactaga tcatctttaa atcgacttat tcgtcatctt cagctagcaa
    13861 gattgcgcgt gttgcttcat ccaacagtgg aaatccaagc ttcttgcgtt ctgcaacaaa
    13921 ggtcttagca acgacacgtg ccaaattacg gatacgagca atgtagcctg cacgttctgt
    13981 gacggaaaca gcgccacggg catccagcag gttaaacgta tgagaacatt tgagcacgta
    14041 atcataagct gggtgaacca aaccttcttc tagggcacgc gaggcttctt tttcaaactt
    14101 ttcaaagttt tcaagcagca tgtcttggtc tgatatttcg aaggaatatt ttgaatgctc
    14161 atactcaggt tgtaagaaga tttcaccata tttaacacct ggtgcccact caatatcata
    14221 gaccgaatcc acttcttgaa tataggaagc taagcgctca agaccataag ttacttctgc
    14281 tgtcactgga gatgtcgcaa ggccaccaac ttgttggaaa tacgtaaatt gtgtgatttc
    14341 cattccatca agccaaactt cccaaccaag ccctgctgat cctgttgatg ggttttccca
    14401 gttatcttca acaaaacgaa tatcatgttc taaaggattg atgcccaatt tttccaaaga
    14461 agcaaggtaa agttcttgaa tatttgatgg tgatggtttc atgaccactt gaaattggtg
    14521 gtgttggtaa agacgatttg ggttttctcc gtaacggcca tctgcaggac gacgtgatgg
    14581 ctctacataa gccgcattcc atggctcagg acctatagca cgtaagaacg tgtaaggact
    14641 catggtccca gctccttttt cattgtcata ggcttgcatg agcatacaac cctgatcatt
    14701 ccaatattgt tgtaaggtca agatgatttc ttgaaaggta agttttttag acatttcgta
    14761 ctcctttgat agtagtaaaa tggtatatca ttgacaatcg tttttttgtc atcagtaaaa
    14821 tacctgacga tgttactagc atgtattaca ggtctaggca ccaaaaaacc gcattttgat
    14881 gctcctaaat cataagacct aggggcgtca aaacgcggtt ccaccctaat ttattacttc
    14941 atttatatag tatctttttg ggcaatattg acaaatatac ttaatcacac tgcccaaacg
    15001 gaagcgccaa tctgcagtcc taccattcgg ctctaactac cccgaactcg ctttagataa
    15061 gatacttgca tcctttttcc tagagtctag tttagcataa agccattagt ttgtccatca
    15121 tgagcttaag gttttgttcg agtaccgttt ggaataatca cttccgctaa tagcttgttt
    15181 tcttctcgaa tacgtaaata tattactaca atgtagcatg ggaaaagaag catagccgta
    15241 attttagcat ggcaaagtaa ggctatgccc accagctcag gggcgatatt taaaaagtag
    15301 ttaggatgtt taatcgtttt gaacaaccag tgatccacat atttgtggtc ttttgctaac
    15361 atcaatttta cagtccaaat gtcacctaag atacgtgtca cttcatataa aacagctact
    15421 gataataaca tcaacaaaag acctaaaaaa ctaatgccat caaacttaat ttgtttaagc
    15481 agcgcttcaa tcaccgcaaa cacataaatc ataatgtgaa gtaacgtcaa aaatttcgtg
    15541 ttctgagcac caaattcctg tcctccttgg gctaatatgg ctttttcatt tgttatcgat
    15601 ttcttcaaaa atactaaacg aatagtaaac atagctaaca tcactaaaaa gatggtcaca
    15661 atacggctcc ttattttcaa taatagtttc tttcacaaaa cactaataaa gattatagct
    15721 aaatgataaa cctttgtcaa accgttttca aaaaagattt agcgaattat ggctaaatct
    15781 ttgtagttcc ttaaaaactt gtagtatcag gggtaggaat cgctgacatt cctgagagat
    15841 agcgaattgt ttttttatct tcttgtgtca agctcacatc aaaaatagcc atattttcct
    15901 tgatgcgctc atcatgcacc gattttggca agggaataaa accttctgcc agcgaccaag
    15961 ctaaggcaac ttgtgccact gttttgtcat atttattagc taactgctgc atagtctcat
    16021 tatcaaaaat ctccccttgt cctagaggac tccaagcttc caataaaatc tcatttgcct
    16081 tacaataatc aaccacttcc ttttgatagc aacctggggc taatcgaatc tgattaattg
    16141 ctggagttat tttagctgtc tcttgaagag cttctagatg atgcaccata aaattgctga
    16201 cgccaatgct tttaataagc cctgcttcaa ccgcctcttc catatattgc catgcttggg
    16261 catttgcctc tttccaagtg ttacgcagag cttttgggtt tggccaatgg ataagataga
    16321 gatccacata atccagacca agacggtcaa gagaagcagc taaagcgtct tttgcccctt
    16381 cataactatg ggcgtcattc cagagtttag ttgtaataaa taagtcttct cgtagaaccc
    16441 cagaatcctt gatggcacga cccacacttt cttcattttt ataaatagct gcagtatcaa
    16501 tatgacgata gccagccttg atggctgcta aggtagattg gtaagcttcc tcaccatcgg
    16561 ctgcttggta agttccaaat cctaaaacgg gaatctcata gccacttgtc atttttactg
    16621 ttgttaccat cacaaaaacc tccttttatc aatatctgta agcgattact ttaatctatt
    16681 ctatcataaa gaaagaaaat acaaaaagaa ttggcctgcc agacatagct accccaatcc
    16741 ttttgtatct cttaggcatc aaaagctttt tgcccattta aataggttgc aacaagtgtt
    16801 aaatccttat caagaacaat aaagtcagcc gcatgcccag ctttgatttg accacatacg
    16861 tcgtcaatac cgacagaaac agctggcaca taagttgcca tatgaatggc ttctgccgga
    16921 gttgcgattc cccaggccac tacatttcta aggccatctt ttaatttcaa aatagatcct
    16981 gccaagtttc cactctcttt aagacgagca gtgccatttg ccacaaccac agagaattcc
    17041 cccaagaggt aatcaccatc tggtgaacca cctgctcgca tacagtccgt aatcatggct
    17101 acatgatcat gccctttttg ctgcatcaaa atatcacaag caattggtga gacatggtgg
    17161 ccatcacaaa tcaactctgc gtaagtattt ggaagattat aaaccgctcc caccattcct
    17221 ggttcacggt gggtcaatcc tcgcatgcca ttataagcat gaacccaaac actagcacca
    17281 gcttgaacag cttctttagc ctcttgataa gtaccgtttg aatgccctaa ggccactgtt
    17341 acgccttgtt ttgtcactgc agacacaaat tctttgacac catcacgttc aggagcaagg
    17401 gcaatttttt tgatgagccc tttagcagct ttttgccaag catcaaattc ctccaagcgt
    17461 ggggttttca tataacttgg gttttgagca cccttatatt cttcggtaaa ataaggacct
    17521 tcaaagtaga taccttgtat tttagcacct tttacctgat cagcaactga agcaatagtc
    17581 cctgatactt tttctaactg ctcaaaggta gaagttaagg tcgtcggtaa aaaagacgtt
    17641 actcctgttg ctaatagtcc ttcactcatt tgatgaatcc cttgggcaga attatccatg
    17701 acatcagctc ccgcatagcc atggatatgc gtatccacaa gacctggtgc aatttgataa
    17761 ccggtgtagt caatgatttg cgcatctgcc ggaacaattt ctgtccactc cccaaaaaca
    17821 ccatcatgaa gacttaggta gccagccggt ctcacctctg ttgggtaata aaaacaatct
    17881 gctttaagat agcatgtcat cttttttcct cccttttttc cttattatac gccttattct
    17941 ttactttgta aatggtatat accacttttg ggattcaaaa aagaaaacgt ggatgatcat
    18001 tcacgttttc tcttttttta aagctggtgt gaaagtactt tctctgctaa attcaaggca
    18061 tgatctgtga tgcgggtata gtgggaaata atatcaataa aattaatacc tgcttgtgcc
    18121 gtacattctc cacaattcaa gcgcttaatg tgggttttac gtaatcgtcg ctctttttct
    18181 tcaatttctt tatggcgagt cacaatagtt tgcgccaagt ctgtatcact atcaacgata
    18241 gctctaatgg catccagtgt taaacaatgc gtcaattgat acatctctgt caattcttga
    18301 cgagcagata ttgaaaaacc aatttgttta gatatgatgc cttcaattag aatgcctaaa
    18361 gactcagaat gatctccaat tctttccaaa tcacgtgaag agtcaagaat accagccaag
    18421 acttcatttt cacttgggct gagggcttcg ttagaaatat caaccaaata agtggttaac
    18481 tcctcatcga tggtatcaac tgctctttca taacgcttga ccttttcccc aaatttaccg
    18541 tcagctgtca taatataact gtaagaagct tcaaaagctt gaatcgcata agaggctaaa
    18601 tgaaccaatt ccttgtgggc atttcctagt gcgatagaag gggcttgggt aataagtaag
    18661 cgatctaaat aaagggcttc gtatttgacc acttcatctt ctcctggaat gagtctagtc
    18721 acaatcatag ctagtagact aatgaaagga attaataaga tggtattagt gatattaaaa
    18781 gaaccgtgag aaaaagcgat agtcatctca ggcgttaaac tcaactttga ttgtagccat
    18841 aacatcaatg atgtgaatgg gactaggata atcataaaaa taattgtacc gatcaaatta
    18901 aataacacat gagctgctgc cacacgttta gcagcaatat ttgaacctat agctgctaag
    18961 acagctgtaa tgcaggttcc tatatttgag cctaacaaaa taggaatagc cccctgtaag
    19021 gtcaaaagac cgcctgaaaa cagtccctgt aaaatcccga taatggctgc cgatgactga
    19081 atcaacatgg tcaaagccgt tccgataaag acaccttgga agggtttatc acctaatgtc
    19141 gctaaataat tttgaaaggc tgacacagat ttcaaaggat ccatggcatc tcccattagg
    19201 ttcagcgaga agaaaattcc tccgacacca aaaatgatac gcccaaaatt gttgagcttt
    19261 ttattagagg taaagaaaag acaggctgca ccaataaaaa tcatgggcaa ggcgtaatct
    19321 cctagtttaa aaccaattaa aaacgaagtg atagtcgttc caatattagc ccccataaca
    19381 attccaatgg cttgtcgcaa atttagcaaa cccgcagaaa ccaaaccaac cgtaattaca
    19441 gttacgcctg aactggactg aattaaggca gacatggcaa ttccgactaa gataccaaaa
    19501 aagggattac tggtgtattt atcaatgtaa taccttagtt tatctcctgc tgcttgttgc
    19561 agaccatctc ccatatactt gatactgaaa agaaagagac ctaagcctcc aaagaaatga
    19621 aatgcaatgt cttgccaatt tactgacaca atattgtcct cgctcaattt tttagtctat
    19681 tctattttaa tgtattacgg tctttatcac aaggtttttt taagcgtttc tgtgtatacc
    19741 gatgtcaaca tttgcatatt attggtttga taaggtgtta ggcttttccg atattttaca
    19801 tcatttgttt ttgcacaaat cttttcattt cgtttaatta gaggtataat atggctacga
    19861 tgaaacaata tcataaagga gattccatga ctaaatcaca aaaagaggcg ctttattgga
    19921 tgttgagtgt tctaactatc actctaatag gtggctcctg ccttattttt ggatcccacc
    19981 ctcaaacgca agataaggta gctaaacatt ctaaaagtgc tgctagttta ctaaaaaaag
    20041 cagttaaagc agttaatgac gctgatcgtt tagccactgc agctgctatc caagaagccc
    20101 agaaagctgt tgataaatta gcagaatctt ctaagaaaaa aacgctacaa gaacagctaa
    20161 acgttgccaa agcaaagcaa gagcaagaag atgcagctac tcaagcagtt aaagctgctg
    20221 aggagactct caatcaaaat cttaaagata tcgcccaaaa agcagttaac gacttaagta
    20281 acaaaggtaa aaaagccgct ttacaatctc ggttagacgc tattttacca gcgaaaccca
    20341 ttattgatga atttccaaga caaagtggag aaataacaga taactcttac tggacacctt
    20401 tcccaggaga cgtctcagat acttatgata attcccagtc acctacttta gacccaagct
    20461 cagaatcttc agcttcagat gttacaccac aacctagtca tcctgatcca attccacctc
    20521 agacctcttc agaaccttcc gactcaggag acaagcaatc atcaaaagag taatacaaca
    20581 gtttttcgta aaatcaatca ataaacgttt tagacggcta tcttagtgat tagtcttcct
    20641 gacatcttaa aaaagctagc tcaaatcaaa agagtctagc tttttgtttt gttagatagc
    20701 attaaatttc gtagcccatt aaaagtcctc cgtcttcagc ataaaagcta cacaaacctg
    20761 aggtccttcc agtttgaatc acagcatcag gatataaaga tttgattttt tcactgatct
    20821 gctcacaaat ttttggattt tgagcatgag caatgtaaac ttttccgcct acataaccct
    20881 ctttttgaat ttcttctatc aaggcagaaa ctgctttttt ttgaccacgc gctttttgaa
    20941 gaagttcaag cgttccttta ttgctagctt tcccaaccat tctaatattg agtaagccaa
    21001 ttactttacc tactaattta ctcagtcgac catttttaac caaattatca accttggcaa
    21061 gcacaaaaat caaacgtgtt ttttgctgat aagctgtgat ctgtttgaca acttcttcaa
    21121 aggataatcc aagtttgatc aaccgctcaa gctccagtac gagcaaatcc atctcgccac
    21181 ctgctgataa agaatcgatt agatgaatat tgacattagg attttcttca agaagttcat
    21241 ttttagccag tcgtgcacta ttatgactgc cagataaggt ccctgtaatt gtcatcacga
    21301 taacattatc tgcacctcta taggcctgca aaaaggcttc tgggcttgga cagctagatg
    21361 tcgttgcttt agacgactgg tacatagttg tcatcatatt atcgatatct aatccatcat
    21421 catctctaaa aatttctgtg ccaatctgta gggtcaaagg cacacgttca aagcgcaact
    21481 ctttggattg tctagtcaaa cttctaagat cacatcctga atctgttaca attttccaag
    21541 tcatttttta tccttctttt tctctaattt gtgttcggta acaaagacca gattattaag
    21601 ccttcgctaa gatgtctagg ctaatggtaa taactagtca ttaaatccta tgttttatta
    21661 ctagcctttt caatagttag taaagtcatc caatagagct atacaaggag gtaatgaggc
    21721 tcctgataac taactttagt tgacaaatta agacttttcc cataaaatta tatcattatt
    21781 aagtcggttt ttgctactga taactcatca gatgtaacac ttgaaaggta tttgtgatga
    21841 ctgataaagc actctcaaaa agatcacttc aaaacttaac acaatttaat aaagaaacac
    21901 gacgcatagc acgtgaatct atggaaatcg ccttactaaa tcttctagaa acaaaacctt
    21961 taggtgatat tacgatttca gaattggtga cgaaagcagg agtatctcgt aacgcttttt
    22021 atcgtaatta tacctctaaa gaagccatta tagaacaact gttagtaggg gttatccgtc
    22081 gtatttttcg tggactaaaa caatttgata ttaaaactca ggcttatcaa gcttggctct
    22141 atctttttac tgaagctaaa aaagaagctc agcttcttaa aatgattttc aaacatcacc
    22201 tgcaccatct tctaacacga ttagtcacta aacgtctgaa agcttatcaa aaattaaaag
    22261 acaaaaaaca atcgcactat aagcgccttt tttggagcaa tgctattgtt tctgtcttga
    22321 caaactggat ttcagatgac atgatcgttc ctgccgaaga aatggctgct atgggcttgc
    22381 ctctattaac gtaaaaaggt tccttttggg aaccttttta cgttaattgt tagtcttttt
    22441 gagctacaag tgcaaactga cggatagcct gggccacacc cgccatatca ttagtcaaag
    22501 tgactttgtc agctaatggc ttgatagctg ctgaagcatt ttccatagca actcctaaac
    22561 cagcataagt taacatctca atgtcattgg gagcatcccc aatagccatc acttggtcag
    22621 cagttaaacc caaatcttct actaattctt tgagagccga tgccttgctg actccctgag
    22681 ggagaatttc taaaatatta tcttggctac gaacaacatg aaaactctga ctaagctgat
    22741 ttctcaccgc acgttcaaag gcatctagcg cagctttttc tcctaagtac atggcttgaa
    22801 aaatcaggcg aggagtgtcc gacagctctg ctaaggagac aggcttgaca atggtaaata
    22861 ccaaatctcc atcttcctgc acaaggtctg gcacttcttc ttcaagcacc aaataatcgt
    22921 tttcctcagt taaagtcagg taaatatctg gaaaactttg gcttagctct tccagcaatt
    22981 caatatctga aaccttcaac atttttgaat ggcgtaattg ccagtcagga ctactataag
    23041 tactacagcc attattgata atgaggaatt cctcttgtgt caaacctaat tggtcaaaat
    23101 agggtcttgt ccctgactga ggccggcctg tgcataagac aatttttaag cctgactgag
    23161 ctgcttcttg gatggctgtg atattctctt ttggaatctg tttgtcctgg tttaataagg
    23221 tgccgtccaa atcaattgca attagttgaa tcatcctatc tttcctcttt ccatttgatt
    23281 ttagggaggt tccatttttt acggttgcca atcatgcgta aagtcgtgag taaaacaacc
    23341 aaggcataac attcaatcgt tgaatctgct agtttaaaat gcaaaacaat agctgcaaga
    23401 atagaccacc cagcatagat ttcactacgc aaaacactag gttttcgccc tgccagaata
    23461 tctctgacaa caccaccgcc tgcaccagtc aacacagctg ctacaatgac agcacttaaa
    23521 ggctggttaa gacggacagc atgcaaggct ccttggacac taaaagctgc cagaccaatg
    23581 gcatcagtca aaacagctgc ccgtacccaa cctctagcca ttagcttagg aaaaagcata
    23641 atcaaaacca tagcaaagaa agcgcaagtg aattctggct tttgccccca taaggcctct
    23701 ataggtaaac caattagggt gtttcgaatg gctccgcctc caaaggctgt cacgaaacct
    23761 aaaataaaaa tccctaaaat atcaaattct tcttccatgg caacaatagc accagaaaga
    23821 gcaaaggcaa tggtcccgat gatatttaaa atttcccaca tatcaattgt cataagctac
    23881 cctattgtct tttagtcttc ttttagttta ccacgttttc ctttaaaaaa taagtagaaa
    23941 aagataaaat gtaaggataa aaaagcaagg ataaaaccca ttttcatcct tgctacaaaa
    24001 gattcaaaca attatcccca tacttatctt atcacatcaa tgagagctgc ttgataggat
    24061 aaggttgttt tagatttttt ccgtccaagg gctagcggtc tcttcgagta ccctgtttaa
    24121 ctcgtcaata ttttggaagc cttcagtgca tagccacttt cttgcttcgt cctctccttt
    24181 agtaatataa actggaacgg atcctgccca cgtggcacgc ccacacaaaa caccactaaa
    24241 ttgagcacct gctgctgctg caaagtataa tgtctcttga aaaagtttgg cagatacgcc
    24301 tgcactcaaa tagatataag ggaggtggct ggcagcttct tggtcttgaa aagctttaat
    24361 agcctcagct tgactgtaat ggacttcccc ttcagtaaaa ccttctacat aagccatatt
    24421 aacaggaacc tctactttta gcacatcaac gccaaaacgc ttatccgaaa atactgacat
    24481 agcaccgtta accttatgtg gcttaagctt tgcgtatgcc gcactgttgt tatctgatat
    24541 tctctcatca taactcaaaa gttcaagaaa aaaagggatg tcttcagctg tacattctga
    24601 accaatgcgt tcaatataag cttgtttttg taaattgatt tgttcatctc catcaacatc
    24661 ataatagagc aaaaatttaa tagcatctgc acctgctgct ttcaaccgtt tgaccgacca
    24721 ttccactaag caatcgggta aacggctagt ggttgtagca tcataacctg ttttttcgta
    24781 agctaacagt aagcctgtct gattagctct taccttagta gccagcaacc catattctgg
    24841 atctaataaa atagatgaag cataaggcgt caattcctca gaaacgagaa ctttcaatgt
    24901 ttctatctgt gtaactgtcg cttctccttc ttgatgtgct gccatcattt gcttcagtgc
    24961 acctcgttga tcaaaagcta aagctgatat gattccttga tggctcactt tttctaagta
    25021 atgtctttta tttgctgtga ttgtcatgtg atacctctct tacttgaagt tgctgatata
    25081 attgtttaaa agttgccata gtcatcaaat cttgataata gtgagtagct agtctcctag
    25141 gcagactgcc tgagaagtta agacatcaaa cggcttagca atagtactca tgtggctcaa
    25201 agagacttcg gcttcgtcca catcactgta gggaccagct tccaaaattt ttgtctgcat
    25261 gccttcatgt aaaacagcaa tacaatttct cgtttcccct ttgattttga aaaattggtt
    25321 agaaatgccc tgttcttgta actgatgaat gataaagtca cccagcttac caccactaaa
    25381 tcctgttgcc ataactgacc agcttttgct aacattctgg tcacatttag ctccttatca
    25441 ccagctgttt ttgccgttct gtcaacacaa ttaaccgtgt ccatagccag acaatctaaa
    25501 ggataggaaa tagcgacaga aggatttaag ataactgtta aactcatctc ttcttcctaa
    25561 tcgtgatact caccacgatc ccatttttcc aaaaattctg taaaaaaatc aggatcttct
    25621 tggttggcat gatgactttc caagtgggct attttagcaa ttagcttctt attctcttca
    25681 gtttctttgt attctgcctt gataaaagca tctataatat cacacataag aagttcaccc
    25741 gtgattttac caccaaagcc aatcacattg gcattcaatt cttccttggc ataaagcgct
    25801 gttgtcatat ctcgaacaag ggctgaacga atacctggta ccttgttcac ggcattatta
    25861 atgccaactc cagttccaca aatacaaaca cccaagtctg cttgaccatt aaccacagct
    25921 tcgccgactt tttttccaaa aatagggtaa tgggttcttg tatggtcata agtgccacag
    25981 tcaataacgt catagccttt agatttcaaa aaatcagaaa cagccatttt ttcgttggtg
    26041 acaatatggt cacaaccaat cgcaattttc atcactttat cctcctttag gccattttat
    26101 tgagcatgtc aacacgaatt tgatgacgac caccatcgta gggaccagtc acaaaacctt
    26161 tgacgatatt cttcgctaat tctggaccta caatctctgc ccctattgtg atcatgcggg
    26221 cattgttgtg accgcgcgtc atgtaagcag agcgttcatc tgacacttca gcagcaacca
    26281 ttccttttaa ttttgtggct accataaagg gacctgctcc gtaagcatcc accataatgc
    26341 ctaaacgacc ttctgcttca ttaacggctt tcgccaccgc taatgtgtta tcaataaaat
    26401 cactgttaat atcagtcacg tcaataatgt catagccttc ttcttgaaga aaacttttga
    26461 tcaattcttt taatgcattt ccgtgtgcat ctgcacctaa aataatagcc atagcttttc
    26521 cttttctaac ccaaaacgct tgccaatcta gagaaggggg acatgattac ctgtccttag
    26581 atcaagatga ttgccagtag tcttagtgtc ttccattatt tctttcaaga caaagcactt
    26641 gtgggttccc acagagcgcc ttgccttaca tgagaaatac tcttttcacg ttagggagta
    26701 aggtagaaat accttactcc ctaatttttt agtcagtcac ctgacctgat tttatttcat
    26761 tgttttcgca tactcagcgt tacgtgcctt catttggtta gcataccaag caaagagacc
    26821 taggtaaatg gccacaaaga tgattagcgt gatgattgag gcaatctgac ctgttgtcgc
    26881 ttgaccaatc acataaccaa aaattttttc cattggtcct tcaagtgttg aatgcgtaat
    26941 caaggaacca gcgcttgtac ctgctggaaa agcccctact tttttagcca actctgtcgc
    27001 aaatggagca atcatagttc ctgacaagag gaataatggc aataagaggg aaccaaaaat
    27061 aatcatgcga atcaaacgac cacgtgtgac cacaagaaga gctggtgtca tccccatagc
    27121 aataattcct gccagtggta aaatcccatt gccaactttt gataggagaa cggcttcaat
    27181 caacatgatt ggggcaagaa tattggcaca ggcccagatt tcagcacgac cagcaatgaa
    27241 gggccagtcc aaaccgatat tgaaacgacg cccatgcatt ctagcattgg caaaattggt
    27301 aatcccttgt gacaaaggct caacagctgc gataaaccaa gagccaatca aagagaaaag
    27361 ttccaagcag gcacccgcgg taaagcctag gccaaaccaa tttttgatag attcaacagt
    27421 gaaatgagga tctcccataa tcccaatcac aaaacctaga gccattccga taaagaactt
    27481 agagccccag aagccaattt ttttgttcaa tttagcagca tcaaagtcat atttatccag
    27541 ccccggaaag accttgtcaa aaatcttatc taagaccata atgattggat tcatcatgta
    27601 gttcatgtga gttgaagtca ttggtgattg aggccctgtc ccaagaaggt catcaaaggt
    27661 cggtttcatc aaatcagagt taatgatttt cagtacccca acaagaataa ctgccacagt
    27721 agcaatcaaa agagacacaa agactggtaa atggttacga gccgcatacc acataatcaa
    27781 tagacccgta atggacaaat gccaaatatc aaaaatatcg acgtcaaggg tgtccgtttt
    27841 tttcatgaca atcatgacaa tattaaccac cagcatcacc agcaagaaat aaagggtgta
    27901 aggggaaccc caggtaattg ttgcaagcgg tgcccaaccg acatcaataa tgtttaaact
    27961 gatccctgta tttttaacaa aggcctgtaa agactctgaa aaagcccccg tcaaaattcc
    28021 aataatggct ccaatccctg tcaaagcgat ggctaactta atcccacctt ccagtgcctt
    28081 tgtgaattta accccgaaaa tcatggctaa acctgtcatg acaatcagca tgaccacacc
    28141 tgatcccaac tgaataggaa atcccagaat cttgttaata atgtctaaaa aaggttgcat
    28201 catcttgtct ccttatgttt ttattaactc actgcaaatg attttcttta atcacgcgct
    28261 ctaattcagc aaaaacaggc tcactcatga ttgggatacg atagagaatc ggtcctgctt
    28321 ctactatggg aatcggcatc tcaaatccca agtcagtttt tgcaatcggc gtaaaaatat
    28381 cataacgaga caccaattct tctgtgatgt ctttgaccat caccgcatca cagtgaacat
    28441 cgtaaccacg gtcactcatc tgagtttcaa tcgcatcttt aatttgatgg cttgagttaa
    28501 cccctgcacc gcaggctgct agaattttaa tcatgctgaa acactccttt ttctattaaa
    28561 tagtttgaaa tagcttgttt atcatctttt agactggcta gatagctaag attgcctttc
    28621 gtaataaaga aggtaatgag attggataga atcgtcgttt gaccctcgtt ttgactattg
    28681 ataataaaga agaaatccgt taccaaacag tcttcctctg gattaatcat gtgcttaaag
    28741 gtaagggctt gactatttct aacatagacc acttgatcaa ccaagcaata cttggtttct
    28801 gtatgcggaa tagccgcata caaaatatct gacccatctt tgaggtccac tttgagtcct
    28861 gtcggaaata ccgcctcacg ctccactaaa gcctgatggt actcttgcgt cacataccca
    28921 accttttcca agtggctagc aacaagatca aaaagctctg gctgcgtcct tgcttcagta
    28981 aatagaatat taggaaacac tccctaccgc ctttctataa gtatcaattt ttaacaactg
    29041 tcatctcatc atcaacaaat tggtaaccgt ttacaaaatc attatagtat aaccttcaac
    29101 ataattcaac atttttacgc aatatttttt gttctatatg tttgtttttg ttttgtttat
    29161 tttgttttat tgaaatatga aggtctatat gctatgataa acataagtaa ataaactata
    29221 gaaaggagcc ccttagatgt taaaaagaga aagacttcta aaaattaccg aaatagtcaa
    29281 tgagcaaggt attgttactg tgaatgatat tattcagact ttaaacgttt ctgatatgac
    29341 agttcgtaga gacttagatg aactggaaaa agccggcaaa ttgatccgca tccatggagg
    29401 tgcacaaagc attaccatgc ctaataaaaa agagcggtca aatattgaaa aacaaaccgt
    29461 tcaaacaaag gaaaaatggg aactagcttc atatgcgaca caactagtca atgatggtga
    29521 aacaatcttt attggtccag gaacaacttt agaatgtttc gctgagcagt taaaaaatcg
    29581 tcagattcgc attgtgacca atagcctccc tgtctttaac atccttcagg acagcgaaac
    29641 cattgacctg attcttatcg gtggtgaata ccgatctatt acaggagctt ttgtagggtc
    29701 ccttgccagt caaaatatct catccttaaa atttgccaag gcttttatta gctgtaatgg
    29761 tatttataaa aacgatattg caacttatag cgaaactgaa ggagagattc aaaagctagc
    29821 ttttaataat tctattgaaa aatacctctt ggtagataac caaaaattca atgcctacga
    29881 cttcttcatt ttttaccatt taaacaacat tgatgctgtt gttacagatt cgcaaataac
    29941 tgaggacgtt atcgaacgtt atagtcagtt cacgcaatta ttagtagccc acgaaaacaa
    30001 ggagtaaccg tttcatcaag aatgggcagc ctgtcagtgc atcgtcctta aacaccttct
    30061 ggcaaaagtg atttgccccc agagaggtgt ttttgttttg ctcggaacac acctgctaac
    30121 gtcagagtct ttatgagtga ccacaaaaaa agaagcccag attaaaaaac tggaacctct
    30181 tttgagatga agtaaggcta ccaaaataac ctaagaccat ttatataatt caaatttggt
    30241 atccttcaaa gcacgcttga ttaggaacgt taaaggacgt cctgtcacct tagcctctcc
    30301 tttttccaaa tttacctgga ccgattgcac accggggaca gctgataatt tttcagtgac
    30361 cgttcttgcg caaccgtcac atgtcattcc tgtaacctga taatgttttt ccattttgta
    30421 ttctccttta aatggttttt ccttttaatc gcagggcatt caaaacaact gatactgaac
    30481 taaaactcat ggcaaaacct gctaacatcg ggttcaatag tggacctcca aaaagatgaa
    30541 gtaagcccat ggccactgga atcatgagga cattgtaaat gaatgcccaa aataaatttt
    30601 ccttgacaat tctcatagtc actcgactca atgacatagc tttcaccaaa tccagcatat
    30661 caggtttcat cagaatcaca tccgccgatt caatggcaat atctgtccct gaccccatag
    30721 ctatcccaat gtctgctaca gccaatgccg gagcatcatt aataccatca cctaccattg
    30781 caacttttct cccttgagag cggaggtctg ctatcacgcc tgctttttga tcaggtaaga
    30841 cttgactgat cacatctgta atccccactt gagaggcaat agccttagcg gtagcatcgt
    30901 ggtcacctgt tagcatgatg gtgtgaattc ccagttgatg caaagcttcg acggtagctt
    30961 gactatcttc tttgacagcg tcagcaatac tgaaaagagc tcgtagctgc ccctctttag
    31021 cataatatac aagggtttgg cctttctcag aagccttagc acaaaccgac tgaacacaag
    31081 ataaatcgat accaagaatt cccattaaag cagcatttcc aatcgccaaa cgacgccctt
    31141 caagctgacc agtaactcct aggccggtta aagactcaaa ctcttccact ggtagactat
    31201 cgtaaccagc ttcctgagca gcacgaacaa tagcctcccc taaggggtgt tgagaatagg
    31261 cctccaagga agcagcttct tgcaagataa ggtgatcatc tcccgaaaaa gttaggagct
    31321 tttgaagact tggtttcccc tccgtaatcg tccccgtttt atcaaaaaca accgtatcta
    31381 cctgatgtgc ttgttctaag atgtcaccac ctttaaaaag aataccattt tcagctgcac
    31441 gccctgttcc aaccataatc gctgtcggcg ttgctaaacc aagcgcacaa gggcaagcaa
    31501 tgactagaac agcgatggct gttgtcaaac taaaacgaag actttcctgc atgaatacca
    31561 accaaaacac ccctgttaac agagctaata ccaaaaccac cggaacaaag acacctgaga
    31621 ctctatcagc aatagctgca ataggtgctt tattttcttg agcattctca actagttgga
    31681 taatttgtgc taacaaggta tcatttccaa gcttatctgg tttaatcgtg agggcgcctg
    31741 gcccattcaa gctgcccgca aagacattat ctttttctcc cttttcaaca ggcaaacttt
    31801 ccccggttaa aaaggattca tccaaactgc tatgtccttc cacgataata ccgtcaatag
    31861 aaactttttc acctggttga accaggacaa ggtcatcata gctaacttct tctaatggta
    31921 acaattgcca ttggctgttt ctccataccc tcacaacagt agccttcaag gataggagct
    31981 tttgaatagc ttgagaagta cggcccttag aacgactttc aaaatacttt cctagaccga
    32041 tgagtgtcaa aatcactacc accgattcaa aataaaggga gtgcacaaag tgcgcccggc
    32101 ccagactgat ttcaaccact ccataaagac tataagcaaa agcaaagctg gttgctaaag
    32161 ctaccaagga gtccatatta ggatgtccct taaacaaagc tttaaaccca ttatggtaat
    32221 aatgacgatt taatactaag actggaatcg tcaagagtag ctgactaaag ctgtaaacga
    32281 aaggatagcg atctggttgc agaaatggag gaagccataa gcccaccatg tgacccatag
    32341 ctaggtataa tataggaatg gtgaataggg cagaccacaa gacctgagac caaataacct
    32401 ttaggtcttc gtcacgacga cctgtttgca tgtgttttgc atgttcatca aagacttgtg
    32461 caccataacc agcagctttc accgcttgaa taactttggc cgtttctaaa tcgtcatctt
    32521 gataagtaac cgtgagcttc tcagtcgcta aattcacaac agcctgttct acttcaggca
    32581 attgattgac cgttttttca attgttagag cacaagaggc acaactcatt ccctccacta
    32641 aaaatatctc tttagccatt aatacgtctc ctttctctga cagtggcact gcccaggcag
    32701 acaattacac ggcacctcaa gaactgcatt ttcttttttg acttctagta gctcttggaa
    32761 tgccccgatt tcctctaagg tcatcggtaa gtgataaagc cgttcaagaa gtagacgcgt
    32821 gtgttgccgc tgacaaatac cgtctaaaac agtcgctagt gcttcttttt gtagcaaagt
    32881 ctcatccaaa agagcttgat aaatataagc tcttccttgc cgataagacg ttaaaaaatt
    32941 ttttttaact agcctaccaa tgagggtctt aatagtggaa tctgaccatt gatatttttt
    33001 ccttaaaata gtaataatat cgctactttt aatatcacca ctggcccaca ccacacgcat
    33061 gacttcccat tcagcagctg atatctgttg cataacgtca ccttcattca caatatattt
    33121 acgtttgtaa attaattata acgaatttaa ctacatttgt aaataaataa cttttctcat
    33181 ttttctatcc ttatattgac aaatgaatcg tttttactat aatattattg caataaaaat
    33241 aacatttaca ttaaggagat acccttgaaa catcctattc gaaaaacact tgtcacctta
    33301 ggtctattac tgaccttatg cctgccgact ccagttgcag ctagttctcg ttcttggaag
    33361 agctggttta tcgagcaata tttctggtta aaacgtgaca agagttacta ttctaaacaa
    33421 gatgacccaa gcttccaaag ataccttgat gcctgtcgtg aacaatctga taaaccttat
    33481 caactagata ctaatttagt caatggtccc cttgttcaag aaaatcttta tggcatgcag
    33541 gtttactctt ggaatgataa tggaaaacct gatcaaaaaa caattattta tcttgccggt
    33601 ggttcttatc ttaacaatcc aacgacatac catattaata tgttaaagac attatccaca
    33661 agtcttgacg ctaaaattgt tttacccatt tatcctaaag ccccacgtta tacctataac
    33721 tatactatgc caaaattggt caatctttac caacactatt accataaaaa tcagaatgtt
    33781 ttccttatgg gagattcagc aggtggaggt ttagccttag gtctagctca tgccctacac
    33841 aatgaatcag tccctcaacc aaagcagctc gttcttttat caccttggtt agatgttact
    33901 atgtcacacc cagagattcc agaatacgaa gatgctgatc ctattctatc ttcttgggga
    33961 ttaaaacgag tgggagaatt gtgggcctac tctgctgata ataccaacca tatttatgtc
    34021 agtcctaaaa atggtccgat cacttatcta ccaccaatta ctttatttac tgggacacga
    34081 gagatctttt atcctgatat tcgcgattat gccgcaaaac tgaaagccgc taaccacaat
    34141 attaccttta ttacccaaga aggcatgaac cacgtttacc caatttatcc tatcgaagag
    34201 gcaaaaacag ctcaatacca aatcattgat gccatcaaca aaactcctta atgaggggaa
    34261 taactcctac ctgccaccag ttaatctggt gttttttttg tagtttgcac cacaaaataa
    34321 caattaaaaa gagccctatc ataatgataa ggctctttct gtcataacat ccgcaccgca
    34381 atacttagga tttgttgtca agatctcgta agagttgatc aattttatta ccataggcga
    34441 tggaattgtc tttttcaaac accaaatctg gaattttgta catggtcaat tgtttgccaa
    34501 gttcacgttt aatcgttcca gtcgcttttt caagccctgt ttgtgctttt tgattatcag
    34561 atgccaagtc actcataata gtgtaataaa ctttagcaag tgacaagtca ccctgcattt
    34621 gcacttctgt aatcgttact ccctgaacgc gtggatcacg cacttttttc tgaagaatat
    34681 catttacttc gcgcttgatt tccatcccaa cgcggtcaat acgatgatta gccatagcca
    34741 tttcctttcc acattttaaa acaaaagcta ggctgaaagc ccagcttatg acattgctac
    34801 ctgttttgat aacgacaatt aaagggaatc tgagaattcc atgacgagac tggaaggaat
    34861 gccccaagta gctcatctgg tagaaaaagt cattatttcc gacagaggaa aaacgttaca
    34921 tctcagacct tcttagcccc tattttctca caatttcttc cataatatag gcttcaatag
    34981 tatcgtcaac tttaagatcg ttaaagtttt caatcatcaa cccaccttct tgagcattac
    35041 cgacttcttt aacgtcatct ttgtaatgtt tcaagctggc cagtttacca tcaaaaataa
    35101 cgacactatc acggataaca cgaacactcg aatcacgtgt caccttaccg ttgattacca
    35161 taaagccacc aattgttccc actttagaaa ctttgaaggt ttcacggata atggcttcac
    35221 caagaatttt ttcttggtaa acagggtcaa gtttcccttt catggcttct tctacttctt
    35281 caatgacttt atagataata ctatgaagac gaatttccac atcatccgta tctgcttgtt
    35341 gacgagcttg tggggtaggg cgaacgttga aaccgataat aacagcattt gatgcttcag
    35401 caagggtcac atcagactca ttgatagcac ctacagcaga gtgaacgaca ttgacacgga
    35461 caccttccac ttcaatcttt acaagagatg ctgcaagggc ttcaacagaa ccttgaacgt
    35521 ctgctttgat gatgacatta acagtcttga tttctcctgc tttaagggta tcaaagagat
    35581 tatcaaggct aacacgctgt gtattttgac gttgtttgag gagggcacgt tttgatcgct
    35641 cctcaccagc tgcacgcgca gctttttcat cagcgtaaac agcaaagtga tcaccagcca
    35701 ttggtgtttc gttcaaacca gtaatggaaa ctggtgttga tggctccgca gatttaacac
    35761 gacgcccaag gtcatttacc atggcacgga cacgaccaaa ggtattacca acaacgattg
    35821 gatcttgaac atgaagagtt ccttgttgga caagaagcgt agcgatagca cctttacctt
    35881 tatctaagcg tgcttcaatt acagtaccaa tagcacgaac cgtcggatca gctttcaatt
    35941 cttccacttc agcaaccaaa aggactgttt ctaatagttc atcaatattt ttattaaatt
    36001 tagcagatat ctctacaaat tcgcactctc cgccccaagc agttgagatg ataccatatt
    36061 ctgccaattc tgcgataaca cgttctggat tagcacctgg tttatcaatt ttgttgatag
    36121 caacaataat tggaacacca gcagcttttg agtgattgat cgcttcaatc gtttgtggca
    36181 taacaccatc atcagctgca acaatcaaaa tggtgatatc ggtaacggaa gctccacgtg
    36241 cgcgcatact tgtaaaggcc gcgtgtccgg gagtatccaa gaaggtaatt ttcttgccag
    36301 cttcttcaat ctggtaagca ccaatatgct gagtaattcc tccagcttct cctgttgcca
    36361 cacgtgagtt acgcaaagta tcaagcaaag ttgtcttacc gtggtctacg tgtcccatga
    36421 tagttacaac aggtgcgcgt tctacaatat tttcaggatt gaggtaattt tcatcctcaa
    36481 agaagcgctc gatatcagca tcatctactt ctaccttagc cttagcctca ataccataat
    36541 ctaccatcaa taattcgata gtgtcaccat ctaaagattg gttttgagtt gccataacac
    36601 ccatcataaa cagcttttta acaatttcag cgggttcgcg tttgatacgt tttgcgattt
    36661 cggcaactgt catgccttca gtatattcaa attcttttgg caattcatgg aatttacgct
    36721 cggttactgg ttttggagcg gtgttggtat tcttaacatt tttgcctttt ttggtctttt
    36781 tatttttatt ccagttacta tttttttgat ttctcacttg gttttgacta ttccaactct
    36841 tcttattttt cttttgtcct tcttgtgaat gatgagttaa ctcacgattc ttttcaggac
    36901 gtgcttgttt tttacggcga ttatcagcag tagatttagc actaatattt gatgacttta
    36961 atttagtttc tgcttcttca atagatttca atgctgcttc acgatggctc atctcctcag
    37021 cttgtgcttt tagagccgct tctttagctt cttgtcttgc caactcagct aaacgcttag
    37081 cttcttgctg tgcacgaaaa cgtgtttcac tttggcgtga gtattcagca ttttgttcag
    37141 cttttaaggc agcagcacga gctttgaaat caattttagg acttttcgat tgaggctctt
    37201 gtcgtccttg ctttttttgg tttgtgaatc gaccattctt gtgattctcc ttagcaaagg
    37261 aacggttacg atcaccaact agctgatgat tatcatgtct aggtgataca ttcgatgctt
    37321 ttcgctcaat acgcttatcg tttgtatcac cttgagaacg atgggtaatc ctcttatctc
    37381 cttgttcgtt agtttgatga ttattgggct ggcgataacc tcctcgacgt tcttgagaac
    37441 gatgagaaga gccatttgct tgttttcgag cagcctgttc ctttgcacga gcctctcttt
    37501 cagctttaaa attacgactc tttggcttag agacctgtgt tttctctaca tgctcagaac
    37561 ctgtttcttt gaccactgtt acagagggtt gagcaacttc tttgggtttg actgtttgag
    37621 aagctgtcac atcaggttta gaagcctttg aaaaacttga aataatcttt ttcgcatccg
    37681 cttcttcaac acttgatgca tggcttttca catctaatcc taagtattta gcgtgttcaa
    37741 ccacctcttt actactttta ccaatttcct tggcaatttc atgtaatctt ttctttgaca
    37801 atttgtgtcc tcctattcat ctattccata agagtcctca ttttctttga aaatccagca
    37861 tctgcaatgg cagcaacctt ccttggttta cctagtgcag cacttaattc cagtgcattc
    37921 aacactgtgg agacttctac attataataa ttacttttat ctgtcacttt ttttgtcaca
    37981 ttaggaccag catcattggc taaaaatact aatattacct gctggtgttg aatagctttt
    38041 actactagtt cttcacctga aatcactttt ccagcccgtt gagctagacc aataagacta
    38101 gataatcttt ctaaattagt caagacctaa ctctcttctt ttgattttgt gatcaacata
    38161 agcaatcaag tcatcgtaaa aactttctgg aatgtccatt gagaaactcc tgttgaaaac
    38221 ttgttttttc ttggccatta aggcctcttg attgtctaat ttgatataag caccacgacc
    38281 attttgttta ccagttggat caatgaaaac ttgaccatcc ttagttttta caatcctaag
    38341 aagatctcgt ttagcaataa tttcaccaga aacaagtgat tttcgtaaag gtattttttt
    38401 gactttagac atcaaacacc tcttttctta tacttcctcg gcagtcataa catcgtcaac
    38461 aactggctct tccacagctg ttgctgcttc tttttccgcc tcaagacgat catattcgct
    38521 agctgatttg atatcaatac ggtagccagt caaatgtgcc gctaaacgaa cattttggcc
    38581 gcgacgcccg atagctaatg ataatttgct atcaggaact actaccgtag cacgtttaag
    38641 atcttcatcg tcaaaaagta ccatgtctac ttcagccgga gcaatggcat tgtagatgaa
    38701 ctcagctgga tcatctaccc attgaatcac gtcaatattt tcttcaactg gaatttcaag
    38761 ccccgtctta gcatctacac gttttggatg gaacttgctg atgacctttt taatattact
    38821 tccaccacgt ccaacaattg ttccgatggc atcaacgtta ggattatgac tgcgcacagc
    38881 aaccttggtg cggtcacctg cttcacgaga aacactcatg atttcaacag taccatcaaa
    38941 gacttcagga atttcttgct ccataatacg tttgatgaat tctggatggc tacgactaac
    39001 aaagacgtta actcctttag gattattttc aactttgtag acataaacgt caatacggtc
    39061 atgtgatttg aaagtttcac ctggaatctg gtcttggtga gacaattgtg cttctaagga
    39121 accaagattg acataaataa aacgttgatc aaaccgttca actgttcctg tcataatttc
    39181 accttcatgc tctttgtatt cattgaacat cacttcacgc atttggcggc gcatcttttc
    39241 cataatagtc tgtttagctg attgagctgc gacacgtcca aattcattga cagattcttc
    39301 aaagcgaatc ttatcaccca attcataggc agaactgata gcaagagcat ctttcaaact
    39361 aatctcaagc cggctgtcaa aaacttcttc aacaacctca cgaaccgtaa atacttgaaa
    39421 atcagctgtt ttttcattaa attcaataac acatgattct gattgaccat agcgacgttt
    39481 ataggcagac tttaatgatt ctgtcactgc gtcaataata tctgctttat caatgtgttt
    39541 ttcttcttcc aaaatacgga aggcttctag catttctttg ctcataatgt tatctacctt
    39601 gcttgtaaag cttggcaaaa atcctttctt aaattaatac gatcaatagc cccctaaagg
    39661 ctcccttaat tccttttgtt tagcttgtat aaactctata ggtgttgttt caaatttgct
    39721 taaatgttcc taaaaaagtt tagtgctttg aaataaaagt tataatttga cagccattct
    39781 caccttagca actgcttgat atggtatatt cacgatctta tgacgtgttt tatcaagata
    39841 atcaatggtc aacgtttcac catcaaaggc taataagtct ccttgaaaaa ctttcacctt
    39901 atcaatagct tgataaagac tcacattgat ataagagcca actgctgctt ttaaactgtc
    39961 agctgtcttg agcggacgct ccaaacctgg actagagact tctagcatat attggtttgg
    40021 aaaaggatct ggatcaatcg tatctaacag cggactaata atattcgtca agtcagatgt
    40081 atcttccact gtgattccac cttccttatc gactaaaata ctaaggatgt agtcactacc
    40141 cattttgtca tactcaacgt ctactaattc ataaggtgcc ttaatctcag gcgttactgt
    40201 cttggttacg atatcgataa tagatgtatt tgctattttg attacctcct ctatttttat
    40261 gctcttctct aagataattg gtccttggga atccacttaa tacaaaagtg gcgagacata
    40321 tcccaccacc tttctgtatt atttaagcct attataccat aatttaagag gaatgcaagg
    40381 atatg
//
LOCUS       DAUGQX010000015        37921 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUGQX010000015 DAUGQX010000000
VERSION     DAUGQX010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37921
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.015"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            39..1235
                     /locus_tag="VIA51_000689"
     CDS             39..1235
                     /locus_tag="VIA51_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8682645.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            1737..2585
                     /locus_tag="VIA51_000690"
     CDS             1737..2585
                     /locus_tag="VIA51_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8682646.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(2921..3817)
                     /locus_tag="VIA51_000691"
     CDS             complement(2921..3817)
                     /locus_tag="VIA51_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEQ8682647.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            4115..4867
                     /locus_tag="VIA51_000692"
     CDS             4115..4867
                     /locus_tag="VIA51_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEQ8682648.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            4852..5802
                     /locus_tag="VIA51_000693"
     CDS             4852..5802
                     /locus_tag="VIA51_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEQ8682649.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADATVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(5980..8307)
                     /gene="pflB"
                     /locus_tag="VIA51_000694"
     CDS             complement(5980..8307)
                     /gene="pflB"
                     /locus_tag="VIA51_000694"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEQ8682650.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            8516..9610
                     /gene="dinB"
                     /locus_tag="VIA51_000695"
     CDS             8516..9610
                     /gene="dinB"
                     /locus_tag="VIA51_000695"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEQ8682651.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVKKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNVKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(9703..10185)
                     /locus_tag="VIA51_000696"
     CDS             complement(9703..10185)
                     /locus_tag="VIA51_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682652.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(10276..12729)
                     /locus_tag="VIA51_000697"
     CDS             complement(10276..12729)
                     /locus_tag="VIA51_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEQ8682653.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFALQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(12787..13380)
                     /gene="lepB"
                     /locus_tag="VIA51_000698"
     CDS             complement(12787..13380)
                     /gene="lepB"
                     /locus_tag="VIA51_000698"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8682654.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(13391..14293)
                     /locus_tag="VIA51_000699"
     CDS             complement(13391..14293)
                     /locus_tag="VIA51_000699"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEQ8682655.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            14450..14758
                     /locus_tag="VIA51_000700"
     CDS             14450..14758
                     /locus_tag="VIA51_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682656.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            14761..15306
                     /locus_tag="VIA51_000701"
     CDS             14761..15306
                     /locus_tag="VIA51_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEQ8682657.1"
                     /translation="MLSLLIVLILTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLNYFDNQWTKCLSGGLAFLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLTRL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            15455..17794
                     /locus_tag="VIA51_000702"
     CDS             15455..17794
                     /locus_tag="VIA51_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEQ8682658.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSTDLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINNGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADGSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG"
     gene            17798..18298
                     /locus_tag="VIA51_000703"
     CDS             17798..18298
                     /locus_tag="VIA51_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8682659.1"
                     /translation="MESYEHFYAKLSQPFRKTPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSALLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            18379..18693
                     /gene="trxA"
                     /locus_tag="VIA51_000704"
     CDS             18379..18693
                     /gene="trxA"
                     /locus_tag="VIA51_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEQ8682660.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(18745..19332)
                     /locus_tag="VIA51_000705"
     CDS             complement(18745..19332)
                     /locus_tag="VIA51_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682661.1"
                     /translation="MEIGQQIIRYRKQQALSQEKLAEKVYVSRQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSNGKLLDEIEKREE
                     RATLPYQKPLIVTVFFLITVAFAFASRFMFTWLFH"
     gene            complement(19408..20532)
                     /gene="mutY"
                     /locus_tag="VIA51_000706"
     CDS             complement(19408..20532)
                     /gene="mutY"
                     /locus_tag="VIA51_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEQ8682662.1"
                     /translation="MWDNETIASFRRTLLEWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            20730..21023
                     /locus_tag="VIA51_000707"
     CDS             20730..21023
                     /locus_tag="VIA51_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682663.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            21196..21486
                     /locus_tag="VIA51_000708"
     CDS             21196..21486
                     /locus_tag="VIA51_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEQ8682664.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            21508..21999
                     /locus_tag="VIA51_000709"
     CDS             21508..21999
                     /locus_tag="VIA51_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8682665.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            22164..22403
                     /locus_tag="VIA51_000710"
     CDS             22164..22403
                     /locus_tag="VIA51_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEQ8682666.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(22536..23192)
                     /locus_tag="VIA51_000711"
     CDS             complement(22536..23192)
                     /locus_tag="VIA51_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEQ8682667.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQKAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(23325..24269)
                     /locus_tag="VIA51_000712"
     CDS             complement(23325..24269)
                     /locus_tag="VIA51_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEQ8682668.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            24472..27300
                     /gene="uvrA"
                     /locus_tag="VIA51_000713"
     CDS             24472..27300
                     /gene="uvrA"
                     /locus_tag="VIA51_000713"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEQ8682669.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEITASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKGKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGDGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            27415..28488
                     /locus_tag="VIA51_000714"
     CDS             27415..28488
                     /locus_tag="VIA51_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8682670.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDASEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYLSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSRFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            28523..28984
                     /locus_tag="VIA51_000715"
     CDS             28523..28984
                     /locus_tag="VIA51_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEQ8682671.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            29080..29637
                     /gene="efp"
                     /locus_tag="VIA51_000716"
     CDS             29080..29637
                     /gene="efp"
                     /locus_tag="VIA51_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEQ8682672.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            29683..30072
                     /locus_tag="VIA51_000717"
     CDS             29683..30072
                     /locus_tag="VIA51_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8682673.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            30065..30517
                     /gene="nusB"
                     /locus_tag="VIA51_000718"
     CDS             30065..30517
                     /gene="nusB"
                     /locus_tag="VIA51_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEQ8682674.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSGAPSANKS"
     gene            complement(30658..31623)
                     /locus_tag="VIA51_000719"
     CDS             complement(30658..31623)
                     /locus_tag="VIA51_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8682675.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(31628..33067)
                     /locus_tag="VIA51_000720"
     CDS             complement(31628..33067)
                     /locus_tag="VIA51_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEQ8682676.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTHGQTGIQVVEGQAFGHYYEMRY"
     gene            33309..35192
                     /locus_tag="VIA51_000721"
     CDS             33309..35192
                     /locus_tag="VIA51_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8682677.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKHGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLSAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            35423..>37921
                     /locus_tag="VIA51_000722"
     CDS             35423..>37921
                     /locus_tag="VIA51_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8682678.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KGLPSIDSLHYLSENSKKEFKEELSKAGQESQKVKEILAKAQQADKQAQELAKMKIPE
                     KIPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLF
                     WKELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDVEHDSIPKVDKKEDTAGVERSIQVFEEIGKLIGPKGVDKSRLF
                     IMDSTYMADKNPLIERGAPYINLLLVQVYGSQGEKGGWEPVSNRPEKTMEERWQGYSK
                     YIRPEQYMIGFSFYEENAQEGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKT
                     GGVKGGIFSYAIDRDGVAHQPKKYAKQKEFKDATDNIFHSDYSVSKALKTVMLKDKSY
                     DLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNKFKKLAQLD
                     LIGLSRITKLDRSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLKVSGLTGLK
                     ELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLSTISNHVGS
                     NEQTVKFDKQKPTGHYPDTYGKTSLRLPVANEKVDLQSQLLFGTVTNQGTLINSEADY
                     KAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATDKEETYKVD
                     FFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFDGQLGSETDN
                     ISLGWDSKQSIIFKLKEDGLIKHWRFFNDSARNPE"
BASE COUNT        11475 a         6725 c         8009 g        11712 t
ORIGIN      
        1 gtaaaatgtt tatgaaaata gagaggagtt cattttcaat ggaagaaaaa ttgtttaaca
       61 aacattttgt ggccatcaca gtaataaact ttatagtcta tatggtctac tatcttttta
      121 cagttattat tgcctttgtg gcgactagag agctaggagc tcagactagc caggcaggat
      181 tggcaacagg gatttatatt ctagggactt tattagcccg tttgattttt ggaaagcagt
      241 tggaggtgtt tggtcgtcgt ttggttttaa gaggaggtgc tattttttac ctcttaacga
      301 ccttagccta cttttatatg ccaacgatta gcatgatgta cttggttcgt ttcttgaacg
      361 gatttggtta tggtgtagta tcaactgcga caaataccat tgtaacagcc tatattccag
      421 ctcgtaaaag aggagaagga attaattttt atggcttgtc aaccagtcta gcagcagcta
      481 ttggcccttt tgtaggaacc tttatgttgg ataatcttca tattgatttt cgcatgatta
      541 ttgtcttatg tagcgtcttg attgggtgtg tggttgttgg tgcttttgct tttccagtca
      601 aaaacatgtc tttaaatgcg gagcaattgg ctaaaaccaa atcgtggact gtggatagtt
      661 tcattgagaa aaaagccttg tttatcactg caatcgcctt tttaatgggg attgcctatg
      721 cttcagtttt aggatttcaa aaattataca cgtctgaaat tcatttgaca acagtaggcg
      781 cttatttctt tgtggtctat gccttaatca ttaccatcac tcgtccagca atgggacgtt
      841 taatggatgc taaaggcgat aaatgggtct tgtacccaag ttatcttttt ttagcaatgg
      901 gactcttctt gctaggtagt gtatcgtctg gaggaagcta tttgctttca ggagccttga
      961 ttggctttgg ttatggcact tttatgtctt gtggtcaagc cgcctccata caaggagtgg
     1021 atgagcaccg ctttaatacg gctatgtcta cttatatgat tggtcttgat ttaggtttag
     1081 gtgctgggcc ttacctcttg ggcttgatta aagatttggc acttggtagt ggtgtggctt
     1141 cctttaggca cttattctgg ttagctgctg tgattccact gatttgtacc ttgctttact
     1201 tgttaaaaac aaagacaaga caggttgtgt cttaaggaca agaaaaggag tttagtctta
     1261 tacttaaata caaacgtatc ttaacagctg tagatagttc ctatgagccg ggattagctg
     1321 tgggtaaagc cattactata gcgctttgaa ataatcctag tttgctattg gtacatgtca
     1381 ataaaaatga ctcgcaaaag ccattcgtga aagagaaaat gtggccttat ttttagtagg
     1441 tacaattgga ttaagcacgt ttagatacat gacaattgga ttaacatcag aatataggct
     1501 ttgtcatgtt aagattgatc tgttgatagt gagagctaat aaaaaatgtt ataatactat
     1561 gaaataaagt gataaagata aggcctttta tggtcctttt ctttaccgct tttattattg
     1621 tgtgaaaata acacttaatg atcattttat ttattatttt attaccttta cattcatcaa
     1681 taagcctgtt aaaatggtat ttgttatatt ttattatttg gaggaaacca gaaaacatgg
     1741 aaatgacatg gactgtgaaa tacatcacag aatttatcgc aacggctttt ttgattattt
     1801 tgggaaatgg agctgttgct aacgtcgact taaaaggaac aaaaggacat aactcaggtt
     1861 ggttagtgat tgcttttggc tatggcttag gagttatgat gccagctttg atgtttggta
     1921 atgtatctgg aaaccatatt aatcctgctt tcacagttgg actagcagta tcaggcttgt
     1981 tcccatgggc tcacgtctta caatacgttg tggcacaatt acttggagct atctttggtc
     2041 agttggtagt ggtaatggtt tataaacctt actttatgaa aactgaaaat ccaaatcatg
     2101 ttttaggctc attctcaacg atttcatctc ttgataatgg tcaaaaagac agtcataaag
     2161 cctcttatat caatggtttc ttaaacgaat ttgtaggttc atttgttctt ttctttggtg
     2221 ctttggcttt gactaaaaac tactttgggg tagagttagt tggtaaattg attgaagcag
     2281 gctacgacca aacaactgca gcaacacaaa tttcaccata cgtgacaggc tcattggcgg
     2341 ttgctcacat tggtattggt ttcttagtta tggtcttggt tacttcatta ggtggaccaa
     2401 ctgggccagc actaaaccca gcgcgtgatt ttgggcctcg tttgttacac cacttcttac
     2461 caaaatcagt tcttggtcaa gccaaaggtg attcaaaatg gtggtatgca tgggttcctg
     2521 tagttgcacc tatcttagcg gcgatagtag ccgtagcagc gtttaaatac ctttatatca
     2581 gataaaaaaa gaactaaagc ttcttttaga ctcaagacaa gctcgcttaa ggaacttgtc
     2641 ttttttatat gagttaagcg aaatctaata caaacttgac tgtcttgtat agcgtatttt
     2701 gtaaatttta ttagacttct tgtaaaaagc ctctcctcag ataagatgac taatgcctct
     2761 aaacggtgtt acaaataaac gaggcatctc taacttcctt tatctggtgt tgaaactatt
     2821 ttgcacggac taaatcactg atagagtcaa aaaacaattt ttcatttttg ttgtaaaata
     2881 ttaaaaacgt ctctggttag tgattcccag aaacgttatc ttatctattt gtttgttgct
     2941 tatgagaggt aaaggaggaa cgaatcagca ttccaccagt gaagaaaacg atagcgatga
     3001 ccagaagttt caagctatta atatctaaat tcgttaagaa aaacacagct agtaaaacgc
     3061 caataatacc accagaaaca attccagcaa aaccatccca actgacacgg tttgctttga
     3121 taaactggct actagaagct gtcataatca tagctgcatc tagcatcata acaggcatag
     3181 caactgttgg gctaagaccc attaatgaaa agaaaatcaa ttctggagca taattgccta
     3241 accccatagt catcaagact ccaacgataa aattaaaacc aattccaaca aaaagccaga
     3301 tgccatggag gccatgaatg gtgtctgaaa ggtgttctcc tggatggtag attattctaa
     3361 tgatcatgat tatagctgct atgattaaaa gactaccaag gattcgttgg acagttggag
     3421 catgccagtt ttttgtaata tgagtcccaa aataagctcc aataaaggct gctgcagcca
     3481 tagcaagtaa agttagaacc tcaactttta cgacaaaaat aaagcaaaga gattgaatga
     3541 gcaccggaag cacatgagct acggtcatag tgccaggcaa ttgtctatcg tcagtgacta
     3601 atttagttaa cttaaagcac gttgtggtag tagcaaaaga ccctatccca agggtgtcaa
     3661 gggcatctgt tagcaggcca atccaaaacc ccgtccaaaa gcgtttaaaa ggattgatct
     3721 tatttttttt aagatgtttt actaacataa agaaaataaa aagcattgcc gaaactagca
     3781 aagcttgtat cagtctaagg ataagcattt cgttcataaa gactagttta caaaaaaaaa
     3841 ccttagccgt caacgtgatt tacttcatta aaacatgcca ctatgcttag aagagcttta
     3901 gttcgatgta ttttgttaaa attaagctaa aatattaata ttgcatgaaa ggggacgcct
     3961 tcctttttcc cttactgagc ttagctgtta ttgtagtgaa tgtttaaaag gctagtttgt
     4021 cgctctttat caaaaatcta gtaggatgaa tacgtataat ttcttgtcaa atagaggaat
     4081 tttgtctata atagcagagg attaggagga aattatgact ttaatggaaa atattacctt
     4141 taaaactcca gtattacgcg ttaatgatcg cgaccttaat attgcatttt atcaaaataa
     4201 tttagggctt cgtttagtat ctgaagaaaa tgcgattgct atcttttcat cttggggaga
     4261 agggcaggaa tgttttgtaa ttgaagagtc accttcagtt agaacgcgtg cggtagaagg
     4321 ccctaaaaag gttaatacga ttgtcatcaa aacaaatcaa cctaaagaaa tcgaacaatt
     4381 attagctcat ggagcacatt atgacgctct ttttaaaggt caaaatggct atgcctttga
     4441 gactatttcc ccagaaggag accgattctt gttgcatgct gaacaagata ttaaacatct
     4501 ccaaggtact gatttaccat cgcttgaaaa agatgcgact tttaaaggtt taactcaatt
     4561 taagtttgat attattgttt taaatgttat tagtgaagaa cgctcaaaag ctttttatcg
     4621 ggatctgttt agtgatcagt tacctattac tatggatttt attcaagaag aaggtcccga
     4681 tttggcaatt gatccccata ttgcttggga tttagaaatt ttagaatttc aagtctcaaa
     4741 ggactatgat atgaaggtcc taaaagcaac tttagaagaa gacgggcaca aggtctacat
     4801 tgataaaaaa cacaaagtat tggtcctttc tgatccaagt cagatcgaag tatggtttac
     4861 gaaatgactt tggcggtcat taaatgtatt gaaaaccatc ttcacaaaaa agtatacaaa
     4921 ggggccagtc tggctctctt tcaatctggt cgatggcaag aataccatat cggaacaatt
     4981 gatggaagac gaccagttga tgctaactta gtttatgact tggctagtgt ttcaaaagtt
     5041 gttggtgtgg ccacaatatg caatatttta ttgaataatg gtacgttagc attagatgat
     5101 cccttaaagg tatattatcc tagtattgct gatgcgactg tcactattcg acagttattg
     5161 actcatacca gtggtcttga tccttatatt cctaacagag atgttttaaa tgcacaacaa
     5221 ttaagaaaag cacttaatca tcttactcaa aaagaaaata aaaactttta ttacacagat
     5281 gtcaatttcc tcttgttagg cttcatgtta gaagagctct ttagtgaatc tttagaccag
     5341 atatttgaca agactatctt tactcccttt gggatgtatc atacgtcttt tggccctcgt
     5401 ccagaagctg taccaacatt aaagggtgtg agtgatggag aagttcatga tcccaaagca
     5461 aaaatcttaa aaaaacattc tggatctgcg gggctatttt caactcttgc agatttagaa
     5521 agttttagca atcattatct taatgatcca ttttcagatt gtctgtggcg caactacagc
     5581 caacaaacaa ttgagcggtc actagggtgg aatttagatg gcgattggat tagtcataca
     5641 ggttacacag ggccgtttct aatgcttaat aaaaaagagc aaacggcagc tatttttttg
     5701 accaaccgta cttacgacga ggatgataaa agtaaatggt taaaagaacg tcagttgctt
     5761 tacaatgcac taaagcatga tctgacaacc cccgtatcgt aacgtctaaa ggggcagttt
     5821 tagtgatctt attactgttt ttaaagtttc ttctaaaata gccatttcat ttgtctgatg
     5881 cgattagagt gattataagt gaaaaaagaa tagccatctc attttgaatc aaatgagatg
     5941 gctgttcttt tttataagtt attgatcatt tagatactac tatttacttg aaatagcttc
     6001 agcagcatcg tccatggaaa gcacttcgtg gaagacacgt tgtgtcaatt cagttttttg
     6061 ttctggtgta aggtatttgg tgttgacaca gtaaccagag atacgtacga taacgtcttc
     6121 gccgttcatg attttgtcat aaacatcgtt aaggtccata acgttcaagt taacgtgctg
     6181 accaccattt tcaaagtaac cgtcaagcac tgttaccaag ttgtcaactt gttcgtcaaa
     6241 tgttttacca agagcacgag gtgatacttg agtagtcaat gagataccat cgttagcatg
     6301 tgagaattcc agtttagcaa gtgagttaag gttttgtaac cagccacctt ttgctttgtt
     6361 agatgggtta gcacctggtg agaagaattc cacttggcta gtgttaactg taccatcttc
     6421 gtttaagaag acgccgcggt gaactggaga gttaccagtt tgtttagagt aagcaacgtt
     6481 tgaagtgatg gtaagaagtg atactgaagc ctcagcattc ttgtaaagtt tgtggcttgc
     6541 aagacgtgtg tggtaagctt ccatcaacca tttcgcgatg tcatcaacac ggtcgtcatc
     6601 ttcaccgtaa cgagggaagt cacctgttac ttcgtagtca tagatgtagc cattttcatc
     6661 gcggatagtt ttaacagttg cgtatttaat agctgacaag gtatcaactg tgttagcgaa
     6721 accacagata ccgaatccca tgttagcacg ttggtgtgtt ggcaagaagg ccatttgaac
     6781 tgcttcgtag ttgtatttat cagtcatgta gtggatgatg ttaagcgcat ctacataagt
     6841 atctgtcaac cagtcaagag atttctcaaa gttagccata acttcgtcgt actcaagaac
     6901 ttctgatgtg attggttcaa caacgttaaa cactttgtag tctctgtgaa catcatcgta
     6961 accaccgtta agaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtattg
     7021 gatgttatga cgttgttctt cattttctgg gtcaagtggt gacacacaac atgaaataca
     7081 tgacatttca ccataacctt ctttagccat tgttgtcaca ccttcatatt ggatagaaga
     7141 gtgcttgtgg ctcattttca tacagtagcg acggaatgtt tctggcagtt ggtcagtcca
     7201 aagaacagtc aagtttggtt ctggagagtt accaatatta tcaagcgtgt tcaagaaacg
     7261 gtagtccatc ttagttacac ggtgacgacc atcgttaccc ataccagcca tagaagttgt
     7321 gatgaatgtt gggtcacctg agtaaagcgc atcgtaagct ttcgtacgac caaattttac
     7381 ggtacggagt ttaaggacaa aatcatcaac aaattcttgg atttctgatt ctgtaaaggt
     7441 accgcgagca aggtcacgtt ctgcaaagat atcaagaacg attggcacac gtccaagaga
     7501 agtagcagca ccgttgatca cacgacatac agccatgaaa gcgatgttta cccattggat
     7561 agcttcttta acgttttgtg ctgggcgacg aacatcaact ccgtaaaggt caccaagttt
     7621 aaccacttca ccaagagctt ggtattgaag gttaacttct tcgcgaagac gaatggattc
     7681 ttcatcgatt tcagtgatag cattccagtc attgactttt tcttgcatca agtagtcagc
     7741 accgtaaaga gcaagacgag cgtaaacacc gatgatacgt ccacgtgagt aagcatctgg
     7801 aagaccagtt acagtgtggg catgacgagc gcgacgaata tttgaagtat aagcgcggaa
     7861 gataccgtcg ttaacagttg tcacatactt agtaaagatt tcatgtactg ctgggtctgg
     7921 ttcatagccg ttttctttaa gggtcgtttc cgccatacgg ataccacctt ttggcatgaa
     7981 gttcaatttg aacaattcat cgttttgaat accataaatt aattcatttt ctttatcgat
     8041 gaaaccagca ggaatgtcag caattgaagt tggacgagta tcgtatggga aacgtgtagc
     8101 ttcatagtgt gcttttgttt cttcgataac ttttttgatg tgaagtgaac gttcagtagc
     8161 accagccaag aaagattcat cgccatcgta tggggtgtag ttagcttgta caaaacgtga
     8221 gacacttgct ttttctttcc agtcagttcc tttaaagcct tcccaagctt tttcgaaaac
     8281 atctgtattg gttttaacag ttgccataaa tttctcctta aattctagta acaaagcgat
     8341 ctgttacatt tacaattcta agtttaacac ataggaaacg ttttcccaag caaaattctt
     8401 gacaaaatta agattctttt ataatacaga ttgttgaaac agtcacaaac tgtattagaa
     8461 tgtatttttt tggctttaga tagcctaaaa ggtataatag agaaaggagg gacttatgct
     8521 tatttttcca ctgattaatg acacgtcacg aaaaatcatc catattgaca tggatgcctt
     8581 ttttgctgca gttgaggaaa gggataaccc tgctttaaaa ggaaagcctg ttgtgattgg
     8641 gaaagatcca agagaaacag gtggtcgcgg agttgtttcc acttgtaatt acgaagcgag
     8701 aaaatatggc attcattcgg ccatgagctc taaggaagct tatgagcgtt gtcccaaagc
     8761 catttttatt tcaggaaatt atgaaaagta tcgaacagtt ggagaccaga tccgccgtat
     8821 ttttaagcgt tatactgatg tggtagagcc tatgtccatt gacgaggctt accttgatgt
     8881 gactgataat aagttgggga ttaagtcagc cgtcaaaata gccaagctga ttcagcatga
     8941 tatctggaaa gaagtaggat tgacctgttc agcaggtgtg tcttataaca aatttttggc
     9001 taaattggct agtgattttg aaaaacctca tggcctcact ctagtcttga aagaagatgc
     9061 cctgtgcttt ttagccaaac tccccattga aaagtttcat ggtgttggta aaaaatcagt
     9121 taaaaaactg catgacatgg ggatttatac aggacaggat ttgttggcag ttcctgaaat
     9181 gaccttgatt gatcattttg gtcggtttgg ttttgacctt taccgtaaag cgagaggcat
     9241 cagcaattct cctgtcaagt ctgatcggat acgcaagtca attggcagtg agagaaccta
     9301 cgctaaactg ctttatcaag aaacagacat caaggcagag atcagtaaaa atgttaagcg
     9361 cgtggccgct ctcttacaag accataaaaa gttaggcaag accattgtgc tcaaagtgcg
     9421 ttatgctgat tttaccacct tgacaaaacg tgtcaccttg ccagaattaa ccagaaatgc
     9481 cgcacaaatt gagcaagtag ctggggatat ttttgacagc ttaagcgaaa atcctgctgg
     9541 tatccgcctg ttaggggtaa ccatgaccaa tttggaggat aaggtagctg atatttcctt
     9601 ggacctatag gagaaagagt gctctatccg tccgcctcat tttggagaaa aaagaagctg
     9661 attagggatt tccctaatca gcttctttgg tccattattt tattacagca tagcttggtc
     9721 tgtatcatca cctttttcgt taagggtttt agccttgtaa aaagcaaagc cataaagagc
     9781 agcttgtata aggataagga tagttccaac cattgacatg gttgttgtga actggttaac
     9841 caagccgata acagaaagga taaggcctaa gatataagga atataactaa ccgttagacc
     9901 ttgttttaat ttagataagt tttgagcaca aaagacaatg atagcaataa tagcaaggac
     9961 atttaagaca gataagaaaa tcataaatgg tgtcatgctg ctttgtagct gtgccaattg
    10021 ctcagttgtt aattgggccc gaaatgcttc attcttgagt tggctttgta agtagaaaat
    10081 ccctgcaaat cccattaatg acagtacaac tccaagcccg tttagaataa taatggcaat
    10141 agtagacgtt ttgagtgcct gacgcacttt ttcataagaa atcatataat cctcctagag
    10201 tccttaatcc gaaattgtac aatgtgttta atacaaaaat attataccat agattaatca
    10261 aaaatgtccg tttttctagg attttttctg gaaaaagagg gcaatatctg attctgtaag
    10321 ccctatcatc gaatcgatag tcgaataatt ctcaggtgtt aacctaaaat catcattatc
    10381 tgactgagag ttctcagtgg ggttagagtt tgttgattga gaggaagatt tttgagagtc
    10441 gtcctcaagg gttgccgtat tagaaaaaag ggaggtctgc tcttttgatt ttagctcttg
    10501 gttaggttga gaggaggcta agtcggattg ttcttggaag cgttcgatca agtaggtttg
    10561 gcgtttatcg ccttcgtgtt taatagcata ctcaaaggca gtatattctc ccaacagaat
    10621 taacttactt ttagaccgag taatggccgt gtaaatcaca tttcgttgca agagtcggcc
    10681 gctttggcgt gtgataggta aaatcaccac ttgaaactca ctcccttgcg atttatgaat
    10741 gctcatggca taggccaggg ttaattttag ccattcattt ctagggtacg tgacttcgct
    10801 accgtcaaaa tctaagatta attcgtcttg cttagattcg gtgtatttag caggaatcaa
    10861 atctgtaata taaccaatat ctccgttaaa gacattcaac tgagcatcgt tgactaagtg
    10921 caggacttta tcacctttac gaaaatgcgt atcattgaac agaaattctg tttgtccttg
    10981 caagggattg agaagttctt gcatgagttg attaagatga ttgatgccag cttgtccttt
    11041 gtacataggt gctaaaattt gaatttcctc agcagggatg ccacttttaa tagcagatag
    11101 gacaattttt tgaatcatgt cagggataaa ggctgcttgg gcttcaaaat aagaacggtc
    11161 agctttttta tcacgaaagt cagcagctaa gattcctcga cgcatctggt ctgccaaatt
    11221 gacaatagta gattcttggg attgacgaaa tatcttttgc aaggcgattt ggggcaggct
    11281 attgactttt aaaagatctg acaggacttg accgggtcca accgaaggaa gctggtcact
    11341 atctccgaca ataatcactt gagttgttga gttaatagct cctaacaact ggttggcaag
    11401 ccaggtatcc accattgaaa attcatcgac aatcagcagg tcgcagtcta gataatcctc
    11461 catggcttgg taatcgttgt cgccattgag gcctaagtgc ctgtggatgg ttgcgctagg
    11521 aagtccagtc aactcattca tgcgacgtgc agcccgacct gttggagctg ctaacaagat
    11581 aggaaggtct tttttatcca aatcaatctg atgcaggttc gcgtaagcct gcaaaatgcc
    11641 tcgaataaca gttgtttttc ctgttccggg accacctgtt aggagaaaga ccttgctggt
    11701 taaagcctta gtaatggctt cttgctgcac ttggtcatag gtgatggcaa agtctttttg
    11761 aacggcttgg atggttgttt gaatggtatc atgactaaat gactgactta aaggagtatc
    11821 taagagacga gagatgttgt tagcaatccc ttcttcagca aaataaaggc tagcatcaaa
    11881 cagtttggtg tcactgtttt tgattttgcc ctctatgatt aactcgctta gttgttcagc
    11941 cacagcagca ggatcacatt ctacttgacg tgcatcttca aggagtgtga tggcaaagtc
    12001 taataattgt cgtgcttgga cataagtatc tcctcgattg atggattctt ccaagagaca
    12061 gtgaaggagg gctgcacgaa aacgtttcgg agagtcgctt tcaatcccta agttttcagc
    12121 gagagcatct gccattttaa acccaaaacc ttgtagatct tcgactaact gatagggatt
    12181 ttctttaaca aggtcaagag cctcttcttt atacttttca aacgcttgaa gggcaaaacg
    12241 gttgctaagg ccaagttcga cgagaccagc aatcagttgc tctgtgccgt aattcaattt
    12301 tagtttagcg acaaaggctt gacgattagc cttagatagg ccagagatag tttctaattt
    12361 gcttgggtct tctaaaatat ggtcaatggt attatgacca tatagcgcaa tgattttctc
    12421 cgctgttttt ttaccaatcc ccttaaaatg gtcgctagag aaataattaa ccaaaccaga
    12481 tgaactaggt ttgatttttt ggtaacggct tagtttgagt tgctgtccat atttagggtg
    12541 ctgggtcaat tccccccaaa aggtgtagtc atctccttca ataatgtcag ccatcgttcc
    12601 tgtgataatg atttcaaagt cgtcaatgtc actgtctgta tcctcaatgg caaggaggag
    12661 aattttaaag aaattagcct ggttttcaaa aatgatacga tcaacagtac ctgtaaaaac
    12721 gtattccata gtaactcttt ctatttatac aagataactg aaaacctgcc caaaggcagg
    12781 ttttttctaa ttaaaaacgg tcattttatt gagtggccaa aaacgagctt tcacttcacc
    12841 gataaggttt tcttttttga aactaccaac ttcgcgacta tccctggaaa caatacgatc
    12901 atcaccaaga agaaggtatt ctccttttgg aacactcatc tcaaagcgtg tttgtccctc
    12961 agaattagtt gtaaaagcat cagatgtttc tgctaactgt tggaataggg tattataggc
    13021 gtaagttttt tggagtttat cgtttttaaa ttgttttaga tactcagcca aatacggctc
    13081 aactgttttt ttaccattaa tataaagtgt gtcatcatta taagaaatgg tatcgcctgg
    13141 caatccaata actcttttta cgatttcttt cttttgtccg ttttcttctt cctgagcaac
    13201 tacaatatca aagcgatcaa ttctagcttg attaaaaacg ataaggcgtt cgccatgagc
    13261 tagagttggg tccatagaat ggccgtctac tttaacagcc tgccacaaaa aaagacgaga
    13321 tagaccaaag agaattaaaa agagagtgaa tgggccccat tctttaataa actgtttcat
    13381 atgattcctt ttatttagtg agaagcgctt gcgctttgtg agtgttggcg aagtgaagtt
    13441 tagcactata ttctaagcta gacataccat aagcggctaa gagttggcta gcaactttat
    13501 ctgaagctga accagcaccg cttgggagtt ggtaacctaa atcttgacct aattgatcga
    13561 gattgtctaa aaatagattt ctagcaatga tagagctaac agccacagcc aaatagtgac
    13621 tttctgcctt ttcttgaaag gttagaggat ttgggaaatg gtttttttcc ttttttagat
    13681 gcttttcata atttgattgg ctagtgaaag catcaataac aatttgttta ggttgaatgc
    13741 ctttttgtaa caacaaaaaa atagcttggt tatgaagagc aactttgata gaaatggcat
    13801 tatatggttt acttttacca accaattcgt tatatttttt aggtgatagg agaagtgatt
    13861 gatgaggtat ttgtttctct aacagaggcg caatctgttg aatggtttta tccgataatt
    13921 ttttagaatc atcaacccca agctttttca ggaaggaatg atctttagga tcgacaaaac
    13981 ttgccacaac agcaatccca ccaaaataag agccattacc cacctcatca ctgccgatta
    14041 taggtatatc ttggctattg ttgcttgctt caaaaactgt cttagctact ggaagattaa
    14101 gctcttgagc taaagcattt gcaccgtttc cctggagaac taattttccg gatttgtaca
    14161 gcaaaacagt aaccccattt tttttagcag caaaggctac ataggtattt tggctactga
    14221 tggtgtaggg ggctagctgt ttttttaaat gtttactcag tatagcatct attttcaaaa
    14281 ctaaggtatt cataataatt attttaacat aaaatagttg actatggtta attcataagt
    14341 ttatttaaca aagaaaacag agactcgaat gtttagacgg gttagggcaa tggtgttgac
    14401 tattttacga aagtttcatt ttacggtata atgctaatga ggtgacccta tgaaaagtat
    14461 taatcgctat aaattcacct ttggtgaaaa aacattaaca ttgacaactg acaaagacaa
    14521 tctctttatg gaagaagttg agcgggtagc taaagaaaag tatcaggctc ttaaaaatca
    14581 tttaccagaa gctgatgacg agactatcgc tattttaatg gctatcaata ccttgtcaac
    14641 acaattaagc agagagattg ccattgaaaa aatggaagct gaaattttag atttacgtca
    14701 aaaaaccttg gttggtcttc aagaaaaagc taatcaaata gatgtgaatg aggtttaatc
    14761 atgttatctt tattgatagt gcttatttta acttggaatt tttatattgg ttatagtaga
    14821 ggtattattc ttcaatcgtt ttatgtctta ggagccctac tttctctttt ggtagctaat
    14881 cgattttata ttggattagc ccataagcta acgctttgga ttccttattc taacccggta
    14941 gaaggaacat cagtcttttt ctttaaatca gttgatatct ttgttttaga taaggtttat
    15001 tatgcaggcc ttgccttttt tatcattttc ttattggggt atgcattgag tcgctttctt
    15061 gggatttttg ttcatttcct tttgctaaat tattttgata accagtggac aaaatgtttg
    15121 agtggcggac tagcgtttct agtatcgctt ctttttttga acatgttact gtctattttt
    15181 gcaacggtcc ctatgccttt tttacagcac tatttgcact ctagttttct tactcgtttg
    15241 gtgatcgaac accttccacc attgacaata attattcaaa aattgtggat tcaagccatt
    15301 atttgatatc gttttgtgac taatataaga acctggagtg agtttcacct ttaggttctt
    15361 tatttacgag aaactgttta gaaataaaga gaacgcatgg gaacttagtg actttcttgc
    15421 cccattttcc atcattttag gtataatgaa gagtatgaat aacaagattt tagagcagtt
    15481 agaatttaac aaagttaagg aattgctatt accttatctc aagacagaac aatcacaaga
    15541 agaattatta gagctggagc cgatgacgga ggctcctaaa atagaaaaaa gttttaatga
    15601 aatttctgac atggaacaga tttttgttga acatcactca tttggcatag tcagcctaag
    15661 ttcaatctct gagagtttaa aacgcttaga gctttcaact gatcttaata ttcaagaact
    15721 tttggctatc aaaaaagttt tacagagttc ttcggatatg attcactttt attctgattt
    15781 ggataatgtt tctttccaat ctttggatcg tttgtttgaa aatttggaac aattccctaa
    15841 tctgcaaggg tcttttcaag ctatcaataa tggtggtttt ttagaacatt ttgcgagtcc
    15901 agaattagag cgtatccgtc gtcaattaac aaatagtgaa cgacgggttc gtcagatttt
    15961 acaggatatg cttaaggaaa aagcagagct tttatcagag aatctaatcg ctagtcgtag
    16021 tggacgaagt gtcctaccag taaaaaatac ttatcggaat cgtatttctg gtgtggttca
    16081 tgacatctct tcttcaggaa gtactgttta tattgagcct cgtgctgtag ttacactaaa
    16141 cgaagagata acgcagctta gagctgacga acgccacgaa gaaggtcgta ttttacacgc
    16201 attttcagac ttgttaagac ctcatgtcgc cactattaga aataatgcat ggattcttgg
    16261 gcatcttgat tttgtaaggg ctaaatatct ttttatgtct gataataagg cgacgatacc
    16321 taagatttct aatgacagca cgttagcatt aatcaatgtt cgtcatcctc tgttaagtaa
    16381 tcctgtggct aatgacttac attttgatca cgatttaact gcaattgtca tcactggtcc
    16441 caatactggt ggtaagacga ttatgctaaa aacactcggt ttagcacaat taatgggaca
    16501 gtctggtttg ccagtattag cggataaagg tagtaaaatt gcagtattta acaatatctt
    16561 tgcagatatt ggcgatgagc aatctattga acaaagtcta tcaacttttt ctagtcatat
    16621 gacgcacata gtcagtattt taaacgaggc tgaccacaat agtttagttc tctttgatga
    16681 actaggagca ggaacggatc ctcaagaagg tgctagtttg gccatggcta ttttagaaca
    16741 ccttaggtta agtcatatca aaacgatggc gaccacgcac tatccagaat taaaagctta
    16801 tgggattgag acaaattttg tagagaatgc gagcatggaa tttgatgcag aaacgcttag
    16861 ccccacatat cgctttatgc aaggagttcc tggacgctca aatgcatttg aaattgcttc
    16921 tcgccttggt ttagctccat ttattgttaa acaagctaag cagatgacag attctgactc
    16981 agatgttaac cgtattattg aacagttaga ggcacagaca cttgagacac gtagaagact
    17041 ggatcatatt aaagaagttg aacaagaaaa cctcaaattc aatcgtgcgg ttaagaaact
    17101 ctataatgaa ttttcacatg aacgcgataa agagttagaa aaaatctatc aagaagctca
    17161 agaaattgta gatatggctt tgaatgagag tgatactatc ttaaaaaaac tcaatgataa
    17221 gagccaatta aaacctcacg aaattataga tgctaaggca caaataaaaa aattagcacc
    17281 tcaagttgat ttatcaaaaa ataaagtctt aaataaggct aaaaaaatca aagcagctcg
    17341 tgcccctaga attggtgatg atattatagt gactagttat ggacagcgag gtaccttaac
    17401 tagtcaatta aaagatggcc gttgggaagc acaagtggga attatcaaaa tgacattaac
    17461 acaagatgaa tttagcctcg ttagagtcca agaagaacag aaagtcaaaa ataaacagat
    17521 taatgtggtt aaaaaggctg atggttctgg accaagagct cgacttgatc ttagaggtaa
    17581 aagatacgaa gaagcaatgc aagagttaga tcattttatt gatcaagcat tgcttaacaa
    17641 tatgggacaa gttgatatca ttcatggtat tggtacaggc gttattcgtg agggagtgac
    17701 aaaatatctt cgtcgtaata agcatgttaa gcattttgct tatgccccac aaaatgcagg
    17761 gggatctggt gccacaattg taacgttagg gtaaatgatg gaatcatatg aacactttta
    17821 tgccaaacta tctcaacctt ttagaaaaac cccacagtta ataattcttt taaatgtttt
    17881 actaaaaata atcacaggag tgatgtacat actttatcca tcttttctga tatttacgct
    17941 ttggcaaggg atgacatttc aattatggtt aaggttatta attattcctg ctgttggctt
    18001 tatagctttg tcttacatta ggaaacgctt tgattttcca cgaccgtatg aaaaatggaa
    18061 tattaaacct ttaattgata aggatacaaa gggaaggtca atgcctagca gacatgtttt
    18121 ttcagctacg atgattagta tgtgtttgtt acgatattat gtttactttg gaatagtttg
    18181 tttaatatta tcggctttat tggcaatttg ccgtgtgata gcaggtattc actatcctaa
    18241 ggatgttatt gtaggttacc ttattggctt gatgttaggg ctttgtttat tgatttagcg
    18301 agttcgtagc aaatagtttc aaaaacaact aaattcttgt acaataggct tatcattaag
    18361 atgaaatgga gaaaaaagat ggcattagaa gtaacagatg ctacatttgt agaagaaact
    18421 aaagaaggtt tagtactcat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa
    18481 gcaccaatct tagaacagtt atctcaagaa atcgatgaag atgaactcaa aattttgaaa
    18541 atggatgttg atgaaaatcc ggaaactgct cgtcagtttg gtattatgtc aattccaaca
    18601 ttgatgttta aaaaagacgg agaagtggtt aaacaagttg caggtgttca tactaaagac
    18661 caattgaaag ctattattgc tgaattgagt taactaaaat aaagcccagc gtcacgctga
    18721 gctttatttt atgacctact aacttcaatg gaataaccat gtaaacataa aacgacttgc
    18781 aaaagcaaaa gcaacagtaa tgaggaaaaa tacagtgaca ataaggggtt tctgataagg
    18841 aagtgttgct ctttcttctc gtttttcgat ttcgtctaat aattttccat ttgaaacagc
    18901 taggatttcc ttataaggtt gcacatcata ttttttctta aaacgttcca cacgattagc
    18961 ataagtcata gtaattatcg ataataaaac aaaaatgcca agtcctagcc actctaagaa
    19021 atagactaat ggataacttg aaatcattaa tagtatcatc aatgttacca ttactttggt
    19081 atctcgttta aaattctttt tatcaacctg agtgatggta tatttcattt tctcaatgtc
    19141 tcctttaatg agttggtcta agctcacttg aaaaatttga cttaggagta agaggctatg
    19201 gatgtctggg taagttttgt cattttccca gttagatatg ctctgacggc ttacatagac
    19261 tttctcggct aatttttctt gcgagagcgc ttgttgttta cggtagcgaa taatttgctg
    19321 accaatttcc ataaatatca ccgaaaaact ttacagcggc gtaaaggaat tgtaaacaaa
    19381 aagtgaaccg ttatagttca cttgcgatta agcatttttc tgttttaagt aggtctctag
    19441 cattttcttt tgtggtgttg caaagggata aagagaaaag tcctcaattg ctacccactt
    19501 taggtgagga gcattaggta aatctgttgc tttgaccacc ccctctatga gttctattgt
    19561 ccacttctgg tgactaaaag tgtgcttaat atttggaaag tgattatcag tccattgtgg
    19621 ctttaattga tattctcttt cgaaagtttc attttgggtt tgccagatta tggggttgga
    19681 ttgattgtca tcaaataaat ctaattgttg agaaagaggt gatgtttcga taataggaaa
    19741 tgaccaaaat cctcctagaa gtctcccttt agtatttttc tccagtagat actggccatt
    19801 ttggttacga atgacaaaag cctgaattcg cattggttta ggctttttct ttggattttt
    19861 tatggggtat ttaccataag taccattcaa ataagcagcg ttaaagaaac gaatagggct
    19921 ttcatcaggc ctaggtgtct tagcggattc gatgtctgta cctagatcca taagtgcctg
    19981 gttaaaatca ccgggtctgt cagggtcaat tagtatttcc ataatagctt gaaaaatttt
    20041 acgattttta gggtcaccga tatcataatt aacttcaaac aaacgagcca tgacacgcat
    20101 cacattgcca tcaacagcag gctctggtaa gttgaatgag atgctggcga tagcacctgc
    20161 agtataagga ccaatccctt ttaatgaagc aatatcatca taagtgtgag gaaatatgcc
    20221 accaaaatca accatcactt gctgtgcagc cttttgcata ttacgcaccc gagaataata
    20281 gcctagtccc tcccatgcct ttagtaattg ttcttcagga gcgtctgcca aatcttttat
    20341 ttgaggaaac cactctagaa aacgtttata ataagggatt accgtattaa cttgtgtttg
    20401 ttgcaacatg atttcagaaa cccaaatata atatggatta gtagttcttc gccaagggag
    20461 atcacgtttt tcttggtcat accactctaa aagtgtgcga cgaaaagaag cgattgtctc
    20521 attatcccac atattaatac cataatcttt taattcaatc atgttgttat tgtaacacag
    20581 gagtcttaaa aagagtaaaa aaagatttta ggtatttgcg aaaaagaaaa ggaaatatta
    20641 taataatatt aggtttacct catctaaatg ttgatttaga ataactgaaa ttaacgatag
    20701 aagcagacag gttttaattt ggaggggaca tgttccagaa attaaagaat cttattgatc
    20761 ggtattcgtg gttcgttttt ataatgatga ttcttgtgtt atttcttaac tatatttatc
    20821 catttgatcc ttctttgagc ggactacagt tggaatggct gatcatgacg caagtttttc
    20881 ctggattagg tatcgtatgt gccatggttg ctattatttt taaaaagttt aacctttttg
    20941 ttttggccct aattttatat tttgcacttt ggttaaaact tttccttgct ttttcttttt
    21001 tcacctattt tttaggagtc tgactaagtg ccaattttta aaactcgtga aagaaaatgt
    21061 ttgacaaaac ttagtcaagt agaaaaagtt ccttgctttt aattgactat tagtgtacaa
    21121 taagattctg tgagtatacc tcacttactc actccaaaag tagtgagtca ttagaccaaa
    21181 aggaggaaaa tatcaatggc taaatacgaa attctttata tcattcgtcc aaacattgaa
    21241 gaagaagcta aaaacgcttt ggtagcacgc tttgactcta tcttgactga caacggtgca
    21301 actgttgttg aatcaaaaga ttgggaaaaa cgtcgtcttg catacgaaat caacgatttc
    21361 cgtgaaggac tttaccacat cgttaacctt gaagcgactg acgcagcagc tcttaacgag
    21421 tttgaccgtc tttcaaaaat caatggtgac attcttcgtc acatgatcgt taaacttgac
    21481 gcttaattcc aactaagagg gtagtttatg attaataatg tagtactagt tggtcgtatg
    21541 accaaggatg cagaacttcg ttacacacca agtcaagtag ctgtggctac cttcacactt
    21601 gctgttaacc gtacctttaa aagccaaaat ggtgaacgcg aggcagattt cattaactgt
    21661 gtgatctggc gtcaaccggc tgaaaattta gcgaactggg ctaaaaaagg tgctttgatc
    21721 ggagttacgg gtcgtattca gacacgtaac tacgaaaacc aacaaggaca acgtgtctat
    21781 gtaacagaag ttgttgcaga taatttccaa atgttggaaa gtcgtgctac acgtgaaggt
    21841 ggctcaactg gctcatttaa tggtggtttt aacaataaca cttcatcatc aaacagttac
    21901 tcagcgcctg cacaacaaac gcctaacttt ggaagagatg atagcccatt tgggaactca
    21961 aacccgatgg atatctcaga tgacgatctt ccattctagt cagaatggat tgaacgaata
    22021 cgaaattatt tgagttcggg ctaaaaattt agaacttaga atttagatca actccctagg
    22081 aaatcaagat ttcttgccag ttttctaaaa ttcagtcgtt ttttaagagc ccttaacatc
    22141 ataatttata aaggagaaaa tacatggctc aacaacgtcg tggcggattc aaacgccgta
    22201 aaaaagttga cttcatcgca gctaacaaaa ttgaatatgt tgattacaaa gatactgagc
    22261 ttcttagccg tttcgtttca gaacgtggaa aaattcttcc tcgtcgtgta acaggaactt
    22321 cagctaaaaa ccaacgtaaa gtaacaacag caatcaaacg tgctcgcgtt atggctctta
    22381 tgccttacgt aaacgaagac taataaacaa acagtccatt tcggactgtt ttttagttga
    22441 ctaggactag tctaggcgta taggtgagtt ttttctaaaa gagagaatga tagtaaacga
    22501 aaatccttgc gtagacagca aggatgaaat gattgttatt tgttaacagg tgacatagtg
    22561 ttttgaatgt tgtatttgcg ttgtaggtaa tagcgtaaag caagggaaac accaccaata
    22621 atgagcaagg caagaggagg caactgtggg ttaagagagg ttggtaaaaa ggcagttgca
    22681 gagtacaagg caatccaaat caacatggct aatgataagg ctgcgatgat tttgaaccaa
    22741 cttggacgaa ggctcttatc ttttccgaga tgacggtaaa taaagtaata agtagcgtac
    22801 atggatgctc ctccaccaaa accaagtgcc agtaaggaaa tcaatcctgt aactgtagcg
    22861 tttgtgttga agaaggtcat gatgccattt aaaagggcaa caattccgat gaatagcaaa
    22921 gaggtatcta gccacatcaa ccaaggattg gtgtttttgt cagtttctgc tgctttttga
    22981 ctagggtctt ggctaaaaga agctgcccaa gcagtcggag tgcctaatag atttcgagcg
    23041 gtgactcctt ttttctggtt ttcgagaata gctggaatgg cttcttcgag aatcagctta
    23101 atgtcctcat cagacttgcc gtcttggatt aatttgttcg tagcggtgtg gataaattct
    23161 tgattttttt tggtaagttc ttgtaattcc atgggaatcc cttctttata tgggttagtt
    23221 aaagtaagtc aatgatatta gttagtgtca aatgagactt tggagccagt cgtctgacac
    23281 agagttttgt caggtcttaa ccgcattctg cagcttactc cactctagaa ccattttttt
    23341 ctaataaagt aaatcacaac aaaggaacta aggagcatag caatcaaggt gatataccaa
    23401 aaagcatgtt ctaggccatt tagtggtaac cagttgtttt ggaaattcat accataggcg
    23461 gagaaaatca cagttggtat atctaaagcc atggtcatca aggccagtgt tttcataatg
    23521 gtgttctggt tattgttgat aatagaagca gtggtttcgg tcatggcatt caagacattt
    23581 tcataaatgc cagccatctc aatcgcctgt tgggtttcaa tcaaggtatc ttctagcaaa
    23641 tcctcgtcct caatgtattt cttgagagag cttgttgagc tggataattt cttgacgatg
    23701 cgttcgttga atttcaagga agcctttaag tagacaatgg atttttcaag ttccatcatg
    23761 tcgataagtt cttcatttcg agtagctgct tcaagctgag cttccaaacg ttcgctttgg
    23821 cgatcaatgg tcctcaaggc agtcagaaag agctcggcgt tgcgatatag aatctgaaaa
    23881 acaaaacgtg tcttcatgaa ggtatagaaa tttttgaccc ggcggttgtg aaaatgatcg
    23941 aaaagggtca tgtcatgcag acaagttgtg ataacagcat tttccgttac aataatgcct
    24001 aaaggcatag taatatagta acttttattg ttacgttctt cgtatatcgg gacgtctacg
    24061 ataattaggg tataatcatc ttctacggca atacgtgagg tttcttccac gtccaaaggg
    24121 gcgcgcaagt cagaaatatc aatgttaaat tgatcggcga tcttcataga ctcttcttgg
    24181 gaagggttaa ccagtttaat ccaagctcct ggctcgaatg tttctatttc tttgaattca
    24241 attgccgatg aaagaaacat ttgtttcatg acaagccctc ctttttgatg attaactggt
    24301 agagattgac atcaaacctt gataataaag tcttctcaag gattttctga aaaattctca
    24361 atacttatct attataccaa aattcgcaaa gtttggggca ataggttatc agaaattttt
    24421 gttataatat aagaaagctc gatgaggagg gtgcctttag gcacattcaa gatgcaaaat
    24481 aaaataataa ttcatggggc aagagcccac aatttaaaaa atattgacgt ggaaattcca
    24541 cgagacaaat tagttgtcgt gacagggtta tcagggtcag gaaaatctag tctagccttt
    24601 gatactattt atgcggaagg gcaacgtcgt tacgtagaaa gtttatcagc ttatgctaga
    24661 cagttcttgg gtaatatgga aaaaccagat gtggattcca ttgacggtct tagccctgct
    24721 atttccattg accaaaaaac caccagtaag aaccctcgct caacggttgg tacggttacg
    24781 gaaatcaatg attatttacg tctactatat gcgcgtgtgg gcacacctta ctgtatcaat
    24841 gggcatggtg ctatcacggc gtcttctgca gaacaaattg tagagcaggt cttagccctc
    24901 cctgaacgga cacgcatgca gattttagct cctgttgttc gtcggaagaa ggggcaacac
    24961 aaaacagttt ttgagaaaat tcaaaaagac ggctatgtcc gtgtgcgcgt tgacggggat
    25021 atttttgacg tgacagaagt gccagagttg tccaaaagta agatgcacaa cattgaggtg
    25081 gttattgacc gtctggttaa taaggatggt attcgtagcc gtttatttga ttcggttgaa
    25141 gcagctttaa ggctgggaga tggctacctt atgattgaca ctatggatgg caatgaactg
    25201 ctcttttctg agcattattc ctgtcctgtc tgtggattta cggttcctga attagaacca
    25261 agactcttct cttttaatgc gccgttcggc tcttgtccga cctgtgatgg gctaggcatt
    25321 aagttggaag tggatttgga cttggttgtt cctgacccaa gtaagtcttt gagagaggga
    25381 gctttggcgc cttggaatcc tatttcctcc aattattacc caaccatgct tgagcaagct
    25441 atggcaagtt ttggggtgga tatggataca ccttttgagg ccttgactga ggaagaaaga
    25501 gatttagtgc tttatggttc aggtgataga gaatttcatt ttcactatgt gaatgatttt
    25561 ggtggtgagc gtaacattga cattcctttt gaaggtgttg taactaatgt taatcgccgt
    25621 tatcacgaaa ctaatagtga ttatacgcgc aatgtgatgc gtggttatat gaacgaattg
    25681 acctgtgcga cttgtcatgg ttaccgtttg aatgaccaag ctttgtgtgt gcatgtgggt
    25741 ggcgaagaag gacctcatat tggtcaaatt tcagaattat cgattgccga ccacttgcag
    25801 ttattggaag aattggaact cacagaaaat gaaagtacca ttgctaaacc gattgtcaaa
    25861 gaaatccatg accgtctgac attcttaaat aatgtgggac tgaattatct gaccttgtca
    25921 cgggctgctg ggactttatc aggtggtgaa agtcaacgaa tcaggttagc aacacaaatt
    25981 ggttctaacc tatcaggggt gctctatatc ttggatgagc cttctattgg attgcatcaa
    26041 agagacaatg accgtttgat cgagagcctg aaaaaaatgc gtgatttggg taatacgtta
    26101 attgtggtag aacacgatga agacaccatg atgcaggcag actggctgat tgatgtggga
    26161 ccgggggcag gtgagttcgg tggagaaatt actgcctctg gaacgccgaa acaagtggct
    26221 aagaataaaa aatccatcac gggtcaatat ttgtctggta aaaaattcat tccagtgcct
    26281 ttagagcgcc gttctggtaa tggccgattc attgaaataa aaggagcagc gcagaataat
    26341 cttcaaagcc tcgacgtgag attcccactg ggtaaattta ttgcggtcac aggggtatca
    26401 ggctcaggga aatcaacctt ggttaatagt attttgaaaa aggctgtcgc ccaaaaatta
    26461 aaccgtaatg ctgataagcc tggtaaatat cactctattt ctggtattga acatattgaa
    26521 cgcttgattg acattgacca aagtccgatt ggaaggacgc cacggtcaaa tccagccacc
    26581 tatacgggtg tctttgatga tattcgagac ttgtttgccc aaaccaacga agctaagatt
    26641 cgtggttaca aaaaaggccg tttctctttt aatgtcaaag gtgggcgttg tgaggcttgt
    26701 tcaggtgatg ggattatcaa aatcgaaatg cactttttgc cagatgttta tgtgccttgt
    26761 gaggtttgcc acggcagacg gtataattct gagacgcttg aggtgcatta caaaggaaaa
    26821 aatatcgcag aagtccttga tatgactgtc gatgatgcct tggtattttt ctctgctatt
    26881 cctaaaatcg ctcgaaaaat tcaaacgatt aaggatgttg gacttggtta tgtgacctta
    26941 ggtcaaccag ctaccaccct ctctggggga gaagctcaac ggatgaagtt ggctagtgaa
    27001 ttgcacaaac gctcgacagg taagagcttg tatatcctag atgagccaac gactggttta
    27061 cacacagatg atattgcaag gctattaaaa gttttggaac gctttgtaga cgatggtaat
    27121 acggttcttg tgattgagca taatttggac gttatcaaat ctgctgacca tattattgac
    27181 ttaggaccag aaggtggtga cggaggtggt cagattgttg ccacggggac accagaagag
    27241 gtagctcaag ttaaagaaag ctatactggt cattatttga aagtaaaact acaacaatag
    27301 gattaggagt tcgtttgagc tccttttaat cttttaaatg ctctcaaatc atggtaaact
    27361 taaagtagtt ttttcatgct acaatattct caaaagttac caaaggagtt cgcgatgtca
    27421 ggatttttag aacaacgatt aggtcactgc ctaaggcaga tggcagagaa ggggctagag
    27481 gctcttctag tcacccattt aaccaatagt tattacttga caggtttttc tggaactgca
    27541 gcaactgttt tgataacggc caaacgtcgt gttttgatca cagattcacg ttataccttg
    27601 cttgctaaag ctagtgttga gggatttgat attatcgaaa gccgcacgcc gcttaaggtt
    27661 gtggcagaat tgttagaggc tgatcaaata gattgccttg gttttgagga ccaggtatcg
    27721 ttttcttttt accaggccat gcaagcagaa ctgtcaggaa taaccttgct tgctcagtca
    27781 ggttttgtgg agcatttacg tcttattaag gacgcctctg aaatcgatac cattgctaaa
    27841 gcgtgctcga tctcagacaa agcatttgaa gatgctcttg attttattaa accagggaca
    27901 accactgaac gtgacctggc taatttttta gattttcgta tgcgtcagta tggtgccagc
    27961 ggcacatcat ttgatatcat tgtagcttca ggctatctct ctgccatgcc tcatggacgc
    28021 gccagtgaca aggttatcca gaataaagag agcttgacca tggactttgg gtgttactac
    28081 aatcactatg ttagtgatat gacgaggacc attcatattg gccaagttac tgatgaagaa
    28141 cgtgagattt atgctcttgt tcttgctgct aataaggctt taattgctaa agctagcgct
    28201 ggcatgactt atagtgactt tgacggtatt ccgcgccaac tcatcactga ggcgggttat
    28261 ggcagtcgct tcacacatgg cattggtcat ggcatcgggc ttgacatcca tgagaatcca
    28321 ttttttggga aatctgagca acttctccaa gctggaatgg tggtaacaga tgagccaggt
    28381 atctatttgg ataacaaata tggtgtccgt attgaagatg acttggttat cacaaaaact
    28441 ggttgtcaag tcttgacctt ggcacccaaa gaattaattg tattgtaaaa gaatggttca
    28501 ggaaaggatt aggggagaag caatgacaaa tcgtttatca tggcaagact attttatggc
    28561 caatgcagag ctgatttcca agcgctctac ctgtgatcgc gcctttgtgg gagctgtttt
    28621 ggtaaaggat aaccgcatta ttgccacagg ttacaatggc ggagtttctg ctacggataa
    28681 ctgcaacgaa gcgggtcatt atatggaaga cggacattgt attcgcactg ttcatgctga
    28741 aatgaatgct ttgattcaat gtgcgaaaga aggaatttca acggacggaa ctgaaattta
    28801 cgtgactcat tttccttgta ttaactgcac taaggcgctt ttgcaggcgg ggattacaaa
    28861 gattacctat aaagcacatt accgtccgca cccctttgcc attgaactga tggagaaaaa
    28921 aggggttgcc tatgtgcaac atgatgtgcc tcaaattgtt ttaggaggcg ataaggaaca
    28981 atagaaagtg tacctaaaag gacggtcata aaagatttga gccaaggcca cttttgtggt
    29041 aaaatgaagt gataaatatt ttagtaagag gtaataataa tgattgaagc aagtaagctt
    29101 aaagcaggta tgacatttga agcagaagga aaattaatcc gtgtccttga agctagccac
    29161 cacaaaccag gtaaaggaaa cactatcatg cgtatgaaac tacgtgatgt gcgtacaggt
    29221 tctacttttg acacaactta ccgcccagat gaaaaatttg agcaagccat cattgaaact
    29281 gtcccagcac aatacctata caaaatggat gacactgctt acttcatgaa cactgacact
    29341 tatgatcagt acgaaattcc agttgctaac gttgagcaag aattgcttta cattcttgaa
    29401 aactcagacg tgaaaatcca attttatgga agtgaagtga ttggggtaac ggttccaaca
    29461 actgttgaat tgaccgttgc ggaaacacaa ccatctatta aaggagcgac agtgacgggt
    29521 tcagggaaac ctgcaactct tgagacagga cttgttgtta acgttccaga ctttatcgaa
    29581 gctggccaaa aactaatcat taacactgca gaaggtactt acgtttctcg tgcttaatcc
    29641 tttgtcaaaa cagattagtc taaaaaagag aaaggaaatg ctatgacaac tgaatatatc
    29701 ggtgaaatcg tcatttcacc acgagtgctt gaggttatta cggggattgc tacgacacaa
    29761 gttgagggcg tccactcact ccataacaag aaaatggcag atagctttaa caaagcaagt
    29821 cttggtaaag gggtttatct ccagacagaa gaagatggaa gtgttacagc agatatttat
    29881 gtttacttgc aatatggagt caaggtcccg actgtatcta tgaatattca aaaaacagtc
    29941 aaatctgctg tgtacgatat ggcagaagtg cctatttctg cagttaatat ccatgttgaa
    30001 ggtattgttg cggaaaagac accaaaacca gatttgaagt cactttttga tgaggatttc
    30061 ttggatgact aacagctttc aaaattcaag aagagatttg cgtgaacgtg cctttcaggc
    30121 tttatttaac atagagatgg gagctgagtt attggcagct tctcagtttg cctatggtta
    30181 tgataaagta acaggggagg acgctcaagt attggagctg ccgatttttt tattaagtct
    30241 tgtgacgggt gtcaataatc ataaagaaga gttggataac ttgatatcaa ctcatttgaa
    30301 aaaaggttgg tcgttagaac gcttgacact aacagacaaa acgttattac gactaggtct
    30361 ttttgaaatc aagtattttg acgaaacacc agatcgtgtt gcactaaacg aaatcattga
    30421 agtagctaaa aaatattctg atgaaacctc tgctaaattt attaatggct tacttagcca
    30481 atatgtctcg ggagctcctt cagcaaataa atcataataa gtcggagcaa tcttaggatt
    30541 gtatccgatt ttttcaattt atgtacgaat attaaaagac aaacaagcat actctcgcat
    30601 ctagaaagag taagcttgtt tgtcttttag agtaattagt gattggttat gttttgttta
    30661 aatacttgct cctggaagta gcgtaatcgg taaaatatag tctttactgg ttttttcttt
    30721 tttaattttt ttgatgagta tttcgacact caatttagca atctcatcaa taggttgacg
    30781 aatggtcgct aattgaggaa catattgctg gataaatgtc gttccatcat aacctatgac
    30841 tttcatatcc tctggaatag taatgtgaag ttgtttggct actttcataa tgaggatagc
    30901 agttaaatca tcagaaacga aaaggccatc aggttttcgg gttgccaaaa tggatttaat
    30961 ttccatttcg cgtctaacag gagataggtt atttggtaat ttgatgattt ctgcacttcg
    31021 tttgagctgg tagttaaacc ctagctggcg caaccctgtg ggcgaatcag aattgtcatt
    31081 acctgtaatc atgacaatgt tttgacaacc gtgtttttgc aaagtttgtg cggctaattt
    31141 accaccttca aaattatctg aagaaataac cgggatattt ggcgctagat tacggtcaaa
    31201 agctacaata ggagcttcga cacgctcata atcctcaatt cccaaattat gactggaaga
    31261 aataatgccg tccacttgat tggccgcaag catttctaaa tattcgcgtt ctttgacggg
    31321 attatgttca ctattgcaaa taatagtttt gtagccctgt ttaaacaatt caatttccaa
    31381 atgttcaatt aattcagcgt aaaagatatt gctaatgttg gggaagataa gcccaatgag
    31441 ttgggttgat ttaccttgca aacttctagc gagattgtta ggcttgtagc ccaattcacg
    31501 catggcctta ttcaccttat tcactgtttt ttgggaaagg tagccttttt tgttgattac
    31561 tcgcgaaaca gttgttggac tgacacccgc caaggctgcc acgtctgtta attttgcgac
    31621 cacttgccta atacctcatt tcataataat gtccaaaagc ttgtccttct actacttgga
    31681 tacctgtttg tccgtgggtt gggaaaaccc gactagttag gactttttgc ccttggttaa
    31741 taaagatttc aagaatggaa ttgtccacat agacattaag tgtaacatgg ccttgtggga
    31801 tttggcaaga gcgcaccgta ccatagtctt gggcatattg aacccctgcc cgacttcggt
    31861 caatgcttaa ctgtcctttt gttgtatcca ctttcaatct taggccattc cctttttggt
    31921 cggcaaatag gagcaggtca agcttttttt ggcctggaat cgtcaattcc aattcataac
    31981 agttagaact gtctatttta ttatgaaata attctgctgg ccctcgaaga ttttgtaggg
    32041 ctgaaacagg tgtttgatag agaattccgt ctttaatcct taattctttc actaaactaa
    32101 gagctccttg atagtcataa cgatctgtcg gataatcaat atctggtaac ccaatccaag
    32161 acacggctag aaccctgcca tctggactac taaaggcttg agtggcataa gcttcaaaac
    32221 caaagtcaag attttgaagg gcccctccac ccagcaattg gccagtttct ggattgaagc
    32281 tttcaaaaat tttataggta ttggggtaga tattttgata atctaaatca gctttagcca
    32341 gtccttgtgg gctgaaaatc aaaacaggct tgtcatcgac aaacacaagg ttggggcatt
    32401 caatcatgta ttccgtacca gaatcgtcaa agtccaaatc ggctataaat cgccagttgt
    32461 ccacatgatt gtccacagct ttgtaaagtt tgatttttcc tttgccatct aaaccttggg
    32521 cgccaataat agcatagaat tgaccttgat aagaaaaaag ctgaggatcc cgaaaatgtt
    32581 ctgtaacatc atcgggctgt tcaatcaaaa cctgtggtat tttggaaata tttccttgtt
    32641 tatccatcca tgcgccaacc tgtaatggtg ttctgaccca attggcatcg cgaacattac
    32701 cagtgtaaaa gaggaagagc ttgtcatcaa tagcatatgc agaacctgag taagccccat
    32761 gactatcgtg agcgtggtct ggcagaaggc ggctccttgt ttccgtaaaa tggacgaggt
    32821 ctgtggatgt catgtgtacc cattgtttca gaccatgcgc agcgccataa ggccagtttt
    32881 gataaaaaag atggtagcga ccgttgaaat aagaaaaccc attggggtca ttgagtaatc
    32941 ctgtcttagg ttcgacatga aattggctgt gccatgggga ttgggccatt ttttcagtaa
    33001 tagcttggta gtcttttgag ctccactctt tgtaagggcg gtagcgaata gcttgtggta
    33061 gatccatcaa aatctccttg ttttatagtc gtcttcaaga atatactaaa cgttttctgt
    33121 ttaaaaatca agaatttaaa gcatataaaa taaaaatatg ttaaacgctt gacataaaaa
    33181 atattagtga taaaatgata gtcaagaagt gaagcggatt cactagcgtt ggtcctgcac
    33241 attcttagcc acaaagctgg cagaatggat gagggactaa caccaaatga aaaaggagac
    33301 ttttaggcat ggataatcgt cagattgcag ctgaagtgat tgaggcttta ggtggccgag
    33361 aaaatgtgag aagtgttgcc cactgtgcaa ctcgccttcg cgtgatggtt tatgatgaag
    33421 gaaagattga taaggaaaaa gcagaagcta ttgacaaggt taaaggagct ttctttaact
    33481 ctggtcaata tcagatgatt tttggaactg gtaccgttaa taacatttat gacgaagttg
    33541 ttgctcttgg tttacccacg tcatcaacca gtgagcaaaa ggcagaagca ggcaaacatg
    33601 gcaatatctt ccaacgggcg attcgtacgt ttggagatgt ctttgttccc attattccag
    33661 ctattgtagc aacgggtctc tttatggggg ttcgtggttt ggtgacccag ccagctatta
    33721 tggatttatt tggggtgcat gagtacgggg aaaattttct catgtacact cgtattctaa
    33781 cggatacagc ctttgtctac ttgccagctt tggtggcttg gtcagccttt agggtctttg
    33841 ggggtaatcc tattatcggt attgttttag gattgatgct ggtttccaat gagttgccta
    33901 atgcttgggt agttgcctct ggtggagatg ttaagccgct aaccttcttt ggatttgttc
    33961 ctgttgttgg ttatcaaggt accgttttac ccgccttctt tgttggtctg gtaggagcta
    34021 agttggagaa atggttgcac aaaaaggttc cagaagcttt ggacttattg gtcacaccgt
    34081 ttttaacgtt tgctattatg agtaccttgg gactatttgt gattggacca gttttccatt
    34141 ctcttgaaaa ccttgttctg gctgggacac aggccgtctt gcatttgccg tttggcattg
    34201 caggcttgat tgttggggga atccaacaat taatcgtagt gactggtatt caccatatct
    34261 ttaacttcct agaagcgcag ctgattgcca ataccggaaa agatcctttc aatgcttacc
    34321 taacagcagc aacagctgct caagctggag ctaccttagc tgttgctgtt aaaaccaaat
    34381 caacaaaact aaaaggtctg gcctttccat caaccttgtc agctctttta gggattactg
    34441 aaccagctat ttttggggtc aacctccgtt atccaaaagt ctttgtttca ggtcttattg
    34501 gtggtgcctt aggtggttgg gtcgctgggc tctttggcat tgcaggaact ggttttggga
    34561 ttacggtctt accaggaact ctcctttact tgaatggcca attattacaa taccttgtga
    34621 ctatgcttgt cggtcttggg gtagcctttg caattgctta tacttggggt tatcaagata
    34681 gagaaaccct tccgttacca gctgtcgaag ttgatcaaac ggctgatcag ccagccttag
    34741 cagaggaaac tttatatagt cctttgaatg gaacagttgt agacttatct gcggtttcag
    34801 accctgtttt ttcatcaggt gctatgggtc aaggcttagc aattaagcca gaagataata
    34861 ccctatactc accagttgat ggtaaagttg aaattgtctt tgaaacaggt catgcctatg
    34921 ctataacgtc aagtcaagga gcagaagtgt tacttcatat tggtattgat accgtgtcga
    34981 tggcaggaga tggctttgaa tctcttgtag cagtaggtca ggcggttaaa aaaggtgatc
    35041 ttcttggaca ctttgatcct agcaagattg cagaagctgg actagatgac accaccatga
    35101 tgattgtgac caatagcgct gactatcaaa gcgtggacat tcttgctcaa ggacatgttt
    35161 tgattggtga tcaagtggca cttatcaaat aaggacaaaa gagctaacta agcagctctt
    35221 ttgtcctgcc atggatggca ggttggcaaa aaaatgagaa aagcctaaaa accttaaatt
    35281 tgtgttattt tacctatact ttgtaccttg ttttttttaa taaagtgttg ttatacttaa
    35341 ggcgaactat aggaatgcgc ttacatggat ggtatatcaa ctgggaagcc atgacttagt
    35401 accaaaaata aggagtgtcc aaatggataa acatttgttg gtaaaaagaa cactagggtg
    35461 tgtttgtgct gcaacgttga tgggagctgc cttagcgacc caccatgatt cactcaatac
    35521 tgtaaaagcg gaggagaaga ctgttcaggt tcagaaagga ttaccttcta tcgatagctt
    35581 gcattatctg tcagagaata gcaaaaaaga atttaaagaa gaactctcaa aagcggggca
    35641 agaatctcaa aaggtcaaag agatattagc aaaagctcag caggcagata aacaagctca
    35701 agaacttgcc aaaatgaaaa ttcctgagaa aataccgatg aaaccgttac atggtcctct
    35761 ctacggtggt tactttagaa cttggcatga caaaacatca gatccaacag aaaaagacaa
    35821 agttaactcg atgggagagc ttcctaaaga agtagatcta gcctttattt tccacgattg
    35881 gacaaaagat tatagccttt tttggaaaga attggccacc aaacatgtgc caaagttaaa
    35941 caagcaaggg acacgtgtca ttcgtaccat tccatggcgt ttcctagctg ggggtgataa
    36001 cagtggtatt gcagaagata ccagtaaata cccaaataca ccagagggaa ataaagcttt
    36061 agccaaagct attgttgatg aatatgttta taaatacaac cttgatggct tagatgtgga
    36121 tgttgaacat gatagtattc caaaagttga caaaaaagaa gatacagcag gcgtagaacg
    36181 ctctattcaa gtgtttgaag aaattgggaa attaattgga ccaaaaggtg ttgataaatc
    36241 gcggttattt attatggata gcacctacat ggctgataaa aacccattga ttgagcgagg
    36301 agctccttat attaatttat tactggtaca ggtctatggt tcacaaggag agaaaggtgg
    36361 ttgggagcct gtttctaatc gacctgaaaa aacaatggaa gaacgatggc aaggttatag
    36421 caagtatatt cgtcctgaac aatacatgat tggtttttct ttctatgagg aaaatgctca
    36481 agaagggaat ctttggtatg atattaattc tcgcaaggac gaggacaaag caaatggaat
    36541 taacactgac ataactggaa cgcgtgccga acggtatgca aggtggcaac ctaagacagg
    36601 tggggttaag ggaggtatct tctcctacgc tattgaccga gatggtgtag ctcatcaacc
    36661 taaaaaatat gctaaacaga aagagtttaa ggacgcaact gataacatct tccactcaga
    36721 ttatagtgtc tccaaggcat taaagacagt tatgctaaaa gataagtcgt atgatctgat
    36781 tgatgagaaa gatttcccag ataaggcttt gcgagaagct gtgatggcgc aggttggaac
    36841 cagaaaaggt gatttggaac gtttcaatgg cacattacga ttggataatc cagcgattca
    36901 aagtttagaa ggtctaaata aatttaaaaa attagctcaa ttagacttga ttggcttatc
    36961 tcgcattaca aagctcgacc gttctgtttt acccgctaat atgaagccag gcaaagatac
    37021 cttggaaaca gttcttgaaa cctataaaaa ggataacaaa gaagaacctg ctactatccc
    37081 accagtatct ttgaaggttt ctggtttaac tggtctgaaa gaattagatt tgtcaggttt
    37141 tgaccgtgaa accttggctg gtcttgatgc cgctactcta acgtctttag aaaaagttga
    37201 tatttctggc aacaaacttg atttggctcc aggaacagaa aatcgacaaa tttttgatac
    37261 tatgctatca actatcagca atcatgttgg aagcaatgaa caaacagtga aatttgacaa
    37321 gcaaaaacca actgggcatt acccagatac ctatgggaaa actagtctgc gcttaccagt
    37381 ggcaaatgaa aaagttgatt tgcaaagcca gcttttgttt gggactgtga caaatcaagg
    37441 aaccctaatc aatagcgaag cagactataa ggcttaccaa aatcataaaa ttgctggacg
    37501 tagctttgtt gattcaaact atcattacaa taactttaaa gtttcttatg agaactatac
    37561 cgttaaagta actgattcca cattgggaac cactactgac aaaacgctag caactgataa
    37621 agaagagacc tataaggttg acttctttag cccagcagat aagacaaaag ctgttcatac
    37681 tgctaaagtg attgttggtg acgaaaaaac catgatggtt aatttggcag aaggcgcaac
    37741 agttattgga ggaagtgctg atcctgtaaa tgcaagaaag gtatttgatg ggcaactggg
    37801 cagtgagact gataatatct ctttaggatg ggattctaag caaagtatta tatttaaatt
    37861 gaaagaagat ggattaataa agcattggcg tttcttcaat gattcagccc gaaatcctga
    37921 g
//
LOCUS       DAUGQX010000016        37762 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUGQX010000016 DAUGQX010000000
VERSION     DAUGQX010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37762
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.016"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            73..864
                     /locus_tag="VIA51_000723"
     CDS             73..864
                     /locus_tag="VIA51_000723"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEQ8682679.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            941..1375
                     /locus_tag="VIA51_000724"
     CDS             941..1375
                     /locus_tag="VIA51_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8682680.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            1376..2350
                     /locus_tag="VIA51_000725"
     CDS             1376..2350
                     /locus_tag="VIA51_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEQ8682681.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVRI"
     gene            2411..2635
                     /locus_tag="VIA51_000726"
     CDS             2411..2635
                     /locus_tag="VIA51_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8682682.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            2837..3808
                     /gene="fabK"
                     /locus_tag="VIA51_000727"
     CDS             2837..3808
                     /gene="fabK"
                     /locus_tag="VIA51_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEQ8682683.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            3833..4771
                     /gene="fabD"
                     /locus_tag="VIA51_000728"
     CDS             3833..4771
                     /gene="fabD"
                     /locus_tag="VIA51_000728"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEQ8682684.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            4761..5495
                     /gene="fabG"
                     /locus_tag="VIA51_000729"
     CDS             4761..5495
                     /gene="fabG"
                     /locus_tag="VIA51_000729"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEQ8682685.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            5510..6742
                     /gene="fabF"
                     /locus_tag="VIA51_000730"
     CDS             5510..6742
                     /gene="fabF"
                     /locus_tag="VIA51_000730"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEQ8682686.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMVDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            6744..7244
                     /locus_tag="VIA51_000731"
     CDS             6744..7244
                     /locus_tag="VIA51_000731"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEQ8682687.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            7241..7663
                     /gene="fabZ"
                     /locus_tag="VIA51_000732"
     CDS             7241..7663
                     /gene="fabZ"
                     /locus_tag="VIA51_000732"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEQ8682688.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            7695..9059
                     /locus_tag="VIA51_000733"
     CDS             7695..9059
                     /locus_tag="VIA51_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEQ8682689.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            9068..9934
                     /locus_tag="VIA51_000734"
     CDS             9068..9934
                     /locus_tag="VIA51_000734"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEQ8682690.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKEQKIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            9931..10701
                     /locus_tag="VIA51_000735"
     CDS             9931..10701
                     /locus_tag="VIA51_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEQ8682691.1"
                     /translation="MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYKMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(10923..12200)
                     /gene="serS"
                     /locus_tag="VIA51_000736"
     CDS             complement(10923..12200)
                     /gene="serS"
                     /locus_tag="VIA51_000736"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEQ8682692.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(12592..12951)
                     /locus_tag="VIA51_000737"
     CDS             complement(12592..12951)
                     /locus_tag="VIA51_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEQ8682693.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            complement(13065..13976)
                     /locus_tag="VIA51_000738"
     CDS             complement(13065..13976)
                     /locus_tag="VIA51_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8682694.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTIRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            complement(13993..14802)
                     /locus_tag="VIA51_000739"
     CDS             complement(13993..14802)
                     /locus_tag="VIA51_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEQ8682695.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            complement(14891..15883)
                     /gene="manX"
                     /locus_tag="VIA51_000740"
     CDS             complement(14891..15883)
                     /gene="manX"
                     /locus_tag="VIA51_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEQ8682696.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            complement(16235..17047)
                     /locus_tag="VIA51_000741"
     CDS             complement(16235..17047)
                     /locus_tag="VIA51_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8682697.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALGYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRACFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            17311..18771
                     /locus_tag="VIA51_000742"
     CDS             17311..18771
                     /locus_tag="VIA51_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEQ8682698.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSGVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIIVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            18925..19386
                     /gene="tsaE"
                     /locus_tag="VIA51_000743"
     CDS             18925..19386
                     /gene="tsaE"
                     /locus_tag="VIA51_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEQ8682699.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHGSAKSRY"
     gene            19361..19885
                     /locus_tag="VIA51_000744"
     CDS             19361..19885
                     /locus_tag="VIA51_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8682700.1"
                     /translation="MVQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            19894..21168
                     /locus_tag="VIA51_000745"
     CDS             19894..21168
                     /locus_tag="VIA51_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8682701.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSNKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVNQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGQSASTDQDSTASSHRPA
                     TPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(21279..21635)
                     /locus_tag="VIA51_000746"
     CDS             complement(21279..21635)
                     /locus_tag="VIA51_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ8682702.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(21632..22051)
                     /locus_tag="VIA51_000747"
     CDS             complement(21632..22051)
                     /locus_tag="VIA51_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8682703.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            22123..22848
                     /locus_tag="VIA51_000748"
     CDS             22123..22848
                     /locus_tag="VIA51_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682704.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            22851..23885
                     /locus_tag="VIA51_000749"
     CDS             22851..23885
                     /locus_tag="VIA51_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682705.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNMLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            23949..24740
                     /locus_tag="VIA51_000750"
     CDS             23949..24740
                     /locus_tag="VIA51_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEQ8682706.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            24740..25375
                     /gene="trmB"
                     /locus_tag="VIA51_000751"
     CDS             24740..25375
                     /gene="trmB"
                     /locus_tag="VIA51_000751"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEQ8682707.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            25440..25526
                     /locus_tag="VIA51_000752"
     tRNA            25440..25526
                     /locus_tag="VIA51_000752"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25474..25476,aa:Ser,seq:gga)
     gene            complement(25573..26652)
                     /locus_tag="VIA51_000753"
     CDS             complement(25573..26652)
                     /locus_tag="VIA51_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8682708.1"
                     /translation="MAFYRKLGSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AEIDLNTLTADLLDITVLDYNRRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGAKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADGAIVRSQKP
                     AKEESEKFMEESEYLAFIKVAKSKVKYPSYLTTYIIAVTGLRFAEVQGLTWKDIDFEN
                     GYIDINKTFDYSISQNFGPTKNEQSIRKVPIDKNSLEILRNFKSDYYQDNKLGRVCFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKFDG"
     gene            complement(26769..27320)
                     /locus_tag="VIA51_000754"
     CDS             complement(26769..27320)
                     /locus_tag="VIA51_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682709.1"
                     /translation="MDIAKLKEFAITAAGKAKDGAIKANELRKKASQESKIILPPALN
                     LELGAQTAIRKTIDGKYYIGFYSETPELYEFVSLQFDGSRIIEKTVTKGKTTQKGRSS
                     SVLGGAAIGKVLAPGVGTIIGGMAGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEVKTLKTKLTQAQYVSVNNFFK"
     gene            complement(27331..27714)
                     /locus_tag="VIA51_000755"
     CDS             complement(27331..27714)
                     /locus_tag="VIA51_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEQ8682710.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMIKEELEFLIS"
     gene            complement(27728..28129)
                     /locus_tag="VIA51_000756"
     CDS             complement(27728..28129)
                     /locus_tag="VIA51_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682711.1"
                     /translation="MLFYRYFLSSHRKADKSMFSTFERIKELAKSRGISLGLLEEKLG
                     LSRNSIYTIKNKKPSAERLQLIADYFHVSTDYLLGRTDNPKIAQDGHASVAIDLKKDA
                     EETFFFDGHELNDEDIDLITSILETRIKNRK"
     gene            28404..28559
                     /locus_tag="VIA51_000757"
     CDS             28404..28559
                     /locus_tag="VIA51_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682712.1"
                     /translation="MDEKNPLEQFEEFCKNNSFEYVKGWVDGMQSVLNILSMELSKKN
                     GSTSEVD"
     gene            complement(28540..28953)
                     /locus_tag="VIA51_000758"
     CDS             complement(28540..28953)
                     /locus_tag="VIA51_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682713.1"
                     /translation="MEKFNFWLTIATAVLPAAISAIISFLASRYKNRSDIESLEKKFN
                     HEMTTIEKNHSNDLERLEKQYQHDFEAMEKNHFRELEKMKEAHTLELENIQKQSEAEV
                     NNTVAQGLMTMLGSAMTPALSKYLEENDVFNQPPK"
     gene            29001..29216
                     /locus_tag="VIA51_000759"
     CDS             29001..29216
                     /locus_tag="VIA51_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8682714.1"
                     /translation="MSQQHKKWSALVEQRLKEKGWTRVDLALAAGLRSSGTITDLLTK
                     GKGSVDLKVRVSKILSIREPWELFENE"
     gene            29278..29553
                     /locus_tag="VIA51_000760"
     CDS             29278..29553
                     /locus_tag="VIA51_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEQ8682715.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVMKMINNETEIYPLELNKKQVS
                     KMFGVDPKTFDARFNSHKDFPRIETGGREKYPRDLAIEWYHRNWSIT"
     gene            29550..29720
                     /locus_tag="VIA51_000761"
     CDS             29550..29720
                     /locus_tag="VIA51_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682716.1"
                     /translation="MNKLELFLLATTVILAVIARVQHEVIKKHNSPENKRRIFREVAL
                     ENSKKWSAERYV"
     gene            29713..29916
                     /locus_tag="VIA51_000762"
     CDS             29713..29916
                     /locus_tag="VIA51_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682717.1"
                     /translation="MSKWELQKQLLANATDFESTVEALFELNELGEISDEELLLNLRS
                     SYRKYSEEKLCIIDKLIKLGGAE"
     gene            29913..30299
                     /locus_tag="VIA51_000763"
     CDS             29913..30299
                     /locus_tag="VIA51_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682718.1"
                     /translation="MMTTFEKIIKNLNRIERELVKPEAERRDSLPILSAQLSAIKQDL
                     KLMLWIELPALNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            30445..30648
                     /locus_tag="VIA51_000764"
     CDS             30445..30648
                     /locus_tag="VIA51_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682719.1"
                     /translation="MNYLEYALAYLERELEIIDDEVIEVELPGGDWEFVPNPYYEEGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            30736..31035
                     /locus_tag="VIA51_000765"
     CDS             30736..31035
                     /locus_tag="VIA51_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682720.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            31035..32189
                     /locus_tag="VIA51_000766"
     CDS             31035..32189
                     /locus_tag="VIA51_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEQ8682721.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYED
                     AEIELEKRIDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVLTNKEAAATILEKNGFEDIYKPKELLSM
                     GALEKMVGKKRFEDMMAFILDKPQGKPVLVKNSDKRPALNSLEQAIKEFE"
     gene            32193..32591
                     /locus_tag="VIA51_000767"
     CDS             32193..32591
                     /locus_tag="VIA51_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682722.1"
                     /translation="MKIYKVKVKFRQTCHKKFKGKKYSYFSFEELRVGDLVVVETVYG
                     PSVAKVTEVVDANELFTATSYVISKVDTSLLAGKKELMATALTVKANIDAETAEFAAK
                     YKDAYYLGLFDQYKNQNPELAELLTQLKEL"
     gene            32602..33159
                     /locus_tag="VIA51_000768"
     CDS             32602..33159
                     /locus_tag="VIA51_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEQ8682723.1"
                     /translation="MTPSTTKVVTGKVRLSYAALLEPKAFEGQEAKYSTVILIPKTDK
                     VTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHMFMSVS
                     SKTRPQIIDRYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAKGD
                     YLGGRSSADADFDEWNEEEDEDDIL"
     gene            33202..35124
                     /locus_tag="VIA51_000769"
     CDS             33202..35124
                     /locus_tag="VIA51_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEQ8682724.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPAQWQCTMVLA
                     QELGLPASLEKCALYLKLAQEKDAAGKNLIKYFSVPCKPTKANGGRTRNLPEHDPGKW
                     QMFINYCMQDVVVEMAIAEKLESVPVHDREWDYYVCDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKALTGLDNPNSRAQLLPWLKEHGYSANGLTKADVEQELKKAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGYTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKI
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDRAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYDVVFHVHDEAIIEGSGLIIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            35129..37513
                     /locus_tag="VIA51_000770"
     CDS             35129..37513
                     /locus_tag="VIA51_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8682725.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAFVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLSEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVSDLPEIKDHLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNNFKTKFDPELHARSSHPVVYDPEATCETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGAALKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELNYENKNVKSDGKQAKNWVGFRLKSEF"
BASE COUNT        11519 a         6674 c         8239 g        11330 t
ORIGIN      
        1 gatttgatta tcaaatgatt ttaaagagaa ataatttctt agtcaaataa attatcagaa
       61 aagaggattg ttatgcagtt taaacacatc atctttgatg ttgtagatga tcttgcgaca
      121 ttgactttaa accgtccaga ggtttcaaac ggttttaata ttccaatttg tcaagagatt
      181 ctggtagcat tagcagaagt taaacgcgat acatctgtgc gttttttatt aattaaagcc
      241 gttggaaaag tgttttcagt tggtggtgac ctagttgaaa tgcaagaagc tgttgcaaaa
      301 gataatgtgc agtcgctagt caagattgct gaactggtac aagaaatttc ttttgcaata
      361 aagcatttgc caaaaccagt catcctttgc gccgatggag ctgtagctgg agcggctttt
      421 aatatagctt tagctgttga cttttgtatc gctagtactc aaacaaaatt tatccaagct
      481 tttgtaaatg ttggactagc accggatgcc ggtggtttat ttctattgac tcgtgcagta
      541 ggacttaatc gtgcaactca ccttgtgatg acaggtgaag gaattactgc tgataaaggt
      601 ctcgattatg ggtttgtcta ccgtacggca gaatctgata aactagacaa agtttgtctt
      661 caacttttaa agcgattgag acgtggctct tcaaattctt atgctggaat gaaatcattg
      721 gtctggcaaa gttttttcac aggatgggaa gattatgcta aggcagagct tgctattcaa
      781 gaggagctag ctttcaagga agattttaaa gaaggtgtca tagcttttgg agaaaggcgc
      841 cgaccaaatt ttcaaggtaa gtaagacagc tattgcttgc aaaatacttt gacctttgat
      901 ataatttgat tgtcaaagtt tattgctagg aggtgtttac ttggaatatg acaaaattaa
      961 ccaatactta gttgatattt tcaaccggat tttggttatt gaagaaatga gcttaaagac
     1021 gagtcagttt agtgatgtct ctttaaaaga gatgcacact attgaaatta tcggcaaata
     1081 tgatcaggtg actccaagtg atatcgccag agaattaatg gtaacgttag ggacagtaac
     1141 cactagctta aataaattag aagcaaaagg ttatatcgca agaacgcgat cacgctcaga
     1201 taggcgagtt gtttacctgt cattaacaaa aaggggtcga cttttggacc gcctccatgc
     1261 aaagttccat aaaaatatgg ttggacatgt cattgctgat atgagtgatg aagagatgca
     1321 ggcattggtg cgtggactag ggaatctaca tcaatttttg gaggatttgg tttaaatgat
     1381 tttttctaaa atcagtcagg tagcccacta tgttccacag cagttagtga ctaataatga
     1441 tttagctagc ataatggaca ctagtcatga gtggatcttt tctcgaacag gaatagcaga
     1501 acgccatatt tctagagatg aaatgactag tgacctagct attcaggttg ctgatcagct
     1561 tttaactcag tctgggttaa aagctgatgc tattgatttt attattgttg caactatcag
     1621 ccctgatgcc actatgccat caacagctgc gaaagttcaa gcagctattg cggctacaag
     1681 tgcttttgct tttgatatga ctgctgcttg tagtggcttt gtctttgcct tggctatggc
     1741 agataagctt attgcatcag gtgcctacca aaacggaatg gtaataggtg cagagacttt
     1801 atctaagtta gtaaactggc aggatcgagc gacagccgtt ctttttggag acggagctgg
     1861 tggcgtgcta ctggaagcca gtaaagataa gcatgtttta gcggaaacat tacacacaga
     1921 tggtgcgaga tgtcagagtt tgatttcagg agaaactagt ctttcatctc cttactcaat
     1981 tggcaaaaaa gccatagcga ctattcagat ggatggacgt gccatatttg attttgcgat
     2041 tagggatgtg tcaaaaagca tcctcacact aatggcgcaa tcagatatta caaaagatga
     2101 catagactat tgtttattgc atcaagctaa tcgtcgtata cttgataaaa tagcacgcaa
     2161 gattgatgtt cctcgggaaa aattccttga aaacatgatg cgttatggta atactagtgc
     2221 tgctagtatc ccaatcctct tgtcagaggc tgttcaaaag ggacagatta ggttagatgg
     2281 tacccaaaaa atcttacttt ccggttttgg tggaggtttg acatggggaa gtctaattgt
     2341 tagaatctag ttattcatgt gcctagcaca tttataaaaa caaatttata ttttttaagg
     2401 agaaataaac atggcagtat ttgaaaaagt acaagaaatt attgttgaag aacttggtaa
     2461 ggagacagaa gaagtaacac tagaaactac atttgatgat ttagatgcag attcacttga
     2521 tgttttccaa gttatttcag aaattgaaga tgcttttgat attcaaattg aaacagaaga
     2581 aggattaaat actgttggtg accttgttgc ttacgttgaa gaaaagtcaa aataaggata
     2641 aaagtgacaa gtaacatcag aagtctatga aaagcttact gctgttatgt tcatgttcat
     2701 cactaaaaaa aacaataagt attaatcaaa ccattagggt gggattagac tctttttagg
     2761 atctagctcg ctctttcttc ttactataat agtttgatta tcaaattatt ctccttattt
     2821 tttatagaaa gttattatga aaacacgtat tacagaatta cttaatattg attaccccat
     2881 ttttcaagga ggaatggctt gggttgctga tggtgattta gcaggtgcag tttctaatgc
     2941 tggtggttta ggcattatag gtggtggcaa tgctcccaaa gaagtcgtta aagctaatat
     3001 tgatcgtgtc aaagctatta ctgatagacc ttttggggtt aatatcatgc ttttatctcc
     3061 ttttgctgat gatatcgttg atctggtcat tgaagaaggt gttaaagtag taacaacagg
     3121 cgcaggaaat ccaggaaagt atatggaaag actgcaccag gcgggtataa tcgttgttcc
     3181 tgttgtccca agcgttgcgc tagccaaacg tatggaaaag cttggggtag atgctgttat
     3241 tgctgagggt atggaagctg gaggacatat tggcaagtta acgactatgt ctttagtaag
     3301 acaagttgtt gaagcggttt cgattcctgt cattgcggca ggtggtatag ctgatggtca
     3361 tggtgcagca gcagcattta tgttaggagc agaggctgtt caaattggaa ctcgctttgt
     3421 tgttgctaaa gaatccaatg ctcaccaaaa ttttaaagat aaaatcttag cagcaaaaga
     3481 tattgatacg gtgatttctg cgcaggttgt gggccaccct gtccgttcta ttaaaaataa
     3541 attgacctca gcttacgcta aagcagaaaa agcattttta attggtcaaa aaacagctac
     3601 tgatattgaa gaaatgggag caggatcgct tcgacacgct gttattgaag gcgatgtagt
     3661 caatggatct gttatggctg gccaaattgc agggcttgtg agaaaagaag aaagctgtga
     3721 aacgatttta aaagatattt attatggtgc agctcgtgtt attcaaaatg aagctaagcg
     3781 ctggcaatct gtttcaatag aaaagtagat aaacacatga aggataatga taatgacaaa
     3841 gacagccttt ttatttgccg gtcaaggtgc tcaaaaatta gggatggcaa gggattttta
     3901 tgataacttt gctattgtaa gaaaaacctt tgatcaagct agtcaagtat tgggatacga
     3961 tttgcgccgt ttgattgata gtgacgagtt aaaacttaat caaactagct atacgcaacc
     4021 agctattttg acatcatcaa ttgctattta ccgtgttttg ggcttacatc acgttaaacc
     4081 ggatatggta gctggtcttt ccttaggaga atactcagct ttggtagcat caggggcact
     4141 ctcttttgaa gataccctat ccttagtagc taagagaggc cgcttgatgg aggaagcagc
     4201 accacaagga tctggaaaga tggttgccgt tatgaataca gacgtgcaag tcatcgaaga
     4261 agtctgtcaa atagctgcta aacatggagt ggttgctcca gcaaactata atactcctag
     4321 tcaaattgta attggtggtc agacagatgc tgtgaacgtg gcagttgaac ttttaaagga
     4381 aaggggagtt aagcgtttaa tccctttaaa cgtgtcaggt cctttccaca ctgctttgtt
     4441 agaaccagct agccgcttgt tggctaaaga gttggaaaga tacaacttca gtgacttcaa
     4501 gattcctttg gttggtaata ccgaagctaa tattatggaa aaagaccgta tcccagaact
     4561 attagcccgt caagtcatgg agcctgttcg tttttatgac agtgttgcga ctttagtaga
     4621 aagtggcata acacaattca ttgaggtagg accaggtaag gttttgacag gttttgtgaa
     4681 gaaaattgat aaaaatttac tatgtactag tgttgaaaac atggtaagct tacgtttatt
     4741 tttagataga gaggacattc atggaaatta aaggaaaaaa tatatttatc acaggctcaa
     4801 cgagaggtat cggtttagca atggctcatc aattcgccag tttaggagct aatattgtct
     4861 taaatggtcg ctctgctatc tctgaggagc ttgttgctag ttttactgac tacggcgtta
     4921 cagttgttac catctctggg gatgtttcag aagcatcaga agctaaacgt atggtcaatg
     4981 aagctatcga aagtttaggt tcgattgatg ttttagttaa caatgctggc attactaatg
     5041 ataaattgat gcttaaaatg acggaagagg attttgagcg cgtcttgaaa atcaatttga
     5101 ccggtgcttt taacatgact caatcagtgt taaaaccaat gatcaaggcc cgccaaggag
     5161 caattattaa tgtctctagt gtggttggtt taacaggcaa tattgggcaa gcaaactatg
     5221 ctgcttctaa ggcaggaatg attggtttta ccaagtctgt tgcccgtgaa gttgctgctc
     5281 gtaacatttg cgtgaatgct attgctccag gatttatcga gtccgacatg acaggtgtcc
     5341 ttcctgaaaa aatgcaagag caaatcttaa gtcaaatccc aatgaaacgt attggaaaag
     5401 ctcaagaagt tgctcactta gcaagcttct tggtggaaca agattatatt acgggacaag
     5461 ttatcgctat tgatggcggt atgacaatgc aataaggaga cgtagtgaaa tgacatttaa
     5521 aagagtagtg gtaacaggtt atggtctaac atctccaatc gggcatgatc ctgaaacgtt
     5581 ttggaacaat ctgaaagctg gccaaattgg tattggtcct attactaaat ttgacacgac
     5641 tgattatgca gtcaagaatg ctgctgaaat tcaggatttt ccatttgaca aatactttgt
     5701 gaaaaaagat ttgaaccgtt tcgatagata ttctctttat gctctttacg cagcgaaaga
     5761 ggctattaat catgctgatt taaatattga gatggttgat tccgatcgat ttggcgttat
     5821 tgttgcttca ggtattggtg gaattgcgga gattgaagag caagtgattc gcttacatga
     5881 aaaagggcca aaacgtgtga agccaatgac gttgccaaaa gcgctaccaa atatggctgc
     5941 aggaaatgtc gccatgtctt taaaagctca aggagtatgt aaatcaatta atactgcctg
     6001 cgcttcttca aatgatgcga ttggggatgc ctttcgtgcc attaaatttg ggactcaaga
     6061 tgtgatgata gttggtgggt cagaggcggc cataaccaag tttgccattg ctggcttcca
     6121 aagtttaaca gctctctcaa caactgaaga tccaagcaga agctctattc catttgataa
     6181 agaccgcaat ggttttatca tgggagaagg atcaggaatg cttgttttag aaagcctaga
     6241 acatgcgcaa gaacgcgggg cgacaatctt agcagaaatt gtgggttatg gaaatacctg
     6301 cgatgcctac catatgacat ctccaaatcc tgagggatta ggagctcgta aagccatcca
     6361 cttagcctta caagaagctg gtattgaagc cagtgctatt aattatgtca atgcgcacgg
     6421 aacttcaacc ccagctaatg aaaaaggaga gagtcaagca attgtagccg ttcttggtaa
     6481 ggatgttccg gtgtcttcaa caaaatcgtt tacgggtcac cttcttggag cagcaggcgc
     6541 tattgaagct attgccacta tcgaggctat gcgtcataac tatgttccga tgacggctgg
     6601 gacacaagct ttatcagagg atatcgaagc aaatgtcatc tttggagaag gaaaagaaac
     6661 agctatcaac tatgccattt caaatacttt tggatttggt ggtcataatg ctgtattagc
     6721 tttcaaatgt tgggaggagt aggttgaata ttcaagaaat caaagatttg atggctcagt
     6781 ttgatacctc aagcctacgt gaatttttat tcaaaacaaa tgaaggtgag ctaatcttta
     6841 gtaaaaacga acaacacctc aatgcatcga catcaaatca agaacatgct gtgcctgtac
     6901 cacaggtaca acttgttccg aatccaactg cttcggaagc gtccagtcca gcatcagtta
     6961 aggatgttcc tgtagaggag caaccacaag cagaatcttt tgtagcagaa ggtgatattg
     7021 ttgaaagtcc tttagtcggt gtagcctatc ttgcagctag ccctgacaag ccaccatttg
     7081 tggcagtcgg agatactgta aaaaaaggac aaacccttgt gattatcgaa gccatgaagg
     7141 tgatgaacga agtgccagcg ccatgtgatg gtgtgattac agaaattttg gtatcaaatg
     7201 aagatgtcat tgaatttgga caaggattgg tgcggatcaa atgatggata ttagagaaat
     7261 tcaagcggct ttgcctcatc gctacccaat gttattggtt gatcgtgtgt tagaagtgtc
     7321 agacgaccat atcgttgcca ttaaaaatgt gactattaat gagcctttct ttaacgggca
     7381 ttttcctcac tatcctgtga tgccaggtgt tctgattatg gaagctttgg ctcaaacagc
     7441 tggtgtctta gaattgtcaa aagaagaaaa taaaggcaag ttggtctttt acgctggaat
     7501 ggataaagtg aagttcaaaa aacaagtcgt ccctggtgat caacttgtga tgacagcaac
     7561 ctttatcaag cgtcgcggta ccattgctgt cgttgaagcc agggcagaag ttgatggcaa
     7621 gctagcagca agtggaacat taacctttgc ctgtgggcaa tgagaatgat tgttctgcgg
     7681 aggaagaaac ccttatgttt aaaaaaatct taattgctaa tcgtggtgaa attgcagtgc
     7741 gtatcattcg tgctgcacga gaattaggga tttccacagt tgcagtttat tcggaagcgg
     7801 ataaggaagc tctgcacacg atcttggcgg acgaggctat ctgtattggt cctgcccgtt
     7861 ccaaggaatc ctatcttaat atgaattccg tcttgtcagc agctattgtg acaggagccc
     7921 aagcgattca cccagggttt ggctttttaa gtgaaaactc aaagtttgcg accatgtgtg
     7981 aagagatgaa tattaaattt atcggtccat ccgcatcggt tatggataaa atgggtgata
     8041 aaatcaatgc tcgttctgaa atgattaagg caggagtgcc cgttattcca gggtcagatg
     8101 gtgaagttta taacgctcaa gaagccttag ctattgccaa taagattggt tatcctgtca
     8161 tgctaaaagc atcggcaggt ggtggaggta aagggattcg taaagtggag acagaagcag
     8221 atttggaggc ggctttcaat gctgccagtc aagaagcttt gggagctttc ggaaatggcg
     8281 ccatgtattt ggaaaaagta atttatccag ctagacatat tgaggtgcaa attttaggag
     8341 acgcttacgg taacatcatt cacttgggag aacgggattg ctccttgcaa cggaataatc
     8401 aaaaagtctt ggaagaaagt ccatccattg ctattggcaa taccctcaga cacgaaatgg
     8461 ggcaagcagc ggttagagca gctgaagctg tagcctatga aaatgcggga accattgagt
     8521 ttttgttgga cgaagacagc gagaaattct atttcatgga aatgaatacc cgtatccaag
     8581 ttgagcatcc tgtcaccgaa tttgtgacag gagtggatat tgtcaaagag caaatcaaaa
     8641 ttgcagcagg tcagcctttg gcgattaatc aagaagacat cactatcacg ggacatgcta
     8701 ttgaatgtcg tatcaatgct gaaaatactg cttttaactt tgcaccgagt ccaggaaaga
     8761 ttacagactt gtatatgcca agtggtggtg taggactacg agttgattca gcagtttaca
     8821 atggctatgc cattcctcct tattatgaca gcatgattgc taaaatcatc gttcatggaa
     8881 gcaatcgatt tgacgctttg atgaaaatgc aacgtgcctt agttgaattg gaaattgaag
     8941 gcattatcac caatacagac ttccagctcg atttgatttc agataagcga gtgattgcag
     9001 gagattatga tacctctttc ttgatggaaa cgttcctgcc acattacaat aaagattagg
     9061 agaaaatatg gctttatttc gtaaaaaaga taaatacatc cgtattactc ccaataattc
     9121 cctcaaagga tctgtcagcc ataatgtccc agaagttcca gatgaactct ttgcgaaatg
     9181 cccagcttgt aagcacatga tttataagaa agatttggga ttggcaaaga tttgcccaac
     9241 ctgttcttac aattttagga tttctgccca agagcggctg accttaacag ttgatgaagg
     9301 ctctttccaa gaattattta caagtattga aaccaaggat ccgttacgtt ttccaggtta
     9361 tcaggaaaaa ttacaaaaag ccaaggaaac gacaggtctg catgaagctg ttttgacagg
     9421 gaaagctatg gttaaggagc aaaagattgc tcttgctatt atggattctc actttattat
     9481 ggctagtatg ggaactgttg ttggggaaaa aattacccga ttgtttgaat tggctatcga
     9541 agaaaacctg ccggtggtga tttttacggc ttcaggaggc gcccgtatgc aagagggtat
     9601 catgagcctc atgcaaatgg ccaaggtctc tgcagctgtg aaaagacatt ctaatgcagg
     9661 cctcttttac ctcactattt tgacagatcc aactactggt ggggtaacag ctagttttgc
     9721 catggaaggg gatattattt tggcagaacc tcaatccttg gttggctttg caggtcgtcg
     9781 tgtcattgag accacagttc gtgaaaactt gccagatgat ttccaaaaag cagaattttt
     9841 acaagaccat ggttttgtgg atgctattgt gaaacgaaca gagttgcgag acaagattgc
     9901 ccacttagta gcatttcatg gaggtggcca atgacagatg tatcaagaat tttaaaagaa
     9961 gcgcgtgatc aagggcgttt aacaactttg gattacgcca accttatttt cgatgacttt
    10021 atggaactgc atggcgatcg ccatttttca gatgatggtg ccattgtagg tggcctagct
    10081 tatttggcgg gacaacctgt tacggtcatt ggtattcaaa aaggtaagaa tttacaggat
    10141 aatttggcaa ggaattttgg ccagcccaat ccagaaggtt atcgtaaagc tttgcgcctt
    10201 atgaaacagg cagaaaaatt tggacgacca gttgttacgt ttatcaatac tgcaggagcc
    10261 tatccaggtg tcggtgcgga agaacgagga cagggtgagg ccattgctaa aaatttgatg
    10321 gaaatgagtg atctcaaggt tcccattatc gccatcatta ttggtgaagg aggctctggt
    10381 ggtgcattag ccttagcggt tgccgatcag gtctggatgc ttgaaaatac tatgtatgcg
    10441 gttcttagcc cagaaggctt tgcttctatt ttatggaagg atggttcaag ggcgaccgag
    10501 gccgctgaat tgatgaaaat cacagcgggt gaactctaca aaatgggaat agtagaccgt
    10561 attattccag aacatggtta tttttcaagt gaaatcgttg acatcatcaa agctaacctc
    10621 atcgaacaaa taaccagttt gcaagctaag ccattagacc aattattaga tgagcgctac
    10681 caacgctttc gtaaatatta acaacatcct tttggagtct ccctacgtga agggaggcct
    10741 ttccaaaagg gtttttaact agtcttgtaa ataaggaaat gggtatacta ataagacttt
    10801 tgataaacta gtgtgaagaa aagtgttgtt aaaggggcaa tgtagtgagt ttcaagtgat
    10861 gtggtggctc tttaaaatag taaaccccag aaatcacttt aatgatctct ggggtgaatt
    10921 tattatttag gtgaaatgac ggtttcgcca cccatgtaag ggcggagtac ttcagggatg
    10981 gtaacagaac catcttcatt ttggtagttt tctaaaatgg ctgctacggt acgaccgaca
    11041 gcaagtcctg acccattaag ggtgtggaga agtttgacct taccgtcagc ctcatcacgg
    11101 taacggattt gagcacgacg tgcttggaaa tcttctgtat ttgaacatga tgaaatttca
    11161 cgataggtat tttgagctgg aatccagact tcaaggtcat aggttttagc agctgagaag
    11221 cccatgtctc cagtacaaag ggaaatgacg cgatatggca aaccaagttt ttgaagaata
    11281 ttttcagcat tagcagtcat tttttctagt tcttggtaag attcttctgg tttagcaaat
    11341 ttaaccattt caactttgtg gaattggtgt aggcggataa ggccacgtgt gtcacgaccc
    11401 gcagaacccg cttcagaacg aaaagatggg ctcattgcag taaagtaaat tggcaattct
    11461 ttgccgtcta ggatttcccc acggtaataa ttggtcaaag gcacttcagc agttggaatc
    11521 aggacaaagt tggtatcagc taattcaaag gtgtcctctt tgaattttgg atattgtcct
    11581 gtaccaaaca tggaatcgtg gttaaccatg taaggtgtga tgatttcttg ataaccttct
    11641 ttgatatgtt catccagcat gaagttataa agagcacgct ccaaacgagc accaagattt
    11701 ttatagaata agaaacgagc accagttacc tttgccccac gttcccagtc taaaatatca
    11761 agatcttcgc ctagatccca atgagcctta acttcgaagt caaagtcacg aggcgttccc
    11821 caacggcgaa tttcgacatt gtcttcttcg tcagctccaa cagggacaga atcgtgagga
    11881 gtattaggta aaacagtgat gatgtcagta acttgctggt cgatagctac tagttgattg
    11941 tcaatagttt tgatatctgc agagactttt tgcatatcgg caatttgttg agtggcatct
    12001 tctttttgac gttttgcttg ggcgatggct gcagaagcaa tattacgctc tgcttttaat
    12061 tcttctgatt gcactaatag agcacgacgt ttttcatcaa gttctttaag atgggtcagg
    12121 gtgtcttcag aaacaccgcg gttttttaat ttggcagcga cagtgtcaaa atcggtacgg
    12181 atacgtttaa gatctagcat acagaagctc ctttaagata gttattagta gctgtcagtg
    12241 aaacaaggct aagtaagaca gttgggtctt gtgattctct gacgatagaa aaagcacagc
    12301 ttatgaagat gctggagcgc tttggcgcgg ttccatccag cttcacaatc tgtgcactta
    12361 atctctattt tattgatgac acggtagaat ttcatatcat tttccctatc tgttcacagc
    12421 atccacagac tctctgaatg aaaaaaaggt attacttatc cgttaggact attataacaa
    12481 aaaacaagaa aaagtaaact caaatgaggg aatcttttcc actaaatagc aagttagagc
    12541 tactattctt tgctttcttg aaatgataaa tcggcactgc tcattatttt tttaatgtcg
    12601 aaaaaatttg ttaataaagg tttgcatcaa ggttggtaat gtaatcactt tctcattacc
    12661 aatatgttga cgagtgattt ttaagatttt tccagagtct ccagaagcaa ataaaaactt
    12721 gccttggtcc gtaaaaattt caaagtggcg gctaactttt tttcttgaaa cattagcccc
    12781 gatgtgattg atagctgtcc aaggaatttg aatataatca ttcacatttt tatcgttgta
    12841 aaattcaagg gccttgtcac cgagtaaaat atgaccaact ttgcctccca ttccaaggta
    12901 ggagacagct tttgtcttgt attcgacact agtgtttaaa gattgagcca tttaagttcc
    12961 tttcattgcg tagttgtagt tattatacca tattttaagt gggattttcc tgacataaag
    13021 cataaaaaag aagcctgagt tcatctcaga cttccattgg ttgattacat aatacctgca
    13081 aggtgagcaa ggataccaaa tgcaaacaag ccgatgatga ttgcgattgg agaaactttt
    13141 ttcttcaata accacatgca aaggaatgta aggagtaatc cagctaaacc tgggataaga
    13201 gagtccaatt gtccttgaag ggtttgagct tggactttat caaggctcat accaccaata
    13261 gcgttggcaa ggatagtttt caattcagca cctttaacag cgccatctgg gaagaccaca
    13321 taggcaccat ctgacaattg ttttccagga aggtcgatag taaagttgat agatacccaa
    13381 cgttgaacaa gcactgcaag gataaacatt ccaaggattg aagcaccttt agtaatgtct
    13441 tggaggatac cgcctgacat gtctttagta atttcagaac cagctttgta accaaattct
    13501 tgagtatacc ataagaaggc catacggata aggttccatc caaagaagaa cagaagtgga
    13561 ccaacgatgt tacctgttga agccaaagaa gcaccaagtg ccccaaggat aggacgaatc
    13621 gtaaaccaga atactgggtc accgatacca gcaagaggtc ccatcatacc gattttaacc
    13681 ccttggatag ccttgtcatc aattggcgta ccatttgcgc gttcttcttc aagggcaagt
    13741 gttacaccaa tgattggagc tgcaacgtat gggtgagtgt taaagaattc catgtggcgc
    13801 tcaagagcag ctgcacggtc ttcaggagac gtatacaatt ttttaagagc agggataagt
    13861 gcataagccc agcccatgtt ttgcatacgt tcgtagttcc aagaaccttg taagaattgt
    13921 gaacgccacc aaacacgttg acggtctgat ttagttaatt taatttgttc agtcatttgt
    13981 tcttacccct ttctagtagt cttctaagat gtcgccgatt ggatcagctg aacctgctgc
    14041 attaccaccg ttaccacctt ttttagaaag attaaggtag atgaaggcaa ttgctacacc
    14101 gataacaccc atagcgataa gggttaattg gctgatagct gcaagagcaa aacctagggc
    14161 gaagaatggc catacttcac gagtagccat catgttgata accatagcat aacctacagc
    14221 aacaaccatc gcaccaccga tttgcatacc ttcgttcaac cagtttggca tagcattcaa
    14281 aacagattgt acggctgaag taggaacagc aacaagaaga gctgcaggga cagcgatacg
    14341 caatccttga agaagaaggg caataaagtg gaagcgttca atacctgcga aattaccttc
    14401 agcggcagct ttgtcaccag cgtgtacaag ggcagttgac aaagtacgaa cgatcattgt
    14461 aaggaaaaga ccagcaacag caagtgggat agctgttgag taagcaaagg taattccttt
    14521 ttgagtaaag tcgccacttt tgaccatgat gatagcagct gcaacagagg caagggcagc
    14581 atcaggggca acggcagcac cgatgtttgc ccaaccaaga gcaagcattt gaagtgtacc
    14641 accaaggatg acaccagctt caaggtgtcc agttacaagt ccaatcaaag tacaggcaac
    14701 aagtggttgg tgcatttgaa attggtcgag gataccttca agaccagcga agaaggcaat
    14761 gataacgacc aaaattgcag aaataatcga aatatctgac atgttgtaat cctttcaaag
    14821 tatagtaaac gaggactttt tgctaataag ttagctagtc atcgttttaa aaccttatag
    14881 cgtttgaaac ttatttaatg ttagcttttt ggataagctc aaataagttt ttcttagaat
    14941 cgttaggaac tttacggacg tcgaatgtaa cacctaggtc gcgtaatttt tcaaaagtag
    15001 caacgtcttc tttgtccatt gataaaacgt tgttaaccat tgttttacca gttgagtgag
    15061 ccattgaacc aacgttcaat tcgttgattt caacaccacc ttcaaccgct cgaagggcat
    15121 cttgaggggt ttggaaaaga ataagtgcgt gtgtgttacc aaaacgagga tctttagaag
    15181 cttcaatcaa tttgctaatt ggaacaacgt tagctttgac accaccaggt gcagcctgtt
    15241 tgatcaattg tttgcgaagg tcatcttgag caacctcatc agaagcaaca atgatacggt
    15301 cagccttaga agctggagtc catgctgttg caacttgacc gtgtaaaaga cgagtgtcaa
    15361 cacgagcaag attgatcttt aatttaccat ctccgatgac agttccagca ggaatagctc
    15421 cttgaagtgc gttaacaact ttttcagttg cagcagtttc ttcaactggg ttaaggtctt
    15481 caggaagggc tttgataccg tccttagatt ccttaatgat gtttgcagca acttgttcaa
    15541 cacctgcacc agcatccata agacgttcag tgtaagcttg aataagcata ggcaagttga
    15601 gaccagtgat gatcgccatt ttgcggtcag gattttcacc tgccacacga ctagcttggt
    15661 taaatggaga accactccaa aggtcagcta gcacaaggat ttcatcatca gcatcaaatt
    15721 gttggatagc attgttgaag tgtccataca aatcatctgg tccttcgttt ggcatgaaag
    15781 taacaacttg aactttctct tgttcaccaa aaatcataga accagattga tgaatacctt
    15841 cagcaaattt accatggctg gcaataataa taccgatacc cattcttgtt cttcctcctt
    15901 taaaatattt ttcgttgaaa tgaagaagaa taatctcctt ccaaaactaa attttggcaa
    15961 ttctttttca cttaaacgaa attcaagaac gtttctattt taaaacgttt tcactaaaaa
    16021 atcaagccct ttcggaaaaa tagtacaaaa catgaaaaaa ttttcagaat ttaggattaa
    16081 ataggcagat tattgatatt aaaggtgttt tcaagctgtt taaaacaaaa atatgctgaa
    16141 aaatgttgaa attattaaaa tgattttcat tttttgatag ctgttgacag aagaagaacc
    16201 accattttct gaaaaatagt ggtttcgttt gctactacaa gaaaagttct tccaattttt
    16261 tggcaacacc gtcttcttcg ttggaaaaat taagctgctg atcagcataa ggcagtagca
    16321 cagggctagc atttttcata gcataaccag ttccagcaaa agctagcatc tcagtgtcat
    16381 tgtgttcatc accaaaggcg attaaatcct ttttatccat attgtaaatt ccaaggagat
    16441 agttcagagc gtaagcttta ttgacattct tagacgaaat ttcaagaatg ttgagagggc
    16501 ctccccaaga atcaatttca atttcatctt tgaagcaagc acgcatgttt ttagctaagg
    16561 catacttgtc ttcgtgatgc gtttgcatca ataaggcgtt tggatttcga gtgattttgg
    16621 taatctctaa tgccatgtcc tgagtaattt catcaacacc aaagagttgc gggtcgatac
    16681 tttctggatt ggtcatggtg atgtagacat tttttcgata ctcactggca ataaaatcca
    16741 tctggaaatc atcctgatat tttagtaacc ttagtaggta gcctttgtcc aaagtgacat
    16801 tatgttcata ggcccatttt tgttcaggca tgtgggtcaa ggccccatta aaagtgatga
    16861 ttggggtctt taaattgagc tgcagatagt agcccagtgc catgcggtaa ggacggcctg
    16921 ttgaaataat gacgtggtgg cccttgtctt ggacagcttt gatggttttt tgagtatagg
    16981 tagagatggt gttgtcatga tgtaataagg ttccatccaa atcaatggca atcaattttt
    17041 tagtcataat taaattatag caaattttgc tccaagataa agagaaaaga taagttaagc
    17101 gtattcatta gtaaaaaaga taggataact gtttttttaa tgaataaatg aagttataga
    17161 cgttgaaaag tgaacaaaaa aatggtaaca tattgttatt gttcatttta atacgaacaa
    17221 taacaataat aatgaggtgt caaaaagact tatctagtga taagcgcttt ttgattttac
    17281 ctactattta attaaggaga ctccatttca atggaaaagt tttttaagtt aagcgaaaat
    17341 gggacaactg tctcaactga gattatggct ggtttaacga ccttttttgc catgtcctat
    17401 attttgtttg ttaacccaag tattttaggt gcagcgggga tgccctctaa tgctgtcttt
    17461 ttggctacga ttatcgcagc agccatatca accttaatta tgggactatt tgccaatgtg
    17521 ccttatgcgt tggcaccagg aatgggactt aacgcttttt tcacttatac agttgttttt
    17581 gctttagggt tttcatggca agaagccttg gcaatggttt tcatttgtgg attattcaat
    17641 atttttatta ccgtaaccaa gtttcgtaaa agtatcatca aggcgattcc agttagttta
    17701 cagcatgcta ttggtggggg aattggtgtc tttgtagctt atttaggatt taaaaacgca
    17761 aatatcatta ctttttctat ctctgctgaa aatatagtaa tggtaaatgg tgttgaaccg
    17821 gctaaagcat cggctaaaac atttgcagat ggtctattat ttgtagacgc caatggtgga
    17881 gttgtaccta cgatttctag ttttacggat tccggtgtat tacttgctat ttttggttta
    17941 cttttaacga cagctcttgt gattcgaaat tttagaggtg ctattttaat tggtattgtc
    18001 gcaacaactc ttgtaggtat tcctttagga atagtggatg tgtccaacct caattttggg
    18061 atcagccata ttggtgaagc ttggactgaa ttaggtacaa ctttccttgc agctttcgat
    18121 ggtttgagtt ctctttttag cgattcaagt cgtttaccgc tagttttcat gactattttt
    18181 gcttttagtc tatcagatac ttttgacaca attggtacct ttatcggaac tggtcgtcga
    18241 acaggtattt tctctcaaga cgatgagaat gctttggaaa atagtatagg ctttagttca
    18301 aaaatggacc gtgcgctttt tgcagatgct atcggtactt ctattggggc tttggttgga
    18361 acttcaaata cgactaccta tgttgaatca gcagcaggaa ttgctgaagg tggacgtact
    18421 ggactaacag cagtctccac cgcagtatgc ttcttattat caatattgct attaccgctt
    18481 gtaggtattg tcccagctgc tgctacggct ccagctttaa ttattgtggg tgtcatgatg
    18541 gtgtcttctt ttcttgatgt taattggagt aaatttgcag atgctcttcc agcttttttt
    18601 gcagctttct ttatggcgct gtgttactct atttcctatg gtattgccgc tgcctttatt
    18661 ttctattgtc tagtaaaagt tgttgaggga aaaacaaaag atattcaccc tattatttgg
    18721 ggagcaacct tcttgttcat tgtaaatttc atcatattaa ctatcttata accaaataat
    18781 ttacttattt tgctactaac tgccgcttct ttaattgatt ttaaccttta atataaagaa
    18841 gcgtttttac tttacgaata ccttattgga gtcatcttct aggtagtgct tggaagtatg
    18901 ttttttttct gatataatgt tgctatgttt tatagtgaaa atgaatatac tcttaaagct
    18961 tacggagaaa ccctaggtac ttatttgtct attggagatg tgattgtatt gtctggcgac
    19021 ttaggtgccg gtaaaacaac attggcaaaa ggtattgcta aagggatggg gattagtcaa
    19081 atgatcaaaa gcccaactta tactattgtt agagaatatg aaggacgtct acctctttat
    19141 cacttagata tttaccgtgt tggtgatgat ccagactcta ttgatttaga tgattttctt
    19201 tttggtaatg gtgttaccgt tattgagtgg ggagaattat taggagaggg attattacaa
    19261 gactatttgc aaattaccat tactaaacga gacaaaggtc gtcaactaga cttgttagcg
    19321 catggtgagc gctctcgtca gcttctggag ataatgtcac atggttcagc aaagtctcgt
    19381 tattgaagaa ggcgtacctc aagatgcaaa agctgtactt tccttagtga cggcagctgc
    19441 caaagaaaca gattttataa caggcgtaga gactatatta gaggctactc ctcaagaatt
    19501 gtcagacttt ttatcaagaa gtcaaacctc ttttattgat ttttgcctgc tagctagatt
    19561 agatgaaaaa gtagtagggc ttttaaatct ttctggggaa gtattatccc aaggccaagc
    19621 tgaagcagat gtatttatgt tagttgctaa gacttaccgt ggttatggta tcggtcaatt
    19681 attgttagag attgctcttg attgggctga agaaaaccct tatatcgaaa gccttaagtt
    19741 ggacgttcaa gtaagaaata ctaaggctat ttacctgtat aaaaagtatg gttttcgtat
    19801 tgaaagtatg cgaaaaaacg acatcaaatc aaaaaatgga gatgacttag atgtttatca
    19861 tatgcgtaaa tctgtaagtc agtaagtgaa tcgatgaaaa ttggaaaaaa aatagtttta
    19921 atgttcacag ctattgtgtt aacaactgtc ttggcattag gtgtctatct aactagtgct
    19981 tataccttct caacaggaga attatcaaag acctttaaag atttttcgac atcttcaaac
    20041 aaaagtgatg ccattaaaca aacaagagct ttttctatct tgttgatggg tgttgataca
    20101 ggctcttcag agcgtgcctc caagtgggaa ggaaacagtg attcgatgat tttggttacg
    20161 gttaatccaa agaccaagaa aacaactatg actagtttag aacgagatac cttaaccacg
    20221 ttatctggac ccaaaaataa tgaaatgaat ggtgttgaag ctaagcttaa cgctgcttat
    20281 gcagcaggtg gcgctcagat ggctattatg accgtgcaag atcttttgaa tatcaccatt
    20341 gataactatg ttcaaattaa tatgcaaggc cttattgatc ttgtgaatgc agttggaggg
    20401 attacagtta caaatgagtt tgattttcct atctcgattg ctgaaaacga acctgaatat
    20461 caagctactg ttgcgcctgg aacacacaaa attaacggtg aacaagcttt ggtttatgct
    20521 cgtatgcgtt atgatgatcc tgagggagat tatggtcgac aaaagcgtca acgtgaagtc
    20581 attcaaaagg tattgaaaaa aatccttgct cttgatagca ttagctctta tcggaagatt
    20641 ttatctgctg taagtagtaa tatgcaaacg aatatcgaaa tctcttctcg cactatccct
    20701 agtctattag gttatcgtga cgcacttaga actattaaga cttatcaact aaaaggagaa
    20761 gatgccactt tatcagatgg tggatcatac caaattgtta cctctaatca tttgttagaa
    20821 atccaaaatc gtatccgaac agaattagga cttcataagg ttaatcaatt aaaaacaaat
    20881 gctactgttt atgaaaattt gtatgggtca actaagtctc agacagtaaa caacaactat
    20941 gactcttcag gccaggctcc atcttattct gatagtcata gctcttacgc taattattca
    21001 agtggagtag ataccggcca gagtgctagt acagaccagg actctactgc ttcaagccat
    21061 aggccagcta cgccgtcttc ttcatcagat gctttagcag ctgatgagtc tagctcatca
    21121 gggtctggat cattagttcc tcctgctaat atcaaccctc agacctaacg ttctgagggt
    21181 ttttatgttt aaaatatccg attttgaata taaaaaagac aggtatcaaa gatgatagct
    21241 gtctgtgatt tcaaataaag tatatgaggg agataatact atctggaatg gttgttagtt
    21301 aaaatgacgg tttggcaagt aggtgattca ctagaaatta gctcactatc ttcttgatat
    21361 ttggccatac gattttggat ttcagtgagg tgtgcttgtg tctcttggtt aaagtagcgc
    21421 catttatggg ccaagtcctg actaatattt tgaattactt ttccttgact gtgaatgagg
    21481 tcaaggtttg ctttaatgtt atctaaatca agttgggcag catcttttgc ttgtctactg
    21541 atggataaca gctcttttat ggtacaacgt ttttgatatg ctttgtaagc ggtaaaagat
    21601 aataatccga cggctatcac ggttttaact ttcatgaact aacctcctga ttgatttgtc
    21661 gggcgagctt ttccaagaca ggaaagtcag gctcatgagt ggtgtattga attgagatac
    21721 cgtcttcttc attataacga ggaacgagat gaacatgagc atggaaaaca gtttgtcccg
    21781 ctaaggcttc gttattgtta atgatattca tggcagtagc gccagtagct gactggatag
    21841 cacgagcaat tttaggaata cgagcaaaga gatgactagc tgtctcagca gtcatctcta
    21901 gtaagttacg aacatgttgc ttaggaatga ctagagtatg cccttttgta gtttgtgaga
    21961 tatctaaaaa ggcgaggacc tgctcatctt cgtagacttt cgaagagggg atatcccctt
    22021 gaatgatgct gcaaaaaata caattttcca ttttatatca ccttctctac ttgaatttgt
    22081 tataatatat tataagtata tcaaaaacta gaaagaaatt atatgttaaa cattaaaaat
    22141 ctaacaggag gatatcacaa tatccctgtt ttaaacgatg tctcattttc tgtagacaat
    22201 ggagagttag tcggtttgat cgggctaaat ggtgctggaa agtcaacaac tatcaacgaa
    22261 attattggct ttttgaagcc ttatcaagga agtatttcta ttgatggttt aactctagca
    22321 gaaaatgcag ttgcctaccg tcaaaaaata ggttttatcc cagaaactcc tagtctctat
    22381 gaagaattga ccttatcaga gcatatcaac accgtagcta tggcttatga tatcgactta
    22441 gaagtggcac aaaaacgagc acaacctttc ttggaaatgt ttcgtttaac tgacaaactt
    22501 gaatggtttc ctgtcaattt ttctaaaggg atgaaacaaa aagtcatgat tatttgtgcc
    22561 tttgtcattg atccaagtct atttattctt gatgaaccat tcttagggtt agacccttta
    22621 gctatttcag acttaatcca aacgctagaa gtcgaaaaag caaaaggaaa atctattttg
    22681 atgagtacac atgttttgga ctctgctgaa agaatgtgtg atcgttttgt gattttgcat
    22741 catggacaag ttcgtgccca aggaactctt gctgacttgc aagaagcttt tggtgaccgt
    22801 tcagcgagct taaatgatat ctatcttgca ttaacaaaag aggattaagt atgaaagcat
    22861 tatttctgaa acgccgtcaa gactttcaaa aacaacaaaa caaatacctt cgttacgtct
    22921 taaatgatca ctttgttttg gtgttgatgt ttttattagg ctttgctatg gtgcagtatg
    22981 gtcagctact aaaccatttt ccaacgaatc atctacctat tcaggtttgc cttgggatat
    23041 tgatcccatt attgctcagt atgggatcta tagcaacgta tctagaagag gcagatcagc
    23101 atttcttact tccaaaagaa gaagaagtga tttcttatat caaacaagct gagcgactct
    23161 cttttttgct ttggggaact ttgcagactg ctgtattgct ctttttatat cctattttta
    23221 gacgtttagg tctgtcttta tttattttta ttatcttagt tttgatatta ttggcactaa
    23281 aaagagtagt gcttagtcga aagacaagat attttttgag aggaaatcgt ttagattggg
    23341 caaaagctgt cgcatttgaa agcaatcgca agcaaagtat tttaaagttt tattctcttt
    23401 ttacaacagt caaaggaatt tctacaaaag tgaaagaaag aacttatcta aatcctcttt
    23461 taaaattagt taagcaaact ccttcaaacc tttggctgtc cctttatgct agagcctttt
    23521 tacgtagttc agattatttg ggcttatttt tacgactaat gctattaagc tcattatctg
    23581 tattttttat ccataatctt tatttgtcag taagtttagc actcattttt aactatttag
    23641 ttgtattcca attactttcc ctttattatc actacgatta ccattatatg actagtcttt
    23701 atcctgaaaa tagtcggagc aagaagaaaa atatgttaag ttttttacga ggtttaagct
    23761 ttttaatgtt aatcgtcaat atgctgtgtt gctcatcagc gccaaaagca ctcattttga
    23821 ttgtaggtat ggttttcata gcttgtatat atctacctta taagttaaag aagatcattg
    23881 actaagtagc ctaaaacaag taaaataggg gtaaacgact ataaaagata gaaaaggagg
    23941 gcgataaggt gacaacgacg gaacaagaac ttaccttgac tcccttacgt gggaaaagtg
    24001 gcaaagctta taaaggcact tatccaaatg gggaatgtgt ctttataaaa ttaaatacga
    24061 cccctattct acctgcctta gcaaaagaac agattgcgcc acagttactt tgggccaaac
    24121 gcatgggcaa tggtgatatg atgagtgccc aagaatggct taacggccgt acattgacca
    24181 aagaagatat gaacagtaag caaatcattc atattctatt gcgccttcac aaatctaaaa
    24241 aattagtcaa tcaactgctt cagctcaatt ataagattga aaacccatac gatttattgg
    24301 ttgattttga gcaaaatgca cccttgcaaa ttcagcaaaa ttcatactta caagctatcg
    24361 ttaaagaatt aaaacggagc ttaccagagt tcaaatcaga agtagcaacg attgtgcatg
    24421 gagatattaa acatagcaat tgggtgatta ctactagtgg tatgattttt ttagtagatt
    24481 gggattctgt tcgtctaact gatcggatgt atgatgttgc ttacctgttg agccactata
    24541 ttccacggtc tcgttggtca gaatggctgt cttattatgg ctataaaaat aatgacaagg
    24601 ttatgcaaaa aattatttgg tatggtcaat tttctcacct gacacaaatt ctcaagtgtt
    24661 ttgacaagcg tgacatggag catgtgaatc aggagattta tgccctcaga aaatttagag
    24721 aaatatttag aaagaaataa tgcgagttag aaaacgaaaa ggtgctgagg agcacttagc
    24781 taataaccca cactatgtga tattaaatcc agaagatgcc aagggccgtt ggcatgacgt
    24841 ttttggaaat gaccgtccta ttcatatcga agttggttca ggaaagggcg gatttatcac
    24901 agggatggcc ttgaaaaatc ctgatattaa ctacattggc attgatattc aattatctgt
    24961 cctaagctac gccttggata aggtattagc ttcagaagta cccaatgtca aacttctgcg
    25021 agtggatgga tcaagtttaa ccaactattt tgaagatggt gaggtggata tgatgtacct
    25081 caacttttca gatccttggc caaaaaccaa gcatgaaaaa cgtcgtttga cctacaagga
    25141 tttcttagac acttacaagc gtatcttgcc agaacacggt gaaattcatt ttaaaaccga
    25201 taatcggggc ttgtttgagt acagtttagc tagtttttct caatacggca tgaccttgag
    25261 acagatctgg cttgacttac acgctagtaa ctatgaagga aatgtcatga cagaatatga
    25321 agagaagttc tctaataaag gtcaagtcat ttaccgagtt gaggcaaatt tctagtagta
    25381 ttttgtttca aaatatgata acataaagga gttgatacag tattaacttc tttagtaatg
    25441 gagaggtcgc atagtggctt agtgcgcacg cttggaaagc gtgtagtcct taacgaggct
    25501 cgggggttcg aatcccctcc tctcctttta tcctcttgat atatcaaggg tttcggggtc
    25561 ttcgcccgtc tttcacccgt caaatttgag attttgaaaa atgtttttga cctgatggtc
    25621 atttttttct tttaaacttt ctatctgatg agcgtaaact ttgagtgtga tgttgagatt
    25681 ttcgtgcccc aacagcttgg atactgatat taaatcaacg ccctgcgcta tcaaataaga
    25741 agcgtaagta tgccttagcg agtgattggt tagatttctg ccagtcactc tttttataac
    25801 tttgttcgtt gcattatttg acgctccaaa gcatacacga ccgagtttat tatcctgata
    25861 atagtcgctc ttaaaatttc ttagtatctc aaggctattt ttatcaatcg gtaccttcct
    25921 gatggactgc tcgtttttgg tcggaccgaa attttgagaa attgaataat caaaagtttt
    25981 attaatatcg atatagccat tctcaaaatc aatgtctttc caagtcaacc cttgaacctc
    26041 tgcaaatcgt aaaccggtga cggctatgat atacgttgtc aggtatgatg ggtacttgac
    26101 tttgcttttg gcaaccttga taaaggcgag gtattctgat tcttccatga atttctctga
    26161 ctcttcttta gcgggttttt gcgatctaac aatggcccca tcggcaaaat tatccctaat
    26221 aatgccatca cgaatggcca ttttacaagc acccttgatt tgataatgaa atttatccag
    26281 agtttgttgg gctacttttg cgccaaagtc attaaggact tgctgataaa aggtgtgtgt
    26341 gatactcttg agcttccgag tcccaaaata atgttcgatg tgcttaaaat ttttggtgta
    26401 tgtctgccat gtctttgcgg taatgtgagg ccttttatat atgtctgccc aacgtctgtt
    26461 gtagtctaaa acagtaatat ctaaaaggtc tgcggtcagc gtatttaaat caatttctgc
    26521 ttgctgagca gcgacttttg caagtgtttt tgttttaaat ccacgttttg atttttctct
    26581 ttttttacct tgactgtcac gataggtgat gcgatactcc cacccagaac ctaattttcg
    26641 ataaaatgcc attgttttca cctcattttt ctgttaaaat gggtacaaga aaacgacctt
    26701 tttaatggtt gtttcttata cggttttgcc tcacgctctc ctcgccaaat ttgagcgtgg
    26761 ggtttttttt atttaaagaa attattaaca cttacatact gagcctgcgt aagcttagtt
    26821 tttaaggttt taacttctcc ggtttgtata tttcttaagg ctaccgttgc ttttccaggt
    26881 atttcttcag aagtggttgt ggcagtagtg ttaatggttc cttttttctt tctagcccca
    26941 ccagccattc cgccgataat ggttccaacg cctggtgcca aaactttacc tattgctgcc
    27001 cctcctagaa cactactaga acgccctttt tgagtagttt tcccttttgt tactgttttt
    27061 tcaataattc gtgacccatc aaattgaagg ctaacaaact cataaagctc aggagtttca
    27121 gaataaaaac cgatataata ttttccatct atggtttttc gtatagccgt ttgtgctcct
    27181 agttctaaat ttagggcagg gggtaggatt attttgctct cttgtgaggc tttttttctt
    27241 agttcgttag ctttaattgc accgtcttta gctttccctg cagctgttat ggcaaattct
    27301 tttaacttag ctatatccat gcttgtctcc ttaactaatt aaaaactcta attcttcttt
    27361 gatcatcact tcgtcagcga ttgaggtcag ttcatacttt tccatgaatt ggatgtagtt
    27421 gaaatcctcc atattatccc aataggatag ctcttctttt aagagatggt gtatcataca
    27481 tctatctgct tgtagctctg ctttttcttt gtttagtttg taataactcg cagtatgttc
    27541 tctatgtcct agttcatgat agatgacttt gtgtttatat ataccgtcaa gataggtgtc
    27601 aatcgcaatg acgttgtgtt ttttattaaa cattccaggg gtgtttgtac ccctaccgtc
    27661 aaagtacact aaatcgattc ctttttcctg acagactgtt tctggtgtca tcatagagca
    27721 gtcctctcta ttttctattt ttgatgcgcg tttccaatat agatgtgata aggtctatat
    27781 cctcgtcgtt gagttcgtga ccgtcgaaga agaaagtctc ttctgcatct ttttttagat
    27841 caattgcgac cgaagcgtgc ccatcttgcg caatcttagg attatcagtt cgacctaata
    27901 ggtaatcggt tgatacgtga aagtagtcag cgattagttg tagtctttct gctgaaggct
    27961 ttttattttt aattgtatag attgaatttc tactcaatcc caatttttcc tcaagcaatc
    28021 ccaaggaaat acctcttgat tttgcaagtt ctttaattct ttcgaatgtt gaaaacattg
    28081 atttgtcagc ctttctatga gatgacaaaa aatatctata aaaaagcatg taaactactt
    28141 gactgattac aaactttagt ctagaatata atttgtaaag cgaatataaa agcgaaacaa
    28201 aaaacgaaaa ttaaaactaa aaaaatataa ctttggcgag tttataagta gtttaataat
    28261 gtttttgttg gtgtttttac tataccttga ttttagaata tagtttgtaa aatgtcaata
    28321 ctaaagttga aaaacttcgc gattattttc gctttacttt taataaaaaa actcccgatt
    28381 gggagtagaa aggagagagt agtatggatg aaaaaaatcc actcgaacag tttgaagagt
    28441 tttgcaagaa taattcattt gagtatgtta aaggctgggt tgatggcatg caatcagttt
    28501 taaatattct ctcaatggaa ttatctaaaa aaaatggatc tacttcggag gttgattgaa
    28561 tacatcgttt tcttctaaat atttagagag cgctggtgtc attgctgagc ctaacatggt
    28621 cattagtcct tgagcaacag tattgtttac ttctgcttct gactgctttt gaatattttc
    28681 taactctaaa gtgtgagctt ctttcatttt ctcaagttct cgaaaatgat ttttttccat
    28741 agcttcaaaa tcatgttgat actgtttttc aagcctttct aggtcattac tatgattttt
    28801 ttcgatagta gtcatctcat gattgaactt tttttctaac gattcaatat cagatctgtt
    28861 cttatatctt gaagctaaga agctaataat agcagaaatt gcagctggca aaacagctgt
    28921 tgcaatagtt aaccagaaat taaatttttc cataataaac ctcaacattt ttatttatat
    28981 tatatcagaa aggagagcag atgagtcaac aacacaaaaa atggtcagct ctagttgaac
    29041 agcgattaaa agaaaaaggt tggacaagag tcgacttggc acttgcggct ggtttgcgga
    29101 gttcaggaac gattactgac ttacttacta aaggaaaagg aagcgttgac cttaaggtta
    29161 gggtttcaaa aattcttagt atccgtgagc cgtgggagtt gttcgaaaat gaatagtaca
    29221 caaaaaagcc actgctggaa cagtgactta gctaaaacat attaaaggaa ttttatcatg
    29281 gatagcagat tattacaaat gctagatgag tttgaagcgg gccttattga tcgcaaaatc
    29341 aaagtcatga aaatgattaa caatgagacg gaaatttatc cgctagaact caataaaaag
    29401 caagtcagta agatgtttgg ggttgaccct aaaacatttg acgcaagatt taacagccac
    29461 aaagatttcc cgcgtattga aacggggggt cgggaaaaat acccacgaga tttagccatc
    29521 gagtggtatc acagaaattg gagtataaca tgaacaaatt agaactattt ttattagcaa
    29581 caaccgtcat cttagcggtc attgctaggg tgcaacacga agtcatcaaa aaacacaatt
    29641 cgccagagaa taaacgcaga atttttaggg aagtggcttt agaaaacagc aagaaatgga
    29701 gtgcagaacg ttatgtctaa atgggaatta caaaagcaac tgttggctaa tgcgacagat
    29761 tttgagagta cagtagaagc tctgtttgag ttaaatgaat tgggtgaaat ctcggacgag
    29821 gagctcttgt taaatttgag aagtagctac aggaaatact cagaggaaaa actttgtatt
    29881 attgacaaac tcattaagct tggaggcgca gaatgatgac aacttttgaa aagattatca
    29941 agaaccttaa tcggattgag agggaattag ttaagcccga agctgaaaga cgagatagct
    30001 tacctatcct atctgctcag ttgagtgcta tcaagcaaga tttaaaattg atgctttgga
    30061 ttgaacttcc ggcgttaaat aacgtagaaa aatatgaagc tctttatcaa ggaaatgatt
    30121 ttaaattcag tgaaactttc ttagagcgtc aagcgacgag aaaagccttt tggagacgat
    30181 tagctaaaga aactttcaaa gaagaccagg ataagaggaa ctttgttaag ttggctgaga
    30241 aagaatttaa aggtgcaact ttgtcatggc aagaattttt gtggggtaaa aagaaatgaa
    30301 catatcacta aaatttattg atgaaaccct agctggttta aatgatattt tacgccaggg
    30361 ggggctctct tgttcccaaa gccaagccct ggcggacgca gtttttatat taacagcttt
    30421 aaaacaagta attgaggaga gaaaatgaac tatttagaat atgcactagc ttatcttgaa
    30481 cgtgagctag aaattattga cgacgaagtt atcgaagttg agttgccggg cggagattgg
    30541 gagtttgtgc ctaaccccta ctacgaggaa ggtttacatg atagcccaca ctatcgtagt
    30601 caggttgcta aagacattct tgatattaaa ggacttttgg ggaggtgagg ctattgattg
    30661 catcaaaaaa gacggcttag gaaaccgtca acaattatac acaattaaat tataacacag
    30721 aaagagagaa acacaatgat tgaagtaact tttaaagcag agagcatggc aggtgttttc
    30781 gatgctatgc gtgaagctct ggatatgccg aagacagtaa ccaaggatgt tgttgaagaa
    30841 aaaccagctc ctaaaaagaa agaagagtct gtaactttga cattagctga tattaagaaa
    30901 atggctaaag ccaaggttga agaagggaag tcaaaggaca tcaaggaagt cttgaaagag
    30961 atgaacgtcg caaaagttgg tgaacttgaa gaataccagt ttgctgagtt tgttgagaag
    31021 ttggaggccc tctaatgcca gtagaaaatc acgcactact gtctgcttct agtgctcaca
    31081 gatggcttta ttgccctatg ctgccgagat tagaagcaga ctaccctagc cgcgataccg
    31141 tatacactca agagggcaca agcgcccatg agctttctga aatcaaactg atgtacaagt
    31201 ctggtaaaat caccaagcgt aaatttaaca cgttaaccaa ggcttttaag gaaaactcag
    31261 acttctacaa cgaagagatg gaagagatga cggaacttta cacagatatt gttatggagc
    31321 acctaaatgc ttatgaggat gccgaaattg aacttgaaaa acggattgat tttagcgact
    31381 gggtgcctgg cggttttggg acttcggatg tcgtcatttt ggcggatggg gtcattgaaa
    31441 ttattgatct taagtatggc aagggtatgc ctgtgtctgc taaccaaaac ccgcagatgg
    31501 ggttgtacgc tctgggagct tacgcttcct acgatatggt ttatgacttt gaccgtatca
    31561 agatgacaat tattcagccg cgtttagatt cggttagttc tgttgacatt tacgtagagg
    31621 agcttctgta ttgggcggat aatgttgtct tgcctatggc cgctcaagca gacgcaggta
    31681 ttggcgactg gaacctaagt gaaaaagtat tgcagtggtc tcctgtcgca gctaaattgg
    31741 tgccaagagc gcaagaaaac tgggaattaa ttgataaata tgactatcag gagcctgtct
    31801 atttatctga tgaagccgtc gcagagatcc ttgacaaagc ctcagctatc aagaagtggg
    31861 ttgagtcagt tgaagcctat gccctgaaag aagcactctc aggaaaagaa gttccaggct
    31921 ataagattgt cgaaggtaga agtaatcgtg tgcttactaa taaggaggca gctgcgacaa
    31981 tacttgagaa aaacggcttt gaagatatct acaaaccaaa agagctactg tccatggggg
    32041 ctctagagaa gatggtcggt aagaagcgtt ttgaggacat gatggccttt atccttgata
    32101 aaccacaagg taaacctgtc cttgtcaaaa atagcgacaa gcgacccgcg ttaaatagct
    32161 tagaacaagc aataaaggag tttgaataga atatgaagat ttataaagta aaagttaagt
    32221 ttagacaaac atgccataaa aaattcaagg gtaagaaata cagctacttt agttttgaag
    32281 agttgcgggt aggtgacctt gtggttgtcg aaactgttta tggccctagc gtagccaagg
    32341 taacagaagt tgttgatgcc aatgagcttt ttacagctac cagctatgtt atttccaaag
    32401 tggatacttc acttttagcg ggcaagaaag agttaatggc taccgccttg actgtaaaag
    32461 caaatattga tgcggaaacg gctgagtttg cagcgaaata taaagatgct tattatttag
    32521 gcctgtttga tcagtacaaa aaccaaaatc cagaattagc agagttatta acacaattaa
    32581 aagaattata ggagaagaat tatgacacca agcacaacta aagtagtaac cggaaaagta
    32641 cgcctaagct atgcagcttt actagagcct aaagcctttg aaggtcaaga ggctaagtat
    32701 tcaacagtta tcttaattcc aaaaacagac aaagtcacaa tcaagaaaat taaagacgcg
    32761 cagaaagctg cttatgaagc tgccaaggac aataaactca aaggggttaa atgggagcgc
    32821 gttaagacaa cgcttcgtga cggtgacgaa gagatggata ctgaagagca cccagagtac
    32881 gctggacaca tgttcatgtc agtgtcaagc aaaactaggc cgcagattat cgaccgttac
    32941 aaaaaccccg ttgactccgc agacgaagtt tactcaggag tatacgcacg agtatcatta
    33001 aatgcctatg cctacaatac tgcgggtaac aagggtatct cttgtggtct gaataacgtt
    33061 cagattgttg ctaaaggaga ctaccttggc ggtcgttcgt cagctgatgc agactttgac
    33121 gagtggaacg aagaagagga cgaagacgac attttatagt agagggcctc tttagaggct
    33181 cctcattttt aaaggagagg tatgagacat ttaaatattg atattgaaac ctatagttcg
    33241 aatgacatca aaaatggggt ttacaagtac gctgacgctg aagattttga gattttactt
    33301 ttcgcttact ctatagatgg cggagaagta gagtgccttg atttgacaag gcagtctcta
    33361 cctgaagaca tcaaagatat gttatttgat gataaagtcc gaaagcacgc ctttaatgcc
    33421 caattcgaaa gagtttgtct cagtcgttac ctcggcctac cttactattt agatcccgca
    33481 caatggcagt gtacgatggt acttgcacaa gagctgggtc tgcctgcaag cctggaaaaa
    33541 tgtgcgctgt atttaaaatt agcgcaagaa aaagacgcag caggtaaaaa tctcattaaa
    33601 tatttttcgg taccctgcaa gcctacaaaa gccaacgggg gaagaacgag gaacctgccc
    33661 gagcatgatc ctggaaaatg gcaaatgttt attaactact gtatgcaaga cgttgttgtt
    33721 gagatggcaa ttgccgaaaa actagagtca gttcctgtgc acgaccgtga gtgggattac
    33781 tacgtctgcg accagagaat caacgacaga ggcgtggcac ttgataaaga gttagttgct
    33841 tcggctttgt attgtaaaga tgttaagatg gaaagtttgt ctggtgaact aaaggctcta
    33901 acaggacttg ataatcctaa tagcagggcg cagctgctac cgtggctaaa agaacacggt
    33961 tattcggcta atgggctgac taaagctgac gttgaacagg aacttaagaa ggccgaagga
    34021 gagcttaaga gagttttaga acttaaacta caaaccgcga tgtcaagtct aaaaaaatat
    34081 gaagctatgg aaagagctat gtgctcagac ggacgagttc atgggctact tcagttttac
    34141 ggggctagcc ggacaggaag atgggcgggc agagttgtcc aagtacagaa cttagctagg
    34201 aattatataa aggatctaga tgatgctaga gagtatgtta aaaagcgtga tattgatgct
    34261 gtggagattt tatacgatag ccttaacgac actttaaagc agctcgtgcg aacggcactc
    34321 gtggctaaag atggctatac cttctatgtc tctgacttct cggcgattga ggctagggtg
    34381 attgcatggt ttgctggaga gcagtggagg cttgacgtgt tttctacgca cgggaaaatc
    34441 tacgaggcgt ctgccagtca gatgttcgga attccaattg aggagattga caaggaacta
    34501 cgccaaaagg gcaaaatttc agagttagca cttggctatc aaggaggtcc tggagcgctt
    34561 aagcagatgg gggctctaaa tatgggagtc aaggaagagg agcttcaagg gttagttgat
    34621 gactggcgca gggccaataa gaaaatcgtc caattttgga aagacgtaca aagagccgcc
    34681 atcaaagcca tcaaatcgag agcaccgata aaacttggaa aaatacgatt tagataccgg
    34741 aaaggtttcc tctttataac attgcctagc ggtaggaact tagcttatgc aagagccaag
    34801 gttgagccag gcgactatgg agacaaaatc atctatgagg gccaaggaga tagggcctat
    34861 ttcacagcgc aagagacgta cggcggtaag cttgtcgaaa atatcgttca ggcgacggcc
    34921 agggatattc tagctgaagc gcttctgagg attgaagctg caggctatga tgttgttttc
    34981 cacgttcatg atgaggctat tatcgaaggt tcaggcctga taatcgaaga ggttaatgat
    35041 ttgatggctc aggctcctga atgggcggag ggtcttcctt taaatagcga aggctatgta
    35101 acaaagtatt atatgaagga ttagatagat gaagcaagaa aaactaatag taaagtcttc
    35161 tcccctgcaa gagcttcata tcgcaacagg tagttcgcga acagctaaga catggaaaaa
    35221 tatcacgcta acttggcagg agctggttga gaggttagag aaacctacag tcacccaaga
    35281 gacgtttgcg gagtaccaga agatgtctcg agcagaaaaa gggcaagcaa aagacgtagg
    35341 gggctttgtc ggtggatggc taaagcaagg taaacggaaa aatgaaaacg ttcaaagtag
    35401 gtccttggtt gcgcttgacg cagatagccc aagtaaagat ttcttagata ggctagacct
    35461 gcttgcagat tatgcattcg tactctacag tactcacagc cactcaaaaa aagctgctaa
    35521 gtaccgtctt attatcccta ctgaccgttt aatgatgcct gatgaatatg agccagtcgc
    35581 tagatatttg gctaaccaac taggcatgtc aaactttgat gacacgactt atcaaagcgt
    35641 acgcttgatg ttctggccga gccactcaag agatgccgac tttacgttta aatataacga
    35701 cgaggctttt ctgagtgttg atgaggtgct tgacacatac ccggactggc atgactcaag
    35761 cttctggcca gaaagcccga cgcacgctgt taaaagacag cgtgaagcta aaaaacaagg
    35821 tgacccgctt agtaaaaaag gacttattgg agccttttgt cgtaactatg acattagaca
    35881 ggccattgca acattcttat ctgaggttta tgaagaagga acgactcctg ataggtacac
    35941 ctacactgat ggctcaaccg caaacggctt agttatctat gatgatgtct tcgcttatag
    36001 ccatcacggg acagatcccg tgggggatac gcttgtaaat gcctatgacc ttgttcgtat
    36061 ccataaattc ggagagcaag atagcgaggc taaagataat actcctacta ataagttgcc
    36121 gtcaagtaaa gcgatgaatg cttttgtctc tgacttaccc gaaattaaag accatttaat
    36181 ggcggaggct ttaggcgatt tcgatgaaga gttaccagtc gaagatgaca gaagctggct
    36241 tgaaattgat gagaggggcg aaccggaggt caatagttat ttgctagcaa cgcagattat
    36301 taaggaggtt ccgatttatt gggatggctt agaattttta cgctacgacg ctaaaaaagg
    36361 catctggttg ccaaacgctg aggaatattt gaagagttat atctcaacta agaaactcgg
    36421 taaaattact aagattaggc acattagcga aaccgtcgta gcgattaaag cacaggcttt
    36481 ttcaagtgaa gtgtttaccg agagtgatct taacaagata gtgctagcga atggagtcta
    36541 tgacctgagg gataacaact ttaagactaa gtttgatcca gaattgcatg ccaggtcaag
    36601 ccatcccgtt gtctatgacc ccgaggcgac ctgtgaaacc tttgagggtt ttcttagaga
    36661 gaccgtcgga gctgaaaata tagatttcat ctttgagtgg tttggctata acttttatcg
    36721 tgaatacact attcaaaaaa tgctattcat ctatggtagc gggggcactg gcaaatcaac
    36781 actaattaat attttacgtg aaatgatagg cgctgataat tattcagccg tgacactgca
    36841 gtacctgatg caagaacgct ttgcaaaaat cggcttatat cgtaagacag ctaacttcga
    36901 taccgatgct aaacctcaat acttagcaga tggcgcagca cttaaaatgt tgacggggga
    36961 ggatactatt cacgcagacc gtaagaataa agagccgatt aacttttaca attatgctaa
    37021 gctgtctttt gccatgaatg agctcccacc tatgcgagat ttcagcggag gacttaaacg
    37081 ccgcatgatg atcctcgaga tggataaggt tttaacgcag gaagttaagg cgaaataccc
    37141 gctagataag attatgagcg aggtgcctgg tatctttaac agagcgatgg aggggcttag
    37201 aaaggcctta agtaagagag atttcagtat tagtgccagc atgaggtcaa gtgtcgagaa
    37261 atgggaaaaa ggcaacgatg tcgtagctat gttccttgaa gacgagtgtg aacttggcga
    37321 agacttcaaa gttcctgtta gggatgtcta cccagcttat aaattctatt gtcaggattc
    37381 aggctacaaa cctttggcaa aaaatgcatt taaccatcgg ctaagagagc taaattatga
    37441 aaataaaaac gttaaatctg atggaaagca agccaaaaat tgggtcggct ttaggttaaa
    37501 aagtgagttt taggggttac ttttttggaa ttagagtttg gtaaccctag aaaaaagtta
    37561 ccaagttacc ggttttttca aactttaaaa ataaaaaatt taaaaataat ttttaaaaaa
    37621 ccaaaaccga attggaaaaa tcggtaactt agtaactcga cccttagaaa tgggttcgaa
    37681 aagtaacccc ggtagctttt tggtagccct aagaggtctt tcatagcaat agtttagccc
    37741 ctgtggttac caatctacca ct
//
LOCUS       DAUGQX010000017        37710 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUGQX010000017 DAUGQX010000000
VERSION     DAUGQX010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37710
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.017"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..272)
                     /locus_tag="VIA51_000771"
     CDS             complement(<1..272)
                     /locus_tag="VIA51_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682726.1"
                     /translation="MTIDEALQNLRDNFNKIMNVLKNDWKALLFLAIAIFGMMVTVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRASEDRARQTKRIAELT"
     gene            complement(269..439)
                     /locus_tag="VIA51_000772"
     CDS             complement(269..439)
                     /locus_tag="VIA51_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682727.1"
                     /translation="MKRYIEVKDEWKSATDHLNDFIDKNKYAKVTVVGYQVVQLSPYG
                     RDLTYILAEVEE"
     gene            complement(436..672)
                     /locus_tag="VIA51_000773"
     CDS             complement(436..672)
                     /locus_tag="VIA51_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEQ8682728.1"
                     /translation="MIEELVHKPKHYNHGEIDLIESWYKTYPWDQFVAIMESHIDKYI
                     KRHRYKGNATQDLEKALEYTKRLIEYWLIESVEE"
     gene            complement(914..1270)
                     /locus_tag="VIA51_000774"
     CDS             complement(914..1270)
                     /locus_tag="VIA51_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682729.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADKEEADRVYRSVKYYKKL
                     NRLPPPDVLEWFQRIYTTKEMIMLIKQSYRLKQKKTDEDDKIYEKWMFKNYGDVKLVK
                     KIKRTDALERARRMGL"
     gene            complement(1267..1707)
                     /locus_tag="VIA51_000775"
     CDS             complement(1267..1707)
                     /locus_tag="VIA51_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEQ8682730.1"
                     /translation="MVKFIIPIEPKPQKRPRFSRWSGAYEDGDMMAWRKQVTDYVKNN
                     YEGPYFDDGLKVDVTFYLKAPELVSKKPSERAKDKTKQKYQDYINELLYVPKKPDLDN
                     LEKAVYDSISKSEVVWTDDNIIVEHTTRKLYSPNPRIEVKINEL"
     gene            complement(1707..1910)
                     /locus_tag="VIA51_000776"
     CDS             complement(1707..1910)
                     /locus_tag="VIA51_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682731.1"
                     /translation="MANRYRQRIYAVYDGDSFVDVGTKHELAERLGVTADTIVFIASP
                     AHKKRRPDGRHAEFIGYEDELEE"
     gene            complement(1916..2341)
                     /gene="ssb"
                     /locus_tag="VIA51_000777"
     CDS             complement(1916..2341)
                     /gene="ssb"
                     /locus_tag="VIA51_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8682732.1"
                     /translation="MINNIVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGER
                     EADFINCVIWRQSAENLANWAKKGALIGVTGRIQTRNYENQQEQRVYVTEVVAESFQM
                     LESRNSQQQSGQDNSSQNDNSQPFGNSNPMDISDDDLPF"
     gene            complement(2334..3008)
                     /locus_tag="VIA51_000778"
     CDS             complement(2334..3008)
                     /locus_tag="VIA51_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEQ8682733.1"
                     /translation="MRKSESITEYAKAFCKAQLEVKQPLKDKDNPFFKSKYVPLENVT
                     EAITKAFANNGISFSQDPTTNAENGYIDVATLVMHTSGEWVEYGPLSVKPTKNDVQGA
                     GSVITYAKRYALSAIFGITSDQDDDGNEASKPNKTNQSQKPTNKTSKGTSFQTPKISN
                     IQVETYKSDLSDIAKATNQNVKELTKWLTDTLKVKSLEDLRTEQIVSTDDLINKLKKR
                     AGQKND"
     gene            complement(3009..3491)
                     /locus_tag="VIA51_000779"
     CDS             complement(3009..3491)
                     /locus_tag="VIA51_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEQ8682734.1"
                     /translation="MAYLYELEGIAAYLESLDLDDETFQNTLDSIDFQSDLENNIEYF
                     VKMLKNAQADVEMYKAEKEAFYKKQKQAEAKVEKYKETIRRAMELSQKKKVDAGMFKV
                     SLRKSKKVEILDETKIPLDYMQEKIEYKPMKSEISKALKSGIDISGVELIETESLQVK
                     "
     gene            complement(3513..3767)
                     /locus_tag="VIA51_000780"
     CDS             complement(3513..3767)
                     /locus_tag="VIA51_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682735.1"
                     /translation="MVGIRINGELVTFDSNFRDALIFTIDCLRGSEEPMLKQTYQTFK
                     DYTDEDLMDYIETEFDVWPELIVNRKIDSKWSTKQHILDD"
     gene            complement(3748..4101)
                     /locus_tag="VIA51_000781"
     CDS             complement(3748..4101)
                     /locus_tag="VIA51_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682736.1"
                     /translation="MVMPLDELEKRIFCYLPIGSNMMVNSKEICRTFDIKDPKTLRDI
                     IHGMVMKGYLIGSSRRKGGGYYLIDNDDERAEAISSLESQVRKEQKRINILKNGNLNE
                     FVEIANEVRNGWNQN"
     gene            complement(4242..5024)
                     /locus_tag="VIA51_000782"
     CDS             complement(4242..5024)
                     /locus_tag="VIA51_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ8682737.1"
                     /translation="MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTV
                     CPDCHREELDNQNALHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRADTAKH
                     KEMLYWAKTMANDWFSGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTD
                     LLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPAEIRKIYGERIASRIRKGCDKSHIMEFDGMEDERMKLWN"
     gene            complement(5011..5841)
                     /locus_tag="VIA51_000783"
     CDS             complement(5011..5841)
                     /locus_tag="VIA51_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEQ8682738.1"
                     /translation="MADNKKYYYLKLKENFFESDEAIILESMPDGYIYSNILLKLYLR
                     SLKNDGLLMFNNLIPYNAQMLATITRHQIGTVEKAIQIFRDLQLIEILDNGAIYMTNI
                     QNFVGKSSTDADRKRIEYAKAKQLGQISMKCAEKSPPEIEIELDKERELDKKIDINID
                     KELEVEEEIKDSSSAANVNNLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVK
                     EAITRAADNSKRSFGYVNSILRNWRQNGILTMVKVEEEQRQFQSRKSKQEEVSEYDTW
                     "
     gene            6055..6516
                     /locus_tag="VIA51_000784"
     CDS             6055..6516
                     /locus_tag="VIA51_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682739.1"
                     /translation="MIALVHSIYYNMVKIKLSDCYISRVDKGYDWMYDFSISNLSNVS
                     VIIKKIELYNKDGKLISDNGFNPFQKYEADMQNEADDYYGLSMPNYYMPLDYQWESSP
                     FKSDTEVYPSSRENFSYYLDEKPVKIKITTDKRIHQFRKYQLFFPHFDNNS"
     gene            6647..6856
                     /locus_tag="VIA51_000785"
     CDS             6647..6856
                     /locus_tag="VIA51_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682740.1"
                     /translation="MGPNYFHVQFKLGEKVSYNTPSAEGREVIPIKGAEVTKMIFADG
                     NELLSVIHNETVDVYASFPIVLEYH"
     gene            complement(6966..7166)
                     /locus_tag="VIA51_000786"
     CDS             complement(6966..7166)
                     /locus_tag="VIA51_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682741.1"
                     /translation="MTRFAIQRLREEKKMSQEELANKSGVSRTTISLIETDKSTTVKL
                     STLQKLAVALDVPIGYFFKHNV"
     gene            7240..7626
                     /locus_tag="VIA51_000787"
     CDS             7240..7626
                     /locus_tag="VIA51_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682742.1"
                     /translation="MFDYFKLYIIVLETFVETKPDDAYSLFDNLSLNSEFVKFSKDLD
                     KNIVISGTLEVIDNLLDDCLIKGKRRPTKDITFYFFDGVTTTGYLYLQSLKDNNFSSR
                     LKNVLKEEGIPLTPTSITRTIAKLTL"
     gene            complement(7615..7824)
                     /locus_tag="VIA51_000788"
     CDS             complement(7615..7824)
                     /locus_tag="VIA51_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682743.1"
                     /translation="MRPKKYPYSQKNYPAPKLHNVIETDNQFLIDDKRIHYVIEDSVK
                     TKTLGDGYVEVTLSIIAKSFTKSQG"
     gene            7878..8477
                     /locus_tag="VIA51_000789"
     CDS             7878..8477
                     /locus_tag="VIA51_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682744.1"
                     /translation="MDLLKNTNFLIPLISAIVSVSSIFISNWLGYRSQIRKLKFDEEK
                     EIYLTLYVPLIKWMNSQSFNNKSYYWLVAFPRYTTNAQDFLTGLLLKNFEKLPVSVAM
                     RYSEYTLNSATSLHFYRNTEYDYDYETFAKKASELFDLIIEQLLTEGTILSQKLSLPN
                     LSKSTLENFLADKKNYIGPRFLSLETHNKPLRPERPLPF"
     gene            complement(8507..8665)
                     /locus_tag="VIA51_000790"
     CDS             complement(8507..8665)
                     /locus_tag="VIA51_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682745.1"
                     /translation="MNWKKLMLGNLEHTFTSHDGKEKTSIEFEGGLLPALLVLGGITW
                     LAAWFITK"
     gene            9022..9846
                     /locus_tag="VIA51_000791"
     CDS             9022..9846
                     /locus_tag="VIA51_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682746.1"
                     /translation="MKLGEIIKNFREEKKLSMDRFAEKSGLTKGYISMLEKNEHPKSK
                     KPIIPTEETLLKVAKGMGVDIDFVLSKLDSDQEIQINISPKNMLNMDNPSTPTTPKVE
                     LIPSTLQKINSTSSQLEHSRQIIVLDTAETLLEQQKEIKNNEDTIAELFSYNYYDHAA
                     SAGTGQYLNDVQVEKIELPVDYDADFVIPVYGDSMEPKYHSGDYVFVKLSVELTDGDI
                     GVFEYYGDAYIKQLLINDEGAFLHSLNSKYEDIPIDRDSDFRIIGEVVGSYSGNHS"
     gene            9882..10775
                     /locus_tag="VIA51_000792"
     CDS             9882..10775
                     /locus_tag="VIA51_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P63C domain-containing protein"
                     /protein_id="HEQ8682747.1"
                     /translation="MENEVLHATHEGKLVLDNTTLDVAVLNNGQRIITQAGVFKALDR
                     PSRGNTRVIGIPTFMDAKNLQPLISKDLRGVINKIEYRDLNGRIQLGFDANILPLVSD
                     LYLKAREIGAIKSEAQMRTAQKAEMLVRSLAKVGVTALVDEATGYQYERERFELQKIF
                     KAYISEELLKWQKMFPDDFYMEIFRLNGWSYDVQSIKRRPGVVGKWTNELIYKRLPDG
                     VLEELKRRTPKTKKGQYKARFFQTLTPDIGHPDLNAQIYKVLGIMRISSNWKDFKEKF
                     NVMTSREDGIIELDLEFDEDK"
     gene            10896..11984
                     /locus_tag="VIA51_000793"
     CDS             10896..11984
                     /locus_tag="VIA51_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ8682748.1"
                     /translation="MKIKSYKKENGETAYKFLLYAGYVNGKRKYIRREGFKTKQAARE
                     TLISLQAELDKPKSSMTFGALTDQWLKEYEKTVQCSTYLKTERNINKHILPKLDKVKI
                     GDINPLLIQRLTEEWCNDLKYGGKILGLVRNILNLAVRYGYINNNPALPITPPKIKRK
                     RKMNNNFYTLDQLKQFLELVEKTDNIEKIALFRLLAFTGIRKGELLALTWDDLNGNTL
                     SINKAVTRTQVGLEIDVTKTKSSDRLISLDDETLEILLELHETFPTSTLMFQSESGGI
                     MTPSLPRKWLLQIIKGTDLPQITIHGFRHTHASLLFESGLSLKQVQHRLGHGDLQTTM
                     NVYTHITQSAIDDIGTKFNQFVTNKQLD"
     gene            12347..12967
                     /locus_tag="VIA51_000794"
     CDS             12347..12967
                     /locus_tag="VIA51_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEQ8682749.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(13224..15488)
                     /gene="glgP"
                     /locus_tag="VIA51_000795"
     CDS             complement(13224..15488)
                     /gene="glgP"
                     /locus_tag="VIA51_000795"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEQ8682750.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(15523..17016)
                     /gene="malQ"
                     /locus_tag="VIA51_000796"
     CDS             complement(15523..17016)
                     /gene="malQ"
                     /locus_tag="VIA51_000796"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEQ8682751.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(17131..18150)
                     /locus_tag="VIA51_000797"
     CDS             complement(17131..18150)
                     /locus_tag="VIA51_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8682752.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            18396..19643
                     /locus_tag="VIA51_000798"
     CDS             18396..19643
                     /locus_tag="VIA51_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8682753.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKENDYLTKLQQFDKDIAATK"
     gene            19917..21278
                     /locus_tag="VIA51_000799"
     CDS             19917..21278
                     /locus_tag="VIA51_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8682754.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            21278..22114
                     /locus_tag="VIA51_000800"
     CDS             21278..22114
                     /locus_tag="VIA51_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8682755.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            22272..23069
                     /locus_tag="VIA51_000801"
     CDS             22272..23069
                     /locus_tag="VIA51_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8682756.1"
                     /translation="MTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHI
                     SNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLV
                     CLNEDSTEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAA
                     LKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLID
                     ESLDQFFVNSSQKLCCPRFSPKKGQVILETIEWAKKRQPDKKHNLLV"
     gene            complement(23185..24000)
                     /locus_tag="VIA51_000802"
     CDS             complement(23185..24000)
                     /locus_tag="VIA51_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEQ8682757.1"
                     /translation="MPDKKQFPISYISHCLSPRAMFASRAQFTWWQNLLIIVFLNALI
                     MIPVTLHYANMTTYPLERIVTKSLSPITDKTYQALTQGKIEKDTFQGQSLIRRDGELV
                     LAVLPTKVDLEQLASESTRQIIVTKKEWRFVTPDGKELRAHVRGQQQSLADLTTVKAV
                     KDFVNQQWYDSNKASVLGFLLLTFVLMVCVGTLIVIGLGAFFLTLTKRSRLFMIRNFS
                     EGLGLMVNCLAWPSLLAIALSFFIQDPVLIMNCQVFGTLLMLTWVFYKTQFRD"
     gene            complement(24022..24882)
                     /locus_tag="VIA51_000803"
     CDS             complement(24022..24882)
                     /locus_tag="VIA51_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8682758.1"
                     /translation="MRKTYVSISMKRKRFFTQLLTYLYLISLVIVILFPILVTVSSAF
                     RPGNTTAFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTGYA
                     YSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVRPMIAVQSLWAFMGPFGDF
                     MLAKFLLRAQENYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKNFV
                     SGLTSGGTKG"
     gene            complement(24879..26186)
                     /locus_tag="VIA51_000804"
     CDS             complement(24879..26186)
                     /locus_tag="VIA51_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8682759.1"
                     /translation="MVENQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLEL
                     LEIVVLGIPALTGLYSLGSVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKLVA
                     HQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVI
                     ANQSFIRGKRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVD
                     FGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADLYEAATVDGATVLQK
                     FRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYK
                     LTTQTSPQFSMASAVTLIISVIVISVSLITFKKFKAFDMEERS"
     gene            complement(26261..28396)
                     /locus_tag="VIA51_000805"
     CDS             complement(26261..28396)
                     /locus_tag="VIA51_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclomaltodextrin glucanotransferase"
                     /protein_id="HEQ8682760.1"
                     /translation="MRELHIKTYKLLTKSAVLLGLISFPLTVSAADNASVTNKADFST
                     DTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQGIIAKIKDGYLTDMGISAI
                     WISSPVENIDSIDPSNGSAAYHGYWAKDFFKTNQHFGTEADFQQLVKVAHQHHIKVVI
                     DFAPNHTSTAEKEGTTFKEDGALYKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNINPKVDQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFVFGEWFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKVL
                     ENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGVPNIYYGTEQ
                     YATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALAYGTTEQRWISDHVLVFE
                     RKFGNHVALVAINRDQTNGYTITNAKTALPQNSYKDKLEGLLGGQELIVGADGTISSF
                     ELGAGQVAVWTYEGEDKTPQLGDVDASVGIAGNKITISGQGFGNSKGQVTFGEISAEI
                     LSWSDTLITLKVPTVPANYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTV
                     PGEQLYLMGDVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKK
                     DSIGNVLWTSPETYSIKTGHEAQTITIKK"
     gene            complement(28422..30125)
                     /locus_tag="VIA51_000806"
     CDS             complement(28422..30125)
                     /locus_tag="VIA51_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEQ8682761.1"
                     /translation="MNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGP
                     KYGYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNRGDWEKGDSYVNMGW
                     LEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTPIFQSISNHKYDISDYYAIDPQF
                     GTKYDLQELIDLAHKMGIKIILDAVFNHASSDAVEFQDVLRYGKESKFFDWFMTHDEH
                     PSMDLVNYETFAGCNYMPKWNTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHD
                     FWRRFRQAVKAEKADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTS
                     KQLAEKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFIFMGI
                     PCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQQPALQEGAISID
                     YDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILTSNGVTKNKKQLLQDGYIVFS
                     N"
     gene            complement(30291..31550)
                     /locus_tag="VIA51_000807"
     CDS             complement(30291..31550)
                     /locus_tag="VIA51_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8682762.1"
                     /translation="MSWNWKKTSVLGTLSLASVLPLTACVSGGGKGVKETDGKTIVVS
                     VDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPTGASPDVFLAPFDRV
                     GGLGTEGQIAEVTLGNSKEFDDTVKKLVTIDGKTYGAPDVIETLVTYYNKDLVPQAPK
                     SFTELEVLQKDSKFAFASEPGKSVGFLAKWTDFYYGYGLIAGYGGYIFGDKGTKPSDL
                     GLGNDGTVEGLNYAKQWYGTWPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFK
                     DAGVNFGVMEIPTLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFY
                     DKTQEIPANLTARNYASKEGNELTKAVISQFESAQPMPNIPEMAEVWEPGANMFFNVA
                     SGKEEASKAAKEAAKTIKEAIEQKYAE"
     gene            complement(32165..33148)
                     /locus_tag="VIA51_000808"
     CDS             complement(32165..33148)
                     /locus_tag="VIA51_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8682763.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(33179..34429)
                     /gene="dltD"
                     /locus_tag="VIA51_000809"
     CDS             complement(33179..34429)
                     /gene="dltD"
                     /locus_tag="VIA51_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEQ8682764.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(34422..34661)
                     /gene="dltC"
                     /locus_tag="VIA51_000810"
     CDS             complement(34422..34661)
                     /gene="dltC"
                     /locus_tag="VIA51_000810"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEQ8682765.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(34679..35935)
                     /gene="dltB"
                     /locus_tag="VIA51_000811"
     CDS             complement(34679..35935)
                     /gene="dltB"
                     /locus_tag="VIA51_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEQ8682766.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYRENANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRHFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(35932..37470)
                     /gene="dltA"
                     /locus_tag="VIA51_000812"
     CDS             complement(35932..37470)
                     /gene="dltA"
                     /locus_tag="VIA51_000812"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEQ8682767.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(37482..37625)
                     /locus_tag="VIA51_000813"
     CDS             complement(37482..37625)
                     /locus_tag="VIA51_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEQ8682768.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT        11726 a         7459 c         6321 g        12204 t
ORIGIN      
        1 tgcgtaagtt ccgcaattcg ctttgtctgt ctagctctat cttcgctagc acgtttaagc
       61 tgcttttgtg tcctgcttag ctgtgtacgt agtcctgtga tttgcgactc gtaatattgt
      121 cgtgcgtcgc gatagctaaa atacgacacg gttaccatca tcccaaatat tgcgattgca
      181 agaaacaata gtgctttcca atcgtttttt aggacattca ttattttatt aaagttatca
      241 cgtaaatttt gcaacgcttc atctatcgtc attcttccac ctctgccaaa atataagtca
      301 aatctcttcc gtaaggagaa agttgtacga cttgataacc aacaactgtc acttttgcgt
      361 acttgttttt gtcgataaaa tcgttcaggt ggtctgttgc acttttccat tcgtccttaa
      421 cttcaatata tctcttcatt cttccacgct ttcgattaac caatattcaa tgagacgctt
      481 tgtatattcg agtgcttttt ctaaatcctg agtcgcattg cctttgtatc tatgtcgttt
      541 aatgtattta tcaatgtgac tttccatgat tgcgacaaac tggtcccatg ggtacgtctt
      601 ataccacgac tcaatcaaat caatttctcc gtgattataa tgctttggtt tatgtactaa
      661 ttcttctatc atcactccac ctctctcaaa taatttacta tcgttttaca cacgctctca
      721 tttggcaata ttctgcgttc taagagcgct tttaattgcc aagtataaat gcctatctta
      781 tctgctaaaa cgtcatcaga catctttatt ttgcatctgt gagctattaa cagctctgat
      841 atatcgtaag gcaacagatt atcgtaagat ctaggtgtat atttaatatc gttatgccac
      901 tgtctgtgtc ttttcataga cccattctcc gagctctttc tagtgcgtcc gtgcgtttga
      961 tttttttaac gagcttaacg tcaccgtagt ttttaaacat ccacttttcg taaatcttgt
     1021 catcctcatc tgtctttttt tgtttaaggc ggtaagactg cttgattaac attatcattt
     1081 cctttgtcgt gtaaattcgt tggaaccact ccaatacatc aggtggcggt aatctgttta
     1141 gttttttata gtatttgaca gatctataga ctctgtcagc ttcttctttg tctgcgatgg
     1201 taatgttatc gtctaaaaac gctttaattg acggctccat ttgtttgtaa aaatcatcta
     1261 ctagtgtcat aattcgttta tttttacctc gattctggga tttgggctat acagcttacg
     1321 tgtagtgtgc tcgacaatga tgttgtcatc tgtccacaca acctctgatt ttgatatgct
     1381 gtcatatact gctttttcaa ggttgtccaa atcgggcttc tttggcacat ataagagctc
     1441 atttatataa tcctgatact tttgtttagt cttatctttg gcacgctctg acggcttttt
     1501 agacaccaat tctggtgctt ttagataaaa agtaacatca acttttaaac cgtcgtcaaa
     1561 ataaggccct tcgtaattgt ttttaacata gtctgtgacc tgcttccgcc atgccatcat
     1621 atctccatcc tcgtaagctc cactccatct gctaaagcgt ggacgttttt gcggttttgg
     1681 ctcaatcggt attataaact taaccactac tcctccaatt cgtcttcgta tcctataaac
     1741 tctgcgtgtc tgccatctgg tctcctcttt ttatgagctg gcgacgctat aaaaactatt
     1801 gtgtcagcgg taacaccaag tctttctgct agctcatgct ttgtgccaac atctacaaaa
     1861 gagtctccgt cgtagaccgc atatatcctt tgtctatatc tgttagccat atcatttaaa
     1921 acggcagatc atcgtctgaa atatccattg ggtttgaatt gccaaacggt tgactgttat
     1981 cgttttgcga agagttatct tgaccagatt gttgctggct atttcgactt tccaacattt
     2041 ggaaactctc tgcaacaact tccgtcacat agacacgttg ttcttgttgg ttttcgtagt
     2101 tacgtgtctg aatacgaccc gtaactccga tcaaagcacc ttttttagcc cagttggcta
     2161 aattttcagc agactgtcgc cagataacac agttaatgaa atctgcttct ctctccccgt
     2221 tttgctcttt aaatctgcgg tttaccgcaa gtgtgaacgt agctacagct acttgactcg
     2281 ctgtatagcg aagctctgcg tccttggtca tgcgaccaac tagcacaatg ttgttaatca
     2341 tttttttgcc ctgctctctt ttttaattta ttaatcaaat catcagtcga tacaatctgt
     2401 tctgtgcgta aatcttccag tgatttaact tttaaggtat ctgttagcca ttttgttagc
     2461 tctttgacat tttgatttgt ggcttttgca atatcgctta aatcagattt ataagtctct
     2521 acttggatat tgctgatttt cggggtttgg aagcttgttc cttttgacgt tttatttgtt
     2581 ggtttttgcg attgatttgt tttgttgggt ttgctagctt cattgccgtc atcatcttga
     2641 tcgcttgtta tcccaaaaat tgctgatagt gcgtagcgtt ttgcgtaagt gataaccgaa
     2701 ccagcgcctt gtacatcatt ttttgttggt ttaacactta aaggtccgta ttccacccat
     2761 tcgccactcg tgtgcatgac tagcgttgcg acatcgatat aaccgttttc tgcgtttgtt
     2821 gttggatcct gcgaaaaaga tatcccgtta ttagcaaagg cttttgtaat cgcttccgtc
     2881 acgttttcta gaggcacgta tttgcttttg aaaaaggggt tgtctttatc ttttagcggt
     2941 tgctttacct ctagctgagc tttacaaaag gctttagcat attctgttat actttctgat
     3001 ttcctcattt actttacctg caaactttct gtttcgatta gttcaactcc agatatatca
     3061 attccagatt tcaaagcttt cgagatctca gatttcattg gtttgtattc aattttttct
     3121 tgcatgtaat caagaggaat ttttgtttcg tccaaaatct ctactttttt gctttttcgc
     3181 aaagacacct taaacattcc agcgtcaact tttttctttt ggctcaattc cattgcacgc
     3241 ctgattgtct ctttgtattt ttccactttt gcttctgctt gcttttgctt tttgtaaaaa
     3301 gcttcttttt cggctttata catttcgacg tcagcttgag cattttttaa cattttgaca
     3361 aaatactcaa tgttattttc taagtctgat tgaaaatcaa tgctgtcaag cgtattttga
     3421 aaggtttcgt cgtctaaatc taaactttcc agataagcgg cgattccctc aagttcatat
     3481 aaataagcca tgttatttcc tctttctgta ttttaatcat ccaaaatgtg ttgtttagtg
     3541 gaccacttgc tgtcaatctt gcgattaacg attagctctg gccatacatc aaattctgtc
     3601 tcgatgtagt ccatcaagtc ttcgtctgtg tagtctttaa aggtttgata agtctgtttt
     3661 agcataggtt cttcgctgcc tctaagacag tcaatcgtaa agataagcgc atctctaaaa
     3721 ttgctatcaa aggttacgag ctcaccgtta attctgattc caaccatttc gcacctcgtt
     3781 agctatttct acgaattcgt tcaagtttcc gttttttaaa atgtttatcc gcttttgttc
     3841 ttttctaact tgactttcaa gtgagctgat agcttctgca cgctcatcat cgttgtcaat
     3901 tagatagtac cctccgcctt ttcgacggct agaacctatc aaatagcctt tcattaccat
     3961 tccgtggata atgtctctca aggttttcgg gtctttgatg tcaaatgttc gacaaatttc
     4021 ctttgaatta accatcatgt tacttcctat cggcaaataa caaaatattc ttttttctaa
     4081 ctcatctagt ggcattacca tattaaatct ctcctaaaac gtgacttttg agcactctct
     4141 ccacgctctc aattcttcaa ttttctttgt tcggacatct tcatctagcg ccatgatttt
     4201 tgccgcatgt tcctcggata gcccgaaaaa tgttgttagt gtcaattcca tagcttcatc
     4261 ctttcgtcct ccatgccatc aaattccatg atatgacttt tgtcgcagcc ttttctgata
     4321 cgggatgcaa ttctctctcc ataaattttt ctaatttcgg caggtgtcag attggtagta
     4381 atgattgtgt ttgtgcgctt gttaagcaag ctgtaaataa tgcttgtgga ccagtcacta
     4441 actttttcgg cacctagatc atctagcacc agataatcga catcttttag cttatccatc
     4501 caaaatgctt ccttgctaaa gtctcgcttt atctctgaca gtaagtcagt gacatttaca
     4561 agcaagccta attttttcgt tttatcagac aatcccctaa tgatgctata agctaaatga
     4621 cttttgcctc gtcctgcttt gccagtcatg atgatgtttc ccttaccacc actaaaccaa
     4681 tcgttagcca ttgtctttgc ccaataaagc atctctttgt gtttagccgt atcagcccta
     4741 aaattgtcaa atgatgcatt ttccaactcg tcgtccataa ttgataattt tttgagatag
     4801 tacagtcgct tgttttcaag ctctctctca tattgctttt ggacgtgcaa agcgttttga
     4861 ttgtctaatt cttctctgtg acaatctgga catactgtca aaccagtctt gaggactgtg
     4921 atgtatctac aaccatgttt ttcacagaca gcatcttctt tcttggtgtt ttgttgataa
     4981 gatatagcga ttttagcaag tgcgtcttcg tcaccaagta tcatattccg atacctcttc
     5041 ttgtttagat tttctagatt ggaattgcct ttgttcttct tcaactttaa ccatcgtaag
     5101 gattccgttt tgtctccaat ttcgcaatat agagttaacg tatccaaaag aacgtttaga
     5161 attgtcagca gctctcgtta tcgcttcctt aacaacatcc acttccattt ttgtgatggt
     5221 gatatagtct gacaactgtt caaactgatt cggagataag atgccaattt cttgttgaaa
     5281 ataatcagat ataattttta agttatttac attagcagca gaagatgaat cttttatctc
     5341 ttcttctact tctaactctt tatctatatt tatatctatc tttttatcta actctctctc
     5401 tttatctaac tctatctcta tctctggtgg agatttctcc gcacatttca tggagatttg
     5461 tccaagttgt ttagcctttg catattcaat tctttttctg tcagcatctg tgcttgattt
     5521 accaacaaaa ttttgaatat ttgtcatata tatcgcaccg ttatcgagaa tttcgattaa
     5581 ctgtaggtct ctaaaaattt gaatagcctt ttcgacagtg ccaatctgat gccttgtaat
     5641 tgtggcaagc atttgtgcgt tgtaaggaat aagattgtta aacattaata agccatcatt
     5701 ttttaaactt cttagatata acttgagcaa aatattgcta tagatatagc cgtcaggcat
     5761 actttctaaa atgattgctt catcactttc aaagaaattt tcctttaatt ttaagtaata
     5821 atactttttg ttatctgcca tttatctccc ttcttcaaaa atagctttca catttcttat
     5881 cttttaacgt ctcaataatt ccatctaaaa catctgatcg gtttttaagc tcattgtact
     5941 ctttgacaga tattgtgata aaatctttgt tatcttttgt agtatcgcta tatccgagca
     6001 ggtaagcgac cgatacatca aaatgatctg ctagtaattg cgctaattgt tgctgtgatt
     6061 gctcttgttc actctatcta ctacaacatg gttaagataa aattatctga ttgttacatt
     6121 tcaagagtag ataaaggtta cgattggatg tatgatttta gtatcagtaa cttatcgaat
     6181 gtttcagtca ttattaaaaa aattgaactt tacaacaaag atggaaaact aataagcgat
     6241 aatggcttca atccctttca aaaatacgaa gctgacatgc agaatgaagc tgatgattat
     6301 tatggattgt caatgccgaa ttattatatg ccattagatt accaatggga gtcatcgcca
     6361 tttaagtcag atactgaagt atatccatct agtcgagaaa atttctctta ctatttagat
     6421 gaaaagccag ttaaaatcaa aatcacaact gataagcgta ttcatcaatt ccgaaaatat
     6481 cagttattct ttccccattt tgacaataat agttaagata gcgatattcg ttaataaaat
     6541 taagataagt gctgccgtta gtagcatttt ttcttttctc cttttattag ttttgttcct
     6601 cctgcgtgct ataataaagc tatcattacg aaaggaggaa aaaagcatgg gtcctaatta
     6661 ttttcatgtc caatttaagt taggcgaaaa agtatcgtac aacacgcctt cagcagaagg
     6721 aagagaagtc atccctatca aaggtgctga agttacgaaa atgattttcg ccgatggtaa
     6781 cgaattgtta agcgttattc acaacgaaac cgttgacgtt tacgctagct tcccaattgt
     6841 tcttgagtat cattaattcg ttatttctaa accagcaatc gcccgctact gcgtttgttg
     6901 gtttttcttt tccgtaaaaa attcgatttg cttgcatagt gtcctttcca gttttgttta
     6961 acacgttaaa cattatgttt aaaaaaatat ccaataggta cgtctaaagc gactgccaat
     7021 ttttgaagag tgcttagctt aaccgtagta gatttatcgg tttcaataag agatatagta
     7081 gttcgtgaga ctccagattt attggctagc tcttcttgag acattttctt ttcttcacgc
     7141 aatctttgaa ttgcaaacct cgtcattccc ccacctcctt tctatctgtt tttagttcct
     7201 ccaatctgct ataatatggg cagaaaggag gtgaatgtga tgtttgacta tttcaaactt
     7261 tatataattg tcttggaaac cttcgtggaa accaaaccag acgacgctta tagcttattt
     7321 gataatctaa gtcttaacag tgaatttgta aaattctcta aagacttaga taaaaacatt
     7381 gtaatatcag gcactttaga agtaattgat aatttacttg atgattgctt gataaaagga
     7441 aaacgtcgcc caacaaaaga tattactttc tattttttcg atggcgtaac aacaactggt
     7501 tacttatatc ttcaaagtct taaagataat aatttttcga gccgtttaaa gaatgtcctt
     7561 aaagaagaag gtatccctct tacaccaact tctatcacaa ggactatcgc caaactaacc
     7621 ttgtgatttt gtaaaactct tggcaattat ggaaagtgtt acttcaacat agccatcgcc
     7681 aagggttttt gtctttacag aatcttcaat aacataatga atccttttat catctattaa
     7741 gaactgatta tcggtttcaa tgacgttatg aagcttcggc gctggataat ttttttggct
     7801 atacggatat tttttggggc gcatctattc cacccccttt ctgtggtata atttaaataa
     7861 aatgattgga gaaaatcatg gatttattga aaaataccaa ttttttaatt ccgttaattt
     7921 cagcaatagt ctctgtttct tctattttta taagcaattg gcttggttat agaagtcaaa
     7981 tcaggaaatt aaaatttgat gaagaaaaag aaatatacct aaccctctat gtaccgttaa
     8041 taaagtggat gaattcgcaa tcattcaata acaaaagtta ttattggcta gtggcgttcc
     8101 ctagatatac aacaaatgca caagattttc tgacaggctt gttgttaaaa aattttgaaa
     8161 aattaccagt atcagttgct atgagatact ctgaatacac cctaaattct gcaacctctt
     8221 tacattttta tcgtaacacc gaatacgatt atgattatga aacatttgcc aaaaaagcat
     8281 ctgaattatt tgatctcatt attgaacaat tgctaacaga agggacaata ttatcccaaa
     8341 agctaagctt accaaactta tccaaatcca ctttagagaa ctttttggcg gacaagaaaa
     8401 actatatcgg tcccagattt ttatcactag aaacccataa caaaccccta agacctgaaa
     8461 gaccactgcc attttaactc ccccctttcc gccccttgtg ggctttttat tttgtaataa
     8521 accaagctgc taaccaagtg ataccaccta acaccaacag cgctggcaat aagccacctt
     8581 caaattcgat gcttgttttt tctttgccat catgactagt aaacgtgtgt tctaagttgc
     8641 caagcattag ctttttccaa ttcatgcaac ctctcctttc attcttgcgg agatacagcc
     8701 aatgtgctaa actaaactta ccccgttagg gggagaggac ttcttagccc tctaattatc
     8761 ctcaccactc tattgagtag tgaatcttaa gcttaaacca aagaatcttg atttcgactt
     8821 ctagttcttt gcgtttaggc tttttgttta gcctagattt catcagctgt acctcctttc
     8881 gttttgctta atcccttaag cttgattata gtttaacacg ttaaacattc attgtcaagc
     8941 gtgttaaaca aaaatattga attatttttt gttgtgttgt ataatgtatt aaacaatcat
     9001 tctaggaaga ggtttttaac attgaaatta ggggaaataa taaaaaattt cagggaagaa
     9061 aaaaagttat caatggatag gtttgctgaa aaatctggtc ttactaaggg gtatatttca
     9121 atgcttgaaa aaaacgagca tccgaaatct aaaaaaccaa ttatccctac agaagaaact
     9181 ttgttaaaag tagcaaaagg gatgggggtt gatattgatt ttgttttgag taaattagat
     9241 tccgatcaag aaatacagat taatatttct cctaagaata tgttaaatat ggataatccc
     9301 tccactccca ccaccccaaa agtcgaactt atcccatcta ctctacaaaa aataaactct
     9361 acttcttctc aactagaaca cagtagacag ataattgttt tagatacagc tgagacttta
     9421 ttggaacaac agaaagaaat taaaaacaac gaagatacta ttgccgaatt attttcttac
     9481 aactactacg accacgcagc ttcagctggt acaggtcagt atctaaatga tgtacaagta
     9541 gaaaaaattg agttaccagt cgattatgac gcagactttg ttatccctgt ttatggtgat
     9601 tccatggaac cgaagtatca ctctggggat tatgtatttg ttaagctatc cgtagagctt
     9661 acagatggcg atataggcgt ctttgaatac tatggtgacg cttatatcaa acagctactt
     9721 ataaatgacg agggggcatt tctgcacagt ttaaatagca agtatgaaga tataccgata
     9781 gatagagata gtgattttag gattattggt gaagttgttg gaagttattc gggaaatcat
     9841 agctaacgaa gctacggttg tgaatgagtt taggagaaaa tatggaaaat gaagttttac
     9901 atgcaactca cgagggtaaa ttagtcttag ataatacaac tcttgatgta gcagttttaa
     9961 ataacggtca gcgaatcatc acccaagctg gtgtttttaa agcattggac agacctagta
    10021 gaggcaatac ccgtgtgatc ggaataccta cttttatgga tgcaaaaaac cttcaaccat
    10081 tgatatcaaa ggatttaagg ggtgtgatca acaaaattga atatagggat ttaaatggta
    10141 ggattcaatt aggttttgat gctaacattt taccgctagt atcagattta tatttaaaag
    10201 ctagagaaat tggagctatc aaatcagaag ctcagatgag aactgcacaa aaagcggaaa
    10261 tgttagttcg ctcacttgcg aaagttggtg ttactgcttt agtagatgaa gctactggtt
    10321 atcaatatga gagagaacgt tttgagcttc aaaaaatatt taaagcatat attagtgaag
    10381 aattgctaaa atggcaaaag atgtttccag atgattttta tatggaaatt tttagattga
    10441 acgggtggag ctacgatgtt caatcaatta aaaggcgtcc aggtgttgtt ggtaaatgga
    10501 caaacgaatt gatttataaa agactgcctg atggagtgtt agaagaatta aaaagaagaa
    10561 ctccaaaaac aaagaaaggt caatataaag ctagattttt ccaaacttta acaccagata
    10621 taggacatcc tgatttaaac gctcaaattt ataaagttct tgggattatg agaatttcat
    10681 ctaactggaa agatttcaaa gagaaattta atgttatgac atctagagaa gacggtataa
    10741 ttgaattaga tttagaattt gatgaagaca aataaaaaaa gccccacgct ctcaaagttt
    10801 ggcgactctg agcgtgaggc aagacagtat aagaaacaac cattaaaaag gtcattttct
    10861 tgtacctatt ttatcaaatt gaaagatggt atgcaatgaa aattaaatca tataaaaagg
    10921 aaaatggtga aactgcttat aaatttcttt tgtatgccgg ttatgttaat ggaaaaagaa
    10981 aatatattag gcgagaaggt ttcaaaacta agcaggctgc aagggaaacc ttaattagtt
    11041 tacaagctga acttgataaa cctaaatcaa gtatgacatt tggagcattg acagatcaat
    11101 ggctaaagga atatgaaaaa accgttcagt gcagtaccta cttaaaaaca gaaagaaata
    11161 ttaataaaca tattttgcca aaacttgata aagtgaagat tggagacatc aacccactac
    11221 ttatccagcg gcttactgaa gaatggtgca acgatttaaa atatggagga aaaattcttg
    11281 ggcttgttag gaatatctta aatctagctg ttagatacgg atatatcaat aacaatccag
    11341 ctttgccaat tacacctcca aaaataaaaa ggaaaagaaa aatgaataat aatttttata
    11401 cacttgatca acttaaacaa ttccttgaac tagttgaaaa aactgacaac attgaaaaaa
    11461 tagccttgtt tagattatta gcatttactg gaatacgaaa aggggagctt ctggcactaa
    11521 cttgggatga tttgaatggt aatactctat caattaataa agctgtcaca cgtactcaag
    11581 ttggactaga aatagatgtt acgaagacaa aatcgagcga tagattaatc agcttagatg
    11641 atgaaacttt ggaaatttta ctagaacttc atgaaacttt tcctacttct actcttatgt
    11701 tccaatctga atcaggtgga attatgacgc caagtttacc acgaaaatgg ctattgcaaa
    11761 ttatcaaagg gacagactta ccacaaatca caattcatgg tttcaggcac actcatgcaa
    11821 gcttactttt cgaatcaggt ctatccttga aacaggtgca acatagatta gggcatggag
    11881 atttacagac aactatgaac gtatatactc acatcacgca atcggcaatt gatgacattg
    11941 gaactaaatt caatcaattt gttactaaca agcaactaga ttgacaacta attctcaaca
    12001 aacgttaatt taacaacatt caagtaactc ccaccagctc catcaatgct taccgtaagt
    12061 aatcataact tactaaaacc ttgttacatc aaggtttttt ctttttgtct tgttcatgag
    12121 tttccgttat ccctatagcc ataccatcac gcttaccgat actccatcaa taccactcaa
    12181 aaccttgtca tatcagatct ttttgaccat ttttttcatg aatatctaaa aaaaagaatc
    12241 aaaatagtac taaattcccc atagcgcatg cgctatgggg aatcatagct atatcttgtt
    12301 tataatttat gatataatac agcaaaaata gtttaggaaa taacatatga caaaaaaaca
    12361 cttactaaca cttcttctca tctctttttt tactagcttt ttggtagctt gttcaacaac
    12421 gaaagataaa gagcctcaac cgtctgattc agaaatcatt actccccgac tacaccaagc
    12481 cgctcatcaa gataaacgcg ctaactttga aaaaattaaa cttgcgactg ttgattcctc
    12541 atttacagga gggacaagcc ttgaagaact tatttcactc tttggagagc ctagccaaca
    12601 tgatccaaaa acagcaggcg aagtaacaat cgacgcttat acttggcagt ttgatcaagt
    12661 tactctcact gttaatcttt atcaaaatag tagtattgtt aaaaccatct ctaattttac
    12721 ctttgcaaga gagttaggct tatcgcaaaa ggaataccaa caattacaaa aaggaatgtc
    12781 ttatgaagac gttaaaaaga tcttaacaga acctgataat tatagccaag cgtcatctag
    12841 tgatcatcaa actttgcaag cgatttgggt tagtggctta aagacagata caagcggagc
    12901 taatatttct ctcgtttttg aaaataatca gttaacagaa atgtctcagg taggacttga
    12961 agaataaaaa atgagtaata tattttgcta aaaagattga tttcggtgta catcgaaatc
    13021 aatcttttta tatcatttta ataaaaaact ttagtgtagt ttcttataat tacctccata
    13081 gatcgctaaa cagacttgct ttacgcttaa tgtaataatt aacctaagtc tgaagtaaaa
    13141 tcataagaca gcagaaacta ctgtcttata atttagttta agcatgttac ggtaccgcta
    13201 ccccacattg caattattat tttttatcgt gaatgccaaa tatcttcgtt atactgctca
    13261 atggtacggt cagatgagaa gaatccagct tttgcgatgt tatggaccac ttttgtcatc
    13321 cataaatctt ggtcttcata gtctgctaac attttttctt tcacttcaat gtactcttca
    13381 aggtcaatca aagtcatgaa ccagtctttt gaaatcaatt ctttataaag acgatcaaga
    13441 cgttcttcgt tgccaaatgc tagcaattct ggactgataa taaagttcac tgctgcttta
    13501 atagcagggt ggttatcata gtaatctttt gctacataag aagcagtcgc ataaaggttg
    13561 atgatggtgt cagaatcttt accaaaggta tagatattct ccatgcctgc aagctcagcg
    13621 atttctacgt tagcaccgtc cattgtacca agtgttaaag caccgttaag catgaatttc
    13681 atattaccag ttccagaagc ttctttggat gctagtgaaa tttgctcaga aatatcagtt
    13741 gctggaatca agtgctctgc tactgtcacg ttgtaatttt caactagatg cacattaagg
    13801 tatgggctta cttcagggtc attgttaatc aattcagaca agcaaaggat caagtgaatg
    13861 atgtcttgcg caataatgta agcaggcgct gctttacctc caaagataac agtgatttta
    13921 cgttttggaa ggttgccttt tttaatttcc aaatatttgt gaatcacgta aagagcattc
    13981 atctgttgac gtttgtactc gtggaaacgt ttgatttggg tatcaataat agaatgttca
    14041 tcaagctcaa tgtctttatt gtctttaagg taacgtttaa gagctaattt gttgttgaat
    14101 ttgatttcag ccaatttagc atgaacagct ttgtcatctg caaaggccat caatttttct
    14161 aattttgttg cgtcagtcaa gtactcatcg ccaataagtt ctttaatgta atcagccaag
    14221 tcttggttag caaattctag ccaacgacgg aaagtaatcc cgttggtttt gttgttgaat
    14281 ttttctgggt aaaggtcata gaaagctttt aattcgctgt ttttcaagat ttctgtgtgg
    14341 agtgctgcta ccccattgac acttgttgca aaatgaatat ccatatgggc catgtgcaca
    14401 cgacctgatt cgtcaataat ttgaacagct ggatcagaca cttctgaacg aacaagagca
    14461 tccaattttt caatgatggt taccaagtgt ggcactactt cgtttaagta agcagttggc
    14521 catttttcaa gggcttctgc aagaatagtg tggttagtgt aaccaaccat atttttcaca
    14581 acagctaccg cttcatcaaa gtcaaagcca tgtttttcag tcaagagacg aattaattct
    14641 gggatgacca ttgatggatg cgtgtcatta atttgcacgt aagcgtagtc tgcaaggtca
    14701 tgaaggtttg aaccacgttc gatagcttca tcaatgatta attgcgctgc atttgacacc
    14761 ataaagtact gttggtaaat acggagcaat tccccatttt tgtcagaatc gtctgggtag
    14821 aggaacaagg tcaagttttt agcaatttgc gttttatcaa aagaaatgcc gtctttgatt
    14881 aacccgtaat caacgccctc gatatcaaac aagttaaggt agtttttagt gtcgcgtttg
    14941 taacccaaaa catcaatacg atcaagacga gatttcaagg tgaagttctt aaaaggcaca
    15001 tcgtaagaaa tgtctgttgg aaccaaccat gagtcatctt caatccagaa gtttggctca
    15061 gcttcttgct cattgtgttt gaagacttgc ttaaacaacc cacaatgata gtttaaacca
    15121 accccttcac cattaatccc aagagatgca atagagtcaa taaaacatga agcaaggcgt
    15181 cctaaaccac cattacctag tgatggttct aattcaacat cttcgacttc tgcgatagac
    15241 ttgccagcag ctgccaattc ttctttgatg tccttgtaaa ttcctaggtt aatcaggttg
    15301 tttgatagta atttaccaat caaaaactct gctgagatat agtaaacttt gcgtttagca
    15361 gaatttttag ccttgtggct agcttcttct ttgacaaagt ttaataatga tagataaatc
    15421 tcttcattgc tggcttgcgt aagtgatttt cctagtttag tttcaacata ttctgtaaag
    15481 cgtgtcatgt cttcctcttt tcaataatgt aacatttaaa tattatcttg cgcgaccata
    15541 aagatctgtt aaataaataa ggtaatcttt gtgatcttgg ttcaattcac cgtcaagcat
    15601 acgccattgc caattacctc caattgtatt tggcatattc atacgactct taccatcttt
    15661 atctaataaa tcttggatgc aaagaatggc tgtatcacaa acagaagcaa agattgttct
    15721 tagcatggct tttgtaatac tttcatctgc atgtttgtga agatagttat ttacaaagtg
    15781 tacttgttct tcactaagat tgtcatacca tccgttaacc acctcgttat catgagtccc
    15841 tgtgtaagcg acacaattac ggtcatagta atgtggtaaa tctatacttt gactcgttat
    15901 atcaaataaa ccaaattcta atatcttcat gccaggaaag cctgttgatg ctaatagctg
    15961 ctctgctttt tcatcaatat aacccaggtt ttctgcgatg atagggagct ctcctaaggc
    16021 ctcacgaacc gcagaaaata atgctatacc tggggctgag gcccaatggc catttctagc
    16081 agttttatca ccagcaggaa tttcccaaaa atctgagaag cctttaaaat gatcgattct
    16141 tagctgatca tatagtttga aactttcttg aatacgataa atccaccatg caaaattaga
    16201 cttttcatga gcagaccaat tgtaggttgg atttccccac agctgaccat cttcactaaa
    16261 gccatctgct ggtacacctg caataaacaa tggcttttta tcactatcta ctttaaatag
    16321 ctcaggcatc gtccaaactt ctacactgtc cgcagaaaca taaataggca tatcaccaat
    16381 aatttctatc cctttatggt tagcgtaagt tttcaaggct gaccattgtt ggtaaaagaa
    16441 gtattgacag actttatgat aggtaatctt ttttgcaagt aactcacggt aattattaag
    16501 tgagtcttct tggcgtttaa tgacagtttc gtcgtcccaa tcttgtaagg ctttattgtt
    16561 aaaatattct tttaaagcca taaattcagc aaaatcagtt aaccagctag aagctgtttc
    16621 aaaagcttct aatttacaca cattttcttg ttcagcaaca aaagctctca ctgctttttc
    16681 taaaagtgga cgtctaactt gaaaaagctg agcatagtct actgcttcag gatttgtgcc
    16741 gaatgtaata tcacacaaat ctgctgcttc taaaagttca tcatctacta gcaattcaaa
    16801 atcaatgaaa tgtgtgttcc cagcaatagc tgaaaatgac tgataaggag aatctccaaa
    16861 actcgtcgtt gttaaaggca gaatttgcca ataggtttgt ttcgtctctg ctagaaaatc
    16921 aacaaattca aaagctgatt ttccaaaagt gcctatccca aatttcccag gcagggaact
    16981 aatatgcatt aagataccgc ttgcacgttt gttcatgatt tttctccttg tgaaatctat
    17041 tcatgatgag attataacgc aagcgcttgc gtaagtcaac cagtttccta aaaaaagtaa
    17101 cattccttaa aaatgctact ttttttgttc ttaatgacta atatcacgga cgctttctct
    17161 ttgttttaaa ctaaaaggaa caaaaatagt ctgactaaga ttctgttcat tggaattgat
    17221 aatatcaagt aattgcttaa aagacatttt tccaagattt tcaacattta tatcaaatgt
    17281 cgttaaataa gggtgaatta atttagcgta attagaatta ttaaaagtga taattgacat
    17341 atcatctggc acttttatat cataaaaaga taataactgt accatacgaa tagccagaac
    17401 atcaccaaca acaaccaagg cagttgcttt aaaggaagat atagtttcca tcaatatttc
    17461 tacgctaaca ggatccttac gatcaaataa cagcattggc tttgttttta aagatcgctt
    17521 aaaacaaccc ttcaaatagc caagataacg ctcagaagtt acttctgata gtaaatcatc
    17581 tgttataaat aatatgttgt gatggccttt ttgataaagg tgttctactg ctgttttagc
    17641 cattagctga ttatcattat caatataagt ggttttatta gtgtcacctt gtggagcacc
    17701 tacaatgaca aatggtaagt tatttgtcat caaatatttt ttgacaggat catcttgatc
    17761 agaataaaga ataataaaac catcaactcg tttttgaaga tgcatcagtt tcacttgctc
    17821 tatcaggtca tcaagagata tacctgtagc aatcgacaca gtaaaatgag attctttagc
    17881 ttcgttagta atagtcgaca aaatttccat aaagaaaggt tcacttaatc tatcgctagt
    17941 tgtaatagga ggaaaaacaa gtcctatatt gtgtgtcaaa ccactcgcta gaatctgtgc
    18001 tgcgacattt ggaacatatc ccaaatctgc catcgctttt ctaaccttct cttttgtctt
    18061 catagaaata gatcgattat cttttaatac cctactcacc gtcgaagggt taacacctgc
    18121 cttttgagcg acatctttta ttgttaccat attaacctcg ttactatatt taccaaagat
    18181 aaaccttatc atgggtttgt catgtatttc gtttccatta tacaattatc tttcaaaaaa
    18241 tcaacttcaa tcaagattcc cttgtcattt taactcaaat tctctaaact atttttttaa
    18301 aaaaaacgac ctttttttta aaaaaaggct tgactttttc tgcaagcggt tgcataatat
    18361 taagtgtaag aaatatatct taggaggaaa tagctatgaa atcatggcaa aaagttatcg
    18421 tcggcggagc aagtttgaca cttgcaagta ccttgttagt gggatgtgga tcaggttcaa
    18481 aagataaaaa ggaagctggc gctgactcaa agactattaa actttgggta ccgactggct
    18541 ctaaaaaatc atatgcagat accattgcaa aatttgaaaa agattctggt tacaccgtta
    18601 aagtggttga atcagaagat ccaaaagcac aagaaaaaat caaaaaagat gcctcaactg
    18661 ctgccgatgt cttttcactt cctcatgatc aacttggtca acttgtagaa tctggtacta
    18721 ttcaagaagt tccagaaaag tacaataaag aaattgctgc tacttctact gatcaggcgc
    18781 tcgtcggtgc acagtacaaa gggaaaacat atgctttccc atttggtatt gaatcacaag
    18841 ttcttttcta caataaatca aaattagctg ctgaagacgt tacttcatat gatacaatta
    18901 ctacaaaagc aacttttggt ggtaccttta aacaagctaa cacttacgct actggtccat
    18961 tattcatgtc agttggtaac actttatttg gggaaaacgg tgaagatgta aaaggtacta
    19021 actggggcaa tgaaaaaggc gctgctgttc ttaaatggat cgcagaccaa gcttcaaata
    19081 aaggttttgt tagcttagat gctaacaacg ttatgtctaa atttggtgac ggttcagtag
    19141 cttcctttga atcaggaccg tgggactatg aagctgctca aaaagctatc ggtaaagaaa
    19201 accttggtgt tgctatttat ccaaaagtaa ctattggagg cgaaacggtt caacaaaaag
    19261 cattcttggg tgtaaaactt tacgcagtca accaagcacc agctaaaggt gatacaaaac
    19321 gtatcgcagc tagctacaaa ttggcatcct acttgactaa tgctgaaagc caagaaaacc
    19381 aattcaaaac tcgtaacatt gtcccagcca acaaagaagt tcaatcttca gaagctgttc
    19441 aatcaaacga acttgctaaa accgttatca ctatgggttc ttcttcagac tacactgtcg
    19501 taatgccaaa acttagccaa atgggcacat tctggactga aagtgctgct attcttagtg
    19561 atgccttcaa cggtaaaatc aaagaaaacg actaccttac taagttgcaa caattcgaca
    19621 aagatatcgc tgcaacaaaa taatatgatc tcatgtcatc actgctatac taaaacaagc
    19681 acaaggtaag tacttctaaa aagttctttc cacttacctt atgaagagtg gaactaggct
    19741 ccatcacatt ttattcaagc ttagtctcac tcttacttgt ttttgtttta ctagtagctt
    19801 agtgctactt aaatttttaa ctctttaaaa gtttacgtaa cacttagcta tttcatccta
    19861 acaagagatt gaatctgaac taccactcta gtatcctaaa ataaaggaga atctatatga
    19921 ctcagtcaaa cttgacacca aatatatctg taatagaagc cttaaaaaga ggcagttggg
    19981 atattaaact ttcgagtatt atcatgggat ttgccaactt tgctaacaaa cagtttatca
    20041 aaggaatctt atttttaata agtgaactta tctttctagt agcttttgtc tcccaaatca
    20101 tccctgctat ccgtggcctt gtcactcttg gtactcaaac tcagggaatg actacaaaaa
    20161 ctattgatgg gattaacatc caagttgctg ttgatggcga taactctatg ttaatgctta
    20221 tttttggttt agcatcactc attttctgcc tagtctttgc ttacatttac tggtgtaatc
    20281 tcaaaagtgc tcgtaacctt tatcttttca aacaaaaagg tcagaagata ccaagcttca
    20341 aagaagatct tgccacactt acaaatggtc gctttcatat gactttaatg gctatcccac
    20401 tgattggtgt gcttttattc accattcttc ctttgattta catgatctgt ttggccttta
    20461 ccaattttga tcataatcac ttgcctccaa aatctttatt tgattgggtg ggacttgcta
    20521 actttggaaa tgttttaagc ggccgtatgg caggaacctt ttttcctatc ttctcatgga
    20581 ctttgatttg ggctgttttt gccacagtaa ctaatttctt ctttggtatt attcttgctt
    20641 tgttaatcaa taccaaagga ttaaagtgga aaaaaatgtg gcgaaccatc tttgttatca
    20701 ccattgcagt tccacaattc atctcattat tgattatgcg gaacttactc aatgacgaag
    20761 gcccactaaa tgctcttctc aataaaatcg gcttgattaa tggctcactg ccatttttat
    20821 ctgatcctct ttgggcaaaa ttctcaatca tttttgtcaa catgtggatc ggtattccat
    20881 ttaccatgct gattgcgact ggtattatca tgaaccttcc aagtgaacaa attgaggctg
    20941 ctgaaattga tggcgctagc aaattccaag tcttcaagtc tatcacgttc cctcaaattc
    21001 tcttgatcat gacaccaaac ttgattcaac aatttatcgg aaatatcaat aactttaacg
    21061 tcatttacct ccttactggt ggtggtccaa caaattcaga atactatcag gcaggaacaa
    21121 cagacttgct ggtcacttgg ctttataaat taaccgtcac agctgctgac tacaatttag
    21181 cttctgttat cggtatctta atctttacag tttcagctat ctttagctta cttgcttata
    21241 caaggacagc atcctacaag gaaggagcgg ctaaataatg aaaaacaaac gtcgatttca
    21301 acttggactt gtttatgcta ctttaatcat cctctcaatc atttggctct tcccaatcgc
    21361 ttgggttatt cttactagct tccgtagcga aggaactgct tacgtcaatt attttattcc
    21421 taagactttt acattaaatc actacattaa tctttttact aatgaaacct ttccttttgg
    21481 aaaatggttt atgaatactc ttattgtagc cacttttaca tgtattattt caaccttcat
    21541 aactgttgcc atagcctact ctcttagccg aattaagttt aagtttcgca atggcttttt
    21601 aaaactagcc cttattttaa atatgttccc tggtttcatg agcatgattg ccatctacta
    21661 tatcttaaag gccttaggtt tgacgcaaac cctaacagca cttgtccttg tttattcctc
    21721 aggtgcagcc cttggttttt acattgcaaa aggatttttt gataccattc cttattcact
    21781 tgatgaatca gctatgattg atggcgctac tcgtatggat attttcttta aaataaccct
    21841 tcctttagca aaaccaatca ttgtctatac tgcccttctt gcttttatgg ggccttggat
    21901 tgactttatc tttgcacaag ttattttagg tgatgctaca agtaaatata ccgttgctat
    21961 tggactattt tcaatgcttc agccagatac cattaacaac tggtttatgg ccttcactgc
    22021 tggttctgtc ttaattgccg tcccaatcac tctcctcttc atgtttatgc aaaaatacta
    22081 tgttgaaggc atcacaggtg gttctgttaa ataagttaca acataccaaa ccttctaagg
    22141 gcaagccctt taggaggttt ttgataaata aggccgtaga taatcatatt agtcctcaca
    22201 tttatcttca gatcagccaa atgtattaat gattccttga cttttaccat gaattcggat
    22261 ataacaaaat gatgacatct aaaattacca ttaaagatat tgcacgagaa gccggggttt
    22321 ctgtggcgac cgtatcttac gtgttaaacc agcgcaatga tcaaaaaatc agcgaagaaa
    22381 cccgcaataa agtgctacat attagtaacc ttcttaacta tacacctaat caggcagcca
    22441 ggtcattagt cacacaacaa tcaaacagtg ttgtcctgta ttacaaatat gcagatagca
    22501 ttttagctag ggctgaacaa ctgcatacca ttagctttct atcccgccta ttgcatgagc
    22561 aggactatca gctggtttgc ctaaatgaag atagcactga aaaatttgac tgggcagacc
    22621 ttattctgac cttggacgtt gataatgata ccttttacaa aattggaaag cttaatttca
    22681 aacccttaat tgccattgat agctttgtta atgatcccct cttctttcaa attaatacag
    22741 attatgctgc tctcaaagat caggctaatc agttttttaa ggatgaacct tataccctgc
    22801 tttccttgcc tatcactaat cgtgagcgat atgagcatgt ttctgccttc tttccaagtt
    22861 tgcacattgt aaacgaccta agagagctaa cctactttga aaaggaaaat cttttactca
    22921 ttgatgagag tttggatcaa ttctttgtga actcttcgca aaaactctgc tgcccacgtt
    22981 tttcccccaa aaaagggcaa gttatcttag agaccatcga atgggccaaa aaacgccagc
    23041 ctgataaaaa acataacctt ctggtgtaac gcctgagaat taacctatct tgactaattc
    23101 cttgtaactc aaaaccttgc ctctttagat aaagaagcaa ggttttttga tgtctaatct
    23161 aataacaggg cctgacttgt ctcatcaatc tctaaactgt gttttgtaga acacccaggt
    23221 cagcattaat aaggtaccaa atacttggca attcataatc agtactggat cctgaataaa
    23281 gaaactaaga gcaatcgcca gtagactcgg ccaagccaaa caattaacca tcaatccaag
    23341 tccttcagag aagtttcgaa tcataaatag tcgtgatcgt ttagtcagag tcaaaaagaa
    23401 agcgcctaga ccaatcacaa taagggtacc cacacacacc atgagaacaa acgtcagcaa
    23461 aagaaaacca agtacactgg ctttattact gtcataccat tgctgattga caaagtcctt
    23521 cactgcttta actgttgtca ggtcagcgag tgactgctgc tggcctctaa cgtgagcacg
    23581 gagttccttg ccatcagggg taacaaaacg ccattctttt tttgtcacaa taatttgtct
    23641 ggttgattct gatgccaatt gctctaaatc gacctttgtc ggtaaaacag ccaaaaccaa
    23701 ttcaccatct cgtcgaatca gagattgacc ctgaaacgta tctttctcaa tctttccttg
    23761 ggtcaatgct tgataggttt tgtctgtgat aggcgacaaa ctcttagtta caatccgttc
    23821 caagggatac gttgtcatgt tagcatagtg taacgtaact ggaatcatta ttaaggcgtt
    23881 caaaaaaaca ataataagaa gattttgcca ccaagtaaac tgagctcggc tggcaaacat
    23941 tgccctagga gaaaggcaat gtgaaatgta agaaatagga aattgttttt tatctggcat
    24001 taaacattac tccttgtcag gttacccttt ggtaccacca cttgttaaac cggaaacgaa
    24061 atttttctgt aggaagaaaa agagaactga aataggcact gcaatcagaa tagctcccgc
    24121 agcaaataag gttaccttgg gatttctagc atcattcgta ataaacgatt gaagaccaac
    24181 tgctaccgta taattttctt gcgcccttaa aaggaattta gccaacatga agtctccgaa
    24241 aggacccata aaagcccata aggattgtac tgcaatcatt ggtcgcacaa gaggaaggac
    24301 aatttggtag aaggtcctaa agtgtccaga accatctaac ttagcagatt cgtccaagtc
    24361 ataaggtacc gtgtcaaaat aacccttcat caaccaggca ttcataggaa taccaccacc
    24421 gacgtaaatc aaaatcaaga accagtattg gtttaaggca ttaaagagcc acgccataac
    24481 aaagtaagcc gttaaagccg ccatggtagg aaccatctgt acgactagga aaaagattaa
    24541 actttttttg cgtccaaaga aattgtaacg gctatacgca taacctgtca aagtgatgac
    24601 tgttacttgt atgagcatgg tgaagaatgc cacgatcaag gtattccaat accatcttaa
    24661 gtataaggta tcttgaaaga gtgttttaaa gttagacaag gtccatggcc catcaaaatg
    24721 aaaactaaag gctgtggtat ttcctggtct aaaagctgaa ctgaccgtca ctagtattgg
    24781 gaataaaatc acgatcacta aggagattag atagagataa gtcaataatt gggtgaagaa
    24841 acgtttgcgt ttcatggata ttgaaacata ggtctttctc atgatctctc ctccatatca
    24901 aaagctttaa atttcttaaa ggtaatcaac gataccgaaa tcactattac agagatgatt
    24961 aaggtcactg ccgacgccat cgaaaactga ggcgaggttt gtgtggtcaa cttgtaaatc
    25021 caagaaatca gaatatcagt tgtcccagct ccgcccccca cagtaccagg gcccccatta
    25081 ttaaacagat aaataataga gaaattattg aagttaaagg tgtactgaga gataaaggtt
    25141 ggtgctgcaa ccgcaaaaat cattggcatg gtgatatggc ggaatttctg taagactgtc
    25201 gcaccatcaa cggttgctgc ttcgtataaa tcagctggaa ttgcctgtaa aatacctgat
    25261 accaaaatat agatataggg aaatcctagc caaccttgca ccataataac agccactttt
    25321 gtccagaagg ggtctgtctt ccaggacaca attccgaagt caacgaaagg aaggaatttc
    25381 tcgatgaaag gaagaacctg aacattcatg gccccaatgg aatcattaaa gaaattacca
    25441 aaactcataa tagagataaa tgctggaaca gcccatggta acaagaatat cacaccaaag
    25501 agacgttttc ctctgataaa ggattgatta gcaataacag ccgttgcaat tccaataaca
    25561 atttgaagac ttgtcgctgc taatgtccag atcagcgtcc atgacaaaac agatgtaaat
    25621 gctgttttga aggtgcttaa ttctaagata ttaagaaaat tcttcaaccc tacccaatcc
    25681 aataaacgat acggaggaat atgcctaaaa tcgtaattgg taaaagcaat cagcaaggtc
    25741 actaaaactg gaaaaataat agcgaaagcc attgctaaat aagccggaat gatgagcaag
    25801 taaggaaatc ctttttcata aatcgcttca agggtctctt tagccgtcac cggaaccttc
    25861 ttgccttcat tcatttgatg tgcaactaat ttagcatctc tcatagcaac caaatgaaaa
    25921 ataccaaata agactagagt aattaattgc atggccccct taattaacat aaataaggag
    25981 tgatcttgca ttggaacact tccaagactg taaagacctg ttaaagcagg aattcctaga
    26041 actacaattt ctagtagctc taggaagaaa acaactaata agactccccc tttaacgatt
    26101 tgtttattgt atagttgtcc caaacctggg ataacagata gccacatggc tttattaggc
    26161 ttctgttgtc tttggttctc taccattttt tattcctctt ctcataaatg atttaaggtt
    26221 atcctcctta tcatactaac ttccttttaa gctgactaat ttattttttt atagtaatgg
    26281 tttgtgcttc atgacctgtc tttatactat aagtctcagg acttgtccat aaaacattcc
    26341 caatactatc ttttttaaca agtttgactg ctatttcttt attgattggt agatgagtat
    26401 caaagaacca gtttgggtac ttggcaatgg tctgagtgtt attaaataga ggaccaacag
    26461 cattcttagc gtcatttgcc cccatctcaa aaacatcacc catgagatat agttgttccc
    26521 ctggtactgt cttaaaatca ttgatgagta aacgaacagg aatttgttta tcagtcaata
    26581 cttcaaaggc ttggtaacta ttgctggttt gcttatcggc agttgtcact gaaatgttat
    26641 aataatttgc tggaaccgtc ggtactttta aggtgataag ggtatctgac caagaaagga
    26701 tctcagcaga gatttctcca aaagtcactt gacctttaga attaccaaaa ccttgacctg
    26761 aaatagtaat cttatttcca gcaataccca ctgaagcatc gacatctcca agttgtggtg
    26821 tcttgtcctc tccttcataa gtccatacag cgacttgccc cgctccaagt tcaaagctac
    26881 taatagtgcc atctgctcca actattaatt cttgaccgcc aagaagacct tctaatttgt
    26941 ccttgtagct attttggggc aaggctgttt tagcattagt aattgtataa ccattcgttt
    27001 gatctctatt aatagccact agtgcgacat gattaccaaa tttacgctca aataccaaaa
    27061 catgatcact aatccaacgt tgttcagttg ttccataagc taaagcttga ttttgttttc
    27121 ttaaaggagc tagcttacta atcactttat aggcttgtga ctctttatta aaacttggca
    27181 tatcaccacg attattagga tctttatcac ctgttgcata ctgctctgta ccataataaa
    27241 tattaggcac acctctagat gttaaaagca aagcataggc ttgattaaca gcagtttgat
    27301 tattagccac ttttgttgcg aagcgttcca tatcatgatt atcaataaag gtcacctggt
    27361 ctgtcacttc attagtcacc tgatctctat tttcaagaac cttgtaaaaa tctcgcatgg
    27421 taaacgttga aaaacctgta tacaactgtc taatagcatt ggcaaatcta aaatctaaaa
    27481 gccccatccc actattgtta gcaaatgtcg tcatatcata atcatcgtcg gtatgtcccg
    27541 agaaccattc cccgaaaaca aagacattat gtttttcata gatatgactc aaccaatttt
    27601 tttgccaacc ttgtgacata tgtttaacag cgtcaactcg gataccatca acacccaggt
    27661 ctaaccattt atcaatagct tctttcatgt actggtcaac tttcggatta atgttattta
    27721 aatcagctag tccgtacatt gaatgataaa tagaattttc ataagtacta aaatcggtcc
    27781 aagattcatg attaaaaatc ttgtctttat catctgaaaa tttaccaact aatttaccgt
    27841 ttttatataa agcgccatct tctttgaaag ttgtgccttc tttttcggct gtagacgtat
    27901 gattaggagc aaaatcaata actaccttaa tatggtgttg atgagctact ttgactagtt
    27961 gttgaaagtc tgcttcagtg ccaaaatgct ggtttgtttt aaagaagtcc ttagcccaat
    28021 acccatgata tgcagcactt ccattagaag gatcaatact gtcgatattt tcaacaggag
    28081 aagaaatcca aatggcagaa atccccatat ctgtcaggta accatcctta atcttggcga
    28141 tgattccttg ccaatcacct ccatggtatt ttttaaggtc atttttatca aaaacatcag
    28201 tcttaccatt attagaggta ttaccatcgt taaaacgatc tgttacaatc tgataaatcg
    28261 tatctgttga aaaatctgct ttgttggtga cagaagcatt atcggcagca gaaacagtta
    28321 gtggaaatga aattaagcca agtaaaacag cacttttcgt taataactta taagttttga
    28381 tatgtaattc tctcatcgct ttttcctttt aaaataacct tttagttact aaacacaata
    28441 tatccatcct ggagtaattg ttttttgttt ttagttaccc cattgcttgt caaaatctgt
    28501 cctccttcct taatagaata agcactctca ccattgttaa gaacaagtga aatgctttgc
    28561 tcacctaagc tgcgtttcag aatgaggcag tcttcgtcat aatcaatgct aatagctcct
    28621 tcttgaagag ctggctgttg gcgaagagca ataatcgctt ttactttgct aaagaaatcc
    28681 ttgtcccgct cagcatcatc ccaaggaaaa ccgcgacgcg aatcagggtc gtaaccccct
    28741 tccattgcca cttctgtccc ataatacaag caaggaatgc ccataaagat aaagagcaat
    28801 gctaaagcag ctaacaattt atctttggaa cccttaactt gagtgaagaa acgatgcgta
    28861 tcatgagaat ccaaaagatt caagttcatg cgattgactt gccaagtgtt tcgcatcaaa
    28921 atgttgctta atttctcagc caattgtttt gatgtcatgg tttcaaaagc aaagtaatcc
    28981 aaacaggctt tggtgaaagc ataattcatt atcccatcat actgatcccc tgccaaataa
    29041 ggataggcat catgccagtt ctccccaatt aaaatggcat ctgctttttc cgctttaacc
    29101 gcctgacgga aacgtcgcca aaaatcatga gatacttcat cagaaacatc taggcgccaa
    29161 ccatcgatac aaaattcttt aatccagtat cgcccaatct caatcagata gtcttgcacg
    29221 tctctatttg aggtattcca tttgggcata tagttacatc cagcaaaggt ttcatagttt
    29281 actaggtcca tggatgggtg ttcatcatga gtcataaacc aatcaaaaaa cttagactct
    29341 ttaccgtatc tcaagacatc ctgaaattcc acggcatcac tgctggcatg gttaaagaca
    29401 gcgtctagaa taatcttgat tcccattttg tgagctaaat caatcaattc ttgcaaatca
    29461 tatttagttc caaattgtgg atcaatagcg tagtaatcac taatatcata tttgtgatta
    29521 ctaatggatt gaaaaattgg cgttaaatag atgacagtaa tccctaaatc tttgaggtaa
    29581 tctaattttt ctgtaattcc ctttaaatct ccaccagcaa aacttttagg agtcggtttt
    29641 tctaaccaac ccatgttgac ataactgtca cctttttccc aatccccacg gttaaagcga
    29701 tcaacaaaga tttgataaaa aaccgcgtct tttgtccaag gaatgacttg atgaacatca
    29761 acagcattga tataaggcat ttggaagaaa ttataaaacc catttgaaaa atcgtaacta
    29821 gtagttaacc catcttcact aaaataatag gtttgacctt cttcttcaat tttaaaaatg
    29881 taggccaacc tcacatcgtc taatgttaaa gtagtttcat aataagcatg cgtatggtct
    29941 gtataggcaa ctgacatttc caattcttct tggaattcat gataaccata tttaggcccg
    30001 tggaccaaat taacagtaat acctctatct tctttggcca cgcgtaatcg gatgacaagt
    30061 tccttttgag atatggcaaa gcaatacctc gaatcaggaa tatggagcat tccggcaaca
    30121 ttcatttcta cctccattaa taaagtattg acgattactt ctttttcttt aaaacgaaaa
    30181 aatagcagag cgactcatac ttctatattt ttagtatctg tttcatcttc atcaaactaa
    30241 cagaaataga agctgggcgt acttctttat cccagcctcc cttctttgcc ttattcagcg
    30301 tatttttgtt caatagcttc cttaatagtt tttgctgctt cttttgcagc tttagatgct
    30361 tcttccttac cagaagccac gttaaagaac atatttgcac ctggttccca aacttcagcc
    30421 atttctggaa tatttggcat tggttgtgcg ctctcaaact gactaatcac agctttcgtt
    30481 aactcattac cctctttaga agcatagtta cgtgctgtta agttagctgg aatttcttgt
    30541 gttttatcat agaaacgttt ttggttttca gcattggtca cataatcaag gaatttttga
    30601 gcagtcgttt ttcctttaga atagtttgaa ataacccaag ctttaccacc tgcgaacggt
    30661 tggtattttt taccatttgt caaagtagga atttccatta ccccaaagtt aacaccagca
    30721 tctttaaagg agctagctgc ccatggacca tcaataatga caccagcttt tttagaaata
    30781 aattgttcag tgataaaatc accagctttt ttagtgtctt gcattccttg aggccaagtg
    30841 ccataccact gtttcgcgta gtttaaccct tcaacagttc cgtcgttacc taggcctaaa
    30901 tcacttggtt tggttccttt atcaccaaag atataaccgc cataaccggc aattaaacca
    30961 taaccataat agaagtctgt ccatttcgcc aagaaaccta cagattttcc tggttcagag
    31021 gcaaaagcaa acttagaatc tttttgtaag acttctaatt cagtaaagct tttaggtgct
    31081 tgaggcacta aatccttatt ataataagtt accaaagttt caattacgtc tggtgcacca
    31141 taagttttac catcaatggt tactaatttc ttaaccgtat catcaaactc tttgctgttt
    31201 cctaaagtaa cctcagcgat ttgaccttca gttcctaagc cacctacacg gtcaaaaggt
    31261 gctaaaaaga catctggtga agctcctgtt ggaccatccg ttgatagctt atcaagagta
    31321 tccatcatac cttctttttt gactttaacg gtgactttat gttctttttc aaactcaccc
    31381 ttaatactct taatgtaatc aacatatccc tcatcaacag agactacaat agtctttccg
    31441 tctgtttcct taacgccttt accaccacca cttacgcaag cagttagggg tagcactgaa
    31501 gctaaggata aagttccaag cacagatgtt tttttccaat tccatgacat aacatgttcc
    31561 tcccgaaatg gttttttctt aaacacaaat caaatcatct atctactctc atcatattag
    31621 caaataaaag ataacataag gcatttaaaa ttaataacag taatagtttc gaaacttaaa
    31681 cgtttaagtt aagtttatcg taatcgcttt catttgtcaa taactttttt acttttcttt
    31741 tcttttaaga tcatatcagt agttttcctg ctaattgaaa acaaggcatt tactgtcaca
    31801 caagtctgtc ctttcttttt ttctacaact ttatttcgtc agcgtaaata aaacaaaagc
    31861 tctataatct cttgaatggg taaatccact gtagagatta tagagctttt tgaatatcaa
    31921 aaaagtccca taagatttat aatgaaaagc aaccaaactc tcattagaaa gactcttatg
    31981 gaacatatca atcatacctt acaacacatc ggaattaaag acaaaaatat cactctaaac
    32041 aatgttttga aggatgaatc tcctactgag ctcgttacta cttatcagaa aggtagatag
    32101 gaaatcctga tgaagagtgt gtccaaggga ttatcaatta ggtcttagat tacaaaatag
    32161 taattcaggt atgctctact gttttcaaca ctagttctgc aatttgtttt cgagcttgct
    32221 tagcttctct tattggaaaa ataacatacg catgaatcat tttttctgca ataatcagct
    32281 gattagcaat tcgttgtctt gttaattgat catgtaaaga cataatgtct gggtaaaaaa
    32341 tctcttttgt cccaacaaag gtcgttattt caggcaaatc ctcataatca ccatacaaag
    32401 gactgacata aggaagttgc atattacctt gaccacctgc ccatagttca cctatatcac
    32461 gaagacgacg agcatctagg taagcttctt ctgcttcaaa atccttgtag gcttgatttt
    32521 taaaactaac atctaaccaa ggagatataa gaattaattg ctttggctgg ggtgctgttt
    32581 tagtatctcg tatatactta gcaaacgcca aagccatacc cccaccagaa gaatcaccaa
    32641 tgacactaac ttgactcggt ccattagaca agcaaaattg ctggtaagct tcaactaatt
    32701 taggatagac atcttgataa gtagcatacg gtactttagg aaagttagga aaaacaacct
    32761 tggcattagt cagctgtata agatgcttaa ccgtcttaaa atgaagtttt tcgggtcgtc
    32821 gtaaatagac actgccataa agataataaa taacaggctg atgactttgc ttttgatcat
    32881 taatgataaa aacttgcatc ccgttcacat cgtattcttg agttgaaaaa cctactatct
    32941 cttcaggatt atctagatga taagggatat tacgattacg ctgcgtctca acccccttat
    33001 aattatcaac ttttttagat aacttatact ttctataagc aaacattttc tcaaccaacc
    33061 aacttgaaaa ggagcgcttt tgaccatatt caactatcaa aatacctagt atcactccaa
    33121 aaaaaatcac cacagcaata atgaccactt attatcctcg ttttctaata ttattttact
    33181 attgcaagtc tttcctattt gcccaaattt tactataaaa ataagggttc attttatagt
    33241 tgggcactgg ctgcttcgtt tctagaaatg gttgcacttt cttatcaaaa gctaaccagc
    33301 cattccaacc gagatggatg gtatcttgca taaagtagga ctcaccacca tcttttgaga
    33361 agtcagcaat gcgatgaaat ccttgtgact ttaactggaa ttttatttta cgaactgccg
    33421 cttgatactt atcttgattt aagccggtat aatccgccca agctttatta acaggagtta
    33481 taacaaagag tacatctgtt tttcgtttag caaattctga taataaaagc tgaaaatcat
    33541 tgtattctgg tgacgccagg taactataat taacttggaa attcttataa agattgtatt
    33601 taggtgctat tcgtttacga taaaatgtat ttttaatccc aaaacggttg ttggttgttg
    33661 ctaattggcc tctcttagtt gctaatgcat tcaattgttt atacgaaaat actttaggta
    33721 atcccttaac gcgaggcaaa attctttttt catagttagt agatttgcct aaaaaactaa
    33781 aaagggactc ttctctcaat gctacttgat gttgacattt caaaatagct ctgtctaacc
    33841 gactaagaga cttaccctta cttacttttt tcaataagtt tgatttagac acaccagggt
    33901 taagctcaag caaacgcttt gctgcaaact gtgattcttt atcagttcta gcttttagta
    33961 aaaattcaat cacttgagtg ttagacaagt acatctgaac cgcactagga ttaatccctt
    34021 gagcagtaaa ccattgagga gatactacaa agatggcttt tttcttttgc atttcattgg
    34081 taatttgttg cataccataa taatgcgaca aagatgctga tcctctctta ccaattaaaa
    34141 atggtctata gctccgcttg tagcgctctg caagcaccga agggtgcata ctatccattc
    34201 gactccattc gctagaacca aaaaaaggca caaaacgaca agtctcatct gataaagctt
    34261 gtcttttaat caaaccattt ttaaaagaac tatctgtgat cgcaacggca tttgcttttt
    34321 cctgagctat ggaatgatca agttgtgtag gaaaactaaa aatagtaatc actactaaaa
    34381 caaaggcaat aagaagagga cctagaatta accagagtct cttaagcatg ttgcaattcc
    34441 tctacacctt gaacaatctt agttactgtg ttccaatcat cacgaccaaa ttctgaaata
    34501 ggtactttaa tattgaacgt tgactctaac tcaacaatca attcgactgt cccaagacta
    34561 tccaacacac ctgcatcaaa caagtcttcg tccatcatct ctgaaacatc ttccataaac
    34621 aaacggtcaa acaattcaat tacagtttct tcaatagaca tttttatact tccttttatt
    34681 aatgtagtgg tctgttaaac caaaggtcat ttaaaaaacc agagaataac agaagtgaaa
    34741 acatgacaac gtggaaagtt accacgatac ataagacatg gaatgccctg ctttgaaaga
    34801 ggggtgataa gccttttttc ttacggtgac ggttgatttc ttttttctta cgaatccaag
    34861 catcattaat aataagtcct ataccatgga aaagcccata agcgatataa taccaggtta
    34921 agccatgcca aaatcccatg actagcatat taaccagata ggcaacacct gaagtgacat
    34981 ttcggttttt aaaggtttta tgcttaatca atagatgaac caatcgcata aacacataat
    35041 ctctaaacca gaaggacaaa ctcatgtgcc atctattcca aaaatctttc aaacttgcag
    35101 ataagaaagg catgttaaag ttttctggtg ttcgaatacc caataggtag gaaataccaa
    35161 tcgcaaacat cgaataacca gcaaagtcaa aaaagagatt caagccatat acgtacataa
    35221 ccagaatagt ttccttatta aagtagccac caaccatcaa agccttattt tcaaggagag
    35281 gaagtaagat gccacccaaa caataggaaa tgatatgctt gtatagaaaa cctaacatga
    35341 gatacatgac tgccttattg agcattgcaa aataatcatc acgttcagga agtttatgat
    35401 aatcttcctg aaaatgtctg aagcgatcaa tggggccact tgagaaggtg gggaagaaaa
    35461 tcatgaagcg aataaaatcc ggtaaacgaa cctcttggag agtcccgtca cgcatctcaa
    35521 taatcattcc aatactttta aaggtcaaat atgaaatccc tagaaaacta aagagtgttt
    35581 gagaagaagg acctgttagg ggagcaactt tgacccagat aagggggaat aaggccatcg
    35641 caatagctaa gtaaaacact cctgcactat tagcattctc acggtatttc tggtaagcaa
    35701 aaacactgat gatttgccac aaaagataaa agagaaaagc aactaattgt tgataatgat
    35761 ctcctccaaa cataaagaga ataaatacca aactcaccaa ggtttcataa gtgcttaagc
    35821 gcttttgttt aaaaatccca atgatgactg gtaagaaagc caaaataaga tagacaaagt
    35881 aaatggggtt accgtaaggt tccatgtagg gaatgtggct aaaaaacatc atcatcggtt
    35941 attgacctca ttaatcaaag ttttaatatc tatcttacca tttggagtta atggtagact
    36001 atctcgataa agaaacttag aaggcatcat ataactcatc atatgatcct taacagaggc
    36061 tttgatagct ttggttaact ccaattccct atcaaaacgc tctttaaccc catctttgac
    36121 aacgatatag gccaagagat tttgaacctt atgttcttta ttgtaccttg gaacagccac
    36181 agccgatgct accattggtg attgattcaa ctgttgggaa acatcttcta gttcaatacg
    36241 ataaccagca tatttaatct gaaaatccaa acgcccacca tacaacaaaa tattatcttc
    36301 tgtcagtgag ccaatgtccc ctgtatgata agcaggctgt cctttaaaag taaagaaagc
    36361 ttctgcggtt ttctcaggat tgttgaggta accttttgac acagcaggcc ctgtaacaat
    36421 aatttcaccc tgctcccctg aagataactc cttaccatct tcatcaataa tataggtcgg
    36481 agaatctggt ttggggtagc caatcggcaa gcgggtataa ttatccacca tttctctggt
    36541 aatttcaata gcggataagg ctacagtcgc ttctgttggt ccataggcat tgataatctt
    36601 ggcactcggg aaacgttcaa agagttttcg agccgtagaa acggttaatt cttcgccatc
    36661 aaaataaaaa tgcgttaaag ctggcatctt agcctggcaa aaatcatcgc taagcatggc
    36721 catatcagca aatgaaggag tcgatgtcca aatgccaact ggaagttgcg caatcgttgt
    36781 aaataactgt ttaaagtctg ccaccaattc ttttggaagt gcaaataagg ttccacctaa
    36841 agccaaggta ggtgcccagt acatgacaga aaggtcaaag gaatagggtg gctgcgccag
    36901 catttgtggc tgtttaggta catcaaatgc tgcatcttcg atcatccagt tggtaaagct
    36961 caaaagattg tcatgtgaaa tttgcacccc ttttggttgg cccgttgttc cagaggtgaa
    37021 aataatgtaa taattatcat ctcctttaac agaatgtgtt cgctcatagg gcatttctgc
    37081 taattttgct gactcaatct ctgatagtga gacaagggaa atcccttcaa tagtaagagg
    37141 gaattcctca atagcaatga ttaaactggg ctttgcaatc tcaataatcg ctaaaatacg
    37201 ttctggtgct gaatgcacat ctactgggat ataggcatga ccagatttgg ttaaagctac
    37261 aaaagtagct aacatatcat aagtttgcgc cccaaaaacc aaaactggag attttgccag
    37321 taaagctaag ctatctataa atgcagcaat gctatcagaa tctcttttga gttgtccgta
    37381 agtgcggcgt tcccctaaac aatcataaac tggaaaatca gcctgtgtct gagcaaactg
    37441 ctcaatactg tcaatcatat ccttaatcat cagtcaatct cctaaaattc attataaata
    37501 aagttacttt gaccatgtcc tagataacca aagaaataga ccagcaacat taaaatcaga
    37561 taaaataaaa ttgtcttgcc aataaaaaca gcaattcctc tcattcttga tttgtttttt
    37621 atcatacttt accttcttgt attagtgaaa taatgtccta aaaaattcta ctcgaaaaaa
    37681 cctaacttga caagctaaaa gtcatattat
//
LOCUS       DAUGQX010000018        35539 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUGQX010000018 DAUGQX010000000
VERSION     DAUGQX010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35539
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.018"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            236..1795
                     /locus_tag="VIA51_000814"
     CDS             236..1795
                     /locus_tag="VIA51_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEQ8682769.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSAAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKESHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            1892..4090
                     /gene="nrdD"
                     /locus_tag="VIA51_000815"
     CDS             1892..4090
                     /gene="nrdD"
                     /locus_tag="VIA51_000815"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEQ8682770.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEHEIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            4272..4418
                     /locus_tag="VIA51_000816"
     CDS             4272..4418
                     /locus_tag="VIA51_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682771.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            4447..5382
                     /locus_tag="VIA51_000817"
     CDS             4447..5382
                     /locus_tag="VIA51_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8682772.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTNLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            5391..5900
                     /locus_tag="VIA51_000818"
     CDS             5391..5900
                     /locus_tag="VIA51_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8682773.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSYAISKNITTILVTCDETNIASRAVIVANGGILEDSRGGTERY
                     WIEEQRGDK"
     gene            5900..6514
                     /gene="nrdG"
                     /locus_tag="VIA51_000819"
     CDS             5900..6514
                     /gene="nrdG"
                     /locus_tag="VIA51_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEQ8682774.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(6688..7419)
                     /gene="yaaA"
                     /locus_tag="VIA51_000820"
     CDS             complement(6688..7419)
                     /gene="yaaA"
                     /locus_tag="VIA51_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEQ8682775.1"
                     /translation="MLTFLIPTAKEMTIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEESAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(7461..8318)
                     /locus_tag="VIA51_000821"
     CDS             complement(7461..8318)
                     /locus_tag="VIA51_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8682776.1"
                     /translation="MIYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPGDKAYGLYHTAFLVPDRHSLGLVLNHFLTRSISLEGAAD
                     HGHSEAIYLSDPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKH
                     FLLAQDTRIRHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYYHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     RVNVILGQD"
     gene            8577..8843
                     /locus_tag="VIA51_000822"
     CDS             8577..8843
                     /locus_tag="VIA51_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8682777.1"
                     /translation="MLRDLLKGTLRFGQLKSSIGSVSQKVLTAQLRAMEADGLVHREV
                     YAEVPPRVEYSLTETGLSLAPVIEAMSDWGQTYQEKHADLFEEG"
     gene            complement(9122..9835)
                     /gene="treR"
                     /locus_tag="VIA51_000823"
     CDS             complement(9122..9835)
                     /gene="treR"
                     /locus_tag="VIA51_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEQ8682778.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            10046..12070
                     /gene="treP"
                     /locus_tag="VIA51_000824"
     CDS             10046..12070
                     /gene="treP"
                     /locus_tag="VIA51_000824"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEQ8682779.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKVVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSSIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSD
                     APVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDVFTVTVEGSLPRQIKVNDKLAVAVKK"
     gene            12137..13765
                     /gene="treC"
                     /locus_tag="VIA51_000825"
     CDS             12137..13765
                     /gene="treC"
                     /locus_tag="VIA51_000825"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEQ8682780.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLLGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFENLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILADN"
     gene            13973..15868
                     /gene="pepO"
                     /locus_tag="VIA51_000826"
     CDS             13973..15868
                     /gene="pepO"
                     /locus_tag="VIA51_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEQ8682781.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(16034..17074)
                     /locus_tag="VIA51_000827"
     CDS             complement(16034..17074)
                     /locus_tag="VIA51_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEQ8682782.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKADEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(17208..17975)
                     /gene="rpsB"
                     /locus_tag="VIA51_000828"
     CDS             complement(17208..17975)
                     /gene="rpsB"
                     /locus_tag="VIA51_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEQ8682783.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            18279..21353
                     /locus_tag="VIA51_000829"
     CDS             18279..21353
                     /locus_tag="VIA51_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8682784.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLVYINSQLGSQPVTAEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSASIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(21384..22370)
                     /locus_tag="VIA51_000830"
     CDS             complement(21384..22370)
                     /locus_tag="VIA51_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEQ8682785.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS"
     gene            complement(22556..24097)
                     /gene="hutH"
                     /locus_tag="VIA51_000831"
     CDS             complement(22556..24097)
                     /gene="hutH"
                     /locus_tag="VIA51_000831"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEQ8682786.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACHIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAVGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(24108..25451)
                     /locus_tag="VIA51_000832"
     CDS             complement(24108..25451)
                     /locus_tag="VIA51_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEQ8682787.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPLALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFESLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(25671..26267)
                     /locus_tag="VIA51_000833"
     CDS             complement(25671..26267)
                     /locus_tag="VIA51_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEQ8682788.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     TATVALRQTTFTRLDGYHRILMSLDKPITLSDLSHAKEISLAPFQPYAFEGDTRIVSR
                     GTCQDINLMYDDQYQGQLLPVWSDTPFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVTEQEASLSDLKVCLNQTSPAQTPVAVWAGLWYKT"
     gene            complement(26289..27962)
                     /locus_tag="VIA51_000834"
     CDS             complement(26289..27962)
                     /locus_tag="VIA51_000834"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8682789.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDAR
                     QLVALKNKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGIPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLT
                     KIVTKVYGGKGINLSSAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(27980..28606)
                     /locus_tag="VIA51_000835"
     CDS             complement(27980..28606)
                     /locus_tag="VIA51_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formiminotetrahydrofolate cyclodeaminase"
                     /protein_id="HEQ8682790.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQDIITEIHAKSTALQASLLAAIDKDTEAFNLVSAVFDMPKETDEDKA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(28617..29516)
                     /gene="ftcD"
                     /locus_tag="VIA51_000836"
     CDS             complement(28617..29516)
                     /gene="ftcD"
                     /locus_tag="VIA51_000836"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEQ8682791.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYHKQILENHLLG"
     gene            complement(29605..31635)
                     /locus_tag="VIA51_000837"
     CDS             complement(29605..31635)
                     /locus_tag="VIA51_000837"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEQ8682792.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFEEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRFRPKDRIYGKPIDEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIKTRHSQGWISQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGNHDDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            31927..33192
                     /locus_tag="VIA51_000838"
     CDS             31927..33192
                     /locus_tag="VIA51_000838"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEQ8682793.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGTQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(33250..34782)
                     /gene="ahpF"
                     /locus_tag="VIA51_000839"
     CDS             complement(33250..34782)
                     /gene="ahpF"
                     /locus_tag="VIA51_000839"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEQ8682794.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHGSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(34803..35363)
                     /gene="ahpC"
                     /locus_tag="VIA51_000840"
     CDS             complement(34803..35363)
                     /gene="ahpC"
                     /locus_tag="VIA51_000840"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEQ8682795.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
BASE COUNT        10189 a         6786 c         7872 g        10692 t
ORIGIN      
        1 agaaattgac taaataaaag attctgttat acttgtttta taatattctt tgacgataat
       61 atcatttttc aacttacttt gtttatgtac tgtcactttg ctatgtgcaa tacaaagtca
      121 tgttatttat ctcatactaa aaaataatgg ataatagcta tgttagacta gtgatatgaa
      181 gaaatattgc ttttattgaa tcgttagaga atatgatatt tcaaggagaa aaatagtgat
      241 cgagttaaac gatgaattca tccgaaaaga gacgatagaa ctggccaacg atggcccacg
      301 agtacacacc actcaatatg aaactaaagt acctcggctt cataaatgct atctgctttt
      361 ctttagcatt attatcagtt ctttaacaat tgcagtacct tttttaacag atgcagccaa
      421 tggtcttcag tcccaaaact tatatatagg aatgatgtta acgaaggggc aacttcccta
      481 tagtgctgct tttacaacag gagggctctt ttactttgtt atcattgcat taagttatta
      541 tttgggatcg acactttggc tagtctttgt tcaggtgttt tgtttttact tatctggttt
      601 atatctttat aaactcatta attatatgac aggctttcaa aaagtggctt taactttttc
      661 aattagctac tatttattat ctgttagtct tggttttggg ggattgtatc ctactcaact
      721 ggctatgcca tttatattaa tatcggcttg gtttttaact aagtattttg cctgtttagt
      781 gaaagatgag gcatttattc tttttggctt tgtaggtgct cttgcaatgc taattgaccc
      841 gagtaccctt atcttttggt cttttgcttg tgtgacagtt ttttcttata atataagcca
      901 aaagcatctt gcaagaggtt tttatcaact gctagcttcg atttttggaa tgattttagt
      961 tttttacaca gcaggatatt tcattttgaa cttacaagtg ctaaatcctt atttatcaca
     1021 aacgatgatt tatcctttta ctttttttaa atcaggaaac ttatcgttgc tttttggact
     1081 ggctattcag ttgttcttcg ctttggggct tggtcttttg acgggaatgg agaatgtcat
     1141 taggcgattt aaaaacaatt ctgatagggt cgtcaagtgg ctatttgtca tggtcattct
     1201 agaatctata cttgtggcta tattttcaca agactatcgc ccctatcatc ttttacctct
     1261 tttacctttt ggattaattt tgactgctat tcctgttggc tatcagtatg gtataggatt
     1321 aggtcagagt agtcatcgca gacgtcatgg taaaaatggt gttggtcgag taatgatgat
     1381 ttatcttaag agacactttt atttgccaat tttaattgta gggacaatac taatctgttc
     1441 tacttattgt ttcattagta gtattcctct taatcaggag cgtgatcata ttgctagtta
     1501 tttagaacag aaactaaata aaactcaatc tatttatgtt tgggatgata cttctaaaat
     1561 ttatttggac agtaaagcta aatctgtttc tcaatttagt tctcctgaca tcaatacgca
     1621 aaaagagagt catcgaaaaa tattagaaga tgaactatta gaaaataagg ctgcttatat
     1681 cgttgttaat cgctataaaa acctgcctaa aatcattcaa aaagtattat ctactaatta
     1741 caaagtagat aaacagataa cgacaaaaag ttttattgtt tatcagaaaa agtaatttaa
     1801 tatcaatata ttgtgttcga gcaaaaaact tgacacaata tattgatttt tttagttgtc
     1861 gtgatataat agttccgtaa ggagatttga tatggtaagt ttagaagaag acaaggtgac
     1921 tgttcaacct gatattaaag tgattaaacg agatggtcgc cttgttaatt ttgatagtac
     1981 aaaaatctat agtgctttat taaaagcaag catgaaagta actcggatgt cgccacttgt
     2041 tgaggctaaa ttagaggcta tttctgatcg cattatagca gaaattattg agcgttttcc
     2101 aactaatatc aaaatttatg aaatccaaaa tattgtagag cataagcttc ttgcagctaa
     2161 tgaatatgct attgcaaaag aatacattaa ttatcgtact cagcgtgact ttgcacgttc
     2221 acaagcaaca gatatcaatt tttctattga taaattaatt aataaagatc aaacagttgt
     2281 taatgaaaat gctaacaaag atagcgatgt ttttaatact caacgagatt taactgctgg
     2341 aatcgtaggg aaatcgattg gtttaaaaat gttaccttcg catgttgcta atgctcatca
     2401 aaaaggagat atccattacc atgatttgga ttacagtcct tatacaccga tgacgaactg
     2461 ctgtttaatt gactttaagg gcatgttagc caatggcttt aaaattggta atgctgaagt
     2521 ggaaagtccc aagtctattc aaactgcaac agctcagatc tcacagatta ttgcgaatgt
     2581 agcatcaagt cagtacggcg gatgcacagc tgatcgcatt gacgagtttt tagccccata
     2641 tgcggagctt aactttaaaa aacatatggc tgatgctaag aaatggatcg ttgagactaa
     2701 gagagaaagc tatgcttttg aaaagactca aaaagatatt tatgatgcga tgcagtcttt
     2761 ggagtatgaa attaatacgc tctttacgtc taatggtcaa acaccattta cttctttagg
     2821 atttggtttg gggacgtctt ggtttgaaca tgagattcaa aaagctattt tgaccattcg
     2881 gattaatggt cttggtagtg aacatcgcac ggctattttc cctaaattaa ttttcacggt
     2941 taaacgtggc ttgaatttag aaccagattc accaaactat gatattaaga ctttggcttt
     3001 agaatgtgcg actaagcgga tgtacccgga tatgttatct tatgataaaa ttattgattt
     3061 gacaggatct ttcaaatctc caatgggatg ccgctctttc cttcaaggct ggaaagatga
     3121 aaatgggcaa gatgtgacct caggccgtat gaatcttggg gttgtcaccc tcaatttacc
     3181 tcgcattgcc atggaatcaa atggcgatat ggataagttt tgggagctgt ttaatgagag
     3241 gatgctaatt agtaaggatg ctttaattta tcgtgtcgaa cgtgtcacag aagcaaaacc
     3301 agcaaatgct cctattcttt atcaatatgg tgcttttgga aagcgtttgg agaagacagg
     3361 gaatgtaaat gatctcttta agaatcgtcg tgcaacagtc tctcttggct atattggtct
     3421 ttatgaagtg gcgtctgttt tttatggtgg tcaatgggaa ggtaatccag atgctaaagc
     3481 ttttaccttg tcaattgtca aggcaatgaa acaggcctgt gaggattggt cagatgaata
     3541 tggttatcat ttctctgttt attcgactcc atcagaaagt ttgacagatc gcttttgtcg
     3601 tttagatacg gaaaaatttg gcattgtgac agatattacg gataaagaat actatacaaa
     3661 ttcttttcac tatgatgtgc gtaagagtcc gacacctttt gaaaaattag attttgaaaa
     3721 agattatcca gaagcaggtg cttcaggtgg ttttatccac tactgtgagt atcctgtttt
     3781 gcaacaaaat ccaaaggcct tggaagcggt ttgggactat gcttatgatc gtgtggggta
     3841 tttgggaacc aatacgccta ttgataaatg ctataattgc caatttgaag gcgattttac
     3901 cccaacagaa cgtggtttta cttgcccaaa ctgtggcaat aatgacccta aaacagttga
     3961 tgtggtcaaa cgtacatgtg gttacttggg gaatcctcag gcccgcccaa tggttaacgg
     4021 tcgccataag gaaatctctg cgcgtgtaaa acatatgaat ggttctacta taaaataccc
     4081 aggcctgtaa actcaagctg ggggagagcc cttttgatgg aaatatgata tgcttaaaag
     4141 gttgcttcat gcaagcaatc ttttattgtt taatggtttc ttagcaattg tgagataaga
     4201 ataactaatc caaaatgact aattagctgt tagcaatcgg actataagaa gaaagagata
     4261 aggaagaaat aatgggaaaa tatcaattag actataaagg aatgcagcag gtagaacgct
     4321 ttcatgagaa gcattctaaa aaaaagacgg ataaaaaatc ccgcgttcaa gaacttaagg
     4381 ctcggttttt agagaagtca aaaaaacagg ataactaaag tatccagtaa agaaagaagg
     4441 ttgagtatgc ttaatattgg gattgtggga ctaggtgcta tttcacaaaa agcctattta
     4501 ccatatatga gacagctgag tgacattact tggcatctat caacgcggaa tgcagcagta
     4561 cgtcagcagg tcggtcagtt atttggtcac gctattcttt acagtgatgt caaggagttg
     4621 tcaaaaacaa acttagatgg ggtctttatt catgcggcca catcggccca cgcagagttg
     4681 gctagtttat ttttaaatca ggggatccca gtctttatgg ataaacctat agctgacaat
     4741 tacctgatga caaagaacct ctatgactta gccaaagaaa atcagacttt tctgatggca
     4801 ggatttaaca ggcgttttac acctcgtgtc aagaagttgt caagtttgtc aactaagcgt
     4861 aaagtggctg ttgaaaaaaa tgacttgaac cggccaggag atatgacttt taagctcttt
     4921 gatttcttta tccatccttt agatacagcc ttattcttga cagaagggac cttactaaaa
     4981 gggcattttc aatatcatct ggaagcaggc ttactgagtc aagttatggt aaccttgatg
     5041 accgaaagca tgacgactac agcttctatg aatttacaat cagggagtcg ccgtgaggta
     5101 atggaagttc aacgggctga agaaacttat catttagaga acttagacga gttatctatt
     5161 tataaaggta ctgaaaaaag ggtgcttggc tttgcttctt gggacactac cttgcacaaa
     5221 agaggttttg aaacaatgat cgatgccttt ttagaagcta ttagcacagg cgtcaatcct
     5281 gtcagccctg agtctagtct tttaagccac tggatttgtc aacagattgc tgactctcag
     5341 ctttcttatg gagagttaac ggtagagttg cctaaggatt aggaattgat atggaaataa
     5401 gacgaccgac tttaaaagat aaagacgctg tattgtcaat gattaacgaa tttttagagc
     5461 agaaaagtgc tacagatggg ttatggcatt ttaacgtcaa tgactttaac tatgaaacat
     5521 ggttggaaga ttccttgcga caggaaatgg gtttgtccag tcaaggagtg cctgctattc
     5581 aatacgtcgc atttgatgag agaagtcagg ctatcgggtt cttaaatctt cgtttacggt
     5641 taaatgagag attacttgaa aaaggtgggc atattggtta ctctgtccgt cccagccagc
     5701 gtgggaaagg ttatgccaag gagatgctta aacaagctgt cagctatgcg atttccaaga
     5761 atatcacgac aattttggta acttgtgatg agactaatat tgcaagccga gcagttattg
     5821 tggctaacgg cggtatcttg gaagatagtc gaggtggaac ggaacgttat tggattgaag
     5881 aacaaagagg cgataagtga tggcagaaaa gtgttggaat aatcctaagc caaaggaatg
     5941 gcaggcagag gagttaagtc aaggccggat tattgactat aaggctttta actttgttga
     6001 tggtgaaggg gttcgtaatt ccctttatgt gtctggttgt ttattccatt gcaaggggtg
     6061 ttataatgct gcgacttggt cttttaaggc gggaatgcct tatacgcaag aacttgaaga
     6121 gcagataatg acggatttgg cacagcctta tgttcaggga ctgacacttt taggtggaga
     6181 accctttttg aatacgggta tcttaattcc tctgattaag cgtattcggc gtgaattgcc
     6241 agaaaaagat atttggtctt ggacgggtta tacttgggaa gaaatgatgc ttgaaacacc
     6301 agacaaactg gaaatgctgt ccttaattga tattctggta gatggtcgtt ttgatatcac
     6361 aaaaaagaac ctcatgttgc aatttagagg ctcttctaac cagcgaatta tcgatgttca
     6421 aaagtctttg gctgctaaag aagtgattat ctgggataag ttaaacgatg gggaccaaac
     6481 ctttgaacaa attagtcggg aggatttgct ttaagaagct gacttatcca catgattttt
     6541 ttgaaaaggt catgtgaaaa caggtccttt aagggtgaat tggggagaaa gtaattgtta
     6601 ttccctggtt ttccccacat tatcctcata gttatccaca ggttgtgtat aagttgtaga
     6661 attgtgaata aagactaaaa aagaggccta ggcctctttt ttgatataga caaattcatg
     6721 atctgttgat aggtctggat ggtagtaaaa accagcaaag acaaggcttt taaggctgtc
     6781 aacagtttgg caattatttt ccatacaggc agtgagaaat gcacctcgtg ccttttttga
     6841 aatggtggaa tgggttttga attggccctc tttttctgcc ataaacttgg gacttatcca
     6901 caattgttta cagtctttgg aaaagacatc gtcaaattca ctggataaaa gggaaatcac
     6961 ttggggatgc tctttggcaa actgattata acagggccgc cagtaagact tgaggctttg
     7021 tccttcaatt tttattctgg tgtgaaaatc atggcggtgc tctgcgatag gatgattagc
     7081 gggaatgata ccgtaaaagg atgaggtgat gtaaacctgc tgggtgaggt aagcctgttc
     7141 ttgggtagtg agcttatcgc gcttgatatg gcggtacata aggccattga acagttggta
     7201 ggcagggtaa gccaagcttt gttgagaggc catgtcttgc cagcgttgct gttctttttt
     7261 agctgactct tctttgatac gatatgattt ggccaagtcc tccgtggtca tagctgccat
     7321 gatttttaaa atggcttggc tgtcttgtgg aaggaggtgt gggtgagatt ccttagggat
     7381 cgtcatttct tttgcggttg gaattaaaaa ggttagcata gtgttattgt agtaaagtta
     7441 cttgctttct gtcaagaaaa ctagtcttgt ccaaggatga cgttcacacg gataccttcc
     7501 tcgtcttctg tcgtgaaaga agaagaatct tcttgtaaaa tagctaggcc gtgtaatctt
     7561 gcttttttga gagtggctga aaaaagcagg ggcgtctcaa tgtgaatggt caagaaggct
     7621 aagcctggag caccttcttg gtgttttttg aggtaagggg ctgaccagtg attgaatgca
     7681 aggtgatgat agtagttccc tgaagcaatc cagctagcac ttggaatggt cattttatcg
     7741 cctaaatcaa aaaccttttg atagagaagt gaagaagcca gagcattttt gacactcaga
     7801 tggacatggc gaatgcgtgt gtcttgagct agtaaaaagt gcttggggat atctgtcaac
     7861 tgctccaata tgcttttggt atccgtgggc tcagtcacac caataatttg accattgtcg
     7921 cggatatccc aatgctcaac agctttgtca tgataaattt caatcccatt accctcagga
     7981 tcgctgaggt agatagcttc gctatggccg tgatcagctg ctccttctaa agagatactt
     8041 ctggttaaga aatgattgag aacaagtccc aagctatgac gatcaggaac taaaaaggct
     8101 gtgtgataaa gaccataagc tttatcgcct ggtaaaggtg tttgtcgtaa ctctaagata
     8161 acggttttac cgtctgtagt caattgacga gatgtcgtgt cttgtgagag aacctgtaaa
     8221 ccgataatac ttgtgtaaaa ggttgtcatc tttgctagat cggtaacatt tagagaaacc
     8281 gttcctaaag agatggttga gttgtaaggg tatatcatcc tattacctcc aaaaactaat
     8341 taaatctatc ataatcaatc agtttcaaaa agaaaagtag gcacaaataa gtggtatagg
     8401 cactaaaaag taactcattt gtcagcccta tcttgtttct gttctctcta atagtctata
     8461 atgggttata agttacaaaa agatactaag aggagctgct gcctatgctg aaaaaaagac
     8521 cggcttgtcc cgtagaaaca accttatcgg taatcgggaa taaatagaaa ttattaatat
     8581 taagagactt gctaaagggg accttgcgtt ttgggcagtt gaagtcctca ataggttcgg
     8641 tcagtcaaaa ggtacttact gcccaattaa gggctatgga agcagacgga ttggttcatc
     8701 gggaagtgta tgcagaagtg ccacctcggg tggagtattc cttaacagaa actgggttga
     8761 gcttagctcc tgttattgaa gcgatgtcgg attggggcca aacttaccaa gaaaaacatg
     8821 ccgatttatt tgaagaaggc tagaggaaag agttgtccga gcagactgag acttagagaa
     8881 gctgagagtt tttaaaaaat gatattatca cattctttac agtttgataa aattactttt
     8941 tttctacaaa aagacttgcg ctcatctcac gaatatgata atataatatc aagtctgttt
     9001 gagaaaacag aagctcaggt caagtaagtg cacacttaca ataacacagt tgataatggg
     9061 gaaactcaga gtcaagaaaa agaaaagcaa gccttgcatt ttgcaaggct tttttctgtc
     9121 tttattttgg tctgcgccga gcaaaatcta aaaatttaaa tttttccagt ttatggcgac
     9181 tctcggtgaa ttggaattgg ttattattgg aaaggtagac tttggatttg acggaaacaa
     9241 catgttggtc tgatccaagg tcaagtaaaa ttttatcacg atcggttatt tggtcaatgg
     9301 taacctcttt gagggcaaag tcaatggcga gatggagttc cttttccaaa tattgataaa
     9361 tagaatgctc tgcgatttcc cttgtcatta ttggcaccaa agttttacta aggtaatcaa
     9421 tgtctaagac ggaagccaca ccctcaacaa cgcgttggcg tgtaacacgc cagaccaagc
     9481 tgtttttgct aaaaccggtc aattttgaaa gtgtctcatc cacaatcagt ttatcaatgg
     9541 caatgacgtt ggtcttagaa tctagatttg agtaagagac gagttcctga taactagtta
     9601 gttctgagat agggaacatg atctgatgat gtctaatcac ttgggtgcca cgtccttgtt
     9661 ttttgaggat aagacctgcc tttgtgagaa gtgagagagc cttgcggacg gtatctcggc
     9721 tagcttggta ttgttgactc aattctattt cagtaggtaa aaaatcccct tctttgtaaa
     9781 agtctttgtt tatttttgtt tcgaggtctt tataaatacg ttcatacttt gtcatagggt
     9841 aaattacctt tccatttgtc tattttttta cagacaacac cttttatttt accaaaataa
     9901 tggctttttt ggcacaaaca acttgtagac aaatttgcaa tcgattacaa taaaggtgtc
     9961 agttagattc tatctaagaa tttgaatatt tcattttgac gttgcttgtt aaaagcaact
    10021 agaacaaagg actaggggat gtcacatggg aaaatttgaa caggatgcta agagtcttct
    10081 aactgctatt ggtggtaaag aaaacatcaa ggttgtcaca cactgtgcaa cgcgtatgcg
    10141 ttttgttttg aatgataata ataaggcaaa tgtcaaagag attgaaaaaa tctctgtagt
    10201 taaagggaca tttaccaatg ctgggcagtt tcaggtaatc attggtaatg atgttccagt
    10261 tttttataat gactttacag ctgtttctag tattgaaggg gtgtctaaag aagctgccaa
    10321 atcagcagct aaaagtaatc aaaatgcctt acaacgggtg atgaccatgt tggctgagat
    10381 tttcacacct attattccgg cgattattgt tggggggctt attttaggtt tccgtaatat
    10441 tttggagagt gtgccttttg aatttcttgg gcagcaggtc gaaaaaggga aattagtttt
    10501 tgatgcagct ggggatcctg tttggaatac gattgtgagg gtatctcctt tctggtcagg
    10561 ggttaaccat ttcttgtggt taccagggga agctattttc cacttcttac cagttgggat
    10621 tacttggtct gtgacgcgta agatgggaac cactcaaatt ttagggattg tccttggtat
    10681 ctgtttggtg tcaccacaat tattgaatgc ctatgcggtg gcaggaacgc ctgctgctga
    10741 gattgccaaa aactgggttt gggattttgg tttctttacc attaatcgta ttgggtatca
    10801 ggcacaggtt attccagccc ttttagctgg tctgtccctt gcttatcttg aaattttctg
    10861 gcgtaaacgg attccagaag tggtttcaat gatttttgtg ccattccttt ctttgattcc
    10921 agctttgatt ttagcgcata cggtattggg gccaatcggt tggactattg gtaaagggat
    10981 ttcctttgtt gtgttagctg gattgactgg tcctgttaaa tggctattcg gtgctatctt
    11041 tggtgccttg tatgctccgc tagttattac tggtttacat cacatgacaa atgccattga
    11101 tacccaatta attgctgata ctgcaactcg tacaactggt ttgtggccaa tgattgctct
    11161 ttcaaatatc gctcaagggt cagccgtttt tgcttactat ttaatgaatc gtcatgaaga
    11221 acgtgaggct gaaatatcgc ttcctgcagc aatttctgct taccttgggg taactgagcc
    11281 tgccttattt ggggttaatg ttaaatacgt ttatcccttt gtagccggaa tgattggctc
    11341 aggtattgcg ggtctcttat caacaacctt taatgttcag gcaaattcta ttggtgttgg
    11401 tggtttacca ggtttcatgg ctatcaatgt gaagtacatg attccattct tcatctgtat
    11461 ggcagtagcc attgtggtgc cgatgttttt aaccttcttt ttccgtaaat cacatatcat
    11521 gactaagaca gaagatgaag ctaaactacc tgagacaccc gtttcggatg ctcctgtagc
    11581 aactgctcca cataagacta tgcaaggaac agttatcact ttaacaagcc ctttaacggg
    11641 tgaagttaaa gcgttgtctg aagctgttga tcctgtcttt gcacagggag ttatgggcca
    11701 aggtgctctt cttcaaccga cagaaggggt gttagtagcg ccttgtgatg ctgaagtatc
    11761 ggtcttgttc ccaactaaac acgctatttg tttggtgacg actgaaggtt tggaattatt
    11821 gatgcatatt ggcatggata cggttaactt agatggtcaa ggatttgaag ctttggtgaa
    11881 gcaaggtgat caggttaagg ctggacaaac attgattcaa tttgatatag cagcaatttc
    11941 tgaagctgga tacgccactg aaacgcctct tgtggtgact aatcaagatg tttttacggt
    12001 aactgttgaa ggtagtttac cgcgtcagat taaggttaat gataagttag cagtagcggt
    12061 gaaaaagtag gtttactaag agaaaacgtt caggaactga gatcagttcc tgaaactatt
    12121 ttagggagga aaactcatga caattgataa aaagaaagtc gtctatcaaa tttacccaaa
    12181 atcctataag gacacgactg gaaatggtgt gggagacttg ctagggatca ttgataaatt
    12241 gccttactta caagaactag gaatagatat gatttggttg aaccctttct accctagtcc
    12301 acaacgagac aatggctatg atgtttcaga ttatacggcg gtcaaccctg attttggaac
    12361 aatggctgat tttgaaaatt tggtaaaagc tgctaaggag catcagattg agttaatgtt
    12421 ggacatggtt ttgaatcact gttccacaga ccacgagtgg ttccaaaaag ctttagcagg
    12481 agacccttat tatcaggatt tctttatctt gagagatcag ccgactgatt gggtttccaa
    12541 atttggtggg aatgcttggg cgccttttgg agatacaggc aaatactact tacacttgtt
    12601 tgatgtgaca caggctgact tgaattggcg gaacccacat gttcgtgagg aattggctaa
    12661 agtggttaat ttttggcgag ataaaggagt gaaggggttc cgttttgatg tgattaacct
    12721 gattgggaaa gatgaagagc tggtggattg tccggtcaat gatggtaagc cagcttatac
    12781 ggatcgtcct attactcaca cttatcttca tgatctcaat caagccagtt ttggtcagga
    12841 tgattcgttt atgacagtag gggaaatgtc tgcaacgact attgacaact gtcttttata
    12901 cacggctccc gaacgtgagg agctatccat ggcttttaat ttccaccatc taaaagttga
    12961 ttatgagaac ggtcagaaat ggactattat ggcttttgat tttgcagcgc tgcgagactt
    13021 attccatgct tggggtgaag gcatgagtca gggcaatggg tggaatgcct tgttctacaa
    13081 taaccatgat caaccacgtg ccctgaatcg ttttgttgat gtaacacatt tccgaaacga
    13141 aggtgcgacg atgttagcag cttccatcca tttgtcacga ggaacgcctt acatttatat
    13201 gggtgaggag attggcatgc ttgatccaga ctttgatagt atggatgatt atgtggatgt
    13261 ggaaagtctc aatgcttact caagcttatt agtctcaggt aaaagtgcag aagaagcctt
    13321 tgccattatc aaggccaagt caagggacaa tgccagaaca ccaatgcaat gggatgctag
    13381 tgaacatgct ggctttacga ctggtaagcc ttggttagag gttggcaaat cttatcgaga
    13441 catcaatgtc gaaacagaaa aagagggacg tatttttcct ttctaccaac gcttgattgc
    13501 tttgcggaag gaactcccta ttattgctga aggggactat cgggctgctt ttaaagatag
    13561 tcaggctgtc tatgcctttg aacgccattt aggtgaccag tgtttgcttg ttctcaatca
    13621 tttctatgct gatgaggtcg aactggaatt acctccacgt tatcaacatg gacaggtctt
    13681 aatcagcaac tatgagaaag tttctatttg tgaaaaagtg atactgaaac cttatcagac
    13741 acttgctatc ttagctgata actaactaaa agcctgaggt taggcctcag gcttttgctg
    13801 attgtcacga aaaaagaagt tttctcatat atttattttt aaactcttat tttttctaaa
    13861 taaaaacaat tgagataagt tattttagct aaattttggt acaatggaaa agattataag
    13921 tagagtttaa gataaagatt ctacaaattt aaaatgatat aaggagatac gaatgacaac
    13981 ttatcaagat gatttttacc aggctgtgaa tggaaagtgg gctgaaacag cagttattcc
    14041 agacgacaag cctcgaacag gtggattttc agacttagca gatgaaattg aggcattaat
    14101 gctagacact acagatgctt ggctagctgg agaaaatatc cctgatgatg ctattttaaa
    14161 aaattttgtg aaattccatc gtttggtggc tgactacgct aaacgtgatg aagttggagt
    14221 aagtccaatt ctccctttaa ttgaagaata tcagtcctta aaatcttttt cagaatttgt
    14281 tgctaatata gcgaaatatg aattggcagg tttaccaaat gaatttccct ttagtgtggc
    14341 accagacttt atgaatgctc agctgaatgt gctttgggca gaagcaccaa gcattctttt
    14401 gccagataca acatactacg aagaaggcaa cgaaaaagct gaggaattgc gtggtatttg
    14461 gcgtcagtcg caagaaaagc ttttacctca atttggtttt tcaacagaag aaatcaagga
    14521 tcttttggat aaggtaattg agctagataa gcaattggcc aagtatgtct tgtctcgtga
    14581 ggaaggctca gaatatgcca aattatacca tccttatgtg tgggctgatt ttaaaaaact
    14641 agctccagag cttcctttgg atagcatttt tgaaaagatt ttaggccaag tacctgacaa
    14701 ggttattgtt cctgaggaac gtttttggac agaatttgca gccacttatt actctgaagc
    14761 caattgggat ttactcaagg ctaatttgat tgtggacgcg gctaatgctt acaatgctta
    14821 cttgacggat gatattcgtg tggaatcagg cgcttattcg cgcgctcttt caggaacacc
    14881 tcaagctatg gacaaacaaa aagcagcctt ttatttggcg caaggaccgt ttagccaagc
    14941 gcttggcttg tggtatgctg gtcaaaaatt ctccccagaa gctaaggctg atgtggaaag
    15001 taaggtagca cgcatgattg aggtttataa gtctcgtcta gaaacggctg attggttagc
    15061 accagccaca cgtgaaaaag ccattactaa attaaatgtt atcacgccac atattggtta
    15121 cccagaaaaa ttaccagaaa cctatgctaa aaaagtgatt gatgagagct tgtcattggt
    15181 tgaaaatgca cagaacttgg ctaaaatcac gattgctcac acttggagta aatggaacaa
    15241 gccagttgac cgtagtgaat ggcatatgcc agcccactta gtcaatgctt attatgatcc
    15301 tcagcaaaat cagattgtct ttcctgcggc aatcttacaa gagccatttt attctttaga
    15361 tcagagttct tcagccaatt atggaggaat tggtgcagtc attgcgcatg agatttcaca
    15421 tgcctttgac accaatggtg cttcctttga tgaacatggt agcctaaatg attggtggac
    15481 acaagaagac tatgctgcct ttaaagagcg cacagataag attgtggcgc agtttgacgg
    15541 cttagagtca catggtgcta aggtcaatgg taaattgaca gtttcagaaa acgtcgctga
    15601 tctaggtggg gtagcttgtg ctttagaagc ggcacaatca gaagaagact tctcagcccg
    15661 tgacttcttt attaactttg cgacgatttg gcgtatgaag gcccgtgagg aatacatgca
    15721 aatgctagct agcattgatg ttcatgctcc gggtgaactg cgaacaaatg tcaccttaac
    15781 caactttgat gctttccatg agacctttga tattaaagaa ggcgatgcta tgtggagagc
    15841 tccgaaagac cgtgtgatta tttggtaatt aggtagttga taaaccttca aatgcctgtg
    15901 attataaaaa tgactgattc tgtgaaacac aggatcagtt ttttgcttcc ttattggtgt
    15961 ccgttttgac acaacaaaaa gacaaccctc aggaaagaag gttgcctttt ttagacttat
    16021 cagaaataag tgattagttg ttaagggcag cagccatagt agctgcaact tctgattcaa
    16081 agtcgttagc ttttttctcg ataccttcac caacttcaaa acgtgcaaaa gcaatcgctt
    16141 tagcgtttac tgagtcaagg taagcttcaa cagttttgct gtcgtccatg atgtaaactt
    16201 gtgcaagaag agtgtaagct tggtcaactt tagtgttgtc aagcatgaag cggtccattt
    16261 tacctgggat gattttgtcc cagatctttt ctggtttgcc ttcagcagca agttcagctt
    16321 tgatgtctgc ttcagcagca gtaatcacat cgtctgataa ttgagctttt gaaccgtatt
    16381 tcaagaatgg aagagctggt ttatcaacca ttgcacgaga ttcgttgtca agttcgatag
    16441 cgtggttcaa ttgagcaagt tcatctttga tgaattgtgc atcaagctca gtgtatgaaa
    16501 gaacagttgg tttcattgca gcgatatgca ttgatacttg tttagcaaga gcatcgtcgc
    16561 cgccttcgac aactgagata accccgatac ggccaccatt atgttggtaa gcaccgaagt
    16621 gttgctcatc tgctttttca atcaaagcaa aacgacggaa tgagattttt tctccgatgg
    16681 tagcagttgc attaacgtaa gcttcagcaa gagtttcacc tgaaggcata acaagtgcaa
    16741 gtgcttcatc gttgttagct ggtttgcctt cagcgataac tttagcagtt gcgtttacca
    16801 attcaacgaa ttgagcattt ttagcaacaa agtctgtttc agcgttaact tcaacaacag
    16861 cagcaacgtt accatgaacg taaacgcctg ttaaaccttc agcggcaaca cggtcagctt
    16921 ttttagctgc tttagccatt cctttttcac gaagaagttc aacggctttg tccatgtcac
    16981 catctgtttc aacaagtgct tttttagcgt ccataacgcc agcaccagat ttttcacgta
    17041 attcttttac aagcttagct gtaatttctg ccatgtgtag tatcctccaa atgatatttg
    17101 ttttggtttc aaaaaacgag acagagcggt ttgctttctg ccccgtttgg ttttcgattg
    17161 ttaaagacaa acaaagtttg ctataagagt taggaactct gtgctaatta agcgttgtcg
    17221 ccttcgacaa cttcaacgat ttcttcgatt gaatctgctt gagtgtcagc ttcaaaagca
    17281 acgtctgcat cttcaccttg acggccttcg ataatagcgt cagctaattt agcagtgatt
    17341 aatttaacgg cgcggatagc gtcatcgtta gctggaatga tgatatcgat atcatctgga
    17401 tcagcgtttg tatcaaccat cgctacgact gggataccaa gttttttagc ttctttaaca
    17461 gcgatttgtt ctttatgtgg gtcaacaacg tacattacgt ctgggatacg aggcatatct
    17521 tcgataccgc ccaagaattt ttcaagacga gcgcgttgtt tgttaagaag tgcaacttct
    17581 ttcttaggaa gaacgtcaaa ggttccttct tcttccatac gtttgatttc tttcaaacga
    17641 gcgatacgtt tttggatagt tccccagttg gtaagcgttc cacccaacca acggtggttg
    17701 atgaagtatt ggcctgcacg cgttgcttcg tcagcaactg cttcagcagc ttgtttttta
    17761 gtaccaacga acaagatgac agcatcgttt gctgcagcat cacgaacaaa ttcgtaagct
    17821 tggtcagcta attttacagt ttgttgaaga tcgataacgt ggataccgtt acgctctgtg
    17881 aagatgtatt tagccatctt agggttccag cgacgagttt ggtgaccaaa gtgaacacca
    17941 gcctcaagaa gttgtttcat tgaaattact gccatgagta gtttctcctt tataaaatgt
    18001 tttttcctct tccagacttc gacttgcagg ctaacctatc ggcaacaagc ccacaattgg
    18061 tctagaatga gtatttgccg tctacacgac cttactatag tatcaaaaaa agaggttaaa
    18121 agcaaggaga aatgctatgg attcccttat ttttgagatg actagcttct ttgtttattg
    18181 gtaagtgtta agacaagctt ttgctcattt tgggtgacac ttgccaaatc gttttattta
    18241 agatatagtg aatttgacta atttttggag gcgttttcat gacgaagggt attcgatttc
    18301 aattgcttgg cagtccccac atttttcttg atgacaaaga acaatttttt gcctttgcca
    18361 aagcaaatgc tctcctttat tacttagtgg ttaatggatc tgttagccgc gaggtggcgg
    18421 cgagtctact ttgggaaaat aagaacacgc aaacagcgaa aaagaattta cgaaacgcta
    18481 tctaccaggt caataaagtc ttgcaagctg atgtgattat ttgtcccaat cgcaacctgc
    18541 tggttttgaa taaaacactt gatatcaaaa cagatattaa cctttttctg gctgatccgc
    18601 tagctcactt agaactctac caaggggagt ttttgcaggg cttttacctt aaaagtggtg
    18661 aggaatttga tctttgggtt tcaaaaatgc gtatgcagta tgaacaggta tacctaaaag
    18721 cgtgttacca aaaaattgaa gaaaagctct ctttagatgc cattgaagat gtcgaggaac
    18781 atttaaaaca gcttattgaa cgtgatgaat ttgaagagaa aaattatcag ctcttgatga
    18841 ggctttatca gcaggggaat tgtcctggta aggtcatcga aacttattat cagttggcta
    18901 atgtgttgga taaggagcta gggattcagc caagtttgca aagccaacag atttatcagg
    18961 aagtggtcgc taaagatcgt aatgaacgca aaatcaagca ttttttgcgc aacagtaatc
    19021 attttttggg gcggattgat gagattaagc agctggaaaa ctattttgcc aactgtttgg
    19081 cctgccaaga ggtaggagct ctgctcttaa ttggtgatac agggattggg aaacgaaccc
    19141 tagccagaca ggtcttagcc aatcaaaccc aaacgtttca aattgtcaca gctaaatgtt
    19201 ttcgtgaaga ggctatggat tccttattgc cttggcgtaa tatcttagat ggcctgggag
    19261 atttggtgat tcaaaaccgc ttattgacca ccaaagcttg gaaggctgct cttaaacgct
    19321 gttttcctgt ggcaaccatt tttcaagaag ataacaacca accctttatc aaggaccaca
    19381 ccagcttgtt ggtttccttt attgttgata ttttacaaca tttggcagaa atcaaggcgc
    19441 tggtaatcct tattgaggat tgtcactgga tggatgagga tagtttgacc ttgttgcaac
    19501 gggtcatgaa tcaattggtc cactatccga ttgcttttgt cttgaccaag catctaggaa
    19561 cgactcctga gctcggtctt tgtttgaatg ctttgatgag tcaagggcgt ttagaaagca
    19621 tttgtttgga gccttttaat cggcaagaaa gtttggttta tattaacagt caactgggta
    19681 gtcagccagt gacggcagaa gaaatggagc acctctatca agccagccaa ggcaaccctt
    19741 tctttttgtc agaatacact caggccctac tgcgtcacga aaaatttgtg cctttaacgc
    19801 ctgccattaa ggctaagttg ggtcttaaac tagctaatct aagtagtcgt gatgacgcat
    19861 tgttaaacta tttgtcttgt tgtcggaggc ctatccctct aaataccctc gctcaattga
    19921 tgttactgcc tttagaagaa gtgatcgaga tggtggataa tctggggcac tactatattt
    19981 tggtagaaga aagcgtagga gaggaagtgt tgatttcatt tcgtcagcgg attattcaac
    20041 tctatagtta tgaccgttta tctttgtcaa aaaggcgttt attgcacgga caaattgcca
    20101 aacggttaga agatttactg cctattttga caccaagccc tcacttatta gatgacattg
    20161 cttaccatta tcaggaatca cggcaggtga ttaaggcttt ggaatacaac cttaactatc
    20221 tagatgctac cttgccattt cagcatgagc tgtttcccat ttattcaaag agtattggct
    20281 ccttggaaaa gtcagatcgt gaccatcaac gcttaatgga agagcagttt gataagattc
    20341 gtcaaagcat tgcggatttg gaactgacct atgataataa ccgtgatttc cagcagttgc
    20401 ttattcgttt ttcttacctt gaaggccgtt atgatattcg aacagggagg tatcaagaag
    20461 ggattaaaca cattcaaaag gtcatcgctt tggcaaccga gctaaaacag ccctccttct
    20521 tgctagaagg ctatcgccag ttaattcatt actgtatcca agtggaaaac aagccagaaa
    20581 tgcgttatta cactagtctt tcattggagg cagcggttgc tgctaatcat tttgaggcca
    20641 ttgcgattag tttgcggtta aacggtctct atcatttgat tattggggag ttaaatgagg
    20701 cagagcgtct gcttcaacag tcgattgact tcttcaaggt gacgccaggc ttgcaagcta
    20761 actatgcgat tcagattgct gctgccttag attatttggg ggagattgcc cagattcgct
    20821 atcagtttga aaaggccgtt gcttatcaaa aacaagccat tgccttgacc gaaaacaagc
    20881 cagctgagtt atcggcgagt attttttata ttggattagg gatttcctac ttttatttag
    20941 ctgattttga acaagctgag caaatcttga gtttggctaa ggaagctttg gtcaatcata
    21001 gttatccttg gaaagaaacg caacttgaaa tttacctggc tatgattcaa tggaaaaagg
    21061 gcaattatca gccagccttg accctacttg attacagaga aaccttgatg tctaggtatc
    21121 gcaatccgcg tgataagggc ttggttttct atttgatggc tgtggtcaag taccaattga
    21181 tatttcaagg agctacccta agtcagcagg aaaaagaaat ggcagaccac ctgttgtcag
    21241 aatcctttga gtattattat gagattgcta gtactaacct caacccttac cgagattgtc
    21301 atttggtgag tgagttgaac gatttgcgtc aacaattatc tgctaaaagc taaggaaaac
    21361 cctctgaagt gaatcagagg gttttagcta tgttgtgcca taatctgtac gaggtaaaag
    21421 ataaaggtgg ctgctaaatt ggcggtgtgg ttatcaatat cgtgtggtgg tgaaacctca
    21481 accacatcaa agccaactaa ttttccgcta gctgcaatgt gttgcaaaac taagacggca
    21541 agatttgggt caacaccgag ggactggata gcactaaccc caggcgcagc accaactgag
    21601 aaacaatcca tgtcaatggt caggtagacc ctttcttgcc cttctaagaa acggtcaatg
    21661 gctcggcaga ccttttgatg gcccatttgg tagatgtctt gacctgttaa aaattgaatg
    21721 cccttggatt ttgccacaaa gtcaaatagg aaaaggttgt tattatgttc ttgaatgcct
    21781 aaaacgaagt atttaaagag gcgtttgtca gcaaccgcat cgtcaaacat ctgtcgaaag
    21841 cctgtccctg aattagggcc tgtttggtcg taaggcctta aatcaaagtg ggcgtccata
    21901 ttgatgacag ctaggtcatc acttggggat aggctttggc gtaggcctaa gtagtggccg
    21961 taggcggttt catggccacc tcctaagacg atgggtttga gattgaggtc acacatccgt
    22021 ttgatggctt tgcttaaact gttttgcagt tgttccaaag agcgattggg gccgtcaatg
    22081 ttacccacat cgtaaaccat aacttggttt cctaaatgcc aagggaattt ggcgagctgg
    22141 gttcgtatgg cagctggact ttcgaccgct ccgacacgac cattattgat ataaaccccc
    22201 ttatcacttt taaagccaat caaggcaaaa tgtgtccctt caaatggggt tagtgagctg
    22261 tcgttaaggt caaggaaagt catgaccatg ccccatttgg cagtatataa gtcatcgtcg
    22321 atcccaccat gataatagct agtggtggat gggtagtaat cttctagcat gcgcgtcatc
    22381 tcctttagga ttatgatagc aaaataaaac ttacagtcaa cactttcttg gcctttgtca
    22441 ctggttttta ggaatagcag agcaataaaa tcgtctgctt ttggtcccgg ttagttagtc
    22501 taaagaggcc atgacctctg ccacagcccc tctagttaaa gaagtacctt attcactaaa
    22561 attggatact caactcaact gcctgctcaa ccgcttcgag gaagcttggg tcttcaatga
    22621 ctgctgatgc cttgtttagt tcatcgtaga tttcgatgtg tttatcgtgt tcgataaagt
    22681 tgacttcctt gcggaagaga tcgtaggcaa ccttagtccc tttacctagt tcatgatttt
    22741 caggtttgag atcaagggct tggcaggctg ccatgatttc agtagccacg atgcggcgag
    22801 aatttttaag gatttcaaag gccttgcgag cagcggtggt gcccatgctg acaaagtctt
    22861 cttggttctc acaagatggg atagaatcca cactggctgg atgtgccaaa accttgtttt
    22921 cagaagcaag agaggcacag gcgtactggg taatcataaa gcctgaattg agacctgggt
    22981 atttgacaag gaaggatggc aatttgctga gctggctatt gaccaaacgt tccacgcggc
    23041 gttcagaaac atttccaatt tcagaaatgg cgatgcctaa gaagtcaaat ggctgtgcca
    23101 ttggttctcc gtggaagtta cctcctgaaa taacgtggcc atctttacag ataattggat
    23161 tatctgtgac agaattgatt tcaatgtcaa ctttggattt gacataggcg atactgtctt
    23221 tgctagcccc atgaatttga ggcatgcagc gcaaggtgta agggtcttgc acacgagatt
    23281 gagtagctac ggttgtgttt tggctgcctt caaggaggtt tcggatattg cgggctgttg
    23341 ccaactggcc gctttgtggg cgaatggtgt gaaggttttc ttcaaatgga ctagtaatcc
    23401 cgttatgcac ttcaagggat agggcaccag ctaggtctga cagtttcaat aattgaatgg
    23461 cgtcataggt tgcaagggca ccgactgcag tgagaacagt tgttccgttg ataagggcga
    23521 gtccttcttt agcggctaaa gaaatcttgt caataccagc tttatcaaga gcttcttgac
    23581 cagaaagaag ctctcctttg tagtaagctt tccctagacc aagcatagga agcaccatgt
    23641 gagcaagcgg cgccaaatct cctgaagccc ctagagaccc tttttcagga atgtaaggat
    23701 gaaccccttt attgagcagt tccaacagtt tttcaatggt ggatagacga ataccagaat
    23761 accctttgac tagtgaattg atacggatca gcatgatagc tctcacggca tcttctggca
    23821 atgggtcacc aaatccacta gcatgggtac gaatcaaatt ttcttggagt tgaactgtat
    23881 cttctggtga gatgctcacg ttacaaaggg atccaaaacc ggtggtcacc ccgtaaacca
    23941 cccgtttttc actgacaatg tcatcaacaa ttttacgaga ggcattcaca gcttcaatag
    24001 cactatcatc aatgtgacag gctacgcctt ggcgagcaat cgcaatcacg tcttcgatag
    24061 taaggctttc gccatctaaa ttaatcactc ttgtcatagt ttttctccta gatttgttcc
    24121 ttagggggca tttggtccat ttggtggtta cgtccgtgca taaggtagta cacactactt
    24181 gcaatgatga caccaactgc accataaaca aagttcattg ggttgtcacc ccaaatcata
    24241 actaaactaa cgataactgc aagaattggg ataatagggc caaatggtac tcggaagatc
    24301 acattagcat cgggatcgtc cttccgtaat ttcataacgg ctagtgctgt tggaatgtat
    24361 tggaagaagc ggaaaacaac actgagtttt gctaagcttt caaatgagcc agtaagcagg
    24421 agtacaatgg caattgctcc tgaaaccaag atagcaacga gtggcgcgcc attttgattt
    24481 tgcttggcaa tagcagctgg taagagccct tcatcagcaa tggcagcacc gtaacgtggc
    24541 accatgatgg attctcccat gttaagacct gtaatggaaa ttaaagcacc gattgagacc
    24601 atccaagcgc cagcagggcc tatcatttta acaaaggcat cttgaacagg tgcattggtc
    24661 atcatgattt gagagccaag catggcaatg gttccaccga taatcagcat atataagaca
    24721 gagacgatac tgattgatcc taaaagagca agcggtacat ttttttcagg gtcacgcatt
    24781 tccccagcga caatagagag ggtttcaaaa ccgataaagc catagaagat ataaacagca
    24841 gtattggaga tagcccctaa gaggttagtc cctggttcca actgaacaaa tggggtaaag
    24901 ttaggaagcc cgtttttgat gaagaaaagg gtacaggcac aaaaggcaac gattggaatt
    24961 aacttagcaa tggtggctgt gatggtgaca attttagagg ttttcaaacc agcgatattc
    25021 atcaaagata gtaagatgat taacccaata ctaagtggaa tgtgccaacc ttcaaaggca
    25081 gggaaagtaa tgataaacat tctggcaaac ccagctgcca tggctgccca agcgaagatg
    25141 gtaacggtcc aaccaaggaa gccaacgtta aagccaataa aatcaccaaa agctcgtttg
    25201 gaatattgga aggctccgcc gtttttccca aaataaccag agacttctgc aaaacaaact
    25261 gccaacatga tggtcaaaat agctgttcca aacataacag cgatggatgc agggccaagg
    25321 cccttataaa tggccctagg taagagaaaa ataccagagc cgataacggc attgatcccg
    25381 taaagagtgg caccgctcaa gctaaacttt gcctgttctc tttcttgttc gttcatgtga
    25441 tttgacgcca taataatgct ctcctttttg tttgcaaatt gcgttcaaat ataatggata
    25501 aggtcgctag gaaatgagga gatagtcggt ttaggaggat ccttcttgca cctaacgata
    25561 gtgatgagct attggttagc gatgagaaat aggtagcctt ttgtaatgat gtgtagtgat
    25621 ttcattggag aagaataggc atgagtagtg tgatgcctat ctttatccca ctaagtctta
    25681 taccataagc ctgcccaaac agctactgga gtttgggcgg ggcttgtttg attgaggcaa
    25741 acttttagat ctgaaaggct ggcctcctgc tcggttacca acaagtgatt ggcttcaagc
    25801 tcttgattcg cctgattggt cacagaataa gtcagtttgc ttagggcata aagcagttga
    25861 cagtccgctt taggtgcctc aaatggtgtg tcagaccaga cgggtaataa ttgcccttgg
    25921 tattggtcat catacattaa attgatgtct tggcaggttc cacgactgac gattctggta
    25981 tcgccttcaa acgcataggg ttgaaaagga gctagggaaa tctctttagc atgactcaaa
    26041 tcacttaatg tgatgggctt gtctaggctc attagaatcc tgtgatagcc atcaagtcgg
    26101 gtaaaggttg tctgtcgtag ggctacagtt gcagttgaga gacgataaga gaattctctc
    26161 tttttgtaat ctccatcttc gggataaagg aacaattggt tggtttcacc gccagaccag
    26221 tcagtttgga ggtaatcaga gggcgctttg atggttacct ttgtcatttg ttctctcctt
    26281 atttccaatt agaatagtcc tgtgatgttg ccctcctcgt caatatcaat tgtttcgctg
    26341 gcaggtactt ttggaaggcc aggcatggtc atgatagcac ctgttagggc aacgataaat
    26401 cctgctcctg cggacacttt aaggttgcta atagtcactg taaagtcagt tggtgcgcca
    26461 agttttttgg catcgtctga gaaggaatat tgggttttgg ccatgcaaat tgggtagttg
    26521 ccaaagccga ggcgttctaa gtcagccagt tcacgtttgg ctgctgagct caagttgatg
    26581 cctttaccac cgtaaacttt ggtaacgatt ttagtcagtt tggtttcaat gctatcgtct
    26641 tcctcataaa caaagcggaa ttgattgtct tgctcggcta gtgtcacgac tttttcagcc
    26701 agttcacggc caccagctcc gccatttgcc caaacatcag aaatcacaac gtcaacgcca
    26761 cgtttgtcgc aggcatcata gacagcttgt aattcggcat cggtatcaag cgggaattta
    26821 ttgatcgcca cgacaactgg aaggccatag acgtcttgga tattagccaa atgtttgtca
    26881 aggttaggta aaccatccac aacggcctga acattttcag tagccaggtc tgcttttggc
    26941 acacccccat gcattttaag ggcacgtata gtggctacta ggacaacggc tgctgggcga
    27001 aggcctgaca tgcggcattt gatgtcaatg aatttttcag ctccaaggtc agcgccaaat
    27061 ccagcttcgg taacggcata atcaccatat ttcaaggcta gtttggtggc gaggacacta
    27121 ttacagccat gggcgatatt agcaaatggg ccaccgtgaa tgagggctgg tgtgtgttcc
    27181 agggtttgca cgagattagg atgaatcgca tccttgagca gagcggctag ggcaccacca
    27241 gctttcaagt ctttagctgt tacaggttca ccttggtagt tgtaaccgat gatgattttt
    27301 tcaaggcggg ctttgaggtc agaaatattt tcggataggc acaggattgc catgatttca
    27361 gaggcgacgg taatgtcata accatcttca cgaggaatcc cgttgacctt gccttgcaag
    27421 ccgtcaacaa tatgacgaag ctggcggtca ttcatatcca ccacacgttt ccaagtgata
    27481 cgtctggaat caatgcctag gctattgcca tggtgaatgt ggttatcaat caaggcagct
    27541 aataagttgt tggcgacacc gatggcatga aagtcccctg taaagtgaag gttgatgtct
    27601 tccattggga caacttgcgc gtggccaccg ccagcagctc ctcccttaac cccaaaaaca
    27661 ggaccaagag aaggttcacg aagggcaata actgcttttt ttccaatggc agaaagagca
    27721 tctaccaatc caacagaagt ggtggttttg ccttcaccag ctggtgttgg tgagatagca
    27781 gtgacaagaa tgagtttgcc atcaggtttg ttttttaagg cgaccagttg acgggcatca
    27841 atttttgcct tgtacttacc atagagacag agcgcctcct tgtcaatccc taattgatcg
    27901 gcaaccttac tgataggttc catagtgaca gagttggcta tttcaatatc tgataaaacc
    27961 atagttgctc ctttacttgt taaacaatat cgagaatttt cgtgtagatg tcatctgcca
    28021 aatgacagcc cttgtctagt aaggcttgtc ctttttggcg atagtcggta acaaagtctt
    28081 catctttgat gccagacaga ttaatcaaaa cattcaacca agcgccttgt aaacctgctt
    28141 ttaagtttaa agcagcaact cctaagtcgc tagcagcatt tgtattagac ttaccgacag
    28201 ctgttgcagt gatctcaagt gcttcgacca tgagggtcat catctcaaaa ggtgattgtg
    28261 cagctgtttt caaggccttt tgcatggcag ttcgtctagc agccttgtct tcgtcagtct
    28321 cttttggcat atcaaaaacg gcagaaacca ggttgaaggc ttcggtatct ttgtcaatgg
    28381 ctgcaagcaa gctagcttgt agagcggtgc ttttagcatg gatctctgta ataatatctt
    28441 ggtagtcagc gtattttttc ttaccaagag tcaattcaca gaccatcttg gttaaggaaa
    28501 tgccattagc gccagagaga gcagcagcag aaccaccacc tggagcaggg gcatctgagc
    28561 caaggacttt agcgaaatct gttaagctta aatcaactaa acccatagag aacctcctaa
    28621 cctagcaaat ggttttcaag aatctgttta tggtagtcaa agtcctcaac ttgtaagtag
    28681 tattcagcca catcgattaa ggccttggct ggcgctaagc cgatgacttc agaaccaata
    28741 acattcacac cgtagcgacg cgcttcaaat ttgatggttt caaaagtacg gtaaagagaa
    28801 catttttcaa agttaaccat gttcatggaa acttgggcaa tatgacggtc ttctaacatg
    28861 acaccgatag ccttacaata tttgtagcca ccacctgaac cgcggataat tttcgcaatt
    28921 ttatgagcaa tgtcgatatt gtcagtatcc aaattaacat tgaaagcaac caatggcatg
    28981 cgagcaccaa cggcagttac cccagcagtt gggtgaatct tacgatctcc gtagtcaggt
    29041 gcccaatcct cttccaacag tttttctggc atgccttcga attgtccttt acggactttg
    29101 gccaggtttt gacgttctgg gcgtgtggca gaatcttcat aaaggaagat tgggattcca
    29161 agttcacggt taatccgttc tgcgacttgt ttggaaatct caacacattc ttgtgtagtg
    29221 atgtctttga tcggaacgaa tgggcagaca tcggttgctc ccatacgagg gtgttcgcca
    29281 tgatgtttgg tcatatcaat gttttcagaa gcgtatttca ccagttggaa agctgcttct
    29341 tgaatagact ggtcatctcc aaccaaggta aacacgctcc ggttgtggct cgcatcagaa
    29401 gagtagtcga gaagggtcac tccaggaata cttttggccg tcgctaccaa accatcgata
    29461 acagcctgat tttggccttc tgagaagttg ggaatacatt caacaatttt cgccatgttt
    29521 aatctccttt tatgtcattg aattactcat taagggaata ggttatctac tttagataac
    29581 gcttacattt ttagctagca gttattagtg aaataattga tctactgctg aagtcacaag
    29641 gtcatcatca gccaagtatg ggatagtgat gtgatcagta cctgcatgga gacgattata
    29701 ctcaatagcg gtttcaatag cgtgctcatt gcgagcccaa ttgcgacgag caacaccacc
    29761 catggtgtcc caagcaatag cagatttaat aatctcatca atgcgttcgc tgccatctaa
    29821 aacaagtccg aaaccaccat tgatggcttt accaatacca gttccgccac cgttatgaag
    29881 agccactaaa ctcataccac gcgcagcgtt accagcgtaa cattgcaccg ccatatcaca
    29941 ggtcacattg gaaccgtctt taatgtttga ggtttcacga aatggtgagt cggtaccaga
    30001 cacgtcatgg tggtcacgac caatcatgac aggaccaatc ttgcctttgc ggaccaattc
    30061 attaaattta agggcgatag tcacacgacc gatacagtct tggtaaagga tccgggcttg
    30121 ggtaccaact acgagttgat ttttctcagc atcacgaatc cagttgtagt tatcacggtc
    30181 ttgatagcgg cggtcaggat cgatagcttc catggcagct ttgtcagtgg ccaccaagtc
    30241 atcgtgatta ccactcaagc agacccaacg gaaaggtcca tagccatagt caaaaagcat
    30301 aggtcccatg atatcttcca cataggatgg ccagataaat ccgtctttgt cgttacgacc
    30361 attcttagaa atttctgtaa taccagagtc gtaaacagac ttcataaagg cattgccgta
    30421 gtcaaagaaa taggtgccat tttcagttaa cgtcttaata gcttcaaaat gccgtgccaa
    30481 ggtatcatca accatttggt ggaaggtatc tttatcttct gccaagagcc gggttctttc
    30541 gtcaaagcta atacctactg ggcagtagcc accgtcataa acgttgtgac aagaggtttg
    30601 gtcagacaaa agatcaacat gaatctgctt gtcattgacg tactctaaaa gatcaacgat
    30661 attaccatgg taagcaatcg aagtggactc cttagcatct atggcttttt gggctaattg
    30721 cagagcttct tcagggcttt cggcaatttg actgatccag ccttgagaat gacgggtttt
    30781 aatccgagat tggtcaactt cagcaataat ggcaactgct ttagcaattt cagcagcctt
    30841 accttgtgcc ccactcatgc ctcctagacc agatgagatg aagagtttac cggtcaaatc
    30901 accgtcatca gccactccaa gtttgagacg accagcattt aagagggtat taaacgttcc
    30961 atgaacgatt ccttgtgggc caatatacat ccaaccacct gcggtcattt gaccatagtt
    31021 ggtgacaccc atctcttcag cgatttccca gtctttcatg ttgtcgtatt cacccaccaa
    31081 aaggccatta gtaataatca cacgaggcgc ttcaggtttg gatttgaaaa gaccaactgg
    31141 atgaccagac tcaaccacca aggtttgttc atcagtcatg acttctaggt attttttaat
    31201 caaacaatat tgcatccagt tggcacaaac agaaccagtt tctccatatg tgactagttc
    31261 gtaagggtac aaggcaattt caaaactcaa gttattgtca atcatgacct gcatggcctt
    31321 ggcagctgta caatttccct tgtactcgtc aatgggtttg ccgtaaatgc ggtcttttgg
    31381 tctaaagcgg tagccataaa tacggccacg ggttttgagt tcttccaaaa attctggaat
    31441 gacttcttcg tggaacttcg taggtacata gcgtagggca tttttcaagg cgatttcggt
    31501 ctgagcctgg gtcaatcgaa aacctctgtc tggtgctctt cggatacctt cttcaaacac
    31561 agtcttttcc ggtaaaacat cgtctaactt aacagtcata gcggcagcta tgtcagtttc
    31621 actgtaaaat gacatagaaa actcctcctc aactcctttt tattgtcgag attagtctaa
    31681 cttagtctag tctataaaaa gtcaaccacg ctttgaaatg cgaaaaaagt ctaaaaaaaa
    31741 atcaaaacct cattttttga ctaaaatttg acgcttaatc agtacacttg aggtatgaca
    31801 gataaagtca gtcagaggtt aattgttgtt accaaagttg caaagatcgc aactattgag
    31861 tgggtgaggg gggactagta atggctatta atcagttgac aaacgatgtt aaaaaaggag
    31921 gtttttatgg ttgctgatgt cttattaaca cattttaatc aactattttg tctaaatgat
    31981 ccaggtcatc ctttaactgg tcaagaaatg aaaaaagcca ctatcgttga agatggctat
    32041 atagccatca aagacggcct cattgtggct cttggttctg gtgaaccaga tgctgagctt
    32101 gtcggtacac agactattat gcgttcttat aaaggtaaaa ttgcaacgcc tggtattatt
    32161 gactgtcata cccatttggt ctatggtggc agtcgtgaac atgaatttgc caagaaatta
    32221 gcaggggtgt cttacttgga tattttagct caaggtggtg gtattttaag cacggtgagg
    32281 gccactcggt cagccagctt tgacaacctt tatcaaaaat ccaagagatt gctagactac
    32341 atgttgcttc atggagtgac tactgtcgaa gcgaaaagtg gctacggcct tgattgggaa
    32401 acagaaaaac gccaactgga tgttgttgct gctttagaaa aagaccatcc cattgatttg
    32461 gtgtctacgt ttatggcagc ccatgcgatt cctgaagaat acaaagggaa tcctaaggct
    32521 tatctcgatg tgattatcaa ggatatgctt cctgttgtta aagaggaaaa tctggcagaa
    32581 ttttgtgata ttttctgtga aaaaaatgtt tttacagctg atgagtctcg ctatctgtta
    32641 agcaaagcca aagaaatggg cttcaagctt cgtattcacg cagatgaaat tgcgtctata
    32701 ggcggagttg atgtcgcagc agagctcagc gcagttagtg cagagcattt gatgatgata
    32761 acagatgatg gtatcgctaa gttgattggt gctggtgtta ttggtaattt gcttccagcc
    32821 accaccttta gtttgatgga agacacttat gcccctgctc gcaaaatgat cgatgctggc
    32881 atggccatca ccctctcaac agatagtaat ccaggcagtt gcccgactgc taacatgcag
    32941 tttgtgatgc aattaggttg ttttatgtta cgtttaacac cgattgaagt cttaaatgct
    33001 gttaccatta acgcggccta ctctgtcaat cgtcaggaga gagttggtag tttgacagtt
    33061 ggtaaagaag cagatattgc catttttgat gccccaaata ttgattaccc attttatttc
    33121 tttgccacca acttgattca ccaagtctat aaaaaaggac aactcacagt tgaccgaggt
    33181 cgtattcttt aaaaaattta aaaaagaagc tttgagcgtt agctcaaaac ttcttttaaa
    33241 tatgctgttt tattgacgaa tcaagtagtc aaaggcaccg atggcagcag tagcaccaga
    33301 ccccatggaa ataatgattt gtttataagc tgaatcagta cagtccccag cagcaaagat
    33361 accaggaata ttggttgacc catgtttatc cacaatgatt tctccgcggt cggttaggtt
    33421 gacaccacta tctttgagcc aagctgtgtt tggaacaaga ccaatttgaa caaagacccc
    33481 ttcaaggtca aggtgtttgt cttcaccgct atcacgctca gtgtagttaa gacctgtaac
    33541 atggtcctct ccaacaatgt ccttagtagc aacatttttg atgatggtca tattgttagt
    33601 cttagctgcg cggtcttgaa gcactttgtc agctttaagt tcaggcaaga attctaaaac
    33661 gtaaacgtgt ttagcaagac cagccaagtc aagggccgct tctaatccag agttcccacc
    33721 accgataaca gcaacatctt tgccttcaaa gagaggaccg tcacagtgag ggcagtaagt
    33781 caccccttta ttacggaatt catcttcacc aggaacatta atgttacgcc atttggcccc
    33841 aagagctaag atagcagttt tggcttgtag aaccgcacca ttagctagag taacctcgat
    33901 gttttctttt ttctcaatag aagtagctag ttgtgctttg ataatatcaa catcataaga
    33961 cttagtatgg gcctccactt cggccattaa ttttggtcct tcagtgtaaa gggtaccaat
    34021 catgttttcg atgccgaccg tttccatgac ctgaccacca aaggtttcag caagtaaacc
    34081 tgtttttagt cctttacgag ctgcatagat agcagcgcta ttgcccgcag ggccaccacc
    34141 aataacaagg acatcataga ggcctttatc agcaaaggct tcctcagaaa gtgggccagc
    34201 gatttgttct aagagttgct caatggtagc gcgaccagaa gtgaattctt ccccgtctaa
    34261 aaagacagta gggacagaca taatgccttt tgctttcact tcatcttgga acatgccgcc
    34321 ttctaccata gtgtgtgaaa tcttgtcgtt caagacggac ataatgttta aagcttgaac
    34381 aacatctggg cagttatggc aggttaagct gacataagtt tcaaaatgca acggacggtc
    34441 aatggccttg atgcgatcaa taacatcttg atccactttt ggagcacgtc cagatacttg
    34501 caagagagca agaataaagg acgtcaattc gtggcctaaa ggaagaccag caaagacaac
    34561 cccactaccg tgaccttttt tcgcaacctt aaagcttggt tgtcggtcta aagtgatgtt
    34621 ttcaatagaa atacgctcag acatagcagc tatttcttcc acaaagtctt tgactttttg
    34681 agactgctca ttgtcaccaa gggaaacttg caaaacaaga tcagcttcta acagggtgag
    34741 gtattgggca agttgttctt taatatcagg acttaatgcc atagctttcc tcctaaaatt
    34801 tattaaattt taccaactaa atcaagactt ggtgtcaaag tttcagcgcc ttctttccat
    34861 ttagctggac aaacttcacc tggatgttta cggacgtatt gggcagcgtg aattttatca
    34921 atcaaggtgc tagcgtcacg tccaatacca tcagcattaa tttccatcat ttggataata
    34981 ccatctggat caacgataaa tgttccacgt tgagcaagtc cgtcttcgcc aagcacttca
    35041 aaggcttgtg aaataaggtg tgaagggtca ccaatcatag ggtatgtgat agtgccaacc
    35101 acatctgaat catcatgcca agctttatga acaaaatgag tatcagtaga gacagaataa
    35161 acttctacac caagagattt cagtgtttcg tattgctctt gaaggtcacc gagttcagtt
    35221 gggcaaacaa atgaaaagtc tgctgggtag aaacaaaaaa ctgcccattt tcctttaacg
    35281 tcttcatttg taacagtgat gaattttcca tcgtgataag cttgagctga aaattcagca
    35341 atttcttttc caattagaga catatagttg tcctcctttt ttatagtttt atacttgtat
    35401 tataaaagaa caacaagatt atgtctactc agaaaccctt gattttactg ggaaatcagc
    35461 gattattttc tgacaattaa gttgtgaaat aaatcacatt aattaaaatg attctaaata
    35521 agctgaagat gccgttaaa
//
LOCUS       DAUGQX010000019        33334 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUGQX010000019 DAUGQX010000000
VERSION     DAUGQX010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33334
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.019"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            76..258
                     /locus_tag="VIA51_000841"
     CDS             76..258
                     /locus_tag="VIA51_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8682796.1"
                     /translation="MLTYDEFKQAIDNGYIAGDTVAIVRKDGQIFDYVLPHEKVKNGE
                     VVTKEKVEEVLVELSR"
     gene            789..2651
                     /gene="cadA"
                     /locus_tag="VIA51_000842"
     CDS             789..2651
                     /gene="cadA"
                     /locus_tag="VIA51_000842"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEQ8682797.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTYILEKVQDLSAFEETIQVEEKQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRTM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(2951..3886)
                     /locus_tag="VIA51_000843"
     CDS             complement(2951..3886)
                     /locus_tag="VIA51_000843"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEQ8682798.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIKDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            4125..4820
                     /locus_tag="VIA51_000844"
     CDS             4125..4820
                     /locus_tag="VIA51_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEQ8682799.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            4927..5448
                     /locus_tag="VIA51_000845"
     CDS             4927..5448
                     /locus_tag="VIA51_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEQ8682800.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            5609..6151
                     /locus_tag="VIA51_000846"
     CDS             5609..6151
                     /locus_tag="VIA51_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682801.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            6275..7054
                     /locus_tag="VIA51_000847"
     CDS             6275..7054
                     /locus_tag="VIA51_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEQ8682802.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFVTNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            7853..8449
                     /gene="recR"
                     /locus_tag="VIA51_000848"
     CDS             7853..8449
                     /gene="recR"
                     /locus_tag="VIA51_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEQ8682803.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            8550..9596
                     /locus_tag="VIA51_000849"
     CDS             8550..9596
                     /locus_tag="VIA51_000849"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEQ8682804.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            9787..11178
                     /locus_tag="VIA51_000850"
     CDS             9787..11178
                     /locus_tag="VIA51_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEQ8682805.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            11258..11953
                     /locus_tag="VIA51_000851"
     CDS             11258..11953
                     /locus_tag="VIA51_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEQ8682806.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLFVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYFGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLALAFSKEK"
     gene            12201..13745
                     /locus_tag="VIA51_000852"
     CDS             12201..13745
                     /locus_tag="VIA51_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEQ8682807.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            14052..15671
                     /locus_tag="VIA51_000853"
     CDS             14052..15671
                     /locus_tag="VIA51_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8682808.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            15799..17799
                     /locus_tag="VIA51_000854"
     CDS             15799..17799
                     /locus_tag="VIA51_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEQ8682809.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTIQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(17823..18101)
                     /locus_tag="VIA51_000855"
     CDS             complement(17823..18101)
                     /locus_tag="VIA51_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEQ8682810.1"
                     /translation="MTTKKAYMYVLECVDKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(18091..18867)
                     /locus_tag="VIA51_000856"
     CDS             complement(18091..18867)
                     /locus_tag="VIA51_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEQ8682811.1"
                     /translation="MIKAILKEGERIDQLFSSDVGIIQNKDVFSYSIDSVLLSRFPKM
                     PSKGLIVDLCSGNGAVGLFASTRTKAAIVEVELQERLADMGQRSIQLNQLEDQVTMIC
                     DDLKNLLNHVPRSGVDLMLCNPPYFKSHESSKKNVSEHYLLARHEVTTNLEEICQVAR
                     HALKSNGRLAMVHRPDRFLEIIDSLRANGLAPKRVQFVYPKLGKSANMLLIEAIKDGS
                     IEGMTILPPLVVHKENGEYTDHIFEIYFGAASKGKPNHDH"
     gene            18985..19725
                     /locus_tag="VIA51_000857"
     CDS             18985..19725
                     /locus_tag="VIA51_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEQ8682812.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKLAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRIDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            19925..20587
                     /locus_tag="VIA51_000858"
     CDS             19925..20587
                     /locus_tag="VIA51_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEQ8682813.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            20568..22811
                     /locus_tag="VIA51_000859"
     CDS             20568..22811
                     /locus_tag="VIA51_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEQ8682814.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVFFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPIQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
                     FLTYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGRTS
                     WHLETVR"
     gene            22882..23922
                     /locus_tag="VIA51_000860"
     CDS             22882..23922
                     /locus_tag="VIA51_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEQ8682815.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFDQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKIDAARDLIHDLRLSGEDDIKLIAIMLGQFRLFLQLTILARDVKNEQQL
                     VISLSDILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            24019..24624
                     /locus_tag="VIA51_000861"
     CDS             24019..24624
                     /locus_tag="VIA51_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEQ8682816.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQTLINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIVNWKKVSELYQAAK"
     gene            24791..25018
                     /locus_tag="VIA51_000862"
     CDS             24791..25018
                     /locus_tag="VIA51_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682817.1"
                     /translation="MLRKKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGERQQTA
                     DLKMRKRLEKLFKNRYLKNLKRLSKLLWMQI"
     gene            25003..25251
                     /locus_tag="VIA51_000863"
     CDS             25003..25251
                     /locus_tag="VIA51_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682818.1"
                     /translation="MDADLAQMDVLGLYYDDNHLSLVNTVKAYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            25248..25838
                     /locus_tag="VIA51_000864"
     CDS             25248..25838
                     /locus_tag="VIA51_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEQ8682819.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSIPDMQEYSLVYSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTAYYLQVLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLIALYSSGL
                     GGATQASEEVNGLGYVQLVQLPYVINEWYRGNLNMI"
     gene            complement(25952..27172)
                     /locus_tag="VIA51_000865"
     CDS             complement(25952..27172)
                     /locus_tag="VIA51_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8682820.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(27179..28207)
                     /gene="queA"
                     /locus_tag="VIA51_000866"
     CDS             complement(27179..28207)
                     /gene="queA"
                     /locus_tag="VIA51_000866"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEQ8682821.1"
                     /translation="MNTNNFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            28409..29113
                     /gene="nagB"
                     /locus_tag="VIA51_000867"
     CDS             28409..29113
                     /gene="nagB"
                     /locus_tag="VIA51_000867"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEQ8682822.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDV
                     EAEAKRYNQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIEDVPKQAISMGIASIMKSEMIVLLAFGQEKADAIKGMVFGPITEHLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            29232..29948
                     /locus_tag="VIA51_000868"
     CDS             29232..29948
                     /locus_tag="VIA51_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8682823.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            30243..31205
                     /locus_tag="VIA51_000869"
     CDS             30243..31205
                     /locus_tag="VIA51_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor"
                     /protein_id="HEQ8682824.1"
                     /translation="MTKILTALDDKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            31218..33023
                     /gene="pepF"
                     /locus_tag="VIA51_000870"
     CDS             31218..33023
                     /gene="pepF"
                     /locus_tag="VIA51_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8682825.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFA
                     GHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFILLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMEKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
BASE COUNT        10153 a         5827 c         6895 g        10459 t
ORIGIN      
        1 attaaattta aacgaccttt aaatttaatt atattatttc ctgtaaaata cgaataaata
       61 agtaggaggg taaaaatgct aacatacgac gagtttaagc aagcgattga caatggatat
      121 atcgcaggcg atacagtagc gatcgtgcgt aaagacggac agatttttga ttatgtgttg
      181 ccacatgaga aagtaaagaa tggagaagtt gtgactaagg aaaaagtgga agaggtgctg
      241 gtggagcttt cgagataagt attttctttg ccccctgaga agtagtttta ttaaaggggt
      301 aaataggggg cataagttta aaacttacat agttgattcg aagcaattat ataaagtttc
      361 gttattttgt agctttataa aatcaaagtt tattatatta tatgtgcaca atattaagta
      421 atctttaaaa gacgctgtta aataattcgt ctagaaaaat cttgttgcta tcgatgttta
      481 ttgatagcga caaggttctt tttttatatt tggggcataa agttagtagt tttctcttca
      541 gttaagccaa gttctaaagc atgcactcta taatggtcag tcatccttct attagtatat
      601 catttccgca ggtaggggga gtttttttca tatttgcaaa tagttgaagt taggattttt
      661 gaaagcaaaa ggtaagttta aaaaagttta tttagaatgt ttctaaatta cttgacttat
      721 ttatttagaa ttattataat taatatatct taaagattga ataactttta attgcgaggg
      781 aactaaaaat gacaatcaga caatggatgg cagaccatct tcatttgatg gagactttag
      841 cgtgtttggt attaataata attggcctag cctttttaca ctcatttcca caagtggctt
      901 ccgctatttt cattacagcc ttcttgattg gaggatatgc gtctgcaaaa acgggtatat
      961 tggatttggt gaagaacaaa cacttgtcag tggatatttt gatgattttg gcagctatcg
     1021 gtgctggaat tatcggctat tggctggagg gtgctctgct tatttttatc ttttcgttgt
     1081 ccaatacgct tgaagaaatg gccatggaaa aaagtaagga tgctatttca gccttgatgt
     1141 ccttgacgcc agatacagct cgtcaatacc aagaagatgg ccatatttta gaagttgaga
     1201 ccagatcctt gagtgttggt gaccgtttac aagttcgtaa aggcgaagct gttccaattg
     1261 acgggcagtt gcttagtcct tttggtcaat ttgatgaatc tatggtcact ggtgagccta
     1321 tcactgttga taaggcagaa ggccaggatc tgattggggg aaccattaac caaggacaaa
     1381 ccatagatat gttggttact attgaaaatg acgatactct ctttgccaag attattaatc
     1441 tggtggaatc tgcccaagaa aagaaaagca aaaccgccac ctttatcgaa agcttagaag
     1501 atggttatgt caaatttgtg ctcgtcctta ttcctgcctt tatcctcttt agccactttg
     1561 tgctttcttg gacttggttg gctgcttttt accgagggat gattctctta acagtagctt
     1621 caccatgtgc cctaattgcc agttccacac ctgctagctt ggctgctatt tctcgtgcag
     1681 ccagaaaggg attgattatc aaaggagggg atattgtcga taacatggga gatattaagg
     1741 ctgttgtcat ggataaaacg ggaacgctca cccaaggaaa accttctgtt gtgaatgctc
     1801 attatttgga agatgagttg ctcgtgaata gactggtaaa aggagcagag actgctagta
     1861 cccatcctat ttctaaagcc cttcttgaat acactgaaaa attggagcca ctgacctttg
     1921 accacttaga agaaatttct gggaaaggtt ttcagggctt ctatcaaggg caagaatggc
     1981 gaattggcaa gaaaacctac attttggaaa aggttcaaga cctatcagct tttgaagaaa
     2041 ctattcaagt ggaagaaaaa caagggaaaa ccctaatctt tgtttcacgt gaccatcaat
     2101 tgatagctta ctatgccctc ttggatgata tcaaaataga atcaaaacgt gctattaagt
     2161 ctcttcatgc catgggaatc aaaacagtca tgttaacagg tgaccaagaa cgaaccgcca
     2221 attatgtggc acaaaaactt ggtattgatg aagtggtagc caactgtatg cctcaagata
     2281 aggtggctaa gttagcagaa ttaaagacta aatatggttt tgtggctatg gtaggagatg
     2341 gtattaatga tgctcctgcc cttgctcaag cagatgtttc ttatgctatt ggatcaggaa
     2401 cagatattgc aatggaaagt gcagacagtg tgattatgga tgacttgact cgtattccat
     2461 tttcgattca actttcccgc acaatgaaga ccattatcaa acaaaatatt gtttttgcct
     2521 tatctgtgat taccttattg attttagcca atgtttttca ggtagttaac ttgccgcttg
     2581 gtgttgttgg acacgaaggc tcaacgattt tagtgatttt aaatggcttg cgtttacttt
     2641 cttttaaata atttagaaac ttgcttgaaa acttgaaagt gtttataata atagtaagac
     2701 ttatgaaaga gaaaaccgcc gtatgtttac tattatgatc attggtttag ctgtattttc
     2761 aataattaaa atcattctat ttttctattt ttatcagcaa tttgagcgca agcaaaaaag
     2821 aaaagttgaa tcaaacaacc agcaaagaca gtcccaagaa agtgacgctg tcccttcaaa
     2881 aaaattccca ttttaaaaag cttggaaagt gtacaaagtg cacatttcca agcttttttg
     2941 actattaagg ttaatctttg taacgtaagt tcccacgaaa atcgtctaag ctttggtagc
     3001 ctttttctac cataatcgtt ttaagttcct tagtgacccg ttcaaagata gctggccctt
     3061 cttgatgaag ggctgtccca atttggacca tgctggcgcc acaaagaata tgttcaaagg
     3121 catcgcgtcc tgttttaact ccccctgtac caataatgtg gatagaaggt tttaagcgtt
     3181 tgtaaaacgc atggacattg gctagagcag taggtttgat gtaatctcca cctataccac
     3241 caaagccatt tttaggcttg atgaggactt gttcatcctt aatgaccagc ccatttccga
     3301 tagaattgac acagttaaca aaggaaaggg ggtatttatt gaaaatcgca gccgcttgat
     3361 caaaatgcac aatgtcaaaa taaggaggta atttgatacc aagaggttta gtgtaatagg
     3421 taaagatgtt ctctagaagt tgatcagtgg tttcaaaatc ataagcaatc tgtggttttc
     3481 ctggaacgtt agggcaagaa aggtttagtt ccactagacc ctcataatct gaagccatga
     3541 tggcttttaa aatggtttcg gtttcagtag gagatagccc gacaacggag agaaagtgag
     3601 gtttatgttg cccggttttg gcaagatcac tgacaaagtc taagtagtag cgaaaaccat
     3661 tattagggag tcccattgaa ttgatagaac caagacgagt atctgcgtag cgaggttctg
     3721 gattacctgg acgaacttca agcgtccctg ttttggtgac aaaggaagcg gcttgagact
     3781 tttcaacctc cataagctct tcttttgtca tgcagtaaac accagcagca ttcatcaaac
     3841 agttatcaaa agagaaatga ccaatttgtg tagcagtaga aaccattatt tcctccatat
     3901 tttagacaaa ttttttctat tctaccacta ggcatgaata atagcaagct atttttacaa
     3961 aaatgtaaat atattactgt tattgacgaa catttgaaat tttcatgata gtcacattat
     4021 gattttcaat aaagtcagaa tagactagct tttttgctat attttttgta aaataggaac
     4081 tgtaaaaagg tagcaacctt taaattaaaa ggagatatta actcatggta aaattggttt
     4141 tcgctcgcca cggtgagtca gaatggaaca aagctaacct cttcactggt tgggcagatg
     4201 ttgatctttc agaaaaaggg acacaacaag cgattgatgc aggtaaattg atcaaagaag
     4261 caggtattga atttgacctt gctttcactt cagtattgac acgtgctatc aaaacaacta
     4321 accttgccct tgaaaatgca ggtcaattgt gggttccaac tgaaaaatca tggcgcttga
     4381 acgagcgtca ctatggtgct ttgactggca aaaacaaagc tgaagctgca gaacaatttg
     4441 gtgatgaaca agttcatatc tggcgtcgtt catacgacgt gttgccgcca gctatggcta
     4501 aagatgatga gtattcagca cacaaagacc gtcgttatgc tgatcttgac ccagccctta
     4561 ttccagatgc tgaaaactta aaagtaactc ttgaacgcgc aatgccttac tgggaagaaa
     4621 aaattgctcc agctcttctt gacggtaaaa acgtctttgt tggcgcacat ggtaactcaa
     4681 tccgcgctct tgtgaaacac attaaaggtc tttcagatga cgaaatcatg gatgtggaaa
     4741 ttccaaactt cccaccactt gtttttgaat tagatgaaaa acttaacatt gttaaagaat
     4801 actaccttgg tggtgaataa cttaaaaacc agactttggt ctggtttttt ggttctatat
     4861 cctaagaaga aagaaaaccc tgcttaaaaa tatgatatga tagaaataaa aaaggataga
     4921 tagattatga aagcagaaga tcgtcgtcaa aaaattattg agtgcttaaa tagtgaacaa
     4981 aaagctgtat ctgctactcg tttaggtaag ttattaggag tgagtcgcca agtaatcgtt
     5041 ggagatatag ctcttcttcg agctcagcag attgatatta tttcgactcc aaaaggttat
     5101 attatgtcaa cagcacttta tagtcaccaa ttttgtgcac gtattgtgtg ccaacataat
     5161 gtagaagaaa ctaaaaaaga attagaaatt attttagctc atcaagggat tattacgacg
     5221 gtagaggtag aacatcctat ttacggtatg ataacagccc ctttaaatat taagacacac
     5281 tctgatgtaa ctaatttcat gtccaaactc agtcaatcta aagcagagtt attgtcttcg
     5341 ttgacagaag gactacatag tcacttaatt tcgtgtccta gtcaagaagc ctttttagct
     5401 attaagcatg atttagaatt agcaggtatc ttatacaaag gaatataact atagtatatt
     5461 atgccattga tggttgttat gaataccatg ctaaaatatt ctattgatta tttatcagca
     5521 acaaggtatc gtttaaaaat accaaaagat acaggtgtct tgatagttat tggtttttaa
     5581 ggtatactat ttttgaaaag gagataaaat gactaaaaaa ccaacacaac taatagctta
     5641 tacctctatt ttggtcgcat ttgcgatttt gattccgata atcatgcctc ttaagcttat
     5701 tattggacca gcttccttta ctctggcgag ccatgttcct ttgtttttgg ctatttttat
     5761 gtcgattcca gtagcaattt tggtcgctct tggtaccaca ttaggttttt tattagctgg
     5821 actaccttta attattgttt taagagcact ctctcattta ttgtttgcta ttttggcagc
     5881 gtggtggtta agtagaaaac cacaactgat gacatcggca gtaaaatgtt ttagttttgc
     5941 gtttttcatt aatgtcattc atggcttggc tgaattttta gttgtctata ttttaacagc
     6001 aaccacagca acttctatgt cttatttttg gtctatgcta ggcttgattg gcttaggttc
     6061 gcttattcat ggcatattgg atttctatct tgctttagtt ctatggcgtt ttttagcaaa
     6121 aaacttaaaa cttcccacca taaatgccta agactaaaat agagatagtt atatgataat
     6181 gacgagccct ttcttgttga aagggcttgc attttttagg aaaattgata tactaaagtg
     6241 tgtgtttgtg aatacagtaa caaaaggaga tatcatgaaa acaccagaac agattttaga
     6301 agcaactatt catattgggg aacataaggt taccaaaact tttttggcta aatctatctt
     6361 aggctttatt ggtggagcga tgattagcct tggttattta ctatacgtga gaattgccgc
     6421 cagtggttta gaaacttttg gtgctttttc cagtatcgta ggagcttgtg cttttccgat
     6481 tggtctaatt attattttaa tggcgggtgg agaattaatt acagggaaca tgatggctgt
     6541 ttctgcagct ttgttggcca aaaaaattaa gtttagcgag cttgccaaga attggcttat
     6601 cattaccttg tttaatgtga ttggagctgt ttttgtagct tttgtgtttg gtcattttct
     6661 aggcttaaca tcagctggta tttttaaaga agaagtgatt gaggtggccc atgctaaaat
     6721 agcagcgagc cctttgcagg cactagtatc aggaattggt tgtaactggt ttgttggttt
     6781 ggccttgtgg ctatgctatg gggcaaatga tgctgctggt aaattccttg gtacttggtt
     6841 tcctgtcatg acctttgtag cccttggttt tcagcatagt gtagcaaatg cttttgtcat
     6901 tcctgctgct atttttgaag gaggagcaac atggttggat tttgtcacta attttatttt
     6961 tgtctatagt ggtaatatta tcggtggagc catttttgtt agttttttat attttaaagt
     7021 ttactatcat ccgcaaaaga gtaaaactca atgagaaaat atttttttag actgagggcg
     7081 tcctattctc agtcttcttt ttataattta tggtaaaata agaagcgaag tttaaaaaat
     7141 ttagctaaat aatggttagt ttattcccta aaaaaggagt attcccaaaa aatccgtaaa
     7201 aagaatttgc catgggagta gttcccaaaa taatgcagat catttagttg tctttcaaaa
     7261 atagccttga tagggtaaaa agtggacagt gatgcagcaa cagattcatc aggcgtacaa
     7321 actgtcttat ggtttgtgct tagagatttc ttaataatgc ttttggtaat acacttttag
     7381 tgaagaaagt gtagcatgaa agcttaaaga taaccatgag ttcgctttat gcactattgt
     7441 tgagaaaaat agcatagtca attgagtaaa catcatttct gcatggaatg aaacaattcc
     7501 tataaactta tatcataagg atggtttgcg gtttctaaaa aagtaacatg aatcaaaaaa
     7561 caaaagccaa atatcccaag gccaaggtaa caagtcgagt aaaaaagttt ttacttggct
     7621 aatccaaacg gttctgtcac gattcacgct aaaattggaa ctgttgagac ttgtatcaca
     7681 gacaattcag atcagacctt agtaacttac aacttaaatg tagtagctta taatacaaat
     7741 aacgaagata atattgcggt tgctgttatg tatccacata ttacgaatat atcggcaaag
     7801 atgtgagagc gctttatgtg gcgatatatg gaaaacaata aaggagaact tagtgcttta
     7861 tccaacaccc attgcaaagt taattgacag ttactctaaa cttccaggaa ttggtatcaa
     7921 gacggcgacg agattagcct tttatactat tggaatgtca aatgaagatg tcaatgattt
     7981 tgctaaaaac ttattagcag ctaaaagaga actgacctat tgttcgattt gtggaaacct
     8041 taccgatgac gatccttgtc acatttgcac agacacgagt cgtgatcaga cgaccattct
     8101 ggtagtagaa gatgctaaag atgtttctgc catggaaaaa atccaagagt atcatggcta
     8161 ttatcatgtg cttcacggct tgatttcgcc tatgaatggt gtggggccag atgacatcaa
     8221 ccttaaaagt ttaattaccc gtctaatgga tggtaaggtg agcgaagtta tcgtagctac
     8281 caatgccaca gcagatgggg aagcaacgtc catgtatatt tcacgtgtct tgaaaccagc
     8341 cgggattaag gtaactcgtt tggcaagagg tctcgcagta ggttcagata ttgagtatgc
     8401 tgatgaagta acattattga gagctattga gaatcgtact gaactttaat gatcatgttg
     8461 gtgcctttac tcgcaaagag aggttttgaa aaggctacat ctttttgtta taataaaaaa
     8521 acattcaatt cagataagaa aggttagcta tgtccaaaca aacgttagtt ctattatacg
     8581 gaggccgctc agcagaacgt gaagtctcag tgctttcagc agagagtgtg atgcgagcag
     8641 tcaactatga taagttctta gtaaaaactt attttattac tcagatgggc caatttatca
     8701 aaactcagca attttcagaa aagccatcgg aatcagaacg cttgatgaca aatgagacga
     8761 tagagctaac tcaaaaaata aaaccaagtg atatctatga agaaggtgca gttgtatttc
     8821 ctgtattaca tggacctatg ggagaagatg gctctatcca aggtttctta gaagtgctta
     8881 gaatgccata tatagggact aatgtcatgt cttctagcat agctatggat aaaattacta
     8941 ctaaacgtgt cttagaatca attggaattc cacaagttgc ctatactgtt tatattgacg
     9001 gacaagattt ggaggcttgt ttagttgaaa ctttagcaag acttactttt cctatcttcg
     9061 taaaaccagc taatatgggt tcttctgtgg ggatttccaa agcccaaaca aaagtagaat
     9121 taagaaaagc gattcagtta gccctgacct atgacagtcg tgtcttgatt gaacaaggcg
     9181 tggttgcaag agaaattgaa gttggtctcc ttggaaatga taaggttaaa tcaactctac
     9241 caggagaagt aatcaaggac gttgattttt acgactacca ggcaaaatat gttgacaata
     9301 agattacgat ggccattcca gcagatgtag accagagtat tgtgacagaa atgcgttctt
     9361 atgctgaagt agcctttaaa gccttaggtg gttgtgggtt gtcccgttgt gactttttct
     9421 tgacccaaga tggacaggtt taccttaatg aattaaacac catgccaggc tttacccaat
     9481 ggtctatgta tccactctta tgggaaaata tgggattggc ttatccagat ttgattgaag
     9541 agctggtgac actggcacaa gaaatgtttg accagcgtga gagccacctg atttaaacct
     9601 atgagatgaa taaacattga cttggatgga acggcaaaca tcgtcaagat gtgacgttcg
     9661 tccttttttt gttgctcttt atagtagagt cattaaggga gtttgacatt ttagaaattt
     9721 ttctaatgtt ttgtgctata atagatagga catcgtaaat actagtgttc ttagaaagaa
     9781 aacaaaatga aattaacctt acacgaagtg gctaaaatag ttgacgccca aaataatgtg
     9841 tctgacttag acgacgttcc tctgcatcac attgaatttg atagccgaaa gattacaaaa
     9901 ggagacctct ttttaccctt aaaaggtcaa agggatggtc atgagtttat tgatttagcc
     9961 tttcaaaatg gagctgtcgc tactttttca gaaaaagaat tgccggggaa acctcacctt
    10021 cttgttgaag actgcctaaa agcttttcaa aagctagccc attattatat tgataagatg
    10081 cgcgtggatg ttattgctgt gacaggctca aatggtaaaa cttccaccaa agatatgata
    10141 ggagctgtcc tatcaaccac ttacaaaact tacaaaacgc aaggaaatta caataatgag
    10201 attggtttgc cttacaccgt tctccacatg cctgacgata cggaaaaaat tgttcttgaa
    10261 atgggacaag atcacatggg agatattcgt cttctgtctg aaattgcaag gcctcgtatt
    10321 gcagttttaa ccttagtcgg cgaagctcat ttagaatatt ttggaagccg agacaaaata
    10381 gcccaaggca aaatgcagat tgttgacggc atgaattcag atgggatttt aattgctccg
    10441 ggagatccga ttattgaccc atatcttcca gaaaatcaga tggttatccg ttttggaaat
    10501 cagcaggaaa ttgacgttac tggtattcaa gaagacaaag atagcttaac gtttacaaca
    10561 aatgtgttag caacacctgt gtccctacct ctaccaggaa aatacaacgc gaccaatgct
    10621 atggtagcag cctatgtagg aaaactattg gcagtaacag acgaggatat tatagctgct
    10681 ttacagactg tgacgttgac aggtaatcgt acggagtgga aaaaagcagc caatggtgct
    10741 gatattttgt cagatgtcta caatgccaac ccaacagcca tgcgtctgat tttagaaaca
    10801 tttgctaaca tagcaaagaa ccccggagga aaaaagattg cagtgctagc agatatgaaa
    10861 gaacttggaa aggattcagt gatacttcat tctcagttaa ttgacagctt aacatcaggt
    10921 aatattgatc agcttgtttt ttatggggat catattaaag aattagcacg gttggcaagt
    10981 caggtttatc ctgctgagca agtacattat tttttaaaaa ctgaacaaga agaccagttt
    11041 gaagccatgg cacaatatgt tcaaaacatt cttaatccct ttgatcaaat tcttttaaaa
    11101 ggcagccact cgatgtcgct agaaaagtta gtagatcgat tagtgactga caagaattgt
    11161 gacagctatc agccttgatt tttataaaac tttcagagaa aggcttgttc tctcatgaag
    11221 attaaggtat aatgaaaaaa tatagaaagg gacgattatg gatttttttg caattgaccc
    11281 catcggactg cctcatacct cacttatctt ttacttgtcg tcactcttga tagcgctttt
    11341 gtttgttttt ttgacttttc aagcatatag gttaaaatct tatcgttatt ttttcttgtt
    11401 tttacagtta tctcaggtga ttggcttata cacatggtac gtgttaaggg ggtttccttt
    11461 agatgaagct ttgccgttgt atcattgtcg catcgctatg ttagctatct tttttctacc
    11521 tgatcgtaac aagtttaagc aattatttat ggttttgggg ataggtggaa cattccttgc
    11581 acttttatcg ccagatcttt atccgtttag attatggcat gtagcaaatg tctcgtttta
    11641 ttttggtcat tatgctttgt tagtgaatgg tttgatttac ctcttgcgtt tttacgatgc
    11701 cagtcagtta agactgctat cagtagtacg ctatttagca actgttaact ttcttcttct
    11761 gttggtcagt ttagccacga aaggaaatta tggttttgtg atggatattc cagtgattca
    11821 tacgcgtcat ttgctactta attttgtgat cgttacaagt ggcttgactt ttatggttaa
    11881 aataaccgaa tatttttacc ttaaatttgg tgaagctcaa cagctggcac ttgctttctc
    11941 taaagaaaag taggtcgttg aaaaagcact taaaatcagc tataataaga agagtctggg
    12001 atgatttcca ggctcgattt ttaaaaaaaa gacactcatt gatagcccaa gataagttat
    12061 aataccagtt ttgaagaact ttagaggcta atcgtatatg gagaaaccca atgtagccca
    12121 actcttttga taaacaagta atacctaacg aaaataactc agagaaaagc tctgccattt
    12181 tactatacaa ggaaaaaaga atgtcactta cagaagaaat taaaaaacgc cgtacttttg
    12241 ccatcatttc tcacccggat gctggtaaga cgactattac tgagcaacta ttatattttg
    12301 gtggtgaaat tagagaagca gggacagtaa aaggcaaaaa atcaggtacg tttgcaaagt
    12361 ccgactggat ggatattgaa aagcaacgtg gtatctctgt tacttcatct gttatgcaat
    12421 ttgattacgc gggtaaacgt gttaatattt tggatacacc tggacatgag gatttctcgg
    12481 aagatacata ccgtacctta atggctgtgg atgcggctgt catggttgta gattcggcta
    12541 aaggtattga ggcgcaaacg aaaaaacttt ttgaagttgt caaacatcgt aatattcctg
    12601 tcttcacctt tattaacaag ttagaccgtg atgggcgtga gcctttagaa ctcttggaag
    12661 aattagaaga agttttaggg attgcttctt atccgatgaa ctggccgatt ggtatgggac
    12721 gcgcctttga gggcttatat gatttacata ataaacgttt agaactctat aagggagacg
    12781 agcgttttgc aagtattgaa gacggtgatc agctgtttgc caataatccc ttttatgaac
    12841 aagtcaaaga agatattgaa cttcttcaag aagcaggtaa tgacttttca gaacaagcta
    12901 ttcttgatgg tgacctaact ccagtctttt ttggctctgc ccttacgaac tttggagttc
    12961 agacttttct tgatactttc ttggagtttg ccccagaacc tcatggtcac aagactacag
    13021 aaggtaatgt tgttgacccc ttagctaaag atttttcagg ttttgtcttt aaaattcaag
    13081 ctaacatgga ccctaaacac cgtgaccgta ttgcttttgt gcgtattgtt tctggtgaat
    13141 ttgagcgcgg tatgggagtt aatttgacac gcactggcaa aggcgctaag ctctccaatg
    13201 ttactcaatt tatggcagaa tcacgggaaa atgtgacgaa tgctgttgct ggggatatta
    13261 tcggggttta tgatacagga acttatcaag ttggggatac cttaacagtt gggaaaaata
    13321 aatttgaatt tgaaccctta ccaactttta ccccagaaat cttcatgaag gtttctccga
    13381 aaaatgttat gaagcagaaa tccttccaca aaggtattga acaattagta caagaaggag
    13441 caattcagct ttataagaat tatcagacag gcgaatacat gctgggtgct gtgggtcaac
    13501 tgcagtttga agtctttaaa catcgtatgg aaggtgaata caacgctgaa gttgtgatga
    13561 caccaatggg taaaaagact gttcgctgga tttcagaaga tgatttggat caacgcatgt
    13621 cttcaagccg aaacatttta gctaaggatc gttttgacca accagttttc ctatttgaaa
    13681 atgattttgc ccttcgctgg tttgcagaca aatacccaga tgtcacttta gaagagaaaa
    13741 tgtaattgaa acatgatttt caacagtcta acgttttgga gatcaattta ctgagcaact
    13801 ttttaaaaga aatgagtggc tagttatctc ttttgcagat ttaagattct atcaaaaaac
    13861 gatatcttca caactgtaag catatttatg atttagcgga taatcgtgaa agcgtgttat
    13921 tgcttatatt agccttattt cctatctttt tgattctaat tgtgttacac tagttaggtt
    13981 gttaatcaaa cgacgaaaat taaaaggttt ataaggcagc ttcgcactgc ctttttagaa
    14041 aagagaaaca attgaaattt acagaattta acttatcaca agacatccaa tcagctgttg
    14101 ttaccgctgg ttttgagaaa gcatctccta tccaggaaat gacgattcct ctcgcactag
    14161 aagggaagga tgttattggt caagcacaaa caggaactgg taaaacagca gcgtttggtc
    14221 taccaacctt gaataagatt cgtactaacg aaaatatcat ccaagcattg gtcattgcac
    14281 caacgcgtga attggctgta caaagtcagg aagaattgtt ccgttttgga cgtgaaaaag
    14341 gggttaaggt tcgctctgtt tacggtggat caagtattga aaaacaaatc aaagccctta
    14401 aatcaggtgc ccacattgtc gtgggaacac cgggtcgctt gttagatttg attaagcgca
    14461 aggctcttat tttagatcat gtggaaacct taatccttga tgaagcagat gaaatgctta
    14521 acatgggatt cttggaagac attgaagcta ttattagtcg tgtcccagca gaccgtcaaa
    14581 ccttgctctt ctccgcaacg atgccggcac ctattaaaca aatcggggtt aaattcatga
    14641 aagaccctga acatgttcaa attaagaaca aagaattaac aaacgtcaat gttgatcaat
    14701 actatgttcg tgtgaaagaa caagaaaaat ttgatactat gacccgtctg atggatgtta
    14761 accagccaga attatccatc gtttttgggc ggactaagcg ccgagttgat gaaattacac
    14821 gtggcttgaa acttcgtggt ttccgtgccg aaggaatcca tggtgatctt gaccaaaata
    14881 aacgcttacg tgttatccgt gatttcaaaa acgaccaaat tgatattctt gttgccactg
    14941 atgtagcagc gcgtggcctt gatatttcag gagttaccca cgtttataac tacgatatta
    15001 cccaagatcc agaaagttat gttcaccgta ttggtcgtac aggtcgtgcc ggtaaatctg
    15061 gtgagtctat cacttttgtc tcaccaaatg agatgggcta cctctcaatg attgagaact
    15121 taacgaaaaa acagatgaaa cctcttcgtc cagcaactgc tgaagaggcc tttcaagcca
    15181 agaaaaaagt agccctcaag aaaattgaac gcgactttgc ggatgagact attcgttcaa
    15241 actttgataa attcaaaggc gatgctgtcc aattggctgc cgaattcact cctgaagaat
    15301 tagctttata tattttgagc ttaacggttc aagatccaga tagcttaccg gaagttgaaa
    15361 ttgcacgtga aaaaccatta ccattcaaat atgtgggtgg tggtcacggc aataaaaatg
    15421 gcaaaggtgg tcgtggacgt gacaaccgta accgtggtga tcgccgtggc ggctatcgtg
    15481 gtgaccgtaa cagagatgag cgtgatggtg accgtcgtcg tcaaaaacgt gataagcgtg
    15541 atggtcacga tggcagtggc aaccgcgatt tcaaacgtaa atcaaaacgt aatagtaaag
    15601 actttttcaa taaagagaaa aaatcaagtg ctaaaaatac tggttttgtg attcgtcaca
    15661 aaggtgaata agcttaaaga gagttgatga gagtcagctc tttttaattt tctgaaaaag
    15721 ttgcttttat aatggaatct gttataatgg tttcagttat ttttgtgata atttttaaaa
    15781 aattaggagg agtataagat gtctgatagc catcttactg cctttgacaa agcttcaaaa
    15841 gcaggtttta ttattgcttt aggtattgtt tatggagata ttggaacaag ccccctttat
    15901 acgatacagt ctctagttga aaatcaagga ggggttaatc aggtttctga atcctttatt
    15961 ttaggatcaa tctctttaat tatttggaca ctgaccttaa tcacaacaat caagtacgtt
    16021 ttgattgctc taaaagcgga taaccaccat gaaggtggga ttttttcttt attcaccttg
    16081 gtacgtaaaa tgtcaccgtg gctcattatt ccggcgatga ttggaggtgc aacacttttg
    16141 tctgatgggg ctcttacacc tgcggtaaca gttacttcag ctattgaggg cttgaaagcc
    16201 gttcctggtc tgagtcacat ctaccaaaat caaaccaatg tcattatcac aactctagtg
    16261 attttaatag tcttgtttgg tattcagcgg tttggaacag gttttattgg taaaattttt
    16321 ggaccagtta tgtttatctg gtttagtttt ctaggtgtta gtggtttttt taatacgttg
    16381 gggcatctgg aaattttcaa ggctatcaat ccttactatg ctctgcattt gctgtttagt
    16441 cctgaaaacc atcgtgggat ttttatcttg gggtccattt ttcttgcgac aacaggagct
    16501 gaagctcttt attcggattt aggacatgtt ggtcgaggaa atatttacgt gagctggccc
    16561 tttgttaaga tgtgtattgt gttgtcttac tgtggccagg ctgcgtggat tttagcgaat
    16621 aaacactcag gtattgaact aaaccctttc tttgctagtg tgccatcaca attaagagtt
    16681 taccttgtta gtttggcaac cttggcagct attattgcct cacaggctct tatttcaggc
    16741 tcctttacct tggtttcaga ggccatgcgt ttgaaaattt tccctttgtt tcgtgtgact
    16801 tacccagggg caaatttggg gcaattgtat attcctgtca ttaactggat tttatttgca
    16861 gtgacctctt gtactgtttt ggcttttaga acatcagccc acatggaggc agcttatggt
    16921 cttgctatta ccatcaccat gttgatgaca acaatcctct taaagtatta cttaatcaag
    16981 aaaggaacga gacccatctt ggctcattta gtgatggctt tctttgccct tgtagaattc
    17041 attttcttct tggcttcagc tatcaaattt atgcacggtg gctatgcggt tgttatcttg
    17101 gcacttgcaa ttgtctttgt catgtttatc tggcatgcgg gcacacggat tgttttcaag
    17161 tatgtgaaat ctcttaattt gaatgattac aaggagcaga ttaaacaact tcgtgacgac
    17221 gtttgttttg acctctacca aacaaatgtt gtctacctat ccaatcgtat gcaggatcat
    17281 atgattgacc ggtctatttt atactccatt ttagacaagc ggccaaaacg cgctcaagtt
    17341 tattggtttg taaatgtcca ggtaactgat gaaccttata cagctaagta caaggtagat
    17401 atgatgggaa cggattatat ggttcgagtc aacctttatc ttggttttag aatgccacag
    17461 actgtgccac gctatttgcg cacgattgtt caggatttga tggaaagtgg ccgtttaccc
    17521 aaacaagaac aggaatatac catcacacct ggtcgtgatg ttggtgattt tcgctttgtt
    17581 ttaatagaag aacgggtctc caatgcacgt caattgagta actttgaacg ctttattatg
    17641 cagactaagg caagcattaa acatgttacc gctagtccaa tgcgttggtt tgggcttcaa
    17701 tattcagaag taacccttga agtggttccc ttgattctat cagatgtctt gaagttacca
    17761 atcaaagaat tggtgcctgt ggaagacagt gaagcataaa aaaatcattg agatgataag
    17821 tctcaatgat ttttcttttc tttttgatga gtagcaatat aggccaattt ctggcttctt
    17881 gtttttcgtt ttttaaagag tgcttcagcg ctcatcgcag cctctttgct atcaaacact
    17941 tcgtaataaa gtaaagaaac aggtaaccgg tagcgagtat atttagcccc ctttcctgcg
    18001 ttatgtgtag ctaagcgttt tttcaaatca gttgtataac cagtgtagag ggttttatca
    18061 acacattcta acacatacat ataagctttt ttagtggtca tgattaggtt ttcctttgga
    18121 agcagcacca aaataaatct caaaaatatg atcagtgtat tctccgtttt ccttgtggac
    18181 aactaaagga ggtaaaatag tcatcccttc aatagaaccg tctttgattg cttcaataag
    18241 taacatatta gctgatttac ctaatttagg atagacaaat tgtacccttt taggggcaag
    18301 accattagct ctaaggctat ctataatttc caagaatcga tctggtcgat gaaccattgc
    18361 cagacgacca tttgatttaa gggcatgacg ggctacctga caaatctctt ctaaattagt
    18421 ggtcacttca tgacgagcca gtaaataatg ttcagagacg ttcttcttag aactttcgtg
    18481 acttttaaag taagggggat tgcagagcat caaatcaact cctgaacgtg gcacatggtt
    18541 taggaggttt tttaaatcat cacaaatcat ggttacttgg tcttccagtt gattgagctg
    18601 gatagagcgt tgtcccatat cagcaagccg ttcttgtaat tctacttcaa cgatggctgc
    18661 cttggttcta gtgctagcaa ataagccaac cgccccattt cctgagcaca aatccacaat
    18721 taaccctttg gaaggcatct tggggaagcg ggataagagg acgctatcaa tagagtaact
    18781 aaagacatcc ttgttttgaa taatgccaac atcacttgaa aagagttgat caatacgttc
    18841 gccttctttt aagattgctt ttatcatacc tgttatttta acataaaata ggcttgaggt
    18901 gaatgtttga agagtgattt tgactttcga aaagtcagct ttcgtgatac aataagtaag
    18961 attattctat taaaggagaa gcctgtgttt tacgcttact tacgcggttt agtagtcttt
    19021 ttattatggg ttgtcaatgg caatgcccac taccatcatg aagaaaagat gttagatgct
    19081 tctgagaatt atattctggt agcaccccat cgaacctttt gggatccagt ttacatggca
    19141 tttgcagcac gtcctaagca gtttattttt atggctaaaa aagagttgtt tgcaaatcgt
    19201 ctctttgctt ggtggattaa aatgtgtggt gcttttccta ttgatcgtga caaaccgagt
    19261 ccagatgcta ttcgttaccc tgttaatatg ctcaaaaaga gcaatcgttc tcttcttatg
    19321 tttccaagtg gaagtaggca ttcgcaagag gtcaaaggag gggtcgctgt gattgctaaa
    19381 ttggctaagg tcaagattat gccagcagcc tatcaggggc ctatgtcggt caagggatta
    19441 ctagcgggag aacgggttga catgactttt gggaatccca ttgacgtctc agatattaaa
    19501 cgcatgaatg atgaagggat tgctgaggtg gcaaaccgta ttcaggcaga gtttgatcgg
    19561 attgatgacg agttggcacc tttccaacca ggcaaagcaa ggaacccttt aacttatctc
    19621 taccgtttac cattaggatt ggttttggtg gtggtattat tattaaccat gttattttcc
    19681 tatattgcta gttttgtttg gaatccagat aaacatcgcc attaagaaca tgagggctaa
    19741 catgtgcctg aaataagaag tgattgagat tagtcttcta ttgaaagaag ccgctaatgc
    19801 ttaatcactt ttttcatttc taaaaaagat attcgatgat acccttaact cttttaagca
    19861 caaaaaatga caatactact atacttttgg atatcattta cgaataaaaa gatgaggtaa
    19921 aaaaatgtta gacgaattat taattaaagg aaaatcgttt ttgagagagc ggtattttct
    19981 gccataccta attagtcttt tattaggact ttttctaata ctaagcttca gttttttgtt
    20041 ctggggaaat aggcagagca aggcagccgt tcctgctttg agagaaatat cgcctgtgaa
    20101 acagcaggtt agtgaagaaa aaaaggaaat tcaagaagat agcagtattt tagtggattt
    20161 aaaaggcgcc gtacaaaaag agggagttta taagctaact gctagcagtc gtgtgcgaga
    20221 tgtcattgaa ctagctggag gcctaacttc agaagctgat aaacatgcta ttaattttgc
    20281 agaaaaacta actgatgagc aagttgttta tgtacctaaa caaggagaag agatttctgt
    20341 gctaccaaga tcattagttt ctggtaaaaa agaaactgcc agcaaggatc agtcaaaggt
    20401 tcatattaat aaggccagct tagaagaact acaacatatc ccaggtattg gtgctaaaag
    20461 agctcaggat attattgata tgagagataa gttaggtggt tttaaagcgt tagaagatct
    20521 ccgtcaggtt tcggggattg gcgaaaaaac gctcgagaaa ttaaaagatg acattttctt
    20581 ggactaagct agtgcccctg tcaaagattc aatttgcttt tttaatcttg gttttctttt
    20641 atcaaatcca tagccctagc tggttaacgt ttctccttag ccttagtttg atttgcttac
    20701 ttgtcaagcg tttgtctaaa aaagaatttc tcggtgtctt tgccatcctt agtttctgtg
    20761 ctttgttttt gctgtatcag aaacagcagt tggttcaaaa actggaaatt cagccaatac
    20821 aaataacctc tgtagcatta gttcctgata gtattcggat taatggtgat caattagctg
    20881 ttcttggacg tcacgggaaa cattcttatc agttatttta ccgtttgaaa agccaagcag
    20941 aagcccaatt gttcaagaaa gagcaccgtt ggttagtgat gcacgcaaaa gtgacattgg
    21001 aaaaagctga ggaagttcga aattttaaag gctttaatta tcagactttt ttgacttatc
    21061 aaggaattta caggataggg aaggtagagc aaatagaaca gcttgaagtg atttcacccg
    21121 agtcaatatg tgactatttg tcctctttaa gacgacgagc cattgttcat tgccagcagc
    21181 attttccaag acctatgtct cactacctga cgggcctcct ttttggttat ttagataagt
    21241 cgtttggtga gatgacagat tattatagtc agttgggtat cattcatctc tttgctttat
    21301 cagggatgca ggttggcttc tttctcactt gttttagaag ggtgttgcta ttactcgcag
    21361 ttcctttgga atggataaaa tggatagagc ttccttttgc ttgcttttat gccgcgttga
    21421 caggttatag tatttctgtt attcgaagcc tcgtgcagtc gcagttgcgt catttaggaa
    21481 taaaaggatt agacaatctg gcttgtactt ttttacttgt ctttttatgg gatgctcatt
    21541 tcttaatgac tgttggtggc gtattaacgt ttagctatgc ttttttgtta acagtggtta
    21601 ctgttgaaga attatcagga gctaaaagac agttggtaca agtcttgacc atttccctag
    21661 gaatattacc atttttgctc ttttattttt ccagttttaa cccaatgtca atggtcttaa
    21721 cagggctctt gtcttatctc tttgaccttt ttattttgcc ccttctttgt ctggtttttt
    21781 gtctatcccc tttggtgact gtctcaatat gtaaccatct ttttatttta ttagaaaaag
    21841 tcattcaatt tctcggaaat actttcaata gttcccttgt ttttggaagc ccgaccagtt
    21901 ggcacttgct tatcttggtg attagcttcg ctatttttta tgattatcgg caggtgcgac
    21961 aacgagttat cacttgcggt ttggttatag cgttgacact tttgtctgtc aaatatcctt
    22021 tgaccaatga agtgaccttt atcgacattg gccagggaga tagtattttg gtgagggagt
    22081 ggacagggaa aaatctctta atagatgtag gtgggcgccc tttcttttct tcaaaagagc
    22141 actggcgacg aggacatcac gtagctaatg ctcagaaaac cttaattcct tacttaaaaa
    22201 gtagaggtat tcacacaatt gaccaactat tagtaactca cgcagatact gatcatatgg
    22261 gggatatcga agtggttgcc aaagctattc ggataaagga gattttgact agtcaaggca
    22321 gtttaagcca tccaagcttt gttaggcggc taaggcgttt aaaatgtcac gttagggttt
    22381 tagcagctgg agaccagttg cctattatgg gaagtgtctt acaggtactc tacccttggc
    22441 agttagggga cgggaaaaat aacgattctt tggtacttta tggcaggctc ttaaatcgaa
    22501 cttttctttt cacaggtgac ttggaaaaag agggggaaaa cgagatcata aaacgttatc
    22561 ctcaactaag agtagattat ttaaaagcag gtcaccatgg atcaaatacc tcttctagtg
    22621 cagctttttt agaccatatt cagcctaaag tggcctttat ttctgctgga aaaaataacc
    22681 gttatcagca tcctcacaga gaaaccttag cccgtttgga agacagacaa atcacttatt
    22741 accgaacgga tacgcaagga gctattcgtt tgactggtcg gacaagctgg catcttgaaa
    22801 cggttcgtta gttaaaattc cagcctgacg aagaaacaag cagtcgcttt ccttttagga
    22861 gaaagatgat ataataaaag catgattgcg atagaaaaga ttgaaaaact gagtaaagaa
    22921 aatttgggtc ttataaccct tgtcacagga gatgacattg gtcagtatag ccagttgaaa
    22981 tcccgcttaa tggagcagat tgcttttgat aaggatgatt tggcctattc ttactttgat
    23041 atgtctgagg ccgcttatca ggatgcagaa atggatctag tgagcctacc cttctttgct
    23101 gagcagaagg tggttatttt tgaccatttg ttagatatca cgaccaataa aaaaagtttc
    23161 ttaaaagaaa aagacctaaa ggcctttgaa gcctatttag aaaatccctt agagactact
    23221 cgactaatta tctttgctcc aggtaaattg gatagtaaga gacggcttgt taagcttttg
    23281 aaacgtgatg cccttgtttt agaagccaac cctctgaaag aagcagagct aagaacttat
    23341 tttcaaaaat acagtcatca actgggttta ggtttcgaga gtggtgcctt tgaccaatta
    23401 cttttgaaat caaacgatga ttttagtcaa atcatgaaaa acatggcctt tttaaaagcc
    23461 tataaaaaaa cgggaaatat tagcctaact gatattgagc aagccattcc taaaagttta
    23521 caagataata ttttcgatct gactagactt gtcctaggag gtaaaattga tgcggctaga
    23581 gatttgattc atgatttacg gttatctgga gaagatgaca ttaaattaat cgctatcatg
    23641 ctaggccaat ttcgcttatt tttgcagctg actattcttg ctagagatgt aaaaaacgag
    23701 caacaactag tgattagttt atcagatatt cttgggcggc gggttaatcc ttaccaggtc
    23761 aagtatgcgt taaaggattc taggacctta tctcttgcct ttctaacagg agcggtgaaa
    23821 accttgattg agacagatta ccagataaaa acaggacttt atgagaagag ttatctagtt
    23881 gatattgctc tcttaaaaat catgactcac tctcaaaaat aggcgttgga ccgctttcca
    23941 agagataatc aaattagttg aaagctctta ttttttgcga taagatagac gtatcataaa
    24001 ggaaaagagg acaggaaaat ggctattatt ttaccagaac ttccatacgc gtatgatgct
    24061 cttgaaccac agtttgatgc ggagacaatg actcttcatc atgataaaca ccatgccact
    24121 tatgtcgcta ataccaatgc ggctttagaa aaacacccag agatcggaga aaatctggag
    24181 gaactattgg cagatgtcac taagattcca gaagatattc gtcaaacctt aattaataat
    24241 ggtggcggac acctaaacca tgcgcttttc tgggaactat tatcacctga aaaacaagac
    24301 gtcactcctg atgttgcaca agccattgat gatgcttttg ggtcatttga cgcctttaaa
    24361 gaacaattta cagcagctgc tactggacgt tttggttcag gttgggcatg gttagttgtt
    24421 aataaagaag gacaactcga aatcacatca accgctaacc aagatactcc aatttcagaa
    24481 ggcaaaaaac caattctagc gcttgatgtg tgggagcatg cttactactt gaattatcgt
    24541 aatgtacgtc caaattatat caaagctttc tttgaaatcg ttaattggaa aaaagtatca
    24601 gaactttacc aagccgctaa ataagaaaag ggtttccaat ctcaaaaaga gattggtttt
    24661 ttaagtgctt ttgtgaataa cagtgtgggg acatcatttt ttagaaaaga taaaaatagt
    24721 ttgtcttttt aatgtaattc cttgattttt agctaaattt agctagaata gaatggatag
    24781 gagattttag gtgttaagaa agaagaaaac taccattgta gggattattt taggaatgat
    24841 gatagtgacc ttacttgtcg gctgtttgac tggtaaaaag aaaggctttc ctcctaaagc
    24901 aggtgagcgg cagcaaacgg ctgacttaaa aatgagaaaa agattagaaa aactgttcaa
    24961 aaaccgttac ctgaaaaatc taaagaggct aagcaagctg ttatggatgc agatttagcg
    25021 caaatggatg tcttagggct ctattacgat gacaaccatt tgagtttggt caatacggtc
    25081 aaggcgtatt taaaggaatt tggcattggt gaatcccaaa ttgccttttc ctacaaagac
    25141 ctcaattcag gcaggactgc tgccatgaat gaccatcagc caatgattgc aggaagcacc
    25201 tataagctgc cattaaacat gctggtggta gataaggcaa attatccatg acagagcgtt
    25261 ttgacattac agaaactgat tatgaatatg atcaggaaca tcatgcctat gttgctcagt
    25321 tcaatggtgc catgtctatt ccggatatgc aagaatattc cttggtgtac tcagaaaaca
    25381 cgccagctta tgctctagca gaacgattgg gtggcatgaa taaggcttac caattatttg
    25441 accgctacgg gaaggtatcc ggggctatta cgaccattga tcgtaatggc aataaaatca
    25501 ccaccgctta ctatttgcaa gttttggatt acttgtggca gcatcaggat aaatataagg
    25561 atatcttgta ctacattggt gaatctttcc ctgatttgta ttacaagact tatttgcctc
    25621 atgtaaaggt ttatcaaaaa ccgggttatg tcagagaagc cttaaatgta ggtgccattg
    25681 tttgcgaaga gtctccttat ttgattgctc tttattcatc tggtttgggt ggagcaacac
    25741 aagcatcaga ggaagtcaat ggccttggtt atgtgcagct tgttcagcta ccatatgtaa
    25801 ttaatgagtg gtatagaggc aatctcaaca tgatctaata ctcagttgac attagtctga
    25861 tagtagacat acttactgat gacagtcact aaaataagtt gttgctcatt aaaaaagctt
    25921 ggcctgtttc ttcaggtcaa gctttttgag attaatgctg tgtttttgag gtcttattgt
    25981 cacctcttgt ttcttgataa tggtgaagca attttttgaa ttttttaacg gcagcgcgtg
    26041 ttagctgctt agatgatttg ccatttctgc tgtaaatggg attgtgctta tccctttgct
    26101 gttctaaatc gggaactaga aaagttgcat caggactatt aattgctttt tcaataaaag
    26161 ccggatcaaa aagcagaata gggtcaatat caagcagacg gtgcaagtca tcgttttggt
    26221 tgccataatt gaaagaagaa ccattgacaa tactatttcg cgttaggtta tcaggatcta
    26281 gtgctactaa aaattgtcca gattctgaca aaataaactc tgagtgaaaa tgaattaaaa
    26341 tcttatagtt ggcttgagga atattgtctg tatagactgc ttgatgattg ccattagcat
    26401 ctaaaatact agcaacctta ttatggtatc tagaagattc ataaagagca taatcgtcat
    26461 cttctagagt agccaaatat ttggctaagg catccgcatc ggttttccct ttattcccat
    26521 aatgtgagcg aacccactcc gtttgctggg ttgatatgag gtaacggagt tgatgaattt
    26581 tccgattaaa acggctataa ggaatgtgtt cgagattaac ataataagcc tgaatcaggg
    26641 tagataattg gtcccaaaaa ggatctgttg gcgatagctt tggacttaat tgtgccaata
    26701 cttgctgtgt ttgttttgat tgtcctgtca actcgtctgg catctttaaa tacgtcaaga
    26761 gcagttgtaa ccgtttttga gcttcttgag gcgtctgtgc catctcctct tgttgccaga
    26821 gcttttgaaa gtcaggtgat cctatcaggc gaatgcgact ataaagttgt tcgaaatgat
    26881 aagagtttcc tctaacagcg agttgttcaa ggtatccttt ttggatggct ttataggacc
    26941 atccgtcctt atcgagcttt cgaacataat caagcaagtc gtggcgtaat ttaatagctt
    27001 ctgaaagctg gagttctcgt aatttaggat agttttggta aaaaggtgcc actaaatctt
    27061 gataaagttt gtgttctttt tcaaaggcaa tccgctgata gtctttctgc caaaaactga
    27121 cgcaaaaagt cagaaacatc aagaagaata gccattttcc aagtaatttc ataggttttt
    27181 agttgacaaa catggcatcg ccaaagctaa agaaacgata cttttcgtca accgcgtgtc
    27241 tgtaagcttc aaggacaaag tcacgccctg caaaggctga tactagcatc acaagggttg
    27301 attttggaag atggaaatta gttgaaaaag catcaactac cttgaattgg tagcctggtt
    27361 taataaaaat attggtccaa cctgaatcag cttgaatgtc cccttggaac ttacctccga
    27421 tggtttccaa cgtacgaata gaggtggttc ctacagcgac aacacgaccg ccagcttgtt
    27481 tgacgtctct tagggtttgc gctgcttctt ctgagaggga ataaaattcc gaatgcatat
    27541 catgctcatc gaggttatcc acggaaacag gtctaaaagt cccaagccct acatgtaggg
    27601 tcaaataaac caaatgtacc cctttggctt cgattttttt gagcaagtct gttgtgaagt
    27661 ggagaccagc agttggggcg gccgcagagc cattttcttt agcataaacg gtttggtatc
    27721 gctcagcatc ctctaatttt tcgtgaatat aaggaggcaa tggcatttcg ccgaggctct
    27781 ctaaaacttc taagaaaatc ccatcatagc tgaattcaac aattcgtcca ccatgttcta
    27841 attcgtcgat aatggtggct ttgagacgcc catctccaaa attgacttgg ctaccaacct
    27901 tgagccgttt ggctggcttg gctaaaactt cccattgatc tccttgtgta tttttaagca
    27961 aaagcaattc cacatgacca tgagtatcgg gtttttctcc ataaagtctg gcaggcaaga
    28021 cacgggtgtt attcatgacg agggcatccc ctggatttaa ttgatcaatg atatggtcaa
    28081 aatggctatc aaccatagtt ttttgacggt gatcaataat caatagtttt gaactgtctc
    28141 ttttttcgag tggggtttgg gcaatcaatt cttctggtaa ctcaaaatca aaattgttag
    28201 tattcattgg gactccttta aagccactag taaatctctt cctagtaact ctttcatgta
    28261 agataaatct tttctattat atcacttgtc gtctaacccg tcatctttaa tctttcatca
    28321 gaaagtaaag gataggcttg acaaaaattg gtatatacca tataataaaa acacgaaagg
    28381 tctataccaa ttagaaaagg agaatgacat gaaaattatt cgggtccaag atcagattga
    28441 aggtgggaaa atcgctttta ccttattgaa agatagctta gctaagggag ctaagacgtt
    28501 aggattagca acaggaagtt caccaattag tttttaccaa gaaatggtca aaagtccttt
    28561 ggatttttcg gacttaacaa gtattaactt ggatgaatat gtcggtcttt cagtagagag
    28621 cgatcagagt tatgattatt ttatgcgtca aaaccttttt aatgcgaagc cttttaaaaa
    28681 gaattacttg cccaatggtt tagcaaccga tgtcgaagca gaagctaaac gatataacca
    28741 aatcattgca gagcatccga ttgattttca agtgcttggg attgggcgta atgggcacat
    28801 tggttttaac gaacctggga cctcttttga agaagaaacg catgtggtgg atcttcaaga
    28861 atcaaccatt gaagccaata gtcgtttctt tacaagtatt gaggatgtgc caaaacaagc
    28921 tatctctatg ggaattgcct ccatcatgaa gtccgaaatg attgttcttc ttgcctttgg
    28981 acaagaaaaa gctgatgcga tcaagggaat ggtttttgga ccaatcacag aacacctccc
    29041 agcaagtatt ctccaaaaac atgatcatgt tatcgtcatt gtggatgaag ctgctgcgtc
    29101 acaattagac taacctaacc agtcgttaaa ccttgtaaga acaaaaatga ggagatagtc
    29161 aacttcattt aagaagaagt cttgtaactt ctatttcttt tgcaagggta aatttatgtt
    29221 acactactaa tatgcgttta gataaattat tagaaggtac aaaagttggc tctagaagtc
    29281 aagtgaagaa actgattaag gctcaagggg tttgggttga tcacatgcct gccagaaatg
    29341 gtcgacaaaa tgttgatcct ggcttgcaac tgattgaggt gactggacag cgagtgacgc
    29401 atcctaaaca ttcttacatt atcctcaaca agccatcagg ggtggtctca gctaagaaag
    29461 atactaacta tttaaccgtt attgatcagc ttgctgaaga agataaaagt ccagacttgt
    29521 atcctgttgg cagattggat agagataccg aagggttggt tttactcact gataatggtc
    29581 ccctagggtt tcggatgttg caccctagtc atcatgtttc taaaacgtat cttgtaaccg
    29641 ttaatggctt gttagcagaa gatgcctcag atttttttgc agctggtatt tgtttcccaa
    29701 caggtgaaca atgccaacca gctcaattga ctattcttaa agccgataca gaccagtcac
    29761 aggctagttt gaccatttca gaaggaaaat ttcaccaagt gaaaaaaatg tttttgacct
    29821 atggtttgaa agtgacctct ctgaaacgga cgcactttgc aggactggaa ctcggtcatt
    29881 tagccagcgg agaatatcgt tatctaacag cgtcagaaag gcaactcatt aaaacgtatc
    29941 tggactgagc aaaacatgct ttcaaaaaga agctattctt gcttaatcaa taaagtgtcc
    30001 attgactatt atagtcatga tgagtccgac ttttgctatg tttagtcatc ttgttgttac
    30061 aaaatcaggt aagcaaaaag attcaattcc cactgtctcc ttaacctgaa gcgttataaa
    30121 aacccttgtg ttaaactctc ataaattgga aatgggagtg ttttttgatg gctaaaaaaa
    30181 ctaaagctac ttaaagtttg gtacttagtt ttcgaataat aaggtggaag atctaatagg
    30241 aggtgacaaa aatattaacc gctttagatg ataagaatca gctcatttcg ctagtaactc
    30301 agcctatttc aacgaaaccg ccttttcgtt gcccagcttg caaatctcct gttcgcttgc
    30361 gtcaggggac aattagacga cctcattttg cccatgtaca actagctcat tgtcaattcc
    30421 aagcagaaaa tgaatctgag gaacatttga cgttgaaggc aaaactttac accagtttag
    30481 tccgaacaga agctgtctgt attgaaaaat atcttcctga gctgcaacag atagcagacc
    30541 tttgggtgaa tgataagtta gccttagaaa ttcagtgcag tcccttgcca gttgagcgtc
    30601 taaagaaacg caccaaagcc tatcaagaaa aggggtatcc ggtacgatgg ttactgggaa
    30661 gaaaattgtg gcttaacact cacttaactg ctttgcaaaa acagtttctt tacttttcat
    30721 ctagtttggg ctttcatttg tgggagctgg atgcagctgc aaatctgcta cgtctcaaat
    30781 atttaatcca tgaagactta tttggtaagg taagttacct aaccaaaacc atttctttag
    30841 accacaatat tatggaaatg tttcggttac cctatcagca agaaatcctt tattcttatc
    30901 agaaaaaaat gactgtgaac ctatctaaaa gaatacaaag agctctttta gctagacacc
    30961 cgaaatggct acgacgacaa gaaaaggctt acttatcagg ctataattta cttatgttaa
    31021 caactgatgc tttttatcct caatggagac cagttcaatc ttccagcggt ttttgtcaaa
    31081 ttaaaggaaa tcttcgccct tattatgaaa gttttaaagt ctattataaa aaagaaaagg
    31141 ataagaaggt gcaaacgctt ttttcaccaa aatattatgt taaaatggat agtaatagaa
    31201 aatgagaagg agatgttatg actgataatc gcagccattt agaagaaaaa tacacttggg
    31261 atttgagcac tatttttgca acagataagg attgggaagc tgaagtcagt gacttagcta
    31321 ctgaagttga ggcatctaaa ggttttgctg gtcatttgct ggattctagt gctaatttgt
    31381 taaaggttac aaaaacatat ttagaattgg ctcgtcgtgt ggagaaagtc tatgtttatg
    31441 ctcacatgaa aaatgaccaa gacactactg ttgccaagta tcaagaatac caagctaagg
    31501 cttcaggctt gtatgcaaag tttagcgaag tcttttcatt ctatgatcca gaagtgatga
    31561 tgcttcatca agaagactat caggcttttc ttactgaaac ccctgagttg aaagtgtaca
    31621 accatttctt tgacaaatta ttccaagccc gcgaacatgt tcttagtcaa gcagaagagg
    31681 aattattagc aggagctcaa gaaattttca atggtgcgga agaaaccttt agtattcttg
    31741 ataacgctga cattgtcttt ccagtagtta aaaatgataa gggggaagat gttgaattaa
    31801 cccatggtaa cttcattagc ctaatggaat ctaaggaccg tagcgttcgc caagctgctt
    31861 atgaagccat gtatagtact tatgaacagt tccaacatac ttacgctaaa accttgcaaa
    31921 ccaatgtgaa agtgcaaaac tataaggcgc gtgttcataa atacgattca gcacgtcaag
    31981 ctgccatggc tgctaacttt attccagaag ctgtttacga cactttatta gaaacggtta
    32041 ataaacattt gccactctta caccgttatt tgaaattgcg tcaagaggtt cttggtttag
    32101 acgatttgaa gatgtatgat gtttacacac cattatctga aacagatcta gccattggtt
    32161 atgatgaggc tttggaaaag gctgagaagg ttttggctgt ttttggtaaa gattacgcag
    32221 atcgtgtgca tcgtgctttt accgaacgtt ggattgatgt tcatgtcaat aaagggaagc
    32281 gctctggggc ttattcaggt ggttcctatg ataccaatgc ctttattctg ttgaattggc
    32341 aagatacact tgataatctt tacacacttg tccacgaaac aggccacagt ttgcattcta
    32401 ctttcactcg tgaaacacag ccttatgtgt atggggatta tagtatcttc ttggcagaaa
    32461 ttgcatccac aacgaatgaa aatattatga cagaagctct cttaaatgag gttcaagatg
    32521 agaaagaacg ctttgccatt ttaaaccatt acctcgatgg tttccgtgga acagttttcc
    32581 gtcaaaccca atttgctgag tttgaacatg ccattcatca agctgatcaa aaaggagaag
    32641 tgttaacaag tgaatacctt aaccagctat acgctgattt aaatgaaaaa tattatggtt
    32701 taagtaaaaa agataatcat tttattcagt atgaatgggc acgtattcct catttctatt
    32761 acaattatta tgtttaccaa tatgcaacag gttttgcagc tgcaagctat ttagcagata
    32821 agattgtgca tggcacacaa gatgatatcg atcattactt ggcctacctc aagtcaggaa
    32881 attctgatta cccacttgaa gtgattgcta aagcaggcgt tgatatggaa aaaggtgatt
    32941 atttggaagc cgcctttaaa gtctttgacg aacgtctaac agaacttgaa gtactcgtgt
    33001 ccaaaggcat acacaaaagc taaaatcaca aaagtcaagg acaaaaagag tttaggattg
    33061 atagaaatgg agattcacag ttggtgtgaa tctccatttc tatcggtcat tttcttttta
    33121 tattttagtg gattatcagt cctgaaaagc aggcttcatt gaccttagtt tgacggtttc
    33181 ttttttgtct tttttattgt gtggtcactc acttaaataa aaccaatagt tgagtaaggc
    33241 gcttcagatt aacgctattc tattgtttta gagataacgt tcgcataaaa catattttta
    33301 ttatatttga cattttataa aagagataat agaa
//
LOCUS       DAUGQX010000020        32516 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUGQX010000020 DAUGQX010000000
VERSION     DAUGQX010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32516
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.020"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(198..611)
                     /locus_tag="VIA51_000871"
     CDS             complement(198..611)
                     /locus_tag="VIA51_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8682826.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPNYQAPPKRVSEPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            complement(694..1443)
                     /locus_tag="VIA51_000872"
     CDS             complement(694..1443)
                     /locus_tag="VIA51_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEQ8682827.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            complement(1463..3949)
                     /gene="gyrA"
                     /locus_tag="VIA51_000873"
     CDS             complement(1463..3949)
                     /gene="gyrA"
                     /locus_tag="VIA51_000873"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEQ8682828.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELISTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIAEINTDRENSISKNKDN"
     gene            4140..5123
                     /locus_tag="VIA51_000874"
     CDS             4140..5123
                     /locus_tag="VIA51_000874"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEQ8682829.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            complement(5282..6652)
                     /locus_tag="VIA51_000875"
     CDS             complement(5282..6652)
                     /locus_tag="VIA51_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEQ8682830.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(6893..8620)
                     /locus_tag="VIA51_000876"
     CDS             complement(6893..8620)
                     /locus_tag="VIA51_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682831.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVIIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGIVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLVLDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            complement(8617..10341)
                     /locus_tag="VIA51_000877"
     CDS             complement(8617..10341)
                     /locus_tag="VIA51_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682832.1"
                     /translation="MKRLRPYVKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGEQK"
     gene            complement(10351..10950)
                     /locus_tag="VIA51_000878"
     CDS             complement(10351..10950)
                     /locus_tag="VIA51_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEQ8682833.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAEHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            complement(10951..11928)
                     /locus_tag="VIA51_000879"
     CDS             complement(10951..11928)
                     /locus_tag="VIA51_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEQ8682834.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIEHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            complement(11935..13191)
                     /locus_tag="VIA51_000880"
     CDS             complement(11935..13191)
                     /locus_tag="VIA51_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEQ8682835.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDTDTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            complement(13181..13633)
                     /locus_tag="VIA51_000881"
     CDS             complement(13181..13633)
                     /locus_tag="VIA51_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8682836.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            complement(13651..14241)
                     /locus_tag="VIA51_000882"
     CDS             complement(13651..14241)
                     /locus_tag="VIA51_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEQ8682837.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            complement(14225..15064)
                     /gene="prmC"
                     /locus_tag="VIA51_000883"
     CDS             complement(14225..15064)
                     /gene="prmC"
                     /locus_tag="VIA51_000883"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEQ8682838.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISETFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRAVTDIFGKERMVVVDYG
                     VSS"
     gene            complement(15064..16143)
                     /gene="prfA"
                     /locus_tag="VIA51_000884"
     CDS             complement(15064..16143)
                     /gene="prfA"
                     /locus_tag="VIA51_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEQ8682839.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            complement(16178..16747)
                     /locus_tag="VIA51_000885"
     CDS             complement(16178..16747)
                     /locus_tag="VIA51_000885"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEQ8682840.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPDI"
     gene            16885..17070
                     /locus_tag="VIA51_000886"
     CDS             16885..17070
                     /locus_tag="VIA51_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEQ8682841.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            17123..18061
                     /locus_tag="VIA51_000887"
     CDS             17123..18061
                     /locus_tag="VIA51_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEQ8682842.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTSKGKQYHHILDRQTGYPIETDMLSLTIMAPSSFYCDIWTTRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(18125..19408)
                     /locus_tag="VIA51_000888"
     CDS             complement(18125..19408)
                     /locus_tag="VIA51_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEQ8682843.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(19408..19989)
                     /locus_tag="VIA51_000889"
     CDS             complement(19408..19989)
                     /locus_tag="VIA51_000889"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEQ8682844.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     regulatory      complement(20076..20171)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(20294..21277)
                     /gene="guaC"
                     /locus_tag="VIA51_000890"
     CDS             complement(20294..21277)
                     /gene="guaC"
                     /locus_tag="VIA51_000890"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEQ8682845.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHFESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     gene            complement(21555..23081)
                     /locus_tag="VIA51_000891"
     CDS             complement(21555..23081)
                     /locus_tag="VIA51_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEQ8682846.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            complement(23074..23802)
                     /locus_tag="VIA51_000892"
     CDS             complement(23074..23802)
                     /locus_tag="VIA51_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682847.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQTELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVVNLFGGDEHA"
     gene            24222..24911
                     /locus_tag="VIA51_000893"
     CDS             24222..24911
                     /locus_tag="VIA51_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEQ8682848.1"
                     /translation="MKNAISILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     QSNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHTFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            complement(25105..25877)
                     /locus_tag="VIA51_000894"
                     /pseudo
     CDS             complement(25105..25877)
                     /locus_tag="VIA51_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
     gene            complement(26004..26999)
                     /gene="pta"
                     /locus_tag="VIA51_000895"
     CDS             complement(26004..26999)
                     /gene="pta"
                     /locus_tag="VIA51_000895"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEQ8682849.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVEVRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIATGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            complement(27003..27908)
                     /locus_tag="VIA51_000896"
     CDS             complement(27003..27908)
                     /locus_tag="VIA51_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8682850.1"
                     /translation="MRFEFVADKRIKVKTLLKSYDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGMLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSCAIHLTDDFDSVIIGLQKKDRGY"
     gene            complement(27905..28741)
                     /locus_tag="VIA51_000897"
     CDS             complement(27905..28741)
                     /locus_tag="VIA51_000897"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEQ8682851.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            complement(28716..29387)
                     /locus_tag="VIA51_000898"
     CDS             complement(28716..29387)
                     /locus_tag="VIA51_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8682852.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            29475..30053
                     /locus_tag="VIA51_000899"
     CDS             29475..30053
                     /locus_tag="VIA51_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEQ8682853.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFVNSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHITFKYAKSKVARCINTLKKFNDK"
     gene            30193..31173
                     /locus_tag="VIA51_000900"
     CDS             30193..31173
                     /locus_tag="VIA51_000900"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8682854.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSNG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAADVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            31170..32297
                     /locus_tag="VIA51_000901"
     CDS             31170..32297
                     /locus_tag="VIA51_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8682855.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            32287..>32516
                     /locus_tag="VIA51_000902"
     CDS             32287..>32516
                     /locus_tag="VIA51_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8682856.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAITDQS"
BASE COUNT        10045 a         6730 c         5646 g        10095 t
ORIGIN      
        1 tatcgtcaaa tattttgctt ttcctatagt tattctatta aaaaacttcg acaagattac
       61 tccaaaaatt gctcttcact ttgaaagtta accaaatcat ttaacgatca aaagagatta
      121 atcaagcaaa tgaagataca acaaataact atttttaacg agttttatag cacgatccag
      181 tcgttaacct aataagtcta ttcatgtaat tctaaaggca aaccatccgg atcaaaaaag
      241 aaagtcattt tctcacctgt gtaatcatca tgcctgatag gctccactgg aattcctaag
      301 ctctttagat catctacata actctcaatg ttggtaacac gaaatgcaag gtgcctcaaa
      361 ccacaggcct cacttttaaa ttctggttca cttacacgtt taggaggagc ttgatagttg
      421 gggtcacttg tcaccttacc aaaaatctcc aattcaatac gaccacaaga taaatctaat
      481 ttgtaatcat gcttgtcagg acgataattt tctctgataa tttcaaatcc gagtttattc
      541 acataaaaat cttttgacag atgataatca gatacaataa tagcaacgtg atgaatggca
      601 tttagtttca tcatatttct cctttcaaaa aaagtaggat gagataaatt ttctctatgg
      661 tcctactttt taaatattat atttaagata tatctaggta gatacttggt tataagaatg
      721 attaaaagct ttcaatacat cggcgggcgc tttatcaaaa tcgtattctg tttttagttc
      781 tcctttgaca ataatacgtt ctgttgcttc gatatctgta caagtcacta aagtcacttc
      841 tttgagacca gctgtatcat cgataacatc aacgcgttca ggagctaccg tgaaaacatc
      901 ttttatgatg tattcgtaaa ttttttcttt atctgttaaa tagatggaca tcccattttg
      961 tgctctttca agcggcgaaa agagcatttg agatgaacct gtaattccaa aaatatgatg
     1021 actggcaaga gaataattat tttctcctcc cataacttgt tcttctttca tcgttcctgc
     1081 gccataaata agctcagtat ttcctaaacc tttaaaaatt ggtaaattaa tgccaagctc
     1141 tggtatggca atgcccccta taacaggaag ttgctgagcc gccatttgtg cttgcaagac
     1201 actctctgta ctaactggct ctacggcttg gaaatcaaat gttgacttag cctctttatt
     1261 ctttttgatt tgttttttcg aaactttcgt tacttgatat ttattagagt ttcgagcaat
     1321 taatgtattt cggataggtt tgttaaaaag caatgctaaa cctagaatta aaagtacagc
     1381 tattagtagt tttcttgccc aagacatgga ttttattttt cgacgctttt gtttttttac
     1441 cattttttac tccttattat gattaattat ctttattttt tgaaatacta ttttcacgat
     1501 cagtattgat ttcagcgata ctactgtctt caggctgaac caaggtaaat gttacaatct
     1561 tagcatcagc atctagtttc ataattttaa cacccaaagt agcacgacct gtttgcgaaa
     1621 tatttgcaac atttgtgcga ataatgacac ctttatttgt aatcaccatg atatcttctg
     1681 taccatctac ggtaaccaat ccagccaatt gaccattttt aggggtaata ttagctgttt
     1741 ttattccttt tcccccccta ccttttgtag gatagtctgt agcacttgtt ctcttaccaa
     1801 agccattttc ggtaattaca agaacttctt ggttatcttg aatacgtgac gcgccaacaa
     1861 cgcgatcatc ttcacgaagc ttaaccccgc gaacacccgt agctgatcgg cccatgttgc
     1921 ggatgcttgc ttcattaaaa cgaacagaat atccggaatg agttccaatg ataatgtcat
     1981 cctgaccgct tgtcaaaagg acgttaatca gctgatctcc ctctttcaac ttaagagcac
     2041 ggagaccgtt ttgacggata ttattaaatt ctgaaacttc tgtacgtttg acaatgcctt
     2101 gtttcgttgt aaagaagaag gatttacctg ctgtttcttc cttacgtgcg ttgataatag
     2161 tttgaatggt ttcaccatct tctaatttca atagattaac aattggaaga ccttttgctg
     2221 tacgaccata ttctggaatt tcgtaagctt tcaaccgata gacacgccca aaattcgtaa
     2281 agaagagcaa agtatcatgg gtacttgttg atatcaattc acgtacaaag tcgtcattgt
     2341 tgactccagt tccttggacg ccacgtccac cacgcttctg ggcacgaaat tcatcttgag
     2401 caagacgctt gatataacct ttatttgaca aggtaatcaa aacatcttct tcttcaatta
     2461 gatcttcatc ttctagagaa aggacttcac cgaccattaa ttctgtacgg cgtgggttag
     2521 cgtatttacg cttgatctca tccatttctt ctttgatgat agtgataata cgttctggtt
     2581 tggctaaaat atcagataag tcagcaatca aggccaacaa atcatcatat tctgattgaa
     2641 tcttatcacg ttccaaacca gtcaaacgac gcaaacgcat atccaaaata gcttggcttt
     2701 ggcgttcaga caagtcgaaa cgtgacatca attctgtctg agcaatgaca tctgtctcgc
     2761 tgttacgaat aatagcaatc acttcgtcta aatgatcaag ggcaatcagt aagccttcta
     2821 aaatatgagc tctggcttca gctttatctt tatcaaatcg ggtgcgacgt ataataactt
     2881 ctttttgatg actaatgtaa ttatcaatga tttgtctgag tgacaatatt ttaggcacac
     2941 cattttcaat agccaacata ttaaaactga aattcgtctg aagacttgtt aatttaaaga
     3001 ggttatttaa gataactgtc gcggatgcct ctcgacgaat ctcgataaca aaacgcactc
     3061 cttcacggct agattcgtca cgaactgctg taataccttc tagtcttttt tcttgtgcta
     3121 aacgaacaat gtgttcatgc actttcgttt tattgacgcc atagggaaat tcagtaacca
     3181 caatacgttc ccgacctgtt tgagttgttt caatttctgt tcgagagcgt aaaacgatag
     3241 aacctttacc agtatcataa gccctatgaa tacctgagcg ccccataaca agggcaccag
     3301 tcggaaagtc aggtccaggg atcacttcca tcaactctct tgttgtacag tctggatgtt
     3361 ccattaccat cttgacagca tcaatagact ctgccaaatt atgaggcgga atgttagttg
     3421 ccatcccaac ggcaatccct gtcgctccat tgactaataa attaggaaag cgagctggta
     3481 atactactgg ttctctttcg cttccatcgt agttatcttg aaaattaacg gtatttttat
     3541 tgatatccct taataattca agcgcaattt tactcatgcg cgcttcagta taacgttgag
     3601 cggcagcacc atcaccatcc atagaaccaa aattgccatg cccatcaaca agcatatggc
     3661 gataactcca ccactgagcc atacgaacca tagcttcata aatagaagaa tccccatgcg
     3721 ggtgatattt acccatgaca tcacccgtaa tacgagcaga ttttttatgc ggtttatcag
     3781 gtgtcacacc gagttcattc atcccataga gaatacgacg atgcacaggt ttcagaccat
     3841 cacgcacatc tggcaaagct cttgccacaa tgacactcat ggcatagtca atgaaactcg
     3901 ttttcatttc acttgtcaga ttgacgtcaa ttaaatttcg atcttgcatt taaggaatgc
     3961 tccttttcta gtcaatacta gatttcatta taccataaat tccttatttt ttcttattgg
     4021 aagcgttatc agtaaactat tttcattatt tttctgaatt caatgacaaa caattatcaa
     4081 tatgttaaaa taagaccgta tgagcttttg ctctaataaa attaaggaga tgtttagaaa
     4141 tgactgcaac taaacaacac aaaaaagtaa tcttggtcgg tgatggtgcc gtcggttcat
     4201 catacgcttt tgcattggta acacaaaata ttgctcaaga acttggtatt attgatattt
     4261 ttaaagaaaa aactcaagga gatgcagaag atttaagcca cgctctagct tttacatcac
     4321 ctaaaaaaat ctatgcagct gactactcag actgtcatga tgctgatctt gttgtcttaa
     4381 cagctggtgc tcctcaaaaa ccaggtgaaa cacgccttga ccttgttgaa aaaaaccttc
     4441 gtatcaataa agaggttgtt acacaaatcg ttgcatctgg tttcaaagga atctttcttg
     4501 ttgctgctaa cccagttgac gttttgactt actcaacatg gaaattctca ggtttcccta
     4561 aagagcgtgt cattggttca ggtacatctc tagattcagc ccgtttccgt caagctctgg
     4621 ctgctaaaat cggtgttgat gcgcgttcgg ttcacgctta catcatggga gaacacggtg
     4681 actctgaatt tgctgtttgg tcacacgcta acgttgctgg tgtaggtctt tacgactggc
     4741 tccaagctaa tcgtgacatt gatgagcaag gcctagttga tcttttcatt tctgtacgtg
     4801 atgctgctta ctcaatcatc aataaaaaag gtgctacttt ctacggtatt gcagttgccc
     4861 tagctcgtat tacaaaagct attcttgatg atgaaaatgc tgttcttccg ctttctgttt
     4921 tccaagaagg ccaatacgaa ggtgttgaag attgctatat tggtcaacca gctatcgttg
     4981 gagcgtatgg aattgttcgt ccagtaaaca ttccacttaa cgatgctgaa ttacaaaaaa
     5041 tgcaagcctc tgcaaatcaa ttgaaagcta tcattgatga agcctttgct aaggaagaat
     5101 ttgcttctgc tgctaaaaac taatcacaaa agagacttcg gtctcttttt gttttgcctg
     5161 atattccttt tccaacgtgc tataagagga taatcataag tttagaactt ttcaggttgc
     5221 aacaattaaa aagcaaaaaa gccagtgctg ctgaactgct ctggcttttt cctatcagat
     5281 actagtcttt ggcaccaagt gctgccattg tgatgtagtt gtaaggtttg ttgaaatgtg
     5341 gtaagaagaa aatatcagtt aatgccaact tttcaatggt tacgccttct tggatagcaa
     5401 gtgagaacat gtgaattccc attgacacat cttcacgggc tgccatttga gcacccaaga
     5461 tacgacgtga gtctttatcg taaacaatct taatggttac tgggaagtta ccgtgttcga
     5521 taaattcagg tttttggtta tcagtatact cagtcactgc agcatcaaaa ccaagacgtt
     5581 ttgctttttc aagtgtcaaa ccagttgaaa ccatgtgcaa tccgtaaatg gaaataccgt
     5641 ttgagccttg aacgccaata ccttcaaggt ctgtaccaca agcgttatgt gctgctacaa
     5701 ttcctgtacg gacggcattt gaagctaaag caatgtagtt tgtatcgcga gtagcattat
     5761 cgtagatagt tgcacagtca ccgatagcat aaacacctgg aatagaagtt tcttggcgtt
     5821 tattgacaag gaaagcacca ttacggaaaa gatcaatctt accatttcca agagttgtgt
     5881 ttggacggaa accaacggcg aggataacca tatccacatc gtactcattt ttgtcagtaa
     5941 tgatcttttc aaccttacca ttaccagcta cttctttaac tgtttcacca aaggctagtt
     6001 gaataccatg ttcttccatg tttttagcca ttaagtcagt caaatcacgg tcgtaataac
     6061 ctgccaagca agtgtccacg acatcaatca gaaccacttc tttgcctttg cgttggaaag
     6121 cttcagctaa ctcaacacca atgtaaccag caccaactac ggctacacgt ttaatgtctt
     6181 tgttttcaag ctttgcaatc acatcagctg agttttggta taacttcaca aattgaagat
     6241 tttcaagagt tgcttcaaat tcaagtgatc cttctttgat ttcggcacct ttaatcggtg
     6301 gtaagatagg ttgtgagcca gttgcaaaaa tcaacttgtc gtaagtttcc acgtggtttt
     6361 taccatcaac aagcgctgtc actgttttgg catcgtagtc gattgattga acaggtgatt
     6421 ccatgtaaac tttagcccct aaagactcta attcttcttt atctgaatag aaaagtcctt
     6481 ctggtccagc aatttgctca ccaatccaaa gtgccatacc acagcctaaa aatgaaatat
     6541 ttgagttttg gtcaaataca acaatctcat tagcatcacc gtagtttgtt aacatagtct
     6601 tgatacaggc cgtaccagca tggtttgcac caacaacaac gattttactc atatattttg
     6661 ttcctcattt cacaatatta tatagggctc tattatacca cagtcaaaaa acgcttccaa
     6721 atatattgct cacttttttg agttatttct tctttagtca actgtttttt ctcacttata
     6781 aaaaaagatc gtccgctttt tcgctgttat ttttttatat aacagcttaa agtttgttaa
     6841 ttaactaact ttaggaaggc ttaaaaagtt aacctttgtt aaaagacgaa ctttattcta
     6901 tcttttgtaa tctagcataa cagccgtttt ttgacattaa gctggcatgt gttccccact
     6961 caaccaatcg accttgatcc ataacaagaa tcaaatcagc tgattgaatc gttgataaac
     7021 gatgggcaat gataaagctg gtccttcctc tcatgagttc ttttagtgcc tcttgaataa
     7081 cagcttctgt tctaatatca atagaggagg tggcttcatc tagaaccaag acttttggtt
     7141 ttttcaaaaa cattctggca atagctaata actggagctg cccttgggac aaagcatcat
     7201 cagaagcact taagtaagta tcataagtct taggaagttg cataataaag aagtgtgcat
     7261 gagctgcttt ggctgctgcc actacttcat cacggctagc ctcttcactg ccgtaagcaa
     7321 tcaactcatg aacagtcgca tctttcaacc aggtttcttg caatactatg ccagtaatgg
     7381 acctaagttc ttccttagca taacacttaa taggaacttt atctaacttg atgctaccag
     7441 catcaagttc ataaaagcgc atgagtaaat tgattaaagt tgatttacct gcacctgtag
     7501 gccctacaat cgctaccttg gaacccgcag gaacagaaaa attaatatct ttcagtaagg
     7561 gcctgtcttt ttgataagaa aaacttactt cttcaaagtc aatttgcccc ttaaccgctg
     7621 atgccttaaa tgttagaaag tgctcttgct cttttatttc aatatctaaa aggtcataaa
     7681 gcctttgcgc acaagctaaa gaactctgta tctctgccaa gacagatgaa atatcgttga
     7741 aaggtttggt atattggaca acaacattta aaaaagtggt tagctgacct actgaaaaaa
     7801 gtccagccat gatacgaaca gcccctaaac ctgccagtaa agcataaatg acactattaa
     7861 taaagcgagt ggctggattg actgttgagg cgtaaaaaat ggctttttgt gaagcctcgc
     7921 aataggtttt atttaaaaca tgataatcac agatagactg ctcttgagca ttaaacagtt
     7981 gaaccaaacc ttcttgacga aggatttctt cagtaaactg agctaaattt cctctgcttt
     8041 tggtctgtgc ttgtgcataa tgaaaactct tttgagcaat aaaacgagct aaaaagaggg
     8101 agcttggtgt taacaccaaa accaagatta acatgagcca gtcaatctgt gccatagcta
     8161 taatggtaca cagaatcgtc aatagtccaa gtataaactg gttaaaaacc atttgtagac
     8221 cattgatcag ttgctcagtg tcggttatca ctcgactaac caaatctcca atggtttgac
     8281 gatctagata tgcaaaagga agacgatgaa ttttttccaa aagcttatct ttcaattgct
     8341 ggctatattg atatagcaaa cgactataga caagaggcat cacccattga atcaatgtgt
     8401 tgaccacaat aataactaac atttgcccca acagccattt taaagtttgc caagaattga
     8461 ctgacaaact catatcaacg gctttaccga taagaacagg caagtaaaca cttaaaccaa
     8521 cttgtacaaa actagcgatc acgagaatac aaacaggtag aggttttttt aacaaatcct
     8581 gaagcactcg ctttaggagg tgatgatctg ttttaatcat ttttgctccc ccttcacgta
     8641 aagcgctagc atttcttgat aaagtgcatt gcttactttt aactggtcat gactggcaaa
     8701 atccaattga tggccctgtt ccaacactaa aatcttatca gcaaactgca aattcttaat
     8761 agattgcgtg actagaatca ctaaaacatc tgataactct tcttttagag ctttaaaaag
     8821 tcgtcctcga gtctcattgt ctaaggcgga actggcatca tccaaaatca aaatgggttt
     8881 tggcttcaga agtgctctgg caatagctag acgttgccgt tgccctcctg aaaaatgacg
     8941 gccgaaggct tcaacaggtg cctctaattg ttctggtaag gcagcgacaa actcttttgc
     9001 ttgagccaat tcaagagccc gccacagttc ctcatcacta ataggcattg attgtcccag
     9061 taggaggtta cttctaatcg ttcctttaaa taattgagct ttttgaggaa caagagcaat
     9121 cacatttcgc cactcggtta gtgtttttgg cacttctcct tgccaattaa gactaatctc
     9181 accactatat tgtgaataag tttggcagat caagtcaatc aaagtcgttt tgcctgctcc
     9241 agtaccacca atgatgccaa tccattctcc ctgatcagca cttaactgaa tatcatacag
     9301 acttggctct gctgctcctg gataagtaaa ggtcaagtgc cggatggtca acagatgagt
     9361 tgaaatagga ccatctttaa gtaagggcaa aggcgcttca tcagctaaaa caaacacctg
     9421 attaatccgt tttgcggctg ttacactttg attgatggtt cccatcaaca tggtcatttt
     9481 caaaagttct gccaaaatct gcaagaggta attaattaaa gcaaccaaca tgccctgact
     9541 aagcgatcta tgagctactt gccaacttcc ttgccaaatc aagattaaca gggtaagatt
     9601 gaccactaaa aaagtcatag gattcaagac attggctagg gtagcagctt gatattggtg
     9661 gcgacttaag agcatatttt gctgcttaaa tgcttggagt tctttttggg tttgattaaa
     9721 agccttaatt actcggattc cttgtaactg ttggctagtc aaacgaacca agtgatctgt
     9781 ttctcggcgg attaagagat aaaggggacc taataaatgt gacataacaa aaacaagtgt
     9841 tagtaagaca atcaccatca tcacaaacca tagggttaga cttggactaa tccaataagc
     9901 cattaccata gcaccacata cgataatagg ggcccttaga aaaagacgca aaaattgatt
     9961 gataccagtt tgaatttgaa aactatcact ggtcaatcgt gataacagac tagcataacc
    10021 aagatggtct tggtcctcct tgctcaaaaa catgattttt ttaaacaagt catctgtcat
    10081 ttgtcttgta aaaccaacag ctgctttcga agaaaaatac tgggctgtaa cggaaagcaa
    10141 taagccaatg gttgctaaac caaataatgt taaaacaacc ctcaaaattc cctggctgtt
    10201 gtgttgacta atcgatatat caatcatgtt agcaattaac aaagggacta ataattcaaa
    10261 taaagcttct aataatttaa aaagaggacc taagatactt tcttttaggt accctttcac
    10321 atatggacgt aatcgtttca tgataacttt ctaaaaaagg ctcatcagtt caattaaata
    10381 aagattgaaa tgaacttctc gtgagtaata gatattgccg ccattcttat aaagcttacc
    10441 tccagaaatc aaggcgaggg ggtggtaata aaaataggtt tgaccactag tgttgcctag
    10501 gcttggcgcc acaacggttt tggaataggt agtcgctaaa tcaacggtat tttgacctcc
    10561 atgttcagca atataatcaa tataagctgt tccaaaatta taggcctgaa cagccgtcca
    10621 agaatctact cctgcttcct cagctagagc aagattatga gacagtaaat tcaccccgtg
    10681 ctcaatactg gcctgactat ctgtaatcga gtttttttgt cctgaactgc tttcactgga
    10741 ttgcatgaca tctgcttctc ctccttttgt ctcggtgtat atcatagcta agactaagtc
    10801 tacatttgcc tttgtatcat tttctgctaa tgttttctca accataggct tatatgccaa
    10861 aacacgttga acattgtgat gaataacaaa ggattgataa atgacaaaaa gaagaagaaa
    10921 actgcaggca cgctttaaaa gtctaaacat ctatttggtt ttaatatcct ctatattttt
    10981 aatcaagatt gaataagtcc catcatcatt taacaaaaat tcaaccgctt cagcatcctg
    11041 ataaatggca tttggtactg ttaattctat cccgtttgat aacgatagct tttgattttc
    11101 tagttttttt atctgtctag aatgttcaat atcgctaatt tttataggtt ctggaatgac
    11161 atctttgact tgatccacaa aggttaaacg ggctgttaaa ttatcatcaa agagttggtc
    11221 agctaatttt tctggtgata aaacgtcgtc tgcttctaac tgcttaaaaa gagtggattt
    11281 catctttgac tgaaaagtaa aatcatcttg attaaaatgc tctgcaattt tttgagcggt
    11341 ttgttctatc attttgatag actttttaac agattgctca ggtgtaactt tcaagaggtg
    11401 ttctgaaaaa taattagcaa aactgccatt atgcttcaca cgcttttcaa tcaagtagta
    11461 ctgaccagat ttgagattaa tgactagtgc ttcatctggt gtctgggtgg gactcggcag
    11521 attattctgc gtcaccgtaa atggatgttc ataattgtca gaaaggtgag caaactgttc
    11581 tttcaaagca attcgcaaga aagcaaaaaa gggttcgcca tccttatcaa actgaacaaa
    11641 gactaagtca ttggtttttt gatcctctga aataacaaag gcttccttcc ataactgggc
    11701 aatggtaaca gacgtttcca acaaatcatc accaatggtt gtaaaaaagg tattattagc
    11761 ctcaaactga ccacgtttgg cttcgtccga gaacactttg gccaattttt ttcggaaata
    11821 ttcatcaatt cgcggtgtaa tgctcactaa acgatctgat aacagtaact cagtgtcatt
    11881 gggagaaaat tgatgaatga caatacgttt tatataacta tctaacatga ttccttactt
    11941 tttatagagt gggaaggcat cggttaactg acgcacttcc tgacggactt cttcaagaat
    12001 agtttcttga tcatgattaa ccaaggcttt gatgataaga cgggcaatgg tctgactctc
    12061 tttaacaccc ataccacggc tggttatggc agcacaacca atgcgaatac ctgaggtttt
    12121 aaatggcgac aaggtttcaa aaggaatggc atttttatta agggtaatat taacctcatc
    12181 cagaagattt tgcgctagtt taccattagc aataacctta gtgacatcta ctaaaaagac
    12241 atgattatct gtaccacctg agatcagacg gaaacgatca tcttgtgcaa aaactgctgc
    12301 catagccgca gtattatcaa taatagcttg tgcatagtct ttaaaggctg gatccaaggc
    12361 ttctttgaag gcaaccgctt tggcagcaat cacgtgttcc agaggtcctc cttgtaaacc
    12421 agggaaaacg gccgaattaa tctttttagc aagagcttcg tcattggtta atatcaagcc
    12481 tccacgagga ccacgtaagg ttttatgggt tgttgatgtc acaatatgcg cataagggac
    12541 aggactcggg tgcacacctg ctgctacaag gccagcgatg tgagccatgt ccaccattaa
    12601 gtaagcacct acgtgatcag caatggcacg aaacttttca aaatcaatgc ttctagagta
    12661 ggccgaagcc cctgcaacga taagctttgg ttggaccgcc tttgcttgtt ctaaaatcgc
    12721 ctcataattt aacatttcag tatcagtatc tactgagtaa cccacaaaat ggtaggtttt
    12781 tccagaaaaa tttactggag agccatgcgt gagatgacca cctgcagcca aatccattcc
    12841 taatacggtg tcaccagcct caatcaaggc catataagct gctgcattgg cttgacttcc
    12901 ggaatgggct tgaacattgg caaatgcggc accgaaaagt ttcttagcac gttcaatagc
    12961 aagcgtttcg acaatatcca cacattctgt tccaccataa tagcgattac ctggatagcc
    13021 ttctgcatac ttattggtta aaacagaacc ttgagctgcc atgacagctt ttgaaaccat
    13081 gttttcagat gcaatcaatt cgatatgatg ttcttgtctt tcttcttcag catgaatggc
    13141 atcccaaagc tctttatcaa agtcttcaac attaccttta tcaaaaatca ttgtcatctc
    13201 cttgtaagtt tttgatgaat cgtaattgtg ttttatcatc tgcatagtcg aggtttcggt
    13261 aaaaagcatg cgcttcttta cgatgactgg cagaattgag gcgaataaag gcaatgcctt
    13321 cctgcctagc ttgggattcc agggccctta gtaaggcact cccaattccc cttctctgat
    13381 aggctggtaa aacagccaag cccaagagat taagaccatc agaagcataa agggtttcat
    13441 accgttcagc gtgaacatag cctaataatt gattggtatc cttgtcggca taagctaaaa
    13501 aatagtgatg gcaatcctca atcaatcgtt catattgcct ttctaacaag tcaagcgaaa
    13561 ctaaatagcc aagggctttg gcattaattt cttgtagcat aggacagtcc gttttactta
    13621 atggtctcaa cattccaagc ggctcctctc ttaaaagcga agttcaggca cgttagctaa
    13681 taattcttct ttggtgatag caccttgacg taaaatcaca gcacgctcac ctgataagtc
    13741 taagatggtt gaatccttac ctgttagaaa aggatcatct gcataaccaa acacttgaaa
    13801 gtcaaaatct tgcataatat gatcaaaaac tcgaccacta gctttgccag ataagtttgc
    13861 agaaggacca attaaagggc ctgttttttg aattaaagct gcggtaattg gatgactggg
    13921 taagcgaaaa ccaaccgttg aaagtcccga attaatccaa taaggaacct ggtcattagc
    13981 ttttaaaata atcgttaacg gacctggtaa aaaggcttgg tataatttct tgaggtatct
    14041 cggctgttct tttgaaaagg ctaagatact attaaaatca gccacattaa ggttcattgc
    14101 tttatctcgg ggtctttgtt ttaagtcata aacagcattt actgcttttt catctaaagc
    14161 cttggcaaaa agaccataaa ccgtttctgt tggtaaaaca agggcatcac ctgattcaat
    14221 gatactagct agatactcca taatcaacaa ccaccatcct ttctttgcca aatatatccg
    14281 ttacggctcg tatatgtctt tgaggaaaat aggcttgtaa catatctttt ataccttcag
    14341 cttgcttata accaatttca aagtaaagct tcccctcctt agttaagtaa ttgtcagctt
    14401 gttcaataat cttacggtaa atagcatagc cattttcttt agcaaaaagt gccaaatgag
    14461 gctctgattg caaaacattt agactgactt cttccttatc ctcgtaggat atgtagggag
    14521 gatttgacac aataatatca aatgtttctg aaatgagact aaaaacatct gattcaataa
    14581 acgttatatc aagctggtaa gcatcagcat tggcttttgc caagtcaaga gcagctctag
    14641 aaatatcaga tgccgttact tgccagttag gcctttcttt tttgagagaa atagcaatcg
    14701 ctccactacc tgtaccaata tctaaaacat tcaacggtgc atcaagattt tcagctaaaa
    14761 tcatgtcaac taattcttct gtttctggcc ttggaattaa tacacgcttg tcgactgcaa
    14821 gcttcaaatc acgaaaataa gcattacctg taatatattg aggagataaa tgctgactta
    14881 gagaacagaa aatatgttcc aaaagaacag catcttcagg agtcacagct tgattttggt
    14941 gaatcaacat atctagactt gaccattctt tgatttctct aaaaacatag gcgagatttt
    15001 cgcgatcctc atctatttgt tctagtttat cttcataagt tctgattaat gtagcatagt
    15061 tcattagtta ttgagagatt ctaatttctt tgtctgatca tacataacga gtgcatcaat
    15121 aacttcatcc atttttccag ataaaatagt atctaatttt tgaagtgtca aaccaatacg
    15181 atgatctgtt acacgatttt gcgggaaatt ataagtacga atacgttctg aacgatcacc
    15241 agtaccaact gttgatttac gttcagcatc ttgttcatct tgagcaattt gcgcaaaatg
    15301 gtcagcaaca cgagcacgaa tgattttcat cgctttatca cggttttttt gctgagtacg
    15361 ctcttcttgc atttcaactt tgattcctgt aggaatgtgt accatacgaa ctgcagtagc
    15421 aactttattg acattctgac caccagcacc agacgcgtgg taaatatcga cgcgaaggtc
    15481 tttaggatca atgtcgtatt ctacttcttc aacttctggc attaccaaaa cagttgcagt
    15541 tgaagtatga acacgaccct gactctctgt cactgggaca cgttgaacac gatgagctcc
    15601 tgattcatat ttaagcttag aataaactga ctgaccagaa accatggcaa ccacttcttt
    15661 aataccacca acaccattaa cggatgattc cataacttca aaacgccatc cttgagtttc
    15721 agcatatttt tgatacattg ttaaaagatc accagcaaaa agcgctgctt catcgccacc
    15781 agcagcacca cgaatttcta aaataatgtt tttatcatcg ttaggatctt taggtaatag
    15841 aaggattttt aatttttctt catactcttc tttagctgct tttgattctt taagttcttc
    15901 tttagccatt tcttctaatt caggatcacc actggcatct ttgatcattt cttcagcatc
    15961 tgaaatggtt tgaatgactt gcttatattc tctataagct gtgacagttt ctcgagtatt
    16021 agcttcttca cgtgataatt ccataaatcg ctttgtatct gagacaacat ctggatcact
    16081 aagtaactca cctaactctt cataacgatc ttcaactgcc tgcaattgat cataaatatt
    16141 catttttctt tgtatctcct ttaaaaccga ttacctttta aatatctgga ttaaaataat
    16201 gttttcgaca aactgggata tatgtttcat taccaccaat ttgtatctga tcaccttcat
    16261 agacaggttt tccgttttct gtccttaaaa ccatggttgc tttcttacta cagtattggc
    16321 aaattgtttt gatttcatca atcttatcgg ccaataatag caaatgtttt gaaccttcaa
    16381 aaagattgtt ttggaaatca tttttcaaac caaaagccat gacaggaaca tttagctcat
    16441 ccaccacacg cgccaaatca taaacatttt gcttgcttaa aaattggctt tcgtcaatca
    16501 ggacacaata aggtttttcc tccaattggg caataaatgt gaaaatatcc atgtcatttg
    16561 aaatggggat agcttctcgt cgcataccaa tacggcttga gacgatgcca aaaccatcac
    16621 gtgtatcaag agcacttgtc ataatgacaa caggtttgcc ttgttcttca tagttatgag
    16681 caacttttaa aatttcaatg gttttaccag aattcattgt cccatattta taatagagtt
    16741 gagccaaagc ggaaaatcct actttctata gtattctacc tattttacca caaaggctga
    16801 agttttccca gccattgaaa acagtgtata ctttttcaca gcattatgtt acaatgatgc
    16861 ccaataacat aaaggagtaa cattatgcca tttgtaacaa ttgacttgtt tgagggacgc
    16921 tcacaagaac aaaaaaatca attagctcgc gaggttaccg aagtagtctc acgcattgca
    16981 aaagcaccta aagaaaatat ccatgttttt atcaacgata tgcctgaagg aacttactat
    17041 cctcaaggtg aaatgaaaca aaaatcataa tgaccttccc ccactcctta gtgggggtat
    17101 tctgctaaaa agaggactaa ttatgtttgt tacgcaacaa ttaaagctaa tgggaacagt
    17161 tattgatatt cagatcgaat ctgacaaagc ttgccaacaa ctaagtagag tcattgactt
    17221 attatatact tacaaaaatc gtttttcagc taatgattca aactctgaat tgatggctat
    17281 taatcaggcg gctggtgtta aacccgtcag cgttcactct gatttattta acctaatcca
    17341 aattggtaaa gctcatagct tgtcaacacc aagtaatctt aatatcgcca ttgggccact
    17401 tgttcaagcc tggcgaattg gatttgaaga tgctagagtg cctagtcata accttatctc
    17461 acaacagtta gctctaacag atcctagaca ggttcttata gatgacaaaa aacagactgt
    17521 ctttttacaa caagtaggaa tggctttaga cttaggagcc ttagcaaaag gttatattac
    17581 tgataagatt atggcctacc tgattgaaga tggtattgac tctgccctta ttaatttagg
    17641 tggaaatgta cgcgttcatg gacctaatcc gaaaagccct gacaagactt ttcgaattgg
    17701 cattcaaaaa ccagatgcta aacgtgggca acatcttggt gtcatcaagg ttaacaatca
    17761 ctctgttgtg acttctggaa tttatgaaag gcagtttaca tccaaaggga aacagtatca
    17821 tcatatctta gatcgtcaga caggctaccc tatagaaaca gatatgctta gcttaacgat
    17881 catggctcct tcttcttttt attgtgacat atggactacc cgtttatttg gtcttgatag
    17941 ctcaatgatt atcacacttt taaatacctt tgataatatt gaaggtcttc tagtaacaag
    18001 aaagcaccat gtccttatgt caaatggttt gagacactat tttcaaccat actatcatta
    18061 aaaggggtta acggtttgct caaaactgat cacagaaaaa acggctcaat tagccgtttt
    18121 ttaattattc atcttgtttg tctttgccat ttaaaactaa atttaagaca acagaggtca
    18181 aagtggcaat cacaatacca ttcgttaaga acatttgagc tgtctctggt aagctggcaa
    18241 aaagattagt gccattaaag cctaaacctg ctgagatgga aacggcagca ataataaaat
    18301 tatactcgtt cttttggaaa tcaacacgat taagcatttg cattccttga agagcaacca
    18361 taccaaagag aacaagcatg gctccaccaa gaactgggct tggaatcatt tgtgccattg
    18421 ctccaaattt agggagtagg ccaatgacca caaggatacc tgctgcgtag taaatcggac
    18481 gacgggtttt aatacctgag atttggacaa gtccaacgtt ttgagaaaaa ccagtgtaag
    18541 ggaaggtgtt aaataaccca ccgagaaaga ctgcgatccc ttctgagcga taaccattgc
    18601 gcaaacgttt ttcatctaat tgatcattag tcaaatctga aagcgctaag tagacacctg
    18661 ttgattcaac catagaaacc gttgcgatga tacacatcat cacaatagaa gtgatttcaa
    18721 aagttggcat gccaaaataa aatggggttg gcacatgaat ccaagaagcc tctacaacag
    18781 gagttgtatc tactaatccc atcatagctg aaaccaaagt tcccgctaca agcccaatca
    18841 aaatggaaat ggatttcaca aaacctttgg taaatttttg gactaaaaga ataatgacaa
    18901 tcgtcaacaa tgataacatc atgctttgtg ccgtaggctc tttgacgtta tctcccatat
    18961 tccccatagc aacacctacg agacttaagc caataacggt aatgaccgat cctgtaacaa
    19021 ttggtgggaa gaaacgagca atcttagaaa aaatacctgc cactaaaatg acataaattc
    19081 ctgacgcaat gagggctcca aacatggcac ctgaaccttg ttgcgctcca ataatggata
    19141 gaggtgccac tgattgaaaa gcacatccta aaacaactgg taatcccact cccgtatgct
    19201 tggttaactt taactgtaag aaagtagcca caccacacat gaaaatatct gtcgaaatca
    19261 ggtaggtcaa ctctctagcg gaataaccta aagcacctgc gatcataatt ggtactaaaa
    19321 tagatccggc atacatcgaa agcacatgct gtaagccaag gacagctgat tgcgagtgag
    19381 aatgttcctg ctttgttgaa tgtgtcatta tgcgtcagcc tccaagaagt ttagattacc
    19441 attttcaaag tttttaatac gggctaatga ggtcacttca atgcccatat cttcaatcaa
    19501 tcgacgacca tcttggaaag atttctcaat cacaatacca acgccgacga cttgtgcccc
    19561 tgcttgacca ataatctcaa tcaagccttt ggctgcctga ccattagcta aaaagtcatc
    19621 aataatcaaa accttgtctt ctttagatag gaatttacca gcgatagaca ccgtgctcgt
    19681 cacttgttta gtgaaagaat aaacttctgc tgtcaaaatg ccttctgtca tggtaatgtt
    19741 tttatgtttt ttcgcaaaaa tcataggaac atccattgct tctgcagcgt atacggctgg
    19801 tgcaatacct gaagcttcga ttgtaaccac ttttgtaatg ccagcctcag catatttttg
    19861 agcaaacact ttaccaattg ctttcatcaa ccggtaatca acttgatgag ttaaaaaatt
    19921 atctaccttt agaatattct ctcctagaat attgccatct gttaagatgc gttcttcaag
    19981 taactgcata aatctccttt tgattcaaat agaaaaagcc tgccgcaaag ccagaaacta
    20041 taagagtttc tcactttgca aggttaaaaa ccaagcaagc ctaaaagctt acttattgtt
    20101 agacattaag gtgtcttgta gagacgctgc gccaattcac agcataaata agtatgtcat
    20161 tattgaattc attataataa tttactattt taccatgttt cttatttttt tcaataccta
    20221 cagagatatg ataaaagcat ctccagcatt aagctaaaaa attctttact ggtcctagct
    20281 aactccatat catttaaatg gaatcaccat tccaaataga atttttgacg ataacataat
    20341 caacatgacg caaactgtct aaatctttac cacccgcgta agaaatggac gattgcaaat
    20401 cctgttgcat ttcggtcagg gtatctgata agtgaccttt tgtaggcaat aagatttttt
    20461 tgccttctac atttttatgc tcgccttttt gatattctga cgccgagcca taatattctt
    20521 taaacgtttc accatccact tctaccgttt ttccaggact ttcaaaatgt cctgcaaaaa
    20581 gcgatccaat catgaccata ctagctccaa agcggatgga tttagcaata tcaccatgtg
    20641 tgcgaatccc accatcagca atgataggtt tacgagctgc ctttgcgcac cagcgcagtg
    20701 ctgctagctg ccaaccacct gtaccgaaac cggttttaac tttagtgata catactttgc
    20761 ctggaccgat gcctacttta gtagcatcag cacctgcatt ttcgagttct cgtacagctt
    20821 ctggcgtacc aacatttcca gcaatgacaa atgtttctgg taattcagtc ttgatatgct
    20881 taatcatatc aataacactg ttagcatgac catgagcaat atcaatggtg ataaactcag
    20941 gagcatcctc tttcaaagag gtcacaaatt catattcaca agctttaacc ccaacagaga
    21001 ttgatgcaat caagccttgt tcatgcatgc gtttgataaa aggtttgcgg ctatcttcat
    21061 caaaacgatg cataatataa aaataaccct cttttgccaa ctgctcagca attgtttcat
    21121 caataatggt ttgcatattt gctgggataa ctggtagctt gaactggtat tttccgagtg
    21181 tcacacttgt atctgcttgt gaacgactag taataatgca cttgttagga atcagttgaa
    21241 tatcttcata atcaaataca gggatgtcat taaacataag tttctcctct tttaacatag
    21301 attaagaaaa acaagttagt tctcaccttc ttctctaagt cctctataca aaataatctt
    21361 cctatgacct ctgatgatta gaggtatctt taggtaaaaa cttacctttc attttataga
    21421 ttacttattt gtttatgttt tgtcaaattt atatgctatt tttaatttta aagttcggtt
    21481 tttgtgttta tgaattgtta cttcttgaac ttaagagacg aaaaaatgcc agtcctacgg
    21541 accaacattt ctgtttattt ctggattaag cctgttttca acagataatc tcgagcgacc
    21601 ttattagcat ctgctccttt aacagatacc tcgtagttca tgtcctgcat ctctttttca
    21661 gtaatttttc ccgctaattg attaagaatg ccttttaatt ctggatgttt tgttaataag
    21721 gaagttttca tcaaaggagc tccctgataa ggtggaaaca actgtttatc atcctttaaa
    21781 actttcaaat ggtatttcgt aatttcagca tccgtagagt aagcatctgt tacttggata
    21841 tctcctgatt gaattgcttg ataacgaaga gctggctcca tcgtcgccac agatagctgt
    21901 aatccatatt gagattgcat tcccttatag ccatctgctc tgtccttaaa ttccaaagta
    21961 aaaccggcct ttaaagtatc agcatgcgct tttaaatcag aaatggtttc aatctgatat
    22021 tccttagcca atttttctgg catagcaaca gcatacgtat tttggtaagc aaatggcttg
    22081 agaagggtca gtttatcttg cttagcaatg ccttttttag catcctcata gacctgctta
    22141 gggtcattag acaaaggtgg tttgtcgcgt aaaagacttg atgttatggt tcctgtaaat
    22201 tcaggataca tatcaatatc tccagattta agggcttcat ataagaagct agttttccca
    22261 aaattagatt tcaactcaac acttatatct gattggtctt caattaattc cttatagaga
    22321 ttaatcagaa tatcgggctc tgctcccaat ttaccggcaa taaccactgt atcttttcct
    22381 tttgaaaact gactaagcgc cataggagta tacgatgcta gcagtgcaag taaggtaatt
    22441 ccaaaactaa tcataatccg tcgcaaggaa gctttctcaa ggtactgtaa caaactattg
    22501 aaaataatag ctagcagagc tgaagaaata gcccctatca gaatcaggtt agcattatta
    22561 cgatcaatcc ctaataagat gaaagagcca agtccaccgg ctcctatcaa ggaagctaaa
    22621 gtagctgtgc cgataatcat gactgctgac gtccgcacac ctgacataat aacaggcatg
    22681 gcaattggaa tctcaaatgt tttcaatcgc tcccatttgg tcatcccaaa agctattcct
    22741 gcttccacga gacttgggtc aataccattt aatcctgtga tggtgttttg taaaatcgga
    22801 aaaatcgcat agataactaa agctgtcact gcaggcaacg ttccaattcc cattaaaggg
    22861 atgaaaagac caagcaaagc cagtgaggga atggtttgaa aaacacctgt tacctgtaac
    22921 ataatgtctg accaacgttt gctgcgactg agaagggctg ctaaaggcac acctattagc
    22981 aaggcgatca taagagataa aagggaaatt tgcaggtgtt cccccagagc cgccagccat
    23041 tcattaaaac ggttttggaa agttacaaac aaactaggca tgctcatcac ctccaaataa
    23101 attgaccaca aaagcattag cagggtgggt cttaatcatt tctgggcgat ccagttgcac
    23161 aatttctccc tcatttaaaa tagctacgcg gtctcctaat ttaatggcct catcaatatc
    23221 atgtgtcaca aatacaatcg tcatgtcaaa ttccttgtga agactcaaca ttaactcttg
    23281 caattgttta cgtgaaatag gatctaaggc tgaaaatggt tcatccatca atagaatttt
    23341 aggatgagaa atgatagcac gtacaatacc aatacgttgc tgttcacctc ccgataaatc
    23401 acttgggtaa cgatcaagat aatctttagc aggtaggccc accttatcca ataattcttc
    23461 agttttttgt ctaatttctt cagctgacca ttgcttcatc tcagggataa tcgcaatatt
    23521 ttcagctact gtgagattgg ggaacagagc aatttgctgc aatacgtatc caatagatag
    23581 cctcatctca cgtaaatcta actctgtctg tgggacgtta tttagtaaaa tatctccaga
    23641 gcttggttca ataaggcaat taatcatttt taaaagtgtg gtcttgcccg atccgctggg
    23701 gccaaccagc acaaaaaatt cacgatcatt aatttgaaag gtctgctctt gcaaaacctt
    23761 tgtctgacca aaagttttag aaacattatt aaaacgtatc attatttctc caattcattg
    23821 gttaaagtaa cagcataaaa gctgatgagt tcattcaacc tgtctctctg tcattttttc
    23881 tcaaaacgtt ctgagtaact acaaggaatc actgcatgcc ctaccatttt tagacaaacg
    23941 catctactaa ttaaagggac tcttaggtat cctcagtaag gtagaaacta ccaattctca
    24001 aaaacttttt ctctcattat tttcttgtcg tttgttgttg accattataa aaagtttccc
    24061 actataagtc aaataatgag actattaccc ccttatagaa aaacaggtca ctgggtcagc
    24121 ctatctctcc aaaattacct tatcaaaaat cctagacttg cctatgatga tagataagca
    24181 gattaattgt cttttctaga aaatacagct atcatacaat tatgaaaaat gctatttcca
    24241 ttttagcgct cttaacacct gaaaaccaac ttgaagagac gtttattaga gagctttccc
    24301 accacttctc acaccttttt gaggtgacta ttctcactag caaagccaac attcagtcaa
    24361 atcaattgtc gactttccaa ggaattttca gtttccatga gcatgacatt gacttgccta
    24421 cactctattt caaaacttct caacatggtc agggcttttt agtgacagaa agtgtctttg
    24481 atcaagcaac agcagtctta tcgttaagcc aatacctcac tggattttac caaaaatttg
    24541 atggacattt tttacagtac cttcctttgc aagcaaggtt atctgatgca aatggaaaca
    24601 tcatagtcga taatcatact tttaatggaa gttttttgcc aactactgat aaagaaatag
    24661 aagattggat tcttgctgaa ttgcgtttat cagataaccc ttgtaaaacc ttcctacttc
    24721 cttcgggttc attggatcat atttacatgc agcattatca agctcttaaa aatcctcaag
    24781 gtcagctggt gggagttttg gataccgttc aagacattaa accgttatta aaccagtatt
    24841 tagaagaaac tggacaagcc attgttggct ggtccgatgt cacatcaggc ccttccattt
    24901 tagatcacta aacttgattt taaataggga gttcagccta aatcatcaac gcacaagaag
    24961 caatcatgaa cgcttgaaga cctcaaaacc ttcttcttga ctgctttttt tgatgactga
    25021 atcggtaagt ctcacttata aagaataagc catcccagta aaccattttt ctaaagatta
    25081 ttattcttat ggactcatcc cttgctagtc acgagtaact ggttgcggtc cataactttg
    25141 cgacactggc atcagctcaa tacgattaac attaacatga gggggctgat gaatcaccca
    25201 tgatacggtc gacgcaatat tttgaggttg aatggcatgt gctccttgat aaatggcctt
    25261 cacccgttcc tcatcaccat taaagcggac ctttgaaaat tctgtccctt tgaaaattct
    25321 gtcccttcac atagaccggg ttcaatattg gtcacacgta tatggctacc tgctaaatca
    25381 gctcgtaaat tgagtgagaa ctgcttaaca aaagccttgc tagccccata aatattagct
    25441 cccggatagg gaattgtccc tgcggttgac cctaaattaa taataatacc atcatctttg
    25501 gagaccatat gtggtaataa ttgacgtgtg agataaatca acccaacaat attggtatta
    25561 atcatcgtca tccaattctc aaaatcggct tcataagcct tatcaagtcc taatgccaag
    25621 cctgcattat tcactaaaat agtaatatct tgccactgat ttggtagact tgtcaaagca
    25681 tcatcaatcg ctttggtatc tgtgacatcc atctgcaaag ggtaaaagtt gtccgaccca
    25741 aagctcgttt ctaaggcctt gagtttctca agacgacgag aagcaccaat aacctttatc
    25801 ccatctgcaa ttaagtgttc gacaatggct ctgccaaaac cggctgaagc ccctgttact
    25861 aaggcaatat ttcccataca tttcctcacc ttcaaaaaaa acgagatggt ctggccaact
    25921 cgtttttaat aatgtcaatt agtcttagga caaattctaa cacatcactt agcagttaga
    25981 atcctatatc aaggggtctt gagttaccct tggctttcaa tagcttgtgc tgctgtaata
    26041 atggctagtt tgtaaatatc ttcagcgctt gagccacgag ataaatcatt aacaggtttg
    26101 ttcaatcctt gtaagattgg tccaatagca tcaaacattc ctaaacgttg tgcaattttg
    26161 taaccaatat ttccagactg caagtcaggg aaaacgaaag tattagcttg accagcaacc
    26221 gctgaatctg gtgctttgat agccgctgtt tcaggaacaa aggctgcatc aaattgcaac
    26281 tcgccatcaa gtgccaaatc agggttcaac cctgtagcaa tttctgttgc ttctcttacc
    26341 ttatcaactt gaggcgcttt accagaacct tttgttgaga agcttaacat agcaatttta
    26401 ggatcaatat caaagatttt agctgtttca gctgtgttaa cagcgatttc tgccaattct
    26461 tgtgctgttg ggtcgatatt gatagcacaa tcagcaaaca cgtaacgctc gctcgtattt
    26521 tcgcggttca tcaagaagac acctgaagtt cttgagatac ctggtttagt tttgatgatt
    26581 tgaagagctg gacgaacagt gtcagctgtt gaatgaatag cccctgatac cattccatct
    26641 gctaatccca ttttaaccaa cataacacca aagtaattaa catcacgaag cattttatct
    26701 gcatcttcaa gcgttgcttt tcctttacgg acctcaacaa aagcttcttt cattttgtca
    26761 aaatccgcat attcatttgg attaatgata gtatagtctt gatcagcgaa acctaatttt
    26821 gtcaaaaggt tgcgtacctc ttctgactgt ccaaggataa tcggttctaa gagtccttca
    26881 aatttcaaac gagcagctgc acggacgacg cgctcatcat taccttctgg gaaaacaatc
    26941 ttcatgtttt taccaagaat tttttctctt aaaccaccga ataaactacg aatactcatt
    27001 ctttaataac ctctatcttt tttctgtaaa cctatgataa cgctatcaaa gtcatctgtc
    27061 aagtgtattg cacagctaca atcactttct gtaaatggat ctttgaaatt caaataatga
    27121 caatgtaaag cttgccttgt tattcctaag tccaaacgac ctccgtaaag gtcatcccct
    27181 aaaagtggaa aaccaatatg ggcaaaatga actctgattt gatgggtacg tcctgtatgc
    27241 aatttgatat ccactaaatg cacattttct gaatagcgcg ccacaacctt atagctagtc
    27301 ttggcatatt tgcccatagg gtcaactgcc ctggtaataa tactatcttt tgaacgccca
    27361 attggagcaa taatatctcc ttcatctggc aacatcccat ttccagaaac cagagcaaaa
    27421 taacgtttct ctattgagcg agtttggagt tgcttgtcca accttgcatg agcataacca
    27481 tgcttagcaa ataacatcaa gccactcgta tctctgtcta aacgagtcac gatatgcact
    27541 tgttggtcta ggtaatgatt gtccacataa tatgccttga taaagttagc aatggtattg
    27601 gagtggatgg cacttggaat actggcaaag ccaatgggtt tattaatcac caaaaaatga
    27661 tcatcctcgt gaacaatatc caaatcaaaa gggatggctt caagcttttc aaagggctct
    27721 tcgtttggaa tgtcaatggt gacaacatct cccacttgca ataaataaat ggcattttgt
    27781 tcaataccat tcactaatat attaccgccc ttatatttga ttttagccaa tagtccttta
    27841 gagacatcat aactttttaa aagggttttt acttttattc gtttgtctgc tacaaattca
    27901 aatctcatga gtcaatctct ccaataaagg catccttgac cctttcccaa aagctcgtat
    27961 gactcggaga ggaaacaaaa tgaattttct catcgtcgat aaaatactcc accttcgtca
    28021 cattttttaa ctgataggtt ttattatcaa tggaaatggt ataaattcct aatcgttttg
    28081 gcactaactc aatcttatct tttttgggaa taatgattga tgagcccaag gttctaaaga
    28141 cacggttatt aagactggaa atttccgtca attgcagcgc ttcaatcgtc ggatgcaaga
    28201 cagcaccacc taaagattta ttgtaggctg tgctccctgt cggggtcgat actgaaatcc
    28261 catcacctcg gaagctttca aatttgacat ggttaataat aacatctgct accatcgttt
    28321 tttcaatacg cttaaccgtc gcttcattca aagcacgcgc tttaaccaca cgaccatcat
    28381 ctaaagtaat agcaactttt aaaatcggat aagagatttg ttctcccttg tcttttctta
    28441 aattatcaat taatttatca acttcaaaat ccctataatc ggtataaaag ccaagatgac
    28501 cggtgtggat tcctacaaaa cgtaccttat ctaattcttt ttcatacatg tgaaaggcag
    28561 ataagagcat cccatctccg ccaatagaaa tcacaatatc cggatttttc tttgaaagat
    28621 agaaatcagg atcatcttta aatacggaga aaagtttgga ggcgacgcgt ttactttggt
    28681 acttaccatt tgcaataata gcaactcgtt ttaccttacc tgtataattc atctgtgtca
    28741 tcactatttc ctacaccatc acttaaattt cgtgtcacgg ggtcaaacaa taattgagcc
    28801 tcccgaatat cttctcgaat cttacgcatt tcttcgtcta attctaaagc aattttagca
    28861 gtcacttcaa gacgcttttt aatttcttct gggaagtctc caccatattt ataatttaaa
    28921 gaatgctcaa tggtcgccca aaagttcatt gccaaagtac gaatctgaat ctccgctaag
    28981 accttttttt gaccttcaat ggtgtcaaca gggtactcaa ccaccacatg ataagacctg
    29041 tagccactgg acttcatatt gcgaatataa tctcgttcat aaacaattgt catgtcttgt
    29101 cgttgacgca atagagctaa gacttcttcc acatcatcaa caaactgaac cataatacgt
    29161 agtccagcaa tatcttgaat atcttgtgct atattttctt caataacacc acgtaaaatc
    29221 attttttctt taatactttc aattgactta acacgtcccg taacaaattc aatcggagaa
    29281 taacgatttt gcttacgata ttgcttgcga ataccccgta gttttatttt taattcacca
    29341 actgtttgga tataaggatc taaaaattct tcccaatcta aggtcatcta ttgtctcctt
    29401 tcttgtcaaa gccaggataa taatataaaa ttgaaataac aatttattat agcacaaatt
    29461 aaaaggaatt tcccatgact aacctagaaa tcgaatataa aactctactt acaaaaaatg
    29521 agtataaccg tcttttatct caaatgaaac atgtgacgcc tgttacacaa actaattact
    29581 atattgatac aaaagcattt gatttaaaag ctaacaaaat gtcattacgt attcgaacat
    29641 ttgtaaatag cgccgaatta accctaaaag tgccagaaaa agtggggaat cgtgagtaca
    29701 atgtccctct ttttcttgaa caagcaaaag atatgattaa acatgggaat cttcctgaat
    29761 caactgctct tgatattatt atttcaaaag gtatcaaacc atctgcactg gtaacttttg
    29821 gcaatttaac taccgttcgt cgcgagacag tgataccgat aggtaaattg gccttagact
    29881 ataacctata tgccaatacc aaagactatg aattagaatt agaagtaagt gacgctcttc
    29941 aaggaaagat tgattttgat tcttttttat ctgaacatca cattactttc aaatatgcta
    30001 aaagcaaagt agctcggtgt attaatacct taaaaaagtt caacgataaa taatggctaa
    30061 aagcgacaga aaaactgaaa tttttctgtt tttctgttaa aatagggatg tcaattaaac
    30121 acttttgggt aatgtgactc attaataaaa cagtttaccc aattttattg aagttaagga
    30181 gctaaatcta tcatgactga acgatatgct gacaagcaaa tcaaactgtt ctcactcaca
    30241 tcaaatcttc caattgctga aaaaattgct aaagctgctg gaatccctct tggaaaaatg
    30301 tcttcacgtc aattttccaa tggagaaatt atgatcaata ttgaagaaac agtgcgtgga
    30361 gatgatatct atattattca atccactagt tttcctgtca atgataatct ttgggaatta
    30421 ctcatcatga ttgatgcttg taaacgtgca agtgctaata ccgtcaatat tgtattgcca
    30481 tactttggtt actctcgtca agaccgtgtc gctaagcccc gcgaaccgat tactgctaaa
    30541 ctagtagcta atatgctgac taaagctggt attgatcgtg tagtgacgct tgacttacat
    30601 gctgttcagg tacaaggttt ttttgatatt ccagtggata acctctttac agtccctctt
    30661 tttgcagaac gttacagtaa attaggctta tcaggttctg atgttgttgt cgttagccct
    30721 aaaaattctg gaattaaacg tgctagaagc ttggctgaat atcttgattc cccgattgct
    30781 attatcgact atgcacaaga tgattctgaa cgtgaacaag gttatattat tggtgatgtt
    30841 tctggtaaaa aagccatttt aattgatgat attttaaata ctgggaaaac ctttgcagaa
    30901 gctgctaaaa ttcttgaacg ctcaggcgct actgatactt acgcggtcgc tagccatggc
    30961 ttatttgctg gtggagctgc tgatgtatta gaaacagctc caatcaaaga aattatcgtt
    31021 acagattctg ttaaaactaa aaatcgtgtg ccagaaaacg ttacttatct tagcgccagt
    31081 gatttaatcg cagaagctat tattcgtatc catgaaagaa gacccttaag tccgcttttt
    31141 tcttatcaac ctaaaggcaa aaataacgca tgacttactt tgataacgcc gccaccacac
    31201 cacttagtcc taatgtgatt agggcgatga cagcagctat gcaagataac tttggtaacc
    31261 cctctagtat tcatttctac ggtcgccgag ccaataaaat ccttcgtgaa tgccgacaag
    31321 ctatcgctag aaacttgggg gcaagtgaac agcaaattat agtaacgtcc ggtggaactg
    31381 aaagcaataa tatggccata aaaggctatg ctttagctca tcaagcaaag ggcaaacatc
    31441 tcatcacaac tactattgag caccactctg tgcttcatac catggcctat ctcgaagagc
    31501 gatttggttt tgaggtcact tatttgcctt gtcaaaatgg acaaataaat ttatctgact
    31561 taaaacaagc cttgagagat gacaccattt tggtaagcat aatgtatgcc aataacgaaa
    31621 caggtgacct gttacctatt aaggacattg ggaatctgct caaagaccat caagctgctt
    31681 ttcatgttga tgccgttcaa gctgttggca aactcaagat tattcctagc gaacttggga
    31741 ttgacttttt atctgcttct gctcacaaat ttcatggtcc taaaggatgc ggctttttat
    31801 acagtaacgg acaaccaatc gaccctcttc ttcacggggg tgatcaagaa ggaaagcgac
    31861 gcgcaagtac tgaaaatatg ttaggtatta ttggtatggc acaagctttg actgatgcta
    31921 tgacttgtct tgaccaatca actgatcaca ttattagttt acgtcatcac ttgattagcc
    31981 tcctagaagg actaccctac tatattaatc aaggtactca ttatcttcct catgttctca
    32041 atattggatt tttaggctac caaaatacta ttttactaac acaacttgac ttagcaggca
    32101 ttgcagtatc aactggttct gcttgtactg ctggagctgt taatccaagt catgttttag
    32161 ctgcgtacta tggggatgac tcttctcgtt taaaagaatc aattcgtatc agtttttcag
    32221 atcaaaatag cattgaagat gttaatcaat tagctcaaac attaaaaaat attttaggag
    32281 gaacagatgg cttttgaaaa agaaattaag cttaaagact gtaaatacct ttatacaatc
    32341 agtccaaaca ttaaaaaata taccctaaga gatactacat ttagtcaaac taaagtaggg
    32401 cactaccaat taatacgttt actcgaaaaa atacctaatt caggggatgg tttcccttta
    32461 aaaatcacta ttaataaaga actcacaggg tttaaattag ctatcaccga tcagtc
//
LOCUS       DAUGQX010000021        31510 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUGQX010000021 DAUGQX010000000
VERSION     DAUGQX010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31510
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.021"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            51..4157
                     /gene="cas9"
                     /locus_tag="VIA51_000903"
     CDS             51..4157
                     /gene="cas9"
                     /locus_tag="VIA51_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEQ8682857.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSK
                     SRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKE
                     HPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLGGD"
     gene            4157..5026
                     /gene="cas1"
                     /locus_tag="VIA51_000904"
     CDS             4157..5026
                     /gene="cas1"
                     /locus_tag="VIA51_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8682858.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKA
                     LNNEGKGVPEFRI"
     gene            5023..5364
                     /gene="cas2"
                     /locus_tag="VIA51_000905"
     CDS             5023..5364
                     /gene="cas2"
                     /locus_tag="VIA51_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8682859.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5354..6016
                     /gene="csn2"
                     /locus_tag="VIA51_000906"
     CDS             5354..6016
                     /gene="csn2"
                     /locus_tag="VIA51_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEQ8682860.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYEEDSEL
                     KFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
     repeat_region   6119..6352
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6119..6154
                     /rpt_unit_seq="gttttagagctatgctgttttgaatggtcccaaaac"
     gene            6465..6872
                     /locus_tag="VIA51_000907"
                     /pseudo
     CDS             6465..6872
                     /locus_tag="VIA51_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            6996..8828
                     /gene="lepA"
                     /locus_tag="VIA51_000908"
     CDS             6996..8828
                     /gene="lepA"
                     /locus_tag="VIA51_000908"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEQ8682861.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK"
     gene            8985..9962
                     /gene="slc2/slcB"
                     /locus_tag="VIA51_000909"
     CDS             8985..9962
                     /gene="slc2/slcB"
                     /locus_tag="VIA51_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_164232585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin Scl2"
                     /protein_id="HEQ8682862.1"
                     /translation="MIKEKRGNKNCEQNKTKHSLLCRYGLTSAAALLLTFGGASAVKA
                     EENEKVREQEKLIQQLSEKLVEINDLQTLNGDKESIQSLVDYLTRRGKLEEEWMEYLN
                     SGIQRKLFVGPKGPAGEKGEQGPTGKQGERGETGPAGPRGDKGETGDKGAQGPVGPAG
                     KDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGQDGKDGLPGK
                     DGQPGKPAPKTPEVPQNPDTAPHTPKTPRIPGQSKDVTPAPQNPSNRGLNKPQTQGGN
                     QLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN"
     gene            10148..10585
                     /gene="msrB"
                     /locus_tag="VIA51_000910"
     CDS             10148..10585
                     /gene="msrB"
                     /locus_tag="VIA51_000910"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8682863.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            10700..11719
                     /locus_tag="VIA51_000911"
     CDS             10700..11719
                     /locus_tag="VIA51_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEQ8682864.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGLQKWLRLDVNTATLVGVGSSICGGSAVAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            11926..12351
                     /locus_tag="VIA51_000912"
     CDS             11926..12351
                     /locus_tag="VIA51_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8682865.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            12370..12861
                     /locus_tag="VIA51_000913"
     CDS             12370..12861
                     /locus_tag="VIA51_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8682866.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            12878..13687
                     /locus_tag="VIA51_000914"
     CDS             12878..13687
                     /locus_tag="VIA51_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8682867.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            13684..14511
                     /locus_tag="VIA51_000915"
     CDS             13684..14511
                     /locus_tag="VIA51_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8682868.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            14647..16296
                     /locus_tag="VIA51_000916"
     CDS             14647..16296
                     /locus_tag="VIA51_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8682869.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRATHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLEVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            16300..17088
                     /locus_tag="VIA51_000917"
     CDS             16300..17088
                     /locus_tag="VIA51_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8682870.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEVTKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            17082..18128
                     /locus_tag="VIA51_000918"
     CDS             17082..18128
                     /locus_tag="VIA51_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8682871.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNVAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTNADAWAYMKRLLVNMNSIRATSSSEV
                     YQSVAEGKMIVGLTYEDPCINLQKSGANVSIVYPKEGTVFVPSSVAIIKHAPNMTEAK
                     LFINFMLSRDVQNAFGQSTSNRPIRQDAQTSHDMKALETIATLKEDYAYVTKHKKKIV
                     ATYNQLRQRLEKAK"
     gene            18225..18730
                     /locus_tag="VIA51_000919"
                     /pseudo
     CDS             18225..18730
                     /locus_tag="VIA51_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            18907..19473
                     /locus_tag="VIA51_000920"
     CDS             18907..19473
                     /locus_tag="VIA51_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEQ8682872.1"
                     /translation="MTTEFDKMTRGEWYDANFDSELIQKRMMAQDLCFDLNQLKPSRE
                     EERSAVLNQLFGQSFEGLVLLSPFICDYGKNITFGKNCFINSNCYFMDGAKIALGDNV
                     FVGPSTGFYTANHPLDYKRRNEGLEKALPITIGDNVWFGANVNVMPGVTIGSGCVIAS
                     GSVVTHDIPVNSLAAGVPCQVVRKIEQE"
     gene            19489..20178
                     /locus_tag="VIA51_000921"
     CDS             19489..20178
                     /locus_tag="VIA51_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEQ8682873.1"
                     /translation="MHYNFLFFDLDHTLLDFDAAEEVALTKLLEEYQVIDIKAYKDYY
                     KPMNQNLWKQLEGGDISKADLVNSRFALLFAHFGVTVDGRQLAEGYQKHLKDQGQVYA
                     GAKELLADLTAQGYNLYAATNGIATIQQGRLQASGLAPYFKAIFISEQSGSQKPKKAF
                     YDWMTQQVSNYQPDQALMIGDSLSADVQGGINAGMDTLWYNPKHLLNNSPVHPTYEVS
                     DYQALLNCIAE"
     gene            20273..21670
                     /locus_tag="VIA51_000922"
     CDS             20273..21670
                     /locus_tag="VIA51_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEQ8682874.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVNLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNGNTKV"
     gene            21772..23568
                     /gene="uvrC"
                     /locus_tag="VIA51_000923"
     CDS             21772..23568
                     /gene="uvrC"
                     /locus_tag="VIA51_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEQ8682875.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASKEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYTDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            23753..24355
                     /locus_tag="VIA51_000924"
     CDS             23753..24355
                     /locus_tag="VIA51_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEQ8682876.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            24480..25889
                     /gene="pepV"
                     /locus_tag="VIA51_000925"
     CDS             24480..25889
                     /gene="pepV"
                     /locus_tag="VIA51_000925"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEQ8682877.1"
                     /translation="MTTIDFKAEVDKRKKAMLADLVDLLRINSERDDQLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLDVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGLTKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(25957..27333)
                     /gene="mnmE"
                     /locus_tag="VIA51_000926"
     CDS             complement(25957..27333)
                     /gene="mnmE"
                     /locus_tag="VIA51_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEQ8682878.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIINPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLESLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     misc_feature    27501..27636
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            27666..28166
                     /locus_tag="VIA51_000927"
     CDS             27666..28166
                     /locus_tag="VIA51_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEQ8682879.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVIVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            28231..28596
                     /gene="rplL"
                     /locus_tag="VIA51_000928"
     CDS             28231..28596
                     /gene="rplL"
                     /locus_tag="VIA51_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEQ8682880.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            28895..29494
                     /locus_tag="VIA51_000929"
                     /pseudo
     CDS             28895..29494
                     /locus_tag="VIA51_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            29669..29994
                     /locus_tag="VIA51_000930"
                     /pseudo
     CDS             29669..29994
                     /locus_tag="VIA51_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            29985..30259
                     /locus_tag="VIA51_000931"
                     /pseudo
     CDS             29985..30259
                     /locus_tag="VIA51_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            30308..30517
                     /locus_tag="VIA51_000932"
     CDS             30308..30517
                     /locus_tag="VIA51_000932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682881.1"
                     /translation="MTDRVVKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLLN
                     RANSLEELLLKAKEVNLTIDLKQKM"
     gene            30782..31477
                     /locus_tag="VIA51_000933"
     CDS             30782..31477
                     /locus_tag="VIA51_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
                     /protein_id="HEQ8682882.1"
                     /translation="MEHQIERLIAEDIYIKVSFSVKQSGLIFIPNYQLDIRKEENHKK
                     YKVYIRETAQFFIYNKEASELNRYMRGHELICQLTNDSKSIPKRRRQTIDTLKKKIEE
                     ISLLIELDTENKPYQDIKDDIVKDMAQLDLTITELQDHIAHLNKVAEVLLNLNNNDIE
                     NRRLARYDYAKMNLTAAIKIEEVEKEIETSQNELNISIDEYEYLVRRLEKFGEILSDS
                     KIIDTSRNEIQWE"
BASE COUNT         9996 a         5456 c         6643 g         9415 t
ORIGIN      
        1 atcaaactca ttatggattt aatttaaact ttttatttta ggaggcaaaa atggataaga
       61 aatactcaat aggcttagat atcggcacaa atagcgtcgg atgggcggtg atcactgatg
      121 attataaggt tccgtctaaa aagttcaagg ttctgggaaa tacagaccgc cacagtatca
      181 aaaaaaatct tataggggct cttttatttg acagtggaga gacagcggaa gcgactcgtc
      241 tcaaacggac agctcgtaga aggtatacac gtcggaagaa tcgtatttgt tatctacagg
      301 agattttttc aaatgagatg gcgaaagtag atgatagttt ctttcatcga cttgaagagt
      361 cttttttggt ggaagaagac aagaagcatg aacgtcatcc tatttttgga aatatagtag
      421 atgaagttgc ttatcatgag aaatatccaa ctatctatca tctgcgaaaa aaattggtag
      481 attctactga taaagcggat ttgcgcttaa tctatttggc cttagcgcat atgattaagt
      541 ttcgtggtca ttttttgatt gagggagatt taaatcctga taatagtgat gtggacaaac
      601 tatttatcca gttggtacaa acctacaatc aattatttga agaaaaccct attaacgcaa
      661 gtggagtaga tgctaaagcg attctttctg cacgattgag taaatcaaga cgattagaaa
      721 atctcattgc tcagctcccc ggtgagaaga aaaatggctt atttgggaat ctcattgctt
      781 tgtcattggg tttgacccct aattttaaat caaattttga tttggcagaa gatgctaaat
      841 tacagctttc aaaagatact tacgatgatg atttagataa tttattggcg caaattggag
      901 atcaatatgc tgatttgttt ttggcagcta agaatttatc agatgctatt ttactttcag
      961 atatcctaag agtaaatact gaaataacta aggctcccct atcagcttca atgattaaac
     1021 gctacgatga acatcatcaa gacttgactc ttttaaaagc tttagttcga caacaacttc
     1081 cagaaaagta taaagaaatc ttttttgatc aatcaaaaaa cggatatgca ggttatattg
     1141 atgggggagc tagccaagaa gaattttata aatttatcaa accaatttta gaaaaaatgg
     1201 atggtactga ggaattattg gtgaaactaa atcgtgaaga tttgctgcgc aagcaacgga
     1261 cctttgacaa cggctctatt ccccatcaaa ttcacttggg tgagctgcat gctattttga
     1321 gaagacaaga agacttttat ccatttttaa aagacaatcg tgagaagatt gaaaaaatct
     1381 tgacttttcg aattccttat tatgttggtc cattggcgcg tggcaatagt cgttttgcat
     1441 ggatgactcg gaagtctgaa gaaacaatta ccccatggaa ttttgaagaa gttgtcgata
     1501 aaggtgcttc agctcaatca tttattgaac gcatgacaaa ctttgataaa aatcttccaa
     1561 atgaaaaagt actaccaaaa catagtttgc tttatgagta ttttacggtt tataacgaat
     1621 tgacaaaggt caaatatgtt actgaaggaa tgcgaaaacc agcatttctt tcaggtgaac
     1681 agaagaaagc cattgttgat ttactcttca aaacaaatcg aaaagtaacc gttaagcaat
     1741 taaaagaaga ttatttcaaa aaaatagaat gttttgatag tgttgaaatt tcaggagttg
     1801 aagatagatt taatgcttca ttaggtacct accatgattt gctaaaaatt attaaagata
     1861 aagatttttt ggataatgaa gaaaatgaag atatcttaga ggatattgtt ttaacattga
     1921 ccttatttga agatagggag atgattgagg aaagacttaa aacatatgct cacctctttg
     1981 atgataaggt gatgaaacag cttaaacgtc gccgttatac tggttgggga cgtttgtctc
     2041 gaaaattgat taatggtatt agggataagc aatctggcaa aacaatatta gattttttga
     2101 aatcagatgg ttttgccaat cgcaatttta tgcagctgat ccatgatgat agtttgacat
     2161 ttaaagaaga cattcaaaaa gcacaagtgt ctggacaagg cgatagttta catgaacata
     2221 ttgcaaattt agctggtagc cctgctatta aaaaaggtat tttacagact gtaaaagttg
     2281 ttgatgaatt ggtcaaagta atggggcggc ataagccaga aaatatcgtt attgaaatgg
     2341 cacgtgaaaa tcagacaact caaaagggcc agaaaaattc gcgagagcgt atgaaacgaa
     2401 tcgaagaagg tatcaaagaa ttaggaagtc agattcttaa agagcatcct gttgaaaata
     2461 ctcaattgca aaatgaaaag ctctatctct attatctcca aaatggaaga gacatgtatg
     2521 tggaccaaga attagatatt aatcgtttaa gtgattatga tgtcgatcac attgttccac
     2581 aaagtttcct taaagacgat tcaatagaca ataaggtctt aacgcgttct gataaaaatc
     2641 gtggtaaatc ggataacgtt ccaagtgaag aagtagtcaa aaagatgaaa aactattgga
     2701 gacaacttct aaacgccaag ttaatcactc aacgtaagtt tgataattta acgaaagctg
     2761 aacgtggagg tttgagtgaa cttgataaag ctggttttat caaacgccaa ttggttgaaa
     2821 ctcgccaaat cactaagcat gtggcacaaa ttttggatag tcgcatgaat actaaatacg
     2881 atgaaaatga taaacttatt cgagaggtta aagtgattac cttaaaatct aaattagttt
     2941 ctgacttccg aaaagatttc caattctata aagtacgtga gattaacaat taccatcatg
     3001 cccatgatgc gtatctaaat gccgtcgttg gaactgcttt gattaagaaa tatccaaaac
     3061 ttgaatcgga gtttgtctat ggtgattata aagtttatga tgttcgtaaa atgattgcta
     3121 agtctgagca agaaataggc aaagcaaccg caaaatattt cttttactct aatatcatga
     3181 acttcttcaa aacagaaatt acacttgcaa atggagagat tcgcaaacgc cctctaatcg
     3241 aaactaatgg ggaaactgga gaaattgtct gggataaagg gcgagatttt gccacagtgc
     3301 gcaaagtatt gtccatgccc caagtcaata ttgtcaagaa aacagaagta cagacaggcg
     3361 gattctccaa ggagtcaatt ttaccaaaaa gaaattcgga caagcttatt gctcgtaaaa
     3421 aagactggga tccaaaaaaa tatggtggtt ttgatagtcc aacggtagct tattcagtcc
     3481 tagtggttgc taaggtggaa aaagggaaat cgaagaagtt aaaatccgtt aaagagttac
     3541 tagggatcac aattatggaa agaagttcct ttgaaaaaaa tccgattgac tttttagaag
     3601 ctaaaggata taaggaagtt aaaaaagact taatcattaa actacctaaa tatagtcttt
     3661 ttgagttaga aaacggtcgt aaacggatgc tggctagtgc cggagaatta caaaaaggaa
     3721 atgagctggc tctgccaagc aaatatgtga attttttata tttagctagt cattatgaaa
     3781 agttgaaggg tagtccagaa gataacgaac aaaaacaatt gtttgtggag cagcataagc
     3841 attatttaga tgagattatt gagcaaatca gtgaattttc taagcgtgtt attttagcag
     3901 atgccaattt agataaagtt cttagtgcat ataacaaaca tagagacaaa ccaatacgtg
     3961 aacaagcaga aaatattatt catttattta cgttgacgaa tcttggagct cccgctgctt
     4021 ttaaatattt tgatacaaca attgatcgta aacgatatac gtctacaaaa gaagttttag
     4081 atgccactct tatccatcaa tccatcactg gtctttatga aacacgcatt gatttgagtc
     4141 agctaggagg tgactgatgg ctggttggcg tactgttgtg gtaaataccc actcgaaatt
     4201 atcctataag aataatcatc tgatttttaa ggatgcctat aaaacggagc tgatccattt
     4261 atcagaaatt gatattttgt tattagaaac gaccgatatt gtcttgtcca ctatgctggt
     4321 aaaacggcta gtggatgaga atgtccttgt catattctgt gatgataaac gattaccaac
     4381 agctatgctg atgccttttt atggtcgtca tgattcgagt ttacagcttg ggaaacaaat
     4441 gtcctggtca gaaacagtca aatcgcaggt ttggacgacg attattgctc aaaagatttt
     4501 gaatcaatct tgctatctag gagcatgctc ctattttgaa aaatcccaat ctattatgga
     4561 tttatatcat ggtttggaaa attttgatcc gagtaatcga gaagggcatg cagcgagaat
     4621 ttattttaat acactttttg ggaacgattt ctcaagagat ttggagcatc caatcaatgc
     4681 aggtctggat tatggttata ctttattatt gagtatgttt gcgcgtgaag tggttgtgtc
     4741 tggatgtatg actcagtttg ggcttaaaca cgctaatcag tttaatcagt tcaattttgc
     4801 tagcgatatt atggaaccat ttaggccttt agtggataag attgtttatg aaaatcgaaa
     4861 tcagcctttt cccaaaataa agagagagtt atttactttg ttttcagata cattttcata
     4921 taatggtaaa gagatgtatc tcacgaatat tattagcgat tatactaaaa aagttgtcaa
     4981 agctctgaat aatgaaggga aaggagttcc tgaatttagg atatgagtta tagatatatg
     5041 agaatgatac ttatgtttga tatgccgacg gacaccgctg aggaacgaaa agcctatcga
     5101 aaatttcgga aatttttact tagtgaaggg tttatcatgc atcaattttc tatttatagt
     5161 aagttgctgt tgaataatac agctaacaat gccatgattg gtcggctgag ggagcataat
     5221 cctaataaag gaaatattac attactaacg gtcacggaaa aacagtttgc acgaatgatt
     5281 tatttacatg gtgaaagaaa taattgtatt gcaaactccg atgaaagact tgtatttctt
     5341 ggggaggctt ttgatgaatc ttaatttttc cttactagat gaaccgattc cattaagagg
     5401 cggtacaatt cttgtgctcg aagatgtctg tgtattttca aaaatagtgc aatattgtta
     5461 ccaatatgag gaagattctg aacttaaatt ttttgatcac aagatgaaaa caatcaaaga
     5521 atcagaaatc atgcttgtaa cagatatttt aggatttgat gttaactcct caaccatttt
     5581 aaaattgatt catgcagatt tagaatctca atttaatgag aaacccgaag tgaaatcgat
     5641 gattgacaaa ttggttgcta cgattacaga actgattgtc tttgaatgct tagaaaatga
     5701 attagattta gagtatgatg aaatcacaat cctggaattg attaagtcct taggagtaaa
     5761 agtagaaacg caaagtgata ctatttttga aaaatgtcta gagatacttc aaattttcaa
     5821 atatctcact aagaaaaagt tgcttatttt tgtcaatagc ggagcttttc taacaaagga
     5881 tgaagtggct agtttacaag agtatatatc attgacaaat ttaacagttc tctttttaga
     5941 accacgtgaa ctatatgatt ttccgcagta tattttagat gaagattatt tcttaataac
     6001 taaaaatatg gtataatact cttaataaat gcagtaatac aggggctttt caagactgaa
     6061 gtctagctga gacaaatagt gcgattacga aattttttag acaaaaatag tctacgaggt
     6121 tttagagcta tgctgttttg aatggtccca aaacgggtgg ttggctgacg catcgcaata
     6181 ttaagtttta gagctatgct gttttgaatg gtcccaaaac aggaatatcc gcaataatta
     6241 attgcgctct gttttagagc tatgctgttt tgaatggtcc caaaactaaa tttgtttagc
     6301 aggtaaaccg tgctttgttt tagagctatg ctgttttgaa tggtctccat tcaacattgc
     6361 cgatgataac ttgagaaaga gggttaatac cagcagtcgg ataccttcct attctttctg
     6421 ttaaagcgtt ttcatgttat aataggcaaa agaagagtag tgtgatggaa caaacatttt
     6481 ttatgattaa gccatatggg gttaagcaag gggaggtagt tggagaggtt ttacggtgga
     6541 ttgaacgcct aagatttacg tttaagcgat tcgagccaag acaagctagt tcgaaatact
     6601 tggctaagca cgacgaggcc ttggtgataa accttttgat cctaaactta aagcttacat
     6661 gacaagtggt cctgttttaa ttgggataat tcttggggac taaggtggtt ttgtcttttt
     6721 gaaccatgat gagagtaacc aatcctaagg atgctctttg cggaaccatt cgtgagaatt
     6781 ttgctcaggc tcctggtgat gatggaggta tttttaacat ggtgcatggg tctcattcaa
     6841 gagactctgc taggcgtgag atcgctcttt gatctcatca aagtaatctt ggtagctccg
     6901 ctattctctt gcaagataat ccgtaagaaa agataggcaa aggcctacct tttttgttat
     6961 aatagaagga aagactaaat gtataggaaa atagaatgaa cagtcaagat ttaaaaaaac
     7021 gtcaggagaa gattcgtaat ttctccatta tcgcacatat tgaccatggc aaatctactc
     7081 tcgctgaccg cattttggaa aagacagaga cggtttcgtc tcgtgaaatg caggctcagt
     7141 tattggactc catggatttg gagcgtgagc gtgggattac catcaagtta aacgccattg
     7201 agcttaatta cacggctaaa gatggggaaa cctacatttt ccaccttatt gataccccag
     7261 ggcatgtgga ctttacttat gaagtatcgc gttcgttggc agcctgtgag ggagcgattt
     7321 tagttgttga tgcagcgcag ggaattgaag cgcagacatt ggctaatgtt tacctagccc
     7381 ttgataatga tttggaaatt ttaccggtta tcaataaaat tgatttgcct gctgctgacc
     7441 ctgagagagt ccgtcatgaa gtagaagatg tcattggact tgatgcttct gaggctgttc
     7501 tggcatcagc caaggctggt attgggatcg aagagattct tgagcaaatt gttgagaagg
     7561 ttcctgctcc tacgggtgat gtggatgcgc ctttacaggc cttgattttt gactctgtgt
     7621 atgatgctta ccgaggggta attttgcagg ttcggattgt gaacggtatt gtcaagcctg
     7681 gcgataaaat ccagatgatg tctaatggaa aaacctttga tgttacagaa gttgggattt
     7741 tcactcctaa ggcagttgga cgagatttcc ttgcgacggg agatgttggt tatgttgcgg
     7801 cttctatcaa aacggtagca gatacccgtg tgggggatac ggtgacttta gctaataacc
     7861 ctgctaagga agccttgcat ggctacaagc agatgaaccc gatggtcttt gcagggattt
     7921 atccgattga atcaaataaa tacaatgact tgcgtgaagc acttgaaaaa ttacaactga
     7981 acgatgccag tttacagttt gaacccgaaa cgtcacaagc gcttggattt ggttttcgat
     8041 gcggtttttt aggcttgctt cacatggatg tgattcaaga acgtttggaa cgtgaattta
     8101 acattgattt gatcatgaca gcaccatctg tagtctacca tgttcacaca acagatgagg
     8161 acatgattga agtgtctaac ccttcagaat ttccagaccc aacacgggtg gcttttattg
     8221 aagagcctta tgttaaagcg caaatcatgg tgccacaaga gttcgtaggg gctgttatgg
     8281 aattatcgca gcgcaagcgt ggtgattttg tgaccatgga ttacattgat gataaccgtg
     8341 tcaatgtgat ctaccaaatc ccgctggctg aaattgtgtt tgatttcttt gataaattga
     8401 aatcctcaac gcgaggctat gcgagttttg attatgacat gtcagaatac cgcaggtcac
     8461 aattggtgaa aatggacatt cttttgaacg gtgataaggt cgatgcgctc agctttattg
     8521 ttcataaaga atttgcttat gaacgcggga aaattattgt tgagaaattg aaaaaaatca
     8581 ttccacgtca acagtttgaa gttccgatcc aagccgctat tggtcaaaaa attgttgcgc
     8641 gttcagacat caaggccctt cgtaaaaacg ttttagcgaa gtgttatggt ggtgacgtgt
     8701 ctcgtaaacg taaattgctc gaaaaacaaa aggctggtaa aaaacggatg aaggctattg
     8761 gttctgtcga agtccctcaa gaagccttct tgagtgttct ttcaatggat gacgatacca
     8821 agaaataacc aagcctaatc gcttagtctt cagaggagaa ctcttgtggg tctacatgac
     8881 caaaaaatgg ttatcttata caaaaagaac tttacaatca ttcgcacata atgttataat
     8941 aatattataa tgttatctca ttattaggtg ggtctacatt taatattatt aaagaaaaaa
     9001 gaggaaacaa aaactgtgaa caaaacaaaa caaaacatag ccttctttgt cgctatggct
     9061 taacctcagc ggctgctctt ttgctgacct ttggaggtgc aagtgcggtt aaggcggaag
     9121 aaaatgaaaa agtaagagag caagaaaagc tcatacagca actttctgaa aagctagtgg
     9181 aaattaatga cttacaaact ttaaatggtg ataaagagag tatacagtct ctcgtagatt
     9241 atctgactcg aagaggaaaa cttgaagaag aatggatgga atatttgaat tctggtattc
     9301 aacgcaaact ttttgttggt ccaaaaggac ctgcaggtga aaaaggagaa caaggtccta
     9361 ctggaaaaca aggcgagcgt ggtgagaccg gccctgcagg tccacgtggt gacaagggcg
     9421 aaactggtga caaaggagcc cagggtccag taggtcccgc tggcaaggac ggccaaaacg
     9481 gtaaagatgg tcttccaggt aaagacggca aggacggcca aaacggtaaa gatggtcttc
     9541 caggtaaaga cggcaaggac ggccaagacg gtaaagatgg cctcccaggt aaagacggta
     9601 aggatggcca agatggcaaa gatggtcttc caggtaaaga cggtcaacca ggtaaaccag
     9661 ctcctaaaac accagaggtc cctcaaaacc cagatactgc accacatact ccaaaaaccc
     9721 ctcggatccc tggtcaatca aaagacgtga cacctgctcc tcaaaaccct tctaatagag
     9781 gtctaaacaa accacaaaca caaggtggta atcagctcgc aaaaacaccg gcagctcacg
     9841 acacacacag acaattgcca gcaacaggcg aaacaaccaa tccattcttt acagcagctg
     9901 ctgtagctat catgacgaca gctggagttg tagctgttgc aaaacgtcaa gaaaacaact
     9961 aatcctcttt ttgctaccta actgatggaa agtaaaactc agagagaacc tcaaggttct
    10021 ctcttttttg aatcaagata gtagctctag gtataacgtc ttgtctgagg tgctgtgaac
    10081 aaatcagtta ccgctcacct ctttttttgg taaaatgtaa gcactaaaac atcaaaagga
    10141 gttttccatg gaaacatcag atgagttaaa acaacgcatt ggtgatcttt cttacgaggt
    10201 cacccagcat gcagcaacag aatctccctt tacaggagaa tatgataatt tttttgagaa
    10261 gggtatctat gtcgatatcg tcagtggtga ggtcttgttt tcatcactgg ataaatttaa
    10321 ttctggctgt ggttggcctg ccttttcaaa acctattgaa aatcgtatgg tcacaaacca
    10381 cgatgactct tcttatggga tgagacgagt tgaggttaaa agccgtgaag caggatcgca
    10441 tttggggcat gtctttagtg acggccccaa agaagctgga ggcttgcgtt actgtatcaa
    10501 ttcagcagct cttaaattta ttccttatga ccagatggaa aaagaaggct atgcccaatg
    10561 gctcacattg tttgatgaga cataacaggg tttcaaaatg actgaaattc ccacaagcac
    10621 tggattggtg aggcgtacgg gtcagtttta caagcctttg taaaaggtct ataataggga
    10681 atgaaaaaag gaggttagta tgtcaactca cttaagaaaa cttccagggc tgttactttg
    10741 cttattgtta gctcttccag cctggtgttt agggcgctta tttcccatta ttggagcacc
    10801 tgtttttgct attcttttag gaatgttgtt agccttgttt tatgaacatc gtgacaagac
    10861 taaagaggga attagtttta catccaagta tattttacaa acagcagtgg ttttgcttgg
    10921 ttttggatta aacctaaccc aagttatggc agtgggcatg cagtctttac cgattatcat
    10981 ttcaactatt gcgacagctc ttttggtagc ttatggctta cagaaatggc tgcgcttaga
    11041 tgtcaataca gccaccttgg taggtgtagg atcttccatt tgtggggggt ctgctgttgc
    11101 agcgacagct cctgtcatta aggcaaagga tgacgaggtt gctaaggcaa tttcagtcat
    11161 ttttctcttt aatatgttag cagctttgct atttccaagt ttaggacaat tactaggctt
    11221 atctaatgaa ggttttgcta tttttgccgg gacagctgtt aacgacactt cttccgtgac
    11281 tgcaacggcc acggcctggg atgcccttca ccattccaat acactagatg gagcaaccat
    11341 tgttaaattg actcgcacct tggctattct cccaattact ttaggtttat ccctttaccg
    11401 agcgaaaaaa gagcacgaca tcgttacaga agaaaacttt agccttagga agtcattccc
    11461 tcgtttcatc ctcttctttt tattagcttc tctcatcaca acattgatga ccagtttggg
    11521 agtttctgcc gatagtttcc attacctaaa aaccttatca aaattcttta tcgtgatggc
    11581 tatggcagcg attggtttaa acacaaacct ggttaaactg attaagacgg gcggtcaggc
    11641 tatcctttta ggagctattt gctgggtagc tatcaccctt gtcagtttag ccatgcaatt
    11701 aagtttgggc atttggtaat cagacacgag aaatcagttt gactgatttc tttttttgta
    11761 tcttatttgt gtagaattgt ctacatttta aagagaataa tgcattttta aaacgttttc
    11821 atttgataaa ataaacctat cgttaaacca gttcagtaag gacaactggt tgagataagc
    11881 aattaccgtt tactcagcgg tttttgttaa tagaggagga taggaatgaa acgaaaattt
    11941 ctcattggga gtcacggcag actagccagt ggtttgcaaa gctctattga cattttagca
    12001 ggtatgggac aggcacttga aaccattgat gcttatgttg atgatagtga ctacactagc
    12061 cagattgatg actttatcgc tggggtagca gcagatgagc agggccttat ttttactgat
    12121 ttgttaggcg gcagtgtgaa tcagaaaatg gtaaccgctg taatgaacag tggcaaagac
    12181 aatatctttt taatcacaaa cagtaactta gccactttat tgtcgttggt gtttttaaaa
    12241 ccaggcgaag cgcttactaa agatgaaatt gtaaccgtta tcaatgaatc gcaagttcag
    12301 ttagtggatt tggtccctga gacaaattca gaagatgact tttttgatta atatctagga
    12361 ggaagacaaa tgattaccca aattcgtgtt gacgaccgtt tgattcacgg gcaagtggca
    12421 gttgtatgga ccaaagagtt aaatgcgccg cttttagtag tggctaatga tgaagctgca
    12481 aaaaatgaaa tcacacaaat gacgcttaaa atggctgtgc caaacggcat gaaactgctt
    12541 attcgttcag ttgaagactc gattaagctc tttaatgatc cacgcgccaa agacaagcgt
    12601 atctttgtga ttgtcaattc tgttaaagat gcttgtgcca ttgctaaaga agttccagac
    12661 ttagaagctg ttaatgtggc taatgtgggg cgctttgata agtcagaccc agcaagcaaa
    12721 gtcaaagtga caccaagtct tttacttaac ccagaagaaa tggcagccgc aaaggaatta
    12781 gtcagtttac cagaacttga tgtctttaac caagtcttac catcaaatac caaggtccat
    12841 ttgagccaat tagtcaacta aagagaggta aaaaagtatg ttagtaccag caacaatggc
    12901 agctttagct gtattgattt gttttggggg aaattattta accggtcaaa gcatgatgga
    12961 aagaccccta gtagttggac tggtcacagg tcttctttta ggagatatga aggtcggtat
    13021 cttaatgggg gcctctctag aagctctttt cctaggaaat gtgaatattg ggggtgttat
    13081 tgcagctgag cctgtaacag cgactgccat ggcaacaacc tttaccatta tttcacatat
    13141 tgaccaaaaa gcagccatga ccctagctgt tccaattgga atgttggcag cctttgtggt
    13201 tatgtttttg aaaaacgtct tcatgaatat ctttgctcca atggttgata aagctgcagc
    13261 agctaaccat caaggtaaac tagtgatgct ccactatggc acttggatta tctattactt
    13321 aatcattgcc tctatttctt tcattggtat cttagtaggt agtggacctg ttaatgcctt
    13381 tgtggaacac attcctcaaa atctcatgaa tggcttgagt gctgcgggag gccttcttcc
    13441 agctgtcggt tttgccatgc tgatgaaatt attgtggacc aacaaattag ctgtttttta
    13501 cctattgggc tttgtcttaa cagcttattt gaaattacca gcggttgcag ttgctgccct
    13561 aggagcagtt atttgcgtca ttagttccca acgtgatcta gaattagacg caattactag
    13621 aggtgcaatt agtaaacaaa caacctttga ctctaaagaa tcagaagagg aggacttctt
    13681 cgcatgacat cacaagataa tttgactaaa gaagaccgta aaatgcttcg ctcagtcttt
    13741 tggcgctcat ggacgatgaa tgctagtcgt actggggcaa cacaatacca cgcagtaggg
    13801 gttatttaca ctttactacc agtcatcaat cgtttttata agactgataa ggataaagca
    13861 gaggcactgg tccgtcatac aacatggttc aatgccacca tgcacatcaa taactttatc
    13921 atgggtcttg tggcatcgat ggaaaagaaa aacagtgaag atcctgattt tgatgctagt
    13981 gctattacgg cggtaaaagc atctctaatg ggacctatct ccggagttgg agattccttc
    14041 ttctggggaa ttttaagggt tattgcggca ggtatcggga tttccttggc aagtgcaggc
    14101 tcagccatgg gagctgttgt cttcttactc ttgtacaata ttcctgcttt tattattcac
    14161 tactatagcc tttatggtgg ttattctgta ggtgcaggat ttatcaaaaa actttacgaa
    14221 tctggtggta taaaaatcgt cactaaaacc tcaagtatgc ttgggttaat gatggtaggc
    14281 tcaatgacgg cttcaaatgt aaaatttaaa acgattctta cagttgctgc gaaaggtgcc
    14341 aaagaagcag cttctattca agattacctt gaccaattgt ttattggtat tgtaccatta
    14401 atggtaacac tagcagcttt ttggcttcta cgaaagaaag tgaatatcaa ctggattatg
    14461 tttggtatca tgttccttgg cattatcctt ggacttttag gtatttgcta ataatctcct
    14521 agcaataaag gtaagtaaga caagttttct tgttttgctt acctttttcc ttttaagatg
    14581 atgagacttg ttttgatgaa aaacgtagta gcattaagaa atttgttata atgaaaggag
    14641 cttaagatgc gaggtgaaca ggtggaagaa cattttaaaa aacaattaca agatgatatt
    14701 tctagacatt tttcgtacca atcgttaatg ttatcattgt tgctaattgg tctttttatt
    14761 attttttcat tagcgccaca acaattaggc ctctatcgtg atatcaatgc cactgcaacc
    14821 cgttatcacc gtttgattag caaacaagaa gccttgctgg atgacttagg gaaaaatagc
    14881 ttactacctt ttttaaataa aaacctcagc actgctgatt taagcaagca ctattttcat
    14941 ttgcgccata gcagccaaac gtcaccagaa cttttactat tttcacctag tcaagacctt
    15001 ttatttgcta gtaacccaca tttaggaaat gtttttagta aatctgttta tattcaagaa
    15061 gtcttgagag caactcatcc tccaaaaacc ttgtttaaag ttgctatgga tagtgaagat
    15121 ggtcactact tgatgatcat taagccaatg atagatcaaa accaactaaa gggatatgct
    15181 tttttagtga tgagtggcaa agattttctt catcctacaa aaacattgac gtcagagttg
    15241 gtcattgctg ataagctgga caatacgttt acgttttcca atcgtgagtt tatagcatct
    15301 agtctagata agatcaatag ccagtattta caccattatt ttgtttttca agataatcga
    15361 gcctttatca caagaaaggt tgccttacaa ggaggtcttt ggctttacat gtataggccc
    15421 ttgattccaa tggtatcggt gatgttattt tcacttattt catcagctgt tatctttgtg
    15481 attttgcaac gtaaatcaag tggtttagct aaccgaattg cagctaaaaa ttcaagagca
    15541 atcaatcaaa tggttagaga tatgagtgcg atctctcggc aagaaaaaag acgtattgac
    15601 cttgagagtc aagatgaatt tcaatattta tctgatcaaa tcaatcaaat ggtagagcga
    15661 ttgcaacagt tacatgataa aacgttagat ttggaaactc aaaaattatt atttgaaaaa
    15721 cggatgttag aagctcaatt caatccgcat ttcctctaca atacgctaga aaccattttg
    15781 attacgagcc attatgattc tgccctaaca gaaaaaattg ttatccaatt gacaaaattg
    15841 ttgcggtata gtctcacgga ttctagcaaa cctgtcttgc tcaaagatga tttaagtgtc
    15901 atcgagtctt atttagtgat taatcaggtg cggtttgaag aattgcaata tagcattaac
    15961 ctatccccag accttgatag tcttgaagtg cctaaattgt tcttgttacc tttgatagaa
    16021 aatgccatca aatatggctt gaaagaacga cacgatgtca agattaacat tgcttgttat
    16081 tatcaagatg accacattat tttttctgtg agagataatg gttcgggaat tgatgctcat
    16141 caccaaaaag tgattcgaga gcaattggaa gctggagagt cacaccatgg gttaattaac
    16201 tcttatcgtc ggcttaagta tcatttttca gaagtatcct tggtttttga tcaaggtgat
    16261 aaacagttta atgttagtta ccatgttaag gagtagtcta tgtacaaatt agtcattatt
    16321 gaagatgaac atattattag gaaatggttg cgatacgcta ttgattataa agctttagat
    16381 attttggtca ttggcgaggc taaagatggc aaagaaggag ctgttttaat caaagagagt
    16441 caaccagata tcgttttaac cgatattaac atgcccatca tgacagcttt tgacatgttt
    16501 gaagtaacaa aagatcaaac ttacgccaaa attattttat ctggctatgc tgattttcca
    16561 aatgcaaggt ctgccataca ctacggtgta cttgaatttt taacaaaacc gattgaaaaa
    16621 gcagctcttt gggaatgtct tcaaaccatt attgctaaaa tagaaaagca aaaggggtct
    16681 aatcaaaaaa cagatgcttg cgtctatatt cccttacccc agatgactga tcagattcct
    16741 gaagtagtca aagatatttt ggagtgggta catgctcatt ttcaagacaa gatcagcacg
    16801 agccgcctag ctcatgactt agggtatagt gagagttata tctatcaaaa tatcaaaaag
    16861 catcttcaga tgcctttaag tgattacatt aatcaatatc ggattaatca ggcaattcaa
    16921 ttgatgcaac aagaaccaga tttaatggta tatgaaatag cacaagctgt aggtatttat
    16981 gactatcgct attttgatag ggtttttaaa aagtatctag gacaaactgt aaaggctttt
    17041 aaagaagagc attttatgaa agataccgat aggagtaagc catgttaaaa ctcaaacgca
    17101 aatggctatt aagctttttg ttagtaataa ttattctagc aatcgttaac gttgcaatgt
    17161 atatattctc atcgtcaaaa aaagatagtg ctaaagaatt agttatcttg actcctaata
    17221 gccaaactat tttaacaggg actattccag cctttgagga aaagtatggg gttaaagtaa
    17281 gattaatcca aggtgggacg ggccaactta ttgatcaatt aggtcgaaaa gataaaccat
    17341 taaacgctga tattttcttt ggtggcaatt acactcaatt tgaaagccat aaagatttat
    17401 ttgaatctta tgtttctccg caggtttcta ctgtcatttc agattaccaa ttgcctagtc
    17461 atcgcgcaac cccatatacg atcaatggca gtgtactgat tgttaataac gaattagcaa
    17521 gaggacttca tattaccagt tatgaggatt tgctacaacc agctttaaaa ggcaaaattg
    17581 cttttgctga tcccaacagt tcatcaagtg ccttctcaca gctgactaat atattgttag
    17641 ctaagggggg gtacacaaac gctgacgctt gggcttacat gaagcgcttg ttggtcaata
    17701 tgaattctat tagggctacg agttcttcag aagtctatca atctgtcgct gagggtaaga
    17761 tgattgttgg gctaacctac gaagatcctt gtatcaacct gcaaaaaagt ggtgccaatg
    17821 tttccattgt ttatccaaaa gaaggaacgg tgtttgtgcc ctcctctgtt gctattatca
    17881 aacatgcgcc aaacatgaca gaggctaagc tctttattaa ttttatgtta tcacgtgatg
    17941 tgcaaaatgc ctttggccaa tcaaccagta accgacccat tcgtcaagat gcccaaacca
    18001 gtcacgacat gaaagcctta gaaacgatag ctactttgaa agaggattat gcttatgtta
    18061 ccaagcacaa gaaaaaaata gtggctacgt acaaccagtt gcgccaacgg ttggaaaaag
    18121 ctaagtagga gttaaaagta tggtattgtc aacttgaaaa aggtcctaag gccttttttc
    18181 tatgttataa ttaagaatca tcttcagttg agaaagtaag gattatgcca ccaaaaacta
    18241 ttgatattga aaagtaccac cagcttgctt ggcaaaggca ggctgaacac cgaaagtttt
    18301 tagcgacttt aaagaaaaaa ccacctaaac atctagacaa aattgtccag gacattcatc
    18361 aggaggtttt tcaagagatt gattgcacgt cctgtgctaa ttgttgcaaa gaccttggac
    18421 ctgatttgac agagaccgat attgtcaaaa tcgctaaact attccgaatg aaattagcga
    18481 cttttgaaaa gacttacttg cgcgtggatg aggatgatga taaggttttc cggttcatgc
    18541 cctgtccttt tttaggaggg gataaccttt gaagcactta tgatgtaagg cctaaagctt
    18601 gccgagaatt ccctcacaca gaccgtaaaa aaatctacca gattaatcac ctcacttcaa
    18661 gaacaccttg atttgtccag ccacctacga gtttgtggag cggttaagca aacgtttgac
    18721 ccgttcttag gctagaaaaa ggtgttcttg tagtagaaag tgtatttatt atcacttttg
    18781 acaaaaaatc tctttcccta attgttctaa agaggcgaca atccttaatc actgttaaca
    18841 aacagttaac cgataagtgg attaaggttt gtcatctcaa ataaaatacc ctcaaaagga
    18901 gaccttatga ccacagaatt tgacaaaatg actagaggcg aatggtatga tgctaatttt
    18961 gattcggaac tgattcaaaa acgcatgatg gcacaagacc tctgtttcga tttaaaccaa
    19021 ttaaagccta gtcgagaaga agaacgctct gccgttttaa accaactttt tggacaatct
    19081 tttgagggct tggtcctgct cagccctttc atctgtgact atggtaagaa cattactttt
    19141 gggaagaatt gctttattaa cagcaattgt tatttcatgg atggggcgaa gattgccttg
    19201 ggcgataatg tctttgtagg tccttcgaca ggtttttaca cggcaaatca ccctctagat
    19261 tataaacgcc gcaatgaggg gcttgaaaaa gctttaccaa ttaccatagg agataatgtc
    19321 tggtttggtg ccaatgtcaa tgttatgccc ggcgttacta ttggcagtgg ttgtgtgatt
    19381 gcgtcaggat cagttgttac ccatgatatt ccagtcaatt cccttgcggc aggtgttcct
    19441 tgccaagttg tacggaaaat tgagcaggag tagaaagtga ggcaaaaagt gcattacaac
    19501 tttctttttt tcgaccttga ccatacccta cttgattttg atgcggcaga agaggttgct
    19561 ttgaccaagt tgctagaaga gtaccaggtt attgatatta aggcttacaa ggactactat
    19621 aagccgatga atcagaactt atggaaacag ttagaaggtg gggatattag taaagctgat
    19681 ttggttaact ctcgctttgc tctgctattt gctcattttg gagtgacggt tgatggcagg
    19741 cagttagcag aaggttatca aaagcattta aaagatcaag ggcaagttta tgctggtgct
    19801 aaggagctgt tagcggactt aactgcccaa ggctataatc tttatgcggc aactaatggc
    19861 atcgcaacga ttcaacaagg ccgattgcaa gcgtctggtt tggcacctta cttcaaagcc
    19921 attttcattt cggaacagtc gggtagtcaa aaacctaaaa aagctttcta tgattggatg
    19981 acccagcagg tttccaatta ccaacctgat caagctttga tgattggtga tagtttatcg
    20041 gctgatgttc aaggtggaat taatgctggc atggatacct tatggtacaa cccaaagcat
    20101 ctcctgaata acagccctgt tcatcctacc tatgaggtgt cagattatca agctctgctg
    20161 aattgtattg cggagtaaca gacaatagcc tttaaaaata gcgtagtcat tttttgaaat
    20221 cgatttcata atctggtaga ctaaggttat cacgaaaagg aggctatatg tgatggctta
    20281 tcaaactatt tacccttata caaatgaagt ccttcataca tttgataata tgaccgatca
    20341 aggtttggca gatgtccttg aaagagctca ccttctctat aaaaaatggc gcaaggaaga
    20401 tcatttagaa gaacgtaaag cccagcttca tcaagtggct aatattcttc gtcgtgaccg
    20461 cgataaatac gctgaaatca tgaccaaaga catgggaaaa ctgttcacag aagcccaagg
    20521 tgaagtaaat ctttgtgccg atattgctga ttactacgct gataaggcag atgaattttt
    20581 gatgtctacg ccactagaaa cggattcagg tcaagcttac tatttgaaac aatcaactgg
    20641 tgttatccta gctgttgagc cttggaattt tccttactat caaatcatgc gggtctttgc
    20701 gccaaacttt attgttggaa acccaatggt tttaaaacac gcgtccattt gcccacgctc
    20761 tgcccaatct ttcgaagaat tagttcttga agctggtgct gaagcaggta gtattaccaa
    20821 tttgtttatt tcttatgacc aagtatcaca agtgattgct gataaacgtg tggttggtgt
    20881 ctgcttgaca ggttccgaac gtggaggagc tagcattgca gaagaagctg gtaaaaactt
    20941 gaaaaaaaca acccttgaat tgggtggaga tgatgccttt attatccttg atgacgcgga
    21001 ttgggatcaa ttagagaagg tgctttactt ctctcgtctc tacaatgcag gtcaagtatg
    21061 tacctcatcg aaacgtttta tcgtgcttga caaagactat gaccgtttca aagagttatt
    21121 aacaaaagtc ttcaaaacag ctaaatgggg tgacccaatg gatcccgaaa cgacgttggc
    21181 gccattatca tcagctcaag ctaaagcaga tgttcttgac caaattaagt tggccttgga
    21241 tcatggtgcg gagttggttt atggtggtga agcgattgat catccaggtc attttgtcat
    21301 gccaaccatt attgctggcc tcacaaaaga caaccctatt tactatcaag aaatctttgg
    21361 cccagtcggt gaaatctaca aagtgtcttc tgaagaagaa gcgattgaag tggcgaatga
    21421 ttctaactat ggccttggag gtactatctt tagtagcaat caagaacatg cgaaagccgt
    21481 agctgctaaa attgaaactg gtatgtcttt tatcaactca ggctggacaa gtcttccgga
    21541 actcccattt ggtgggatta aacattcagg ctatggtcgt gaattgagtg agcttggctt
    21601 tacatctttt gtgaatgaac accttatcta tattccgaat aaaacgaata atggcaatac
    21661 taaagtttga tctagattgt taaaggagat ctgctcgcct taataaacaa tcaaggcgtt
    21721 acactcttct tttttaaagt caaaatttta aaaatttgat aaactagtaa catgaacgaa
    21781 ctgattaaac ataaactaga actcttacca gacagccctg gctgttactt acataaagat
    21841 aaagaaggaa ctattatcta tgtcggtaag gccaagaatt tgaaaaaacg cgtccggtcc
    21901 tattttcgtg ggagccatga taccaaaaca gagttactag tatctgagat tgtagatttc
    21961 gaatatattg taacagagtc agataccgaa gcgcttttgt tggaaattaa cttgattcaa
    22021 aaaaatatgc ctaagtacaa catcaagtta aaagatgata aatcttatcc ctttctcaaa
    22081 atcacaaatg agtcttttcc tcggttagtg attacaagat atattaagaa aaatgatgga
    22141 ttgtactttg ggccctaccc agattcttac actgctaatg aagttaaaaa gttattagat
    22201 aggatttttc catttaaaaa gtgtaaaaat cctatcaata aggtctgttt ttattaccat
    22261 ttaggccagt gctgtgctca taccatttgt catacagaca aggcctattg ggatcgttta
    22321 attgatgatg ttaagcactt tttaaatggt aaagatgaca aaattattga agatcttcgt
    22381 tctaagatgt tagcagcttc taaagaaatg gcatttgaac gtgccgctga atatcgagat
    22441 ttgatttcag gtattgccac catgcgcacc aagcagcggg tgatgagcaa ggatttgcaa
    22501 gatagagata tctttggcta ttatgttgat aagggatgga tgtgtgtcca agttttcttt
    22561 gtgcgtcaag ggaaattaat tcagcgtgat gttaaccttt ttccctatta taccgatgca
    22621 gaagaagatt tcttaactta tatggggcaa ttttaccaag ataaacagca tttcatccct
    22681 aaagaagtct ttattccaga agctattgat gaagaactgg tagccgctat tgtgccaacc
    22741 aaaatcatca aacccaaacg cggtgaaaaa aaacaactgg tagctttggc tactaagaat
    22801 gctcgtgtta gtctgcaaca aaaatttgat ttattagaaa aagatatcaa aaaaacgagt
    22861 ggtgctatcg aaaatttagg tcagttactt aggattgaca agcctgtgcg cattgaagcc
    22921 tttgataatt ctaacattca agggacaagt ccagttgcgg ctatggttgt ttttgttgat
    22981 ggcaaaccta gtaagaaaga ttatcgtaaa tttaagatta aaacagtggt gggaccagat
    23041 gattatgcca gtatgagaga agtgcttttt cgaaggtaca gtcgggtgaa aaaggaggga
    23101 ctgcaagctc ctaacttgat tattgttgat ggaggcgttg gacaagtcaa tgtggccaaa
    23161 gatgtgatag aaaaacaact tggactcact attcctgttg cgggacttca aaaaaacgat
    23221 aagcaccaga cccatgattt gctttttgga aacccacttg aagttgtacc gttgccgcgc
    23281 cgttctgaag agtttttctt actgcatcgg attcaagacg aagtgcatcg ctttgcagtt
    23341 acatttcata gacaagtgcg acgtaaaaat tctttttcat caacattaga tcatatttca
    23401 gggcttggcc caaagcgaaa acagttatta ctaagacact ttaaaaccat aacagcgatt
    23461 gcatcagcta cctctgagga gattcaagct ttaggtatac ctaaaacagt agttgaagca
    23521 atacagcaac agataacaga caataaaaat gatagatcgt ccccttaaat aagtgttatg
    23581 ttttcagtac tgatgaggta aaaaggcgct acttgttacg cacgacattt cagttcgtta
    23641 ttttgaaact ttcagaaggt tgcgaagtgt agtgagttta tgattttaaa aactatttta
    23701 tggtaaaata aaatggtatt aaaaaaaaca gatttagata ggaagttttg aaatgaaatt
    23761 tctagagtta aacaaaaaac gccatgccat taagaccttt aatgaccagc cagttgacta
    23821 cgaggatttg cgaacagcca ttgagattgc aaccttagca cctagtgcca ataacattca
    23881 accttggaaa tttgtagtcg ttcaagagaa aaaagctgag ttagcaaaag ggttacctct
    23941 agcaaataaa gtgcaggttg aacaggctca atatgtagtg gcgctatttt cagacactga
    24001 tttagcttta cgttctcgta aaattgcccg tatcggtgtc aaatcattac cagacgactt
    24061 aattggttat tatatggaga ctttgccacc acgttttgct gcttttaatg aggttcaaac
    24121 cggtgagtac ttagctatta atgcaggcat tgtggctatg aacttggtgt tatccttgac
    24181 ggatcaaaag attgcttcca atattatcct tggttttgat aagtcaacga ccaatgagat
    24241 tttagacatc gatccgcgtt ttcgtccaga attattgatt actgttggct atagtgacga
    24301 gaaaccagaa ccaagttatc gtttgcctgt tgatgaagtc atcgaaagaa gatagagtca
    24361 ggacaattag ttaaatgtaa tgtccagatg cgctactgag cgaccactat tgttagactg
    24421 atactatttt ggcttatttt aagttaaaca ttatccctaa aacgaataag gagagtataa
    24481 tgacaaccat tgattttaaa gcagaagttg acaaacgtaa aaaagctatg ctagcagatt
    24541 tagttgacct attacgcatt aattcagaac gcgatgacca attagctgat gataaacacc
    24601 catttggccc aggtccagtt aaggccttgg agcatttcct cgcaatggct gagcgtgatg
    24661 gctacaaaac gcgtaatatt gataactatg caggtgactt tgaatttggt caaggtgatg
    24721 aagtactagg aatctttggt caccttgatg ttgtgccagc tggtagcggt tgggatacag
    24781 acccttatga gccagtgatt aaagacgatc gcatctatgc gcgtgggtct tcggatgata
    24841 aaggaccaac catggcgtgt tactacgctc tgaaaatcat taaagaactg ggtcttcctg
    24901 tgtctaaaaa agttcgtttc attgttggta ccgatgaaga atctggctgg ggggatatgg
    24961 attattactt tgctcataat ggcttgaaaa atccagattt tggtttctca ccagatgctg
    25021 aatttccaat tatcaatggt gagaaaggaa atatcactga atacctccat ttcgctggtg
    25081 acaacaaggg cgcttttgtg cttcatcgct tccaaggtgg gttgcgtgaa aacatggtac
    25141 cagaatctgc cacagctgtc attacggcac cgcatgacct tgatgtgcta gaagcagctt
    25201 tggagcaatt tttatcagaa catggtgtta aaggttctat gaaggctact gatggtaaaa
    25261 ttgaagtaac tattattggt aagtctgctc acgggtcgac tccagaagcg ggtgttaatg
    25321 gtgctacctt gttggctaaa ttcctgaatc aatttacctt tgaaggggct gctaaggatt
    25381 atttacatgt ggcaggtgag gtgcttcatg aagactttgc ggcagaaaaa ctaggccttg
    25441 cttatactga tgaccgtatg ggagccctga gcatgaacgc aggtgtcttc acctttgata
    25501 gtcaatcagc tgacaatacc atcgccttga atttccgcta tcccaaagga actgatgcgg
    25561 caaccttaaa agcaggattg gaaaaattac caggattaac taaggtaagc ctttctgagc
    25621 atgaacatac acctcattat gtgccaatgg atgatgaatt agtagctacc ttacttgctg
    25681 tttacgaaaa acaaacaggt cttaaaggct acgaacaagt tatcggcgga ggaacctttg
    25741 ggcgcttgct agaacgtggt gtggcctttg gagcgatgtt cccaggtgat gaaaacacta
    25801 tgcaccaagc taatgagtat atgcctttag aaaatattta tcgctcagca gctatttatg
    25861 ctgaagcaat ctacgaatta attaaataag atgcttatga cagcaaaaag agctggaaca
    25921 ctgttccagc tcttttgtga tgattagaga ctgttgttat ttaccaagac agaattgact
    25981 aaagagttgg gtaatgagtt catcaggagc agcatcccct gtgatttctc cgagaatttc
    26041 ccaagttctg gttaaatcaa cctgtagtaa atcaactggc atgccaagcg ccaaaccgtc
    26101 attgacagct tctaaactct ggactgcctt ttcaatcaaa gaaatgtggc gggcatttga
    26161 caggtaagtg gcatcttgct ctaccaaacc agcgttgtca aagaaaagct ggttgatacg
    26221 atcttcgatt agattaatgt tctggttggt taaaacggaa atgggaatgt agtcatctgg
    26281 taattgctct aattcaatct tctgttccaa atccgtttta ttcaacaata taatacggtt
    26341 actgtcctga ctgagattta acaaagcccg gtcttggtca gtcagttttt cagaagcatt
    26401 cagcacaaga agaacaaggt cagcttcttg aagagctttt ttagaccgtt caactccgat
    26461 ttgttcgacc agatcatctg tctcacgaat accggccgta tcgacaagtt ttagaggaac
    26521 tcccttgata ttaacgtatt cttcaatgac atctcgggtg gttcctgcaa tatcagtcac
    26581 aatagccttg tcttctcgca acaaattatt aagtaagctt gacttaccga cgtttggacg
    26641 accaataata gctgttgata agccctcacg cagaatttta ccgcgtttag ctgttcgaag
    26701 gagactttcc aaaaggcttt ggaattcttg tgttttctca cgtagcagag cagtggtcat
    26761 ttcttccaca tcgtcgtatt cagggtagtc aatattgact tcgacttgag ctaaggtgtt
    26821 gagaatttcc tgacgggtgt cattgataag ctgggaaagg gagccatcca gttgcttgac
    26881 tgcaatcgtc atagccttgt ctgttttggc acgaataatg tccatgacag cctcagcttg
    26941 agtcaaatca actcgcccat ttaagaaggc acgtttggtg aattcgccag gctctgccat
    27001 tctagcgcct tggcgaatca atagttgcaa gatttcattt gtcacagcaa taccaccgtg
    27061 cgtattgatt tcaaccacat tttcacgggt aaaggttttg ggggctagca tgactgacac
    27121 cataacttca tcgataatag ttcctgtctt aggattaatg atatggccat agttaatggt
    27181 gtgtgaggcg acttgctcta agttctttcc cttaaaaaca gattgtgcaa tggcaagcgc
    27241 atctgtccct gataaacgaa caatgccaat agctccttca ccaagagggg ttgaaatggc
    27301 ggtaattgta tcaaattctt tagttatact catgccctct attttaaatc aagtcctagt
    27361 agaaagcaag gtgttatttg tatagaaaat aggactagca ccattttgag tttagctaat
    27421 actaaaaaaa taaatgtaaa aaaatcattt tttaatagtt tttattgaca atagtattat
    27481 aaaagaatat aatgatatag gttttgataa aaaactgacc taagacagca ggggagcatg
    27541 ctcataatat tcctgccgag gcacaaaacg tgattaaaga aaataacgta tttgtacttt
    27601 cgtgtctagg tttaggtgcg attttttttg tacctagccc aaaaataaaa acggaggtaa
    27661 aactaatgag tgaagcaatt attgctaaaa aagctgaaca agtcgaactt attgctgaga
    27721 aaatgaaagc agcagcaagt atcgttattg ttgattcacg tggtcttaca gttgatcaag
    27781 atactgttct tcgtcgttca cttcgtgaaa gtggcgttga gttcaaagtt atcaaaaact
    27841 caattttgac tcgtgcagct gaaaaagcag gtcttgatga gttgaaagat gtattcgtag
    27901 gaccatctgc agtagcattt tctaacgaag atgttatcgc accagctaaa gttatcaacg
    27961 actttactaa aactgctgac gcacttgaaa tcaaaggtgg tgcaatcgaa ggcgctgttt
    28021 cttcaaaaga agaaatccaa gcacttgcaa cattgccaaa ccgcgaagga atgctttcta
    28081 tgcttctttc tgtacttcaa gctccagtcc gtaacgttgc atacgctgtc aaagctgttg
    28141 cagaaaacaa agaaggcgct gcttaagtcg tctcagagta gcttaaggct acgcttaaca
    28201 ttttaaatta attatttgga ggaaatcaca atggcattga acattgaaaa cattattgct
    28261 gaaattaaag aagcttcaat ccttgagctt aacgatcttg taaaagctat cgaagaagaa
    28321 tttggtgtaa ctgcagctgc tcctgtagct gctgcagctg ctggtggtgc tgaagaagct
    28381 gctaaagatt cattcgacgt tgaattgaca tctgctggcg acaaaaaagt tggcgttatc
    28441 aaagctgttc gtgaaatcac aggtcttggt cttaaagaag ctaaaggtct tgttgatgga
    28501 gcacctgcta acgttaaaga aggcgttgct gctgcagaag ctgaagaaat caaagctaaa
    28561 cttgaagaag ctggagcaac aatcactctt aaataagaag cagatagcaa tttgagagcg
    28621 aaatcccgat ttatcagtct tttagagttt atagcgattt gaagaaactg ataaattgat
    28681 ttggtttctt gccaaaaatc ctgcccaaaa aatctttggc aggattttta ttttctataa
    28741 aaattaagct gagtagagtg gttattctat ctatatgtgt ctagtaataa tttttttatg
    28801 tgaacgagaa cattttaata agtgttctca tttttttatt ttcaggagga aaatcatgca
    28861 aatgaatgaa cagtcatcac gacaaatggt gattgccatc tatctcattt attccaactc
    28921 aaaatgacag tactccttgg ctgttccaag tcgaaattgt tagcgattaa gaaaacctac
    28981 gagactatgg tttgatcgat gaagtccaac agtctcccag tgaaaaaggg cgtttggcta
    29041 ataagattta tttaggaaag ttggaacatg atttcacccc agtcttaagt tcagacgggg
    29101 ccagtctcaa aaacagacca gccccgtgtt aaattcagcc cctagtgaga ctgaaaagag
    29161 tgaaactgaa ggtagtgaaa ctaaagagag taatttagtg attgaggacg aggaggaaag
    29221 aaaggagtgc actagtgtga aaaagactga gggtcacttt acccgtcaag ttgatcaggt
    29281 caccaaatat gacaaagatt atatttggag tttggttcat tcccaattac gtgaaggtgg
    29341 tttatcacaa gctgctagtg acttagtcat gagctatttt gaagaacgct atgcttatgc
    29401 gctggaacac atacggttcg caagaacagc tgaagctatt gcggaatatg tctttaatgg
    29461 tgtcttatcc gaatggacca agcaactaag gtgacaagaa gcgaagtgag taagatgttt
    29521 tggtggctat tattaggtgt ttggggacta aggacaattt ggttgattat tgaagttatc
    29581 actgcaccag aaatggaaga ttatagttga gtaaggacgt tacataagca gtaaggtcct
    29641 tttattttgt cagaaaggaa tgagagatat gaagttttta gatttgtttg caggaattgg
    29701 aggctttcga ttgggtttaa ttaatcagtg ccatgagtgt attggctttt gtgagattga
    29761 taagtttgcg aggcaatctt acaaagccat ctatgagacc gaaggagaaa tagaatttca
    29821 tgacattaga caagtcacag accaagactt tagacaactt agagggcaag tggatatcat
    29881 ctgcggtggt ttttcccttg tcaagcattt tcactcgcag gcagacgact gggatttgag
    29941 ggcactagga gaactctctt ctttgagatt actcgagcga ccaaacagat aaaaatcata
    30001 cccataatca catccaatca acgccattga ccgtaattca gataaaaaat tgatatggaa
    30061 ttatgccttg gaacgaaacc tccgtatgat ttcagaccgt atttcaaaaa tgactggagc
    30121 aaaaattatc gagaagcgtt attcctaccg tgactatcaa aaatataggt agtctagtca
    30181 taaatttgaa ttgaaacaac gtctttattt tttgatgcag cagtcaaagt tctttgatga
    30241 ttttttagaa aaagcagagt aattacatgt tcatattgat tttagtcaga agcatagcag
    30301 attcatgatg acggatcgag tagtgaaaaa accaattcga ggccgtcaac tcagtaaacg
    30361 agatttatat gatgaagaat tttttcgtac acattttgcc aagatagaaa ttgaaagtcg
    30421 attagaattt ttgttgaacc gtgccaattc attagaggag ctactattaa aagcaaaaga
    30481 agtgaatcta accattgact taaaacaaaa aatgtaactt ttatcctaga agaagatact
    30541 caaaagataa gtttaggtca taaaaaaata agcgataaga aattatatga tgtcaatttt
    30601 ttcaagatta ctttaaaaat aaggaagtcg gtgtttcaga tcgattagaa agtctacaga
    30661 aacagtacat gcttttcaag aagaacgaga taaagaggag gtatccactg aagagagtaa
    30721 ggaagtcttc aagaaataca aggggcaacg agatgccatc catgagtttg aagttgaact
    30781 tgtggaacat caaattgaga ggttaattgc tgaggacatt tatatcaagg tgtcttttag
    30841 tgtaaagcag agtggtctta ttttcattcc taactatcaa ttggatatta ggaaagaaga
    30901 aaatcataaa aaatataaag tctatattcg tgagaccgca caattcttca tttacaacaa
    30961 ggaggcgtct gaacttaatc gctatatgcg agggcatgag ctcatttgcc agttaaccaa
    31021 tgatagcaag agtattccaa aaagaagacg acaaaccatt gatacactta agaaaaagat
    31081 tgaagaaata agtctcctca ttgagttaga tacggagaat aagccttatc aagatattaa
    31141 agatgacatt gttaaagata tggctcaatt agatttgacc attacagagt tgcaggacca
    31201 tattgctcat ctcaataagg ttgcggaggt cttgcttaat ctgaacaaca acgatataga
    31261 gaaccgccgt ttggccagat atgactatgc caagatgaac ttgactgcag ctataaaaat
    31321 agaagaagtt gagaaagaga ttgaaacttc tcaaaatgaa cttaatatat ccatagatga
    31381 gtatgaatat ctagtaagaa ggttggaaaa gtttggagag atcttgagtg atagcaaaat
    31441 tatcgatact tctcgaaatg aaatacaatg ggagtaatta tgatataatt tgggtggtag
    31501 caatttttat
//
LOCUS       DAUGQX010000022        29456 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUGQX010000022 DAUGQX010000000
VERSION     DAUGQX010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29456
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.022"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            394..762
                     /locus_tag="VIA51_000934"
     CDS             394..762
                     /locus_tag="VIA51_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682883.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEESLGQAKEKVEGIGEATSQ
                     TIQSKMEKLTSDKTDADDEK"
     gene            complement(812..1723)
                     /locus_tag="VIA51_000935"
     CDS             complement(812..1723)
                     /locus_tag="VIA51_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8682884.1"
                     /translation="MKTVRIFYNPNSGKKESQLARQVKDYFCQHGFSEDSVKVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAVSIIVPTED"
     gene            complement(1840..2490)
                     /locus_tag="VIA51_000936"
     CDS             complement(1840..2490)
                     /locus_tag="VIA51_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEQ8682885.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(2487..2927)
                     /locus_tag="VIA51_000937"
     CDS             complement(2487..2927)
                     /locus_tag="VIA51_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEQ8682886.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLLQEVTQ"
     gene            3146..3994
                     /gene="ylqF"
                     /locus_tag="VIA51_000938"
     CDS             3146..3994
                     /gene="ylqF"
                     /locus_tag="VIA51_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEQ8682887.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFREYY
                     PNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDAD"
     gene            3984..4775
                     /locus_tag="VIA51_000939"
     CDS             3984..4775
                     /locus_tag="VIA51_000939"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEQ8682888.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKV
                     IQAELAEEERLEAMLSYEKALYKKGYKAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKAKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            4840..5676
                     /gene="dprA"
                     /locus_tag="VIA51_000940"
     CDS             4840..5676
                     /gene="dprA"
                     /locus_tag="VIA51_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEQ8682889.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            5783..7912
                     /gene="topA"
                     /locus_tag="VIA51_000941"
     CDS             5783..7912
                     /gene="topA"
                     /locus_tag="VIA51_000941"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEQ8682890.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGVQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEQWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(7987..8869)
                     /locus_tag="VIA51_000942"
                     /pseudo
     CDS             complement(7987..8869)
                     /locus_tag="VIA51_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            8882..9427
                     /locus_tag="VIA51_000943"
                     /pseudo
     CDS             8882..9427
                     /locus_tag="VIA51_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            9442..10434
                     /locus_tag="VIA51_000944"
     CDS             9442..10434
                     /locus_tag="VIA51_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEQ8682891.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIVLNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNS
                     DLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            10539..11204
                     /locus_tag="VIA51_000945"
     CDS             10539..11204
                     /locus_tag="VIA51_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEQ8682892.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            11197..11913
                     /locus_tag="VIA51_000946"
     CDS             11197..11913
                     /locus_tag="VIA51_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEQ8682893.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILLITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGVCMIMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            12064..13410
                     /gene="trmFO"
                     /locus_tag="VIA51_000947"
     CDS             12064..13410
                     /gene="trmFO"
                     /locus_tag="VIA51_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEQ8682894.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIEVIRGEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            13563..14969
                     /locus_tag="VIA51_000948"
     CDS             13563..14969
                     /locus_tag="VIA51_000948"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEQ8682895.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEASYDITLDETLLEQAA
                     NHLRQARQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            15012..15326
                     /locus_tag="VIA51_000949"
     CDS             15012..15326
                     /locus_tag="VIA51_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682896.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            15326..15676
                     /locus_tag="VIA51_000950"
     CDS             15326..15676
                     /locus_tag="VIA51_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HEQ8682897.1"
                     /translation="MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANA
                     AGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            15686..16816
                     /locus_tag="VIA51_000951"
     CDS             15686..16816
                     /locus_tag="VIA51_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8682898.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLASFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKIGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(17016..17900)
                     /gene="citG"
                     /locus_tag="VIA51_000952"
     CDS             complement(17016..17900)
                     /gene="citG"
                     /locus_tag="VIA51_000952"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEQ8682899.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFI
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(17893..18588)
                     /locus_tag="VIA51_000953"
     CDS             complement(17893..18588)
                     /locus_tag="VIA51_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8682900.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(18746..20149)
                     /locus_tag="VIA51_000954"
     CDS             complement(18746..20149)
                     /locus_tag="VIA51_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEQ8682901.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
     gene            20529..20852
                     /locus_tag="VIA51_000955"
     CDS             20529..20852
                     /locus_tag="VIA51_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682902.1"
                     /translation="MQFLQKWFKHSKKEKLKESSSLSTEIEPSENWAKIPAYIPADKS
                     DYKKVTLITSVIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
     gene            20909..21304
                     /locus_tag="VIA51_000956"
     CDS             20909..21304
                     /locus_tag="VIA51_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ8682903.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            21349..22470
                     /locus_tag="VIA51_000957"
     CDS             21349..22470
                     /locus_tag="VIA51_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8682904.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            22658..22966
                     /gene="citD"
                     /locus_tag="VIA51_000958"
     CDS             22658..22966
                     /gene="citD"
                     /locus_tag="VIA51_000958"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEQ8682905.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
                     "
     gene            22954..23841
                     /gene="citE"
                     /locus_tag="VIA51_000959"
     CDS             22954..23841
                     /gene="citE"
                     /locus_tag="VIA51_000959"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEQ8682906.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDII
                     DVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            23844..25376
                     /gene="citF"
                     /locus_tag="VIA51_000960"
     CDS             23844..25376
                     /gene="citF"
                     /locus_tag="VIA51_000960"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEQ8682907.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEELVEKILDVQDFDHP
                     SAVSLGKHAEHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVIVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            25369..25947
                     /gene="citX"
                     /locus_tag="VIA51_000961"
     CDS             25369..25947
                     /gene="citX"
                     /locus_tag="VIA51_000961"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEQ8682908.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            25962..27356
                     /locus_tag="VIA51_000962"
     CDS             25962..27356
                     /locus_tag="VIA51_000962"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEQ8682909.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLTDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVITCRPADLIEPQMIYLRDEIAPYAHSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(27466..28518)
                     /gene="citC"
                     /locus_tag="VIA51_000963"
     CDS             complement(27466..28518)
                     /gene="citC"
                     /locus_tag="VIA51_000963"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEQ8682910.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(28607..29089)
                     /locus_tag="VIA51_000964"
     CDS             complement(28607..29089)
                     /locus_tag="VIA51_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEQ8682911.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTINDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
BASE COUNT         9204 a         5583 c         5951 g         8718 t
ORIGIN      
        1 aatataagtt aataactgtg ttgtcacttt gttgaaatgt tttcgtatta atgttttttt
       61 atctattgcg atagataatt ttacttcaat ttttgattga aaatactaaa ataagtgatg
      121 tggtcacttt gacaaccatt tattggtcct tttagataag acaattttgt ggctcttcag
      181 ttgaaaggat gtgttgttga tgttagagga aacaatcatg ttaaattaac tcaggcttaa
      241 agaccaaaaa aggagtgaag tctattatga aaaaaagaaa ttttaaactt acagaaatgt
      301 tacaattggt tttattagtg gttcctgctg taaaacttgc taaaaaaatg tttaacgata
      361 gtaaaacacc gtctaaaaga aagtaggtct acaatgacta aaaaaaatca tggcgttttt
      421 tgggggttgt tgcttggatc agcagcagct agcattgctt acttaagttt atcgtcttcc
      481 aaaaaagatc aactcttgaa agatagtgct aaaaaaatag atgatctcaa cgcttacttg
      541 caagataaaa gtaagcaagt tctggatgca gtatcggaaa aagtccaaga atccaaagat
      601 gctgttgaag tttacggtgg tatcgccgca gaaacagttg aagaatcttt gggacaggct
      661 aaagaaaagg tagaaggaat tggcgaagct actagccaaa ctatccaatc taaaatggaa
      721 aaactcacta gcgataagac agatgctgat gatgaaaaat aggttttaaa atacctttaa
      781 gataagacaa aaagtgccat taggcacttt tttaatcttc tgttggaaca ataatcgaaa
      841 cggcttttgg aatgatatct aattgaatgg gcagatagtc acttttatcc ccatcaatcc
      901 tggtacgtgg taatatcgct tgttttttag cttgtggtag taagctaagc gtattggctt
      961 gaaaatgact gatttcctct gctttggaaa aatcaccctg tttaaaatca ttaatatgcc
     1021 ataaaaattt aaagaaagag acttttttca tggtataaac ttggaaatag ccatcgtcag
     1081 cttgagcacc aggagaaaaa gaaggaaaac cagcaatggt atttgtcatc gtgattaaga
     1141 gaaacttcgt tttcaggtga atacgatggt tgtggctaat taaagagatg gcatagctgc
     1201 gatttcgttt cagtattcga atactatctt ttaaaaatgc tagaggacca aagcgtcgtt
     1261 tttcctcagc cgttacgtcg gcagcaatat cagccagtaa tcctaaagtt aaactggaaa
     1321 tcatgtattg ctggttagct ttgcaaatat caacttgctt gatttgtcca gtcaagatag
     1381 tatccaacgc ctcagtaatt tgtaaaggga tatgcatagc cttggcaaaa ttattgactg
     1441 tccctgaggg cactaagcct attaaacaat gagctcctcc ttcatagatg ccaccgatga
     1501 ttttatttag tgtcccatcg ccaccaagag ggataaccaa gtcaatcttg tccttagcag
     1561 cttgttttgc taattgaaaa gcctggtcag catctttagg ggtaataact tttacagaat
     1621 cttcggaaaa accatgttgg caaaaatagt ctttgacttg cctagcaagt tggctttctt
     1681 tctttccaga attaggattg taaaaaatcc gaacggtttt catcaggtct ctcctttgac
     1741 agcttattac ttgctatcca ttataccact tctaagaatt gatgtcttac atcaaatcat
     1801 cacattaagc ctctcaatca gtctgagcat ctatttgtct taaagcataa agaaagtgat
     1861 agcgataaat tggagggcag aggccaataa aataaagaga tgccaaatca tgtggaagta
     1921 gggtcttttt ttggcataaa ataccgctcc aatggtataa gacaagccac caaataacat
     1981 gagaagacca aaagcaagac tagttttttg aatgatgact ggcaagataa acacaacgag
     2041 ccagcccata acgatataaa gcatcaaact gaatttttca ttgatacgtt tggcaaaaat
     2101 tttgtataaa atcccaaaaa gcgtaatgcc ccactgcaaa acaataatga tatagcctag
     2161 ccaaccagaa acaagggata aggcaacagg tgtataactt cctgcgatag caatataaat
     2221 catactgtga tcaataatgc gtagaatgta tttgtgaacc gaaccataag ccatggagtg
     2281 gtaaatcgta gaggacaaaa acatcaaaaa gagactgatg acaaagatgg agataccaat
     2341 agcggcttta aggtcataag tttgataagc atagctggct gaaataggaa gtagaatgag
     2401 catagcaaat gctccgatag cgtgtgtcac gctgtttgct acttcctcac taaaagataa
     2461 gggtaaactt tgtttaaagg tttggttcat tgggtcacct cctgtaataa ataaatagtt
     2521 ttgtggtaat ctttgaccgt ttgacaggca acctgcacaa tcggtggaat gtcctcctca
     2581 atgggagcct tctgattcca acaggttaca aaagtattgt aaagactttc agaatcagcc
     2641 tgtgcctgaa gttcctccaa tacgcgacta atatcttgaa taggaaatac cgttttaaac
     2701 aaactgatgg caattaagcg cgctagttgt tgcttttggt attttttctt gataggttta
     2761 gtcacatacc catgcttgac gtaattatta atcatagatg ccgttagtga tttattatct
     2821 gacacttctg aaaaatcagt gcactggttg acataaagta acacttgatc caaatataag
     2881 tctaaatcag ggaggtcctt ccaataaggt aatgatggaa aaatcatagt ttcgtctctc
     2941 tatctagttt tgataactag attatatgat taatgaaaac ttattgcaag caaaaactgt
     3001 aaagacttaa aagaggaaag tagaaatggc gaagtgaagc taatcatgct ataatgttaa
     3061 agaattgatt gggatagatg ccttctgtcg caatcagact attttatcac gaagaagatg
     3121 atgctacgaa aggaatgata cactcatggc aatgattcaa tggtttcctg ggcacatgtc
     3181 caaagccaga agacaggttc aggaaaatgt aaagcatgtt gactttgtaa ctattttagt
     3241 ggatgcacgc ttaccacttt ctagtcaaaa tcccatgctt acaaaaattg ttggtgataa
     3301 acctaaatta atgattttaa ataaagctga cttggccgat gccactcgta cgaaagagtg
     3361 gaaggcttat tatgaaagtc aaggtattaa aacattagcc atcaattcca aagaacaatc
     3421 aacggttaaa aaagtaacag aagcagccaa ggaactcatg gctgataaaa ttcaacgctt
     3481 gcgagagcgc ggcattcaaa aagaaacctt gcgaaccatg attattggca ttccaaatgc
     3541 tggtaaatct accttgatga atcgcttggc tggtaagaaa attgctgtag ttggcaataa
     3601 acctggtgtg actaaaggac aacaatggtt gaagtccaat aaggaattgg aaattctaga
     3661 cactcctggt attttatggc caaaatttga ggacgaattg gtgggcttaa aattagcttt
     3721 aacaggtgct atcaaggacc aattactacc aatggatgaa gtgactatct ttggcttgaa
     3781 ttactttagg gaatactacc ctaatcgttt aaccaaacgt tttaagaata ttcctcttga
     3841 ggaagaagct cctgaaatca ttatgacctt gacacgccaa cttggattta aagacgatta
     3901 tgaccgtttt tacactttat tcgttaagga agttcgtgat ggtaaattag gtcaatacac
     3961 cttagatcag gtgggagata tggatgccga ctagtattaa agctattaaa gaaagcttag
     4021 aggccgttac tagcctcttg gaccccctct ttcaagaatt ggcaaccgac actaggtcag
     4081 gcgtccaaaa agctctaaaa agccgacaaa aggttattca ggccgagtta gcagaagaag
     4141 aacgattaga agccatgctt tcttatgaaa aagctcttta taaaaaaggt tataaagcca
     4201 ttgcaggtat tgatgaggtg ggacgtggtc ccttagcagg tcccgttgtg gcagcttgtg
     4261 tgattttacc taagtattgt aaaattaaag gccttaatga ttctaaaaaa atccctaaag
     4321 ctaagcatga gaccatttat caggcagtga aagaaaaggc tttggctatc ggtatcggta
     4381 ttattgacaa tcagcttatt gatgaggtca atatttatga agcaaccaaa ctggccatgc
     4441 tagaagccat taaacagttg gagggccaac tcacacaacc agattatctc ttgattgatg
     4501 ccatgacatt ggatattgct atttcgcagc agtctattct taaaggcgat gccaattcct
     4561 tgtctattgc agcagcatca attgtagcta aggtcaccag agatcagatg atggctaact
     4621 atgatcgcat ttttcctggt tatggctttg ctaaaaatgc aggctatggc accaaagaac
     4681 atttacaggg attaaaagct tacggcataa cgcctatcca tcgtaaaagt tttgaacctg
     4741 ttaaatccat gtgctgcgat tcaactaatc cttaaaaagt tctgttttta gcagaatttt
     4801 tttctttttt acgaataaat gaagtaagga ggtaacttag tgaatcattt tgaactttat
     4861 aagctaaaga aagctggact gactaataaa aacattctca atattcttga ctaccaaaaa
     4921 caccaggaaa aatcgttgtc acttcgagat atggccgttg tttctggttg taagcatccg
     4981 tctcacttta tagaagccta taagcagtta gatattcaaa atttaaaaat ggaatttaaa
     5041 caatttccta gtatttctat cttagataag cattacccaa tggcattgaa agaaatatac
     5101 aatccacctg tcctcttgtt ttttcaggga aatttagacc ttcttgagaa acctaaatta
     5161 gccattgtcg gctccagacg ctcaagcgat accggagtaa agtctgtccg taaaattctt
     5221 aaagaactcg ggaaccgttt tgtgattgtt agcggacttg ctcgaggtat cgacactagt
     5281 gctcatttag cctgccttaa aaatggggga caaactatcg ctattattgg aacaggattg
     5341 gatcgctttt accctaaaga aaatagggag ttgcaaactt tcttagggaa aaatcatctt
     5401 gtgctaacag aatacggtcc aggagaagaa gctttatctt atcactttcc agaacggaat
     5461 cgtattatcg caggccttag ccgaggtatt cttgtcgttg aagcaaaaaa tcgttcaggt
     5521 tccttgatta cttgtcaaat tgggatagaa gaaggccgag acatttttgc tgtcccagga
     5581 aacattttgg acgggaaatc cgaaggttgc cttcagttaa ttaaagaggg agcaacatgc
     5641 gtcacatcgg gcatggatat cctttcagag tactaaaaaa gttaaagttt cttcctatat
     5701 agcatttttt tattgacagt ttcttaaaaa tgggatatta tgctataagc tttaaacaaa
     5761 ctgttatagg aagtgtgtcg aattgggaac aaaaactaca actaagccaa aaacgggtac
     5821 taaaaagtcc accactaaaa agaaatcaac agcgaaaaaa aatctcgtta ttgttgaatc
     5881 acctgccaaa gctaagacta ttgaaaaata tcttggacgc agttataaag ttgttgcttc
     5941 ggtaggacat attcgtgact taaaaaaatc gtctatgtct attgattttg ataataatta
     6001 tgagccacaa tacattaata tccgtggtaa gggacccctt atcaattctt taaaaaaaga
     6061 agccaaagct gctaaaaaag tttatttagc tagtgacccg gatcgtgagg gagaggctat
     6121 ttcttggcat ttgtcacata tcttaggact tgatcctcaa gataataacc gagtggtttt
     6181 taatgaaatt acgaaagatg cagttaaaca tgcctttgtg gagcctcgtc agattgatat
     6241 ggacttggta gattctcaac aagcacgtcg tgttttggac cgtattgtgg gatattccat
     6301 ttcaccaatt ctttggaaaa aggtcaaaaa aggactttca gcaggacgtg tccagtcggt
     6361 tgctttaaaa ctcatcattg accgtgaaaa tgacatcaaa gcatttgttc caaaggaata
     6421 ctggtctatt gatggtcttt ttaaaaaagg aactaaaaag tttcaagcga ctttttacgg
     6481 tattaatggc aaaaaaacaa agcttgacaa taacaacgat gtcaaagagg tattagcaaa
     6541 gctaacaaat gaagattttc ttgtcagcaa ggttgacaag aaagagcgac gtcgtaatgc
     6601 tcccttacct tacacaacat catctcttca acaagatgct gctaataaaa tcaatttcag
     6661 aacgcgtaaa accatgatgg tagcccaaca actgtatgag gggattcatt taggagaaaa
     6721 tggaactcaa ggtttaatta cctatatgcg tacggattct actcgtatca gtccagtagc
     6781 acaaaacgat gctgctcaat ttattatcaa tcgctttgga gctaattatt caaaacatgg
     6841 taatcgtgtc aaaaatacca gtggtgtcca agatgctcac gaggcgattc gtccatctag
     6901 tgttaatcat acgccagact ctattgccaa ataccttaac aaggatcagt taaaacttta
     6961 tacgcttatt tggaatcgtt ttgtggctag ccaaatgaca gcagctgttt ttgataccgt
     7021 aaaggtgaac ttggagcaaa atggcgtgat ttttgttgcc aatggtagcc aaatgaagtt
     7081 tgatggttac atggctgttt acaatgattc cgataaaaac aaaatgttac ctgagatggc
     7141 agaaggagaa acggttaaaa aaatatcgac ctctccagaa cagcacttta cgcagccacc
     7201 agctcgttat tctgaagcaa ctctaattaa aacgctagaa gaaaatggtg ttggacgtcc
     7261 atcaacttac gctccaacct tagaagtcat tcaacgcaga tactatgtta aattgtctgc
     7321 taagcgcttt gagccaactg agcttgggga aattgtcaac aagcttattg tcgaattttt
     7381 cccagatatt gtcgatgttg cctttactgc cgagatggaa ggtaagctag atcaagttga
     7441 aatcggagaa gaacaatggc aacatgttat cgatcaattc tatcaaccct ttgtcaaaga
     7501 attgaataag gctgagtctg aaattgaaaa gattcaaatc aaagatgaac cagctggctt
     7561 cgactgtgat gtttgtggtc acccaatggt cattaagtta ggacgttttg ggaaatttta
     7621 cgcgtgtagc aacttcccag agtgccgtaa tacaaaagcc atcactaaag aaattggtgt
     7681 tacttgtccg gtttgtcata aaggacaagt tatcgagcgt aaaaccaaaa aaaataggat
     7741 attttatggt tgtgatcagt atccagattg tgagtttatc tcgtgggatt tacctattgg
     7801 acgtgcttgc cctaagtcag gtgactatct tattgagaaa aaagttcgtg gtggcaaaca
     7861 agtaatgtgt agcaatgaga cctgtgatta caaggaagaa aaaattaaat aaaaaaagaa
     7921 ttggaactcc ttgtcttgtt ccaattcttt ttttatttac aaaggtattt ttaactacaa
     7981 aaatcgctag ttcgttttta aaaggcttaa aaattcctca ataactggac tgaaactcgc
     8041 atcatctcgg taagcaatcc caatagggta aaaattattt ttatcttgca aaggaatcca
     8101 aactaagtta tctacctgat taagactctc aaaatcactc gggaggatag tcaaggtatt
     8161 taaatcgtgc aaactatgaa taagaacttc ccaatcattg tgtttaaaga caatatctgg
     8221 ttcaaaaccg agagctcggc attttctagg aagcatttcg cctaacatgt agtgatcgtt
     8281 taaagaagca atcttatagc cttttaaatc tttaagtttt aactgaggat gttgcgccaa
     8341 agggtgctgt ttgaggagaa cgatactgac cttatagcct tttgtggacg tttgtaatag
     8401 ctcaatggta atatcctttc gaatacttag aaaggagagg agaccaatat cgatttttcc
     8461 ttgggacaat aattcttata atttgcgaga accatcctgt ataagcgata attcaacatt
     8521 tgagtgagta gccataaaga ttgaaatttg tttcatgaat tgtatagcaa acagtgatgt
     8581 taattcaaca cgaatcatct ctttttttct tgatttaatt gctgaatatc cgcaacaatt
     8641 tgattaaagt catccacaag gtctttgcct ttgtgataaa atatctccag cttcggttag
     8701 tagtagctgt caatcacttt gtgtaaaaag cgtcgtgttc aaactaggac tctagccttt
     8761 taattgattg agaaagagta ggttgcgtta caaacaaact tttagcagcg tgggaatgat
     8821 tttttgtttc agcaactgca ataaaatagg ttaattgtct aatatccata gtagatcctt
     8881 catgattggt caaggaatag cgtctctact tggtttacaa cctattttga tgtctctcct
     8941 tattgccatg attttctgct tccttattgt ttctccaatt acaacggtag gaattgctct
     9001 tgcgattaac ttatctggta ttggttcagg tgccgcaagc tttggacttt gcttagcagg
     9061 ttgggctgtt aattcaaaag gaacttcact tgctcacgtc ttgagatcac cgaaaatttc
     9121 aatggccaac gttttatcaa aaccaaaaat catgttgcca atgttatgtt ctgcagctgt
     9181 acttggtgtt attggtgcta tctttaatat tcaaggaaca cctgctagtg caggctttgg
     9241 aattagtggt ttgatcggac ctatcaatgc ccttaattta gctaaaggcg gatggtgtcc
     9301 agtaaatatt ctacttatca ttatcatttt tgtaggggca ccaattgttc tcaatatgat
     9361 ctttaactac ctttttatca aggtgcttaa agtgattgat ccaatggatt acaaacttga
     9421 tatctaagaa aggaactttt gatgaaatta aaattatata atgttagagg cgaagaagca
     9481 gtcttagcaa aaaaatgggc tgatgacaat gggattgaga tttccttgac ggagtctccc
     9541 ttaactcctg aaacggttaa agaagctgaa ggctttgacg ggattgccaa tgcccaaatt
     9601 ggtcctttag atgatgcgat ttatcctctc ttaaaggaaa tggggattaa acaaatcgct
     9661 cagcacagtg ctagtgtcga tatgtataac cttgatttgg ccaccgaaaa tgacattatt
     9721 atcacaaatg ttcctagcta ttctccagaa tccattgcag aatttacggt tactattgtc
     9781 cttaatttaa ttcgtcatgt ggagttgatt cgtgaaaatg ttaaaaaaca aaatttcact
     9841 tggggactcc ctatccgcgg ccgtgtttta ggtgatatga cagttgcgat tatcggaact
     9901 ggacgtattg gtctagctac tgctaaaatc tttaaaggtt ttggctgcaa ggtcgttgga
     9961 tatgatattt accaaagcga tgctgccaaa gctgtcttgg actataagga atctgtagaa
    10021 gaagcgatta aagatgctga tcttgtttcc ttacacatgc caccaactgc agagaacaca
    10081 caccttttca attctgattt atttaaatca ttcaaaaaag gggctatttt gatgaatatg
    10141 gcgcgtggtg ccgtcattga gacgcaagat ttactggatg ctttggatgc aggcttactg
    10201 agcggagctg gtattgacac ttacgaattt gaaggacctt atatacctaa gaattttgaa
    10261 ggtcaagaaa ttacagattc actatttaaa gctttgatta accatcctaa ggttatttat
    10321 acacctcatg cagcttatta tactgatgaa gccgttaaaa acctagttga aggtgccctt
    10381 aatgctacag tagagattat caaaactggg acaacgacaa ctcgtgttaa ctaacaactg
    10441 atttgacgtc cattataaag gaataattct aaaaattcct ttataatgga cttttttgta
    10501 ttagtccgtt ataatagact gtaagaaagg ggactcttat gacatatata gcgcttattg
    10561 gagatattat ccagtccaaa caattgacgg atcgttccaa agttcaaaaa actttagcag
    10621 cttatttaga cgacctcaac aaaacctttg ctccttatat tatttctaaa ttatccctaa
    10681 cgttgggaga tgaatttcaa ggactttttc aggtggatac tcctattttc catctgattg
    10741 atttgattaa tcatcacatg gatatcccta ttcgatttgg agtaggagta ggttctattc
    10801 taacagacat caatcctgat attagtattg gggctgatgg acctgcttat tggcatgctc
    10861 gtgaggctat tcgttatatt catcaaaaaa atgattatgg taatactaca ttagctcttc
    10921 ggactggtca tcacaaccag gatgatgtat taaacagttt actagcagct ggagatgcta
    10981 ttaaagccaa ctggcgagct agtcaatggg aaatttttga cacgctttta gatttgggca
    11041 tttatgagga atactttgat caacaacgac taggaaagca attatctctt agctctagcg
    11101 ctttgtcaaa acgtctaaaa agtagtcatg ttaaaattta tctgagaaca cggcagagtg
    11161 cgctaaactg tctcaaacaa atcaaggagg aaactgatga ttaatggtgt ctctcactac
    11221 ctagctcaaa cccctacact taccctgttt ctcatttgtc atgtgttatc agactaccag
    11281 ttacaaagtc agcaagtagc tgatttaaaa gaaaaacatt tgacttattt aggttaccac
    11341 ttgattggag ttagcattcc cctaatttgt ttaaccctca ttatcccaca agcatggttg
    11401 atgagcctat tggttatgat aagtcacgcg cttattgact ggctaaagcc aaagatggct
    11461 aactctctaa aatggaaaag agagtggatt tttctgctgg atcaatgctt acatatcgct
    11521 attagttcat ttgctgggct aaggttagca ggggtgacct tgcctaattg gcttccgata
    11581 tctattttga tgaccgtttt atttatccta ctcattacca aaccaactaa tattgtcttt
    11641 aaactctttt tcagcaaata ccagcctgac caaggagaaa aaatggacac gatcatagga
    11701 gcgggggcta ccataggaat tctagagaga attgttattg gggtgtgtat gatcatgggg
    11761 caatttgctt caataggtct ggtctttacc gctaaatcta ttgctcgcta taataaaatt
    11821 tcggaaagtc cagcttttgc agaatactac ctaattggtt ctttatttag tattctcagt
    11881 gtttttatcg cagcatggat ttgtttcttc tagttgaaaa gggttcccgt agaaagagac
    11941 taacgcttag tctctttctt tttctttctt cttatttctg ttataataag tcaggtaact
    12001 acattagaaa gatttgtggg tctgtcatct aagagatgtc attcccgaag aggtattagt
    12061 gacttgtctc aatcaactgc aacttatatt aatgttattg gagctgggct agctggttct
    12121 gaagctgcct atcagattgc taagcgcggt atccccgtta aattgtatga aatgcgtggt
    12181 gtcaaagcaa caccgcaaca taaaaccact aattttgccg aattggtctg ttccaactca
    12241 tttcgtggtg atagcttaac caatgcagtc ggtcttctca aagaagaaat gcggcgatta
    12301 gactccatta ttatgcgtaa tggtgaagct aaccgcgtac ctgctggggg agcaatggct
    12361 gttgaccgtg aggggtatgc agagagtgtc actgcagagt tggaaaatca tcctctcatt
    12421 gaggtcattc gtggtgaaat tacagaaatc cctgacgatg ctatcacggt tatcgcgacg
    12481 ggaccgctga cttcggatgc cctggcagaa aaaattcacg cgctaaatgg tggcgacgga
    12541 ttctattttt acgatgcagc agcgcctatc attgataaat ctaccattga tatgagcaag
    12601 gtttacctta aatctcgcta cgataaaggc gaagctgctt acctcaactg ccctatgacc
    12661 aaagaagaat tcatggcttt ccatgaagct ctgacaaccg cagaagaagc cccgctgaat
    12721 gcctttgaaa aagaaaagta ttttgaaggc tgtatgccga ttgaagttat ggctaaacgt
    12781 ggcattaaaa ccatgcttta tggacctatg aaacccgttg gattggaata tccagatgac
    12841 tatacaggtc ctcgcgatgg agaatttaaa acgccatatg ccgtcgtgca attgcgtcaa
    12901 gataatgcag ctggaagcct ttataatatc gttggtttcc aaacccatct caaatggggt
    12961 gagcaaaaac gcgttttcca aatgattcca gggcttgaaa atgctgagtt tgtccgctac
    13021 ggcgtcatgc atcgcaattc ctatatggat tcaccaaatc ttttaaccga aaccttccaa
    13081 tctcggagca atccaaacct tttctttgca ggtcagatga ctggagttga aggttatgtc
    13141 gaatcagctg cttcaggttt agtagcagga atcaatgctg ctcgtttgtt caaaagagaa
    13201 gaagcactta tttttcctca gacaacagct attgggagtt tgcctcatta tgtgactcat
    13261 gccgacagta agcatttcca accaatgaac gtcaactttg gcatcatcaa agagttagaa
    13321 ggcccacgca ttcgtgacaa aaaagaacgt tatgaagcta ttgctagtcg tgctttggca
    13381 gatttagaca cctgcttagc gtcgctttaa cactaaaaaa gagttccttt tcagttgagt
    13441 tgctgaagag gactttttta cttgctgatt tgagcgctag ctatgcaaaa gaatgcacaa
    13501 aaaatacatg aatagactat ggtcactaga agcaatatta tataatgaat agtactcatt
    13561 agttgattca gtttggaggt tttagcatgc agcagcaagt cgcaataaca gaaacagttt
    13621 tacgggacgg tcatcaaagt ttgatggcaa cgcgtttatc tattgaagat atgcttcctg
    13681 tccttaccat cttagacaag attggttatt attccctaga gtgttgggga ggagcaacct
    13741 ttgatgcctg tattcgtttt ttgaacgaag acccttggga aaggctgcgc acgttaaaaa
    13801 aaggcttacc taatacccgt ttacaaatgt tattaagagg ccaaaacctt ttaggctacc
    13861 gtcattatgc agatgacatc gttgacaaat tcattagttt atcagctcaa aatgggattg
    13921 atgttttccg catttttgat gccctaaatg acccacgaaa tatccagcaa gccttaagag
    13981 ctgtgaaaaa gacgggtaaa gaggctcaac tgtgtattgc ctatacaact agcccagtgc
    14041 acacgcttaa ctattacctt tctttagtga aagaattggt tgagatggga gctgattcta
    14101 tctgcatcaa agatatggct ggtattctaa ctcccaaagc ggctaaagag ttggtatctg
    14161 gtatcaaagc catgactaac ttacctctta ttgtgcatac ccatgcaact agtggcattt
    14221 ctcagatgac ctatctagca gcagtagaag ctggtgctga tagaattgat acggctttgt
    14281 caccttttag cgaaggcact tcacaacctg ctacagaatc catgtattta gccttaaaag
    14341 aagcaagtta tgatatcaca ttagatgaaa cgctactgga acaggctgct aatcaccttc
    14401 gacaagcccg tcaaaagtac ttagcagatg gcattctgga tcccagtctt ctctttccag
    14461 acccaaggac actacaatac caagttcctg gaggcatgtt gtctaatatg ctatctcagc
    14521 tgaaacaagc caatgccgaa tcaaaattag aagaagtttt agcagaagtt cctcgggtaa
    14581 gaaaagactt gggttatcct cccttagtaa caccgcttag ccaaatggtc gggactcaag
    14641 ctgctatgaa tgtgatttta ggaaaacctt accagatggt gtctaaggaa attaaacaat
    14701 acttggcagg cgactatggc aaaacaccag caccagtcaa cgaagactta aaacgaagtc
    14761 aaattggctc agctcctgtc accacaaatc gtcctgcaga tcaactaagt cctgaattcg
    14821 aggtgttaaa agcagaagta gcagatttag cccaaacgga cgaagatgtg ctgacttatg
    14881 ccctcttccc aagcgtagca aaaccgtttt taacaaccaa ataccaaact gatgacgtca
    14941 ttaaagtgac tgcctttatc aaagcataat aggctatctt aatcagatag aaacaaaaat
    15001 atggagatca aatgacctat tcctttattg atatcttaca agttacctta gtatccttgt
    15061 tcttagtgtt aacctgttta acagggatta tgggattaat gatgctaagt ggtaaattat
    15121 tgtcacaaga aaaaaaaact ctctctcaac aagcttccag cattcctcaa gagcaagaag
    15181 ctgacaagtt gagtggagaa gctctcgaaa ctcttttagc caaagacgaa ttggctagaa
    15241 ttgctgttat gactagtctt gcttatgcta gccaagaaga gtcaggaaaa cggtttgaag
    15301 ttattgccgt ggaaaggaaa tcctaatgaa aagatatgaa gtgactgtca atggacaggt
    15361 ttatgaagtg agtttacgtg aactagttga tggagaaact gttgaagtta gccagccagc
    15421 agcacccgct actgagaaag aaatgaatgc caacgctgct ggcggtggca ttcaggtaaa
    15481 ggctccaatg tctggaacag tcttgtctat ctttgctaca gaaggaaaag ctgttaaaaa
    15541 aggagaagct gttctggtct tagaggccat gaaaatggag aatgaaattc tagcacctgc
    15601 agatggtctg gtttcaaaaa ttcatgttgt ggctaaccaa acggtcgagt ctgaacaagt
    15661 tttgatttca ttctaggagg aaaccatgct agacgtactc aatcaaatgg tccaatcgtc
    15721 aggattggct catctaactg ttaataatct tatcatgatt tgcttggcca gtttcttttt
    15781 ataccttggt atcaaaaagg aatatgagcc ttaccttatg gtaccaatcg cctttgggat
    15841 tttactcgtt aatttgccta tggcgggatt gatggaccac cctgccaatg gtaatcctgg
    15901 tggccttctt tattacctat ataagggaac tagcctaggg atttacccac ctttaatttt
    15961 tctttgtttg ggggcatcaa ctgactttgg tcccttgatt gccaatccta aaaccatttt
    16021 actaggaggc gcagcacaag ttgggatttt cttagccttt ttccttgcta ttatgttagg
    16081 catgacacct caagaagcgg cttctgtcgg gattattggt ggtgccgatg gaccaacagc
    16141 tatttatgtg acgacaaagt tggcgcctga tttactctct actatcgccc tagcagctta
    16201 ttcttacatg gctctggtac ctattattca acctcccatc attaaactct tgactaccaa
    16261 ggcggaacgc caagtgaaaa tgactcaagc aagaactgtt tcacaaaaag aaaaaatcat
    16321 tttcccgatt atggtaacaa tctttgtcag ccttttggtt ccaagtgcta caaccttggt
    16381 tggctgtttg atgctgggaa atctggtcag agaaattaaa attgttccta aaattgtaga
    16441 gaatctccaa caagtggtta tgttttgcat tactatcatt ttagggttaa ccgttggtgc
    16501 taaggccaat ggagatctct ttttatcagc cacaaccttg aaaattattg cccttggact
    16561 aatcgccttt gctgctggga cagcaggggg tgtcttgatg gggaaggtca tgtactattt
    16621 atctggtaac aaagtgaacc ctatgatagg agcagcaggt gtttcagctg ttccgatggc
    16681 agcacgagtg gtccaaaaga tcggacaaga agaagatcca agtaatttct tactcatgca
    16741 cgccatgggg cccaatgtag ctggcgttat tggctcagcc attgcctcag gtgccttgct
    16801 ggccttcttt ggctaattgt gaaaaaggat tagtaaatta atcttaataa atcattatca
    16861 ggagttggaa gcaatctagc tcctttttta gtagaaagct cgagtgataa actattccaa
    16921 aataattata aaaaagactg tcctgattgt acggactata tcagttgact tttatagtct
    16981 agctgaaata gcagtgcaaa actaagacac tcgttttaaa gtagtttttc taaaaaagca
    17041 aaataaaagg tcagagccaa taaatctgcc gcgcccccag ggcttaaatg ctgattaatg
    17101 aggcattgat tgtaggagga caaagccaat cttaggtcag ttgttgataa atcttgttgc
    17161 aggagtagtc gcatatctgc cttaacgcct ttccatgctt caatccctcc acgatgaatc
    17221 agatttccat cttcaacaat agacatcaaa taaacaagaa gacgaagctg actggtttcg
    17281 gggtcatttt gacttatcat ctgacgaaag tagggcaagg catggtctgt taaggtcgtg
    17341 aatccctcgc ttgcctcacc ccgaggtcct ttgatgccat aagttacaaa gagttgctcc
    17401 ccataagtga actctttttt agtgttcaaa tgaccaaggt ctgtttgaat caaatgtgcc
    17461 gtcataggtt ttactaaacg acagatagct agagtatctt ccttgctaaa acgccctaaa
    17521 tcagtcatta agtgaggtgt tcttgctaga taggccccag ttgcaccaag aagtaaagcc
    17581 atggaaaaat tcaggccttt atgagtgtta attccctgag tagcacaaaa catggtttcc
    17641 tcggcctttt gacctagttg tctaagacgg ttaaacagaa gaagtggctc ttcttttgca
    17701 taagcaaaac ctgtttcgat ataagcctga aaaaaaggag agagtgctat catactgtcg
    17761 ataaaggtta taaaggacat gtcatcatgg gcaccgttat caaatcgatc aactaaacca
    17821 ggttttggag atagtgagac ttcataaagc aaagctttta aggccagttg actaatactt
    17881 gttagaactg ccttagtcat tttgctcagg cctcatttct tttaagataa attcaagtga
    17941 gctattcaag tgttcatgtg taatcaacgt aatttgctca tgatctttgt tcttcatacc
    18001 tcggtaaatc atccagtgtt cagatagagc tcgtttacgg cgttcaactg aagaaatcga
    18061 aatttttcta aagtagacca aataagcttg caattctgtc acaatttctt ttaagcggac
    18121 catttggcta tagctgtaaa tcaaattgtt aaaggcatta aaattatcca aaatacgatt
    18181 ggtgtcatcc tctgcgataa aggtttcaca gtcttccaac aagttatgca tgactttaaa
    18241 atcttcttct gtcattaaat gcatcgcttg cactgttgcg agagtctcta gagcttttcg
    18301 aatttcaaaa atttcacagg catccttgat actaactcct ttgacaataa tgcctttttt
    18361 aggaatgtgc tctacaaggt gttcttcaga caataatccc aaagcgtagc gaataggtgt
    18421 cctgctaata ttaagcgcaa tggaaaactc tttttcatta atgcggcttc caacaggaat
    18481 ttgtcgcaaa ataatggtct ttttaagagc gttataaaag gctattttca aagggatatt
    18541 tcttgatagg tcaagatttt gtttaacggc ttcgataata ggattcatgt catctcctta
    18601 atgctagtgt cctcacttta ttatacttaa atttgtgaaa cattccaata ggactagatg
    18661 agttctgaaa aattaaagcc atgctcacaa aaggacatga ctttaatcat ctcataagga
    18721 ataaggtagt agtgttatcg ttggtttatt gtggaatgta aagtggcatt tgtcccatgg
    18781 caataatggt taccacaaag ataacaaaga tgataagggc atatttagca gcctcttttt
    18841 gccattcccc catgtcaaga cctgtcaagc gaagaagaag ataaatgaag gcaactaatg
    18901 gactaagtaa gtggaaggct tgtcccatga gggaagcaag tgccatagcc atgttactga
    18961 aaccatattc agcaccagct tctgcaagaa caggcaagat accatagtaa aaaccatcat
    19021 tggagataaa gaaggtacca ggtgcagaaa ctaaggcaat aacgagaccc cagaaacctg
    19081 ccagttgttt tggaataatg gttgcaaaac tttgtgcaag agcgctagcc ataccagaac
    19141 cttgaaaaag acccataaag ataccagcag caaagacgag aataaccact tgaaccgcat
    19201 caccagcatt gtcaccaatg cgttttgatt gatctttaag cactgggtaa ttgaccatca
    19261 aggcgataca agttcccacc gcaaaaagaa gaagcggtgc catagcaata gatttgttga
    19321 aagagccagc aactaaccaa gtgattaatc caatggttaa gatagcattg aaaacaaagt
    19381 ttttaggacg acgaataaaa agggtatctg ggtcagtaat gtctgtgagt tgacgcatgt
    19441 cttcttcaga caagtcaata acaccaagtc ttgcacgttc tttacgcccc atgcttggag
    19501 caacccaaca aatcacataa agaagagata aaatcatacc cggtgcaaga tagccaagaa
    19561 tttcaggacc gacaccaaga acagacatcg cacgagcagt agggccaccc catggcagta
    19621 agttcataat agtattttga agaataatca agacacctag gttcatgatt ttcatgtcca
    19681 attttttata gataggtaag aaagcagagc aacaaattaa agtagtggtt gttccatcac
    19741 cattaagaga tactgcagca gcaacgacag ctgttgcgat aagcaccttc attggatcac
    19801 ctttagcaaa gcgaatcatc ttttcagtaa tcggatcaaa caatcctgca tctaacatga
    19861 cagagaagaa caaaatggca aatagcaaca tgatacctgt tttagcagta ttgttgatac
    19921 catacataac cattggtccg atagctgtta ggtctttagc aattccaccg tcaccaacaa
    19981 aggcaacaaa tttggcatct gcattgaagt cagctgaacc agtcagtata acagcaatcg
    20041 tcatgattaa tggaatcatg accaaagcag taaaaggggt catttttttc ttcattacca
    20101 cgtacataaa gacaataatc atggcataag ccagcattgt taataacatc attgttatct
    20161 cctttttcaa gttatgattt cagtatagat gaaagcgctt ataaaataaa tacttctttg
    20221 tgcagaaaga cacaaaaaaa acaatttgaa aattaatttt gaaaaccatt tttattacat
    20281 caggtgactt taaattttct ataataatga tgaacctagt tagatcaagc ttttcttgct
    20341 atcagtatct tgatctcagt ttttcaacag ttacctaaaa ataaaataaa aggtaactgt
    20401 tgaaaaactt tatgaaacat tgaaagcgct cttagaaaga acacaaaaaa gccatctcaa
    20461 aaaagattgg tagtatataa taaacttact agttccttaa ataggtaaat gtgaaaaaga
    20521 ggtagctcat gcagttttta caaaaatggt ttaaacactc taaaaaagag aagttgaaag
    20581 aatcctcgtc ccttagtaca gaaatagaac cttctgaaaa ctgggcaaag attcccgctt
    20641 atattcctgc agacaaaagt gattacaaaa aggttacttt aattaccagt gttattgctg
    20701 ctggcgatag acctaatagt caattcaagg ttaaacgcat tctcaagcgc aatcctgagg
    20761 caatcactgt ttctttaatt gcttcaagta tcgctgcagg tgtttaccca gaaagtcagt
    20821 ttcgggtgac atccatctat tgcaaaaggt agtcggtgaa cgatacttta gacgaactca
    20881 tgacacaata acatatagga gaaaaatgat gttacgaaaa tttaaaatta ccattgacgg
    20941 taaagagtat cttgtagaaa tggaagaaat cggtgctcct gcccaagcag ctgcccccgc
    21001 tcaaccaata tccactccag tacctgtccc tactgaagca agcccacaag tggaggaagc
    21061 gcaagcacca cagccagtag ctgcagcggg agcggatgcc attccatcac caatgcctgg
    21121 aaccatctta aaagtcttag tagcagtggg agaccaagta actgaaaatc agccactatt
    21181 gattttagaa gccatgaaga tggaaaatga gattgtggcc tcatcagcag gaaccattac
    21241 agctatccac gtcggtccag gtcaagtggt caatcctggt gatggtctca ttacaattgg
    21301 ttaatagtac tataactaga ataaatagac agaaaaggaa gtgaatttgt ggacacttta
    21361 atcgcaggaa taacctccat caccattcct caaattgtta tgatggtcat tggtgccctc
    21421 ttaatgtatc taggaattaa aaaagaatac gaaccaacct tacttgtccc catgggactt
    21481 ggaaccattc tcgttaactt ccctggttca ggagttttaa cacaagtggt taacggagtc
    21541 gagcaagaag gggtttttga ggctctcttc aattttggga ttggaacaga acttttccca
    21601 ctgttgattt tcattggtat aggagccatg attgactttg gccccttgct tcaaaaccca
    21661 ttcatgctct tgtttggtgc tgcagctcaa ttcggaattt tctttgttgt ggttgttgcc
    21721 gtactggctg gctttgacat taaagaagca gcttcaatcg gcattatcgg agcagcagac
    21781 ggaccgactt ctatctttgt tgccaaccaa ctggccaagg atttactggg tccaattacg
    21841 gttgcagcct attcttacat ggctctggtt cctattatcc aaccatttgc cattaaatta
    21901 gtgacaacga aaaaagagcg ccgtatccgt atgacttaca aagctgagaa tgtatctcaa
    21961 atgactaaaa tcttattccc aatcatcatt accttagtag cagggttcat cgccccaatt
    22021 tctctacctt tagttggctt tttgatgttc ggtaacttat tacgggagtg tggtgtgctc
    22081 gatcgcctgt cacaaactgc tcaaaatgaa ttggtaaaca ttattagtat cttgcttgga
    22141 ttgaccatct ctattaaaat gcaggcagac ctgttcttaa atgtacagac actcttaatc
    22201 atcgtctttg gtttacttgc ttttatcatg gattctatcg gtggggtcat gtttgccaaa
    22261 tttctcaatc tcttccgaaa agagaagatt aatccaatga ttggcgctgc gggtatttca
    22321 gcttttccaa tgtcaagtcg tgtcattcaa aaaatggcaa cagatgaaga cccgcaaaac
    22381 tttatcctca tgtatgctgt aggtgccaat gtctctggcc aaatcgcctc tgttatcgca
    22441 ggtggtttgt tgctagctta ctttagctaa gaaaggaagg aaaccttatg acaattaata
    22501 tggaccattt gattagttcc tttgagctaa tggcgcttgg tatggcaggt gtctttatcg
    22561 tgttaggcat tctctatctt gtcgcagaga tcctgatcaa acttttccca gttagtaaat
    22621 aacaatatca tttaagaaaa tcaaggaggt aaacgcaatg gatattaaac aaactgccgt
    22681 tgctggttca cttgaatcaa gtgacctaat gattacagta tcccctaatg acgagcaaac
    22741 cattacaata accctagaca gtagtgttga aaaacaattt ggcaatcaca ttcgtcaact
    22801 cattcatcaa accctagtga atttgaaggt gacggctgct aaagtagagg ctgttgataa
    22861 aggtgcatta gattgcacca ttcaagcgag aaccatcgca gctgttcatc gcgctgctgg
    22921 tattgaccaa tacgattgga aggagattga ctcatggaac gtttaagaag aacaatgatg
    22981 tttgtgcctg gtgccaatgc agccatgctt cgagatgctc ctttatttgg cgctgattca
    23041 atcatgtttg acttggaaga ttctgtttca ctcaaagaaa aagacacctc tagagctctc
    23101 gttcattttg cgcttaaaac ttttgattat tcaagcgttg aaacggttgt tcgtgtgaat
    23161 ggtcttgatt cttgtggggc tttagacatc gaagctgttg ttttggcagg tgtcaacgtg
    23221 attcgtcttc caaaaacaga gactgctcaa gatattattg atgtggaggc tgttattgaa
    23281 cgtgtcgaac gcgagaacag cattgaagtt ggtcgcacac gtatgatggc agccattgaa
    23341 tcagccgaag gtgtcctaaa tgctcgtgag attgccaaag cttctaagcg cttgattggt
    23401 attgctcttg gagcagaaga ctatgtcacg aatatgaaaa cgcgtcgtta cccagatggt
    23461 caagaattat tctttgctcg tagcatgatt ttacacgctg ctcgtgctgc tggaattgct
    23521 gccattgata ctgtttattc tgatgtcaat aataccgaag ggttccaaaa cgaagttcgc
    23581 atgatcaaac agttaggatt tgatggtaaa tcggtcatca accctcgcca aattcctctg
    23641 gtcaatgaga tttatacccc aacaaaaaaa gaaattgacc atgccaaaca agtcatctgg
    23701 gcaattcgtg aagctgaaag caaaggctct ggcgttattt ccttaaatgg aaaaatggtt
    23761 gataaaccaa tcgttgaacg tgcagaacgt gtgattgccc tagcaacagc agcaggtgtt
    23821 ttatctgagg aggatattta aagatggtaa caaataaact cggtagagat attcctcaac
    23881 catacgccga ccaatacggt gtctttgaag gagaactcgc aaatatcaaa cagtatgacg
    23941 aatcaagtcg ccgtattaaa ccagttaagc ctggagattc taaattacta ggatctgttc
    24001 gtgaagcgat tgaaaaaaca ggtttaacag atggcatgac catttctttc caccaccatt
    24061 tccgtgaagg ggatttcatt atgaatatgg tcttggagga aattgccaaa atgggcatta
    24121 aaaacctgtc tattgcccca agttccatcg ctaatgtaca tgagcctttg attgatcaca
    24181 tcaaaaatgg tgtggtcact aacatcactt catctggtct tcgtgacaaa gtaggggcag
    24241 ccatctcaga aggactaatg gaaaatcctg tggttattcg ctcccatggt ggtcgcgctc
    24301 gtgccattgc tagtggggat atccatattg atgttgcctt tctgggcgcc ccaagttcag
    24361 atgcttacgg aaatgttaat gggacaaaag ggaaagcaac ctgtggttct ttgggctatg
    24421 ccatgattga tgccaaatat gcggatcagg tggttatctt gacagataat ttggttcctt
    24481 atcctaatac cccaatcagc attcctcaaa cagatgttga ctatgtggta acagtggatg
    24541 ctatcggaga tcctcaagga atcgccaaag gggcaactcg ttttacgaaa aatcctaaag
    24601 aactcttaat tgcagaatac gccgctaaag taatcaccaa ctctccttat tttaaagaag
    24661 gattctcttt ccaaactgga acaggtggcg cttctttggc agtaacccgt ttcatgcgtg
    24721 aagctatgat taaagaaaat atcaaagcta gctttgctct tggtggtatt accaatgcta
    24781 tggtggagtt gctcgaagaa gaactggttg aaaaaattct tgatgtccaa gactttgatc
    24841 acccatcagc tgtttctctt ggtaagcatg ctgaacatta tgaaattgat gccaacatgt
    24901 atgcctcacc tttgagcaag ggtgctgtta tcaatcaatt agacacttgt attttatcag
    24961 cccttgaagt tgatactaac ttcaatgtta atgtgatgac aggatctgac ggcgtgattc
    25021 gtggcgcttc tggaggacac tgcgacactg cctttgcggc taagatgagt ttggttattt
    25081 caccacttat ccgcggacgc atcccaactt ttgtagatga ggttaatacg gtcattacac
    25141 caggaacaag tgtcgatgtg atcgtcacag aagtgggaat tgccattaac ccaaatcgtc
    25201 aagacttagt agaccatttc aaatccctca atgtgccaca atttagtatt gaggagctaa
    25261 aagagaaggc ttacgccatc gttggcacac ctgagcgtat tcaatatggt gataaggttg
    25321 ttgctcttat tgaataccgt gacggtagcc tcatggatgt ggtttacaat gtgtaaagac
    25381 acttattttt caggcgaagc tatccaactt agtgatatgt taagagcccg cgaagaaaga
    25441 gctctgcgtc agctgcattt attaaaggag tacccagaag gtagcttatt atcggtcacc
    25501 atgaatatcc ctggaccaat taaaacctct cctaaacttc ttgaagcttt tgatatagtg
    25561 attaaggcca ttcaaactgc cttagctgac gataagattt gttaccagtt gcgattactg
    25621 cctacaacgg gttatgagta ttacctcatc acaagtctac ctagccgcga cctgaagtta
    25681 aaaatgatag ccttagagac agagttgcca ataggtcgtc tcatggattt agatgtcttg
    25741 gtcttgcaaa atgatctgcc tcattcaatt agcagaaccg tattaggagg ctcccctagg
    25801 caatgtttta tctgttctaa agaggccaaa gtctgcggtc gcctacgtaa gcacagtgtc
    25861 gaggagatgc agactgctat ttcaaaatta ctccattcat ttttcaataa agacaaccaa
    25921 tcatcgtcat cagataagac aggttgatga ggagaacaat tatgacgaaa atccgtataa
    25981 cggaaacagt tttacgtgat ggtcaacaaa gtcagattgc cacacgtatg acaaccaagg
    26041 aaatgattcc tattctcgaa acgctagaca atgctggtta tcatgccctt gaaatgtggg
    26101 gaggagcaac ctttgattcc tgcctacgct ttttaaatga agacccttgg gaacggctaa
    26161 gagccatccg taaagcagtg aaaaagacta aacttcagat gctcttacgc ggacaaaacc
    26221 ttcttggata tcgcaattat gctgacgatg tggtcagatc ctttattcaa aaatccattg
    26281 aaaatgggat tgatattgtc cgtattttcg atgctttaaa cgacccacgc aacttgcaaa
    26341 cagctgtttc agcgactaaa aaatttggag ggcatgctca agttgccatt tcttacacga
    26401 caagtccggt acataccatt gactactttg ttgaattggc gaaagcttac caagctatcg
    26461 gagcggactc catttgtatc aaagacatgg ctggtgtctt aactcctgaa ataggttacc
    26521 aattggtcaa atgtatcaag gagaatacaa ctatccctct tgaggttcat acccatgcta
    26581 ccagtggtat ttcagaaatg acttacttaa aagtagcaga agcaggagct gatattattg
    26641 atacggcgat ttcctctttt tcagggggaa ccagtcagcc tgccacagag tcaatggcga
    26701 ttgccttgac ggatttaggc tttgacacag gcttggatat gcaagaggtg gccaaagttg
    26761 cagaatattt caacactatt cgtgaccact atcgagaaat agggatttta aatcctaaag
    26821 tcaaagatac tgagccaaaa acattgattt accaagttcc aggtggcatg ctatcaaacc
    26881 tattgagcca attaaccgag caaggcctaa ctgataaata cgaagaagtc ttagcagaag
    26941 tacctaaagt aagggctgat cttgggtatc cgccactcgt aacgccatta tcacaaatgg
    27001 ttggcacaca ggccttgatg aatatcatct caggggaacg ttacaaggta gttccaaatg
    27061 aaatcaaaga ctatgttcga gggctatacg gtcaatcacc agcgccatta gcagaaggta
    27121 tcaaagagaa aatcattggt gacgaagcag ttattacttg cagaccagcc gacctaatcg
    27181 agcctcaaat gatttatcta cgtgacgaga ttgctccata cgctcattca gaagaagacg
    27241 tgttaagcta tgcaagcttc ccgcaacaag ctagagattt cttgggacgc cgtgaagatc
    27301 ctttctatga tgttccggtt caagaagtta ctgtacaact ggacattcaa gactaacaga
    27361 gaatgactaa tcctcttaac cattaatctc cttggtgaaa cgcatttgct gtaagaacaa
    27421 taccaaaaac ctacctgatt ttgataatca gataggtttt ttatcttagt aatgtttgac
    27481 agatgaagtg gcttgtatct ttttaataat gggttgggct tctagcgaac aaaaataatc
    27541 taaagacgtt ttgggaagga gttttgccag aaggtcccaa tcattatctt tcaatgcctg
    27601 cctagccgtt gaggcactga taggatcttg ctgctgattg atagctttcc ttggcaaaat
    27661 atctaggagg ataccagctt gctgcaactg ctctgccata atttcattgt aaatagcagt
    27721 tactcggctg gttggctctt ctccaacgta tctttttgta atctgtaagg tttgagcaat
    27781 ctttagaaaa atagcagtat ccagcaaagc ttggctctta atcacgtcat tgtcttcttt
    27841 ttggaaatag gctgggaaag tcgcttggct aatcaaataa ggacctgttt catgatatat
    27901 gacattatca agatgagcta gaccttcttg aatcaacctc tttctcaccg aaaaaggaat
    27961 tagactgcgg tcttcactga ccataaacag atgaacccaa tcattttctc ttgcagcttt
    28021 ctctactaaa aattgatgcc ctaaggtaaa ggggttagcg ttgataacaa tagcagcgac
    28081 tttaccaggt gtttgctcag gcttattaag tgtcatcaga taatcttgaa aaccagtttt
    28141 tttattttcc aagaaactga tgtgattgtc gatatggaca atttcagtaa aaccaagatc
    28201 tttgaaaaaa gcagcagaag aggtcttcgt ataaacaaaa agatgatagt tgccaagggc
    28261 atattcttca tcaatgagat gactcacaat cctattaaga agtccttcac cttgataggc
    28321 actggatacg caaagacagc gcaagctatt tccaaagtaa gaaccggtag caatcacatc
    28381 attttgcgca ttcatgatgg cacaagtata atctaaatga gcatccaaac gaataccttc
    28441 ttgatgaagc aggttcttta cactagccat tgtcgtttta tctgaaggaa agacttttga
    28501 aatagtgtag taaggcattt cttctcctta tctttaattt tattgaatca taacataact
    28561 tagtaccaaa acaggctgat ctatctaaag gcaactctgt tttttatcaa cgccattttt
    28621 taaaaggaaa tcgaatgtgt ttgacagact caaaagtatc agcgattttt tgattgcgtt
    28681 ccacagtccg caagttttct tggtctaata agtcttgact tttttccaaa acatcaacag
    28741 taatgtagta gagtttgatc aggcttccta tcttatattt accagatttt ggagacatag
    28801 caaccacttc attgagatta ctatgaagcc attttttatg aggcttagca ggtatagtgg
    28861 ctactacaaa gccaagttgt tccaaatgag cttgtgcctg atcaacagga agattaatca
    28921 catcatttat cgtgcgtaat tgcatctctt tttcatgttt ttgttccata cgtttttcga
    28981 taattggtcg actgttatca atcgtttttc caataatttc agtagtgtca ggaacaattg
    29041 acatcagttt cccaactact cctagagctt ttcttattct ctttggcatc ttttatctcc
    29101 tcaagtcgtt tctttttatt ataacaaaat gtctaaaaat agtatgcgat aaaccttgtt
    29161 ctaaaaggtt aaatagatca attcaaggaa aaaataggag gggatccgac aaaaaaacac
    29221 aaagattcta aaaaagtcaa gctattttag tttagccttt gtcaatcgta tcagttcaaa
    29281 tagaaaatac aagttttgac aagaatttat ttatgtaaca aactgtgttt ttgattcttt
    29341 agtctatcta acgataatgt tatctgattc ttgttttcaa ccaattgatg ttaaagaagc
    29401 tgtcttcatg attctctaat attccttcaa ttttagcttt atattactct aagtta
//
LOCUS       DAUGQX010000023        28710 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUGQX010000023 DAUGQX010000000
VERSION     DAUGQX010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28710
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.023"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            266..1672
                     /locus_tag="VIA51_000965"
     CDS             266..1672
                     /locus_tag="VIA51_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEQ8682912.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LEPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNCFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
     gene            complement(1740..2650)
                     /locus_tag="VIA51_000966"
                     /pseudo
     CDS             complement(1740..2650)
                     /locus_tag="VIA51_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            2771..3955
                     /locus_tag="VIA51_000967"
     CDS             2771..3955
                     /locus_tag="VIA51_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8682913.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            3967..4626
                     /locus_tag="VIA51_000968"
     CDS             3967..4626
                     /locus_tag="VIA51_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8682914.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANQA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            4629..5276
                     /locus_tag="VIA51_000969"
     CDS             4629..5276
                     /locus_tag="VIA51_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8682915.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(5398..6078)
                     /locus_tag="VIA51_000970"
     CDS             complement(5398..6078)
                     /locus_tag="VIA51_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8682916.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            6252..6617
                     /locus_tag="VIA51_000971"
     CDS             6252..6617
                     /locus_tag="VIA51_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8682917.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            6654..7673
                     /locus_tag="VIA51_000972"
     CDS             6654..7673
                     /locus_tag="VIA51_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEQ8682918.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            8128..8448
                     /locus_tag="VIA51_000973"
     CDS             8128..8448
                     /locus_tag="VIA51_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682919.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            8438..10459
                     /locus_tag="VIA51_000974"
     CDS             8438..10459
                     /locus_tag="VIA51_000974"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEQ8682920.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQSKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANNHFYHQLKQHKGLLKQHKGLFIEEVYHTEFEY
                     GLVLFWQAQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQS
                     QKILAQLQVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGD
                     MFYLDSYDVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTF
                     FGMMVADLGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGF
                     DLPVALLSTKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFI
                     LLGLLLFILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGI
                     SSYLSDLVSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLS
                     MLSGYVHGARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            10461..10940
                     /locus_tag="VIA51_000975"
     CDS             10461..10940
                     /locus_tag="VIA51_000975"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEQ8682921.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            11008..11592
                     /locus_tag="VIA51_000976"
     CDS             11008..11592
                     /locus_tag="VIA51_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEQ8682922.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            11608..12606
                     /locus_tag="VIA51_000977"
     CDS             11608..12606
                     /locus_tag="VIA51_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEQ8682923.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            12603..12923
                     /locus_tag="VIA51_000978"
     CDS             12603..12923
                     /locus_tag="VIA51_000978"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEQ8682924.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEVLTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            13124..14899
                     /locus_tag="VIA51_000979"
     CDS             13124..14899
                     /locus_tag="VIA51_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEQ8682925.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            14900..16315
                     /locus_tag="VIA51_000980"
     CDS             14900..16315
                     /locus_tag="VIA51_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEQ8682926.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            16360..16986
                     /locus_tag="VIA51_000981"
     CDS             16360..16986
                     /locus_tag="VIA51_000981"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEQ8682927.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLKETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(17106..18368)
                     /locus_tag="VIA51_000982"
     CDS             complement(17106..18368)
                     /locus_tag="VIA51_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEQ8682928.1"
                     /translation="MADFNFDIDQIADNAVIKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKITRA"
     gene            complement(18381..19259)
                     /locus_tag="VIA51_000983"
     CDS             complement(18381..19259)
                     /locus_tag="VIA51_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682929.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPQIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHDANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            19697..20989
                     /locus_tag="VIA51_000984"
     CDS             19697..20989
                     /locus_tag="VIA51_000984"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEQ8682930.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLGFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            21316..22359
                     /locus_tag="VIA51_000985"
     CDS             21316..22359
                     /locus_tag="VIA51_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8682931.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIETAK
                     KAIIEGTITVPEN"
     gene            22532..23071
                     /gene="nusG"
                     /locus_tag="VIA51_000986"
     CDS             22532..23071
                     /gene="nusG"
                     /locus_tag="VIA51_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEQ8682932.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            23442..24797
                     /gene="nga"
                     /locus_tag="VIA51_000987"
     CDS             23442..24797
                     /gene="nga"
                     /locus_tag="VIA51_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEQ8682933.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFVSPM
                     RIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            24802..25287
                     /locus_tag="VIA51_000988"
     CDS             24802..25287
                     /locus_tag="VIA51_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEQ8682934.1"
                     /translation="MYKVPKSLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMVHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            25311..27026
                     /gene="slo"
                     /locus_tag="VIA51_000989"
     CDS             25311..27026
                     /gene="slo"
                     /locus_tag="VIA51_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEQ8682935.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRS
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            27281..27712
                     /locus_tag="VIA51_000990"
     CDS             27281..27712
                     /locus_tag="VIA51_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682936.1"
                     /translation="MKQQSYQPLRFVYLLVALFAAMLLIARPVMADGENNDPANAAYY
                     KGKSAGEEAGKTAGKEASWTDLTPTNPTIPEPPSDIRETTNKQHYKDGYTDGYRDGYN
                     EGWKSQHPVLTPVKVIWDLISHWLQQFFPNNQATTTVQSMS"
     gene            complement(27898..28134)
                     /locus_tag="VIA51_000991"
     CDS             complement(27898..28134)
                     /locus_tag="VIA51_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682937.1"
                     /translation="MKKKLSLFMIATAAVVSLSLATPENQTVSANDTQVTCVGCPDCG
                     PKWSCCPLTCMRDLLRGWGKSAAYYCTWGYYYSE"
     gene            complement(28544..28687)
                     /locus_tag="VIA51_000992"
     CDS             complement(28544..28687)
                     /locus_tag="VIA51_000992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682938.1"
                     /translation="MIATAAVAGLSLATLGSHQTVSANDASYSNGFYGHTGPDSWLLY
                     TVW"
BASE COUNT         8862 a         5049 c         6114 g         8685 t
ORIGIN      
        1 ttatttaatt attcaaatat aacaaagata ttgttgatga gtgaagcgcc attctttttg
       61 ctataaataa gggttatgga agcaataaaa aaatcatagt tgtttatgaa aacgctgtca
      121 taataaaaag gggacaaaag tgttttttgt ggatttaaac ttattgataa ctaaatgaac
      181 taaagaaacg cttattaata ttatcgacag gttactggtc aaaagaacaa aagtgctttt
      241 ggacaatgtg aaaggaattg acaacatgaa taacatcaaa accaaaaaaa ggtttatgga
      301 tcgctatatt gatggcttta tgaaatggat gccagaatcg ctttttatct gttttatttt
      361 aaccttttta gtcgttacta tgtctgtgtt gatgacggat agtcccttta ttggtacgga
      421 aaagacgggc gggattatct atggctgggt aaatggtttt tgggggctgt tgtcctttgc
      481 catgcagatg actattttac ttgcgacagg gaatgctgta gcgagttctc cacctgctca
      541 taagatgttt aagtcccttg ccaaactgcc tcaaaccagg actcagattt ttatcttttc
      601 cattgtagta ggctctatct ttggcttttt acactggggt cttggtatga tggttgctat
      661 tgtgtttggg aaagagttgc ttgttcaggc taggcaaaaa gggattaagg tgcatacgcc
      721 tttgtttgtt gctactttat tttttacctt tttaccagct acttctggtc tatctggtgc
      781 tgcggtgctt tattcggcta ctccagatta tttgcgaaat agtgtcgcag atgcttataa
      841 acaggttgtt cctgaaagtg ttcctctgac agaatcagtt ttgaatcttc catttatcag
      901 tcttttagtg gtgtgtatgc tggaaccgct ttgctttgct ttattggcgc acccaaaaga
      961 tgaaactaaa atcatggaac ttgatgatga gatctatcac catagtcttg ataccgcttc
     1021 acatgttgtt attgcaagaa acacacctgc tgaaaagatg aacgcatctc gcttagtgat
     1081 gtatcttgtt ggtggggcca ttgttagcta tagcctttat catttttcgg tggtgggctt
     1141 gtctggtcta gatctcaatt gttttaactt tttattttta ggcttaggct tgcttctttg
     1201 tggtcaacaa ggaccagaat attatggttc cttattcaaa gatggggtca tgtcatcttg
     1261 gggcttggtg cttcagtttc cattttacgc tggtattttt ggaatcattc aaagtacagg
     1321 tttaggatta gagatttccc atttctttgt cgctatttca aatgggacaa catggccggt
     1381 ctttgcttat ctttactcgg ctttgctgaa tattgcggta ccatcaggag gctcaaaatt
     1441 tgtgattgaa gctccctata tcgtccctgc aactatcgaa gttggtaatg acttaggtaa
     1501 gattttgcag gcttatcaat taggagatgc cacaacaaac ttgatagttc ctttttgggc
     1561 cttatcttac ctctcaaact tcaaactaaa attcaatcaa attgtggctt atactattcc
     1621 ttgtgtcttg gtggtcacag gtattgccat catttaccta tttgtatttt aggaaataac
     1681 tacatgaaac gcttgggatt gtttccttca ggcgtttttt taaggtctga gtccagcaat
     1741 tagaagcgct ggttcatgaa ataatctaag atggtgtgct tgatataatg ttttaaatgg
     1801 cttgttttgt tgtgcttgag agaggctaga acaacttccc attttggatg ttcggtcagt
     1861 tggacctcca ctaaaccgtc catatgagca aaatgagtaa taggtcttgg taggattgtt
     1921 aggtaagagg aatagcgcgt gcaatttaat aaaaaatccc acgaggcaga ataacatttg
     1981 actacaggaa gactatttgc ttcttcaaat aaggtggtaa gctgatgatt aatcataaag
     2041 gttttatcaa aagttactaa gttttgacga tgtaatgctt tgatagagat gttaggatta
     2101 ctatcaaacg tctcttgaaa ggttttgtga ctcatataaa ggcagagttg atctcttagg
     2161 agaatgtcga tatcagcaat agtagcatct agtgtagtgg gtgttaataa aatcgcaaaa
     2221 tcgacttctt ttagaaacag tttttttgca gttcataagc acccgtttct acaatatgaa
     2281 atttaacttc gggattttct tcgatgagtt ttggaatgag ctcagaaaaa acaatgccag
     2341 agatgagttg aggaataccg attgaaattt ctcctttgta ttttttggat tcactccgca
     2401 aatcagccat taattgctca tgtgatgcga taaccacctt agcattttca aaaaagcgtt
     2461 cgccgactga agttagtcca actagacgcc ctttttgacg ctggaataaa acgactcctt
     2521 cttctttttc gatagtcttg atataactac taagggcggg ttgcgaaata tgactttttt
     2581 gggctgcttt ggttaagtta aagtcacaat taacaatctc aataaaataa gccaagcttg
     2641 agatattcat attttcctct ttcgataacg tttagttata gcatatataa aaaaacgata
     2701 tttgtttatt atagttcaca ttatataata aaaatgtaag cgtttcaata atgaaaaagg
     2761 agaagtttct atgactaaag aagtggtgat cacatctgct tatcgtaccc cgataggaaa
     2821 ttttggagga gtctttaaat ctttatcagc cgtagatttg ggggtgacag ttgttacaaa
     2881 aattttagct gataccggtc ttaaaagtga tgccattgat gaagtgatct ttgggaatgt
     2941 gttacatgca ggtctgggtc aaaatgttgc ccggcaagta gcgctaaatg cggggctttc
     3001 ttatgatacc cctgctttta cgattgatat ggtctgtggt tctggcttaa aagcagttga
     3061 gttaggtgct caaaagattc aaacgggcaa cgctgatatt gttttagttg gtggtaccga
     3121 aaacatgagt caagcacctt acgttttaca aggccaacgt tggggatctc gtatgggaga
     3181 tagtaaagta gtagatacca tgcttaaaga tgggttgagt gatgcttttg caggttatca
     3241 catgggtata acagccgaaa atattgtgca acagtatgga ctgaccagag aagaacaaga
     3301 tgcctttgca gctgatagcc aacgtaaagc ccaacttgcc atagaaaaag gtcgtttcaa
     3361 agaagagatt gcacctgtca ctattcctca gcgtaaaggt gaacctttac tcgttgatca
     3421 agatgaatac cctaaatttg gaacgacagt ggataagtta gcaaagttac gccctgcttt
     3481 tatcaaagat gaggggacag taactgctgg taatgcttca ggaatcaatg atggagcagc
     3541 ggcaatttta ttgatgagta aagaaaaagc tgaagaatta gggctcccta ttttagctaa
     3601 aatcactagt tatgcaagtg caggtgtaga cccaagtatt atgggctgcg gaccaatacc
     3661 tgctacgaaa aaggctcttg caaaggctca gctgacaatt gatgacattg atttgattga
     3721 agcaaacgaa gcttttgctg ctcaggcttt agcggtttca cgagaccttg gttttgacaa
     3781 tgaaaaagtt aatgtcaatg gaggagctat tgctttgggt cacccgattg gagcatcagg
     3841 tgctcgtatt ttagtcacct tattagcaga aatggctaag cgtgatgtga gacatggctt
     3901 agcaacgctt tgtattggtg gtggccaagg tcaaagtatc atcgtaacaa gatagaaggt
     3961 aaccgtatga aagagaataa aagaatagca atagcagaag ctatcagtca tattaaagat
     4021 ggtgacacga ttatggtcgg tggttttatg gctaatggaa caccagaagc gttaattgat
     4081 gcactggttg acaaaggcac aaaagactta accttgatct gtaatgatgc tggttttgtt
     4141 gatcgcggtg ttggaaaaat ggtggctaat catcaattca aaaccattta tgcaacacat
     4201 attggattaa ataaagaagc tgggcgccaa atgactgccg gtgaaacgac gattgagctc
     4261 attcctcaag gaaccttcgc cgaaaaaatt cgcatcggag cttatggcat tggtggcttt
     4321 tacacgccaa caggggtagg aaccttagtg gcagaaggca aggaaacaaa aaccatcaag
     4381 ggaaaaacct atctcttaga atacccattt gaggcagatg tcgccttgat atttgctaat
     4441 caagctgatg aaatgggaaa tttacagtat agtggttctg aaaataattt taatcaattg
     4501 atggcagctt gtgcaaaaac aacaattgtt caggcgcgag aaatagtacc agtcggcacc
     4561 atacaaccag aatgcgttca tacaccacat atttttgtag attacattgt taaagaagga
     4621 gtatagttat ggcggttgca ttaagtaaag aagagattca aaatcgtatt gcaaagcgtg
     4681 tggccaaaga attagaagat ggtactttgg taaatttagg tattggtcta ccaaccaaag
     4741 tagcaaattt tgtgcctgaa gaaatgacag tgtattttca atctgaaaat gggtttattg
     4801 gactaggtcc taagtcagat gatccgaatt cgactatcgt taatgcagga ggacagcctg
     4861 tgacggttta tccaggagcc gctttcttta atagtgcaga ttcttttggc attatacgtg
     4921 gtggtcatgt tgatttgacc gtcttgggtg ctttagaaat tgcagaaaat ggagatatcg
     4981 ccaattacct gattccaggc aaaatggttc ctggtatggg aggagcgatg gatttattag
     5041 ttggtgctaa aaaagtcatc gtagctatgg agcataccaa taaaggaaag cataagctcc
     5101 taaaagaatg taccttacct ttaacagcaa aaggtgtggt tgaccttatt atcacagaaa
     5161 tgggtgtgtt taaagtaacg ccagatggta tccaagtaat tgaaatcagt gaagggttta
     5221 cttttgatga ggttcaagct gcgacaggtg tacctctaag catagctgaa ggttaatgac
     5281 cagtagcctt ttcttgccat aaaggcatat tgagtaaaaa aaacgtcagt catcggtata
     5341 tcagagattg tgatgcttat ctgaaatact tttaactggc gttttatggt gatttggtta
     5401 ttgatcggct tcaatttttt taaggtagcg gtaaacactt ggttcggaaa tacatagaat
     5461 atcagcgact tttgagacgg ctccttttag ctgaaagacc cctttttcat aaagcttggc
     5521 aacaatgtct attttgacat cttggctaag atgtacattg tgtctcagta acgagggatc
     5581 aataatttga ccgataatat cttggatgtt agaggttaaa atttcaacag cttcttctgg
     5641 ctggggtgtg actgttttag gctctttagc agttgggatg aaatgttcta aattgagatt
     5701 gacaagtttt aagaggtccc tagctactcc ttgataggct gaaatatcta agttaataca
     5761 tagcattccc tcgagattac cctttttatc tttaataaaa aaagtagatc cccgaacttc
     5821 tttgtgctga ggactaacga ttgctttgta attggtcaca aaatcttttt ccttatagac
     5881 tttattagta atcaaatcaa gagcaaaggt ggtgagagga gactgtttag accgtccact
     5941 gatatgacta ttaacgagtt ctccaatata gatatcattt ttatcaatca catgtaaaat
     6001 aatttcatag ttatcaccta agacatcgtg aagaaatgtg ataaccgttt tccagtagtt
     6061 tagcgtttct ttatccatgt caaacttcct atatctatct tcttatttac aaatatagta
     6121 atacatttta gactaaaaaa caattgccaa tcaccttaat aataattttt tatcaaaaag
     6181 agaatttatt attgactgtg aatgcggttt cctgtaaaat ttaactatat tatcaatgag
     6241 gaggttcgta tatgaagagc tacccagaac caatgggccc ttattcaact tatacgattg
     6301 aaggacattt tctatacacc gcaggccaat taccccttaa tccagtgaca ggtcaattgt
     6361 cagatggttt tgaggcacag tgtcgccagg tttttgttaa tttacaatct attttggcag
     6421 agcaaaagtt ggacttgaat catatctata agctaaatgt gtatttaaca gatgtgacca
     6481 atgtggaaat attaaatcat gtcatgactg atttgtttga agagccctac cctgttcgga
     6541 cagcggttca agtgtcggcg cttcctttgc aagctttgat tgaagtcgaa gctgtcgcca
     6601 gagtgaagca gttatagtgt cttatgtaat gagatagatt ggtggaatag attatggata
     6661 ttattattgg aacaagtctt ttgattcttg ttttagctat ttttagcttg tttaactata
     6721 aggctcctca tggtgccaag gcaatgggag ctttggcttc ggcagcttgt gcctcttttt
     6781 tagttgaagc ctttcaagat tctttttttg gtaaggtttt aggctttcag tttctaagtg
     6841 aagtaggcgg agcaaatggc tcattatcag gggtagctgc tgctatcttg gttgccattg
     6901 caattggtgt gtctccaggt tatgccgttt tgattggttt gtcagtttca ggaacgggta
     6961 ttatcccagg ttttgtggct gggtatgtgg tatctttttt aatcaagtgg atggaaaaaa
     7021 atattcctgg tgggcttgat ttaatctcga ttattattgt cggtgcacca ttaactcgtt
     7081 tcttggcgca gttaattacg ccagtgatca atagtacttt attgactatt ggagacatcc
     7141 tgacctcaag tgctaatagc aaccctatta tcatgggaat gatactaggc ggtacgattg
     7201 ttgttgtagc aacagctccg ctgtcatcaa tggctttgac agccatgctt ggtctaacag
     7261 gtattccgat ggctataggt gccttatctg tctttggctc ttcttttatg aatggtgttc
     7321 ttttttaccg attaaaattg ggtgaaagaa aagacaatat tgcttttgct attgaaccac
     7381 taacgcaggc agatgtgacg tcagccaatc ccattccgat ttatgtgact aattttgttg
     7441 gtggtgctgc atgtggtgtt ttgatcgccc taatgaaatt ggttaatgat acgccaggga
     7501 cagctactcc gattgccggt tttgcggtga tgtttgccta taatcctgtc gctaaagtgt
     7561 tgataacagc ccttggatgt attattatca gcttaattgt gggttatatt ggaggttctg
     7621 tctttaaaaa ttaccgttta gtaacaaaac aagaattaca agcgagaaac taataaacat
     7681 ctttttgaca ggacttttaa caagatagca gttatactgt tatcacattg gcttggctat
     7741 tggctggtaa aggtacctta ccgtcaacta gatcaaggtt actaaatgcc taaagaagta
     7801 taagataaca cacgaaagac agcaatacaa agctttagag ttctgtgtca tcttactgct
     7861 ttgacaggtt tttagctaac ctttttctga actaagccat tgtttttatg gatagaattg
     7921 aaagcgctta acttaaagat gctgttcgtt taattaagcc attatcctat ctcaaaaaag
     7981 ctgttagtag ataggttaga gatttagctc tagcttatat tcactggttg attaaccccc
     8041 caaaagtagc ctttcttgta gctttgtttt taagtaccta gtgagtcaaa gaattagcaa
     8101 tagataaaga taaggagttg atatgtgatg aataccctat tgtcactaat gaatagtatc
     8161 gaacaagagg ctagaacaat ttatgacagt tacgatgcta agaaaaaagc tctagctgac
     8221 aaaaaagaag aagagttaaa gcagctgttc cttgagtacg aacaagaaac tcagctacta
     8281 ttagaagcta aacgtgaggt gttttttgaa gctaatcgtc aagaacaaaa agcttcaaaa
     8341 aagagattag cgacgcaaca gctagccctt catgccattt tagaagagca taagctaacc
     8401 gttgttaggg agttagtgga taaggtggtg gagacatatg gccattagtc aaatgaaaaa
     8461 gctggcaatg gtttttgaaa aagattatct tgatcttgtt ttaaaaacac ttcaacaatc
     8521 tcaattagtt gaagttcgtg acatgaagca actaaaacat tggcaagatg cttttaacaa
     8581 aggcaacgtc aagttgccac aaatcgtcca atacgatctg acgcatcaaa aacctctact
     8641 agatgatgaa gctttacaat accttttaca aagccaacaa gagttagaaa acggccttgc
     8701 tagcttatca gcgtttttac caccaatagg aaagttaaca gccttgagac aaaaaacgcc
     8761 atctctttcg tttaaacagt tcgaagaacg ccatcgacaa caagcagctc aaacggcttt
     8821 gaaaatgatg tcacaaaaga tagagcgact agagcagctg caaagcaaaa tagaccagct
     8881 aacagaatac tgtcaggagt tagaaaagtg gcgttccttg actgttttgc ctcaggactt
     8941 agcgcaattt cattttttgt cggcaagagt tggaacgatt cctagtacag caaataatca
     9001 tttttatcat cagctaaagc agcacaaagg tcttttaaag cagcacaaag gtctttttat
     9061 tgaggaagta taccatacag aatttgagta cggccttgtc ttattttggc aagcacaaga
     9121 tacgattcat ttacagaaat atcagtttaa acccttatta tataaagaac agttactgcc
     9181 atcagaacaa cttcgtataa acaaagagtt actaacgaat tggctagctg aaaaagatag
     9241 tctactaaaa gagcttaggc agtctcaaaa gatactggca cagttacagg ttgaaataga
     9301 ctatgtcctt agtcagtatc aacggcagca aactaaaaag caattactcg gtacaagaca
     9361 tctaatagcc ttagaagggt ggatagaagc tgattcggtt aaccaattaa aagggctaat
     9421 gactaagaca ctaggtgata tgttttatct ggatagttac gatgtcacgc cagacgattg
     9481 ggaagatgtt cccattaagc tacgtaatca ccgctacatt gcaccgtttg aattggttac
     9541 agaaatgtac gctttgccaa aatatcaaga aaaagatccg acaccttttt tagctccttt
     9601 ataccttact ttttttggca tgatggtagc tgatttgggc tatggtttgt tgctatatgc
     9661 tgtgacacta gctgcattgg tcttttttaa tctccaaaaa accagtaaac ggttagtgac
     9721 cttctttaat attttagcta tttcagtagc catatggggg cttatttacg gttctttctt
     9781 tggttttgac ttacctgtgg cattattatc aactaaaacg gatgtgatta ctattttggt
     9841 tgtttctttg ctatttgggt ttgttacact tatatttggg cttttgttag gagcatggca
     9901 acaagtaagg atgaaagcat atgctacggc ctatacgtca agtctagctt ggacttttat
     9961 tttattaggt ctgctgttat ttattcttgg taagaatgta tctggccttg cttacttatc
    10021 ggttattggt aagtggcttg cattgggcaa tgcctttggg attttggttg tttctttact
    10081 aaaaagcaaa agccttttag gtctaggtag tggattatat aatttatatg gcattagctc
    10141 ttacttaagt gatttggtta gctttactcg tctaatggca ttagggcttt ctggagctag
    10201 tattggagcg gcttttaaca tgattgttgg gatttttcca ccagtcacgc gctttacagt
    10261 aggtatcttt atttttattc ttttgcatgc gatcaatatt ttcttatcaa tgctttcagg
    10321 atatgtgcat ggtgctcgtc ttattttcgt agagtttttt ggaaaatttt atgaaggtgg
    10381 aggaaaagct ttcaatcctt taaagttagc tgataattat gtcaatgtca atgaagaaac
    10441 agatttggag gacaattaac atggaacatt tagcacatta ttttacagca catggtggcg
    10501 ttttcttcgc agccttagga attgttttag ccgtagctct tagtggcatg ggctcagctt
    10561 atggtgtcgg taaaggtggt caagcggcag ctgcgctctt aaaagaagaa cccgaaaaat
    10621 ttacgtctgc gcttatcttg caactgttac ccggtagtca aggaatctac ggctttgcta
    10681 ttggtatttt aatttggatg aaactgacac cagaactttc agttaaccaa ggattagctt
    10741 actttttggt atctcttcca attgctattg ttggttattt ttcggccaag caccaaggca
    10801 atgtttctgt agctggtatg caaatcttgg ctaagcgccc taaagacttt atgaaaggtg
    10861 tcattttagc agctatggtt gaaacctatg ctattcttgc ctttgtcgtc tcctttattc
    10921 tcttaaataa aattggataa ggtatggtcc ttatctagat tttaaaaaac ggtgacacca
    10981 ctaacactat caaaaggggg aaattaggtg aatgatataa cacagttaag acaaaacgtt
    11041 cttgaaaaag cacatcaaga aggtcaacag tgcctaaaga tagcgacaga tagtcttgat
    11101 actgacttta aagagcgtca acagcaagga ctacacgatt taaaagcaaa gcgtcaaaaa
    11161 gagttaaaag ctcttgaaca gcaatttcag gttgcgcagc agcaactcaa aaatcaagaa
    11221 agacaagctc tactagcatt aaaacaagac agtataaagg agctatttga agcttctttg
    11281 gagaagatga cgaacttttc taaggaagaa gaattggctt ttttgaagca agtcttgtct
    11341 aaatatccag aacagccatt gcaagttact tttggcgaaa aaacagggca aaagttcagt
    11401 tcttatgatt gtgctgagct gagattagca tttcctcaat taagctataa tcaagagcta
    11461 attcctcagg aagcaggatt tttagtcagt ttagaccaag tcgatgacaa ttatttatac
    11521 cgttaccttt tagaatcagt tcttaaagaa gaaagctccc gcatcattga tatgcttttt
    11581 tcagagatat aggaggtttg actagcgatg ccaacatttc tagaattaaa cactactatc
    11641 agtgtcaaag aaaaagagtt attgactaaa gagcaatttg ataagctatt gcaggctccc
    11701 aatacaacaa ccttagctcg actgttgcac cagtcagtct atcacctaac tgttgacgat
    11761 ctcaacgatt tggatcggct agaatctatc ttaatggctg agctaaccaa gacctatcgc
    11821 tgggcttttg cagaaacccc tcaacctgac atagtacaat tatttacctt gcgttacacc
    11881 tatcataatg tcaaagtgtt gttaaaagct aaagctagtc aagcagatct gagtcactta
    11941 ttactaccaa ttggtgacaa gcctttggtg gctttggaac atttgattag gacgatgact
    12001 tctgatgagt ttccaaaaga ggtggtaaca gaaatccagt ccatttgggc cgaatatcaa
    12061 gattatcaag acatacgcgt cttagaaatt ggtactgact tagcttattt taaggcgttg
    12121 aaacaaatag cacaaagatt agaggaccct gttttccaac aagctgttct tattgtgatt
    12181 gatttgtata atctgattac cgtcagacgg gccaaatcgc aaaataaacc aataagtttc
    12241 atgatgcagt tattatctga tgaagcaagt agaccaagta aaacatttat cacacttgaa
    12301 gatgataagg atctgatgac gtggtttgaa aatgtaacac ctgatagcta tatgacagcc
    12361 ctaaaacctt attcagagaa acttcgccaa ggcactcttc aaacgactga gttagaatac
    12421 cttgttgatg aatgccttta ccatttattt gcgaaggcca aatatcaagt cgatgggcct
    12481 tatgtgcttg ctcgcttttt gctcgctaaa tcgtttgaag taaaaaacct acggctttta
    12541 gcggctgctt tagctaatga tttacccaaa gaacgtgtca tagaaaggat gagaccaata
    12601 gcatgaccaa aacattgtat aaagtcgggg taattggtaa cagagatgtt attctacctt
    12661 ttcagatgat tgggtttcaa acttttccag taataaaacc acaagacgct attaaccagt
    12721 tgcgtcaact agcaatggaa gactttggta ttatttatat cacagaagat attgctgcag
    12781 ctattccaga agtcctcact cactatgaca atcaagttct accagcagtc ataccattac
    12841 caactcatca aggagcgcaa gggataggcc tgtcacgcat acaagccatg gttgaaaagg
    12901 ctgtcggtca aaatatttta taacactaag acgttaggca aagaggactt atactctgtt
    12961 tgaggcttat gagtagctaa ctgatgaaat gcaaggacag gaaaattggt gaagttagca
    13021 gctgaacgca taggatagtt tgctgactat tcaaaatagt cacattaaac cttgacagta
    13081 tagattagtt agtatgattt ggaaaaaata aaggaggaaa aaggtgaacc aaggaaaaat
    13141 aataaccgtt tcgggacctc ttgttgtggc ttctgggatg caagaagcta atattcaaga
    13201 tatttgtcgt gtgggacatc ttggcttagt cggagaaatt attgaaatgc gtcgcgatca
    13261 agcgtctatt caggtttatg aggaaacatc agggatcggt ccaggagaac cagtagtgac
    13321 tactggttgt cctttgtcgg tcgagttagg cccgggcctg atttcagaaa tgtttgacgg
    13381 tattcagcga ccgcttgatc gttttcaaaa agcaacggac agcgactttt taatccgtgg
    13441 tgtggctatc ccaagtcttg atcgaaaggc taagtgggca tttattccca agctaagtgt
    13501 tggtcaagaa gtagttgcag gtgatatttt aggaactgtg caagaaacag ctgtcattga
    13561 gcaccgtatc atggttcctt ataaagtttc agggaccttg gtggctattc atgcagggga
    13621 cttcacagta acagatacag tttatgaaat taagcaggaa gacggttcca tttaccaagg
    13681 tagcctcatg cagacttggc cagttcgtca aagtcgccct gttgctcaaa agcttatccc
    13741 agtcgaacct ttggttacag gtcaacgggt tattgacacc tttttccctg ttacaaaagg
    13801 tggtgccgct gccgttcctg gaccatttgg ggcaggaaaa acagttgtgc agcatcaaat
    13861 agctaaattt gccaacgttg atattgttat ttatgtcggt tgtggggaac gcggcaacga
    13921 gatgaccgac gttttgaatg agtttccaga gttaattgac ccaaatacag gccagtccat
    13981 tatggagcgc acggtgttaa ttgcaaacac ctctaatatg ccagtagcag cgcgtgaagc
    14041 gtcgatttac acaggtatta ccattgccga atatttccgt gatatgggct attctgtggc
    14101 tatcatggca gactcgacat cacgttgggc agaagctctg cgcgagatgt caggacgcct
    14161 acaagaaatg cctggtgatg aaggctaccc ggcttactta gggagtcgta ttgccgaata
    14221 ttatgaacgg gctggtcgtg ttcggacctt gggaagtcaa gaacgtgagg gaaccattac
    14281 agccatcggc gcggtttctc ctcctggagg ggatatttca gagcctgtca ctcaaaacac
    14341 ccttcggatt gtcaaagttt tctgggggct cgacgcgcct cttgcgcaac ggcgtcactt
    14401 cccagcgatt aactggctga cgtcttattc attgtatcaa gatgatgtag gaagctatat
    14461 tgaccgtaaa cagcaatcta attggtccaa caaggtaact cgtgccatgg ctattttgca
    14521 gcgtgaagcc agtctagaag aaattgtacg cttggtgggg cttgattcac tgtctgaaca
    14581 agatcgtttg accatggctg ttgcccggca aattcgggag gattatctcc agcaaaatgc
    14641 ctttgattcg gtggatacct ttacttcctt tccgaaacaa gaggccatgc taaccaatat
    14701 tttgaccttt aatgaggaag ccagcaaagc cctttctttg ggagcttatt ttaatgagat
    14761 tatggaaggc actgctcagg tacgcgatcg catcgcacgc agcaaattta tcccagaaga
    14821 aaacttagag cagattaaag ggcttactca gaaggttacc aaagagattc accacgtttt
    14881 agcaaaggga ggaatttaga tgagcgttct caaagaatat cggacggtta gcgaagtggt
    14941 tggccctttg atgattgttg atcaagttgc aggagtgcac tacaacgaat tggtagatat
    15001 tactttgcat aatggagaaa ggcgtaaagg tcaagtctta gaagtccaag gtgacaaggc
    15061 tatggtacag ctatttgaag gatcaactgg catcaaccta gccaaaacca aggttcgatt
    15121 tacagggcat cctttggaat tagccgtatc agaagatatg gtagggcgca tctttgatgg
    15181 aatggggcag cccatagacg gcggtccaga acttattccc gaaaaatacc ttgatattga
    15241 tggtcaagcg atcaatcctg tcgctcgtga ttacccagac gaatttatcc agacaggtat
    15301 ctcagctatt gatcacctca ataccctcgt tcgtggtcaa aagttaccag ttttttcggg
    15361 ctcagggtta cctcataatg aattggccgc acagattgct cgtcaggcaa ctgttctaaa
    15421 ctctgatgat aactttgcgg ttgtgtttgc agctatgggt attacttttg aagaggcaga
    15481 attctttatg aatgacttgc gtgaaacggg tgccattgat cgatctgttt tatttatcaa
    15541 tttagctaat gaccctgcta ttgaacgcat tgcaacacca cgtatagctc tgacaacagc
    15601 cgaatacttg gcttatgaaa aaggtatgca tgttttagtc atcatgacag atatgacaaa
    15661 ttattgtgaa gccttacgag aagtatcagc cgctcgcaga gaagttccag gcagacgagg
    15721 ttatcctggc tatctctata ctaatctctc caccttatat gaacgggctg gtcgcttgat
    15781 cgggaaaaaa gggtcagtga ctcaaattcc tattttaacc atgccagaag atgacattac
    15841 ccaccctatc cccgatttga caggttatat taccgaaggt cagattattt tgtcgcaaga
    15901 actatataaa aatggtttta gaccgcctat taatgtcttg ccatcgctat ctcgcctaaa
    15961 agataaaggc tcaggtgaag gtaagactcg acaagaccat gctgctacaa tgaatcagct
    16021 ctttgcagcc tatgcccaag gaaaacaagc taaggaattg gctgttgtgc tcggtgaatc
    16081 agccctttct gaaacggata aactatatgt ggcctttacc aaccggtttg aagaagaata
    16141 cattaaccaa ggattttaca ccaaccgtag cattgaagaa agtcttgact tgggttggga
    16201 attgttgtcg attttgccac gtaccgaatt aaaacgcatt aaagatgata tgttagatcg
    16261 ttatttgcct aaagcagata ccacgatgac aaaggttttt gttgcaaatg attgagttga
    16321 ccatgcaatt tcaagccctt gacgaaagga gttatatcaa tggcacgatt aaatgttaaa
    16381 ccaacacgca tggaacttag taacttgaaa aatcgcttga agacagctac aagaggtcat
    16441 aaattattaa aggacaagcg ggatgagttg atgcgccgct tcgttgattt aattcgtgaa
    16501 aacaatgagc ttcggcaaac tatcgaaaaa gaacttgctg ccaatatgaa ggagtttgtc
    16561 ttggcaaaag catccgaaaa tagtctaatg gtagaagaac tctttgctgt tccagtccat
    16621 gaagtgacct tatggattga tattgaaaat atcatgagtg tcaatgtgcc taaattccat
    16681 gtccagtcta atacggcaag agagcaagaa caaggtgagt ttgcttatag ttacctcagc
    16741 tcaaatagtg agatggacaa tactatccaa aagacaaaag aactattaga aaagctctta
    16801 cggttagctg aagttgaaaa aacttgtcaa ctaatggctg atgacattga aaagactaga
    16861 cgtcgcgtca atggcttaga gtattctatt atcccgcaac tgaaagagac gattcactac
    16921 attgagttga aattagaaga ggccgagcgt gcgagccttg ttcgtattat gaaaataaca
    16981 tcataaaaga taagtgttat atcaaacaag gcgattattc gttaagtagt aaaaaagcaa
    17041 gccatcaaag ggattaacct aactgatggc ttgcttttta agtagcgtga caggtgatgt
    17101 ttagcttatg cgcgagttat tttatcaatt gttttttgag tttccttgcc ttcactaaga
    17161 agtgcttgca caatattttg gtcacgtagt ttgacagaat cgttaatggt ttcggcagac
    17221 ctgataatag cactttctag ttgtgctcgt tctttgcgtc catgatcaat cgccgcaatg
    17281 atcccattat tttgtgctac taaactttct gccagacttg tcacagattt catagacaaa
    17341 gtagggtttt gtgctgattg ttccaatgct gggatggctt ctttacttgt ttctgctagc
    17401 atctgaaggg cagcattatt agcattaata atggcatcag cagtcattcc agatttaacc
    17461 gattgttgca tcatgcctaa ctgagcaata gatagtttca tcgttggaat ggtattgcgg
    17521 cgtaacatgc ctagtttttg acgcatgtca gaagagacct tgactagatt acgcatttgc
    17581 ggagttgtcg cccaagcaac atagaggcga ctcaagtatt cggtgtgttg ttgttcgaga
    17641 gtgttgatga cttcggtagt tcttgccaaa agatcagctt ttatttgata gtctggtgta
    17701 gcactgtctt tggtttttag gtctttttgt aaagccgcag cgcgctgact agcttctttt
    17761 tgactagctt cgataaaagc aatgacgcct accaaatgtt caatggactt agtattatct
    17821 tcaattaaca attctgctga gacaatattg cgagctaagg tatcttcttg cttgacaacc
    17881 gctgcagcca tactatccat tttttgctca atgttttgag aatcaaaata aaactcttgc
    17941 agggtatcac ggctttgttt aaagagtttt tgaagaaagt ttggcttttt atcaaggtcc
    18001 acaggtgtgg catccttgta tttagcgata aaaccattga gttcacgatt ggttgatttt
    18061 aaaagatcat ccacttgtgg aatctgtaat tttttttgct ctgccaagat atgattaacc
    18121 gttgcattga ccccttcaac agcagactga ccaaaatcaa gtagcgcatt ttggtctgcc
    18181 aaaaaggtat ctaccaatgc cggggctttg gcagtaatag ctgtctgctg gtcagcactt
    18241 agtttctcaa aaaaagagat ttggccattt gtgtcagttg gtaagtctga gataatatcg
    18301 gtggttttat cggttttgat aacagcattg tcagcaattt ggtcaatgtc aaaattaaaa
    18361 tctgccataa agggactcct ttagtctttt tggtgatgcg ttgttcgtct ttgagtagca
    18421 ccttgcatga ttcgaaggct aatatcaaaa tctttaagat cactttcatt gagtcgacga
    18481 agggtttcgt caagatcttc atcaaattgt tggatagctt gtttggcttg ttctaaacga
    18541 gcagcagcgt tatagtaatt tttaggctct tctttgattt ttaagtagcc tgttaagata
    18601 tcctcaaacc tcctcatgtt agcatcatgc agcgcaagca attcttcttg attgtcggct
    18661 ccttggattt tagcaaggat agcttgatga tctgtctgaa tattatcata atacggtttg
    18721 agctcaggtg ctttgttaat aagattagga gatggggttt tcaaaggctg agggttaaga
    18781 gttgtggcaa tctgcagtgt ttcgagttga agggtaatat cactttcaac gtcattggct
    18841 tttttggtga tacgacgata aatttgggga tctaactggt cttttaacgt aatagctttt
    18901 gctttgatgt cactaagttg tggtaataat tgctgagcta gtacgttata ttggaagtca
    18961 tcatggtctg ccagataagt gtctaacagc cgaactttac gatcagctag ctgaattttt
    19021 gcttttagat cttctaattg tttggcaatc ttggcctttg ctagccgctt ttgatgagat
    19081 ctaacacgaa aaatagcata acctgtacca ccaatggcta tggcaggcaa aatgtctaga
    19141 agtgactcag taaaagaaga gccacctata aagcttgaaa tcataaaaaa agcaatgatt
    19201 agccaaatcc agtttagtga tttctttttt gtgctcgtgc ggtcatactt tctaatcatg
    19261 tgatatttcc tcgatatgtt tttactggct atctcataga ggtaacttac tattatttta
    19321 ccttaaaacc gctatttctg aaagaaaaga gctaatgttt taagagaatc gtttaaccct
    19381 gctaaagctt aggagaaacg aggttaaaag cttttctctt ataatgttcg tttttttagg
    19441 attgtttatc atggttaaaa aaagagtttc tctttttcct taataatgct aagaaatcta
    19501 gcagaaaaaa tcattttttg ctataataag ttgtaagata tatgctagca ggtgagattc
    19561 ctgcctgttt tctttaaata tcaagagcta cattgctgat cttacagatc tgaccttctt
    19621 tttggttttt aagcagtggt tagcttgcct atgattttta ttgagaataa gtgtttcaga
    19681 aagttaggac aatgatatga catctgtagt tgttgttggt acccagtggg gtgacgaagg
    19741 taaaggtaaa atcactgatt tcttgtcagc ggatgcagaa gtaattgctc gctatcaagg
    19801 tggtgataat gctggtcata cgatcgtgat tgatggtaag aagtttaaac ttcacttgat
    19861 cccatcagga attttcttcc cgcaaaaaat ttccgttatt ggtaatggcg ttgtggtcaa
    19921 ccccaaatct ttggtcaaag agttggcgta cctgcatgat gaaggagtga cgacagataa
    19981 ccttcgcatt tcagaccgag ctcatgttat tttaccttat catatccagc tggatcaact
    20041 gcaagaagat gcaaaaggtg acaataaaat cggaacaact attaaaggga ttggtccagc
    20101 ttatatggat aaagctgctc gagttggtat ccgtatcgca gatttactgg ataaggatat
    20161 ctttgcagag cgcctacgca ttaatttagc tgagaaaaac cgtttatttg aaaaaatgta
    20221 tgacagtaca cctcttggtt ttgatgctat ctttgaggag tactatgctt acggtcaaga
    20281 aatcaagcaa tatgtgacag atacttctgt gattttaaat gatgcacttg atgctggtaa
    20341 acgtgttctt tttgaaggtg ctcaaggggt tatgcttgat attgaccaag gaacttaccc
    20401 atttgtaacg tcttcaaacc cagttgctgg tggtgtaacc attggttctg gtgttggccc
    20461 aagtaaaatc aacaaagtag ttggtgtctg taaagcctac acaagccgtg tcggtgatgg
    20521 gccattccct acagaactct ttgatgaagt gggtgagcgc attcgtgaag tgggtcatga
    20581 gtacgggaca acgaccggcc gtccacgtcg tgtcggttgg tttgactcag ttgttatgcg
    20641 ccatagtcgt cgtgtgtcag ggattactaa cctctctctg aattcaattg atgttctttc
    20701 agggcttgat acggttaaga tttgtgtggc ttatgacctt gatgggaaac gtattgacta
    20761 ttacccagca agccttgaac aactcaaacg ttgcaaacca atctatgaag aattaccagg
    20821 ctggcaagag gacatcacag gtgttcgtag ccttgatgag cttcctgaaa atgcccgcaa
    20881 ctacgttcgt cgtgttggag aattggttgg cgttcgcatt tcaaccttct cagttggtcc
    20941 agggcgtgaa cagaccaata ttcttgagtc agtctgggca tctatctaag gtgtctagta
    21001 tgacaaagag ttggatagcg tttccagctc tttttaccgc ttgttggatt gtatagttag
    21061 tcatgctatt actagtagct tgagttttgt cgttgtctta tctccttaag aggtgatttt
    21121 tgaggagata acgggtttta ccagttgatc tcactttctc gttcggtcat tttggtgaaa
    21181 aagagatttt tcagcaaaaa tagtaggata aaactgattt ttttgatata ctaaactttt
    21241 cgttctagag cataagtaga acgttaacaa tgacacatca ctttaggatt aaacatttag
    21301 gaggttcatt ttcacatgaa caaaaaagta atgtcacttg gtcttgtttc gactgcccta
    21361 ttcacattag gaggctgcac caataactcc tctaaacaaa caactgacaa ttcattaaaa
    21421 atcgctatga tcactaatca gacgggtatt gatgacaagt catttaacca gtcagcctgg
    21481 gaaggcttac aagcttgggg aaaagaaaat aaacttgaaa aaggaaaagg ctatgattat
    21541 ttccaatcag ccaatgaatc agagtttacc acaaaccttg agtcagcagt aaccaatggt
    21601 tataatcttg tttttgggat tggatttcca ttacatgacg ctgtagaaaa agtagccgca
    21661 aacaatcctg acaaccattt tgcaattgtg gatgatgtga ttaaaggtca aaaaaatgtt
    21721 gcaagtatca ccttttcaga ccatgaagcg gcatacctag ccggtgttgc agcagctaaa
    21781 acgacaaaaa ccaagcaagt tggttttgta ggtggtatgg aaggagatgt tgtcaagcgc
    21841 tttgaaaaag gttttgaagc tggtgtgaaa tcagtagatg ataccatcaa agtaagagtt
    21901 gcttatgcag gctcttttgc agatgctgcc aaaggcaaga cgattgcagc tgctcaatat
    21961 gctgaaggcg cagatgttat ttatcatgca gcaggaggca caggggcggg tgtctttagc
    22021 gaagctaagt ctatcaacga aaaacgtaaa gaagaagata aggtttgggt tattggtgtt
    22081 gaccgtgacc aaagtgaaga tggaaaatac accacaaaag atggcaagtc agctaatttt
    22141 gttttgacct caagtatcaa ggaagtcgga aaagctttag taaaagtagc cgtaaaaacc
    22201 tcagaaggcc aattcccagg tggtcaaata accacttttg gtttaaaaga aggtggtgtt
    22261 agccttacaa cggatgctct gacacaagac actaaaaaag ctattgagac tgctaaaaaa
    22321 gcgattatcg aaggaaccat cacagttcct gaaaactaaa actgtacaat accgtccaga
    22381 gtcgtcacga accgactttg gactttttaa taaaggtgtc aagtagctcc acagatacgt
    22441 tgacaccagc cctgtctttt attataatga aggtgataga aaacagcgca aaagccaaaa
    22501 aaagggcttt tttataatga aaggaaacat catgctagat tcatttgata agggctggtt
    22561 cgtcctccaa acttactcag gctacgaaaa caaagtaaaa gaaaacctct tgcaacgtgc
    22621 ccaaacctat aacatgttgg acaatatttt gcgcgtcgaa attccgacac aaacggttaa
    22681 cgttgaaaaa aatgggcaaa ccaaagaaat cgaagaaaat cgctttccag ggtatgtctt
    22741 ggttgaaatg gtcatgacag atgaagcttg gtttgttgtg cgtaacacac caaacgttac
    22801 aggttttgtg ggatcacacg ggaaccgatc aaaaccaaca ccacttcttg aagaagaaat
    22861 ccgtgctatc ttgttgtcta tgggtcaaac cattgatgtc tttgatacca atatcaaaga
    22921 aggtgatgtg gttcagatca tagacggtgc ctttatggga caagaaggtc gtgtggtaga
    22981 aatcgaaaac aacaaagtga agctgatgct caacatgttt ggctctgaaa cagtagcaga
    23041 agttgaactt tatcaaattg cagaactata ggctctcaaa ggtctgatgg tataagtatt
    23101 accatcagac cttttttagt tggcagtgaa gcgtgtttac aaaccaatgg atgactattg
    23161 ttaacatcat tgtaatcaga aataattaac agatctatta ctgataacgg tgctactatc
    23221 aaatatttaa ctagtacttt taatctggtt taaatagaac agatgtgaag gttctgtgat
    23281 aataagatgg aaatatcccc ttgaaacttg taacagttgg ctacttgttt ttttgtgttc
    23341 atttttttga tagaaaagcc taaaacgatg ttaataaatc gcattgacaa aaactagttg
    23401 ttaatgtata gtttacttaa aaataatata aggtggttta catgagaaac aaaaaagtaa
    23461 cattagctca tattgtcgca aagacaagtg ttgctattgc tttggctgga gcaatgggta
    23521 gcagtttatt agctaatagc acaacgtacg ctgttagtgg caaagaaaat aaaaaaagcg
    23581 atgtcaaata tgaaacgacc aaagttatgg aagctaacgc aacttcctct aaagaagaca
    23641 atcatgtcat gcacacatta gacggctcaa tgagtactgt ctgggaggaa aattcacctg
    23701 gtggtggcgt tggtgaggta ctttcctaca agtttgtttc cccgatgcgt attgggagaa
    23761 ttttaattgt gaatggagat acatctagca aggagaatta ctacaagaaa aatagaattg
    23821 caaaggctga tgttaaatac tataacggga ataaattggt cctctttcaa aaaattgaat
    23881 taggcgacac ctacactaaa aaaccgcatc acattgagat tgataaaaaa ttagatgttg
    23941 atcgtattga tattgaggta acagaggtcc atcagggaca aaacaaggat attttagcct
    24001 tgtcagaggt cacttttggc aatatggaac gcgatctttt tgaaaaaaag tttaaagaaa
    24061 ttaaagataa atgggtaaca gataaacaag cagatgagtt tattgaaact gccgacaagt
    24121 atgctgataa agctgttcag atgtctgctg ttgcgtcacg tgctgagtat taccggatgt
    24181 acgttagccg caaataccac tacaaaaaag agtttgttga aaaactaaaa caagtctaca
    24241 aagaaagcgg agcttctcac gttacaagta aaaaagattt gatgttagct tttgatgatg
    24301 ctaaaagaaa gtcaacgatt ggtcgacaag aaaacggtct ttttgtgaca agttttgctg
    24361 aagatatggc attgctcttt actgatcaag gtaagttaaa atcagctgac caaattgaaa
    24421 atataaaagg tgtcgatagc ggaaaatata gcgatggagt ttatcaatat gagtacgatt
    24481 ctgaactaac aaaaaacatt gataagctag gctatatccg aacagctagc ggagataccc
    24541 ctggagcaaa ttcgctcaac attcctggtt gccaaacgtg gtcaggaaaa cacattgaaa
    24601 attcagaaag tgagttaatt ttcccatcga ttagtgttaa agatctaaaa tctaaagctg
    24661 tcttagcaga gattgatgcc aaaggctatt ttgaaattat tgatcctacc atcattgctc
    24721 caaatggtga ccataaaaaa gtaactggtc gcttcaaaat taagaaaatg caagatagaa
    24781 tgcaagatag gaagtaacaa tatgtataag gtgccaaaga gtttagaaca ttaccaaaaa
    24841 atgtttcaaa aagaagtaac tgttaatgat ttaaaaaaat acttgatagg tagtgacaaa
    24901 gagtatcgta tcactagaag agactcctat atgggagata tttctgatcc agaagttatt
    24961 ttagagtatg gggtttaccc tgctttcata aaaggctata cccaattgaa agctaacatc
    25021 gaagaagcat tattagaaat gtcaaatagc ggtcaagcat tagacattta ccaagcggtt
    25081 caaaccctaa acgctgaaaa catgttatta aattattacg aaagcttgcc attttattta
    25141 aaccgtcaaa gcatactagc taatataacc aaagcgttaa aagatgcgca tattagagag
    25201 gctatggtac attacaaatt aggagaattt gctcactatc aagatactat gcttgatatg
    25261 gtcgaaagaa caatagaaac attttagaat gataaaaagg tatgaaggac atgtctaaca
    25321 aaaaaacatt taaaaaatac agtcgcgtcg ctgggctact aacggcagct cttatcattg
    25381 gtaatcttgt tactgctaat gctgaatcga acaaacaaaa cactgctagt acagaaacca
    25441 caacgacaaa tgagcaacca aagccagaaa gtagtgagct aactaccgaa aaagcaggtc
    25501 agaaaatgga tgatatgctt aactctaacg atatgattaa gcttgctccc aaagaaatgc
    25561 cactagaatc tgcagaaaaa gaagaaaaaa agtcagaaga caaaaaaaag agcgaagaag
    25621 atcacactga agaaatcaat gacaagattt attcactaaa ttataatgag cttgaagtac
    25681 ttgctaaaaa tggtgaaacc attgaaaatt ttgttcctaa agaaggcgtt aagaaagctg
    25741 ataaatttat tgtcattgaa agaaagaaaa aaaatatcaa cactacacca gtcgatattt
    25801 ccatcattga ctctgtcact gataggacct atccagcagc ccttcagctg gctaataaag
    25861 gttttaccga aaacaaacca gacgcggtag tcaccaagcg aaacccacaa aaaatccata
    25921 ttgatttacc aggtatggga gacaaagcaa cggttgaggt caatgaccct acctatgcca
    25981 atgtttcaac agctattgat aatcttgtta accaatggca tgataattat tctggtggta
    26041 atacgcttcc tgccagaaca caatatactg aatcaatggt atattctaaa tcacagattg
    26101 aagcagctct aaatgttaat agtaaaatct tagatggtac tttaggcatt gatttcaagt
    26161 cgatttcaaa aggtgaaaag aaggtgatga ttgcagcata caagcaaatt ttttacaccg
    26221 tatcagcaaa ccttcctaat aatcctgcgg atgtgtttga taaatcagtg acctttaaag
    26281 agttgcaacg aaaaggtgtc agcaatgaag ccccgccact ctttgtgagt aacgtagctt
    26341 atggtcgaac tgtttttgtc aaactagaaa caagttctaa aagtaatgat gttgaagcgg
    26401 cctttagtgc agctctaaaa ggaacagatg ttaaaactaa tggaaaatac tctgatattt
    26461 tagaaaatag ttcatttaca gctgtcgttt taggaggaga tgctgcagag cacaataagg
    26521 tagtcacaaa agactttgat gttattagaa acgttatcaa agataatgct accttcagta
    26581 gaaaaaaccc agcttatcct atttcataca ccagtgtttt ccttaaaaat aataaaattg
    26641 cgggtgtcaa taacagaagt gaatacgttg aaacaacatc taccgagtac acgagtggaa
    26701 aaattaacct gtctcatcaa ggtgcctatg ttgctcaata tgaaatcctt tgggatgaaa
    26761 tcaattatga tgacaaagga aaagaagtga ttacaaaacg acgttgggac aacaactggt
    26821 atagtaagac atcaccattt agcacagtta tcccactagg agctaattca cgaaatatcc
    26881 gtatcatggc tagagagtgc accggcttag cttgggaatg gtggcgaaaa gtgatcgacg
    26941 aaagagatgt gaaactgtct aaagaaatca atgtcaacat ctcaggatca accttgagcc
    27001 catatggttc gattacttat aagtaggact ggttcaagag gttcgtcaag caccttgatg
    27061 ctgcttatct cttgaggcct tgtgcctaat cctctcacaa atacagaaga aagcttgtct
    27121 atgagatacc ttcatagaca agcttttttg atatactaat caaaaaatta ttcttttctc
    27181 acatcgtgac cttgaagcta agctgcttct aatctataat actaacaagc tgctttttaa
    27241 caagcaaagc ataacataaa agggagagat aactattatc atgaaacaac aatcttacca
    27301 gcctctacgc ttcgtctacc tcttggtggc tctatttgct gctatgttgc ttatagcaag
    27361 acctgttatg gcagatgggg agaataatga cccagctaat gcagcatatt ataaagggaa
    27421 aagcgctgga gaagaagcag ggaaaacagc tggaaaagaa gctagttgga ctgatttgac
    27481 cccaactaat ccaaccattc cagaaccacc tagtgatatc agagagacta ctaataaaca
    27541 gcattataaa gacgggtata cagatgggta cagagatggt tataatgaag gctggaaatc
    27601 tcagcatccc gtcttgactc cggtcaaggt tatatgggat ttgatctctc attggctaca
    27661 gcaattcttc cccaataacc aggcaactac aacagtacaa agcatgtcat aataaaaatg
    27721 aattaaaaac agcctttaac tgctaatgtg aaaggttgtt tttttaggat atgggaatga
    27781 acaataaaaa aagagtttgt gaaaaagcct ctcggccaca caaaaaaaca atggcgtcaa
    27841 agccattgtt tttttagcat aatcaagaga ctactgtctc agactctcaa gtaattttta
    27901 ctcagagtag taatatcccc aagtgcaata atatgctgct gacttgcccc aacctcttaa
    27961 caaatcgcgc atacaggtca atggacaaca agaccatttt ggaccacaat ctggacatcc
    28021 tacacaagta acttgcgtgt catttgctga aacagtttgg ttttctggtg ttgcaaggct
    28081 aaggcttacg acagcagcag ttgcgatcat aaataaagat aatttctttt tcatttgtaa
    28141 ctccttaaat tatagtatac ctatattata ctcatattat gttaatgatt caatatcaca
    28201 ttttaatctt tttgttatgt gtttgaccga aaaaggcaaa gaaagccgat actaaagcat
    28261 ttctttatct tatataaata acattaatta ttaataatgt taatctggtt ataattatat
    28321 ttgaggtgtt acagcttttt tggtggtggt tagctagcaa ctgttacgac ttgtgttttg
    28381 ggcttgtcct tttataggcg gtatgccttt tctttttaat cttgagggat cgttagtaaa
    28441 aacgttttag ccaatcaaaa agcctagaac tgcttacgca gctctaggct tttcataacc
    28501 gtagtcttac gaagaagata gcttctatgt tacggtatta ggtttaccat actgtgtaaa
    28561 gtaaccagct gtcaggacca gtgtgtccgt agaaaccgtt actatagcta gcatcatttg
    28621 ctgaaacagt ttggtggctt cctagtgttg caaggctaag gcctgcaaca gcagcagttg
    28681 cgatcataaa taaagataat ttctttttca
//
LOCUS       DAUGQX010000024        28329 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUGQX010000024 DAUGQX010000000
VERSION     DAUGQX010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28329
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.024"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(103..861)
                     /locus_tag="VIA51_000993"
     CDS             complement(103..861)
                     /locus_tag="VIA51_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8682939.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDSKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(858..1727)
                     /locus_tag="VIA51_000994"
     CDS             complement(858..1727)
                     /locus_tag="VIA51_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8682940.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERFFKGVRLTR"
     gene            complement(2073..3071)
                     /locus_tag="VIA51_000995"
     CDS             complement(2073..3071)
                     /locus_tag="VIA51_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8682941.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAATSKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAIKKEDFPSASFIEN"
     gene            3425..5077
                     /gene="fbp54"
                     /locus_tag="VIA51_000996"
     CDS             3425..5077
                     /gene="fbp54"
                     /locus_tag="VIA51_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEQ8682942.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLAGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGTTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(5136..6383)
                     /locus_tag="VIA51_000997"
     CDS             complement(5136..6383)
                     /locus_tag="VIA51_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEQ8682943.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVGISPEPLVIFGLAEIDMSLQHFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLMYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(6373..7554)
                     /locus_tag="VIA51_000998"
     CDS             complement(6373..7554)
                     /locus_tag="VIA51_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8682944.1"
                     /translation="MPLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(7612..8088)
                     /locus_tag="VIA51_000999"
     CDS             complement(7612..8088)
                     /locus_tag="VIA51_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEQ8682945.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(8309..9349)
                     /gene="rfbB"
                     /locus_tag="VIA51_001000"
     CDS             complement(8309..9349)
                     /gene="rfbB"
                     /locus_tag="VIA51_001000"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEQ8682946.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDVIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(9593..10186)
                     /locus_tag="VIA51_001001"
     CDS             complement(9593..10186)
                     /locus_tag="VIA51_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEQ8682947.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(10186..11055)
                     /gene="rfbA"
                     /locus_tag="VIA51_001002"
     CDS             complement(10186..11055)
                     /gene="rfbA"
                     /locus_tag="VIA51_001002"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEQ8682948.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDVLIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(11113..12219)
                     /locus_tag="VIA51_001003"
     CDS             complement(11113..12219)
                     /locus_tag="VIA51_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEQ8682949.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAVKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDTYPVVMPEGEIDLIPFNQGKISVGTSHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVSGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(12259..13047)
                     /locus_tag="VIA51_001004"
     CDS             complement(12259..13047)
                     /locus_tag="VIA51_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEQ8682950.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(13037..13723)
                     /locus_tag="VIA51_001005"
     CDS             complement(13037..13723)
                     /locus_tag="VIA51_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEQ8682951.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(13795..14451)
                     /gene="nth"
                     /locus_tag="VIA51_001006"
     CDS             complement(13795..14451)
                     /gene="nth"
                     /locus_tag="VIA51_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEQ8682952.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQDTYGKSKA
                     "
     gene            complement(14448..15131)
                     /locus_tag="VIA51_001007"
     CDS             complement(14448..15131)
                     /locus_tag="VIA51_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ8682953.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTNQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(15212..15730)
                     /locus_tag="VIA51_001008"
     CDS             complement(15212..15730)
                     /locus_tag="VIA51_001008"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEQ8682954.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(15881..18091)
                     /gene="recJ"
                     /locus_tag="VIA51_001009"
     CDS             complement(15881..18091)
                     /gene="recJ"
                     /locus_tag="VIA51_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEQ8682955.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(18088..18852)
                     /locus_tag="VIA51_001010"
     CDS             complement(18088..18852)
                     /locus_tag="VIA51_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ8682956.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(18852..19781)
                     /locus_tag="VIA51_001011"
     CDS             complement(18852..19781)
                     /locus_tag="VIA51_001011"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEQ8682957.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(19796..20431)
                     /locus_tag="VIA51_001012"
     CDS             complement(19796..20431)
                     /locus_tag="VIA51_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEQ8682958.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(20424..21662)
                     /gene="hflX"
                     /locus_tag="VIA51_001013"
     CDS             complement(20424..21662)
                     /gene="hflX"
                     /locus_tag="VIA51_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEQ8682959.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(21735..22634)
                     /gene="miaA"
                     /locus_tag="VIA51_001014"
     CDS             complement(21735..22634)
                     /gene="miaA"
                     /locus_tag="VIA51_001014"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEQ8682960.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKSISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMIENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            22768..22944
                     /locus_tag="VIA51_001015"
     CDS             22768..22944
                     /locus_tag="VIA51_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEQ8682961.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(23062..23970)
                     /locus_tag="VIA51_001016"
     CDS             complement(23062..23970)
                     /locus_tag="VIA51_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEQ8682962.1"
                     /translation="MKHLKTPPLVMSGLALGTLSFGNLLATYVSIFNYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     VSSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(24207..24626)
                     /locus_tag="VIA51_001017"
     CDS             complement(24207..24626)
                     /locus_tag="VIA51_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEQ8682963.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMI
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDSLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMVEDSAVQQVLNAAH"
     gene            complement(24937..25923)
                     /locus_tag="VIA51_001018"
     CDS             complement(24937..25923)
                     /locus_tag="VIA51_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEQ8682964.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            26122..26424
                     /locus_tag="VIA51_001019"
     CDS             26122..26424
                     /locus_tag="VIA51_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682965.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(26787..26858)
                     /locus_tag="VIA51_001020"
     tRNA            complement(26787..26858)
                     /locus_tag="VIA51_001020"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(26823..26825),aa:Arg,seq:ccg)
     gene            complement(26971..28176)
                     /gene="rpsA"
                     /locus_tag="VIA51_001021"
     CDS             complement(26971..28176)
                     /gene="rpsA"
                     /locus_tag="VIA51_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEQ8682966.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
BASE COUNT         8634 a         6084 c         4978 g         8633 t
ORIGIN      
        1 gaggcgtttt ttctctaaat agccttgata ctttcagatt attttcagta tggaaatcaa
       61 aaaatcactg acttattatt agtcaatgat ttagatcgtt gattaatcaa atagttggta
      121 atagtcagta atcgtcagtt gttctttttc catttgattt aaatctttaa taatgtttcc
      181 atctttcatt acaatcagac gattcccata agttaatgca tcttccatat ggtgggtaat
      241 catcaaagct gttaagccat cttttgtcac aaactcatct gtcaattgca ttaaagattg
      301 actcgtctta gggtcaagag cagccgtatg ttcatctaat aataagagag ctggcttttt
      361 caacgttgcc attaataaac ttaaagcttg tctttgtcca ccagacaaaa gacctgctgg
      421 tgtttctaaa tgcttttcta ggccatttcc tgttcgttta accaaatcct caaaactagc
      481 taagtgctct gttatttttc gagaagccaa ggagcgtttt tctcctcttt gacgtgcgat
      541 taagagattt tcagccactg tcatccgagg ggctgttccc attttggaat cttgaaagac
      601 tcgcgatagg taaagagctc ttttttctgc tggccaatgc gtcacatcct gaccaagaat
      661 cctaatttgc ccccgtgtca aacttagcgt tcctgcaatt acattaaaaa gggttgattt
      721 tccagctcca tttcctccta aaatagttaa aaaatcatgt tcatagatag ttagtgtcac
      781 attgtccaat attgttttag catcttcaaa accattatct acgtcaactg ttgcattgat
      841 caattcaata atttttgtca tcgtgttaac ctcactccct taaagaagcg ctcttttacc
      901 actggtatca tgaggcacag tgctaaaaca agagcactaa ttaatttcaa ataacttgta
      961 ttaaaaccta gcgtaataac tactgaaatt aaaaattgat aaagaatcga gcctattaca
     1021 atagcaatca aacgttctaa aagagtcagt ccagttgagt atagtacttc accaacaatt
     1081 atgctcgcca aaccaataac aataactcca atcccttttg agacatctgc atagccatct
     1141 tgttggctca ctagagcacc tgataaagct attaaactat tagaaaccac aagtcccata
     1201 acttccatcc aatccgtgtt aataccaaaa ctcttagcca tatctttatt gtctcccgta
     1261 gcgatataag cttgacctag attagtgtaa aggaaataga tcaaaacgct aataacaatc
     1321 acaacagtta tcagacctgt taaaaggcta tttaaatcaa ttgaaaaagg taaacaatcc
     1381 tgaatacgtt tatgatcatg taaacccaag tttgctcttc ccattaccat tagcataatg
     1441 gagttacatg acgtcatcac caaaattccc gctaaaagtg ttggcatttt tcctttcgta
     1501 tataacagcc ctgttaaaaa acctgctaaa gcacctgata acataccaag taaggttgat
     1561 agaaatggat tccaccctaa gctaatagcg gtgaccgcaa cagctcctcc taaaggaaaa
     1621 gaaccttctg tagtcatgtc agggaagttt aaaatcctaa aggtcaggta gattcctaat
     1681 cctaaaactc cccatataag gccttgtgaa actgatgaaa taatcatatt tttcctcata
     1741 tttatattag cgggtaactc tcgccagtat aaaccctttc tttacattaa tttttagatt
     1801 tgttttatac ttagttcagc accgtggctt agtctttttt ttcaatcact ttgacgaaac
     1861 taagacagaa aacaaaaaag tcgagaatca tgtttaaact tactcaaaag gcaagatttt
     1921 ttacgtgtct aaaatagagc attttaaaac taaaaatgat aaaaataacc gttacatcct
     1981 caaaacgatt gtctaacttg gcatccaaat tcatctcagt gagggtgttt tttatggttt
     2041 tttcttgacc ttttatatca catgtcattg tattaattct caataaaaga agctgaagga
     2101 aaatcttctt ttttaatagc aatacctaat tctgctgcta cattcttatt aattagcggt
     2161 tgaccaatat ccacaacttt gacaggaaca tctacaacac gctttccttt gattaatttt
     2221 aacacctgat tagctgtttg aactcccaaa tcgtactgat tttgagaaat agctgccaaa
     2281 ccaccttttt caaccattcg atcaacgcta gtgtagacag gaatctttgc agccttgctg
     2341 gttgtcatga ctgatgaaaa tgcacttgct atagtattgt cttgggggat aaataccgcg
     2401 tctactttac ctaacataac tgacatcgtg gcaggaactt cattagtaga aggaaccgcg
     2461 tatgaaataa cttggtagcc ctttttgcga gctaaccgcc taaactcttt aacttgagat
     2521 aaggaattat cctcattact tgcatataaa attccaactg ttttgacatg tggtgtcagc
     2581 tttttcatta aatcaattgt ctgtttaaca ggcactttat tagatagacc agttacatta
     2641 gcttcaggtt gatccaattg catcactaat ctagatccta ctggatcaga tactgctgac
     2701 atgacaactg ggatatcctt gctggtggct gctaagcctt gcgccgccgg ggttgcgata
     2761 ccaatcacga tatcacttcc tgattgcact aattgcctac tcattgtttg gattttactc
     2821 tgatccccct cagcattcat aaccttaatc actacatttt gtttttgagg catctgcttt
     2881 ttgagttgat cttcaatacc tcgcttaata tcatcaagag cctcatgagt aacgaattgt
     2941 aagatgccaa ttgtaatgtt ttgttggtta gccaaatcac ggttttcctt tgatactcct
     3001 tttgataata gagagcctat cactattaca gttaaaacaa ggagggtagc tattaaactc
     3061 ttgtttttca tctgaattcc tcacatttca tgtcaatctc tttaaaacgt tgatgatgag
     3121 aatacttctc aaaagaaaaa gcacttagta atgattacta ggcgctcttg tgaaatccaa
     3181 tgtcagcgca tagatatctt tttagaagta ctctaaaagt cgtatctatg ccaattcata
     3241 aacacaactt atctatgcca gctttgccaa tttgctaagt gttgtgtttt taccatcatt
     3301 gacttccttt ctcgtttttt taacattata acctaaatca aaaaaattgc aagctctttc
     3361 gtccatattt ttagtcaagt atttgtggta taatgaagag attagaattc agaaaggaga
     3421 aaccatgtct tttgacggct ttttcttaca ccatttaacc aacgaattaa aagagaactt
     3481 gctttacggt cgtatccaaa aggtcaatca accctttgaa cgggaacttg tcttaaccat
     3541 tcgtaaccat cgcaagaatt ataaattgct attgtctgcc catcctgttt ttggaagggt
     3601 acaaatcacc caagcagact ttcaaaatcc tcaggtacct aataccttta ccatgattat
     3661 gcgtaaatac ctccagggtg cagtcattga gcagttagaa cagattgata atgaccgcat
     3721 tatcgaaatc aaggtatcta ataaaaatga aatcggagat gctattcagg caaccctaat
     3781 cattgaaatc atggggaagc acagtaatat catcttggtg gaccgtgcag aaaataaaat
     3841 catcgaatcc attaaacatg ttggtttttc acaaaactct taccgcacca ttttacctgg
     3901 ctctacctac attgagcctc ctaaaacagc tgctgttaat ccttttacaa ttacagatgt
     3961 gcctctattt gaaatcctcc aaacacaaga actaacagtt aaaagcttgc aacagcattt
     4021 tcaaggtttg gggcgagaca ccgcaaaaga gttggccgag cttctgacca cagacaaatt
     4081 aaaacggttc cgtgagtttt ttgctagacc tactcaggca aatctgacca cagcttcttt
     4141 tgcgcctgtt cttttctcag atagtcatgc gacgtttgag actttgtctg acatgcttga
     4201 ccacttttat caagacaagg ctgagcgtga ccgtatcaat cagcaagcca gtgatttgat
     4261 ccaccgtgtg caaactgaac tggacaaaaa tcgcaacaag ctaagtaagc aagaagctga
     4321 gctgctagcc actgaaaatg ctgagttgtt ccgtcaaaaa ggagaattat tgaccaccta
     4381 cctcagtctg gtcccaaaca accaagactc tgtgatttta gacaattatt atacagggga
     4441 aaaaattgag attgccttag acaaggctct gacaccaaat caaaatgctc aacgttattt
     4501 taaaaaatac caaaagctaa aagaagctgt caaacactta gctggattga ttgccgatac
     4561 caagcaaagt attacttact ttgagagcgt agactacaat ttatctcaag caagtatcga
     4621 cgacatcgaa gatattcgcg aagaattata tcaggctggc tttttgaaaa gtcgccaaag
     4681 agacaaacgc cataaacgta aaaagcctga gcagtacctg gcttcagatg gaacaaccat
     4741 tctcatggtg ggacgcaata acttgcaaaa tgaagaactc acctttaaaa tggctaaaaa
     4801 aggagaactc tggttccatg ctaaggatat ccctggaagt catgtcatca tcaaagacaa
     4861 tcttgaccca agtgacgagg ttaaaactga tgctgccgaa ctagctgctt attattcgaa
     4921 agctaggtta tcaaatctcg ttcaggtcga tatgattgaa gctaaaaaat tacacaaacc
     4981 tagtggcgcc aagccaggat ttgtgactta tactggtcaa aaaactttac gggttactcc
     5041 tgaccaagcc aaaattctct ctatgaaatt atcctgataa gcaactaaaa aacagctctc
     5101 ctaggaaagt tatttcccct aggagaactg tttttttatt ctgattgttg gtgcttgata
     5161 tggtcaagaa agtcttgcat attcacatca tcaggcactt gtctgaggta agcggtagcc
     5221 atttggatag ccttgtgaaa ctggccaaac tcccttaata aataggcata atcctgtaaa
     5281 aactctggat tttctgccaa atcagccgaa atctcattat aaagagccaa ggcaacttct
     5341 tcttgttcca aggcgtggta agcctttgca atggtccatt tggttaagac attatcaatc
     5401 gtctcacgat taagagcaat aacctcctca aaacgctcgg catcaaaata aagggtcact
     5461 aaacgcatga gaatctcttc gtcatcaaca gctacttcct ttgcttgaag caggtaattt
     5521 tcagcattct gcctatcgtg taattcataa gaaagctgcg atgctagtaa taataattga
     5581 ctgtcaaatg catttttacg taggccctgt tgaaccaagc gcaaagcttc tgacgtctta
     5641 tgctcttcat gaagactcaa agcataacca tattcataac ctggataatc tggattgatg
     5701 gtttccaact gtttaaagta aagattggct ttttgataat tttcttggtc atacatgagg
     5761 gtcgccaatt caaaaacagt ttcatcttcg tattcaatgg ccacggcctt ttccaagaat
     5821 tcgatggctg cctcaaattt ccctaagcta gcataggctc gtccaatgcg ttgataagtg
     5881 gaaatacctg tcaattcaag gatttgacga ttgtctaact gtgcatagta atcaatagct
     5941 tctttaaaat gctgcaagga catgtcaatt tctgccaaac caaaaatgac caatggctct
     6001 gggctgatgc ccactgcttg aagcaatttt tcacgcgcca cctctgtcag tccttccatg
     6061 tcatagaggt cagccattac taagagagct gacaaataat tggggctatc ttttgaaacc
     6121 ttatccaaat acaagaaagc ttcttcaatg gcgtcgtctt ctgctgcaat ctgagctaaa
     6181 tttatattga gttctgggta atcatcagct aactgcaaat aaatacgctt ggcatgtggc
     6241 aaaaaaccta tactttctaa gtattctcct aaggcgatta aactatctgc atcatcttct
     6301 tttaaagctt tttggaaata tttttcagcg tgcgctaggt cttgctgatc caaggaagca
     6361 atcatttttt cactatttaa catggtcctt aacctcctca atcaccaata cttcttcgtc
     6421 atacaaaccg ctaacttttt tgtaccagtc aaataattct ttaatcacaa ctttgacaga
     6481 agcgtagatt gggatgacaa ggaaaacacc ccagacacca aacatagagc ctgcagtcaa
     6541 taacaagaac ataatggtaa taggatgaat gctcagctta tttcccaaaa caagcggtgc
     6601 tacaaaacgc ccttcgatgg tttgctcaat cataaagata acaagcacct taaccaacat
     6661 aaatgggcct tgtaccatag ccataatcac aacaggtatc atggcaagga aacttcctaa
     6721 gtaaggtatc atgttaagaa agccagcaat aatcccaaaa gtgatggcat atttcagtcc
     6781 cacaaggcta aacatgatag aaaacataaa gccgacaaca attgcaaccg taacctgccc
     6841 ttgcacatag cctgataatt gcttgttaat atctcccaag actcgaacca taggcacccg
     6901 taatttgaga ggtaagacat tcacaaggcc atttttcatg tggctactgt ctcgtaaaaa
     6961 ataaaagaga ataaagggcg aaataataat agccacggta atccgagcaa tggcaccagc
     7021 aaaattacca gcccagtcaa tagcattttt tgaaaaactt tgcgcgtaat ccaaagcctt
     7081 ttgacttgta tgggtaagca tgtcttggag ttggggctta tagctgacta accattcatt
     7141 ttcaagaagt ttattggctt cttcattgac cttgcccacg tatttgggca gatcctcaat
     7201 aaaactggta agttgggtct gtaccatggg aacaaagcct gaaatcgccc agacaaaaag
     7261 taaggtaatc aaaccaaaaa caataaaaat agaggtggta cgattcgggc ccaagtgatt
     7321 aataaggtca actaagggtt tggtcagata atacagaatg gtcgaaataa ccaagggcaa
     7381 catgatgacc gcaaaaaaag aaatcactgg cataaataaa aaagagattt tagtaaaaac
     7441 aaaaatcgtt aaaaaggcta aaagtgttat tactaaagcc atggtagctt gattatttaa
     7501 aaaccatttg taaaataagc tatctgttct agacttttca ggtattaagg gcattaagat
     7561 agggttcctt tctttgggaa aatgataggt tttactggta acctgggtaa atcaataaaa
     7621 ggtcacagat ttatccatga gttggttgtt ttggtcatag gtaaatttgg cagagaaaaa
     7681 agaacggtct tctaaaatcc atttaaaaat gtcataatca ccttcccaag ttggcttttc
     7741 caacacttga tcgtaaggta cccattccaa ggttccttct cgtgactctt catctgaaat
     7801 gaggtctcct tcaaatcctg ttactttaaa aacataggta taccagtcat gaccaggggt
     7861 aaattctgga aaagtaatga ttcctttaaa ggccatctct gtaacagtca aatgggtttc
     7921 ctctaaaatc tcacgacggg cacactcatc tggggtctca ccagcctcga gcttaccccc
     7981 aactgaaatc cacttgcctt tgtggacatc attttctttt ttattgcggt gtaataatag
     8041 caaagaatcg ccattatcaa tgtaacaaat ggttgctaat tgagtcatct atctctttcc
     8101 tttccatctt tgtttctatt ataccaatct ctagaaaata tgctatcatt ttatgagtca
     8161 aagtgtgaat acttagtcac gctcaaaacc ttctaaagat gccttaaaaa agtgtagata
     8221 agagcctaca atgaaaaaca tcaatttaaa ctatcaaaag aaccttgtca tatcaattat
     8281 cgttgatatg acaaggttct ttaatgtttt atttaatcac ttcttgagtt ttagcatact
     8341 tggcttctac agcatctttt tctgctttcc accatgtctc attttctgtg taccacttaa
     8401 tagtttcttc caaaccttct gaaaagtttg taaattgtgg ttcccagccg agttcttcac
     8461 gcaattttgt agaatcaata gcgtaacgaa gatcgtgacc agcacggtca gttacgtgat
     8521 cataagcgtc ttttggttga cccattttct caaggataag ctcaagaact tccttgttgt
     8581 ttttctcgcc gtcggcacca ataaggtatg tttcaccgat acgaccctta gtcaaaatag
     8641 cccatactcc tgtagaatga tcattagtat gaatccagtc acggacgttt ttaccttcac
     8701 cataaagttt tggtttgatt cctgccaaga tatttgtaat ttgacgtgga atgaattttt
     8761 cgatgtgttg gtatggtcca tagttatttg aacagttcga aatggtcgct ttcacaccga
     8821 aggaacgtac ccatgcctta acgataaggt cagaagctgc cttagttgat gagtaaggtg
     8881 atgatggatt gtattttgtt tcagcagtga atttttcacc tggtccttca ccctgtcctg
     8941 gaaggtcttc acgaagtgga agatctccat aaacttcatc agttgacacg tggtggaaac
     9001 ggatatcgta tttacgagct gcttcaagca aagtgtaagt tccgataaag tttgtatgga
     9061 taaatggact tggatcttcc aatgagttat cgttgtggct ctcagccgca tagtgaacaa
     9121 taacatccgt tttggcagcc aatttatcta ccaattcagc gtcagcgata tcaccaacaa
     9181 ctaactcaac acgatcacca agaatagctt caatgttagc acgattacct gcatatgtca
     9241 atttatcaag gacagttaca tgaacatctg ggtggttatt gtagacatag tgcacaaagt
     9301 tagatccgat gaaaccagct ccaccagtta cgataatatt tttatacata agatataaag
     9361 ggacctttcg tttccgaaaa aatctattaa aagtaatgac tctaacaaag acgttttagg
     9421 cctaagaaaa catcgctttc taagatttaa gtcccatgtt cagctcaaag agagaaactg
     9481 aactttcctt tcatcatttt tagttgttac ttgttacctg aagtagagaa gaataactcc
     9541 cctcatatcc acctcaaatg attaatccca atcatctgag tatgttgttt ccctataggt
     9601 cttttggttt cagtggtttg acatcactaa gaagaggatg gtttttatct gcttcagaaa
     9661 cttctgcagc tgctagattt tcccaagtaa tcccaagact tgggtcagca tagtttacaa
     9721 aagcatactt aggtttcaag tcaagagccc agtagtcatt gacaagataa ctgtaagaga
     9781 cagtctctga aagaacttga aagccattag caacccctct aggaacaaac attccttttg
     9841 aagcatcaat cactgtctgg tagacgtttc caaaagtctc tccctcacga agatcaaccc
     9901 aagctcctaa aaccttgcca tcatcagcaa ctgagatgta tttatcccaa ggttcagcat
     9961 gaagtccacg cagcacatgc tgacgtgaaa aagaaacgtt gttttgtagt tttccttcct
    10021 caaaaaaacg ttctggaaag ccaattggca acattttttc tttttggaaa ttttctttaa
    10081 accagccacg attatcccca cgaacaggaa tatcaaactc tagtaagcct gggatttctt
    10141 tgatttctcg gcaagccaat ggtttgtcaa aaaaagtttc tgtcattaag cttctccaat
    10201 caaacgaagc aagtattgcc cgtattcgtt tttctttaaa gattgcgcca atttatggac
    10261 atcttcttta ctgatatagc ccatgcgata ggcaatttct tccagatttg ccacttgagc
    10321 gttttgcaag cgttgaacag tttcaatata ttgagccgct tcaagtagac tttcatgcgt
    10381 tccagtgtct aaccatgcaa aaccacgccc catcaattca acggagaggt caccacgttc
    10441 caagtaagcc ttgttgacgt ctgtaatttc caactcacca cgcgcgcttg gtttaatgtt
    10501 tttagcaatc tctaccacgt cattgtcata gaaataaagt ccagtcactg caaagtgaga
    10561 cttaggcact tctggttttt cttcgataga gatagcattc atgttctcat caaattccac
    10621 cactccaaag cgctcagggt ctttcacttg ataaccaaaa acggtggctc ctttttcttt
    10681 ggcagctgcc ttttgaagca ttttagtgag gccattaccg tggtaaatat tatctcctaa
    10741 aataagagca acacggtcat caccgataaa ctcctctcca ataatgaaag cttgtgctaa
    10801 accatctggg cttggttgtt ccttatagga taagctaatg ccaaattctg acccgtctcc
    10861 tagcaattct tcgaaacgag gaagatcttg gggagttgaa atgattaaaa catctttaat
    10921 ccctgccaac atcaaggttg acaatgggta ataaatcatt ggtttgtcat aaatgggcat
    10981 caactgttta gatgcggcac gggtcagtgg atacaagcgt gtccctgaac ctcctgcaag
    11041 aataatacct ttcatagtag tgctcctatt cttctatata ccctatcatt ctatcatttt
    11101 ttgaaagcag tgtcacgctt taccagtaga ccgcaaaagg taaggctcag gagaatagtc
    11161 gctaggcgtc aaaagtcctt cgtgtcctag caataattga gctaattcat agccaatcaa
    11221 aggtccaact gttaatcccg atgaccctaa accactagct gtataaaggt tcttcaatcc
    11281 tgaaacctga ccataaaaag gagaataatc actggtataa gctcttattc ctacacgaca
    11341 cgttttttga gtagcttctt ttaataacgg caaataagta agagcttgca tttcaagttt
    11401 ttctaaaacc tgccaatcag gctccaaatc ataaccttta tcattttcgt gactcgtacc
    11461 aacagaaatc ttaccttggt taaaaggaat aagatctatt tcaccttctg gcataacaac
    11521 tggataagtg tcgctgatga tgtgatgaac gtcataatcc aagagttgtc ccttttgtgg
    11581 tcgcacatca acctgatagc ctaaaggcct caataagtca ggtagccatg ctcctgctgc
    11641 cagaatgacc tgatcaaaat aatgaccagc aatctcataa ccacttcctt gctgtttcag
    11701 agtgactttt tggcgaataa ctggataacc actagccttg agtaatgtct cacataaagc
    11761 ggctccctcc actctagcag ctcctgaagc gtacagacag ttatcaaagc caatcaatcc
    11821 tttaaaatca ttccccagtt ctttacgatt tttaacggct aactcaccaa taatcggtga
    11881 ttctaccttt cttgctaacg ctaattcata aagatctctt agtttttctt cctgcttttt
    11941 taaaacatag atgccatttt gctgataaaa atctgttgca aaaccatctt ctttgaggtc
    12001 attgattaat tgctgataaa agtccgctcc taaacgagcc atgcggtacc aaactttatt
    12061 gcgacgcttt gaaaaccaag gactaataat accagcagct gccttagtgg cttgtccttg
    12121 accatggtca aaaatggtaa cttctttttg accactttgt tgtaaataat aagcggcggt
    12181 tgatcctaca atccccgccc caataatggc tattttcatt cctggtatcc ttttatctta
    12241 ttttaagacc ttaacagcct ataaatggct aaatggattg gtcgaggctt tgcttgaaat
    12301 aatgctgaca tcccaaccgt tctcttcttt ccacccttgg agtttctcct ttaatttctc
    12361 cgtaaaaagc acctcaatat gatgccccgg gtcaaccgca aatagtcctt ctgtcagcat
    12421 ctcctgtgct gtatggtaat agatatcccc tgtaatataa acgtctgcgc ctttttgcac
    12481 agcatcctga taaaattcac caccacttcc gccacagata gcaatctttg aaatcaaagg
    12541 gttttcctta tcgtaacgga taagtcgcac ggtatctaaa tcaaacaccc ttttgacctt
    12601 acttgctaac tcttctaacg cttgttcttt aactgttcca atacgaccaa tgccaaagcc
    12661 ttctttggtt tcagacaagt aagttgcttc cttgatttct agcaggtcac aaaaccaatc
    12721 atttagccca cctggtacaa tgtcaatatt ggtatggctc acatagacgg aaatgtcatg
    12781 cttgaccaaa tctagaagga tatcacgctg aggggatgaa accagatctt taagcggttt
    12841 aaagatggga gcatgcttag ttataatgag atcaacttca tttttgatgg cttctgctac
    12901 tgttgactct cggatatcta aagtaatcat aaccttacga atgtctttat ccaatgaacc
    12961 catttgaaga cctttaacgt ctccttccat agataaatca agtgggcaaa aggcttcata
    13021 ggcatcaatt agggttttag ctttcatgaa caatcacctc ttttatttgt tgtatttttg
    13081 tcaagagaag ctgacgctct tgagtttttt cttctgggat gcaggacaag gcataagcta
    13141 acttatccat ttctcgttgc cacttctctt taaaaacgac tgatttttcc tgagaaaggt
    13201 atggaccaaa acgcaattct gtcgcggata aggccttttc accatgctca gcaacgatga
    13261 tttcataata tttgtcattt tcagccatga tggtttctgc aacaatttta aaagcgttaa
    13321 ccgataacca agcccgtaaa tcatcctcac gattgttggg ttgtaaaacc agacgttcaa
    13381 tgccctgcaa tttttcctta cctgcctcta aaatatcagc aatcaaacgg ccacccatgc
    13441 cacaaatggt aatggctgtc acatcatcag cttcttcaaa ggctgcaagg ccattggcta
    13501 agcgcacctg aatatgctcg gcaaggccag actgtgtgac atttttaaga gcagattcgt
    13561 agggacccct aaccacttcg ccagcaatgg ctgctgaaat ctgattagtt tctaccaaaa
    13621 atatgggaag gtaggcatga tcactgccaa catctaataa tttgacacct tttggaacat
    13681 aggccgcaac ttgggccaaa cggtttgata attgactatc catcttgatt tctttctaaa
    13741 acgtaatggt tctattatag caaaattacc tccataaaaa aagaaaacca aaggctaggc
    13801 tttcgatttt ccataagtat cttgatagta cttgcagtaa gactgaacgg gacaaatctc
    13861 acattttggt tttttggcta aacaatggta gcgtccaaaa aaaatcaatc gatggtgagt
    13921 aataatccaa tctttctttg gaattttagc catcaaatct gcttcaatct gcttgacatc
    13981 ggcatctggc gatgaaatat tgagcctctt tgagactcta gccacatgag tatcaaccgc
    14041 aatagctgga acaccataaa cctctgccag caccacattg gctgtttttc ggccaacacc
    14101 cggtaaactt tcaagctctt tgtgggtttt tggcacttga cccttaaaat catcacgaat
    14161 agcctgagca gttttaatga tatttttggc cttattttta tagagtccaa tcgttctcag
    14221 agcattttca acatcagaaa gttcagcaaa agctaagtct tctatttctg gataagactg
    14281 ccatagtcca ggagttacct tattgacggc cttatctgtc gtttgagctg ataaaatcac
    14341 cgcaatcaac aattgaaaag gtgtttccca gtctaactct cccttagcct caggaaacat
    14401 ttgaccaatg atggtcagga cttttgctaa tcttgctttt ccaattctca tgaatcactc
    14461 cataaattca tcgcagatag aaaatcctct gatatcgtca cttgagaaag atcttcgcct
    14521 tctctaacac gtctacgttc ttctacttgt cgaagattaa caataccttc ttttcgccaa
    14581 ttacgtaaga tagcctggat atatttccaa tttgttttgc cgttgaagac agcttctttt
    14641 aaagcttctc gtatcaaatc aggatctgtt ttatcatcac gaagcgtttt ttcaagatct
    14701 tctaactcaa aaggactcaa gaatcgtcct agttcacgtt caaattcatc aactaatcgt
    14761 ttgaaatgat ttggtgtttc ttgtttgtca atttcagttg ccgtttgact gacaaacaat
    14821 tgatctaact tggctaacac aggactcgca tcaaaaataa tttcaatttc tccagtaagt
    14881 tcaattgtcc gcatatctaa aagcccttga ttagtcaaag atgaaatgat tttattaata
    14941 tcagcaactg attttccaag cgcatgagca atttgactgg gtgctaagtc gtctcgcttt
    15001 gtcgtatttt gaagatagaa aaactgccag accaaaaaat catctgagct cttaaaaaga
    15061 tctttgtaat gaaaaagcaa ggcacttggg ataaccaaat tacctgactt ataatgttct
    15121 aaaaaactca taatccctca atcaaaaggc taaaatcgaa tctatagcct ttactacttt
    15181 aaatccccta atcagatgct gattaatgtg tttacccagg aaactgcatt aagactttat
    15241 agtcatagtt cctaatagca tggcgtccat ttaaaccttc taattcaata aggaaggcac
    15301 aaccagctac aataccacca agtttttcaa tcatttcaat agttgctttt actgtaccgc
    15361 cagtcgctag taaatcatcg acaatcaaaa cacgttgtcc aggcttaata gcatctgcat
    15421 gcatagttaa agtatcaaga ccatattctt tttcgtaatc ggcagagaca acatctcttg
    15481 gcagttttcc tggtttacga acgggagcaa aaccaattcc taactcaact gcaacaggac
    15541 aaccaatgat aaaaccacgc gcttcaggtc caacaaccat atcaatatct ttatcacaag
    15601 cgtactgtgc tatttcacga atagcatagc tatatgcttt accgtcagcc attaaaggtg
    15661 agatatctcg aaacgtaata ccagctttag ggtaatcttt gatcgatgca atgtaatttg
    15721 ttaaatccat agttaattct ttctagtggc aaattgccaa atataaaata ctcttcatta
    15781 tatcacgaaa catatttttc gtaaaataag acttctgaca ttattgttta tctgatactt
    15841 cattcgtaac tacctcaata actactgtca actgctttac ttattgatcg tttgatttca
    15901 ccaaataatc atacatctct ttcgggctag ccaaagccat gatttcttga aatttcacca
    15961 attcttttaa gtcttggtaa atgtggctct ctgaaatctc tcgtttttgc gcttgggggt
    16021 taaccgtcat cagcccatcg tcaatcgtca caaaagacaa ctcttcaaaa atttgaatca
    16081 acttaatcag taaaagtttt tctatgttta aatagtgact caactctgtc aatttatgtc
    16141 gtaaatcaaa ttcaggaaac tgatagatgg ttttgtagag cttggcaaac tgctctctgc
    16201 tgccaaatcc tgttaaataa taaggatgtt tcatctgatt tttaaaatag atggcgtcaa
    16261 aatccttgtg aacaaactgg ttgcgccagg ttttgaaatc ttcagggatg tcattaatca
    16321 gaatgactct ggcatttggg tcttcttcaa tagtcggaat accttcagga actttggctg
    16381 tttttgtcct taagtcaaga agttgcactc cgtcaacacg agcatctact aacatgaatt
    16441 ggagactcgt gttcccattc caatggttga cagataaggt aactgctaat tctaaaccag
    16501 tagcttgtcg gaactcttgc agttgacttc cttgaccaaa agccagtacg tcaaaggaag
    16561 ctttgccctg actgacttta aatttaagat ggctctggtc ttgccctatg gtacgcgctt
    16621 gactaaccct tatgtccttg acataaaaga ccggcttttg atgatccatc ccataagggg
    16681 ctaatttatc taaactcttt aaaatatcaa ggctaaggtc gtccaaagac agtctttcat
    16741 caatagttaa cgtatttttg gcagtctgat ctaagccacg ttctatcaca aactgacaaa
    16801 gaaagtctga aagagcttcc aagttgtcaa cgggcagggt cattcctgct gcaccagcat
    16861 gtcccccaaa ggctgtaaat aactcacgct tgccatttaa ggcttcaaaa atattaatag
    16921 cttctaaact tctggccgag ccttttgcaa agccattatc aatggtcaaa acgacgaccg
    16981 tttgtccaat agtttccatg atacgaccag cgacaatccc aagaacacca ggatgccagc
    17041 cagcttgtgc caagacttga acaggttttt gaggatcaac catagccatc gcttgatcaa
    17101 aaatgtcttg gactaaggcc ttacgctctt catttttttt cttaatcatc aaggcaatcg
    17161 cttgagcttc ttggtcatca aagcccgtca gtagctcaat ggctggatta gggtcatcta
    17221 agcgccctaa agcatttaat tgcggagcaa tctgaaagcc aatggcgtct tcattaaaat
    17281 gttccaaatc aataggagac aaggacatca actcctgcaa gcccactctt tcggtgtgtt
    17341 tgagcatggc cagaccattt ttgactaaaa cacggttttc acctgtcaag cttaccatat
    17401 cggcaatggt tccaatagct accaagtcta gacagtctgt tggtaaactt tctagcaaag
    17461 ctgttgccaa tttaaaggca acgccacagc cagctaagtg tttaaaggga taatcagcat
    17521 caggatgctc aggatgaatg atggcaaagg cttctggcaa ttcttcaggc aggctatgat
    17581 ggtcagttac aataacatca acttcctgtt cttgagcata tctaatcgct tcatgtccgg
    17641 ccacgccatt atcaaccgtg ataattaggg acacagcttc ctgctcaata aaatatttat
    17701 agacgctctg gttggggcca tagccatctg taaagcggtt gggaagataa accaaaggct
    17761 ctgctcccat catgtctagg gtttctttga caatagaagc cgacgtcatg ccatcagcat
    17821 catagtcgcc gtaaatgaga attcgttcgc cctcttcaat agcttgacga attcttggca
    17881 cagcttttgc catgtcatgt agcaagtaag gatcatgcag ttgagacaag tccgctgtta
    17941 aaaactcatc taaggcttct tcagtcctta tccctcgatc ataaatcaac tgagcggcgg
    18001 tctgggttag accttttgtc tttgctagct taaagaagcc atcatctggc ttcttgtctt
    18061 ttattttcca gctatatttg gatttaatca tttataatta aatacctttc ttgcaagata
    18121 atcagataat ttagggaaaa gggtgtaaaa ttgatgggtc accgctaaac taaagggcaa
    18181 attcaattct cgtttatttt tcccgataat agaaaccaaa cgcttagcca cttgatttgg
    18241 ttggagagta aatttaccaa cgctttccaa ataatgtcca gacgggtcag cttggtcaaa
    18301 aaacttggtg gcaatgggac ctggattcac ggtggtcacg taaacccctt tatccgctaa
    18361 ttctaagcga agggcattgg aaaatccgat aagggcaaac ttggtggctg aataaatgct
    18421 cgatttggct gacgcaatca agcctgccat ggacacaata ttaataaggt gaccttgccc
    18481 ctgctctgcc attttctgac caatcaagca agcaaagtga atgctcgcta gggtgttaac
    18541 ctgaaacata tcagctattt cttgggcaga aaactcttca aagcctttga aagctccgta
    18601 gccagcatta ttaatcaaga catcaatacg gccatagcgc tggtaaatct gggcgaccat
    18661 tttctcaatg gctactggat tggtaatatc caactcgagg cattctttgt tgtcaatatg
    18721 ctgataacag tgttctaggc gttctttgtt acgtcctaat aaaatcaagc tgtcttcctt
    18781 gggtaactgc ttaacaattg cctgagccag tcctccagaa gctcccgtga taacaatgat
    18841 tctttgtgcc attaaataat cacttcctct aaatcttgta ccattttaac attttcaaat
    18901 atagtggcgg catctttttc catctggcga caatcacgcc ctaaaaagcg agctgataca
    18961 tgattgagca agaggcgttt tgcgcctgct tcatgagcga tttgtgctgc ctgcatgttg
    19021 gtagaatgcc cgtgatttct cgcaatccgc tcgtcaccct taccataggt ggattcatga
    19081 accaaaacat ctgcatcttt agcgagttta acactggcag acgttttgcg cgtatcgccg
    19141 ataatggtga tgattttgcc ttttttaggg gcagaaatat aatctttggc acaaatcagg
    19201 cggccgtctt ccaactcaac gtcttgacca tttttaattt tgccaaagag tggtccaaaa
    19261 ggaacacccg ctgcttttaa ggcttctgcg tctagggttc cttctaagtc tttttgaact
    19321 actcgataac ccatgcaaaa aatggtatgc gccagacgct ctgcatagac ctcaaactta
    19381 tctgtttcca ttattttacc taatgatttg tcatcaaatt catgaaaatg aatctgataa
    19441 ggtacacgcg ctccagaaac ttttagacta gttaacacgt aagttttaat gccaattggt
    19501 ccataaatat caagatctgt ctgttcttca ctagcttgaa aagaccgact tgataaaaat
    19561 cctggtaatc caaaaatgtg gtctccatgc aaatgagtaa tgaaaatctt tcttattttt
    19621 cgtggcttaa tcgtcgtttc taaaatttgt ctttgcgttc cttcaccgca atcaaacatc
    19681 cagacttcat tgatttcgtc tagtaatttc aaggcaagac ttgacacatt gcgctgcttg
    19741 gctggttgac cagctccagt tcctaaaaat tgtaattcca ttcaatctat tctttctatt
    19801 gggtgatgta aatcataaat tctcgttggg caaaatcata atacttttga ccagaaaatg
    19861 tttggctaag agcccataac tcctctacat taaacccctt aagcatggtg ataccgtttg
    19921 ccagacggta aatcttcgac aagagtgtgt catcaggtgt aatgtcttca cattctcctt
    19981 gctcaaactg cttagcctgc attttaagct ggcctttgtc ctcataaacc atatattgtg
    20041 ggaaaatttg tgttaattca aagaagagtt cgggtttctt aggctctgct ttttcagaaa
    20101 ataccaatgc aacttcttgg tcattttggt aagcaaaacc ataagctttt ccagacaaat
    20161 tgaggcgtac aaagggcttt tcttcctcaa aagatggttg gtcagtaaaa agccccaaag
    20221 ccttagaaag attaaaataa taatcagttg cagcttgcgg tgactgtttc tggtagattt
    20281 cagcaaagta ggcattaata acacttggtg gtggtgtgat aaaagctagt ttttgctggt
    20341 ctgtcaaact ggctaacaga tggtttaggt agttggtatc cagactagta aatccaccat
    20401 aggtttttgc taaatcaata taattattca taaaaatcgt caagtctcca ttgctgtttt
    20461 ggggaaatgt agcccgaaat atcctctatt tcttggtcaa acgtgtagtg gtctaaaaga
    20521 gcaactcgat tcaaatcata tagcttgtac gccttgtctt gatgcacttt gattctaaaa
    20581 ggaacaaact ggtctcgaat ttggtcaatg attaaacgtc tcaagagaat tttgctatcc
    20641 tttgaacggg ctgaaatcct gatatttgga aaagcagtag ctgtgaattg ttctgctata
    20701 tccaccttgt tataaatagc taaacgcgga atattaagca tgtctagctc ttttagaagg
    20761 tttaaaacca ctttttcttg ctcactatga ttgggatcac tcgcatcaat cacatgtaac
    20821 agcaaatcca catatttgct ttcttctagg gttgatttaa aagcagccac taattccgtt
    20881 ggcaagtctt gaataaagcc tacggtgtct gttaaggttg cttgaaattg attttctaaa
    20941 tagagttgct ttgtagttgc atctaaggta gcaaataatt cattggcttc atagtggctg
    21001 tcatctgtca acaagttcat aatggttgac ttgccagcat tggtgtagcc aatcaagcca
    21061 attttaaagg tatctgaacc cacacgacga tctctaattg tttgacgatt tttctctacc
    21121 tgagttaatt ggcgttcaat atcagcaatc tgatgacgaa tcgaacggcg atttaactct
    21181 agttggcttt cacctggtcc acggctccca ataccacctg cttgacgact taacatgatg
    21241 ccctgtccaa ccaaacgagg taacatatat ttcaattggg caaggtgtac ttgtaatttg
    21301 ccctcatggc ttctggcacg catggcaaaa atatctaaga ttaactgcat acggtcaatg
    21361 acttttacct ctaaaacagc ttctagatta gcattttgcc tagcagtcaa ccgattgttc
    21421 acaataactg catcaatctc atcagcttcc acaatcgcct taatctcatc cagtttccct
    21481 gagccgataa aggttttgct gtcgtaacgt tctcgttttt ggctgaaact tgccataact
    21541 ttgacaccag ctgttttggc aagattagct aattctgtca tggacatgtc aaaatgttct
    21601 gttgtctgaa gctcaactcc taaaagaatc actctttctt gctgacgctt tgtctcaatc
    21661 atcaccttta ccaatcctcc aaattccgta aattctatta taacatatct tcaacagatt
    21721 ctgctaattt tgcgtcatga cttctctttc tgaccaagaa aatccctgac cctatcatgt
    21781 actacctgtg ggtaatcagg agccgttatg gcagtgaagc taacagccat tcgattgcgg
    21841 aaccaagtta gctgtcgctt ggcaaaacgt ctcgtgtttt gttttaattg atcactagct
    21901 tctgccaaag tcatttcacc tacaaaatag gggaataatt ccttataacc tatgccacga
    21961 ctagcctgaa cagtcgggta atgctcatat aaccattttg cttcttccaa taagccgttt
    22021 tcaatcatac gattcacgcg ctgattgata cggtcataga tgacttggcg gtcatcattc
    22081 aagccgataa taagcggctc ataagccgtc tcggcattct ctaattcatc agcaaactga
    22141 gccaattcaa gggctcggat cgcccgtctg cgattcacct gctcaatggt aatgttattg
    22201 acttgcaagc gttcatacaa gtcgtgatcg tccaattgct ccaactcatt ccgataggct
    22261 tttaccgcct cttgatcaac ttgacctcct agatgataac cttcgagtaa actttgtaag
    22321 taaagaccag ttccacctac aataattggt aatttcccac gactaacaat atctgaaata
    22381 gatttttgag catcttgaac aaaatcgtag gccgaataag actccgtcac ctcacgaata
    22441 tcaattaagt gatgaaccgc tgcttcttgc tcttcttgag tggccttggc tgttccaata
    22501 tccaactgtc gataaacttg ctggctatct cctgaaataa tttctccatt aaaagccttg
    22561 gctaaactaa tcccaagtgc tgtttttcca accgctgtcg gaccaacaat cacaactatt
    22621 tttatttttg tcattttctt gtctttctat tagaaaagcg tgtccaaaaa cgccttttac
    22681 ttgaaaatta gcttattttt cgctaccata tattataaca taagattaag gaccactgag
    22741 gtccttcact agaaatggag aataatcatg gttaagaaat atcaatttgt taaaggtctt
    22801 gctactggcg tcctagcaac tgctgctact gttgctggtg ctgtctttgc tgtaaaaaaa
    22861 acaatcattg accctgaaga agaaaaagct gctttcattg aagaaaaccg caaaaaagct
    22921 gcgcgtcgtc gtgtagctcg ctaacgtgac aatggatcaa tttaaaagag actagcacat
    22981 taaagtgccg gcctcttttt tagtaatctc gataactagt tagtagtaac tgtctcttga
    23041 tgagccaaga tgttagctgc tttacttatt ttgaaataga aatctcaggt aagccccata
    23101 aacataagtg actaaagctg tcgccaacaa tacctctcct agcaaaagaa cctgccaacc
    23161 taaaccttgc caacctaaaa aagataaggt catttttaag gaagtggcac taatcacaaa
    23221 cggaaaggta aaagctgaaa aacctgggtt aaagggacga ttgagtaagc gaggaagctg
    23281 tacaaccaca aaagcatata acagttgtga gctgacgaga agaaagataa ccattcctac
    23341 ttgtggtcta ggaaaggttg ctaaataaga cgctgaaagt aaggacagag gggcacaaaa
    23401 cgttgaaata ttgggcatta ctgcttgacc tagaccaatc ccataagtct ttttggccat
    23461 aaaaggtaaa atcacagcag ttaagagaag acaaacccaa aaaatcacct gtcctaataa
    23521 aaactgccta ctagcaggtg ctgttaatgc cgccattgca attccaacaa aaagcacgga
    23581 ccaggaagga aaaacgttat cccatgaaaa agaaaagaca aaacgatact ggtaataagc
    23641 aatcaggaca agatttccca aaaagaatag ccaccaagtg agaaagccta accaacaccc
    23701 tcctgtcact ttgagaaaga gtgaagacaa caacatccct gtcataaaaa aagttggaaa
    23761 aacagaggca attagaggtt gtcgtaactg cattttggta tcgttaaggt tcctaaccat
    23821 gccaacaagc aagataccat agataaaaag agctgccaga attcccaaat aattaaaaat
    23881 cgaaacataa gtagccaaca aattgccaaa tgacaacgtt cctaatgcca atcctgacat
    23941 gaccaatggt ggggttttaa ggtgtttcat aagtgtcctt ttctgcctat taacagctat
    24001 ttttagtgac ataatcttgt ttattttatc acatttcgag catttttgac accacccgcg
    24061 aaagaaaatt taaggctctt gccattgttt ttttacattc tcgcaaaact aggaaactgc
    24121 ttaaaaagct aaggagtgac cactcttctc tagaaaaatg aaagagtaga gaagacttgg
    24181 tctgatcttt acttcttctt tttgatttag tgagctgcat taagcacttg ttgaacagct
    24241 gaatcttcca ccatttttgc cataaaagct gccagatgcg gataattctc gtaagatttt
    24301 ggtgtttttt gagaccatag cgccatggcg taagcataag catctgcaat ggtttgttga
    24361 tctcgataaa catgcccact ctccccaata agactatcta aatgcgtcat agcaatatcc
    24421 atccgcttgt aagaagcttg tttgactttt tcaagcgctt gattgtcttg agaaatagtg
    24481 tagcgatgag ggttgatcat tggcctaaaa acaaggggaa aatcacctgt taagaagtcc
    24541 atgatttcgt tgaaccgact ttctgccaaa agattatctt ggggaatgag ctgagatttc
    24601 agggtttgtt tcgctataaa gggcaagata atacctgcct gtgtgacaat ttgaccatca
    24661 tcaagctgta aagcttaaac cattcccaaa ggattgatgg taaggcagtc ttcagaatcc
    24721 agttttacct tctctatctc gtaatacaga aactcacaat tcttttgaaa aggtgctaga
    24781 cagagttggt gttgacgtct tcgctgttga tggctctgca tgacaaaatg agcttggtgt
    24841 ccacgttcac ttgtatcttg ttgcaaagtc tttgcaattt ggtctcatca tctgtatcac
    24901 aaaaaacaaa ccagtttcct gatttgtttt gagatattag gcacctacaa attctggcaa
    24961 ggattctcca atagcttcta aacgttctgc ccattcttga cgtgataaac cattttcttg
    25021 cacatagcga ttacgttcat gtgcacgaca ttcaggtgag catcctcgaa catactttgt
    25081 ttcgttttct tctgaagcaa aaatttgttt gttacaaaac ggatttgcac aattgacata
    25141 acgttcacaa ggtgttccat caaaataatc tttactaatg acagttggat taacatgatt
    25201 aattggcacc gagatacgat catcaaaaac atacatcgca ccatcccaaa gttcaccttg
    25261 aacttccgga tcttttccat atgttgcaat accaccgtgt aattgtccaa catctttaaa
    25321 gccttctcga accatccaac ccgagaattt ctcacagcga acaccacccg tacagtacac
    25381 aacaacacgt ttttccataa acttatcttt gttgtcacgt acccattgtg gtaactcacg
    25441 gaaattgcga atatcaggac gaattgctcc acggaagtga cctaagtcat actcataatc
    25501 attacgcgta tctaaaacaa cagtatcttc atcaagcaag gcttctttaa attgtttagg
    25561 atttaaatac tcacctgttg tttccaaagg attaatatca ctatcaaagt tattgtcttc
    25621 taacccaagg tgcacgatct ctttcttata acgaacaaac attttacgga aagcttgttg
    25681 attttcctcg tcaatcttga accaaagatc agcaaaacgc tcatcgctgt ggacccaatc
    25741 catatacttc tgagttgttt cataatctcc agaaacagtt ccattaatcc cctcatccgc
    25801 aatcaaaata cgacctttaa gcccaataga tttacaaaat tctagatgtt tcgcagcgta
    25861 ctcttgcgca ttttcaattg aaacatattt ataatagagt aaaactctga ttttttctga
    25921 cattttttct ccttcattgt tattcagtta cttcctatta tatctaggaa aaacaagtct
    25981 aggcaagtca tttgtttgtc tttttttcac aaaatagatc tcaatttatt tttgatgaga
    26041 tgagatgcaa cccattactc ctttaagcaa atcattagaa gctttattta gaaaatgcta
    26101 agataaaaca aggaggccaa aatgacttat gaactttgtt tagaatatgg gacttatccg
    26161 ttgtcacgtg ttgatgctta ctggggagaa gatcaaaatc ccccaacatt cattcaagaa
    26221 gatcgactgc tttgccataa actagaaact atgaatcacc tgttccatga tttatttgta
    26281 actattgaat cacaattcca ttatgttggt tttaacatgc ctgaaaaaag agcgcagatt
    26341 cggatactat atcaagaagt agctactata ttaaaatcca aatataagga ttatccaatt
    26401 aagattgaga cgtttcttct ttaaaaatct aatactaaaa aactaactgt gcttagacag
    26461 atgacacagc tagtttttta ggtaaaactc ttcttaaatt ttaaaacgtt tcgaaaaatc
    26521 actaaatgct ttaatagcac ttgctaaaaa tggtttcacc atctcatcat taattaacct
    26581 tgattactta caatcttatg aatctgagtc aaataaaatt caggctgtgg cattacagag
    26641 acatttaaaa cctatactca tcgttttcaa ggtcagaaag agaatgattt tgaaaaggtt
    26701 cgtcaactct tctagataat tttggacaaa ttttgatcaa gaaacaaaaa gagcctatca
    26761 aataaggctt ttttatatga tttctatcca ccttgaggga atcgaacccc catctcaaga
    26821 accggaatct tacgtgatat ccattacact aaaggtggtc acaactttgt caataccctt
    26881 atagtatatc ataaaatgaa ataatatgaa ataacttttc taaccagaag acaataaaaa
    26941 gttgaggaaa acctcaactt tttagattta ttacaattca atatcaccga aaagatcagc
    27001 cattgagaat ccagtttgtg tttctgggag ttcgtagtca cgtcttgatt cacgttttgg
    27061 acgacgtggg cgtgattgac gtttttcttc tttgttgtct ccttcagctt gcgctgggcg
    27121 ttcttcaaga gctttgattg ataatgatac gcgctcatca gctgcattca cttcaagaac
    27181 tttaactgtt acttcttgtc ctacagaaag tacatctttt ggattttcaa cacgtttgtg
    27241 tgaaatttgt gaaatatgaa caagtccatc aatacctggt aatacttcaa caaaagcacc
    27301 gaagtcagtc aagcgtttta ctttaccttc aacaacatca ccttgagcaa gtttttgttc
    27361 aacgccgtcc catggtccag gtgttgttgc tttaagtgaa agtgacacac gaccagcttc
    27421 ttcgtcaatt gaaagaactt taacttcaac ttcttcacca actgaaacaa ctgatttagg
    27481 tgacacgtta cgttcgtgag acaattcagt cacgtgaaca agtccgtcaa caccaccaag
    27541 gtcaatgaaa gcaccaaaac ttgttaaacg cgctacagta cctgtaacga ctgcaccttc
    27601 tgaaatctta gagaacactt cagcacgagc ttctttagcg gcctcttcga taacttcacg
    27661 acgtgatagg atgaaacggt tttctgctgc atcaacttct ttgattttag catcaaactc
    27721 ttgtccaaca aatttttcag tgttgcgaac aaaacgagtg tcaatcattg aagcagggat
    27781 aaatccacga agtccttcaa attcaactga aaggccacct ttaacagcac gggtaccttt
    27841 aacagtaaca acttcgcctt cacgaccaac aagtttgtcc caggctttac gagcttccaa
    27901 acgtttttta gatactagga aagtaactgt atcagtatct ttacctacta cttgacgaag
    27961 aacaagtact tcaactgtgt cgccagcttt aacaaagtcg ttaatatcag catcgcggtc
    28021 gttagtcaat tcacgaagtg tcaagacacc ttcaacacct gttccttcga taacaacgtt
    28081 tgcttgaccg ttatcaacag ttaaaacttc cgcagtgaca acatcaccag ggttcacttc
    28141 gctaacactg tttagcaaat cttcaaattc attcattcta aaaaatcctc caacaaaagc
    28201 tagccaatgc tagcttttga taacaatata ttttctcaag gtaacccgca acgacaacaa
    28261 ctcttatctt tgacggtctc agggagcacc tgatacctct gactggggta gctggattcg
    28321 aaccaacgc
//
LOCUS       DAUGQX010000025        28000 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUGQX010000025 DAUGQX010000000
VERSION     DAUGQX010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28000
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.025"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            22..1194
                     /gene="sda1"
                     /locus_tag="VIA51_001022"
     CDS             22..1194
                     /gene="sda1"
                     /locus_tag="VIA51_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase Sda1"
                     /protein_id="HEQ8682967.1"
                     /translation="MSKHWRHLIIHSALTILATLFLGILPITENTSSTIYAESGTISN
                     NWSIEQHPNYYHVEGKAQLDIKNFPELYRTTERVYKKSGQSTKPVTVSNIHYSVLDGY
                     GRSGEAYGIITKDMIDMSAGYREKWESKPEPSGWYSYFFKNTNQRATESDYKHSPKNV
                     SKISNNIKASILLSNGNVRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNNDRK
                     GGMQYIENKVLDHIKRNPKVHVYYKATPVYQGSELLPRAVLVSALSSDGFIDETVRVF
                     NNVAGFNIDYQNGGLLSSTADVDINNVEENEIETTDDEIEEGIENEPDTDALKKDNKD
                     TSLQDTVYVASNGQSDVYWYNKDSMPKTVNLEKVVEMSEQVALTRGKHHSTQENIE"
     gene            complement(1310..2506)
                     /locus_tag="VIA51_001023"
     CDS             complement(1310..2506)
                     /locus_tag="VIA51_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8682968.1"
                     /translation="MTFLDNIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFNTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYQ
                     SVVGETDYKKACHAIKDAGYATASGYAELLIQLIEENDLQKWDKEILTNQKEVTMTTA
                     NEIVKYCVDLANSGMGVDKDGAYGTQCCDLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHAHQTVDTAPQNSDTIVETPKSGTFTLDVVEINIR
                     RWPSLASEVVGSYKQGDTVSFDSEGYANGYYWISYLGGSGMRNYMAIGITDKDGNIIS
                     LWGKLN"
     gene            complement(2617..2802)
                     /locus_tag="VIA51_001024"
     CDS             complement(2617..2802)
                     /locus_tag="VIA51_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682969.1"
                     /translation="MSKWFKKVGIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKDEE"
     gene            complement(2799..3098)
                     /locus_tag="VIA51_001025"
     CDS             complement(2799..3098)
                     /locus_tag="VIA51_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682970.1"
                     /translation="MHFDLLQAGAAAAALMSVFGLWKAVVTPFKKAMEANEFAMAQLK
                     DSLKELAYELKNLDRDREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            complement(3109..3729)
                     /locus_tag="VIA51_001026"
     CDS             complement(3109..3729)
                     /locus_tag="VIA51_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682971.1"
                     /translation="MRNWKVTGNYPQWDGTGAVVDTQVIITDDRGAVISEKVKKDLRT
                     ANDAEIIEAALEEFKKTAYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHVLTSGGKIDPDIYKGMLELIEPAKKGEYKEHDIFTVVDADKDTD
                     GVAGEGNLVFVYVNDKFTYDAQTLKDLEELEDKVTVIKYADLVKQD"
     gene            complement(3732..3893)
                     /locus_tag="VIA51_001027"
     CDS             complement(3732..3893)
                     /locus_tag="VIA51_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682972.1"
                     /translation="MQEKLLGKIINDLTLKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            complement(3902..5809)
                     /locus_tag="VIA51_001028"
     CDS             complement(3902..5809)
                     /locus_tag="VIA51_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8682973.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFKADGDTKSVKLANNKCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGSGESTGLFKNLEGALSQLKELNLELTDTVNSQ
                     LWAKIKLTTNGMLREYHRDNITTEIVESANGIATRISEDTDKKLALINETVSGIRRDY
                     QDADRQLSSTYQAGINGLKATMANDKNDLKAVIQATAQGLSQKYDDEIQQLSAKITTT
                     SSGTTEAYESKLADLRAEFTRSHQGMRTVLESRISGLQSTQQSTAYQISQEIKNREGA
                     VSRVQQDLASYQRRLQDTEKNYSSLTQTVRGLQSTVSAPNRGLESRVTQLAGLIEQKV
                     TRGEMESYIRGAGDSIMLAIKGKLPQSKMSASEIVSAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIEHTIT
                     SLLEGKVIRARNGAMMIDLNNSTIDFNSDASINFNSNNNALVRKSGTHTAFVHFGNAT
                     PKNFTRSALYASIGITSSGDGINSASSGRFCGARFFRTASGYEHTASVDQAEIYGDTI
                     IFADDFGINRGFKMTPTGVNTLVDINKMYYAIVALARCWKHLQNVGWDTTHPNFTSAI
                     MNEHSNYMTGI"
     gene            complement(5820..6455)
                     /locus_tag="VIA51_001029"
     CDS             complement(5820..6455)
                     /locus_tag="VIA51_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682974.1"
                     /translation="MAVQEIPDTYFYRLDSQSIDGTLLQKASLVVDQFYIKIDDYYSF
                     YTDQDVDVYKIISSTQADVYKANKYNYQSLSKPDTSVQKPSAAMGLYQSITIDGLPIA
                     RVICNNQVIWSQSAEPQEVYNITAYVDANVSKLNDYAVIDYNQDFATYGVVWHRVDKV
                     AVEVDGKIVAKLQKPVRTVAGGGAMLSIETWTYPFDGIDKYKNPTFKISQH"
     gene            complement(6455..7510)
                     /locus_tag="VIA51_001030"
     CDS             complement(6455..7510)
                     /locus_tag="VIA51_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ8682975.1"
                     /translation="MTLEERIPIKVLFDRKDAAEWQKLNPVVDDGELVVELDTHRLKV
                     GDGKLNYNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTSIA
                     DITKVGETLTITLSDDTQKTFSIPNGQKGDRGKGVESARVDEEGNLFVKFEEESEKLV
                     GNIKGQKGDKGDSLKFEDLTSDQIAQIKAKDVDLSAYATKAELKEIDVSKQLADYLSK
                     AEANSTYAKASHKHSLSDITDLNLDRYATKIELQNKASTYHRHRTSDIDGIDEYLKQT
                     DLPQDIVKQSDIRDVVRNAQLSGYVRLADIQYQLNNIGKLKDVATGQYLSVRVVDKGK
                     VPYNTSGLIVFERSGGK"
     gene            complement(7507..9489)
                     /locus_tag="VIA51_001031"
     CDS             complement(7507..9489)
                     /locus_tag="VIA51_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8682976.1"
                     /translation="MITFLDHRDIEYGAISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLMRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINRRTDKELEEFRETL
                     KNLALPEEAIKKITDAIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEIIGTDGKTRY
                     NKNLLVGNPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLNKVAITLIQANN
                     KGLKLVLTPTKAKMEPQTFEVTKDKQSIEVYPLSYKGVLTGDWYKSKQIDLTASEGQI
                     LALDMAYKAVVDAKGATITAKQSSNPKIILDGRRDR"
     gene            complement(9499..10341)
                     /locus_tag="VIA51_001032"
     CDS             complement(9499..10341)
                     /locus_tag="VIA51_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8682977.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(10353..14735)
                     /locus_tag="VIA51_001033"
     CDS             complement(10353..14735)
                     /locus_tag="VIA51_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEQ8682978.1"
                     /translation="MPGTFDGSIFADIGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVDIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGRQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVVQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSALSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINTVLGDFAHTGELSGQAFDNLKAKITSLAPKVIALWA
                     VMNPASAIATIMPLLSLFGKVGLALGSLGASVGVFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IDQLLNTAVTKGPSIIQGLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQ
                     LITSLVQGIGQNATSLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIGSFGNSLQANLPSIISHGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIVQSAVQIIQSLVSGLTQALPQIIAAG
                     IQLVVQLAVALIKGLPQIISAGIQLITGLGKAMLEAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATAMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFA"
     gene            complement(14750..14983)
                     /locus_tag="VIA51_001034"
     CDS             complement(14750..14983)
                     /locus_tag="VIA51_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682979.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            complement(15058..15513)
                     /locus_tag="VIA51_001035"
     CDS             complement(15058..15513)
                     /locus_tag="VIA51_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682980.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            complement(15567..16166)
                     /locus_tag="VIA51_001036"
     CDS             complement(15567..16166)
                     /locus_tag="VIA51_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8682981.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQISESAGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            complement(16178..16537)
                     /locus_tag="VIA51_001037"
     CDS             complement(16178..16537)
                     /locus_tag="VIA51_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682982.1"
                     /translation="MDYSPETLYLKKVKNRLGALGIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARLLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            complement(16541..16885)
                     /locus_tag="VIA51_001038"
     CDS             complement(16541..16885)
                     /locus_tag="VIA51_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ8682983.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQRLLHYRVVSPALYSIYLELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            complement(16882..17160)
                     /locus_tag="VIA51_001039"
     CDS             complement(16882..17160)
                     /locus_tag="VIA51_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682984.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            complement(17171..17527)
                     /locus_tag="VIA51_001040"
     CDS             complement(17171..17527)
                     /locus_tag="VIA51_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ8682985.1"
                     /translation="MGDKQLIDDIKLFIGISKDDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            complement(17539..18426)
                     /locus_tag="VIA51_001041"
     CDS             complement(17539..18426)
                     /locus_tag="VIA51_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ8682986.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAESIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            complement(18439..19008)
                     /locus_tag="VIA51_001042"
     CDS             complement(18439..19008)
                     /locus_tag="VIA51_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8682987.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLTTTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            complement(19164..19430)
                     /locus_tag="VIA51_001043"
     CDS             complement(19164..19430)
                     /locus_tag="VIA51_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682988.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            complement(19433..19621)
                     /locus_tag="VIA51_001044"
     CDS             complement(19433..19621)
                     /locus_tag="VIA51_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682989.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            complement(19652..21097)
                     /locus_tag="VIA51_001045"
     CDS             complement(19652..21097)
                     /locus_tag="VIA51_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ8682990.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRRDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFNCRTTLIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNG
                     HKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDRVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            complement(21057..22589)
                     /locus_tag="VIA51_001046"
     CDS             complement(21057..22589)
                     /locus_tag="VIA51_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8682991.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYNIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            complement(22605..23882)
                     /locus_tag="VIA51_001047"
     CDS             complement(22605..23882)
                     /locus_tag="VIA51_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8682992.1"
                     /translation="MTIKQRPKINIVIKYPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            complement(23872..24324)
                     /locus_tag="VIA51_001048"
     CDS             complement(23872..24324)
                     /locus_tag="VIA51_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEQ8682993.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            complement(24414..24830)
                     /locus_tag="VIA51_001049"
     CDS             complement(24414..24830)
                     /locus_tag="VIA51_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEQ8682994.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            complement(24827..25018)
                     /locus_tag="VIA51_001050"
     CDS             complement(24827..25018)
                     /locus_tag="VIA51_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682995.1"
                     /translation="MKIEFFLKQGPTKSVSNYGEICIDEVIGAMKNNDVIALNGKNNA
                     VIIPKQNISHVIIHKEVTG"
     gene            complement(25008..25859)
                     /locus_tag="VIA51_001051"
     CDS             complement(25008..25859)
                     /locus_tag="VIA51_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEQ8682996.1"
                     /translation="MEIKCGNCLELLAELTDGLIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASQKLTKNGGMIIFNDWKNLGDIARHCEKNGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGVWVVRKKSKWVFNRKSEKYDRPEYRYPVVAGAEKTQH
                     PTQKPVALMKDIITRHTTKGAVVLDPFMGSGSTGVACLLTGRDFIGYELNKDYFNIAN
                     KRIAELTGNGGVGMNIIHRMENGIDAVGDLTTYAVPCCPECKNETYSQKHCPFCGENL
                     MEVANEN"
     gene            complement(25868..26134)
                     /locus_tag="VIA51_001052"
     CDS             complement(25868..26134)
                     /locus_tag="VIA51_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682997.1"
                     /translation="MTEELIKPLLEEIKRKDDRLYMQSNVIAVLMTAVIMLLMISIAL
                     QNHYEPQITGLRTQLSRTQKQLKRASEDRARQTKRIAELTGNGG"
     gene            complement(26131..26298)
                     /locus_tag="VIA51_001053"
     CDS             complement(26131..26298)
                     /locus_tag="VIA51_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8682998.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLKFWNSCEAT
                     VKEKYTREWKK"
     gene            complement(26299..27621)
                     /locus_tag="VIA51_001054"
     CDS             complement(26299..27621)
                     /locus_tag="VIA51_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ8682999.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKSTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDFERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            complement(27618..27893)
                     /locus_tag="VIA51_001055"
     CDS             complement(27618..27893)
                     /locus_tag="VIA51_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEQ8683000.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
BASE COUNT         7591 a         6243 c         4902 g         9264 t
ORIGIN      
        1 taacaaaagg aggacataaa tatgtctaaa cattggagac atctaattat tcactctgct
       61 ctgaccattc tagctacgtt atttttaggt atactaccaa ttactgaaaa tactagtagt
      121 accatttacg ctgaatcggg cactatttca aataattgga gtatcgagca acaccccaat
      181 tattaccatg ttgaaggtaa agcgcaactg gatattaaaa attttcccga actttatcgt
      241 acaaccgaaa gggtctataa gaaaagtggg caaagtacta aacctgttac agtttccaat
      301 atccattact ctgtacttga tggctacggc cgttctggag aagcttatgg tattatcaca
      361 aaagatatga ttgacatgtc tgctggctat cgtgaaaaat gggaaagcaa accagagcca
      421 agtgggtggt attcttattt cttcaaaaat actaaccaga gagccactga atccgactac
      481 aagcatagcc ccaaaaatgt gagtaagatt tcgaacaata tcaaagctag tattctctta
      541 agtaacggaa atgttcgtaa cggctacctg tttgatagaa gtcatttaat agccgatagc
      601 ttaggaggaa gaccttttag aaataatttg attacgggta cccgcaccca aaacgtaggt
      661 aataatgatc gtaaaggtgg gatgcagtat attgaaaata aagttttaga tcacattaaa
      721 agaaatccta aagtccatgt ttactataaa gcaactcctg tatatcaagg atccgaattg
      781 ctacctagag cagttttagt gtctgcttta tcatctgatg gatttattga cgagacagtt
      841 cgtgtgttta ataatgtagc aggttttaat attgattacc aaaacggtgg actcttatct
      901 tctactgctg acgtagatat taataacgtt gaagaaaatg aaatcgaaac tactgatgac
      961 gagattgaag agggaatcga aaacgagcct gacacggatg cactaaaaaa agataacaaa
     1021 gatacttctt tacaagacac tgtatatgtg gcaagtaatg ggcaatctga tgtatactgg
     1081 tacaacaaag acagtatgcc taaaactgta aacttagaga aagttgtaga aatgagtgaa
     1141 caagtagctt tgactagagg taaacatcat tcaactcaag aaaatataga ataacaaatt
     1201 caacagacca actagaactt gaaatagttt ttatattctt attagttatg cataagcata
     1261 cgaaacacac aaaaaaccgc cctcaatcaa gagagcggtt ttgtcttatc taatttaatt
     1321 taccccaaag gctgataatg ttaccatctt tgtcagttat cccaatagcc atgtaatttc
     1381 gcatacctga gccgccaaga taactaatcc agtagtagcc attggcataa ccctcgctgt
     1441 caaagctgac agtgtctcct tgtttgtagc tacctactac ttcactggct aggcttggcc
     1501 aacgtctaat attaatctcc acaacatcaa gcgtaaaggt accagatttt ggtgtctcta
     1561 cgattgtgtc agagttttgt ggtgctgtat ctaccgtctg atgagcatgg tcaacaggta
     1621 acctaatcca gccgacaacg ccagtaaaat cacgagtatt aaaacgggct ggtccaccta
     1681 cttgtaagct atcccaatta ccgtcaatat tttgctcaac ggttttaata gtatagccat
     1741 cactatcctc gatgacagct cctgtatgtc cgtagggact accagctacc tccatgacaa
     1801 aaaggtcact agctttggga ttgactccag gggcattata tatgacctct agcccttgcg
     1861 cagatgcgct atttaacagg tctatggcat taccccataa atcaatgccg aaccagtttt
     1921 tgacgataaa acatggtaag tcacagcatt gcgtcccata agcaccgtct ttgtcaactc
     1981 ccatacctga attggcaagg tcgacacagt attttacaat ctcatttgcg gttgtcatcg
     2041 ttacctcctt ttgatttgtt aagatttcct tatcccattt ttgtaggtca ttctcctcga
     2101 ttagttggat aagcagctcc gcatatccac ttgccgtggc ataacctgcg tccttgatag
     2161 cgtgacaggc ttttttatag tcagtctcac caacaacaga ctgatagcgt ggattatcgt
     2221 ttaaaaactt gccatggtcg ataatgctat cagtccagct atcataggcc ctaaatcggt
     2281 ccacaatatc cgtgacgata ccaggctggt actcctcctg cgtcttagtg ttaaaagact
     2341 tacctgtcca gcttgcatca gctttaatcc caaacagagc gttatgtggg gcatgtttac
     2401 cccacccgct ctctaagatt gcttgtgctg cggtcaagga tggcaagatt ttgtacttag
     2461 tccagccatc taagcagcct tgcttaatgt tatctaaaaa ggtcatctgt cctccttatc
     2521 tacaaacggg taaaagataa gagcaaccac agataatggc acatacagta ttgcgattgc
     2581 tagtattaac gctaatcgtg tgattgctcg catggcttat tcctcgtctt taatttgtga
     2641 cacgttcatc aggacacatg ttagtcctga tagcagtacc gctgacaaca ttgttggcca
     2701 gttaatatcc gtaatcaaca cgcttgaccc gataagacca accgcagttt gtgccattgt
     2761 tttgattgtt ttaattccta cttttttaaa ccatttgctc atttttcttc ccctttttta
     2821 aatagcgtga taatacgctc tttgttgata ataacttcgt cttcgacgcg acctaaacgc
     2881 tcttcgtgac gatcgataat ttttttggta atttcacgat cgcgatcaag atttttaagc
     2941 tcataagcta actctttgag agagtccttg agttgagcca tggcaaactc attagcttcc
     3001 atggcttttt taaaaggcgt tacaactgcc ttccaaagac caaaaacaga catgagagcc
     3061 gctgccgcag ctcctgcctg tagtaaatca aagtgcatct aaccacctct aatcctgctt
     3121 aaccaaatca gcgtacttga taactgtgac tttatcctct aattcctcta aatctttgag
     3181 tgtttgtgca tcataagtaa acttatcatt gacataaaca aagactaagt tcccctcacc
     3241 ggctacaccg tccgtatctt tatcagcgtc tacaactgta aaaatatcat gctctttgta
     3301 ctcacctttt ttagcaggtt cgatgagctc taacatgcct ttataaatgt caggatcaat
     3361 cttgccaccg cttgtcaaaa cgtggatggt ttgcaagtta atcatctttt gcgtgcgttc
     3421 agcggacact ttagctagtc cagcggctgt ttgagcagtc ttggcagtct tagcggtttc
     3481 ttgtgagatt ttttcaaggt cgtctacttt ttgcacggct tcgcccattg caatttcgac
     3541 gtaagcagtc tttttaaact cctctaaagc agcctcgata atttctgcat cattagctgt
     3601 tctcaagtct tttttgacct tctctgagat gactgcacct ctgtcatctg taataattac
     3661 ctgtgtatca acgactgctc ctgtaccgtc ccactgtggg tagtttcctg ttactttcca
     3721 atttctcatg tttatttacc ttcttccttc ggtgctgttg cttcatccaa ttgtgcgttt
     3781 aattcttcca attcgatttc atgctgtgct tttaattgag cattttccag cgttaaatta
     3841 gcgactttaa gtgttaaatc gttaataatt tttcctaata atttttcttg cattgtttct
     3901 cctaaattcc agtcatataa ttgctatgct cgttcatgat agcgctagta aaattcgggt
     3961 gtgtagtatc ccagccaaca ttttgtagat gtttccagca ccttgccaaa gctacaatcg
     4021 cataatacat tttattgata tccacaagtg tgtttacacc cgttggtgtc attttaaatc
     4081 cacggtttat accaaagtca tccgcaaaaa tgatggtatc tccataaatt tctgcctgat
     4141 caactgatgc tgtatgttca tatccgctag ccgtccgaaa aaaccttgct ccacaaaaac
     4201 gaccagatga cgcgctattg ataccatcac cagatgaagt gattccgatt gacgcataaa
     4261 gagccgacct tgtaaagttt tttggtgtcg cattaccaaa atgcacaaaa gcagtgtggg
     4321 tacctgattt tcgaacaagc gcattattgt tgctgttgaa attgatggat gcatcgctat
     4381 taaaatcgat ggtagagttg tttaaatcaa tcatcatagc accatttctt gctctgatga
     4441 ctttaccctc aagcaaactt gtaatcgtat gctcaatcct tgctttaata aagttagcat
     4501 ctaaaccaac aatgctgcta gcgttgagat taatcacatt gattttgttt gcatcgattg
     4561 tcccaccgat aatctggtcg gcttttagct tgataaactc accaagtttt gcgccaaacg
     4621 ctccattaac cgtggtattg ccgtctaagg cgatacgctc gccagagatg cggacaccgt
     4681 agccgtttaa attaatggct gagacaatct cacttgcgga cattttgctt tgcgggagtt
     4741 tgcccttaat cgcaagcata atactgtcgc ctgccccacg aatataactc tccatttcac
     4801 cacgagtgac tttttgttca atcaagccag ctagttgtgt gacacgggat tctaaccctc
     4861 ggttaggggc gctgacagtt gattgtaacc ctctaactgt ctgggttaag ctactgtaat
     4921 tcttctcagt atcctgcaat cgccgctgat agctagctag gtcctgttgc acacgactaa
     4981 cagcaccctc acgattttta atctcttgtg agatttggta ggcagttgat tgttgcgttg
     5041 attgcaaccc actgattctt gactctagca ctgtccgcat gccttgatgg ctacgagtaa
     5101 actcagctcg taagtccgca agcttactct cgtaggcctc tgtggtgccg ctagatgtcg
     5161 tggttatctt agcagataac tgctgtatct catcatcata cttttgcgac aaaccttgag
     5221 cggttgcttg tatcacagct tttaggtcgt ttttatcatt ggccattgtg gcctttaggc
     5281 cgttaatgcc agcttgataa gttgatgata gctgtctatc agcgtcttga tagtcacgtc
     5341 taatacctga gactgtctca ttaataagcg caagtttttt atcagtatcc tcactaatcc
     5401 gtgttgctat accatttgca ctttcgacaa tctctgttgt gatgttatca cgatgatact
     5461 cacgcaacat gccgtttgtt gtgagtttga tttttgccca aagctgagaa ttaacggtat
     5521 ctgtcagctc taaattaagc tcttttaact gactgagcgc tccttccaag tttttaaaaa
     5581 gtccggttga ctcaccgctg ccctcaacaa ccactggcgc cacgtagtta gttggcttac
     5641 cccctcgctc aatcatgagc tggttaaagc gagtcgtacc gatacatttg ttattagcta
     5701 atttaacgct ttttgtgtca ccatcagctt taaatgtata ataagcacgt ccgtcagagc
     5761 caatcgttaa atttgactcg tctattaaaa gtgttggatc tctactcaat tgttacctcc
     5821 taatgttgcg aaattttaaa tgttgggttt ttatacttgt ctatcccatc aaacggataa
     5881 gtccacgtct cgatagacag cattgcgcct ccgccggcaa ctgtccgaac tggtttttgt
     5941 agcttagcaa cgattttgcc gtcaacctca acagcgactt tatcaactcg atgccaaaca
     6001 accccataag tcgcaaaatc ctgattgtaa tcaatgacag cataatcatt taatttagat
     6061 acgttagcgt ctacatacgc tgtaatgttg taaacttcct gaggctctgc tgattgagac
     6121 caaatgacct gattattaca aataacgcga gctattggca gtccatcaat agtaatcgat
     6181 tggtacaaac ccatcgcggc agaaggcttt tggacgctag tatctggttt tgataatgac
     6241 tgatagttat acttattagc tttatacaca tcagcctgtg tgctagatat aattttatat
     6301 acatcaacgt cttgatctgt gtaaaagcta tagtaatcat ctatcttaat ataaaattgg
     6361 tcgacaacca aactggcttt ttgtaataaa gtaccatcaa tgctttgact gtctaagcgg
     6421 taaaaatacg tgtctggtat ctcttgcact gccattactt acctccagag cgttcaaaaa
     6481 caattaatcc gcttgtgtta tatggcactt tacctttatc aaccacacgg acagataggt
     6541 actgacctgt tgccacatct tttagctttc cgatgttgtt taactgatac tggatatcag
     6601 ctaatctaac atagccgctt agctgcgcat ttcggacaac gtccctaata tctgattgct
     6661 taacaatgtc ttgtggcaga tcagtttgtt taaggtattc atctatacca tcaatatcag
     6721 atgttctgtg ccggtgatat gtacttgctt tgttttgtag ctctatttta gtcgcatacc
     6781 ggtctaggtt tagatcagta atatcactta gcgagtgctt gtgacttgct ttagcataag
     6841 tgctgtttgc ctctgcttta gacagatagt ctgcaagctg cttactcaca tcaatctctt
     6901 taagttctgc ctttgtagcg taggcagata ggtctacgtc cttagcttta atttgggcga
     6961 tttggtcaga agtaaggtct tcaaacttta aggaatcacc cttatcacct ttttgacctt
     7021 tgatgttgcc tactaacttt tcagattctt cttcaaactt gacaaaaagg ttcccctctt
     7081 catcaactcg agcactctct actccttttc ctctatcccc tttttggcca ttagggatac
     7141 taaaggtttt ttgagtgtca tctgatagtg tgatagtaag cgtctcaccc actttagtga
     7201 tgtcggcaat acttgtccct ttatcacctt tttgaccttt gatgttgcca agcttagtct
     7261 ctttgtcgcc aatccacaca gacaagtcac cattttcgga tagctgtact ttagtgatag
     7321 attctccttg aggaccttcg tagtaaggca agtcgttgta attcaatttg ccatctccga
     7381 cctttagcct gtgagtgtct agctcaacaa ctagttcacc atcatcaaca acaggattta
     7441 atttttgcca ttcggcggca tccttgcggt caaataagac tttaattggt attctttctt
     7501 ctagcgtcat ctgtccctcc ttccgtctaa aataattttt ggattgcttg attgtttagc
     7561 tgtgattgtt gcacctttag catcaaccac agctttataa gccatatcca gagctaaaat
     7621 ttgcccctct gacgcggtta aatctatttg cttagattta taccaatcac ctgttaaaac
     7681 acctttatag ctcaaaggat agacctctat agactgttta tccttagtga cctcaaacgt
     7741 ctgtggctcc atcttagcct ttgtcggtgt cagcaccagc ttgagacctt tattattagc
     7801 ctgtatcagc gtaattgcca ctttatttag tggctcacat gtctggctaa agctaatcgt
     7861 ataggtctcg ccacgcttga aaccaccatc attggcttct acctcaataa aatcctcatc
     7921 aattttttta acacgattag ggttgccgac cagcaaattt ttgttgtagc gggtcttacc
     7981 gtctgtgcct atgatttcgg cgtttagacg ggatgtctcg ctcgtttcac tgactttgtt
     8041 tttgaggtcg tcaaagcttt gtttaatcga tgggatgtca tcaaccttga tagcatctgt
     8101 gattttttta atggcttctt ctggtaacgc taggtttttg agtgtttctc taaactcttc
     8161 aagctctttg tcagtgcgcc ggttgatttc ttcttgcgct tttttggctt tttcgattgc
     8221 ctcagagatt tgtttttcga ggtcttcacg ccatcgttct gggtcgttca caacctcggg
     8281 ttcctcccac tcagcaccat tccaaaagta cattctagta gtatcaccaa cttttagaaa
     8341 taatatgtct ccttttttta aggttccttt tggttcatct ttgggcattt ctgtgccacc
     8401 gtaaacagta tttttcccat cagcagatac tagtgcttgt gttgctactt caattgcaga
     8461 agcaatatct gcatctatct gattgattct actgtttata gacagacttc ctacgctttg
     8521 ttttttcaca gatccgatat cattacaagt gacttcatgt tttactaaag ctccagttgc
     8581 gtcgtagtag cttgtaaaag aaactatccg tatacgctct tgaaaaccta aagtctcatt
     8641 tatcgccata atgtagtcac cagcaaccgg cctctcacat ctataaccag ctctcattaa
     8701 atcttccata tcaattttta ctgatatctt ataagaattt tcaacattac tttttaaagc
     8761 ttcttttaga ttatctgcca ccgtgaagcg ctcatccgtc agaggcgccc cttcaagtcg
     8821 accgtactcc ttggcaagag ggctttcgta ttccgcctca agtctcccct tagagtggtc
     8881 ctctgggtcg gtccatgcac caaagccttt ctgataggta ataaagctat caatattttt
     8941 ttcaatggta agatcattca tgttgaaatt ttttcgtacc actgttgaca gatcagtacc
     9001 tatgtttttt aatagccgaa caactttccc gctgactgaa aactcaagtc cggtcgcttt
     9061 aataatctca ttgaataaat ctaacctaga cttataatta aaagattgtt ttctaaatgc
     9121 gttcacacct acttctagct tatagcggta cccactacct ttaaatactg tctctagata
     9181 ggtatcaatg gtatgagacc catctccgag accctcatag atactactct tgctgaagtc
     9241 ccaaaaaaat tggtgtatgg catcaaacga aacttgcgtt ttttgaccaa catcaacagg
     9301 ctttgcgtaa ataacaacgt aatactcatc ttcaaatcta agtcgccacc ctctatcgat
     9361 attattgagg acatcactgt ttgtataaat ttccccgctc actgagcgct caccattaac
     9421 agcattagta tgcctaatga cactaatggc cccatactca atgtcacgat gatccaaaaa
     9481 agtaatcatt agaccctcct atttatacaa ctctacaaaa tttaaaatcc taatcgtgcc
     9541 aagaaaatcc gttttgtaag taattctctt gttaggatta ggattgaaga taaaatactc
     9601 atagttcgtt ttagcattga cataatttcc gtttagtgtg gtagctatgc ctgtcaaaag
     9661 taatttatca ctattttgta gctggctatt ctgcttaaac tcaaagcgcc tgccatcaat
     9721 ttcaatataa aaattagtct gacctccaga gggagtaagc tctataataa aaggccactc
     9781 taactgactt gctttagcgg ttcctccata ggcaaaactg ccccctgata gagttatgtc
     9841 ctttggtttt gtctcaccga aaggtaattc agcagttctt agtgtgaagg aaagattata
     9901 ttttagtcct tgactggttt ttcctataaa ttcataagcg atagtgtcgt ctaggatgac
     9961 tttaaatcta tatttccaag gtttatgagg agagccaata agttgcaggt ctcctgtgct
    10021 ttcccctgga agctcaaagt taaatagatc tgagttttca gggtacatct tagtcacgta
    10081 gaaaggttcg tcaacaacaa gcagagcgtt tagttcgtcc tgtttgtcca aaactccttc
    10141 tacatcgctt accgtcactc ttcctttgac cttaagcgtt ttagtcgtaa aagtagcccc
    10201 atcgtagatg taaccactcc ttcctttgac tgctcggtgt gatacagata gtagaggagc
    10261 actatcttca atagcaatat tataaatacc aaagtcagac aatctagttg cctgactctc
    10321 tttttctatt aataaatcca aaatactccc ttctaggcaa aaacaaaata agaatcttta
    10381 gattgctctc ttgattcttt ttctttaaca gccgtgtaaa ttttatctcc aacaatctca
    10441 ttatgcactt caaagatagg ctctgacaat tgagactgcc taacctcttc gctaagatta
    10501 tcaagagagg tattgattcc actattatta actttagcag atgttgaaac agtactattt
    10561 accccccagt tttgatcagt aactgctgtt gcgtatgctt tacctagact attgatctca
    10621 cctatccact ctgccatacc gagggcaaac ccctctccag taaatgctcc tagtgtttta
    10681 gtgacacgag atggcgagtg aatatccaga gcgcgtctaa ttgttgctgc tacgttagcg
    10741 gcaatgctgt tagctattgc gtagattgtg cctgcgctac tagctagacc attagcaaaa
    10801 ccttgacctg cataagctcc tgcagaagac atctgccctg ccaaagccct gaatattgag
    10861 aggatcttct gacaagcatt attagacacc gcggttgcac gagacatccc agaagtcact
    10921 gaacttacaa ggtttgccat agattgcttt gcagtactgt taatgctact aaatcctgtt
    10981 ttaaccgcat tggctatccc attcattgag gttgttgctg aagtcttcgc cttattgaag
    11041 ccagactcaa ccgccgagga caacctattg gcgcttgagg ttgcagaggt tgctgcagaa
    11101 gacatttcac ttgtcacgct attagacaga ccagaggctg ctttagttga gtttgactgc
    11161 attgatgcca gactgttact cactcctgag ctcatagctt gcgcctgaga agttgcactt
    11221 gtgctagcgg ttcccatgtt tgcaccaaca ccactagcta agctgagcgt atgattaatg
    11281 gcgtctagat tcattgaaga agtcgcacca ttaacccctg aagccatttc ttgagcctga
    11341 gtagtagcgt taatattagc cacagacata ttagcgctaa tgccactcgc aagagacatt
    11401 gaatcattca acccctgaag actcatcgtt cctgtctgag cattaacatt attagccatc
    11461 tgtgtagcat ttgatgtagc gtttatatta gcaagctctg tattttgact aatgctatta
    11521 agcatagatg tcgtatctgt attggcttga ttagccatag ctgttgtttg agtaccaaca
    11581 ttcaaggcca tggccgtggc gtccgcagag actttagctg tacttgtgga actcttacct
    11641 gtgatttgat cccacatcga actgaatccg ctcttaatac cttcccaaac tcctgaaaga
    11701 gcatttggga tagcctctaa catggcttta ccgagtcccg taattaattg aatacccgca
    11761 gaaataatct gtggaagtcc ctttatcaag gctacggcta gttgtacaac aagctgaatg
    11821 cccgctgcga taatctgagg cagagcttgc gtcagtccag aaactaaaga ctgtataatc
    11881 tgtacagcag attgtacaat ctggggtaga ttttgaataa tcccctgcac aaggctaata
    11941 atgatttgaa tgccaccttg aagtaactgc ggtaaaaact gtacaattcc agatacaaaa
    12001 ctcgtaataa cttgagtagc tatctgcaga acagttggca acatttgagt aattccctgt
    12061 acaagattca ccaaaatagc tataccgtgg ctgataatac taggaaggtt agcctgtaaa
    12121 ctgttcccaa aactaccaat gatttgctgt gcttgctgga taataagagg tatattttga
    12181 actatgccgt tgacaacatt taataatagc tccattccaa cagaaataag ctgcggcaag
    12241 gcactcgcaa ttgagctaac aaaactacca atgattttta ttgctgaact aattaaactc
    12301 gttgcatttt gtccaatacc ttggacgaga ctggtaatta gctgaacgcc agcttgaatt
    12361 ataaccggta ataacactgt gatagcattt gcaaatttag caatcaattg agtaccacta
    12421 gctatcaaag ctggtatttt agaagtaatc ccttttacaa ggccttgaat aatgctaggg
    12481 ccttttgtta cagcagtgtt aagtagctgg tcgatttgtg cgccaaactg gctattaatc
    12541 aaaccaagtc ctgccaccac aagtcctagg atagcggccg gtcctatggc cgccagtgct
    12601 aaactcacaa gactggacat tgcgcttgtc atagttccaa gcacagatag cccacgccct
    12661 gctgcggtag caaaaacgcc aggtaatccg cttagagttg ccgcaaaggc accaacaacg
    12721 ccgctggcac tagctatccc actagaaatt atgccgccaa acaccccgac agaagcccct
    12781 aagcttccta aagctagacc aacttttcca aatagagaaa gcaaaggcat tatcgttgct
    12841 atagcgctag cggggttcat cactgcccaa agggcaatga ccttaggggc taaagaagtg
    12901 atttttgctt ttagattatc aaaagcctgc cctgataatt caccagtatg tgcaaaatct
    12961 ccaagaacag tattaataag agcaaacacc tctttaacgc tggcgcctaa tgggctaaag
    13021 tcaatattga tagactgttt tagcctagcg aatgctgcaa ctgcatttgg aataagagaa
    13081 ttaatcgtat caaaaacgct ggttattgcg ggcttcaggc taagaagtgt ttcagcaatg
    13141 gtcttcatac cattagcttt agccgcttca tcaaaggctg aaatcatacc tgctacgcct
    13201 tttacaacgg cggtatgtac gttcttccac gcagttcgga ttccaccagc cgatgattgg
    13261 gccatctctg caaatccgcc ttgggcatcg ttaagctcaa tcattttatc tgcgaactct
    13321 tgtgcagtga ttttgccatc agataaggct gattttaaat cttgtacgcc atttttacca
    13381 aaaccgaagg cttccgccat tttagacatt aaacctggcg cagcttctga tacagagtta
    13441 aactcttcag cttgaatttt tccagacccc aacgactggt taaactgcct gagtgcttgc
    13501 tcagcccctt cagttgttgc cccgtaaccg atcattgcgt tattgaaggc gagggctaaa
    13561 ctagtccctt tatctaaact tcctgtggtt atggcgagct gttgagcgct ttttacagca
    13621 ctgtctagag gagttggcag accttcaatt ccttttgata gcttatcaat tgatgcctta
    13681 gattgttcag cagaataccc aaatagcgcc atcgttttcg gaaagcggtt catggtatca
    13741 acgcgactaa ccgccccgtc tattgcccca gtaatagcgt gcatagcttt ttgaacaaca
    13801 gccattaaac taaaggcctg cacgatgctc atcactgtac ttttgagtct ctctccagca
    13861 gaagaggtgt tggcgaattt ctggctgatt ccattcaagg aagtagccgc agaactagac
    13921 attctgctaa aaccattgct aagactactc cctattttac ttgataaatt agctaaactt
    13981 gaggtcagcc gaccaaacaa actagtactc actttgtttg cgaaagcaga cgccttagct
    14041 gatacagaac taaaaaaatt attccatgac tgtaaggctg ggttcaagac ttgccgacca
    14101 agtgaattag aaatcttccc tccaacagac tgtatagagc tattcagggt agaaacggat
    14161 gaggcaattt ttctaaacgc tgttccgaat ggtcgcggaa gcttgcctgc gaccgtttcg
    14221 aatattgcag ataagttatt aagcttacta cttgccctct gagttaagat atcaactcca
    14281 gtcgcagcct tggcaaatgc agatcttatc ttaccaatat ccacaagatt ctgaagttgc
    14341 atttttgttt gattaatgaa accggttaag ttaccccgta ttttgtcaat aacacttgca
    14401 actggaataa tgattttttg aaaaccattc tttatgggtt cgggaatttt ttcgccaatg
    14461 gaagctgcta tgcgttgaat ttcaccaata ctcagtttta aaccagtagc gtaggcggaa
    14521 ccaagtctct ttccgagcga ttcgccgttg ttcgctaatt gggccatgat ttgtccaatg
    14581 atttgaacca ttttattact actgttaacc gctgtatctt gggcttttct gaaagcattc
    14641 tgagtcgtac taacaatacg agccatggcc tgctcatagt cctttgtgtt ggcaccaata
    14701 tcagcgaaaa tagaaccatc aaacgttcct ggcatctact cctccttatc tatctatttt
    14761 gaaaatgatt attaagcatt tgtattctct caacaatact gctatcacta tcggcttggc
    14821 tacggctagc tttttgatac gatcttttga tagttagcct atgcttatcg tatttgagct
    14881 tacctacatc aaccttttta gcatttaatg tatatctaag ttttagagac aattcagaga
    14941 ggttctcgcg ctcagcaacc tgcttatact caagcccctc cataatagcc tctagctccc
    15001 acttagtaca tttatagata gtatcaatgt ctgtgagccc taaccgtgcg caatttacta
    15061 agatactgcg ttgctcattc ttccaatcat gtcttcgata atttggattt gagttgcgtc
    15121 cgtgtcgtcc ttcgctttga gataacgagc tgatttctcc atgttttcga tatatttcaa
    15181 aatcttcgct ctgaaaaaac cagaatcaac catttctttc tctatttcag caaacaaccc
    15241 ttctgttgtt ccttcttcat caacagcttc tgcaattgca tctagaattt catcttcagt
    15301 tagcgctttt tttccgcttc ccgcagataa acgcacaagg tcaacaatgg cgctttcatt
    15361 acgctctaag atattgaaaa acaaagcacc aacaccatct gcattgcgct ctcctgtttc
    15421 tgggttaatt gttcctagtt tattattgat cttaaacata gttttaaaat caaatttaat
    15481 atcgatattt cgtttcgctg ctgtaaattc cattatttta tctccttttt aaatcaaaat
    15541 ggggcagcag ttgccgcccc tgtgtactac ttagtgatat tatcgtagtc gccagtagta
    15601 tcacccggat tttgatagcc gtatacgttt tctagcattt caatttcttc tttcgtgaga
    15661 gggaatttac catcttgtaa ggcccctaca atgttagcgg tgtaggacat ttctactaag
    15721 tctgaaatac cagtaccgcg ttcgatttcg tcaatcttgg cgtacccaaa cttagcaggg
    15781 taaacatctt tcttgggtcc agccgattca gaaatttgga tctgttcttt gacactttcg
    15841 tcggcaatga cttcccaaat tttgatagat ttacctgttt tcttagcttc ctcgatgaca
    15901 gcaacagatg gatctgtcgg tacaaagtac gttgtcaaat caatagagtg ttcatctgta
    15961 gccttctcaa taacgcggcc ttgttgggtt tgctcatcaa tgtattcacc gcccatggtt
    16021 gtagtaccat cggtacgata ggctggcagc aaagccttgc tacctttttt agcatcaact
    16081 gattggatga aataaaaaat ctttttccct acaatcggtt tacctgttgt aatttcaata
    16141 gttgttcctt ctttagtgtt tgccatttag gtctccttta aaatagtgtt tctgtaatgt
    16201 tgatagcaac tctatagact tctcgtccta ttgaattatc taccaaaatc tgagccttta
    16261 tttggttatt ccgcccaagt agtctaagca ggcgagcttt aatctcttct gcatccaaac
    16321 gactatcgcc aggtaagaaa gcatcgatat tcaggctaaa atcgtcaata actgctccag
    16381 tttgagctgt ttttgacaag tctgatatat ttgtacctac aacaataaaa ggctctaaaa
    16441 cgtctgattt aggcaattta aaatagattg gtatgcctaa agctcccaat ctatttttta
    16501 ccttttttaa atatagtgtt tctggtgagt aatccatgca tcacctctta aacatttttt
    16561 tgagattagc cattagcaca ggccattctt ttctcagggc agggtctaaa aacggttgag
    16621 cttccatttt acgagtacct aattcaagat aaatagaata taaagcagga gaaaccactc
    16681 tatagtgtaa gagtcgttgt tgctcattgt agatttgagc tctcagccat ccagtatcaa
    16741 ccggggctag tattttagcc tgtctctcaa tcctagcagc tgatttacta agctctttat
    16801 ctacagcgat tcgtactgac ttctgcttgc gctcaacgct gcgtaaaaac ctatctaggc
    16861 ctctcatccg ataaataaga ctcatacata aataaccgtg ctatttttat ggtgtgctag
    16921 tccctttatc aacctcggtt ttcccttgta gataatcttg ctaaagccgt cgtaatggcc
    16981 ttgcaagtgc aacttaaaag cattcaaatc atatttacca aatagcccca tctgttcaga
    17041 ttttgtgaaa gtattttcca tgcaggggat tttcccgcta ggtttttcaa cagttctttt
    17101 atctagaaaa tcgtcctgct catcgacata cactaagatt actctatctt tatagatcat
    17161 tgtgtatctc ctaaataaat cttgctaccc ctttgcctga atataccttc ccaatagcag
    17221 cgcttctgag tgttgattca tactctttaa ggtaactgtc ccacttaaaa gtctttcctt
    17281 cttcgctatc ttcaacggtt ccttctgaat taatcctatt aaaccgttta atagcaacat
    17341 cacggacaat aaacctcaat ctatcaggaa ttttggtgat ttcagtttct gagtattcat
    17401 taagtttagc tagcacacgc tctttacttt cagatatagc aagggtgatg agctcatctt
    17461 gcgcaccatc atccttggaa atacctataa agagtttgat atcgtcaata agttgtttat
    17521 cgcccatata aatagccttt aaccaccaat gccgggtaca gcagcagctt cgattgttgc
    17581 ctctacaacc ccttcaggaa tttcagcaaa cagcacattt gccccaaaga aaacagattc
    17641 ataggtaaga ttagaaagct gacgattacg agctgcagca attaaacctg tctcatcagt
    17701 aaaatcagca aacaaaccac ccaagtctcc gcctttaaca tttaaagatg caaaaactag
    17761 attctctaca gccgttgagt agattttacc ctctggcaca gatggcataa caatcacgtt
    17821 ttgcataccc aaaaagttct taagcaatgt cattccaaaa acattagaag catccgcacc
    17881 tactttagta tctccaagat agttggctac gtctaaagga gagacaaaag aaacaagcgg
    17941 ggaaccctca aactcattaa aagtagctag cttagcccat gatgcagaca gcgctttttg
    18001 aaggccaacg cctttaactt ttgttggttt tgttttgagg aatgtaaaga atgcatcctt
    18061 aattccattc tgaagctcac gcataatgcg cttatctgct tcagtaatag cacgagctgc
    18121 gccatggcga gcaattgact cagctgtagt tgcacgacgt ttcttgaacc acttcactgt
    18181 atagtcttta tctttagttc gagtaacctt agacagaggg atggtttccc cttctccagg
    18241 atcagtttga tctaaagtca cttcccactt ataggtctga atttttagat cgttagttaa
    18301 tgtttcacga cgagtaaccc ctagcaattt tagtaaatca ttaatatttt tggaaaactt
    18361 gttaacaaaa tcaattgatt taatatctcc taagtccgcc atagtgttta aatttttttc
    18421 agccataata ttcctctctt aaaataagtt acgattctca gcaattaaac gcatacgttc
    18481 gtcatcatcc tctattgcca tgatgtcagc cttagtcata ccgaccgagc cgtttccagt
    18541 tcgtggtggc ttctgggtta aacgatcgtt aacacgtttt tcgacagctt tatcaaaaat
    18601 agtttgtaaa ttatcaatat tggccttaac ctcttctgca gtagtggtta aaacaatatc
    18661 aataaaatcc aatggcaatc ctttctccac aagcagggaa tgcgtttcaa tgcgcatctc
    18721 gcgctctgct actgcttttt cacgctctgc gatagcatct agacgttttt gttcctcctc
    18781 tttagcgcgc tcatcttttg acaacttggc caaacgttca ccctctgtac gagctttttc
    18841 aatagcttct gattgttcag attcccattt agtgcgttcg gcagccatca tttttgagat
    18901 gtctgcgcga gtaaaagttc gctcatgttc ctgcttagga tgttcaacag cttctttttg
    18961 agtgtcgact tgctcagttg tttctgttgt tacattctct tctgccataa ctttctccta
    19021 gtggttacgc caccaaccga tagtctagct ttacgtcctg cgacgaaaca gtgtagcttt
    19081 tagtgtcatc aacaaagttt ggacacaata aaagccgtat tgctacgact ttgatttcta
    19141 aaggggtcga attcgtttaa aatttatttt ccccacttac gcttataatt tttcttaatg
    19201 tagttaacat caattgcaat gtttgtaata gctgcttgat tatctaaagt agcagcttta
    19261 acagacgcaa actcttcgtt tgttgccaga gcgttccgct gaacaattga tttcaactcc
    19321 atgatttctt tgttttgatt tttaattgct tctgcttgca tggcattctc tgcaacaagc
    19381 atcacaacca ctgtttccaa tttacgtttt ttcttaatgc gcttattcat gtttatccta
    19441 cctttttcaa ttctgcaata attgacttaa ccgctattgc tgcaatgcca acaatcaata
    19501 tgagcaccaa tacacctagt gccactaata ccatttgcca aataaacata ttttcctcct
    19561 tgatagtttt aatagggtga tgtataattg agataaagaa ggatgatggt ctaacgccca
    19621 cgaagcagtt tactgtggag gcggtggggc atcatccttc tttttctaat acagctaata
    19681 cctcatcttt atttttgata attgatatat caagacccct acgatctatc atataaattt
    19741 gttctaactg ccccattatc tcttcaaatg ataaaggggt ttttgttata tcaaaaatga
    19801 tattagttgc ctgctttttt gcttttcgta gattgccatc aatgacgttt ttacccgaac
    19861 ctgtgatttc ttttagatca aaaggaactc tatcaactaa ataatcagga gtattgatat
    19921 gttcagggga attaactctt ggcaccatgt caacttgcaa tcctgtcttt ttagataacc
    19981 aattagcaac tctatattca taattcgagt gatcaagaac aacattatgg ccatctactt
    20041 tgtaaggagt gccatttttt acatactcat ttagtagtga cagttgtggt ttatgcccat
    20101 ttccatctat ccaatctgag gtgacatcct taaaatactt agtgctttta tcatcaattg
    20161 gttctacttc aatgcttagc tcatcttcat caggaataag ggttgttctg cagttgaaat
    20221 gataaggtgc tgcattaatt ccaggcttta gctcagataa tagctttctt ttgttttctt
    20281 tagcgatttt acgacatatc tcagttgtcc tgtcatcacg cctaactaaa tcacgataat
    20341 acttaagacc tgcatccaag tagcgcctag cggtagcatt attaatcacc atagttccat
    20401 cagttctgat tagtgtttca gccctgtgat tggcaacatt aaattgctta gctaaatctc
    20461 tggctatcgc cctaggatgc tcgccacgaa caaaaccttg ttttaatttc ttttggagat
    20521 tcttgacaag attgtcagta ttgccccaca gctgttctga atagttataa ccatcaaacg
    20581 gggttctaac cagttcttct aaaactggac cattgattgt ccctgaccgt ccacccattg
    20641 cttttttata agcatatgag gcagcttttt ttaaatgatt ttcaaatgct gaatcaagta
    20701 caccttttag tatccctgcg cgataaacaa gttcaagatt taatgcatcc atccttgtag
    20761 ctcttgctga tacatactgc tcattaagtc gttttagcag ctcagggtct ttctcagctt
    20821 gtttgcgata cttgttagca ttagctacgt aatctgataa atcttcatga cgtagctttt
    20881 taacgacatc ctgataagtc attttgttct cttcagaata cttagtataa aaatcaaaca
    20941 attccttttg taactcaaaa gcctgttcat tatataactt ctgcagttct gaaaagacat
    21001 ctaaatcagc tctgtctaaa taacttagaa tatcttcttg acgcttttgc cagtaattaa
    21061 ggcttttctg ctgttggttc ttcttgacca ctagcatcac ctaccaatct aggctccggt
    21121 aaagattgct ttttatcagc ttcttctttc aaacgttcaa gctctgcttc agcgtctact
    21181 cctgtgacag tgtttaagat ttcaaagata gtctgatcgc taacaatgcc ataaagattt
    21241 tgtgcagctg taacaatttc attatcgttt tgaggaagat taggtgtgaa aactatactc
    21301 gtatcattta caaggctata tgtagttgct tcattccctt tgatggccca gatattagct
    21361 gctaagcgta agcgccgcat taagcctttt ttgaacaacc tctcttgctt ctcgcgatag
    21421 ttgtcagaag ccataagctt atacttcatt gattcaccag attgaactcc tgaaaatttc
    21481 atatcttgtg tatctggcgt aaaagtaaac ctcaaaatgt ctgcaactag tctatttttg
    21541 taggcttcgc taccggcggt atcatactct tttttgagaa agtacgcttg tggtttaacg
    21601 ccatttggat taggattatc gtctaaaatt aacacttggg cttttttaaa cccaattgag
    21661 atcgctaaac gaccattagg atttaatcgt ccgtcatcta agtagtcatt ctcatcagcc
    21721 cctgtgtaag cattaccagc tattacaagc aacgcattga ctgaatcttg ttgaaaatta
    21781 gcaagctcgg actgagataa atcataggca tcaatattat caagtacaga ctcataagcc
    21841 cctgtacgct cctcattatt agcatattca ttgactggta cacctttaaa aaaatgttct
    21901 tcatgctctt ttaagcacgt accttttgtt tcgagattat agtcttcgta ggtgtaaatt
    21961 gtgtcggaag tatatacttt gataatctgt ttgcgtttac ctgagccata atctatgttg
    22021 taaaaatgaa cggccatcaa cgaatttcgc tggtatgtat catcatagat aacaaaagtt
    22081 tgctcggctg ggagctggta gagttttact tcggtttttt tgtcatctat ttcctcaaca
    22141 gttaacagct cgtaggctct tccataaatt gataaatctg tttttatttt gacgttgtgg
    22201 tagtcctcat tgtttctgac cgacataagg tcaatagccg cctggaggtc tttattttca
    22261 tttttgtact caacgggaac accaagcata taaccttgct caaataccgt aatatattta
    22321 gcaaaatcac ttgcaatacg attatccgct gcgtatttat ctgttttagc aggtctatac
    22381 ttgatgttat tatccccaag atagtatcgc tttaactctt tcaaacgctc taattgttct
    22441 gctttaaacc ttgaaatgta attcttaagt tgatctatcc aaagttttga ttcatagtca
    22501 attgcttcaa agtcttcttg cagcataata aattgcttat tagcattctc attaaaacga
    22561 gttcctgcta aaaattgttt ttcttccaaa gtctcacctc attcctaaaa ataatattta
    22621 gcatttttca tgcgcttact tctatccgcc gactggtata ttctgtcttg tacggcatat
    22681 cttatggcgt caatgcagtg gttataactg tcaactggtt cgttgatata ctcattagtt
    22741 ttcttgtctt tcttccaagt gtaattttcg agttcttcaa tagtcttgac acacctttca
    22801 tcaacaaccc aatcatactg aagcaggtac tgaattcctt gcataacggt tccaggccct
    22861 tttgtaacat caatcattct aggaatacct aaattcctca gctcttggtt agatttcttt
    22921 tcagccgaat ctcctctgat ttcttctttg gcatagccga ggtcctttat agcatttgct
    22981 attttgtcat tggtcaaatt ctttctgaca tattcctcta tgacgtataa cttcttgttt
    23041 gcgtcatcga ttttaacatg caaaaatgcc gaagggtcat tgataaaccc atagtccaaa
    23101 ccaaaaaaag aagacaagtg tgataacttg tctttgttta atatttgctt gtcatatttg
    23161 ggaaaaatta gtttatcaag tgtagcaaac tggccaagag catatatttt gtagtaagct
    23221 tcattcctat cggctagttc ctcaatattt tctctcgtga catcatctaa gaagcggttg
    23281 tctttataag ttgtttgata gacaactgta ttcttaggtg tcttaacgaa gaaggcttta
    23341 taaacccagt ttacttttga cacagggtta aacatcaagt atatttgctt ctctagatgt
    23401 ttcttatctc ttaaacgcaa agtcaactgc gtataatcat caagcgtaaa ctcactagct
    23461 tcttccatga cgacatcaga tatcccctta attgacttaa tcttctcagg gttatccata
    23521 cccttaaaaa tgaattccga gccattcggg agcgttattc taaaagccga catatttatc
    23581 ttacatttat ccaagatgcc gaaatacgac aaattagaca tgatatcagc aaatacagag
    23641 tctctaacgg ttgcaccgac ttttctgaga actaatatct ttctgggatg tttgaattta
    23701 gggttaagtg cttttaaaat tatcttttga aaaacaccgt gagactttcc gctagacgcc
    23761 ccaccataat gaacttccgt gaagttgcta tagttgtaaa gtttgtcgta gatatgtttg
    23821 ttaaaaactt tgctaggata cttgattacg atattaattt tagggcgctg tttaatcgtc
    23881 atcccactca cctacgttaa tggttacatc tgagctgaca tccatttcaa ccttgtcagt
    23941 gaataatctg taccgcttac ctagtagctc agctgccttg attctatctt ttgcaccaac
    24001 atcgatgtca actatcttct ggccaaactc tccaacgcta atgagcgtct tttcttgttg
    24061 gtctcctcgc ataattgaag tgagatattg taggacttct tcttgcgtag caatcttttc
    24121 agattcaagt ttttcaagcc gctcgtctat ataagcttta atgtcaggtt tggtcaagtt
    24181 ttcttgacct attgaccttg ctgtcttttt actataccct gctttaatag cagctgctgt
    24241 cgcgttagct gagatgatgt actcatctgc aaaacgcttc tgttttaggg ttaatttact
    24301 caattttcca tcacctccaa gcataacaaa aaggcaagac actatttgcc ttacctttaa
    24361 actcatacta tcaatttatc atcaaaaaga tgacaattcc atacattttt gtgtcacatt
    24421 cctatttttt tggagaatat ttctagaatc cgctctcttt tgcggtaaat agacttacgt
    24481 gacagatgtc ttgtataggc aatttcttcc caagtgttac ttgaaccaac accccaccta
    24541 agattaaaaa tatcagttag ctcttcatcc aaaagattta gcgttgcaat aactgcttct
    24601 ttgaaattgg atagaccctt tagttcccta tctgaatccc accttgcaac cacatcctca
    24661 gtaacttttg aaacaaaatt tgctcttcct ccaccgatat ttttatctac ttctgtattc
    24721 atatcagttt gtagctcaag ttttcgaagt gcaatcttgt tatcaataaa acgataatca
    24781 aacaaccatt catcaaaagc ctttagctgt gcattagata atctactcat cccgttacct
    24841 ctttatgaat aattacgtga gaaatatttt gtttgggtat aataactgcg ttgttttttc
    24901 catttagagc aatgacatcg ttatttttca ttgcgccaat tacttcatca atacaaattt
    24961 caccataatt agaaacgctc ttagtaggac cttgctttaa aaaaaattca attttcattt
    25021 gctacctcca taagattttc accgcaaaaa ggacagtgtt tctgactata tgtttcattt
    25081 ttacactctg gacaacatgg tactgcataa gttgttaaat cacctacagc atctatcccg
    25141 ttttccattc tatggattat attcatacct acccccccat ttcctgtcaa ttctgcaatc
    25201 cgtttgtttg cgatattaaa gtaatcttta tttagctcat atccaataaa gtctctcccc
    25261 gtcagtagac aagctactcc tgttgatccg ctgcccataa aaggatctag gacaacagcc
    25321 ccttttgttg tgtgtcgcgt aatgatgtcc ttcatcagag ctactggctt ttgtgtcgga
    25381 tgctgtgttt tttctgctcc tgccacaact ggatatctgt attctggcct atcgtatttt
    25441 tcagatttac gattaaatac ccacttggat ttttttcgga cgacccatac cccgtactcg
    25501 ctatctgtaa tataccttct atctctgttt ctgggcatag ggttatcttt tacccaccta
    25561 aaaatatcct ttactactaa cccatttttt tcacaatgtc ttgcaatatc tcctaaattt
    25621 ttccaatcgt tgaagattat catgccaccg tttttagtta atttttgact tgcaatgtca
    25681 atccaactca gtaaatcaaa acctttatcc caatcaccaa aatctatacc tgttcgcccc
    25741 atggtagcaa agttattttt tactgatatg ttgtatggtg ggtccgttat caccatgtcg
    25801 atcaatccat cagttaactc cgctagtaat tctaagcaat ttccgcattt tatttccatg
    25861 tgttttctta ccccccattc cctgtcaatt ccgcaatccg ttttgtctgt ctagctctat
    25921 cctcactcgc acgtttaagc tgcttttgtg tcctgcttag ctgtgtccgt aatcctgtaa
    25981 tttgcggctc atagtggttt tgtaaggcta tacttatcat cagtaacata ataactgctg
    26041 tcattaagac ggcaattaca ttagactgca tatacaatct atcatctttc cgctttatct
    26101 cttctagcag cggttttatt agttcttctg tcattttttc cactccctag tatatttttc
    26161 tttaactgtt gcttcgcaag aattccaaaa cttcaacatg tccgcttttc gcgtaaaggt
    26221 tttctcttca aactgaggtt ttgcctcaaa attcttttct ctacccgtgt agattctaac
    26281 gacatattct tttttcatct agactcctaa ctgcgcctta actgcttcga gtaaggcgtt
    26341 ctgatttttt tctttgcctt gtaaaatcct aagtactttt tcatcaactg tattttctgc
    26401 aacaatgtgg tgcacaataa cgggttctgt ctgcccttgt ctatctaatc tggcattagc
    26461 ttgctgataa tattcaagac tccacgttag cccaaaccaa acaataatat gcccgccttt
    26521 ttgtagatta agcccatgcc cagctgattg agggtgacac agaagaattg gtattttccc
    26581 ggaattccac ttgtcaactg acgtcaactc ttcagcctga gggaatcgtt tcttaagtct
    26641 ttcaaaatca tgttgatact gataaaaaac taagattggc tggccttggc tttcttctac
    26701 tatgtcctca agcgcgtcaa gtttgtcatc gtgtatagca actgttgatt tatcatcatc
    26761 atagatagca ccattagcca tttgaagtaa tttattggcc aagaccgcag agttagccgc
    26821 agatatttcc ttatccttaa actccaacac caaatcagct tcaagctgtt tgtaagcttt
    26881 catattagat aacttaactg atacaacgtt gttggttcgc ggcggtaact tgagatagtc
    26941 tttagctttc atgctgacac agatgtcctc aatcttgtta tagatttctg cttctgcgcc
    27001 atccctaagc gcccaactgt aaatgattgg accattacgc ttatcaggaa caaaatactt
    27061 gtctttaaat cgagtctggc tagtctcaag cctgtcgcct ctgtccatca gataaatctg
    27121 cggccacaaa tcaatcaaac tgttaggcgc tggggttcct gttagtccta caaggcgttg
    27181 gactttcggt ctaacttttc gcaaagccct aaaccgtttt gacttactag acttaaagct
    27241 tgacagctca tcaataacca caaaggtaaa cggccattta gtcttgtagt attcaacaag
    27301 ccaggtaaca ttctcacgat taatcaaata gatatcagct tctgtttcta acgcctcaat
    27361 tcgttttccc tcgctcccca aaactttaga gtaggtgaaa tcaaaatgcc atttctcaat
    27421 ctccgtaggc cacgtttctt ccgccacttt tttaggggct acgattaaaa tcttatgatc
    27481 ctcggaaaaa atattttgaa tctcatctat cgccgatagt gttgtcagcg ttttaccaag
    27541 gcccatgtca agtaaaaggc cgcaataagg gtgctctact atccatgtct tagcgtattc
    27601 ctgatactcg tgcagtctca cacccagttc tccatttctt ttaaggccat gtccactgat
    27661 tcgtaggagt caacaaccca aacatgctgc ccagcctctt ttattttttt gtgcattgca
    27721 acttggctgg gtcttggttt tttaccaggc gctttgacct ctacaaaaaa ggttcccgta
    27781 ttcatgacaa caattctgtc aggcactcct atcgtccctg gactagtaaa ttttaaacac
    27841 agcccttttg ttttcttttt caaataattt tcaatatctt tttcagtcct catccttcct
    27901 cctttggtca ataaaggtca gggttaccgt ttttttcaac ttactttctc ttttttatat
    27961 atgtgtttta tatatgcctt attttatata tatttatttt
//
LOCUS       DAUGQX010000026        26193 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUGQX010000026 DAUGQX010000000
VERSION     DAUGQX010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26193
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.026"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            60..278
                     /locus_tag="VIA51_001056"
     CDS             60..278
                     /locus_tag="VIA51_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683001.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFYKLYNVSIDYLLGQTDYPYRFHNK"
     gene            complement(349..492)
                     /locus_tag="VIA51_001057"
     CDS             complement(349..492)
                     /locus_tag="VIA51_001057"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683002.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            579..766
                     /locus_tag="VIA51_001058"
                     /pseudo
     CDS             579..766
                     /locus_tag="VIA51_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775620.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            1468..1851
                     /locus_tag="VIA51_001059"
     CDS             1468..1851
                     /locus_tag="VIA51_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ8683003.1"
                     /translation="MKVHTTLEKDENGNWYRKDQTKTPAGERLIELDDVTIVVLENWR
                     RNQVVNTDTDFIISRFGEPFCKSTICRVIKHKAQSIGVPVITGKGLRHSYASYLINVL
                     KKDILYVAKCMGHADKSTTLNTYSH"
     gene            2114..3349
                     /locus_tag="VIA51_001060"
     CDS             2114..3349
                     /locus_tag="VIA51_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8683004.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDHRYPGSALEEENMLSAQDVAIVTMHLLEDFPEILEITKQTEVDFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRLITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQVKELPISVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(3466..4428)
                     /locus_tag="VIA51_001061"
     CDS             complement(3466..4428)
                     /locus_tag="VIA51_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8683005.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSRFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEMGSAANLTLKQMKEMKQVGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            4760..6037
                     /locus_tag="VIA51_001062"
     CDS             4760..6037
                     /locus_tag="VIA51_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8683006.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYANIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLQDRYP
                     RLTPDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRQYWEKHIEKSVLLTH"
     gene            6066..6650
                     /gene="folE"
                     /locus_tag="VIA51_001063"
     CDS             6066..6650
                     /gene="folE"
                     /locus_tag="VIA51_001063"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEQ8683007.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            6659..7459
                     /gene="folP"
                     /locus_tag="VIA51_001064"
     CDS             6659..7459
                     /gene="folP"
                     /locus_tag="VIA51_001064"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEQ8683008.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            7466..7825
                     /gene="folB"
                     /locus_tag="VIA51_001065"
     CDS             7466..7825
                     /gene="folB"
                     /locus_tag="VIA51_001065"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEQ8683009.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            7822..8322
                     /gene="folK"
                     /locus_tag="VIA51_001066"
     CDS             7822..8322
                     /gene="folK"
                     /locus_tag="VIA51_001066"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEQ8683010.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            8472..9359
                     /gene="murB"
                     /locus_tag="VIA51_001067"
     CDS             8472..9359
                     /gene="murB"
                     /locus_tag="VIA51_001067"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEQ8683011.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTPSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHTGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            9405..10559
                     /locus_tag="VIA51_001068"
     CDS             9405..10559
                     /locus_tag="VIA51_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683012.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGFENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            10543..11337
                     /locus_tag="VIA51_001069"
     CDS             10543..11337
                     /locus_tag="VIA51_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683013.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            11334..12110
                     /locus_tag="VIA51_001070"
     CDS             11334..12110
                     /locus_tag="VIA51_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683014.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGIFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            12103..13176
                     /locus_tag="VIA51_001071"
     CDS             12103..13176
                     /locus_tag="VIA51_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8683015.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(13231..13896)
                     /locus_tag="VIA51_001072"
     CDS             complement(13231..13896)
                     /locus_tag="VIA51_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8683016.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRTQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKVFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(13877..15418)
                     /locus_tag="VIA51_001073"
     CDS             complement(13877..15418)
                     /locus_tag="VIA51_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8683017.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNYLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            15579..16910
                     /locus_tag="VIA51_001074"
     CDS             15579..16910
                     /locus_tag="VIA51_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEQ8683018.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTDFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMSPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            16941..18107
                     /locus_tag="VIA51_001075"
     CDS             16941..18107
                     /locus_tag="VIA51_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEQ8683019.1"
                     /translation="MKNQLGQLALEQAKTFGGKLEVQPKVDIKTKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(18190..19239)
                     /locus_tag="VIA51_001076"
     CDS             complement(18190..19239)
                     /locus_tag="VIA51_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEQ8683020.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCQDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVKPGDNVCIVGAGPVGLAALLTVQFFSPANIIMVDLSQNRLEAAKTFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            19475..20206
                     /gene="aphA"
                     /locus_tag="VIA51_001077"
     CDS             19475..20206
                     /gene="aphA"
                     /locus_tag="VIA51_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEQ8683021.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            20384..21916
                     /locus_tag="VIA51_001078"
     CDS             20384..21916
                     /locus_tag="VIA51_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEQ8683022.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVVVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPDYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            22079..22693
                     /locus_tag="VIA51_001079"
     CDS             22079..22693
                     /locus_tag="VIA51_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEQ8683023.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     VEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIKSYI"
     gene            22852..24000
                     /locus_tag="VIA51_001080"
     CDS             22852..24000
                     /locus_tag="VIA51_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8683024.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            24049..24729
                     /gene="radC"
                     /locus_tag="VIA51_001081"
     CDS             24049..24729
                     /gene="radC"
                     /locus_tag="VIA51_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEQ8683025.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(24731..25426)
                     /locus_tag="VIA51_001082"
     CDS             complement(24731..25426)
                     /locus_tag="VIA51_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEQ8683026.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(25436..26080)
                     /locus_tag="VIA51_001083"
     CDS             complement(25436..26080)
                     /locus_tag="VIA51_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEQ8683027.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT         7978 a         4389 c         5435 g         8391 t
ORIGIN      
        1 aggacaatta aacatttttt aatcaaatct cctttatact gatattagga gaatgttaga
       61 tgtatccgcg tattaggaat ttgagagaag ataacgattt cactcaaaag tttgttgcaa
      121 atttactttc cttctctcat gcaaattatg caaaaattga gagaggagag gttgccttaa
      181 tggcagatgt tcttgtgcag ttttataaac tctataacgt cagtattgat tatttattag
      241 ggcaaacaga ttatccgtat cgttttcata ataaataaaa gtctcgcctt gatttgttca
      301 ttgacaactg aataaaccga ggtgggactt tcttgtttgt cgagcaattt agtgagatac
      361 gccgtgatag gagcgataat tattagctat aaaatagagt ggttctctat ctgccatgac
      421 cacaaatagg gacaatgata cttctgaacg ttcaggctgc cagcgtaaaa ggccagtggg
      481 tgagattccc atgagtgatt taaccagtca tacccacgga ggttgtaatt tttttgaaag
      541 gagtggaggt gtgaaaatag taacatataa aaagcttgat gaatattggt tttctcgaac
      601 atactgcaag aaatattatt agagaagcaa aaagaatagc tataaaaaag ttgaagaagc
      661 tcgcgaactt gaacaaaatg cggtacaatt aagtaaatcg ccctttgaca atagaagact
      721 tggtattgct cctaaagatg aagaaagttt agaaagtgag aattaaagat gactataaaa
      781 aatcaaaaaa agtacaaagg tgtttattgt gataagaatg ggaagatatt ttatcaagct
      841 gatcttggtg tagatccagt aacaggtaaa cgagttcaaa agaaagccag aaagaattag
      901 tatggaaagc catttggtac aatgaaagaa gcgtatgatg aactggttcg gattaggtat
      961 gggtttagta ataatcttag tattgaaaat gacaatatat cgtttgaaaa ctatatgaat
     1021 actatttacc taagagcata taagcaaaag gttcaggctg taacttatga aatagcctta
     1081 ccacatcata agttatttat tcagtatttt gattctaaac ttttaaaggg aataacagct
     1141 tgagattgtg aatcttttag tttacatatt attgaaaatt atgcaaagaa tttatggtcg
     1201 cgattcaaag cttgcatggg gtatgctgaa aggttagact atatttcaaa agtgccatgt
     1261 aaggctttgg ataatcctaa agggaaacat cccgacactc cattttggac ttatattgag
     1321 tttcagaatt ttataaaatc gtttgatttg caagattatg aagagctaca aagatttaca
     1381 actatttggc tatattatat gacaggtgtt cgtgtaagtg aaggtttatc attatgatgg
     1441 gaaaatatcg atttcgaaca aaaattcttg aaagttcata caaccttgga aaaggatgaa
     1501 aatggaaatt ggtatcgtaa agaccaaaca aaaacgccag caggagaacg tcttattgag
     1561 ttagatgatg tgacaatagt agtattggaa aattggagaa gaaatcaagt agtcaatact
     1621 gacacagatt tcattatttc acggtttggt gaaccatttt gtaaatcaac gatttgtcga
     1681 gttattaagc acaaagctca aagtattgga gttcccgtaa taactggaaa aggattgcga
     1741 catagttatg cttcctatct tattaatgtt ttgaaaaaag acattctgta cgttgcaaag
     1801 tgtatgggac atgctgataa gtctacaact ttgaatacat atagtcactg atttaatgca
     1861 ttagataaaa cagtatctga agaaataacc caaaatgtaa taagttcagg attagattcc
     1921 attttatacc aaaattcctg ccaaataact aattgatata acgaagctta ttatatcgcc
     1981 catataacag gatgtgttat tgttacaggg tacttgcttt atgagcttgt ttaagctact
     2041 aaaggtgtgt gccactatac ttccttccaa atttctgaga atttttgtta taatagtaac
     2101 tatgaaagat ataatgataa aaaggtgggt tatccttttt tttatggtat taacttgttc
     2161 agggtttggt aaaacagttc tcgcagctga ttttcaagtg ggagcagaac atgcgattgt
     2221 cgtagaggca gactctggga gagttctgta tgagaaagac gctaagacgc cagatgctat
     2281 tgcctctttg accaaattgg tgacggctta tctggtttta gataaggtta aatcaggcca
     2341 gctgcaatta tcagatcaag ttaatctctc agattatgcc ttcgagttaa caaaagatag
     2401 gtctttaagt aatgtacctt ttgacaaaaa aacttattca gttcaagacc tgttgacagc
     2461 tactttggta gcaagctcaa atagcgctgc tattgcgtta gccgaaaaag tggcgggctc
     2521 agagcttcat tttgtaaatc aaatgagaga acagctatct cattggggga ttacttctgg
     2581 taaaatcctc aacgcttcag gactgccgaa tgaggtgcta aaggaccatc gttatcctgg
     2641 ttctgcgttg gaagaagaga atatgttgag tgctcaggat gttgccattg tgacgatgca
     2701 tttactggaa gattttcctg agattttaga gatcactaaa caaacagaag ttgattttgc
     2761 tggtaattct attaaaagtt ttaatcaact cttaccaggt atggctaagg gtagagcagg
     2821 agtggatggg ctaaagacag gaacgacaga tttggcaggt cattgccttg tggtaacttc
     2881 tattgaaaat ggtatgaggc tgattaccgt tattctaaat gctgatggat ctgataaaaa
     2941 ccaaaacacg cggtttgagc aagcaaatcg cttgttggac tatgtggcta gaacttattg
     3001 tcgtcgtaag attcttaaaa aaggaagtct tgtctcggag cgatcgctcc ctattcaaga
     3061 tggccaagta aaagaactac cgatatctgt tgccgaagat gtaaccatca ttttgcaaca
     3121 gggtgaacaa gttcccaaac ctaaacaatt tatgatatca gagacttctt tattagcacc
     3181 gattactaaa ggtgaagtgg ttgcttattt gacgtctcca agaataacag atcagtcagt
     3241 gaggtattta aaggaaccta agcgtattcc tcttaaagct agccaatctc taaaaaaagc
     3301 ctctgactta cagctgtggt ggcgagattt tcttgaaaaa agacgttaaa gataagaata
     3361 aaataatttt aaaacaatca aaaaaagaca gttatgaaag aattttttca taactgtctt
     3421 tttagtttac agtgagtatg atttggaatg ataaaaaaat tgatgttatg gttccattgt
     3481 ttgtaaaaga ttttcaggac tcatgtttgg gaggatacga atccggttaa gagaaagaag
     3541 tccattagcc gcgctagcta ttccttcgtt agtggtaaca cctaatttat agttaagtct
     3601 agctgcaatt tgtaaggtag tgtcattata tctaccagat ggataagcaa tggcaatagt
     3661 gttttggttt aattgcttat caagatagtc ctttgaatct ttcatttcag ttgtttgaac
     3721 atcaggacta gcctgctcta gatcaggatg attcactgta tgatcttgga aagacatacc
     3781 gacttgtttc atttctttca tctgcttaag agtcagattg gcagcgcttc ccatttcggt
     3841 tagtcctgta ataacattat tggtggcttt agcatcatat ttttttaaga ttgggtaagc
     3901 aacattgtag aaatcaatca tactgtcatc aaatgttagc catacaactt ttttagcagg
     3961 caattcatta tttgaaagag cgcggtagac ctcttcagga ctcaaaaaat agtagccctc
     4021 gtctttcatt ttttgaagtt gttgatcaaa gagatctggg ttgacaatca aattagcatt
     4081 agccgtctct tcaggggaca ttacatgaat agcatgatac attaaaattg ggatcttgac
     4141 aggtgtttct tgcttggtcc aagtcaattt agaatgggcc tttttttgag attttgagga
     4201 atcgaaatga gtcttcttaa gttttgtcgt ttcttttttt gccgtctttt tgtgatgaaa
     4261 aagacttatt ttaggtacaa atcgagagac atctgacaag ccgaatttgt tagacccttg
     4321 atataaatag aaaatgaggg tcaaaccaag aatgcaggca aataatagta taaggttaat
     4381 gagagtgaag gcttttcttt tttggcgccg tttatgtcta ttgttcatta cttgctcctt
     4441 tttttgatat aagtacctct attgtaacat tttttagaga aaagaaggct tgaagtcagc
     4501 cttttttctt gttttttgga agaacgtgta ttaaggagta aaaaaattat tgtcacagat
     4561 aacactttag gaggtagcaa agactatgtg gggctggtat tcttatcacg taaaaaaagc
     4621 aatgaagata aaagtgtagt gtactttaga acttatttga gtgtttggtg aggataataa
     4681 aaaaaagggt actactctag gttatctgct gtcacttttt tttatatatg gtatactaaa
     4741 gatagatgtg aggtatgaaa tgacttatga agagactcta gaatggattc atgatcactt
     4801 agttttcggc atcaagccag gcttaaaacg tatgctttgg gttcttggac agttaggaaa
     4861 tccccaaaaa aatgtcaagg gagtgcatat cgttggaact aacggaaaag gttccacggt
     4921 caatcattta caacacatct ttacgacagc tggttatgaa gtggggacct ttacctctcc
     4981 ttatattatg gatttcaaag aacgtattag cataaatggt cgaatgattt cagaaaaaga
     5041 tttggttatt gctgctaatc gtattcgtcc tttgacagag cgtctagttc aagagactga
     5101 ttttggagag gtaactgaat ttgaagtgat tactttgatc atgttcctct attttggtga
     5161 catgcatcct gtagatattg ctattattga agcaggcctt ggcggtcttt atgattcgac
     5221 caatgttttt caagcaatgg ttgtggtctg tccctcaatt ggtttagatc accaagctat
     5281 tttgggcgag acttacgcta atattgccgc ccaaaaagct ggtgttttag aagggggcga
     5341 gacccttgtt tttgccgttg aaaacccgtc agctcgagag gtttttttaa caaaagctga
     5401 gcaggttggt gcttcaatct gggaatggca agagcagttt caaatggctg agaacgcatc
     5461 tggctatcgt tttactagtc ctttaggagt tatttcagat attcacatcg ctatgccagg
     5521 acaccaccaa gtgtctaatg cagctttagc tattatgact tgcttaacct tgcaagaccg
     5581 ctatcctagg ctaactccag atcatataag ggaaggtcta gcaaatagtt tgtggctagg
     5641 ccgtaccgaa ttattagcac caaatctaat gattgatggg gctcataaca atgaaagcgt
     5701 tgctgctttg gtagccgtct taaaaaataa ctacaatgat aaaaagcttc atattttgtt
     5761 tggtgcgatc gacaccaagc ctattgcaga tatgttggtt gctcttgagc aaataggtga
     5821 cttgcaggtt actagctttc attaccctaa cgcctatcca ttggaaaaat acccagaacg
     5881 ttttggtagg gttgctgatt tcaaagattt cttggccttg cgtaagcatg ctaaagcaga
     5941 tgactttttc gtgattacag ggtcactata ttttatttca gaaattagac agtattggga
     6001 aaaacatatt gaaaaaagcg ttcttttaac ccattaaaaa agagaaaatg aaaaggaaaa
     6061 aactaatgaa aagggaaaga ctaatgtcta ttaataagga aaaagcagaa gcagccattt
     6121 atcagttttt agaggctatt ggtgaaaatc caaatcggga aggtcttctt gacacgccta
     6181 aacgggttgc taaaatgtat gcggagatgt ttttgggact gggaaaagat cctaaagagg
     6241 agtttacggc tgtctttaaa gaacaacatg aggatgtggt gattgtcaaa gacattagtt
     6301 tttattctat atgtgaacac cacttagttc ctttttatgg caaggctcat atcgcttact
     6361 tgccaagtga tggtcgagta acaggtttga gtaaattagc gcgagcagtt gaagtagcta
     6421 gtaaacgacc tcaactccaa gagcgtttga cctctcaaat agcggatgct ttagttgaag
     6481 ccctcaatcc taaagggact ttagttatgg tagaagcaga gcacatgtgc atgaccatgc
     6541 gaggcatcaa aaagccaggt agtaaaacca ttaccaccac tgccagaggc ttatataagg
     6601 aaagtcgtgc tgagaggcaa gaagttattt ctctaatgac aaaagattag gagaacttat
     6661 gaaaattgga aagtttgtga ttgagggcaa tgcggctatc atggggattt taaatgtgac
     6721 tccagattct ttttcagatg gggggtctta cactactgtg caaaaagcat tagatcacgt
     6781 tgagcaaatg attgctgatg gggctaaaat catcgacgtt ggtggagaat caacacgtcc
     6841 aggttgccaa tttgtaagcg ctaccgatga aattgaccgg gtggttcctg tgatcaaggc
     6901 catcaaagaa aactatgata ttctaatcag cattgatacc tataaaaccg aaacagctag
     6961 agcagcttta gaggcgggtg ccgatattct caatgatgtt tgggcaggtt tgtacgacgg
     7021 tcaaatgttt gccttagcag ccgagtacga tgcgcctatc atcttgatgc ataaccaaga
     7081 cgaagaagtt tatcaagagg taacacaaga cgtttgtgat tttctaggca atagagcaca
     7141 agcagctctt gatgctggcg tgccaaaaaa caatatttgg gttgatccag gatttggatt
     7201 tgccaaatct gttcaacaga atacggagtt attaaaagga ttggaccgcg tctgtcagtt
     7261 gggctatcct gtcttgtttg gtatttcgag aaagcgtgtc gtagatgcct tgttaggcgg
     7321 caacaccaaa gctaaagagc gagacggagc gacagcagcc ttgtctgctt atgcccttgg
     7381 aaaaggctgt cagattgtac gcgtacacga tgtcaaggct aatcaagaca ttgtggctgt
     7441 gttgagccag ttgatgtgag gacttatgga taaaatcgta ttagaaggtt gccgttttta
     7501 tggctaccat ggagccttta aagaagaaca gacccttggg caaatttttc tggttgattt
     7561 agaattgtca gtcgatttgc aagcagcttc tttgtcagac caattaacag atacggtcca
     7621 ttacgggatg gtgtttgata gtgtccgtca gttagtggaa ggggaaaagt ttattttgat
     7681 tgaacgttta gcaggtgcga tttgtgaaca gctttttaac gaatttccgc ctattgaagc
     7741 catcaaagtg gccattaaaa aggaaaaccc accgattgca ggccactata aggcagttgg
     7801 tattgaattg gagagacaga gatgaccatt gtttatttaa gtttaggcac caatatgggg
     7861 gaccgagcag cttacttgca aaaagctctt gaggctttag ctgacttacc tcaaacacgg
     7921 ttgcttgctc aatcatccat ttatgaaacg actgcttggg gcaagacagg ccaggctgat
     7981 tttctcaata tggcctgtca attagataca caattaaccg cggctgattt cttaaaagaa
     8041 acacaagcta ttgagcaatc tcttggtcgt gtgaggcatg aaaaatgggg atcaagaact
     8101 attgacattg atatcttgct atttggagaa gaggtttatg acacaaagga attgaaagtg
     8161 ccacaccctt atatgactga gcgtgctttt gttttaatcc ccttattgga attgcagcca
     8221 gatttaaaat tgcctcctaa tcataagttt ttaagggatt atcttgcagc tttagatcaa
     8281 tcagatatca cactcttttc agctcaacag acagagttct agactctgtt ttcggagtaa
     8341 tgcctgctat aagccaatcc ataaagtttt gccaaattca tcgttatttt ttctaaaatt
     8401 tgatataata gtatcggctt tatgccgatt tttttacgtg tataagaagt gataaaagaa
     8461 agaagataac tatgataact gaacttcatg ggattgatat tcgagagaat gaacccctaa
     8521 aacattacac ttacactaag gtaggtggcc cagcagattt cttggctttt cctagaaatc
     8581 actacgagct atcacgcatc gttgcttatg ccaacaaaga aaatatgcct tggcttgttt
     8641 tgggaaatgc cagcaatctc attgtgcgag atggtggtat tcgtggcttt gtcatcatgt
     8701 ttgataagct aaatgcagtg cacttaaatg gttatacctt agaagccgaa gctggtgcca
     8761 atctgattga aacaacgaag attgccaaat tccatagttt aacagggttt gaatttgcat
     8821 gtggcattcc tggaagcatt gggggtgctg tttttatgaa tgcgggtgct tatggtgggg
     8881 aaatatcaca tattttctta tccgctaagg tgcttacccc aagtggagag atcaaaacca
     8941 tttcagctag ggatatggct tttggttacc gtcactctgc cattcaagaa acaggtgaca
     9001 ttgtcatttc tgctaagttt gctcttaaac cgggtaatta tgatacgatc agccaagaaa
     9061 tgaatcggtt aaatcacctt cgccaactaa aacaaccttt agaatttcca tcttgtggat
     9121 ctgtgtttaa gcgcccgcca ggacactttg caggtcaatt aatcatggaa gcaaatctta
     9181 aagggcatcg gattggtggt gtggaagttt ccgaaaaaca cactggtttt atgattaatg
     9241 tggcagatgg cacagctaaa gattatgaag atttgattgc ttatgtcatt gagacagttg
     9301 aaaaccattc tggtgtcagg cttgaaccag aagttcggat tattggggaa aacctgtaac
     9361 cattattgat aattaaagaa agtaccgtgg aggatttatg acaattgact aagccaatta
     9421 tcacatttaa caatgtttca aaaacatttg aggacagtgg aacacaggtt ctaaagaaca
     9481 ttaactttga ccttgaagaa ggaaaatttt acaccctgct tggagcttct ggctctggaa
     9541 aatcaactat tttaaatatt atggcgggcc tactagatgc cagcagcgga gacatttatt
     9601 tagatgggga acgtattaat gatttgccga ttaataaacg tgacattcat accgttttcc
     9661 aaaattatgc cctcttccct catatgactg tttttgagaa tgttgccttt gctttgaagc
     9721 tgaagaaagt ggacaagaaa gagattgcta agcgcgtgaa agaaaccttg aaaatggttc
     9781 aattagaagg gtttgaaaat cgttctatcc agaagttgtc tggtggtcaa cgtcaacgtg
     9841 ttgccattgc gcgtgcgatt atcaatcaac cgcgtgtggt cttacttgac gaaccactct
     9901 cagcccttga tttgaaatta agaacagaga tgcaatatga attacgtgaa ttgcaacaac
     9961 gtctaggcat tacctttgtt tttgttactc acgatcaaga agaagccttg gccatgagtg
    10021 attggatttt tgtcatgaat gaaggtgaaa ttgttcagtc gggaacacca gtggatattt
    10081 acgatgagcc aattaatcat tttgttgcta attttattgg agaatctaat attattaacg
    10141 gtaccatgat tgaagactat cttgtctcct ttaacgggaa agaatttgaa tctgtggacg
    10201 gtggaatgcg ccctaatgag cctgttgaag tggttattcg tcctgaagat cttcaaatta
    10261 ctttgccaga agaagggaaa ttacaagtta aggttgatac ccaattattc cgcggggttc
    10321 actacgaaat tattgcctat gatgaattgg gtaatgaatg gatgattcat tctacccgca
    10381 aagctatcga aggagaagtt atcggattag attttacccc tgaagatctt catatcatgc
    10441 gtcttaatga gactgaagag gaatttgatg cccgtattga agaatatgtg gaaatggatg
    10501 agcctgaaga tggattgatt aatgccattg aggaggagcg taatgaagaa aacctctagt
    10561 cttttttcga ttccttactt cttatggatt ctcttttttg ttgtggcacc agtcactctc
    10621 ttgttttaca agtccttttt tgacatagaa gggcgcgtga ccttagccaa ttatgaaacc
    10681 ttttttagct cttggactta tttgaggatg agtgtgaatt ctattttata cgctggtatt
    10741 atcacactcg tcacgctctt gatttcatat cctacggctc tctttttaac gcgcctaaag
    10801 cacaagcagt tgtggcttat gctcattatc ttgccaacct gggtaaattt attgctaaag
    10861 gcctatgcct ttatgggaat ctttggtcaa caaggaggga ttaacagctt tttaaccttt
    10921 atggggattg gcccgcagca aatccttttc acagatttct ccttcatttt tgtagcctct
    10981 tacattgagc tcccttttat gatgttaccg atttttaacg ctttggatga tattgaccat
    11041 aatgtcatca atgccagtcg cgacctagga gctagtgaat ttcaggcctt ctcaaaagtt
    11101 atttttcccc tttctttaaa tggggttagg gcaggtgttc agtctgtctt tatcccaagt
    11161 ttgagtctct ttatgttaac ccgtttgatt ggtggaaacc gggtgattac acttggtaca
    11221 gccattgaac aacatttttt gaccacccaa aactggggaa tgggatcaac cattggtgtc
    11281 gtcttgattt tgaccatggt tgctattatg tggctcacaa aggagaaaag taaatgaaaa
    11341 aatttgccaa tctttattta gcgagtgtct ttgttttact ctacattcct attttttatt
    11401 tgattttcta ttctttcaac aaaggtgggg atatgaatgg ttttacagga tttacccttg
    11461 agcattacca aaccatgttt gaggatagtc gtctcatgac aatcttactg caaacctttg
    11521 ttcttgcttt tagtagcgct ctactagcaa cgattattgg gatctttgga gctatcttta
    11581 tccaccatgt tagaggtaag taccaaaatg ccatgctatc agccaataat gtcttgatgg
    11641 tatcaccaga tgtcatgatt ggggcttcct ttttaattct ttttacatca ttgaagtttc
    11701 agctgggcat gtcttcagtt ttattaagtc atattgcttt ttcgattcct attgtggttt
    11761 tgatggtatt gccgcgcttg aaagagatga atcaggacat ggtcaacgcc gcttatgatt
    11821 tgggagctaa ttatttccaa atgctcaaag aagtcatgct gccatactta acaccaggga
    11881 ttattgcagg ttattttatg gcctttacct attccttaga tgattttgca gtgactttct
    11941 ttttgactgg aaatggtttt actactttat ctgttgagat ttattcgcgg gctcgtcagg
    12001 gaatttcctt ggatatcaat gctttgtcaa ccatcgtttt ctttttctcc atcctcttag
    12061 tgatcggtta ttattatatg tcacaggaca aggaggaaaa acatgcgtaa actttattcc
    12121 tttctagcag gagttttggg tgttattgtt attttaacaa gtctttcttt catcttgcag
    12181 aaaaaatcgg gttctggtag tcaatcggat aaattagtta tttataactg gggagattac
    12241 attgatccag ctttgctcaa aaaattcacc aaagaaacgg gcattgaagt gcagtatgaa
    12301 actttcgatt ccaatgaagc catgtacact aaaatcaagc agggcggaac cacttacgac
    12361 attgctgttc ctagtgatta caccattgat aaaatgatca aagaaaacct actcaataag
    12421 cttgataagt caaaattagt tggcatggat aatatcggga aagaattttt agggaaaagc
    12481 tttgacccac aaaacgacta ttctttgcct tatttctggg gaaccgttgg gattgtttat
    12541 aatgatcaat tagttgataa ggcgcctatg cactgggaag atctgtggcg tccagaatat
    12601 aaaaatagta ttatgctgat tgatggagcg cgtgaaatgc taggggttgg tttaacaact
    12661 tttggttata gtgtgaattc taaaaatcta gagcagttgc aggcagccga gagaaaactg
    12721 cagcagttga cgccgaatgt taaagccatt gtagcagatg agatgaaagg ctacatgatt
    12781 caaggtgacg ctgctattgg aattaccttt tctggtgaag ccagtgagat gttagatagt
    12841 aacgaacacc ttcactacat cgtgccttca gaagggtcta acctttggtt tgataatttg
    12901 gtactaccaa aaaccatgaa acacgaaaaa gaagcttatg cttttttgaa ctttatcaat
    12961 cgtcctgaaa atgctgcgca aaatgctgca tatattggtt atgcgacacc aaataaaaaa
    13021 gccaaggcct tacttccaga tgagataaaa aatgatcctg ctttttatcc aacagatgac
    13081 attatcaaaa aattggaagt ttatgacaat ttagggtcaa gatggttggg gatttataat
    13141 gatttatacc tccaatttaa aatgtatcgc aaataagcac tcaaaaaggc tggtatttct
    13201 ccagcctttt taatgtatcg acagatgacg tcaccagtac acgcgatagg ggcggccaac
    13261 ctttgtaaaa atttgttggc tgttcagttg cttattttct tctaaataag caatgtattt
    13321 acggacagag acatgggata agtgacaagc ggaagctaat tcttggatag taaaaggttg
    13381 atcaaagact ttgatatttt ccataatcca ctggaaagtg gattcagata agcctttttc
    13441 taacaattgt ttgtttttag tgtctttttt gctagtcaaa catttcagtt ggtcaatttg
    13501 ggcctgctct agttgctgat tggccaaatg ttctcgatgt gtaacaaact gttggatgct
    13561 ttcttgaaag cgttcaaagg taaagggctt gatgaggtag tcgataattc ctaaatgaaa
    13621 accatctcgg ataatattcc catcatttgc ggctgaaata ataatgactt cgcaaggaat
    13681 atgctgagta cgccatttct ccaaaaattg aatcccattg ccatctgtaa tatgaatatc
    13741 cagtaaaatg aggtcaattg cgtaatcagt aagtatgctt tgaacagctt tcatagagtc
    13801 gctggatata atgcgatcaa aaagatttag tttttcgagg taattgcgat ggataaaatc
    13861 caccatagga tcatcttcaa tgattaaaac gttcatgttg ccctcctaca taaggtgttg
    13921 tcactgagaa ctgtaactcg gttacggttt gatgttgatg gaattgggaa tttgtatcgg
    13981 tcaagagctg ttgaaaataa ggtaagtcaa aaataggctg tacccgctcc aaatcaatcc
    14041 aattgtctgt caaggtgtaa tggctgatta aatgattctg gtcatgttga atactcaaaa
    14101 cgagtgattt gggtctcagt gtggttagaa gattagtatg gataaagcgg taaatcatca
    14161 aaccattatt aagttgattc ttggtggcag aatgaggaat ctcgcttaaa acatcaatct
    14221 tgagatggac atttaattct tggtatttct cttgctctcc aatgagaaaa ctagctagaa
    14281 gaggctcctt aacaaggaca gataagctag tgagaatttc attttcgggt tccaaaatac
    14341 tgtctaaata aattttcaat tggtcataat aagcaatatc cactaagcca taaataacat
    14401 gcaattgatt catgaattta tgagtttggg cttgtagagc agaagcatag gcagtggtat
    14461 aggctagctg atccaaggta tcaatagcct taactgcttc tcgcatgaaa ataatatggc
    14521 ctcggtgatc gtttttgaca cagatgggtg aaatggctaa caagtagtct tcctcaccat
    14581 accgaaagag ttgttcatgc ccctcttgca aactaagttt tggaaaatca ggaaagaggt
    14641 aattgaaact gttgccagta ggttttccca actggcattt ccgagcaatt aatttttgtc
    14701 cagcctgatt gcagagctgt aagataccag ctttatctac cacaaatacg gcggcttcga
    14761 tttgatccaa catggcatta cgctcttcaa agagctgata aatttcactt ggttctaact
    14821 ggtgcagttg acgcttgagt cgaaaagaaa taaaactggt gaccagtaaa ctaataagaa
    14881 gacaaaggag taaagacagg gtataattgc gttttgacgt taaagccaca tcatttaggg
    14941 tagttagttt aatgccaacc gcaatagcac caatctgttt gtcaccgtca aacacaggta
    15001 ctagatagcg aagtgacttt cctaaagtgc ccttggcggt agagataacc ttttttcctg
    15061 ctagaacagc ctcctcatca cctccttgaa aaggttttcc gatatttttc gggttaggat
    15121 gggtgagtcg aatccctttc atgttcatca cgaccacata atcaaggtta tagatggagg
    15181 caatggagtt ggtataggct gttgttttag catttggttg gttgtttagg agtaattctt
    15241 taatcgcttg atgacttgct aacatttttc cagttgacgt tagcaaatgg gtttcctgat
    15301 ttttgatgga ttggtgcgta tcatgtagca taatcccgta aaatagagag gttgtgacaa
    15361 caatcataga taccaaaatc aacgataaac tggcccataa acgtagtggt tttttcataa
    15421 ggtctcctct ttattgagta taacacgata agaaatgacc tgctagctta aattaattaa
    15481 ataacttgaa aaaattaaag tagttaaaca acttaaataa actatgcttt tgacatgttc
    15541 tcttttatac tagccttatc actaaaggag gttgtttcat ggaaacaata agcaagaaaa
    15601 tgcctcaaaa agacttgtct gagcattcaa aagcatggca aaataggcga ataggctccg
    15661 ttcccttgcc tgtttatctg gttttagcta ccttaatttt agtcacaggc tggctccaac
    15721 aattgcctgt taatatgctg ggtggctttg ctgttatttt aacccttggt tggctactag
    15781 gaaccattgg agcgaccatt ccaggcctca aacattttgg tggcccagct attttatcac
    15841 tcttagtccc ttcgattttg gtttttttta atctcctcaa tcccaatgtc ttagaagcga
    15901 cgaatgtctt gatgaagcaa gccaattttc tttattttta tattgcctgc ctggtctgcg
    15961 gtagtatttt aggcatgaat cgaaaaatct tgattcaagg tctttttcgg atgattattc
    16021 ccatgttact tggaatggtt tgtgcaatgg gtgtagggac tttggttggc gtcattttag
    16081 gattagactg gcaacatacc ctcttttatg ttgtgacgcc agtccttgct ggaggaattg
    16141 gtgaaggtat tttaccctta tctcttggtt acagtgccat tacaggagtc ggaagtgagc
    16201 aattagtggc tcaactgatt ccagccacca ttattgggaa tttctttgct atcttgtgca
    16261 cggctttgct caatcgtttt ggagagaagc acccaagtta ttctggtcaa gggcaactgg
    16321 ttaaaattgg tcacagcgaa gacatgtctg atgccctaaa agacaattct ggagccctag
    16381 atgttaaatt aatgggggca ggcgttttaa cagcttgttc actttttatt gctggtggct
    16441 tgttacagca tttaacagat tttccaggac cggtgttgat gattattctg gcagccttct
    16501 tgaaatacct gaatgttatt ccccaagaaa cccaaaatgg tgccaagcaa ctttataaat
    16561 tcatttccag caactttact tttccgttaa tggcagggct tggtctactt tatatcccct
    16621 taaaagaggt tgtggcaacc cttagctggc aatattttat tgtggtgatt agtgtggtgt
    16681 taacggttgt cagtgtcggt ttttttgtct ctcgtttcct taacatgagc ccagtggaag
    16741 cagctattat ttcagcttgt caaagtggta tgggtggaac cggtgatgtg gctattttga
    16801 gtacggctga ccgcatgaat ctaatgccgt ttgcccaagt cgctacccgt ttaggtgggg
    16861 ctattaccgt tatcactatg acagctattt taagaattat ttttagttaa tccgaaccaa
    16921 taaaaagaga ggtatttcct atgaaaaatc aattaggtca acttgccctt gaacaagcca
    16981 aaacgttcgg cggtaaattg gaagttcaac caaaagttga cattaaaact aaacatgatt
    17041 tgagtattgc ctacacacca ggtgtagcga gtgtgtcatc tgccatcgca aaagataaaa
    17101 cattagcata tgacttaacc accaagaaaa atacagtagc cgttatcagt gatggtactg
    17161 cggttcttgg tctgggggat attggccctg aagcagccat gccagttatg gaaggaaaag
    17221 cagccctttt taaagcattt gcgggtgttg atgctattcc gattgtatta gataccaaag
    17281 atactgaaga aattattagt attgtcaagg cgcttgcacc aacctttggt ggtattaatt
    17341 tagaggatat tagtgcgccc cgctgttttg aaattgagca gcgcttgatt aaggaatgtc
    17401 atattcctgt tttccatgac gatcagcatg gaacagctat tgtggtgtta gcagccatct
    17461 tcaatagttt gaaacttctt aaaaaatccc ttgatgaggt atccattgtg gtgaatggtg
    17521 gtggatctgc tggattatcc attacccgta aattattagc agcaggtgct acgaaagtga
    17581 cagtagtgga taaatttggc attatcaatg aacaagaagc cgctcaatta gcgccacatc
    17641 atttggatat agcgaaagtc actaatcgtg agtttaaatc aggtacctta gaagatgctc
    17701 ttgaaggagc agatatcttc attggcgtat cagcaccagg agtcttaaaa gcagagtgga
    17761 ttagtaaaat ggcagcgcgc ccagtaattt ttgccatggc caaccctatt ccagagattt
    17821 accctgatga agcccttgaa gcgggggctt acattgtagg tactggccgc agtgattttc
    17881 ctaaccagat taataatgtc cttgcctttc caggtatttt taggggagca ttagatgcac
    17941 gggcaaaaac cattactgtt gagatgcaaa ttgctgccgc aaaaggtatt gccagtcttg
    18001 tcccagatga cgctttgagc actactaata ttattccaga tgcctttaaa gaaggagtcg
    18061 ctgagattgt cgctaaaagc gtcaggtcgg tagtccttaa atcatagaat atatgaaaaa
    18121 aaagagaaag ttatacttta aatcacaaaa taagtagaag catatttcta gcttctactt
    18181 attttgtgat tagctaatat cattatcaat aataactttc aaggcgttat ttgcaccagc
    18241 atgtttaaag gtttcataag ctttttcaac ttctgaaagt ttaaaatgat gtgtaataag
    18301 tcttgttgcg tcaatctttc cagttttcaa gacatttagt agcatttcag ttgtattggc
    18361 attaacaagt ccagtgttta aggtgatatt tttaatccat aattcatcca ggttgaaatc
    18421 aactggtttc ccatgaaccc caacgttagc aatatgccca cctactgata taattttttg
    18481 acaaatatca aatgtcgcgg gataaccaac acactccatg gaaatatcga caccacgtcc
    18541 attggttata tcgtcaatga tagccttgac ttcttcacta cttcctgaac aaatcgtgtg
    18601 tgtggctcca aatgttttag ctgcttcaag gcgattttga gataagtcga ccataataat
    18661 attggctgga gagaaaaatt gaacggttag tagggctgcg agtcctactg gaccggcacc
    18721 aacaatacaa acattatctc caggcttgac atgtgatggc aagacaccaa tttcatatga
    18781 agttggtaaa atatcagaaa gcatgacaag tgcctcatca tcaatcgtat caggagcatg
    18841 atagagacta ccatctgcat gtgggatatg gacatattct gcttgtgttc cattaattaa
    18901 atggccaaga atccaaccgc catcttgaca atgtgacgaa aggcctcgtt tacaataata
    18961 acaggtatga catgatgtga cgcaagaaat aatcacttta tctccgattt taaagttagt
    19021 aaccgcatca ccgacctcct taacaattcc aattccttca tgaccaagga ttgttccttc
    19081 tttacatgcg ggaacatccc cacctaagat atgcaaatca gttccacaaa tagtggtttt
    19141 taccaactgg acgatagcat ctgtaggctt tataatgact ggttttggtt tgtctatgag
    19201 ctgtagattt ccggttgaaa ggtaagttgc tgctttcata tttaacttct tataaggttg
    19261 agaggtaatc aaccaattca tttttacaca gatattataa tattttaaga aagggttttc
    19321 aatatttttt aaatcgatta tgataatttt ttagatcatc tttgttgaat aacttcatcc
    19381 ttattcagaa cttaaagggt actattataa gaatttgaaa ccgctttact taaaccgtgt
    19441 atttttgtac aataatgatt aaggaggttt ttagatgaaa aaagaattta ccagtatcct
    19501 gtttacagtt agtttttgtg gaatcatagc attgcctgtc gaagctagtg gccctaaagt
    19561 tccttataca caagaaggta taacggccat ttcaaatcag gcaacagtaa aattgatttc
    19621 tattgctgat atcgcgagca gtttagaagg acaaaaacct ataacggtta gttttgatat
    19681 cgatgatact ttgttattta ctagccaata ttttcagtac ggcaaagaat atataactcc
    19741 aggctcattt gattttttgc ataagcaaaa attttgggac ttggtcgcta aacggggaga
    19801 tcaggattct attccaaaag agtatgcaaa gcaactaatc gcaatgcatc aaaaacgagg
    19861 agataaaatt gtctttatta ctggccgaac tcgaggatcg atgtataaaa aaggtgagat
    19921 tgataaaaca gctaagtcac tggctaaaga ttttaagtta gacaagccaa tagctatcaa
    19981 ttatacagga gataaagctg tgaagccgta tcagtatgat aaaacatatt atataaagaa
    20041 aaacggctca caaattcatt acggagatag tgatgaagat ataaatgctg ccaaagaggc
    20101 aggtgcaaga cctattcgca ttttaagagc tcctaattca accaatcttc ctttgccaaa
    20161 agctggagga tacggagaag aggttttaga aaattcggct tattagtcaa atatttgtgt
    20221 aagaaaggaa gtaacagtaa tttctttcat caccccactg agtaaccaat agcccagtgg
    20281 gttttttggg ttacagaaat cagttctaaa aaagaatcac tggtaactta aggttgtctt
    20341 tgatacaatg gtaacagtgt atttaaaaga aagagaggac aacatggaaa accataaaaa
    20401 tgaattcacc ttttccaaca aatcaattat tgcctatgtt tggcgtggtg ttgtggttgg
    20461 tattattgct ggtgttattg ttagtttatt ccggttgtta attgaagtga cagctgactg
    20521 ggtgattgaa tggtaccgat acgctcatat caattcgctg ttgctacttc ctatactaag
    20581 tgtcagtttg ttagctgttc tttttgtagg ttttttagta aagtctgatt ctgatataaa
    20641 aggatcaggg atcccccatg tcgaaggaga actaaagggg ctaatgtccc cagattggtg
    20701 gagtgtcctt tggaaaaaat ttttaggagg aatcatggct atttctatgg gatttatgct
    20761 cggtcgtgag ggtccttcga ttcagttagg tgctatgtca gccaaaggat tagctaagtt
    20821 tttaaaatcg agtcgtttgg aaaagcgagt gctaattgcc agcggagcag cagcagggct
    20881 atcagcagct tttaatgctc caatagcagg cctcttgttt gttgttgaag aaatttacca
    20941 tcatttttcg cgtttaattt ggattacagc gctagtggct agcttagtgg ctaattttat
    21001 ttctctgaat atttttggat tgaaaccagt cttagcaatg tcagaggcga tgcctttttt
    21061 aggactcaat caatattggt tgttgctttt acttggatta tttctaggct gcttaggcta
    21121 tttatatgag atagttatcc ttaattttaa taaactttat gttattttag ggagttggtt
    21181 acatctgcca gattattttt acggtattat tatggttttt ctaattttac cgattggcta
    21241 ttatttacca cagttacttg gaggaggaca tggtttaata ctttctttat ccaatcaaca
    21301 attgcctttg atgactatct tcttttattt tattattcga tttattgtta gtatgtttag
    21361 ttatggaagt ggcttacctg gaggtatttt tttacctatt ttaactttag gtgctttggc
    21421 aggcctatta tttgggcaaa tagcttctca attaggttta ttgaaccaat cttttctttc
    21481 tctttttttg atattaggga tggcagggta ttttgcggca atttcaaaag caccactgac
    21541 aggcatgatt ttggtaactg aaatggtagg tgatttgaaa cccttgatgg ccatagctgt
    21601 agttactttt gtctcctatt tagtgatgga tttgttaaat ggacagccaa tttacgaagc
    21661 tatgctagat aagatggcaa tgaagcatcc aactaatctt gttgaaccaa cattaattga
    21721 attgactgtt ggtgataaga ttgcagggaa atatgttaaa gagttaaagc ttccagaaaa
    21781 tgtcttaatt acaacccaaa ttcaccatca aaaatctcaa gttgtgtcag gtaacacgcg
    21841 ccttttatca ggagcaacta tctttttggt cgttaatgaa gctgatacag gttttgtccg
    21901 tgaggtattg atgtaggtat taatttatca caattcggaa agttcgagct tgtcttttag
    21961 actaagtctt cgaacgtttt actgctagag tttcatctga accaaagtga aacgcttttg
    22021 atgaagtcaa gtaggctttt tgttatacta acaataaaga taagctaagg aggctgagat
    22081 gttagaaatt gtttcagaag agctacgtca ctatcaagaa caaaaattga ttgagtaccg
    22141 taacaaaaat cagttagccc caaaaggagg cattgtattt gcaggtgatt ctctcattga
    22201 attttttcct ttaaaaaaag cttttggttc atgtttgcct attattaatc gaggtattgc
    22261 tgggatagat agtcagtggt tattgcgcca tttttctgtc caaattactg atttagagcc
    22321 taaacatatt tttttattaa ttggttgtaa tgatatcggg cttggatatg ataaatgtca
    22381 tattgtcaag actattgtag agcttattag ccagattcgt agtcattgtg tctatagtca
    22441 gatttatctc ttatctttat taccagtttc caacaatccc cgatatcaga agactgtcaa
    22501 aataagaaca aatgctatga ttgatgctat taataaagat ttagcaatga ttccaactgt
    22561 agaatttatt aatcttaata cttgtcttaa agacgaaaaa ggtggtttat cagatgagaa
    22621 tactctagat ggtttacatc ttaattttcc agcttatgct aaactagctg aaattattaa
    22681 atcttatatc tagcaaataa atgtactaat agcgatgagg caagaagtca gatagcagat
    22741 ggttcatcaa tcaattaaga aaaaagttat caagatacca ttaaaaatag ttgctcaaag
    22801 ttctttcaaa tcaaaagatt atgatatcgc tatgttgagt tttagtgtat aatgataatt
    22861 aaaggagtta ccatgaaatt tgaaaaaaaa caagtcttct atttagtcct tacgtttatc
    22921 ttatgctatg ggatcctagc aaactggcga aatggaacgg ctatcgtcac gactatttac
    22981 aaaacaagcc ttcctttttt ttatggagca gcaggtgcct atattgttaa tattgtaatg
    23041 agcgcttacg aaaaggtata tgtttatatc tttaaagact ggtcacatgt cttaaaagta
    23101 aaacggggta tttgtttact gttagcgtat ttgacatttt ttattttaat tacttggatt
    23161 atttccattg tcattccaga cttaattaca agtattagta ctctaacaaa atttgatact
    23221 ataacgatac aagaagttgt taacaatctt gagcacaata aactgttagc acgtactatt
    23281 cagtatattg gtggcgatgg caaacttaca gagacgattg ctaactatag tcaacagtta
    23341 ttaaagcaat ttcttactgt tttgacaaat attttaacat ctgtcacggt tattgcttct
    23401 gcaattatta atctttttat tagttttgtt ttttcgttat acgttttagc aagtaaagaa
    23461 gatctttgtc gtcagggaaa tactttagta gatacttata ctggtaagta cgctaaacgc
    23521 attcattact tgttagagtt gttgcatcag cgttttcacg gattttttgt tagtcagacc
    23581 ttagaagcta tgattttagg ttcgctgact gctagtggca tgtttatatt aagattacca
    23641 tttgcaggga ctattggcgt tttagtagct tttacagcat tgattccagt tataggtgct
    23701 tcaattggag cagctattgg atttatttta attatgactc agtccatgtc acaggccatt
    23761 atttttatca tttttttaat tattttgcag cagattgaag gcaattttat ttatccgaaa
    23821 gtagttggtg gatcgattgg attaccggct atgtgggtat taatggcaat tacaataggc
    23881 gcttctttaa agggaatagt tggtatgatt attgcagttc ctttagcagc gacactttat
    23941 caagtgatta aagataatat tcaaaaaaga caagctattc aaaaaaaaca agtttcctaa
    24001 aaggaacttg tttttttgtc gaataaaaag atggaggtaa tatgataaat gtattctata
    24061 aaatgtgatg ataataaagc catgccaaga gaacgtttga tgcgactagg agcagagtct
    24121 ctaagtaatc aagaattatt agcaatttta ttacgaacag gtaataaaga aaagcatgtc
    24181 ttagagctgt catcctatct tttatcgcat ttagacagtc tggcagattt taaaaagatg
    24241 tctttgcaag aattacaaca tttggcaggt ataggaaaag ttaaagcgat tgaaattaaa
    24301 gctatgattg agttggtttc ccgaatttta gcgacagata agacattaac tgatagcgta
    24361 ttaaccagtg ttcaggtcgc tgaaaaaatg atggcagctt taggagataa aaaacaagag
    24421 catttagtcg tattgtattt agataatcaa aatcgtatta ttgaagaaaa aactattttt
    24481 attgggactg tccgacgttc acttgcagaa ccaagagaaa ttttatacta tgcctgtaaa
    24541 aatatggcga ctagtctcat tgttattcat aatcatcctt caggaaatat tgaacctagt
    24601 tctaacgatt attgctttac tgaaaaaata aaacgatcat gtgaagattt aggcattatc
    24661 tgtctagatc acattatcgt tagctataaa gattattata gttttcgaga aaaatcaacc
    24721 cttttttaag tcagaagtca ttgacgaata agcggaacaa ttgtaaatct tcatctcgaa
    24781 caccttggag aagttcagga tgccactgaa cacctaaaaa aggaatggca tcgttggttg
    24841 atatgactgc ttcgatggta ccatcacgtg gatccctagc gattactttt aaatccttag
    24901 caacagtttt taaactttgg cgatgaaaag aattaattaa tgtcttatga ccataaatag
    24961 gatataagat agagtctggc tcaataatca tttcgtgtga taagaaatca gaaggcgctt
    25021 cttgccaatg tgagtcaatg tgttggttaa gatttcctcc taaggcaaca ttcattaact
    25081 gtgtaccacg acaaatccct aagattggtt tttttaatgt tatagcctcc ttgatgatag
    25141 ctagctcaaa tgtgtctcgc tctggtgaaa aatcatcatc aaaagcagcc ttctcttctt
    25201 gataatattt tgggtcaacg ttttgcccac caattaaaat gattttatca accatagata
    25261 cataagtttt agcggcggct tcatcaccaa tgggtaaaag aagcggcagc cccccagatt
    25321 gagtgactgc ctgtacaaat ccagtaggtg catatgacca tgggagatta tccaaagcca
    25381 tatttagtct ttgatttgca gttattccaa taatcggttt ggtcattata cctccttaat
    25441 ctagatgatt ttgattcata aaatagagta gtgtctggag ctcactggtc aaatcgacag
    25501 attgaacaat aactccttta ggaacttgta ggtgaacagg agcaaaactc aagattcctt
    25561 tgattcctgc ttcaataagt tgatcagtaa cttcttgagc atgaatgctg ggaaccgtta
    25621 agatagccgt ttcaatgtca gtgttcgcaa tccgttcttt gacagatgag ataccatgga
    25681 ctggaatatt atcagctgtt ttagtaccaa caagagcgtt atcatcggta tcaaaaccca
    25741 tggcaatttg catcttatta cgatcatgga agcggtaatg taatagagca cgccctatat
    25801 taccgcatcc aactaagata acgtttgttg tagagtgatc attaagcaag tcagcaaaaa
    25861 aattcatcaa tttggtaaca tcatagccaa acccacgacg ccccaattct ccaaaataag
    25921 aaaagtcacg gcgtacagta gcagagtcaa ttcccattgc atctgcaatt tgtttagaac
    25981 tggctttttc aacttggtca gcatggaatc gtttaaaaat acggtaataa agtgataagc
    26041 gctttgcagt cgcttttgga atagatttgt caataaccac tattttactc cttgtagatt
    26101 tctcgttaaa tatgtctgtc tttattgtaa caaaaagatt gtgaaaaatg caacattttg
    26161 attgtttttg tatgagttaa aaaagctaaa att
//
LOCUS       DAUGQX010000027        25230 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUGQX010000027 DAUGQX010000000
VERSION     DAUGQX010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25230
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.027"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            79..444
                     /locus_tag="VIA51_001084"
     CDS             79..444
                     /locus_tag="VIA51_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8683028.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            444..2108
                     /locus_tag="VIA51_001085"
     CDS             444..2108
                     /locus_tag="VIA51_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEQ8683029.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            2345..3235
                     /locus_tag="VIA51_001086"
     CDS             2345..3235
                     /locus_tag="VIA51_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEQ8683030.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHIRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            3465..4319
                     /locus_tag="VIA51_001087"
     CDS             3465..4319
                     /locus_tag="VIA51_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEQ8683031.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNLKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            4512..5708
                     /locus_tag="VIA51_001088"
     CDS             4512..5708
                     /locus_tag="VIA51_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEQ8683032.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            5971..6522
                     /locus_tag="VIA51_001089"
     CDS             5971..6522
                     /locus_tag="VIA51_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8683033.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            6589..6960
                     /locus_tag="VIA51_001090"
     CDS             6589..6960
                     /locus_tag="VIA51_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8683034.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            6998..8344
                     /gene="glnA"
                     /locus_tag="VIA51_001091"
     CDS             6998..8344
                     /gene="glnA"
                     /locus_tag="VIA51_001091"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEQ8683035.1"
                     /translation="MAITVADIRREVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDEADKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(8571..10253)
                     /locus_tag="VIA51_001092"
     CDS             complement(8571..10253)
                     /locus_tag="VIA51_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8683036.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(10255..10485)
                     /locus_tag="VIA51_001093"
     CDS             complement(10255..10485)
                     /locus_tag="VIA51_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEQ8683037.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            10770..11468
                     /gene="tsaB"
                     /locus_tag="VIA51_001094"
     CDS             10770..11468
                     /gene="tsaB"
                     /locus_tag="VIA51_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEQ8683038.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHASLEVIIEQLVEEGQMIFVGE
                     TAPFAEKIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            11440..11895
                     /gene="rimI"
                     /locus_tag="VIA51_001095"
     CDS             11440..11895
                     /gene="rimI"
                     /locus_tag="VIA51_001095"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEQ8683039.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQELGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            11885..12913
                     /gene="tsaD"
                     /locus_tag="VIA51_001096"
     CDS             11885..12913
                     /gene="tsaD"
                     /locus_tag="VIA51_001096"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEQ8683040.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(13084..13353)
                     /gene="rpsN"
                     /locus_tag="VIA51_001097"
     CDS             complement(13084..13353)
                     /gene="rpsN"
                     /locus_tag="VIA51_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEQ8683041.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(13589..14332)
                     /locus_tag="VIA51_001098"
     CDS             complement(13589..14332)
                     /locus_tag="VIA51_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8683042.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSC"
     gene            14572..15351
                     /gene="udp"
                     /locus_tag="VIA51_001099"
     CDS             14572..15351
                     /gene="udp"
                     /locus_tag="VIA51_001099"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEQ8683043.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            15372..16574
                     /locus_tag="VIA51_001100"
     CDS             15372..16574
                     /locus_tag="VIA51_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEQ8683044.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            16604..17275
                     /gene="deoC"
                     /locus_tag="VIA51_001101"
     CDS             16604..17275
                     /gene="deoC"
                     /locus_tag="VIA51_001101"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEQ8683045.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(17370..18539)
                     /locus_tag="VIA51_001102"
     CDS             complement(17370..18539)
                     /locus_tag="VIA51_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8683046.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDVLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSADQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            18745..19275
                     /locus_tag="VIA51_001103"
     CDS             18745..19275
                     /locus_tag="VIA51_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEQ8683047.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFFTRLFAK"
     gene            19324..19911
                     /locus_tag="VIA51_001104"
     CDS             19324..19911
                     /locus_tag="VIA51_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEQ8683048.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHIIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAEPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAV
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            20060..20797
                     /locus_tag="VIA51_001105"
     CDS             20060..20797
                     /locus_tag="VIA51_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8683049.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
                     SSYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPR
                     TRKLTCSHCHQKSYCLELAKEDTVSRR"
     gene            complement(20854..21153)
                     /locus_tag="VIA51_001106"
     CDS             complement(20854..21153)
                     /locus_tag="VIA51_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEQ8683050.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDETTKKTLGAFAGKLPF"
     gene            complement(21346..21720)
                     /locus_tag="VIA51_001107"
     CDS             complement(21346..21720)
                     /locus_tag="VIA51_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683051.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLENKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            21890..22111
                     /locus_tag="VIA51_001108"
     CDS             21890..22111
                     /locus_tag="VIA51_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683052.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(22191..24473)
                     /locus_tag="VIA51_001109"
     CDS             complement(22191..24473)
                     /locus_tag="VIA51_001109"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEQ8683053.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPPSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(24495..25154)
                     /locus_tag="VIA51_001110"
     CDS             complement(24495..25154)
                     /locus_tag="VIA51_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8683054.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
BASE COUNT         7862 a         4300 c         5236 g         7832 t
ORIGIN      
        1 gttagctatt ctatctcttt tacattactt ctaaaatatg ataaaatagg atgataaaaa
       61 ctttttgagg tagtaactat gactgtaaaa attaatacaa aagatggtct aatcgagcta
      121 tccgacgatg tgattgcaac tgtcgtggga ggatcagcaa cggaaatttt tggtgttgtt
      181 ggaatggcca gcaaaagtgc aataaaagac aattttcaat cactacttcg caaagaaaac
      241 tacgctaagg gtgttgtggt aaaatcaaca gatctgggta tttctgttga tgtctacact
      301 gtgatgagtt atggtgtgaa aatcagtgaa gtctctaaaa atatccaaga acgcgtgaaa
      361 tttaaccttg aaagtcagct tggtctcact gctgatatgg ttaatgttta cgtgcaaaat
      421 attaaggttg taggagaaaa ttagtgtcaa atattacaac aagcttattc caagaaatgg
      481 tccaagcggc agcgactcgc cttggcaaac aagcagaata tgttaattcc ttaaatgttt
      541 ttcctgttcc agatggtgat acaggaacaa acatgagcat gactatggac aatggtgcca
      601 aggaagttgc tgataaacct gcgtcaactg tgggagaagt tggacaaatg ttatcaaaag
      661 gtcttttgat gggagcgcgt ggaaattctg gagttattac ttcacaactt tttcgtggtt
      721 ttggtcaaag cattaaggga aaagatgagc tgacaggtaa agatttggca caagcctttc
      781 aagtgggtgt agaagttgcc tacaaagcag tgatgaaacc tgttgaagga acaattttaa
      841 ctgtttctcg gggtgcagcg actgctgcct taaaaaaagc agatcttaca gacgacgccg
      901 tggaagtcat gcaagctgct ttagacggtg ccaaaggtgc ccttgctaag acacctgatt
      961 tattaccagt ccttaaagaa gttggtgtgg ttgattcagg cggtcaaggt cttgtcttta
     1021 tctatgaagg tttcctatct gctttgaatg gcgactatgt gacttcagca gactttaaag
     1081 cgactcctgc taacatgtct gaaatgatta atgctgagca tcacaaatcc gttgttggtc
     1141 atgtggctac tgaagacatt acctacggtt attgtactga aatcatggtt gcccttaaac
     1201 aaggcccaac ctatgtgaaa gaattcaact atgatgagtt tcaaggctac cttagtggcc
     1261 ttggtgactc gctgttagtg gtcaatgatg atgagattgt taaagttcac gtccatactg
     1321 aagaccccgg acttgtgatg caagaaggtc ttaaatatgg ttcgctcatc aagattaaag
     1381 tggacaatat gcgtaaccag catgaagcac aggttcaaaa gactgatgtc gaaaaaaaca
     1441 aggctgaagt aaaagacttt ggcttgattg cagtagtagc tggagaaggt ttatctgaaa
     1501 ttttcaaggc gcaaggtgtt gattacgtga tttctggtgg tcaaaccatg aatccatcta
     1561 cagaagatat tgttaaagct attgaagcag ttaatgccaa acaagtcatt atcttgccaa
     1621 acaataaaaa tatctttatg gctgcccaat ctgctgcaga agtggtggat attccggctg
     1681 ctgttgttgc aacacgtact gttccgcaag gatttaccag cttgttggcc tttgatcctt
     1741 caaaatcttt agaggacaat gtagcagata tgtcaactag tctttctgac gtggtcagtg
     1801 gaagcgttac tttggcagtc cgtgacacca ccattgatgg tttagaaatc catgaaaatg
     1861 atttcttggg aatggttgat ggtaaaatca tcgtttcaaa cccagacatg gaagcaactc
     1921 taaaagctgc ctttgaaaag atgattgacg aagatagcga gattgtgact atctttgttg
     1981 gtgaagaagg tgatcaagac ttagcagaag aacttgctgg gtatttagga gagacttacg
     2041 aagatgtgga agttgagatc catcaaggag atcagcctgt ttacccatat ctcatgagtg
     2101 tagaataata gaatataata aaaaaagagg agttaggcaa aggtctgact ctttttgtct
     2161 atattgatgt cgtaatgagt ggttttagtg atggtaagcc cctaaaaaat gagggtaatc
     2221 catcacaaag ctaatggtta cgatttaatt tgacaaaacc tagaaaaaca ttataattgt
     2281 attataacaa taagtcaaga actgaaaacg gttcagttct aagatatgac aaggaggaga
     2341 ttttatgtta ggaccattta tctttattgc ttttggggtt attgtaatcc tagctattgt
     2401 tgccagtacc ctttatgttg ttcgtcaaca atctgttgcc atcgtggaac gttttggtag
     2461 ataccaaaaa acagccacga gtggtattca tatccgactt ccgtttggga ttgacaaaat
     2521 tgctgcgcgt gtgcagctgc gtcttttaca gtcagaaatc atcgttgaaa ccaaaaccaa
     2581 ggacaatgtg tttgtaactt tgaatgttgc cactcagtat cgtgttaacg aacaaaatgt
     2641 aacagatgct tactacaaat taatgaaacc tgaatctcaa atcaagtctt atattgaaga
     2701 tgccttgcgg tcatccgtgc cgaagttgac cttagacgaa ttgtttgaga aaaaagatga
     2761 aattgccttg gaagtacaac atcaagtggc agaagaaatg tcaacctatg gatatattat
     2821 tgtcaaaacc ttgattacca aggtggagcc tgatgctgaa gtcaaacagt caatgaatga
     2881 aatcaatgcg gctcaacgca aacgtgtagc tgctcaagag ttggcaaacg cagataaaat
     2941 taaaattgtg acagcagcag aagcagaggc tgaaaaagat cgattgcacg gggtagggat
     3001 tgcccaacag cgtaaggcca ttgtggatgg tttggcggag tctattcaag agcttaaaga
     3061 agcgaatatt tccttaaacg aagaacaaat catgtccatt ttgttgacca accaatacct
     3121 ggataccctc aatacctttg cggcaaaagg aaaccaaacc ctttttctac caaatacacc
     3181 aagtggggta gaggatatcc gtacacaagt tttatctgcc cttaaaacaa aataacgtgt
     3241 aaaagcttgg ctaaaaagtt gctcaatact ggatttagca gaaggctatc ataccttgtg
     3301 aagtggcaaa cgacgaaatg aatacattac ttttattgga gaaatgaaag taaaaaaagc
     3361 ctttttcatg attaacaaca tagtattgat taaatgttaa gttgtattga cttttaaatt
     3421 aaataagttt aaaatcaact taataagcaa aaaggagatt ttcaatgaaa tccaaaaaag
     3481 ttgttagtgt tatatcactt accttatccc tttttttggt gacaggttgt gctaaagttg
     3541 ataacaacaa atcagttaat cttaagcctg ctactaaaca aacctataat agctatagtg
     3601 atgaccaatt aagatcgcgt gaaaatacca tgtctgtttt atggtaccag cgagctgcgg
     3661 aaactcaagc gctttattta caggggtatc agttagcaac ggatcgctta aaagaacaac
     3721 tcaataaacc aacggataaa ccttattcaa ttgtattaga tattgacgaa acagttcttg
     3781 ataatagccc ttatcaagct aaaaatgttt tggaaggaac aggatttaca cctgaaagct
     3841 gggattattg ggtacaaaag aaagaagcaa aaccggttgc tggtgctaaa gactttttgc
     3901 aatttgcaga ccaaaatggt gttcaaattt actacatttc agacagatca actactcaag
     3961 tagatgctac aatggaaaat ctccaaaaag aaggtattcc agtacaaggt cgtgatcatc
     4021 ttctattctt agaaaaaggc gtaaaatcaa aggagagtcg tcgtcaaaag gtcaaagaaa
     4081 caactaatgt aacgatgcta tttggtgata atcttctaga ttttgctgat ttttcaaaaa
     4141 aatctcaaga agatagaaca gctttattat cagatttaca agaagagttt ggaagacgct
     4201 ttatcatttt ccctaatcct atgtatggtt catgggaagg tgccatttat aaaggtgaaa
     4261 agctggatgt gcttaagcaa ctagaggaac gccgtaaaag tttaaaaagc tttaaataaa
     4321 gtaattgaaa aagaggtgca aaagaaaatg taacctcttt ttaagtacta ttattttctg
     4381 aaaatagggt taatgactga aaaaaatgtt gattttgtga aatgattatt ttattatttt
     4441 catattttat ctttatgcta ggaattgtgg tataatggag gagtataaaa aatattaagg
     4501 agtctattca catggctaaa ttgactgtta aagacgttga tttgaaaggt aaaaaagtcc
     4561 tcgttcgtgt tgactttaat gtgcctttga aagacggcgt tatcactaac gacaaccgta
     4621 tcactgcggc tcttccaaca atcaagtata tcatcgaaca aggtggtcgt gctatcctct
     4681 tctctcacct tggacgtgtt aaagaagaag ctgacaaaga aggaaaatca cttgcaccgg
     4741 tagctgctga tttagctgct aaacttggtc aagatgttgt attcccaggt gttactcgtg
     4801 gttcaaaatt agaagaagca atcaatgctt tggaagatgg acaagttctt ttggttgaaa
     4861 acactcgttt tgaagatgtt gacggtaaga aagaatctaa gaatgacgaa gaacttggta
     4921 aatactgggc ttcacttgga gatggaatct tcgttaacga tgcatttggt acagcacacc
     4981 gtgctcacgc atcaaacgta ggtatttcag caaacgttga aaaagctgta gctggtttcc
     5041 ttcttgaaaa cgaaattgct tacatccaag aagcagttga aactccagaa cgtccattcg
     5101 tagctattct tggtggatca aaagtttctg ataagattgg tgttatcgaa aatcttcttg
     5161 aaaaagctga taaagttctt atcggtggtg gtatgactta cacattctac aaagctcaag
     5221 gtatcgaaat cggtaactca cttgtagaag aagacaaatt ggatgttgct aaagacctcc
     5281 ttgaaaaatc aaatggtaaa ttgatcttgc cagttgactc gaaagaagca aacgcatttg
     5341 ctggttacac tgaagttcgc gacactgaag gtgaagcagt ttcagaaggc ttccttggtc
     5401 ttgacatcgg tcctaaatca atcgctgagt ttgaccaagc acttactggt gctaaaacag
     5461 ttgtttggaa tggtccaatg ggtgtctttg aaaaccctga cttccaagct ggtacaatcg
     5521 gtgtcatgga cgctatcgtt aaacaaccag gcgttaaatc catcatcggt ggtggtgatt
     5581 cagcagctgc tgctatcaac cttggccgtg ctgacaaatt ctcatggatc agtactggcg
     5641 gaggcgctag catggaactt ctcgagggta aagtattacc aggtttggca gcattgactg
     5701 aaaaataata gtcattataa tatatagtaa agggcatgct gatgcatgtc tttttttagt
     5761 tgatcatgta gagttattga actttcccta acttcactta tcatttacta gtttttagat
     5821 atagtggtat ttggctgaca ctgcattttt caaaagttta tgacgatttc atatcaattg
     5881 gtttataaaa gatatcctaa tcataaataa aacgtttacc aaaagggttt tatggattga
     5941 tatgttaaaa tagatagtga agggataggt atgaaaacgt taagaaaatt attatctaat
     6001 tacaagtttg atattaaaaa gtttaaattg ggaatgagaa cattgaaaac aggcttatcg
     6061 gtctttttag ttttattggt ttttcattta tttggttgga aagggctcca aattggtgct
     6121 ctaactgctg tatttagttt aagagaagac tttgataaaa gcgtgcactt tggcttttct
     6181 agaattattg gtaatagtat aggtggccta ctctccttag tattttttgc attcaatgag
     6241 atatttcatc aagctttttg ggttacttta ttaattgttc ctatttgtac catgttatgt
     6301 atcatggtta atgttgcatg taataataaa tcaggtatta ttggggcagt ggctgctctt
     6361 ttgattatta cactgtctat tccaacagga caaacgttta tttatgtgac ttcgcgggta
     6421 tttgaaacat tttgtggcgt ctttgtagct attttagtta atactgatgt tgaacttatt
     6481 aaaaataaat ggtttaacaa aaaacacagt gatgttagat aatataacat atatacttga
     6541 caggttattt ttttcagcct ataataagga agatgaaagg agtttgtcat gaaagaaaaa
     6601 gaacttagac gctcaatggc tgtttttcct attggaacgg tgatgacatt aacagatctc
     6661 tctgcgagac aaattcgcta ttatgaagat caaggtttaa ttaagcctga acgaacgcaa
     6721 gggaatcggc gtatgttttc cttaaatgac atggaccgac ttttggaaat taaagatttt
     6781 ttgtctgagg gattaaatat tgcagctatt aaacgcgaat atgtcgagcg tcaaggtaag
     6841 ttaatgcaaa aacaaaaagc tctaacagat gcagatgtca gacggatctt acatgatgaa
     6901 atgctgacac aaagcggttt ttctactccc tcacagcata ttggtaattt tcgtatttaa
     6961 gatatgaatt gtataaaatt taaaggagac ctatttaatg gcaataacag tagctgacat
     7021 tcgtcgtgaa gtcaaagaaa aaaatgtaac gtttcttcgc ttgatgttca ctgatatcat
     7081 gggcgttatg aaaaatgtgg agattcctgc aactaaagaa cagttagaca aagtattgtc
     7141 taacaaggtt atgtttgatg gttcatctat cgaaggtttt gtacggatca atgagtcaga
     7201 tatgtacctt taccccgatt tagacacttg gattgttttt ccctggggag atgaaaatgg
     7261 agcagttgca ggtttaattt gtgatattta tacagcagaa ggaaagcctt ttgcaggaga
     7321 tcctagagga aatttaaaaa gagccctgaa acacatgaac gagatcggct acaaatcatt
     7381 taatcttgga ccagaaccag aatttttcct ttttaagatg gatgataaag gtaatccgac
     7441 acttgaagtt aacgataatg gtggttattt tgatttagcg ccaattgact tagcagacaa
     7501 cacgcgccgt gaaattgtga atattttaac gaaaatgggt tttgaagtgg aagctagtca
     7561 tcatgaagtg gctgttggtc aacatgagat tgattttaaa tatgcagatg ttttgaaagc
     7621 ttgtgataat attcaaattt ttaagctagt tgtaaaaacg attgcccgtg aacatggact
     7681 ttatgctact ttcatggcta aaccaaaatt tggaatagct ggatcaggga tgcactgtaa
     7741 catgtctttg tttgataacc aaggtaataa tgctttttat gatgaagctg ataagcgagg
     7801 gatgcagtta tcagaagatg cttattattt cttgggagga ctaatgaagc atgcttataa
     7861 ctacactgct atcactaacc ctacagtgaa ttcttataaa cgattagttc caggttatga
     7921 ggcacctgtt tatgtcgctt gggctggaag taatcgttca ccgcttatcc gtgttccagc
     7981 atcacgtggt atgggaacgc gtttggagtt acgttcggtt gatccgacag ctaatcctta
     8041 tttagccttg gctgttctct tggaagctgg attagatggt atcattaaca aaattgaagc
     8101 tccagaaccc gttgaagcta acatttatac catgacaatg gaagaacgaa atgaagcagg
     8161 cattattgat ttgccatcaa cgcttcataa tgccttaaaa gctcttcaaa aagatgatgt
     8221 ggtacaaaag gcactaggtt accatatcta cactaatttc ttagaagcaa aacgaattga
     8281 atggtcttcc tatgcaactt ttgtttctca atgggaaatt gaccattata ttcataatta
     8341 ttagacttat caggacctgc tcaagttgag tgggtctttt ggatgagcta ttgtatttga
     8401 gctagcaagc tattattagc tgatcggaca ccaattgatt ttccattata gaaaactaaa
     8461 aaccagtcca tgttctatga ggactggttt tagtttgata attatctgaa ctagaactga
     8521 tatgttaaag atatagacag atagtattaa gaaatgagtc ttatttgatt ttagtgctta
     8581 tcaggtgtta agaccatcgg aatgataatt ggttcacgct cagtcttttc atacaagaat
     8641 ggacgaagag cattgacgat agcaccgtta actgattgga tgctagcatc cttatttttt
     8701 aaagcaatac ggatagcgtt aaagagcaca cgttggcttt cgcggatcaa gtcacctgac
     8761 tcacgcatat aaatgaaacc acggctcaga atatctggtc cagctaaaat catttgtgtg
     8821 ttaaaatcaa cagttgcaac agctaagaca acaccatctt ctgacaaatc acggcggtcc
     8881 cgtaaaacgg ctgctccaat atccccgatg ccattaccat ccacgtagat gtcttgggca
     8941 ttaaagtgac cagcaatacg cgcactgtca ctggttaaag ctagaacgtc tccattttcc
     9001 ataataaaga tattttcttt tggaatacca atatccatcg ccagtcctgc atgaactttt
     9061 tgcatgcgat actcaccatg tactggcatg aaatattttg gtttaatcaa actaagcatg
     9121 agcttttgtt cttgctgtcc tccatgacca gaagtatgaa tattattgac ttttccatga
     9181 ataacatcaa caccagcttc ttggatggta ttgattaatt tattgacact tgtggtatta
     9241 ccagggattg gacttgatga gaaaatcaca gtatcaccag gctgtaaagt tacttgacga
     9301 tgagtgccat tagcgatacg agcaagtgct gccatagact caccttgact acctgtacac
     9361 ataattaaaa cttcactagc atgaagattt ttaagttcgc ttggctcaat gaaggtacct
     9421 tttggaactt taatatagcc aagttcaata ccgttaacaa ttgctttttc catagaacga
     9481 ccaaaaacgg caattttacg tcccgtttta acagcagctt ctgcagcctg ttgcaaacgg
     9541 tagatgtttg aagcgaagga agcaaaaata atacgaccat gaataccttc gataattttt
     9601 aaaatggatt ggccaacaac tttttcagag ttagtaaagg ttgggatttc agcattagtt
     9661 gagtctgata ataagcaaag gacaccttct tcaccaagcg ctgccatacg ttgtaaatct
     9721 gcaggatctc ctactggcgt gaagtcaaat ttaaaatcac cagtacagat aatcttacct
     9781 tgaggggtgt ggataacaat accgaccggt tctggaatgg aatgagtagt cttgaagaaa
     9841 gtgacgctca tgtttttaaa agttaactcg gtgttgtgat tgatttcgta aacagttgct
     9901 tcacgccaaa gaccatgttc ttccaattta ccacggataa gagcaagtgc taaaggtcct
     9961 gcgtagatag ggatattagc ctgtttgaga agaaatggaa taccaccaat gtggtcttcg
    10021 tgaccatgtg taataacaag agctttgacc cggtctaagt tatcgacaat gtaagaatag
    10081 tctggaataa cgtaatcaat tcccaaaaga tcatcttctg ggaatttgat accggcatca
    10141 acgataatga tttcgtcttg atactcaata ccataagtat tcttcccaat ctctcccaga
    10201 ccaccaatgg caaacacccc aacttcatta ggttttaaac tgatatttgt catcttagaa
    10261 ctccgttaat tcaaaaacac cggtctcttt ttcgtaatcg aggtgtttgt cagaaagtag
    10321 ctcgataaat tccacgttat aataggtgtt atcttcaacg agacgacgag ccttgatacg
    10381 gccatcgagt tcatcagtag catcaatatt aagatagagt gctttagtac tttcacgacg
    10441 tgggctttga tcctttgttt cttgatagaa aactttataa atcatttgtt tttaaattcc
    10501 tttcgttatg aatcaattat ccaaacaata ataaataggt caaaaggtag gtgttccatt
    10561 ttgacggttt tatatgttgt cattattgtg tagtagatta attcctgatt ctgtgcaatt
    10621 attacaatta taccataaac ttagctttta gtaaaaaatt taggtacatt tatggtatag
    10681 tctaaatcaa attaagagtc agcctttttg tttatgattc ttaatttgtg ttataattga
    10741 tactagaact tgcagtagaa aggcataaaa tgaagacact tgcatttgat acctcaaata
    10801 aaaccttgtc ccttgctata cttgatgatg agacacttct agcagatatg acccttaaca
    10861 ttcagaaaaa tcatagtgtt agccttatgc ctgctattga ttttttgatg acttgtactg
    10921 atcttaaacc tcaagattta gaaagaatag tggttgcaaa aggccctgga tcttacacag
    10981 gtttacgagt ggcagttgct actgcaaaaa cgttagcgta cagtttaaat attgcattgg
    11041 tcgggatttc gagtctatat gctttggctg cgtctacttg taaacagtat ccaaatactt
    11101 tggtggtgcc attgattgat gctagaaggc aaaatgcgta tgtaggttat tatcggcaag
    11161 gaaaatcagt gatgccacaa gcccatgctt cactagaagt tattatagaa caattagtag
    11221 aagaaggaca gatgattttt gttggggaga ctgctccttt tgctgagaaa attcaaaaga
    11281 aactacctca ggcgatacta cttccaaccc ttccttctgc ttacgaatgt ggtcttttgg
    11341 ggcaaagttt ggcaccagaa aatgtagacg cctttgtccc tcaatatctc aagagagtgg
    11401 aagctgaaga aaactggctc aaagataatg agataaaaga tgatagtcac tacgttaagc
    11461 gaatctaata tgaaaacagt tgaagaacaa gcaaaaaata tttatcagct tttggaaatg
    11521 gtttatggca cgtctccttg gactttagaa caagtattaa tcgatatacg gcgggatcaa
    11581 acagattatt tcctactata tgatcatgat aaattgctag gttttttagc tattcaagat
    11641 ttagctggtg aagttgaaat gactcaaatt gctatactac ctagtcatca agaacttggg
    11701 ctagcgtctc aattgatgac gcatttagat agcattgaaa gtgacatctt tttagaggtt
    11761 agagaatcta atcatagagc acagggttta tatcagaagt ttggttttaa atttattggc
    11821 aaaagaccag actactatag aaatcctata gaaacagctt tattgatgaa acgggaagga
    11881 aaacatgaca gataggtata ttttagcagt tgagagttct tgtgatgaga ccagtgtagc
    11941 gattttaaaa aacgaaagta ccctcttaag taatgtcatt gcaagtcagg ttgagagcca
    12001 caaacgcttt ggtggtgtgg tgccagaagt agctagtaga caccatgtcg aagtgattac
    12061 gacttgcttt gaggatgctt tgcaagaagc tggcatcagt gcttcagatt tatcagcagt
    12121 tgcggtaact tatggccctg gacttgttgg agccttgtta gttggattag cagctgcgaa
    12181 ggcttttgct tgggcaaatc atttaccttt gattccggtt aatcatatgg caggtcactt
    12241 aatggcagcg cgtgaacaaa agcctttagt ttatccttta atagcactgt tggtttcagg
    12301 aggacacaca gaattggttt atgtcccaga gccaggggat tatcatatta ttggcgagac
    12361 gcgtgacgac gctgttggtg aggcttatga taaagttggg cgtgtgatgg gcttaaccta
    12421 tccggcagga cgtgaaattg accagttggc tcataaaggt caagatactt atcatttccc
    12481 tcgtgctatg ataacagaag accacttaga attttccttt tcaggactca agtccgcttt
    12541 tatcaatctt catcataatg ctaagcaaaa aggcgatgaa ctgattctag aagatttgtg
    12601 tgcatctttt caagcagctg ttctagatat tttattggcc aaaacaaaaa aagctctgag
    12661 cagataccct gcaaagatgc ttgtagtggc tggtggtgta gcggcaaatc aaggattacg
    12721 agatagatta gcacaagaaa ttacacatat agaagttgtg attcctaaac taagactctg
    12781 tggagataac gcgggtatga ttgctttagc agcagctatt gagtatgaca aacagcattt
    12841 tgctaatatg agcctaaacg cgaagcctag tttagctttt gaccagtttc cagacagttt
    12901 tgtaataaac tagtcacact tgctagttag taagatttat aatggataag aatctccctt
    12961 tgaaaaaaca acccggtatc ttggcatacc gggttgtcat gatgataagt aattggcttc
    13021 tatggttact aataattcag ataattacct gcaaaataat tgtctgccta aggtgaagta
    13081 agcttaccag ctagctttag tgacgccagg aagctgtcct ttgtgagcta agtcacggaa
    13141 attgatacgg ctaacaccaa acttacgcat gtaagcatga ggacggccgt caattttgtc
    13201 gcggttcttc aagcggtttg gatttgaatc acgaggcaat ttgcgcagtg attcataatc
    13261 gcccttcgct tttaagtcac gacgaaggtc agcgtactgt tcaatcagtt ggagctgctt
    13321 ttggtattta gcaatttttg acttttttgc cattgctttc tccttcttaa tatttaataa
    13381 cctcagagtc gttatcagcg ctctgaatcc acttaactgg tatttaactg gttaagtgga
    13441 tatataatca ttatacaata aataaaagca aaagcaaata aaaaaaatta actagttatc
    13501 ttttttagcc ataatatcaa aaaactccac atctaagtgt gggagtcagg tattaataac
    13561 tgtttaaagg tgtttaatga gtgtcgcttt agcaactttg agattgaact tttaagtcaa
    13621 ataaatcagc aggaacgtag tgtttggttg agaccaagat gtctttacca ttgtagagag
    13681 tttcttggat taaaataaaa gcactatttt ctgatagagt atacttagtt gctgtgtaat
    13741 tgccagtctt ggtatagccg atttggttgc aggaatgaga agctttacca gattcataga
    13801 ttttctcttc taagaaagta agaaggggct cttcttgatt gagatttata gcatatttag
    13861 aaataacctc aatagggata aaagataaac tataagcaat agctttattt tggctatgat
    13921 accagcgatc aacaataatc acaacaggag tttcttgttt tagggatgct gtaatggcaa
    13981 cagtgggcac ttcaatccga tattccaact caacctttgt gatgtcagat gataggcttg
    14041 catatatggg gtgttgaaga tattcgaaac cttggtgata tttagtttca ggagtcttga
    14101 gtataaaatt tccctttcct ctgatatttt ttatgagatg atcctcttgg aggagggcta
    14161 gggatttacg tagtgtcatc cgactgacat tgagctgtct agcaagttca ggttctgatg
    14221 gcagttgcat gccaggacta tatgtaccat cttgaataag ttgaaaaata gtattatata
    14281 cttgcacatg tttaagtttt ttgagttttt tggttaagtc gttagtagac atatcactta
    14341 cctcattaat aatctttagt ggagtttaac ttgtctaaaa actattttag cactaacagt
    14401 attccttgat tagaattgta cccatctata gtgttagtat ctcacactca ggtacttttt
    14461 gtcaaaaaag agatgaaaaa caccttaaaa aagcgtttac aaaatagagt gtgtgtgata
    14521 ctatacaagt gtatcaaaaa ttagacaagt aaaatacagg aggtttttaa catgcaaaat
    14581 tattcaggtg aagtcggatt gcaatatcac ctacagattc gtccaggtga tgtaggtcgt
    14641 tatgttatca tgccaggtga tccaaaacgt tgtgcaaaaa ttgcagaaca ttttgataat
    14701 gcagttcttg tagcagacag ccgtgaatat gttacgtata caggtacatt aaacggtgaa
    14761 aaagttagtg ttacttcaac tggtattggt ggtccatcag cgtctattgc gatggaagaa
    14821 ttgaaacttt gtggcgctga tacctttatc cgtgttggaa catgtggtgg tattgacctt
    14881 gatgttaaag gcggagacat cgttattgca actggagcta tccgtatgga aggtaccagt
    14941 aaagaatatg ctccgattga atttcctgct gtagctgact tggaagtgac aaatgctcta
    15001 gttaatgcag ctaaaaagct tggttataca agtcacgcag gagtagttca atgtaaagat
    15061 gcattttacg ggcaacatga gccagaacgt atgccagtta gttatgaatt attaaataaa
    15121 tgggaagcat ggaaacgtct gggaacaaaa gcgtctgaaa tggaatctgc agctcttttt
    15181 gtagcagcaa gtcatctagg agttcgttgt ggatcagatt tccttgttgt tggtaatcaa
    15241 gaacgcaacg ctttgggtat ggataaccca atggctcatg atacagaagc agctattcaa
    15301 gttgctgttg aagcactccg cacacttatt gaaaatgata aatcacaata agcgaggttt
    15361 tggaagtcat catgcaattt atttatagta ttattggtat tttattggta ttaggaattg
    15421 tgtatgcaat ttctttcaat cgtaagagtg tttctctaag tttaattgga aaagctctta
    15481 tcgttcaatt cattattgcg ctaatcttag tacgtatccc actaggccaa caaattgtta
    15541 gtgttgtttc aactggagtt actagcgtaa tcaactgtgg tcaagctggt ttaaattttg
    15601 tgtttgggtc attagcagat agtggcgcaa aaactggttt tattttcgct attcaaacgc
    15661 ttggtaatat tgttttctta tctgccctag ttagtctact ttattatgta ggaatccttg
    15721 gatttgtagt aaaatggata ggtaagggcg ttggtaaaat tatgaaatcc tcagaggttg
    15781 agagttttgt tgctgtagct aatatgtttc ttggtcaaac agacagtcca atcttggtta
    15841 gcaaatacct aggtcgtatg actgatagtg agataatggt tgtgttggta tcaggtatgg
    15901 gaagtatgtc agtttctatt cttggtggct atattgcatt aggcattcca atggaatatc
    15961 tcttgattgc ttcaacaatg gttcctattg gcagtattct cattgctaaa atcttattgc
    16021 ctcaaacaga acctgttcaa aaaattgatg acattaagat ggataataaa ggtaataacg
    16081 ccaatgtgat tgatgcaatc gctgagggtg caagcacagg tgcacaaatg gctttctcaa
    16141 ttggtgctag tttgattgcc tttgttggtt tagtttcttt gattaatatg atgttaagtg
    16201 gattgggaat ccgcttagaa caaatctttt catatgtttt tgctccattt ggttttctta
    16261 tgggatttga ccacaaaaac attcttctag aaggaaacct tcttggaagt aagttgattt
    16321 taaatgagtt tgtttcgttc caacaattgg gtcacctaat caaatcttta gattatcgta
    16381 cagcattggt agcaactatt tcactctgtg gttttgctaa tttatcaagt ttaggtattt
    16441 gtgtttcagg tattgctgtt ctttgcccgg agaaacgtag caccctagct cgacttgttt
    16501 tccgtgcaat gattggtggt attgctgtaa gtatgcttag cgcctttatc gtcggtattg
    16561 taactctatt ctaaacgttg acaaaagaaa gaaggatagt aacgtggaag taaaagatat
    16621 tttaaaaacg gtagaccata ctttgctagc aacaacagca acgtggccag aaatccaaac
    16681 aattttagat gatgccatgg cttatgaaac agcttcagca tgtattccag cttcttacgt
    16741 caaaaaagca gcagaatacg tttcaggtaa attagctatt tgtactgtta ttgggttccc
    16801 aaatggctat agtacaactg cggcgaaggt ttttgaatgt caagatgcta ttcaaaatgg
    16861 tgctgatgaa attgacatgg tcattaattt gacagacgtt aaaaatgggg attttgatac
    16921 tgttgaagaa gaaattcgtc aaatcaaagc taaatgtcaa gaccatatct taaaagttat
    16981 cgttgagaca tgtcaattaa ctaaagaaga acttatcgaa ctttgtggag ttgtcacacg
    17041 ttcaggtgca gactttatta aaacctctac tggtttttcg acagcaggtg ctacatttga
    17101 agatgttgaa gtgatggcaa aatatgtcgg cgaaggtgtt aaaattaagg cagcaggtgg
    17161 aatctcatca ttggaagatg ctaaaacatt tattgcttta ggagcttcac gcttgggtac
    17221 tagccgtatc atcaagattg ttaagaacga agctacaaaa accgatagct attaacttaa
    17281 tcataccgat ttagcttgag actaaaacaa aaaactcata taataggagt taaaaagcct
    17341 actatcttag tgataatagg cttttttagc tatgaagact tccctgcgat ccatcctgaa
    17401 caaagagctg aggtaatatt aaaccctccg gtatgagcat taatatctaa gacctctcca
    17461 gcgaaataca ggccaggaac tttcttgctt tccaaggttt tagggttgat ttcttttaaa
    17521 tctacgcctc ctttggtcac aaatgattta gccaaagaca tttttcctgt aatgggtatc
    17581 tggaggtgtt tgagtttatc aagcaattcc ttttcttgtt ttggagagag ttgtttgacc
    17641 ttttcggggt aatcttctga taaaaaatca gctactcgtt caggcagtag gcctttaaga
    17701 gcatttttga tgtttttatc acgttgatca ctcagataag cggttaagtc atctgttgat
    17761 aagtgtggca aaaagtccag ctctgcaatt tctccacctt tcacaaaaga ggacagacga
    17821 agagctgcag gtcctgaaag gccaaagtgg gtgaagagta agtcgtgtgt gatgacgtgt
    17881 ttgtcataac taagagtaac gtcgtctagg gaaatacctt gcaagacttt gtgaggaaaa
    17941 tcagttaaca gagggctctc agcagcttct aaatcagtca cggtcagttt aaaatgccgt
    18001 gcaatatcat gtccaaaacc tgttgaaccc gttgaagggt aggacttgcc tcctgtggtc
    18061 acaatcaatt tttggcaggt gaaagtctgg tctgcagatt tgaggtagaa gaggtcatct
    18121 tgttttttaa cggaaaccac ttcagtgctg gttagcacct gacccccaag agccttgatt
    18181 tttttctcca gagcatcaat gattgtcctt gatttatctg ttgtggggaa catccgtcca
    18241 tggtcttctt ctttgagttt gacgccgttt tcctcgaaaa aggcaatgat gtcatggttg
    18301 tcaaactggg aaaaaacact atataaaaag cggccatttc caggaatgcc agccataagg
    18361 acatcaaggt taccactatt agtgacatta cagcgtccac caccggttcc cgctaatttt
    18421 ttgcctaagc ggcgattttt ttcaattaag agagttttat agccatagta gctgctggag
    18481 atggcggcca tcatgccagc agggccacct ccaataataa tcgtatcgta ttgagtcata
    18541 gccttatttt agcataaaag cgggggattt aatagtcagg taaatgaact aacatggcat
    18601 accgtttttt acgcatttaa acaatgcttt caagtaataa ttgatgcctt tggcacgact
    18661 gaaatgaggt caaattgaca gaatactcct attatggtac tatttttaat aagaatattc
    18721 agtgatagtg ataaagagga aaatatggga attgaaaaga cagttagtga actagctgat
    18781 attttgggag tgagtcgtca ggccgtcaat aatcgtgtta agtctttacc cgaagaagat
    18841 cttgacaaaa atgaaaaagg cgttactgtg gttaagcgca gtggtcttgt taagctggaa
    18901 gagatctata aaaaaacaat ttttgacgat gagcctatca gtgaagaaac gaaacaacgt
    18961 gagcttttag agattctcgt ggatgagaag aacactgaaa tcacgcgcct ttatgagcaa
    19021 ctcaaagcca aagatgctca acttgcctca aaagatgagc aaatgcgtgt taaagacgtg
    19081 cagatcgctg aaaaagataa acaattggat cagcagcaac aattaactgc taaagccatg
    19141 gctgataaag aaaccctaaa attagaattg gaagaagcta aagcagaagc caaccaagct
    19201 cgcttacaag tcgaagaagt tcaggctgaa gttggcccta aaaaaggctt tttcacccgc
    19261 ttgtttgcga aataatcaca aaaaatgacg aaggccctat cagggtcttt tttggaggaa
    19321 aacatgaaac acttagatac ttatattgcc tttgatttag aatttaacac tgtcaatgac
    19381 gttagtcata tcattcaagt atcagcagtc aaatatgacc accataaaga agttgacagc
    19441 tttgacacct atgtttacac agatgttccc ttacagagct ttatcaatgg cctaacagga
    19501 atcacatctg acaagattgc tgcggaacca aaagtagagg aggttatggc tgcgtttaaa
    19561 aattttgtgg gagagttacc actgattggt tataatgctc aaaaatctga cctgcctatt
    19621 ctagctgaaa atggcttgga tttaagggac caataccaga ttgacctctt tgatgaagct
    19681 tacgatagac gtagcgcaga cttaaatggg attgctaacc ttcgtctgca aacagtggca
    19741 acctttttag gcattaaggg tcgaggtcat aatagcttag aagatgccag aatgacagca
    19801 gtaatctata agtctttttt agaaacagat acaaacaaag catatctcag ccagcaagaa
    19861 gaggtaacca cagataaccc tttcgcagct ttgggagact ttttcgacta aaggctctgc
    19921 tatttttgaa aaataaaaaa attcctaggg ttagcccttg cttataacgc taggtcatgt
    19981 aagatagggg catatcaaga gggagtcggg tgcacacgag ttgcttttga tcactaaatg
    20041 atagaaagaa ggtgtggaaa tgtctcaatt ctattcgact ggagaattgg ccaacttagc
    20101 tggcgtttct attcgaactg tccaatacta tgaccaacgt gggattttga ttccgacagc
    20161 attgacagca ggtggacggc gactctatac ggattctgat ttagaacaat tacgcatgat
    20221 ttgctttctg cgcgatttgg gattttccat tgagcagatt cgcaaagtct tagcagagga
    20281 aaatgcagcc caggtgctgg aattgcttct agttgatcat attgcgactg ccaaggaaga
    20341 cttggctgca aaagagcaac aagttgacat agctgtcaag atacttgaca gacttcgaaa
    20401 acaagacccc cagtcactag attttctgat ggacatttcg cttagcatga aaaatcaaaa
    20461 agcttggaaa aaattacaat ggaagatggg tatcagtata tttttagcca ttgtttcata
    20521 tgtaggactt attttactat ctagttatct gcaaaaattt tggttagttt atgttgctat
    20581 gggactattt ctaccaggtt tcagttggtt ggtaatttat tttaggaagc aatttattta
    20641 tctctgtccc cattgtcatc agaaatttga acctagcttt aatgaatttg cccttgcagg
    20701 ccatacacca cgaaccagaa agttaacctg ctcccattgc catcaaaaat cgtattgctt
    20761 ggaactggca aaagaggaca ctgtctcaag aagataagca ctaactcata aaaaaactag
    20821 cctgagatcc ttctcaagct agtttttgtt tttttagaat ggtaatttac cagcaaaagc
    20881 gcctaatgtt ttcttagttg tttcatcaat ttgcgtaagg gcatcattaa tggcttgagt
    20941 ggtcatgtct tgaagcgttt ctacatcttc aggatctaca acagcttctt tgaagtcaat
    21001 cccaaccaat tttttatcac ccgtgaaagt ggcagtgaca aggtcttgag ctgattttcc
    21061 agtaaattgc atagcagcca aatccgcctg cttttgctcc atttgtttct gaagcttttg
    21121 tgcttgcttc atcatgtttt gcatgttcat cataagacta tactctcctt aatttaatac
    21181 taactattat aacacataaa aagaggcaat aaaaacaatg tcagttagta gactagcctg
    21241 tatcagtaag aaagtcgcta tggataagat ggattagcag caagggtctg gctaatgaca
    21301 gaataagtct agaaatgaac tatttttgtc atagactagt ccgacttagt ggttatctaa
    21361 ttcacgatct tctttagctt gttgttctaa aagaatttgt gcgaagtcaa cccacttagt
    21421 gtagttattt tcggataatt gttctgaaat catcgctaac tctcgttgtg gcaactgata
    21481 agagactccc ttattttcta aggttaaatc ttcttccatt agggcggtta aactaacatc
    21541 aaagatagca gcaatatcac ttaatagacc agactttgga gtatattttc ctttttccca
    21601 ctcactgatt gaagaagagc tttttcgtcc taggagatta gcaagttcta attgttccat
    21661 gttctttttt aatctaaggt actttaaatt acttgcaaaa aaagttttct tggcggacat
    21721 atttttctcc ttttctttat ataaaatatg ataccataaa agaggttaaa gcaaaaggta
    21781 tcgtaaaaga tggtctaaaa actctctaaa aacttgactt cataaaaacc gaagtttata
    21841 ataaacttaa catgattaac taatctcatt ttagtgtgga gggaaaattg tgaccaaatc
    21901 aactttaaaa gagttaagaa caacaaagaa aatgacacag caggaattgt ctcacttaac
    21961 aggtatttct gtcagaacga ttgctaggta tgaaaaagat actaaaaagc taaggcgagc
    22021 aaaatatgag aagctaaaag gtattgcaca agcattagcg gtttccgttg atgatatttt
    22081 tttaggaata gattcggaat ttatgaacta agacgatcgt tttctgtttg ctattagtaa
    22141 gaccaattaa caaaaaagtg cttagttata ttgctaagca cttttctttg ttaatttgat
    22201 gctattggca caatcaattg agactgactg agatcgatag ttaaagcata gttgctgttg
    22261 tcacggacag tatgttcaaa atcggttgtg tataagatga ctcgaagggt atctcctttt
    22321 tctagatgat agatggttgg ttgcaaagga agtctaacag tcatccattt attattagga
    22381 atagtttcaa ttgacgacaa attattgcga ttttgtaaat tcatgaaacc tttcgaaata
    22441 acacggtaag aatcttctct aaatggtagc tctttaaggg gttccctaga gaaattttgc
    22501 ccattgtcaa tacttgattg ggtgagagca ataggaagat cgcccaagcg ttttttctta
    22561 ccatagtcaa ggatttgtgc agatagaagt cctttatttt cacttgattt cacttttaac
    22621 tgtaggacaa tttcaccgtt aataggtaag tcctcttcca gtaaaatatc aatcagggct
    22681 tgattggcct tgcctttaaa gagagctgct ttgaacgcac ggaaatcttt accgtaagct
    22741 ttaaattcat cttcaccata gtgattatca attaaaagca gttcctgacc gaggtcaagc
    22801 tctttgatgg ttgaggttcc aaagacttta cgctcctgcc agttttgtgg gcaggtgtta
    22861 tcctgccaga tcatttcagg aaggctaaaa tcattagcta ggcctaagag tttttgacat
    22921 aaaagggcat tcatgctttc gcgaaaatca atggattgcc aattatgcat gtaaacatgc
    22981 tcaccttgat gtaaaaagag gtgcttgttg attgtggaag gaagcgcatt gaaaatctca
    23041 tagacctgtc ttggtttgac attccagtct tgtaagccat gagtataaac gacatcacac
    23101 tttatttgat gagcattttt taagtaattg cggtcgtgcc aaaattgatt ataatcacca
    23161 gattgtcggt ctaacgcctg agactgttgg tttagcaatt cttgataacg atcattatgg
    23221 cgaagataat cgccagccaa taaattacgc gagtaggtga gctcagttag gacatctaga
    23281 tcctctccag gatagccacc aggactacaa actaagccat tttcgcggta gtagttgtac
    23341 caagaagaaa tagctgattc tgcaataatc atggctaatc cgtctacgcc tgtagtggct
    23401 aaaccagtag acatagttcc caagtaggac tttccagtcg tacaaactag accatttgcc
    23461 caatcagctc tcacttggtg ggtttttgag tggctggtgt aggctgtggc tcttccattt
    23521 agccaatcaa taacggcttt aaagctttca atttgagcat agtttccact cgtcataaag
    23581 ccagtggaac cagcagttcc cacacctgaa acatagatat tagcaaaccc acgtgcgagg
    23641 aaataatcgt tgaggctata ggagttaatg tagctaaagc tttctagatt ttgacctata
    23701 ggaagtttgc aaggctgtgt ctcaagagga ataaaatccc tgtcttcgac agtgatttgt
    23761 ctcctttttt taacgactaa ctctttttcc atacgataaa gttttttgtc gttggctact
    23821 tcattgatac cttgatggta tggactaggt gtcatcaaag ttggtaatgg tttttgagat
    23881 ggaggacgaa tgatattaac cttaataaga tcaagttggc catcttgatc ggtatcaaga
    23941 ggtgcttcaa cgtaaacaac ttctcgaatc agctgtgacg tgtcaaaggt agctaatgat
    24001 ttaccgttga agaagtggta atcattgtcc atagtaagca ttccttggct gaccaaatca
    24061 tcaatcaggg tcatgccaga cttacaacgg gtcgctaata agtggtggat atgcttgata
    24121 atttctgttt cgtcaaagtg gataggaaag gccagtttat caaggaaagc atcggcctct
    24181 gtaaaatcaa ctccaggaat aaagccaagg acttgcaggg ccagtaaatc aaaaacctct
    24241 ttggataact cttgctctga ttgaaaaaag ctcaatgcgt ccatgtcatt tttggcgatt
    24301 agatgactta aaggataatc actatcaggg tagtggaaga agagtttacg taaaaagctt
    24361 tctaggctag ctttggcagt tttttgcaga tccagatcaa agcccaattc ttttaattct
    24421 tcagccgctc tttctagact agttggaata taggaaaatt gattatagcg cataggagtt
    24481 tcctttctag tggcttagaa aacgatatta tcttttaatt tatcaagatt ggtaatgata
    24541 atatgttgtt tatcaatgcg aatgatgttt ttttctttca actgttttag aatacggctg
    24601 acgctgctag cggtagaaat gccacagaat ttaccgagtt cctcattagt aatgacaaaa
    24661 ttaattaaaa tttggccatt tggtagttct tcgccaaata gggtcattaa gtcatatatt
    24721 tgagtagaaa tggcaccgat acggccgtta gttaacatac attgcatttt tttcatggat
    24781 ttttgaagac gattatggta aaagtccttc acatatcctt gtagttcaat atcttcgttt
    24841 atatctttta aaaatgctga gcggcgaacc ttgtaaaaac tagctttctc tgactcgatg
    24901 cgaacattat aaggctctcc catatctttt gaataaccag tgttgagaac agaagtaatt
    24961 tcaagtcctg taacatatct caaattaaat tccattccat attttgaaag aacactctgt
    25021 ttcacaatgc cgtcttttaa aatataagtg aagtcctctt cgagactttc aaaagtcaag
    25081 tacttgtgat aacttttttc aatgatagga aagttatgat tatcaatata ccgttgcaaa
    25141 atgtgatgat tcacgctttt ctccaaatat tcttttacca atgtataatt tgtatcttca
    25201 agagaaatta acatttgcta atgccctttg
//
LOCUS       DAUGQX010000028        24281 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUGQX010000028 DAUGQX010000000
VERSION     DAUGQX010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24281
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.028"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..180
                     /locus_tag="VIA51_001111"
     CDS             <1..180
                     /locus_tag="VIA51_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEQ8683055.1"
                     /translation="DSLTRQVKNIYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEW
                     IGDAIVHVESKLNAR"
     gene            183..707
                     /locus_tag="VIA51_001112"
     CDS             183..707
                     /locus_tag="VIA51_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEQ8683056.1"
                     /translation="MNIEEAKRAIRELEAFNYFDFKGNLIKRIDVLGIIDQLGQPKVV
                     VPKPVFEMIKFRKEHDQDLTTTFVNIHAYPDNVFHWVANNGDLFAQAWLAYPNITIEK
                     EKLYTVEIPNPNREGRGHAKFVLERQGNKVFLVKRKSKDCYYNKNSNHLTESEIRKDF
                     DWAWREGFAEEVTE"
     gene            704..970
                     /locus_tag="VIA51_001113"
     CDS             704..970
                     /locus_tag="VIA51_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683057.1"
                     /translation="MKEKTIFISKKYANDFNNDKYNLSSGYYFKNGEQHDIAIVKYGE
                     QDYLKNTDLAYVVCDKIVDGESIGFVYHGEYETWRFKLLNTEAN"
     gene            1256..1690
                     /locus_tag="VIA51_001114"
     CDS             1256..1690
                     /locus_tag="VIA51_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEQ8683058.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPYGTPSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLAPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGVLLAEKGVFS"
     gene            2300..2680
                     /locus_tag="VIA51_001115"
     CDS             2300..2680
                     /locus_tag="VIA51_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683059.1"
                     /translation="MARANKAKMLDAIEFKLLNPTANQAQVAEIIGITDRQLRNWEND
                     PEDKSGWNKLNDEIAEKAFGKYALSAIGTLVNLSKNAKSELVRLQASQDILDRAGYKP
                     TDKQEISIDEPIVLANSWVQDNGS"
     gene            2670..3944
                     /locus_tag="VIA51_001116"
     CDS             2670..3944
                     /locus_tag="VIA51_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8683060.1"
                     /translation="MVVDLADIIPIGFKPVVQATWNPQILNIACKGGRGSGKSSNIAF
                     IISRLIIQYPVNAVCIRKTDNTLEQSVYEQIKWAISEQGLERYFKFNKSPLRITYIPR
                     GNYIVFRGAQNPERIKSLKDSRFPFAIGWIEELAEFKTEDEVKTITNSLLRGELGDGL
                     FYKFFYTYNPPKRKQSWVNKKYESQFQPSNTFVHASTYKDNPFIAKEFIAEAEATRER
                     SERRYRWEYLGEAIGSGVVPFDNLRFERITDEQVADFDNIRNGIDYGYATDPLAFVRW
                     HYDKKKNGIYAIDEYYGQKISNRQLAKWLTTKGYQSDEMFAESAEPKSNAELKNEFGI
                     KRIKGVKKGPDSVEFGERWLDDLDFICIDPKRTPNIAREFENIDYQVDRDGNPKPRLE
                     DKDNHAIDATRYAMSDDMRATKTIVKTFKGGI"
     gene            3944..5269
                     /locus_tag="VIA51_001117"
     CDS             3944..5269
                     /locus_tag="VIA51_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8683061.1"
                     /translation="MPELFIVPSDTEMTKDLLSELIQKHRSFNLSYSAYKQLYEGDHA
                     ILQQKQKEQYKPDNRLVVNFAKYIVDTFNGYFIGVPVQTSHENKQVSNYLELLDGYND
                     QDDNNAELSKICSIYGHGYELVFNDENAEVGITYLTPLEGFIVYDDSIRQKPLFAVRY
                     FYNKDGVLEGSYSDASKITYFKDGEKDLEIGESDPHPFDGVPMIEYVENEERQSLLAS
                     VVTLINAFNKAISEKANDVEYFADAYLKILGAELDDETLKSLRDTRIINLKDTDAQQL
                     TVEFLQKPDADATQEHLLDRLENLIFRTAMVANISDESFGTASGIALRYRLQAMDNLA
                     KTKERKFMSGMNRRYKLIASYPTSKIGPKDWIGIKYKFTRNLPANLLEESQIAGNLAG
                     IVSEETQVGVLSIVENPQKEIEKKNSDRPTLISRKAGGLNGQDTTTVLE"
     gene            5238..6146
                     /locus_tag="VIA51_001118"
     CDS             5238..6146
                     /locus_tag="VIA51_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ8683062.1"
                     /translation="MAKTPQQYWNERQKQLWANLETSERALQTKLSKYYADEAKSLEK
                     EIGAYFSKYGKDNVIEYRNLLQQLSKADKDLLYRDCERFAKKYPQRADLMPVRTSIYK
                     LDRLQGLELSIKIQQLEIGAIEEAELTKHLTTAFKKGYQETAKTIGFQADKVSAELFV
                     NNDWTGKGDFSSSIWSNKDKLVDYLTNDFKTAIIRGDSFDKVVKQMSERFTVRSQSDI
                     TRLIMTEGTYVNNQAMMAPFEDSDDFEEYEFVSVLDSSTSSICRGLDGHKFKLKDRQV
                     GVNFPPMHANCRSTFAMVIPDDYLER"
     gene            6153..6422
                     /locus_tag="VIA51_001119"
     CDS             6153..6422
                     /locus_tag="VIA51_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683063.1"
                     /translation="MNKRIKKKRKLETAIVMIVAENAMQAEALRNQNKEIMELKSIVQ
                     RNALATNEELATVKAATLDNQSAIKSIGDDVDYIKQNYKRKWRKK"
     gene            6667..7236
                     /locus_tag="VIA51_001120"
     CDS             6667..7236
                     /locus_tag="VIA51_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8683064.1"
                     /translation="MENEEILEQSGAQEEAKEQTFDDILSDPKKQAEFDKRVAKAIDT
                     ARNKWVAETEEKENEAKRLAKMNAEQKAQHEKAKLEARIAELEAERTLSEMKSAARTM
                     LSEANINISDALLSQLVSTDADKTKNAVEAFSEAFSEAIEKEVKERLKSPTPKKSNGN
                     TGLTKEQILAVKDTAERQKLIAENIGLFQ"
     gene            7255..8145
                     /locus_tag="VIA51_001121"
     CDS             7255..8145
                     /locus_tag="VIA51_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ8683065.1"
                     /translation="MVTSRTYPEENLIKSTDLKYPITIDVTNKFQENISKLLEMLGVT
                     RKISVSEGMTLKTYAGYDVTLAEGNVPEGEVIPLSKVERKIHSEKKIELKKYRKATTG
                     EDIQMYGSNEAVTNTDNALVRQLQKKIRTDFVTALKTGTGTQDALGAGLQGALASAWG
                     KLQVLFEDYGSERAIVFANSLDVAEYIAKAGITTQTAFGLTYLVDFTGTVIISTNDVT
                     KGEIWATVPENIIFAYINPNNSELAKEFNLYGDPTGYIGMNHFQENTTLTIQTLLVSG
                     MLMYPERIDGIVKVTLTPGV"
     gene            8158..8451
                     /locus_tag="VIA51_001122"
     CDS             8158..8451
                     /locus_tag="VIA51_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEQ8683066.1"
                     /translation="MAYRVKARFFDLLDNSFLYEVGDSFPRKGYEPSKERLESLLSSN
                     NTEHKPFIEVSGNGNSLDGLKVDELKAKAAELGIELPSNAKKAEIIELLQAHI"
     gene            8465..8809
                     /locus_tag="VIA51_001123"
     CDS             8465..8809
                     /locus_tag="VIA51_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683067.1"
                     /translation="MDETKQAIIDRVRVRLADETSLKEELLEELTQTAIDRINLKVGD
                     VVFNPLFNSIAVDVVVKMYRRMYFEGIDTEKADTISTKFIENVLAEYGEELASYKKDR
                     LAILNKKVVRFL"
     gene            8806..9117
                     /locus_tag="VIA51_001124"
     CDS             8806..9117
                     /locus_tag="VIA51_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683068.1"
                     /translation="MMFVNFDLVTSQKTGEKDRLGNDITKNVVKRVAKGRFTEWSADD
                     VSLYGRDLTSSARKLLTNQVSKAEAKQASHVVIDGSKYKVESVKDLGRWRLLVIKGYR
                     L"
     gene            9114..9509
                     /locus_tag="VIA51_001125"
     CDS             9114..9509
                     /locus_tag="VIA51_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683069.1"
                     /translation="MRMSMTGMPALEVKLRSMSEKRWDRVANKNLTEMFNRAARPPGT
                     PIGKNTKRHKSGELLRSRRLKKVNSSKDVITGNFGYIKDYAPHVEYGHRIVRNGKQVG
                     YANGTKYLFNNVKKQREIYRQDMLNELRR"
     gene            9511..9921
                     /locus_tag="VIA51_001126"
     CDS             9511..9921
                     /locus_tag="VIA51_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5072 family protein"
                     /protein_id="HEQ8683070.1"
                     /translation="MLKKLGLVDLHASIKQKIEDKTGLMAYDHVPEDMPSPFYFIEVV
                     DKRPEDTKVMWCEVFTVWIHAIAEAGKSKIAIYDMIEKLEEALTEELVLPEEIDILRQ
                     SEVGMQSLQEDETGEMHAIVAYEIKVSYGFKVKV"
     gene            9933..10439
                     /locus_tag="VIA51_001127"
     CDS             9933..10439
                     /locus_tag="VIA51_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8683071.1"
                     /translation="MVAFDQNVYCNFDTSATKAIAGKDIILAIFDKTGANLLAISGQQ
                     GLTINRTADSIEVSSKDTKGGWKSKIPGMKEWSIDNDGLYVPSDETHKQLGEAFEKSE
                     FVCIKVINGKTKKGMFGGLASVSDYSLEAPYDDGMTYSISLEGNGALIDLSTLSSEDA
                     EKVTAMPS"
     gene            10452..10769
                     /locus_tag="VIA51_001128"
     CDS             10452..10769
                     /locus_tag="VIA51_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683072.1"
                     /translation="MDKELIIIDEKQYELKYNEKTIETVEALTGKAFMDVIVNNKGML
                     SLSMLRQYFANALYAVEGGRVSSEQGSNIFTKVLNTKGYAYVNMLVINTIQRDCPFFF
                     LGA"
     gene            10742..11200
                     /locus_tag="VIA51_001129"
     CDS             10742..11200
                     /locus_tag="VIA51_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683073.1"
                     /translation="MPFFLPRRLVDFEYLGGSGDSTDVEYDRLASQYHKDIDFAFYFV
                     NFGTTKSEFLELTRREKAFIRKAWEDKQVRESELMRNAVLNAVSNAMRKKSAKFVDLW
                     KRQQQPANMEIVEAHLEIINKNIADEGKYWVDLVYQANNMTKPSEGAENG"
     gene            11193..12998
                     /locus_tag="VIA51_001130"
     CDS             11193..12998
                     /locus_tag="VIA51_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8683074.1"
                     /translation="MADYTLGVQITGDASKMQKAFEKAQEQAEKLKEKIKDSNNESGN
                     SFDGLTTKIDAISGKLSAYGDKISSIGKNMTTMFTLPAVAGITAVVKEYANLEQSIGG
                     VETLFKKSAKAVQKNANTAFRRAGVSANEYMEQVTSFSASLISSLGGDTAKAVGVADT
                     AMVDMSDNANKFGTNIGLIQNAYQGFAKGNYTMLDNLRLGFGGTKEEMQRLLDEAGKL
                     SGMEFDINNFSDIIQAIHIIQDNLGVTGTTAREASETISGSFSQAKASVIDFMGSLGG
                     DGSDVDAKMQAMIQSITVFADNVKEALGRIWDNLPLQEYQKNLLLIAVVGGPILVVVG
                     TIFGAIANIMTVVSGILTVLGMMTPIGWIIAAAIAAIVAAVVFWDDIVAEVGQKFELV
                     KIIGMAMWESFKDGVSSFGKSIQNVVGKIGGWFAEAWNAAADTATRIFTKVGDTISGI
                     FSGVVSGIKSLINGAIGGINKVIGITNKLPGVNIPKIPYLARGTSDWQGGFARINEGG
                     RGELVHMPNGATVVPHDVSMKYARESAKANSGVAYMDSNDEIAKSALKLANDAVKRPV
                     VLNINGREVAKTTGGDMRDYLNSRDMTLKRLRGEV"
     gene            12999..14483
                     /locus_tag="VIA51_001131"
     CDS             12999..14483
                     /locus_tag="VIA51_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEQ8683075.1"
                     /translation="MATMTFNDVDLSSLITIMSINRDIGNERQADTNDAPFIGLHIKK
                     IKTSAKIITVDFYLKDRTNEYALNQLKHKLAGIFNVNEQVKVTFSDEPDKYYLAIPIN
                     KISASDPIAWLSLVSLELLVPDGVAHSVSYKKITNYRQDGKKLLIDITNNGNVDAHPI
                     ITVKHNAENGYLAFVNKSSVFEVGDREIADAEIREKSVVAYDFKDERIVNALTAGKKN
                     VAILNDSTQVLDKNLLLNTVWGRKHLELEGSVAPSGNHAGTLTFDIPDGGSLYDYLWW
                     RQIFWVGTVSQLGFIKIMVSDENGHFLYGVETIKRTLGTKTEYNFLVTNGKGGYKITD
                     LRWTFDATHFETQNPFNEPRGWSDMTRADDTVSVFWWGSQNKRVFPELKGKKSKQVHI
                     AIGTIQGSPLVTHMYIDGFYYRKDKVPYEFNIPNAFGAGTEVVINAENDTVLVDNIPK
                     ANIIADGFFSFPKIPPGTSTLEVYSSSWSTANPDITLNFEERWL"
     gene            14484..17924
                     /locus_tag="VIA51_001132"
     CDS             14484..17924
                     /locus_tag="VIA51_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8683076.1"
                     /translation="MLITIHNANLEKVAYIDNDKQDTLNYYDDKFSQYLNTANSTFEF
                     TVYKRGIKSDTVKEKAYLTLTERSFVSFKYNGKSYLFNVMTTDETDIEIRCYCENLNL
                     ELLNEYAGPYKAATQMSFVDYCNLFGILKNGAITIGTNETTDQKRTIEWTGQDTNLKR
                     LLSIANNFDAEIEFVTHLKNDSSLKSFVMNVYKKNDATNQGVGRRRDDIILQYGKNIE
                     SVRRKINKTGIYNAIRPSGKITTTTTTTTAKQGSVQTGSVLWSGGNLTYAGHVMQSSV
                     VNTILSLCSKYKLLPSGVFSQLYLESFWGDTPVGRADNNWGGITWTGATTRPSGINVS
                     QGQSRAEGGYYNHYASVDDYLKDYAYLLAEQGIYAVKGKLTIDEYTRGLFRVGGATYD
                     YAAAGYDHYAPLMRDIRAGINRNNNGAMDNVDNQFKNGGSTSQNTTQIAAKTKAVLAE
                     ANGLKGQRVGSGQCYALAAWYAMKLDGPGLNGGVTSFRGLIGAGAAAAQIGTDYNWGQ
                     FGWKVVQPNKVADLITGSIVNIRANAGSPVFTGAWGHTVVVKSLSGDTLTVLEQNYNN
                     VQTVQEHTYSASAYLSVVQTVCYPPEIVQGKRVEGTAQAEQPQSETTTISEEKEVLIN
                     PSLYREWKNEAGQVEFYVKNSMLYAPLSKSLYPSAFTGIETDDNWIRKDLDVDTESEE
                     KLISVALADLRKHCYPAVTYEVSGFIGDLDIGDTIKINDPEYTPSLILEARVSEQHIS
                     FTEPNQNKTVFDNYRALESKVSQGLIDRMNELAEAAKPYDLRLMTDNGNVFLNGEGRT
                     ILTAELWKGNKKFDASYQFKRDGQLVGAGLQLAVDAKDVPADRPLIITVEAYLNNELI
                     ASKQITFTNSLGEQGPAGRGIVSTEDYYLASPNRTGVTSATSGWTKTPQEITETNKYH
                     WYYHVDVYSDGTRKETTPAIIGVYGDKGSDGKQGKRGEMGPSGPPGALDKKQLQDINN
                     KIDGKADQNLTIEQINKLAELQSIANAELQAKASIDALASLQKQVQSAIAAMNASQKL
                     SEQDLITASQRAIKATNDILDLKEQWNFIDNYMSASEEGLIIGSKDGTSSVRVAKDRI
                     AFYSAGAEVASITGGMLKIDNGMFVATLQVGHFREEMYKVDGVDKHINVTRYYETIVG
                     "
     gene            17929..19791
                     /locus_tag="VIA51_001133"
     CDS             17929..19791
                     /locus_tag="VIA51_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683077.1"
                     /translation="MAEFWSNNDRGYRIKLTIDQVSQNTLANSSQVRVKLDLLNTTTT
                     FTQYSCSAYVDLNGQRIDWSDSPSVLRYNSTISLIDRTITVNHNADGTKSFGFIASFS
                     GSGGWSPGTLTVGSGTFTLTTIPRSSSVVVSSGTIGSAITININRQSSSFKHNLRYQW
                     GNKTGTIASDVDTSAVWTIPLDFASDIPNSTSGSGTIYVDTYNDSTLTGTQQVPFTVT
                     VPDSMKPTLSSISLSDAHTVAGNVVSSADYFIQVYSDIRVNFESASGSYGSTIKGYYA
                     EIVDKGQSTDQNGGTLGNMLYDGQITIRAKVIDSRGRESQPMDKTVTVLKYFPPALSF
                     DVARSGYGSDTLTVTRRASIAPLSVFGTQKNTMTLSFSVAELGSSYFSANNGSASGAW
                     ANVSSLVNSSANLYGAFSPTKSYTVKGILSDKFSRTEFTFDVGTESVVMSIAKNGIGF
                     QKIWEKGAIDAKGDAYISGKLFVNNTEVKPSFDKTEILNMVYPVGAIYMSTSSANPST
                     FIGGTWQRYAQGRTIVGVSENETEFNYVGKTGGAKTHTLTNEEMPSHSHGDKTISSGG
                     RPISSNAGWDNTNVGLYKSTDYNQINAFNKSSGGDQPHNNLQPYITTYIWLRTA"
     gene            19802..20149
                     /locus_tag="VIA51_001134"
     CDS             19802..20149
                     /locus_tag="VIA51_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8683078.1"
                     /translation="MLVITSNYPEQMPDGSVSGAKVMLDGIDDHAGWHIPLTLLKEYL
                     DKPQSEVMTLCEKMIYQQLKPQKALNEKFAKLDATIEKGENMLKFATGILNQIIAAKE
                     EETTDDETVEKMD"
     gene            20299..20622
                     /locus_tag="VIA51_001135"
     CDS             20299..20622
                     /locus_tag="VIA51_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683079.1"
                     /translation="MTIDVTLFAQWCVALTAIIVFLKWVSAPVKHVLDNNKKAMEALE
                     SAIVKISDDLKDNNFKWTESKNHRDRLQKVQDQHEIRIGIVEDRLISHDEQLKTLWKV
                     KEEKK"
     gene            20622..20954
                     /locus_tag="VIA51_001136"
     CDS             20622..20954
                     /locus_tag="VIA51_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEQ8683080.1"
                     /translation="MEELIQVITGSALSILTIFAGIVVKLVKDYLLKKGGEKAVKIAE
                     IVARNAVEAVEQIAYDKDIKGIEKLTEAKIAVRDELSKHNVYLSDKQMEVFIEAAVKR
                     MNDSWKGQ"
     gene            20956..21720
                     /locus_tag="VIA51_001137"
     CDS             20956..21720
                     /locus_tag="VIA51_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8683081.1"
                     /translation="MATVSEVISYWRGLADTGQGYDADLAWGWQCADVTNGTTTNFFG
                     VTLWGNAIDLLDSAKAQGLEVIYDAPGINPKAGDLFVMFTYGHPYGHTGIIIADSDGY
                     TIQTIEQNVDGYSDNNGDGINDQFQVGGPARYVTRAFSDGDGYIVGWIRPPYSDTSSE
                     KQSQSQAPSGFRKLKDEVGTFEVMVPALNVRREPSLNGEIVACYQYGMTGTYDSVYVG
                     DGYIWVSYVGASGMRNYMAVGDADGDYNVNPYCKFY"
     gene            21732..22334
                     /locus_tag="VIA51_001138"
     CDS             21732..22334
                     /locus_tag="VIA51_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683082.1"
                     /translation="MGYNSTNLKQVDGGDVIKQGDTSSLFSFNLLDENNNVIDLNGKQ
                     ATIYFTRNRKTYLTKTTDVIDNKVDFTINKILEIGTYYIEVHCDGYVFPSDDSVTLDV
                     RRSGQKYVVSTDLITDTTIQKLSADIEYLKSKVTQNQHLFEQVSPQTEWTITHNLIKY
                     PSVTIVDSAGNEVFGSVEYISTTKIIVRFSAPFAGKAILN"
     gene            22345..23118
                     /locus_tag="VIA51_001139"
     CDS             22345..23118
                     /locus_tag="VIA51_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683083.1"
                     /translation="MSTFLTNINLNKNELQNAVVQNLAKEPHEPKSGQFYFDSAANNL
                     KIYNGTSWVVLDKETAESIVDLINSGKSKIDKSKVDGLEEAINQASMTGQAIATALNE
                     DTGGVTVNQNKITGLTDKLAEIATNKASATRESQDALQEAKVYADQKVAGLVDSASED
                     YNTFKELETFIKQNAKGLAAISNVAKKFSKTFGDARAKEFTITHNLKTRDVNVTIRET
                     NFPYAIVYADIKVTDENSILIATGAEVLTQNQYTVTITG"
     gene            23128..23349
                     /locus_tag="VIA51_001140"
     CDS             23128..23349
                     /locus_tag="VIA51_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683084.1"
                     /translation="MRYIGESQLSKDLVTKDYVDNKVTNLASKDDIVNLGKIKDSQTG
                     AFLEVKIVPNGQVPYDTTGMIVFERSGGK"
     gene            23349..24008
                     /locus_tag="VIA51_001141"
     CDS             23349..24008
                     /locus_tag="VIA51_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683085.1"
                     /translation="MSVQEIPDKIFYRLIEQTVEAKLVWDKDTQIGSYYISIHDKYSF
                     ESGRDVNIYKILSSTQADVYKANKYNYQSSSKPDTSVPQPKPPEQPPLKNKSLYQSIT
                     IDGLPIARVICNNQVIWSQSAEPQEVYNITAYVDASVSKLNDSAIIDYNRDFAAYGVN
                     WSRVDRVAVEVDDKIVAKLQAPVYDFGVRGGTTMSVEKWDYPSNTIDKYKNPTFKILQ
                     H"
     gene            complement(24130..>24281)
                     /locus_tag="VIA51_001142"
     CDS             complement(24130..>24281)
                     /locus_tag="VIA51_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8683086.1"
                     /translation="KFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEV
                     YLTTK"
BASE COUNT         8130 a         4310 c         5292 g         6549 t
ORIGIN      
        1 gactctttaa caagacaagt taaaaacatt tattttttgc aaaatacaaa agacgacatg
       61 ctgagtttta gtgatattaa cgttatgcca agaactcaag atattgagcg agaatttaat
      121 gtcaaagagt ggattggtga tgcgatagtg catgtagaga gtaagttaaa tgcgaggtaa
      181 aaatgaacat tgaagaagcg aaaagagcga taagagaact agaggcgttt aattatttcg
      241 attttaaagg taatttaatt aaacgaattg atgtattagg tatcatcgac caactcggcc
      301 aaccaaaagt ggtagtgccg aagccggtat ttgaaatgat taagtttaga aaagaacacg
      361 accaggattt aacaacaact tttgttaata tacatgctta tccagacaat gttttccatt
      421 gggtggcaaa taacggtgat ttatttgccc aagcatggct agcttatcca aatatcacca
      481 tcgaaaaaga gaagctatat acagtggaga taccaaatcc gaacagggaa ggcagaggtc
      541 atgccaagtt tgtgcttgaa agacaaggta ataaagtttt tttggtaaaa cgaaaatcaa
      601 aggattgcta ctacaataaa aacagcaatc acctcactga atccgaaatt cgtaaagatt
      661 tcgactgggc atggcgagaa ggatttgcgg aggaggtgac ggaatgaaag aaaaaacaat
      721 ttttatatca aaaaaatatg caaatgactt taacaatgac aaatataatt tgtcctctgg
      781 ctattatttt aaaaatggtg aacaacatga tattgctatt gttaaatatg gcgaacaaga
      841 ttatttaaaa aatactgatt tagcatatgt tgtatgcgat aaaatcgttg atggagaatc
      901 tataggcttc gtttatcacg gcgaatatga aacttggcgt tttaaactat taaacacgga
      961 agcaaattaa attcccgcgc aagcgctcaa gagcctgcga tggctctgtg ggggtggacc
     1021 gaaattaaaa aatagaaacg agaacctcct tacaccaaaa caaatctaaa gcgggttatc
     1081 ggtcatccgt gattatccaa ggcgtcgcta atgctttaac acgacatcgt gcgcctgtgt
     1141 caaaaaacaa aggaaagaga ggacttttct ccacaaaaca aaaagacgtc catacggaac
     1201 gcccccttgg ttaaatttaa gcttaaataa attataccac attggggggg ctttcatgac
     1261 gttttttcca gagattgata tccaaaaaac aaaatctaat gccaagcgta aattgagaga
     1321 gtatccacgt tggcgaagga tagctaatga tgtagatact caaaaagtga cagccactta
     1381 ttcctttgag ccaagacaac cgtatggaac gccaagcaag cctgttgaga gactagcgct
     1441 caaccgtgtg tcagcagaac aagagctgga tgcgattgag caagccgtca gtatgatact
     1501 agagccagag agacgcagga ttttgtatga caaatactta gcgccttata aaaaggcaga
     1561 taaggttatt tatacagaat tgtgtatgtc agagagcttt tactatgata cacttgacat
     1621 tgctttgtta gcttttgcag agctgtacag agagggtgtg ttgcttgctg agaaaggagt
     1681 ttttagctag tttttataca gtaataagat agtttataca tatttttaca tgttattata
     1741 gtattatcaa aataacaaga agagataacc ttttaatcac tgactatttt atttagtcgc
     1801 caactttaac tacaatcaaa cttgttattt tgtagcctga tggcggtaca gcgagttgag
     1861 acgacaactg ggtatgcagg ttcgattcct gccgtctcaa tcagcgccca gaagaggcgc
     1921 gacccagtat cccgaaaggc agtcacgcac tgatatactg gtttttactt ggttgatagt
     1981 catattccta ccaatgacga ttgataaaaa agatacatag atcggctgta tagtctacgt
     2041 gtacgtattc acaacagatt gactcatttg attaaccgca agtaaaacaa gggtcgcaac
     2101 cttgcctgtg gttagtaggc ttaatggtcg tttatgcacg ttcgattcgt gcaaagcctg
     2161 tttgataaat agaagtgtcc cagaatgggg taggcaatag gcttagcatt catttgctat
     2221 ttatctatgg ttaaccaatt agtcatcaca ttgtggtgac ttttttattt ccgaaaattt
     2281 ccgaaaggag gaacatattt tggcaagagc aaataaggca aaaatgcttg atgctattga
     2341 gtttaaatta ttaaatccaa ccgctaatca agcacaagtt gcggaaataa tcggtatcac
     2401 agacagacag ctacgaaatt gggaaaatga cccagaagat aaatcgggtt ggaataaatt
     2461 aaacgatgaa atcgcagaaa aagcttttgg caaatatgct ctttctgcga ttggaacgct
     2521 tgttaatcta agcaaaaacg caaaatcaga attggtaaga ctacaagctt ctcaagatat
     2581 ccttgaccga gcaggttata aaccgacaga caagcaggaa atcagcatag acgagcctat
     2641 cgtacttgct aattcatggg tgcaagacaa tggtagttga tttagctgat attatcccaa
     2701 ttggttttaa gcctgtcgtg caagcgactt ggaatcctca aatactaaat atcgcttgca
     2761 aaggcggacg tggttctggt aaatcatcta atattgcttt tattatctcg aggttaataa
     2821 tacagtatcc tgtcaatgcg gtttgtatcc gtaaaacaga taatactctg gagcagtctg
     2881 tttatgagca aattaaatgg gctatatctg agcaagggct agagcgttac tttaaattta
     2941 acaaatcacc tctaaggata acgtacatcc ctagaggtaa ttacattgtc tttagaggag
     3001 cacaaaatcc tgaacgtatc aagtccttaa aagatagtcg ttttcctttt gctatcggtt
     3061 ggatcgagga gcttgcggaa tttaaaaccg aggacgaagt caaaactatc actaactccc
     3121 tattgcgtgg ggaactcggt gatggtcttt tttataaatt tttttataca tacaatccac
     3181 ctaaacgtaa acagtcttgg gttaacaaaa aatatgagag ccaatttcag ccgtctaata
     3241 cgtttgtaca cgcatctacg tataaagata atccttttat tgccaaagag tttatagccg
     3301 aggcagaagc cacgagagag cgttcagaac gtcgttatcg ttgggagtat ttaggagagg
     3361 ccattggttc gggtgttgtt ccatttgaca acttacgctt cgaacgtatt actgacgaac
     3421 aagtagccga tttcgataat atccgtaacg gtattgacta tggttatgca actgacccgc
     3481 ttgcttttgt acgttggcat tatgataaaa agaaaaatgg tatctatgct attgacgagt
     3541 attatggtca gaagatatca aacaggcagc tggctaagtg gttgacgact aaaggatatc
     3601 agagtgatga gatgtttgct gaaagtgctg agcctaaaag taatgctgag cttaaaaacg
     3661 agtttggcat caaacggata aaaggcgtta aaaaaggacc agattctgtc gagtttgggg
     3721 agcgctggtt agatgactta gattttatct gtatagaccc aaaacggaca ccaaatatcg
     3781 ctcgagagtt tgaaaatatc gactatcaag tcgatagaga tggcaaccct aaacctcgtt
     3841 tagaagacaa ggataaccat gcgatagatg cgacaaggta tgctatgtca gacgacatga
     3901 gagcgactaa aaccatcgtc aaaacattta aaggaggtat ctagtgccag aattatttat
     3961 tgtgccatca gatacagaga tgacaaaaga tttgttaagc gagttaatcc aaaaacacag
     4021 gtcgtttaac cttagttatt cagcgtataa gcagctatat gagggtgatc atgctatttt
     4081 gcaacaaaaa caaaaagagc aatacaagcc tgataatcgc ttggttgtta attttgcaaa
     4141 atacatcgtt gatacattta acggctattt tatcggtgtg ccagtccaaa cgagccacga
     4201 gaataaacaa gtcagcaatt atttagagtt attagacgga tacaatgatc aagacgataa
     4261 caacgcagaa ctatcaaaga tttgcagtat ttacggacat ggctatgaat tagtttttaa
     4321 tgacgagaat gcagaggttg gaattactta tctgacgcct cttgaaggat ttattgtcta
     4381 tgacgactct attagacaaa agccgttatt tgctgtgcgc tatttttata ataaggacgg
     4441 tgttttagag gggtcttatt cagacgccag caaaatcact tattttaaag atggcgaaaa
     4501 agaccttgaa atcggggaga gcgatccaca tccgtttgat ggtgtgccaa tgattgagta
     4561 tgtcgaaaac gaagagcggc aaagcttgct agctagcgtt gtgacattaa ttaatgcgtt
     4621 taataaagct atctccgaaa aagccaatga cgttgagtat ttcgcagacg cttatcttaa
     4681 aattttgggt gctgagctag acgacgagac attaaagtct cttagagaca cccgcattat
     4741 caatctaaaa gacaccgatg cacagcaatt aactgttgag tttttacaaa agccagatgc
     4801 cgatgcaacg caagagcatt tgctcgaccg actagagaac ttaattttta ggactgctat
     4861 ggttgctaat atcagtgacg aatcgttcgg tacagctagc ggcatcgctt tacgttatcg
     4921 tttgcaagct atggataact tagctaagac aaaagagcgt aagtttatga gcgggatgaa
     4981 ccgcagatat aagcttattg caagctatcc tacgtctaag ataggaccta aagattggat
     5041 tggcattaag tataaattta ctcgcaatct accagcaaat ctcttagagg agtctcaaat
     5101 tgcaggcaat ttagcgggga ttgtctcgga agaaacacag gtcggtgtgc tatctattgt
     5161 ggaaaaccca caaaaagaaa tcgaaaagaa aaatagcgac aggccaacct taattagtcg
     5221 aaaagcagga gggctaaatg gccaagacac cacaacagta ttggaatgag cgccagaagc
     5281 aactatgggc taatttagag acgtcagagc gcgctttaca gactaagctt agcaaatatt
     5341 acgctgatga agcaaagtcc ttagaaaagg aaataggggc ttattttagc aagtatggaa
     5401 aagacaacgt tattgaatat cgaaatcttt tgcagcagtt atctaaagct gataaagact
     5461 tgctttatcg agattgtgag cgatttgcta aaaaatatcc acaacgtgct gatttaatgc
     5521 ctgtcaggac ctctatttat aaattagata gactgcaagg actagaatta agcattaaaa
     5581 tacaacagtt ggaaataggt gctatcgaag aggcggaatt gactaagcat ttaacgacag
     5641 cctttaaaaa aggttatcaa gaaaccgcta aaacaattgg tttccaagcg gataaagtat
     5701 ccgctgagct gtttgttaac aatgattgga caggcaaagg tgattttagc tcaagtattt
     5761 ggtctaacaa agataagctt gtcgattatc taacaaatga ctttaagacg gcaattatca
     5821 ggggagatag ctttgataaa gtcgttaaac agatgtcaga gcgttttact gtacgttcgc
     5881 agtcggatat tacacggctg atcatgacag aagggactta tgtcaataat caagcgatga
     5941 tggcaccgtt tgaggatagt gacgactttg aggagtacga atttgtctcg gttttagata
     6001 gctctactag ctcaatttgc agaggattag acggtcataa atttaaactt aaagatagac
     6061 aggttggggt taacttcccg cccatgcacg ctaactgtcg cagcacattt gctatggtta
     6121 ttccagatga ttatttagag aggtaaaaat ggatgaataa acgcattaag aaaaaacgta
     6181 aattagaaac agctattgtg atgattgttg cagagaacgc catgcaagca gaagcactca
     6241 ggaatcaaaa caaagaaatc atggagttaa aatcaatcgt tcaacgaaac gctctggcaa
     6301 caaacgaaga gttagcgact gttaaagctg ctactttaga taaccaatca gccatcaagt
     6361 caatcggcga tgatgttgac tacatcaagc aaaattacaa acggaagtgg aggaagaaat
     6421 aatatggtgt tagagcaagc tgaactagaa atggttagaa atcaacgtct ggttatgatt
     6481 aaccctgaaa tggtaactat cacaaaaaca gaatatgatc tgttgattga aataaaaaac
     6541 aaatttttag agtcgtagca atacggcttt ttattatgtc ctgtcgcatg acaaaaaact
     6601 aggcaaataa aaatctaaag caatgcgctg gggcttttga gcaatggcgt ggggcaggag
     6661 gaaaaaatgg aaaacgaaga aatcctagaa caatctggtg cacaagaaga agctaaggag
     6721 caaacgtttg acgatatttt gtcagaccct aaaaagcaag ctgaatttga caagcgtgtg
     6781 gctaaggcta ttgatactgc acgaaataaa tgggtggctg agactgaaga aaaagaaaac
     6841 gaagctaaga gacttgcaaa aatgaatgct gaacaaaaag cacagcacga aaaagcaaaa
     6901 cttgaagcac gcattgcaga gctagaagct gaacgtacat tgtcagaaat gaagagtgct
     6961 gctcgcacaa tgctatcaga agctaatatc aacatctctg acgcactttt atcgcaattg
     7021 gtatctactg atgcagataa aaccaaaaat gcagtagaag cgttttctga ggcattttcc
     7081 gaagcaatcg aaaaagaagt caaagaacgc cttaaatcgc caacacctaa aaaatcaaat
     7141 ggcaatactg gactgacaaa agaacaaatt ttagcagtca aagatactgc ggaacgacaa
     7201 aaactcattg ccgaaaatat cggcctattc caataaaaca ggagaaatta acacatggta
     7261 acatcacgta cttacccaga agaaaatcta atcaaatcaa cagaccttaa ataccctatc
     7321 actattgatg tcacaaacaa attccaagaa aatatctcga aattacttga aatgctcggg
     7381 gttactcgta aaatctcggt atctgagggt atgaccctta agacatacgc tggttatgat
     7441 gtcacattag cagaaggtaa cgtcccagaa ggcgaagtta tcccgttatc aaaagtagag
     7501 cgcaaaatac actctgagaa aaaaatcgaa cttaaaaaat atcgtaaagc aacaaccggc
     7561 gaagacatcc aaatgtatgg ctctaacgaa gctgtaacaa atactgacaa cgcacttgtt
     7621 cgtcagttgc aaaagaaaat ccgcacagac tttgtgactg ctcttaaaac aggtacagga
     7681 acacaagatg ctcttggtgc aggattgcaa ggggctttag cttctgcttg gggtaaactg
     7741 caagtgctct ttgaagatta tggttcagag cgtgcgattg tgtttgctaa tagccttgat
     7801 gtcgctgaat acatcgctaa agctggcatc actactcaaa ccgcattcgg attgacttac
     7861 cttgtcgatt ttacagggac ggtcattatc tcgacaaacg atgtcacaaa aggggaaatc
     7921 tgggcgacag taccagaaaa tatcatcttt gcttacatca atccaaataa ttctgaatta
     7981 gctaaagaat ttaatcttta cggtgatcca accggctaca ttggaatgaa tcacttccaa
     8041 gaaaatacaa cgcttactat ccaaacgttg cttgtatctg gtatgttgat gtacccagaa
     8101 cgtattgacg ggattgttaa agtaactctt acaccaggcg tctaatgggg gtagcttatg
     8161 gcttatagag taaaagcacg tttttttgat ttgcttgaca atagcttttt gtacgaggtt
     8221 ggcgacagct ttcctcgcaa aggctatgag ccaagcaaag agcgcttaga aagcttgtta
     8281 tctagcaaca atacagaaca taaaccattt attgaggtgt caggtaatgg caatagctta
     8341 gatggtttaa aagtggatga gttaaaagct aaagcggcag agctaggaat cgaactccca
     8401 agtaatgcta aaaaagctga aatcatcgaa ttactgcaag cacacatcta gaaagtaggt
     8461 tgacatggac gaaacaaaac aagcaattat tgatcgtgtc cgtgtccgtt tagcagacga
     8521 aacgtcttta aaagaggagt tattggagga gttaacgcaa acggctatcg accgtattaa
     8581 tttaaaagtc ggcgatgtcg tttttaaccc tctttttaat tccatcgctg ttgatgttgt
     8641 tgtcaaaatg tatcgtcgta tgtattttga aggaattgac acggaaaaag cagacacaat
     8701 atcaactaaa tttattgaaa acgttttggc agaatatggc gaggagttag cgtcatataa
     8761 aaaggaccgt ctagccatct tgaataaaaa ggtggtgcgg tttttatgat gtttgttaat
     8821 tttgacttag taacatcgca aaaaacggga gaaaaagaca gactcggcaa cgacatcacg
     8881 aaaaatgttg tcaaaagagt tgctaaaggt cgttttactg aatggtcggc tgatgacgtg
     8941 tccttatacg gtcgagattt aacgtctagc gcacgcaaat tgctgactaa tcaagttagc
     9001 aaggcggaag ccaaacaagc gtcacacgtt gtaatagacg gctcaaaata caaagttgaa
     9061 tccgttaaag atcttggtag atggagacta ctcgtcatta aagggtatcg cttatgagga
     9121 tgtcaatgac aggtatgcca gccttagagg taaaactaag gtcaatgagc gagaagcgct
     9181 gggatagggt tgccaacaaa aaccttacag agatgtttaa cagagcagca agacctcctg
     9241 gtacaccgat tggtaaaaac actaaaaggc ataagtctgg cgagttgttg cgctctagac
     9301 gtctcaaaaa ggtaaactca tcaaaagatg ttatcacagg taactttggt tatatcaagg
     9361 actatgcacc tcatgtcgag tatggacaca ggattgtccg caacggcaaa caggttggct
     9421 atgcaaatgg tacgaaatac ctgtttaata acgtcaaaaa acagcgtgaa atttataggc
     9481 aagacatgct aaacgaattg aggagatgac atgttaaaaa agttgggact ggttgattta
     9541 cacgcctcaa ttaaacaaaa aatcgaagat aagacagggt tgatggctta tgatcatgtc
     9601 ccagaagaca tgccatcgcc cttttatttt atcgaggttg tggataaacg gccagaagac
     9661 acaaaggtca tgtggtgcga agtgtttacg gtttggatac atgccatagc ggaagctgga
     9721 aaaagcaaaa tcgctattta tgacatgatt gaaaaactcg aagaagcgct cacagaagaa
     9781 ttagttttgc cagaagaaat cgacattttg agacaatcag aagtcggcat gcagtcctta
     9841 caagaggatg agactggcga aatgcatgca attgtagcct acgaaatcaa ggtttcgtac
     9901 ggttttaaag taaaagttta aaaggagaaa taatggtggc atttgaccaa aatgtttatt
     9961 gtaattttga cacatcagca acaaaagcta ttgcaggtaa agacattatc ttggcaatct
    10021 ttgataaaac tggtgcaaat ttacttgcta ttagtggtca gcaagggtta acaatcaacc
    10081 gtacggctga ctcaattgaa gtatcgtcta aagatacaaa gggtggatgg aaatctaaaa
    10141 tccctggcat gaaagaatgg tctatcgata atgatggtct ttacgtgccg tcagacgaga
    10201 ctcacaaaca attgggcgaa gcttttgaaa agagcgagtt tgtttgtatt aaagttatta
    10261 acggtaaaac caaaaaaggc atgtttggag ggcttgcgtc ggtaagtgat tatagcctag
    10321 aagctcctta cgatgatggt atgacatact caatcagtct cgaaggcaat ggagcattga
    10381 ttgatttatc aacattatca tcagaagatg ctgaaaaagt aacggctatg cctagttaat
    10441 gagaggaatg aatggataaa gaattaatta ttattgacga aaaacaatac gaactaaagt
    10501 acaacgaaaa aaccattgaa accgtcgaag ctttgacagg taaagcgttt atggatgtta
    10561 ttgtgaataa caaaggtatg ttgtcgctat ctatgttgcg tcagtacttt gctaacgctc
    10621 tttatgcggt agaaggcggt cgtgtgtcta gcgagcaagg ctctaatatt tttactaaag
    10681 tgttaaatac aaaaggttat gcgtatgtaa atatgctagt gatcaacaca atccagcgtg
    10741 attgcccttt tttcttcctc ggcgcttagt cgactttgag tatctcggcg ggtctggcga
    10801 tagcacagat gtagagtatg acagattagc aagtcagtat cacaaagata ttgactttgc
    10861 tttttatttt gtcaattttg ggactacaaa atccgaattt ttggaattaa ccagacgaga
    10921 aaaagccttt atcagaaaag cttgggaaga taaacaggtg cgagaaagtg agcttatgcg
    10981 caacgctgtt ctaaatgcag tcagtaacgc tatgcgcaaa aaaagcgcta aatttgttga
    11041 tttgtggaaa cgtcagcaac agcctgcgaa catggaaatc gtcgaagcgc atttggaaat
    11101 cattaataaa aacatcgctg atgaaggcaa atattgggtt gatttagtct atcaagctaa
    11161 caacatgaca aaaccgagcg agggggcaga aaatggctga ttatacttta ggagtacaaa
    11221 taacaggtga cgcctctaaa atgcaaaaag cgtttgaaaa agcgcaagaa caagctgaaa
    11281 aattaaagga aaaaattaaa gactcaaaca acgaatctgg caattctttt gatggtttga
    11341 ccactaaaat tgacgcaata tctggcaagc tgtcagctta cggagataaa ataagctcta
    11401 ttggcaaaaa catgacaacc atgtttacat taccagcggt tgctggtata acggcagttg
    11461 ttaaagagta tgcaaatctg gaacagtcaa ttggtggtgt tgagacttta tttaaaaagt
    11521 ctgccaaagc tgtgcaaaaa aatgcaaata cagcgtttag acgagctggt gtatctgcta
    11581 atgagtacat ggagcaagta actagctttt ctgctagtct aatttcatct cttggcggag
    11641 atacagcaaa ggctgtcggt gttgctgata ctgccatggt cgacatgtct gacaacgcta
    11701 ataaatttgg tacaaacatc gggttaatcc aaaatgccta tcaaggcttt gctaaaggca
    11761 attacacgat gttagataac cttagattgg gttttggtgg gacgaaagag gagatgcaaa
    11821 gattgctgga cgaagctggt aagctaagcg gcatggaatt tgacatcaat aacttttcgg
    11881 acattataca agcaatccac attatccaag ataatttagg cgtaacagga acgacagcta
    11941 gagaagcgtc agaaactatt agcggctcat tttcgcaagc aaaagcgtca gtaatcgatt
    12001 tcatgggttc tcttggcgga gatggcagtg acgtagatgc aaaaatgcaa gcaatgatac
    12061 agtcgattac tgtgtttgca gataatgtca aagaggcttt ggggcgtatt tgggacaatt
    12121 tgcctttaca agagtatcaa aaaaacctct tgcttatagc tgtcgttggc ggacctatcc
    12181 ttgttgtggt cgggactatt tttggagcta ttgctaatat catgactgtt gttagcggta
    12241 ttttaaccgt tttaggcatg atgacgccaa taggatggat catagcagca gccatagcgg
    12301 ctattgtcgc agctgtcgtt ttttgggacg atattgttgc agaggtcggc caaaaatttg
    12361 agttagtcaa aataatcggc atggcgatgt gggaaagttt taaagatggt gtatctagtt
    12421 ttggcaagtc aatccaaaat gtcgttggca aaattggcgg atggttcgcc gaagcgtgga
    12481 atgctgcagc cgacacagcc actagaattt ttactaaggt tggggatacg attagtggca
    12541 tctttagcgg cgttgtttct ggcattaaaa gtttgatcaa cggagcaatc ggtggcatca
    12601 ataaggttat tggcattacc aataaactgc ccggtgtcaa cataccaaaa atcccatatc
    12661 tcgccagagg tacatctgac tggcaaggcg gttttgctcg tattaacgag ggcggtcgtg
    12721 gagaattagt tcatatgcca aacggggcaa ccgttgtccc gcacgatgtc agcatgaaat
    12781 acgctcgaga atctgctaaa gctaattctg gtgttgctta tatggatagt aatgatgaga
    12841 ttgccaaaag tgctttgaaa ctagctaacg atgctgttaa acgccctgtt gtgttaaata
    12901 tcaacggccg tgaggtcgct aaaacgacag gcggagatat gagagattat ctaaatagtc
    12961 gagatatgac attaaaacga ttgagaggtg aggtttagat ggctacaatg acttttaatg
    13021 atgtggactt atctagcctc atcactatca tgtctattaa tcgcgacatc ggaaacgagc
    13081 gacaagcaga tactaatgat gctccgttca tcggattgca cattaaaaag attaaaacta
    13141 gcgcaaaaat cattacagtt gacttttatt taaaagacag gacaaacgag tacgcattaa
    13201 accagctaaa acataaacta gctggtattt ttaatgttaa cgagcaagtc aaagtaactt
    13261 ttagcgacga accagataaa tattatctag ctataccgat aaataaaata tcggctagcg
    13321 acccaatcgc ttggctaagc cttgtgagct tggaattact tgttcctgac ggcgtggccc
    13381 attctgtgtc atacaaaaaa atcacgaatt acagacaaga tggcaagaag ctactgattg
    13441 acattacaaa caacggtaat gttgatgcgc atccgatcat tactgttaag cacaacgccg
    13501 agaatggtta tttagctttt gtaaataaat catccgtttt cgaggtcgga gacagggaaa
    13561 tagcagacgc tgaaatccgt gaaaagtcgg tcgtcgctta tgattttaaa gacgaaagaa
    13621 tcgtcaatgc cttaacagca ggtaaaaaga atgttgctat cttaaatgac tcgacacaag
    13681 ttcttgataa aaatttatta ctaaataccg tctggggaag aaaacatctc gagttagaag
    13741 gaagtgttgc gccaagtggc aaccatgctg gaacgttaac gtttgatatt cctgacggag
    13801 gtagcttata tgactatctt tggtggagac aaattttttg ggttgggact gtttcccagc
    13861 ttggctttat caaaatcatg gtatcagacg aaaacggaca ttttttatat ggagtagaaa
    13921 ctataaaaag aacgttagga acaaaaacag agtataactt tttggtcact aatggaaaag
    13981 gtggatataa aataactgat ttacgttgga cttttgatgc tactcacttc gaaacacaaa
    14041 acccctttaa cgaacccaga ggttggtctg atatgacaag ggctgatgac actgtatctg
    14101 ttttttggtg gggttctcaa aacaagcgag tattcccaga attaaaaggc aaaaaatcta
    14161 aacaggtaca catcgcaatc ggcactattc aaggcagtcc tttagtaact cacatgtata
    14221 ttgatggatt ttattatcgc aaggacaaag taccgtacga atttaatatt ccgaatgctt
    14281 tcggggcagg aacagaagtc gttattaatg ccgaaaatga cacagtttta gttgataaca
    14341 ttccaaaagc taacatcatc gccgatggct tttttagttt tcctaaaatt cctcctggaa
    14401 catcaacatt agaggtttat tcctctagtt ggtctaccgc caacccagat attacgctaa
    14461 attttgaaga aaggtggcta taattgctta taacaatcca caacgcaaat ttagaaaaag
    14521 ttgcttatat tgataacgat aagcaagaca ccttgaatta ttatgacgac aaattttcac
    14581 agtatttaaa tacggccaat tcgacatttg agtttacggt ttataagcga ggaattaagt
    14641 ccgacacagt caaagagaaa gcctatctga cacttacaga aaggtctttt gtgtcgttta
    14701 aatataatgg caagtcttat ctgtttaacg taatgacaac agacgagaca gacatcgaga
    14761 tacgttgtta ctgcgagaac ctcaatctcg agttgctcaa tgagtatgca ggaccttata
    14821 aagcggcaac tcagatgtct tttgtcgatt attgtaattt gtttggcatc cttaaaaacg
    14881 gtgctattac cattggcact aatgagacaa ccgaccaaaa acgcacaatc gaatggactg
    14941 gtcaagatac caatcttaaa cgcttgttat ctatcgccaa taattttgat gcggaaatag
    15001 aatttgtaac gcatcttaaa aacgattcta gtcttaaatc gtttgtcatg aatgtctaca
    15061 agaagaacga cgctactaat cagggcgttg gtcgtagacg agatgatatt attttgcaat
    15121 atggcaaaaa tatcgagagt gtcagacgta agattaataa aacaggcatt tacaatgcta
    15181 taagaccaag cggtaaaata acaacgacta caaccacaac gactgctaaa caaggctctg
    15241 tgcaaacagg gtctgttttg tggtctggcg gtaacttgac ttatgcaggt catgtaatgc
    15301 aatcatctgt tgttaacact attttaagcc tatgtagcaa atacaaactt ttaccatctg
    15361 gtgtttttag ccagctatac cttgaatcgt tttggggaga taccccagtc ggaagagccg
    15421 ataataactg gggtggtatc acttggactg gcgcaacaac taggccaagc ggaataaatg
    15481 tctcccaagg gcagtctcgt gctgaaggtg gttattataa ccattacgcc agtgttgatg
    15541 actacttgaa agattacgct tacctcttgg ccgagcaagg catttatgcc gtaaaaggta
    15601 agctaaccat tgatgagtac acaagaggtc tgtttagggt cggtggcgca acatatgatt
    15661 atgctgcagc tggatatgat cattatgcac ctttgatgcg agacatcaga gcaggtatta
    15721 accgtaataa taacggcgct atggataacg tcgataacca atttaaaaat ggtggctcga
    15781 ctagtcaaaa cactactcag atagctgcta aaacaaaagc ggtacttgcg gaagcaaatg
    15841 gactgaaagg tcaacgagta ggctctggtc agtgctatgc gttagctgct tggtacgcca
    15901 tgaaattaga tggtccaggt ctgaacggtg gtgtaactag ttttagaggg cttattggtg
    15961 ctggtgctgc cgctgctcag attggtacgg attacaactg gggtcagttt ggctggaaag
    16021 ttgtacaacc gaataaagtc gcagacttaa tcacaggctc gattgttaac atcagagcaa
    16081 acgctggcag tcctgttttt acaggcgctt gggggcatac tgttgttgtt aaatctctat
    16141 ctggagatac actcacagta ttagagcaaa actataacaa cgtgcaaaca gtccaagagc
    16201 atacatatag cgctagcgct tatttatcag ttgtacagac agtctgttat ccgccagaaa
    16261 tcgttcaagg aaaacgcgtc gaaggtactg cacaagcaga acaaccgcaa tctgaaacga
    16321 ccacaatatc tgaagaaaaa gaggtcttaa ttaatccatc actttatcgt gagtggaaaa
    16381 acgaagcggg acaagtcgag ttttacgtta aaaacagtat gctctacgca cctctgtcaa
    16441 aatctcttta cccgtcagcg tttactggca tcgagacgga cgataactgg atacgaaaag
    16501 acttagatgt tgacacagag agcgaggaaa agcttatctc tgttgctctc gcagacctga
    16561 gaaaacattg ttatccagcg gtgacttatg aagtatctgg ttttattggt gatttagata
    16621 ttggtgacac tatcaaaatc aatgacccag aatatacccc aagtttaatt ttagaagcaa
    16681 gggttagcga gcaacacatc tcgtttacag agcctaatca aaataagaca gtatttgata
    16741 attacagagc tttagagagc aaagtctcac aaggtttaat tgatcgcatg aatgaactag
    16801 cagaagctgc taaaccttac gacttgcggt taatgacaga taacggaaat gtgtttttaa
    16861 atggcgaagg tcgtacgatt ttaaccgctg aactttggaa aggtaacaaa aagtttgatg
    16921 caagctatca atttaaacgt gatggtcaat tagtcggcgc tggattgcag ttggcagttg
    16981 acgctaagga tgtaccagct gatagacctc taatcattac tgttgaggct tatttaaata
    17041 atgagctgat tgcaagtaaa cagattacgt ttactaactc gcttggagaa caaggaccag
    17101 ctggacgtgg gattgtctct acagaggact attacttagc gtcaccaaat cgtacaggtg
    17161 tcacatctgc aacatctggt tggactaaga cgcctcagga aattactgag actaataaat
    17221 atcattggta ttatcacgtt gatgtttatt cagatggcac tcgaaaagag actacaccgg
    17281 ctattattgg tgtttacggc gataaaggtt cagatggcaa gcaaggcaaa cgtggggaga
    17341 tgggaccatc aggacctcct ggcgctttag ataaaaagca actacaagac atcaataata
    17401 aaattgatgg caaagcagac cagaatttga ccatcgagca aatcaataaa ttagccgagt
    17461 tacaatctat tgccaacgct gagttacaag caaaggctag catcgacgct ttagctagct
    17521 tacaaaagca agtacagtct gcaatagcgg caatgaatgc tagccaaaag ttatcagagc
    17581 aagaccttat tacagctagt caacgggcta tcaaagcaac caacgacatc ttagacttaa
    17641 aagagcaatg gaattttatt gacaattata tgtcagcgtc tgaagaggga cttattatcg
    17701 gctctaaaga cggtacaagt tccgtgcgtg ttgccaaaga ccgtattgcc ttttactcag
    17761 ctggcgcaga agtcgcttcg attactggtg gtatgctcaa aattgataat ggtatgtttg
    17821 tggctacttt gcaagttgga cattttcgcg aggagatgta caaagttgat ggggtagata
    17881 aacacataaa tgttacaaga tattacgaaa cgattgtggg gtgattaatt ggcagagttt
    17941 tggtcaaaca atgatagagg ttaccgcatc aaacttacga ttgatcaagt atcccaaaat
    18001 acattagcaa acagtagcca agtgagggtt aaacttgatt tgctaaatac aacaacaact
    18061 tttactcaat atagttgttc tgcatatgtt gacttaaacg gtcagcggat agactggtca
    18121 gactcaccat cagtacttag atataactca acaatttctc tgatcgatag aacaataaca
    18181 gttaatcata atgctgatgg tactaaatca tttggattta tcgctagctt tagcggctct
    18241 ggtggatggt ctccaggtac tttgactgtt ggtagtggta cttttacact tactaccatc
    18301 ccacgctcaa gctccgttgt tgtttcttct ggtactattg gcagtgccat cactatcaac
    18361 atcaatagac aaagctctag ttttaagcac aacttgagat accagtgggg taataaaaca
    18421 ggtactattg caagcgatgt ggatacttcc gccgtttgga ctatccctct tgattttgct
    18481 agtgacatcc caaactcaac aagtggtagc ggcactatct atgtagatac ctacaatgac
    18541 tcaacgctaa ctggtactca acaagtgcca tttaccgtaa ctgtaccaga cagtatgaag
    18601 ccaacattat caagtattag cttgagtgat gctcataccg ttgcaggcaa cgtagtatca
    18661 agtgcggatt attttatcca agtatactct gacattagag tcaattttga atcggcaagt
    18721 ggctcttatg gttcgacaat caaaggctat tatgctgaga ttgtcgataa aggacagtct
    18781 actgaccaaa acggcggaac gctaggcaac atgctttatg atggtcaaat cactatcaga
    18841 gcaaaagtta ttgatagtcg aggtcgtgaa tcgcaaccca tggataaaac agtcacggtg
    18901 ctcaagtact ttccgccagc tttgtcgttt gatgttgcaa ggtctggtta tggttctgac
    18961 acgctaacag ttacaagacg agcgtctatc gctccgttaa gtgttttcgg aacacaaaaa
    19021 aataccatga cgcttagttt tagtgttgca gaattaggtt ctagttattt ttctgctaat
    19081 aacggctctg caagtggggc atgggcaaat gtttctagtt tggtaaactc gtctgccaat
    19141 ctttatggtg ctttctcgcc gacaaagtct tataccgtca aaggtatctt gtctgacaaa
    19201 tttagtcgca cagagtttac gtttgacgtc ggaacagaat cagttgtgat gtcaatcgct
    19261 aaaaatggca tcggattcca aaaaatttgg gaaaagggtg ctattgacgc taaaggagat
    19321 gcttatatta gcggtaagtt atttgtcaat aatacagagg ttaaaccgtc gtttgacaag
    19381 acagagattt taaacatggt ttatcctgtc ggagctattt acatgagcac atcatcagcc
    19441 aatccatcaa catttatcgg cggcacttgg caaagatatg cacaaggtag gactattgtc
    19501 ggtgtctccg aaaacgagac ggaatttaac tacgttggta aaactggtgg agccaagact
    19561 catacattaa ccaatgaaga gatgccaagt cacagtcacg gggataagac tattagctcg
    19621 ggtggtagac ctatctcatc aaatgctggt tgggacaata caaatgttgg tttatataaa
    19681 tcaacagatt acaatcaaat aaacgctttt aacaagtctt ccggaggtga tcaaccacat
    19741 aacaacttac aaccatacat cacaacgtac atttggctga gaacagctta gaggagaatt
    19801 tatgttagtt atcacatcaa attacccaga acaaatgcct gatggttccg tatctggtgc
    19861 gaaggtgatg cttgacggga ttgatgatca cgctggttgg catatcccgt tgacattact
    19921 aaaagaatat ttagacaaac ctcaaagcga ggttatgaca ctttgcgaaa agatgattta
    19981 tcaacaatta aaaccacaaa aagcattaaa cgaaaagttt gctaaactcg atgcaaccat
    20041 tgaaaagggt gaaaatatgc ttaaatttgc gactggaatt ttaaatcaaa ttatcgcagc
    20101 aaaagaagag gaaacaacag atgatgaaac tgttgaaaaa atggattaaa aggagatata
    20161 tcatgatgat taattatttc gcaatgcaaa ttgagtttgg ttggattact ttggaagatg
    20221 tacctaaaaa atatcgtgac aaagtaaaac agcttgttga atcagggaat atcggaacag
    20281 aataacgaga ggccttatat gacgatagat gttacactat ttgcgcaatg gtgtgtagcg
    20341 cttactgcaa taatagtatt tttaaaatgg gtgtctgcac ctgtcaaaca cgttttagac
    20401 aataataaaa aggctatgga agccttggaa agtgctatcg tcaaaatatc tgacgactta
    20461 aaagacaaca attttaaatg gacagaatcc aaaaaccatc gtgacagact acaaaaagtc
    20521 caagatcaac acgaaatcag aatcggaatc gtagaagata gacttattag tcatgacgag
    20581 cagctaaaaa cgctctggaa agtgaaagag gaaaagaaat aatggaagaa ttaatacaag
    20641 ttatcactgg ctcagcacta tcaattttga caatctttgc aggtattgta gtcaagttag
    20701 tcaaagatta tttgcttaaa aagggcggag aaaaagcggt caaaatcgcc gaaattgtgg
    20761 ctcgcaatgc cgtggaagca gttgagcaga ttgcttatga caaagacatc aaaggcattg
    20821 aaaaactgac agaagctaaa attgcggttc gtgacgaact gtctaaacac aatgtctatt
    20881 tgtcagacaa acaaatggaa gtctttattg aagcggctgt taaacgcatg aacgacagtt
    20941 ggaaaggtca ataatatggc aacagttagc gaagtaatta gctattggcg tggattagct
    21001 gatacaggtc aaggttatga tgccgacctt gcgtggggct ggcaatgtgc tgatgtgact
    21061 aatgggacaa ctactaactt ttttggagtg acgctttggg gaaatgcgat tgacttacta
    21121 gatagcgcga aggcgcaagg gttagaggtt atctatgacg cccctggaat aaatcccaaa
    21181 gctggtgatt tgtttgtgat gtttacttac ggacatcctt atgggcatac aggaattatc
    21241 attgctgata gcgacgggta cactatccag acgattgagc aaaatgttga tggctactca
    21301 gacaataacg gtgacggcat taacgatcag tttcaagttg gcggaccagc tcgctatgtc
    21361 actcgtgcct tttcagacgg cgacgggtat atcgtgggtt ggattagacc gccttatagc
    21421 gatacctcat ctgaaaagca atcacaatca caagcgccat caggattccg gaaattaaaa
    21481 gacgaggtcg gaacatttga ggttatggtc ccagcgctaa acgttcgccg tgaaccaagc
    21541 ttaaatggcg agattgtagc ttgttaccaa tacggcatga caggaactta tgattctgtc
    21601 tatgttggcg atgggtatat ttgggtgtct tatgtcggtg catctggcat gagaaattat
    21661 atggctgttg gagacgctga tggcgattac aatgtcaatc catattgtaa attttattaa
    21721 aagggggtta tatgggatat aactcaacca accttaaaca ggttgacggt ggcgatgtta
    21781 tcaaacaagg tgatacatcg tcacttttta gttttaattt gttggacgaa aacaacaacg
    21841 ttattgattt aaatggcaaa caagcgacta tttactttac acgtaatcgc aaaacctatc
    21901 taaccaaaac aactgatgtt attgacaaca aagttgattt tacgattaat aagattttgg
    21961 agattgggac atactatatc gaagtgcact gcgatggcta tgtctttccg tctgacgaca
    22021 gcgtaacgct tgatgttaga cgttctgggc aaaaatatgt cgttagcact gatttaatca
    22081 cagacacaac tatccaaaaa ctatcagctg atattgagta tttaaaatca aaagtgactc
    22141 aaaatcagca tctatttgag caagtgtcac cacaaacaga atggaccatt acacataatt
    22201 tgattaagta tccatctgtg acaattgttg atagtgcagg taatgaggtt tttggaagtg
    22261 tcgagtacat tagcacaaca aaaatcatcg ttagattctc agcgccattt gctggcaaag
    22321 ccattttaaa ttaaaggaga ttacatgagt acatttttaa caaatatcaa ccttaataaa
    22381 aacgagttgc aaaatgcagt cgtacaaaat ttagctaaag aaccgcatga accaaaatca
    22441 ggacaatttt attttgacag tgctgctaat aatctaaaaa tctataatgg gacatcttgg
    22501 gttgttttag acaaggaaac agcagaaagc attgttgacc ttattaattc tggtaaatcc
    22561 aaaatcgata aatcaaaagt cgatggactt gaagaagcaa ttaatcaagc gtctatgact
    22621 ggtcaagcta tcgcgaccgc tttaaacgaa gatactggtg gcgttactgt aaaccaaaat
    22681 aaaattacag ggcttacaga taaactagct gaaattgcga ctaacaaagc gtcagcgact
    22741 cgggagtcac aagatgcttt gcaagaagcc aaggtgtatg ctgaccaaaa agtagccgga
    22801 cttgttgata gtgcatcaga agattacaac acgtttaaag agctagaaac ttttattaaa
    22861 caaaacgcga aaggtctcgc agcaatctca aatgtagcca aaaaatttag taaaacgttt
    22921 ggcgatgcac gagctaaaga atttacaatc acacacaacc taaaaactcg tgatgttaac
    22981 gtcactatcc gagagactaa cttcccttat gcaatcgtct acgcagatat taaagtcaca
    23041 gacgaaaata gcatcttaat cgcaacaggt gcagaagtat taacgcaaaa tcagtatact
    23101 gtgacaatta ctggatagga ggccgctatg agatatattg gcgaatcaca actctcaaaa
    23161 gaccttgtaa caaaagatta tgtagataac aaagtgacta atctcgcgag taaggatgat
    23221 attgttaatt taggtaaaat taaggactcg caaacaggtg cgtttttgga agtcaaaata
    23281 gtcccaaacg gtcaagtccc ttatgacacc actggcatga ttgtgtttga acgctctgga
    23341 ggtaagtaat gtcagtacaa gagataccag ataaaatttt ttatcgatta atagagcaaa
    23401 cagtagaggc aaagctggtt tgggataagg acacacaaat aggtagctat tatatatcca
    23461 tacacgataa gtatagtttt gaatctggta gagatgttaa catctataaa atcttatcta
    23521 gcacacaggc tgatgtgtat aaagctaata agtataatta tcaatcatca tcaaaaccag
    23581 atactagcgt accacagccg aagccaccag agcaacctcc gctcaaaaac aagtctttgt
    23641 atcaatcaat cacgattgat ggactgccaa tagctcgcgt tatttgtaat aatcaggtca
    23701 tttggtctca atcagcagag cctcaggaag tttacaacat tacagcgtac gtagatgcta
    23761 gcgtatctaa gctaaatgac tctgccatta ttgattacaa tcgagatttt gcggcttacg
    23821 gcgtaaattg gagtcgagtt gatagagtcg ccgttgaagt cgacgataaa atagttgcta
    23881 agctacaagc tcctgtctat gattttggtg ttagaggtgg cacgacgatg tctgtcgaaa
    23941 aatgggatta cccatcaaat acaatagaca aatacaaaaa tccaacattt aaaattttgc
    24001 agcattagga ggtaaagctc ctttagataa gacaaaaccg ctcatcaaat gagcggtttt
    24061 tacattaata aaagaattgc aataaaattt ctaaatccag cagtaggtaa ggttgccaaa
    24121 agcaaaaagt tacttggttg ttaggtagac ttcaatttgg cttgtgtttg agtcaagcgt
    24181 ttcattatct ttatatatca taagatattt agattgagta aattctggtt cagggaaaaa
    24241 atcaaaccaa aaactttctt tattcttagg tatgaacttt a
//
LOCUS       DAUGQX010000029        23540 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUGQX010000029 DAUGQX010000000
VERSION     DAUGQX010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23540
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.029"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            134..1348
                     /gene="sstT"
                     /locus_tag="VIA51_001143"
     CDS             134..1348
                     /gene="sstT"
                     /locus_tag="VIA51_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEQ8683087.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASKETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMLFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(1403..2077)
                     /locus_tag="VIA51_001144"
     CDS             complement(1403..2077)
                     /locus_tag="VIA51_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEQ8683088.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(2087..3478)
                     /locus_tag="VIA51_001145"
     CDS             complement(2087..3478)
                     /locus_tag="VIA51_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEQ8683089.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSLEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFEKPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(3548..4261)
                     /gene="rsmG"
                     /locus_tag="VIA51_001146"
     CDS             complement(3548..4261)
                     /gene="rsmG"
                     /locus_tag="VIA51_001146"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEQ8683090.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKSLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            4411..4968
                     /locus_tag="VIA51_001147"
     CDS             4411..4968
                     /locus_tag="VIA51_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEQ8683091.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            5015..5911
                     /gene="htpX"
                     /locus_tag="VIA51_001148"
     CDS             5015..5911
                     /gene="htpX"
                     /locus_tag="VIA51_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEQ8683092.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            6145..6678
                     /locus_tag="VIA51_001149"
     CDS             6145..6678
                     /locus_tag="VIA51_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEQ8683093.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VCYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            6945..7631
                     /gene="covR"
                     /locus_tag="VIA51_001150"
                     /gene_synonym="csrR"
     CDS             6945..7631
                     /gene="covR"
                     /locus_tag="VIA51_001150"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEQ8683094.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            7637..9139
                     /gene="covS"
                     /locus_tag="VIA51_001151"
                     /gene_synonym="csrS"
     CDS             7637..9139
                     /gene="covS"
                     /locus_tag="VIA51_001151"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEQ8683095.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMVRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            9354..9848
                     /gene="nrdR"
                     /locus_tag="VIA51_001152"
     CDS             9354..9848
                     /gene="nrdR"
                     /locus_tag="VIA51_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEQ8683096.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            9832..11007
                     /locus_tag="VIA51_001153"
     CDS             9832..11007
                     /locus_tag="VIA51_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEQ8683097.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGDLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            11008..11910
                     /gene="dnaI"
                     /locus_tag="VIA51_001154"
     CDS             11008..11910
                     /gene="dnaI"
                     /locus_tag="VIA51_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEQ8683098.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            11973..13283
                     /gene="der"
                     /locus_tag="VIA51_001155"
     CDS             11973..13283
                     /gene="der"
                     /locus_tag="VIA51_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEQ8683099.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            13490..16588
                     /locus_tag="VIA51_001156"
     CDS             13490..16588
                     /locus_tag="VIA51_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8683100.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQALIEFLWRLASDTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            16831..17433
                     /locus_tag="VIA51_001157"
     CDS             16831..17433
                     /locus_tag="VIA51_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683101.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQTPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            17473..18801
                     /locus_tag="VIA51_001158"
     CDS             17473..18801
                     /locus_tag="VIA51_001158"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEQ8683102.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            18847..19329
                     /locus_tag="VIA51_001159"
     CDS             18847..19329
                     /locus_tag="VIA51_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8683103.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEEHIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            19441..21015
                     /gene="mltG"
                     /locus_tag="VIA51_001160"
     CDS             19441..21015
                     /gene="mltG"
                     /locus_tag="VIA51_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEQ8683104.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            21088..21570
                     /gene="greA"
                     /locus_tag="VIA51_001161"
     CDS             21088..21570
                     /gene="greA"
                     /locus_tag="VIA51_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEQ8683105.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(22193..23116)
                     /gene="yidC"
                     /locus_tag="VIA51_001162"
     CDS             complement(22193..23116)
                     /gene="yidC"
                     /locus_tag="VIA51_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8683106.1"
                     /translation="MKLTLNRILFSGLALSILLTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(23198..23476)
                     /locus_tag="VIA51_001163"
     CDS             complement(23198..23476)
                     /locus_tag="VIA51_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEQ8683107.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
BASE COUNT         7611 a         4016 c         4746 g         7167 t
ORIGIN      
        1 ttcgatagtc aatagaaatt gactgaaaat tcttagcaca aaaaatggtt aagatatgta
       61 gctcattcga tttgacgaat agatagaatt atattattat aaaaaacatg taactttagt
      121 aaggatgtaa cgtatgaaaa aaatatatga tttatgggtt agggttagtc taatcaaaaa
      181 aataggtatc ggtgttgtaa taggagtcat gttgggcatt ttggctcctg atcttacagg
      241 ttttagtatt ttaggaaagt tatttgttgg tggtttaaag gctatcgcac ctttgcttgt
      301 atttgctttg gtttcccaag ctatctccca tcagaaaaaa gggaaacaga ctaatatgac
      361 attaatcatt gttctgtatt tatttggtac ctttgcgtca gctttagtag cagtactgac
      421 agcttatcta ttccctttga cgttagtgtt aaatacacct gtaaatacag aattatcacc
      481 acctcaaggt gttgctgaag tttttcagtc acttctatta aaattagtgg ataatccgat
      541 caatgcttta gctactgcca attatattgg tgtgctatca tgggcaatta tttttggact
      601 agcattaaag gctgcaagta aagaaacaaa gcatcttata aaaacagcgg cagaagttac
      661 ttcacaaata gttgtttgga tcatcaatct ggcacctatt gggattatga gtctggtgtt
      721 cactacgatt tctgaaaacg gtgttggaat cttatctgat tatgcttttt tgatactagt
      781 tttagtagga acaatgcttt ttgtcgcctt agtggttaat ccacttattg cggttttgat
      841 tacacgacaa aatccttatc cccttgtctt gagatgttta cgtgagtcag gtcttacagc
      901 atttttcaca cgaagttctg cagccaatat tccagtcaat atgcaattat gccaaaaaat
      961 tggattgagt aaagatactt attcagtgtc aattccactt ggagcaacta ttaatatggg
     1021 tggggcagca attaccatca atgtcctaac gcttgctgct gtacacactt ttggtattcc
     1081 tattgatttt ctaacagccc tcttacttag cgttgttgct gctgtctctg cttgtggtgc
     1141 ttctggtgtt gctgggggat cgttgttact tattcctgta gcatgtagtt tgtttggcat
     1201 ttcaaatgat cttgcgatgc aggtggttgg tgttggtttt attgttggtg ttatccagga
     1261 ttcttgtgag acagccttaa attcgtcaac cgatgttctt tttacagcta ttgctgaaaa
     1321 tgctttttgg aaacgtaaaa aagcatagct agatttaaca tagtaaaaaa catccttgga
     1381 aaacgccaag gatgtttttt tattatttaa gatagccaag ataatcaaat ttttcaaagg
     1441 tgtggtcatt agcgatggcc acaatgatag tattcggttc taaaggttca aaaggtttga
     1501 cattagtatc taaggtttta acttcttttt gacgcatgcc aatcacattt aactcatatt
     1561 tacgacgaac atctagttcg gaaagagatt gtccttccca gcttttagga atgacaaatt
     1621 caatcatcga aataccatgt tccaaataga tgatgctttc gatatgacgt cttaacagat
     1681 ttgaagctac acgttttcca gaatcacgtt caggggtgat gactttagtt gctccgatgc
     1741 catatagaac ttcttcaaaa attttatttt tagccttggc aataatggtt ggaacaccga
     1801 gttttttaca gtgcatgact gcaagaacag aagattccaa gttattccct gaagcgataa
     1861 cgacagtatc acaatgttca atccctacag ctaatagaaa ttctttgtca gtaatatctc
     1921 caacagcggc tttagtgacc aagtcggcca cctctttgac atgactttct ctgatatcaa
     1981 tagcaataac gtcttgatca aagttactta attctctggc aacagtacgg ccaaaaatac
     2041 caaggccaag aacgccgaca gttttacgtt ttaacatgtt ttctccttaa cccactagaa
     2101 tatcagtagt ggcatattga atggtttttt cttttcgttg aatcagactg atgaggacag
     2161 taattgggcc aacgcggccg acgaacatca agacaatgac aataagacgt ccagcagtag
     2221 acaattgtgg tgtcaaatcc atagataccc caactgtcgc gatggcagaa atagattcaa
     2281 ataagagtgg tataggagcg atatgaggct ccacgctaag taataaaata aaacctatca
     2341 taagaactgc aaaaaagaag ataagaactg tcatggtctg cttaattgtc ttatttgcga
     2401 taattcggtt acgaaaggta acttctgatt gccctgaaag ttccgcttta aagagtaaga
     2461 aagtaatggc agcagtcgtc actttaatac caccagctgt tccaccagga gcaccaccaa
     2521 taaccatttg aatcatataa agaatgttag tcggtgctag ggtatcgtta taagagattg
     2581 ttgcaaagcc agctgttctc atagtgactg tttgaaaaaa tgaaaccata agttgctgat
     2641 gtaaactaaa attggcaatg gttttgctgt tatctttttc taaaaaccag gttaagaagg
     2701 ttccaagaaa aagaataaca gctgtggttt gtagtactag acgagactga ttggataatt
     2761 tacgaaaagt tgccccataa caatgaggtt tttcaaaaaa gtatttttta aaagctactc
     2821 ctaaatcaac ccaaaccgca aaaccaagtc caccagagat aatcaagaac gtaatgataa
     2881 catttaatgt aggatttaac ataaagtctt ttaaactaga agatcctaaa ttgtcaaaac
     2941 cagcgttaca aaacgccgac acagctaaaa aaatactatt gaagatacca tttttccacc
     3001 cgaagcgggg gatgaagtca atcatgataa ctatcgcagc aaaggcttct agactaaagg
     3061 ttactttata agcaaaaaaa aggtagtgct ttaaatcttt gctatcacct cgatttaacg
     3121 ctgattggag caaggtttga tcgctcaatc gcatttttcg cttgagggca aaagtactca
     3181 cagctattaa cgtcaccaag ccaagaccac caatctgcat tagtgccata gcaatggttt
     3241 gtccgatacc gttatacact tcagcgacgg gaacaacaga aagtccagtc acacaaacca
     3301 tggaaaccac attaaagaaa tgatcaagat agacggtatt aggaccattt tgataatggg
     3361 taaagggcat ggataacaag agagtcccaa tcagaatcac aatggcaaaa ctaaatgtta
     3421 agcgctgtgt gactgaaaga gatttgataa aagagcgttt catgtttcct ccagacataa
     3481 tatctcctac tataataaca aaaataagtt aaaaaagcta agtttcatct tagcctttgg
     3541 tactatttta tagaggtttt ttgttaggca agccagcttt tcttggatac ttgttaggtg
     3601 tttccttttt cttctcaaca atggtgatga agcgagaatc tccatttggc aattggtagc
     3661 tatggttttt aatgacttta ccaaaaagaa gacaaagagc attcttagct tcttctaact
     3721 cttggtcagc agcttgtgcc tttaaggcga ttaattttcc tccaattttt aaaaagggga
     3781 tggttaattc agatagaacc tgcatccgag caaccgctct ggcagtaaca acatcaaatt
     3841 gacctcgaaa ggccttgtcc tgtccgaaat cttctgctct accatgaaaa aagtggacat
     3901 tttccaagcc caattcctga gcaaggagtg tcagaaaaga aatccgctta ttaagagaat
     3961 caataatggt aacctcaagg tttgggaaaa gaattttcat gggtaggcta ggaaaaccag
     4021 ctccagctcc aatgtccaat aatttgattg gttcattagc taaaaagccc tgtaaaatag
     4081 gagcgatgga atcataaaaa tgcttgaggt aaacctcatt ttcttctgta atagctgtta
     4141 aattaatttt agtgttccat tccactagtg atttgaagta ggtgtcaaat tgttcttttt
     4201 gtttcgatga taaggaaaaa ccatcttcct ctagtgttcg gtaaaagtct tggggtgtca
     4261 tttgtatcct ctgtttttga tagttgttac cattctatca taaaatagcc tataacaaaa
     4321 tccaataaat catcagaaat aacacctcat tacttgctat tagcctagaa attgctataa
     4381 ttgagacaca aagattaaag gagacccact atgccaacag ttttgattat cttagtcgtt
     4441 ttaggagtgc ttgcgctatg gttaatgatt agttacaata gcctggttaa atctcggatg
     4501 cacacaaaag aagcttggag tcagattgat gtgcaattaa agcgtcgtaa tgacttgatt
     4561 ccaaatctta ttgaaaccgt aaagggatat gctagctacg agcaaaagac atttgaaaaa
     4621 atcactgatt tgcgtgcgcg tgttgcgaat gcctcaactc ctcaagaaac catggcggct
     4681 tctaacgaat tgagtaaaca agtgaccagt ttgtttgccg ttgctgaaaa ttacccagac
     4741 ttaaaagcta acgaaaactt cttgaaatta caagaagagt tgaccaatac ggaaaataaa
     4801 atctcatatt ctcgtcaact ctataattca acaacgtcta attacaacct tcaattagaa
     4861 tctttcccaa gcaatatcgc tggtaaatta tttggtttta aaccaagtga attcttacaa
     4921 acaccagaag ctgaaaaaga agttccaaaa gttgaattta acttttaaat atgaaattat
     4981 catctagtag gcaatcataa gagaaaggag aattatgctt tatcaacaga tttcacaaaa
     5041 taagcaacga acagttgttt tattagttgt tttcttcgct ctcttagcac ttattggagc
     5101 ttcagcaggc tatctgctgt tagataatta tgccatgggc ttggtccttg ctcttgtcat
     5161 tggggtgatt tatgctacca gtatgatttt tcaatccacc agtcttgtaa tgagtatgaa
     5221 caatgctaga gaagttacag aaaaagaggc tccaggcttt ttccatattg tcgaggatat
     5281 ggctatggtg gcccagattc cgatgccgag agtttttatt attgaagatc cttctttaaa
     5341 tgcttttgcg acaggatcta gccctcaaaa tgctgctgtt gcagcaacga caggtttact
     5401 tgaagtcatg aatcgtgaag aacttgaagg tgttatcggc catgaaatta gccacatccg
     5461 aaattatgat atccgtattt cgactattgc tgtagctttg gcgagtgctg ttaccgttat
     5521 ttctagtatc ggtgggcgta tgctatggta tggtggcggt tctcgcaggc aaagagatga
     5581 cggagatgat gatgttttaa gaatcattac attacttttg tcgttattat ctttgctttt
     5641 agcgccccta gtagcaagtt tgattcagtt ggctatttct cgtcaaagag aatatctagc
     5701 tgatgctagt tctgttgaac taacaagaaa tccccaaggt atgattaagg ctcttgaaaa
     5761 attgcagtta tctcagccaa tgaagcatcc tgttgatgat gctagtgcgg ccttgtatat
     5821 taatgagcct cgcaaaaaaa ggagcttcag ttcattattc agcacccatc ctcctattga
     5881 ggagaggatt gaaaggttaa aaaacatgtg agcgtttggg gtttttgctc aagcctcact
     5941 tttttatgtc tttgggcaga taatctaaaa tggcaggaat tatcaaaaat atctgaacaa
     6001 aaagaaaaaa atgagtgaaa caatggttaa aaatagaatg atttaaatct taaaattaaa
     6061 aaacgtcaga aaataaatgc aaaactattg acaaatcttt tagatagtag taaaaataaa
     6121 tgagagtttt attaggagaa gatgatgtta gctatttccg aaatcagaaa acacccagac
     6181 ggtctctcgt ttgatcgttt atgtgatgtc aaaagtatgt tacttgagcg tgaccaacag
     6241 attattgaca taaaggcagt taaagctgtc ggtaatgttt gctatgataa ggggctttat
     6301 ctgttagatt atcaattgag ttacgaagtg atattaccgt ctagccgttc tatggttccg
     6361 gtctgtttaa gtgaagtcca acacattcaa gaattattta tagaggcgac agatttagct
     6421 gataagaaag agttggttga agacaatctg gtattagttt tagacaaaga cgctattaac
     6481 ctcgaagaaa gtattgtgga taatatctta cttgctattc cgctacaggt cttgacagag
     6541 gaagaaaaga aatcaaaaga gttgccagca ggtcaaaatt gggcagtttt gacagaagaa
     6601 gactaccagt gtctaaaaga agaaaagcaa aaagaaaata atccttttgc tagcttgcaa
     6661 gggttgtttg atgaataaaa ctgaatatta aagatgtctg taatttttat ttgaaaaaac
     6721 agctattctt tgatatactc tttagagaat atggttactt atctaaagta gaaggtattt
     6781 tgaccataga gggcagagaa ggtaatgact attagatgct tcatatttta ttcgctagaa
     6841 gactatttga ccattagaac tgaaatagtc taggatatga gatgaatttc atagttttct
     6901 ttctgggaga aaaagataga ttaagaggat aagggttggt ataaatgaca aagaaaattt
     6961 taattattga agatgaaaag aatctggcta gattcgtttc tcttgagctg caacatgagg
     7021 gttatgaagt cattgttgag gtcaatggtc gtgaagggtt agaaactgct ttggaaaaag
     7081 agtttgattt aatcctgctt gacttaatgt taccagagat ggatggtttt gaagtgaccc
     7141 gtcgtttgca aaccgaaaaa acaacgtata tcatgatgat gactgcgcgt gattctatta
     7201 tggatgtggt tgcaggttta gaccgcggtg cagacgacta tattgttaaa ccgtttgcca
     7261 ttgaagaact acttgcccgt attcgtgcta ttttccgccg tcaagatatt gaatctgaga
     7321 agaaagtgcc tagtcaaggc atttatcgag atctagtttt aaatccacaa aaccgttcag
     7381 ttaatcgtgg cgacgatgag atttctctca ctaaacgtga atatgatttg cttaatattt
     7441 tgatgactaa tatgaatcgt gtcatgacac gtgaagaatt attgtcaaat gtttggaaat
     7501 atgatgaagc cgttgagact aatgttgtag atgtctatat tcgttatctc cgcggcaaaa
     7561 ttgacattcc aggcaaggaa tcttatatcc aaacagtgcg tggcatggga tacgttattc
     7621 gtgagaaata agtcatatgg aaaatcagaa acaaaaacag aagaaatata aaaattcgtt
     7681 accaaaacga ctatctaata tcttttttgt tctttttttc tgcattttct ctgcctttac
     7741 actgattgcc tatagttcaa caaactattt cttattgaag aaagaaaagc agtcagtctt
     7801 tcaagctgta aatattgtta gagttcgtct ttctgaggtg gactctaatt ttacattaga
     7861 gaacttagca gaagttttgt acaaaaacga taaaacacat ctgagaattg atgacagaaa
     7921 gggcagtcga gtcattagga gtgagcgcga tatcacaaat actctagatg cgaatcaaga
     7981 tatttatgtc tataacattg ataaacagat gatttttacc acagataacg aagaatcatc
     8041 tcctggcttg catggtccta tcggtcgtgt gtatcacgac catatcgaag atcagtatcg
     8101 tgggttttcc atgacacaaa aggtatattc taatcggact ggaaaatttg tgggctatgt
     8161 tcaagtcttt catgatttag gcaattatta tgtcattaga gcaagactgc tgttttggct
     8221 actagttgtt gagttatttg gcacaagctt agcctattta atcatcttaa ttactacgcg
     8281 gcgctttttg aagcctttac acaatttaca tgaagtgatg cgtaatatct ctgaaaatcc
     8341 taataattta aacctgcgct cagatatttc gtcaggagat gaaatcgaag aattgtctgt
     8401 tatctttgac aatatgttag acaaattgga gacacatact aagttgcaat cacgttttat
     8461 tagtgatgtc agccatgaat tacgaacacc ggttgcgatt attaaagggc atattggtct
     8521 cttacaacgt tggggtaaag atgacagtga tattcttgaa gaaagcttga cagcaacagc
     8581 gcatgaggct gaccgtatgg caatcatgat taatgatatg ttagacatgg ttcgcgtaca
     8641 aggctcattt gagggacatc aaaatgatat gacagttttg gaagattcta ttgaaactgt
     8701 tgttggtaat tttagagttt taagagaaga ttttatcttt acatggcagt cagaaaatcc
     8761 aaaaacgata gcccgtattt ataaaaatca ttttgagcag gctttgatga ttctgattga
     8821 caatgctgtg aagtattccc gtaaagaaaa gaaaatcgcg attaaccttt cagtgactgg
     8881 caaacaagaa gctattgtta gagttcaaga taaaggcgaa ggaatttcta aagaagatat
     8941 tgaacatatc tttgaacgct tttatagaac ggataaatca cgtaatcgaa caagtaccca
     9001 ggctggatta gggattggct tgtctattct caagcaaatt gtagatgggt atcatttaca
     9061 gatgaaggtt gaaagtgaat taaatgaagg ttcagtgttt atcttacata ttcctttggc
     9121 ccagtctaaa gagagttaga gtagcttaag gcattgttaa tgtgacaggt atagtatgta
     9181 atcattagat aatagtagca gtcttttgcc acaactggtt agaagctgat gctatttttt
     9241 tagcaatgat ggatgacatg aaagaaatac tgtcaatcgc gatgtctttt gttatccttg
     9301 agaatatggt aaaatagtat attagattaa tttgatagaa ttggggtgtt tgcgtgcgtt
     9361 gtccaaaatg taattaccat aaatcgagtg ttgttgacag tagacaagct gaagacggca
     9421 acaccattcg tcgtcgaaga gaatgtgaac agtgtcatac tcgctttact acctttgagc
     9481 gtgttgaaga actcccttta ttagtcatca aaaaagatgg cacacgagag caattttcta
     9541 gagataaaat attaaatggg gttgttcaaa gtgcgcaaaa acgacctgtc tcgagcacag
     9601 atattgaaaa tgtcatttct cgtattgaac aagaagttcg aacaacctac gaaaatgaag
     9661 tgtcaagtac tgctattggt aatttagtga tggatgagtt ggccgaactc gatgaaatca
     9721 catatgtacg ctttgctagt gtctacaaga gtttcaagga cgttgatgaa atcgaagaac
     9781 ttttgcaaca aattacgaat cgcgtacgcg gaaagaaaaa acgtttaaat aatgatgaaa
     9841 ccaattgata cttttacata tctaaaacgc aacaaagtaa ctcttgattc ggtgacttta
     9901 atacagttgt actttccaat tattggaagt gacgcggtct ctatctacca atactttatt
     9961 cacttttttg acgatggttt acaacgtcat aaattcagcg atattttaaa tcacctacag
    10021 tttggtatga aacgttttga agatgctctt gctatattga cagcaatgga attagtgagt
    10081 gtgtatcagc tatcagatac atatcttatt acgttgcacc agccgcttag ccgtgacttg
    10141 ttttttcaac atccagctta ttctcgatta ttagaacaaa agattggaga ggtagctgtc
    10201 tctgagttgc aggtaactgt cccaagtcaa gcaagaaata tttctaagcg attttcggat
    10261 atttttgggg tgcaaggaga tttgacgaac gtacctcaaa agccacaaaa gaattttgac
    10321 ctttcaagtt tccagcaatt aatggttcgt gatgggttac aatttgaaga taatcaaaaa
    10381 gatatcatta gcctttacag tattgctgaa cagtatgata tgacgtggtt tgatacttat
    10441 caaatagcta aggcgacggc tgttaatggg aaaattcgac ctgaacgctt attggctaaa
    10501 aaaaatcaaa gcatgacaaa accaagcaaa gaaaattttt cacaggctga gcaaattatt
    10561 ttgcgagaag caaagcaaga cagtgcttta gtctttttgg aaaaaattaa aaaggctaga
    10621 cgtgcaacga ttactaagga tgaacgcatt ttattgcaaa cattggccaa aatgaatttt
    10681 cttgatgatg ttatcaatgt catggtgctt tataccttta ataagacaaa atctgctaat
    10741 ttacagaaga gttatgtctt aaaaatggcc aatgatttcg cctaccaaaa ggtgtcaacg
    10801 gctgaagaag ctatagtggt tttgcgagcc ttcacggatc gtcaaagtcg tcggcaatca
    10861 aaagtaaaaa caagtcaaag taatgtgcct aagtggagca atcctgatta ccaagagaca
    10921 acaagtcaag aagagcaggc gaaactagat cagttcaaac aggctgcttt gaagaggtta
    10981 gaaaacctag gaaaaggggg tgactagatg gaaaagattg gagaaaccat ggcgaaattg
    11041 ggtcaaaaca ctcgtgttaa tagcgaccag ttgattcaaa ccattttagc ggatcctgaa
    11101 gtagcaagct tcatcagtca acatcactta tctcaagagc aaattaacct tagcttatct
    11161 aagttcaatc aatttttggt ggaacgccag aagtatcaac tcaaagatcc ctcttatatt
    11221 gctaagggct atcagcctat tctagctatg aatgagggct acgctgatgt gtcttatttg
    11281 gaaaccaaag aattggtaga agctcaaaaa caggcagcta tctctgaacg gattcaactg
    11341 gttagtttgc caaaatccta tcgccatatt catttatcag atattgatgt taataatgcg
    11401 agccgtatgg aagccttctc tgctatttta gattttgtgg aacaataccc atcagcagag
    11461 caaaaaggct tgtatttgta cggagatatg ggaattggca agtcttactt gttggctgct
    11521 atggcccatg aattgtctga gaaaaaaggt gtgtcaacga cccttctaca ttttccgagc
    11581 tttgccattg atgtaaaaaa tgccatttca aacggctctg ttaaagaaga aatcgatgcg
    11641 gtcaaaaatg taccggtgct cattttagat gatattggtg cagagcaagc cacttcttgg
    11701 gtccgtgatg aggtgttgca ggtgatttta caataccgta tgttagagga attgccaacc
    11761 ttctttacct ctaattacag ctttgcggat ttggagcgaa aatgggcaac catcaaagga
    11821 agtgacgaaa cttggcaggc caaacgtgtc atggaacgcg tgcgttattt ggctagagag
    11881 tttcatttag aaggggctaa ccgccgttaa gtttgagata gcaatcaaga agaatagcta
    11941 cacgtatgag tgagtgaaag aaaaggagaa tcatggtttt acctaccgtt gccattgtgg
    12001 gccgtccaaa tgtgggcaag tccaccttat ttaatcgaat cgcaggagag cgcatttcaa
    12061 ttgtagaaga cgttgaaggg gttactcgtg accgtattta tgctactggg gagtggctta
    12121 accgccaatt ctcattgatt gatacaggtg gtattgatga cgttgatgcc ccgtttatgg
    12181 agcaaatcaa gcaccaggct caaattgcca tggaagaagc tgatgttatc gtttttgttg
    12241 tttctggtaa agaaggggtg accgacgctg acgaatatgt gtctaaaatt ctgtatcgaa
    12301 ccaatacccc agtcatttta gctgttaata aggttgataa tcctgaaatg cgtaatgaca
    12361 tttatgattt ttattcactt ggtttgggtg atccttatcc agtttcttct gttcatggta
    12421 tcggaacagg ggatgtctta gatgcgatcg ttgaaaactt gccagtagaa gaggctgaag
    12481 aaaatgatga tattattcgc ttcagtttaa tcggtcgtcc taatgttggg aaatctagct
    12541 tgattaacgc tattttaggt gaggaccgtg ttatcgctag ccctgtcgca gggacaacac
    12601 gtgatgccat tgacacgcat tttacggatg ctgacggtca agaatttacc atgattgaca
    12661 cggctggaat gcgcaaatct ggcaagattt acgaaaatac agagaaatat tctgtcatgc
    12721 gtgccatgcg tgccattgac cgctccgatg tggtcttgat ggttatcaat gctgaagaag
    12781 gtatccgtga atacgacaag cgtatcgctg gctttgcaca cgaagctggt aaaggaatga
    12841 ttatcgtggt taacaaatgg gataccattg acaaggataa tcataccgtt gctaagtggg
    12901 aagccgatat tcgtgaccaa ttccaatttt tgacatacgc tccgattatt tttgtgtcag
    12961 ctttgacgaa gcagcgcctc aacaaattgc ctgacttgat taaacgtatc agtgagagtc
    13021 agaataaacg tatcccatct gctgtcctca atgatgttat catggatgct attgccatta
    13081 atccaacgcc aacggataag ggtaaacgtt tgaaaatttt ctatgccact caagtgtcag
    13141 taaagccacc aacatttgtc gtctttgtta acgaggaaga attgatgcac ttctcttatc
    13201 tacgcttctt ggaaaaccag attcgcgcag cctttacctt tgaagggaca ccgattcatc
    13261 taattgctcg caaacgaaaa taagaaatga acatcaacta aaatgctgac ctaagaaata
    13321 atctcatcat tgataaggac tgtgttgtgt atgttacagg agacagtcct ttttataata
    13381 cctttaaggg tgtagacgga agattagtag caaacaaaga aaaaggattt tgacaagaaa
    13441 tatcagtcgg tttttgctat aatgaaagga taagcaaaaa ggtggaaaaa tgatggctag
    13501 attaattcca ggacgagtaa ggaatgaagg tattaagctt tatgagcaag gtttagtttc
    13561 attccaagat gataataaag gcattcttca aatagaagtg gagacttatc aggttcaata
    13621 tggagcagat gatgaggata tcacttgtca atgcgacaca tttcatatga aacattattg
    13681 caagcatatt gcagcagtcg agtatttttt aaaaaatgat caaaaaggta agcttttttt
    13741 aaaacagtta acaaatcaaa caaaaatcaa agaaacaaca aagaaaatga catcttttgg
    13801 tagcctcttt ttagatagct tagccatgaa tgaagatgat tctgttaaat acaggctgtc
    13861 tgctcttggt agtcgaagcc ctttttcgtc agattactgg tggagtctga aaatcaatcg
    13921 tttaccagat gatcgttctt atgtgattcg ggatattaaa ggctttttgc agcttattaa
    13981 aaaagaaggc ttttatcaga ttggaaaaaa ttattttgaa caactttcat ggctgcagtt
    14041 tgacccatct agtcaggccc ttattgagtt tttatggcgc ttagcatctg atactgacaa
    14101 aggggacaac gagaacattt ttccaaatca tgcaaggcat ttgcgcttac ctagtggttt
    14161 ttttgaagaa ggtattcact atttgacgtc actttatgac tttacttttg aggggccttc
    14221 tcaaacttat catcatcttt ttgtccgttc tttggaagca gaggcaggcc tttatgagtt
    14281 taaagtggaa gtgcatcgca aatctattga attgcaaatt gctgaaaaaa atgtgcaata
    14341 cctctttgat aatgactatc ttctttatca agataccttt tatcacttga cgttaaagca
    14401 acgaaaaatg gttcaggcta ttcgtagtct gcccattgag gccgacttgg ctaaacatat
    14461 tcattttgat ttggatgatc atgcgaaatt agctgcaagc ttatcagatt ttaaacagat
    14521 cggtctagta gaggctccta aaagctttgc tattagagac tttgaggtga cttttcaatt
    14581 tgatttgtta aatcgagatg aaatcagttg tcagcttatg tttgattatg gcaattacca
    14641 agttagtgac aaagcaagtt tagaagcact tccttttgct agtcatttaa aaaaagaaga
    14701 aaaaatcaat cgttctttac ttgcttttgg cttctcgcca caattttact caaaaaagcg
    14761 actaacaagt gcaaaagagc tctatacttt ttttgaagaa acagttccat gttttgagcg
    14821 cttaggtaat gttgcgttga gtacagctat ccaagcatta caagtgaaag aaatgcccaa
    14881 gatcgctatt agacgcaatc agggattact agatatttcg tttgattttt caaccattat
    14941 tgaaaatgat attgaccaag ctgttacagc tctttttcaa aataatcctt attttgtgag
    15001 tcaaacgggt caattagtgg tttttgatga tgaaactcaa aaagttagca aaagtttaca
    15061 agaattaaga gcaagacagc taaaaaatgg tcacttgcaa ctggatggca ttagagctct
    15121 acaagtatcc aaactttttg aaggcatgac atctgttcat ttttcaaagg aattagaaga
    15181 gttagcctat catttgcagc atcctgaaac tttttcaata aaaccgttac cagttaaggc
    15241 tcaaatgcga gattatcaac gcaacggtgt tcagtggtta tcaatgctca atcattatgg
    15301 ctttggtggc attttagcag atgacatggg acttggaaaa actctccaga cacttgcttt
    15361 tttagctagt cacctgaaat cagatagtaa agtgctcatt ttatctccat ctagtcttat
    15421 ctataattgg tttgatgaat gtcaaaaatt cacacctcag ctagatgttg tggtttctta
    15481 cggacttaaa caaatcagag atcaaatcat cgaagaaggt catcaaataa ccataaccag
    15541 ctattcctcc tttagacagg attttgagac ctatcaagcg tttcactacg attatcttat
    15601 cttagatgaa gctcaagtga taaaaaatgc acaaactaag atttcacact gtttacgtgc
    15661 gtttaataca gccaattgtt ttgcgctttc gggcactcct attgaaaata aaatgcttga
    15721 aatttggtcc attttccaaa ttgttttgcc agggttgcta ccgactaaaa aagagttttt
    15781 aaaattaaca gctgagcaag tatcacgcta tatcaaaccc tttgtgatgc gtcgtaaaaa
    15841 agaagatgtc ctaccagaat tacctgattt aattgaaact aattattcaa acgagatgac
    15901 agatgaacaa aaagctattt acttagcgca gttaaggcag atgcaagatc aaattcgaaa
    15961 ttctagtgat gtggatatta gccgtcaaaa aattgagatt ttatctggta tcactcgatt
    16021 gaggcaaatc tgtgacactc caagtctctt tatggattac caaggcaaaa gtggtaaact
    16081 agatagtttg cgaatcttat tgacacaaat taaagaaaat ggtcatcggg ctttgatttt
    16141 ttctcaattt agagggatgc tggacttggc caagcaagag atgactgctc tagggttgac
    16201 ctcttatcaa atgacgggat ctacccctgc caatgaacgt caagaaatga ctagagcctt
    16261 taataacggt tccaaggatg cttttttgat ttccctcaag gcaggtggag ttggaatcaa
    16321 ccttacggga gcagacacag tgattttaat cgatttatgg tggaatcctg ctgttgaaat
    16381 gcaggcaatc agtcgcgcct accgtattgg tcaaaaagaa aacgttgaag tatatcgctt
    16441 aatcactcga gggacgattg aagaaaagat tttagagctt caagaaagta agcgcaattt
    16501 ggtgactaca gttttggatg gcaatgaaag ccgagcaagt atgtccattg aagaaataaa
    16561 agaaattttg gggctaaaca ctcattaatc ttccttgatt ttagtgacat taaaaaccct
    16621 ttaaagaaga tgacaccaaa agcaccttat ataacctcgt taaaacgctt ctttttgaaa
    16681 tatctttatt gatatagcga ttgtcatttg ctagtaatga ttaaaacatt tagaaaaaga
    16741 cacgtcatag aatcatcaag gaatgctttg aaaaataaca gtatttaagt tataatagag
    16801 gatgctacaa gaagggagaa tcaaaaaagg atggtaaaaa atcagtttcc tttagttgca
    16861 gatggcattg ctattagtga tccagcaaag caaatggctc tgtatgaaaa tgaagatctc
    16921 attaccaaca tccgtggcta ttaccaggac aaggagtatg atgatattgc tagaaatgag
    16981 gagtttactg ctaaagcaac ttctcggcag accccttcta gtaagcgctt ttgtagcaat
    17041 gatgaaaaac accattatgt caaagaggcg cgtcaaaaag caaagcaaga tctcaaggaa
    17101 aaaagacagg cttatcttgc caaagaaatg gcctatgttc ctaaacaggt ttctaaaaag
    17161 caacagcctg cggattcttc tccttctcaa aagcaagcaa caacagaaat gagtcgtttt
    17221 acaaaaaagc ttcatcaaga caactatatt ttagctgagt tgccaaaaga atataaagag
    17281 ccaaaaaatc ttcctcaaca aggaactaca aaaaaaaata attacgattt tttaaaatcc
    17341 agtcaaattt acaataataa agaaatgaga caacaacgag aaaaaacaat tgcgcaagag
    17401 cttaatctta gtaggtttga ggatcttcct taataaatct actcagcgta tgcagatgac
    17461 aaaggagtta agatgtcaaa aacgtatcat tttatcggaa ttaaagggtc aggaatgagt
    17521 gccttggccc ttatgttgca tcaaatgggg cataaggtgc aaggtagtga tgttgaaaaa
    17581 tactatttca ctcaaagagg attggaacaa gcgggcatca ctatcttacc ttttagcgag
    17641 gacaacatta cgccagatat ggaacttatc gttgggaatg cctttcgtga aaacaacaaa
    17701 gaagtggcct atgctttgag acaccagatt cctttcaaac gttatcatga ctttttaggt
    17761 gattttatga aatcatttat cagttttgca gtagcaggtg ctcatggtaa aacttctaca
    17821 acgggtttat tgtcacatgt cttgaaaaat atcacagaca catcttattt aattggtgat
    17881 ggtactgggc gtggatctgc taatgcacag tattttgttt ttgaatcaga cgaatacgaa
    17941 cgccatttta tgccttatca cccagaatac tctatcatta ctaatattga ttttgaccat
    18001 cctgattatt tcacaggaat tgctgatgtg cgaaacgctt tcaacgatta tgctaagcag
    18061 gtcaagaaag ctttgtttgt ttatggtgaa gatgacgaac taaaaaagat cgaagcacct
    18121 gcacctattt actattatgg ttttgaagag ggcaatgatt ttatcgctta cgacattacg
    18181 cgtactacga acggatcgga ctttaaggta aaacaccaag gagaggtcat tggtcagttt
    18241 cacgtacctg cttatggaaa acataacatt ttaaacgcta cagcagtaat tgcaaacttg
    18301 tttgtagccg gcattgatat ggctctagtg gcagaccatc ttaaaacttt ttcaggtgtg
    18361 aaacgtcgtt ttacagagaa aattatcaat gacactatta ttattgatga ctttgctcat
    18421 catccaaccg aaattgtggc aacaattgat gcggctagac aaaaataccc aagtaaagaa
    18481 attgtagcaa tattccagcc acatactttt actcgcacta ttgccttatt agaggatttt
    18541 gcttgtgctt taaatgaagc tgacagtgtt tatttagccc agatttatgg ttctgcacgt
    18601 gaagtagata aaggtgaagt taaggttgaa gatttggctg ctaagattat caaaccatca
    18661 caagtagtaa cggtggaaaa tgtctctcct cttcttgatc acgataatgc tgtttatgtt
    18721 tttatgggag ctggagatat tcagctatat gaacattctt ttgaggaatt acttgcaaat
    18781 ttaactaaaa ataaccaata acatgtcctg ccttaggcag gttttctcat tctaaaggag
    18841 tttgatatgt tgattagaca ggttcaagga tccgatttgg aagttattgc taccattgaa
    18901 agtgacaatt tttcaccaca agaagcaacg acaagagcag ttcttgaaga gcacatacgg
    18961 ctgataccag atactttttt agtggcactt atcgatcagg aaattgttgg ctatatcgaa
    19021 ggtccagttg tcactactcc tattttggag gattctttgt tccacggggt gactaaaaat
    19081 cctaaaactg gaggctatat tgctattact agtttgtcca tagctaaaca ttttcagcaa
    19141 caaggggttg ggacagcttt gttggcggca ctaaaagatt tagtagtagc gcagcaaaga
    19201 acaggtctta ttttgacttg tcatgattac ttgatttcct attatgaaat gaatgggttt
    19261 attaaccaag gaatttcaga gtctcaacat ggtggaaccc tttggtacca aatgatttgg
    19321 aaactttaga atcacagctg attcaactgt tggtttgtta aaaataagta acaaatgcat
    19381 catttaattg caattaggat acttttaagt tataatggcg gttgattata tttaggagga
    19441 ttggctttga ccgattttaa ggataaagac caacaagatc agcagcgaag ctttaaagag
    19501 cagattcttg ctgagttgga aaaagcaaat caaatcagaa aagaaaaaga ggaagaactt
    19561 tttcaaaaag agttggaagc taaagaagca gctaggagaa cggcccagct atatgctgaa
    19621 tataaaagac aagatgcttt tcaaaaagag tctatagcac ataacaataa gacagctaaa
    19681 cactttcaag ctataaaagg tgcggtaatg acttcagaag cgcttaaacc gactttactt
    19741 tctgaaaaag aaaactcatc tttaaaaacg acaaataaga gagtcgtgca ggcaaatgag
    19801 cttcaagaga ctgcctctaa agaatctcaa gtaccgttaa ctattgagaa aggtcattca
    19861 gtgagacgaa aattaagcaa acgccaacag actgagcgag ctgctaaaaa gatttcaacc
    19921 gttttgatta gttctattat tataaccctt ttggctgtta ctctagcagg agcaggctat
    19981 gtttatagtg ctttaaatcc tgttgataaa aatagtgatg cctttgttca agttgagatt
    20041 ccatctgggt caggcaataa attgattggt caaattcttc aaaaaaaagg tttaatcaag
    20101 aatagcactg tttttagttt ttatacaaaa tttaaaaact ttacaaattt tcagagcggg
    20161 tattataatc tgcaaaaaag tatgagtcta gaagaaattg ctagtgcttt acaagaaggt
    20221 ggtacagcag aacctaccaa gccatctctt gggaagatct tgattccaga aggatacacg
    20281 attaaacaaa tagctaaagc tgttgagcat aatagcaagg gaaagaccaa aaaagctaaa
    20341 acacctttta acgagaagga ttttttggat ttagtcacgg atgaggcttt tattcaagat
    20401 atggtaaaaa gatatccaaa attattagca actatcccaa ctaaagaaaa agctatttac
    20461 cgtttggaag gttacctttt cccagcaacc tataactatt acaaagaaac taccatgaga
    20521 gaacttgtag aggacatgct ggcagctatg gatgctactt tggtacccta ttatgataaa
    20581 attgctgcta gtggtaagac agtcaacgag gtattgacct tggcctcttt ggttgaaaaa
    20641 gaaggttcaa cagacgatga cagacgtcaa attgcaagtg tcttttataa ccgccttaat
    20701 agcggaatgg cactacaatc taatatagct attttgtatg cgatggggaa acttggtgag
    20761 aaaacaacct tggctgagga tgctactatt gacaccacca ttaattctcc ttataatatt
    20821 tataccaata caggtctgat gcctggtcca gttgctagct cgggggtttc tgcaattgaa
    20881 gcaaccctaa atccagcctc aacggattat ttatactttg tggccaatgt ccatactggt
    20941 gaagtttact atgcaaaaac atttgaagaa cactctgcaa atgttgaaaa atatgtgaat
    21001 agtcaaattc agtaaacaca aacatggtgc ttaagcacca tgtttgtgtt tctgattcgt
    21061 tcaaaaaaga aaagagagaa aacaattatg gcagaaaaaa cgtatccgat gaccctaacg
    21121 gaaaaagaac aacttgaaaa agaacttgaa gaattaaaac ttgtgcgtcg tccagaaata
    21181 gtggagcgta ttaaaattgc acgttcgtat ggagatcttt cagagaactc tgaatacgat
    21241 gccgcaaaag atgagcaagc ttttgttgaa ggtcaaattt caacgcttga aactaagatt
    21301 cgctatgctg aaatcattga cagtgatgct gttgcaaaag atgaagtcgc tatcggaaaa
    21361 acagttatcg ttcaagaagt tggaacaaca gataaagata cttatcatat tgtaggtgct
    21421 gctggagcag atatcttctc cggaaaaatt tcaaatgaaa gcccgattgc tcaagctttg
    21481 attggtaaaa aaacaggtga caaggttaga attgaatcac cagcagctac ttatgatgtt
    21541 gaaatcatca gcgttgaaaa gacaaattaa tccgatgaag ccattatttg cctaaccact
    21601 aagtgttttg gttgctaatg gcttttctag tatcttcaaa tgaggttgac tgttaggaag
    21661 gtcaagtatt aatcgcattg attatgagtc aagaggacta tagatcaaag atcgttttcg
    21721 atggttattt aataccaaaa gaaaagacca gcaccttaat gtactgaccc caaaaagttg
    21781 gacactatat tttaagtata ggaagtgtat aatctaagga aactgacact aatgattgac
    21841 cgttttgcaa gactttatta atgatttctt gctttatttt aaatgaataa gtctgatatg
    21901 tttccttcct taacactatc gactccataa tgacccatca gtcaaacggt atatctcaaa
    21961 cgactacggt ttactccaaa ttcattggct agttgaggcc aagaaacacc tgatttttta
    22021 atgctaaatt tctagcttat cttcatagct taatttcata caaaaaaacc ccaatcgtta
    22081 gatttttttg atatgtcccc tttcactaga tgagtccagt aaaagggggc atatcgtttt
    22141 ttgtctaact tttggagtgc agttcataat tgtgctaggt tttttgtctt tcttaacgct
    22201 ttcgctgttt tccagcatta cgattggatt ttattttttt aggcaagtta gcctgttcca
    22261 tgttttgtga aggcgtaacg tccttacgag aagaagttga ttggtatgct ttaggcgggt
    22321 ttttagcgta ttcttcttta atttgcttat gcaatcgagg ttttaagagg taggttgtga
    22381 ttaactgttg aataatacta aagaaaccac caactagcca gtaaagacca acaccagcag
    22441 ggagtgagaa ggacatgaag atcatcatga taggcatggt gtacatcatc gtcttcattt
    22501 gctcacgttg ttcttctgaa acggccatca ttgataacca tgattggaag aagtaaagag
    22561 cagcgataat tgctgttaac actaaactac ggctaccaag atcaataccc ataaaggtgc
    22621 ttgttgatac tcctttagtg tattgagcgg caaaatacat ggcagaaaag aatggcatct
    22681 ggatgagaag aggtagacat ccaatacctc caagagggtt aatcccatga gcacgctgag
    22741 cagccattaa ttctgtttgg gcagccattt tttcttcctg actatttgcc tgtttgatac
    22801 gtttgttgat tggttcaaaa acaggtttca agaaggccat tttctcagat tgataacttg
    22861 ctttccaaga ttgatataga cctagtggta agataagtgt tctaacaata atggttacga
    22921 tgatgatagc cagtccataa cctagtccag cattgtttgc aaagtaatcg ataaagtatg
    22981 acatgggttt tccaagaaat tcccaaatca tacctttggg atttccgtga gcgtctcttc
    23041 ccacacagcc tgtcaaggtg agtagaattg acagtgctag tcctgaaaag aggatgcgat
    23101 ttaatgttag tttcaatgtg tttatccttt aattttaata tacttatcta ttttacagtt
    23161 tttttcagaa attcacaata gttctgaagg ccgattttta cttgcctatt tgaaagtcct
    23221 gaaagtcttc aaaattagcc atggtgacat ccacataagt gacttttgcc catttggatg
    23281 gtcctttacg aacttcttga ataaatgtgg ctattttatc tgaatctttt gattgggcca
    23341 gaatttcaac ggtcccatcg ttgttattcc agacacgacc ataaatatct cctatatcta
    23401 gagctaaagt atgggtagcg tatcgaaaac caacaccttg tacacgtcca gaaacaatta
    23461 aacgtacttt ttgcataaga agggcctcct tgcttttatt atagcacata cttagcagga
    23521 aatctcttta gctaattgtc
//
LOCUS       DAUGQX010000030        22562 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUGQX010000030 DAUGQX010000000
VERSION     DAUGQX010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22562
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.030"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..270)
                     /gene="cadX"
                     /locus_tag="VIA51_001164"
     CDS             complement(<1..270)
                     /gene="cadX"
                     /locus_tag="VIA51_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEQ8683108.1"
                     /translation="MKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRR"
     gene            complement(282..896)
                     /locus_tag="VIA51_001165"
     CDS             complement(282..896)
                     /locus_tag="VIA51_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEQ8683109.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLSK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFIAVVYLGLGMYILIENNSFDMLWAVLG"
     gene            complement(1189..1338)
                     /gene="rpmG"
                     /locus_tag="VIA51_001166"
     CDS             complement(1189..1338)
                     /gene="rpmG"
                     /locus_tag="VIA51_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8683110.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(1354..1536)
                     /gene="rpmF"
                     /locus_tag="VIA51_001167"
     CDS             complement(1354..1536)
                     /gene="rpmF"
                     /locus_tag="VIA51_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEQ8683111.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            1756..3036
                     /locus_tag="VIA51_001168"
     CDS             1756..3036
                     /locus_tag="VIA51_001168"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEQ8683112.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYSHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDIYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            3374..5122
                     /gene="aspS"
                     /locus_tag="VIA51_001169"
     CDS             3374..5122
                     /gene="aspS"
                     /locus_tag="VIA51_001169"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEQ8683113.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSNVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGNDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            5115..6056
                     /locus_tag="VIA51_001170"
     CDS             5115..6056
                     /locus_tag="VIA51_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8683114.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            6076..6954
                     /locus_tag="VIA51_001171"
     CDS             6076..6954
                     /locus_tag="VIA51_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8683115.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            6997..7869
                     /locus_tag="VIA51_001172"
     CDS             6997..7869
                     /locus_tag="VIA51_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8683116.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(7896..8204)
                     /locus_tag="VIA51_001173"
     CDS             complement(7896..8204)
                     /locus_tag="VIA51_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8683117.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(8292..9983)
                     /locus_tag="VIA51_001174"
     CDS             complement(8292..9983)
                     /locus_tag="VIA51_001174"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEQ8683118.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLTDAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            10274..10711
                     /gene="argR"
                     /locus_tag="VIA51_001175"
     CDS             10274..10711
                     /gene="argR"
                     /locus_tag="VIA51_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8683119.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            10708..11060
                     /locus_tag="VIA51_001176"
                     /pseudo
     CDS             10708..11060
                     /locus_tag="VIA51_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623648.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            11047..13602
                     /gene="mutS"
                     /locus_tag="VIA51_001177"
     CDS             11047..13602
                     /gene="mutS"
                     /locus_tag="VIA51_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEQ8683120.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTNLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPS
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEVIDVMNMTPLQAMTTLYELKKLL"
     gene            13731..15713
                     /gene="mutL"
                     /locus_tag="VIA51_001178"
     CDS             13731..15713
                     /gene="mutL"
                     /locus_tag="VIA51_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEQ8683121.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKVELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLE
                     NEGQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            15724..16944
                     /locus_tag="VIA51_001179"
     CDS             15724..16944
                     /locus_tag="VIA51_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8683122.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYCFDETRPETHAFDHGKGLLASFQNYRQVFHDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLSFTFTQFYAIWLSVVLLTFGEMINVS
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFAVIALL
                     GIYFTVVSAKMKKV"
     gene            16946..17542
                     /gene="ruvA"
                     /locus_tag="VIA51_001180"
     CDS             16946..17542
                     /gene="ruvA"
                     /locus_tag="VIA51_001180"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEQ8683123.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
                     LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            17552..18112
                     /locus_tag="VIA51_001181"
     CDS             17552..18112
                     /locus_tag="VIA51_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEQ8683124.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLDDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVATFTSEEMADALENPSIIRHKLKLAATVNNAIA
                     VQKIQKEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            18181..19452
                     /locus_tag="VIA51_001182"
     CDS             18181..19452
                     /locus_tag="VIA51_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEQ8683125.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            19541..20677
                     /gene="recA"
                     /locus_tag="VIA51_001183"
     CDS             19541..20677
                     /gene="recA"
                     /locus_tag="VIA51_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEQ8683126.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDLKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            20968..21366
                     /gene="spx"
                     /locus_tag="VIA51_001184"
     CDS             20968..21366
                     /gene="spx"
                     /locus_tag="VIA51_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEQ8683127.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            21479..21748
                     /locus_tag="VIA51_001185"
     CDS             21479..21748
                     /locus_tag="VIA51_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEQ8683128.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            21745..22164
                     /gene="ruvX"
                     /locus_tag="VIA51_001186"
     CDS             21745..22164
                     /gene="ruvX"
                     /locus_tag="VIA51_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEQ8683129.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AKRMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            22176..22481
                     /locus_tag="VIA51_001187"
     CDS             22176..22481
                     /locus_tag="VIA51_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEQ8683130.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
BASE COUNT         6818 a         3836 c         4906 g         7002 t
ORIGIN      
        1 tcttctagtg tccaagatgt tttgattggc tagtttacga agatggtggg aggcagatgc
       61 catactgaga tttaataaac aggctatatc gcagacacag agttcttcga cggcaaggag
      121 ataaaagatg atatttatct gtttattatc ggtaaatttt gataaaatac gaagtgattt
      181 ttggactttt tccttttcaa ggtagttcgt tgcggttgta acattttgtt gatttataac
      241 acccacttga cagatactat cttttttcat aattttttct cctagcctaa cacagcccat
      301 agcatgtcaa agctgttgtt ttcaatcagg atatacatcc ccaatcctaa ataaacaacg
      361 gcaataaacc atctgctata tttttccaaa gtttctccaa cagaagggac ttgtgccaat
      421 ttttgggcag aaaaaaccaa gagataaatc atgactagaa aggtaagtaa agccactatc
      481 aaattcgcta aatttaaggt agtaaaatat gggacaaaga caccaatatt gtcagcacca
      541 caacttgcaa aagtaatcat agcgactaga aaaatcaggt ttttattatc tttgctcaaa
      601 ccttctttgg caatagcttc tccatcagaa tctcctaaaa gcaaaacttt gaggcctagg
      661 aaaattggaa tcaaaccgag caaacctaaa atctctttac taggaatata atctaagaca
      721 aatgcaaaaa gcaaacttag caatattaga ctaacagagc ctagaaattg tcctaaatag
      781 atgttaatga tgtcttttct gctttttctt ttggcaaaaa ataacattag gataataagt
      841 aagtctacgg ctgtcccaga atacaggatt attgaagtaa caacattttg aatcataaaa
      901 cacctcattc aaatatattt ttgaatgaat tttaacatta aactttgtag atgtcaattt
      961 cagctacacc aaaatataga taagaagtta gtgtaccaaa tataaaaaag ccctgccatc
     1021 caaatgataa cagggcttaa cttcaatatc caaatgatat attcatctaa aaaaggtaga
     1081 gtaaaaggta gagttcttat tgatttatat tacaatgtaa tgaacttcaa aaattcaaaa
     1141 atcgcttaaa atcaatgttt tgacgtctaa tgacgtgtag tgaacccctt acttaacctc
     1201 tgtaaatgta acgtgtttac gtaattttgg tgagtatttt ttcaattgaa gacggtctgg
     1261 agtgttacgt ttgttttttg aagtaaggta caagcgttca ccagattctt tatgttcaag
     1321 tgtaatattt acgcgcatgg tatctccctt ctattattta gcttcgttag ctttagcgat
     1381 tttacgtcct ttgtagtatc ctttaaggga tacacggtga gaacgtgagt aatctccagt
     1441 agtttcgtcg aattgtacag atggagctgt caatttgtag tgtgtacgac gtttgttttt
     1501 cttcgctttt gacgtgtgac gtgcaggtac tgccattttc ttgttcttcc tttcgatgtg
     1561 taagttttga ttttcatcaa cttcactatg ataacatatc ttttttgtaa agtaaagtta
     1621 cttgacaaaa ctttttattt ttacaatttc atggtgaaaa tactatcaaa ctaaagcaaa
     1681 tgatatatgc ttgtttaaaa tataagaaaa aatggtagaa tgtttaaaga gaaaactaat
     1741 caaagaggta aacttatgaa acttcaaaaa ccaaaaggaa cccaggatat tctgcctggg
     1801 gatgctgcga aatggcagta tgtggaatct gttgcgcgtg atacgtttag ccaatataat
     1861 tatggagaaa ttcgtactcc tatgtttgaa cactacgagg taatctcgcg gtctgtaggt
     1921 gatacgactg atattgtgac gaaggaaatg tatgatttct atgataaagg agatcgtcac
     1981 attaccttgc gaccagaggg tacagctcca gtggtgcgtt cttatgttga aaataaattg
     2041 tttgcgccag aggtccaaaa acccgtcaaa ctttattata tcggttccat gttccgctac
     2101 gaacgtcctc aagctggtcg tttacgtgaa tttcaccaga ttggggtaga atgtttcggc
     2161 gctgctaatc cagcaacaga tgttgaaacc attgcgatgg cctatcacct ctttgaaaaa
     2221 ttgggcatta aggatgtcac ccttcattta aatagtttgg ggagtcctga gagtcgtgca
     2281 gcttatcgtc aagccttgat tgactactta acaccaatgc gtgatcaatt atctaaagat
     2341 agtcaacgtc gcttggatga aaacccactg cgcgtgcttg attctaaaga aaaagaagat
     2401 aaactagccg ttgaaaaagc gccttctatt ttggattact tagatgagga aagtcaggcg
     2461 cactttgagg cggtcaaaga tatgcttgaa gcacttgaca ttccttatgt gattgacacc
     2521 aatatggtgc gtggccttga ttactatagc cacactattt ttgaattcat cacgtctgtg
     2581 gaaggttctg acttaactat ctgtgcgggt ggacgttatg atagtttggt aggttatttt
     2641 ggtgggcctg agactccagg atttggcttt ggtcttggtt tagaacgtct cttgatgatt
     2701 attgaaaagc agggcattac cttgccaatt gagacagaga tggatattta ccttgctgtg
     2761 ttaggtgatg gtgctaatag caaagcttta gaattggttc aagccattcg ccgtcaaggg
     2821 tttacagctg aacgagatta ccttggccgt aagattaagg ctcagtttaa atcagccgat
     2881 acctttaaag caaaattggt aatgacttta ggagaaagtg aagttgaagc aggcaaagct
     2941 gtgattaaga ataatcgtag tcgtcaagaa gtggaagtca gttttgaaga tatgatgaca
     3001 aactttgcga acatctcaga gcaattatta tcttaatgat tttattgtcg tcataagctt
     3061 gtgttgatat gattgtttag aagataatca ctaaaacagg tgtaacttct ctttttagaa
     3121 gggagttgca cctgtttgtt ttctgtaagg ggattgatta gctttcttag tattctgtga
     3181 ggacacttga tatgtcaaaa tactgacggc tcagtatttt tgctttatct ttagaaaaac
     3241 tctttttaaa tgggtggggt ttttaagggc tttttgctat aatagtaggg aatgaattaa
     3301 ttgatttata tagtgaaagg aattggaaac gagcaggttt cacaggattc tgtttgtttt
     3361 agggaattta tttatgaaac gtagcatgta tgcagggcgt gttcgcgaag aacacattgg
     3421 aacgacaatc acattgaaag gatgggtcag tcgtcgtcgt gacttgggtg gtctcatctt
     3481 tattgatttg cgtgaccgtg agggtgtgat gcaattagtc attaaccctg aggaagtttc
     3541 cagtaatgtg atggcaactg ctgaacgctt acgtagtgaa tatgtgattg aagtggaagg
     3601 ttttgttgaa gctcgacaac aagccaatga taagttggcg acaggaatgg ttgagttaaa
     3661 agtatctgct ttgaccattt taaacacagc taaaacgacg ccttttgaaa ttaaagatga
     3721 cgttgaagta agtgatgaca cgcgtttacg ttaccgttac ttagatttac gacgtccaga
     3781 aatgttagaa aacttcaagc tacgtgcaaa agtgactcat tctatccgta attaccttga
     3841 tgaccttgag tttatcgatg tcgagacacc tatgttgaca aaatcaactc cagaaggtgc
     3901 gcgtgactat ctggtaccaa gtcgtgttag ccaagggcat ttctatgctt tgccacaaag
     3961 tccgcaaata accaaacagt tattgatgaa tgctggcttt gatcgctatt atcaaattgt
     4021 gaaatgtttc cgcgatgaag atctacgtgg tgaccgtcaa cctgagttta cacaagttga
     4081 cttggaaacg tcattccttt ctgaacaaga aattcaagac atcgttgaag gcatgattgc
     4141 taaagtgatg aaagagacaa aagaaataga tgtaacccta ccattcccac gtatgagcta
     4201 cgatgtagca atgaatagct acggctctga taaaccagac acacgttttg aaatgctttt
     4261 acaagacttg acagtaactg tcaaaggaaa tgacttcaag gttttctcag aagcaccagc
     4321 tgtcaaggcg attgtggtga agggaaatgc agatcgatac tctcgtaaag atattgacaa
     4381 attaactgag tttgccaaac aatttggtgc taaaggcctt gcctgggtta aggtgacaga
     4441 tggtcaattg gcaggcccag tagccaagtt cttgacagct attgagacag agttgtcaag
     4501 ccaattaaaa cttgctgaga atgatttggt tttatttgta gcggatactc ttgaggttgc
     4561 taataataca ttaggtgccc ttcgtaatcg tattgccaag gaccttgaca tgattgatca
     4621 gtcgcagttt aatttccttt gggtggttga ttggccaatg tttgagtggt cagaagaaga
     4681 aggacgttat atgtcagctc atcacccctt cactcttcca acgccagaat ctgctcatga
     4741 gttagagggt gatttggcta aggtacgggc tattgcttac gacatcgttt taaatggtta
     4801 cgagcttggt ggtggtagcc tgcgtatcaa tcaaaaagag atgcaagagc gcatgttcaa
     4861 ggctcttggc tttaccgctg atgaagctaa cgaccaattt ggtttcttac tagaagcgat
     4921 ggactacggc tttcctcctc atggtggctt ggcaattggt cttgaccgtt ttgtcatgtt
     4981 gcttgctgga aaagacaata ttcgagaagt tattgccttc cctaaaaata acaaagcctc
     5041 tgatccaatg acgcaagcac ctagtcttgt ttctgaaaac caattagaag aactcagtct
     5101 tcaaatagaa agtcatgatt aagaaaacaa cctataagaa aaaagttaaa tatgtcatta
     5161 gtagaggggc caagaaagtt ggcctactcc acgctctaag aagtatttca agagaaaaat
     5221 atgcagagaa gatttcggct tctctgcttt atggcattct ctctagtatt gctgtgaatt
     5281 ttttcttcca gcctgggcat gtttattcaa gtggagcaac tggtctagca caggtttttt
     5341 cagctcttag tcatcgtctt ttaggctatg attttcccat cgcctttgcg ttttatttga
     5401 ttaatattcc tttgcttatt ttagcttggt ataaaattgg gcatcaattt accattttta
     5461 cctttatcac agtcagcatg agttctttct ttattcaaat catgcctcaa gtgacgctga
     5521 cgactgatcc tcttatcaat gctatttttg gtggtttggt tatgggaatg ggaattggta
     5581 caggtctcaa atcacgtatc tctagtgggg ggactgatat tgtcagtttg acccttagaa
     5641 aacgaacagg caaggatgtg ggcagtctct cattgatggt taatggtgca attttagcct
     5701 ttgcagggat tttatttggc tggcagtacg ccctttattc tatggtctct atctttgtat
     5761 caagtcgtgt tacggatgcc attttcacca agcaaaagaa aatgcaggca actattgtta
     5821 ccagccatcc agagcgtgtg attcatatga tccataaacg tctgcatcgc ggagtgacca
     5881 gtatcaacga cgcagaaggg acttacaagc atgaacaaaa agcagttttg attaccattt
     5941 tgacatgtga agaataccca gaattcaaat ggctgatgtt aaaaacagac ccacaagcct
     6001 ttgtttcagt ggctgagaat gttagaatta tcggtcgttt tgtggaagat gattaagaaa
     6061 aacacaggag gtgtcatgtc aattgaccaa cgtttacagt taaagaaatt ttgctttatt
     6121 attttaggag ctgctatcta cgcctttgct tttgtttatt tttacatggc taatcgcatt
     6181 gcagccaatg gtttagctgg tctcacccta gttggtaagg cactttttga gattgatcct
     6241 tctttgatag gctatttgat taatttgcct ttggtcttgc tgggagctag atgttttggg
     6301 aaaagagcca tggtttacac agtaacgggt attttatcac tttacttttt tgtgtggctg
     6361 tttcaacgct ttcctttggt cgttgacttg gaccatgaca atttagtcgt ttccttgatg
     6421 gctggaatta ttggtggtct aggtggcggt cttgtgtttc gcaatggtgg aaccatcggt
     6481 ggagcagata ttattgctaa gttattagaa gacaagttag gactacagct gaatcaagct
     6541 cttttaggca ttgatctttt tgtcatgatt gtctctttga cttatatttc cctgccgcaa
     6601 atgatgtatg ctctgattgc tagctttatg tatggtcaaa ttgttcgctt ggtacaacaa
     6661 ggtggttatt cagcccgtgg catttttatc gtttcagaac aagcggagaa aattgcccgg
     6721 ttcatcatgg acgaattggg aagaggagtt acttatctaa caggtgaagg agcctactct
     6781 ggtcgccgta aaaaagtgat ttatgtggct ttggggcgaa gagatattag ggaattaaaa
     6841 gcttttttaa ctcaggttga tcccaatgcc tttatcactt attttgatgt taatgaagtc
     6901 aatagcccag aatttttaac tattaaaagc aaataccata aaaagagaaa ataaatgagc
     6961 attagagttg cctgcgaaga atagtgagga taaaggatgg cacatcacga taaattgact
     7021 aaactactaa aactgttttt gattgcccta ggtgtagcca tttatacctt cggttttgtt
     7081 aattttaaca tggctaatgc tttggctgaa ggtggtgtgg caggaataac cttgatttta
     7141 cacgcgcatt ttgggattaa tcctgcttac tcttctctct tatttaatct tccacttttt
     7201 attttagggg caaagatttt tgggaagcgt tctttggctc taaccatcta tggaacagtt
     7261 ctgatgtccg cttttatctg gatgtggcaa aaagttccta tcgaacttgg cttggaaaat
     7321 gacatgatgt tggtggctgt agtggcaggt ctcttttcag ggattgggag tggcattgtt
     7381 tttcgctatg gtgcaaccac aggtggaacg gatattattg gtcgcattgc agaagaaaaa
     7441 tttggagcta agctaggtca aactttgctt ttggtggatg ctcttgtatt gacagcttcg
     7501 ttgacttatg tggatttaaa acacatgctt tacactttgg tggcaagctt tgtttttagc
     7561 caaatgatta gtgtggttca aaatggtggt tacactatcc gtggaatgat tattattacc
     7621 aagcattcag aggctgccgc tcaagctatc ctaaccgaaa tcaatcgtgg agtgacttac
     7681 ttgaaaggtc aaggagctta ctctggtaat gattacaata tcatgtatgt gaccttgaac
     7741 ccaactgaag ttcgggaagt caaacgtatt ttagctggtt tggatccaga tgcctttatc
     7801 tccattattg atgtggacga agttattagc tctgatttta aaattcgccg aagaaattat
     7861 gataaataaa aatacaggtc aaacagcctg tatttttatt ttggtccccc acttaagaaa
     7921 ctaccaagca taatagctga tatagcagtt cccttgtaat ggctagcttt tgtttttacc
     7981 aagcgactaa gatcaaatat gcttttagga gcatcaaatt gatgtgttaa gatgtattga
     8041 ttgataagtg agtcaatttt tgtagctagg agtgagctca tcccctcttt ttcaagttga
     8101 ctggcgagct cgaagatcgc ttgacgaaaa taatcatctg cttgtattac ttgttcgcta
     8161 taaactttac taagagcatc taatatttct ttttctgatg gcatggcatt ctcctgtaac
     8221 atattgtgct attattataa tataaaaaac taagactgtc ataaatgtga cagccttagt
     8281 aatgttatta cttacatttc atttggtgcg tcaacaccga gtaagcgaag cgcttcttta
     8341 agaacagtag cagttgcata gcagagagct aagcggttat cacgttctga gttgtcgtcg
     8401 agaatgcgag tgtgagcata atatttgtta aagctttggg ctaagttaat agcaaattta
     8461 gccataatag aaggctcaaa gttatctgat gttcgcttga taatgcgtgg gaaatcttgg
     8521 ataagtttga taatttccca gctttcagca tcagttaaac tgtaagtggt ggttgcagat
     8581 ggcgtaaagt cagctttacg tagaatagat tggatacgag cgtgagcgta ttgaacataa
     8641 ggtccagttt ctccttcaaa ggaaaccatg gcctcaaggt caaagtcata cccattcata
     8701 cgatctgttt tgagatcgta aaacttgatg gcaccgacac caacagcgtg tgcaacagct
     8761 tctttgtcag caaggtttgg atttttcgct tcaatttgag aagctgcacg gttaatggct
     8821 tcagcaaccg taggttcaag aagaataaca ttacctttac gtgttgataa tttagcaccg
     8881 ccttttgtga caagtccaaa agcaacgtgt gtcatatcat ctgaccaatc gtaacccatt
     8941 tcttttagca ctgcttttaa ttgtttgaag tgagcagctt gctcattacc aacaacataa
     9001 acggatttag caaagtcata agtgcgttta cggtaaagtg cggcagctag gtcacgggta
     9061 atgtaaagag tagcgccatc tgattttttg atcaaggcag ggtgttcaat accatatttt
     9121 tcaagattaa caacttgggc acctttagat tctacaagaa ggtttttagc ttctaataag
     9181 tcaagaacct catccatttt gtcattatag aaggcctcac cgttgtaact atcgaaggtg
     9241 acatgtaatt ggtcataaag tcggttgaac tcaagtaaac tttcatcacg gaaccattgc
     9301 cataattcag tagcttcttt gtcgccatct tccaatttac ggaaccattc acgagcttct
     9361 tcatcaacgg tgggatcagt ttcagcttca gcattgatac gaacgtaaag ttttaagagt
     9421 tcatcaatag gatgtgcctg aacagcagct tcatctcccc attttttgta ggcaacaatg
     9481 agcataccaa attgtttacc ccagtcacca aggtgattga tttttacagg tttatagccc
     9541 attttggcaa aaatgtgagc gagactatca ccaataactg ttgagcggag gtgaccgatt
     9601 gaaaatggct tagcgatgtt tgggcttgac atgtcaatag caacatttcg cccttgacct
     9661 tcgtcttgct gagcatagtc tgaacctgct gtaatcactt gttcaaggac ctgtgaggaa
     9721 atcttagctt tatcaaggaa aaagttgatg taagggccga cagctacgac tttttcaaat
     9781 tggctctcat caatctgttc agctaactcg ctagcaatca tttgaggggc tttgcgaagg
     9841 acttttgcta agctaaaagc tggaaaggca aggtctccca tgtcagaatt ttttggggtt
     9901 tcaagcaagt taaaaatagc atcttgttct aattctggaa caactttagc tatttcactt
     9961 gcgattagag ttttagtatc catacagcgt ctcctaaaaa ttgtttgtca ccctattcta
    10021 acatatttct ttaaaataaa cgaggagagg attgataaat tatactgaaa ctttcaagga
    10081 aatgaattgc ttgaggttgt tgtttttctg aaaatgttat aaaaagagaa atgaggtttc
    10141 ttttcaacag ttttcaagtg aaattctagt tgaatttgat aaaaaattgc tgaaaatagc
    10201 tgggcgaaga tgaaataata cacttttttt gttataattt gagaggataa ttatacaatt
    10261 ggggtgatat atcatgaata aaatggagcg tcaacagcag attaagcgaa tcattcaagc
    10321 agagcatatt ggcacacaag aagatattaa aaatcacctt caaaaagaag gcattgtggt
    10381 cacccaagca actctatctc gggacttaag agaaattggc cttttgaaat tgagagatga
    10441 acaaggcaaa ctctattata gtttgtctga acccgttgca acaccattta gtcctgaggt
    10501 gcgtttttat gttttgaaag ttgatcgagc aggttttatg ctggttctcc ataccaattt
    10561 aggagaggct gatgttctag ctaatttgat tgacaatgat gccattgaag atattctagg
    10621 aaccattgct ggtgcggata ccttgcttgt gatttgcaga gacgaagaga ttgctaaacg
    10681 ctttgaaaaa gatttggctg caggcctatg actagctatt aagagtcttt gacacaattg
    10741 attcttgcta tccatgaatt ctagtatcgt tgcttataaa gaagtgcagc aatagctgtc
    10801 taagctccat gattttaaaa agtaagctta tcagatgaaa cgctatcaac aagatgccct
    10861 gcttttcaaa aaaaatagat aaagaaaagg ctgcgacagt atctgcaagc agggcaaaag
    10921 aactagaaga taggctcagt catcagccat taattgatga ttatcgagaa aagatgcaag
    10981 atgcaagtga tgtgattcag tatatcacca aacgtataga agatcagtta aacaaggagt
    11041 taacaaatgg caaaaactaa catttctcct ggaatgcaac agtatctgga catcaaaaaa
    11101 gattatccag atgctttttt gctttttagg atgggtgact tttatgaatt attttacgag
    11161 gacgctgtca aagcagcaca actcttagaa attggtttga ccagtcgcaa caagaatgcg
    11221 gaaaatccaa ttcctatggc aggcgtgcca catcattctg cccaacaata cattgatgtg
    11281 ttaattgagt tgggttacaa ggttgctgtc gcagaacaaa tggaagaccc aaagcaagct
    11341 gttggggtgg tgaagcgtga ggtcgttcaa gtcataactc ctggaacggt tgtggattca
    11401 gctaagccag atagcgccaa taactttttg gtagctgttg actttgatgg ttgccgttat
    11461 ggattggctt atatggatgt atccacaggt gaattttgcg tgacagattt ggcggacttt
    11521 acgagtgttc gtagcgaaat ccaaaacctc aaggcgaaag aagtcttact aggttttgat
    11581 ttatctgaag aagaacagac gattttggtc aagcagatga atttgctgct ttcttatgaa
    11641 gaaacggtct atgaagataa atctttaatt gacggccaat tgacaacggt agaactgaca
    11701 gcggcaggaa aactcttgca atacgttcac aaaacacaaa tgcgagaact cagccacttg
    11761 caagcattgg ttcactatga gatcaaggat tatttgcaga tgtcgtatgc cactaagtca
    11821 agtttagatt tggtagaaaa tgctaggact aataaaaaac atggaagtct ctattggctg
    11881 ttagatgaaa ccaagacagc tatggggatg aggcttttgc gctcatggat tgatcgacct
    11941 ttggtttcta aagaagctat tttagagcgt caagaaatta ttcaagtttt tctgaatgct
    12001 tttattgagc gaaccgattt aagcaatagt ttaaaaggtg tttacgacat cgaacgctta
    12061 tctagtcgcg tgtcttttgg caaggcaaat ccgaaagatt tacttcaatt ggggcatacc
    12121 ttagctcaag tgccttatat caaagctatc ttagagtctt ttgacagtcc ttgtgttgac
    12181 aaacttgtca atgatattga cagtttgcct gagttggaat acttgattag aacagccatt
    12241 gatccagatg caccagcaac tattagtgaa ggaagtatta tccgcaatgg ttttgatgag
    12301 cgcttggacc attatcgtaa agtaatgcga gaggggacag gctggattgc ggatattgag
    12361 gccaaagagc gtcaagcaag tggcattaat aacctaaaaa ttgattacaa taaaaaagat
    12421 ggttattatt ttcacgttac gaattcaaat cttagcttag ttcccgagca ttttttcaga
    12481 aaggcaactt taaaaaattc tgaacgttat ggaacagcag aattggctaa gattgaaggt
    12541 cagatgttag aggctaggga agagtcatct agtttagaat acgatatttt tatgtgtatt
    12601 cgagctcaag ttgaaaccta tattaatcgt ttacagaaac tggctaaaat tttggcaacg
    12661 gtagatgttt tgcaaagttt agcagtcgtt gctgaaacca atcattatat ccggccgcag
    12721 ttcaatgata atcatgtgat tacaattcaa gaaggtcgtc acgcggttgt tgaaaaggtt
    12781 atgggagtgc aggaatacat tcccaatagt atctcttttg accaacagac cagtattcag
    12841 ctgattacag gtccaaatat gagtggtaag tcgacttata tgagacagct ggccttaacg
    12901 gttatcatgg cccagatggg ttcatttgtg gctgctgatc atgttgattt acctttattt
    12961 gatgcgattt ttacgcgtat tggggctgct gatgatttga tttctgggca atcaaccttt
    13021 atggtggaga tgatggaagc aaaccaagca atcaaacgcg caagtgacaa ctctcttatt
    13081 ctatttgatg aactgggacg aggcacggca acttatgatg gtatggcttt agcccaggca
    13141 attattgaat atatccatga tagagttggt gctaagacca tatttgcaac gcattatcat
    13201 gaattgacag acttgtcaac taacttgaca agtctagtca atgttcatgt agcaacgctt
    13261 gaaaaagatg gcgatgttac cttccttcat aagattgctg agggaccggc ggataaatct
    13321 tacggtattc atgtggcaaa aatagcagga ctgccaaaat ccctattaaa gagagcagac
    13381 gaagttctga cccgtttaga aacacagtca cgatctactg agataatatc agtcccttca
    13441 caagttgagt caagcagcgc tgttagacag gggcaattat ccctttttgg tgatgaagag
    13501 aaagctcatg agattaggca agcactggaa gttattgatg tcatgaacat gaccccgctt
    13561 caagcaatga caactcttta cgaattgaaa aagttgttat agtctttcag ctgaaaatga
    13621 aaaagatgct ttctatattg aaggcatctt tttgttctgt caaaaacggt ccgaggcctt
    13681 cggctattta ttaagtgtgt tataatagtc cataagaatg cgaggaaatt atgacaaaca
    13741 ttattgaatt accggaagtt ctcgccaacc aaattgcagc tggtgaagtt gtagaaaggc
    13801 cagcgagtgt tgtcaaggaa ttggttgaga atgctattga tgctaaaagt agccagatta
    13861 ccgttgaaat tgaagagtct ggccttaaga tgatacaggt tacagacaac ggtgagggaa
    13921 tgtctcatga agatttacct ttaagtctgc gtcgccacgc tactagtaaa attaagagtc
    13981 agagtgattt gtttagaatt agaacacttg gcttccgtgg agaggcttta ccgtctgttg
    14041 cctctatcag taaaatcacg ataaaaacag caacaaaaga agtcactcac ggttctcttc
    14101 ttatagctac tggtggggaa attgagacac ttgaagcgat ctcaactcct actggaacca
    14161 aaattaaggt tgaaaacctt ttttacaaca cgcctgctcg tctcaaatat atgaaaagtt
    14221 tacaggcaga attagctcac attgtagatg tggtcaaccg gttgagtttg gcacatccag
    14281 aagttgcttt cacactgatt agtgatggtc gccaattaac tcagacatca ggaactggcg
    14341 atttacgcca agcaattgca gggatttatg gtttgaatac taccaaaaaa atgctggcta
    14401 tctctaatgc tgatttggat tttgaagttt ccggctatgt tagcttgcca gagttgacac
    14461 gcgccaaccg taattacatg acgattttgg ttaatgggcg ttacatcaag aatttcttgc
    14521 ttaatcgagc aattcttgat ggttacggtt ctaagctcat ggttggacgt ttcccaattg
    14581 ttgtgattga tattcagatt gatccctatt tggccgatgt caatgttcac cccacaaaac
    14641 aagaggttcg tatttcaaaa gagcgtgaat taatggcttt aattagcacg gctatttcag
    14701 agagtcttaa ggaacaagat ttgattccag atgctctgga aaatttagcc aaatcaagca
    14761 cacgacattt ctctaaacca gagcaaacac aacttccttt acagtctagg ggactttatt
    14821 atgatcctca aaagaatgac ttttttgtca aagagtcggc tgtctcggaa aaaatacctg
    14881 aaactgattt ttattccggc gctgttgaca acagtgtaaa ggttgaaaaa gtagagctgt
    14941 taccccactc agaagaagtt ataggacctt cttcggttaa acacgcaagt cgtccccaga
    15001 atacctttac cgagactgat catcctaatc ttgacttaaa aaacagacaa aagttatctc
    15061 aaatgctaac ccgtttggaa aatgaagggc aatcagtgtt tcccgaattg gattattttg
    15121 gtcagatgca cggaacttat ctctttgctc agggaaaaga tggtttattt ataattgacc
    15181 aacacgctgc ccaggagcgg gttaaatacg aatattatcg tgataagata ggtgaggttg
    15241 acagtagttt acagcaattg ttggtgccct atttgtttga gttttctggt tctgatttca
    15301 ttaacttaca ggagaaaatg gcactcttaa atgaagttgg tatcttctta gaagtttatg
    15361 ggcacaatac tttcattttg agggagcatc ctatctggat gaaagaagaa gagattgcat
    15421 ctggtgtcta tgaaatgtgt gacatgttac ttctaaccaa tgaggtatct attaaaactt
    15481 accgagcaga gttagctatt atgatgagtt gtaaacgatc tatcaaggca aatcatagct
    15541 tggatgatta ttcagcaaga aatctgctac tgcaattggc ccaatgtcaa aatccttata
    15601 actgccctca tggtagaccc gtattgatta attttagtaa ggcagatatg gaaaaaatgt
    15661 tccgtcgaat tcaagaaaat cacactagcc tgcgagagct aggaaaatat tagagaggat
    15721 gagatgcaag agtttttaaa ccttcctaag cagattcagc tgaggcaact ggtacgcttt
    15781 gtgaccatta ccttaggcag tagtatcttt ccctttatgg ccatgtatta tacgacttac
    15841 tttggtacgt tttggacagg cctcttaatg atgattacca gtttgatggg atttgttgga
    15901 actttatacg gtgggcatct gtcagatgct cttggtcgca aaaaagtcat tatgattggg
    15961 tcagtaggaa caacactagg ctggtttctg actattttag ctaatttgcc taatgcggct
    16021 attccttggt taacctttgc gggtatttta ttggtagaga ttgcttctag tttttatggt
    16081 cctgcctatg aagctatgtt gattgatttg actgatgaga gtaatcgtcg atttgtttac
    16141 accatcaatt attggtttat caatattgcc gtcatgtttg gtgcagggct atctgggctt
    16201 ttttatgacc atcatttttt agccttgtta gtagccttat tactcgtcaa tgtactttgt
    16261 tttggcgttg cttactactg ttttgatgaa actagaccag aaacacacgc ttttgaccat
    16321 ggtaaaggat tactggcgag ttttcagaac taccgtcagg tgtttcatga tcgtgccttt
    16381 gtcttgttta ccttaggtgc catcttttct ggtagtatct ggatgcagat ggataactat
    16441 gtgccagtcc atttgaaact gtattttcag ccaacggctg tgttaggttt ccaagtaact
    16501 agttctaaaa tgttatcatt aatggtttta actaatacat tgctgattgt ccttttcatg
    16561 acagtagtaa ataaattaac ggaaaaatgg aaactattac ctcagcttgt ggttggttct
    16621 ttactattta ctctagggat gctcttgtca tttaccttta cgcagttcta tgctatctgg
    16681 ttatcagttg ttttgttaac ttttggggaa atgataaatg tttctgctag tcaagtccta
    16741 cgtgctgata tgatggatca ttcccaaata ggatcttata caggttttgt gtcaatggca
    16801 caacccctag gtgctatttt ggctagtcta ctagtatctg tcagccattt tacaggtcct
    16861 ttaggcgtgc aatgcttatt tgcagtcatt gctttgctag ggatttattt tacggttgtt
    16921 tctgcaaaaa tgaaaaaggt gtaatatgta cgattatatt aaaggtcaat tgaccaaaat
    16981 tacggcaaaa tacattgtcg ttgaagctaa tggattgggc tacatgatta atgttgccaa
    17041 tccttatagc tttacagata gtgtcaacca attggtaacc atttatctgc atcaagtgat
    17101 tcgtgaggat gctcacctgt tgtttgggtt tcacacggaa gatgaaaaag atgtttttct
    17161 gaaattaatt tctgtatcag gtattggtcc gacaacagct cttgctattg tggcagttga
    17221 tgataatgag ggacttgtga atgccattga taacagtgac attaagtacc taatgaaatt
    17281 tcctaaaatt ggtaaaaaaa cagcgcagca aatggttctt gacttagctg gcaaatttgt
    17341 ggaggctcca caagagactg gtcataccaa agcgcgcagc aataaagcag gcaatactca
    17401 actggacgaa gcgattgaag ccctccttgc tctcggttat aaagcaaaag agctgaaaaa
    17461 aattcgtgcc ttctttgagg ggacctctga gacggcagag caatacatca aatcagcatt
    17521 gaaactgtta atgaaagggt aggtgtttca catgaaacgt tgctcatggg ttcctaagga
    17581 taaccagctt tactgtgatt accacgattt agaatggggt caacccctgg atgatgatag
    17641 agattttttt gaattgctgt gccttgaaag ttaccagtca ggcttatcct ggctgactgt
    17701 tttgaaaaaa cgccaagctt tcagaactgt ttttcatcat tacgacattg catcggttgc
    17761 aacctttacc tcggaggaaa tggctgatgc tttagagaat ccatccatta tccgccacaa
    17821 gctaaagcta gcagcaactg tcaacaacgc tatcgcagta cagaaaattc aaaaagagtt
    17881 tggtagtttt tcaacttatc tctggaattt tgttggggga aagccaatta acaaccttgt
    17941 caatcaagag aatcttgttc ctgctcaaac agaattatct attcgcttag ctaaggattt
    18001 aaagaaaaga ggatttaaat ttttagggcc tacaacggtt tattctttta tgcaagcatc
    18061 gggtctggta aatgaccatg aagaggcttg tgttttcaat agaatcttct aattcttcgt
    18121 gaattggaag attttttgat aaaatgagat cagattacga atagataagt aggtagggaa
    18181 atgaaagctg aactgattgc agtaggtacc gaaattttga ctggtcaaat tgtgaatacc
    18241 aatgctcaat ttctgtcgga aaaaatggca gagctaggta ttgatgtcta ttttcaaacg
    18301 gctgttgggg acaacgagga gcgtttactt tcagtgatta caactgctag tcagcgtagt
    18361 aacttggtaa ttttatgtgg tggccttggt ccaacgaaag atgatttaac caaacaaact
    18421 ttagcaaagt accttaggaa agacttggtt tatgatgagc aagcttgtca gaaactagat
    18481 gacttttttg ctaagcgcaa gccttcatca cggacaccaa ataatgagcg acaggcacaa
    18541 gtgattgaag ggtcaatccc tttgccaaat aaaactggtc ttgcggttgg tgggttcatc
    18601 acagtcgatg gtattagtta tgttgtctta ccgggtcctc caagtgaatt gaagccgatg
    18661 gtaaatgaag aattggtacc acttctgtca aaacaataca gtacattgta ttcaaaggta
    18721 ctacgctttt ttggtattgg ggaaagtcag ttggtaacag tcttgtcaga ttttattgag
    18781 aatcaaactg atccaaccat tgctccgtat gctaagactg gcgaagtgac tcttcgctta
    18841 tcaacaaaaa ctgaaaacca agctctggca gataaaaagt taggtcagct agaagcgcag
    18901 ctactatccc gaaaaactct tgaaggtcaa cccttagctg atgtctttta tggctatggg
    18961 gaggataatt ccttagcgcg tgagacattt gagctcttag taaaatatga taagacaatt
    19021 acagcagcag aaagtctaac cgcgggatta tttcagtcaa ctttggcgag ttttccagga
    19081 gcttctcaag tattcaatgg aggctttgtg acttatagca tggaagaaaa agcgaaaatg
    19141 ctaggccttc ctttagagga gttgaaatcg catggcgttg ttagtgctta tacggccgag
    19201 gggatggcgg agcaagcaag gttattgact ggtgctgata ttggggtaag tttaacaggt
    19261 gttgccggac cagatatgtt ggaggaacag cctgcaggta cagttttcat tggtcttgcc
    19321 actcaaaata aggtagaatc aataaaggtt ttgattagcg ggcgaagtcg tttggatgtg
    19381 cgctatatcg ctactttaca tgcttttaat atggtccgta aaactttatt aaaacttgag
    19441 aatttgctat aatgttattt agtagctata gtaggatatg gtttacaatt atgtagatta
    19501 atcctgctga cgatggtttg ttaaaaaaga ggagaaagta ttggcaaaaa aattaaaaaa
    19561 gaatgaagaa atcactaaga agtttggtga cgaacgtcgc aaagcccttg atgatgcttt
    19621 gaaaaatatt gaaaaagatt ttggtaaggg tgcagtgatg cgattaggag aacgtgcaga
    19681 gcaaaaagtt caggttatga gttcaggaag tctagctctt gatattgcgc ttggagctgg
    19741 tggttatcct aaaggacgta tcatcgaaat ctatggtcca gagtcttccg gtaaaacgac
    19801 tgtggcttta catgctgtag cacaagctca aaaagaaggt ggaatcgcag cctttatcga
    19861 tgccgagcat gcgcttgatc cagcttatgc tgctgcgctt ggggttaata ttgatgaact
    19921 cctcttgtct caaccagatt ctggagaaca aggacttgaa attgcaggta aattgattga
    19981 ttctggtgcg gttgatctgg ttgttgtcga ttcagtagca gctttagtgc cacgtgctga
    20041 aattgatggt gatattggcg atagccatgt cggattgcaa gcacgtatga tgagtcaggc
    20101 catgcgtaaa ttatcagctt ctattaataa aacaaaaact atcgctatct ttattaacca
    20161 attgcgtgaa aaagttggtg tgatgtttgg aaatcctgaa acaacaccag gtggtcgagc
    20221 tttgaaattc tatgcttctg ttcggctgga tgtgcgtgga acaactcaaa ttaaaggaac
    20281 tggtgaccaa aaagatagca gtattggtaa ggagaccaaa atcaaggttg ttaaaaacaa
    20341 ggtcgctccg ccatttaagg tagcagaagt tgaaatcatg tatggggaag gtatttctcg
    20401 tacaggggag cttgtgaaaa ttgcttctga tttggacatt atccaaaaag caggtgcttg
    20461 gttctcttat aatggtgaga agattggcca aggttctgaa aatgctaagc gttatttggc
    20521 cgatcaccca gaattgtttg atgaaatcga ccttaaagta cgtgttaaat ttggtttgct
    20581 tgaagaaagc gaagaagaat ctgctatggc agtagcatca gaagaaaccg atgatcttgc
    20641 tttagattta gataatggta ttgaaattga agattaaaaa gagcccttca gggcttttta
    20701 aaatgtattt ttaaaggtta gtaggactac tgttcatagg tgtgtgggtg aatagaaacc
    20761 atcatttaaa aagatgtgag agagcagaac ttaggttaac tgatataaaa ttaaaataac
    20821 taataattca agggaataca ggtgaaaaac cttattttac aaagataata tctttaaaat
    20881 taaaaaaata ggtccaaaga cctatattta tagataagaa actgtgctac aataaagcta
    20941 tcacgaaata gaaagtgagt cagcaacatg attaaaattt acacgatttc aagttgtacg
    21001 agctgcaaga aagccaaaac ttggctaaat gcccataagc ttgcttataa agaacagaac
    21061 ttaggaaaag aaccgctaac taaagaagaa attttagcaa ttttatcaaa aaccgaaaat
    21121 ggagtggaga gcattgtttc atctaaaaat cgttatgcca aagctctcga ttgcgatatt
    21181 gaagaattaa gtgttagtga ggttattgat ttgattcaag ataacccgcg catccttaaa
    21241 agtcccattt tgattgatga taaacgtctg caagtaggct acaaagaaga cgatattcgt
    21301 gcttttttac ctcgctctat tcgtaatatt gaaaatactg aagcacgatt acgtgctgca
    21361 ctctaaaagc tcttgtagag ctttttttaa ataccttctt cgcttgaaat tcttgtttat
    21421 ttaatagaaa taagctataa taaagcatag cacttaattt tagaaagaag gtgtaagtat
    21481 gggatttaca gatgaaacag tccgctttaa gttggatgat ggcgacaaac gacaaattag
    21541 tgaaacatta acagcagtct atcattcact tgatgaaaag ggttataatc caattaatca
    21601 aattgttggt tatgtcttga gtggggaccc agcttatgtt cctcgttata atgatgctcg
    21661 aaatcagatt cgtaaatatg aacgtgatga aattgtagaa gaacttgttc gctactattt
    21721 acaaggaaat ggaattgatg ttaaatgaga ataatgggac ttgatgttgg ctcgaaaacg
    21781 gttggtgtag ctattagtga tcctcttggc tttacagccc aaggacttga aattatcaag
    21841 attgatgagg aaaaagcaga atttggcttt acacgtttag aagagcttgt taagcagtac
    21901 caagttgaac agtttgttat tggattgcca aaaaatatga ataacaccaa tggtccacgt
    21961 gttgatgcaa gtataactta tggaaaccac atagagcacc tctttggact tccagtccat
    22021 tatcaagatg aacgattgac gactgttgag gcaaagcgta tgcttattga gcaagctgac
    22081 attagtcgtg gtaagcgaaa aaaagtcatt gataaattag ctgcacaact cattttacag
    22141 aactatttaa atcggaattt ttaaggagat aaaaaatgac acataatcat gaaaatgacc
    22201 accaacacga agttatcaca cttgtggatg aacaaggaaa tgaaaccttg tttgaaattt
    22261 tattaacaat tgatggtcgt gaagagtttg gtaaaaatta tgttctcttg gttccagcgg
    22321 gatctgaaga agatgagtct ggtgaaattg aaatccaagc ctattcattt actgaaaatg
    22381 aagatggtac tgaaggggat ttacaaccga ttcctgagga ttcagatgct gaatgggata
    22441 tgattgaaga ggtatttaat agttttctag atgagaacta aattgttagt gacactatgt
    22501 taaaaagtag ccgtgagggc tattttttta atgttatttt cgaataaata agcaggaggt
    22561 ga
//
LOCUS       DAUGQX010000031        21179 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUGQX010000031 DAUGQX010000000
VERSION     DAUGQX010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21179
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.031"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(220..519)
                     /locus_tag="VIA51_001188"
     CDS             complement(220..519)
                     /locus_tag="VIA51_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683131.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(676..1143)
                     /gene="perR"
                     /locus_tag="VIA51_001189"
     CDS             complement(676..1143)
                     /gene="perR"
                     /locus_tag="VIA51_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEQ8683132.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(1195..1650)
                     /locus_tag="VIA51_001190"
     CDS             complement(1195..1650)
                     /locus_tag="VIA51_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEQ8683133.1"
                     /translation="MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNL"
     gene            complement(1837..4479)
                     /gene="polA"
                     /locus_tag="VIA51_001191"
     CDS             complement(1837..4479)
                     /gene="polA"
                     /locus_tag="VIA51_001191"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEQ8683134.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(4610..6337)
                     /locus_tag="VIA51_001192"
     CDS             complement(4610..6337)
                     /locus_tag="VIA51_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEQ8683135.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMTMASGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAKKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(6353..7549)
                     /locus_tag="VIA51_001193"
     CDS             complement(6353..7549)
                     /locus_tag="VIA51_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8683136.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(8037..9128)
                     /gene="ulaG"
                     /locus_tag="VIA51_001194"
     CDS             complement(8037..9128)
                     /gene="ulaG"
                     /locus_tag="VIA51_001194"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEQ8683137.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(9381..11027)
                     /locus_tag="VIA51_001195"
     CDS             complement(9381..11027)
                     /locus_tag="VIA51_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEQ8683138.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(11352..12056)
                     /locus_tag="VIA51_001196"
     CDS             complement(11352..12056)
                     /locus_tag="VIA51_001196"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEQ8683139.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVARMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(12058..12921)
                     /locus_tag="VIA51_001197"
     CDS             complement(12058..12921)
                     /locus_tag="VIA51_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEQ8683140.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPAIEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(12926..13588)
                     /locus_tag="VIA51_001198"
     CDS             complement(12926..13588)
                     /locus_tag="VIA51_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEQ8683141.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     MKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(13679..14164)
                     /locus_tag="VIA51_001199"
     CDS             complement(13679..14164)
                     /locus_tag="VIA51_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8683142.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALVTLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            complement(14287..14565)
                     /locus_tag="VIA51_001200"
     CDS             complement(14287..14565)
                     /locus_tag="VIA51_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8683143.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(14636..16069)
                     /locus_tag="VIA51_001201"
     CDS             complement(14636..16069)
                     /locus_tag="VIA51_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8683144.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(16376..18877)
                     /locus_tag="VIA51_001202"
     CDS             complement(16376..18877)
                     /locus_tag="VIA51_001202"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEQ8683145.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASA
                     IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(19088..20227)
                     /locus_tag="VIA51_001203"
     CDS             complement(19088..20227)
                     /locus_tag="VIA51_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEQ8683146.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELAQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMSFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
BASE COUNT         6257 a         4658 c         4042 g         6222 t
ORIGIN      
        1 aacttcctca ttatgcattt aaaaatatta atacatagat tcactaagaa tctctttttc
       61 gagctttttg ttttttaatt tttcaagttg aataattaaa ccttgctttt ctttttcaag
      121 gtaatagact ctactccttg taagtctaac ttattcttaa tcttatttat cgctcatttt
      181 ttaaattccg atgctctcac agatattatc attgtttagt tacatgtctg tcaatctatt
      241 cgccaccaca ctaggggcca tctgattgaa aaataaaatt tcggagtcca ttgtttgctc
      301 aagaatcata tctgtcacaa ttacgtcata ctctgaagac agtgacacca tatcaaccat
      361 ggtcagcctc aagtcatcaa agttgataat ctcaaaaaat cctccaaaat actcttttaa
      421 gaagttgcca acattgttat aacttctctc aaccactaat agtttcaagc gacgacgcga
      481 ttgatttgta agaaagagat tttcccaggt gaggaacaaa caaatagagg agatgattga
      541 tggttctttc ctttaattcc ttatgatccc cagcaaataa ctctttaaca taagcaacaa
      601 aggtctggta ttgaactggg ggtttttgat ttgtaaaggc actatattta taatgccttt
      661 atttaagggt taactctaaa aatcagattg gtcttttgct tggcaatccg gacaaatccc
      721 gtaagcaata actgggatac gcgtgacctt ataacctgtt tgctcatggg cttctttggc
      781 aatatccata acatcaacat ccataaagtc agcaatcttc ccacatattt cacaaactac
      841 attgacgtgt tgatggccca taaagtcata gtaggtggtt aaatcattgc tgattttcaa
      901 ctctgagaca aaaccttcat caactaaaac tttcaaatta ttatagactg tggcaaggct
      961 catgttagga aagttaggct gtaagtcacg gtaaatctta tcggcactag ggtgttctgt
     1021 ggactgaatc atgtaagaaa taatggcttt acgtgtctct gtaattcgaa tatgtttttc
     1081 ccgtagatgc tctaggacat tttcataggc atctagggct tgctgatgtg aatgaatgtc
     1141 cataagctgc tactcctatc cttttttcct ttattatcac gcacgtctct agtttcaaag
     1201 atttgtgatg cattctggtt tagcgactaa ttgcaaatag tctattttta ggcagcgatt
     1261 catcacaata gcctctttgc ctgccgaccg taaaatggtt tgtacttctt ggttttcaag
     1321 gcctaattgc gcccaaaaga ctttggcctg acctgctaaa aagtctctgg caacttctgg
     1381 taaaaactca cttctgcgaa agacatctac aatgtcaacc tcaaagggaa ttgccttgat
     1441 actggcatag accttctctc ccaaaataag ctgacctgct aatttgggat tgactggaat
     1501 gatccgataa tccatagcct gcataaattt ggcgacacca taagctgctg tgtctttgcg
     1561 gtcagaaaga ccaacaaccg caatggtttt ggctgactcc aagtaagctt ttaggatatc
     1621 ctctgaggga ttttgaaacg aataaatcac ttgttcccct atctatttaa taacctctac
     1681 agctgttcaa tatagcagga taactcctaa agcatggctt caatcacttt taaccttatc
     1741 cgtcaaaaag ctcaaagcag cttcatgact tctcctacaa ttttttagtt tattataaca
     1801 taagttgtca aaatgagaaa taacaagtaa gaaaacttat ttggcttcgt accagctctg
     1861 cccagtactt tcatcgacac ataaaggaac agctaaatca acagcagctt ccatggtgtc
     1921 tttgacaagt ttttttatag cagtcaactc atcatttggc acttccaaaa cgatttcatc
     1981 atgcacttga agcagcattt tagctctaaa accacctgct tgcaaggcct tatccagatt
     2041 aatcatagcg attttgagaa tatcagctgc gcttccttga atgggcgagt tgatggctgt
     2101 acgctccgca aaagagcgaa cgttgaaatt acgagagttg atatccggta attcacggcg
     2161 acgcttaaag agggtctcta catagccctt gtctttagcc tcacgcacca cattttccat
     2221 ataggcttta atcccaggat agcgttcaaa ataggtatca atgtaagact tggactgttt
     2281 acgggtgata ccaaggttat ttgacaaacc aaaatcagaa atcccataca caattccaaa
     2341 gttaacagcc ttggcattac ggcggtcatt ggcagtaaca tctgctgcct tgtcaatccc
     2401 aaacacacgc atagccgttg aggtatgaat gtctgcccct tcattaaagg cagcaatcaa
     2461 atgctcatcc cctgaaatat gtgctagcac gcgcaattca atctgtgagt aatctgaact
     2521 caacaagacg gcatcttcat gagatggggt aaaggcctta cgaatcaaac gcccctgttc
     2581 caaacgaatg ggaatgtttt gaagattagg gtccacacta gacaaacgcc ctgtctgggt
     2641 gagatcctgc acatagcggg tatgaatctt gccatcagcc agaatataat cctgtaaacc
     2701 aatcacatag gtggattgca atttagtaat ctggcggtaa tccaaaattt tagccacaat
     2761 tggagcaatc ggtgccaaac gttccaaaac atcaacagct gtagaataac ctgttttggt
     2821 cttcttagtc atctcaagag gtagttgcat cttctcaaac aagatactgc ccagctgttt
     2881 aggcgaatta atgttaaatt cttggccagc catatcataa atctcttggg tgagcgcttc
     2941 aataatgacc ttgttttgct ctgccatatc ttgcaaagtc gccctattaa ccttgatccc
     3001 ttcaatttcc attttagcaa ggacattagc caaaggcaat tcaatattct gatagaggtc
     3061 tagttgctca tgggcagtga gcttgtctag catttgagac ttgctatcta ataatacttt
     3121 gaccttacga gctaagtgtt ctagtaagac gtctttatca ggaacagccc gtttagcacc
     3181 tttaccatag accgtatcgt cttcttccaa agagatgtca gtaaaaatgc gggcaatggt
     3241 gctaagctca ttgtcttcta cagttgacag aaggtaatta gctagtctag catcatagct
     3301 aggtgctacc aactcaattc ctaagtggct caacaagacc ttgctacgtt taaaatcata
     3361 agtggcaatg ggtttttgga agacctgctt aaaactatcc gtcgctaata ggctaaggtc
     3421 tgtggatgcg taaatctgct caccatgtcc ccaagcaaaa ccaatgatgg cctcacgatg
     3481 gtaattatcc cgaagcgttt caaagtagaa gatgtcttct gcgctaaaca aatcagcaga
     3541 cacattggtc acttcttgat aggaaatgac agctactggc tcttgaggca tctggctagc
     3601 aagacctttc ttgagttgca caaaatccat ctcatcgtaa aattgagaga ggctagcaac
     3661 atctggacca ttgtagacaa tatcatctaa gccaattgtg ataggagatg ctgtattgat
     3721 agtggcgagc gttttagata ggaaagcttg gtcacggtca ttgatcaagt tttctttcat
     3781 ttttgaggtc ttgaatccat caatatgctc gtaaatgcct tccaaactac caaattcatg
     3841 aaggagctta aggcctgttt tttctccaat ttttgtcact ccaggaatgt tatccgattt
     3901 atctcccatc aaggctttga ggtcaataaa ctggtttggc gtcaagccca ttttttccat
     3961 gaggtaagcc ggtgtgaatt cttcaaattc ggcaacccct tttttagaaa tttcaaccac
     4021 ggtattttcg tcagttaact ggatcaaatc tttatcacca ctgacaatgg tcacatcaaa
     4081 aggcacttct gtgcgctccg ccattttatc aagcgtcccg ataatatcgt ctgcttcgta
     4141 gtgttccaac tcataataag caatcccaag ggctgtcaac atctcacgaa tataagaaaa
     4201 ctgctcacga aattcatctg gggttttagc gcgacccgcc ttataatcgg catacatttc
     4261 tgttcggaag gtggttttgc ccgcatcaaa agccaccagc acgtgagtag gccggactct
     4321 tttcatcatg tggtctagca tcaaatgaaa gccataaatg gcattggtat ggagaccgct
     4381 atgattttta aagcggtcaa tttgattgta aagggcaaaa aaggcacgaa aggcaacaga
     4441 ggagccatca attaatagta atttattctt gttttccata gccttattat aacacagagg
     4501 gacgggcttt tctcctttaa gccattggtt ttgctgataa gtaaatggtt aacctaaaaa
     4561 gcctaggaaa attcctagac ttctgtattt gctatttaga caaaagcact tattttgtcc
     4621 aacttgatac tttagatttg tttgcctcta cccatttttt ggcggcagct tctggactca
     4681 tgcctttatt gatgtcaagc atgactgctt ccatatcttt ttgggtccag tggaacttat
     4741 caatgatttt gtagacattt ggaagatctt ttttcaagcc tttacgagca atggtattga
     4801 tgttctcagt cgagccaaag gtttctttag gatctttaag gtacttcaag tcatacttgg
     4861 caaacatcca gtgtggtgac caagctgtca cgacaatagg atcttttttc ttgatcgctt
     4921 gatccaagga agtcgtcatg gctcctgttg atgccgccac taactcccaa ctagatagat
     4981 tatgatactc ttttagagtc tttttggctg ctgccatgat acctgcacct ggttcgatcc
     5041 ctgtgatttt ttgatcggct tgtttgctta aatcctcaat actattaaca tctgtcatgt
     5101 atttaggaac agctaaacca agtttggtcc cttttaggtt aggtcctaaa tcatctaatt
     5161 ttgacttgta tttctgatat tgttggccat gggtgactgg caaccaagca ctagttgaaa
     5221 aatcagcgtt cccatttgca acggtttgcc acatgacagc attgtcaagc ggtgtcaagg
     5281 ttacatggta accttcgttt ttcaaaactt ctgcaatcac atgagttgag gcaacctcag
     5341 aatcccactg cacgtaagcg atgttaacag tttcaccctt atctgccata ccagaagcca
     5401 tagtcataat accgcgtcct aaagcagcta tcaaaaagac agcaagggct gctagaccaa
     5461 tccatttatt ggttttgcca gctttggctt tttcttgagg tttgctattg aacaactgtg
     5521 tcatacggtc aagaacaatc gccaagataa ccaaggcaag accactgaca aatccactac
     5581 caatatcagc gtgttgaagg gctgacaaga cttcacgtcc taaaccagga gcaccaatca
     5641 tggagcctgt tactaccatg gaaagggcta acatcatggt ctgattaaca cctgccataa
     5701 tagtattttt agctaaaggc aattcaactt taaagagctt ttgtttccca gttgacccaa
     5761 aggcatctga ggcctcaatc aattctgttg gaatgtcacg aatggccaaa tttgtaaaac
     5821 gaactgttgg gggcaaggca aagatgactg aagcaaatac tccaggcacc ataccaatac
     5881 caaaaaaggc aacggcagga atcaagtaaa caaaagccgg catggtttgc ataaagtcca
     5941 aaataggatt cacaatctga cggacagtgg catttttagc catccaaatc cccagcggaa
     6001 taccaataag taccgaaatc aaactagcta ctaacaccag agtaaaggta ttcattagct
     6061 gcttccataa cccttgattg taaataaaga gcaatcctaa caaggtaaag gttggcaaag
     6121 gccatttttt cttagcaagg aaaaacatcc ctgctgttac tagaacaata aaaagtaacg
     6181 ggtggataaa taaaagtgtt ttggtcatcc aatccatcaa aaagctacca actacttgca
     6241 taatatcaaa tagacctgag aaagttttag ttagccactc cgttagctgc tccaccagtt
     6301 gagctactgg taattttgtt tgtaatatcg tttccaaaat gcatcactcc ttttagttaa
     6361 ggtcttcgtc tgagatatta gccaaggctt caatcactcg tcctcgaata atgacaccta
     6421 acagacgatt attatcatct gtcactgcaa tcggagcaga tgaatcatag ataagaggca
     6481 aaatatctgt aataatagta tcttttgaga cagttctcac atcgcgatca atcacttctg
     6541 atagcggtaa cccttttttg cgcgcctcta tagcggcatc ggccgtcaaa ctgccgacta
     6601 attggcggcg gcgattcgtc gccatcaaca tagacacctc ttcgttgtgc atacggttca
     6661 aggcaacttg aggtccatct aattcaacag tagttgttaa cggtttgatc atgatatttt
     6721 gtgctgtcaa gactttagaa cggtccacat cctcaacgaa ttcacgcaca aagtcattgg
     6781 ctgggttagt caagatttcc tcaccagtac caatttgcat aatttgtccg tctttcatca
     6841 aagcaatccg atcaccaatc cgcaaggctt cattcaagtc atgactgata aagatgatgg
     6901 tttgtttcat gctgtcttgc aaatcaagta attcatcttg catctcacga cgaatcaaag
     6961 gatcaagcgc tgagaatgcc tcgtccatta agagaatttt agggctatta gctagcgcac
     7021 gggctaggcc gacacgctgc tgcatcccac cagatagttg gtttgggtac tggtctttaa
     7081 aatctaatag gcctgaatta tcaagggctt tttctgccaa tcgctggcgt tcttctttgg
     7141 gaacgccacg taattccaaa ccaaattcgg tattttccaa aatggtttta tgaggaaaga
     7201 gggcaaagct ttggaaaacc atgttaatgt catggcggcg cacctcacgc agctgatctg
     7261 ctgacatggt tgagatgtct ttaccttcca gcaagataga tcctgctgaa ggttcaatca
     7321 aacgatttag catgcggaca agggttgatt tcccacttcc tgatagcccc ataataacaa
     7381 agatttcacc ttttttgacc tcaaaactag cgtcatagac acctacagta gcgcctgttt
     7441 tcttaaaaat ctcactctta tttttgccag tctttaccat ctcaagagct gctttttgtt
     7501 ttttgccaaa aattttactg agatgtttga cttctaaaat tgtttccatt cgttttttct
     7561 cctaggtaat cgtttatcat gtgaaataat gacatagctt tggcgaaata ttagccaata
     7621 tttaacaaag tagctctaca caattaataa acgtgtggtc acttttttac ttaaaaaaag
     7681 aatctgccga aacagaacat aactatatta tcacgtgtgg tcactttttg tcaaggacaa
     7741 taactcgatc tggtaatgcc acaatgatag gtgatcgctt tcattctttt aggtatggtc
     7801 ttttaaccag tacaattttt tatcacaact gatggctatt tctttgctga ttaggctatt
     7861 gttacattag aaatccttct tttacctata atatctcttt tgcggccatc gtaaataacg
     7921 accacggtga ctcttaaaca tttgctcatc tctccaaaaa aactcaccta agacagtgtc
     7981 ctatgaagcg agttagctta atcaggcact atcatcttag gtgagtaggg tgttgcttat
     8041 agtaaagctt taaattggat attagaatct tctaagaagc agtcatcaaa tccacgagga
     8101 tgatggtatt cgatacgatt ttggtcttgt ggataggtgt acttgccacc aacctcccag
     8161 ataaagggat ggaaatcgta ttggagacgt tctttgcgca ttttccacag ttcaaggatt
     8221 tcatctgttg atgccataaa gtttgaccaa atgtcataat gaactgggat aacgacttta
     8281 gcacggagat tttctgccat acgaagaagg tcaacagaag tcatcttgtc ttgaattcca
     8341 attgggtttt ccccatagtt atttaacaca acgtcaatat cataatcacg tccatgttta
     8401 gcaaagtagt tcgaaaaatg agaatccgca ccatgataga tggtaccacc tggtgtttca
     8461 aaaatatagt taacagcttt gcgagccatg tcatcatctg tgatagctaa acctgctaaa
     8521 tcaccatctt gagcatcagc tccttgtatt gggagagtta ccagacaggt gcggtcaaac
     8581 gactctacag cggtgatctt aatatctttg aattcaaagc tatcacctgg ctttaagatc
     8641 ataatacgat cttttggcac accccaattt ttccaaactt caccacattc ataaggtcct
     8701 acaaatttaa catgattaag ttttgggtta ttgataatgg ctgccgcagt attgatatcg
     8761 atgtggtcac tatgataatg agaaaccaaa taataatcca actcattaat cataaatgga
     8821 tcaatcacca ttggttgggc cctaagattg ggctgtaatt tacgagctcc tgccatatta
     8881 gccatttgat gtccacgaac catatcctta acttgcttgg tcgctttccc acgatttgac
     8941 cataagtcca tgacaacatt agcaccgcct ggtgtcttaa tccagatacc acagtttcct
     9001 aaccaccaca tcgcaaagtt gtcagctggc acgacttctt gctcgatttc ttcatttaac
     9061 catgttcccc attctggaaa cgtgttaagg atccatgatt cacgtgtaat atcttgtact
     9121 ttagtcatta gggtttcctc cgaatttgtt cttcatttct atactttaag tatagacttt
     9181 cttgtcaatg ataaaaagac caagtgtcac acagatctgt gttcaaaagt ggactgactt
     9241 tttcattagc tcagtctaat actgtctcat tttgcacact gtatcttgca tcaatactgt
     9301 attcaaagct atattaaaaa cctcagttat atttttctat gtcatagaaa actgaggtac
     9361 tttgacgact taacacttac tcatagcagc tcgcgatgaa tgagtttttc aattttagaa
     9421 accaaggcat aacgatctga ttcatctttt acaacagctt caatagcttt tgtgagctct
     9481 gtagaaaagc gggagtgctc actcaagcgt ccttgctttg aaaagcgtat caatttgatg
     9541 atatcatcgt cacttaaaat agggttaaca ataagcatcg ggattttagt ctttagcgta
     9601 tctgtagtag caacaatcat atcgactgct aaaaggtcgt aaacactctg atactgttct
     9661 gtcgtaaaaa cagcttcaat ctgaccattt gctagatacc tttgacactg tttgaacaat
     9721 aacttttgaa tgcctatccc atcatctgaa acaataacga gtttggtctt ttcttgctct
     9781 gtattattgt gacgcagctc tcccccaaga tggatagtca agtaggcaat atcatcgtct
     9841 gtcaagctaa tcgtccaatc ttgttccaaa atagtggcac aagattgagt catagcaaac
     9901 aattcttcgt atttttcttt aatatggtct gttaagggat taactaaaaa aatcccataa
     9961 gctttacggt aaacgagcgc cttacagtgg gtcgtcaact gcttcagcaa atcctgttta
    10021 tgcgtgaaat gtaactgata acggctctcc aactggtcaa taaagtgact aatggttgct
    10081 cgcatgtcgt cataatcttg actttccacg tgatgatctt gatcttttcg aaaagacaac
    10141 atcaacatcg ctaccatact aacttcgata tcatccaaat gaagcttaaa attatggtaa
    10201 agctctctag ctaaatcctg agcaatgtga tattctttac gtttccaaat caaatgaaat
    10261 tcttgtttaa gagcagactt tgtttctgaa tcaagacgca tattacgata acttaaaagc
    10321 atgaaaggta aaatctgcaa catgaattgg ctatcttggg tattaattgt ctttcctaaa
    10381 ctagcttgag ataaaaagag atactcatga aaataggtca aaatatcttt agaaaaataa
    10441 accgataagc cttgtatctc tgagagttta cggttgaata tatcaataaa gctagtattg
    10501 ccaccttggt aaacgtccac taacaatttg tacaggtatt gaataagagc cattggatga
    10561 caaccaaaat aatatcccct agcctttgtc gcatgaagct gaatcttgta ttgtttgtct
    10621 tccagttctt cccttaactc agtcaggtca tttaaaatcg tgttacgaga cacatcattg
    10681 atctgcatca gtttatcaat ggtcacgcgc tcagtggaaa ccgcaatata aatcgaggat
    10741 aggcgtctgc gctcatcact tttcatgaca taattataat cagtcacttc ttctaataat
    10801 aagcgacaag cagctttttg atcagctgtt aaaagaatgc caagtctagg ataagagata
    10861 atctgatcta ctccctttgg caaagcctga ttaattttgt caagctggta ataaacttta
    10921 cgacgtgact gatttaaagc atgagaaatg gccataactg tctcaggtgt ttctagttta
    10981 agtaaataag acagcaagtc ataactcttt ttatctaaaa tcatcatgtt tacaaacctc
    11041 ctctctgaaa atccatcctt gcttatttta tcatgatttc agtgactgcg cagccaagtt
    11101 ttgaaaaact caccataata agattcgctt aatatgattc gagctaatca cctcaactga
    11161 tccaacacca acaccttata tctggtctct aagaactcca caacatacga ttcatccagt
    11221 ttgtgctcat tggcgtttaa atagttcatc gaaaaggaca agtcaaaagg acttgcccaa
    11281 acaatgatta acaaaacctt gaactttctg gcttctagtg agaacctgtg ctaataagcc
    11341 atatcgtgac ctcatttttg accgtaataa gcatttgggc catgtttacg caaataatgc
    11401 ttatccataa tgtatcgtgg cgctggctct acgcgtggat tgatttgttc tgtcaagcga
    11461 ttcatcctag ccacttcttc taagacaacc gagtggtaaa cggcttgctc tggggttttc
    11521 ccccacgtaa atgggccatg attgcgaacc acgattcctg gaaccgccat aggatctaag
    11581 cctcgcttgc taaactcttc taaaatcacg ttgccagttt cttgctcgta agccccatca
    11641 acttctgctt ttgtgagaga acgagcacac ggaactggtc catagaagta gtcagcatgc
    11701 gtagtcccat aaaacggaat atcacgacct gcctgagccc aaccaacagc ttctgtggag
    11761 tgagtgtgga caataccgcc cacttctggc caagctttat aaagttccac atgggttggc
    11821 agatctgaag aagggttcaa atcaccttcg accacattcc catcaaggtc tgtaacaacc
    11881 atgttttctg gtgtcaagag gtcgtagtcc accccagaag gcttgatgac aatacgtcct
    11941 aattcacgac aaacttcaga gacattgccc cacgtaaatt tgacaagacc gtgttgtggt
    12001 agagacttgt tagccgcaca gacacgttca cgcatttctt gcaagttttt cgccatatta
    12061 tgccaacccc gctttctcaa taagtgggta aaggaagtcc tgagcttctt tgatagcagc
    12121 ttttgtttcc tccaccgtgt cacaattttc tgaccacatt tcaatcaaaa aaggcccatt
    12181 gtagttggtt ttcttgagga ccgcaaacag ctcttgccag tccacacaac cttgaccaaa
    12241 tggcacatca cgaaactgcc cttttgaggt ttccgtgaca gcataagtat ctttcaagtg
    12301 gagggctgca atggacttgt gaccattgta aaattcactc cacaaatcat tatgccaggc
    12361 agaaacattg cctgcatcag gataaacaaa gagataaggc gagtcaatct ctttttcaac
    12421 tgccaagtat ttttcaatag agttgataaa agggtcatcc ataatctcaa tagaaagcat
    12481 cacttgggct tcttcggccc agtcacaaga ttgtctcaag tttttgataa aacgagcacg
    12541 ggtttcaggc gatttttctt catagtaaac gtcataacca gctaattgaa tggtacgaac
    12601 gcctaagtcc tgtgccaatt caatacattg tttcatcagt ttaagggact tggcttcaat
    12661 agcaggatca tttgagccta gtgggtaacg tctatgacca gaaaaacaaa tggtcgggat
    12721 gcgaatgcct gtttcataaa tggctttcac taaatcaagc cgttcttcct tagtccactc
    12781 taagcgcgct aagcgagcat ctgattcatc aacagacatt tccacaaaat caaaacctaa
    12841 gtcttttgca aattgcaagc gttcacgcca ggtaaactgt tttggcgttg ctttttcata
    12901 aataccaata ggacgcgcca taaagttacc cccagatacg tttgatttca tctttgaagg
    12961 cacgcgccgc tgcagcagga tcttctgctt cagtaatgcc tcgccctgcg ataaaggtaa
    13021 agacatcaac cccttcaaaa agtttcaaag tgtctacatc aagcccacca gttactgaca
    13081 cgcggaagcc catgtcaatc aatgttttca ccttgttaag gtctttttca ccccaagttt
    13141 ctccagcaag aagggcatca cgtgattggt ggtaaatggc ttgggaaatc ccagcgtcaa
    13201 gccataattg agcttgctca taagtccaat caccataaag ttcgatttga atttccccac
    13261 ggtcaccgcg ctcttctttc atagccttga gggctgcttc catggttgga atcgtcgcac
    13321 agcaaatgca ggtcatccag tcagcaccac gttttgcatt gtttttagcg accgtaccgc
    13381 cagcgtcagc acatttggta tctgctacga taattttctc tgggaagagg ctgcgtaata
    13441 cctcaaccaa ctcgcttccg acttgaagca agcagaccgt accggcttcg ataacgtcta
    13501 cttcgtgacc cacagcaacg gctgctttaa cagccccctg taagtcagaa tggtctaaag
    13561 caacttgtaa atttggaata tgtgtcatct ctttttccta aaactcttag ccaccgtgca
    13621 aactggttaa gagttcttat cctttccatc attcgttagt atcctgtgta aggaaagctt
    13681 aagcattcaa gtccatacct tctaagtaag gactatcttt agattcttct accatttcta
    13741 gaacctcttt aggactttgg caggccacca agcgttcaat ggcgttatct agttcaaaca
    13801 aggccacaat ttgtggaata gccactgttg tgtgaataga agggtctgta gcggccaacg
    13861 tcaaaagaac agaaacctct ttaccatctg agaaggtaac tggttttgtt agtgtaacca
    13921 aagcaaatgc attgcgatta acgcctaaac ctgcttctgc atggggcata gccatacctg
    13981 gcatcaacac ataataaggg ccgtattttt ctgttgatgc aatgatggcg tcgtagtaag
    14041 ctgacgtcac tgctttgcta tcaatcaaag gttgaacagc taattgaaca gcctcttgcc
    14101 aagtatcagc acttagcccc aatcggatgg agttgttgtc aataaaggct tgttttaaat
    14161 tcataaaaac tatctctttc tagtgtcttg ctttgcaaca cacaccattt ttactagttt
    14221 tatcctacta aagagaaaga gctgaaaacc ttcgtcacaa ctccttcgtt ttgattcaga
    14281 attagcttat agcacttctt gtagtttggt tttaatttca ttatcatcca tcaggttatc
    14341 aagaccaacc aagtggcctt tggtacgacc atcaagctca tgaatcaagt gatttgatgc
    14401 cactacaata tcatagccag aagctagacc tttagcttca ccaactgagc aagaagctga
    14461 ctgaatatct gtcacgccaa gttgacgaag cgcattttca actttcattt tgatcaccat
    14521 agatgacccc ataccattgc cacatgctgt taagacttta accattgttt tttcctccga
    14581 aaatgtttta ttattgtttt gttaaaatag cagagctatt tcttaagatg cagtgttatt
    14641 gagcttcccc acggtaataa gcttctttgt ccttagcttt tgcgaattgc aattgtggaa
    14701 tggcaagtaa gaagatgcaa acaagcacat accctgcaat accaaggaat ttgaagaggt
    14761 acccaaatgg taaccatgga agaaccaagt cgatattacc gtgataacca cctgtaagtc
    14821 ctaaaagacc tacagcaaca gcaccaagtg caacttgcaa aatacctgaa ataaatgata
    14881 gagctaccgc tgctttccag ccaccacgtt tatctgcata aaccgcaatt gccgcattat
    14941 caaagaatac gggaacgaat cctgtgataa ttaagattgg atttttaaag ataacaagaa
    15001 gagcaatggt gattaattga ccaatcaaac caaaggcaaa tcctgaaagc accgcatttg
    15061 aagaaccaaa gccataggaa gctgcaacgt caaccgctgg gaatgaccct ggaagcaatt
    15121 tgcttgagat cccttgaaag gcattggtca attcagaaac aaacatgcga acaccctgca
    15181 tcaagataaa gagataaact gagaaggtga gagaggtttg caaaatatac atgaagaaag
    15241 cttgcttagc tgggttgaat gctccaggtc cgattaagtc cacatcagac ataatgtctg
    15301 gaccaaggac agccaagata gctccgaaaa agaccaacat caaagttgct gacgcaacaa
    15361 cagtatcatg gaaaatgttt aagaaggttg gtaattttag gttatcaagg ttttcttctt
    15421 ttttaccaaa gaacggtgca accttatcca caaaccaaat cgcaaattgt tgttggtgac
    15481 caatcgcaaa cccaccgcca cctgtaaggc gttgagttgc ttcaacggtc atgtttgagc
    15541 tgatagccca gtaaagccca cagatgatac cgactgccca tgccccaaaa gcattttgga
    15601 attgagggat taaaagaagg acaaagaccg aaatcgtcgc tgcctgttgg accatgatgt
    15661 gacctgtgat gaaaagggta cgaactttag tgaccttgcg aagtgcaacc aaaagaatgt
    15721 tgaccccaaa tccaatcaag agagctgtcg tagcaacact gatgaagccc atctcttcta
    15781 acttagtatt agcagcagcc aaaccaaaat aaggatcaat aacggcggct ttcaattcaa
    15841 atttcttggc aagagcaacc aagatcggac gaaaagtcgt tacaagaccg cctgctccaa
    15901 cgttcaaaat caagtaacca acggtagcct ttacaaaacc agcaaagacc tcataaatgg
    15961 gttttttaag gagtaaatac ccgattaaaa ccaaaagacc tacaaagaac gctgggtttt
    16021 gcaaaatatt ttgcgagaac cagtttaggg gagctaggag catttccata agaactacct
    16081 cttttcaaag ttaataaaga taaagtgttt atatgttcat tataggtaat gaaagcgttt
    16141 taaaaaagac caactatcac acaaagaagt gttcaatatt agacttaagt taacttattt
    16201 taaaatttaa ctacacttaa taataaggag aaaatcaccc taaacaacga ttaaaaacca
    16261 caagaacctt cgttcttgtg gtttttctag atgagttgct ttttgaatag atcagctctt
    16321 tggcattaac tgtgacgtga cgcaaataac cactgaaggg ctgtgtcacc tcaaactatt
    16381 tgataacaat attaacgagt ttgtttggta ctgcgatgac tttgatgatg tctttgcctg
    16441 cgatttcggc ttggactttt tcgttagcaa gggcaacttc ttgtaattct tcgcgtgaaa
    16501 ggtctttagc aactacaagt ttagctttga ccttaccttt gatttggaca acgatttcca
    16561 catcgttttc aaccaatttg ctttcatcat aacttggcca tggcacgtaa gagattgact
    16621 cacctgaggc tgtcaaggct tgccagagtt cctcacctaa gtgcggtgca aatggtgcaa
    16681 tcaattgaac aaagcctttg gcatagtcgc taaagagttt gtcttccttg ttggctgcat
    16741 tgacaaatac catgagttga gcgatagctg tgttgaattt catttggtca acttgctcag
    16801 taacggcctt aacggtttcg ttgtaaacct tgtcaagggc tccgctattt tcctcagtga
    16861 tctctttagt cgtgatcaaa cggtaaacac ggtccaagaa cttacgtgag ccttcaagac
    16921 cttcttcaga ccaagcgatg gaagcgtcaa gtggtcccat gaacatctcg taaacacgaa
    16981 gggtgtcagc accgtactgc tcaacaacat catctgggtt gacgacgttc ttaagtgatt
    17041 tagacatctt agctggtgct tgttcaagct cttccccagt ttccacatgg aagaagctgc
    17101 catcacgttt ttcaaccttg tcagtcgcta caagcgctcc acggctatcg cggtagcttg
    17161 tccccaaaat catcccttgg ttaaagagtt tttggaatgg ctctttggta ggtacaacac
    17221 cgagatcgta aagaaccttg tgccagaagc gagcgtagag aaggtgaagc acggcatgct
    17281 ctgcaccacc gacatagata tcaactggca accattgttt gaggagttcc tcatcagcca
    17341 gtttttcggt gttgtgtgga tcgatgtaac gaagataata ccagcttgaa cctgcccatt
    17401 gtggcatggt gttagtctca cgacgacctt taacaccatc ttcacgggta acttccaacc
    17461 agtctgtcac gttagcaagc gggctctcac cagtacctga aggacgaata tccttagtta
    17521 ctggaagaac caatggcaat tcactctcag gaaccgctgt tgatgtccca tcttcccagt
    17581 ggatgattgg gattggctca ccccagtaac gttgacggct aaagagccag tcacggagac
    17641 ggtaagtgac attttcatta ccgacgcctt ctgcttcaag ccattcgacc attttggcaa
    17701 tagctgacgc tttgtcaaga ccatctagga agtcggagtt gatgtgaaga ccgtcttctg
    17761 taaaggcagc ctcttcaaca ttaccacctt caagaacagg gatgatgtct aggttaaatt
    17821 gttttgcgaa ttcccagtca cgttcatcgt gggctggaac agccatgata gcaccagtac
    17881 cgtagctagc aaggacatag tccgcaatcc aaactggcat ttctttgccg ttgaccgggt
    17941 taatcgcata gctacccgtc cagacaccag ttttttcttt ggcaaggtct gtacgagcaa
    18001 ggtctgattt gagacttgct tgacgtttgt agtcagccac ggcttctgcc tggtcagatg
    18061 tcgtaatagc atcaaccaag gcatgctcag gagcaagaac ggcgtaagtt gcaccaaaaa
    18121 gcgtgtcagg acgtgttgta aagacagtga agtccttatc tgtatcctta accttgaagg
    18181 ttacattagc gccagttgat ttaccaatcc agttgcgttg catgtccttg attgattctg
    18241 gccagtcaac ttcttccaag tcttctagca agcgctctgc ataggcagtg attttgagca
    18301 tccattggcg catgggtttt ctgacaactg gatagccgcc acgttctgat gtcccatctg
    18361 gaagaacctc ttcgttggcg atagctgttc ccaattcttc aacccagtta acgggaactt
    18421 cagcttcgta ggctagacct ttttcataaa gcttggtaaa gatccactgc gtccacttgt
    18481 agtagttagg gtcagttgtg ttaacttcac ggtcccagtc gtatgagaag ccaagagcat
    18541 taatctggcg tttgaagtta gcgatgtttt cagctgtaaa ctcggctgga tcattaccag
    18601 tatccatagc gtactgctca gcaggaagtc caaaggcatc ccaacccatt gggtggagga
    18661 cattgtgacc ttgggcacgt ttgaaacggc taagaatatc agttgctgta tagccttctg
    18721 ggtgaccaac gtggagacca gctcctgatg gatatgggaa catatctagg gcataaaact
    18781 taggttttga tgcgtctgtt cctgttttaa aggtgtgatt atctgcccaa aaggcttgcc
    18841 atttgggttc aatagcggtg tgatcgtaaa atgtcatgtg aaatctccca tgtaaaaaat
    18901 ctagtcttct tattatagca tgagatgaag cttttaggaa tggtcaagac atgactagca
    18961 ccttggcttt tgagacttca gacgattagc tatttttaaa ccctgcttta gcatcaacca
    19021 tcctcacaaa aagctaataa aaaagccaga cttgctctgt aaacagagcc aatctggaca
    19081 aatagactta aaaagcaagt gcttgctcaa aatcggccaa taagtcttcg atattttcaa
    19141 caccacaaga caagcgcagc aaaccatcaa caaccccttg ttccaaccgc gcttgtgacg
    19201 ataaacaagc atgagacatc gttgctggat gtgacaaaat ggactctact ccacctagac
    19261 taacggctaa aatcggcaac tgaatacgat gggtaaagga catcagctcc tccttagaag
    19321 ccaactcaaa ggataaaaca gcaccaccat tcttagcttg ttgcaggtgg gtatcgtgat
    19381 taggatgact gtctaagcca gggtaatgta ccttaagaac tttggggtgc ttcgctaaat
    19441 agttagcgag ctgctgagca ttttttaccg cttgttccat acggatcccc atagttttca
    19501 tgccacgaag aatcagccaa gcgtcttcga ccccaacaat tgctccaaag tttttttgaa
    19561 aaagcttgag ctggttgtag atagcctcat tattggtagc agctaaacca gctaccacat
    19621 cactatgacc attgataaat ttggtcacac tttctactac aatatccaca cccatagcta
    19681 agggttcttg atacaaactg gtcataaagg tattatcagc cacagttagc acaccataag
    19741 ctttggcgag ttgcgcaagc tctgaaatat cacaaatttt caagagcgga tttgacggtg
    19801 tctctagata aatcatacgc gtattaggcc tgatacttgc ttttactgtt gctaaatcag
    19861 ccatatctac aaagcttgtt tcaatctgat aattgggtaa aatagctgtc gcaaattgac
    19921 aagtccctcc atagacctcc aatgggaaaa tcacatgatc tccagctttt aagagcatca
    19981 aaacagttga aatagcagcc ataccagatg cataagccac cgcataagtc gctttttcta
    20041 aacaggctaa cccgtcttct aaagcttcag tcgttgggtt tgaaaagcgt gtgtacaaat
    20101 gtttttgact aggacaatac agttctgaat tgtggaacgt cgaagtctga tagatgggaa
    20161 ctgaagctgc tcctgtaaac tcgtcaataa ccgtatagcc atgtaataag gtcgtatttt
    20221 ctctcatttc gtgcacctcc gcaatagcgt taactccaat gaactctctt ttagacaatg
    20281 gtcccacccc aatggttgca caaaccaaaa agctcttcaa aaaagcgtga tctgctaacc
    20341 tataagaaaa ataaagaaaa gtagtgggca ccttttaaat ggataatgaa tttttccaat
    20401 aatatcattt ttagatcgat tacgtttatt atacaacctt tagctaagtt tgcaagccct
    20461 tttatcatct ttgaccaagc tgccaacacc tctccagcaa gttaaagtat agctaccttt
    20521 ggccccatcg tctcaaaagc tcaaattatc acactgacag tcctaccttg catcgtcacc
    20581 tactcaatat ggcaatactg ccatcaaaat ttcattaaaa ggtcacaatt tatttcattt
    20641 aatgagaaac agaacttgtt ttcaccatgc gtcttatagt ataccgctaa aatactattt
    20701 atttttagga gagaaatata gtgaaaaaca aattattttt agttgccctt gcgaccgtaa
    20761 ctgtcctagg gccctcttta gcaacccctc atcatcagac cgtgcatgcg gctgagcagg
    20821 caaaagaacc ccaaaccagc tcaatgacgt gtactaacga tggatctgta tgcgctggct
    20881 ggcatagttt atcagaagga gacagtataa cttcaaattc atcttcaaac accaagactt
    20941 ccctgttaaa ctggttatgg agcttaataa caaatttgtg gaattctgca aaaaacttgt
    21001 tcatctaaga tctctataat catatccatg gaatttaaat aaccatctcg tggcggtttt
    21061 ctaatcctag gtcgccacac ttcttattca gataaataat aataaaaaca ttaaaataac
    21121 actttattta ttaacaaaaa gttagtataa tataatcaca atacaaatta aaggagtta
//
LOCUS       DAUGQX010000032        21159 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUGQX010000032 DAUGQX010000000
VERSION     DAUGQX010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21159
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.032"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(527..913)
                     /gene="rplQ"
                     /locus_tag="VIA51_001204"
     CDS             complement(527..913)
                     /gene="rplQ"
                     /locus_tag="VIA51_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEQ8683147.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(928..1866)
                     /locus_tag="VIA51_001205"
     CDS             complement(928..1866)
                     /locus_tag="VIA51_001205"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEQ8683148.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1912..2295)
                     /gene="rpsK"
                     /locus_tag="VIA51_001206"
     CDS             complement(1912..2295)
                     /gene="rpsK"
                     /locus_tag="VIA51_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEQ8683149.1"
                     /translation="MAKPTRKRRVKKDIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2313..2678)
                     /gene="rpsM"
                     /locus_tag="VIA51_001207"
     CDS             complement(2313..2678)
                     /gene="rpsM"
                     /locus_tag="VIA51_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEQ8683150.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2696..2812)
                     /gene="rpmJ"
                     /locus_tag="VIA51_001208"
     CDS             complement(2696..2812)
                     /gene="rpmJ"
                     /locus_tag="VIA51_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEQ8683151.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2838..3056)
                     /gene="infA"
                     /locus_tag="VIA51_001209"
     CDS             complement(2838..3056)
                     /gene="infA"
                     /locus_tag="VIA51_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEQ8683152.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3174..3812)
                     /locus_tag="VIA51_001210"
     CDS             complement(3174..3812)
                     /locus_tag="VIA51_001210"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEQ8683153.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEEFGIAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3962..5266)
                     /gene="secY"
                     /locus_tag="VIA51_001211"
     CDS             complement(3962..5266)
                     /gene="secY"
                     /locus_tag="VIA51_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEQ8683154.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5283..5723)
                     /gene="rplO"
                     /locus_tag="VIA51_001212"
     CDS             complement(5283..5723)
                     /gene="rplO"
                     /locus_tag="VIA51_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEQ8683155.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5937..6119)
                     /gene="rpmD"
                     /locus_tag="VIA51_001213"
     CDS             complement(5937..6119)
                     /gene="rpmD"
                     /locus_tag="VIA51_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEQ8683156.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6134..6628)
                     /gene="rpsE"
                     /locus_tag="VIA51_001214"
     CDS             complement(6134..6628)
                     /gene="rpsE"
                     /locus_tag="VIA51_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEQ8683157.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6647..7003)
                     /gene="rplR"
                     /locus_tag="VIA51_001215"
     CDS             complement(6647..7003)
                     /gene="rplR"
                     /locus_tag="VIA51_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEQ8683158.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7108..7644)
                     /gene="rplF"
                     /locus_tag="VIA51_001216"
     CDS             complement(7108..7644)
                     /gene="rplF"
                     /locus_tag="VIA51_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEQ8683159.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7847..8245)
                     /gene="rpsH"
                     /locus_tag="VIA51_001217"
     CDS             complement(7847..8245)
                     /gene="rpsH"
                     /locus_tag="VIA51_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEQ8683160.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8396..8581)
                     /locus_tag="VIA51_001218"
     CDS             complement(8396..8581)
                     /locus_tag="VIA51_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEQ8683161.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8597..9139)
                     /gene="rplE"
                     /locus_tag="VIA51_001219"
     CDS             complement(8597..9139)
                     /gene="rplE"
                     /locus_tag="VIA51_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEQ8683162.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9163..9468)
                     /gene="rplX"
                     /locus_tag="VIA51_001220"
     CDS             complement(9163..9468)
                     /gene="rplX"
                     /locus_tag="VIA51_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEQ8683163.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRIGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9547..9915)
                     /gene="rplN"
                     /locus_tag="VIA51_001221"
     CDS             complement(9547..9915)
                     /gene="rplN"
                     /locus_tag="VIA51_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEQ8683164.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9940..10200)
                     /gene="rpsQ"
                     /locus_tag="VIA51_001222"
     CDS             complement(9940..10200)
                     /gene="rpsQ"
                     /locus_tag="VIA51_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEQ8683165.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10226..10432)
                     /locus_tag="VIA51_001223"
     CDS             complement(10226..10432)
                     /locus_tag="VIA51_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEQ8683166.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10442..10855)
                     /gene="rplP"
                     /locus_tag="VIA51_001224"
     CDS             complement(10442..10855)
                     /gene="rplP"
                     /locus_tag="VIA51_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEQ8683167.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10859..11512)
                     /gene="rpsC"
                     /locus_tag="VIA51_001225"
     CDS             complement(10859..11512)
                     /gene="rpsC"
                     /locus_tag="VIA51_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEQ8683168.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11525..11869)
                     /gene="rplV"
                     /locus_tag="VIA51_001226"
     CDS             complement(11525..11869)
                     /gene="rplV"
                     /locus_tag="VIA51_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEQ8683169.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11885..12163)
                     /gene="rpsS"
                     /locus_tag="VIA51_001227"
     CDS             complement(11885..12163)
                     /gene="rpsS"
                     /locus_tag="VIA51_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEQ8683170.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VIA51_001228"
     CDS             complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VIA51_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEQ8683171.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13153..13449)
                     /locus_tag="VIA51_001229"
     CDS             complement(13153..13449)
                     /locus_tag="VIA51_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEQ8683172.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VIA51_001230"
     CDS             complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VIA51_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEQ8683173.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VIA51_001231"
     CDS             complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VIA51_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEQ8683174.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILVKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14938..15246)
                     /gene="rpsJ"
                     /locus_tag="VIA51_001232"
     CDS             complement(14938..15246)
                     /gene="rpsJ"
                     /locus_tag="VIA51_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEQ8683175.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15447..16739)
                     /locus_tag="VIA51_001233"
     CDS             complement(15447..16739)
                     /locus_tag="VIA51_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEQ8683176.1"
                     /translation="MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSG
                     VSIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGL
                     LSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
                     VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRP
                     LDKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAM
                     ATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTD
                     AQRSAMIVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIG
                     VVWQYGLIGVWMATVLDNTSRWFILSKHFKKYQEITFH"
     gene            complement(17127..18143)
                     /gene="adhP"
                     /locus_tag="VIA51_001234"
     CDS             complement(17127..18143)
                     /gene="adhP"
                     /locus_tag="VIA51_001234"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEQ8683177.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18396..21038)
                     /gene="adhE"
                     /locus_tag="VIA51_001235"
                     /gene_synonym="adhC"
     CDS             complement(18396..21038)
                     /gene="adhE"
                     /locus_tag="VIA51_001235"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEQ8683178.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
BASE COUNT         6094 a         4473 c         3816 g         6776 t
ORIGIN      
        1 aattttgttg gaaacggctt aaagtgacag attttaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt agaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttgcgat gcaagttttt ttcggacatt taaacgaggg
      181 gattacaccg tttatttgcc catgagaggt ctttaaacac ctgcataagg ttttcttatt
      241 ctgatgacct tattgtctct gagaaaactt tataaacgca tcagaagagg cttctgtgtt
      301 attgttttgc tcagcttaaa agcggggggt gttcacctca taatacaaca aaacgcctgc
      361 ttataaaaag tttctatagc ttagatacct ttcataaaca agcgttacat attaacaata
      421 tgatgagtgt tcccgctagg aaaaatccta gcggtagacc agagctagac taagaataat
      481 ctctcgatta ctccatcatc ataacactca acaaaattga taaaaattaa actaattcaa
      541 taattgccat tggagcagca tctccacggc gtggttctgt tttaagaata cgagtgtatc
      601 caccgttacg ttctgcataa cgaggtgcaa tttctgagaa aagtttttga agagctgtcg
      661 ttgatgtgta tttatcggta gcttcatcat aattttctga tgcgatttcg ttacgaacgt
      721 atgcagctgc ttggcgacga gcatgaagat caccacgttt accaagagta atcatttttt
      781 caactgtttt acggatttct tttgcacgtg cttctgtcgt tacaattgat tcgttgatca
      841 aaagatctgt cgtcaaatca cgaagcattg ctttacgttg tgagctagtg cgtcctagtt
      901 tacggtaagc cattttgtcc tcctatatta tttatcgttt tttagtccga gacctaagtc
      961 agcaagttta accttaactt cttcaaggct cttacgtcca agattacgga ctttcatcat
     1021 ttcaggctca gatttttctg ttaaatcgaa gacagtgtta atgcctgcac gttttaaaca
     1081 gttatatgag cgtacggata aatcaagctc ctcgatggtg cggtcaagta ccttttcatc
     1141 gttcactttt tcagtttctt tcattacttc ggtagctttt gcaacctctg ttaaatcagt
     1201 aaacaggttt aagtgttcga tcaaaactcg agcagataga cctaaagcat cttcaggaat
     1261 aattgttccg tttgtcatga tttcaatcgt taatttatca aagccatcat tgctacctac
     1321 acgggcaggt tcaacttgat aattaacttt tttaactggc gtatagattg aatctactgc
     1381 caatgtaccc acaggtgcat catctttttt gttgccttct gctggcacat aaccacgttt
     1441 tttagcaaca gtcattgttg cacgtagaga atgtccttca gcgattgtaa aaagataatg
     1501 atccgggtta acaagttcga tatcactgtc agtaagaata tcaccagctg ttacctctgc
     1561 tggtccttct acttcaagtt cgataatctt ttcgtcttcg acgtatgatt tcacagcaag
     1621 tcccttaaca ttaaggataa tttgcatgac atcttcacgt acacctggga ttgtatcaaa
     1681 ttcgtgtagt actccatcaa ttttaattga tgttactgct gcacctggaa gtgaagacaa
     1741 gagtacacga cgaagagaat tacctagagt tgttccgtag ccacgttcaa gtggttcgat
     1801 gacaaatcta ccgtaatctt tattttcatc aatttttgtt attattggtt tttcaaactc
     1861 aatcattttt tcacccctcg aaacgaaact tgtgtactat ttgttatatg attatacacg
     1921 acgacgtttt ggaggacgag caccattatg tggcacaggg gtcacatcac gaattgcagt
     1981 tacttcaaga cctgcagctg ctagagcacg aatagctgat tcacgacctg aaccaggacc
     2041 ttttacagtc acttcaacag tttttagtcc gtgttcttgt gcagattttg cagcagcttc
     2101 tgcagccatt tgagcagcaa atggagtaga tttacgagaa cctttgaaac caagagcacc
     2161 agctgatgac catgcaagag cattaccatg cacatctgta atcataacaa tagtgttatt
     2221 aaatgtagcg tgaatgtgtg caacaccaga ttcgatgtcc tttttcacac gacgtttacg
     2281 tgttggttta gccaattgtt ttacctccta ttttattttt tcttacctgc aatcgcaaca
     2341 gctttccctt tacgagtgcg agcattgttt ttagtatttt gtccacggac aggaagtcca
     2401 cgacgatgac ggattccacg gtatgaaccg atttccatca aacgtttaat gttcatgttt
     2461 acttcacgtc gaaggtcacc ttcaactttg attgcatcca cttcacgacg gatagcatct
     2521 tcttgatctg atgttaaatc tttaacacgg atatcttcag aaatacctgc agctgctaag
     2581 atttttttag atgttgcaag accaattccg taaacataag taagtgaaat tactacgcgt
     2641 ttatcatttg gaatatcaac tccagcaata cgagccattt tttctccttt ctattttatc
     2701 cttgacgttg tttgtgtttt ggatttgtcg gacaaattac cataacacga ccattacggc
     2761 gaataacttt acagtattcg caaattggtt taaccgatgg tcttaccttc atgttttaat
     2821 ccctccaatt atttcgatta tttaaagcgg tatgtgatgc gtccacgtgt caagtcataa
     2881 ggactcattt ctactgtaac acggtcacct actaaaatac gaatgtaatt tttgcggatt
     2941 tttcctgata cagttgctag aatttgatgt ccattttcca attcaacagt aaacattgca
     3001 tttggcatcg tttctactac tttgccttca atttcaatca cgtcttcttt tgccacgcaa
     3061 aagtaccccc taaatttcga tttgatgtcc tctgagcaca gaggtaacaa ttataagtca
     3121 gactaaacta gtatatcatt actaatctac ttatgcaagt agatttgtat aatttatttg
     3181 agttctagca acgctttttc aacatctgca aaaacgtctg ttatttcttg attaccttca
     3241 atatctgtaa caagaccaag cttacgatag tgttcaagaa taggttctcc ttgagccata
     3301 ttgacgtcca aacgacgttt aacagtttca ggcttatcat cttcacgttg atagtaatct
     3361 tcttctttat aatctactgg tgggttgaac actttatgga acgtttcacc agttttacga
     3421 ttgataatac gaccactcaa acgctctaca agacatgatg gatccacttt aatattaata
     3481 acaccatcta agcggagtcc tagttcttca agtgttgcat ctaaggcgtg tgcttgttca
     3541 atagtacgtg gatacccatc aagcaaaaaa cctttttctg cgatatcatc ctcagctaag
     3601 cgctctttta caatcccgtt tgtgacttca tcaggaacca attcaccttt atcaatataa
     3661 cttttagcta aacgtcccat ttcggtttga ttagccattg cggcgcggaa catatcccct
     3721 gttgagatgt gagcaatacc aaattcttca acaatcttag ctgcttgggt ccctttacca
     3781 gctcccggca aacccatgat taaaagattc atcttttcct cctcttttaa aataaataca
     3841 tagtaggaaa ttattttcct tggtttttgt tttcaaatgg caacaagaaa tcgtttgatg
     3901 ataaccaagt cttattgtca tttaaaaaca aaatagaagg ttgacaatgt caacctgtat
     3961 tctattctgc tgtattcata aatccgacat attttctctt tagaagatat ccctcaagct
     4021 gtttcatacc ttcgatacca gttgaaatca aaatgagcaa actagttcca cctaaagcaa
     4081 tactagaaga aaggttgaga gcttgttgtg ctgctattgg cgctaaagag ataaatgcta
     4141 agaagatagc tcctacggtt gctagttttt ttagcaatgc ggacataaat tgttctgtct
     4201 cacgtccagg gcgaacactt ggtatatatg aggaattctt ctgaagattt tctgctgtct
     4261 tctcaggatt aacttgtaca aaggtataga agaatgagaa caatataatc aacaaggcgt
     4321 aaactatcat tccgactgga gtttgataat taaaaatttc ttgcaaacgg tttaaccacg
     4381 gtaaatctct accattttga acaaaaggaa taatcgtact tgggatagtt gtaatcgagc
     4441 tagcaaagat aacgggaata acgccggctg gatttacttt taatggaaga tatgaacttg
     4501 taggtgcacc ttgcattagc tttgtgtatt ggattggaat tttatattcc gcttgttgga
     4561 catatgttgt aaagaaaaca atagcaagaa cagctatgat taaaatccca acaatgagat
     4621 aagacgagtg taaatcactt gccttaacat ttacaaaata gtcttcacga attgttgcaa
     4681 ttgcacttgg aatagacgaa ataatacccg caaagataat cattgatacg ccattaccaa
     4741 atcctttatc tgtgatttgt tctccaagcc aggtaacaat aacgctacct gttgtcagta
     4801 atgccccgat cagtaaatat gttttgatgt ctggtgtctt aacaagtgca acgttcgaca
     4861 aagtattaaa ccctgcagtg ataccaatgg attgggcaaa agccaaaaca agtgaaatat
     4921 agcgcgtcgc ttgatttaat ttacgacgtc caacctcacc ttgtttgccc cactcaacaa
     4981 acttaggtaa aatatccatc tgcaataact gaacaacgat agaagcagta atatatgggc
     5041 taacccccat tgaaaatact gagaaatttc tcatcgcatt accactaact aagtttaaca
     5101 tatttaagaa agggagttca cttaattgct ctaagctctt ggcatttaca ccaggtacgg
     5161 taatatgtgt cccaattcgg aatacaagaa tgataaatat agtaaagaaa attttattcc
     5221 gtacagtctt tatctttaac gcgtctttta gtatttttaa gaacataatg agtatcccct
     5281 cattagatga cttcgattga accaccttta gcaataatag ctgcttcagc agattttgag
     5341 aacttagctg cttttacagt caatttttta gtcaattcac cgttaccaag cactttaacg
     5401 cctgattttt cagctcggac aataccagca tcttttaaaa tagccggagt cacttctgta
     5461 ccatcatcaa aaacattcag ttgatcaaga ttcacaagtg catattcttt agtattaata
     5521 tttgtaaagc cacgttttgg aatacgacgg aacaatggtg tttgtccacc ttcaaaacct
     5581 aaacgtacac cgccaccgct acgagctttt tgaccttttt gaccgcgacc agatgtttta
     5641 ccattacctg atgatgtccc acgaccaaca cggttacgta ctttacgtga gccttcagca
     5701 gcttttaatt catgaagttt cattttttct cctttttttg taaaatgcta gcgcctctat
     5761 gagggaaaag gactccctat agaaactcgc ctatacatta atgatactta agttatccaa
     5821 aataacttaa tacagatacg cactaaccga ctactgtttg ttgccaaaaa gcaaactaca
     5881 agagtcggtt ttgtgctcgt ttttaattat gaaatcagag atttcacagt tataacttat
     5941 ttaacatctt caacggtaac caagtgagaa atagctgtca ccataccacg gatagcagca
     6001 ttatcttctt tgactactga agagtttaat ttaccaagtc caagagcaac aacagtttta
     6061 cgttgttctg gcttacgtcc gataggagac ttagtcaaag taattttaat ttgagccatg
     6121 atgatcccct ttcttatgct aagtcagaaa ctgagatgcc acgaagtgcg gcaacttctt
     6181 ctgcacgttt aagttgtttc aatccttcaa cagttgcacg aacaatgttg attggagtgt
     6241 ttgaaccaag agattttgaa gtaatatcag caacacctgc taattcgatg acggcacgaa
     6301 ctgcaccacc agcagcaact ccagaacctt ctacagctgg tttcaataat actttagctc
     6361 caccgaagtt agtgtaaact tcgtgaggga ttgttgtacc aaccattggt acttcgatca
     6421 tgtttttctt agcagcttca actgctttac ggatagcttc tggaacttct tgagctttac
     6481 cagtaccaaa tccaacacga ccatttccat caccaacaac tacaagagct gcaaagcgaa
     6541 gacgacgtcc acctttaaca acttttgtaa cgcggttaat cgcaacaacg cgttcttcaa
     6601 gttcaactgc attatcttta aatgccattt ttttgtgtcc tccctattag aatttcaatc
     6661 cgttttcacg agctgcatca gccaaggctt taacacgtcc gtgatagaga tatccaccgc
     6721 ggtcaaacac cacttcagaa atacctttag ccactgcacg ttcagcaaca agtttgccga
     6781 ctacaacggc ttgttctgtt tttgttcctt tagaaacgtc tttatcaaga gttgatgcac
     6841 ttgcgagcgt tacacccgct acgtcatcaa taacttgagc gtagatgcct gtattagaac
     6901 ggaatacgtt caaacgtggg cgatcagcag ttccagagag tttaccgcgg acgcgacggt
     6961 ggcgtttttg gcggattttg tttttatctg gtttcgaaat cacaattttc acctcttaat
     7021 tttaatcaat ttgtctcatt gacaagttgt cgattgaact tatcgagcat gttaaggtgc
     7081 aatacttccc atacccgact aagaacatta tttacctgtt ttaccttctt taaggcgtac
     7141 gtattcacca acgtaacgga tccctttgcc tttgtaaggc tctggtgaac gcaagctacg
     7201 gatgtaagca gctgtttgac caacaacttc tttgttgatt ccttcaactg agattgaagt
     7261 tgggttagca acagtgaaag taattccttc tggagcttca acttcgtctt ggtgagattt
     7321 acctactgaa aggacaagtt tagtaccttg aagttgagca cggtaaccga cacccttcat
     7381 ttcaagatct tttttgaaac cttcagaaac acctacaacc atgttattca agttagcacg
     7441 ggttgtacca tggattgttt tcatttcttt tgagtcgtta ggacgtacaa ctgtgatttc
     7501 agtcccttca actttgattt caatattttt gttgaactca cgagtgagtt cgcctttagg
     7561 gcctttaaca gtaataacat tgttgttatt tgttaattca acgcctgcag gcatagtaat
     7621 tactttatta ccaatacgtg acatgtttat tttctcctgt taaattgtca agccgcatag
     7681 cgactagttt tcacgggggt ttgatagaat gatatacttc aatttatatt tcaaaattga
     7741 acacgagctg tggtctgtgt gaaaaagata aatcttcctt gagtgtaaac acgctacgtc
     7801 agatttccta ttttcacttt gtccacgacg ctcttagtat cttaaattac caaacgtaag
     7861 cgatcacttc tccaccaaca ttcttttggc gagcttcttt gtcagtcaaa agaccttctg
     7921 atgttgaaat gattgcaatt ccaagtccgt taagaacttt aggcatgtca tcacgttttg
     7981 cgtaaacgcg aagacctggt tttgaaatac gttttaagtt agtgataaca cgttcaccat
     8041 tttttccgta ttttaagaac acacgaatga tgccttgttt atcatcttcg ataacttcaa
     8101 cattttttac aaaaccttca cgtttaagaa tctcagcaat ccctttttta atgtttgaag
     8161 caggtacttc taacacttcg tgttttactt gattagcatt acggatacgt gttaaaaagt
     8221 ctgcaattgg gtcagtcata accatttttt atattctcct cttactagca gtttgatgct
     8281 atcacttact agttaatgtt gtccttaaag gactttggta tcagcttatg ctcacaccgt
     8341 tttaattaag cacaagactt aatctgaaga acaaattaag ttttgtgtca tatttttacc
     8401 aagaagcttt gacaacacct ggaatttgac ctttgtaagc caattcacgg aagcaaacac
     8461 gacaaagttt aaacttgcgg taaactgaat gtggacgtcc acatttttca cagcgagtat
     8521 aagcttgtgt agagtgtttt gcaggacgtt tgttcttagc aatcatagat tttttagcca
     8581 atttatttac cccctattat tttgcaaaag gcattccaag gcccttaagc aattcacgtg
     8641 attcttcgtc agtatttgca gtagtgacga ttacaatatc aagaccacgt actttatcaa
     8701 catcatcaaa gctgatttct gggaagataa gttgttcttt cacaccgaga gtgtagtttc
     8761 cgcgtccatc aaacgatttt gttggaacgc catggaagtc acgtacacga ggaagtgaaa
     8821 cgctaaccaa tttgtctagg aattcgtaca tacgttcgcc acggagggta acttttgcac
     8881 cgatcgctac accttcacga agacggaagc cagcgattga tttcttagct ttagtaataa
     8941 gtggtttttg acctgagata agtgctaatt cagctgcagc tttctctagg ttttttgcgt
     9001 tggatacagc atcaccaaca cccatattga gaacaatttt ctcaactttt ggcacagcca
     9061 taactgatgt gtaattgaat ttctctgtca acgcaggaat tacttcgtta gtatattttt
     9121 cttttaaacg atttgccatt atgcttctcc tttccttcgt gattaatcaa gcacttcgcc
     9181 tgattttttg ctgtaacgta cttttttacc gtcaacaact ttataaccaa tacgtccagc
     9241 tacaccattt ttatctaata cttgaacatt agagacatgg ataggtgctt ctttttcgac
     9301 gatagctcct tgaggatttt cagtgttagg tttttggtgt tttttaatca ttccaacacc
     9361 ttcaacaata actttgttaa cttttggaag tgctttaaga actacagctt cagtgccttt
     9421 gtccttgcca gcaattacgc gaactttgtc gccttttttt acaaacattc tggtttctcc
     9481 tattatttct tacgccccga tgggcaccct aggaaaacct aggggactac gtttgttaat
     9541 ctgagattaa agtacttctg gtgcaagtga tacgatcttc atgtagccac cctcacgcaa
     9601 ttcgcgtgca actgggccaa agatacgagt tccgcgagga gttttatcat cacggatgat
     9661 tacagcagca ttgtcgtcaa atttgatgta tgaaccgtct ggacggcgtg caccagtttt
     9721 tgtacgaacg ataacagctt taaccacatc acctttttta actgctccac caggagtagc
     9781 ttgttttaca gaagcaacga ttacgtcacc gatgttagcg aatttacgtc ctgaaccacc
     9841 aagtactttg atagtcaaga tctcacgagc accgctatta tcagcaactt tcaagcgagt
     9901 ttcttgttga atcatttcaa ttttctcctt ttagtttgat tagataataa cagctttttc
     9961 cactacttcc acaagacgga aacgttttgt agctgaaagt gggcgagttt ccatgatacg
    10021 aacgatatcg ccttctttag caacgttgtt ttcgtcatgt gctttatatt ttttagaata
    10081 gttgatacgt ttaccataga ctgggtggtt acgtttagtt tcaactacaa ctgtgattgt
    10141 tttgtccatc ttgtcagaca ctacgcgtcc gtaaagagtt ttacgttgat tacgttccat
    10201 ttagaatttc tcctttccca atctattatt tcatttctga ttgcacagtt ttaacacgtg
    10261 caatttgttt cttaacttcg tcaaggcgag cagtcttttc aagttgacct gctgcagctt
    10321 ggaaacgaag atcaaacaat tcttttttga gttcgttttc tttcttagca agttcttctt
    10381 gagacaatcc acgaagctct ttaacaaaat ctttaatttc ttgaagtttc atgtcttctc
    10441 cttattctgc ttcacgtttt acgaatttgc acttaactgg taatttgtgg ctagcaagac
    10501 gtaatgcttc gcgagcaatt tcttcagaaa caccagcaat ttcaaacatc actttaccac
    10561 gtttaactgg tgctacccaa ccttcaggtg cccctttacc agaacccata cgtacaccga
    10621 tagcttttgc agtgtatgat ttgtgtggga agattttaat ccaaacttta ccaccacgtt
    10681 tcatgtaacg agtcatcgca atacgggcag cttcgatttg acggtttgta atccagtggc
    10741 tagttgtggc ttgaagtccg tattcaccga atgaaacttc tttaccacct ttagcctcac
    10801 cgcgcatttt tccacggaat tcgcgacggt gtttaacacg tttaggtact aacatttgtt
    10861 atttgcctcc tttagtgttt ttacgagctg gaagaacttc tccacggtaa atccaaactt
    10921 taacgccaag tttaccataa gttgtgtcag cttcttccca agcatagtcg atatcagcgc
    10981 gaagcgtgtg aagtggaaca gttccttctg aataaccttc agcacgagcg atatcagcac
    11041 cgttcaaacg accagaaact tgagttttaa tccctttagc tcctgcacgc attgtacgtt
    11101 ggattgcttg tttttgagca cgacggaaag caacacgttg ctcaagttga cgagcaatgt
    11161 tttcaccaac aaggtgagca tctaaatcag gttgtttgat ttcgatgatg ttgatgtgta
    11221 cttgttttcc agttaatttg ttaagttgac cacgaagagc gtcaacgttt gcgccacctt
    11281 taccgataac catacctggt ttagcagtgt gaagtgaaac aataactttg tttactgcac
    11341 gttcaatttc aatagttgaa actgatgcgt cagctaattc tttattaatg aatttacgga
    11401 ttgcaagatc ttcatgaagg taatccgcgt attctttttc agcataccat ttcgcatccc
    11461 agtcacggat gattccgaca cgcataccaa ttggatgtac tttttgaccc acgattttac
    11521 ctccttattt ttctgataca actacagtta cgtgagttgt acgtttgttg attggtgaag
    11581 ctgaaccttt cgcacgtgga cggaaacgtt tcattgttgg tccttcgtta gcgaatgttt
    11641 cagatactac caagtttgct ttttccaaac caaagttgtt ttctgcgtta gcaattgctg
    11701 agttaagagt tttctcaata acacgagctg ctttgtttgg agtgaatttt aagattgcga
    11761 ttgcgtcagc aactttctta ccacggataa gatcaagtac taaacgtgtt ttacgaggtg
    11821 aaacacgcac tgtacgagcc attgctttag ctgaagtaat ttctgccatt gtgtcctcct
    11881 cctattaacg acgtgttttc ttgtcgtcag ctgcgtgacc tttgtaagta cgcgttggtg
    11941 caaattcacc aagtttgtga cctaccatgt cttcttggat gtaaacaggt acatgtttac
    12001 gtccgtcata aactgcgatt gtatatccga tgaaacttgg gaaaatcgtt gaacgacgtg
    12061 accaagtttt gattactttt ttcttttcgt cgtttgcttg agcttcaact tttttcatca
    12121 aatgctcatc gacgaaaggt ccttttttaa gactacgtcc cattttgtag ttttctcctt
    12181 taaataatgt accacagcgg cttgaattca agagcaagac tccaaactct accgagttgg
    12241 cggaataaat agcaaagcta ttgtaacgct atttcagcaa gtttttagca acttactaaa
    12301 attatttttc gttacgacga cgaacgataa gtttgtctga tttagctttc ttgttacgag
    12361 ttttaagacc aagcgctggt ttaccccatg gagttgatgg cgctttacgt ccaactggtg
    12421 ctttaccttc accaccaccg tgtgggtgat cgttagggtt cattacagaa ccacgaactg
    12481 ttgggcggat acctttccaa cggctacgtc ctgctttacc aatgttaaca agtgattgtt
    12541 gttcgttacc aacagtaccg atagttgcac ggcatgtacc aagaatcata cgaacttcgc
    12601 ctgattgaag acgaacaaga acgtatttac cttcttgacc aagtacttga gcagaagctc
    12661 cagctgcacg aacaagttct ccacctttac caggtttcaa ctcaatattg tgaacaactg
    12721 taccgacagg aatgtttgct aatggaagtg cgttaccaac tttgatatct gcatctggac
    12781 cagaaacaat acgttgacct acttcaagac ctttaggtgc aatgatgtaa gctttcacac
    12841 cgtcagtgta atgtacaagt gcgatgtttg cagtacggtt tggatcgtat tcgattgttt
    12901 taacaactgc ttcaacgcca tctttgttac gtttgaagtc gatcaaacgg taatgacgtt
    12961 tgtgtccacc accttggtga cgaactgtga tgcgaccatt gttgttacga ccagctttgc
    13021 tcttaagaga aacaagcaat gatttctcag gcgtgcttgt tgtgatttcc gcgaaatcca
    13081 aagaagtcat gttacgacgg ccatttgtcg ttggtttata aactttaata cccacgttat
    13141 ttcctcctta gattattcag cttcagctgc gaacaactcg attgctttag aatcagctgt
    13201 aagagtgatg atagcttttt tagtttttga agtgaaacct gtgtaacgac caacgcgttt
    13261 tgcttttggt ttaacgttaa cagtgtttac acttgcaact ttaactccgt caaaagcagc
    13321 ttcaacagct tgtttgatca aaagtttgtg tgcacgagta tcaacttcga aagtgtattt
    13381 gcctgcttca agagcaatca ttgacttctc agtgataact ggttttttga ttacgtcgta
    13441 caaattcatt atgcaagaac ctcctcaatt gtagagattg cttctttagt aacaagaagt
    13501 ttgtctgcgt tcacgatatc aagaacactt gcagttgctg cagttgcaac agttacgttt
    13561 ggaaggttac gtgcagaaag tgctgcaaat tcatttcctt cttcaacaag aacaagtact
    13621 tttgtatcaa tgctaagagc tgaaagcact tttgcaaatt cagcagtttt tggtgctgca
    13681 aatgaaaggc cttctacagc tacaaattta tcttcagcaa cttttgctga gtaaactgat
    13741 ttcaacgcaa ggcgacgaac tttttgtgga agtttgtatc cgtatgaacg gggagttggt
    13801 ccaaagacaa caccaccacc acgccattgt ggtgagcgga tagaaccttg acgagcgcgt
    13861 ccagttcctt tttgacgcca tggtttacgt ccaccacctg atactgctga acggttttta
    13921 accgcatgag taccttggcg aaggctagcg cgttggctaa ttacaacatc aaaaacaact
    13981 gattcgtttg gttcgatacc gaagatagcg tcgtttaatt caactgagct aacttcttta
    14041 ccagtttggt caaatagttt tacgtttgcc attttaactg ttttctcctt tcttattatt
    14101 tagcagcttt aactgctgac ttgatagtga taagagattt cttagcacct ggtacgttac
    14161 ctttaacaag gataacgttc ttttctggga taacttgtac aatttcaagg ttttgaactg
    14221 ttacacggtt accacccata cgtcctgcca agcgtttgtt tttgaaaacg cggttaggcg
    14281 caacaggtcc catagaacct gggcgacgat ggtaacgaga accgtgagcc ataggaccac
    14341 gtgattgacc atggcgtttg ataacacctt ggaaaccttt accttttgat gtccctgtga
    14401 cgtcaacaac atcaccagct tcaaattgtt ctacagataa ttctgcacca acttctaagc
    14461 cttcaatgtt tttgaattca cgaatgaagc gcttaggagc tgtgtttgct tttgcaacat
    14521 ggcctttggc aggtttgtta ctcaagactt cacgtttgtc atcaaaacca acctgaactg
    14581 cttcataacc gtctgtttca acagttttaa cttgaagcac aacgtttgga gttgcttcaa
    14641 tgacagtaac agggatgaat tcgcctgatt cagtgaagat ttgagtcatt cccacttttt
    14701 tccctaagat tccttttgtc atgagaaaat atttcctttt cttaataata tttcaaaaag
    14761 ttttttacga gcgttttttg tgctcatagc aagatacaaa gagcgtcaaa ctcaaaataa
    14821 aaatagaaaa tctaacacaa aagcttctgt ttcgaggaag atttatcttt ttcatgtaga
    14881 gtttagctcg tgttcaagtt ccatcaaaca ctaactgtac ttgcaaaatc tcaccgatta
    14941 aagtttgatt tctacgttga caccacttgg aagatcaagt ttcatcaaag catcaacagt
    15001 tttttgtgtt ggattgatga tgtctaccaa acgtttgtgt gtacgcattt caaattgttc
    15061 gcgagaatct ttgtatttgt gagtcgcacg aataattgtg taaagactgc gttcagttgg
    15121 aagtggaact ggtccagcaa ctgtagcacc tgtacgtgtt gcagtttcaa cgattttttc
    15181 tgccgctgta tcaagtgtac ggtgttcgta cgctttcaaa cggatacgga tttttttgtt
    15241 tgccatcttt tctcctctcg tctatttacg ataataggct agctcctcaa gaaaaccgac
    15301 acctgttgcg tggcaatgca accgagcgtg tcgcaacctc ttgtatcatt gctaaagctg
    15361 tatttttaca gcaccacaat ataataacag aatcatttag tcattgcaag ctttttaggc
    15421 atttttttca aaaaaaaact accttcctaa tgaaaggtaa tttcttggta ctttttaaag
    15481 tgtttagaga gaataaacca ccgactggta ttatctaaca ctgtcgccat ccagacccct
    15541 atgagtccat attgccaaac cacaccaatc acataaccaa ggccaatgcg aatcacccac
    15601 attcctatgg ttgttgcata gaaaggaagc tttgcttttc ccaaaccctg ccagacggct
    15661 gtataaacta aagtgcctgc cgttgcggga gctcctagta aagaaaaaag taaaacaatc
    15721 atggcagacc tttgagcatc agtattctgt gtaaatagcg gcaagagact aggacctagc
    15781 agataggtca aggctcccat aaccagcatc atgagggtgg ataaaataaa agcttctcta
    15841 ataatatacc ttatctcagt caccttaccg ccccccagtt gcctagccac tagaataatt
    15901 gttgccgttg ccatggctaa gccaggcatg taattaaact gagtcaaggt ttctccaata
    15961 gcattacctg ccaaggccgt tgtcccaaag cgaacaacaa tgccaataat taggacatct
    16021 cctgctctca tcatcaaacg ttcaccagca gcaggtagtg ataaatcaaa aataattttg
    16081 tccaaaggtc tcatcaatcg tttcgcaacc tgtttaatag gaataaactg acaaagtaaa
    16141 aacacaccca ctaaacgaga taaaaccgtc gcccaagcaa caccaagaag accaaatccc
    16201 catacataga tagacaaggc agaaaaaatg gcattgagta cgtttattaa taagctcact
    16261 tgcataggaa tcttaggata cccttgagct cgaacaatag ctcctaagct agttaaaagt
    16321 cctagactaa caatcatacc gccgacaatg gatagatatt gccctccaac caatgttaca
    16381 gaagcttcag ctcctagcca ttctaacacc tgatgatgtc cagcaactga taacaaccct
    16441 aagccgaccg aaaggaggag tgttacttgc aagacacctg ccatatagtt taattgtttg
    16501 ttctgattat tttctccaat acttcgagca atcagactag atacagcagc tcccagcgcg
    16561 ataaagaggg actgataaat actgataatg ttgttagcta tggagacacc agagactgct
    16621 acaagtccaa tttgagccac caggtaatta tcaaccattc ccattaacat ctgtaaaata
    16681 ttttctatca tagaaggcag agctaaagag aaaatttttc ttctattatt atatatcatt
    16741 tatgtcccct aataaaaaat tcttgatcaa acgatttttt caaacacagt cactggactc
    16801 attcagttat tttggtccat taatgaattc ataaagtcta tcttaatagc agagtcccaa
    16861 gatacacgac acttagtgtt acagtaacaa ttgaccacat gccaatcctt aacatttacc
    16921 taacgtttat aactaagaag atgaagaaca aaaggactcc aaacgaattt tttctattat
    16981 ataatatatt cttcatttag caactttcaa tgtatcaaaa tagcactctc gagtcaaaaa
    17041 tgttttctga tactcgagag tgctatttta tttggaatca agtttaagca acttaggctt
    17101 atctcatatt taatacattt gtatgtttag ctgatgaaat ctaagacctt gcgcccttgg
    17161 attaaaccac gttccatttc atcaaagact tctggagcag tgtcaactgg aactttttcg
    17221 acaaccggag caaccagacc ttctgcacca aaggcaaagg cttcttccaa gtctttacgt
    17281 gtccctacaa gtgatccgac cactttgata ccatctaaaa cagtttttac gatagacagt
    17341 tccatgtatt ctgatggaag acctacggct acaactgttc caccggcacg gacactatca
    17401 attgcttggt taaaagcaac tttagaaaca gccgttacca caacaccatg tgctccaccg
    17461 gttttttctt gaatatagcc tggaacatct tcaatttctt tgccgttaac taaaatatct
    17521 gcgccaactt ctttagctaa ctcaagttta tcattattaa tgtccactgc gacaacatgt
    17581 gcattaaaga cttttttagc gtattgaaca gccagatttc caaggccacc agccccaaag
    17641 ataacaatcc attggcctgg agcagcacct gcctctttaa tagctttata agttgttaca
    17701 ccagcacaag taatggaaga agcttgagcc gggtctaaac cttctggaac tttaactgca
    17761 taatcagctg ttactactgc atattcactc attcctccat caacactgta tccagcattt
    17821 ttaacactac gacaaagtgt ctcacgtcct gtagtacagt attcgcaatg accacatcct
    17881 tcaaagaacc atgcaataga gacacgatca ccaaccttta aggatgttac gccttctcca
    17941 atttcttcta ctataccaat accttcgtgc cccaaaatac gtcctggtac ctgaccaaaa
    18001 tcgccatgtg caacgtgtaa atcagtatga caaacgccac agtattctac tttaacaagc
    18061 gcttcaccat gaccaatatt tggaagatca tgctcaacaa cttcgacacc tgtactagct
    18121 tgattaacaa ctacggcttt catatcagtc ctccatctaa taatgacttt ttttgtaatc
    18181 ggttacaaat aaattgtaca tcttttcaca atgaaagtca atagaaacct gaaaagtttc
    18241 tgaaacttaa ctggttaatc ttatagctgt ttgcctatct gcaaaatact taactacatt
    18301 ttctgacact ggatataaat gatatattta gaaaataaaa tgatttctta tgactttaat
    18361 cataagaaat catttcctgg tatcaacatt aaaaatcact tacgtcgtcc tggacgttca
    18421 gcataaccat agtaagcatc ttcaataatt tcttgcatgt gatcaaccat tggaagacgt
    18481 gggttagcag gtgaacattg gtcttcataa gcaaggtaag ccaattcacg agaatgttct
    18541 ttccattcgt tttcgtcgat accttgagct ttgaagttca tttgaatacc aactcggcaa
    18601 cccagatcat aaacagcttt cgcataagat tccactgctt cttctggtgt agaagctgga
    18661 agccctaaca atttcgcaat gtcttggtat ttttcatccg cacggtagta attatactta
    18721 ggccatgtcg ccgttttagc tggacgagtc ccattatagc ggataacata cggcaaaaga
    18781 attgcatttg tacgtccgtg tacggtatgg aattgtgcgc caattttatg cgccattgag
    18841 tgagaaatac ctaagaatgc attggcgaaa gccatacctg ccatagttga cgcattatgc
    18901 atcttttcac gtgcttcaaa atcggctgtt ttaactgatt tttcaagatt atcaaaaaca
    18961 attttaatgg cttgaagagc taaaccatcc gtaaagtcat tggccatttg tgacacgtaa
    19021 gcttcggttg cgtgtgtcaa aacgtccata ccagtatcag cagcaataaa gcctggaaca
    19081 gtcaatacca aagctgggtc aacaatggct acagttggtg ttaatgagta atcagcgatt
    19141 ggatatttac gattatttgc tttgtcagag ataacggcaa atggtgtcac ctctgaacct
    19201 gttccagaag ttgttgggat agcaacaaat tttgttttct taccaagttc tgggaatttg
    19261 aacgcacgtt tgcggatatc catgaatttt tgaacgaggt catggaaatc aacttctggt
    19321 tgctcgtaga agagccacat aactttggct gcatccatag gggatccccc gccaagggca
    19381 ataatggtgt ctggtttgaa ggtacgcatt aattcagtac ctttcataac agttgtaatg
    19441 tctggatctg gttctacttc agcaaagatc tgataaacaa ctttattgcg acgaagatca
    19501 agttgttcaa tgatacgatc caagaaacca agctcaacca tagcgtgatc tgtaacaatc
    19561 atgacacgtt caacgtcacg acatttttgc aaatattgaa ttgaatcacg ttcgaagtat
    19621 gtttttgaag gaactttaaa ccattgcata ttatttctac gtcttcctac ttttttgatg
    19681 ttcaagagat ttatagcact aacgttatca ccaactgcgt tacgtccata cgaaccacaa
    19741 ccaagagtca atgatggtaa gaaagcattg taaacatccc cgataccacc aaatgtagaa
    19801 ggtgaattcc agatgacgcg gatagcacgg attctagttc caaattcttt tgccaattct
    19861 gcatctgctg tatgaatggc agctgagtga ccgagtccat taaattcaac catttgacga
    19921 gctttttcaa caccgtcttc acgtgattca gattttaaaa cagcaatgac tggagataat
    19981 ttttcacgtg ttaaaggctc attttctgaa acttctttac attctgcagc aagaatattg
    20041 gttccttctg gaacagtaaa tccagcttgt tctgcaatcc aagtagctgg ttttcctaca
    20101 atatttggat ttaattttgc accagcacag tttttgctat ttgctttggc accaaaacag
    20161 aattcttcaa gaagggcttt ttctttttta tttacaaaat aagtatggta agatttgaat
    20221 tctgctacaa aatcgtcata gatttcttta tcgatgataa cagcttgttc agaggcacag
    20281 accataccat tatcaaatga tttagacatc acaatatcat gagcggcttg acggatatta
    20341 gctgattttt caacataagc tggaacgtta ccagcaccta ccccaagggc aggtttccca
    20401 catgagtatg ccgctttaac catcgcattt ccacctgtcg caaggatagt ggcaatgccg
    20461 tcatgattca tcaaagcatt tgttgcttca agtgatggtg tttcaaccca ctgcacacaa
    20521 ttttcaggag caccagcggc aatagcagca tcacgaacaa tacgagcggc atgtgctgat
    20581 gattcttgtg ctgatgggtg aaaggcaaaa ataattggat tacgtgtttt taacgaaatc
    20641 aaagatttaa agatagctgt tgaagttggg ttagttgttg gtgtaatccc acagataaca
    20701 cccaccggct cagcaattaa tgtcaaacct gtcacatcat cttcttcaat aattcctact
    20761 gttttttgat ggcgcatgtt attaaccaca tgctcacaag caaatagatt ttttgttgct
    20821 ttatcttcaa agacaccgcg acctgtttct tcataagcat gtttagcaag ttcaccgtga
    20881 gcatccaaag cagcaacaga agctttggct acgatataat caacttgttc ttggtcaagc
    20941 ttacgcatct cttcaagagc agctaaacct ttttgaacaa gagcatcaat tgtcacagaa
    21001 acagaggttg tttcaacagt attatgtcct tcagtcattt gagactcctt tatattgtta
    21061 aaagtttcac aattttgttt acaaaattat tatagcactt tttgaaattt tgtaaatcat
    21121 ttcacaataa atttgtgaag tttttttcaa attatttct
//
LOCUS       DAUGQX010000033        20378 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUGQX010000033 DAUGQX010000000
VERSION     DAUGQX010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20378
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.033"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            471..860
                     /locus_tag="VIA51_001236"
     CDS             471..860
                     /locus_tag="VIA51_001236"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEQ8683179.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            954..2006
                     /locus_tag="VIA51_001237"
     CDS             954..2006
                     /locus_tag="VIA51_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8683180.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2145..3677
                     /locus_tag="VIA51_001238"
     CDS             2145..3677
                     /locus_tag="VIA51_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683181.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGVPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVSPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3670..4734
                     /locus_tag="VIA51_001239"
     CDS             3670..4734
                     /locus_tag="VIA51_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683182.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4736..5692
                     /locus_tag="VIA51_001240"
     CDS             4736..5692
                     /locus_tag="VIA51_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683183.1"
                     /translation="MSLVTIFALLMSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5905..7623)
                     /locus_tag="VIA51_001241"
     CDS             complement(5905..7623)
                     /locus_tag="VIA51_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8683184.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDENKSSGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVEADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7799..8368)
                     /locus_tag="VIA51_001242"
     CDS             complement(7799..8368)
                     /locus_tag="VIA51_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8683185.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8426..8971)
                     /gene="coaC"
                     /locus_tag="VIA51_001243"
     CDS             complement(8426..8971)
                     /gene="coaC"
                     /locus_tag="VIA51_001243"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEQ8683186.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     LVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(8964..9656)
                     /gene="coaB"
                     /locus_tag="VIA51_001244"
     CDS             complement(8964..9656)
                     /gene="coaB"
                     /locus_tag="VIA51_001244"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEQ8683187.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKRLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9837..10688
                     /locus_tag="VIA51_001245"
     CDS             9837..10688
                     /locus_tag="VIA51_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEQ8683188.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10685..11884
                     /locus_tag="VIA51_001246"
     CDS             10685..11884
                     /locus_tag="VIA51_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEQ8683189.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11881..12879
                     /locus_tag="VIA51_001247"
     CDS             11881..12879
                     /locus_tag="VIA51_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEQ8683190.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEKAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12921..13253
                     /locus_tag="VIA51_001248"
     CDS             12921..13253
                     /locus_tag="VIA51_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEQ8683191.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13246..14058
                     /locus_tag="VIA51_001249"
     CDS             13246..14058
                     /locus_tag="VIA51_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEQ8683192.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFSPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTTIFNTFTSEDKALYDTYLQKENNCE"
     gene            14051..14932
                     /locus_tag="VIA51_001250"
     CDS             14051..14932
                     /locus_tag="VIA51_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEQ8683193.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGSRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILGTKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            14979..15998
                     /locus_tag="VIA51_001251"
     CDS             14979..15998
                     /locus_tag="VIA51_001251"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8683194.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            16126..17796
                     /locus_tag="VIA51_001252"
     CDS             16126..17796
                     /locus_tag="VIA51_001252"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8683195.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            17881..19458
                     /gene="cls"
                     /locus_tag="VIA51_001253"
     CDS             17881..19458
                     /gene="cls"
                     /locus_tag="VIA51_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEQ8683196.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMSSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            19798..20136
                     /locus_tag="VIA51_001254"
     CDS             19798..20136
                     /locus_tag="VIA51_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683197.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
BASE COUNT         6236 a         3457 c         4232 g         6453 t
ORIGIN      
        1 aactgattac caagagatta ttatcattat cttctaaggt gtcattgtta tggtgacaat
       61 caaccatacg ctactaaaga taggtagcgt tcgatcacag gttgatcaag tgattgaaaa
      121 gtcaatattt ataattttac aaatatctgt atcaatccat gttgaatagt ctatgcttct
      181 aaggtgtcga cgttaatgta ctgacgggac cgttatagtc tttctttttg gagaaacgtc
      241 ggatgccagt gaactagttg aagttaaaga tgttaattca aacagtgctg aagagattga
      301 tatcgttttg aacggtcgtt tacttcaaag caaagaaatt accagtctat cggagatgat
      361 ataagtgcta aagttagatc acgttaatta tctatcaagt cgggtgcata tttcgttaaa
      421 gtatctacag gggtttcaat agatgtagct attatgaaag gtgatgttaa atggggacta
      481 ctgatttagt tagttgtgct gtacaagcta gtgagtatgc ttatgtccct tactctcatt
      541 ttccagtagg agcagcttta aaaacaaaag atggaacgat ctatactggc tgtaatattg
      601 aaaatgttag ttttggtctg acaaattgtg gagagcgaac agctatattt aaagccatat
      661 ctgatggtca taaagaattg gttgaaattg ctatttatgg agaaactatg caacctgtat
      721 ctccttgtgg ggcttgtcgt caggtaatgg cagaattttt tgatccttct tctttagtca
      781 ctttaattgc taaaaatggt caaactgttg aaatgactgt tggagattta ctcccctatt
      841 cttttacaga tttaatataa tctgctttaa tttctgttat ctagccgtct tggctttata
      901 tttactttca gcaacttatt tgctagaaat cttttttagg agggttcata ttcatgaaca
      961 agaaatttat tggtcttggt ttagcgtcag tggctgtgct gagtttagct gcttgtggta
     1021 atcgtggtgc ttctaaaggt ggggcatcag gaaaaactga tttaaaagtt gcaatggtta
     1081 ccgatactgg tggtgtagat gacaaatcat tcaaccaatc agcatgggaa ggcctgcaat
     1141 cttggggtaa agaaatgggc cttcaaaaag gaacaggttt cgattatttt caatctacaa
     1201 gtgaatctga gtatgcaact aatctcgata cagcagtttc aggagggtat caactgattt
     1261 atggtatcgg ctttgcattg aaagatgcta ttgctaaagc agctggagat aatgaaggag
     1321 ttaagtttgt tattatcgat gatattatcg aaggaaaaga taatgtagcc agtgttacct
     1381 ttgccgacca tgaagctgct tatcttgcag gaattgcagc tgcaaaaaca acaaaaacaa
     1441 aaacagttgg tttcgtgggc ggtatggaag gaactgtcat aactcgattt gaaaaaggtt
     1501 ttgaagcagg agttaagtct gttgacgata caatccaagt taaagttgat tatgctggat
     1561 catttggtga cgctgcaaaa ggaaaaacaa tcgcagcagc tcagtatgca gcaggtgctg
     1621 atgttattta ccaggcagca ggaggcactg gagcaggtgt atttaatgaa gcaaaagcta
     1681 ttaatgaaaa acgtagtgaa gctgataaag tttgggttat tggtgttgac cgtgatcaaa
     1741 aagacgaagg aaaatacact tctaaagatg gcaaagaagc aaactttgta cttgcatcat
     1801 caatcaaaga agtcggtaaa gctgttcagt taatcaacaa gcaagtagca gataaaaaat
     1861 tccctggagg aaaaacaact gtctatggtc taaaagatgg cggtgttgaa atcgcaacta
     1921 caaatgtttc aaaagaagct gttaaagcta ttaaagaagc gaaagcaaaa attaaatctg
     1981 gtgacattaa agttcctgaa aaatagtgtt taagaacaag aagcgcgacc tttgtcggtc
     2041 gctcttttta aactgagata atttttatct cagtaaagtt tgtgataggt gatagatcat
     2101 aggctttact gaaataaaag attgcattga aaggaaatga tcctatgaca cagcatgtca
     2161 ttgaaatgag agaaatcacg aaaaaatttg gtgattttgt tgcaaatgac cacattaact
     2221 taaatgtcag aaaaggtgag attcatgcct tattgggtga aaatggggca ggtaaatcaa
     2281 ctttgatgaa tatgctagct ggtctcttag agcctactag tggagaaatt gtcattaatg
     2341 acaagccagt tcaaattgat tcgccatcta aatcagctaa gcttggtatc ggaatggtac
     2401 atcaacattt catgttagta gaagccttca cggttgctga gaatattatt ttaggaaatg
     2461 aagtagtaaa aaatgggtgc ttagatctta accaagcatc gaaagatatt aaggtactat
     2521 ccgaaaaata tggccttgca atcaatccat cagctaaagt ttctgatatt tcagtaggag
     2581 cacaacaacg tgttgagatt ttgaaaacct tgtatcgtgg tgcagatatt cttatctttg
     2641 atgagccaac tgccgtttta acacctgcag aaattaaaga attgatgact atcatgaaga
     2701 atctcgtgaa agaaggaaaa tcaattattt taattaccca taaactggac gagattcgtg
     2761 ctgtcgccga ccgtgtcaca gttattcgtc gtggtaagag tatcgaaaca gttgatgtgg
     2821 caggagcaac ttcacaagat ttagctgaga tgatggtggg acgctcggtt tcctttacaa
     2881 ctagcaaaaa agctgctgaa ccaaaagatg tggtcttatc catcaaaaat cttgaagtag
     2941 atgaaaatag aggggttcca gcagttaagg ggctatctct agatgtccga gctggtgaaa
     3001 ttgtagggat tgctggaatt gacggaaatg gtcaatctga gttaattcaa gctattacag
     3061 gtttacgtaa agtcaaatct ggaagtatta tgattaaaaa caatgaagtc actcatttgt
     3121 cttcacgcaa aattactgag ttatcagtgg gtcacgtgcc agaagatcgt catcgagatg
     3181 gtttgatact agatctttct ttagctgaaa atacagcctt acaaacctat tacaaacaac
     3241 ctctaagtca aaatggaatc ttaaattata ctaaaattaa tgactatgct cgtcaattaa
     3301 tgaaagaatt tgatgttcgc ggagccaatg agctagtacc agctagagga ttttctggtg
     3361 gtaaccaaca aaaggccatt attgctcgtg aagtggaccg tgatccagat ttacttattg
     3421 ttagccaacc aacacgtggt cttgatgtag gagctattga atatatccat aagcgtttga
     3481 ttaaagaacg tgataaaggt aaagctgtcc tcgttgttag ttttgaactt gatgaaatat
     3541 tgaatttatc tgatcgaatt gctgttattc atgatggtaa aattcaaggt atcgtatcgc
     3601 cagaaaatac caataaacaa gaattgggta ttttaatggc aggtggttca attcataagg
     3661 aggaaggtca tgtctaaaaa tgcgcaaaaa attgctgtac cattgatttc tgtcttgcta
     3721 ggatttttac ttggcgctat tattatggtt atctttggtt atgatcctat ctgggggtat
     3781 gaaggtttat tccaaattgc ctttggtagt gttaaaaata ttggagaaat attccgttca
     3841 atggggccat tgattttaat agcgcttggc tttactgttg ctagccgtgc aggcttcttt
     3901 aacgttggtt tgtctggaca ggctttagct ggatggattt cagcaggttg gtttgcactc
     3961 ttaaatccag atatgcctcg tccattattg attcttatga cagctcttat cggaatgatt
     4021 gctggtggta ttgctggagc tattccaggg atacttcgtg cttatcttgg tacaagtgaa
     4081 gttatcgtta cgattatgat gaactacatc attttatatg tcggaaatgc tattgttcaa
     4141 cgtggttatc ctgagagtgt caaacaaagt attgattcaa ctattcaagt tagtgataat
     4201 gctagttatc aaacgcattg gttatcagcc ctaactaata actctcgtat taatattggt
     4261 attttctttg ccattattgc cattgcccta atctggttct tgcttaacaa aactacttta
     4321 ggttttgaga ttcgttcagt tggtctcaac ccacatgctt cagaatacgc agggatgtca
     4381 tcaaaacgta ctatcatttt atcaatgatt atctctggag ctcttgcagg tcttggagga
     4441 gtagttgaag gtctaggaac ctttgaaaat gtttttgtac aaggatcttc tttagcagtt
     4501 ggttttgacg gtatggcagt tagcttatta gcagcaaatt caccgcttgg aatatttttc
     4561 tcatcattcc tatttggtgt cttaaatatt ggtgctccag gaatgaatat tgcaggcatt
     4621 ccaccagaac ttgttaaagt agtaactgca tcaatcattt tctttgttgg ttcacattac
     4681 ctcattgaac gttacattat tcgccctaaa aaattagtga aaggtggtaa ataagatgag
     4741 tttagtaaca atttttgcct tattgatgtc atctatgctt atttatgcaa caccactcat
     4801 tttcacaagt attggaggaa ctttctcaga gcgctcaggc gttgttaatg ttggtttaga
     4861 aggtatcatg gtcatgggag cgttctctgg gattgttttc aacttagagt ttgctgaaac
     4921 atttggaaaa gcaacgcctt ggatagccgt tttagtcggt ggtattgttg gtttgatttt
     4981 ttctttgatt cacgctgtag caaccatcaa ctttcgagct gaccacattg tcagtggtac
     5041 agtgttgaac ttgttagcac cttcttttgc tgtcttcttg gttaaagcta tgtacggtaa
     5101 gggacaaaca gacaacattc aacaatcttt tgggaagttt gatttcccag gtttatcaca
     5161 aattcctgtg attggtgata ttttctttaa aaatactagc cttattggtt acttcgccat
     5221 tgctttttcg ttctttgctt ggtttttgct ttataaaacc aggtttggtc tgcgtttacg
     5281 atcagttggg gaacaccctc aggcagctga cacacttggt attaacgtct atttgatgaa
     5341 atactatggt gtgatgatct caggttttct tggtggaata ggtggagctg tttatgctca
     5401 gtcaatctcc gttaactttg ctgtaacaac tatcttaggt cctggattta ttgctttggc
     5461 agctatgatc tttggtaaat ggaatccagt tggcgccatg ctatctagtc ttttctttgg
     5521 cttatcgcaa agtttagccg ttattggtgc tcaattacca ttactagaaa agattccaac
     5581 ggtttactta cagattgcac cttatatggt aacgattatt attttagctg ctttctttgg
     5641 tcaagcagtt gcaccaaaag ctgatggaat caactatatt aaatctaaat aacgttatat
     5701 tagtaagcct cttagtgagg tttaacagca ctcctaaagc aagatagtta ggtctagctt
     5761 taagggtgct tttttgggac ttaccgcaag tttggattgc cagtcaccat cacaatagaa
     5821 gcaagaatag actaaaaaga actaagtcag cggcttagtt ctttttgctt gtcttttgtt
     5881 tttactgata gctcttaagt tgttttagcc aacaaaggta ttgatttctg tttcaatgtt
     5941 agcaattttt tcttgagcga tgtcaagagt atcacctatt gtggcaatat agaacttgat
     6001 ttttggttca gttcctgaag ggcgaactgc aatccatgaa tcatcagcta acgtgtactt
     6061 caaaacatta cttggaggag ttgttaagtt agatattgtt ccatcatttt tagtagcggt
     6121 ttgtttttgg aaatcttcta ataatacaat atcagtattg ttaaattgtt ttggaccatt
     6181 ttcacggaat ttgtccataa tcttcttaat ttcagcagct ccatccacac ctgaaagtgt
     6241 tactgaaatc gttttttcag caaaatagcc atattctttg taaatttcat caataccatc
     6301 tgcaagtgtt aaaccacgcg aacggtaata agctgcgatc tcagcaacca aaagaactgc
     6361 ttgaatagcg tctttatcac ggacaaatgg tttaataaga tatccgaagc tttcttcaaa
     6421 accaaacata taggtgtggt tatgtttttc ttcaaactct tgaattttct cagcgatgaa
     6481 tttgaatcca gttaaaacgt taaacattgt agcgccataa ctttcggcaa tttttgttac
     6541 taattctgtt gatacgattg atttagcgag agcagcattt tctggaagtg ttcctgctgt
     6601 tttatgagct tccaggatgt atttcgcaat aatcgctcca atttgatttc cagaaaggtt
     6661 tttataagaa ccatctggtt ggcgaatttc aacgcctagg cggtctgcat caggatcagt
     6721 agctactaag acatctgcct caacttctcg tccgagttct tcagcaagag caaaggcagc
     6781 ttggctttca gggttaggcg atttaacagt agaaaagtct ggatctgcct tagcttgtga
     6841 ttcgactaca acaacagatt caaaaccggc ttgagcaagg gcacggcgtg tcaacatctc
     6901 accagttccg tggagaggag tatagacaat tttcatgtct tttccaaagt tattgattaa
     6961 atcttgattg atattaacat ctttaacctc tctaaggtat tccatatcaa catcttcacc
     7021 gataacttga ataagacctg atgatttgtt ttcatctaaa tcagcaagtt caactgcaaa
     7081 tggattttca atagcgcgga taaagtctgt tagtgcatca gcatcagctg gtggtagttg
     7141 acctccgtct tgtccataga ctttataacc attgaaaggt gctggattgt ggcttgcagt
     7201 aaccataata ccagcatagg catttaaatg gcgaacagca aaagagagtt ctggtgttgg
     7261 acgaagagct tcaaatacgt aagatttaat tccatgctgt gccaagacct gtgcagactc
     7321 aaaagcaaat tctggagaga agtggcgcga atcataagcg atagctacac cacgtttttt
     7381 agcttcctct cccttagttt cgattaattt tgctaatcct tcggttgctt gacggacaac
     7441 ataaatatta atacgatttg taccagcacc aatataacca cgcataccag cagtaccaaa
     7501 ttctaagttt gtgtaaaaag catcttcttt tgttttttca tccattgata gtaattcttg
     7561 acgaagatag tcaggaagct gctcaaaatc taaccatttt tgaaaatttt ctgtgtaagt
     7621 cattgaaata ctccttcaat atttataaac gctttcatta tatcattttg aagggaaaaa
     7681 aacactaatt atttgcagct gtttacaaaa ctttttccat attttcaagt agctaatgta
     7741 agaaagttaa aataaccaag tttttaaaag agaaaaactc ggttattgtg aaagctaatt
     7801 acctttttag tcttgatagt gttggaataa gtacaaaggt aataatagct gagatgatca
     7861 tctcaacaat agcgtttgat gagatgatgg ctgttagtag tgctttaata tttccatcaa
     7921 aaactgtcgc gaaaaaaata aatatcccag ataatacaaa tatagtattt gttagagaac
     7981 caatgatacc ggatactatt aaaccaaact gattaggaat caatttatag caataataag
     8041 gggtaatacc aatcagaata cgtgggataa tagcaattat taaagaagcg aaagttccat
     8101 gatcgacaaa aggtgaaaag agataatttg taggcagtag aatgatggta tttgtaatga
     8161 cacttataat ccccattaat cctcctaaaa tagcacctat ccttgggcca tataagacag
     8221 aagcaataat aactgggata tggacaagcg ttggtttgat tggaataggc caaatattaa
     8281 agacaagact gctcacaaaa tgaatgacta acatgatggc aaaaaagata gcaatacgag
     8341 aaatatctgc tgatttacgg tgattcattt tactctccaa aaaatataat acttaattct
     8401 aaaaaggtga tcagaaaaac gactgttaaa gtttccaaat cgtatcaata gtagctaaga
     8461 taacatcaat atcagccaaa gcaccaggtc ctttatctcc acaggctaat aagctagatt
     8521 ttggaggaat ttctgtaaac cctattgtcg ataagcgttt aatattttct tgagtaatag
     8581 ggttttgata cattttggta ttcatggctg gggctattaa ttttggtgtg gtagctggta
     8641 gggcaagagc aacacttgtt acaagattat cagcgaatcc atatgctaga tgagcaatag
     8701 tattagcaga ggcaggtgca acaataaata aatctgtgcg ttttgctaat tcgatatggt
     8761 tgataacttt tgggtcatgc tcatccataa catctaaatg aatagcattt tttgataaca
     8821 cttgcagggt taatggtgta ataaattgtg tagcagcctg agtcattatg atgtgaacat
     8881 catagccaat tttagttaat tgactcgtaa gatctgctgc tttataggca gatatactac
     8941 cagaaacagc taaggtaata tgtttagtca tgtttggtca tcctttcata taataagtca
     9001 gcaattgcct ctttggtatc tgcagatgca acttcgttat tggatatcaa aagagccttg
     9061 tgcatacctg tttggatatc aactaaatca ttggcgagaa tataatcagc gtgattttta
     9121 gctagacttg ctctggctac tttaattaac tcttcttgag gcacattaac tagaagttta
     9181 aagccgacta gtttaatatt aggattccac tgtttaacat aagagataac tttgggtgtt
     9241 tttttcaaaa aaagaacctg ataatcagat gcagatgaga ttttcggctc actgttatgt
     9301 tcacatagaa aacaattaag gttatcagct tgagagactt gttccaaatc agtcatgtag
     9361 actggagtat agtcagaaac agccatacta tgaattagaa tgtcatggtg aggaacctga
     9421 tctttgagtg cagccattaa gtcgttaact gtttccactt caataatcct taggcgctta
     9481 tttggcaggg gtttagtggc tgttttagta gtgactaggg taacgtcatg atgatattgt
     9541 aaaaatcgct ctgtgattaa ttttccaagt tgcccagttg agtgattagt gatacctcgt
     9601 actgcatcta taggttcagt tgttccacct gatgttatta ttaatttcat agtcatattt
     9661 tatcaaaaaa ggagctgata gtaaacggaa gataatgacg ccagacattg tcttgcgttt
     9721 gtattaatat ggaatagtaa tagatttcta gtaattaaaa cgaagttctg gaaagcaaga
     9781 cactatagta gctaaaatct aaattttaag gtaaaataga gcaagcggtt tcaagtgtga
     9841 aaggaagaat tgtgataact attagagatt tagcgtcact gccgattttt gtttacggtg
     9901 atggaaataa aaaagttcca ggagctttga gtccttttgt gtggacagag gtgtttttaa
     9961 aaactatcaa tcaagaacct aatcaactga tcttacatat ttggccgatg acaagaacag
    10021 ttatattagg aatgttagat agacagcttc cctactttga gctggctaaa acagagattg
    10081 gcaataatgg ttatgttcct gttactcgta atattggcgg tttggctgtt gtcgctgatg
    10141 atgggatttt gaatttttcg cttgttattc cagaccattt ttcggaatct atcagtatta
    10201 gtaatgctta tttaataatg gttgatgtca ttagagagag tttttcggat tattatcagc
    10261 gtattgaata tcacgaaatt aaaaattctt attgccctgg taattttgat cttagtattg
    10321 caggccgcaa gtttgcaggt atcgcccagc gtcgtatcaa aaagggaatt gttgtgtcta
    10381 tttacttgag cgtttgtggg gatcaagcag cgcgtggtca actcatcaag gatttttatg
    10441 aggccggaac acaaggagaa gttaccaagg ttaattaccc tcaaattgat ccagaatgca
    10501 tggcaactct ttcagaactc cttgagacgc cttttacagt ggcagaagtc cttgaacgtc
    10561 ttcgattgac cttgcgacag cttggctttt ccctcacgga aaaaagtcca gatcaagcct
    10621 tactgactaa ttttgatgct gtctatgaac ggatgcagct agaagtcgtc agaaaggaag
    10681 gcaaatgaaa gaaagattta gtcctttatt tgagcctttg actttgccaa atgggagtca
    10741 attggataat cgctttgttt tgtctcctat ggtgaccaac tcatctacaa aagacggtta
    10801 tgtcacccaa gatgatgtat cctatgcttt gagacgagca gcttctgccc ctctacaaat
    10861 tacaggagcg gcctatgtgg atccttatgg tcaattgttt gaatatggtt ttagtgttac
    10921 aaaagatgcc gatatttctg gcttgaaaga gctagctcaa gcgatgaagg caaagggagc
    10981 taaagctgtc ttacaactga cccacgctgg ccggtttgct agccatgcct tgactaaata
    11041 tggctttgtc tatgggccta gttacatgca gttgagatct ccccaacctc atgaagtcaa
    11101 acctttaaca ggtcagcaaa tagaggaatt gattgcagct tacgctcagg ccactcggcg
    11161 ggcaattcaa gcaggctttg atggcgtgga agtatcttcg gcgcagcgct tattgattca
    11221 aacgttcttt tcgacttttt cgaacaagag gacagatagt tatggttgtc aaacactttt
    11281 taatcgctct aagttaactc tagctgtttt gcaagctgtt caacaggtga ttaaacaaga
    11341 agctcctgat gggtttattt ttggatttcg tgctacacca gaagaaacta ggggaaatga
    11401 tattggttat agtattgacg agtttttgca gttgatggat tgggtactta atgttgcaaa
    11461 acttgattat ttagcgatag caagttgggg ccgtcatgta tttcgaaata ctgttcgttc
    11521 tcctggccct tattatggaa ggcgagttaa tcaggtagtt agagattatt taagaaataa
    11581 gctacctgtt atggctacag ggggaatgaa cacacctgac aaagctattg aagcactagc
    11641 tcatgctgat tttattggag tatctacacc ttttgtcgtg gatccagaat ttgctcataa
    11701 aatcaaagaa gggtgtgaag agagtattca tttaaggatt cgacctgctg atttgaaaag
    11761 tttagcgatt cctcaggctt ctttcaaaga tattgtacct ttgatggact acggggaatc
    11821 attgcctaaa gaatcaagaa ctttatttcg tagtcttact cacaattata aggagattaa
    11881 atgaaagtca gtattcttga ttatggggtg attgataaag aaaaaacacc ccaagaagct
    11941 ttattagaaa cgcgctgctt agcacaagta gccgacaaac ttggttttca tcgtttttgg
    12001 gtagcagagc atcataatat ttatgccttt gcaataagca gtccagagct gttgatgatg
    12061 catttagcag atcataccaa acagattcgg ataggttcag gaggtattat gcctctacat
    12121 tatagtagct ttaagattgc agaatggata atgactttag aggccttgca ccctaatcgg
    12181 attgatttag gtattggcaa ctctttagga actacgttag ttcaaagagc tctatcaagt
    12241 atccattgca aagacagcta tagtcaggtt gtcacagaat tataccagta tcttaatcct
    12301 gatcatttgt caccactacc gatttttgtt aaccctaggg gtaatactta ccctcagatt
    12361 tggacgctaa gcaatagttt ggagacagca gaactggctg gtcaattagg tttaggctat
    12421 acctttggta ttttccccta tataccaaaa gatcctataa cagaagctaa aagagtatcg
    12481 gcacattata gaaaggcttt taggccttca aagctattaa aaatccccaa gttaatatta
    12541 gcagttttta ttgtcctttc tgataccgac gagaaagcag aagctttggc taaaccgttg
    12601 gacatttgga tgcttggtca gcaagatttt aatgaattta agacctaccc tgatgttgag
    12661 gaggctagaa actatcactt aacagagaaa caaagagaag ccattgcagc aaatcgtagt
    12721 cgcatggtta ttggatcacc tcacacagtc aagaaacaat tggataggct gatagaagct
    12781 tgtcaagctg acgaattatt agccatcccc ttagttcctg aatttgccaa tagacaacga
    12841 accttagagc tgctagcaga cttatacgtg accatttaac cttaccaaaa acaattccct
    12901 aaactgaaag gaaagaaaca atgaaaaaaa ttgcaaatta cttattaatt gagaaaacag
    12961 atgaccgcta taccattagc atgacaccag aattacaaga cgatattggt actattggtt
    13021 acgctgaatt tacggataac gaccaccttg ccgttgatga cattatctta aatctagagg
    13081 cttctaagac tgtcatgtct gtcttgtcac cattggctgg ggcagttgtt gagcgcaatg
    13141 aggcagccac actaacacca acccttttga attcagaaaa agctgaggaa aattggattg
    13201 ttgtgctaac agatgttgat caagcagctt ttgatgccct agaagatgcc tagttcattt
    13261 gatttattag gggaaatgat tggtctgttg caaacagagc agcttactag ttcttgggcc
    13321 tgtcccttgc ctaatgcttt aacaaagcga caagacttgt ggcgggcgct cattaaccag
    13381 cgccctgctt tgcccttatc aaaagattac ttgaatctgg aagatgctta tctagatgat
    13441 tggcgtgctt cttttgttcc tgtatcagtc aaggattgcc aaaaaactaa ttataccagt
    13501 ctttttcttt accatgggga tattaggtat cttgctgtgg atgctattgt caacgctgct
    13561 aatagtgagt tattgggatg ttttagtcct aaccatggct gtattgataa tgcgattcat
    13621 acgtttgccg gaagtcgttt acgcttagct tgtcaggcaa tcatgactga acaaggccgt
    13681 aaggaagcca ttggacaagc aaagcttacc agtgcttatc atctaccagc ctcttatatt
    13741 attcataccg tagggccaag aattaccaaa ggacaccacg tttctccgat tcgagctgat
    13801 ttgttagcac gttgttatcg ttctagtctt gatttggcgg ttaaagcagg attgactagc
    13861 ctagcttttt gctctatttc aacaggagaa tttggctttc ctaaaaaaga agccgctcag
    13921 attgctatta agacagtttt aaaatggcaa gcagaacatc cagaatctaa gaccttaact
    13981 accattttta atacctttac atcagaagac aaggccttat acgacactta tttgcaaaag
    14041 gagaataact gtgagtaatt ggacaaccta tcctcagaaa aacctcaccc aggcagaaca
    14101 actggcccaa ttaatcaaag aagcagatgc acttgtagtt ggtattggag ctggcatgtc
    14161 tgcagctgat ggttttactt atatcgggtc gcgttttgag acggcattcc cagattttat
    14221 tgctaagtat cagtttttgg atatgctgca agctagcctt tttgattttg aagattggca
    14281 agaatattgg gcttttcaaa gtcgctttgt cgctttgaat tatcttgatc agcccgtagg
    14341 ccagtcttat cttgatttaa aagagatttt gggaaccaaa gactatcata ttattactac
    14401 taatgctgat aatgcttttt gggtggctgg ttatgatcct cataacattt ttcacattca
    14461 aggagaatat ggtttgtggc aatgtagcca gcactgccat cagcaaactt ataaggacga
    14521 tacggtcatc cgtcaaatga tcgcagagca aaaaaacatg aaagtcccag gtcaactgat
    14581 tcctcattgc cctgaatgtg aggcgccttt tgaaatcaat aagcgtaatg aagaaaaagg
    14641 aatggttgaa gatgctgact ttcatgccca aaaagcacgt tatgaggctt ttttatcaga
    14701 acataaagag ggtaaagtgc tttatctaga aattggtgtg ggacatacga cgcctcagtt
    14761 tatcaaacac cccttttgga aacgtgtctc agaaaatcct aatgccttat tcgttacctt
    14821 gaatcacaaa cattaccgca tccctctgtc aataaggcga caaagcctag aactgacaga
    14881 acacattgca caattgatta gcgccacaaa aaccatttac caaaaatcgt aaccaaagcc
    14941 aatagacggt taattaagag atagagaagg agactaacat gtaccttatt gaaccgattc
    15001 gtaacggtaa acgtatcacc gatggagctg ttgctctagc catgcaagtt tatgttcaag
    15061 aaaatctatt tttagatgat gatattttat ttccctacta ttgtgatccc aaagttgaaa
    15121 ttggaaaatt ccagaatgca gttgtagaaa ctaatcaaga gtatttaaaa gagcatcata
    15181 tccctgttgt tcgcagagat actggcggtg gtgccgttta tgtagattct ggtgctgtta
    15241 atatttgcta cttgattaat gataatggta tttttggtga ttttaaaaga acctatcagc
    15301 ccgctattga agcccttcat catttgggag caacagaggt tgaaatgtct ggacggaatg
    15361 acttggttat tgatgggaaa aaggtatctg gcgctgcgat gactattgct aatggccgtg
    15421 tttatggggg atattccctt ttgctagatg tggactttga agccatggaa aaagcattaa
    15481 aacctaatcg caaaaaaatt gaatcaaaag gcatcaggtc agttcgtagt cgcgttggaa
    15541 acatcagaga acatttagca ccacaatacc aaggtattac gattgaagag ttcaaagatt
    15601 taatggtttg ccaattgtta cagattgaga cgattagcca agctaagcgt tatgatttaa
    15661 cggaaaaaga ctggcaacaa attgatgctt taacagagcg caaatatcac aattgggaat
    15721 ggaattatgg caacgcgcct caataccgtt accatagaga tggccgtttt accggtggaa
    15781 cagtagatat tcatttagat attaaaaaag gctatattgc agcttgtcgc atttacggag
    15841 atttttttgg caaggcagac attgcagaac ttgaaggtca cttgatagga acacgaatgg
    15901 aaaaagagga tgtcttagct accctcaatg caattgattt agccccttat ttaggtgcga
    15961 ttacagcaga agaattagga gatttgatat tttcttgata aaaaagatac ctcagaccgg
    16021 taaagtgtga ttaaaaacga acaataattg ttttaattca aataaatgta cgtatgatat
    16081 gaattgtgat ataatgacgt cattacgtaa aattgaggag tcatcatgaa atcagatatc
    16141 gaaattgccc aaagtgtcgc cttacaacca atcactgaca ttgttaaaaa ggttggaata
    16201 gacggcgatg acattgagct ttatggcaaa tataaggcta aattgtcttt tgagaaaatg
    16261 aaagctgtcg aagctaatga gcctggaaaa ttaatcttgg taactgctat taaccctact
    16321 ccagcaggag aaggaaaatc aaccatgtct attggactgg cagatgcctt aaatcaaatg
    16381 ggaaaaaaaa ccatgcttgc cttacgtgaa ccctcccttg gtcctgttat ggggattaaa
    16441 ggcggggcag caggtggtgg ttatgcccaa gtattgccta tggaagacat taatcttcac
    16501 tttactggtg acatgcatgc cattacaacc gctaataatg cattatctgc tttgattgac
    16561 aatcatttgc agcaaggaaa cgatttagga attgatcctc gccgcattat ttggaagcgc
    16621 gtgttggacc ttaatgatcg tgctcttcgt caggtaattg ttggcttagg tagtccagtg
    16681 aatggtgtgc cacgcgaaga tgggttcgat atcacagtag cttctgaaat catggcaatt
    16741 ttatgtttgg caactgactt aaaagatcta aagaaacgtc ttgctgatat cgttgtggct
    16801 tatacctatg atcgtaagcc tgtctatgtg cgtgacttga aggttgaagg agccttgaca
    16861 ttaattctaa aagatgctat caagccaaac ttggtgcaga ctatttatgg aacaccagct
    16921 cttattcatg gggggccatt tgctaatatt gctcatggtt gtaattctgt ccttgctacc
    16981 tcaacagctt tgcgattagc agattacact gttaccgaag caggattcgg ggccgaccta
    17041 ggagctgaaa aattcctaaa tatcaaagta cctaatcttc ctaaagcacc agatgctatc
    17101 gttattgttg caaccttgcg cgcccttaaa atgcatggag gtgtcgccaa atcagattta
    17161 gccgctgaaa attgtgaggc tgttcgctta ggatttgcca acttaaaacg tcacgtggaa
    17221 aacatgcgcc aattcaaagt tccagttgtg gtggctatca atgaatttgt agcagatacc
    17281 gaggctgaaa ttgctacctt aaaagcgctt tgtgaagaga ttaaggttcc agtagaatta
    17341 gccagtgttt gggcaaatgg agctgaggga ggcttagcat tagctaaaac agtggttcgt
    17401 gtgattgatc aagaagctgc tgactacaaa cgtctctatt cagatgagga tactttggaa
    17461 gaaaaagtga tcaatatcgt tacccagatt tatggtggca aagctgttca atttggcccc
    17521 aaggccaaaa cacaattgaa gcagttcgca gaattcggtt gggataaatt gcctgtttgt
    17581 atggctaaga cccaatacag tttttcagat aacccatcct tgcttggagc gccaaccgat
    17641 tttgacatta ccattcgtga atttgttcct aaaacaggag caggttttat tgttggttta
    17701 acaggtgatg tgatgaccat gcctggtttg cctaaagttc cagctgccat ggcaatggat
    17761 gtagcagaaa atggcacagc cctcggtctc ttttaggaaa aattgctcga ataattcgag
    17821 caagcgctcc tttcttcccg ctttactgtg atataataag gtaaatgaga ttttggaggg
    17881 atgattatca aaaagaaagc aaaagtaaaa tatttgctcc ataaagggaa acatggattt
    17941 ttaagaggaa tttttagtag aacaacaatc attgtattat taattatttt gcaattagtt
    18001 ttcttatttc aatcttatgc ctggatggag cagtaccgtg tttggataac gattcttgaa
    18061 agtgtctttg ctattactat tgttttatat ttagttaata gtgatatgga tgctatttca
    18121 agaatgacgt ggttaatttt gattatgatt gctccattac tagggtcact gtttttaatt
    18181 tatacaaaat tggattgggg ttacagaggg ctaaaacaaa gaataaatca tcttgtagat
    18241 ctgtctgcac cttaccttag cgatgatgac gctatattag aggtattaaa ggatagcaca
    18301 tcaaccacat atcatttagt acagtactta gaaagaagtc gtggcaactt tccgatttat
    18361 aataatacaa gggtaactta cttcccaaca ggtgaaactt tttttgatag tttaaaagaa
    18421 cagttattct tagctaaaaa gtacattttt cttgaatttt ttattattgc agaaggccaa
    18481 atgtggggag aaatccttag tattctagaa aaaaaagtca gtgaaggtgt agaagttagg
    18541 gtgttgtttg atggcatgaa cgaactatca acgctatcat cagattacgc caagagatta
    18601 gaacaaatag ggattaaagc taaatcattt ttaccgattt caccctttat ctctacctat
    18661 tacaattatc gagatcaccg aaaaattgtc gttattgatg gggaggtatc attcactgga
    18721 ggtattaatc tagcagatga gtacattaat gaagtagagc gttttggcca ctggaaagat
    18781 gctggtttaa tgcttgaggg tgaagcaaca gacagctttt taattttgtt tttacaaatg
    18841 tggtctatca cagaaaaaga actgattatt gatccttatc tttcagatca ttctttaaaa
    18901 cttccttcag atggctatgt tattccctac ggtgattccc cgcttgatac tgataaaata
    18961 ggtaaaaatg tttatataga cattttaaat catgctaaag agtacgttta tatcatgaca
    19021 ccttacctta ttttagatag cgagatggaa cacgctttac ggtttgcatc agaacgtgga
    19081 gtagatatcc gaattattat gccaggagtg ccagataagg gggtaccata tgccttagct
    19141 aaaacctatt ataaagcttt gatgtcttct ggagtaaaaa tttatgagta tcaaccaggg
    19201 ttcgttcatt caaaggtatt tatctctgat aatacaaaag cagttgtcgg aacaattaac
    19261 ttagactatc gtagccttta tcatcatttt gaatgcgcga cttatttata tcgtgtgtca
    19321 gttattgctg atattgtgaa tgactttaat gaagctcaaa agcaatcact attgatgaca
    19381 tcagatcatt tgacgcaacg tccttggtat caaaaattga taggattatt agtacgaaca
    19441 attgcccctc tcttgtaatt ttcgtaaaat atgttataat atctgtatgc gatgagtcga
    19501 ttgtgactgc aaagtcactt ttgcgcaggg gaggtcatta aggcgggaag ccgactttga
    19561 taatctgtgt gaaccatttt atcacaatct tatttattaa gaatgcccct tggattgaga
    19621 tattctcaat ccttttttta attttattat cttagttaaa attcagaatg tatcagtgat
    19681 tactgtgttt caaaataaga aagtagtttt tcgggtatga gtgctatgac ttgacaaatg
    19741 ctaataacat ttgcataatg taggtagaga tgaaaactta tgaaaagaga tgatcttatg
    19801 caaattatta agcgtgatgg ccacgttgct gattttgatc cagataaaat ttatcaagca
    19861 attattaaag cagcaaggac ggtctatgtt attgatgaca cgtggcgaca aaacttaaca
    19921 catgtcacta aaaaagtagt tattgattta gaagaagcac atgtagaacg tcctactatc
    19981 aatatggtcc aatcccttgt ggagaatcgt ttgatggatg ctggatatat taccattgca
    20041 gaacattaca tttcttatcg tcttcagcga gatttagagc gcaatggcta tggtgataag
    20101 attgtggttc acttgcgttt tgaacaaata aaataaaaac gcttctaatg gcattttagt
    20161 gtctttgagg ggataaggtt taaataccta acagataaaa atctgttagg tatttttttg
    20221 ctactattag gtgtattcta tattacatag aacttaagca ttcaagcttt agtttaactt
    20281 tctgtttatt ttttgctaca ttttgggaaa ctcccctcct ttcttagttg aggtgaataa
    20341 acttttattt gataaattat atccttagtc ttaatgaa
//
LOCUS       DAUGQX010000034        19922 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUGQX010000034 DAUGQX010000000
VERSION     DAUGQX010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19922
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.034"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            12..932
                     /locus_tag="VIA51_001255"
     CDS             12..932
                     /locus_tag="VIA51_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEQ8683198.1"
                     /translation="MSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTK
                     AIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVK
                     NAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDP
                     KNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAY
                     IWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFT
                     DSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            996..1721
                     /locus_tag="VIA51_001256"
     CDS             996..1721
                     /locus_tag="VIA51_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683199.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            1722..2576
                     /locus_tag="VIA51_001257"
     CDS             1722..2576
                     /locus_tag="VIA51_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8683200.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(2724..3530)
                     /locus_tag="VIA51_001258"
     CDS             complement(2724..3530)
                     /locus_tag="VIA51_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ8683201.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            3747..6152
                     /locus_tag="VIA51_001259"
     CDS             3747..6152
                     /locus_tag="VIA51_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8683202.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(6222..6575)
                     /locus_tag="VIA51_001260"
     CDS             complement(6222..6575)
                     /locus_tag="VIA51_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEQ8683203.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            6819..7244
                     /gene="rplK"
                     /locus_tag="VIA51_001261"
     CDS             6819..7244
                     /gene="rplK"
                     /locus_tag="VIA51_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEQ8683204.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            7350..8039
                     /gene="rplA"
                     /locus_tag="VIA51_001262"
     CDS             7350..8039
                     /gene="rplA"
                     /locus_tag="VIA51_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEQ8683205.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            8362..9090
                     /locus_tag="VIA51_001263"
     CDS             8362..9090
                     /locus_tag="VIA51_001263"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEQ8683206.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            9119..9676
                     /gene="frr"
                     /locus_tag="VIA51_001264"
     CDS             9119..9676
                     /gene="frr"
                     /locus_tag="VIA51_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEQ8683207.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            9785..10642
                     /locus_tag="VIA51_001265"
     CDS             9785..10642
                     /locus_tag="VIA51_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8683208.1"
                     /translation="MNDLLATVITGLIKEENANDYFIHKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIEQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHSSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKASFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            10715..11224
                     /gene="msrA"
                     /locus_tag="VIA51_001266"
     CDS             10715..11224
                     /gene="msrA"
                     /locus_tag="VIA51_001266"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEQ8683209.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWTQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            11221..11436
                     /locus_tag="VIA51_001267"
     CDS             11221..11436
                     /locus_tag="VIA51_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEQ8683210.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            11592..12761
                     /locus_tag="VIA51_001268"
     CDS             11592..12761
                     /locus_tag="VIA51_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8683211.1"
                     /translation="MIITKKSLFVTSVALSLVPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATNL
                     TVQAPASSPASVSHVPSSEPLPQASATSQPTVPMAPPATPSDVPTTPFASAKPDSSVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEAPTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMN
                     AGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYA
                     IDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            13075..14847
                     /locus_tag="VIA51_001269"
     CDS             13075..14847
                     /locus_tag="VIA51_001269"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEQ8683212.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKENETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            15006..16058
                     /locus_tag="VIA51_001270"
     CDS             15006..16058
                     /locus_tag="VIA51_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEQ8683213.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            16104..16679
                     /locus_tag="VIA51_001271"
     CDS             16104..16679
                     /locus_tag="VIA51_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEQ8683214.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQGTKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            16838..17335
                     /gene="ybeY"
                     /locus_tag="VIA51_001272"
     CDS             16838..17335
                     /gene="ybeY"
                     /locus_tag="VIA51_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEQ8683215.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            17316..17723
                     /locus_tag="VIA51_001273"
     CDS             17316..17723
                     /locus_tag="VIA51_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEQ8683216.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            17843..18739
                     /gene="era"
                     /locus_tag="VIA51_001274"
     CDS             17843..18739
                     /gene="era"
                     /locus_tag="VIA51_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEQ8683217.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFHSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            18759..19235
                     /locus_tag="VIA51_001275"
     CDS             18759..19235
                     /locus_tag="VIA51_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8683218.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WTIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
BASE COUNT         6177 a         3508 c         4285 g         5952 t
ORIGIN      
        1 tgggaaagag aatgagcctc attttgggtg cttttttatc tgtttttctt ttagtagctt
       61 gttcgtcaac tggcactaaa actgctaaga gtgataaatt aaaagtcgtg gcaaccaatt
      121 caattattgc cgacatgaca aaagctattg ctggtgataa aatcgatctg cacagcattg
      181 tgccaatcgg tcaagaccct catgagtacg aaccattacc agaagatgtt gaaaaaacaa
      241 gtaatgctga tgtgattttc tataatggta tcaatctaga agatggcggg caagcttggt
      301 tcaccaaact agtgaaaaat gctcaaaaaa cgaaaaacaa agattacttt gccgtgtctg
      361 atggcattga tgtgatttac ttggaaggtg caagcgaaaa aggaaaagaa gatccacatg
      421 cttggttaaa tctcgaaaac ggaatcattt attcaaaaaa cattgccaaa caattgattg
      481 caaaggatcc taaaaacaaa gaaacttatg aaaagaacct aaaagcttat gtggctaaat
      541 tggaaaaact agacaaagaa gccaaatcaa aatttgatgc tattgcagaa aataaaaaat
      601 tgattgtgac tagtgaaggc tgcttcaagt acttttcaaa agcttacggt gtcccatctg
      661 cttatatctg ggaaattaac accgaagaag aaggaacacc agatcaaatt tcatcattga
      721 ttgaaaaact aaaagtcatc aagccatctg cgctttttgt agagtcaagt gtcgatagac
      781 gccctatgga aactgtttct aaagatagtg gtattcctat ttattctgag atctttacag
      841 attcaattgc taaaaaaggt aaacctggcg atagttatta tgctatgatg aaatggaacc
      901 ttgacaaaat ttctgaaggt ctagcaaaat aagataacaa taaagcacag cgattttagt
      961 gttgtgcttt gttttattta tgtaaaggag acaaaatgat tacaactaac aatctttgtg
     1021 tgacctacga tggcaacagt aatgctttag aagcgattaa tgtgacaatt gaaggtcctt
     1081 ctatcgttgg tattattggt cctaatggag ctggaaaatc aacctttatg aaagctatct
     1141 taaatcttat tgattatcaa ggtcacgtaa cggttgatgg caaagatggt cgtaagcttg
     1201 ggcatacagt agcttacgta gaacaacgaa gcatgattga ctataatttt cctattactg
     1261 ttaaagaatg tgttgcgcta gggacttata gtaaattagg cctttttcgc cgagtaggaa
     1321 aaaaacaatt tgagcaggtt gataaggttc tcaaacaagt tggtttagaa gactttggcc
     1381 atcgaccgat aaaatcctta tctggtggtc agtttcagcg gatgttggtt gcgcgttgct
     1441 tgattcaaga atcagactat attttcttag atgaaccgtt tgttggcatt gactcggtca
     1501 gcgaaaaaat cattgtagat cttttgaaag agctcaaaat ggctggcaaa acgattttaa
     1561 ttgtacatca tgatttgagc aaagtagagc attattttga caaactcatg attttaaata
     1621 aacatttggt ggcttatggc aacgtttgtg aggtatttac tgttgatacc ttgtcaaaag
     1681 cttatggcaa tcatttgatt ttaggaaagg agatggtgta aatgtctatg aaattttttg
     1741 agggcttgat gtcataccac tttttacaaa atgcactgat aacggctgta gtcattggta
     1801 tcgtctcagg tgctgtaggg tgttttatta tccttaggtc aatgtctctt atgggtgatg
     1861 ccatctcaca cgctgtttta ccaggggttg ctttgtcatt tattttagga gtcaattttt
     1921 ttattggagc gattattttt gggttattag cttctgttat tattacttat atcaaggaaa
     1981 actctgtcat taaaggagat acggctattg gtatcacctt tagctctttt ttggcactgg
     2041 gagtcatctt gataggggta gccaatagtt cgacggactt atttcatatt ttgtttggga
     2101 atattttagc tgtgcaagat agcgataagt ggattactat tggtgtttcg atttttgttt
     2161 tagtggttat tagtctcttt ttcaaagaac tattattaac atcatttgat cctatcttag
     2221 ccaaatcaat gggtgtgaag gtcaatgcgt atcattattt gttgatggtc ctattaactt
     2281 tagtggctgt tacggcgatg caaagcgtgg gtactatctt gattgttgcc ttattgatta
     2341 cgccagcagc gacagcttat ttatatgcta atagcttaaa agtaatgtta gtgatgtcat
     2401 ctttactagg cgctttagca tcggttttag ggctttattt gggctatacc tttaatgttg
     2461 ccgcagggtc aagtatcgta ctgacttctg cgatgatgtt tttgatcagt ttctttgttt
     2521 cacccaagca aggctacctt aaaagatgga tgcaaaaaaa agaaaaaaca ccttaaactt
     2581 ttcgctttaa acaccttagt ggtttgcaaa tagtagcaaa taacatcaaa gggtgttttt
     2641 tatatgtcat caaaagacca taaaaaacct tatcaaacca aggtatttag cctattatct
     2701 gataaggttt ttttaagcat gatttagttt ttaaagcgat aatctttgac aatgtcaatt
     2761 gaggtaatcg taatgtcttg ttctggttta tcattttggt tgatagaagt agcggcaatt
     2821 ttatcgacaa catccatacc atcaatgact tgaccaaata cagtataacc gccatctaag
     2881 cttggattgc cgccatgctc ataggcagag atgataggtt ttgggtagtt ggtacttgat
     2941 aatcccttgc tttgattttt cttgttttgg ttgatataaa attggctacc gttagtatta
     3001 gcaccagcat ttgccatggc aagagcaccg cgaatatgat ataaaaatgg agagatttcg
     3061 ttgacaaagc cattgccagc atctttttta ggatccttgc ctttccaaat cgattcacca
     3121 cctgtgccat ctcctttggg gtcacctgat tgaatcataa agtcgttgat cacacgatgg
     3181 aaggtaaggt tatcatagta gcctttttta gcatgggtga ggaagttctc aacagctaag
     3241 ggagcatatt ttgggaataa cttaagggta atgtcccctt gacttgtcct cattacgacc
     3301 ttagcttctt ctttgccgac ttctttggtt agttgtggaa attggctagc atcagctttg
     3361 agagcttttt gaatgctttc ttcataggct ttagaagctg cttcgctttc ttctttggca
     3421 gttttttcat caatgtattt atcgcctttt atagcgcggt caacagattc acaagcactc
     3481 aaactaagta aactaatggc tactaaactg agagataata attttttcat gtctactcct
     3541 aagaatgatt ttctttattt tatcataaaa tgcaacagaa aatagtagta aagagttaaa
     3601 aacgcctatt tttgtgtttt atgatctaac cttggttaaa aggctgctac gactgttatt
     3661 atagcacaag atgctataga aaaacttaaa acaccttggt tttttagagc tatttcctaa
     3721 tagttaaaaa atggtataat agtgttatgg ttaaaagaaa tcaaagaaaa aaaagtgcgc
     3781 ctaagaagcg tttaacaaaa gcagaagtgg aaaagcaacg tgccattaag aggatgattt
     3841 tatctgtttt aatggctttg ttgcttattt ttgcgatgct tcgcttgggc gtctttggtg
     3901 tgacaactta taatatgatt cgttttttgg tgggtagttt agcctatccg tttatgtttg
     3961 cctggttaat ttacttattt tgttttaaat ggttacggca aaaagatgga atgattgcgg
     4021 gagttgttat tgcctttttg ggattgctag ttgagtggca cgccttctta tttgcgatgc
     4081 ctaggatgct tgatcaagat atttttctag gcactgctcg gctaattaca agagatttac
     4141 tagccctgcg cgtgactgaa tttgttggtg gaggaatgct tggtgcatta ctttataaac
     4201 ccatagcctt tttattttcg aatatcggct cttactttat tggttttttg tttatcttat
     4261 taggattatt tctaatgacg ccttgggata tctatgatgt gagtcacttt gtgaaagagg
     4321 ctgttgataa actagcagtg gcttatcagg aaaataaaga aaagcggttc atcaaacgag
     4381 aagagcaccg cttacaagct gaaaaagagg ctttagagaa acaagcacaa gaggaagaaa
     4441 aacgtctagc agaattgacg gttgatcctg agacgggaga gattgttgag gatagtcagt
     4501 ctcaagtcag ctatgatttg gctgaggata tgacaaaaga accagagatt cttgcttatg
     4561 atagtcacct caaagacgat gagacaagct tatttgatca agaagacttg gcttacgctc
     4621 atgaggaaat tggggcttat gactctttat ctgctttagc atcttctgaa gatgagatgg
     4681 atatggatga acctgttgaa gttgatttca caccaaaaac ccatcttctt tataaacttc
     4741 caacgataga tttatttgca ccagataagc ccaaaaacca gtccaaagag aaaaacttag
     4801 tccgcaaaaa tatcaaggtg cttgaagata ccttccaaag ttttgggatt gatgtcaagg
     4861 tagagcgagc agaaatcggg ccttccgtca ccaaatatga aatcaagcca gctgtcgggg
     4921 tccgagttaa tcgtatttca aatcttgctg atgatttggc acttgctctg gctgctaaag
     4981 atgttcgtat tgaagcacca attcctggaa aatccttaat aggtattgaa gttcctaact
     5041 cagaaattgc aacggtttct ttccgcgaac tttgggaaca atctgatgcc aatcctgaaa
     5101 accttttaga agtaccacta ggtaaagctg ttaatggcaa tgcgcgcagt tttaacttag
     5161 ctagaatgcc gcatcttttg gtagctggtt caactggttc aggtaaatct gtggcagtta
     5221 atggcattat ttcaagtatt ttgatgaagg cacgtccaga tcaagttaag tttatgatga
     5281 ttgaccccaa aatggttgaa ttatctgttt ataatgatat tccacattta ttaatcccag
     5341 ttgtaaccaa tccgcgtaaa gccagtaagg cactccaaaa agtggttgat gagatggaaa
     5401 accgctacga gttatttagt aaaattggtg tgcgtaatat agcaggttat aatacaaagg
     5461 ttgaagagtt taatgcttct tctgagcaaa aacaaatacc gttgccttta atcgttgtca
     5521 ttgtagatga attggctgac ttgatgatgg tggctagtaa agaagttgaa gatgctatta
     5581 ttcgtttggg acaaaaagca cgtgctgcag gtatccatat gattcttgca actcaacgtc
     5641 cctctgtaga tgttatttct ggtttgatta aagcaaatgt tccgtcgcgt atggcatttg
     5701 ctgtttcaag tggtactgat agccgtacga tccttgatga aaatggtgct gaaaagctct
     5761 tgggacgggg tgatatgctc tttaagccga ttgatgaaaa tcaccctgtt cgcttgcaag
     5821 ggtctttcat ctcagatgat gatgtggagc gtattgtcaa ctttatcaaa gaccaagctg
     5881 aagcggatta tgatgacgcc tttgatcctg gtgaagttag cgacaatgat cctggttttt
     5941 ctggaaatgg cggagctgct gaaggtgatc ctctttttga agaagcaaaa gccttggtct
     6001 tagaaacaca aaaagctagt gcctcaatga ttcaaaggcg tttgtcggtt ggatttaatc
     6061 gtgccacgcg cttgatggat gaattggaag aagcaggtgt tatcggtcca gcagaaggaa
     6121 ccaagcctcg taaggtattg cagacaaact aaaagaacct gacgtctcat gatgagatgt
     6181 taggttcttt ttttgtgatg tcaagccagt tgatgagatg cctatgctaa tgtaaaaata
     6241 aagataacta gaatcaggta gaaaataacg gtgactaaaa agccaactcg ccaaaatagc
     6301 ttcataaagc gatggtaaga aaacgactga gttcggatga ctagcagtag tgaaatgacg
     6361 atggctagca gcgacatgat aataaggtaa taaggcagta aattatgggt gaaaaatttt
     6421 cctgagacaa gcacaatttc tatcgcaaaa agtaaaagtg cgacatctgg aaatttaaat
     6481 ccctttttat taagtttaaa taaagaggtt acaatcatgg caaaaagagg cgttactatc
     6541 aagaaagcta aggcagttaa tttatagatc atcataggtc tattttatac tcaaatccct
     6601 tacttgtaaa ctgatactta cctgttgtga tagaaaatga tctttgagag ggaaagcgtc
     6661 tacttcaatt taaacattgc aaaaggcatc agctatttta acaaaaagac ttgatttatt
     6721 ttggcaataa gctataatgg taaggtatgc aatattgcat atctgtggga ggtaaaaatc
     6781 tcaattaccg ccaaaaccac aacaggagga tttttaaaat ggctaaaaaa gtcgaaaaac
     6841 ttgtaaaact tcaaatccct gctggtaaag ctacaccagc tccaccagtt ggaccagctc
     6901 ttggtcaagc aggtatcaac atcatgggct tcactaaaga atttaacgct cgtacagctg
     6961 atcaagctgg tatgatcatc ccagttgtta tctcagttta tgaagacaaa tcatttgatt
     7021 tcatcactaa aacaccacca gctgctgttc ttttgaaaaa agctgcaggt gttgaaaaag
     7081 gatcaggtac acctaacact actaaggttg cgacagttac tcgtgcacaa gtacaagaaa
     7141 ttgctgaaac taagatgcca gatttgaacg ctgcaaacat tgaagctgca atgcgtatga
     7201 tcgaaggtac tgctcgttct atgggattca ctgttactga ctagtcagtc aagaacccct
     7261 attacccgca cgacttcatc ataagagatg agtgacgtgg gagattttaa atcaaatcga
     7321 tatgaccaca ttacaaggag aattttaaaa tggctaaaaa aagcaaacaa atgcgtgctg
     7381 cacttgaaaa agtagatagc acaaaagcgt acagtgtaga agaagctgta gcattagtaa
     7441 aagaaacgaa cttcgcaaaa tttgatgcgt ctgttgaagt tgcttacaac ttgaacattg
     7501 acgttcgtaa agcagaccaa caaatccgtg gcgcaatggt attgccaaac ggaactggta
     7561 aaacacaacg tgttcttgtt tttgcacgtg gtgcaaaagc tgaagaagca aaagcagctg
     7621 gtgcagactt cgtaggtgaa gacgaccttg ttgcaaaaat caatggtgga tggcttgact
     7681 ttgacgttgt tatcgcaacg ccagacatga tggctatcgt aggtcgtctt ggacgtgtcc
     7741 ttggacctcg taacttgatg ccaaacccta aaactggtac agtaacgatg gatgttgcta
     7801 aagccgttga agagtctaaa ggtggtaaaa tcacttaccg tgctgacaaa gcaggtaatg
     7861 ttcaagctct tattggtaaa gtttcatttg atgctgacaa attggttgaa aacttcaaag
     7921 ccttccacga tgtaatggct aaagctaaac ctgcaacagc taaaggaact tacatggcaa
     7981 acgtctcaat cacatcaaca caaggtgttg gtatcaaggt tgatcctaac tcactttaag
     8041 aaaaaaatta gggcatcgcc taatcatagc aaaaagacaa atttctgaag acaaatcttc
     8101 actagaggtt tgtctttttt atggtttaaa atgggatgca aacaaaaaag tgtaggcgat
     8161 aataccatga aaggagttga ttctcttaat gagatgtggt gttaacacat catgagctca
     8221 caaaaaatga taaaggaagt atcggtggtg ttaaaaaaag ggattttaat tgacatttat
     8281 tagcctctaa aatgtccttt ccctattcat aattgagggt ttgtggtaaa atagtaagga
     8341 caaactaagg agaacatagt agtggaacct aaatatcaac gtatattaat taagttatct
     8401 ggtgaagcat tagcaggtga aaaaggagtt ggcattgaca ttccaactgt tcaggctatt
     8461 gcaaaagaaa ttgccgaagt tcatgtgtcg ggagtacaga tcgctcttgt tattggtgga
     8521 ggcaatctct ggcgtggaga gcctgcagca gacgctggaa tggaccgtgt tcaggctgat
     8581 tacactggca tgcttggaac ggtgatgaat gccctagtca tggctgatag tcttcaacat
     8641 tatggtgttg atacccgtgt gcaaacagct attcctatgc aaaatgtagc agaaccttat
     8701 attcgcggac gtgccttgcg ccatctagaa aaaaatcgga ttgttgtttt tggagctggt
     8761 attggctcgc cttatttttc aacagacacc accgcggcac tgcgtgctgc tgagattgaa
     8821 gcagatgcta ttttaatggc aaaaaatggt gtggatgggg tctataatgc tgatcctaaa
     8881 aaagatgcta atgcggttaa atttgatgaa ttaacacatg gtgaagtgat caaacgtggt
     8941 ctcaaaatca tggatgcaac ggcatcgacc ttatcgatgg ataacgatat tgatttggtg
     9001 gttttcaata tgaatgaagc tggcaatatt caacgtgttg tctttggaga acatattgga
     9061 actactgtat caaataaagt ttgtgactaa aagttagaaa agaaagagag taattatcat
     9121 ggcaaatgca attattgaaa ctgcaaaaga acgttttgca caatcccatc agtctttatc
     9181 acgtgaatat gccagcattc gtgcgggtcg tgccaacgct agtcttttag accgtatcca
     9241 agttgattat tacggggcac cgacaccatt aaatcaattg gcttcaatca ctgtaccaga
     9301 agcgcgtgtc ttattgatct cgccttttga taaatcttct atcaaagata tcgagcgcgc
     9361 tcttaacgca tcagatttag gcattacacc tgctaacgat ggctctgtca ttcgtttggt
     9421 tattccagct ttgaccgaag aaacacgtaa agaattagcc aaagaagtga aaaaagttgg
     9481 tgaaaatgct aaaattgcaa tccgtaatat ccgccgcgat gctatggatg atgctaaaaa
     9541 gcaagaaaaa gcaaaagaaa tcactgaaga tgagttaaaa acacttgaga aagatatcca
     9601 aaaagcaacc gatgatgcta tcaaagaaat tgaccgcatg acggctgaaa aagaaaaaga
     9661 attgctctca gtgtaacagg attcctacga aaaatagacg actatagaca caaaaagata
     9721 ggtgaccatt tcagaagcgt ttggttttga tttgtcccta tctttttaaa gaaagaaaaa
     9781 agatatgaat gatttactag caacagtcat tactgggctt attaaagaag aaaacgctaa
     9841 tgactatttt atccacaaag aagggtttac ctttaccttg tctaaagcag aaggagaacg
     9901 ccagattggt gatatggtca caggctttgc ctatacagac atagagcaaa aggcacgtct
     9961 cacaaccaaa gagatccgtt caacacggac aagttatggc tggggggaag tgacagaggt
    10021 tcgtcgtgac ctaggcgttt ttgtcgatac aggaattcca aataaagaaa ttgtggtttc
    10081 tttggacgtg ttgcctgaga tgaaagaact atggcctaaa aaaggggata aactttacat
    10141 tcgtttggat gtggataaaa aagaccgtat ttggggactt ccagcagagc ctgaggtctt
    10201 tcaaaagatg gctagccctg cttacaataa catgcaaaat caacattggc cagcaattgt
    10261 ttaccgccta aaattaacag gaacgtttgt ttacctgcct gaaaacaaca tgttgggctt
    10321 tattcactca agtgaacgct acgcagaacc gcgcttaggt caggttttag atgcccgtgt
    10381 gattgggttt agagaggtcg atcgtacctt gaatttatcg ttgaaaccac gttcttttga
    10441 gatgttggag aatgacgctc agatgattgt tacttatctg gaagccaatg gtggtttcat
    10501 gactttaaat gacaaatcaa gtccagaaga gattaaagca agctttggta tttcaaaagg
    10561 ccagtttaaa aaagccttgg gtggattgat gaaagctaaa cgtatcaaac aagacgccac
    10621 aggaactgaa ttaataggat aaaaatgctt tgccactggc aaagtttttt gttacaatga
    10681 agaccattaa gtgaagaaaa aggggatata gagaatggaa agagccattt ttgcaggagg
    10741 ttgtttctgg tgtatggtgc aaccttttga ggagcaagca ggtattttgt cagtcagaag
    10801 tggctacaca ggtgggcatc tcccaaatcc tagctatgaa caagtttgtg ccaaaacaac
    10861 aggacataca gaagctgttg aaattatttt tgaccctaag caaatcgctt ataaagattt
    10921 ggtagagctc tattggacgc agacggatcc aacagacgcc tttgggcaat ttgaagatcg
    10981 tggggacaac taccgtcctg tcatttacta cacaacggaa agacaaaaag aaattgcaga
    11041 gcaatcaaaa gcaaacttgc aagcttcagg acgttttgac caacccattg tcaccactat
    11101 tgaaccagca gagccatttt atctcgcaga ggattatcac caaggatttt ataaaaagaa
    11161 tcccaagcgg tatgcacaaa gcagtgctat tcgtcatcag tttttagagg agaattggtc
    11221 atgagaaaat cattttacag ctggctgatg acacaacgta accctaaatc aaatgaacct
    11281 gtggcgattt tagcagattt ggtgtttgat gacaccactt ttccaaagca taccaatgat
    11341 tttgaactca ttagtcggta tctagaagat caagctagtt tttcctttaa tttaggtcaa
    11401 tttgatgaaa tctgggaaga ttatctagca cattaatacg tggataaaaa agagtcatat
    11461 cgactctttt gaagggttat cacgttatta ttacaaaatg acatcacttt ctttcaaaaa
    11521 aatgacaagc tacttttttt cttaaaaata tgctatgata tagcttagaa aaaaataaaa
    11581 aggaagcaga gatgattatt actaaaaaga gcttatttgt gacaagtgtc gctttgtcgt
    11641 tagtaccttt ggcgacagcg caggcacaag agtggacacc acgatcggtt acagaaatca
    11701 agtctgaact cgtcctagtt gataatgttt ttacttatac tgtaaaatac ggtgacactt
    11761 taagcacaat tgctgaagca atggggattg atgtgcatgt cttaggagat attaatcata
    11821 ttgctaatat tgacctaatt tttccagaca cgatcctaac agcaaactac aatcaacacg
    11881 gtcaggcaac gaatttgacg gttcaagcac ctgcttctag tccagctagc gttagtcatg
    11941 tacctagcag tgagccatta ccccaagcat ctgccacctc tcaaccgact gttcctatgg
    12001 caccacctgc gacaccatct gatgtcccaa cgacaccatt cgcatctgca aagccagata
    12061 gttctgtgac agcgtcatct gagctcacat cgtcaacgaa tgatgtttcg actgagttgt
    12121 ctagcgaatc acaaaagcag ccagaagtac cacaagaagc agttccaact cctaaagcag
    12181 ctgaaacgac tgaagtcgaa cctaagacag acatctcaga agccccaact tcagctaata
    12241 ggcctgtacc taacgagagt gcttcagaag aagtttcttc tgcggcccca gcacaagccc
    12301 cagcagaaaa agaagaaacc tctgcgccag cagcacaaaa agctgtagct gacaccacaa
    12361 gtgttgcaac ctcaaatggc ctttcttacg ctccaaacca tgcctacaat ccaatgaatg
    12421 cagggcttca accacaaaca gcagccttca aagaagaagt ggcttctgcc tttggtatta
    12481 cgtcatttag tggttaccgt ccaggtgatc caggagatca tggtaaaggt ttggccattg
    12541 attttatggt gcctgaaaat tctgctcttg gtgatcaagt tgctcaatat gccattgacc
    12601 atatggcaga gcgtggtatt tcatacgtta tttggaaaca gcgattctat gcgccatttg
    12661 caagtattta cggaccagcc tacacatgga accccatgcc agatcgcggc agtattacag
    12721 aaaaccatta tgatcatgtt catgtctcct ttaatgctta attcatgcta ttaaaaaaac
    12781 tcacgtttag gcgtgagttt tttgacaatt ctgacagagt aagccctata agaggctgag
    12841 atacgctttt aatacctgtt gtttttctca ccctttagac agttttaacg ttatgtctaa
    12901 aagagatggt ttttattagc gcaaatatgg gtttaggggt aaaataaagg taattaacct
    12961 gatatgatca tgataaaggt agaagaatac ctattatttc gtgacaactg agcaatctgc
    13021 cttacctttg gagtgatgat atcactttgc ttgactattc aaggaggtct tgaaatgtat
    13081 tatactagtg gtaattacga agcttttgca acacctcgaa aacctgaagg ggtagatcag
    13141 aaatcagctt atattgttgg tactggttta gctggtttag cagcagctgt tttccttatt
    13201 cgcgatgggc atatggctgg ggaacgcatt catctgtttg aggaattgcc tttagcaggt
    13261 ggttctttag atggtattga aaagcctcat cttggttttg tgacccgtgg tggtcgtgag
    13321 atggaaaatc attttgagtg tatgtgggac atgtatcggt ctattccctc actggaaatt
    13381 cccggtgcgt cttatttaga tgaattttat tggttggata aggatgatcc taactcatcc
    13441 aactgtcgtt tgattcacaa gagaggaaat cgtgtggatg atgacggcca gtatacgctc
    13501 ggtaaacagt caaaagaatt aatccattta atcatgaaga cagaagaatc tctaggagac
    13561 caaaccattg aagagttctt ctcagaagat ttctttaaga gtaatttttg ggtgtattgg
    13621 gcaaccatgt ttgcttttga aaaatggcat tctgctgtag aaatgcgacg ctatgcgatg
    13681 aggtttatcc accatattga tggtttgcca gatttcacct ccctcaagtt caacaaatat
    13741 aaccaatatg actctatggt caaaccgatt attgcttacc tagaatcaca cgacgttgac
    13801 atccaatttg acacaaaagt cactgatatt caggtggagc aaacagctgg taaaaaggta
    13861 gcaaaaacca tccatatgac ggtgtctggg gaggctaagg cgattgagct aacacctgat
    13921 gatttggttt ttgtgaccaa tggttctatt actgaaagca gcacatacgg tagtcatcac
    13981 gaagtggcta agccaaccaa agcgttaggt ggttcttgga atttatggga aaatctagct
    14041 gctcaatcag atgattttgg tcatcctaaa gtgttttacc aggacttgcc tgctgaaagc
    14101 tggtttgtgt ctgctacagc aaccataaaa cacccagcta tcgagcctta tatagaacgt
    14161 ttgacccacc gtgacttgca cgatggcaaa gtgaacactg gcggcatcat cactattaca
    14221 gattctaact ggatgatgag ctttgccatt caccgtcaac ctcattttaa agaacaaaaa
    14281 gaaaatgaga ccactgtctg gatttacggt ctttattcca atagtgaggg caattacgtc
    14341 cacaagaaaa ttgaggagtg tacaggtcaa gaaatcacag aagaatggtt gtaccacctt
    14401 ggggtacctg ttgataaaat caaggactta gcgagtcagg actatatcaa tacagttcct
    14461 gtttacatgc cttatattac gagttacttt atgccacgcg tcaaaggaga ccgtccgaaa
    14521 gttatcccag atggttcagt caacttggcc tttattggta actttgcgga atctccatct
    14581 cgagatacgg tctttacgac tgagtattct attcgtactg ccatggaagc agtgtatagc
    14641 ttcttgaatg tggaacgagg catcccagaa gtctttaatt cagcctatga tattcgtgaa
    14701 ttgctcaaag ccttttatta ccttaatgat aaaaaggcaa tcaaggatat ggatttgcca
    14761 attcctgcac tgattgagaa aatcggacat aaaaaaatca aggatacctt tatcgaagaa
    14821 ttgctcaaag atgctaatct tatgtaacat gccttagagt agttaaagct gataagttta
    14881 ggcttatcag cttttttgat gatttataga aaagtgataa aggaaaagtc tgacgtgaac
    14941 gtcacataag aatttaaaat ttgttataat gtaagcaata aagatgaaag aaagagggac
    15001 tctatttgca agagtattct attgacatta ccttaaccca tcctgatgat gttttagctc
    15061 tttttggtag caacgagcgt catttgaagc taatagaagc tcatttagga gttattgttc
    15121 acgcaagaac cgagcgagtc caagtgattg gtgatgatga agaagctgtg gaattggctc
    15181 gattgaccat caaagcccta ctggttctag tgggtcgtgg catggtggtc aacacatcag
    15241 atgtggtgac agctttatct atggcagaat ctcatcagat tgaccaattt atggcgcttt
    15301 atgaagaaga aatcattaaa gataactatg gtaaggcaat acgagtcaaa acattaggtc
    15361 aaaaaaccta tgttgatagt gtcaaacgtc atgatgtggt ttttggtgta ggacctgcag
    15421 ggacaggtaa aaccttctta gctgttacgc ttgcagtcac tgctctgaaa agaggacagg
    15481 taaagcgtat tattttgacg cgtcctgcgg tagaagctgg cgaaagccta ggttttttac
    15541 caggcgattt gaaagaaaag gtggatcctt acctcagacc tgtttacgat gccctttatc
    15601 acattttagg caaggaacaa accacacgcc tgatggaacg agatgtgatt gagattgctc
    15661 cgttagctta tatgcgaggt cgtactctgg atgacgcttt tgttatctta gatgaggctc
    15721 aaaacacgac catcatgcaa atgaagatgt ttttgacccg tcttggtttt aattctaaaa
    15781 tgattgtcaa tggagatacg agtcagattg acctccctcg aaatgtcaag tctggtttga
    15841 ttgatgctac tcagaaatta caaggcatta aacagattga ttttgtctat ttctctgcta
    15901 aggatgttgt ccgacatcct gttgtggctg atattatcaa ggcttatgaa acgtcctcag
    15961 aggagatgaa ggacttacta aaacctaagg ctagtgacgt tgaagctgat taccagccag
    16021 gcttgacaaa ataccctgtg atcggtcaag agcactaaga cttttacgat gatgtttaat
    16081 atggcctttt taaggaggat tctatggatg atttaaccaa agctattatg gcagatgagg
    16141 ctaatctctc ctataccgaa agaggtattt ttcctttata tgatgctcct caaacagcta
    16201 ggattattat tgttggccaa gctcctggaa tagtagctca aggaaccaaa ctttactgga
    16261 atgatcgtag tggcatccgc ttacgagact ggctaggtgt ggacaatgac accttttacc
    16321 actcaggatt gtttggcatt atccctatgg atttctatta tcctggtaag ggaaaatccg
    16381 gtgacttacc acctagagaa ggttttgcgg ctaagtggca cccgccatta agagcattga
    16441 tgccagaagt tgaattgacg attttggttg gtcgctatgc tcaggacttt taccttggta
    16501 acaaggctta caaaacctta actgaaacag tccgtcactt tgaggattac ttgccagact
    16561 attttccact tgttcatcct tctccaagaa accaattgtg gttagctaag aacccctggt
    16621 ttgagcagga tttattacct atcttgcaaa aacgtgtgga ggcaattcta accaaatagg
    16681 ccctgattta cctagcattc ccatttttaa ggggcttgtg gtataatggg taaataacaa
    16741 atgctgattg aaaggataag ggaaattatc tgtcagataa taatgggtgc ccaacatacc
    16801 aaatgaggtg ggcagccctt ccctaacaat taaccttatg tatatcgaga tgattgacga
    16861 aacgggacaa gtttcgcaag agattatgga gcaaacactt gatttgctca attttgctgc
    16921 tcaaaagacg ggcaaagaag aaaaagaaat gtctgtgacc tttgtgacca atgaaagaag
    16981 tcatgaactc aacttagaat accgagatac tgatcgtcca acagatgtga tttctctaga
    17041 atataagcca gaaacgccta ttttatttag tcaagaggat ttggctgctg atcctagttt
    17101 ggcagagatg atggcagagt ttgatgctta tattggcgaa ttgtttattt ctattgacaa
    17161 ggcgcgtgag cagtcccaag aatatgggca ctcttttgag cgtgaaatgg gatttttggc
    17221 tgttcatgga ttcttacata ttaatgggta tgatcactac acccttgaag aagaaaaaga
    17281 gatgtttacc ttacaggaag agattttgac tgcttatggc cttacacgac aataatacca
    17341 ccaaacggaa atggaaaaac agaaccatta cctcaagctt ggagtttgcc ttgacagggg
    17401 ttttcacagc ttttaaggaa gaacgcaatc tcagaagcca ccttttgtct gcctgtttag
    17461 cttgtgttgc tggtttattt tttagcattt cagccatcga atggttattt ttacttctag
    17521 ccattttttt ggtcattacc ttagaaattg tcaattctgc tattgaaaat gtagttgatt
    17581 tggctagtga ctatcacttt tctatgctag ctaaaaatgc caaggatatg gcagcaggtg
    17641 ctgttttgat gatttctggc tatgctgtct tgacaggact tattattttt attcctaaaa
    17701 tttggaatat tttcgttcat taaaaagaaa ggaatgggct atcctatgtg atgatggcat
    17761 aggagaataa ggaaaggaca agacggttaa gcttagtgac aagcttgatc tgaagcccta
    17821 ccgttaaagc ccgtaattat ctatgtttaa atcaggcttt gtagccattc ttggtcgtcc
    17881 aaatgttggc aaatccacct ttttaaatca cgtcatgggg caaaaaattg ccatcatgag
    17941 tgacaaggct cagaccaccc gtaataaaat tatgggcatt tacaccacag aaacagaaca
    18001 aattgtcttt attgatacgc caggtattca taaaccaaag accgcccttg gtgattttat
    18061 ggttgaatct gcttatagta ctttacgtga agttgagacg gttcttttca tggttcctgc
    18121 cgatgaaaag cgtggtaagg gtgacgacat gattatcgag cggctaaaag cagctaagat
    18181 tcccgttatt ttagtcatca acaaaattga taaggttcat ccagaccaac ttttggaaca
    18241 gattgatgac ttccatagcc aaatggattt taaagaagtg gtcccaattt ctgccctaga
    18301 aggtaataat gtgccaactt tgatcaagtt attaactgat aatcttgaag aaggtttcca
    18361 atattttcca gaagatcaga ttactgatca tccagaacgt ttccttgtgt cagaaatggt
    18421 tcgtgagaag gtactgcatt tgacgcaaca agaggttcca cattccgtag ctgttgttgt
    18481 cgaatccatg aagcgagatg aagagactga taaagtgcat atccgtgcaa ccattatggt
    18541 ggagcgcgat agccaaaaag gcatcatcat tggaaaacaa ggagccatgc tcaaaaaaat
    18601 cggaaaaatg gcgcgccgtg atattgaact catgttaggc gacaaggtct acttagaaac
    18661 gtgggtcaaa gtcaagaaaa actggcggga taaaaagctt gatttagctg attttggcta
    18721 taatgagaaa gaatactaac atagtaaagc gagatcatat gccacaagac tacatttctt
    18781 atatccgctc caaagttggg catgataaga ttattcttaa ctttgctggt gggattttga
    18841 ccaatgatga cggcaaggtg ctgatgcagc tgcgtggtga taagaaaacc tggactattc
    18901 ctggtggcac tatggaactg ggtgagagct ctttagagac ttgcaaacgt gagttcttag
    18961 aggaaaccgg aattgaggtt gaagctgttc gcttactgaa tgtttacact cattttgagg
    19021 aagtttatcc caacggtgat gctgttcaga ctattgtctt tatctatgaa ctaacggctg
    19081 tttctgatat ggctattgat aactttcata atgaggaaac gctcaagtta caatttttct
    19141 ctcatgagga gatagcagag ttagagagtg tctcagccaa acatcgcctg atgttagagg
    19201 aatattttag tgatagcttt gctatggggc attaagaact ctctaggaca gttggagtat
    19261 ttttggagat tggcttgtta aaaaaatttt tgaaagacga tattcgagag cttatgctct
    19321 ctttttttgc ttccaatttt tctgattaag tctgaataat tttgttaaat gttaacagga
    19381 ttttctttcc aattgatact agcagacatc aaacatttgt tttagagtta tgacgaattg
    19441 ccacctagcc atgcatgact taggcaagtt gaacctaact gtgacaatag acttgggagg
    19501 ggtgacaaga atcatttcct aaaagaattg atgaagtgcc tatccattat tcgaattgta
    19561 aagttcgtct aagtaaagtt gaatttggtc tcgaatggac cttaatgatt tatgacttgt
    19621 tgtgtcaata acaccaaaaa ctcgataatg atttttaaat atttcctcgt aattaatatg
    19681 atttccgatt agaataatat gagcatgagg ataacgcata cgtatttcgt ttagaaggtc
    19741 atatacttgc ttagatttaa aaaagtatga tttatgataa aataaacctg acatttgtat
    19801 ttataatcta agtttttccc actaataatt tgagttttta gaaagtatct cttgaggtaa
    19861 tagttaatat agatagatat catatatcct aaaagagaac gatgtcttgt aagtattttc
    19921 ga
//
LOCUS       DAUGQX010000035        19505 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUGQX010000035 DAUGQX010000000
VERSION     DAUGQX010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19505
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.035"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..183
                     /locus_tag="VIA51_001276"
     CDS             <1..183
                     /locus_tag="VIA51_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEQ8683219.1"
                     /translation="DSLTRQVKNIYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEW
                     IGDGIEHIENPLIEWI"
     gene            451..870
                     /locus_tag="VIA51_001277"
     CDS             451..870
                     /locus_tag="VIA51_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ8683220.1"
                     /translation="MSKAKAILKDLRNLDLYIASLIRRRDKIEASLLSSPKWSSDKVN
                     GGIKRKQDDVYVELIATAKDIEKKTAEAIRKQRELQNLIDSLENTDSQTILSMVYIDK
                     MTRWQVIDELNCSESTYFRLLRVATKELNNLTVNDSD"
     gene            979..1323
                     /locus_tag="VIA51_001278"
     CDS             979..1323
                     /locus_tag="VIA51_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEQ8683221.1"
                     /translation="MSQLRADKKGTHRVAFDRNKKKLLKAATVCGICGKPVDKSLKYP
                     HPLSAAIDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRNLP
                     QSRDWSSFAFKK"
     gene            1472..1828
                     /locus_tag="VIA51_001279"
     CDS             1472..1828
                     /locus_tag="VIA51_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683222.1"
                     /translation="MKKKCLICKKNFQAKTNRTLYCSEECRKKGNREKQRKLMKQKRA
                     EQRKEKKKVLNPNTDVTEKPKKIRNLAQHYKKLKKEILANESEFGFTGITLIEGIDVH
                     EENFVDLVMQKIKEQK"
     gene            1825..3093
                     /locus_tag="VIA51_001280"
     CDS             1825..3093
                     /locus_tag="VIA51_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8683223.1"
                     /translation="MNYMGMGYLRRKLALFKTGVDKRYRYYAMDDRDDTRSIVMPNNV
                     REMYRSVLEWTAKGVDSLADRIIFREFTNDDFNAWEIFKANNPDIFFDTAIQSALIAS
                     CCFVYIMPGAEDGLPKMQVIEASKATGILDPTTFLLTEGYAILESDSNGNPTLEAYFT
                     DKDIWYYPKKGKPYNIKNPTGHPLLVPIIHRPDAVRPFGRSRITKAGMYHQKAAKRTL
                     ERAEVTAEFYSFPQKYVLGMDPDAEPMEKWRATVSTLLEISKDEDGDKPTVGQFTTAS
                     MAPFMEHLKMYASLFAGGSGLTLDDLGFPSDNPSSVESIKAAHENLRAAGRKAQRSFS
                     SGFLNVAYIAVCLRDEFPYLRNQFMDTVIKWEPLFEADANMLTLVGDGAIKLNQAIPG
                     FMDADVIRDLTGVKGADKPIPAITEVTTDG"
     gene            3086..4579
                     /locus_tag="VIA51_001281"
     CDS             3086..4579
                     /locus_tag="VIA51_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683224.1"
                     /translation="MVDDVLPKLLKSVRQDFEKYFGESDVVTKAFAELQAKKVTYKTV
                     NEFAIEVGRLLSLALTGSVSSDKLPDGKMYYNIAKRLLDETMGRNYKLISGYAGDVQR
                     ILNENAQIGLKVQRPPLNRDKINRMVNRLDSENTFDDVKWLFGEPIVNFSQSIVDDTI
                     KANADLQYKTGMTPQVVRTESGNCCEWCREVVGTYSYPKVPKDVWRRHQRCRCTLDYD
                     PKNGKVQSAWSKIWRKKEKTQESIERVEKFKESALVESIKNDIAKLDMTKVGPSDIID
                     IGKRINYHFRVSEHIGDKEKLKEIFSNFREIGGEIPKNTWAKGSSKLVKDQLQEAFQN
                     YPTEWAAVPDGIGKKLKAIKRKRGYFDGYDEDLVIATNGTRKTTPYHEIGHMIELVNP
                     DLVRLEKAWVDKRTANEAEVRLKDIFPSSNYGIGEVTKKDDFISPYIGKYYSDAAEVF
                     TMGLQGIFVPEERFAKSFDKKTWKYDYKTINDDPEFLNFIIGLFVKV"
     gene            4585..4809
                     /locus_tag="VIA51_001282"
     CDS             4585..4809
                     /locus_tag="VIA51_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683225.1"
                     /translation="MEPKLHRQLRQKYDDAEKQYLEKFGEDSLDRVFFWEPDVYFDEW
                     KKVLPDATLELNKAINSGVAIGPDPENAIY"
     gene            4859..5038
                     /locus_tag="VIA51_001283"
     CDS             4859..5038
                     /locus_tag="VIA51_001283"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683226.1"
                     /translation="MNKISLNVEMTWENKDEFQQIMNKVNETKEAYEKALEAAENFVP
                     KMSCATKLNKGEGDE"
     gene            5031..5297
                     /locus_tag="VIA51_001284"
     CDS             5031..5297
                     /locus_tag="VIA51_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683227.1"
                     /translation="MNKRIKKKRKLERAIVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQSAIADIAIDVNYIKKNYKRKWGK"
     gene            5407..6822
                     /locus_tag="VIA51_001285"
     CDS             5407..6822
                     /locus_tag="VIA51_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ8683228.1"
                     /translation="MVTKTKTKLGNQRPTQSVNLHFAKSLAHEAINYYKKTGLSCYPW
                     QVNMLIPIMAIDENGLWVHQKYGYAIPRRNGKTEVVYIVELWALHKGLKILHTAHRIS
                     TSHASFEKVKKYLEMSGYVDGEDFISNKAKGQERIEFKASGAVIQFRTRTSNGGLGEG
                     FDLLIIDEAQEYTSEQESALKYTVTDSDNPMTIMCGTPPTMVSTGTVFEAYRKDCLKG
                     NKRYSGWAEWSVPEMVKINDVSSWYISNPSMGFHLNERKIEAELGEDEIDHNIQRLGY
                     WPSFNQKSVISEKEWAKLKVEQVPELKSKLFVGIKFGQDGNNVSLSIAARTSENKVFV
                     ETIDCLSVRNGTQWIINFLKSADIAKVVIDGASGQELLAQEMKDQGLKKPELPKVAEI
                     ITANMMWEQGIMQETICHSDQPSLTAVVTNCEKRQIGSNGGFGYKSLYDDRDISLMDS
                     ALLAHWICYTTKPKRKQRTSC"
     gene            6903..7364
                     /locus_tag="VIA51_001286"
     CDS             6903..7364
                     /locus_tag="VIA51_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8683229.1"
                     /translation="MSEFKVIETQEELDTIVKARIAREREKYQDYDQLKTRVEELETE
                     NSSLQTALNDAKSNTDSYTEEISTLKNQIADYEAANLRTKVALQYGLPIDLADRLQGD
                     DEDGLKVDAERLASFIKPSQPQPPAKSNEPNIDSNADANYRALVQGLSTED"
     gene            7389..8300
                     /locus_tag="VIA51_001287"
     CDS             7389..8300
                     /locus_tag="VIA51_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEQ8683230.1"
                     /translation="MGTETSKASLFDKHLVSDLINKVKGHSSLAKLSSQKPIPFNGSK
                     EFTFTLDSDIDVVAENGKKTHGGLSLEPVTIVPIKVEYGARLSDEFLYATEEEKIDIL
                     KAFNEGFAKKLARGIDLMAMHGINPRTKKASDVIGTNHFDSKVTQVVKFTESEDADAN
                     IEAAVNLIQGSEGVVTGLAMDTEFSTALAKVTNGEMGPKMYPELAWGANPDSINGLKS
                     SVNTTVGAGADEAESKDLVIIGDFESMFKWGYAKQIPMEIIKYGDPDNSGKDLKGYNQ
                     IYLRAEAYIGWGILDAKSFARVTKGEV"
     gene            8300..8500
                     /locus_tag="VIA51_001288"
     CDS             8300..8500
                     /locus_tag="VIA51_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683231.1"
                     /translation="MLYVNSKTGASFYSSVPVCGGDWTLVEQQTGEKAKTVAEIKRQL
                     DAAGIKYSSKAKKPELEALLPG"
     gene            8510..8932
                     /locus_tag="VIA51_001289"
     CDS             8510..8932
                     /locus_tag="VIA51_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage Gp19/Gp15/Gp42 family protein"
                     /protein_id="HEQ8683232.1"
                     /translation="MGNFATTDDVILLWRPLSVDELKRANALLKVVSDTLRMEADKVG
                     KDLDKTMVDKPYFVNVIKSVTVDIVARTLMTSTRGEPMAQESQSALGYTWSGTYLVPG
                     GGLFIKDSELKRLGLKKQRYGGIELYGEIERDNSCFSR"
     gene            8892..9230
                     /locus_tag="VIA51_001290"
     CDS             8892..9230
                     /locus_tag="VIA51_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683233.1"
                     /translation="MAKLKGITVALADKSISGKDPFGNPVTVDFDIKIENVLVAPATT
                     EDITNQLSLTGKKVEYVLAIPKGDEHDWENKEVRFFGKKWRTVGIPLEGIEELIPLDW
                     NKKVMVERYE"
     gene            9223..9459
                     /locus_tag="VIA51_001291"
     CDS             9223..9459
                     /locus_tag="VIA51_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683234.1"
                     /translation="MSKFKFKLNRAGVAELMKSSEMQQVLTTKATAIRERCGDGYVQD
                     IHVGKNRANAMVSTKTIKAKKDNSKNNTLLKAVR"
     gene            9460..9795
                     /locus_tag="VIA51_001292"
     CDS             9460..9795
                     /locus_tag="VIA51_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683235.1"
                     /translation="MIEVIIKKYLDEHLDVPSFFEHQEDEPARFIILEKTSGAKQNHL
                     LSSTFAFQSYAESLYEAALLNDKVKQVIEQLDVLPQVSGVHLNADYNFTDTATKRYRY
                     QAVFDINHY"
     gene            9807..10400
                     /locus_tag="VIA51_001293"
     CDS             9807..10400
                     /locus_tag="VIA51_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8683236.1"
                     /translation="MNKNDTKNVTSAKPKTGGAIYSAPLGTELPKDAKSELNTKFKNL
                     GYVSEDGVVNEDTRSSENIKAWGGDIVGAVQTEKEDKFTYKLIESLNVEVLKEVYGAV
                     NVTGDLSGGIQIKSNSKELEAHVIVVDMIMNGGILKRIVLPNAKVDEVGEIKYVDGEV
                     VGYETTLKCFPDKDGDTHREYIVKPGEANKKENSFEM"
     gene            10411..10674
                     /locus_tag="VIA51_001294"
     CDS             10411..10674
                     /locus_tag="VIA51_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683237.1"
                     /translation="MEILKGKTTSGFEYEIPKKRLKNFELVEAIAEEETDPTAVVKIV
                     NLLLGDAAKSLKEHVRDAEGIVDVEAIGVEIKEIFESQKDLKN"
     gene            10689..11060
                     /locus_tag="VIA51_001295"
     CDS             10689..11060
                     /locus_tag="VIA51_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5361 domain-containing protein"
                     /protein_id="HEQ8683238.1"
                     /translation="MIAKDDDALTCDLAETYGIYDYRQLPAYQVAVFAVGLRSNSRIK
                     MALSGETEALDTVLLAGIYDNTNLLFWSKTKDGQSGQNKPKSVVEAISGSKSQKANDV
                     ISFVSGEDFENARKQLLGGDG"
     gene            11060..13417
                     /locus_tag="VIA51_001296"
     CDS             11060..13417
                     /locus_tag="VIA51_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683239.1"
                     /translation="MATELGQAYVQIMPSARGISGAISKQLDPEARSAGLSAGSLIGG
                     NLVKMIGGAIAAAGIGKMISSALSAGADLQQSFGGIDTLYKGAETAVKGFAKEAYKAG
                     ISANTYAEQAVSMGASLKQSLGGDAVAAAKAANMAIMDMADNSAKMGTDITSIQMAYQ
                     GFAKQNYTMLDNLRLGYGGTKEEMKRLLSDAEKLPAAMGKKFDLSNYADVVEAIHLVQ
                     DNMGIAGVAAEEAKTTFSGSLAAMKSSFTNVMAGLSLGDDIRPALRGLAETTSNFLFG
                     NFIPMVANIFKGLPSAIGTFIGAAAPIITSQFQGLMSSLGISIDLSPITAKFAQIGQN
                     LQPVFNGLKTAFSQLPSFFTSIGSAVAPVIDTIISGLARLDFSGFEALISAILPALQA
                     GFSNFAAIVGPAISGVVDSFVGMWNAAQPLISILSDALMPVFQILGSFLGGVVKGALM
                     GVSFAFDAVKVAIQLVTPIIDLLVQGLNFVQPVLSVIAEWIGVAIGMFGNLGTAGQGL
                     SAFIKSAWTNIQTAISTAGTIISTVIDYIKLAFSGAGSAVGVLKNIFSLAWMAMGDAI
                     NVAKGIISSVINGIKSAFSSFSSLVSSVGSAVNGVIDSISSTIRGLANIDISGAGAAI
                     MNGFLNGLKSAWGAVKSFVSGIANWIAEHKGPISYDRVLLKPAGKAIMGGLNTSLIDG
                     FKEVKSNVSGMADDLASTMTGKSLSLGIDAKPSVTADDLLSSNISTKTTVGSATSDLS
                     LFFVKVLALLQDILDKNTDVYLDKEKVSAILYEEFAKIMAREGIV"
     gene            13414..14109
                     /locus_tag="VIA51_001297"
     CDS             13414..14109
                     /locus_tag="VIA51_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683240.1"
                     /translation="MIPKVIIDDFDTSSIPNCVLTGYDVGDILSPSFVENEAYGMNGT
                     SRELESYNESKPTIMWHLSTFDDAVNLINHLDGLSKKIEFWHIPNSIYYYDCLSVKIN
                     AVTMSSWRVTLKLALYPFRYAKGVSDVVIAGNGNINNAGNVFSEPKIVVEGTGKGTLT
                     IGKQVMELNLSGKATIECKHGQQCVYDAEGNVKNSIRIRGSFFEIQPGTQGIAVSGGI
                     TRTIISPRWRYKV"
     gene            14106..15974
                     /locus_tag="VIA51_001298"
     CDS             14106..15974
                     /locus_tag="VIA51_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683241.1"
                     /translation="MISIKDDNTPLVAAFEDEITQEANSDYKLNFKYPAKHEYRPLIK
                     KGIILEADDLHGSQLFRIFEITKRHGYINVYANQVADDNTMHDFVKPKVTTQQAFGLA
                     QQVKELDLQLKDPKSDLWGKIKFNNKAMLVEYANKEMSSAIAQSAEQILLQVKSIDDE
                     RYSKFEQTLNGIKQTVKSESVESARTQLASMFDSRISGLDGKYSRLSQTIDSLSSRLD
                     DGVGNYSTLSQKVSGIDLRVSNAANDVSRLSQTAQGLQSQITNANQNYSSLSQTVQGL
                     QTTVRDNQSNATSRINQLSNLISTKVSKGDVETTIAQSYDKIAFAIRDKLPASKMSGS
                     EIISAINLDRSGVKITGKNITLDGNSYISNAVIKDAHIANMDAGKINTGYLNANRIAT
                     EAITGEKIKMDYAFFNKLTANEGYFRTLFAKDIFATSVQSVTLSASKITGGVLAATNG
                     ASQWDLNNANMTFNRDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYRGSALYASI
                     GITSSGDGIDSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFSINRGFK
                     FRPHKMEKVLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVSRELNNYITKI"
     gene            15986..16423
                     /locus_tag="VIA51_001299"
     CDS             15986..16423
                     /locus_tag="VIA51_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ8683242.1"
                     /translation="MQLTIKNKDLNTLYRVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            16420..17037
                     /locus_tag="VIA51_001300"
     CDS             16420..17037
                     /locus_tag="VIA51_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8683243.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIIAAEDGAVIPQLVKKDLTG
                     TNDKDIITAVLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHMLTSGGKIDPDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEAFEYDKQTLEELESEAKVTVIKYADLVKQD"
     gene            17047..17322
                     /locus_tag="VIA51_001301"
     CDS             17047..17322
                     /locus_tag="VIA51_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683244.1"
                     /translation="MATELIFGVGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHAEQNKTLITMTEQIKNLTDDVKDLKDMMRGEIK"
     gene            17319..17546
                     /locus_tag="VIA51_001302"
     CDS             17319..17546
                     /locus_tag="VIA51_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEQ8683245.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            17662..18867
                     /locus_tag="VIA51_001303"
     CDS             17662..18867
                     /locus_tag="VIA51_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8683246.1"
                     /translation="MTFLDKIKQGCLDGWTTYKILPSLTAAQTILESGWGKHAPHNAL
                     FGIKADSSWTGKSFDTKTQEEYQAGVVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYQ
                     AVIGETDYKKACHAIKDAGYATASGYAELLIQLIEENDLQEWDEEAIVRKEKQMISSQ
                     CREVIEFFINLVNAGVGVDKDGFAGWQCTDVPCYAAKHWFGVDLWGNAIDLLDSAAAV
                     GWEVHRMPTDANPQTGAFFVQSVPYHQFGHTGVVIEDSDGYTMRTIEQNIDGNPDALY
                     VGAPARFNTRDFTGVTGWFYPPYQGDIVTQPVSTEPQTSDTIVETAKTGTFTLDVAEI
                     NIRRWPSLTSEVVGSYKQGDTISFDSEGYANGYYWISYVGGSGMRNYTAIGITDKDGN
                     IISLWGKLN"
     gene            complement(18937..19371)
                     /locus_tag="VIA51_001304"
     CDS             complement(18937..19371)
                     /locus_tag="VIA51_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683247.1"
                     /translation="MKRSKKASLLSVIVGMALAVIPIYIVNYDNELIVLLMSIFFNGI
                     IVSAFELIKTYDGLQEEYKKLTVDRWKNTILLAFNSLYFASILTNSLSNNLSTILSTN
                     RSDKVSAIFLTGCSILALLPFLLHRLIKREIEIENERKKLKK"
BASE COUNT         6532 a         3319 c         4285 g         5369 t
ORIGIN      
        1 gactctttaa caagacaagt taaaaacatt tattttttgc aaaatacaaa agacgacatg
       61 ctgagtttta gtgatattaa cgttatgcca aggactcaag atattgagcg agaatttaat
      121 gtcaaagagt ggattggtga tgggatagaa cacattgaaa atccactaat tgaatggata
      181 taaccaataa cggtatcacg cacgttcgac tcgtgcggtt ggtattgacc gaaattaaaa
      241 aatagaaacg agaacctcct tacaccaaaa caaaatctaa cgctggttat cggtcactgg
      301 ctattattta aggcgctaat actgacatcc tgcgcctgtg tcaaaataaa aaaaaggaag
      361 agagggcttt tctccacaaa aaagccagct cacagctgac tccttagtta ataatttgac
      421 aaatctatta tatcaaaaag gagctagtta gtgagcaaag ctaaggcaat tttaaaagac
      481 ttacgcaatt tagatttata tatcgctagt ttaatcagac gtcgagataa gattgaggct
      541 tcgttgcttt ctagccctaa atggtcgtct gataaggtga atggtggtat aaaacgtaag
      601 caagatgatg tttacgtaga gttgattgca actgccaaag atattgaaaa gaagactgct
      661 gaagctataa gaaaacaaag agagcttcaa aacctgattg atagccttga aaatacagac
      721 agtcaaacga ttttgagcat ggtctatatt gataagatga ctagatggca agtgattgat
      781 gagctaaatt gcagcgaaag cacctatttc agactgttaa gagttgcaac taaggaatta
      841 aataatttga cagtaaatga cagcgattga cagtgaataa cagtgcatga cagttttaaa
      901 gtgataatat agtattatca agaaatgagg gacaggtaag aaaatacccc cctcttttaa
      961 atttagaaag gcccatccat gtctcagtta agggcagata aaaaaggtac ccaccgggta
     1021 gcatttgaca gaaataaaaa gaagttacta aaggcagcca ctgtctgtgg tatctgtggc
     1081 aagccagtgg acaagtctct taagtatcca catccattaa gcgcagcaat agatcatata
     1141 gttcctatcg caaaaggtgg tcatccatca gcgcttgaga acttacagtt aactcactgg
     1201 cagtgcaaca ggcagaagtc tgataagttg tttgctaacc aagcaagcaa cgagccaaag
     1261 acaattggca acagaaacct tcctcaaagt cgagactggt catcttttgc atttaaaaag
     1321 tgattttagg caaatatatt gatttatact aaaagctctt agaagcgaaa tggggggtat
     1381 ctccctaccc ggtcggtcgg ccgagcttca cgccgtcact gtacattttt tctcacgtta
     1441 ggatttagaa aattttggag gttgaatttc attgaaaaag aaatgcttaa tttgcaaaaa
     1501 aaacttccaa gcaaaaacca atagaacttt atattgctct gaagaatgcc gtaagaaagg
     1561 caatcgtgag aaacaacgta aattgatgaa acaaaaacgg gctgaacaga ggaaagaaaa
     1621 aaagaaagtc ctaaatccta acacagatgt gacagaaaag cctaaaaaaa tacgtaattt
     1681 agcgcagcac tataaaaaac taaaaaagga aattttggca aatgaatctg aatttggttt
     1741 tactggaata acacttattg aaggaataga tgtacatgaa gaaaactttg tagatttagt
     1801 catgcaaaaa ataaaggagc agaaatgaat tatatgggta tgggctatct tcgtaggaag
     1861 ttagctcttt ttaaaactgg agttgataaa agatatcgtt attatgccat ggatgacaga
     1921 gacgacacac gaagtattgt catgccaaat aatgtgcgtg aaatgtacag gtctgtgtta
     1981 gaatggaccg ctaaaggggt tgatagcctt gcggaccgta ttattttcag ggagtttacc
     2041 aacgatgatt ttaatgcttg ggaaattttt aaagcgaata accctgatat cttttttgat
     2101 acagccatac agtcagcatt aattgcatct tgttgctttg tgtacatcat gccaggagcg
     2161 gaagacggct tacctaaaat gcaagttatc gaagctagta aagcgacggg gatacttgac
     2221 ccaactacat ttttattaac agagggttat gcaattttag agtctgactc aaacggtaat
     2281 cctacgttag aggcctattt cacagacaaa gacatctggt attatccaaa aaaagggaaa
     2341 ccatataata ttaaaaatcc aacaggtcac cccttgcttg tacctatcat tcacagacca
     2401 gacgcagtta gaccatttgg tcgcagtcgc attaccaagg ctggaatgta tcatcaaaag
     2461 gcagcgaaga gaacgcttga gagagcagag gttacggctg agttttactc attcccacaa
     2521 aaatatgttt tgggaatgga tccagacgct gaaccgatgg aaaagtggcg tgctacggtg
     2581 tcaacgttac tcgaaatctc aaaagacgag gatggcgaca agccaacagt tgggcaattc
     2641 acaacagcaa gcatggcccc tttcatggaa cacttgaaaa tgtatgcttc gctatttgct
     2701 ggtggttccg gtctcactct tgatgacctt ggttttccat ctgacaaccc atcgtctgtt
     2761 gagtcaataa aagcggcaca tgagaatttg agagcagcag gacgcaaagc tcaacgttct
     2821 ttttcttctg gatttctaaa tgtggcgtat attgctgttt gtttaagaga tgaatttcct
     2881 tatcttcgta atcaattcat ggatacagta attaaatggg agcctctctt tgaagctgat
     2941 gcaaatatgc taactttagt aggggatgga gctatcaaac ttaatcaagc tatccctggt
     3001 ttcatggatg cagatgttat ccgtgattta acgggagtaa aaggggctga taaacctata
     3061 cctgctatca cggaggtaac aactgatggt tgatgatgtc ttacctaagc tactaaaatc
     3121 tgttcgacaa gattttgaaa agtattttgg cgaaagtgat gttgtaacca aggcttttgc
     3181 agaattgcaa gctaaaaaag tgacctataa aacagtcaat gagtttgcta ttgaagtcgg
     3241 aagactttta tctttggctc tgacaggttc tgttagctcg gataaattac cagacggtaa
     3301 aatgtattac aatatcgcta agcgtctctt agatgagact atggggcgga attacaaatt
     3361 gatttcaggt tatgctggtg atgttcagcg gattttaaat gagaatgctc agattggtct
     3421 aaaggtgcaa cgtccaccgc taaatcgaga caagattaac aggatggtaa atcgtttgga
     3481 tagcgagaat acatttgatg atgtaaaatg gctgtttggt gaaccgattg ttaatttttc
     3541 gcagtccatt gtggatgata ccatcaaggc aaatgcggat ttacaatata aaacaggtat
     3601 gacgccacag gttgtcagaa cagaaagtgg caactgttgt gaatggtgtc gtgaggttgt
     3661 tggcacttat agttatccaa aagtccctaa ggacgtatgg agaagacatc agcggtgtcg
     3721 atgtacgctt gactatgacc cgaagaatgg aaaagttcag agtgcttgga gtaaaatctg
     3781 gcgaaagaaa gaaaaaactc aagaatctat agaaagggtt gaaaaattta aggaaagtgc
     3841 tctagtagaa tctatcaaaa atgatatcgc taagttagat atgacaaagg ttggtccgag
     3901 tgatataatt gatataggga aacgtatcaa ttatcacttt agagtttcag aacatatagg
     3961 agataaagag aaattaaaag aaattttctc aaattttcgt gaaatcggtg gagaaatacc
     4021 taaaaatact tgggcaaaag gttcatctaa acttgttaaa gaccagctac aagaggcttt
     4081 tcaaaattat ccaactgagt gggcagctgt tccggacggt attggtaaaa aactaaaagc
     4141 tataaaaagg aagcgcggtt acttcgatgg atatgatgaa gatttagtta ttgctacaaa
     4201 tggaacaaga aaaacaacac cttaccatga gataggacat atgattgaac tggttaatcc
     4261 tgatttagta agattagaga aagcctgggt agataaaaga actgctaatg aagctgaggt
     4321 tcgcttgaaa gatatttttc caagttcaaa ttatggtatt ggggaagtta ctaagaaaga
     4381 tgactttata tcaccatata ttggtaaata ctacagcgat gcagctgaag ttttcactat
     4441 gggattacaa ggtatttttg ttcctgaaga acgatttgct aagtcctttg acaaaaaaac
     4501 atggaaatat gactacaaga caatcaatga cgaccctgaa tttttgaatt ttattattgg
     4561 attatttgtg aaagtgtgat aaatatggaa ccaaaattac atcggcaact gcgtcaaaaa
     4621 tatgacgacg ctgaaaaaca atatcttgaa aagtttggag aagactcgct tgatagagta
     4681 tttttttggg agccagacgt ttactttgat gagtggaaaa aggttctacc agatgcaaca
     4741 ctggaattaa acaaagctat taatagcggg gtggcgattg gtccagatcc agaaaacgca
     4801 atatattaag cacctagagc aatctggtgc ttttcttatg cccaaaaagg agaaaaatat
     4861 gaataaaata tcattaaatg tcgaaatgac ttgggaaaac aaagacgaat ttcaacaaat
     4921 catgaataaa gtcaatgaaa caaaagaagc ttacgaaaaa gccttagaag ctgcggaaaa
     4981 ttttgtccct aaaatgtcgt gtgcaacaaa gttaaataaa ggagaaggcg atgaataagc
     5041 gaatcaaaaa gaaacgtaaa ctcgaacggg ctattgtgat gctggttgcg gaaaatgcta
     5101 tgcaagcaga agcaattaaa aatcaaaaca aagaaatcat ggagctaaaa tcaatcgttc
     5161 aacgaaacgc tctggcaaca aacgaagagt ttgcgtctgt taaagctgct actttagata
     5221 accaatcagc tattgcagat attgcaattg acgttaacta tattaagaaa aattacaagc
     5281 gaaaatgggg aaaataaatt ttaaacgaat tcgacccctt tagaaatcaa agtcgtagca
     5341 atacggcttt ttattgtgcc ctgtcgcatg gctaaaaact aggcagtacg attgaaagga
     5401 ataagtatgg ttactaagac gaaaacaaag cttggcaatc agcgacctac tcaatcggta
     5461 aatttacatt ttgctaaatc tctagcgcat gaagctatta attactacaa aaaaacaggg
     5521 ctaagctgct atccatggca agtaaatatg cttatcccaa ttatggccat agatgaaaat
     5581 ggtctgtggg ttcatcaaaa gtatgggtat gctatcccac ggcgtaacgg taagacggaa
     5641 gtagtctata ttgttgagct gtgggctttg cataaaggtt taaaaatctt gcatacagct
     5701 catcgaatta gcacatctca tgcatcattc gaaaaggtaa aaaaatacct tgagatgtca
     5761 ggttatgttg atggagaaga ctttatatca aataaagcca agggtcaaga gcgtatagag
     5821 ttcaaagcca gcggcgctgt tatccagttc cgaactagga catcaaacgg tggacttggt
     5881 gagggatttg acttacttat cattgacgag gcacaagaat acacatctga gcaagaatca
     5941 gcattgaagt acacagttac tgatagtgat aatccaatga ctattatgtg tggaacgccg
     6001 ccaacgatgg tatctactgg tacagtattt gaagcatatc ggaaagattg cttaaaaggc
     6061 aataagcgtt attctggttg ggctgaatgg tcagttcctg agatggttaa gattaacgat
     6121 gtatcttcct ggtatatttc caacccatct atgggattcc acctcaacga gaggaaaatc
     6181 gaagctgaat taggtgaaga tgagattgat cacaacatcc aacgcttagg ttattggcca
     6241 tcctttaacc aaaaatcagt tatatccgaa aaagaatggg caaaactcaa agttgagcaa
     6301 gtgccagaac tcaaaagcaa gctttttgtc ggtatcaagt ttggtcaaga tggcaacaac
     6361 gtatcactat caattgcagc aagaacatca gaaaataagg tatttgttga gactattgac
     6421 tgtttatcgg tcagaaatgg aactcaatgg attattaatt ttttgaaatc ggctgatatc
     6481 gctaaggttg tcattgatgg tgcaagtggt caagaattac ttgctcagga gatgaaagat
     6541 caaggtctaa agaaaccaga attgcctaaa gttgctgaaa ttatcacagc taacatgatg
     6601 tgggagcagg ggatcatgca ggaaaccatt tgtcatagtg atcagccatc tttgacagca
     6661 gtagtcacaa actgtgaaaa gaggcaaatt ggctctaatg gtggttttgg gtataaatcg
     6721 ctttatgatg atagagacat tagcttaatg gacagtgcat tgcttgcgca ctggatttgt
     6781 tacacaacga agccaaaaag aaagcaaaga accagctgtt aaaaaacgac atccgaaagg
     6841 gtgttttttt actgctaaaa aatctaccga actgccggga aagcaggaga aaggacgtta
     6901 atatgtcaga atttaaagtt attgaaacac aagaagagtt ggacacgatt gtgaaagctc
     6961 gcattgctcg agaacgtgag aaatatcaag attacgacca actgaaaact cgtgttgaag
     7021 aactagaaac cgaaaacagc agcttacaaa ctgctttgaa tgatgctaaa tcaaacactg
     7081 atagctatac ggaagagatt agcaccctga agaatcaaat tgccgattat gaggcggcaa
     7141 atttacggac aaaggtagcg ttacagtatg gcttaccgat tgatttagct gatcgtttgc
     7201 aaggagatga tgaagatgga ctcaaagtag atgcagaacg cttagcatcc tttattaagc
     7261 catcccaacc acaaccgcca gcaaaatcaa acgaaccaaa tatcgatagt aatgcagacg
     7321 caaattacag agcgttagtg caaggattaa gtacagaaga ttagaagatt aattaaagga
     7381 gaaaaaatat gggaacagaa acatcaaaag cgagcttatt tgacaaacat ttagtatcag
     7441 atcttatcaa taaagttaag gggcatagct cactagctaa actatctagc caaaaaccta
     7501 ttccgtttaa cggatctaaa gaatttacgt ttacattaga ttctgatatt gatgtggttg
     7561 ctgaaaacgg taaaaaaaca cacggtggct tatcgctaga gcctgttact atcgtaccaa
     7621 tcaaggttga gtatggtgct cgtctttctg atgaattttt atatgcaaca gaagaggaaa
     7681 agattgatat tttgaaagct tttaacgaag ggtttgcgaa aaaactcgct cgtggtattg
     7741 acctaatggc gatgcatggt atcaatccac gtacaaaaaa agcgtctgac gttatcggca
     7801 cgaatcactt tgatagtaaa gtgacgcaag tggttaaatt tacagagagc gaagacgctg
     7861 atgcaaatat cgaagcagct gttaatctaa ttcaggggtc tgaaggtgta gtgacagggc
     7921 ttgcgatgga tacagagttt tcaacagcac tggcgaaagt taccaatggg gagatggggc
     7981 ctaaaatgta ccctgaactt gcttggggag cgaatccaga tagcatcaat ggcttgaaat
     8041 cgtccgtcaa tactactgtt ggtgctggag ctgatgaagc agaatccaaa gatttagtaa
     8101 ttattggcga ttttgaaagc atgtttaagt ggggttatgc aaaacaaatt ccaatggaaa
     8161 tcattaaata cggtgatcct gataattcgg ggaaagacct taaagggtat aaccaaattt
     8221 acttacgtgc tgaggcgtat atcggctggg gtattttgga cgctaagagc tttgctcgtg
     8281 tcactaaagg agaagtataa tgttatacgt taacagtaag actggagcta gtttttatag
     8341 ctccgtccct gtttgtggtg gagattggac tttggttgaa cagcagacag gcgaaaaagc
     8401 aaaaacagta gcagaaatta aacgtcagtt agatgctgct gggataaaat atagctctaa
     8461 agctaagaaa cctgaattag aggcactctt gcctggttag gaggtaaaag tgggcaattt
     8521 cgcaacaaca gatgacgtca ttttgttatg gcgtccctta tctgttgacg aattgaaacg
     8581 tgcaaatgca ctcttgaaag tcgtatcaga tacattaaga atggaagctg acaaagttgg
     8641 caaagactta gataaaacga tggttgataa gccttatttt gttaatgtta ttaaatcggt
     8701 tacggttgac attgtagcga gaacgctgat gacatctact cgaggcgaac caatggccca
     8761 agagagccaa tcagctttag gatacacatg gtcaggcact tatttagttc caggcggcgg
     8821 tctttttatt aaggacagtg agttgaagcg tcttggacta aaaaaacaac gatatggagg
     8881 aattgaactt tatggcgaaa ttgaaaggga taacagttgc tttagccgat aagtcgatta
     8941 gcggaaaaga cccttttgga aatcctgtaa cagttgattt tgatatcaaa attgagaatg
     9001 tgcttgttgc accagcaact accgaagata tcactaatca gttatctttg accggaaaaa
     9061 aggttgaata tgtcttggct ataccaaaag gagacgaaca cgattgggaa aataaggaag
     9121 ttagattttt cggcaaaaaa tggcgcacag taggaattcc actagaaggt attgaagagc
     9181 ttataccact agactggaat aagaaagtta tggtggaaag atatgagtaa gtttaaattc
     9241 aagcttaata gagctggtgt tgccgaattg atgaaatcat cagaaatgca gcaggtatta
     9301 accactaagg ccacagccat cagagaacgt tgtggtgatg gttatgtcca agatatccat
     9361 gttgggaaaa atagggctaa tgctatggtc agtactaaaa ccataaaggc caagaaagat
     9421 aactcaaaaa ataacacact gttgaaggcg gtgcgatgat tgattgaagt aattatcaaa
     9481 aaatatttag acgagcactt agatgtgccg tctttttttg aacatcaaga agatgaacct
     9541 gcacgattca tcatcttaga aaagactagt ggggctaagc aaaatcattt gctaagttcc
     9601 acgtttgctt ttcaaagtta tgccgaatcg ttgtatgagg cggctttact taatgacaaa
     9661 gtaaagcaag taattgagca gcttgatgtc ttgccacaag tttctggtgt acatcttaac
     9721 gctgactaca attttacaga tacagcaact aagcgctatc gttatcaagc tgtatttgat
     9781 attaatcatt attaaaggag atattgatga ataagaatga tactaaaaat gtaacatctg
     9841 caaagcccaa gaccggtggg gcgatttatt cggcaccgct tggtactgaa ttgcccaagg
     9901 atgcaaaatc agaattaaat actaaattta agaatttggg ttatgtatcc gaggatggtg
     9961 tggtcaatga agatacacgt tcatccgaaa atattaaagc gtggggtgga gatattgtcg
    10021 gggctgtaca gacagaaaaa gaggataaat ttacttataa gctgattgag tcactaaatg
    10081 tagaagtctt aaaagaagtt tatggcgctg tcaatgttac tggagattta agtgggggaa
    10141 tccagattaa atcaaattca aaagagttag aagctcacgt aattgttgtt gacatgatca
    10201 tgaatggcgg cattcttaaa cgaattgtct taccaaatgc aaaagtcgat gaggtaggtg
    10261 aaattaagta tgttgacggc gaagtcgttg gttatgaaac aacactaaaa tgtttcccgg
    10321 acaaggatgg tgatacacac cgtgagtata ttgtaaaacc tggagaagct aataaaaaag
    10381 aaaacagctt tgaaatgtaa aggggagtaa atggaaatct taaaaggaaa aacaacatca
    10441 ggatttgaat acgaaattcc taaaaaacga ttaaaaaact ttgaacttgt tgaagctatt
    10501 gcagaagagg aaactgatcc aacagcggta gttaaaatcg ttaatttgtt acttggtgat
    10561 gctgctaagt ctctaaaaga acatgtacga gatgcagaag gtatcgtaga cgttgaagct
    10621 atcggagtag aaatcaaaga aatttttgaa agtcaaaaag atttaaaaaa ctagcaatcc
    10681 tcgctcagat gatagcaaaa gatgatgatg cattgacttg tgatttagct gaaacatacg
    10741 gcatatatga ttacagacag ctacctgctt atcaggtggc tgtttttgct gtcggtttga
    10801 gatctaactc taggataaaa atggcattat ctggagagac tgaggctttg gatactgttt
    10861 tgttagctgg tatttatgat aatactaatt tgctgttttg gtctaaaact aaggatggtc
    10921 aatctggtca aaacaaacct aaatccgtgg tggaagctat atctggatct aaatcacaaa
    10981 aagctaatga tgtcatttct tttgtgtctg gcgaggattt tgaaaatgca cgtaaacaat
    11041 tactaggagg tgatggctaa tggcaacaga acttggtcaa gcgtatgtgc aaattatgcc
    11101 atccgctcgt ggaataagtg gagcaatctc gaagcaactt gatcccgaag caaggtcggc
    11161 tggattgagc gctggttcgc tcattggtgg taatctcgtt aaaatgattg gtggtgccat
    11221 tgcagctgct ggaatcggta agatgatttc gtctgccttg tccgctggtg ctgatttgca
    11281 gcaatctttt ggtggtattg acacattgta taagggcgct gagactgctg tcaaagggtt
    11341 tgctaaagag gcatacaaag ctggaatatc agcaaatact tatgcagagc aagcagtttc
    11401 aatgggtgca tctctaaagc aatcacttgg aggtgatgct gtcgcggctg ccaaggctgc
    11461 taacatggca atcatggata tggccgacaa ctcggctaag atgggtactg atatcacatc
    11521 aatccaaatg gcttaccagg gatttgctaa gcaaaactat acaatgcttg ataacctaag
    11581 acttgggtac ggcggcacaa aagaagagat gaagcgtctt ttatcagacg ctgaaaagtt
    11641 acctgccgct atgggcaaga agtttgattt gagtaattat gctgatgtgg ttgaggctat
    11701 acacttggta caggataaca tgggtatcgc tggagttgct gctgaagaag caaaaactac
    11761 attttcaggc tcactagctg ctatgaagtc ctcttttaca aatgtaatgg caggtttatc
    11821 actaggagat gatatcagac cggctttacg aggactggct gagacaactt ctaatttctt
    11881 atttggtaac tttattccga tggtggcaaa tatctttaaa ggattaccat cggcaattgg
    11941 tacttttatt ggagccgcag ctcctattat cacaagtcaa ttccaaggtc taatgagtag
    12001 ccttggaatt agtattgatt taagtcctat tactgctaaa tttgcacaga ttggccaaaa
    12061 tttacaacct gtttttaacg gtttaaaaac ggcttttagt cagttgccat cattttttac
    12121 tagcattggt agtgcagttg caccagtaat agacactatt attagcggat tagccagatt
    12181 agatttcagt ggttttgagg ctttaatttc agcaatttta ccagccctac aggcaggttt
    12241 ttctaacttc gctgcgattg ttggaccagc tatctcagga gttgttgact cgtttgttgg
    12301 catgtggaat gcagcacaac ctttaatttc gatactaagt gatgccttga tgccagtatt
    12361 tcaaatttta gggtctttct taggtggtgt tgtaaaaggt gcgcttatgg gagttagctt
    12421 tgcctttgat gcagttaaag tggctataca actagtcaca ccaattattg acttgctggt
    12481 tcaaggtctt aattttgtac aacctgttct cagtgtcatt gcagaatgga ttggagttgc
    12541 tatcggtatg tttggtaatt taggcacagc cggccaaggc ttgagcgctt ttattaagag
    12601 cgcttggact aacattcaga ctgcaatttc aactgctgga acaatcatat ctacggttat
    12661 tgactacata aaattagcgt tcagtggtgc cggttctgca gttggcgtcc taaaaaacat
    12721 tttctcactt gcttggatgg caatgggaga cgcaataaat gtggctaagg gtatcataag
    12781 ctctgttata aatggcataa aatcagcctt cagtagtttt agtagcttag tgtctagtgt
    12841 tggttcagca gtaaatggag ttatcgattc aatctcaagc acaattagag gtttggcaaa
    12901 cattgatatt tctggagctg gtgccgcaat tatgaatggt ttcttaaacg gtttgaaatc
    12961 agcttgggga gccgtcaaaa gttttgtgag cggtatcgcc aactggattg cagaacataa
    13021 aggacctatc tcttatgata gagttctact aaaacctgct ggtaaagcaa ttatgggtgg
    13081 acttaataca agcttgattg acggctttaa agaggttaaa tcaaatgtct ctggcatggc
    13141 tgacgacctt gcaagcacca tgacaggtaa aagtctatct ctcggtatcg atgctaaacc
    13201 aagcgtcaca gctgatgact tactatcaag caatattagt actaaaacta cagtcggttc
    13261 tgctacaagt gacttgtcat tattctttgt taaggtgctt gctctgttgc aagatatcct
    13321 tgataaaaat acggatgtct atctagacaa agaaaaagtc agcgctattt tatacgaaga
    13381 atttgccaaa attatggcta gagaggggat tgtatgatac ctaaagttat tattgatgat
    13441 tttgacacat cttcaatccc taattgtgtt ttgaccggtt acgatgtggg ggatattcta
    13501 tcccctagtt ttgtcgaaaa tgaagcttat ggcatgaatg gaactagtag ggaattggag
    13561 tcatataatg aatctaaacc aaccataatg tggcatttga gtacttttga tgatgcagtt
    13621 aatctaatta atcatttaga cggccttagt aaaaaaatcg aattttggca catacctaac
    13681 tctatttatt actatgattg cttatctgtc aaaatcaatg cggtaaccat gtcatcatgg
    13741 cgtgtgactc tcaaacttgc tctttatcca tttagatacg caaaaggtgt ctcagatgta
    13801 gtaattgcag gcaacggaaa cattaacaat gcaggaaatg ttttcagcga acctaagata
    13861 gttgttgagg gtactggtaa aggaacgcta accattggca aacaggtcat ggaattaaat
    13921 ttgtcaggta aagcaacgat tgagtgcaaa catggccaac aatgcgtcta tgatgctgaa
    13981 ggtaatgtga aaaactcaat ccgaataaga ggaagttttt ttgaaataca acctggcaca
    14041 caaggtattg ccgtcagtgg aggcattact agaacaataa ttagtccaag gtggaggtat
    14101 aaggtttgat atcgattaaa gatgataata cccctcttgt agcagccttt gaagatgaga
    14161 ttacacagga ggccaatagt gattacaaac taaattttaa gtatcctgct aaacacgagt
    14221 atcgcccttt aataaaaaaa ggaataatct tagaagctga tgatctgcat ggttctcagc
    14281 tttttaggat ttttgaaatt actaagcggc atggctatat taacgtttac gctaatcagg
    14341 tcgctgatga caatacaatg cacgactttg taaagcctaa agttaccact caacaagctt
    14401 ttggactagc tcagcaggtc aaagagcttg atttacagct aaaagaccct aagtcagatt
    14461 tgtggggcaa aatcaagttc aataataagg caatgctagt cgagtacgcc aacaaagaga
    14521 tgtcaagtgc cattgcgcaa tcagctgagc agatattgtt acaagtcaag tctattgatg
    14581 atgaacgata ttccaaattt gagcaaactc tgaatggtat caaacaaact gtcaaaagtg
    14641 agtcagttga atccgcacgt actcagctag catcaatgtt tgatagtcgt attagtggac
    14701 ttgatggcaa atacagtcgt ttgagccaaa caattgatag tcttagcagt cgtcttgatg
    14761 atggtgttgg taactactca acgctatctc aaaaggtaag tggcattgat ttacgagtta
    14821 gtaatgcagc taatgatgtt tctcgattgt ctcagacagc acaaggattg cagtcacaaa
    14881 tcacaaatgc aaaccaaaat tacagcagtt tgtctcagac tgtacaggga ctacaaacaa
    14941 ctgtacgtga taatcaatca aatgctacaa gtcggattaa tcagttaagt aacctgatca
    15001 gcacaaaggt atcaaaaggt gatgttgaga caactattgc tcagagttac gacaagatag
    15061 ccttcgcaat cagggataaa ctcccagcaa gcaaaatgtc tggcagtgag attatctcgg
    15121 caatcaatct tgataggtct ggggttaaaa tcactggaaa aaatatcact cttgatggta
    15181 acagctacat cagcaacgct gtcatcaaag atgctcatat tgctaacatg gatgccggta
    15241 agattaatac tggttatctt aatgctaata ggattgcaac cgaggccatt actggtgaga
    15301 aaattaagat ggactatgcc ttttttaata aactcactgc taacgaggga tattttagga
    15361 cgttgtttgc caaagacatc tttgcaacat cagtccaatc tgtaacacta tcagctagca
    15421 aaattactgg aggtgtatta gccgctacaa atggggcaag tcagtgggac ctaaataatg
    15481 ccaatatgac ctttaatcga gatgccacaa ttaattttaa tagcaaaaac aatgccttag
    15541 tacgtaaaga tggcacacat actgcttttg tacattttag taatgccaca ccaaaaggct
    15601 atagaggctc agcgttatat gcctctatcg gcattacctc atcaggagat ggcatcgaca
    15661 gcgcttcttc cggtcgtttt gcagggctaa ggtcatttag gtacgctacg ggatataacc
    15721 atactgctgc agtcgaccaa accgagctat acggtgataa tgtcttgatt gcagatgact
    15781 ttagcatcaa tcgaggattt aaatttagac cacacaaaat ggaaaaagtg ctcgacatga
    15841 acgacttgta tgcggctgta gtagccttag gccgctgttg ggggcacttg gctaacgtcg
    15901 gctggaatac tgctcatagc aattttacaa gtgctgtgag tagggaattg aataactaca
    15961 tcactaaaat ttaacaggag ataatatgca attaactatt aaaaacaaag atttaaacac
    16021 actatatcgt gtactagaca aaatcaaagt cacgaacatg cgagcaaacc gcggacgtgc
    16081 taagctactc gcaaaagtag tagataaatt caaagagtac gccaaggatg agggtgacct
    16141 tattgatctg tatgctcaaa aagacaaaga tggcaagttt gtcattgatg agcacaaaaa
    16201 catcaagcta gcagaccccg ctaaactcga cgagttcaac ggcctactca acgagctagc
    16261 tgatgaagaa attgtgatta aagggggtga gtactccaag cgatttattg actttttaaa
    16321 ctttttagaa gagtgtgaag atgaatttac atcatctgaa atcattctta tcgacaacat
    16381 tttggaacaa tttgaagaaa gtaaaaaagg agaaaaacca tgagaaattg gaaagtgaca
    16441 ggaaaatacc cacaatttga cagcacagga gcagtcgcaa gtacacacgt cattatcgct
    16501 gcagaagacg gcgctgttat cccgcaactt gttaaaaaag atttaacagg cacaaatgat
    16561 aaagacatta tcacagcagt gctcgaagag tttaaaaaat ctgaatacgt tgaaattgca
    16621 atgggcgaag ccgtgcaaaa agtagacgac cttgaaaaaa tctcacagga aaccgctaag
    16681 actgccaaaa ctgctcaaac agctgctgga ctagctaagg tgtccgcaga gcgtacacag
    16741 cgaatgatta acttgcaaac catccacatg ttaacgagcg gcggcaagat tgatcctgac
    16801 atttataaag gcatgcttga gctaatcgag ccagccaaaa aaggtgagta tcaagcctat
    16861 gatgtcttta cggtggtcga cagtactaaa gaggaagacg gtgaagcagg cgaagggaac
    16921 ctagtctttg tacacgttaa tgaagcattt gagtatgaca aacaaacctt agaggagcta
    16981 gagtcagaag ccaaagtaac agttatcaag tacgctgatt tggttaaaca agattagagg
    17041 tgttttatgg caacagagtt gatatttggc gtcggtggct ttattttagc tatcgtcacg
    17101 acttacaata tttttaatgc aaaatccatc aagcatgcga cagatattac tttgttgcaa
    17161 tctgaggtag agcatttaaa aattgttaca cgccaaaatg ctcggcggct tgaagagcac
    17221 gctgagcaaa ataaaacgtt gattacaatg acagagcaaa ttaaaaattt aacagatgat
    17281 gttaaagatt taaaagatat gatgagagga gaaatcaaat gatcaattta aaattacgac
    17341 tacaaaacaa agtaaccttg atggctattt tgggagctat ctttttgtta gcgcaacaat
    17401 taggtattaa actaccatca aacatcgcgg atattgccaa cacagctgta acgcttttgg
    17461 tattgctcgg tgttgtcaca gatccaacca caaaaggcct gtcagacagt gagcaagcat
    17521 tgacttacca cgaaccaaaa caataggagg agccatgcga gcaatcacac gattagcatt
    17581 agttatagca atcgcaatac tgtatgtgcc gatatctgtt gttgctctga tcttttatcc
    17641 atttttagat aaggaggaca gatgaccttt ttagataaaa ttaaacaagg ctgtttagat
    17701 ggctggacaa cgtacaaaat cttgccatcc ttgaccgcag cgcagacaat cttagaaagc
    17761 gggtggggca aacatgcccc acacaacgct ctgtttggta ttaaggcaga tagctcttgg
    17821 actggtaaat catttgatac caaaacccaa gaggaatatc aagcaggtgt tgtcacggat
    17881 attgtggacc gatttagggc gtatgatagt tggactgaca gcattattga tcacggtaaa
    17941 tttttaaacg ataatccacg gtatcaggct gtgattggtg agactgatta caaaaaagct
    18001 tgtcacgcta taaaagatgc aggttatgcc acagctagcg gttatgcaga gttgcttatc
    18061 caactaatcg aggaaaatga ccttcaggaa tgggatgaag aggctattgt cagaaaggag
    18121 aagcaaatga ttagttctca atgtcgagaa gtcattgaat tttttattaa cttggtaaat
    18181 gctggggttg gcgtggataa agatggtttt gcgggctggc aatgcacaga tgtgccttgt
    18241 tatgcagcaa agcactggtt tggtgttgat ctttggggaa atgcgattga cttactagat
    18301 agcgctgctg ccgtaggttg ggaagtccac cgcatgccga cagatgcaaa tccacagact
    18361 ggagcatttt ttgtccaatc agtgccatat catcaatttg gtcacacagg agttgtcatt
    18421 gaggatagcg acggttatac catgcgaact atcgagcaaa acattgatgg caatcctgat
    18481 gctttgtatg tcggtgcacc agctcgtttt aatactcgtg attttaccgg cgtgacagga
    18541 tggttttacc ctccttacca aggagatatt gtcacgcaac cagtcagcac cgagccacaa
    18601 acgtctgaca ctatcgtaga gacagcaaaa acaggtactt ttacgcttga tgtcgcagaa
    18661 atcaatatca gacgttggcc aagtttaact agcgaggtag taggtagcta taaacaaggt
    18721 gatactatca gctttgatag tgagggttac gccaatggtt actactggat tagctacgtt
    18781 ggcggctcgg gtatgcgaaa ctacacggct atcgggataa ctgacaaaga cggtaacatt
    18841 atcagccttt ggggcaaatt aaattaggag ataaagctcc tttagataag acaaaaccgc
    18901 tctcttaatc gagggcggtt ttttgtgttt aagtaattat ttttttaatt tttttctttc
    18961 attttcaatt tctatttctc gttttattaa cctatgaagg aggaatggaa gtagtgctaa
    19021 aatagaacaa cctgtaagaa atattgcact tactttgtca gaacgattag ttgataaaat
    19081 ggtcgataaa ttatttgata gactatttgt caaaatagaa gcaaaatata atgaattgaa
    19141 agccagtaaa atagtattct tccatctatc tacagttagc tttttatatt cttcctgcaa
    19201 accatcatat gttttaataa gttcaaaagc ggaaacaatt atcccattaa aaaaaatact
    19261 cattaaaaga acgataagtt cattgtcata attaacaata taaattggta tcacagctaa
    19321 agccattcca acaataacac taagtaacga tgcttttttg gaccttttca taaaatcacc
    19381 cttttttttc aatctactat acatattact cgattcaatc atcctcaaca aaggccgtta
    19441 aaacagacta atttctcaaa gtcctattta agggactttc taaatagacg ttgttttttt
    19501 aaaaa
//
LOCUS       DAUGQX010000036        19077 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUGQX010000036 DAUGQX010000000
VERSION     DAUGQX010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19077
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.036"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            263..784
                     /gene="pyrR"
                     /locus_tag="VIA51_001305"
     CDS             263..784
                     /gene="pyrR"
                     /locus_tag="VIA51_001305"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEQ8683248.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            800..2059
                     /locus_tag="VIA51_001306"
     CDS             800..2059
                     /locus_tag="VIA51_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEQ8683249.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            2120..3055
                     /locus_tag="VIA51_001307"
     CDS             2120..3055
                     /locus_tag="VIA51_001307"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEQ8683250.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            3099..4181
                     /gene="carA"
                     /locus_tag="VIA51_001308"
     CDS             3099..4181
                     /gene="carA"
                     /locus_tag="VIA51_001308"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEQ8683251.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            4407..7583
                     /gene="carB"
                     /locus_tag="VIA51_001309"
     CDS             4407..7583
                     /gene="carB"
                     /locus_tag="VIA51_001309"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEQ8683252.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSPLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            7790..9061
                     /locus_tag="VIA51_001310"
     CDS             7790..9061
                     /locus_tag="VIA51_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8683253.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGIVLWKQQRNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNRDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGATYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            9061..9771
                     /locus_tag="VIA51_001311"
     CDS             9061..9771
                     /locus_tag="VIA51_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683254.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            9783..11003
                     /locus_tag="VIA51_001312"
     CDS             9783..11003
                     /locus_tag="VIA51_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683255.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGKGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            11257..12990
                     /locus_tag="VIA51_001313"
     CDS             11257..12990
                     /locus_tag="VIA51_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEQ8683256.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTIVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            13117..13389
                     /gene="rpsP"
                     /locus_tag="VIA51_001314"
     CDS             13117..13389
                     /gene="rpsP"
                     /locus_tag="VIA51_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEQ8683257.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            13399..13638
                     /locus_tag="VIA51_001315"
     CDS             13399..13638
                     /locus_tag="VIA51_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEQ8683258.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            14549..17575
                     /locus_tag="VIA51_001316"
     CDS             14549..17575
                     /locus_tag="VIA51_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEQ8683259.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPSGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTLGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STIVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            17595..17996
                     /locus_tag="VIA51_001317"
     CDS             17595..17996
                     /locus_tag="VIA51_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEQ8683260.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(18176..19051)
                     /locus_tag="VIA51_001318"
     CDS             complement(18176..19051)
                     /locus_tag="VIA51_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEQ8683261.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCTLHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIEVN"
BASE COUNT         6285 a         3014 c         3808 g         5970 t
ORIGIN      
        1 tatctgttag agatctttat ttaaactcct taaagaaaag agatattcca aatagatgct
       61 aggtattgtc ttttttactt gtttttcttt tctttttttg ctatactgat tgaaataaaa
      121 tattccttta aaacagtcct gtgaggctgt caaggagacg gattaaaaac atgcatcatg
      181 atacttaatt gtgctatatt ttgctgaatc tccttgtttc caaggagatc tttttatttg
      241 aatttttaga ggaggtttca acatgaaaac taaggaaatt gttgatgacg tgaccatgaa
      301 acgcgccatt acccgtatta cttatgaaat tattgaacgt aataaacaat tagacaatgt
      361 ggttttggca ggcatcaaaa cgagaggtgt ttttctagct cgtcgcattc aagaaagact
      421 gcatcaatta gaagggttgg atttaccaat tggtgagtta gacatcaagc cttttagaga
      481 tgacatgaga gttgaggaag acacaactct gatgtcagta gatattacag gcaaggatgt
      541 gattttgatt gatgatgtgc tttatactgg tcgtaccatc cgcgcagcca tcgataactt
      601 agtgagttta ggtcgaccag cccgtgttag tctagctgtt ttggtggatc gtggccatcg
      661 ggaattaccg attcgcgcgg attacgttgg gaaaaatatt ccaacaagca gtgtagaaga
      721 aattgttgtt gaggttgtcg aagtcgatgg ccgtgatcgt gttagcatta ttgacccaac
      781 ataagaaaga ggttttactg tgaaagatgt catttatgat gtggaagaag tgccaaaggc
      841 aggtatgtta gttggtttgt cctttcagca cttatttgct atgtttggtg cgactgttct
      901 ggttcccatt ctagttggaa ttgacccatc agttgctttg ttatctagtg gtttaggaac
      961 ccttgcccac ttatcagtga ccaaatttaa aattccagcc tacatgggct caagttttgc
     1021 ttatatagca gctatgcagt tactgatgaa gacaaatggt attggtgctg tagctcaagg
     1081 ggctatgaca ggaggtctcg tttacctgat tgtagctttg attgttaaag ctattggcaa
     1141 tgattggatt gataacatct taccaccgat tgtggttggt ccgattgtta tggtcattgg
     1201 tctaagccta gcttctacag ctgttaatga tgtcatgcta aaaaatggga actataatct
     1261 gacttatctt gttattgggt tagtcacctt attatcagtt atttttttca atatttatgg
     1321 taagggaatt gttgctattg taccgctttt attagggcta ttagttggtt atgttgtagc
     1381 ccttttagtg ggtgttctca ccggtcaaga aattgttgat tttaccaatg tggctcaggc
     1441 caaatggttt agtatcccat cagtggaaat tcctttctta acctacgggg ttaaattcta
     1501 cccaagtgcc attttaacta tggcacccat tgcctttgtt acaatgacag aacattttgg
     1561 acacattatg gtcttaaata gtttgacaaa aagagattat ttcaaggatc caggacttga
     1621 aaagacttta actggtgatg gttttgcgca aatcattgcc ggcttcttag gggcacctcc
     1681 ggtcacttct tatggtgaaa acatcggtgt aatggctttg aataaaatat tctcggtcta
     1741 tgttattgca ggtgccgcag tgattgccgc tctcctcagt tttatcggta aggtatcagc
     1801 cttaattcaa tctattccaa caccagttat tggaggtata tcagttgcct tgtttggtgt
     1861 gatagcttct agcggtttga aaatcttgat tgaatccaaa gttgatatgg ataataagaa
     1921 aaacttattg attgctagtg ttattttggt ctctgggatt ggaggattga tgcttcaagt
     1981 aaatggtctt caaatttcag gtgtcgcttt ctcaacactc cttggcatca tcttatatca
     2041 ggtacttcct gaaaaatagg aagaattgtt gttagaccac ttacatagtc atcagtcgtt
     2101 agtgataaag gggataatca tgtcagttgt aaataatcgc gttgcactta ccaatttagt
     2161 ttcaatggaa gcattaacca ccgaagaagt tttaggtctt atcaaccgtg gttcagaata
     2221 taaggctggt aaagttgtta tttcggatca tcaaaaggat cttgttgcca atttattctt
     2281 tgaaaactcc acccgaaccc ataagtcttt tgaagtggct gagaagaaac tcggcttgac
     2341 agttcttgat ttcaatgctg atgcaagtgc ggttaacaag ggagaaagtt tgtatgatac
     2401 tgtgttaacc atgagtgcac ttggaacaga catctgtgtg attcgtcacc cagaagatga
     2461 ttattacaag gaattagtag aaagtccaac tattacagct tccattgtca atggaggaga
     2521 tggttctgga caacacccga gtcaatgttt acttgactta ttaaccatct atgaagaatt
     2581 tggacgcttt gaaggcttaa agattgcgat cgctggtgac ttaactcact ctagggtggc
     2641 aaagtccaac atgcaaatcc tcaaaagatt aggagcagag ctttatttct atggacctga
     2701 agaatggtat tcagaagcct ttaatgctta cggcacttat attgctattg accagattat
     2761 taaggaattg gatgttctta tgttgctgcg tgtacagcac gaacgtcatg acggccatca
     2821 gagtttttca aaagaaggtt accatcaagc gtttggattg acacaggaac gttaccaaca
     2881 attaaaagat tctgctatta ttatgcatcc agctccagtt aatcgggatg tggaaattgc
     2941 agatagtttg gtggaagctc ctaaagcgag aattgtatct cagatggcta atggtgtctt
     3001 tgttcgcatg gctattattg aagccatttt gaatggtaga aataaaaact catgatgaaa
     3061 gattaaagca tgtttagaag gtaggaaaag gtaggaaaat gacaaaacga ttacttattt
     3121 tagaagacgg cactattttt gaaggagaac cctttggtgc tgatattgat gtgactggtg
     3181 aaattgtctt taatacagga atgacaggct accaagaatc catcactgac caatcctaca
     3241 atgggcaaat tttaaccttt acctatcctt tgattggaaa ttatgggatt aatcgagatg
     3301 actatgagtc catttcaccc acctgtaaag gggttgttgt gtctgaagtc agtcggttgg
     3361 caagtaattg gcgcaagcaa atgacgctag atgcgttctt gaaaataaaa gggattccag
     3421 ggatttcggg aattgatacg agagctttga ccaaaattat tcggcaacac ggtaccatga
     3481 aagctacgat ggcagatgat ggagatagta tccagcattt aaaagatcaa ctgcgtgcaa
     3541 cagtcttacc gactaacacc attgaacaag tgtcaactaa aacagcttat cctgcaccag
     3601 ggatcgggaa aaatattgta ttggttgatt ttggtttaaa acattctatt ttaagagaat
     3661 tttctaaaag acaatgtaat atcaccgttg tccctttcaa catcactgca gaagaagtgc
     3721 tccaactaaa tccggatggc ttgatgctat ctaatggccc aggaaaccca gaagatttgc
     3781 cagaggcttt agacatgatt cgtggggtac aaggtaagat tcctattttt ggtatttgta
     3841 tgggacatca actctttagt ctagcaaatg gtgctaagac ttgtaaaatg acctttggtc
     3901 atcgtggctt taaccatgcc gttagagaaa ttgcaacggg aagaattgat tttaccagtc
     3961 aaaaccatgg ttatgccgtt gaacgtagta gtctacctga tactttaatg gttacgcatg
     4021 aagacattaa cgataagacg gtcgaaggag tgaaacatag agattttcca gctttttcag
     4081 tccaatttca ccctgatgcg gctccaggac ctcatgatgc cagctactta tttgacgaat
     4141 ttttggaaat gattgattct tggagatgta cgagtaaata gtaaatcagt tgcaatttca
     4201 cgactatatc acctcttgtt actctattta ttaacattta cagtaatatt atttaatgtt
     4261 gctctgtgag gcaacaaata gagaaaggaa ggcaaggaga acacaagtaa ataatttagt
     4321 aaaaagttag gttttcaaag agataaagct cttattgaga agtgctgact ttaccgcttc
     4381 ttgtggtatt cttggtatca ttaattatgc caaaacgaaa agatattcaa aaaatcatgg
     4441 ttatcgggtc tggcccgatt attattggac aagctgctga atttgattat gcagggactc
     4501 aggcctgttt ggctctaaaa gaagaaggct acaaagtcat acttgttaat tcaaatcctg
     4561 caacgattat gacagataaa gaaatcgctg ataaggtata tattgagcct ttgactcttg
     4621 aatttgttaa tcgtatcatt cgaaaagaaa ggccagatgc catactgcca accttaggtg
     4681 gccaaacggg cctcaatatg gcaatggcgt tatctaaagc tggtattctt gatgatttag
     4741 agattgaatt gttaggtact aagttatctg cgattgatca ggcagaagac agagaccttt
     4801 tcaaacaatt aatgcaagaa ctagaccaac ccattccaga atctacaatt gttaaaacag
     4861 ttgatgaagc tgttacattt gctagagata tcggttatcc agtcattgtg cgcccagctt
     4921 ttactcttgg tggaactggt ggaggaatat gtagtagtga agaagaactt tgtgaaatta
     4981 ctgaaaacgg cctaaagtta tcaccagtca cacagtgttt gattgaacgc tcaattgctg
     5041 gcttcaaaga aattgaatac gaagtaatgc gagatagtgc tgataacgcg ctggttgttt
     5101 gtaatatgga aaactttgat cccgtaggga ttcacacagg agattctatt gtatttgcac
     5161 caacacagac cctttctgat attgaaaatc aaatgttacg tgatgctagt ttaaaaataa
     5221 ttcgagctct gaaaattgaa ggtggctgta acgtccagtt agcactagat ccttatagtt
     5281 tcaaatatta tgttattgaa gtaaatccta gagtgtctcg ttcctctgcc cttgcttcaa
     5341 aagcaacagg ttatcccatt gccaaattgg ctgcaaagat tgctgttggc ctaacacttg
     5401 atgaaatgat taaccctatc acaggcacta cttacgctat gtttgaacct gcccttgatt
     5461 acgttgttgc taaaattccg cgttttccgt ttgataaatt tgaacatggt gaacgccaac
     5521 tgggaactca aatgaaagca acaggtgaag tcatggctat tggccgtaat ttggaagagt
     5581 ccttactaaa agcctgtcgt tctttagaaa ttggtgtttg ccataatgag atgacaagtt
     5641 taagtaacat tagtgatgaa gagttagtga ctaaagtgat taaagctcaa gatgatcgac
     5701 ttttttactt gtcagaagca atacgacgag gttatagtat cgaagaactt gagagcttga
     5761 ccaagattga tttatttttc ttggataaat tacttcatat tgttgaaata gagcaagaat
     5821 tacaaatgca tgttgaccat ttggaaagcc tcaaaaaagc aaagcgttat ggattttcag
     5881 atcaaaaaat tgcagaaatt tggcaaaagg atgaaagtga tatcagagcg atgagacatt
     5941 ctcatagcct gtatcctgtc tataaaatgg tagatacttg tgcagctgaa tttgatgcta
     6001 aaacccctta tttttattca acatatgagt tggaaaatga atctgttcag tcgaataaag
     6061 aatcaatttt agttttaggt tcaggcccta ttcgtattgg tcaaggggtt gaatttgact
     6121 acgcaacggt tcattctgtt aaagccatcc aaaaagctgg ctatgaagcc attatcatga
     6181 attcaaatcc ggagactgta tctacagatt tttcggtatc agataaatta tattttgaac
     6241 cgttaacctt tgaagacgtc atgaatgtga tagatttaga gcagcctaag ggagtaatag
     6301 ttcagtttgg aggacaaact gctattaact tagcacaagc actttctgag gcgggtgtta
     6361 caatattagg aacacaagta gaggatttgg atagggctga agacagagat ttatttgaaa
     6421 aggcgttgaa agagcttgga atcccacaac cacaaggtca aacggcaact aatgaagaag
     6481 aagctttaga ggcagctaaa aaaattggtt ttccagtctt agttagacct tcttacgtac
     6541 ttggtggccg ggctatggaa attgttgaaa acaaagaaga tcttagagaa tatataagaa
     6601 cagcggttaa agcaagtcct gaacatccta tcttagtgga ctcttatatt ttcggtaagg
     6661 agtgtgaagt ggatgccatt tcagatggaa aatcagtctt aattcctggt attatggagc
     6721 acatcgaaag agcaggtgtt cattcaggag attcaatggc agtttatccg ccacagcaat
     6781 tatctaagca aattcaagaa acaatagctg agtatactaa acgtttagcc attgggttaa
     6841 attgtattgg tatgatgaat gttcaatttg ttattaaaaa tgaacaagtt tatgttattg
     6901 aagtgaatcc acgcgctagt cgtaccgtac ctttcttatc aaaagtaaca ggtattccga
     6961 tggctcagat tgctactaag ttgattttag gtcaaacatt aaaggatcta ggatatgaag
     7021 atggtcttta tccccaaagt ccactggtgc atatcaaagc gcctgtgttt tcatttacaa
     7081 agttggcaca ggttgatagt cttttaggtc ctgaaatgaa atcaactgga gaagtaatgg
     7141 gttcggatac tagtcttgaa aaagcacttt ataaagcgtt tgaagccaat aattctcatt
     7201 tatcagaatt tggtcaaatt gtctttacta tagcagatga tagtaaggca gaagctctaa
     7261 gtctagcaag acgatttaag gcgattggct atcaaattat ggctactcaa ggtacagcag
     7321 cttactttgc tgagcaaggc ttaagcgcgt gtttagttgg aaaaattggt gatgctgcca
     7381 atgacatccc gacactcgtg cgacatggtc acgttcaggc aattgttaat acagttggaa
     7441 ttaaacgcac agctgataaa gacggacaga tgattagaag ttcagctatt gaacaaggag
     7501 ttcctttatt tacagcttta gataccgcaa aagctatgtt aacggtttta gaaagcagat
     7561 gctttaacat cgaagcgata taaaaattaa aaaaatcatt tttaagaaaa cttaaaaatg
     7621 atttttttag attataatga caaaagtttc agtaagctat taatttgtca tagcatataa
     7681 gtcattatct tgtggcttgt tttcgactaa gggctaagaa tttcttgaca acaatataaa
     7741 aaggtcatat acttgtctta tacaaatagt acaaaagagg aggatagaaa tgtctaaaag
     7801 aggaaaaatt aaaataacaa cgaaaacaaa gcttattaca gctagtgtta taacgctagt
     7861 attaattata actggaatag tcttgtggaa acaacaacga aatacgctaa cagctgatat
     7921 cgctaaagaa ccttactcta ctgttagtgt aactgaaggg agtattgctt cttcgacttt
     7981 actatcaggt actgtaaagg ctttatcaga ggaatatatt tattttgatg ctaataaagg
     8041 aaatgatgca actgttacag ttaaagtagg tgatcaggta acgcagggcc agcaattagt
     8101 tcaatataat acaacaacag ctcagtcagc ttatgatact gctgttagga gtcttaacaa
     8161 gattggccga caaattaatc atcttaaaac atacggagtt cctgctgtta gtacagaaac
     8221 taatagagat gaagctaccg gtgaagagac gacaacaaca gttcaaccat cagctcagca
     8281 aaatgctaat tataaacagc agctgcaaga tttaaatgat gcttatgcag atgcacaagc
     8341 agaagtaaat aaagcgcaga tagcgttaaa tgatacagta gttatcagta gtgtctctgg
     8401 aactgttgtg gaagtaaata atgatattga tccttcttca aagaacagtc aaacacttgt
     8461 tcacgtagca accgaaggac agcttcaggt gaaaggaaca ttgacagagt atgatttagc
     8521 aaacgttaag gttggtcaat ctgtaaaaat taagtctaaa gtttattcta atcaagaatg
     8581 gactggaaaa atatcatatg tttcaaacta tccaactgag tctaatgcag gttcaacaac
     8641 gccagcaggt agcactggag cgggaagttc tacaggagct acctatgatt acaagattga
     8701 tattataagt cctctcaacc agcttaaaca aggcttcact gtttctgttg aggttgttaa
     8761 tgaagcaaaa caggccttag ttcctttaac ggctgttatt aagaaagata aaaaacacta
     8821 tgtttggact tatgatgatg ctactggcaa agccaaaaaa gtagaggtga cacttggaaa
     8881 cgcagatgca caacaacaag aaattcataa aggagtagct gttggtgaca ttgttattgc
     8941 caatccagat aaaaatatca aaccggataa aaaactagaa ggggttattt caataggtac
     9001 caacacaaaa ccggaaaaag attctcaatc aaagaataaa aaatcagggg tggataaata
     9061 gtgtcgcatg aaaaaaaaca attaatgcaa ttatcaaata ttgtgaagag ctatcaaaat
     9121 ggggatcaag ttcttaaagt tttgaaaggt attaatttaa cagtatatga gggtgaattt
     9181 ttagctatta tgggtccgtc tggttcggga aaatcaacac taatgaatat tattggttta
     9241 ttagatcgtc caacatccgg agattacaca ttacataata ctaaaataga aatccttaat
     9301 gatcgtgaat tagcaaaagt acgaaatgat gaaatcggct ttgtctttca acaattcttt
     9361 ctgttagcta aattaactgc attacaaaat gttgaattgc ctcttattta tgctggtgta
     9421 aacgtctcaa aaagacgtga acaggctaag caatttcttg aaaaagtagg acttggacga
     9481 cgtatcaaac atctaccgtc agaactgtca ggaggtcaaa agcaaagggt ggctatcgca
     9541 cgagctttag taaatgaccc atctattatt ttagcggatg aaccaacagg tgcactagat
     9601 actaaaacag gtcagcaaat tatggaactc ttgacagagt taaacaaaga aggtaaaaca
     9661 attattatgg ttactcatga accagaaatt gctgattttg caactcggaa aattattatt
     9721 cgtgatggtg atatcacaac ggatactaca gctagtgttg ttattgacta ggaggaaaaa
     9781 taatggaaaa ttggaaattc gctcttagct caatttgggg gcataagatg cgctcaatcc
     9841 tgacaatgtt gggaattatc atcggtgtag cagcagttgt gattattatg gggttgggaa
     9901 atgctatgaa aaatagtgta acaagcacat tttctagcaa gcaaaaagat attcaactct
     9961 attttcaaga aaaaggagaa gaagaagacc tgtatgccgg attgcacacg catgaaaata
    10021 atcacgaagt gaagccagag tggttagaac aaattgttaa agatatcgat ggtattgatt
    10081 cttattactt taccaattct gctacttcta ctatttcgta tgaaaaaaag aaagtagaca
    10141 atgcttcgat cataggggta agtaaagatt attttaatat aaaaaactat gatatcgtag
    10201 ctggtcgtac actaacagat aatgattatt ctaatttttc gcgtatcatt cttttagata
    10261 cagtattagc cgatgaccta tttggcaaag gtaattataa gtcagcttta aataaagtgg
    10321 taagtttatc tgataaagat tatttagtta ttggtgttta taaaactgat cagacgccag
    10381 tttcttttga tggattatca ggcggcgctg tcatggcgaa tactcaggta gcttcagagt
    10441 ttggcaccaa agaaatagga tctatctaca ttcatgtgaa cgatattcaa aacagtatga
    10501 acttaggaaa tcaagcagct gatatgctaa ccaacatatc gcatattaaa gatggacagt
    10561 acgctgtccc tgataatagc aaaatcgttg aagaaatcaa tagtcagttc agtatcatga
    10621 caacagtcat aggttcaatt gcagcgatct ctcttttagt gggaggaatt ggtgttatga
    10681 atattatgtt ggtatctgtc acagagcgaa ctagagaaat tggtttacgt aaagcacttg
    10741 gtgcaacacg cctgaaaatt ttatcacaat ttttgattga atccgttgtt ctaacagttc
    10801 ttggaggctt gataggatta ttattagctc aattaagtgt aggggcttta ggaaatgcga
    10861 tgacattaaa aggagcttgt atttctcttg atgtggcctt aatagcagtt ttattttctg
    10921 cctcaatagg tgtctttttt ggaatgttgc cagctaataa agctagtaag ttagatccaa
    10981 ttgaggcatt acgttatgaa tagaatagtt cgtatcaatt aatctataga cgctgactag
    11041 tttaacgtct gattatacct agtttttgta ttagcacagt agttatatca ttgaagtgtt
    11101 agtgcatttt ttgaggtgat aatatctagc aaagctatca ttggtatgat gatgtggata
    11161 gcgtataagt gatacatctc ttatttctag ctgaacttcg gttcggctag gaagttgtca
    11221 ggcaatgagt tgtttaaaat aaaggagatt agttcaatga catttttatc tgatttgata
    11281 tcattaatga caaaaatcag attatcttgg gtaataaagg cgggtatttt tcaattatta
    11341 tttgtaacga ttgctaatat tgtcttatca gaatttttct attttatatt agacgttact
    11401 ggtcaatatc atttagataa agacaatgtt gtgacttttt taaaaaatcc tatagcactt
    11461 gctttattag gtgcctattt atttttatta gctgctttta ttcaccttga gttttttgct
    11521 ctatatcgaa ttattgcgga tcaagaaatt agtttctatc tttttagaaa acagttttct
    11581 tattacctaa gggggctttg gaaaacattt tctggttacc aattattact ttttttgctt
    11641 tatatcctat tgactattcc agtcttacat attggtttat cttctgtgat tactcaaaag
    11701 ctttatcttc cagaatttat tgttggggaa ttatcaaaga taactagcac aaagtacttg
    11761 ctttatggca gtcttattct tgtgttttac cttaacctaa gattagtata ttttttacca
    11821 ttgatagcaa tcaaccatcg tacggttgct caagcatgga gagagagttg gcaaaagact
    11881 aaaaagaaac atgtattgtt atggatgaaa ctttttgcaa tcaatggtct tacgattgta
    11941 gtcttatcgc tagctatttc catgattctt atttttgttg atatgtttaa tcctaagggg
    12001 aataatatta ttgttcagct gggagctttg acctttacat gggaactcat tttttttact
    12061 actatttttt ttaaactctg ttcagcaatg attttaaaag aggcaattga accacaaaag
    12121 caatatgatg agccaagaag aagtaataag gcatatgttg taatctttat cgtggttaca
    12181 gtaggttttg cttatcaatc tcttgaacgt ttaacttttt ttgacacatc tcactctaag
    12241 acagttatcg cgcatagagg acttgtatca gcaggtgtag aaaattctct ggaagccctt
    12301 gaaggtgcta agaaagcagg aagtgattat gtagaactgg atctaatctt gactaaggat
    12361 aatcactttg tggtgtctca tgataatcga ttgaagcgtt tagctggagt aaataagacg
    12421 attcgcaact taaccttaaa agaagttgaa catctaacga gtcatcaagg acatttttca
    12481 gggcgttttg tttcttttga caccttttat caaaaggcta agaagttgaa tatgccatta
    12541 cttattgaac tcaagccaat tggtacagaa cctggaaatt atgtcgattt gtttttagaa
    12601 acttatcatc gacttggtat aagcaaagat aataaagtca tgtctttaga tttagaagta
    12661 atagaagcta tcaagaaaaa aaatccatca attacgactg gttatatcat accaattcaa
    12721 tttggatttt ttggagatga atttgttgat ttctatgtca ttgaagactt ttcttatcgg
    12781 tcttatttgt cgtcccaagc tttttggaat aataaagaaa tttacgtttg gactattaat
    12841 gatcccaagc gcatagagca ttatctccta aagcctattc agggaattat tacagaccaa
    12901 ccagctttaa ctaatcaatt gattaaagac ttaaaacaag ataattctta ttttagtcga
    12961 ttagtcagaa ttattagtag tctttattaa aggtttaagg aaagtgtcaa gaaaaaaact
    13021 tgacactttc tttaaactga gttatactgt ttaacatagg aatttagcgt agctgtattt
    13081 cttatacatt actaaaagaa aagagactat ttaaaaatgg cagtaaaaat ccgtttaact
    13141 cgtatgggtt ctaagaaaaa acctttctac cgtattaatg ttgcagattc acgtgcacca
    13201 cgtgatggtc gttttatcga aacagttgga acatacaacc cattagtggc tgaaaatcaa
    13261 attactatta aagaggatcg tgttcttgag tggttatcta aaggagcgca gccttctgat
    13321 accgttcgta acatcttgtc taaagctggt gttatggcta agttccacga ccaaaaattc
    13381 tctaaataat aacagcctat ggataccatt gaaaatctta ttatcgctat tgtgaaacct
    13441 ttgatttcac aaccagataa tcttaccatt aaaattgaag atactcctga ctttttagag
    13501 tatcatcttg acttggatgc tcaagacatc ggtcgtgtta tcggcaaaaa aggtcgaact
    13561 attactgcga taagatcgat tgtctactcg gttccaacac taggaaaaaa agttcgctta
    13621 gttattgatg agaaataatc actaacttga gatggattga aaagcttgtt gacttaaagt
    13681 caacaagctt tttgaatagc aaaaatctta atatttctga aatgaaaaga ttagattttt
    13741 ctgtctttaa ctaaaaagaa gttaaagaat ggcttagctg attgccttta taagagatta
    13801 tactggtttt tgatagctgc tgtcatgtaa aatagctaca attcatctta cgagatagtc
    13861 tttattttcc aacctgctgt ttgttgtatg tttatagttt cctaaaaaat gctctctcag
    13921 ttttttgggg ggcattccta aaattaagta tacttaattt taggaatgtt tatattcttt
    13981 acattctgat gaaaatacaa attatcctaa catgatgtat tgaaagggga aatagtttat
    14041 gttagtatac tgattaagtg aagctgtaat gaggcttata cgatcaaaaa agttagagta
    14101 actttataaa acagtggtgt tgaagcaagt ttagcttctt ctcagaaata gattatctat
    14161 aaaaaatccc aaaagtagtt tgtttccagt taatgaactt cttttgggaa ggcttttttg
    14221 ctgatcgcca cttcacttgt atatcgggaa cattcacgct aagatgtata agttgaatcg
    14281 tttgtctatg gcttgatgaa aattaatcaa aagataatgt tcaactctat aattagtaca
    14341 agcaaaatga gatagcttat tcattagtaa gcataagata taacaagaga aattacctta
    14401 aaacaggaag tactagagta tttaaaataa gtgatagact tggatattat taggtcgact
    14461 agtgttcttt tcaataattt aatatcgtta ttattagtat cagccaatca aatgtggata
    14521 agttggcttt tagaaaggtt ttaccacaat gaagaaacat cttaaaacag ttgccttgac
    14581 cctcactaca gtatcggtag tcacccacaa tcaggaagtt tttagtttag tcaaagagcc
    14641 aattcttaaa caaactcaag cttcttcatc gatttctggc gctgactacg cagaaagtag
    14701 cggtaaaagc aagttaaaga ttaatgaaac ttctggccct gttgatgata cagtcactga
    14761 cttattttcg gataaacgta ctactcctga aaaaataaaa gataatcttg ctaaaggtcc
    14821 gagagaacaa gagttaaagg cagtaacaga gaatacagaa tcagaaaagc agatcacttc
    14881 tggatctcaa ctagaacaat caaaagagtc tctttcttta aataaaacag tgccatcaac
    14941 gtctaattgg gagatttgtg attttattac taaggggaat acccttgttg gtctttcaaa
    15001 atcaggtgtt gaaaagttat ctcaaactga tcatctcgta ttgcctagtc aagcagcaga
    15061 tggaactcaa ttgatacaag tagctagttt tgcttttact ccagataaaa agacggcaat
    15121 tgcagaatat accagtaggg ctggagaaaa tggggaaata agccaactag atgtggatgg
    15181 aaaagaaatt attaacgaag gtgaggtttt taattcttat ctactaaaga aggtaacaat
    15241 cccaactggt tataaacata ttggtcaaga tgcttttgtg gacaataaga atattgctga
    15301 ggttaatctt cctgaaagcc tcgagactat ttctgactat gcttttgctc acctagcttt
    15361 gaaacagatc gatttgccag ataatttaaa agcgattgga gaattagctt tttttgataa
    15421 tcaaattaca ggtaaacttt ctttgccacg tcagttaatg cgattagcag aacgtgcttt
    15481 taaatcaaac catatcaaaa caattgagtt tagaggaaat agtctaaaag tgatagggga
    15541 agctagtttt caagataatg atctgagtca actaatgcta cctgacggtc ttgaaaaaat
    15601 agaatcagaa gcttttacag gaaatccagg agatgatcac tacaataacc gtgttgtttt
    15661 gtggacaaaa tctggaaaaa atccttctgg tcttgctact gaaaatacct atgttaatcc
    15721 tgataagtca ctatggcagg aaagtcctga gattgattat actaaatggt tagaggaaga
    15781 ttttacctat caaaaaaata gtgttacagg tttttcaaat aaaggcttac aaaaagtaaa
    15841 acgtaataaa aacttagaaa ttccaaaaca gcacaatggt gttactatta ctgaaattgg
    15901 tgataatgct tttcgcaatg ttgattttca aaataaaact ttacgtaaat atgatttgga
    15961 agaagtaaag cttccctcaa ctattcggaa aataggtgct tttgcttttc aatctaataa
    16021 cttgaaatct tttgaagcaa gtgacgattt agaagagatt aaagagggag cctttatgaa
    16081 taatcgtatt gaaaccttgg aattaaaaga taaattagtt actattggtg atgcggcttt
    16141 ccatattaat catatttatg ccattgttct tccagaatct gtacaagaaa tagggcgttc
    16201 agcatttcgg caaaatggtg caaataatct tatttttatg ggaagtaagg ttaagacctt
    16261 aggtgagatg gcatttttat caaatagact tgaacatctg gatctttctg agcaaaaaca
    16321 gttaacagag attcctgttc aagccttttc agacaatgcc ttgaaagaag tattattacc
    16381 agcatcactg aaaacgattc gagaagaagc cttcaaaaag aatcatttaa aacaactgga
    16441 agtggcatct gccttgtccc atattgcttt taatgcttta gatgataatg atggtgatga
    16501 acaatttgat aataaagtgg ttgttaaaac gcatcataat tcctacgcac tagcagatgg
    16561 tgagcatttt atcgttgatc cagataagtt atcttctaca atagtagacc ttgaaaagat
    16621 tttaaaacta atcgaaggtt tagattattc tacattacgt cagactactc aaactcagtt
    16681 tagagacatg actactgcag gtaaagcgtt gttgtcaaaa tctaacctcc gacaaggaga
    16741 aaaacaaaaa ttccttcaag aagcacaatt tttccttggc cgcgttgatt tggataaagc
    16801 catagctaaa gctgagaagg ctttagtgac caagaaggca acaaagaatg gtcagttgct
    16861 tgaaagaagt attaacaaag cggtattagc ttataataat agcgctatta aaaaagctaa
    16921 tgttaagcgc ttggaaaaag agttagactt gctaacagga ttagttgagg gaaaaggacc
    16981 attagcgcaa gctacaatgg tacaaggagt ttatttatta aagacgcctt tgccattgcc
    17041 agaatattat atcggattga acgtttattt tgacaagtct ggaaaattga tttatgcact
    17101 tgatatgagt gatactattg gcgagggaca aaaagacgct tatggtaatc ctatattaaa
    17161 tgttgacgag gataatgaag gttatcatgc cttggcagtt gccactttag ctgattatga
    17221 ggggctcgac atcaaaacaa ttttaaatag taagcttagt caattaacat ctattcgtca
    17281 ggtaccgact gcagcctatc atagagccgg tattttccaa gctatccaaa atgcagcggc
    17341 agaagcagag cagttattgc ctaaaccagg tacgcactct gagaagtcaa gctcaagtga
    17401 atctgctaac tctaaagata gaggattgca atcaaaccca aaaacgaata gaggacgaca
    17461 ctctgcaata ttgcctagga cagggtcaaa aggcagcttt gtctatggaa tcttaggtta
    17521 cactagcgtt gctttactgt cactaataac tgctataaaa aagaaaaaat attaaattga
    17581 tttaaggaga aaaaatgata acacaagaaa tgaaagatct tattaataac caattagcaa
    17641 tggttgcgac ggttgatgcc aaaggtcaac ccaatattgg tccaaaacgt tctatgcgtc
    17701 tctgggatga taaaacattt atttataatg aaaatacaga tggtcaaact cgtattaaca
    17761 ttgaagataa tgggaaaatt gaaattgcct ttgttgatcg tgagcgcctt ttaggttaca
    17821 ggtttgtagg aactgctgaa attcaaacag aaggtgctta ttacgaagca gcgaaaaaat
    17881 gggcacaagg acgcatgggg gtaccaaaag cagttggtat tattcatgtc gagcgtattt
    17941 ttaatttaca atctggtgct aatgcaggta aagaaataaa cagtgaaagt aactaaaatt
    18001 aactgtaaca gtatttagga cccttatttt aaacgctaaa aaacaagcat actctttttt
    18061 acagcatagt gactatgttg taaaaagggg tatgcttatt aggtgctctt aatatttata
    18121 gataactgca cctaataagt tttcaataga cttatagcac attaattgac ttcaattagt
    18181 tgacttcaat actagaaaga gaagaacagt gatgttggtg ttcgtttaaa gaagtatcga
    18241 tttccacagt gactgagttt atattgtacc tttgacaaat cagtctaata gattttttgc
    18301 aatgtttttc agtggtagat tctctcaagc agcaatgtat agttgctcta tgatcaatac
    18361 catccatcga ccaaacatta agctgattaa cagacactat atgaggaagt tggctgagtt
    18421 catggtgcaa agtgcaatag tctatagaat caggaacacc atctaaaaaa atgttagcag
    18481 ttgctactaa ctttggaaga gctttagata atataaaaga agcaatggca attgataata
    18541 aaggatcaag aatgtaccaa ggtttccatt ttaagatcag tgacagtatg ataatggcta
    18601 accacccaag gatatcttct aaaaagtgaa ggcttaatat ttcttcattt tttgtctggt
    18661 tagagtgaat gatgaagcta gcaaatccat tgattataat tgcaaaaata gctaaaacga
    18721 acataccgtc ataattaaca atagtaggat gccataattt tggtatcgtt tcaatcatta
    18781 ctaataatga cccgctaata agtattagat ttgtcgttag cgctcctaaa aggctaaatc
    18841 gcttatagcc tagtgaaaaa tttggactct cttttttaac agcctttctt tctaagatag
    18901 ctgagatacc aatagcaatg gcatctccaa aatcgtggac agcatctgct aaaatagcac
    18961 ccgaaaagaa taatgtccca aaaataaatt caatgaggga aaaactaaga tttaatataa
    19021 aaataatggt gactttttta cttgctggca taattttctc cttttgttat actggta
//
LOCUS       DAUGQX010000037        18607 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUGQX010000037 DAUGQX010000000
VERSION     DAUGQX010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18607
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.037"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..590)
                     /gene="smeZ"
                     /locus_tag="VIA51_001319"
     CDS             complement(<1..590)
                     /gene="smeZ"
                     /locus_tag="VIA51_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal mitogenic exotoxin SmeZ"
                     /protein_id="HEQ8683262.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKDGDKIAMFSVPFDWNYL
                     SEGKVIAYTYGGMTPYQEEPMSKNIPVNLWINRKQIPVPYNQISTNKTTVTAQEIDLK
                     VRKFLISQHQLYSSGSSYKSGKLVFHTNDNSDKYSL"
     gene            complement(839..1345)
                     /locus_tag="VIA51_001320"
     CDS             complement(839..1345)
                     /locus_tag="VIA51_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEQ8683263.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERS
                     DHDMIADLSTCLLKQDLIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLN
                     YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVVQKYSHKTIVLTNQKQL
                     SHYMNTIN"
     gene            complement(1400..1840)
                     /locus_tag="VIA51_001321"
     CDS             complement(1400..1840)
                     /locus_tag="VIA51_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8683264.1"
                     /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KEDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLAFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            complement(1979..2051)
                     /locus_tag="VIA51_001322"
     tRNA            complement(1979..2051)
                     /locus_tag="VIA51_001322"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2016..2018),aa:Lys,seq:ctt)
     gene            complement(2052..2248)
                     /gene="ssrS"
                     /locus_tag="VIA51_001323"
     ncRNA           complement(2052..2248)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VIA51_001323"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(2337..3605)
                     /locus_tag="VIA51_001324"
     CDS             complement(2337..3605)
                     /locus_tag="VIA51_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEQ8683265.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDGSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            complement(3638..4204)
                     /locus_tag="VIA51_001325"
     CDS             complement(3638..4204)
                     /locus_tag="VIA51_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEQ8683266.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            complement(4237..5994)
                     /gene="pabB"
                     /locus_tag="VIA51_001326"
     CDS             complement(4237..5994)
                     /gene="pabB"
                     /locus_tag="VIA51_001326"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEQ8683267.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDL
                     IDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFL
                     EQHLNRLKEAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            6194..6664
                     /locus_tag="VIA51_001327"
     CDS             6194..6664
                     /locus_tag="VIA51_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEQ8683268.1"
                     /translation="MATYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEAASYPYPRY"
     gene            6735..7688
                     /locus_tag="VIA51_001328"
     CDS             6735..7688
                     /locus_tag="VIA51_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEQ8683269.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADIIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            7688..8437
                     /locus_tag="VIA51_001329"
     CDS             7688..8437
                     /locus_tag="VIA51_001329"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEQ8683270.1"
                     /translation="MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLADEAEVVLVFDDG
                     VKYLAKVTNSMAHELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAASAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            8795..10981
                     /locus_tag="VIA51_001330"
     CDS             8795..10981
                     /locus_tag="VIA51_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8683271.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDACMTRLRVTVKDP
                     AKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLT
                     SKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL"
     gene            11064..11882
                     /locus_tag="VIA51_001331"
     CDS             11064..11882
                     /locus_tag="VIA51_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEQ8683272.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMDDETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKGADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLGWR"
     gene            complement(12276..12758)
                     /gene="nrdI"
                     /locus_tag="VIA51_001332"
     CDS             complement(12276..12758)
                     /gene="nrdI"
                     /locus_tag="VIA51_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8683273.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGDVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            13140..14186
                     /gene="slc1"
                     /locus_tag="VIA51_001333"
                     /gene_synonym="slcA"
     CDS             13140..14186
                     /gene="slc1"
                     /locus_tag="VIA51_001333"
                     /gene_synonym="slcA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin Scl1"
                     /protein_id="HEQ8683274.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEVSSTTM
                     TSSQRESKIKEIEESLKKYPEVSNEKFWERKWYGTYFKEEDFQKELKDFTEKRLKEIL
                     DLIGKSGIKGDRGETGPAGPAGPQGKTGERGAQGPKGDRGEQGIQGKAGEKGERGEKG
                     DKGETGERGEKGEAGIQGPQGEAGKDGAPGKDGAPGEKGEKGDRGETGAQGPVGPQGE
                     KGETGAQGPAGPQGEAGKPGEQGPAGPQGEAGQPGEKAPEKSPEGEAGQPGEKAPEKS
                     KEVTPAAEKPADKEANQTPERRNGNMAKTPVANNHRRLPATGEQANPFFTAAAVAVMT
                     TAGVLAVTKRKENN"
     gene            14438..16657
                     /locus_tag="VIA51_001334"
     CDS             14438..16657
                     /locus_tag="VIA51_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEQ8683275.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGHDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            16672..17115
                     /locus_tag="VIA51_001335"
     CDS             16672..17115
                     /locus_tag="VIA51_001335"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEQ8683276.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     SQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(17213..18535)
                     /gene="ska"
                     /locus_tag="VIA51_001336"
     CDS             complement(17213..18535)
                     /gene="ska"
                     /locus_tag="VIA51_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEQ8683277.1"
                     /translation="MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQL
                     VVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEK
                     ADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQE
                     FLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGD
                     TITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQ
                     AYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVT
                     VYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK"
BASE COUNT         5445 a         3600 c         4264 g         5298 t
ORIGIN      
        1 tcgagagaat atttatctga attatcattt gtatgaaaaa ctaatttacc acttttgtag
       61 ctagaaccag aagaatataa ttgatgttgt gatattaaaa attttctaac ctttagatca
      121 atttcttgag ctgtaactgt tgttttgtta gttgatattt gattataggg gacaggaatc
      181 tgctttctat taatccataa attaacaggg atatttttag acattggttc ttcttgataa
      241 ggcgtcattc caccataggt atatgctatg acttttcctt ctgacaagta gttccaatca
      301 aatgggacgg agaacatagc tattttatct ccatctttaa aatcattggc tgcatattca
      361 tccatttcgg agttaataaa aaaatctcta gcatctctaa catcaagttt cttagtcact
      421 aagttatgac tggttttaaa atcaattact gtatctgaat attcatatac aatcgtacta
      481 tagatattcc ttagaaggga attattatct acttctaatc caaacacagg acgagaaatt
      541 attgcaatga atattgaagt aaaagaaaaa ataagttttg tttttttcat aaatagcctc
      601 ttttcaggag ttattatttt attatgtttt aatataacac tttcaaaaga aataatcatt
      661 aacaattttg tagatatact tgctgactat cgaatgaaaa ttgagacatg atactaaaag
      721 tggattgacg cttttaatta agccgattag ttatgaaaca agcaaaaaag cctttaaaca
      781 aaggctttca gtctgaatag cccggattac ccgtggttat tttagttttg cactctaatt
      841 agttgatcgt attcatataa tgacttagct gcttttgatt tgttaagaca atggttttat
      901 gagagtattt ttggacaacg gattggtatt tttttaattg gtttcttgaa cgtccatcta
      961 gtagaatcca tttcacaaac gcaacgtcaa atttttcctg acagttgtca gccatatcag
     1021 gacgcgtttt tcccctatag tttaaataac gcttaaatgc tcgatagaca caatgaaacc
     1081 gactgaaatt aacatagata atgtaatcag cttcactcat gcgctcttca tagagacaat
     1141 tggcataatt cccctcaata atcaaatctt gtttgagcag gcatgttgat aaatcagcta
     1201 tcatgtcatg atctgaccgt tcttgccagt tcgatgagaa gtgtagttgg tctaaatgga
     1261 atacctcaca atggtaatgt tggcctaaaa atcgtgctaa ggttgacttg ccagagccac
     1321 tatgtccaat gatggcaatt ttcaatggat acctcctaaa aatgacgtat gaaatgacta
     1381 taaagggtag gaaatgtgtt tagattagtt tcttgatgag atgcgtgtca tcatagaatt
     1441 gataaccatg tttaggataa aaccgataag attcaaacca ttgttcttta ggttgaccta
     1501 agtggatacg aacatgactc ttgccgattt tccttagata atcttctgca aacgccagaa
     1561 gttgactgcc aatgccttga tgttttaagc ttggtttgat gaagagacgg tgcaagaaga
     1621 cctcatttgt tttgggaata gaagaataag cgattgagcc aataacacga ctttcttcat
     1681 tgaccgctag ccaaaaacaa tcctcttttt ccaaataact tgtttcaatt gtcaaaagat
     1741 ccgggttaat gctgggaatt ctccttaagg cattttttgc ttccaagacc ataaaaatga
     1801 ggtcatctct gtaatttcct ttgtactcaa ttattttcat aacagtctcc accttaatct
     1861 taagcgcttt aattggtatc ataccataaa aaattactgc ggggataaat gatggaacaa
     1921 atcctcttct gacaagcaaa aaaagccttt aaacaaaggt tttttcatgt atagtttata
     1981 ccccctacag ggctcgaacc tgtgacccat agattaagag tctactgctc taccaactga
     2041 gctaaggagg caagaatgct gtattggcac cggtgatcca cgtttttgta ttgagcccgc
     2101 gcagtataag caggtgggta acgcgctctt tcttggaagt tgcgtccgcg tgaaacggct
     2161 tgcagactag aaagagtctt tgtttcccga aaatacaaag aaatagtcgg tcaacactta
     2221 gatgtggatt cgtatgccac agcaatgttt ctgtactttt ataataccac tttttaaaat
     2281 tttttcaagc aaaattatcg atttttgaaa tcggttgcga tttttaaaac tagcagtcag
     2341 tctgagagct tatcaatacg ctctttattt gaaccaagtg cgcgttcgta tttaccggtt
     2401 tcattggctt caaaataatg atgtcctact aatttatctg gtaggtattg ttgtttgacc
     2461 catttttcag ggtaggcgtg tgggtagagg taatctttgg cattgcctag gtccttgctg
     2521 ccagcataat gcccgtctct aagatgtctt ggaatgggga ggttgcctga tgttctcaaa
     2581 tcagctaaag ctgcatccat agctaaataa gctgaattgg atttaggtga tagagccaaa
     2641 tcaatgacca cgttagcgat aagaatacga gcttctggaa aaccaatgcg ttgggcggca
     2701 tctagtgcgg tgacggtatg aacttgggcg tcagggttgg ctaagccaat atcttcgtaa
     2761 gcaataatgg tcaatcgtct tgctaaacta ggcaagtctc cagcttctac taaacgagcg
     2821 gcatagtgca ggctagcatt gacatcagaa cctctaatgg atttttgtaa ggcagataaa
     2881 acatcataat gcccgtcccc gtttttatcc atggtaatat aactacgctg cagactattt
     2941 tccattgtct ctagactaat atgacgacta ccatcttcat taggagaagt agacatgact
     3001 gctagatcca aggaattata agcagatcgt aggtctccat ttgtggcggt aacaatgaaa
     3061 tctagcgcct catcatcaat tgtcactaaa aaaggaaatc cccgttcttt gtcggaaatt
     3121 gctagctgaa tggctgtttt aatatcctcg ttagaaagtg gttccaattc aaaaatttgg
     3181 accctgcttc tgatagcggg tgtcactgaa aagaaggggt tctcagtggt tgcgccaatc
     3241 atgataatgg tgccattctc aagtaaaggt aaaagaaaat cttgttttgt cttgtcaagg
     3301 cgatgaatct cgtctagtaa taataccaag ccaccagaaa atttagcttc ttccgcaatt
     3361 tcttggagac gttttttgct gtcaatggtg gcattaaagg tccgaaaggc atatctagta
     3421 gtaccagcaa tagcagaagc aatggaagtt ttaccgattc ctggagggcc atagaggatc
     3481 atggacgata gtctatttgc ttccaccatg cgacggatga ttttgccttc gccaacaagg
     3541 tgtttttgtc cgatgacctc tgaaatggtt ttggggcgca ttctgagcgc taaatgatca
     3601 ggcatgtaac tgtcctcctt tcttttgggg gatgagatta acggggaatg gctgcgatga
     3661 agttggcaat catggtcatg ccatcaggag ttccgatgct ttctgggtga aattgtagcc
     3721 caaaaagtgg cagggtgtgg tgttcaaatg ccatgatttc ttgatcgtca cagtctctag
     3781 cggttacgct aaaacctttt ggtaactgat ccacaacgat ggaatggtag cgcatgacgg
     3841 tgatctcttg tggcagggag cgaaaaagac tagcagggcc ttgcgtttca atggtgcttt
     3901 gtctcccatg catgacgcgt ttggccaagc gtaaggttcc ccctaaagtt tcagcgatag
     3961 cttggtgtcc cagacacact cctaagatag gttttgtttg gtaaaagtct tgaatgagtt
     4021 ttggcatttg gttggcttcc ttgggccaac caggaccagg tgagaggact agagcgttag
     4081 cttttttggc catgtcatat aagtttgggt cttggttata caagacaatc gtctcgtcaa
     4141 attcacttaa atattgggcg aggttgtagg taaatgaatc gtaattatca attaagagta
     4201 tcataggttc cttaataaca aaagatgagt ggcagtttag gcttgactct tagctaagag
     4261 ggcatcaagg tgagtaagct caaggttgag aggataaagg ccacggacag catttcctcc
     4321 aaaaatagcg ctagcctctt ttaaatcagc tagtgtcacc tctttttcct gagcttgacc
     4381 agtagctagc agttcttggc gaaaaagtcc tggtaaaatc cccacagcca ctggtggtgt
     4441 gtagagggtc tgacccagct gaacaaagag attgccaatg gacgtttcca ataattgccc
     4501 cgcttggtta tagaatagct gttcataaga tttttgctca atatgaggcc ggtagctggt
     4561 cttaaagtag gtaaaaggcg aagctgtcac gtcctttttc tgtaaagaga gttgagctgt
     4621 cagaaaatcg gctgacaaag gttccaaggg ttgatcagag aggctaatct ttccatcttt
     4681 ggataaacga atcatcaaac ggtaggcagc attattctta ttttccaaat aggttgacag
     4741 ttgtttctgc aaagcttttt cattataagg gtaagcaaaa taagtggctg cttctttaag
     4801 gcgattgagg tgttgctcaa ggaaggctat ttttttgtgt tccaccttgg cggttgtttt
     4861 gaggtcaaag atttgtttgt gccgatagag aaaagctgtt ttttgatgga cttcctcgta
     4921 ttcgtcttcc cacttgcttt gccaagtgat gccgcctccg acaccataag tagcttgatt
     4981 atgactgagc tggatggttc taatgggaac attgaagaaa cggcgaccat caggtaggca
     5041 aatgccaata cttccacaat aaatccccct tggttttggc tccagagatg tgataattgc
     5101 catggtggag acttttggtg cccctgtgat agagccacaa ggaaagagag ctttgagaat
     5161 gtctatcagg tcacagtccg ctttgaggtc accaacaata gttgaggtca tttgccagac
     5221 ggtagagtat cgctcgacct cacagagcct atcaacacga acactgcctg tttggcaaat
     5281 tttccccatg tcattgcgga gcaaatccac aatcatcatg ttttcagaac ggtttttccc
     5341 gtcagcttgg agccagtcat gttcttgttg atccagccag ctattaaccc ctcgtttggt
     5401 ggtgcctttc ataggcctag tagttaacct gttgccctct tgtttaaaga acaattcagg
     5461 actagctgaa ataacggcaa actcatcatg ggcgatgtag gcattgtagc cagcagcctg
     5521 ttcaacgacg agtttattgt aaatggctaa actatcagct gcattgagtt cctgagttaa
     5581 ttgaagggtg tagttaacct gataagtatt gccctgttgc atctcacggt gaatggtttc
     5641 aatggctttt tgataggctt ctttttgagt tgcgctgacc cattggttag ggatagtaat
     5701 gctgtcataa tcaagaggta ggtctttttt ttgacaggtt ttgtgcactg taaaataggc
     5761 aaggtactcg ttgcctagtc tgtcattatg ggtttgtagg gcattgtcaa aaaaagcagc
     5821 tgcttcataa ctgagatagc ccaccacgta atagcccagc tgttggtagt gttgtacttt
     5881 ttcaatgact ggaccgacct gatctaagga cttggctacc aattctacta atggctcatc
     5941 aaaaagatag cgttgcccga gctctttgaa atcaataata gtttttctat gcatacccaa
     6001 attatatcat aaaagcggtt gctagaggtg atcctgccat taagaccttc tcttatggtc
     6061 aatattagtc aaatatgtta taattcagtt aataaaagtt ataacagtac gctcagcatg
     6121 tcaaagtaag taaactaatg aggtcttaca aagccttata cagcaacagt tagaaagatt
     6181 aggtataaaa aagatggcaa catacggctt tttatcagta ttagaagaag aaatggataa
     6241 gcattttcag tatgactatg ctatggattg ggacaagaaa aatcatgcgg ttgaagtgac
     6301 ttttgtgtta gaagctcaaa ataaagaggc tataaaaacc attgacgata gtggcgaagt
     6361 gacccaagat gatattgtct ttgaggacta tgtgctcttt tataaccctg ccaagtctca
     6421 atttgatgca gcagattatt tggttactat tccttttgac gctaaaaagg gcttttctcg
     6481 tgaattctta gcttactttg cgcaatttct caacgatgtt gctattgaag ggcacagcga
     6541 tttgatggat ttcttagcag atgacagcaa ggctgatttc ttcttggagt ggaacgcgca
     6601 agcttttgaa gaaggtcaac aaggactaga agaagcagca agttaccctt acccaaggta
     6661 ctaaggtgac acatgagatg gtgctaacac tattaggaca ataaccaaaa ggtcaaaata
     6721 gaaaggacat aactatggaa acgtggcaag aagtgacggt tcatgtgcat cgtgatgcgc
     6781 aagaggctgt ttcacatgtg ttgattgaga caggcagtca aggggttgct atcgcagata
     6841 gcgcagacta tattgggcaa aaggaccgct ttggggagtt atacccagat gtggagcagt
     6901 ctgacatgat agctatcaca gcctattacc caagtagtac taatttggcg gatattattg
     6961 cgaccattaa tgaacagtta gcggagttag ctagttttgg gttacaggtt ggtcaggtta
     7021 ctgtggacag tcaagaattg gctgaggaag actgggcaga caattggaaa aaatactatg
     7081 aaccagctcg catcacgcat gatttaacca ttgtccctag ttggacggat tatgacgctt
     7141 ctgctgggga aaaagtgatt aaactagatc ctggaatggc atttgggaca gggacacatc
     7201 ccacaactaa gatgagcctt tttgccttgg aacaaatcct tcgtggtggt gagacagtta
     7261 tcgatgtagg gaccggttca ggtgtcctct cgattgccag ttccttacta ggtgctaaaa
     7321 ccatctacgc ttatgactta gatgacgtgg ctgttcgagt ggctcaagac aacattgatt
     7381 taaaccaagg aacagacaac attcatgtgg ctgctggtga ccttttaaaa ggggttagcc
     7441 aagaagcgga tgtgattgta gccaatatct tggcggatat cttagtctta ttgactgatg
     7501 atgcttaccg tttggtcaaa aaggaaggtt accttatctt atctggcatc atttctgaga
     7561 aattggatat ggttctggaa gctgccttta gcgcaggctt tttcttagaa actcacatgg
     7621 ttcaaggtga gtggaatgcc cttgtcttta aaaaaacaga tgatatctca ggagtgattg
     7681 gcggctaatg caacagtatt ttattaaagg caaagcagaa aaaaaggtaa cgattaccga
     7741 taaagatacc atcaagcaca tgtttcaagt gatgcgcttg gctgacgagg ctgaagttgt
     7801 cttggtcttt gatgatgggg tgaagtattt agctaaggtg accaatagta tggctcatga
     7861 gttagagatt atagaggctt tgccagatca ggtggaattg cctgttaaag tgactattgc
     7921 ttctggattt cctaaaggcg ataagttaga cacgattgcc cagaaagtga ctgaattggg
     7981 agccagtgcg ctatggggct acccagcaga ctggtcagtg gtcaaatggg atggcaaaaa
     8041 attagctaaa aaagaagaca aattggctaa gattgtatta ggagcggctg agcagagcaa
     8101 acgaaatagg gtgcctgaag ttcacctttt tgaacataaa gcagagtttc taaaaagcct
     8161 ttctagcttt gatcatatct tcattgctta tgaggaaaca gctaaggcag gtcagctagc
     8221 gaccttggcg cgtgaagtaa aagaagttaa gccaggggca aaaatcctct ttatctttgg
     8281 accagaaggg ggaatttccc caactgaaat cactcagttt gaggcagcaa gtgccattaa
     8341 ggtgggctta ggccctcgca ttatgcgagc agagacagcg ccgctatatg ccttaagtgc
     8401 tcttagttat gctttggaat tgcaggcatc aaaataagta agctgttgct tactttagaa
     8461 agaagaggct aaagaaacgg acaggcagtt cacgattgtg tcaacggcct ttttttattg
     8521 cttcttgttt tttcgaagag cgttgatggg ctcatcacca aaaaaggaaa tgggctcttg
     8581 tcctcttttt ggtgagttat actactatat taatgaaaaa aaacgactaa catctgtcta
     8641 agaaaacgct ttacaaattg ttgcgaggct agtataataa aggtatcaga tcaatgcaag
     8701 cgattgcatc actgagttgc tgtctatatc attgtgtcac aaaagcgcct taagggcagc
     8761 tatggctaaa aggggataat aaaggagaga tagaatgaaa acatcattca agcaactgtt
     8821 tcgtttcgaa ttttggcaaa aatttgggaa atgtcttatg gtcgttattg ctgtcatgcc
     8881 agcggctggt ttaatgatca gtatcggaaa ctctattcca atgattaacc acgactcagc
     8941 atttttggca tctctaggca acattatcgc tcaaattggt tgggctgtta ttgttaacct
     9001 tcacttgcta tttgccttgg ccattggtgg tagttgggct aaagaaagag ctggaggggc
     9061 ctttgcctca gggcttgctt ttgtcttgat caatcggata acaggtgctt tttatggcgt
     9121 gtctagtact atgctagctg atccagaagc aaaaatcaca agcctccttg gcactcaaat
     9181 gatcgttaaa gattatttca ccagtgtctt ggaatctcca gctttaaaca caggggtttt
     9241 tgttgggatt attgcagggt tcgtaggagc aacggcctat aacaaatact ataattaccg
     9301 taaacttcct gaagttttga ccttctttaa tgggaagcgt tttgtaccat ttgtcgttat
     9361 tttacgttct atttttgtag cccttatttt ggttgttgtt tggccggtga tccagtctgg
     9421 gattaacagt tttgggatgt ggattgcctc ttcacaagat tcagctccaa tcctagcccc
     9481 attcctatat ggtaccttgg aacgtctctt gttgccattt ggtcttcacc acatgttgac
     9541 gatcccaatg aactatacag ctcttggtgg aacttatgag gtcatgacag gtgcagcagc
     9601 ggggacaaaa gtatttggtc aagacccttt gtggcttgct tgggtaactg accttgttca
     9661 ccttaaagga tcagacgctt cagcctatag tcacttaatg gatagtgtga ctccagctcg
     9721 tttcaaagta ggacaaatga ttggagctac cggaacattg atgggggttg ccttagccat
     9781 gtaccgtaat gtggatgccg ataaaaaaca cacatacaaa atgatgttca tctcagcagc
     9841 ggcagcggtc tttttgacag gggtaactga gccacttgag tacctattta tgtttgcagc
     9901 aatgccactt tacatcgtct atgcccttgt tcaaggagct tcatttgcca tggcagacct
     9961 tgtgaatctc cgtgttcact catttggaaa tatagagcta ctaacccgca cccctatggc
    10021 tcttaaagca ggcctaggca tggatgtgat taactttgtt tgggtttctg tcctctttgc
    10081 agttatcatg tactttattg cagatatgat gatcaagaaa atgcatctcg caacagctgg
    10141 ccgtttaggc aactacgatg ccgatatact gggtgaccgt aacactcaaa caagacctac
    10201 ccaagtagca gatagcaact ctcaagtcgt gcaaatcgtt aatctccttg gtggggcagg
    10261 caatattgat gatgttgatg cttgtatgac gcgcttacga gtgacggtca aagaccccgc
    10321 taaggttggt gctgaggacg attggaaaaa agctggcgct ataggcttga tccaaaaagg
    10381 caacggcgtt caagcggtct atggccctaa agcagatatt ttgaaatcag atattcaaga
    10441 tttgctggac tcaggtgctc ttattccaga agtcaatatg tcacagctca ctagcaaacc
    10501 gactcccgca aaagatttta aacacgtgac agaagatgtg ctatcagtgg cagacgggat
    10561 ggttctccca atcacaggtg taaaagacca ggtgtttgcg gctaagatga tgggagatgg
    10621 gtttgcggtt gaaccaaccc atggtaatat ctatgcaccc gtagctggcc ttgtgaccag
    10681 tgtctttccg accaagcatg cctttggttt actgacagat aatggtcttg aagtgctggt
    10741 gcacgtggga cttgataccg tcgccttaaa tggtgtgcct ttttcagtca aagtctcaga
    10801 agggcaacgg gttcatgcag gtgacctatt agtcgtagca gatcttgctg ctattaaatc
    10861 agcagagcgt gaaacaatca ttgttgttgc ttttaccaac acaacagaga tccaagatgt
    10921 gaccttgaca tctttaggag ctcagcctgc taagactaaa gtagctaccg tagaacttta
    10981 acaaaacatc acgagatagt gataggtaat agccatagct ggtttaggcc ctatggctct
    11041 tcttgtctta taaaggagga ttaatgacca aggtattaac actgaatacc cattcgtgga
    11101 tgcaagccaa cactcttaaa aaattagttg ctttggctga gcatatttta gctgaaaaat
    11161 acgatatcat ttgcttgcaa gaaatcaatc agttaatcga gagcgagctg gccacagatt
    11221 taccaagata tcaagctctt tcagggacac caagcattca taaagaccat tttgcccttc
    11281 tcttgatcca ttatttacaa aaacgagggc agcactatta ttggtcttgg gcttataacc
    11341 atattggcta tgacatttac caggaaggcg tggcaatctt atcaaaacaa cctattcatg
    11401 tttcagatat tctcgtgtca gcgatggatg atgaaacaga ctaccacacc agacgctcac
    11461 tcatagccaa aaccacgtta gatggcaaag aagtcgctgt tgtcaatgtg cacctatctt
    11521 ggtttgacaa ggggttttta ggggagtggg agaaattaga aaaagaactg ctcacactaa
    11581 actgtccctt gctacttatg ggagatttta acaatccaac ggatcaagac ggttatcaag
    11641 tgatgatggg tagcccccta gacctacaag atagccataa gggtgctgac cacgtgtttg
    11701 gtgatcatag catcgtggct gatattgatg gctggcaagg taacaaagaa gccctcaagg
    11761 tggaccatgt ctttaccagt aaggacttca tcatccgatc ttctaagatt acctttgaag
    11821 gcggagatgc gccagtcgtc agtgaccact atggtctaga agtgacatta ggctggcgtt
    11881 agagcatgtg ctaacaggca caccacataa gagaagccaa gacacataag aaactgcgat
    11941 catctagggg ggattaggag aacacaaaga ggtctaacca gctcaaggta gagctggtta
    12001 gacctcttta gtcatgtcag taaccccaga aaaccagggc ttttttgtca ccaaccatct
    12061 gagcttcaca gaaagtacca ccaagcgttc agttgccttg ctaaagtctg catgggggta
    12121 tttctaggag tgcttggtgt gatcccaagc cccaagaagc actgtgatcg ctcttttcaa
    12181 aggctgagaa atcacaaggc gtggggtagg gccctctgta gttattgtcc taaaagcgct
    12241 cttttttaaa acagctatga tcatctatgg actgtctagc tgttaggcag tgtctgtgtg
    12301 tcgttagacg agtgtctgga gctggcctcc atgatgacct gggctaaccg cgaaatgtca
    12361 tcaggagtcc ctcgcagctc aaaatcacct agcagtggaa agccaaagcg tttggcatac
    12421 tgtttggctg tcaggcaata ctgatggtta aagtttttgt tgcctgagcc aataatccca
    12481 agacaacgct gggcgttgcc atgggcagca ataaactctc ccaaaggagt ggtgaggatc
    12541 tccacatcac cagagtcaac gccatttccg ccttctagat aagtgggtaa aatcgccaca
    12601 aactcttcct tgacgggaaa agtctcgtgc ttcaaatctt taatgttaat ctgtttgaca
    12661 tggtaatcgt aattgtctgc tagataaagg gatagccgct tgacaaagct aagggtgttg
    12721 ccactgaggc taataaaaac aagggtaatc tgaggcataa gtgtctcctt tttttatcct
    12781 acaaggtttc ttcataagct taccacaatc aagaccaaca aacaagtaaa gaagaaacct
    12841 agcggtatcc aaccagacaa gaaggtacaa gcagtcaaaa aaagtaacat ttcaaaaaag
    12901 agtgacctta aagaaaggat ccggatgccc tcgacttaaa aacgaggcag gcaagtgcca
    12961 aagtagccct ctgatctcca caaaagagtg atcagtcaaa atctaaaaga tgaacaacaa
    13021 aagagaactt tacaatcgtt ttcacactct attataatac tattataaat aatcaggtct
    13081 agctaccatg ttatttttat ctaaaacaca ccatctaata aagaaagaga gaacaacata
    13141 tgttgacatc aaagcaccat aatctcaaca aactagtctg gcgctacggg ctaacctcag
    13201 ccgctgccgt ccttctagcc tttggaggcg gggcaagcag cgttaaggct gaggtttctt
    13261 ctacgactat gacgtcgagt caaagagagt caaaaataaa agagatcgaa gaaagtctta
    13321 aaaaatatcc agaagtgtcc aatgagaaat tttgggaaag aaagtggtat ggaacctatt
    13381 ttaaagaaga agattttcaa aaggagctaa aagattttac tgagaagagg cttaaggaga
    13441 ttctagattt aattggtaaa tctggaatca agggagaccg tggtgagact ggtcctgctg
    13501 gcccagccgg accacaaggt aaaactggtg agaggggcgc ccaaggtcct aaaggtgacc
    13561 gcggtgagca aggaatccaa ggtaaagctg gtgaaaaagg tgagcgcggt gaaaaaggcg
    13621 acaaaggtga aaccggtgaa cgcggtgaaa aaggcgaagc tggaatccaa ggcccacaag
    13681 gtgaagctgg taaagatggc gctccaggta aagatggagc tccaggcgaa aagggtgaaa
    13741 aaggtgaccg cggtgaaacc ggagctcagg gtccagtagg cccacaaggt gaaaaaggtg
    13801 aaacgggcgc ccaaggccca gcaggcccac aaggtgaggc aggcaaacca ggtgagcaag
    13861 gcccagcagg cccacaaggt gaagcaggcc aaccaggcga aaaagctcca gaaaagagcc
    13921 cagaaggcga agcaggccaa ccaggcgaaa aagctccaga aaagagcaaa gaggtaactc
    13981 cagctgcaga aaaacctgct gacaaagaag ctaaccaaac gccagaacgc cgcaatggca
    14041 atatggctaa gacacctgta gccaacaacc acagacgtct accagcaact ggtgagcaag
    14101 ccaacccatt ctttacagca gcagcagtag cagtgatgac aacagctggt gtcctagccg
    14161 ttacaaaacg caaagaaaac aactaattct ctgaattgag agaccttact gataagcaaa
    14221 cataatagag agagcccctt ggttctctct atttttggtc gggagcaggc ctttggtatc
    14281 atgctcacgc ctgagagatc ccaaaagata tcaaaagcag ctcactaacc gttttctaag
    14341 aaaaggtcac actaagcgct ttcttagcag attctgcctt ttgcttttgt gtgtaaagtg
    14401 ttaaaatagg gaaaagaaat gctagatgag gaacgaaatg gcaaaaataa tgaacgtaac
    14461 aggagaagaa gtcattgcct tagcggccac ctatatgacc aaggctgatg tggcttttgt
    14521 ggcaaaggct ttagcatatg caacagcggc ccatttctac caagtgagaa agtcaggcga
    14581 accctatatc gtccatccga ttcaggtggc ggggattctg gctgatttgc atctggatgc
    14641 tgtgacagtt gcttgtggct ttttacatga tgtcgtagaa gatacggata ttaccttaga
    14701 tgagatcgaa gcagactttg gccatgatgc tcgtgatatc gttgatggtg tcaccaagtt
    14761 aggtaaagtt gagtacaaat ctcatgagga gcaactcgcc gaaaaccatc gcaaaatgct
    14821 gatggctatg tccaaagata ttcgcgtgat tttggtgaaa ttggctgacc gcctgcataa
    14881 tatgcgcacc ctcaaacatt tgcgcaagga caaacaagag cgcatttcgc gcgaaaccat
    14941 ggaaatctat gcccccttgg cgcatcgttt ggggattagt cgcatcaaat gggaactaga
    15001 agatttggct tttcgttacc tcaatgaaac cgaattttac aaaatttccc atatgatgaa
    15061 agaaaaacgt cgcgagcgtg aagctttggt agaggctatt gtcagtaagg tcaaaaccta
    15121 tacgacacaa caagggttgt ttggagatgt gtatggccga ccaaaacaca tttattcgat
    15181 ttatcggaaa atgcgggaca aaaagaaacg attcgatcag atttttgatc tgattgccat
    15241 tcgttgtgtc atggaaacgc aaagcgatgt ctatgctatg gttggctata ttcatgagct
    15301 ttggcgtccc atgccaggcc gcttcaagga ttatattgca gctcctaaag ctaatggcta
    15361 ccagtctatt cataccaccg tgtatgggcc aaaaggacct attgagattc aaatcagaac
    15421 taaggacatg catcaagtgg ctgagtacgg ggttgctgct cactgggctt ataaaaaagg
    15481 cgtgcgtggt aaggtcaatc aagctgagca agccgttggc atgaactgga tcaaagagct
    15541 ggtagaattg caagatgcct caaatggcga tgcagtggac tttgtggatt cggtcaaaga
    15601 agacattttt tctgaacgga tttatgtctt tacaccgaca ggggccgttc aggagttacc
    15661 aaaagaatca ggtcctattg attttgctta tgcgatccat acgcaaatcg gtgaaaaagc
    15721 aacaggtgcc aaagtcaatg gacgtatggt tcctctcact gccaagttaa aaacaggaga
    15781 tgtggttgaa atcatcacca atgccaattc ctttggccct agtcgagact gggtaaaact
    15841 ggtcaaaacc aataaggctc gcaacaaaat tcgtcagttc tttaaaaatc aagacaagga
    15901 attgtcagtg aataaaggcc gtgatttgtt ggtgtcttat tttcaagagc agggctacgt
    15961 tgccaataaa taccttgaca aaaaacgcat tgaagccatc cttccaaaag tcagtgtgaa
    16021 gagcgaagaa tcactctatg cagccgttgg gtttggtgac attagtccta tcagtgtctt
    16081 taacaagtta accgaaaaag agcgccgtga agaagaaagg gccaaggcta aagcagaagc
    16141 tgaagaattg gttaagggcg gtgaggtcaa acacgaaaac aaagatgtgc tcaaggttcg
    16201 cagtgaaaat ggagtcatta tccaaggagc atcaggcctc ttgatgcgga ttgccaagtg
    16261 ttgtaatcct gtacctggtg atcctattga cggctacatt accaaagggc gtggcattgc
    16321 gattcacaga tcggactgtc ataacattaa gagtcaagat ggctaccaag aacgcttgat
    16381 tgaggtcgag tgggatttgg acaattcgag taaagattat caggctgaaa ttgatatcta
    16441 tgggctcaat cgtagtggtc tgcttaatga tgtgctccaa attttatcaa actcaaccaa
    16501 gagcatatcg acagtcaatg ctcagccgac caaggacatg aagtttgcta atattcacgt
    16561 gagctttggc attccaaatc tgacgcatct gaccactgtt gtcgaaaaaa tcaaggcagt
    16621 tccagatgtt tatagcgtga agcggaccaa tggctaagaa aggataaaaa catgaaactt
    16681 gtcttgcaac gggtcaaaga ggcctctgtt tctattgatg ggaaaattgc tggcgctatt
    16741 aatcaagggt tgttgttgtt agtaggtgtg ggaccagatg ataatgcaga agatttggct
    16801 tacgctgtgc gaaaaatagt caacatgcgc attttttcag atgctgatgg caagatgaac
    16861 cagtctatcc aagacatcaa gggcagtatc ttatctgtgt cgcaatttac cctttatgct
    16921 gacaccaaaa agggaaaccg tcctgccttt actggtgctg ctaagccaga tttggctagt
    16981 cagttgtatg atagctttaa tgaacaattg gcagagtttg tgccagttga gcgtggcgtt
    17041 tttggggcag atatgcaggt tagtctcatc aatgatggac cagttacgat tattttagac
    17101 acgaaatgtc actagtctct acaactaaga ggttagaaaa aagcaagcaa ctgttgatag
    17161 cgtgttgctt gctttttttg tcagttaatc tcatcatttt agaagatcgt ggttatttgt
    17221 ctttagggtt atcaggtata ggtgtccctg tatcacgcag gtagctgtaa gcttttcgtt
    17281 cttcttcggt atagagatct ttatcataag ctaaatgata gctacccttt gcccctttag
    17341 ggcgcttgcc catataaact gtaacgacac gattattctt atcgtgatta tcctctactt
    17401 ttccagttaa ggtatagtcc atgatatcaa aagcatcgag attgttgtag agtagtttag
    17461 ccttatcacg aggatcgtat aaatctctga agtctaagtt acgttcgcta gctgttaaga
    17521 gctgctcgct ttttagcaat tcgttggtgt tgacatcaac gtatttgatg gtgaacagtt
    17581 tcaagtgact gcgatcaaag ggatcatacg gcttttcccc ttgtttaagg acgtaatatt
    17641 tctcagagac cagatcagtg ttgttcgttt tttctttaat acctgtttta ggattgatct
    17701 cataagcttg ttcccgattt ttgacatggt aagtaaactc ttgatccatt ggtaaaatcg
    17761 tacggaaaat gtcattgtca tgagtgacga ttgaggagtc acgttcataa atcgtatagc
    17821 ctgggtgggt tttgtttaaa atgctttgtg cttgagctag taattcttga gatgtgatgg
    17881 tgtcaccgat agctagtgtt ttcaatagct tagtatcttt gagccctggt ctgaaatcgt
    17941 catcagggtt taaaggagta aactgtacag tatattctac atcaacagat tttgcttgat
    18001 tttgtactgg tttttcttta tatggtctaa cgcgcacatg tccctttaac aaaaattctt
    18061 ggacaggttg ggtcggcaag gttaccgaac catctttgtc agcaaagtag accttgccgt
    18121 ttcgatcagt aatggttgca tcgcttgcaa aatcaatgac ctcaaagtag ccgtcgttac
    18181 tgtgaacgtt agcgatcagc tgtttttgaa tagcttttaa taagtcagct ttttcaagtt
    18241 tatgtggcat tgcgccatta tctgtagcaa atggttttga ttttggactt aagccctgct
    18301 ctgtctttcc tccgtgagca ggttgtgatg ttagatcgat ttcaaaaaaa tttataaaaa
    18361 cttttttatc ggtaccttca acgataccgg ccatactaac aactaactgg ctgttattga
    18421 taggtggacg gtctggtagc catccatacc cagcaatagc ttggaccgac ttgactgttc
    18481 caaatgttaa tgcaaacagc agtgcaatca ctccaataga taagtaattt ttcatagaaa
    18541 cctcctaaaa gttaagtttc aatccccatt attagaataa cataataatt ttatagatac
    18601 aaacaaa
//
LOCUS       DAUGQX010000038        17559 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUGQX010000038 DAUGQX010000000
VERSION     DAUGQX010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17559
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.038"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            50..1393
                     /locus_tag="VIA51_001337"
     CDS             50..1393
                     /locus_tag="VIA51_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEQ8683278.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     ERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFVCLNCQFQRPTLDYQLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTVGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI"
     gene            1393..2184
                     /locus_tag="VIA51_001338"
     CDS             1393..2184
                     /locus_tag="VIA51_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEQ8683279.1"
                     /translation="MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(2293..3282)
                     /locus_tag="VIA51_001339"
     CDS             complement(2293..3282)
                     /locus_tag="VIA51_001339"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8683280.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILAKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            3515..5932
                     /gene="hylA"
                     /locus_tag="VIA51_001340"
     CDS             3515..5932
                     /gene="hylA"
                     /locus_tag="VIA51_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEQ8683281.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASANITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIKADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTSVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTG
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKYPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYGKKATMFSNHNLSHQGFYSFPH
                     PVRQNQQ"
     gene            complement(6159..6296)
                     /locus_tag="VIA51_001341"
                     /pseudo
     CDS             complement(6159..6296)
                     /locus_tag="VIA51_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(6606..8369)
                     /gene="lpdA"
                     /locus_tag="VIA51_001342"
     CDS             complement(6606..8369)
                     /gene="lpdA"
                     /locus_tag="VIA51_001342"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEQ8683282.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVS
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAM
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(8696..10105)
                     /locus_tag="VIA51_001343"
     CDS             complement(8696..10105)
                     /locus_tag="VIA51_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEQ8683283.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPAVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGANKMCLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVSRPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(10290..11288)
                     /locus_tag="VIA51_001344"
     CDS             complement(10290..11288)
                     /locus_tag="VIA51_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEQ8683284.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(11347..12315)
                     /locus_tag="VIA51_001345"
     CDS             complement(11347..12315)
                     /locus_tag="VIA51_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEQ8683285.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGVPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(12600..14507)
                     /locus_tag="VIA51_001346"
     CDS             complement(12600..14507)
                     /locus_tag="VIA51_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8683286.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQVLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPNGLDRYSGNYSRFMALKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTGGRKSAHMTFHAEKPSGNVVLRVEEAAI
                     GYGDQVLSEPINVDINKLDAIAVVGPNGIGKSTLIKSIIGQLPLLKGQLKYGANVETG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQEALME
                     EWETIAEQIES"
     gene            complement(14553..14879)
                     /locus_tag="VIA51_001347"
     CDS             complement(14553..14879)
                     /locus_tag="VIA51_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683287.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(14909..15694)
                     /locus_tag="VIA51_001348"
     CDS             complement(14909..15694)
                     /locus_tag="VIA51_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEQ8683288.1"
                     /translation="MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGK
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(15827..17488)
                     /locus_tag="VIA51_001349"
     CDS             complement(15827..17488)
                     /locus_tag="VIA51_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8683289.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIIYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
BASE COUNT         5289 a         3701 c         3093 g         5476 t
ORIGIN      
        1 aaagattttt ccctatctaa aatcaataaa cttatgataa aatataagca tgaaaatgaa
       61 gacattactc ggcattattg ctggcaaagc tgctcaatcc attttaacaa aactagggcg
      121 aggatctact tatcctggtc gattggctct agcttgtgat aaagatattt taaaggattt
      181 gtctaaagac tatgatattg tggtcgtcac tggtactaat ggtaaaacgt taacaactgc
      241 tcttactgtc ggtattttga aagaggcatt tggcgagata atcacaaatc caagtggtgc
      301 caatatgatt actggaatta cttctacttt tttagctgct aaaaaaggga aatctgaaag
      361 gcaaattgct gttttagaaa ttgacgaggc tagtcttcct agaattacca cttacttaaa
      421 acctagtctt tttgtttata ctaatatttt tagggatcag atggaccgct acggagagat
      481 ttacactact tatcagatga ttgtagatgg tgctcgaaat gctccaaaag caactattct
      541 agccaatgga gatagtccta ttttctcttc taaggacata gttaatccag ttcagtatta
      601 tggttttgat actgctaagc atgctccgca gctagctcat tacaacacag aagggatttt
      661 atgtccaaaa tgcgaacata ttcttcagta tcgtctcaat acttatgcga atctaggaga
      721 ctttgtttgc ttaaactgtc agttccaaag accaacgtta gattatcaat taactgagct
      781 caccgctatt actcaccaaa gttctgaatt tgttattgat ggacaaaact acaagataaa
      841 tgttggtggt ctttataata tttacaatgc gctcgctgcc gtctctgttg ctgaattttt
      901 cggtgtttct cccgagaaaa tcaaggcggg ctttaacaaa agtaaggcgg tttttggaag
      961 acaagaaact tttactgttg gtgataaatc atgcaccctt atccttatca agaatcctgt
     1021 tggagccagt caggcactgg aaatgattca attggcagat tatccattta gcttatcagt
     1081 tttattaaat gccaattacg ctgatggcat tgataccagc tggatttggg atgctaattt
     1141 tgaactcatt acccaaatgc ccattacaga aattaatgct ggcggcgtcc gccactctga
     1201 aattgctaga agacttagag tcacaggatt tgacgatact aagataaaac aagctgaaaa
     1261 gctcgagcaa atcatagaaa ccattgaaaa acaagaagct aagcatgcct atattttagc
     1321 aacctatacg gcaatgttag aattccgtag cttacttgct gaccgccatg tcgttgaaaa
     1381 ggagatgatc taatgacata cacttcacta aaatctcccg aaaatcaaga ttacatctac
     1441 gacctcacta tcgcccatct ctatggtaat cttatgaata cttatggtga taacggcaat
     1501 attttaatgc tcaagtatgt cgctgaaaaa cttggagcta gggtcactgt tgatattgtg
     1561 tctatcaatg atacctttga acaagacgat tacgatattg ttttctttgg tggtggtcaa
     1621 gattatgaac aaagcattgt tgccaaggat ttgcctagca aaaaagctgc cttagcggat
     1681 tacattgcta ataataaagt ggtgcttgcc atctgtggtg gcttccaatt actagggcaa
     1741 tactatgtcc aagctaatgg ggttaaaatt gatggacttg gaattatggg acactacacc
     1801 cttaatcagc accaaaatcg ctttattgga gatattaaaa ttcataatga cgaatttaac
     1861 gaaacctatt atggctttga aaatcatcaa ggacgtacct tcttatctgg tgacgaaaag
     1921 ccacttggac gagtggttta tggcaacggt aataataaag aagaccaaac tgaaggtgtt
     1981 cactataaaa acgtctatgg tagttatttc cacggtccta tcttatcacg caatgttaat
     2041 cttgcttacc gcttagtaac aacagctctt aaaaaaaagt atggatcagc tatttcacta
     2101 cctagctatg atgatatact gaaacaagaa atcactgaag aatatgccga ccttaaaagc
     2161 aaagcttcct ttaataaagt ttaagttctt ctttcatgtc atcaaacaaa aactcctaag
     2221 taggacacga tagttcgctt aggagtttta tagttttttc ttctgacaga gcttcttaag
     2281 tgattaaaac cactaagaaa caatagcttt agcaacttct tcaacggtca tgcgtgagaa
     2341 gtactgggtc gtatcaatcg tttttaaacg ttcaaaaaca tcacggtact catatttaca
     2401 accaattaat aagttctcaa tgtcttgcac atctttgatt ccaaagaaat caccatagat
     2461 tttaaggttt ttaatgatag aattttcaac atttgcaaag gttgaaattt tacctgcagg
     2521 gtaacgaaca ttgcgttcaa tcgtatattc tggcgctttg ccgtaggtcc aatcccagct
     2581 accaaattgc tctttggcag attgttcaat cttagccaac tcatcctctg acaagacata
     2641 ttctgtcatg tctgggtacg tttctttcat cttggccaag attttatctg aaaattcctc
     2701 aacggtaatt ttttctggta attcatttaa aatattggtc acgcgagcac gaacagactt
     2761 cactccttta gactcaatct tgtccttact taccttaaga gcatcgccaa gaacggtcat
     2821 atccacatca aacaaaaggc aaccatggtg catcatgcga cctttgtagt aagcttgagc
     2881 attaccgcag atttttttac catcaatttc aatatcatta cggcctgtaa agttggctgt
     2941 tacacccaaa tcagctaaag tcgcaatcac aggttgtgag aaggttttga aatcaaatgc
     3001 gccttccgct gttttatttg aaatgatagt gtagttcaag ttattcaaat catgataaac
     3061 cgcaccacca ccagataaac gtcgcacaac atgaatacca tgttcatcaa tgtattcttt
     3121 attgatttct tgaatggtat tttgatgttt gccaataata atagctggct cattgatcca
     3181 aaggataaac aattcgtctt cttccactag ttctctaaaa gcataggctt ccaaagcgat
     3241 gttaaaggca ggattgtgac ttttgttaac gatgtatttc ataggagaaa aaatcctttc
     3301 aaaaatgtaa tctacctctc tagtataatg aaaacaaata taaaagacaa gtgtcctatt
     3361 ctgtatgaca tcttcagtac ctacacttat tagtgcacaa aaactcagcc attatttatg
     3421 taagggttta taaaaatact ttaacgtggt atatttttac ttagtaaatc aatttacttt
     3481 tattatctca tttttatatt ggaggaattt atcagtgaat acttattttt gcacacacca
     3541 taaacaatta ctactttatt caaacctatt ccttagcttt gctatgatgg gccaaggaac
     3601 tgccatttat gccgatacac tgacttcaaa ttcagaacct aataatactt actttcaaac
     3661 gcaaacgctc actactacag atagcgaaaa aaaggtagta cagccacaac aaaaagacta
     3721 ctatactgaa ttgttagacc aatggaacag tattatcgca ggcaacgatg cttatgataa
     3781 aaccaatcct gacatggtca cttttcataa taaagctgaa aaggatgctc aaaacattat
     3841 taaaagctat caagggcctg accacgaaaa tagaacttac ctttgggaac atgcaaagga
     3901 ttattccgct tctgctaata tcacgaaaac ttaccgcaat attgaaaaaa tagcaaaaca
     3961 gatcactaat cctgaatcat gctattatca agatagtaaa gctattgcta ttgtaaaaga
     4021 cggtatggcc ttcatgtatg aacacgctta taatctagat cgtgaaaatc atcaaacaac
     4081 tggaaaagaa aacaaagaaa attggtgggt ttatgaaatt ggaactcctc gtgctattaa
     4141 taatacctta tccttgatgt atccttattt tactcaagaa gaaattctta aatacacagc
     4201 tccaatcgaa aaatttgtgc ctgaccctac tcgttttagg gttcgcgctg ccaatttttc
     4261 accttttgaa gccaatagcg gaaatttaat tgatatgggg cgtgttaaac tcatttccgg
     4321 tattcttcgt aaagatgatc tcgaaattag tgatacaatc aaagcaattg agaaagtttt
     4381 cacgctagtt gatgaaggaa atggttttta ccaagacggt tctttaattg atcacgtggt
     4441 tactaacgct caaagtccac tttataaaaa aggcattgct tacactggag cttacggtaa
     4501 tgtgcttata gatggcttat cgcaattaat tcctattatt caaaaaacaa agtctcctat
     4561 aaaagcggat aaaatggcta ctatctatca ttggattaac cattcttttt tccctatcat
     4621 cgttcgtgga gaaatgatgg atatgactcg agggcgttct atcagtcgtt ttaatgccca
     4681 atctcatgtt gctggcattg aagcacttcg tgctatttta cgtattgctg acatgtctga
     4741 agagcctcac cgtttggcac ttaaaacacg tataaaaaca ctcgtcacac aagggaatgc
     4801 tttttacaat gtctatgata atttgaaaac ctatcacgat atcaaactta tgaaagaact
     4861 actaagtgat acttctgttc cagtccaaaa acttgatagt tacgtagcta gtttcaatag
     4921 tatggataaa ttggcactat ataataataa acacgatttt gcttttggcc tatcaatgtt
     4981 ttcgaatcga actcaaaatt atgaagctat gaataatgaa aatcttcatg gctggtttac
     5041 ttctgatgga atgttttacc tatacaataa cgatttagga cactacagtg aaaactattg
     5101 ggcaacggta aatccctacc gcttacctgg aaccacagaa actgagcaaa aaccactaga
     5161 gggaactcct gagaatatta aaacgaacta tcaacaagtt ggcatgactg gtctctctga
     5221 tgacgctttt gttgcaagta aaaaacttaa taacacaagt gctctagctg ctatgacctt
     5281 cactaattgg aataaaagcc tcaccctcaa taaagggtgg tttatcttag gaaacaaaat
     5341 aatctttgtt ggtagcaata tcaaaaacca atcatctcac aaggcgtata caactattga
     5401 acaacgaaaa gaaaatcaaa agtaccctta ctgttcttat gttaacaatc aacccgttga
     5461 cttgaataat cagctagttg attttacaaa cactaaaagt attttccttg aaagtgatga
     5521 tcccgctcaa aatattggtt actacttctt caagccaaca acacttagca taagtaaggc
     5581 acttcaaaca gggaaatggc aaaacataaa agctgatgac aaatcaccag aagccatcaa
     5641 agaagtttca aataccttta tcactatcat gcaaaaccat actcaagatg gcgatcgtta
     5701 tgcctatatg atgcttccaa atatgactcg tcaagaattt gaaacctata ttagcaagct
     5761 tgatatcgac ttattagaaa acaatgacaa actggccgct gtctacgatc atgatagtca
     5821 acagatgcac gtcattcact atggaaaaaa agcaacgatg ttttcaaatc ataatctttc
     5881 tcatcaaggc ttttatagtt ttcctcatcc tgtcaggcaa aatcaacaat aaaagcttgc
     5941 tgatcaagga attgcagcta aaaacaatgc tcttaactct cataaaattc cccacaaaag
     6001 acaacgacgc ttaccgcata ctgggtatca gtcctcctct ttagaattct taggtggagc
     6061 tttagttgct tcttttaacc atatcacaaa accctttcgt aagaaagact taaggattta
     6121 gctgttattg gaaagtaagg gttaacaatg aaacgttatt aaagacaaaa aactagaaac
     6181 tgcactgagc cccaaaagtt ggctactcta tttgaagtaa aggatttagt tctgtattgt
     6241 agaggactaa gtccttttcg ttttattttg atacgtttat tgttgcaata atcgatgata
     6301 atagtaggta gaacgagtca atttagccgt ccttaaaaga aaatctaatc agaactcgtc
     6361 tttatccatt ctttataatg gttttttgtc ttcttctttt cagagatgct tctttcaaac
     6421 ggagttctct cggttttttt agcgctaaat gtctagctta tcttcatagc ttaatgtcat
     6481 acaaaaacac cccaaacgtt agggttttat atctaacgtt tggggtgcag ttcatagttg
     6541 tgctagtctt ttttgtgatc tgttatgtga tgatattttt cattagttaa taagacaaag
     6601 acgttttact tacgttttgg tgggttatgg atagcttcgc caagcacatc tgcaaaggct
     6661 tcgtacatca cttcagagaa ggttgggtgt ccatgaattg ataataacaa ttcatcaacg
     6721 gttaattcag attccataat agtagctgct tcgttaatca tctcagctgc agctggacca
     6781 ataatatgaa cacctaagat ttcgtggtat ttggcatcag caataacttt aacaaaacca
     6841 tgtgcttcat ttgaagcaat cgcgcgtcca ttaccagtaa agctgttttt accaataagc
     6901 acatcaccat attgttcacg cgcttgttct tcagttaaac caaccattgc cacttcaggg
     6961 tgtgtgtaaa cagctgctgg agtgtattta aggttagctt tacgagttgt gttgccatgc
     7021 atcgcatttt ctgcagccac ttcacccata cggtaagcag cgtgagcaag cattttcgtt
     7081 ccgttaacgt cacctggcgc atagatacct ggaattgatg tctcttggta gtcattaact
     7141 ttgatacggt tacgatccat ttcaaggtta agattttcca gaccgttcat ttgtgataca
     7201 cgtccgatag aaagaagagc tttttcagca acaacttctt caccattgtt aagtttcaaa
     7261 gtcaattggt tatttgcttc aacaatttca gagacaccaa cagatgtttt gatcttcatg
     7321 cctttcttag aaaggatttt ttgaagttca agagagactt ctttatccat agctgggata
     7381 atacggtcag ccatttcaat aacggtaaca tccacaccgt aagatgccca aacaagtcca
     7441 agctcgatac caacaacacc accgcccata actgctagtg attttggcat ttcacggagg
     7501 tcaaggatat catctgacgt taagacaagt ttagagtcaa tacctgggat attgatacgt
     7561 gatactttag aacctgtagc aaggataacg ttgcgaccct taatggtttg tgacccaatg
     7621 gttacagtct tgtcagggtt gacttgacca agcccattaa agatagtgac tttattagct
     7681 tttagaagac cttgaacgcc gcctgttaag gttttaacaa cggtgttttt aaagtcaact
     7741 gttttgtcca tgtcaatagt atagttagtt gaggcaaggt taatcccacg tcctgctgca
     7801 atcttaatac catcaaggat ttcagcattt ttaaggtaag ttttggttgg gatacaccct
     7861 acgttcaagc aagttccacc aaattcagat ttctcaacga tggcaatttt accaccaagt
     7921 tgagcaccac gaatagctgc ataataacct gcagggccac caccaacaac gatgatgtca
     7981 tactcatcat cagcaagtgc agcttttggt gcagctgaag cagcttgagc tggtgctttt
     8041 ggcacttcaa gtccagcagc ttctaaatct tctgttgtac gagcaacatt cacatctgaa
     8101 gcagctgggc tagaaacctc aacagattca ccttcagcac cgatatatcc gataacttct
     8161 gttacaggta ctgtttcacc tgcttgacgt gtaattttaa gaagaacacc tgagtcttct
     8221 gcctcaagtt ccatattggt tttatctgac atgatttcaa gaagaatatc gccttcattg
     8281 acagtatcac cttcttgttt tttccactcg atgatttcac cttcttgcat gtcaacaccg
     8341 agttttggca taataatttc aacagccata atttaagata ccaagagcaa ggagaaagcg
     8401 attgaatttt tgcggtaagt cagaaatctt tgatttcgtt gacgcaccca cgtcaggacg
     8461 actaggactt tccgaaacaa aaactgagga aagttcagac gtctacgacg ctaagattag
     8521 ccaactctta ccatttttat ccgagctttt cgctcggatt caattgctta tcactcattt
     8581 gcatgagagc tcctcgttct acatcctttc tatatttttg agaaaagggc accaagtcta
     8641 aacttagcaa aatccctttt attattgaat gcttttcttg tttaaaactg attgatcaga
     8701 ttaacaattc aaatggattt tccatcaatt tcttgagatc aaccatgaat tttgcaccgt
     8761 tcataccatc aactaaacgg tggtcgatgg ttaggcacat tgccataatt ggacgggaaa
     8821 caatctcacc atccacaacc gttggagttg ggatagttgc tccaacacca agaattgctg
     8881 agtttggttg gttaataatt gggttaaatg tcttcgtacc aaacattccc aagtttgtga
     8941 tagagaaggt tgatccagac atttcagctg ctttcaactt accagtttgc gcttttttaa
     9001 tcacatcttt tgaagcaagc acgaaatctg acaagcacat cttgttagcc ccatggataa
     9061 caggaacgat aagaccatca tcaagaccta cggcaatacc aaggttcaca aagcggtgca
     9121 attcaatatc attagcatca ttgatgaggg aagcattcat gtactcatgc tcaggtttca
     9181 tcaaggtttt aaccactgcc ataccaatca agtctgtaaa gctgacttta aggcctgttt
     9241 tagccatgat tgggtcaatt aacttcttac gaagggcaat catctctgtc atgtcaatat
     9301 cgtagttaag cgtaaaggta ggggcagtaa ggtaagagtt tgtcatacct ttagagattg
     9361 ccttacgcat agctgacatt ggcttgtgtt ccacaccttc tggaagatca acaacttttt
     9421 cttctttagc tgctggggct tttgcttcag ctggtttagc cgcttcaaga atagccatga
     9481 tgtcttcttt catgacctta ccgttaaagc cagtacctga tacggttgcc aaatcaatac
     9541 ctttgtctgc tgcaatttta cgagcaagtg gtgaagcttt cggttgagca cctttaaagt
     9601 tttcaacgtc ttctttatgg acacgtcctt ttggtcctgt tcctggaact tggccaaggt
     9661 caatgcccat ttctgctgct gccttacgtg cagctggagt agcacgaact tttccgccat
     9721 ttccttgcgg aatagctgtc gctgccactt gaggagctgg acttgccaca ttttcttttg
     9781 gagcaactgc tggtccagcg tctgctgaag caggaactgg aatttctgtt gttttttcac
     9841 ttgaagcaat agtatctact gattcaccct ctgcaccaat gtaaccgata acttcagtta
     9901 caggtacagt atcacctgct tgacgtgtaa ttttaagaag aacacctgag tcttctgcct
     9961 caagttccat attggttttg tctgacatga tttcaagaag gatatcacct tcattgacgg
    10021 tatcaccttc ttgttttttc cactcgatga tctcgccttc ttgcatgtca acgcccagct
    10081 ttggcataat aatttcaaat gccatttcta catcctttca cgatttgata agcgccatca
    10141 acatcctcac cttgctacga aaacatacga aaggtgaggt gccgcgacac gggataagac
    10201 aactcagttc ttctaaaaac tttcaaaata gtttttagct gagacgttac tgataaacat
    10261 agcctttatc ggaccacttg ccttatcttc tagttgcctt tgtttgccat tttcacaata
    10321 gcagctttga ttttctcaac atctggtaag attgcttgtt caagtacacg agcataaggt
    10381 actggaacat cttcacttgc aagacgaacg attggatgat caaggtaatc aaaggcttca
    10441 ctttcggtaa tcatggttgc aatttcccca atgaatccac cggtcttgta ggcatcgttg
    10501 acaagcatca atttacctgt tttcttaaca gattcaataa tcaactcttt atcaagtggg
    10561 atgagggtac gtgggtcaac aacttcaacg ttaataccat ccgctgctac ttcttcagcc
    10621 gcttgaagaa cacgctccaa catacgaccg tatgacacaa ttgtcaaatc agttccttca
    10681 cgtttgatgt cacctttgcc aagtgggata tagaagtcag gatcttggtt aacttcttct
    10741 tttttaccat aaagcgcttt tggttccatg aaaagaacaa tgttattatc acggatagct
    10801 gattttaata agcctttagc atcgttggca ttaccaggag caacaacttt gattcctgga
    10861 atgtgagtca accatgcctc aagagattgt gagtgttgcg cagcggaacc aataccagaa
    10921 cctgatgcca cacggaaggt tacaggggta ataaggcctc caccgaacat gtaattattt
    10981 ttagcaccat tattcacgat agcgtccatc atgatggtaa ggaaatccat gaaggtaacg
    11041 tcgacaattg gacgtagtcc tgtaatagct gcaccaatag ccgcaccaga gatagcagct
    11101 tctgaaattg gggtatcttt aacacgttta gggccaaatt cttcaatcat tccaacagaa
    11161 gtcccaaagt ctcctccgta aacccctacg tcttctccca taaggaaaat gttttcgtcc
    11221 ttgcgcattt cctcagtcat agcaaggttg actgcttcac gcaaagccat taattttgtt
    11281 tctgacatca tttttatttc tccatttatt attcaaatac gattgcttct tactgacaag
    11341 gtgctcttag tcaacccaaa cgtcttcgaa ggctactgaa agttctggat ctggactgtt
    11401 ttgtgcaaat tcataagcat cgtcaacttc ttttttgact tgtgcttgaa tagcatccaa
    11461 ttcgtcatca gtggcaatgc cttcgcttgt cagataagta cgatatttga tcattggatc
    11521 tttttctttc cactcatcca cttcttcttt agtacggtat ttaccagcat ctgcagtcga
    11581 gtgaccaaac caacggtatg attctacctc aacaatagct ggaccatttc caccacgaac
    11641 atgttcaacg gctttgccca ttgtttcata gacagccatc acgtcattgc catcttcaca
    11701 gtagaaacca ggaactccgt aagcttctgc acgtgtgtat aagtgtggtg tatttgttgc
    11761 attattgatg ctcattgaaa ttccataacg gttgttgatg atgaagaaaa taacaggaag
    11821 tttccatgtt gcagccatat taacagactc gtggaatgat ccttcgttag tagcgccatc
    11881 acctgagaaa gcaacagcta tattgttagt tcctttgtat tgttgagtga gggcagcacc
    11941 aactgcaaga gcgtaaccac caccaacgat accattagta ccatagtttc ctttttcaaa
    12001 atcagccaag tgcattgagc caccacgccc tttagacaca ccagttgctt taccagcaag
    12061 ctcagccatc attttattaa ggtccatgtc tttagcgatt gattgtccat gtccacggtg
    12121 atttgaaaaa ataatgtcat cgtaagacaa gtgagccacc gctccaacat tggctgcttc
    12181 ttcaccaact gagaagtgag tcatcccttg tacaaatcca cgacggacga gtttattaat
    12241 acgtgaatca aattcacgaa tacgttccat tttaaggaac atatctaaat gttgttcttt
    12301 agaaactgtt accatttcgg cctccatatt atcatattac ctttttatga taaaactttt
    12361 tttcacaatt tgcaaataat taaatcgctt tctaccttac cttatttggt tttttagaaa
    12421 tgcaatagtt tgtgaaatta caaacaaaac tgtactaaaa aatttaaaaa tactatataa
    12481 cagtttcacg ttttaccgac cttgacataa aaaacacatc attttaaaac ctctttcaca
    12541 ccttcaaaca agtagcaaag cgataaaaat aagcttagca aaactgctaa agcttatttt
    12601 tatgattcta tttgttcagc gatggtttcc cattcttcca taagagcttc ttgttcttga
    12661 tccaattggt cccattcctt ttgccaagcg attaactgcg ccgtatcatt ggaggcatgc
    12721 atgtcttctt gaatagcacc aatacgctct tcaatggttt caagtcttgc ttcaatctcc
    12781 tcatatcggc gggtcaagcg acgacgctct ttttgattag ctttttgtag ctgataatca
    12841 gtggcagagg cttcttttgt ttcctcaact gtctctcctg ctgctaggcg ggctaattct
    12901 tctagctctg cctttttctc aaggtaataa tcatagtcac ctaagtaaag ggttgagcca
    12961 ttttcggtaa tttccaaaac cttagttgcc aaacgattaa tgaaatagcg gtcgtggctg
    13021 acaaaaagca aggtaccgtc aaagtcaatg agggcattct ctagcacttc tttactgtca
    13081 atgtctaggt ggttagtcgg ctcgtccaga acaagaaaat tattgttttc catagataac
    13141 ttcgcaagaa gcagacgggc tttttctcca cctgacagca tagccaccga ttttttgaca
    13201 tcatctccag aaaagagaaa agcccctaat cggtttctga tatcgacttc tggcgtagtt
    13261 gaaaaatcct gccataattc ttccaaaact gtgttgctag acgtcaaatg tgattgggtt
    13321 tggtcataat aacctgtttc gacattggca ccatacttga gttgtccttt gagcaaaggc
    13381 aattgtccaa taatcgactt gatcaaggtt gatttaccaa taccatttgg ccctacaacg
    13441 gcaatagcat ccaacttatt gatatctaca ttaataggtt cggacaagac ttggtctcca
    13501 taaccgatgg ctgcttcctc aactcttagc acaacatttc ctgatggttt ttctgcatga
    13561 aatgtcatat gagcagattt acgcccacct gtgggtttgt ccaaacgctc tattttttcc
    13621 aattgcttac gcctagcctg agcccttttt gtggtagagg ccctgacaat gtttttttga
    13681 acaaaatctt ctagcttggc aatttctttt tgttgtttat cgaactgttt ttcttcggct
    13741 actagttttt cagcttttaa ggccataaaa cgagaatagt taccactata ccgatctaag
    13801 ccgttaggcg tcaaatctaa agtcacggtc gccactttgt ccagaaaata acggtcgtga
    13861 ctcacaatga ttagagctcc ttgatagttg gccaagtagt tctctaacca ggcaatggtt
    13921 tcaatatcta agtggtttgt tggctcatca aggaccaata gttctggctt ttctaaaagc
    13981 attttagcca aggccagacg agtattttga ccccctgaca gctcagcgat agtcatctgc
    14041 cacatgctct catcaaactt aaacccattt aaaatggctt tgatgtcaga ttcatacgta
    14101 aagccgcctt gctgacgaaa atgctctgta agcagatcat aatctgtcat cagtcgggtt
    14161 aaaacttgac ctgaaacggt tgccatatcc atttccatct gacgcaggcg cttttcatct
    14221 tggcgtaatg cttcgaaaac cttgagcatt tcctcatata ttgtttgatc tgattcaaaa
    14281 cggctatttt gagccagata agacaaggtt aggtcttttt tagtattaac ttctccgctc
    14341 gttggggttt cttccccaac caataatttt agtaaagtcg acttgccagc tccattagga
    14401 ccaaccaagg caatgcggtc acgttcatca acttgtagtg atatgttttg aaaaagaaca
    14461 tctcctgaga aagagcgttc taacttgttt ccttgtaaaa taatcatact ttcattctaa
    14521 caaaaaaata cccttttgag gacattttca gcctagtttc caaaagaaat cgaactcttt
    14581 ttaagtcgtt gattaccttc tttagcgcta acaaggaaag tggaatgact attaccactc
    14641 ccatgacgcg tctttgcaga tggcttttgt gttaagatat caaaaatttg caccacttgc
    14701 tcagtaacta tcgagatctt attggctaaa acggaatcac tgtgattaga atagtacatc
    14761 agccctataa taataatcgt tactaataag atagtttgta aaaacccttt gataaggtgc
    14821 caaaacattt tcactattag cttaggcagc cacaaaatga tcgccagtaa ttgtttcatt
    14881 tgtcacctca tgttgtacta ggaaatggtt aagacaacct ttcttctttt tggtagttta
    14941 tcggtaacca ctctaacagg acttctaatt gctggttcca atagtaccac tcatgtttac
    15001 catgaccttt atgataatca atgtcaagac cttgagcctg aaaatcagca atagcttttt
    15061 cattagtggc aaaaagaaaa tcctcatagc cacaccaagc ataaaatttg gtttttccat
    15121 cactttctgc caccatattt ttaaggtaat gcttgtcaag gtcagggtca tcaaactggc
    15181 caaaaacgcc ctgccaatag gctaattctc ccagttttcc ctcaagcaag gtctcaggag
    15241 aaaaatccaa agcgcctgaa aacgatgccg cataagaaaa ccgattgctt ttgagtgccc
    15301 acttaaaggc accatagcca cccatagaga gcccagcaac aaaggttttt tctcgtttct
    15361 gggtcatatt aggaaagaaa gctgctaaga cctgcggtaa ctcttgtgac aacgcccgat
    15421 aatagttaag tccataagcc gtgtctgtat accaacctag gtctgtcgaa ggcataacga
    15481 ctatcaaatt ggtatgccgc aacaagcgtt caatagctgt tcgtttttgc caagagtttt
    15541 cattgcctcc cataccatgt aacaaatata aaacaggaat atccttatcc ccttgatctt
    15601 ttttagggat ttcagactgg tcaggataaa tcacatttac cttacgctcc attcctaaaa
    15661 ctaccgaatg gtattcaatt gcaatacttg ccattcatta cactccttta taccaaaata
    15721 atcctatcac gtaaatctac tgtatttttg ggtgaacagt ttcctggttt accagttgtt
    15781 aaaatcaaag aaggtaggca gtttttgcct aaccttccta ttttcactaa cgaacttcca
    15841 tcacaaccgg cagaatcgct gggcgccttt tggtttgttc aaataagaat ttagacaaat
    15901 catctctgac attccctttt aattcgcccc agtcaaaggt atcttttttt aagtaattgc
    15961 caacagttgt attaactaat tctgcacttt ctcttaaaat atcatgactt ttcttgacat
    16021 acacaaatcc acgcgtatta actttagcct tagaaataat gcgtttttct tttttagaaa
    16081 cagtaatagc aacaatgaaa ataccatctt ctgacaagac tttacggtct cgtaaaacga
    16141 tattacccac atcaccgata gcattaccgt caatcatgac atcactggca ggtacacctc
    16201 cttcatggag aaaaccttcg tcattaagca ccatgatatc gccacgcttc agaatatgaa
    16261 tattctctgg aaaaatacca acttcttcag ctagctttgc atgggcagct aaatcacgat
    16321 attctccttg tactggaaaa agatactggg gttttaacaa attcatcaat agttgcaaat
    16381 cacgcccatt agcatggcct gaaacacgta agttttgagt gattaattta acagaaccac
    16441 cggccttgta aatcaagttt tcaacacgcg ccaccatagc ttctttagcc gtacttggtg
    16501 ttgttacaat ataaacaagg tctccttctt tgatttgaac ataacggtga cgtcccgctg
    16561 ccattttttg taagctatta attggctcac ccatacgacc agcttcaagg atgattaatt
    16621 catggtcttc gaatttagac atatccttag gtttaattaa aagacgctca tccgtaatca
    16681 ttaatttttc tagacgtaaa gctgttctga caatattttc tgcatctgtt ccggttaaaa
    16741 caacacgacg cccatgggca gtggcggaat caaatacttg ctgaatccga acaagatttg
    16801 aggctactgc agctacaatg acacggccat cagcatcaga gataacactg tccatttctt
    16861 caccaacttc agattcgctg gcaatctgat cgttgcttgt cgcattgact gaatctgata
    16921 aaagagctag aaccccttct ttcccaatct cagctaaacg tagcaaatcc gtctgataac
    16981 cttctcttgc tgcttgatca aatttgaagt caccggtata aataatgttt cctttatctg
    17041 ttccaataac aatacccata ctttctggga ttgaatgcgt tgttctaaag aacgaaacta
    17101 ggccatcttt aaattcaatt tcagtatcac tgtctaccac atgaaaatta ttaaatttct
    17161 tagtgctgtt attacttttc acaaatagct tggctaattc aatagtcaat tcagatccaa
    17221 atacaggagc tgatacttca gctaacaaat aaggaagggc tccaatggcg tcagcatggc
    17281 catgactcaa gaaaatccct tgtactttac ctttgttttc aattacataa tctaaattgg
    17341 ggatgactaa atctacccca agttgctcat tttcagggta cttgagccct gcgtctaaaa
    17401 taaacataga atcgttaatt tctaccaaat agaagttttt tccgtattca cggacccctc
    17461 ccaaggcaat cattttaata tcagtcatga tactccttta aatattttat tattacaaac
    17521 ggtccttaca acgtaagtcg aattactgtt atgtagcta
//
LOCUS       DAUGQX010000039        15682 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUGQX010000039 DAUGQX010000000
VERSION     DAUGQX010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15682
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.039"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            75..728
                     /gene="grab"
                     /locus_tag="VIA51_001350"
     CDS             75..728
                     /gene="grab"
                     /locus_tag="VIA51_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G-related alpha2-macroglobulin-binding protein
                     GRAB"
                     /protein_id="HEQ8683290.1"
                     /translation="MGKEIKVKCFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALADQT
                     DALQSEEAAVVKADNAASDALEALADQTDALQSEEAEVVQSDNAASDAWEKAATPIAL
                     DVKKTKDTKPVVKKEERQNVNTLPTTGEESNPFFTAAALAIMVSTGVLVVSSKCKEN"
     gene            966..1508
                     /locus_tag="VIA51_001351"
     CDS             966..1508
                     /locus_tag="VIA51_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8683291.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1517..2800
                     /locus_tag="VIA51_001352"
     CDS             1517..2800
                     /locus_tag="VIA51_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8683292.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2816..3676
                     /locus_tag="VIA51_001353"
     CDS             2816..3676
                     /locus_tag="VIA51_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEQ8683293.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3678..4643
                     /locus_tag="VIA51_001354"
     CDS             3678..4643
                     /locus_tag="VIA51_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEQ8683294.1"
                     /translation="MAEKKWFDKVLSEWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSIF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4754..6037
                     /gene="aroA"
                     /locus_tag="VIA51_001355"
     CDS             4754..6037
                     /gene="aroA"
                     /locus_tag="VIA51_001355"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEQ8683295.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLNAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSNMKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6030..6521
                     /locus_tag="VIA51_001356"
     CDS             6030..6521
                     /locus_tag="VIA51_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ8683296.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSIIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6729..8180
                     /locus_tag="VIA51_001357"
     CDS             6729..8180
                     /locus_tag="VIA51_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8683297.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILILGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8229..9617
                     /gene="rlmD"
                     /locus_tag="VIA51_001358"
     CDS             8229..9617
                     /gene="rlmD"
                     /locus_tag="VIA51_001358"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8683298.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSSARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQT
                     HHVECVVLLIKE"
     gene            9656..10434
                     /locus_tag="VIA51_001359"
                     /pseudo
     CDS             9656..10434
                     /locus_tag="VIA51_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            10519..10920
                     /locus_tag="VIA51_001360"
     CDS             10519..10920
                     /locus_tag="VIA51_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEQ8683299.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(11027..12511)
                     /locus_tag="VIA51_001361"
     CDS             complement(11027..12511)
                     /locus_tag="VIA51_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEQ8683300.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNNYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            12885..14105
                     /locus_tag="VIA51_001362"
     CDS             12885..14105
                     /locus_tag="VIA51_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8683301.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLYFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            complement(14225..14590)
                     /locus_tag="VIA51_001363"
     CDS             complement(14225..14590)
                     /locus_tag="VIA51_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEQ8683302.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            14705..15436
                     /locus_tag="VIA51_001364"
     CDS             14705..15436
                     /locus_tag="VIA51_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8683303.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKEVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
     gene            complement(15485..>15682)
                     /locus_tag="VIA51_001365"
     CDS             complement(15485..>15682)
                     /locus_tag="VIA51_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEQ8683304.1"
                     /translation="PDNGMMDSFFGILKSEMFYGLETTYQSLDKLEEAITDYIFYYNN
                     KRIKAKLKGLSPVQYRTKSFQ"
BASE COUNT         4871 a         2718 c         3328 g         4765 t
ORIGIN      
        1 aattattaat tataatttcc aaattatcgg taatttaata tgctaatgca tataaaaata
       61 aaaaaggaga aacaatggga aaagaaataa aagtgaaatg ctttttgcgt agatcagctt
      121 ttggattagt tgcggtgtca gcatcagtat tagtcggttc aacagtatct gctgttgact
      181 cacctatcga acagcctcga attattccaa atggcggaac cttaactaat cttcttggca
      241 atgctccaga aaaactggca ttacgtaatg aagaaagagc cattgatgaa ttaaaaaaac
      301 aagctattga ggataaagaa gctacgacag ctatagaagc agcaagttca gatgccttag
      361 aagcattagc ggatcaaaca gacgctttac aatcagaaga agctgcggtt gttaaagcgg
      421 ataacgctgc tagtgacgcc ttagaagcat tggcggatca aacagacgct ttacaatcag
      481 aagaagctga agtagttcaa tcagataacg ctgctagtga cgcctgggaa aaagcagcaa
      541 ctccaatcgc tttagatgtt aagaaaacta aagatacaaa acctgtagtt aaaaaagaag
      601 aaagacaaaa cgttaatacc cttcctacaa ctggtgaaga gtctaaccca ttctttacag
      661 ctgctgcgct tgcaataatg gtaagtacag gtgtgttagt tgtaagttca aagtgcaaag
      721 aaaattagtt gctatttgtt ctagcaaatg aaacaaggga atcgaaagat tctctttttc
      781 tgatatttaa aaatgctaca gtttataata gcttgaaaga ctaaatgttc tcaaactcat
      841 tagaacaagc tttaataaaa ctaacccagt tgtatcaaag gatagataaa gactaagact
      901 gttatagaat atttgcaaaa gatttgttat aatggaccca atacaggtat tgtgaaaggt
      961 ataatatgga tatttggaca aagcttgcag tgtttgcttt ttttgagact ccgaaagtaa
     1021 tattacggcc ttttcgctat gaagatcatt gggattttta cagcatggtt aacgacacta
     1081 aaaaccttta ttatgttttt ccagaacaaa aaactaaggc agcaagtgac tatcttttag
     1141 tacatagttt tataaagttt cctttaggtc agtgggcaat agaagataaa gcaacccacc
     1201 aagtaatagg ttctattaga attgagcatt atgatgctaa aacgcgttgt gctgatattg
     1261 gctatttttt aaactatgcc ttttggggac aaggaattat gacagaagtc gtaataaaac
     1321 ttgtttattt atcttttcac gaatttggtc tcaaaacgtt gcgtattata actcatttag
     1381 aaaataaggc cagccagaaa gtagctaaaa aagcaggttt tcaactaaaa acctgtttta
     1441 aaggaagtga tcgtaatact cataaaatct gcatttataa aatgtaccaa ctaactaatg
     1501 ataggtgata atcattatga gcaaacatca agatatttta gattatttag aaaaacttgc
     1561 tattggtaaa aaagtgagtg ttagaagcat ttcaaaccac ttaaaagtaa gcgatggaac
     1621 agcctaccgt gctattaaag aggcagaaaa tcgaggtatt gtcgaaacca aaccaagaag
     1681 tggaactgtt cgtattgaaa aaaaaggacg ggttcgtatt gaccgtctga cctattccga
     1741 aattgctcgg atcagtgatt cggaagtgct agcgggacat gctggtttag gacatgaatt
     1801 tagtaggttt tcaattggtg ctatgactca acaaaatatt cgtcgttact tggtcaaagg
     1861 agggttatta atagttgggg atcgtgaaac gattcaactc ttagctcttg aaaaccataa
     1921 tgccattttg gtgacgggcg gatttccagt atccaaacgt gttattgaaa tggcaaataa
     1981 ccaacgaatc ccagttatgg taactcatta tgataccttt actgtggcaa caatgattaa
     2041 tcacgcgcta tctaatattc gtattaaaac agatctcaaa acagttgaac aggtaatgat
     2101 acctattaca gattatggtt acctttgcga agacagctct gttgaagaat tcaatacatt
     2161 aataaaaaaa acacgacaag tcaggtttcc tgtattagat tataaaagaa aagtgattgg
     2221 tgtagttagt atgcgtgatg tggtggatca gttgccaaca actaagctta ccaaggtcat
     2281 gtctaaaaat ccaataacgg ctagaccaaa tactagtctt gctaatatta gccagaaaat
     2341 gatctttgaa gatttaaaca tgttacctgt cactgacgaa gaaaacaatt tacttggtat
     2401 gattactcgt agacaagcaa tggaaaattt gccaaatcac caaccaaata acccctatac
     2461 ttatagtgag caaatacttt ctaaccttga agaaacggtt gattattatc aagtagtagt
     2521 tgagccaaca atgattgata gtgctggtaa catgtcaaac ggtgttattt cagagttctt
     2581 aaaggaaatt agtatcagag ccctcacgaa aaagcaccaa aaaaatatca ttatcgaaca
     2641 aatgatggta tactttttac atgctattca aattgaggat gaattaaaaa tatatcctaa
     2701 aatcattact gaaaatagac gaagcagcac cattgatatt gaaatttttg tggatgatca
     2761 agtgattgct aaagctatta ttacaacgaa aataaattag aggagtaaca aaacaatgat
     2821 aacattaaaa tcagcccgtg aaatagaagc gatggataga gcaggagact tcttagcagg
     2881 tatccatatt ggcttaaggg atattattaa gcctggtgtg gatatgtggg aagtggaagc
     2941 atatgttcgt cgccgttgta aagaagacaa cgttcttcct ttgcaaatag gggttgatgg
     3001 tcacatgatg gactatcctt atgcgacctg ttgtggtcta aatgacgaag tagcacatgc
     3061 ctttccccgt cattacattc tgaaagaagg ggatttgctt aaagttgaca tggtactcag
     3121 tgagcctttg gataaatcaa ttgttgatgt agcagcttta gattttgata acgtacctga
     3181 gatgaagaaa tggacaggat cttataccgg tggtttagct gactcttgtt gggcttatgc
     3241 tgttggaaca ccgtctgacg aaataaagca attaatggat gtcaccaaag aagccatgta
     3301 ccgtggtatt gaaaaagcag taattggcaa tcgtattggt gatattggcg cagctgttca
     3361 agaatacgct gaaagcttcg gttatggtgt cgtgcgtgat cttgttggtc acggtgttgg
     3421 tcctacaatg catgaagagc caatggtacc aaactatgga acagcaggtc gtggacttcg
     3481 tctaaaagaa ggcatggtct tgactgttga gccaatgatt aatacaggaa cttgggaaat
     3541 tgataccgac atcaagacag gttgggctca taaaacccta gatggtggtt tatcttgcca
     3601 atacgaacac caatttgtga ttactaaaga tggtcccgtt attttaacaa gtcaaggaga
     3661 agaaagaact tactaaaatg gcagaaaaaa aatggtttga taaggtactg tccgagtggc
     3721 agtatgaacc cattcaagtc tttatgaggc atttacaaag tgcagaaatg gatttatctg
     3781 ccattgcggt tgcgtattac cttatcttaa cggcctttcc attaattgtt attgcagcca
     3841 atatttttcc ttacctcaat attgatattg ctgatttgtt acgtttaatg aagcaaaatt
     3901 tgcctaaaga tatttttaga ccggcttctg caattgtaga aaatattttc tctaaaccgt
     3961 ctggaagtgt tttgggagta gcgactttga caggattatg gacaatgtct cgaagtttga
     4021 catcgctaca aaaagctatt aataaagcct atggcgcttc tcagcatcga gatttcttta
     4081 tcggacactt ggttggtttg ttgaccagtt taattatttt atttttatta gcctttgcct
     4141 taatcttttc aatattttct aaagctgcta ttcaagtgct ggataagcat taccatttga
     4201 gtgataatat cacaacgatt ttcttgctcc tcattcaacc tattacagtt ttgattattt
     4261 ttgttggctt gatgctacta tattttttat tacccaatgt taagattaaa aaaattcgct
     4321 acattttacc aggaacccta tttacatctt ttgtgatgac atttttgagt aatctggttg
     4381 gcaattacgt tgtgtataat gttgagcgga tggtagatat taaaatgttt ggttcagtta
     4441 tgatttttat catcatgcta tggtttattt tcttagcaag aatcctgatt ttaggagcta
     4501 tatttaatgc gacctatcaa gaaatgtcct tggggaaatt agaaggtcgt agtggtgata
     4561 tgatcgctat ccttaaaaaa acacttggga atgattcaga tctatctcct tcacagtcta
     4621 tcgaagatag tcacactgat tgatacaaaa aagataataa gtcgtggagt gagaaactat
     4681 tttcttgctt cattttttat gaggatgaat agaaaatcat tgatcttagc aaatagaaag
     4741 gcagatgaaa cggatgaaat tgcgaacaaa tgcaggacca ttacagggaa cgattcaagt
     4801 tccaggagac aagtccatta gtcaccgggc agtcatatta ggagccgttg ctaaagggga
     4861 aacacgagta aaaggactct taaaaggaga agatgtgctt tccacgattc aagcctttag
     4921 gaatttgggg gtccgtatcg aagaaaaaga tgaccagctt gtgatagaag gtcaaggttt
     4981 tcaaggattg aacgctcctt gtcagacact taatatggga aattctggaa cctctatgcg
     5041 cctcattgct ggcttattgg caggtcaacc ttttagtgtc aaaatgattg gcgatgaaag
     5101 cttatccaaa cgtcctatgg atcggattgt ttatccgtta aagcaaatgg gggttgagat
     5161 atctggagaa acagataggc aatttcctcc actacaattg caaggtaatc gtaatttaca
     5221 accaatcaca tataccttgc ctatctcttc tgctcaggtt aagtcagcta ttttattagc
     5281 agctttgcaa gcaaaaggaa caacacaggt tgttgaaaaa gagattactc gaaaccatac
     5341 agaagaaatg attcaacaat ttggtggacg attgatagtt gatggtaaac gcattacttt
     5401 ggtgggaccc cagcagctca ctgctcaaga gataactgtc cccggagata tttctagtgc
     5461 agctttttgg cttgtcgccg gcttaattat tcctggttcg gagctccttt taaagaatgt
     5521 tggagtcaat ccgacacgaa cagggattct tgaagtggtt gaaaaaatgg gagcacagat
     5581 tgtctatgaa gatatgaata agaaagagca agtaactagt attcgagtgg tatattctaa
     5641 catgaaagga actatcatat caggaggtct tatccctcga ttgattgatg aactgcccat
     5701 cattgcactt cttgcaaccc aagcacaagg aacaacctgt attaaagatg ctcaagaatt
     5761 acgagtcaaa gaaacagatc gtattcaagt agtaactgat attcttaaca gtatgggagc
     5821 taatatcaaa gcgacagcag atggcatgat tatcaaaggc cctacggtac tatatggggc
     5881 taacacaagt acctatggag atcatcgtat tggtatgatg acagcaattg cagccttgct
     5941 tgttaaacaa ggacaggtcc atttggataa agaagaagcc atcatgacgt cttatccaac
     6001 gtttttcaaa gatttagaaa ggctgtgtca tgactaaagt gttattggga tttatgggag
     6061 tggggaaaac aacggtttcg aaacacctaa gtatgcactg taaagatatg gatgctatta
     6121 ttgaagctaa aatcggtatg tctattgcag ctttttttga acagcatgga gaaatagcat
     6181 ttcgaacaat tgaaagtcaa gtgttaaaag atctattgtt tgcaaatgat aatagtatca
     6241 tcgtaacagg tggcggtgta gtggttttac aagaaaatcg acaattactg agaaaaaatc
     6301 accagcataa tattttattg gtagcttctt ttgaaacttt gtaccagcgt ttaaaacatg
     6361 ataaaaagtc tcaaagacct ctatttctta agtactctaa ggaagcattt tatgaatttt
     6421 atcaacaacg tatggtattt tatgagggac tttcagattt agtaatcaga gttgaccatc
     6481 gtacgcctga agaagttgcc aacatcattg agggttatta gtaggtcatt gtcgtaatct
     6541 gatatttatg gttttaaaca ggtatctgtc taaagcactt cttatggcaa gttggcttta
     6601 ttaaatatta ggaaataatc ttgattattc tataatgatt aaaattttga gaggacaatc
     6661 tggctaatat aggttataat ggtagtattc gttaaaagtg caattgtaat actaagagat
     6721 gataagatat gacaaaatac cccatgggtg gccttagtca ccatgaagaa ttacgttatt
     6781 tttatctcct aaggaatttg agttacctta gtgagaatga aaaaaaagag tttgcttttt
     6841 taaaatctaa attggaaatt ggtcgagctt atgctccttc taagcagcat tataggaagt
     6901 caaaacggca agaaccttac tttgaagatg actactataa cgactactca ccaaatgatt
     6961 tactagaaga tgatgacgtc aatcatgact cttcttttgt tccatatggt ttaccgatat
     7021 atcctaaaga agacagatat ttaaacaaaa aaacaaaact tacagctcgt agacctatag
     7081 atgctccgca gcctattgat gaagacgatg cttttttaac agagtctgtt gctcgttgtg
     7141 ctcttcctag atctcaaaaa aggaagcata agaaaaaagg atgtatgaaa tggtttttta
     7201 acattcttgg cttattgcta atgactgtgc ttatggggtt agggttgatg tttgcaaaag
     7261 gggtttttga tatttctact aataaagcta attacaaacc agctgtttcc caagcttttg
     7321 atggtcaaga aactcaagat ggtacgaaca ttctgatttt gggttctgac caacgagtta
     7381 ctcaaggttc tacagatgct cgcacagata ccattatggt tgtcaatgtc ggcaaccatg
     7441 ctaaaaaaat aaaaatggtc tcttttatgc gtgacacttt gattaacatt ccaggataca
     7501 gttataatga taattcgtat gatcttaaat taaatagtgc atttaatctt ggagagcaag
     7561 aagatcacca cggagcagag tacgttcgac gggccttaaa acataatttt gatatcgaca
     7621 ttaagtatta tgtgatggta gattttgaaa catttgcaga agctattgac accttgtttc
     7681 caaatggtgt taagattgat gccaaatttg cgacagtagg tggtgtagct gttgactccg
     7741 tagaagttcc agatgacttg cgaatgaaaa atggggttgt tcccaaccaa accatcgaag
     7801 ttggagaaca acgcatggat ggtagaacct tgctcaacta tgctcgtttc cgtaaagatg
     7861 acgaaggaga tttcggacga accgtccggc agcaacaggt tatgtcagct gttatgtccc
     7921 aaatcaaaga cccaactaaa ctctttacag ggtctgcggc tattggtaaa atctatgcgc
     7981 tgacttcgac caatgtttct ttcccatttg ttgttaaaaa tggtgtttct gttttaggaa
     8041 gtgggaaaaa tggagttgag cacgtgacca tcccagaaaa tggggattgg gttgacgaat
     8101 acgatatgta tggaggacaa gccctttaca tagattttga taagtatcag aaaacgttag
     8161 ccaaattagg tctgcgctaa gatatggtat aatggagagt aactaaagtt gctcttcttt
     8221 tttgagcaat ggttagccct agaaaaggaa aaagaataag aatgttgaaa aaaaatgata
     8281 ttatccaagt tgctatttca gatttaagcc atgagggagc aggtgtcgct aaacacgatg
     8341 gttttgtttt ctttgttgat aatgccttgc cagaagaagt gattgacatg cgtgtcttaa
     8401 aggtcaataa aaacagcggt tttggcaaag tagaagccta tcattacctg tcgtcagcta
     8461 gaaatgcaga tgtcaattta acttatttgc gaacaggcat tgcagacctt ggacatctaa
     8521 cttatgaaga ccaactgact ttcaaaaaga aacaagttca ggacagcctc tataaaattg
     8581 ctggaatcag tgacgtgaca gtcgaaagca cgattgggat gacagaacct ttagcttacc
     8641 gaaataaggc tcaagttcct gttagacgtg ttaatggtca gctagaaaca ggctttttcc
     8701 gcaagcattc tcatgacttg attcctattt cggattatta tattcaggac aaagagattg
     8761 atcgtctcat taattttacc cgtgatttat tacgccgctt tgatattaaa ccgtatgacg
     8821 aaacagaaca aacaggtctc ttgagaaata ttgttgttcg ccgaggtcat tactctggag
     8881 aaatgatgct ggtcttagtg actacacgcc caaaagtttt ccgtgttgac caagtcattg
     8941 aaaaaatcgt tgaagctttt ccagcagtgg tgtctattat tcaaaatatt aatgataaga
     9001 acaccaatgc aatctttggt aaagatttca aaacgcttta cggcaaggat accattactg
     9061 atagcatgct tggaaacaac tatgccattt ctgctcagtc tttctaccaa gtgaatacgg
     9121 ttatggcaga aaaactctat caaacagcta tagccttttc agacctttct aaagatgata
     9181 ttgtgattga cgcctactca ggtatcggaa ccattggcct atcatttgct aaaaccgtta
     9241 aagctgttta tggtgttgaa gtgattgaag cagctgttag agatgctcaa cagaatgccg
     9301 ctcttaatgg catcaccaat gcctactttg tcgcagatac cgcagaacat gccatggcaa
     9361 catgggcgaa agatggcatc aaaccaagtg ttattctggt agacccgcca cgaaaaggct
     9421 taacagaaag tttcatccaa gccagcgtgg caatgggacc acaaaaaatt acctacgttt
     9481 cctgcaaccc agccaccatg gcgcgtgaca taaagcgtta tcaagagttg ggttacaaac
     9541 tggccaaagt acagcccgta gatttgtttc cgcaaacgca tcacgtcgag tgcgtagtgt
     9601 tgctaatcaa ggagtaaggt agctgcctcc acatgacaaa aataaggaga aacgaatgcc
     9661 tattaccaaa cacgagattc cccttttaga atgtgatagt aatccatcag ccgtcattat
     9721 ctagctattt agcttccagc taagtgtgtc tatgctttct tagaagacga gattgaagct
     9781 tttgctttag accatcaagg taaaaaagta gcagaattca tttcagccac aaaggtttac
     9841 cctgtttatc agatatctta taaaggccaa gacatttgcc tagctcaagc tcccgttggc
     9901 tcagctcctg cggcgcaatt catggactgg ctgattggtt atggggttaa agaaatgatc
     9961 agtacaggaa cctgtggcgt tttggttcct atcgcagaaa accgtttttt agtgccagtt
    10021 aaggctttgc gagatgaagg aacaagttat cattacgtgg caccatctcg ttatattgat
    10081 attgatccta agatgcttag actgattgag aaaacgcttt tagcacaggg gttagcttat
    10141 caagaggtca tcacctggtc aacagatggt ttttaccgag aaaccaaaga aaaagtggct
    10201 tatcgccagg aagaagggtg ttcggttgtt gagatggaat gttctgcctt agcagcagta
    10261 gctcaattaa gaggcatcct ttgggggcaa ctcttattta cagcagatac tctagcagat
    10321 gtagaggttt acgatcaacg caactggggc gctgattcct ttagttttgc gctccattta
    10381 tgcttggaag tgctcaatac gctagaaaag gatggaaagg ctactgattt ttgaaacatg
    10441 agctctgcct tctgttccta tttgtagtat aatgaggctt gtattgcttt tagactaagc
    10501 ttagaaaaga gaaaaacaat gtcagattta acacaagaga tgaccttaaa tgttattagt
    10561 atttttgata attaccaaat tgaacttgct gaaaaaggac accttatttt aagtactgaa
    10621 gtgactgaga cggctttgaa ttattatggg aatgcccatg gtggttatct tttcactcta
    10681 tgtgatcaag taggtggttt ggttgctaga actactggcg tagaatctgt caccttacag
    10741 gccaatgcta actatttaaa agcagggcac aagggagaca agctgatggt tgaaggtcga
    10801 ttggttcatg gaggtcgaac cacgcaggtg gttgatgtga cgattcataa ccaaacagga
    10861 gctcttctaa caaaaacaag cttgaccatg tttgtgactg gccgacgtca taacgggtga
    10921 ttaatgaatc atagaaggct aaaaaagtcc caactctctg agaattggga cttttttcct
    10981 ttattgagag ataccataaa tcacccgtta gacgggtggt tatggtttat ttacggtaaa
    11041 gtttgtgatg ttggtaaaca gggtcaaagg taatatttac cccaagtttt cggagtacat
    11101 ttttatcttc ttcggttaag ataacggtag aatgggcttc gctacctttc aaattgccaa
    11161 gttctttcat ggctagatta gcttcttcac tagtcatagc agtaatggcc aacgcaatca
    11221 gaatttcatt ggaatgaagc cgcggattgt gactgcctaa gtggttcact ttgaggcctt
    11281 gaataggttt cacgtattcg ggttcaatca aatgagtggt tttatcaatc tttgccaagg
    11341 ttttaatcgc attgatgata acagctgcag ttggtccaaa gagttcagat gttttacctg
    11401 tcacaatctg cccatttggt agttggagag caagggcagg ttggcctgtt tgctctgctt
    11461 tttgatgagc agctacagta acgtgacgat cgtcaggggt gacaccgata tcattcatca
    11521 agagctcaat ttttttgaca gcagattctg tgactcgctc tgccttgaaa tccacgaggg
    11581 tttggtaata acgacggatg atttcttgtt tagaagcttc gatagcagct tcttcattga
    11641 cgatagaaaa accaaccatg ttaacaccca tatcggttgg tgaggcataa ggagacttgc
    11701 tcaaaatacg ctcgaaggtc cgatttaaga caggaaagac ctcgatatca cggttgtaat
    11761 taacggccgt tttgccataa gtttccaaat ggaaggggtc aatcatattc acatcatcta
    11821 ggtctgccgt ggctgcctca taagccagat tgacagggtg atgaagagga agattccaaa
    11881 ctgggaaggt ttcaaattta gcatagccag acttaacccc attgatttgg tcgtgataca
    11941 tttgggacat gcaagtggct aattttccag acccagggcc tggtgctgta acaacgataa
    12001 ggttacgact cgttttgatg taattatttt tccccatccc ctcagatgag ataatatgat
    12061 taatatctgt cgggtagccc ttgataggat aatgcaggta agaagcaatg ccattttttt
    12121 cgagttgctt gcgaaaggca tctgcagcgg gttggttatt gtattgagta ataacgacag
    12181 aacctacgta aatatctaac gtgttaaatt tgtcaattaa gcgaaagact tcttggtcat
    12241 aagaaatgcc taaatcacca cgcgctttag aatgttcaat attattagcg ttaatggcaa
    12301 ttacaatttc gacttgttct ttgagctctt tgagtaattt aatcttattg tcaggttcat
    12361 agccaggaag cacacgggca gcatggtaat cttctaacat tttaccacca aattccatgt
    12421 aaagcttgcc atcaaattgg ctgatacgtt ctaaaatatg atctctttgc aagtttaaat
    12481 acttgttaga atcaaaagca atagtcttca ttttttcacc tctgtaaagc attataacaa
    12541 agaaattcca agaaagaaaa ggttttttgc agggatacct cattttgtga ctttttaaaa
    12601 aaacttaggc ttggttctta gaagaaaaat gtatccgcta tgttcaaaag aacttgacaa
    12661 ttaaaatgag ctttactata ctagtaacaa ttaaatacta ctttaaacat gttccgtgaa
    12721 gcatgaaagt cttaacagta aagagagttt ttttgtcatc tcttattatt tagtgaactt
    12781 tgatggactt gcggacttgt ttccaagtct ttttttgacc tttggacaaa gggtattcaa
    12841 ttaattaagg tagtcagtga gctactatta agaaggagac aattatgtca acattatcat
    12901 tggacaccac aaataagcga gctttagtgg cagctattgc agcttcagga acggatgact
    12961 tgaatgtcat gtttcttgcc ttttccatgt cttccattat gacagacttg ggtcttagtg
    13021 gcactcaggg tggctggatt gcgaccatta ccaatttagg aatgttggtg ggaggcctct
    13081 tattcgggtt gctggctgat aggcaccaca agtttaaggt ctttaaatgg acgattttac
    13141 tgttttcagt agcaacagga ttaatttatt ttacccagtc tttgccctac ctgtacctga
    13201 tgcgatttat tgctggcata ggagttggag gtgagtacgg tgtagccatt gccataatgg
    13261 cagggattgt accaccagaa aaaatgggtc ggatgtcttc tttaaatggt attgctggcc
    13321 agcttggctc tattagttcg gctcttttag cagggtggct ggctccaagt ctaggctggc
    13381 gtggcctttt tctctttgga ttacttccga ttctcttggt gatttggatg actttagcca
    13441 tagatgacca aaaaatttgg gatcattatg ggcaagagga ggaagaatgc agtcaaccaa
    13501 ttaaaatcaa tgaactattc aaaacaaaat ccttaacagc tcaaaccctt gctttaatgg
    13561 tcatgacgac tgtgcagatt gcgggctatt ttggaatgat gaattggttg ccaaccatta
    13621 ttcaaacaag cttaaacctt tcagtaaaaa gttcgtcttt gtggatggtg gctactattg
    13681 tcggcatgtg tttggggatg ctgtattttg gtcagctttt agattgcttt ggtccacgtc
    13741 tgatttattc cctcttttta ttagcatcat ctatttgtgt ttaccttttt caatttgcca
    13801 attccatggc gagtatggtt attggaggtg ctattgtcgg tttttttgtc aatgggatgt
    13861 ttgctggcta cggggctatg attaccagac tttatcccca tcacattcga tccacggcta
    13921 ataatgttat tttgaatgtt ggccgtgctc taggaggatt ttcgtccgtt gctattggta
    13981 gtattttaga tgcctcaggt atttcaatgg tcatgatttt cctagcttct ctgtatgtga
    14041 ttagttttgg agccatgtgg tctattggtc agttaaaagc agaacgctac caacaattgc
    14101 gttagcaaag agatgggtgt tagtatttga gttactttca ctcacaaagc tattttattg
    14161 attgagataa ccaaaaaggt aagcacttag ggattgctta cctttttggt tcttttcttt
    14221 tgttttactc cgctactttg gccataaaat gtttactgtt caccctaact ctagtatgac
    14281 aggcttttcc aatgagttgt tctcccacaa aagcttccaa gcggaaatcg tattttcggc
    14341 cttcttcttt aagggctgta atgataattg taacaggatc tccaatggct gaagctgcca
    14401 aatgttggat agctatctcg ctgccaaccg ttgtaaagtc actgtcgagc tgttcttggg
    14461 caaataagta agaagcattt tccataaaag caacaagagc aggagtagct aggacattca
    14521 gcgttcctga gcccatggct ttagccgaat gattgggacg ggtttcataa gtgtgagaat
    14581 aaatagtcat aagttaatct cctcgtttct ataagcctat tataatatat taagcgctta
    14641 cagtcatgaa actactgttt ttttatgtta tacttaataa tgaattttct ttgaaagggt
    14701 tatgatgcgc ttagataaat ttttagtggc aactggtgtt ggaactagga gccaagtcaa
    14761 acttctctta aaaaagaagg ctattttcgt caatcaaaag gttgaaacct ctgccaaagc
    14821 acacattgat gaatacaagg atttggtgac gtatcaaggc acgcccttgg tctatgaatc
    14881 ctttgtttat tacctgttaa acaagccgtc agggtatgtg tcagcaaccc aggacagaca
    14941 gcaggctact gttatggagt tgttagatga cacggctagg caaaaagcag tttttcctgt
    15001 gggtaggtta gataaggata cccgtggact tttgctcttg accaataatg gacaactagc
    15061 ccatgacctt ttatccccta aaaaacatgt tacgaaagag tacttggcta aagtagcagg
    15121 catcatgact gaagctgata aagattattt tgctagaggt atttccttaa aggatcacca
    15181 gtgcctacct gctcatttag aagtgcttgc tagtgattta cagcagcaaa caagtttggt
    15241 taaaattacc atacaagaag gaaaattcca tcaggtgaaa cgcatggtag cagcctgtgg
    15301 aaaggaagtg cttgacttac agcgtctcag catgggacca ttaaaactag accctagcct
    15361 tgcagaaggg gagtttaggc gcctgacgcc tgaggaattg cagagcctag caccttattg
    15421 tcagagctca ctataaaaag aaacctcccc ggtcagtact gaccccaaaa agttggacaa
    15481 ataattattg aaaggattta gttctgtatt ggacaggact aagtcctttt agttttgctt
    15541 taattcgttt gttgttgtag taaaaaatgt aatctgtaat agcttcttca agcttgtcaa
    15601 gtgattgata agttgtctcg agtccataaa acatttcaga tttgagaatg ccaaagaagg
    15661 aatccatcat gccgttatcc gg
//
LOCUS       DAUGQX010000040        15379 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUGQX010000040 DAUGQX010000000
VERSION     DAUGQX010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15379
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.040"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            102..350
                     /locus_tag="VIA51_001366"
     CDS             102..350
                     /locus_tag="VIA51_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8683305.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLSKTNN"
     gene            387..998
                     /gene="amaP"
                     /locus_tag="VIA51_001367"
     CDS             387..998
                     /gene="amaP"
                     /locus_tag="VIA51_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEQ8683306.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFNIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1009..1197
                     /locus_tag="VIA51_001368"
     CDS             1009..1197
                     /locus_tag="VIA51_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEQ8683307.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1210..1749
                     /locus_tag="VIA51_001369"
     CDS             1210..1749
                     /locus_tag="VIA51_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8683308.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1790..1990
                     /locus_tag="VIA51_001370"
     CDS             1790..1990
                     /locus_tag="VIA51_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8683309.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2001..2489
                     /locus_tag="VIA51_001371"
     CDS             2001..2489
                     /locus_tag="VIA51_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8683310.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2652..3293
                     /locus_tag="VIA51_001372"
     CDS             2652..3293
                     /locus_tag="VIA51_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8683311.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICNQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3436..3978)
                     /locus_tag="VIA51_001373"
     CDS             complement(3436..3978)
                     /locus_tag="VIA51_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8683312.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4096..4797
                     /locus_tag="VIA51_001374"
     CDS             4096..4797
                     /locus_tag="VIA51_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683313.1"
                     /translation="MAFIELKQVSKSYQIGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMAQTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4812..7448
                     /locus_tag="VIA51_001375"
     CDS             4812..7448
                     /locus_tag="VIA51_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8683314.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSHLRLTNAFS
                     KDYQKKVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSTLISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLILTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSDTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7540..8136
                     /locus_tag="VIA51_001376"
     CDS             7540..8136
                     /locus_tag="VIA51_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8683315.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDVADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8147..9103
                     /locus_tag="VIA51_001377"
     CDS             8147..9103
                     /locus_tag="VIA51_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8683316.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9200..10540
                     /locus_tag="VIA51_001378"
     CDS             9200..10540
                     /locus_tag="VIA51_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEQ8683317.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELKKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALVKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10656..11540
                     /gene="truB"
                     /locus_tag="VIA51_001379"
     CDS             10656..11540
                     /gene="truB"
                     /locus_tag="VIA51_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEQ8683318.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11569..12501
                     /locus_tag="VIA51_001380"
     CDS             11569..12501
                     /locus_tag="VIA51_001380"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEQ8683319.1"
                     /translation="MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12544..12948
                     /locus_tag="VIA51_001381"
     CDS             12544..12948
                     /locus_tag="VIA51_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEQ8683320.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            12950..13228
                     /locus_tag="VIA51_001382"
     CDS             12950..13228
                     /locus_tag="VIA51_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEQ8683321.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13218..14006
                     /locus_tag="VIA51_001383"
     CDS             13218..14006
                     /locus_tag="VIA51_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEQ8683322.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAITLEDQ"
     gene            14009..15319
                     /locus_tag="VIA51_001384"
     CDS             14009..15319
                     /locus_tag="VIA51_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEQ8683323.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALAMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLIKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
BASE COUNT         4955 a         2541 c         3192 g         4691 t
ORIGIN      
        1 ctttttgaaa gtcgactatt aaaagactat tgcttgaaga atgacagctg ttattcttcc
       61 ttggacaaaa ggtacaggag tatctaaaaa ggagaattat catgggactt atttggactt
      121 taatcgtcgg tgcgcttatt ggtgtgattg ctggagcact tactaaaaaa ggtggttcaa
      181 tgggctggat tgcaaacatc gctgctggtc tagttggttc ttccgttggt caagctttac
      241 ttggttcatg gggcccttct ttagcaggaa tgtctttgat cccgtcagtt attggtgccg
      301 ttatcgttgt tatgatcact tcttttgtac taagcaaaac taacaactag tttcctcttt
      361 atttagtaag tacttacaaa tagagaatgt taagtagaaa agaggtctgt atgtcaaaat
      421 tgttaaagat tagttattgt cttgtcggac ttgttctatt gtctgttttt ggatgggtag
      481 ttggaataac cggaggctat atatatttac cttatagtta tcgttggcta agttggggta
      541 tggatagttt tcccaatctc ttagattcag ctttatccta ttattacttc tggacagccc
      601 ttgtattatt tgttataaca tttcttgcct tattagttat tattttatac ccaagaattt
      661 atactgaggt ccagttacgc cataaaaata aaaaaggaac acttttatta aaaaaatcgg
      721 ctattgaaag ttatgttgcg accgctattc aaactgcagg tttgatgcca aacccaacag
      781 tcacagctaa attatataag cggaagttta acattatcgt taaaggacgt ttagcttctc
      841 gtgtagcagt ggcagatcaa attagtggcg tgaaagaagg gatcgaaaaa ggtttaaccg
      901 agttcttcgg aattaattat cctgttaatt tcaaagttta tgttaaagat attgctgatt
      961 ctgatcgtaa acatattacc agaaatcgtg tagaatagga gatctatcat ggaattttat
     1021 gaaaaattca agtaccctat tattggtggc ttggtggggc taattattgc catattgctc
     1081 atggcttttg gtttattcaa aacgctacta gcaattattt tcattatttt aggaatatat
     1141 ggtggcctgt atgccaaaaa aacaggtatt attgatcaat ttcttaatcg taaataaagg
     1201 agacttatta tgactgaaac ttatattaaa aacacatcta aagacttaac ttcagcaatt
     1261 cgtggccaat taacatatga tgataaagta attgaaaaaa ttgttggttt agcacttgaa
     1321 aatgttgatg ggttactggg tgtaaatggt ggtttttttg ctaacctaaa agataaatta
     1381 gtaaacaccg aatctgtacg tgatggcgtg aacgtggaag ttggaaaaaa acaagttgcc
     1441 gttgatcttg atattgtcgc tgaatatcaa aagcatgtgc cgactattta tgactctatt
     1501 aaatcgatcg ttgaagaaga agtgaagaga atgaccgatc tggatgtgat tgaagttaat
     1561 gttaaagtag tcgacattaa aacaaaagaa caatttgaag ctgaaaaagt aagtttacaa
     1621 gacaaagttt cagacatggc acgttcaaca tctgaattta cgagtcatca agttgagaat
     1681 gttaaagctt cagtggataa cggtgttgaa aaacttcaag atcaaaaagc tgagccacgt
     1741 gtaaaataat catatgtcgt caattaggta agctaaagga gggtttattg tgtcagatga
     1801 aaaatataat gcgaaattag atcaagctgg tggcaagtta aaagaaggat ttggtaagat
     1861 ttctggagat aaatctttag aaactgaagg taaagtagat aaagttactg gaaaagttaa
     1921 agaggttatt gcagacgcca aagatactgt aaaaggatta gctaaaggct tagataataa
     1981 agataaataa aggggacatg atggaaaaaa ctcaaattaa aagcactctt acttatgacg
     2041 ataaggtcat cgaaaaaatt gtcggtcatg ctttggaaaa cgttggcgga ttactagctg
     2101 taacaggtgg atttttctca aatatcaaaa ataatttggt gaattctgag tctgtaactg
     2161 atggtgtttc agttgaagtt ggtagcaagg aagtagcagt tgatttagca atcattgtag
     2221 aatacggtaa agatattcct gctattgcag aatctattaa agctattgtt tctcaaaacg
     2281 ttgacagtat gacacatttg aaagttgttg aagtcaatgt gaacgttgtt gatattcgta
     2341 ctaaggaaga acatgaagct gctagcgtta ctgttcaaga tcgtgtcact agtgcagctt
     2401 caagtacttc acaatttgta tcagaacaaa cagaaaaatt aaaagatact atctctgata
     2461 ctgtaaatag tgatgaggca gctaaataag caatcgtcta ggaagtatta ttgactggtg
     2521 gtgataagtt tgagctggta tttaccagct ctttttgtca cggttaaaaa gatacggact
     2581 attgtcatct ctctaaaaat atgatttaat tagatataaa tttttcaaat tattagaaag
     2641 gagtaaatta agtgataagt cctaaaaaag agataacaag ttcaaaatat caaaaaattg
     2701 ctatttcagt agctcagcgt atcgcaaatg gcgaatatga agtgggcgaa aagttaaagt
     2761 caagaactac tatcgcctcg acatttaatg tatcaccaga aacggctcgt aaaggcctga
     2821 atattttagc tgacttgaaa attttgactt taaaacatgg tagtggagct attgtgctgt
     2881 caaaagaaag agctattgag tttataaatc aatacgaatc aacccattcc atcgctgttt
     2941 taaaagaaaa aatacgtgag actattaatg atcagggaaa agcaatggaa aaaatggctg
     3001 ttttggttaa tgatttttta atgcaaagtc aatctgttag taagcaatac ccattagcac
     3061 cttatgagat tatttgtaat caagattcgg aacattttgg caaatctatt ggtgtgttaa
     3121 atatctggca ccagacagga gcaactatcg tcgctattga acatgctggt cagtttatcg
     3181 tttcaccagg tccttattct gttattgaaa aaggcgatca tatttatttc gttggtgatg
     3241 agtcagtcat ttcacgaatg aagacctttt ttaatttacg aaaaggatta taagtttgag
     3301 ggcccacctc aaactttttt tgttgctgtt gagcattatt aaaagaggca gatcatcatg
     3361 gtttgtcttt ccaaaatatc tgtttagaca gttgtttggg attgggagca tgatttcaga
     3421 ctcttttgat gttttttaat tgtctagagt aactgctttg agaataatat cggcaacctc
     3481 ttcagtggtt tcttgatagc cattagcaat ccaatagctg ataatgctct caatactggc
     3541 aaggtaaact tctaaagcat agggataagg aatatggtat tgattggtca caatgtcttg
     3601 gaaaccagta atagtagtca aaaattggta acagaaatcc ttgatgagtt gcggaaattt
     3661 gaggtaagaa atagtagcga gtgcggttat aaattctcta tgttctataa ggtaggacaa
     3721 ggtttgattg aggacttgtc gagtgtctgt gtagatttca gcctgattta acaaacggta
     3781 caaatcatcc agagtgtcat ttttgaagtg attcatcatg tcaaatttat cagtgtagtg
     3841 gaggtagaag gttcctctat tgataccagc ctttttagta aggtcagaga cagtaagagt
     3901 ttcaaaagat tgttcagtta gtaaggtggt taaggcggtc tttacataag ctttggtttc
     3961 agtatgtctt ttggtcattc tcaggtgctc cttaaatcaa cagttgcgtc agatttgttc
     4021 ttgttaaata cttagggcca ttatataata aggctataat taaatcaaca ctatgttcaa
     4081 ataatggagg ggcagatggc ttttattgaa ttaaaacagg tttcaaaatc ttatcagata
     4141 ggagagacga ctgtttttgc caaccacgaa gtgtcttttg agattaataa aggagaacta
     4201 gtggttattt tgggagcatc cggagctggt aaatcgacag tcctcaatat tttggggggc
     4261 atggacacag tagatgcagg tcaagtaatt attgatggca aagacattgc tcattacacg
     4321 tctaaggcct taactcagta tcgtcggaat gctattggtt tcgtttttca attttataat
     4381 ttggttccta atttgacagc taaagaaaat gttgaattag cagttgaaat tgtagcagat
     4441 gctttagatc ctgtgaccat tttaaaggaa gtaggactca gtcatcgtct ggatcatttt
     4501 cctgctcagc tctcaggtgg tgaacagcaa cgggtttcga tagcacgtgc cttagctaaa
     4561 aaccctaaat tgcttctttg tgatgaacct acaggtgccc ttgactacca aacaggaaag
     4621 caaattctaa ccctcttaca ggatatggca caaactaagg ggaccacggt agttattgta
     4681 acccacaatg ctgctattgc tccgatagct gatcgtgtca tttttatgca tgatgcacag
     4741 gttaccaaga cagtcattaa taaggaacct gcaagcattg agacaattga ttattaagag
     4801 gaaggtgtcg tatgataaag aaaaccttat ggaaggatat tttgagagct atcaagaata
     4861 gtaaagggcg attcatttcc ttatttttcc taatggcctt aggctccttt gctttagttg
     4921 gacttaaagt caccggtcca gatatggaac gaacagccag ccgttacctc gaaagacacc
     4981 aggtgatgga cctaacggta ctggcttctc atcaattttc ccaagccgat aaacaagagt
     5041 tagatacgtt aaaaggggct catttagaat atggtcattt acttgatgtc agtctaacta
     5101 gcaaccagaa atctcttagg ctctatagcg tgccaaagaa agtgtctaag ccagtcttgg
     5161 ttaaagggag ttggccaaag cgagagacag atttggtttt atcctcctca cttgctaaaa
     5221 actatcagat tggagatgaa ctagcagtca cctcacctat ggaaggtttg ctgacgacaa
     5281 cccattttca agtggttggt tttgcgaatt cttcagaagt ttggtccaag tccaatttag
     5341 gaagttcctc aaccggagat ggaagtctct acgcttatgc ttttgttaat ccaaacgttt
     5401 ttaaaagtgc ctttaacctg ctgcgcatcc gttttagtca tcttcgtctg acaaacgctt
     5461 tttccaaaga ctatcaaaaa aaggtaaccc aaaaccaagc tcatttggat aatctactta
     5521 aagataatgg ccagaagcgt tatgatgacc tccaaaatca gtatgacctt gccttaaaaa
     5581 atggcagagc agcacttgca aaggaaacag tgaaactagc tgcgagtgag gagaacttaa
     5641 cttttttaga aggctctgct ttacaagaag ctaagcatca gattgaacaa ggcaaacaag
     5701 cattagccaa ggaggaaaag cagttagagc aggtgcaggc tacaaaagat aagctagaaa
     5761 aacccagtta cctgacttat aatcgctcga ccctaccagg aggagaagga tatcatactt
     5821 atgcaacttc aacgacctcc atttcaaatg ttggaaatat ttttcctgtt gttctttatc
     5881 tcgtagctgc tctagtagcc tttaccacca tgacacgtta tgttgatgaa gaaagaacaa
     5941 gctctggtct attaaaagcc attggttatt ctaacaagga tatcagttta aagtttctta
     6001 tctatgggct tttagccagt tttttaggga caactttagg tattattggg ggaacttacc
     6061 tcttatctac cttgatttca gagatcttaa caggagcttt gactattgga aagactcacc
     6121 tttatagtta ttggttttat aatggcatag cttacttgct ggctatgtta tctgctgttt
     6181 taccagccta cttaattgtc aaaaaggaat tattcctcaa tgcagctcag ttattgctgc
     6241 ccaaacctcc tagtaagggg gcaaaaatct ggttggaaca ccttactttt gtctggaaag
     6301 ccctgtcctt tactcacaag gtgaccatac gtaatatttt tcgctataaa caaagaatgc
     6361 tgatgaccat tgtaggcgtt gcaggctcag tagccctttt atttgcaggc ttagggattc
     6421 agtcgtcatt agccaaagta gttgagcatc aatttggtga tttaacgact tatgatattt
     6481 tggctgtcgg ttcggccaaa gcgacagcga cagagcaaac tgacttagct agctatctta
     6541 aacaagaacc tattacaggg taccaaaagg tatcttatgc cagcttaacc cttcctgtaa
     6601 agggattacc tgataagcaa agtatttcca ttttatcaag ttcagctact tctcttagtc
     6661 cctattttaa tctgctggat agtcaggagc aaaagaaggt tcccattcca acctctggtg
     6721 ttttgatttc tgagaaatta gcctcctatt acaaggtaaa accaggtgat cagttgatat
     6781 tgactgatcg gaaaggacag tcttataaag tgacgattaa acaggttatt gacatgacag
     6841 ttggccatta cctgataatg tctgatacct attttaagaa tcattttaaa ggattggagg
     6901 ctgctcctgc ctatctgatt aaggtaaaag acaaagatag caagcacata aaggagacag
     6961 ccagtgactt gttaacctta aaagcgatta gagcagtttc acaaaacgtc aatcatatta
     7021 aatctgttca gctagtagtc acctctctta atcaggtcat gaccctcctt gtcttcttgt
     7081 ctattttatt agcaatcgtt atcctttata acttaacgac tattaatatt gctgagcgta
     7141 ttcgagaatt atccactatt aaagttctgg gattttacga tcaggaggtc accttatata
     7201 tttatcgaga aactatttcg ctatccctag taggcattct tttaggtatc tatttaggaa
     7261 aaggcctgca tacttatatc atgacaatga tttcaactgg ggatattcaa tttggtgtaa
     7321 aggttgatgc ttatgtttat ctagtgccaa ttctagtaat ccttagcttg ttagcggtat
     7381 taggtatctg ggttaatcgc catttaaaaa aggttgatat gttagaagct ttgaaatcca
     7441 tagattgatt ggtgaaaaga cagatataga cagcacttga aaagttaatc atattatgat
     7501 agtatctaaa tactataatt taatagaaag atactatgta tggaaaatag cattgaggcc
     7561 tatctagcag atagcagaga aaaggtaaca ttaggcacag ttgttgattg ttttaaagga
     7621 aaagcagtct caagtaaggt tgtgccaggt gatgtgggat tgattaattt atctgacatg
     7681 ggcaccttag ggattcaata tcaccaatta agaactttcc agatggatcg taggcagctc
     7741 ttgcgttacc ttttggaaga cggagatgtc ttaatcgcct ctaagggaac cctaaaaaaa
     7801 gtctgtgttt ttcataagca aaatcgagat gtggtggcat catcaaatat cactgtctta
     7861 cgccctcaaa aactgttaag gggctactat atcaagttct ttttggactc acctattggt
     7921 caagcgctct tggatgtagc ggaccatggc aaagatgtga tcaatctctc aacgaaagaa
     7981 ttgttggata ttccaattcc cgttattcct ttagtgaaac aggactattt gattaatcac
     8041 tacttgagag gattaacaga ttatcatcgt aaactcaatc gagcagaaca ggagtgggaa
     8101 tatattcaga atgaaattca aaaaggatta ggttaggagt cttgtcatgg gttcagttga
     8161 acgtacatta aaaatgacct tggctaccat tgttgccatt ttaattgctt accaacttca
     8221 tctggattat gcaatgtcag cggggatcat tgccctgtta agtgttttag acacccgtaa
     8281 gtccagtttg gtggtcgcta ggaatcgctt gctatctttt ttcctggctt ttgggattgc
     8341 gatgatgtgc tttagcttgt ttggttttac gacagtaggt tttatgtgtt atttgttaat
     8401 tattattcct ttgctctatc actttcagat agaggcagga ctggttccta taacagtact
     8461 tgtgacacat ttgattgcta aaaaaagtat tgcattacct attttatcga atgagtttat
     8521 gctctttttt gtagggacta gtgtcgcttt actatttaat gcttatatgg gtccacaaga
     8581 tcagcaaatt cggtactatc accaaaaagt tgaatcggat ctgaaaggta tcttataccg
     8641 ttttgaaagc tttctactgg aaggaaaagg tcaaaatgaa gggctcttga tcaaaaacct
     8701 tgataaaata ttagatgaag ctctaaaact agtttatcga gaaaggcata atcaactatt
     8761 tcagcagacc aattatcaag ttcattattt tgagatgcga cgacaacaaa atagactatt
     8821 gggacaaatg gctatcaacg taaacacgtt aatgagacaa agtaaggaaa gtattctttt
     8881 gtcacatctt tttcacgaaa ctgcttgtca gctaagcgaa caaaatccgg ctttaacctt
     8941 gattgatgac atcgaacaat tgcttgaaac ctttcgtcat ggtgatcttc ctcaaactcg
     9001 ggaggaattt gagcgacgtg cggttttatt tcagctctta caagacttag agcgctttat
     9061 cttattaaag gtagagtttt atcaggatta tcaaaatgac taaatctcta ttgcacactt
     9121 cttatctatg acagcttggg acttaacttc ctgagctttt ttgctataat aaaatgaaga
     9181 atctcagaat ggagacaaga tgaacgaaat aaaatgccct cattgtcata ccctatttac
     9241 tatcaatgag tcagagtata gtcaattatt ggaacaagtc agagggcaag cctttgatga
     9301 agaattgaaa aaacggctaa tcaatgagat agccttgctg gaagaaaaag cgaagcatca
     9361 attgcatgag gttgtcgcaa aaaaagaaac agctattacc agcttgacaa accaattaga
     9421 gcaaattgaa aaagaacaag cctacctcag acaagaagaa ctggctaaaa aagaccagct
     9481 tattgcttct ttagaagcga aacttgataa attagcctcg caaaatgctt tggaactggc
     9541 caatcaatta gctgagaagg acaaagaagt ggttagtttg accaatcagc tggacaaatt
     9601 agcacttgaa aaagatgcca cgttccagtc aaaacttgct acaatcgaaa aagaacgcga
     9661 tggaatcaaa aaccaattgg cgcttcaagc taaagaaagt gaattgtcgt tggcttcggt
     9721 gcgcagcgac tacgaagcac agttaaaagc ggctaacgag caagttgaat tttataaaaa
     9781 tttcaaagcg cagcaatcta ccaaagcaat cggagagagt ctagaactct atgctgaaac
     9841 agagtttaac aaagtaagaa gctatgcttt ccccaatgct agctttgtca aagataacca
     9901 attgtctagt cgtgggtcaa aaggggacta tatttaccga gaggttgatg ccaatggtgt
     9961 agaaatcctc tctatcatgt ttgagatgaa gaacgaggca gacaccacca aaacaaaaca
    10021 taaaaatagt gattttttca aggagttaga taaagaccgt cgcgaaaaag attgtgagta
    10081 tgctgttttg gtaagcatgt tagaagctga taatgattac tacaatacag ggattgttga
    10141 tgtcagtcat gagtatcaaa agatgtatgt ggttcgtcct caactcttta ttcagttgat
    10201 agggattctg cgaaatgcgg ccctgaatag tttacactat aagcaagagt tggccttggt
    10261 taaggaacaa aatattgaca tcactcactt cgaagaggat ttggaccaat ttaagaatgc
    10321 ctttgctaag aactatcagt ctgccagcaa caactttaaa aaggctattg acgagattga
    10381 taaatcgatt aaacgcatgg aggaagtgaa acgcttttta accactagtg aaaatcagtt
    10441 acgcttagct aataataaat tagaggatgt ttcagttaaa aaactgaccc gccaaaaccc
    10501 aaccatgcga gagaaatttg aagccctcaa ggaccagtaa gcctgaaagt gagtctttcc
    10561 ctgctaaaat tggttaagcg tttattttgg caaaactgat gataaagcgg tagaatagaa
    10621 tcagtaacaa ttactaatta gagagaaaaa tagacatgat aaatggaatc attaatttaa
    10681 aaaaagaagc cggcatgacc tctcatgacg cagtttttaa attacggaag ttattacaag
    10741 aaaaaaagat tggacatggg gggaccttag atcctgatgt ggtcggtgtt ctaccaattg
    10801 cagttggtaa ggctactcgt gtgatcgaat acatgacaga agctggtaaa gtttatgaag
    10861 gacaagtgac tctcggttac tcaacaacga ctgaggatgc tagtggagag gtagttgcga
    10921 ggtcctcttt gccagctgtg ctaacagaag aactcgttga tcaaacgatg acgactttcc
    10981 ttgggaaaat cacacagacc ccacctatgt attcagccgt aaaggttaat ggccgtaaat
    11041 tatacgagta tgcgcgtgct ggtgaaagtg tggaacgtcc tagaagagaa gtgactattt
    11101 ctctgtttga acgcaccagc cctttgaatt ttactgaaga cggtctttgc cgattctctt
    11161 ttaaagttgc ttgtagcaaa gggacttatg tgcggacctt agcagttgat ttaggtcgag
    11221 ctctaggggt agagagtcat atgtccttct tgcagcgatc agcttcagca ggattaaccc
    11281 tcgagactgc ctatactttg ggagaaattg ctgatatggt ttctaaacaa gagatgtctt
    11341 ttttgttacc gatcgagtat ggcgttgctg atcttcctaa aatggttatt gatgatactg
    11401 aattgactga aatttcattt ggtcgccgtc ttagtctccc tagtcaagag ccactgttag
    11461 ctgcttttca tggcgaaaaa gtaattgcta ttttagaaaa aagagatcaa gaatacaaac
    11521 ccaaaaaagt tcttatttaa atagtttgag taagtagaat ggataattat ggaaattgaa
    11581 tatatcaaag attatcgtga tattaaccaa gaagatgata cagtcttgat attgggatat
    11641 tttgatggat tacaccgtgg tcataaagcc ttatttgaca aagcaagaga ggttgcaaat
    11701 aaagaagggt taaaagtagt cgtttttacg tttacagagt ctccgaaatt ggctttttcg
    11761 cgtttttctc ctgagttatt gcttcatatt acttatccaa agaagcgtta tgaaaaattt
    11821 gccgattacg gtgtaaataa attatatttg gttgatttta cttctaaatt ctctaaggtc
    11881 tcatctgatc attttataac tcattatatt aaaaacctga aagcaaagca tattgttgtc
    11941 ggttttgact ataagtttgg gcataatcgt acagatagtg attatttaac cagaaatttt
    12001 gaaggacaag tttataccat tgaggaaata aaagaagatc atcgaaaaat ttctgctaca
    12061 tggataagga agcttattca agaaggtaat gtagttaaag caaaccactt gttaggctat
    12121 gacttatcga caaggggaag agtcgttcac ggggatgcgc gtggccgtac tattggtttc
    12181 ccaacagcca atctagctcc aattgacaac acatacttac cagctgatgg agtctatgtt
    12241 acaaatgtta ttgttgctaa taaaatctat cgctctatga cgagtttagg taaaaatgtg
    12301 acatttgggg ggaaagagtt gcgtctagaa gttaacattt ttgactttga cgaagagatc
    12361 tatggagaaa ttattgagat tgtttggtta gataagattc gagacatgga aaaattcgag
    12421 ggaatcgaag atttgactga tagattggaa tatgataaac gaacagcatt aaattggaaa
    12481 aaagatagca aattatctta aatttttgta taataaggta agtaaatttg atagaggaaa
    12541 aatatggtta ccttattttt atcacctagc tgtaccagtt gtcgtaaagc aagggcatgg
    12601 ttagtaaaac acgaagttga ctttcaagag cataatatta ttacaagtcc attaagccgt
    12661 gatgaattaa tgtcaatcct ctcttttaca gagaatggaa cggaggatat tatttcaaca
    12721 cgttcaaagg tttttcaaaa acttgatatt gatgtagaag agctttcaat ttcagattta
    12781 attgatttaa ttgctaaaaa tccaagtctt cttcgtcgcc ctattatcat ggatcaaaaa
    12841 cgcatgcaaa ttggttttaa tgaagatgaa attagagcgt ttttatcgag agattatcgc
    12901 aagcaagaac tacgtcaagc aacgataaaa gcagaaattg aggggtgata tgtcaggtaa
    12961 ttattattat ccacttgact taagttggag cactgaagaa atatcctcag tgcttcattt
    13021 tttgaataaa gtggaattag catatgaaaa aaaagtagat gcaaaacaac tcctagatag
    13081 ttataagact tataaaacca ttgtcaaaag taaagctcag gaaaagcaaa tcgatcgtga
    13141 ttttcaaaaa gttagtggtt attcgaccta tcaagttgtt aaaaaagcga aggcaattga
    13201 gaaaggattc ttttcccttg gaaactaaat acgcatttgc aaggcaaatc attaaagaag
    13261 cagggctttt tatcaagtca aaaatgtcag agcagctaga tattcaggtg aaaacacaat
    13321 ttgatgatct ggttaccaat gttgatcaag aaactcaaca gttactgatg gatcgtattc
    13381 atcagaccta tccttgtgat gccattttag ctgaagaaaa tgacgttcgt caccccatta
    13441 atcaaggaaa tgtttgggtc atcgatccca ttgatggaac ggttaacttt attgtgcagg
    13501 gatcacagtt tgcagtgatg attgcctatt atgaacaagg aattggtcaa tttgggctta
    13561 tttatgatgt gatggcagat caattactag ctggtggtgg tgattttgaa gttactttaa
    13621 acggtgataa gcttccagct taccaagaaa aacctttaga gcgtagctta attggctgca
    13681 atgcaggcat gtttgccaga aatgatcgta accttgctca tctaattgca aagactttag
    13741 gtgtaagggt ttatggtggt gcaggtatct gcatggttaa ggtcatgaag caggaattac
    13801 tggcctattt ttcatttatc caaccatggg attacgcagc agcaaaagta ctaggcgata
    13861 aactgggtta tgttttacta actattgacg gatatgagcc tgattttcaa acacgtcaaa
    13921 aaatcatgtt tgttcctaaa tgccaactca ctaggatagc gtcttttcta acaaaggact
    13981 ctgccatcac acttgaagat caatagaaat gatgtcatta ccaaaagaat ttattaacac
    14041 ttatcaagca atactaggca aagaattaga agatttcttg gcaagtttta accaagagcc
    14101 ggtcaatgct tttcggatta accccttaaa gaatcaacta aaaacctttg aacaccccat
    14161 tccaaatacc ttatggggat attatggtaa actatctggc aagtctccag agcatgtgtc
    14221 ggggttggtt tattcccaag aaccagcggc tcaaatggtg gcacaagtag cggctcctca
    14281 aaaggggagt cgtgttttag acttggcagc tgcaccagga ggaaaatcaa ctcatttatt
    14341 agcttattta gacaatacag gtcttttagt cagcaatgaa atttctaaga agcgcagcaa
    14401 ggttttagtt gaaaatatcg aacgttttgg cgctagaaat gttgtggtga ctaatgaatc
    14461 cgcagatcgt ttagccaagg tattttctca ttattttgat actatcgtct ttgatggacc
    14521 atgttctggt gaaggaatgt ttcgcaagga ccctgatgct attcaatatt ggcatcacgg
    14581 gtatcccgca gaatgtgcca agttgcaaaa atctatttta gaagacgcct tagccatgtt
    14641 aaaaccagga ggagaattga tatactccac ctgtacttgg gctcctgaag aaaatgaaga
    14701 tgttgtgcag tggctcttag agacttatac ctttttagaa ttggtcgatg ttccaaaact
    14761 aaatggaatg gttagtggta tcggacttcc agagactgct agaatgtacc ctcatcgtta
    14821 tcaaggggaa gggcaatttg tggccaagct aaaagataag cgtcaagaag gacaaagcac
    14881 taaactaaaa gcacctaaat ccaacttgat caaagaccag ttacgtcttt ggaaaatgtt
    14941 tgaaaaagac catctaaacc ttaccctatc aggaacacta caaacctttg gtgattacct
    15001 atacctcttg ccagatggtc ttcctgcttt agatggcctt aaaattgctc ggaacggttt
    15061 agaattaggc gtcttcaaga agaaacgctt tgaaccctct tacgccttgg gattagcttt
    15121 aaagcctgat gaggtccgat catctattga gcttagagag gaagacttta gaccttatgt
    15181 gtcaggtaac gtcattactt tgccccaatc ttatccaaca ggctggtacc aattactcat
    15241 taatggcaat ggtctaggat ttgccaaggt cgttgacaag accatcaaaa ataatttccc
    15301 taaagggtta agattttagc gtaaaaaata agattaaaaa gttaaatatt taaagaaaaa
    15361 atgctttcaa agcataggt
//
LOCUS       DAUGQX010000041        14710 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUGQX010000041 DAUGQX010000000
VERSION     DAUGQX010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14710
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.041"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1141
                     /locus_tag="VIA51_001385"
     CDS             <1..1141
                     /locus_tag="VIA51_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEQ8683324.1"
                     /translation="FVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAYIS
                     KQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQEGDGFGGV
                     TIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDTETAHLYGE
                     LAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLNLFSYTAAF
                     SVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKL
                     IFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFK
                     KQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            1138..1824
                     /locus_tag="VIA51_001386"
     CDS             1138..1824
                     /locus_tag="VIA51_001386"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEQ8683325.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            1918..3084
                     /gene="aroC"
                     /locus_tag="VIA51_001387"
     CDS             1918..3084
                     /gene="aroC"
                     /locus_tag="VIA51_001387"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEQ8683326.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            3145..3486
                     /locus_tag="VIA51_001388"
     CDS             3145..3486
                     /locus_tag="VIA51_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEQ8683327.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADVSASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            3707..5059
                     /gene="gorA"
                     /locus_tag="VIA51_001389"
     CDS             3707..5059
                     /gene="gorA"
                     /locus_tag="VIA51_001389"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEQ8683328.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEM
                     AVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(5147..6415)
                     /locus_tag="VIA51_001390"
     CDS             complement(5147..6415)
                     /locus_tag="VIA51_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8683329.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(6445..6885)
                     /locus_tag="VIA51_001391"
     CDS             complement(6445..6885)
                     /locus_tag="VIA51_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683330.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITISRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTTPSHNETTPTAPETPSATEGTQIPNATGAEDANTGLPTNP"
     gene            7120..8262
                     /locus_tag="VIA51_001392"
     CDS             7120..8262
                     /locus_tag="VIA51_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8683331.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKNAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKSLS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            8274..9488
                     /gene="thiI"
                     /locus_tag="VIA51_001393"
     CDS             8274..9488
                     /gene="thiI"
                     /locus_tag="VIA51_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEQ8683332.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGTGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            9526..10818
                     /locus_tag="VIA51_001394"
     CDS             9526..10818
                     /locus_tag="VIA51_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEQ8683333.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    10923..10997
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            11032..11346
                     /gene="rplU"
                     /locus_tag="VIA51_001395"
     CDS             11032..11346
                     /gene="rplU"
                     /locus_tag="VIA51_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEQ8683334.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            11358..11684
                     /locus_tag="VIA51_001396"
     CDS             11358..11684
                     /locus_tag="VIA51_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEQ8683335.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            11712..12005
                     /gene="rpmA"
                     /locus_tag="VIA51_001397"
     CDS             11712..12005
                     /gene="rpmA"
                     /locus_tag="VIA51_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEQ8683336.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            12353..13267
                     /locus_tag="VIA51_001398"
     CDS             12353..13267
                     /locus_tag="VIA51_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8683337.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            13264..13722
                     /locus_tag="VIA51_001399"
     CDS             13264..13722
                     /locus_tag="VIA51_001399"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEQ8683338.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLLICLWKEEDYGN"
     gene            13712..14602
                     /locus_tag="VIA51_001400"
     CDS             13712..14602
                     /locus_tag="VIA51_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8683339.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
BASE COUNT         4545 a         2572 c         3191 g         4402 t
ORIGIN      
        1 ttttgtcgaa aagaagctga cagcaggggt acaattatta gatgaaaaag atttttctaa
       61 tataaaggaa aaaaatcagt tggttcaact ggtgaccaag tccaatcgtc ccattggaac
      121 agcatatatc tctaagcaaa ataaaggaat tggttggtat ctaggaccag aaaaaatcga
      181 cttgtctatc tcttattttg ttagtctatt ttcagttgct aaggccaaaa gacaagattt
      241 tgctcaatcg gacgagacca atgcttatcg cctttttaat caagaaggag acggttttgg
      301 tggagtaaca attgatcttt ataaagattt tgcagtcttt tcatggtaca atgcctttgt
      361 ctatgacaaa aaagaaatga ttatggaggc ttttcaacag gtttttcctg aagtcaaagg
      421 agcttatgaa aagtgtcgct ttaaaggtcc agatactgaa actgctcatc tgtatggtga
      481 gctggcacaa gaaacctttt cgattttaga aaatggcata gcctatcaag tcttcttgaa
      541 tgagggctta atgacaggta tttttctaga ccagcatgat gttagaagag cactagtaga
      601 tggtttagct atgggcaagt cccttcttaa cctattttcc tatacagctg ccttttctgt
      661 agcagctgct atgggtggtg ctatcgagac cacttctgtg gacttggcta aacgatcgag
      721 agaattatca ctagctcatt ttgagcataa ccagttaaac ttagcctcac atcattttgt
      781 ggtgatggat gtttttgaat acttcaaata tgccaaacgg aaaaaattaa tctttgatgt
      841 gattgtgatt gacccaccaa gctttgctag aaataaaaaa caaactttct ctgtgagcag
      901 ggactaccac aaattaatca cagaggcctt ggacatattg agtcctaagg gaactattat
      961 agcttcaaca aatgctgcta atatgactgt tagccagttc aaaaagcaaa ttatcaaagg
     1021 atttggaagt cgtcgtcctg agtctatgac tctccagcag cttccgagtg actttactat
     1081 caataaagca gatgaaagaa gtaactattt aaaggtattt actataaagg tacgagaatg
     1141 agaattgtag caccagtcat gccaagacat tttgacgagg ctcaagccat tgatatttct
     1201 aaatatgaag atgttaattt aattgaatgg cgagcagact ttcttcccaa ggatgagatt
     1261 gtcgcagtag caccagctat ttttgaaaaa tttgccggaa aagaaattat ctttaccctt
     1321 cggaccgttc aagaaggggg gaatattacc ctttcaagtc aggagtatgt tgatattatc
     1381 aaagaaatca atgctattta taatccagac tatattgact ttgagtattt tacgcacaag
     1441 tcagtatttc aagaaatgct tgattttcca aatcttattt tgtcttatca caactttgaa
     1501 gagactcctg aaaatttaat ggaagctttt tcagaaatga ccaagttggc accgcgtgtg
     1561 gttaaaattg ctgtgatgcc ccagagtgaa caagatgttc tagatttgat gaactatacc
     1621 agaggcttta agacgctcaa tcctgagcaa gaatttgcaa ctatatctat ggggaaatta
     1681 ggaagattgt ctcgttttgc gggagatgtc attggctctt cctggacata cgtttcatta
     1741 gatcatgtta gcggtccagg tcaagtgact ctcaatgata tgaaacgtat tattgaggtc
     1801 ttagaaatgg atatctctaa ctagtgaatg gtctaaaaat attatttcta caatagttaa
     1861 gaaatgatgt ttttagatta atgtttttaa aataagtgga accaaaaagg agaaaaattg
     1921 cgttatttaa cagcaggaga atctcatggg ccatccttaa cagctattat tgaaggtata
     1981 ccagcaggat taactcttca tccagcggat attgatcacg aattacagcg acgtcaagga
     2041 ggttatggcc gtggtgccag aatgtctatt gagactgatc gggttcaaat atcctcagga
     2101 gttcgtcatg gtaaaacaac aggggccccc attaccttaa cggtaattaa taaggaccac
     2161 caaaaatggc tagatgtcat ggctgtagga gacattgaag agactctcaa gttaaagcgt
     2221 cgtgttaagc atcctagacc aggacatgcg gatttggtag gaggtattaa atatcatttt
     2281 aacgatttaa gagatgcttt agagcgttcc tcggctagag aaacaacgat gagagtggct
     2341 gtaggcgctg ttgctaaacg tatcttagct gaacttggaa ttgatatgtt acatcatatc
     2401 ttaatatttg gtggtataac gatcacaata ccttctaagc tctcttttag agagctgcaa
     2461 gaaagggctc tccattcaga attatctatt gttaatccaa agcaagaaga agaaattaaa
     2521 acgtatattg ataagataaa aaaagaaggg gataccattg gtggtattat cgaaacgata
     2581 gttcaagggg tgccagcagg tcttggatct tatgtccaat gggataaaaa attagatgcc
     2641 aagctggctc aagcagttct ttccattaat gcttttaaag gggtggaatt tggagctggg
     2701 tttgatatgg gattccaaaa gggctctcag gtaatggatg aaatcacctg gacacctacc
     2761 cagggctatg gtcgtcaaac aaaccactta ggtggctttg aaggtggcat gaccacagga
     2821 caacctcttg ttgttaaagg ggttatgaag cccattccta ctttgtataa accactcatg
     2881 tcggtagata ttgatagtca tgaaccttat aaagcaacgg tggaacgctc tgatccgacg
     2941 gccttaccag ctgcaggggt tatcatggaa aatgtggtgg cgacggtgct tgccaaagag
     3001 attttagaga ctttttcttc tactaccatg tctgaattgc aaaaagcttt ttcggactat
     3061 cgtgcctacg tcaagcaatt ttagatagcg agatactggc ttttatggta tcatacaggt
     3121 attaatgaac aaaaggagac tgtcatgtca caagaaattt atgactatgc taatcaactt
     3181 gaaagagcag ttcgtgctct gccagaatac caaaaagtgt tagaagtaaa agaggccatt
     3241 caagcagacg ttagtgctag cgaactgttt gatgagtttg tcgctatgca agaaaaaatc
     3301 caagggatga tgcaatcagg ccaaatgcca acggctgaag aacaaacaag cattcaagaa
     3361 cttagccaaa agattgaagc taatgaccag ctaaaagctt attttgaagc gcagcaggcc
     3421 ttatctgttt acatgagtga tattgagcgt attgtatttg ctccgttgaa agatttagtc
     3481 aagtaagcca attaagatag gaaaaaaaca gattgctggc agctcgtcag gatctgtttt
     3541 ttagtgttta ttttctttgt atcagaaagt tgagcctctt tcttatttgt gatatagtca
     3601 aataaagtga ccaaaatagc aggccagtag tggctttaat gaaggcaagt tgtctgctaa
     3661 ctggctgtgc taaaacatca gtattagaaa gtaaaaggtg ataaaaatgg ttattcctta
     3721 tgattatatt gttattggtg gagggagtgc aggtattgct tctgcgaaca gggcagccat
     3781 gcatggggcc aaagtattgt tagctgaagg taaagagatt gggggaacct gtgttaacct
     3841 aggctgcgtt cctaaaaaag tcatgtggta tggcgctcaa gtagcagata ttttagggac
     3901 ttacgctaag gattatggat ttgactttaa agagaaagca tttgatttta aacaattgaa
     3961 agcaaatcgt caagcttata ttgatcggat tcatgcttct tatgagcgag gctttgagca
     4021 gaatggtgtt gaccgtattt atgattatgc tgttttcaaa gatgctcata cggtagaaat
     4081 tgcagggcag ctttataccg caccgcatat tttgattgcc acaggaggac atcctgtttt
     4141 tccagatatt gagggggcac aatacggtat cagctcggac ggcttttttg ccttagatga
     4201 ggtaccaaaa cgtacggctg tggttggggc aggctatatt gctgtggaac ttgctggtgt
     4261 tttgcatgct ttgggatcga agacggattt gtttatccgt cacgatcgac ctttaagaag
     4321 ttttgacaaa accattgttg atgtcttagt tgatgaaatg gcagttaatg ggccgcgttt
     4381 acacactcat gcagaagtgg caaaggttgt caaaaatact gatgagtcct tgacccttta
     4441 cctcaaagat ggccaagaag ttgaggttga ccagctcatt tgggctatcg gtcgcaagcc
     4501 taatctagaa ggttttagtc ttgacaaaac tggagtgacg ttaaatgata aaggttatat
     4561 tgagacagat gcctatgaaa acacgtctgt caaaggtatt tatgccgtgg gagatgttaa
     4621 tgggaaactg gctttaactc cagttgctgt ggcagctgga cgtcgcctat cagagcgtct
     4681 tttcaatggc aaaacagacg agaaattgga ctaccaaaac gttgctactg tgatttttag
     4741 tcaccctgtt attggctctg ttggcttgtc agaagaagca gcagtcaaac agtatgggca
     4801 agaagcagtt aaaacatatc aatcacgttt tacgtctatg tttactgcta tcactaacca
     4861 tcgccaacct tgtctgatga agttggtaac agtcggagat accgaaaaaa tagttggtct
     4921 tcacggaatc ggatacgggg ttgacgaaat gattcagggc tttgcagtag ccatcaaaat
     4981 gggagcaacc aaggcggatt ttgataacac cgttgctatt cacccaactg gctcagaaga
     5041 atttgtcacc atgcgctaaa aaatgtagcc taaggcaata aaaaatgatg ttaacagttt
     5101 ttgaggaaag tcttctaaac tgctagcatc gttttttgtt aggtgattag gggaatatgt
     5161 ttttaaagat atttgcgttg ctcagacaat attgccttac ctcggagata aaataaagtg
     5221 accctgtaac aacaaagagt tcatcagatg ttacggaacc ttgtaaccag tctctgtaat
     5281 cttttacctg tgggtattta tcaggataat cctctaaaag atttgcttca gggaaatcaa
     5341 aagtcgtgac agatacttca aaagtatcta gttgagccag caagtcggct aaaggcttac
     5401 gtttgagacc tgcaaagaga atatgaatag gacgtttggg aaattcttct tgcagtagag
     5461 actttaattt agcaatggaa tctggattgt gagcgccgtc taatagaaga ttaggttgaa
     5521 taaattcgga ccggccaggc caagttgttg cctcaattcc tttttgaatc gtttttggag
     5581 atattttagg aaaggatttt ctaagtaatt gagctgtcat aatggctaaa caggcattcg
     5641 ctttttgatg ttgacctaat agtttgagac ggagtttggt taaattcaag ttatcgtgtt
     5701 gaaaggaaaa cgtcttttct gaaggattga gcaaaaaatc ttttcctaat tgatataagc
     5761 gtgaaccggc tttttgggta acttgttgaa agacttgact agcctcctgc tcaagttgac
     5821 cgataataac gggttcttta gctttgataa cttctgcttt ttggtgagca atttctgcta
     5881 ggctataacc taaacgttct tggtgatcaa aactaataga agggcatacg acggccagag
     5941 catgaaaaac attggttgcg tcggttttcc caccaatccc tgcctcaata atggcaatat
     6001 caacaggttt aagattggca aagtagcaaa acattatgag cgtcactaac tcaaactcgg
     6061 taggtctatc ccaatttgtt tcaagagaca ttttagtgag aatgggtcta atcacgctca
     6121 cacattgcgc caattctagg tctgaaatgg gctggccatt aaggcaaatc cgatcgtgaa
     6181 aagagataat aaaaggagat gtaaaggttc cgacctgata accagaagtt gacaggatat
     6241 gctgtaagta ggctgtcaca gagcccttgc cgttagttcc aacaacgtga atagcaggga
     6301 atttgtcttg tggccggcct agtgcctcaa gtaaccaagc cattctggcc aaatcggtct
     6361 tgcgaccatt agccttaaag gtatgaatcc aggaaatgct atcataggta gtcattacta
     6421 tttcttgtcc ttctaacaat gcttttaagg gttcgtagga agaccagtat tagcatcttc
     6481 agctccagtt gcattaggaa tttgcgtccc ttcagtggct gatggtgtct caggagctgt
     6541 aggagttgtc tcgttgtgag aaggtgtggt agaagatgac ggaagagttg tcttattatc
     6601 atctgtggtt tctgaagtac ctgtatggtt ttgattaccc tgagaagact ctttttcaat
     6661 aatcttgaca atggtattac tcgattcttt gggtgtatca ttagaggtct tatctggtac
     6721 aggctgcagt gctcttgaaa tggtaatggt tgccacgatg atactcaaaa tactaccaat
     6781 aagtgcaatg gatttttgga aagctgtaaa acctgtttta atatgctcgg tagggacacc
     6841 tcctgattta cgaggttttt gttgacggga ataacgtgat gacatatttt tctcctttaa
     6901 aatcatcgta atgccaagat taaggaggag gaaacagaag tcctagctcc tctttaacac
     6961 ttcatctatc agtataatct agaaaaaaag tgaagtcaac ggtttacctt atgtctagga
     7021 caaggaagtc ctttgggctt attgtaatac gaatattctt gatttcattt tagctatttt
     7081 gtgatagaat aaagtattga gtaaaaatga aggtgacaca tgatttattt tgataatgca
     7141 gccacaacca taccttatgg agaggctctt aaaacttacc aagaagtagc aacaaaaata
     7201 tatggcaatc cctcaagtct gcaccaatta gggacaaatg cgtctcgcat tttagaagct
     7261 tcccgtaaac agattgctgg tttgttgggt gttaagtcag aagaaatctt ttttacgtct
     7321 ggtgggactg aaagtgctaa ttgggctatt aagggaattg cttttgaaaa aaacgctttt
     7381 ggcaaacata ttattatctc agccattgaa caccctgccg tgagtgaaag tgtcaaatgg
     7441 cttctcacac aaggattcga agtttcttat gctccagtga caacacaggg agttgttgat
     7501 gtgaatgctt tagctgagct gattagacca gacaccatct taatctcgat tatggctgtt
     7561 aataatgaaa tgggagctat ccaaccgatt agagccattt caaacctatt ggctaaccaa
     7621 ccaacgatca cctttcacgt tgatgctgtt caagccattg gtaaaatacc actctgtgat
     7681 tatatgacta atcgtgtgga tttggcttct ttttcagggc acaaatttca tagtgttcgt
     7741 ggtgttggct tcctttataa aaaagcaggc aagcgactca atcctctctt gtcaggcggc
     7801 ggccaagagc aggagttacg ttcaaccact gaaaatgttg caggaattgc tagcatggcc
     7861 aaagcattaa gaatagtcac tgaaaaacaa gtgagcgtct tacctaaact aacagcgatg
     7921 cgagatgtga tttacaaatc tttgtccgct tacccagatg tgacagtatt ttcagctcaa
     7981 gaaggctttg cgcccaatat tttgaccttt gggattagag gggttcgagg agaagttatt
     8041 gtccacgcct ttgaaaaata tgagatttat atttcgacca caagtgcatg ttcgtccaaa
     8101 gcaggtaagc cagcaggaag cctagtggct atggggattc ctgtaaaaac tgcccagaca
     8161 gccgttcgta ttagtctaga cgatgacaac gatatgggac aagtagagca gtttttgacc
     8221 atattcaaac agatttatga taaaacacag aaagttaggt aagattaggt aagatggact
     8281 attcagaaat tatggttcgc catggtgaac tatcaactaa agggaagaat cgcatgcgat
     8341 tcattaacaa acttaaaaac aatattcaag acgtactggc tcctttccca gccattactg
     8401 tccgttcaga tcgtgatagg acccatgtgt ctctaaatgg cacagattat cagcctattg
     8461 tagaagcttt aaagctggtg tttggtgttc aagctctatc tcctgtttat aaacttgaaa
     8521 aaagtgtccc tcttttggta acagctgttc aagatatcat gacttctctt tatcgtgatg
     8581 gactgacgtt taagattgcc actaagcgta gtgatcacgc gtttgaattg gatagtcgtg
     8641 agcttaacag tcttcttggt ggagctgttt ttgaggtttt accaaatatc caagcccaga
     8701 tgaaacatcc cgatgtgact ctcaaagtcg aaattcgtga tgaagcagct tacatttctt
     8761 atgaagagat taagggaaca ggcgggttac cggtaggaac gtcagggaaa gggatgctga
     8821 tgttatcggg cggtattgat tcaccagtag ctgggtattt agcccttaaa cgtggccttg
     8881 atattgaagt tgttcatttt gctagccctc cgtacaccag tccaggtgcc ttggctaaag
     8941 cccaagacct tactcgtcga ttaactcgtt ttggtggaaa tatccaattt atcgaggttc
     9001 cttttacaga aattcaagaa gaaattaaaa ataaggcacc agaggcttac cttatgacat
     9061 taacccgccg ctttatgatg cgcatcacag atgccattcg tgagcaacgt aagggtcttg
     9121 ttattgttaa cggtgagagc ctaggtcagg ttgctagtca aacccttgaa agcatgcagg
     9181 ccattaatgc ggtaacatca actccaatta ttagaccagt cgtgacaatg gataaacttg
     9241 aaattatcga gatggctcag gcgattgata cttttgacat ttctattcaa ccgttcgaag
     9301 attgctgtac tatttttgca ccagaccgtc ctaaaaccaa ccctaaacta ggtaatgctg
     9361 aaaaatatga agaacgcttt gatattgatg gtcttgtcca gcgtgctgtg tcaggaattg
     9421 ttgtcacaga aatcacacct gaaatcgtca atgatgaggt tgaaaatctc attgatgctt
     9481 tactttaaaa gaaaagatca agtgtaaatc ttttagtagt cagtaatgat actattgaaa
     9541 agcctctata agggcttttt tgctgcaatg aaggaggaaa attttgaggc aagatgttat
     9601 aatagagaaa aaggagggtg tgtcttgatt aaaactatgc aatacaaaaa aacgatggca
     9661 acagttgttg ctcttatcgt cgcacttttg ctatttggct tgatttatga tttacttggg
     9721 gttcaaaaaa atgagctagc agctcaaaaa tctgctcagc caaaggtcaa aacagcgcgt
     9781 gttgtagcta atggcgacat tttaattcat gatattctct acatgagtgc tagaaaagct
     9841 gacgatacct atgatttcac tccttatttt gaatatgtta aggactggat tagcggtgct
     9901 gacttagcta ttggagatta tgaagggacc attagcccag attatccctt agcaggctat
     9961 cccttattca atgctccaga agagattgca ggtgctctga aaaatactgg ctatgatgta
    10021 gtcgatttag cccataatca tatcttagat tcccaattag acggtgccct taacactaaa
    10081 aaggtttttc atcaattagg tatagacagt attggcatct atgacaagga tcgttcaaaa
    10141 gaatccttct taattaaaaa tgtcaatggt atcaaaattg caattttagg ttattcttat
    10201 ggttataacg gcatggaggc cacacttagc caagaagact atgagaaaca catgtctgat
    10261 ttagatgaag ctaagataaa aaaagaactt cagctagctg aaaaaaaggc tgacgtgacc
    10321 attgttatgc cacaaatggg aacagaatat gccttagaac cgacagcaga acaaaaagaa
    10381 ctttaccaca aaatgattga ttggggagct gacgtcgtcc taggaggcca tccgcatgtt
    10441 attgaacctt cagagacagt tataaaaggt aggcaaaaga aattcattat ttactctatg
    10501 ggaaatttta tttcaaatca gcggcttgaa accgtagatg atatctggac tgagcgtggc
    10561 ctattgatgg accttacttt tgagaaaaaa gataacaaaa caaaaattaa aacagttgag
    10621 gcccatccaa ccatggtttt agccaaaggt aaaggcattg tgggtaaaga aggttttgaa
    10681 ctatacaatt atcgaacaat ggttttagaa gattttatca aaggtggaaa ataccacgac
    10741 aagattgatg aggaaaccaa agcaaaagta gcacttgcct atcaggaaat taatgattta
    10801 gttaacctga aatggtaacg tttggtggtt tagcatctaa cgataaaaaa tagagattaa
    10861 acttaatttt tccttgataa aaagcagtta tggtgctaaa atagtaacgt tgactaaatg
    10921 cacatcctgt gcaaccgcgc gaaaatcgtt gtcaagtaga ccaagtctca cgattccagg
    10981 cgagtcttca cagagggaaa cctcaaacaa aaattttata ggaggtgcat catgagcaca
    11041 tacgcaatca tcaaaactgg tggaaaacaa gttaaagttg aagtaggtca agcaatctac
    11101 gttgagaaaa ttgacgctga agctggcgca gaagtcactt ttaacgaagt tgttcttgta
    11161 ggtggtgaca aaactgtagt tggtactcca gttgttgaag gagctactgt cgttggaact
    11221 gttgaaaaac aaggaaaaca aaagaaagtt gtaactttca aatacaaacc taaaaaaggt
    11281 agccaccgta aacaaggtca tcgtcaacct tacactaaag ttgtcatcaa cgcaatcaac
    11341 gcttaattta ctagcttatg attaaagcaa tttttactcg ccaaaaaaat ggtcaactga
    11401 gcagtgttac actgacaggt catgctggta gtggtaaaca tggctttgat attgtttgtg
    11461 cctctgttag tactctagcc attaactttg ttaattctct tgaggtgtta gcagattgcc
    11521 aagcattagt agatcttaat gatgttgaag gtgggtatat ggctattaca ataccaccac
    11581 atgacaacaa ggaggaagtt caattattat ttgaatcttt tcttctagga atgactagtt
    11641 tggcgaagga ttcttcgaaa tttgtcaaca ctcaggtcat ctaaatttaa tttaagagag
    11701 gaaacaacat tatgttaaaa atgaatcttg ctaacttgca acttttcgcc cacaaaaaag
    11761 gtggaggttc tacatcaaac ggacgtgact cacaagctaa acgccttggt gctaaagctg
    11821 ctgacggtca aactgtttca ggtggatcaa tcctttaccg tcaacgtgga actcatatct
    11881 acccaggtgt aaacgtaggc cgtggtggag atgacacact ttttgctaaa gttgaaggtg
    11941 ttgtacgttt cgaacgtaaa ggacgcgata aaaaacaagt ttctgtttac ccagtagcta
    12001 aataattgtt taacatcgca ttatataagg ctttccaggt gtctggaaag ccgatttttt
    12061 tattttgcta ctcatttgct acccatattc taaaagccga tgtaggaaga gagcttgtca
    12121 gcagttttat cttttgagga tttagtaaca tgagcgtaga tattcatggt agtttggata
    12181 gtttcacgac caagtgtatt ggattttctt ctatcctact aaagattgta gttgcttatt
    12241 tagagcaata gttctaattg taaaaagtca gcataataaa acaatgtcat aagatgttgt
    12301 tataacgggc tttatggtat aattaaggat actcatttta ggaaggaaag caatgaatat
    12361 tcaacaatta cgctatgtgg tagccatcgc taataatgga acttttcgag aagctgcctc
    12421 taaattgttt gtcagtcagc ctagcttatc agtttctatc aaagatttag aggcggaatt
    12481 agggtttcaa atttttaatc ggactacttc aggaacagtc ttgacaagtc aaggactagt
    12541 tttttatgag aaagctttag aagtagttaa gtcttttgat tcttttgaaa aaaccttttc
    12601 tcaagctgat ctggatcaaa atgaattttc tattgctagc caacattatg actttttgcc
    12661 acctcttatt acagcttttt cgcaacaata cgatggtcat cgtgtctttc gtatctttga
    12721 atcaacaact attcaaattt tagatgaagt tgctcaagga aacagtgaaa ttggtattat
    12781 ttacttgaat gtagacaatc aaaaaggtct ctttcagcgg atggataagc tgggcttaga
    12841 atatgtttct ctaattcctt ttactactca tatttatctt tcaaaaacgc atccattggc
    12901 taatcgcgaa gcgctttatt tgaacgatat tcaaggatta cctgcggtaa ggtttaccca
    12961 agaaagggac gagtatttgt attattctga aaattttgtg gatactagtg aatgccctcg
    13021 tatttataat gtgtcagata gggcaacctt gaacggtatt ttagagagaa ccaatgcctt
    13081 tgcgacagga tcaggttttc tcgatcatcg gagtgttaat gggattaaag tgatacctct
    13141 agctgatcat attgacaatc aaatgattta tgtcaaacga aaagataaaa acctttctgt
    13201 tgctggggcc acttttgtga ctattttaaa agactatttt gataaaagaa ggaaggcctt
    13261 aacatgaaaa aacgattgtt tgtgcttagc ttgatcctcc ttgtagcttt ggatcaactt
    13321 agtaaatttt ggattgtttc tcatatagcg cttggagaag tgaaaccctt tatcccaggt
    13381 atcgtcagct tgacttactt gcaaaacaat ggggctgcct tttccatatt gcaggaccag
    13441 caatggttct ttgttgtcat aacggtttta gttatcggtt atgctattta ttaccttgct
    13501 actcatcccc atttaaatat ctggaaacaa ttagctctct tgcttattat ttctggtgga
    13561 atcgggaatt ttattgatcg tttgcgttta gcttacgtga ttgatatgat tcatttagac
    13621 tttgtggatt ttgccatttt taatgtggca gattcatacc ttaccgttgg tgtcatatta
    13681 ttattgatat gtttatggaa agaagaggat tatggaaatt aatgtgataa catcggggca
    13741 acgcttggat aaggcactag ctgatttaag tcccctgtca cgtggtcaag ccaatgacca
    13801 aattaagcaa ggccttgttt tagttaatgg tcagcaaaaa aaggctaaat atacggttca
    13861 agcaggagat gtgatttgtt ttgaactccc taaagaagaa gtcttagagt accaagctca
    13921 gaatattccc ttggacatta tctatgaaga tgatgctctc gccattatta acaagccaca
    13981 gggaatggta gttcaccctt cggcgggaca cccttcagga acaatggtta atgccttgat
    14041 gtatcatatc aaggatttgt cctcaatcaa tggtgtggtt cgtccaggaa ttgttcatcg
    14101 gattgataag gacacctccg gtctcttaat ggtagctaaa acagatgcgg ctcatcaagc
    14161 cttagcagaa gaattgaagg ctaaaaaatc tctcagaaaa tacctcgcca ttgtccatgg
    14221 aaacctaccg aatgatcgcg ggatgattga agctcctata ggtcgtagcg aaaaggaccg
    14281 taaaaaacag gctgttactg caaaaggcaa agaagcagtg acacgtttta cagtgctaga
    14341 acgttttggc gattacagtc tagtggaatt acaactggaa actggtcgaa cgcaccaaat
    14401 tcgtgttcat atggcctata ttggtcatcc tgttgctggg gaccctttat atggaccacg
    14461 taagacacta tcaggtcatg gccaatttct tcatgcaaaa acattgggat taacgcatcc
    14521 tatgacagga aaagaaatga tatttactgt tgaagctccc gaaatttttc aaaaggtgtt
    14581 aaagctgcta agaaaaaaat aaacagcgag gagtagccat tatttttagt cttatatctt
    14641 tgtgtaaagt ttttaacatt ataaaaaata ctaaaaagca tttacgataa gccaggaaat
    14701 atgagaagtc
//
LOCUS       DAUGQX010000042        14571 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUGQX010000042 DAUGQX010000000
VERSION     DAUGQX010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14571
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.042"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            33..1229
                     /locus_tag="VIA51_001401"
     CDS             33..1229
                     /locus_tag="VIA51_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEQ8683340.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            1295..2002
                     /locus_tag="VIA51_001402"
     CDS             1295..2002
                     /locus_tag="VIA51_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEQ8683341.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            2065..3120
                     /gene="prsA"
                     /locus_tag="VIA51_001403"
     CDS             2065..3120
                     /gene="prsA"
                     /locus_tag="VIA51_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8683342.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            3507..6125
                     /gene="alaS"
                     /locus_tag="VIA51_001404"
     CDS             3507..6125
                     /gene="alaS"
                     /locus_tag="VIA51_001404"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEQ8683343.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYDPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAEIV"
     gene            6486..6701
                     /locus_tag="VIA51_001405"
     CDS             6486..6701
                     /locus_tag="VIA51_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683344.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            6698..7459
                     /locus_tag="VIA51_001406"
     CDS             6698..7459
                     /locus_tag="VIA51_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEQ8683345.1"
                     /translation="MKKKKNSFLRLLKMSLLSSLAGGIIGGMVGAFLGYHGGRLDHLT
                     FLKDDVINLIILLNRLVVVTDLTLSFVFLTQLKKETAVYNTIEEDDISENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            7478..8173
                     /locus_tag="VIA51_001407"
     CDS             7478..8173
                     /locus_tag="VIA51_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8683346.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTSIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(8265..9421)
                     /locus_tag="VIA51_001408"
                     /pseudo
     CDS             complement(8265..9421)
                     /locus_tag="VIA51_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(9559..10872)
                     /locus_tag="VIA51_001409"
     CDS             complement(9559..10872)
                     /locus_tag="VIA51_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEQ8683347.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(10847..11806)
                     /gene="nrdF"
                     /locus_tag="VIA51_001410"
     CDS             complement(10847..11806)
                     /gene="nrdF"
                     /locus_tag="VIA51_001410"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8683348.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(12139..14298)
                     /gene="nrdE"
                     /locus_tag="VIA51_001411"
     CDS             complement(12139..14298)
                     /gene="nrdE"
                     /locus_tag="VIA51_001411"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8683349.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFSAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKDLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(14318..14536)
                     /locus_tag="VIA51_001412"
     CDS             complement(14318..14536)
                     /locus_tag="VIA51_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEQ8683350.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
BASE COUNT         4568 a         2551 c         2986 g         4466 t
ORIGIN      
        1 taaacgttcg tataataaaa aaggagtttt tcatggaaaa aacaaaacgt tatatcattg
       61 caacagcagg gatacttctc cacttaatgt tgggatcgac ctatgcttgg agtgtttatc
      121 gtaatccaat tttacaagag accggttggg accaagctcc tgtcgctttt gccttttctt
      181 tagctatttt ttgtttaggt ttatctgctg cttttatggg aaatttagtt gaacaatatg
      241 gtcctcgtct aaccggaacg gtgtcagcta ttctttatgc ttctggaaat atgctgactg
      301 gtttagcgat tgatcgtaaa gaaatttggc ttttatatat tggttatggt gttattggtg
      361 gcttaggact tggagcggga tatatcacac cgatatcaac tattataaaa tggtttccag
      421 ataaaagagg catggcaaca gggtttgcta ttatggggtt tggttttgcg tctttattaa
      481 caagtccgat tgcccagtgg ctaattgaaa cagaaggttt ggtagcaaca ttttaccttt
      541 tagggctgat ttatctaata gttatgcttt ttgcttctca attgataata aaaccaactg
      601 ctgctgagat agctatacta gataaaaaaa gattacaaaa taacagttat ttaatcgaag
      661 gaatgaccgc taaagaagca cttaaaacaa aatcatttta ttgtctttgg gtaattttat
      721 ttatcaatat cacatgtggc ttaggactta tctcagttgt tgcgccaatg gcacaagatc
      781 taactggtat gagtccagaa atgtcagcaa ttgtggttgg tgctatgggg atttttaacg
      841 gtttcggtcg tttagtgtgg gctagtttgt cagactatat tggacgccgt gtgacagtaa
      901 tacttttatt tttagtaagc ataattatga ctattagttt aatatttgca catagttccc
      961 taattttcat gataagcatt gccaccctta tgacttgtta tggtgcgggt ttttctctca
     1021 ttccgcctta tttaagtgat ctttttgggg caaaggaact ggctacatta catgggtata
     1081 tattgacagc ttgggcaata gctgcattaa ctggacctat gttattatct atcactgttg
     1141 aatggactca taattatctt cttaccttat gtgtttttat tgtcttatac attttaggat
     1201 taatggtagc attaaggtta aagaaatgat gtcctataaa aaatttaaaa gtaaacccta
     1261 gcaaagccta gggttttttt atataattag gtttatggtt aaatcataca gtaaaacagc
     1321 aaatcataat atgcgtcgtc ctgttgtcaa agaagagctt gttcattata tgcgaacacg
     1381 gcagaagcaa accacaggtt ttttagcaga gttagagcaa ttcgcaagac aagaaaacat
     1441 tcctattatt cagcctgagg tcgtggctta tttcaggttt ttattgcaaa gcttacagcc
     1501 aaaacacatt ttggagattg gcacagccat tggtttttct gcgcttttaa tggctgaaaa
     1561 tgcaccagat gcgacgattg tgactattga tcgtaatcga gagatgatcg attttgctaa
     1621 agcaaatttt gctaagtacg acagtcgcca acagatccgc ctgttagaag gagatgcagc
     1681 agatatatta tctacacttg aaggaaattt tgactttgtg tttatggatt ccgccaaatc
     1741 caaatatatt gtctttctac cagagatttt aagactgcta aaagtcggtg gtgtagtcat
     1801 tttggatgat gtctttcaag gaggtgacat tacaaaaccg atcgaagata ttcgacgagg
     1861 tcagcgtact atttatcgtg gcttacagtc tttgtttgat gccaccttaa ctcatccaaa
     1921 cctaacaact agcctggtcc ctcttagtga tggattatta atgattcgta aaaatcaagc
     1981 agatattgta ttaccagatt aagtaacatt gataaattta tgttataata aattagttaa
     2041 agataaaaag gagctcagaa gtaaatgaaa aactcaaata aactcattgc tagtgttgtg
     2101 acattggcct cagtgatggc tttagcagct tgtcaatcaa ctaatgacaa tactaaggtt
     2161 atttcgatga aaggtgatac aattagcgtt agtgattttt acaatgaaac aaaaaacaca
     2221 gaagtatcgc aaaaagcgat gctaaatctg gtaattagtc gtgtttttga agctcaatat
     2281 ggtgataagg tttcaaaaaa agaagttgaa aaggcgtatc ataaaacagc tgaacagtat
     2341 ggcgcttcat tctctgctgc tttggcacaa tcaagcttga cacctgagac ttttaagcgt
     2401 cagatccgct cttcaaaatt agtagaatat gcggttaaag aagcagctaa aaaagaattg
     2461 acaacacaag aatataagaa agcatatgaa tcttatactc caacaatggc agtcgaaatg
     2521 attactttag ataatgaaga gacagctaaa tcagtcttag aggaactaaa agccgaaggc
     2581 gcagacttta cagctattgc taaagaaaaa acaacaacac ctgagaaaaa agtgacctat
     2641 aaatttgatt caggtgcgac aaatgtaccg actgatgtcg taaaagcggc ttcaagtttg
     2701 aatgagggtg gcatatcaga cgttatctcg gttttagatc caacttctta tcaaaagaag
     2761 ttttacattg ttaaggtgac taaaaaagca gaaaaaaaat cagattggca agaatataag
     2821 aaacgtttga aagctatcat tatagctgaa aaatcaaaag atatgaattt ccaaaacaag
     2881 gttattgcaa atgcattgga taaagctaat gtaaaaatta aagacaaagc ttttgctaat
     2941 attttggcgc aatatgcaaa tcttggtcaa aaaactaaag ctgcaagtga aagttcaaca
     3001 accagcgaat catcaaaagc tgcagaagag aacccatcag aatcagagca aacacagaca
     3061 tcatcagctg aagaaccaac tgagactgag gctcagacgc aagagccagc tgcacaataa
     3121 gtaggatttt attgactaat cagttaaaaa aacttataat aatttagtta agaattgttt
     3181 atcaaggatt agatacagaa aagtgacggt tgctgcgagt cattgataat tagataaaca
     3241 tgctacttaa ctttacaaca attgatatcg taaattaaga atgacaagtt cattgaatag
     3301 aggtggtacc gcggttttcg ccctctgtga gatggacttg ttttgtattg aggactattt
     3361 gaaatcaacg aaaggaatag agtagactag gctgccaggc ttatagctga tctcctagca
     3421 agaaagaaga gctgtgtcaa ctggtgtgat tacattacta gcttcagcat aacactgttt
     3481 ttcttactct ttgtatctaa atttttatga aagaattatc gtctgcacaa atccgccaaa
     3541 tgtggttgga tttctggaaa tctaaaggac attgcgttga gccttcagct aacttggttc
     3601 ctgtgaacga cccaacgctt ctttggatca actcaggtgt tgcaaccttg aaaaaatatt
     3661 ttgatggttc agtgattcca gaaaatccac gtattaccaa tgcacaaaaa tcaattcgta
     3721 ctaatgatat tgaaaatgtt ggtaaaacag cacgtcacca tactatgttt gaaatgcttg
     3781 gtaacttctc aattggagac tatttccgtg atgaagctat tgagtgggga tttgaactct
     3841 tgacaagtcc agactggttt gatttcccta aagacaagct ctacatgact tattacccag
     3901 atgacaagga ttcgtataac cgttggattg cttgtggcgt tgaaccaagt cacttggtgc
     3961 cgatcgagga taacttctgg gaaatcggtg ctggtccttc aggtccagat acggagattt
     4021 tcttcgaccg tggtgaagat ttcgatccag aaaatatcgg acttcgcctc ttggctgaag
     4081 atatcgaaaa cgatcgttac atcgaaatct ggaacatcgt tctctcacaa ttcaatgctg
     4141 acccagccgt accacgttca gaatacaaag aattaccaaa caaaaacatt gatacaggtg
     4201 ctggtcttga acgtcttgca gctgttatgc aaggggcaaa aacaaacttt gaaactgacc
     4261 tcttcatgcc aatcatccgt gaagtagaga agttgtcagg taaaacttac gatccagatg
     4321 gcgacaacat gagtttcaag gttatcgctg accacatccg tgcgctttca tttgctatcg
     4381 gtgatggtgc gcttcctgga aatgaaggtc gtggttacgt tcttcgtcgt cttctccgtc
     4441 gtgcggttat gcacggtcgc cgtcttggca tcaacgaaac tttcctttac aaattggttc
     4501 cgactgttgg acaaatcatg gaaagctact acccagaagt gcttgaaaaa cgtgatttta
     4561 tcgagaaaat cgttaaacgt gaggaagaaa catttgctcg tactatcgat gcaggtagcg
     4621 gtcacttaga ttcattgctt gcgcagctta aggctgaagg taaggatact cttgaaggta
     4681 aagatatctt caaactttat gatacttatg gattcccggt tgaattgaca gaggaattgg
     4741 cagaagatgc aggctacaag attgaccacg aaggctttaa gtcagccatg aaagaacaac
     4801 aagaccgtgc gcgtgcagct gttgttaagg gtggttcaat ggggatgcaa aatgaaaccc
     4861 tagctggtat tgttgaagaa tcacgattcg aatacgacac atatagtctt gaatcaagtc
     4921 tttcagtcat catcgctgat aatgaacgta ccgaagctgt ttcagaaggt caagcccttc
     4981 ttgtctttgc tcaaacacca ttctatgctg aaatgggtgg acaggttgct gacacaggta
     5041 gaatcaaaaa tgataagggt gacacagttg ctgaggttgt tgatgttcaa aaagcaccaa
     5101 atggtcaacc tctacacact gtaaacgttt tagcatcact ttcagttgga acaaactaca
     5161 cacttgaaat caacaaagag cgtcgtttgg ctgttgagaa aaaccacaca gctactcact
     5221 tgctccatgc agctcttcac aatgttatcg gtgaacacgc aactcaggct ggttcattga
     5281 acgaagaaga attcttgcgc tttgatttta ctcactttga agcagtaagc aatgaggaac
     5341 ttcgtcacat tgaacaagaa gttaatgagc aaatttggaa cgctcttaca atcacaacga
     5401 ctgaaactga cgttgaaacc gcaaaagaga tgggagcaat ggcgcttttt ggtgagaaat
     5461 atggtaaagt ggttcgtgtg gttcaaattg gtaattattc tgttgaactt tgtggtggaa
     5521 ctcacttaaa taattcttca gaaatcggtc tcttcaagat tgtcaaagaa gaaggtattg
     5581 gttcaggcac tcgtcgtatt attgcagtta ctggtagaca agcttttgaa gcttatcgta
     5641 accaagagga tgccctaaaa gagatcgctg ctactgtaaa agctccgcaa ttgaaagatg
     5701 cagcagctaa agtacaagct cttagcgact cgcttcgtga tcttcaaaaa gaaaatgcag
     5761 aacttaaaga aaaagcagca gctgcagcag ctggtgatgt ctttaaagat gttcaagaag
     5821 ctaagggcgt gcgcttcatt gctagtcaag ttgatgttgc agatgcaggg gcacttcgta
     5881 catttgctga taactggaaa caaaaagact actctgatgt gcttgttctc gtagcagcta
     5941 ttggtgagaa ggttaatgtc cttgttgcaa gcaaaaccaa agatgtccac gctggtaaca
     6001 tgatcaaaga attggcacca attgtagcag gtcgtggtgg aggtaaacca gacatggcta
     6061 tggcaggtgg tagcgatgca agtaaaattg cagagctgct agcagcagtt gctgaaatag
     6121 tgtaaatcca taaaaaacca agttatttag aacttggttt tttatatttg aaatgactac
     6181 catcataacc tttttgacta ttatcgttgt caaaaagaaa aagatatgtt acaattatag
     6241 taacaaatag acatgaggag gtgttagaga aaatgacaca tggtatcaaa cttaagaggc
     6301 agatttgctt atgggcaagt atcctgactc ttttcatttt aagttatcat cttatcaggg
     6361 taatctggtt tggagtaccc ttgagttatc tggttttggg ctttacagga ctagccttgc
     6421 tgttgaatac tttttcttat tttagaaagt aagttataag ttaaaggaga atgaaggaga
     6481 tggcaatgga ggttattctt aaaaatcggc tcaaagaatt acgagctaga gatggaatta
     6541 atcaaacgga aatggctaaa ctggcaggag tatcgaggca gaccatcagt ctcattgagc
     6601 gtaacgagta caccccatca gttataattg ccatgaaaat tgcaaaggta tttcaggaac
     6661 cagttgaaga ggtgtttcgt ctagtggagg tcgaggaatg aaaaagaaga agaatagttt
     6721 tttacgcttg ttaaaaatgt cattgctatc aagtttggcg ggagggatta taggtggcat
     6781 ggttggagcc tttttaggtt accatggagg gagattagat catctcacgt tcctaaaaga
     6841 tgatgtgatt aacctgatta tcttattaaa tcgtctagta gttgtcacag acctcacact
     6901 ttcttttgtt tttttaacgc aactgaaaaa agagacagct gtttataaca caattgaaga
     6961 ggatgatatt tctgaaaatg gttaccgtca gctgaataaa aagcatgctt ataccatgtt
     7021 attgattgcc gtagcttcta ttttatccat gtgcaatgtg ctacttggtc tgaccttaac
     7081 taatgattca cagcatgcca tgctggccat tccgcttctg gatatccttt tattattaat
     7141 ggtcattcct tttcaagctt tagccatgaa acgttacaat gccattcggg gaaccgatgt
     7201 tccttatttt ccaaatttga aagaattaaa acataatatc atggctctag atgaggcaga
     7261 gttacaagcc tatcataaga catcgtttga aagtgtgttg tcattaaatg gagtcatcat
     7321 cccttccttg tatgtgattt tattttttgt ctatctattc actggtcaag tggagttaac
     7381 agccatctta gttttggtgt taattcagct ctatttactc gttaagagtg caacaatgac
     7441 cagacaattt taccgttagc ctaaaaggag actgtttatg aaaggattca ttaattattt
     7501 aaaaatagca gtgctcatta ttctggctat ggttttcaat gtccttccga tgattttatt
     7561 gcaaaagcaa cacgatattc ctatggtact taattgggga attggtattt tctacttggt
     7621 tattgttgga agtgtcctta ttgtattatg gcgtctttat caagctaagc aagacacctc
     7681 tattaaacag caaaaaatga gattggttga ctggggttat ttagcattat tttggttaat
     7741 catccgtgtg atagctattg taggtaccct tgttaaccag ctatggtctg gtcaacaagt
     7801 gagtgctaat gatgctgcaa tacatacctt agctagactt atcaaaggtg gtttcccgct
     7861 ttatactgcc ctatttgtac ttgtgatagc ttttatcgct cctattatgg aagaactagt
     7921 ctttagagga tttcctatga ttgatctctt caaaggaaaa tcacttaagg tggcaggttt
     7981 agtgacctct cttgtttttg ctttaccaca tgccaccaat agtgttgaat ttatcatgta
     8041 cagctgtatg ggcatttttc tctttgttgc ctatcaaaga cgaggaaact taaaagatgc
     8101 tatcttgtta catattttta ataacttgat tgaagtcatt ttgttaatgt caataggctt
     8161 aggagtcata taataaaaag cttcggatgg atgaactgca ccccaaaagt tggacaaaaa
     8221 aactaacatt tggttggact tgtcaagaaa aaatagacat aaagttaagc taatgagtaa
     8281 ctattttttt caaattcaac aggtgagaga taccctaaag ctgaatgcag acgtttgggg
     8341 ttatagtaag tctcactata tttaaaaatc tcaagctgag cttgcttaat agttgcgaaa
     8401 tgagcatcat tgacaagctc tctttttaat gttttataaa aggattccat gagtgcatta
     8461 tcgtatggat taccttttcg attcatactg gacttacatt ttttctgtct aagtaggtcc
     8521 tgaaatcatg ctccggtata ttgagaaccc tgatctgtat ggacgattac cccttcttta
     8581 ggcttttctc tattataagc ttgattgaaa gcttctgtta ccaacttgtc ttgcatacgt
     8641 tagcccattg cccaaccaac aacctttcta ctataaacgt ctatcaagac agacacataa
     8701 agtattcctt cttgtgtagg aatgtaggtt aggtctccta gccataattt attcttacca
     8761 gtcgcttgga aacattgatt aacaagattg ggacgagttc atgaagaacg tcgacggtta
     8821 tagtatttat attgatatcg acttccttta gcatagagac ctagctgatg aaggagtcta
     8881 ccaacacgtt tataattgac atggatgcca cgtctacaaa gttcttgggt aattcgtaca
     8941 cttccgtaac gctctttatg ttcatagaaa atggctttaa tcatttcctt taaagcttca
     9001 ttctcaacat gccttgaaga gggacgacgt tttaaataag catagaaacc tgaacgggag
     9061 acttgaagag tttgacaggt gtgatgacta ttcaagctaa cactattttc cttcagaagc
     9121 tgaaatttta tttccggttt ggcttcaaaa agacctggaa cttttttaga agagctaatt
     9181 cctcctgtag cagtttgtgc tctttttcaa gtttttttgt cttaaattga gcatgacgaa
     9241 gtgcgctccc atgtcctggg aacgcacttt ctccatattt ttcatattct tgaatccatt
     9301 gataaagact attgggatga atttctaaag ttgaactaac catttttaca ggctgctctt
     9361 cctcaaggat gagttttaca gcagagagtt tgaaggcttt atcaaaggtt tttcttggca
     9421 taatgacttt tcctcgtttc cacttaattt tgtgtctact ttattatacc aagtccaact
     9481 ttgcttaaaa tataatgtcc aacttttggg gtgcagttca ttcatccgaa gctttttatt
     9541 aaaaaagtaa ttaactaatc atttaaggat gaaacgataa aactgatagc taaaataaaa
     9601 aatgaggtta gctaatgcta aagggataat cattagtaac gattggcctg taatttcaac
     9661 cagaaaaact ggtgccgcca agggtatctt attgatcaca cctaaaaaga ttgttgcacc
     9721 aaccataatg gctaacgtat ttgatagaga caagggaata aggtactgac taaggatagc
     9781 tagtagtaag ccactagcac ctccaagcat catagaagga gcaattttac ccccttttgc
     9841 tccagaagca aaaactaaag agatagcgac agctttggca acaagtagcc agctaatata
     9901 gctcagatgt ggttcttcat ggagaaaaaa gagtaatcca gctttgccat ttcctaaaat
     9961 ctctgggaag aaaatgctga gtcctgcgat aaggctaaaa gcgatgagaa ctttcggaat
    10021 aaaccactga cttttggcat cagccttagg aaggtgtttc aaaagatgtt tgtaagcgtg
    10081 agcaaagagg gaaaggataa gaccagccag gacggaccca ataagggttc ctagcgtcca
    10141 atgttgctga ggcattaggt attgaatctc atgtcggcct tgtaataaag caactgtttc
    10201 cacagccaca tagctcgtta ggcaggcagc gtatatattt ttaagggacc aacggttaag
    10261 aatagcttct aagataaata aaatagtggc taagggagca ttgtagacag caccaagggc
    10321 agcgccagaa gcgcaggcta ataaaagttt ttgatcggct tttgacaagt tgcatctttg
    10381 gctccaaaga gacgtcaagg taacagcgac ttcccgtgaa gctccttctc ggccgacagg
    10441 agctcccata gatacggtcg ttaattggag ccaaccatgc caaaactgtg tccagggact
    10501 aaatgagatg tcatcttgaa tgatttgctg aatagattga atgtcctttc cttttttagc
    10561 caataggtgc cacccaagac ctgcaagaag tccagcaaag aggagtgaaa gagctcgtct
    10621 ttgtggtgga acactagcaa tcatagtgct aaaagaacct tgactgaatc caaaactgag
    10681 ggactgaatc aggtgaatgg cttttgttaa gataaaagca acaaggccag ctgttaaacc
    10741 tgttaaaaag aggtaaaagg tcaagagtaa aaagtgtcgt ttcataagac tattataaca
    10801 aaagttaaga aaagagactg atagattatc agtctcgtga gcactattag agtccataat
    10861 tataatcgtc atcagacata gcttctacag aaccaagaag atagccattc cctacctgtg
    10921 agaaaaagtc atggtttgat gttcctgttg aaataccatt cataacaatt gggttaacat
    10981 cgtttgcagt atctgggaat aaaggatctt gtcctaaatt cataagagct ttgttagcat
    11041 tgtagcgtaa aaaggtcata acttcctcag tccaccctac gccatcataa agcgttttgg
    11101 tgtatttttc ttcattttca tacagctgat aaaggaggtc atacatccaa tcacgaaaat
    11161 tctcttgctc atcttctggt agttcgttaa aaccaagctg gaatttgtaa ccgatataag
    11221 taccatgtac agattcatca cgaataatta gtttaatgat ttcagcaaca tttgctagct
    11281 tattatttcc caaatagtaa agaggggtga aaaagccaga ataaaaaagg aaagtttcga
    11341 gatatgttga ggcaactttc ttttgtaagg catctccatt agcgtaaatg tcattgataa
    11401 tacgtgcttt ttcttgaaga aactcattat tattagtcca ctcaaagatc tcttcaattt
    11461 cttttttggt gtttaaggtt gaaaagatag acgaataaga tttagcgtga acagattcca
    11521 tgaattgaat attgtttaag acagcttctt cgtgaggagt gcgaacatca gcacgaatag
    11581 cttcgacacc agtttctgat tgcatggtat caagtagggt taatcctcca aaaaccttgc
    11641 caacaagatc tttttcttga agagaaagtt tgcgccaatc gtctaagtca tttgataaag
    11701 ggatacgggt atcaagccaa aattgttcgg tcaacttttc ccaagttgac ttgtcaatga
    11761 cgtcttcgat ttcattccag ttaattgctt cataatatgt agtcatagaa aaatgatctc
    11821 ctaaagagta gtaaagtgcg ttaaggatat cgagataaac cagtagaacc gaccaaagtt
    11881 ctaccggtaa taataagttt aaatagattc aaaagggtaa cgaatgagtt agtgagtggt
    11941 ttaggcagat cgcctaaagc gattgcccaa gaagtaatag atgttttagc atcattaggg
    12001 catatcgagg aattacgaca cggagtaagg aaagtcgata atactttcct tacgtagtta
    12061 gtgagtggtt taggcagatc gcctaaagcg actgccgtag aagtaataga tgctttagca
    12121 tcattacttc ttaaccaatt aaatgacaca agattcacat tggtttgcgc ccacttcttc
    12181 cccatcatcc gtaaaggtac ggatatagta gatagattta atgcctttat tgaaagcgta
    12241 gtttcgtaag atggataaat cacgagtggt ttgtttgctt tgtgttttcc actcataaag
    12301 ctccataggc aactcactac gaaggaatag agttaatgac aagccttggt ccacatgttc
    12361 ggtcgcagcg gcatagacat caataacttt gcgcatgtcc atatcgtaag cagatgtata
    12421 gtaaggaatg gtatccgtag acaaaccatt tgcaggatag tagattttac caattttctt
    12481 ttcttgacgc tcttcgatgc gttgtgtgat tgggtgaata gaagcagagc agtcattgat
    12541 ataagaaata gagccatttg gagcaactgc tagtcggttt tgatgataaa gaccatcttt
    12601 ttgaacggcg tcgcgaagag cctcccaatc tgaagcttgc ggaataaaat ggtctttgaa
    12661 cagatctttc accaaatcag attttggaac aaagtgtcct gtaacgtatt tatcaaagta
    12721 actaccatta gcgtacttag agttctcaaa gccaacaaag gtagtttggc gctcacgagc
    12781 gatgttattg gattcgacca aggtccaata attcaggagc ataaagtaaa tatcagtaaa
    12841 ctcgatggat tctggactgc catattcaat atgatgttga gcaaggtaag aatgtagtcc
    12901 catagctcca aggccaaaag tatgagcttg gctattgcca tgtttaatgg ttggaacagc
    12961 ttcaatgctt gatgaatcag taacaaaagt tagggcacgt gtcatggtct taatagaacg
    13021 gccaaagtct ggtgaggtca tcatgttcag gatattagtg gaacctaagt tacatgaaat
    13081 atcagttccc atttctacaa actcttgcgc atcattgata aggctaggtg tttgaacttg
    13141 taaaatttca gaacacaagt tgctcatgat gatttttcca tcgataggat tagctttatt
    13201 agctgtatca atattgatga tataagggta accagattct tgttgtaatt ttgaaatctc
    13261 tgtttcaaga tcacgagctt taattttagt cttagtaatt ttagggttcg ccactaactc
    13321 atcgtacata ttggtaatgt cgagatagtt aaagggaatg ccatattctt tttcaacatt
    13381 gtaaggacta aagagataca tgtcctcgtt tttacgagct aattcgtaga atttatcagg
    13441 aacggtaatc cctagtgaca aggttttaac acgcaccttt tcatcggcat tttctttttt
    13501 agtagataag aaagcaatga tatcaggatg aaaaacattt aggtaaacaa caccagctcc
    13561 ttgacgttgc ccaagttgat ttgaataaga aaaactatct tcaaataatt tcataacagg
    13621 aacaactcct gaggctgcac cagcatagcc tttgattggt gcgccagctt cacggaggtt
    13681 agacaaggta atcccaactc ctccaccaat acgggataat tgcaaagcag agttgataga
    13741 acgtccgata gagttcatgt catcagttac ttgaatcaag aaacaagaga ccaattcacc
    13801 acgacggctt cgaccagcat ttaaaaagga aggagtagcc ggttggtaac gttggttaat
    13861 catttcaacg gctaaatctt ttgctaagtc ttcttgacca tctgcaaaat acaaagcatt
    13921 aaacaagaca cggtcttcaa ggttttctaa ataatgctct ccatcatttg tttttaaggc
    13981 gtattgctgg tagaacttgt aggctgccat aaatgattta aagcgaaaat tttctgattt
    14041 gattatgcta tctaattcag taataaattc agggcggtat ttctgaataa aagctgattc
    14101 aatgtaatca tttgagatta aatactcaat tttttccgta atggaagtaa aagacatggt
    14161 gtttggcagc acattttcag cggaaaaagc ttttaaagct tctttgtctt tatgaagtgg
    14221 aattttacca ttaacaggac ggttaatttc attatttagg cgaaaatatg aaatatcgcc
    14281 aagatctttg agactcatat tatttttcct tgtcttatta aatcaattct tttaactttg
    14341 caggttggaa gccagaaaat acgaggttat ctgcttcgat aacaggagca gatgtgaagc
    14401 caagactttt cacataatcc actttttcag gatgttcatc gatattaatt tcctggaagt
    14461 tggctccgtg ttgttctaaa aatttcttag tcattttgca ctgcatgcaa ttatttttgg
    14521 aatatactgt aatcatgtct tgtccttcta aaattagtaa tggttccatc t
//
LOCUS       DAUGQX010000043        14556 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUGQX010000043 DAUGQX010000000
VERSION     DAUGQX010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14556
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.043"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            42..746
                     /locus_tag="VIA51_001413"
     CDS             42..746
                     /locus_tag="VIA51_001413"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEQ8683351.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVTAGSFSK
                     RFGVEEGHVLETPIVEFYYKNDDLDDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            870..4595
                     /locus_tag="VIA51_001414"
     CDS             870..4595
                     /locus_tag="VIA51_001414"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEQ8683352.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIEALPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYQADDFATYKAEQGLAMEVDDLLFIQNYFKSIGCVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPNDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKDNFSQFEAIQAQHKIT
                     AASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKLVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQILFASAVKYFTGK"
     gene            4756..6210
                     /locus_tag="VIA51_001415"
     CDS             4756..6210
                     /locus_tag="VIA51_001415"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEQ8683353.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDRGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHSVDEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6238..7260
                     /locus_tag="VIA51_001416"
     CDS             6238..7260
                     /locus_tag="VIA51_001416"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEQ8683354.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYIATGKNNPVKLEEVVSGVAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAV
                     GVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVKAALPLIKEELVKGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     ASVVIK"
     gene            7428..7982
                     /gene="purN"
                     /locus_tag="VIA51_001417"
     CDS             7428..7982
                     /gene="purN"
                     /locus_tag="VIA51_001417"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEQ8683355.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKVAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYERRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8166..9713
                     /gene="purH"
                     /locus_tag="VIA51_001418"
     CDS             8166..9713
                     /gene="purH"
                     /locus_tag="VIA51_001418"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEQ8683356.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVTLDDAGV
                     ETIAIDDVTRFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYTYKADPVSIFGGIIVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9771..10895)
                     /locus_tag="VIA51_001419"
     CDS             complement(9771..10895)
                     /locus_tag="VIA51_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ8683357.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFIVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            11148..12413
                     /gene="purD"
                     /locus_tag="VIA51_001420"
     CDS             11148..12413
                     /gene="purD"
                     /locus_tag="VIA51_001420"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEQ8683358.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFANGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVEMIVRPVLEGMVAEGRPYLGVLYVGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPFDYEKGVPLPEKTDGDIITYYAGVKFSENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            12691..13182
                     /gene="purE"
                     /locus_tag="VIA51_001421"
     CDS             12691..13182
                     /gene="purE"
                     /locus_tag="VIA51_001421"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEQ8683359.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDLLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            13169..14242
                     /gene="purK"
                     /locus_tag="VIA51_001422"
     CDS             13169..14242
                     /gene="purK"
                     /locus_tag="VIA51_001422"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEQ8683360.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASDSPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IVEKDFLANKAGVTVAPYKVVTSSLDLGGLDLTKTYVLKTETGGYDGHGQKIIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGKDVTVFPVQENIHRNNILSKTIVPA
                     RISDQLADKAKKTAVQIAKKLQLSGTLCVEMFTTADDIIVNEIAPRPHNSGRYSIEAC
                     DFSQFDTHILGVLGAPLPQIQLHAPAVMLNVLGQHVQQATDYVAKNPSAHLHMYGKLE
                     AKHNRKMGHVTVFAKDADEVKEF"
     gene            14269..>14556
                     /locus_tag="VIA51_001423"
     CDS             14269..>14556
                     /locus_tag="VIA51_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HEQ8683361.1"
                     /translation="MANIQINRIKSKLTELFSSIIYMGNIKVDEDSEEYKKMWYSRAY
                     SAYSTFLLGAENVDEATKSVTDGFADNGIDAIYNDKNKKILYFIQTKFSNEA"
BASE COUNT         4152 a         2877 c         3416 g         4111 t
ORIGIN      
        1 gttactctta aatgaaaaca gaaagaaagg cgaataatca agtgactaac cagcttattt
       61 ataaaggaaa agcgaaagat atttatagta caaaagatga aaatgtgatt agaacggtct
      121 ataaagacca agctactatg ttgaatggag ctcgtaagga gactattgat ggcaagggag
      181 cactaaataa tcagatttca tctcttattt ttgagaaatt aaataaggct ggtgtggtga
      241 cacattatat tgagcaaatt tcaaaaaacg aacaattgaa taaaaaagtt gatattattc
      301 cacttgaggt ggtgttacgg aatgtgacag caggctcatt ttcaaaacgt tttggagtgg
      361 aagaaggaca tgttcttgaa acgccaattg tggaatttta ctacaaaaat gatgatctgg
      421 atgatccttt tatcaatgat gagcatgtga agtttttggg tattgttaat gatgaggaga
      481 ttgcttatct gaaaggagag actcgccgta ttaatgaact cttgaaaggt tggtttgctc
      541 agattgggct taacttgatt gacttcaagt tggagttcgg atttgatcaa gaaggtacaa
      601 ttatcttagc agatgaattt tcgcctgata actgtcgcct atgggataag aatggtaacc
      661 atatggacaa ggatgttttt agaagagacc ttggcaacct gacggatgtc tatcaagttg
      721 tacttgagaa gttgatagca ttgtaactag aagaggaagg aattgaatcc gttcgggaaa
      781 ctccgaaaaa aagatggaac ttactgaaat ctcaatttca gatgtcctcc tattttccag
      841 tcgctccctt gtcggacttg gtatcttata tgaataaacg tatttttgtt gagaaaaagg
      901 ctgactttgg tattaaatcg gctagtcttg tgaaagagtt gacgcataat ctacaactga
      961 cctctttgaa ggctttgcgt attgtgcagg tctatgatgt cttcaatttg gctgaggatt
     1021 tgctggcgcg tgctgagaag catattttct ctgagcaggt gacagactgt cttttgacgg
     1081 aaactgaaat cactgcggag cttgataagg ttgccttctt tgccattgag gcgcttcctg
     1141 gtcaatttga ccaacgtgct gctagttcgc aagaagcttt gctattattt ggaagtgaca
     1201 gtcaggttaa ggtcaataca gcccagctat acttggtcaa taaggatatt acagaagcag
     1261 agcttgaagc cgttaagaac tatcttttga accctgttga ttcgcgtttc aaggacatta
     1321 ctttgccgct tgaagagcag gctttctctg tatctgataa gacgatccct aatcttgatt
     1381 tctttgaaac ttatcaagct gacgattttg cgacttataa ggcagagcag ggcttggcta
     1441 tggaggtcga tgaccttctc ttcatccaaa attatttcaa atcaatcgga tgtgtgccaa
     1501 ctgagactga gttgaaagtt ttggatactt actggtcaga ccactgccgt cacacaacct
     1561 ttgaaactga attgaagaac attgattttt cagcttctaa attccaaaaa caattgcaga
     1621 caacttatga caaatatatc gccatgcgtg atgagcttgg tcgttctgaa aagccacaaa
     1681 cacttatgga tatggcgact atttttggtc gttatgagcg tgccaacggt cgtctggacg
     1741 atatggaagt ctcagatgaa atcaatgcct gctcagttga gattgaagta gatgttgatg
     1801 gtgtgaaaga gccttggctc ctcatgttta agaacgagac tcacaatcac ccaacagaaa
     1861 ttgagccatt cggtggagcg gcgacttgta tcggtggtgc tattcgtgac ccattgtcag
     1921 gacgttcata cgtttatcag gctatgcgta tttcaggcgc aggcgatatc acgactccga
     1981 ttgcggaaac acgtgctggt aaattgccac aacaagttat ttctaaaact gcggcgcacg
     2041 gctattcttc atatggtaac caaattgggc ttgcgacaac ttatgtgcgc gagtacttcc
     2101 accctggctt cgtagccaaa cgtatggagc ttggagctgt ggttggtgct gcacctaagg
     2161 aaaatgtggt tcgtgaaaaa ccagaagcag gcgatgtggt catcttgctc ggtggtaaaa
     2221 caggtcgtga tggtgtcggt ggtgcgacag gttcatctaa ggttcaaacg gttgaatctg
     2281 tggaaacagc tggcgcagag gtacaaaaag ggaatgccat tgaagaacgt aagattcaac
     2341 gtcttttccg tgatggcaat gtcactcgtc ttattaagaa atcaaatgac ttcggtgcag
     2401 gtggtgtctg tgttgccatc ggtgaattgg ctgacggtct tgaaatcgat ttggacaagg
     2461 tgcctcttaa ataccaaggt cttaatggta ctgaaattgc aatctcagaa tctcaagagc
     2521 gtatgtcagt cgttgttcgt ccaaatgatg tggatgcctt catcgcagcc tgcaacaagg
     2581 aaaatatcga tgcagtcgtt gttgcgaccg ttactgaaaa accaaatctt gtcatgactt
     2641 ggaatggcga aatcatcgtt gatttggaac gccgtttcct tgataccaat ggtgtccgtg
     2701 tcgttgttga tgctaaagtc gttgacaagg acttgacagt tccagaagca cgcacaacat
     2761 cagcagagac acttgaagca gatacgctta aggtcttgtc tgacctcaac cacgctagtc
     2821 aaaaaggtct tcaaactatc tttgactcat ctgttggtcg ttcaaccgtt aaccacccaa
     2881 tcggtggtcg ttaccaaatc acaccgacag aaagttctgt tcaaaaattg ccagttcaac
     2941 atggtgtgac aacaactgca tctgttatgg ctcaaggtta caatccttat attgcagagt
     3001 ggtcacctta tcacggtgct gcctatgctg tcattgaagc gacagctcgc ttggtagcaa
     3061 cgggtgctga ctggtctcgt gcacgtttct cttaccaaga gtactttgag cgtatggata
     3121 aacaggcaga gcgttttggt cagccagtat cagctcttct tggttctatt gaggctcaga
     3181 ttcaacttgg tttgccatca atcggcggta aggactctat gtctggtact ttcgaagact
     3241 tgacagtacc accaaccttg gtagctttcg gcgtgacaac agcggacagc cgcaaggttc
     3301 tctctcctga gtttaaagcg gctggcgaaa acatttacta tatcccaggt caagctattt
     3361 cagaagatat tgattttgac cttatcaagg ataactttag ccagtttgaa gctattcaag
     3421 ctcaacataa gattacagct gcctcagccg ctaaatacgg tggtgtccta gaaagtcttg
     3481 ctctcatgac ttttggtaac cgtatcggtg cttctgttga aattgcagag cttgacagca
     3541 gcttgacagc tcaactcgga ggttttgtct ttacatcagc tgaggaaatt gctgacgcgg
     3601 tgaaaatcgg tcaaactcag gcagacttta cagtcactgt caatggaaat gaccttgctg
     3661 gcgctagcct tctagcagcc ttcgaaggca aattggaaga ggtttaccca acagaatttg
     3721 agcagacaga tgttcttgaa gaagttcctg ctgtggtatc agatactgtt atcaaggcta
     3781 aggaaacaat tgaaaaacca gtggtttaca ttccagtctt ccctggtacc aactcagaat
     3841 acgattcagc taaggccttt gaacaggttg gagctagtgt caacttggta ccatttgtaa
     3901 ccttgaatga ggttgctatt gctgagtcag ttgacactat ggttgctaat attgctaagg
     3961 caaatatcat cttctttgct ggaggtttct cagcagcgga tgaaccagat gggtctgcta
     4021 agtttatcgt caatatcttg cttaacgaga aggtccgcgc agctattgac agcttcatcg
     4081 aaaaaggtgg ccttatcatc ggtatctgta atggtttcca agcccttgtt aaatcaggtc
     4141 ttcttccata cggaaacttc gaggaagctg gtgagacaag tccaactctc ttctataatg
     4201 atgctaatca gcatgttgcc aagatggttg agactcgtat cgcaaatacc aactcacctt
     4261 ggttggcagg agttgaggtc ggcgatattc atgccattcc agtttcacat ggtgaaggta
     4321 aacttgttgt cagcgcttct gaatttgcag agctaagaga caatggtcaa atctggagcc
     4381 aatatgtgga ctttgacgga caaccatcta tggattctaa atacaatcca aacggctctg
     4441 tcaatgccat cgaagggatt accagcaaga atggtcaaat catcggtaag atgggacact
     4501 cagaacgctg ggaagacgga ctcttccaaa atatccctgg taacaaagac caaatcctct
     4561 ttgcaagtgc tgtaaaatac tttacaggga agtaaaaagg ttcagtgaac ctttttagcc
     4621 ctcgccttga attagtgaag ggcgaggtta gaaagaatct cgcttaattt ttgagaaata
     4681 gtaaacacgg gcgataagtt gtgcgaaaaa ctttctattt tcgctttact tgacagcctt
     4741 tgtatcgagg taaaaatgac atacgaagta aaatctctaa atgaagaatg tggagtcttt
     4801 ggtatctggg gacatcctca ggcagctcaa gtcacttact ttgggcttca tagccttcaa
     4861 catcgcggtc aagaaggagc tggtattgtt tcaaatgaca atgggaaact ctatggttat
     4921 cgaaatgttg ggctcctttc tgaagttttt aagaatcaat ctgaattaga taatttaact
     4981 gggaatgcgg ctattggaca tgttcggtat gctactgcag gttctgcaga tattcgcaat
     5041 attcagcctt ttctttataa atttcatgac gggcaatttg ctttatgcca taatggtaat
     5101 ttgacaaatg ctatttcctt aaggaaagaa ttagaaaagc aaggtgcaat tttcaatgcc
     5161 tcctcagata ctgaaatttt gatgcacttg attcgtcgaa gccataactc aagtttcatg
     5221 ggaaaggtaa aagaagctct aaatacagta aagggtggct ttgcctatct actgatgaca
     5281 gaaaataaac tcattgctgc tcttgaccct aatgcctttc gtcctttgtc aattggacaa
     5341 atgcaaaatg gtgcctgggt tatttccagt gagacctgtg cttttgaggt ggtaggcgca
     5401 aaatgggtta gagatgttga acctggcgaa gttattctta tagacgatcg tggtattcaa
     5461 tgtgatcgtt atactgatga aacgcaactg gcaatttgtt cgatggaata tgtctatttt
     5521 gcaaggccgg attcaactat acatggtgtt aatgttcata cggctcgaaa aaatatggga
     5581 aagcgtcttg cacaagaatt taaacaggat gctgatattg taattggtgt cccaaattcg
     5641 tccttatcgg ctgctatggg ctttgctgaa gaatccggat taccaaatga gatgggtctt
     5701 gtaaaaaatc agtatacgca gcgaaccttt attcaaccga cacaagaatt aagggaacaa
     5761 ggtgttcgaa tgaaactatc agcggtatcc ggtgttgtca aaggaaagcg cgttgttatg
     5821 attgatgact caattgtaag aggaacgact tctagaagga ttgtcggatt attaagagaa
     5881 gcaggagcta gtgaagtaca tgttgctata gctagtccag aattaaagta tccttgtttt
     5941 tatggtattg atattcagac tcgtcgtgag ttgatttcag ccaatcactc tgttgatgaa
     6001 gtgtgtgata ttattggcgc agatagtctg acctatctct cactggatgg gttgattgaa
     6061 tcaattggac tcgaaacaaa agcaccaaat ggtggtttat gcgtagctta ctttgatggg
     6121 cattatccaa caccgcttta tgattatgaa gaagaatacc tcagaagttt agaagagaaa
     6181 acaagttttt atattcaaaa agtgaaataa gctctgctaa ttatataagg agaaaacatg
     6241 tctgaaaaaa atgcttatgc aaaatctggt gttgatgttg aagctggtta tgaagtggtt
     6301 gaaagaataa aaaaacacgt tgctcgtaca gaacgtgcgg gagtcatggg agctctaggt
     6361 ggctttggtg ggatgtttga cttgagtaaa acaggagtta aagagcctgt cttggtttca
     6421 gggactgacg gtgtcggaac aaaacttatg cttgctatca agtacgacaa gcacgacaca
     6481 atcggtcaag actgtgttgc catgtgtgtc aatgatatta ttgcagcagg tgctgagcca
     6541 ttatattttt tagattatat tgcgacagga aaaaataacc cagtcaaact tgaagaagtt
     6601 gtttctggtg ttgcagaagg ttgtgttcaa gcaggagcag cactcattgg aggtgagacc
     6661 gctgaaatgc ctggaatgta tggtcaagat gattatgacc ttgcaggctt tgctgttggt
     6721 gtggctgaaa aatctcaaat catcgacggt tcaaaagtaa aagaaggcga tattcttttg
     6781 ggacttgctt caagtggtat ccattcaaac ggttattctt tggtacgtcg tgtctttgct
     6841 gactatactg gtaaagagct gcttccagag cttgaaggca aacaacttaa ggatgtcctc
     6901 cttgagccaa ctcgtatcta tgttaaagca gctctgccat taatcaagga agaactagtc
     6961 aaaggtatcg gccacatcac gggtggtggc tttatcgaga atattcctcg tatgtttgcg
     7021 gatgatttgg ctgcggaaat cgatgaggac aaggtgccag tgcttccgat tttcaaggcg
     7081 cttgaaaaat atggtgacat caagcacgaa gaaatgtttg aaatcttcaa tatgggtgtc
     7141 ggtcttatgc tagctgttag tcctgaaaat gttaaccgcg tcaaagagct cttggatgaa
     7201 ccagtttatg aaatcggtcg tatcatcaag aaagcagacg ctagtgtggt gattaaataa
     7261 gtcactaaat tttataagaa aggagtgttt agttagtttg cctaactgaa cacgggatta
     7321 aatttctagg aaaaaagata aaatgactta gacgcaagcg tcgttgttcg ttttcctatt
     7381 tttctacgaa atttttcggc aagccgaatc atccctttgt atcgaatatg aaaatcgctg
     7441 tttttgcttc tggtaatggt tccaactttc aggtcatagc agagcagttt ccagttagtt
     7501 ttgtcttttc agatcatcgt gatgcctatg ttttagagcg tgctcagaat ttagccattc
     7561 caagcttcgc ttttgaactc aaggagtttg agaataaggt ggcttacgag caagccatcg
     7621 ttgatttgtt ggacaaacac gagattgact tagtctgtct ggcaggctat atgaagattg
     7681 ttggagaaac cttactcttg gcctatgaga ggcgtattat caatattcac ccagcctacc
     7741 tgcctgaatt tccaggtgcc cacggtatcg aggatgcttg ggaagctggt gttgaccagt
     7801 ctggcgtgac catccactgg gttgactctg gtgtggatac cggtcaggtc atccaacaag
     7861 tgcgcgtgcc acgcctagca gacgatagcc tagaaagctt tgaaacccgt atccatgaaa
     7921 ccgaatatca actctaccca gctgtcttag atagcttggg agtggagagg aaagtaatct
     7981 agcctttatc ttaaaatttt aggtaaagtt aggaaagata gtaaagaaga attaacgttc
     8041 caaaaagaaa ggaattgaac ccgtctggaa ggcacagaaa aaagataaac atctcctagg
     8101 cgcaagcgtc ttcgtcgagt ttcctatttt tccttggcct tctagtcgga cttggtatct
     8161 taaatatgac taaacgtgct ttaatctcag tgtctgacaa gtcaggaatt gttgactttg
     8221 caaaagaatt gaaaaacttg ggttgggata ttatctcaac tggtgggact aaggttaccc
     8281 ttgacgatgc tggtgttgag accattgcca tcgacgatgt gactagattc ccagagatga
     8341 tggacggtcg tgttaagacc ctccacccaa acattcacgg tgggcttttg gctcgtcgcg
     8401 acgctgacag ccaccttcag gctgctaagg acaacaatat cgagctgatt gacctcgtgg
     8461 ttgtcaacct ctatcccttc aaggagacta tccttcgtcc agacataacc tatgatttgg
     8521 cggtggaaaa catcgacatc ggcggtccat caatgcttcg ctcagccgct aaaaatcacg
     8581 ctagcgtgac cgttgtggtt gacccagcgg attatgcgac tgttttggga gaattggctg
     8641 acgctggtca gacgacattt gaaacgcgtc aacgcttggc agctaaggtc tttcgtcaca
     8701 cagcagccta cgacgctttg attgctgagt acttcacaac tcaagtggga gaggctaagc
     8761 ctgaaaaatt aaccatcact tacgacctta aacaggctat gcgttacgga gaaaatccac
     8821 aacaagacgc tgatttctat caaaaagcct tgccaacaga ctactcaatt gcttctgcta
     8881 aacagctcaa cggaaaagaa ttgtctttca ataatatccg tgatgccgat gcggcaatcc
     8941 gtattatccg cgatttcaaa gaccgtccaa ctgttgttgc tctcaaacac atgaacccat
     9001 gtggtatcgg acaggctgat gacattgaga ctgcttggga ttacacttat aaagctgacc
     9061 cagtttcaat ctttggcgga attattgtcc ttaaccgtga agttgacgca gcgacagcca
     9121 agaagatgca ccctatcttc ttggaaatca tcatcgcacc atcatactca gaagaagcgc
     9181 tagctattct cacaaataaa aagaaaaact tgcgaatcct tgagttgccg tttgatgccc
     9241 aagctgccag cgaagtggaa gctgagtaca ctggcgtagt tggtggactt ttggtgcaaa
     9301 accaagacgt tgtggctgaa aatccatctg actggcaagt ggtgacagac cgccaaccaa
     9361 cagaacaaga ggcgactgcc cttgagtttg cctggaaggc tatcaagtat gttaagtcta
     9421 acgggattat tattactaac gatcacatga cgcttggact cggtgcaggt caaaccaacc
     9481 gtgtcggctc agtcaagatt gctatcgagc aggctaaaga ccaccttgac ggtgccgttc
     9541 tagcatcaga tgccttcttc ccatttgcgg acaacattga agaaatcgct gccgcaggga
     9601 tcaaagcaat catccaacca ggtggttcag ttcgtgacca agactctatt gacgccgcaa
     9661 acaaacatgg cttgaccatg atcttcacag gtgtgagaca ttttaggcat taataaaaaa
     9721 atgtggtcta attaaaacca cattttttat taaaagaaaa tataagttaa ctataatttg
     9781 ttagctttat cagcatttac ccatgttcca cgagatccga tttgaacata aataccatta
     9841 cttggttgat caatttttaa tactttataa ctaccagtga cgataaaata ttcacccaca
     9901 cggagaattt gatctcctaa aacttttcct tggttatctg tttcatctaa tggtgtggga
     9961 tcaatccagt ttagtggagt tgggtctcct ccggctaatt ctttattaac gatcaaatta
    10021 ttaacaagct gatctacacg aaaaacgcca gggaaggtaa cagtatcacc gaccttaatg
    10081 gaaggttttg tattgtcatt ttgaaccaca gactgtgcgg gctctttaat gggaatatag
    10141 cgtcggtttc cagaaaaact gaggtagcta agccatgtat aacctccagc agtcacgact
    10201 ttatcgtaat aaacagattg acctgcttca tagtaagcaa gatcagggct atcgatactg
    10261 gtttgtcctt tgactggtaa tctggttgta aagtgataag ttccagaggg gtcaaatgaa
    10321 gcttgagaaa tgtgttttag ttgtcttggg taggaatgac ttgtctgaga tgataagtct
    10381 ttaaaatgga tataaccact tacctgagat tttggaattt gacgcttatg gtatctttca
    10441 gggccttgtc cagcgttgta attatactct tcgatagtga cagtgtctcc acggatatca
    10501 gctacccatg ctacatgacc gtaagcagca tttgactgat aagcgttttt atcaaaccaa
    10561 gcgatagccc ctatgcttgg tgtcttattc acaggataac cctgattttt cgcgatatgt
    10621 ccccacgtgc aggcattacc gtagccttta ggtaactgaa aaccattagc agagcttaaa
    10681 cgaaaagctg caaaagaagt gcattggcgg atatacatgt tccacgaatc gattccattg
    10741 ccttttttcc acttactcgg atagttatcg cctaaaacag ctgcatgaac aagattttcc
    10801 tgttgcgaaa taagtgtaga tggcatagta ggtactagac cattaaaacc taaaaggatt
    10861 actcctgaga ccaaaaaacg atgaaatttt ttcattaatt acctcctgta acttattatt
    10921 cgaaagcaag aaacaaaaaa tgttattttt agatgattat tttgaaaatt ggctttactt
    10981 gatattaaat aactgtttga ttggctaata gagtgttcct tatttcaaga attgtggtct
    11041 actatcacat ttttacaatg tttcaattat tgataactaa tacattatgt aaaaaagcga
    11101 acgtttatga tataatatct aattataata cgaaagaggt ggatgttttg aaattacttg
    11161 ttgttggttc aggtggtcgt gaacatgcga ttgctaagaa gttgttagcg tctaagggtg
    11221 tggatcaggt ttttgtggca cctggtaatg atggtatgac cttggatggt ctggacttgg
    11281 tgaatatagt agtttccgaa cattccaggt tgattgcctt tgctaaggag aatgagattt
    11341 cttgggcctt tattggtcct gatgatgcgc tagcagctgg tatcgttgat gatttcaaca
    11401 gtgctggact cagagctttt ggtccaacaa aggcagcagc ggagctagag tggtcaaaag
    11461 actttgccaa ggaaatcatg gtcaaataca atgtcccaac agcagcctat ggcacatttt
    11521 cagactttga aaaagccaaa gcctacatcg aagagcaggg cgcacctatc gtggtcaagg
    11581 ctgatggctt ggcgctaggt aagggtgtgg tcgtggctga aaccgttgag caggcggtag
    11641 aggcggcgca agagatgctt ctggacaata agtttggcga ttcaggagcg cgtgtggtta
    11701 tcgaggaatt cttggatggc gaggagtttt ccctctttgc ctttgctaat ggcgataagt
    11761 tctacatcat gccgacagct caggatcaca agcgtgcctt tgacggagac aaggggccaa
    11821 acactggtgg tatgggtgcc tatgcgccag ttcctcatct acctcagagc gtggtagaca
    11881 cagcggttga gatgatcgtt aggcctgtcc ttgagggcat ggttgccgaa gggcgtcctt
    11941 atctaggtgt cctctatgtg gggcttatcc tgacagctga tggacctaag gttatcgagt
    12001 tcaactcacg tttcggtgac cctgaaactc agattatcct ccctcgcctg acttctgatt
    12061 tcgctcagaa tattgacgat atcatgatgg gcattgagcc ttacatcact tggcagaagg
    12121 acggtgtgac tttgggtgtt gtcgttgcct cagaaggcta tccattcgat tatgagaaag
    12181 gtgtgccact gcctgaaaag accgacggcg atatcatcac ctactacgca ggagttaagt
    12241 tttcggaaaa tagcgagcta cttctctcaa acggaggacg tgtctatatg ctcgtcacca
    12301 cagaagacag cgtcaaagca gggcaggaca aaatctatac ccaactggcc caacaagaca
    12361 caacaggtct cttctaccga aatgatatcg gaagcaaagc tataagagaa taagactaac
    12421 cattcaaata ttagcgtcag caatcagcga ccgaaggtcg ctccaaaaag aaagaagaaa
    12481 ggaactgaac acgggactaa tttcccagga aaaaaataaa actacctgga cgcaagcgtc
    12541 atcgttagtt ttctgcgtcg taggcgtctg atgctaaagc acctagtcgc cctgacgtgg
    12601 gttcgtcttc gaaatcaaag atttcggact tacctcatat ttttctacgg aaagtttcga
    12661 caagtcgaaa cgcccctttg tatcttaatt atgaaaactc caattatttc tattatcatg
    12721 ggctccaaat ctgactgggc aaccatgcaa aaaacggctg aagttctaga caactttggc
    12781 attgcttacg agaagaaagt cgtctctgcc caccgtacgc cagacctcat gttcaagcat
    12841 gctgaggaag cacgtggtcg tggcatcaaa atcatcatcg caggagcagg tggggcagct
    12901 cacttgcctg gtatggtggc agctaaaaca acgctgcctg ttatcggtgt gcctgtcaaa
    12961 tcacgtgccc tttcaggttt ggatttgcta tattccattg tgcagatgcc tggcggtgtg
    13021 cctgtggcaa ccatggctat cggagaagcg ggagcgacta acgctgccct gacagccctc
    13081 cgtatcctct ctatcgagga ccaaaatctg gctgatgcgc tagctcattt ccatgaggaa
    13141 caaggaaaaa tcgcagagga gtcaagtggt gaactcattt aagaccattg ggattatcgg
    13201 tggtggtcag ctggggcaga tgatggccat tgcggctatc tatatgggtc acaaggtcat
    13261 cacgctggat cctgctagcg acagccctgc ctcccgcgtt agcgaggtaa ttgtggcgcc
    13321 ttacgatgat gttgaggctt tgggacaatt ggctgcgcgt tgcgatgtgt tgacttatga
    13381 gtttgagaat gttgatgcgg acggtttgga tgccgttgtg tcagcttgtc agctaccgca
    13441 ggggaccgat ctgctccgca tttcccaaaa ccgtatcgtt gaaaaagact ttctggcaaa
    13501 taaggctggt gtgacagtcg ctccctataa ggtggtgacg tctagccttg acctaggggg
    13561 gcttgatttg accaagacct atgtcctcaa gacagagaca ggtggttatg acggtcatgg
    13621 gcaaaagatt atccgctcag cagaagattt gccagaggcg cagcaattag ctaactcagc
    13681 tcagtgtgtc ttggaagagt ttgtcaactt tgaccttgaa atctcagtca tcgtgtctgg
    13741 aaatggcaag gatgtgacgg tctttcccgt tcaggaaaat atccaccgca acaatatcct
    13801 gtcaaaaacc atcgtaccag ctcgcatctc agatcaactg gctgataagg ctaagaaaac
    13861 ggcggtgcag attgccaaga aactccagct gtcaggaact ctctgtgtgg aaatgtttac
    13921 gaccgcagat gatatcattg tcaatgaaat tgccccacgc ccccacaact cagggcgcta
    13981 ttctatcgaa gcctgcgact tttcacagtt tgacacccac atcttgggtg tgttgggcgc
    14041 accacttcct cagattcagc tccacgcccc agccgtcatg ctcaatgtcc taggacaaca
    14101 tgtccagcag gcaactgact atgttgccaa aaaccctagc gcccacctcc acatgtatgg
    14161 taaactagaa gcgaaacata accgcaaaat gggacatgtg acggtgtttg caaaagatgc
    14221 ggatgaggtg aaggagtttt aaagagttaa ttaggagatg tttattttat ggcaaatatt
    14281 caaataaata gaataaaaag taaattgaca gaactgttta gtagtattat ctatatgggt
    14341 aatatcaaag ttgatgagga ctctgaagag tataaaaaaa tgtggtatag tagggcttac
    14401 tcagcttatt caacttttct acttggagca gaaaatgtag atgaagcaac taagtcagtt
    14461 acggatggat ttgctgataa tggcatagat gccatctata acgataaaaa taaaaaaatt
    14521 ttatatttta ttcaaactaa atttagcaat gaagca
//
LOCUS       DAUGQX010000044        13648 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUGQX010000044 DAUGQX010000000
VERSION     DAUGQX010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13648
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.044"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(425..1870)
                     /locus_tag="VIA51_001424"
     CDS             complement(425..1870)
                     /locus_tag="VIA51_001424"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEQ8683362.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            complement(2052..2762)
                     /locus_tag="VIA51_001425"
     CDS             complement(2052..2762)
                     /locus_tag="VIA51_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEQ8683363.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            complement(2893..3390)
                     /locus_tag="VIA51_001426"
     CDS             complement(2893..3390)
                     /locus_tag="VIA51_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEQ8683364.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVREDMAKIRASSLISDDVVINGAVYDVDTGKM
                     TQVME"
     gene            complement(3579..4940)
                     /gene="radA"
                     /locus_tag="VIA51_001427"
     CDS             complement(3579..4940)
                     /gene="radA"
                     /locus_tag="VIA51_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEQ8683365.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNA
                     VFS"
     gene            complement(5021..5467)
                     /locus_tag="VIA51_001428"
     CDS             complement(5021..5467)
                     /locus_tag="VIA51_001428"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEQ8683366.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            complement(5577..6344)
                     /locus_tag="VIA51_001429"
     CDS             complement(5577..6344)
                     /locus_tag="VIA51_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEQ8683367.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            complement(6462..8246)
                     /locus_tag="VIA51_001430"
     CDS             complement(6462..8246)
                     /locus_tag="VIA51_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683368.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLIQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTMTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            complement(8249..9955)
                     /locus_tag="VIA51_001431"
     CDS             complement(8249..9955)
                     /locus_tag="VIA51_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683369.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            complement(9948..10397)
                     /locus_tag="VIA51_001432"
     CDS             complement(9948..10397)
                     /locus_tag="VIA51_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8683370.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            10695..11711
                     /locus_tag="VIA51_001433"
     CDS             10695..11711
                     /locus_tag="VIA51_001433"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8683371.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            11744..12643
                     /gene="galU"
                     /locus_tag="VIA51_001434"
     CDS             11744..12643
                     /gene="galU"
                     /locus_tag="VIA51_001434"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEQ8683372.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(12742..13413)
                     /locus_tag="VIA51_001435"
     CDS             complement(12742..13413)
                     /locus_tag="VIA51_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEQ8683373.1"
                     /translation="MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
BASE COUNT         4168 a         2967 c         2459 g         4054 t
ORIGIN      
        1 taataaaaac atatattcgc tattagccat ttttttctcc tttccaactt tattatttta
       61 gcatatttta tgacaatgat tacaatatta tttgattaca attgattagc taagtgagta
      121 ctaaactagt ctctttcagt atataccaaa aaaatattgt acactaattg attcataaaa
      181 accatttctt taaatcacac taatcaaaac ctcaccgttt gctgtcatta tcacgtaagc
      241 atctcaccac ctctctttca aatccaatct ccaaaataga aataaactat actatttttt
      301 actttaccaa ggtagcaagc tcagataacg ataaaaaaga ctgaagaact taatcttcaa
      361 tctttcgttg tcgtgacttt ttaactcctt aaagcgttta aaaataaagg tgaacgatac
      421 agccttatag catgtttttg atgtgctcaa tggatttatc acgtcccaat aaataaatcg
      481 tatttggtaa ttctgggcca tgcatttcac cagatactgc aatacgaata ggcataaaga
      541 ggtttttccc tttgattcct gtttcttttt gaacagcctt aatttgtggg aaaatatttt
      601 ctggtttgaa gtcttcatct gacatagctt ccaacttagc cttgaaagct tgcaagactg
      661 tcgaaactgt ttcacctgcc atcacttctt tttcggcttc tgttaattca gggaaatcag
      721 aaaagaaaag gtcagtcaat ggaataatct catctgcaga ttttaattga ggtttgtata
      781 attctactag cttctcagct ttttctgtca aacggcctgc ctcttcaagg aatggtttgc
      841 agagggcata aactgtttca aaatccgcat gtttaagata ctcattgctc atccaatcca
      901 ttttcttctg gtcaaaggca gctggcgact tgctaaggcg attttcatca aaaagggcaa
      961 tcagttgctc acgagagaag atttcctctt ctccgccagg attccagcca agaagggcga
     1021 tgaagttaaa gacagcttca ggcatataac cttttttgcg gtaatcttca atgaattgga
     1081 gggtattggt gtcgcgtttt gataattttt tacccgtttc agaattgatg ataagagtca
     1141 tatgaccaaa ctctggcgct tcccagccaa gagcttcata gaccatcaat tgttttggcg
     1201 tattggcaat atggtcatcg ccacggataa cgtgagaaat ttgcatatca tgatcatcaa
     1261 caacaacggc aaagttataa gttggatagc catctttctt ttgaataacc cagtcaccac
     1321 cgatgttacc accttcaaac tcgatatcgc ctttaaccat gtcagtccat ttgtaaatac
     1381 cggactcatt aacagcaaga cggactgttg gaacgatacc tgctgcttca cgctcagcaa
     1441 tgtacttagc tttttcgtca gctgacatac caataaattc attgatatag cgaggcgttt
     1501 cgccagctgc ttcttggcgt tcacgctctg ctgccaattc ttcctcagtc acgtaagact
     1561 tgtaggcttt tccttcagct aacaattgat caatatattg ttgataaagt gctagacgtt
     1621 cagactggcg gtaattttca tgcgtttctg ggctttcatc ccaatccatt cctaaccatt
     1681 ttaggttttc aagttgagaa cgttcaccat cttcaacatg acgtttacgg tcagtatctt
     1741 caatacgaat gataaaagta cctccgtgac gacgggcata aaggtaatta aatagggctg
     1801 tgcgggcatt cccgatatgt aaaagccctg ttggacttgg tgcataacgc acacgaattg
     1861 gtttagacat gcttcttctc ctgttacata tatcactcag aaacctgtgg cacgaaaaac
     1921 aagcaacaaa tgatgatttg agcttgccaa gaccttttca gacttcttct aaaatctttc
     1981 ttattatagc atattttact tgcttaggcg aaaaaaatca gccctaaaaa gctgatttta
     2041 tgttattttg actaatttga actagttggt agataacgtt taagagtccc agcaaattgc
     2101 tcaaggttaa gactttggat ataaatctca ccatgacctc taaaggtatt aacaactcct
     2161 tcacctgtac caattgactg cataaagcca ttttctaaat gaatatcata atcaagttct
     2221 ctgctccatg ctacaacatg ggcattatca atagtcattg tgccaccatc aagtgtgatt
     2281 ttcttgatag atccaaacga gttagcaagt aaggtaccaa ggccttcagt tgtcatgaca
     2341 aaaagtccgc cttgaccacc aaaaagtgct tttccaatat tttgacgttc cattttgtac
     2401 tgtgctgaac catctagggc tagaaaggca ccatcattta gacgatattg tttttcacct
     2461 agttctaaag caacaatctg tcctggtgta ttgggtgcta atgctaattt accatctcca
     2521 tttgacatag cttgtgtaat gaacattgat tcaccagaaa ccatggaacg gccgatggct
     2581 ccaactaatt ttcctaaacc agatccctta ccattcaatt tggtattcaa ggttacattc
     2641 tcagtatgat aaaccatact tccttgttgt aagtaaactg atcccccatg ttccagatca
     2701 atctcaacta gtggaaattg catgttttga tcaatcgtaa atctcattct attgtcgacc
     2761 atcttactct ccttgtttgt atgaataact tgatacaatt attataacgc ttccctattt
     2821 ctttgtctaa tattttcaat aatttttaaa aataaaaaag agctgaattc agctctacaa
     2881 cttggctact aactattcca ttacttgtgt catctttcca gtatccacat cgtagacggc
     2941 accgttaata acgacatcat cagagataag agaggaggct cttatcttag ccatatcctc
     3001 gcggacactg tcttccacat cttggaaggg aaggaaatct tgccctgaaa catccacacc
     3061 taagtgctca tgaatatgct tggcaaagcc ttcattagta aaagtctgcg cgccacaatc
     3121 tgtatggtgg agaaccacaa tctctctcgt tcccatttgc tgctgagaaa taaccagcga
     3181 ccgaatcatg tcttcggtga cacgtccgcc agcattcctt aaaatatgag catctcctag
     3241 agccagcccc agagcttggg ccacatgtag ccgtgaatcc atacaagtca caatcgctac
     3301 tttagtcttg ggttttaagg gcaaatgagc tgtcccatgc aaggccacat aagcctgatt
     3361 ggcagccata aaatgttcaa aataagacat caataaactc cttttgagaa acagcagagc
     3421 tatttttgct gttagtttgt cttatcttaa catcttttat ggaaaatagc tggattaacc
     3481 tcttagacgg tcggtatcgt tcgaaaagtt aaaaaaacaa atgattggga tactttcttg
     3541 acaaatttcc tcctcatttg ctcttagttt ctgatcctct agctaaaaac tgcatttaaa
     3601 acctgaccaa ccgtagtcac tccgacaacc tcaatacctt gagggatatc aatgccttgc
     3661 aaggcatttt taggagcata gaccttggta aagccaagct ttgctgcttc attaatccgt
     3721 tgctcaatac gggtcactcg ccgaatctca cctgttaacc cgatctcgcc taagaaagct
     3781 tcttgagggc tggttggttt ttccttataa ctggatgcga tagccacagc gactgccaaa
     3841 tcaatggcag gttcgtctag tttgacacca ccagccgact tgaggtaggc atcttgattt
     3901 tgtaagagta aaccacagcg cttttctaaa actgccatta ttaggcttac gcgattgaaa
     3961 tcaagtcccg tagtggttcg tctggcattg ccaaaaacgg ttggtgtcac taaagattgc
     4021 acctctgcta agataggacg acttccttcc atcgttacaa cgacagccga tcctgttgcc
     4081 ccatctaagc gttcctctaa aaagacttga ctaggattta agacctctac caagccgcca
     4141 gactgcattt caaaaatgcc aatctcgtta gtggagccaa agcggttttt cacagcccgc
     4201 agaatgcgaa aggtgtgatg cctttcccct tcaaagtaga gaacggtatc caccatatgt
     4261 tctaacatac gaggcccagc caaggttcct tccttggtga catgacccac aataaaggtt
     4321 gcaatgttgt tcgtctttgc aagctgcatc aattctgcag tgacttctct cacctgactg
     4381 actgatcctt gaacacctgt aatatcaggg ctcatgatgg tctgaatgga gtcaataatt
     4441 aaaaaatctg gtttaatatt ttcaatttct gtgcgaatag cttgcatatt ggtttcggca
     4501 tagaggtaaa attcattgtc aatatcaccc agacgctcac tccgcagttt aatctgctct
     4561 gctgattctt ccccagacac atagagaacc gttcccttat tagcgagctg cgtggatacc
     4621 tgcaagagta aggtggattt tccaatacct ggatcaccac caattaaaat caagcttcca
     4681 ggaaccacac cccctccaag aactctatta aattcagaca tgtcagtctg tgttctgtga
     4741 taactaatat tatccacatc ttttagttta accggtctgg acttttctcc agctagacta
     4801 acacgggcat ttttgacttc tttgacctct acttcttcca caaaagaaga ccaggccgag
     4861 caatttggac agcgccctaa atactttggc gactggtagc cacactcctg acagataaag
     4921 gttgcttttt tctttgccat agtaatctcc ctcccctata caagacaaac ccactcttaa
     4981 agaataggtc tgctgtcata agcatttttg ttaaatcgct ttactgccct gtcgaaccaa
     5041 aaccacctgt tcgttcacct ctggcttggt caccatcagc aattaaaaaa ggcataaaaa
     5101 caccctgaac gatcctctca cccacagcta atgtcacagg gtgatctgta atgttttgca
     5161 tttgtgcaaa aatatgtcct tcattagcct cattaccata ataatctgca tcaatcacac
     5221 ctactgaatt aatcaggata atcccttttt ttcgtggatt tgacgaacga tcatagaggt
     5281 aaagcacctc gccatcttgc atataggcct taacccctgt tggtaccaac ttaatctccc
     5341 ctggggcaat ggttacagcc tcagcaacag acaggtcata accagctgca tgagtcgtct
     5401 cacgttttgg tagtaaatca ggattagtaa agcttgaaac aagctcgaaa ccacgaattt
     5461 ttgtcattat gataggtata tcctttcaag tcaatcatat cctcttatta tagactattc
     5521 gtaaaagaat agcaaaaaag cggtcaactt taaacggacc acttttaatc atgccatcac
     5581 atctcatccc cacgataact aaagcggatg tgggtgaaat cattatccaa atccttgtct
     5641 gccataaaag ctttggcatc ttttttcact tgaaccaagt caataccttg cattttggca
     5701 gcatagacac agccacaata gcattggcgg taaatatcat actcctcaca catttcaacg
     5761 gatctgcgat aaccgttgtt tttcttgaaa tcacttggca ggtatttggt ggtgtaaacc
     5821 ttttgcacat cgatgcccac atcattaatg gtttgcgaat ttttatgagg actgatggtt
     5881 agggcactgg caaagtagtc aaaaccaagt tccactgctt tttgagcggt cttgtctagt
     5941 cggtaatcaa aacagacacg gcaacggtcc ccaccttctg gttcctcttc taagcctcgc
     6001 acttgtcgaa cgtactcatt ggggacatag tccgcttcga gaaactgaac agtattgcct
     6061 gttttagcgt tgaactcgga gacaaactgt tgtgtcacat aagctctgcg atggtattcg
     6121 tccttagggt gaatattaga attggcaaag taaaccgtaa tgtcagcaaa ctgcgtcagg
     6181 tattctaggg tgtaagtgga gcatggggcg cagcagacat gcattaaaat actggggcgc
     6241 acggattcct tctcccaaac cttggccatc tgttgcatga ccctgtcata atttatcttt
     6301 tgattgggat tcatgttagc gagaatctct tgtaaatcaa tcattgtggc tactttctaa
     6361 ttgttttttc tcttgcttgc tattatacca tatcagaaaa gaaagcttga ctgctttatt
     6421 gttcaccaaa aaactccgct aagacgcgga gctgatgcca tctattcaaa gacaaattga
     6481 ttgtgataca attcggcata aaagcctttt tgatgcaata gctcatgatg atttccttgc
     6541 tcaatgacct tgccatcttt caacacaata atgtgatcgg catttaaaat ggttttgagg
     6601 cggtgagcaa tgacaaagct agttcgacct gccacgatag cttccatggc ccgttgaatt
     6661 ttactttcgg taaccgtatc aacatttgaa gtggcctcat ccaaaatcaa cacttcaggg
     6721 tcagtcagta gcgtcctagc aatagaaatc aactgctttt gacctgttga aaagacattg
     6781 tcatcatctg agacataggt attgtaccct tttggtaagg acatgataaa gtcatgaata
     6841 tgggtcgcac gcgcagcagt ttcaaccatg tcttgactaa tggtctgatc accaaaacga
     6901 atattatccg taatggttcc tgaaaaaaga actgactctt gcaacacaat ccctaccttt
     6961 tgacgaagac tatccaaatc gtagtcacga atatcacggc catcaaaggt aatcgaacct
     7021 gcatccacat cgtagaaacg gttaatcaag ttcataatag tggtctttcc agaacctgtc
     7081 ggtccaacca cggcaatcat tttgcccttg ggtgcaacga ttgacacatc tgataaaact
     7141 ttttgcccag gaagataccc aaaatcgacg tggttaatcg ccactgcttc ttttaagctg
     7201 gtgaacgctg gtgcattttg tggacgaact tcttcggttt catcaaacat ttcttgaata
     7261 cggtgagcac cggtaaaggc cagctgcaat tctccccaac tagacgcgat ttgcatcatg
     7321 ggttggtaat attgctggga atattgtaca aaagtaacca ctaaaccaag cgctgccgct
     7381 gctggcatag atttgtcact gaggacaatt gttgaaccga caaaaatcac gatagccgtg
     7441 ttaataaggc tcattccatt catgactgga aataattgtc ctgagaacag acggcgtttg
     7501 aaggtggctt gtcgaaccct ttcattatgc tttaaaaagg ctgtcatcgt atcttcttgg
     7561 acaccttgta caataatagc cttttgtcct gaaatggttt catccataaa agcatttaaa
     7621 gcactgactt cttgctgttg gatattggtg tattttcttg ccaaacggat gttaatcact
     7681 aaaaaaatga gagcaactgg ggttgatgcg atggttaaca aagctaaacg gctatcttgc
     7741 ctaaacatca tccagaccag gccgatgtaa agggcaatat tagtcaccac ttgaatcaag
     7801 gattggttca gcgagttttg aatattatcc aaatcactcg tgaaacgaga aagaatctcc
     7861 ccatctttat ggcggtcaaa aaaggcgacg gttaaacgtt ctaatttacc aaataagccc
     7921 ttgcgcatgc ggttagtcga atgtgagaca acacgtgtaa gtaagaaact atatattaga
     7981 ttagctaaaa cagtaaagaa ataagtcatc aaaagcttaa acatcacggc attaaaagct
     8041 gataaatcag ggctaaaatg tgtctggcca ctcatcttag caacgtaata agcctgaccg
     8101 atttttccca actcagtcaa ggactctcct aagaagacag gagcttttac ttgtaaataa
     8161 gttgctaaga taacggcaac agcaatgaca gtaaatgaga aacgatagcg tttaaaataa
     8221 aaccagaaaa aacgtgctgt tttcatcact actcctccct tcctttttgt gtctcataaa
     8281 tttcacgata aatcgcatta ttagccacca actctgcgtg tgttccttct ccaattaact
     8341 gtccttggtc aaggactaag atcttatctg ccttaactac cgatgaaatt ttttgagcaa
     8401 caataactgt agttgtacct tctaatttat gacttaaggc ttcttgaacg cgtttttcag
     8461 attttgcatc aagagctgaa gtggaatcgt ctaatataag aattttggga tgattaatga
     8521 caccacgtgc aatagacaga cgttgctttt gtccgccaga caagttacta cctcgctctt
     8581 caacttggct ctcataacgg ctatccatac gatcaataaa ttcttttgct tgcgcgattt
     8641 gagcggcttt ttgcatagca tcaatatcag cttttgctga gccttggcga aggttatcag
     8701 ctatcgttcc tgaaaagaga atagcctttt gcaacacgat ggaaaccgat tggcgcaggg
     8761 ttgtttgact tagggtttta atcggctttc ctcctaacaa aatttggcca tcttgaggat
     8821 caaataagcg agggatgagc tgtgcaagcg ttgatttccc agatcctgtt gcaccaacga
     8881 tgccgaccat ttgcccaggt tcaatagcaa aagaaatgtg cttcaaggtt ggctcatcat
     8941 cattaggata tgtaaaacta acatcgtcaa atacaatgct tcctgagatg gtttcttcct
     9001 tttcattttc aaatgtcatg gcaggttctg tagacaatat ttgcctaatt ctagccatag
     9061 aaacaaaagc acgactaact tgcatcccca tggaaccaac cacaataatt gaaaacataa
     9121 tttgcatcat ataagtcatg aaagaggcaa tattcccaat cactgttgga tctgtttcga
     9181 ccatggtcga aacaacattt atagaaacat aaactgccaa ataagacacc aacattaaag
     9241 ccggctgcat tagtgaaaaa ccataaccaa tagataaatt taacgccaaa agatcattgg
     9301 acgtttcttt aaatttagtg tattgttgtt gttcttgtac aaatgattta accacgcgaa
     9361 cgccacggag attttcctta gcgatgcgat taatcttatc cattaaccgt tgaaatttac
     9421 caaaacgagg acccatttga cgcatcacca aacccatgat gagggcaatt aagataacca
     9481 ttacaacaat gacccaccat aattgaggga atgtctgaac tgccataata aacgcgccaa
     9541 taaaaaggat cggcaaacga aagagaattt gaaacatcat catgactaaa ctttggattt
     9601 gattgatatc attagttagc ctaaccacaa gattaccagc attaaaagct tcaatattgg
     9661 catatgaaaa gtcttggatt tttcgaaagg tcttctccct catatcagca gatacacctt
     9721 gagctatttt agcagctaaa accgtattaa tcgctccaga cattaaccct aaaagggcaa
     9781 taataagtaa tggtttccca acctcataaa ttttctcttg attattttga ataacagcgc
     9841 ttagcacaga tttaagataa tgtggttgca agagactact tgcaacaacc ccaataacca
     9901 taaaaaatga gcctaaagca taccatttat aacgtaagat tgcgtcttta agcatcgttg
     9961 tctcctttat aagttagcat attttgcttg agctgttcaa ttactttttt cgctgtcagc
    10021 aactcttctt ttgtaatttc ttttaaaaaa tagtgctcga tatccttacg acactcccgc
    10081 aacaaaggca atttatctct accaacctgc gctaacacta cttgcttata acgcttatcc
    10141 acttgggaag gcatcacatt gataaaccca tttttgacca tacgtttcac taaatgacta
    10201 gcaactgact ttgagatacg aagttgtttt tcaatatctt tgacaaatat ttcttgattt
    10261 tggtgtttag ctaaaaaaac aagaacataa ccttgaggac ctgctagatg ctctacatca
    10321 tatttttttg caatctcatc actaatttgt tcgatttgat gtatcaattc acgtaaatca
    10381 cctatcactt gtgacatctc ttccctcctt attttcttta atagtttcta tgataagtat
    10441 tttagttctc tagataacta ttgtcaatta aaatatcttt atttttaaaa ataagtttcc
    10501 gaacttaaat aactaaaaag aacagggcaa agccatgaca acagctcacc tgatgaagct
    10561 tattaaacaa cattattaat atagctagct ctcttgggaa cgccttatta gccaagacca
    10621 tatacctttt ctaatagagc taatcaaggt gttatgttat aatagagtga ctagctcttg
    10681 aaggagaatt tagaatgaca aaacaaaaag tagctatttt aggacctggt tcttggggaa
    10741 ctgccctttc tcaggttctt aatgacaatg gccatgacgt ccgtttatgg ggaaatattc
    10801 ctgatcaaat tgaagagata aataccaagc ataccaatag acactacttc aaagacattg
    10861 tgttagacaa aaacattacg gcaactcttg atttaggtca agccctatca gatgttgatg
    10921 cggtgctttt tgttgtgcca actaaagtaa cacgattagt tgctagacaa gttgccgcca
    10981 ttttagatca taaagtagtg gtcatgcatg cctcaaaagg tctagaacca gagacccacg
    11041 aacgtttatc aactatccta gaagaagaaa ttccagctca ttttcgtagt gaagtggtcg
    11101 ttgtatcagg tcctagtcat gctgaagaaa ctatcgttcg cgatattact ctcatcacgg
    11161 cagcctcaaa agatattgaa gctgcaaagt atgttcagtc cctctttagt aaccactact
    11221 tccgacttta taccaatacc gacgtcatcg gagttgaaac agctggtgcc ctcaaaaaca
    11281 ttattgctgt tggagcagga gctctccatg gacttgggta tggagataat gccaaagcag
    11341 cggtaattac tcgtgggtta gctgaaatca cccgtctagg cgtcaagctt ggtgctgacc
    11401 cgttaaccta cagtgggtta tctggtgttg gtgatctaat tgtaacaggt acttctgtcc
    11461 attcacgtaa ctggcgggct ggagctgccc ttggacgtgg tgaaaaatta gaagatattg
    11521 aacgcaacat gggtatggtt atcgaaggta tcgcaacaac taaggtagcc tatgaaattg
    11581 cccaagacct cggagtttac atgccaatta caacagctat ttataagtcc atctacgagg
    11641 gcgctgatat caaagaaagc atcctcggca tgatgtcaaa tgaatttcgt tctgaaaatg
    11701 aatggcatta agccatgcgt cactaaaata agaggaggtg ctgatgacca aagtcagaaa
    11761 agctattatt cccgcagcag gtttaggcac acgtttttta cctgcaacca aggcccttgc
    11821 caaggagatg ctacctattg ttgataaacc aactattcaa tttatcgttg aagaagctct
    11881 aaaatcaggt atcgaagaaa ttcttatcgt tactggaaaa tccaaacgct ccatagaaga
    11941 tcattttgat tctaattttg aattagaata taatttacag gctaaaggaa aaatcgaact
    12001 tctaaagtta gtagacgaga ccacttctat taatcttcac tttattcgac agagtcatcc
    12061 aagaggatta ggagacgcag ttcttcaagc aaagaccttt gttggcaatg aaccttttgt
    12121 tgtcatgcta ggtgatgatc tgatggatat tacaaatcca aatgtaaaac cattaaccaa
    12181 acaattgatc gatgactatg aagaaactca tgctgcaact attgccgtca tgagggttcc
    12241 tcacgaggat gtctctaact acggtatcat tgctcctcaa gcaaaagcag taaaaggact
    12301 ctatagtgtg gatacttttg ttgaaaaacc acaacctcaa gatgcaccta gtgatttggc
    12361 aattattgga cgttacttgc tcacaccaga aatttttagt attttagaaa aacaagaacc
    12421 tggtgcaggc aatgaagttc aactgactga tgctattgat accctcaata agacacagcg
    12481 tgtctttgct cgtgagttta aagggaaacg ctatgatgtt ggcgataaat ttgggtttat
    12541 gaaaacttct ttggattatg ccctgaaaca ccctcaagtc aaagatgact tgaaagccta
    12601 catcatccaa ctgggcaaag cactagagaa gacaaaacca taaaaataag gagggaaaat
    12661 ccctccttat ttttatggtt tttaagtcat ttcatcctac tagccatctg agaagtaaca
    12721 gtgctaacca ctcacttatt tttataaaaa cccaagcact aacacaccaa ccaaaataat
    12781 accatagctc actaaagcca acattcgctt ggttttcttc actgttatca ctctcatctt
    12841 agttggaaaa actatactca gtaacgcacc acccacgaca ccgccaatat ggcctgccat
    12901 actcacgttt ggcataaaaa gattcatcag taaattgact acaattaacg tctggtatga
    12961 cttgcccaaa tctttcaacg cttggttctt acccaaaaaa ctcaatacta caatagcagc
    13021 aaaaagtcca aataacgacg tcgatgctcc tgcagctact gtttcaggag tcaaccaaaa
    13081 agtaaaggca ttgcccataa cacctgataa aacataaagt aataaaaaac ggcgtgagcc
    13141 ccagaggtct tcgacgattt gaccaacaaa atatagtgtt aatccattga caaaaaaatg
    13201 accaaagccg atatgaataa atatcggagt caccaatcgc cacaactggt ctggcattgc
    13261 ttttactagt aatccaaaca tacctccaac ttgataaata gcttgagcac cagttgctaa
    13321 atgtccatat accacttgca ttgctataaa aattaagcct gttaacccta aaaggaaaat
    13381 agtaatagga tatcgtttta ataactgtgt catctaagat aaacctccta aacagcaata
    13441 tcataaatcg tttgatttgg caatcgtatt ggcccgctga taagcttgat tgctaacaac
    13501 atccactaat aaagcttgat cattttgacg ttttaagtct acatccatag ttcgtaaaga
    13561 ctagaagagt tctttgagaa tctctttttt catcatcttc ttatcatacc ataaattagg
    13621 aaaaaggttc aaggctgaca agaaacta
//
LOCUS       DAUGQX010000045        13494 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUGQX010000045 DAUGQX010000000
VERSION     DAUGQX010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13494
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.045"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..763)
                     /locus_tag="VIA51_001436"
     CDS             complement(<1..763)
                     /locus_tag="VIA51_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683374.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGWEGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFII"
     gene            complement(773..1471)
                     /locus_tag="VIA51_001437"
     CDS             complement(773..1471)
                     /locus_tag="VIA51_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683375.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(1471..1842)
                     /locus_tag="VIA51_001438"
     CDS             complement(1471..1842)
                     /locus_tag="VIA51_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8683376.1"
                     /translation="MSWKFEEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            2027..5137
                     /locus_tag="VIA51_001439"
     CDS             2027..5137
                     /locus_tag="VIA51_001439"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEQ8683377.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEIEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYFCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDALTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDITAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSVTEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            5217..6230
                     /gene="pfkA"
                     /locus_tag="VIA51_001440"
     CDS             5217..6230
                     /gene="pfkA"
                     /locus_tag="VIA51_001440"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEQ8683378.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKDGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            6293..7795
                     /gene="pyk"
                     /locus_tag="VIA51_001441"
     CDS             6293..7795
                     /gene="pyk"
                     /locus_tag="VIA51_001441"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8683379.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            8013..8570
                     /gene="lepB"
                     /locus_tag="VIA51_001442"
     CDS             8013..8570
                     /gene="lepB"
                     /locus_tag="VIA51_001442"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8683380.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            8746..10560
                     /gene="glmS"
                     /locus_tag="VIA51_001443"
     CDS             8746..10560
                     /gene="glmS"
                     /locus_tag="VIA51_001443"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEQ8683381.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKSLSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LAAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            10756..11091
                     /locus_tag="VIA51_001444"
     CDS             10756..11091
                     /locus_tag="VIA51_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEQ8683382.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            11197..11838
                     /locus_tag="VIA51_001445"
     CDS             11197..11838
                     /locus_tag="VIA51_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8683383.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            11848..12477
                     /locus_tag="VIA51_001446"
     CDS             11848..12477
                     /locus_tag="VIA51_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683384.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            12493..13329
                     /locus_tag="VIA51_001447"
     CDS             12493..13329
                     /locus_tag="VIA51_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8683385.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGRCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         4256 a         2225 c         2801 g         4212 t
ORIGIN      
        1 tgataataaa attagtggcg aggtaaaaca ttatcatttc aataaattgt tccaaaataa
       61 gaagataaat tgttttttgc tcagtaaatg ggaaactatc ggcacttgta ttaatattaa
      121 agatgtgact gtgaacatat gttgcagcaa cgctaatcag aataactaat ataaaatatg
      181 caataaaggc catcaagcct cgccgattgg aaaaaagttg acctatagaa atggaaagat
      241 aaattaataa gatactcgta aatgttgata ataggacata ggctagtaca gttagcatat
      301 tgatgaaata atccatctta aaactattaa agaatccttc taatagttcg ttgatgttaa
      361 acattggtac aattacaata gcgatagcaa atgcaaggat gatagtattg aaaacactgc
      421 aaataaaaga agctagtagt tttgataaaa taatttgatg cgaattgacg ggtaaagtca
      481 acgttaagta tccttcccat ccaaaaacac ttttgctgaa acgtttgata atgataagta
      541 atgttgataa gagggaacca gcgatcaggg agccaaaagt taaacctaat gtcagaggca
      601 acatcttatt ggttagtact ccaaatagtc catcactatt gctttgagca aacagtttta
      661 tcgtaaatga caaaatggca gcgatggcaa taacgaaagc attaagcgca aagtaccatt
      721 ttccaataga tctaaattcg tattttaata attttccaaa catgatatcc tcctaaacct
      781 tataagtttc cctaaagagg gaatcaatgg attgctggta ttcttgtctt agatcatcag
      841 cattgccaga taagaaaagt cttccttgtt tcaagaaaat gacttcgtca aggataggtt
      901 caatgtccga aatcaagtgg gttgagataa taacagaagc attttcacaa taactattaa
      961 tgatggtttt taggatgtag tctcttgcgg cagggtcaac tccaccaata ggttcatcaa
     1021 gtacatagag tctggcttta cgactcatca caagaattaa ttgtactttt tctttgtttc
     1081 ctttggatag agttttgaag cggtcttcag ggtctagttc taaatctctt agaaggcttg
     1141 ttgctttgga tttgtcaaag tcgctgtaaa aatcactaaa gaactccaac atgtccttaa
     1201 ttctcatatt ttcattaaga taagtagtat ctggtaaata agaaataatt ttttttgtct
     1261 caacacaggg acggtagcca tcaatgacaa tttctccttt atttggttgt aaaaggccat
     1321 taatgagttt aattaaagtt gttttaccac ttccatttgg acctaataat ccgataattt
     1381 taccgttcgg gatagtaatg gttaagtcat caatagcttt tttttcacgg taagattttg
     1441 aaacatgatg tagttgcaat aggtgtgcca ttattgtgaa tcctccttta aaaagctcgt
     1501 caaaacaggg ataatctcag tgtgactaaa tcccattttt gtcatattgg tgataaatga
     1561 ttctaattca ctaattgcta actctcgtct tttacgagca attaattttt gatcgtcagt
     1621 tacaaaacgg ccagcagtac gttgcgaata aaccattcct tcccgttcaa gttctgtaaa
     1681 cgctcgttgc atggtgttag gattaacacc tgcgatttct gcatattcac gaacagttgg
     1741 aagttgatca ccactcttga tttcttggct aataatttgc atcatgacat gttgtgctat
     1801 ctgcgcataa ataggagatt tttcctcaaa tttccaagac atgtggtctc ctttctgagt
     1861 aatatagata tttgtactaa ttaaatggta cagaaaaaaa aagggaatgt caagttttat
     1921 gccatttttc actctttgag aagtagacgt agattagaga gaaaattgaa gcaagaaaac
     1981 ctttttcata gtataatagg gaacaagata accaaaggag gaacttatgt ttgctcaact
     2041 tgatactaaa actgtatact catttatgga tagtttaatt gacttaaatc attattttga
     2101 acgagcaaag caatttggtt accacaccat aggaatcatg gataaggata atctttatgg
     2161 tgcttaccat tttattaaag gttgtcaaaa aaatggactg cagccagttt taggtttgga
     2221 aatagagatt ctctatcaag agcggcaggt gctccttaac ttaatcgccc agaatacaca
     2281 aggctatcat cagcttttaa aaatttccac ggcaaaaatg tctggcaagc ttcatatgga
     2341 ttacttctgc caacatttgg aagggatagc ggttattatt cctagtaagg gttggagcga
     2401 tacattagtg gtcccttttg actactatat cggtgttgat cagtatactg atttatctca
     2461 tatggattct aagaggcagc ttatacccct aaggacagtt cgttattttg cgcaagatga
     2521 tatggaaacc ctgcacatgt tgcatgccat tcgagataac ctcagtctgg cagagacccc
     2581 tgtggtagaa agtgatcaag agttagcaga ttgtcaacaa ctaaccgcct tctatcaaac
     2641 acactgccct caagctctac agaatttaga agacttagtg tcaggaatct attatgattt
     2701 cgatacaaat ttaaaattgc ctcattttaa tagagataag tctgccaagc aagaattgca
     2761 agacttgact gaggctggtt tgaaggaaaa aggattgtgg aaagagcctt atcaatcgcg
     2821 cttactacat gaattggtca ttatttctga catgggcttt gatgattatt ttttgattgt
     2881 gtgggattta cttcgctttg gacgcagtaa aggctattat atgggaatgg gacgtggctc
     2941 ggcggcaggt agtctagtgg cttatgctct gaacattaca gggattgatc cagttcaaca
     3001 tgatttgcta tttgagcgct ttttaaacaa agaacgttat agcatgcctg atattgatat
     3061 cgatcttcca gatatttacc gttcagaatt tctacggtat gtccgaaatc gttatggtag
     3121 cgaccattcg gcgcaaattg tgaccttttc aacctttggc cctaaacagg ctattcgtga
     3181 tgttttcaaa cggttcgggg ttccagaata cgaactgact aatctcacta aaaaaattgg
     3241 ttttaaagat agcttggcta ctgtctatga aaagtcaatc tcttttaggc aggttattaa
     3301 tagtagaact gaatttcaaa aggcttttgc cattgccaag cgtatcgaag gaaatccaag
     3361 acaaacgtcc attcacgcag ctggtattgt gatgagtgat gatgccttga ccaatcatat
     3421 tcctctaaaa tcgggcgatg acatgatgat cacccagtat gatgctcatg cggtcgaagc
     3481 taatggcctg ttaaaaatgg attttttggg gttaagaaat ttgacctttg ttcaaaaaat
     3541 gcaagagaag gttgctaaag actacgggtg tcagattgat attacagcca ttgatttaga
     3601 agacccgcaa acgttggcac tttttgctaa aggggatacc aagggaattt tccaatttga
     3661 acaaaatggt gctattaatc ttttaaaacg gattaagcca caacgttttg aagaaattgt
     3721 tgccactacc agtctaaata gaccaggggc aagtgactat accactaatt tcattaaacg
     3781 aagagaagga caagaaaaaa ttgatttgat tgatcctgtg attgctccca ttttagagcc
     3841 aacttacggt attatgcttt atcaagaaca agttatgcag attgcacagg tttatgctgg
     3901 ttttacgtta ggcaaggccg acttgttaag gcgtgccatg tctaaaaaaa atctacaaga
     3961 aatgcaaaaa atggaagaag actttattgc ttctgctaag cacctaggga gagctgaaga
     4021 aacagctaga ggacttttta aacggatgga aaaatttgca ggttatggtt ttaaccgcag
     4081 ccatgccttt gcctattcag ctttagcttt tcaattggct tatttcaaag cccattaccc
     4141 ggctgttttt tacgatatca tgatgaatta ttctagcagt gactatatca cagatgctct
     4201 agaatcagat tttcaagtag cgcaagttac cattaatagt attccttaca ctgataaaat
     4261 tgaagctagc aagatttaca tggggctgaa aaatattaag gggttgccaa gggattttgc
     4321 ttattggatt atcgagcaaa gaccatttaa tagcgtagag gattttctca ctagaactcc
     4381 agaaaaatat caaaaaaagg ttttccttga gcctctgata aaaataggtc tgtttgattg
     4441 ctttgagcct aaccgtaaaa aaattctgga caatttggat ggtttactgg tatttgttaa
     4501 tgagcttggt tctctttttt cagattcttc ctttagttgg gtagatacga aagattactc
     4561 agtaactgaa aaatattctt tggaacagga gatcgttgga gttggcatga gcaagcatcc
     4621 tttaattgat attgctgaga aaagtaccca aacttttact cctatttcac agttagtcaa
     4681 agaaagcgaa gcagtcgtac tgattcaaat agatagcatt aggatcatta gaaccaaaac
     4741 aagtgggcag caaatggctt ttttaagtgt gaatgacact aagaaaaagc tcgatgtcac
     4801 actttttcca caagagtatg ccatttataa agaccaatta aaagaaggag aattctatta
     4861 cttaaaaggt agaataaaag aaagagacca tcgactgcag atggtgtgtc agcaagtgca
     4921 aatggctatt agtcaaaaat attggttatt agttgaaaac catcagtttg attcccaaat
     4981 ttctgagatt ttaggtgcct ttccaggaac gactccagtt gttattcact atcaaaaaaa
     5041 taaggaaaca attgcattaa ctaagattca ggttcatgta acagagaatt taaaggaaaa
     5101 acttcgtcct tttgttctga aaacggtttt tcgataaaaa tggacaatta gtgaagtatt
     5161 ttgcaaatga atgtgctata ataagaccgt taaattaatt aaaggagtac cagaaaatga
     5221 aacgtattgc tgttttaacc agtggcggcg acgctcctgg tatgaacgct gctattcgtg
     5281 cagtcgttcg taaagcaatt tcagaaggaa tggaagttta tggtatcaac cgtggctatg
     5341 caggtatggt tgatggcgac attttcccac tgggttcaaa agaagttggt gataaaatct
     5401 cacgtggtgg aactttctta tactcagctc gttatccaga gtttgctcaa cttgaaggtc
     5461 aattggctgg tattgagcaa cttaaaaaac atggtattga aggtgttgtt gttattggtg
     5521 gggatggttc ttatcatggc gctatgcgct tgacagagca cggcttccca gcggtaggta
     5581 tcccaggaac aatcgataac gatattgcgg gaactgacta cactatcgga tttgatacag
     5641 cagttaacac agcagttgaa gctattgata aacttcgtga cacctcatca agtcacggac
     5701 gtacttttgt ggttgaagtg atgggtcgca atgcgggtga tattgctctt tgggcaggta
     5761 ttgctagtgg tgctgatcaa atcattgttc cagaagaaga gtttgatatt gaaaaagtgg
     5821 catcaacaat ccaatatgat tttgaacaca aaggtaaaaa tcaccacatt atcgtcttag
     5881 ctgaaggtgt tatgagcggt gaagcttttg ctcaaaaact gaaagaagct ggcgataaga
     5941 gtgaccttcg tgtgacaaat cttggccaca ttcttcgtgg gggttcacca actgctcgtg
     6001 accgtgtcat tgcttcttgg atgggttcac atgctgttga gctacttaaa gatggcaaag
     6061 gtggtttggc tgttggtatt cacaatgaag aacttgttga aagcccaatc cttggtactg
     6121 cagaagaagg tgctttgttc agcttgactg aagaaggcaa gattattgtt aataatccac
     6181 acaaagctcg tttagacttt gcagctttga accgttcatt gtcacaataa gtttagttaa
     6241 aattgttaaa tcgtcaatta ttgacaaaaa aataagggag tttcagagta aaatgaataa
     6301 acgcgtaaaa atcgttgcaa cacttggtcc tgcggttgaa atccgtggtg gtaaaaaata
     6361 cggagaagat ggctactggg ctggtcaact tgatgttgaa gaatcagcaa aaaaaatcgc
     6421 tgaattaatt gaagctggtg cgaatgtttt ccgtttcaat ttctcacacg gtgaccacaa
     6481 agagcaaggt gaccgtatgg caactgttcg ccttgcagaa gaaattgctc gtcaaaaagt
     6541 tggtttcctt ttggatacta aaggtcctga aatgcgtacg gaattgtttg cagatgatgc
     6601 taaagagttt agctatgtta ctggagaaaa aatccgtgta gcgactacac aaggtattca
     6661 atcaactcgc gatgttattg ctttgaacgt tgctggtagc cttgacatct acgatgaagt
     6721 agaagtaggt catactattc ttatcgatga tggtaaactt ggtttgaaag tgatcgacaa
     6781 agatatcgca acacgtcaat ttatcgttga agtagaaaac gacggtatta ttgctaaaca
     6841 aaaaggtgtt aatatcccta acactaaaat tcctttccca gcacttgcgg aacgcgacaa
     6901 tgctgatatc cgttttggtc ttgaacaagg acttaacttt attgcaatct catttgttcg
     6961 tacagccaaa gacgttgagg aagttcgtga aatctgtcgc gaaactggta acgaccatgt
     7021 gcaattattt gctaagattg aaaaccaaca aggtatcgat aatcttgatg aaatcatcga
     7081 agctgctgat ggtatcatga ttgcacgtgg cgacatgggt atcgaagtac catttgaaat
     7141 ggttccagtt ttccaaaaaa tgattatcac taaagtgaat gcagctggta aagcagttat
     7201 cacagcaaca aacatgcttg aaacaatgac tgaaaaacca cgtgcgacac gttctgaagt
     7261 atctgacgtc ttcaatgctg ttatcgatgg tactgatgca acaatgcttt caggagagtc
     7321 agctaacggt aaatacccgg ttgaatctgt tcgtacaatg gcgactattg atcgtaatgc
     7381 acaaactctt cttaacgaat atggtcgttt agattcatct gccttcccac gtaccaataa
     7441 aacagatgtt attgcttcag ctgttaaaga tgccactcat tcaatggaca tcaaacttgt
     7501 tgtgactatt actgagacag gtaatacagc tcgtgcgatt tctaaattcc gtccagatgc
     7561 ggacatctta gctgtaacat ttgatgaaaa agtacaacgt gctttgatga ttaactgggg
     7621 tgttattcct gttcttgctg aaaaacctgc atctactgat gacatgtttg aagtagcaga
     7681 gcgtgttgct gtggaggcag gcttagttca atctggggat aatattgtta ttgttgctgg
     7741 tgttccagtt ggtactggtg gaacgaatac tatgcgtgtt cgtacagtaa aataaatgtg
     7801 ttataactat ttacctaaag gttagaaggc aatattctaa ccttttttga tatcaaaaat
     7861 atcatgttaa ttcactactg ttaatttact ttaatgagtc taagtttgta ttttatacag
     7921 aatgagtaac gtttattggt attgatcaaa aattgtttac tttttttcta gcttagaaca
     7981 tggtataata agacaataga ctaggagtta atatggtaaa gcgagatttt ataagaaata
     8041 tattattgtt attaattgtg attattgggg ctattttgtt gagaatcttt gttttttcaa
     8101 cttttaaagt ttctccagaa acagctaata cttatttaaa gagtggtgat ttagtcacaa
     8161 tcaaaaaaaa tattcagccc aaatataaag attttgtggt ttatagagtt ggaaaaaaag
     8221 attatgtcag tcgagtcatt gctgttgaag gcgatagcgt gacttatatg gacgatattt
     8281 tttacctcaa taatatggta gagtcacagg cttaccttga aaagatgaaa gcacattact
     8341 tgaatcatgc accgtttggc acattgtata cagatgattt tacagttgct accatcacag
     8401 ctgataagta tcaaaaagtt cctaagggga agtatcttct tttgaatgat aaccggaaaa
     8461 atacgaatga cagtcgtcga tttgggttaa taaatgcctc gcagattaaa ggtttagtga
     8521 cctttagagt tttgcctctc agcgattttg gatttgtaga agtagagtag ttgtcaggct
     8581 actctacttt ttttataatt agactatacc aattttatgt ttgacaagac attgtggata
     8641 ttatatactg taaacataat gtttttatcg gtataattag actataccaa ttattgaaat
     8701 tatgagagaa agtagcaagt taacgaactt gttaaggtaa ttaagatgtg tggaattgtt
     8761 ggagttgttg gaaatcgcaa tgcaacggat attttaatgc aaggccttga aaagcttgaa
     8821 taccggggtt atgattcagc aggaattttt gtggctaatg ccaatcaaac aaacttgatt
     8881 aaatcagtgg ggcggattgc tgatttgcgt gccaagattg gcattgatgt tgctggttca
     8941 acagggattg gtcacacccg ttgggcaacg catggccaat caacagagga taatgcccat
     9001 cctcacacgt cacaaactgg acgttttgta cttgttcata atggtgtgat tgaaaattac
     9061 cttcacatta aaacagagtt cctagctgga catgatttta aggggcagac agatactgag
     9121 attgcagtac acttgattgg aaaatttgtg gaagaagaca agttgtcagt actggaagct
     9181 tttaaaaaat ctttaagcat tattgaaggt tcctacgcct ttgcattaat ggatagccaa
     9241 gcaactgata ctatttatgt ggctaaaaac aagtctccat tgttgattgg acttggtgaa
     9301 ggttacaaca tggtttgttc agatgccatg gccatgattc gtgaaaccag tgaatttatg
     9361 gaaattcatg ataaggagct agttatttta accaaagata aggtaactgt tacagactac
     9421 gatggtaaag agctgatacg agattcctac actgctgaat tagacttatc tgatattggc
     9481 aaagggactt atcctttcta tatgctgaaa gaaattgatg agcaaccaac cgtaatgcgt
     9541 caattaattt caacttatgc agatgaaact ggtaacgtac aggttgatcc ggctatcatt
     9601 acctctatcc aagaggctga ccgtctttat attttagcgg cagggacttc ctaccatgct
     9661 ggttttgcaa caaaaaatat gcttgagcaa ttgacagata caccagttga gttgggcgtg
     9721 gcttctgagt ggggttacca catgcctctg cttagcaaga aaccaatgtt tattctacta
     9781 agccaatcag gagaaaccgc agatagtcgt caagttttag taaaggcaaa tgctatgggc
     9841 attccgagtt tgacagtaac taacgttcca ggatcaacct tatcacgtga agcaacatac
     9901 accatgttga ttcatgctgg acctgaaatt gctgttgcgt ctacaaaagc ttacactgca
     9961 caaattgctg cccttgcctt tttggctaag gcagttggtg aggcaaatgg taagcaagaa
    10021 gctcttgact ttaacttggt acatgagttg tcattggttg cccaatctat tgaggcgact
    10081 ttgtctgaaa aagatctcgc ggcagaaaag gttcaagctt tgctagctac tactcgtaat
    10141 gctttttaca tcgggcgtgg caatgattat tacgttgcga tggaagctgc tttgaaatta
    10201 aaagagattt cttatattca atgcgaaggc tttgcggctg gtgaattgaa acatggaacc
    10261 atttcattaa ttgaggagga cacgccagta atcgctttaa tatcgtctag tcagttggtt
    10321 gcctctcata cgcgtggtaa tattcaagaa gttgctgccc gtggggctca tgttttaaca
    10381 gttgtggaag aagggcttga ccgtgaggga gatgacatta ttgtcaataa ggttcatcct
    10441 ttcctagccc cgattgctat ggtcattcca actcaactga ttgcttacta cgcttcatta
    10501 caacgtggac ttgatgttga taagccacgt aatttggcta aagctgtaac agtagaataa
    10561 atgattataa tggataaggc aaccatctgt taggtggttg ctttttgttt ttaggagaat
    10621 agcagagctt agaaaatggc cttgagaaaa gctatacaag aagaatagtc atcttctgat
    10681 gagaacgtat tcatcttgtc aaatcattga ttctaaagta aaatggtaac attaagaaat
    10741 gtttaggagt gtaagatgtc attaccaaat tgtttgcaat gccagtctga atatgtttac
    10801 gaagatggtc ttttattaat ctgtccaatg tgtgcttttg aatggacacc aggcgaagaa
    10861 gcgactgaag aagaaggact tgttgttttg gatagcaatg gtgtccgact gtctgatggt
    10921 gataccatta ctgtggttaa agatttgaaa gtaaaaggcg ctccaaaaga cctgaaacaa
    10981 gggactcgag ttaaaaatat tcgcctggtg gaaggtgatc ataatattga ttgtaagatt
    11041 gatgggtttg gcgcgatgaa attgaaatca gaatttgtca agaaaatcta ataataatac
    11101 gcaaccagct gatctggttg tatttttata aaaaacctct ccccaaatac gttcaaattt
    11161 ggtataatag tgaaatattc agttttagga ggcaacatga cctatattca gcaagtttta
    11221 cccagcttat tagatggtgc cttggtgact ttacaagtat tctttattgt tatcattctt
    11281 tctataccct taggggctat tttagctttc ttgatgaaga ttccctttaa accgctacag
    11341 tggtttttga ccctatacgt gtggatgatg cgagggacac cattactact tcaattgatt
    11401 tttttctatt atgttttgcc aagtgtgggg attagttttg atcgaatgcc agctgctatt
    11461 ttggcgttta ctttgaatta tgctgcctac tttgctgaaa tttttagagg tgggattgag
    11521 gctattccaa aaggtcaata tgaagcagct aaagtattaa agttaaaacc tcttcaaacc
    11581 attcgttata ttattttgcc tcaagtgttt aaaattgtgt taccaagtgt tttcaatgaa
    11641 gtcattaatt tggtcaaaga ttcttccctt gtctatgtac tcggtgtagg agatctttta
    11701 ttagcaagta agacggcagc caatagggat gcaaccttag cccctatgtt tatcgctggt
    11761 cttatctatt tgcttttaat tggactggtc acgattattt caaaacaagt tgaaaaacgg
    11821 tttaattatt atcagtaagg aggcttcatg ttagaactca aaaatatttc caaacagttt
    11881 ggtcaaaaaa ccatttttga tggctttaat ctaaccgttc aagacggaga agtgctctct
    11941 ttggtaggcc catcaggtgg cggtaagaca acactcttac ggatgttggc tggtcttgaa
    12001 tctattgatt caggtcaagt cttttacaat ggcgaagatg ttggtattga tcatttggaa
    12061 aatcgtaact tgcttggatt tgttttccaa gattttcaat tgtttcctca tcttaccgtt
    12121 ttagacaacc taacgctgtc tccaacaatt acaatgggca agcaaaaggc tgacgctaaa
    12181 gaaaaggctt tggatttact ggcacgttta ggattaaaag aacatgccca agtttatccc
    12241 tattctttat ctggaggtca aaaacaacgg gttgctttgg caagagccat gatgattgac
    12301 cctcaaatta tcggttacga tgaaccgacc agtgctctag atcctgaact acgtcagacg
    12361 gtagaagcct tgattgttca aaaccgtgaa atgggaataa ctcaaattgt agtcactcac
    12421 gatcttgttt ttgccgaagc catctcagat cgtattatta gggttaatcc taaatagaag
    12481 aggacccaaa agatgattat aaaaaaaaga accgtagcaa ttttagccat agctagtagc
    12541 tttttcttgg tagcttgtca agctactaaa agtcttaaat caggagatgc ttggggagtt
    12601 taccaaaagc aaaaaagtat tacagttggt tttgacaata cgtttgttcc tatgggctat
    12661 aaggatgaaa gcggcagatg caaaggtttt gatattgatt tggctaaaga agtttttcac
    12721 caatatggac tcaaggttaa ctttcaagct attaattggg acatgaaaga agcagaacta
    12781 aacaatggta aaattgatgt aatctggaat ggttattcaa taactaagga gcgtcaggat
    12841 aaggttgcct ttactgattc ttacatgaga aatgaacaaa ttattgttgt caaaaaaaga
    12901 tctgatatta aaacaatatc agatatgaaa cataaagtgt taggagcaca atcagcttca
    12961 tcaggttatg actccttgtt aagaactcct aaactgctga aagattttat taaaaataaa
    13021 gacgctaatc aatatgaaac ctttacacaa gcttttattg atttaaaatc agatcgtatc
    13081 gatggaatat tgattgacaa agtatatgcc aattactatt tagcaaaaga agggcaatta
    13141 gagaattatc ggatgatccc aacgaccttt gaaaatgaag cattttcggt tggacttaga
    13201 aaagaagaca aaacgttgca agcaaaaatt aatcgtgctt tcagggtgct ttatcaaaat
    13261 ggcaaatttc aagctatttc tgagaaatgg tttggagatg atgttgccac tgccaatatt
    13321 aaatcttaaa aaggacactt gtcctttttt tgtttaacag gtgagatcta gcagacaaag
    13381 tcagctagac gatttaataa aaatcttagt ttaaggtttt ttattaaact gtattttttc
    13441 tgaaaattat agttttttta aaactgataa atgacaagag aagttatttt aggt
//
LOCUS       DAUGQX010000046        13485 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUGQX010000046 DAUGQX010000000
VERSION     DAUGQX010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13485
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.046"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..962
                     /locus_tag="VIA51_001448"
     CDS             <1..962
                     /locus_tag="VIA51_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8683386.1"
                     /translation="LRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVK
                     DLVSGHLERIQEEVEKKYPDAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIP
                     LTTLFDVINPDFLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAK
                     YQAKGTFFMIGSKVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQHQVNMTNQ
                     AIEKACGKKPRYLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQL
                     QPGGVVLMHDIHQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(1073..2158)
                     /locus_tag="VIA51_001449"
     CDS             complement(1073..2158)
                     /locus_tag="VIA51_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8683387.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFTNIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2256..2882
                     /gene="udk"
                     /locus_tag="VIA51_001450"
     CDS             2256..2882
                     /gene="udk"
                     /locus_tag="VIA51_001450"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEQ8683388.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            2962..3225
                     /locus_tag="VIA51_001451"
     CDS             2962..3225
                     /locus_tag="VIA51_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEQ8683389.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERKLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITCYTSILLTLLVTYIFMK"
     gene            complement(3278..4087)
                     /locus_tag="VIA51_001452"
     CDS             complement(3278..4087)
                     /locus_tag="VIA51_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEQ8683390.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            4232..4729
                     /locus_tag="VIA51_001453"
     CDS             4232..4729
                     /locus_tag="VIA51_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEQ8683391.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFTGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            4729..6399
                     /gene="dnaX"
                     /locus_tag="VIA51_001454"
     CDS             4729..6399
                     /gene="dnaX"
                     /locus_tag="VIA51_001454"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEQ8683392.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVAIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQVNLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            6494..6697
                     /locus_tag="VIA51_001455"
     CDS             6494..6697
                     /locus_tag="VIA51_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEQ8683393.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
     gene            complement(6672..7613)
                     /locus_tag="VIA51_001456"
     CDS             complement(6672..7613)
                     /locus_tag="VIA51_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEQ8683394.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFENGDLQTLRSGEISLSSWEN"
     gene            7817..10195
                     /locus_tag="VIA51_001457"
     CDS             7817..10195
                     /locus_tag="VIA51_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="internalin A"
                     /protein_id="HEQ8683395.1"
                     /translation="MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNMM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            10732..11928
                     /locus_tag="VIA51_001458"
     CDS             10732..11928
                     /locus_tag="VIA51_001458"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ8683396.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEAFESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLVTKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            12102..13361
                     /locus_tag="VIA51_001459"
     CDS             12102..13361
                     /locus_tag="VIA51_001459"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8683397.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT         4293 a         2330 c         2812 g         4050 t
ORIGIN      
        1 acctaagatc agttaacact ttgactattt ctaaaatagt ttatcagaaa aaattttttc
       61 atttggctaa aaaatcagaa aaagttataa gtacatatca cgttacagac gacttgaaac
      121 cgtttcaggt aaaggatcta gtatcaggac atttagaaag aatacaagaa gaagttgaaa
      181 aaaaatatcc agatgctggt tttaatagcg ataagtataa tggcttaaaa gaatctaatt
      241 ctttattaag cgatggcttt gaggtaaaat cgggaaacct tatttttgat aaaaagctaa
      301 cgataccttt gacgacatta tttgatgtta ttaatccaga ttttttagca aatagcgata
      361 gagctgcgta tgataattat aggacctaca aagaacagca tcccaaaaaa ctagttgcat
      421 taacgtttga tgatggtcca gatccgacga cgactcctca agttttagat attttggcaa
      481 aataccaggc taagggaact ttctttatga taggttcaaa ggttgtgaat aatgaaaacc
      541 ttactaaacg tgttagcgac gctggccatg aaattgctaa tcatacttgg gatcatccta
      601 atctgactaa tctttcagtc agcgagattc aacatcaagt taatatgacg aaccaggcta
      661 ttgaaaaagc ttgtggcaag aaacctcgct atttacgccc tccatacgga gctacaaatg
      721 caactgttca gcaatcctca ggattaacac aaatgctttg gacggttgat acaagagatt
      781 gggaaaatca tagcactgat ggcattatga ctaatgtcaa aaaccaattg caaccgggag
      841 gagttgtttt aatgcatgat attcatcaaa caactatcaa tgctttgccg acagttatgg
      901 aatatctaaa agcagaagga tacgaatgtg tgactgtatc agaactctat gcgcatcagt
      961 aagtaatatc gttatgtttc tttagaattg atatactaaa caatccaatt acttttgaag
     1021 taattggatt gttgttttta gtagcccttg attaagtttt gttttttaac aactagttga
     1081 tgaaatgaag ttgttgattt ttgagggaga tttcagagac tttagcaaat tttttcaatt
     1141 ttttgaggtc ttcagggtgg ctaacaaagg taataacgat accagatttt cccatacggc
     1201 cggttcgtcc agctctgtga gtgtaatttt ccttatcacg agcaacatca aaatgaatga
     1261 catagtcaag attatcaata tcaatgcccc gagcaacaag atccgtagct aacaataagg
     1321 agagttggtg ggatttgaat ttttcgagaa tggttttacg gaatttgaca ttaatgtcac
     1381 tcgctaagga aaccgcagca gctccattat attggagacg ttcttccgta gcacccaaat
     1441 cagataaact gttgaaaaag accaaagctc taaaatgagg aatattagta aattttcgta
     1501 ataaatctgt acgttcgcgc ttgtcaacca tgaggtaaaa atgctgaata gcatcgttgg
     1561 tttgctctga aagatcgatg cagaatgtat ttggagctaa ggaagtttga tccaccttat
     1621 tagtagcact catgtatacc atttgatgat ctcgaggaac atagtggcta attttttgaa
     1681 caaaatcata ttgggaatca cctaatagtt cgtcatattc atctaaaaca atggtgttga
     1741 cagacatcat cttgattttt ttcaatttaa tcagctcaaa aatgcgtcca ggggttccaa
     1801 tcaggatttc aggacctttt ttgaggcgtt cgatttgacg tttttgactg gttccagaaa
     1861 taaagagttg tgccgttaag cctagtggct gtgcccaatc ctttgtgact tcaaaaattt
     1921 ggccagctaa ttcggtatta ggggctaaaa tgagtagttg ttgggacttt ttaggcgtca
     1981 gtgccaatag actaggaaag acataagcta aggtcttgcc cgtcccagta gggctaatac
     2041 caaggaaatt tttaccatca acaataggtt gaaaggcctg ttcttggatt ggcgttaaat
     2101 gggtaaatgc aacttggtca agtttttctt gccattgagg gggaaattta gtgatcatgc
     2161 gtcttccttt tactattgtt tctatattca ttatagcatt atagtctcaa ttttggtaaa
     2221 atagtgagaa agacttttta gatttggagt ttaaaatgct taaaaaaccg attattattg
     2281 gtgtaactgg tggttcaggt ggcggtaaaa caagtgtgtc acgcgctatt ttggacagtt
     2341 ttccaaatgc tcgtattgca atgattcaac acgattctta ctataaagat cagtctcaca
     2401 tgagttttga agaaagggtc aagaccaatt atgaccatcc tctagctttt gatacagatt
     2461 ttatgattca gcaactaaaa gaattattag ctggtagacc tgtagatatt cctatctatg
     2521 attacaaaaa gcatacccgc agtaatacga cctttcgtca ggatcctcag gatgttatta
     2581 ttgttgaagg tattcttgtc ctagaagatg agcgtttgcg agatttgatg gatatcaagc
     2641 tctttgtaga cacagatgac gatattcgta ttattcgtcg tattaagcgt gacatgatgg
     2701 aacgtggcag aagcttagaa agtattattg atcagtacac aagcgtggta aagcctatgt
     2761 atcatcagtt tattgagcca agtaaacgct atgctgatat tgttattcca gagggagtta
     2821 gtaatgtcgt tgctattgat gttattaata gtaaaattgc gagtattctt ggagaagtat
     2881 agtggaagtg gctgagtaga ttatttaaat ctgctctttt attgttgtgc tcttcataga
     2941 gaaagggatc ataaaataga aatgttatta atttggcttg gattactatt tgtttggaat
     3001 gaactcgtgt ttgtcatata tgcctttgat aaaagaaaag ccataaaaaa gaaacggcgt
     3061 attagtgaaa gaaaattatt agtgataaca gttttgtttg gaggttttgg agcattactt
     3121 gcagctaaaa agtaccacca taaaaccaga aagtggtact ttgtcatcac ttgttatact
     3181 agtattttgt tgacattact agtaacttat atctttatga agtgagtcac ttaaaagacc
     3241 cttaatcagt attatttagt caaggctctt ttatagttta aaaaagcaca tcatcgtcaa
     3301 gggtgttgat tttttgaaaa agatcaccaa agattaaaag gattaatgtt cctagtaaaa
     3361 ctgtcatgcc aggaatgctt gttagaggag agttccagat gaaatgtaga accagaggac
     3421 ttaataacca gaaaatttgt tgctgttttg aaaaaaggtt agaacccttt aataataagt
     3481 atgctccaat ggtaaaaata gctgtatgta cccaatgtga agtcacagca gtgctaatac
     3541 gttcaatagc agtcggtacg agactatcta tagattttgc ttgaatcaaa taacggatat
     3601 cttctgttag ttgaaagccc atgccagaaa gtaaagcaac aactaatttt tctttaagag
     3661 taagtctagg aaataaagta attactaaaa tagccgaaga agccttaatg ggctcttcga
     3721 caataggggc agttaaagca tctccccaaa gctttaaagc gtctttagaa gggatgatgt
     3781 atgaccaaaa ttgtcctacg agatggttcc cacaagaagc taaaaaacct gaaatataaa
     3841 gtccgctaag acagctaaca ataataacgt tcaggttcat atgaaatttt ttacttaaat
     3901 aaaaaatagc tgctgcaaat ggaattaagt aaatgcctaa tagactaatg gttagtatta
     3961 gagcaaaagc ttctttaaag gaaaggttgt tagcagtcag tcctaacaat tcaagttcaa
     4021 taccatttaa aactaaagca ataaaaagac cgtatcgtaa ccatttctgt tgagtgattt
     4081 gtttcacgaa aacctcctaa tattaagatg atattaataa tattgaaaat tatatcataa
     4141 acaacctcaa aaaccatttt aaaaactgac tgaagcgaaa gatagtcgta aaaaatactc
     4201 gaatagaccc agatatgcta taataaaagg tatgaataag tctaaaaaaa ttgagcaata
     4261 ccaactaatg atagcgcagg caaaagagct gtttgcgaat gaatcaaatg ctttggctaa
     4321 tttgtcaaat gccagcgccc tgttaaacat gacactaccc aattctgttt ttacgggatt
     4381 ttaccttttt gatgggcagg aattaattct tggccctttt caaggtaggg tttcttgcgt
     4441 ccatatcaag cttggtaaag gtgtttgtgg cgaatcagct cagtctcgtc gaaccattat
     4501 tataaatgat gtgaagcagc atgccaacta tatttcctgt gatgcggcag ccatgagtga
     4561 aattgttgtg cctatggtga aagaaggcca tttgattggg gtgctggact tggattctag
     4621 tcttgtagct gattatgatg aggttgatca agaatactta gaggcctttg tggatctatt
     4681 tcttgaaaag accacgttta cctttaacat gtttggagtt aaaaactgat gtatcaagct
     4741 ctttatcgga aataccggag ccaaacgttt gacgaaatgg tgggacaatc ggttatttcc
     4801 acaactttaa agcaggcagt tgaatctggc aagattagcc atgcttatct tttttcaggt
     4861 cctagaggga ctgggaaaac aagtgcggca aagatttttg caaaggccat gaattgtcct
     4921 aaccaagtcg atggtgaacc ctgtaatcaa tgcgatattt gccgagatat cacgaatgga
     4981 agcttggaag atgtgattga aattgatgct gcctcgaata atggtgttga tgaaattcgt
     5041 gacattcgag acaaatcaac ctatgcgcca agtcgtgcga cttacaaggt ttatattatt
     5101 gatgaggttc acatgttatc aacaggggct tttaatgcgc ttttgaaaac tttggaagaa
     5161 ccgacagaaa atgttgtctt tatcttggca acaacggaat tgcataaaat tccagccact
     5221 attttatctc gtgtgcaacg ctttgaattc aaagctatta agcaaaaagc tattcgagag
     5281 catttagcct gggttttgga caaagaaggt attgcctatg aggtggatgc tttaaatctc
     5341 attgcaaggc gagcagaagg aggcatgcgt gatgctttat ctattttaga tcaggctttg
     5401 agcttgtcac cagataatca ggtcgccatt gcaattgccg aagaaattac aggttctatt
     5461 tccatacttg ctctgggtga ctatgttcga tatgtctccc aagaacaggc tacgcaagct
     5521 ctggcagcct tagagaccat ttatgatagt gggaagagca tgagccgctt tgcgacagat
     5581 ttattgacct atctgcgtga tttattggtg gttaaagctg gcggcgacaa tcaacgtcag
     5641 tcagctgttt ttgataccaa tttgtctctc tcgatagatc gtatattcca aatgataaca
     5701 gttgttacta gtcatctccc tgaaatcaaa aagggaaccc atcctcggat ttatgccgaa
     5761 atgatgacta tccaattagc tcagaaagag cagattttgt cccaagtaaa cttgtcagga
     5821 gagttaatct cagagattga aacgctcaaa aatgagttgg cacaacttaa acaacaattg
     5881 tcgcagctcc aatcgcgtcc tgattcactg gcaagatctg ataaaacgaa acctaaaacc
     5941 acaagctaca gggttgatcg ggttaccatt ttgaaaatca tggaagaaac ggttcgaaat
     6001 agccaacaat ctcgacaata tctagatgct ctaaaaaatg cttggaatga aattctagat
     6061 aacatttctg cccaagacag agccttattg atgggctctg agcctgtctt agcaaatagt
     6121 gagaatgcga ttttggcttt cgaggctgcc tttaatgcag aacaagtcat gagccgaaat
     6181 aatcttaatg atatgtttgg taacattatg agtaaagctg ctggtttttc tcccaatatt
     6241 ctggcagtac caaggacaga ttttcagcat attcgtaagg aatttgctca gcaaatgaaa
     6301 tcgcaaaaag acagtgttca agaagaacaa gaagtagcgc ttgatattcc agaagggttt
     6361 gattttttgc tcgataaaat aaatactatt gacgactaaa actgaaatac ataagggtaa
     6421 ggttttgccc ttacccacgt tttatctcgt tacttttctt catagtacag tatttttttg
     6481 ttataataaa gctatgacta ttcgacaatt tctttttatg gcctttgtat gtgcctttga
     6541 aacctatttt tttaatgacc tgttactctc tggaaattat ctcttcgcct tattttgggg
     6601 cttgttgctc tttagggatt taagaagagt gcataccatt aaccaactga ctaaaaccat
     6661 tttaaaaacg gctaattctc ccaagaagaa agactgattt caccgcttcg caaggtttga
     6721 aggtcaccat tttcaaactg tacaatgagg tgtccttgat ctgtgagatc aatcgcaata
     6781 gcacgttttt cttgactatt ttctataaag gtcacttgtt tattaagaac aagtgatttt
     6841 tctttgtaaa ctttgacatg gtccttgaca ggaatagata agaataattt ccagatgtca
     6901 atgataaggt cattgcgcgt gatagtcggt ttttcggtaa agagagaacc tgccttttga
     6961 gcaatcgctt ctgggaagtc ggtgacaaaa aagttgagac caaccccaat aatgacatcg
     7021 gtgattaaac cagtttcaac agaagtaatg gcttctgtca gaatccctgc aactttatgg
     7081 ttacctagat agatgtcgtt tacccatttg atttctgtat caatgcctgt taatcgcgag
     7141 atagctttga caatactgga agcaaccatc atcgtataag gaggcatatc agcataaggg
     7201 acattgggtt ttaggtacat ggacatgtaa ataccaccgg tgctagctga aaaaaattgc
     7261 cgatcgaggc gtcctttggc agcttcttgg ctaggagcta ggtaaagcct tggagcgctg
     7321 ttatgagctt cgattccttg tttggcatct aattgggtag attggctgtg aggggtatag
     7381 gtgactggca tcccaagccc ttggctaatg gttttgggta ataaaatatc accttgtacc
     7441 atgcggtagc ccttgtgttt taaagaatca atttgaatcc cctgattttc gagacttttg
     7501 atggatttcc aaacggatgt acgagagata ctgagttgat ctgctagata ttccccactg
     7561 acgaagtcat cggtttgtga cagtaattga taaatttttt ctgatgtttt catatgtata
     7621 gtatattata aaagatctta ttttcaaagg aaaagaaaag ttagtttttt tgtgtaatgc
     7681 tactaacaac agaaactatt gtttgttgaa gcttcagagc tccaactcgt caacaactaa
     7741 tagttatcct aaaaagagct tgaggaaaaa caagtgatgt gatatactta accagttaaa
     7801 taaaaaggag ggttgaatga aaacgaaaaa agttattatt ttagttggtc tattgttatc
     7861 atctcagttg actttgatag cttgtcaatc acgaggtaat ggtacatatc ccattaaaac
     7921 gaaacaatca cgtaagggaa tgacgtcaaa caaaattaaa ccgattaaaa aaagcaaaaa
     7981 gacaaacaag actcacaaag gtgtggcggg tgtcgatttt cctacagatg atgggtttat
     8041 tttaaccaaa gactcaaaaa tcttatcaaa aacagatcag ggaatcgttg ttgaccatga
     8101 tggtcattcg cattttattt tttatgccga tttaaaggga agtccatttg aataccttat
     8161 tccaaaagga gcaagtttag ctaagccagc tgttgctcag cgagcagcta gtcaagggac
     8221 ttctaaagta gcagatcctc atcaccatta tgaatttaac ccagcggata ttgtggctga
     8281 agatgcttta ggctacacgg ttcgccacga tgatcacttc cattatattt tgaagtcaag
     8341 cttatcaggt cagacacagg cacaagctaa acaggttgct actcgcttgc cacaaaccag
     8401 tagccttgtt tcaacagcta cagctaatgg tattccaggc ttgcatttcc caacctcaga
     8461 tggttttcaa tttaacggtc aaggtattgt tggggtaaca aaagacagta ttttagtgga
     8521 ccacgatggt cacttacatc ctatttcttt tgcggacctt cgtcagggtg gctgggcaca
     8581 tgtggcagat caatacgatc ccgctaaaaa agcagaaaag ccagcagaaa cccatcagac
     8641 accagagcta tctgaacgtg aaaaggaata ccaagaaaaa ttagcttatt tggcagaaaa
     8701 attggggatt gatccatcaa ctattaaacg tgtggaaaca caagacggta aacttggttt
     8761 ggaataccct caccatgacc acgcacacgt attgatgtta tctgatattg aaatcggaaa
     8821 agacattcca gatccacatg ctattgagca tgcccgtgaa ttggaaaaac ataaggttgg
     8881 aatggatacc ttgcgtgcct tagggtttga tgaagaagtg attttggata tcgttcgcac
     8941 tcacgatgct ccaaccccat tcccatcaaa tgaaaaagat ccgaatatga tgaaagaatg
     9001 gttagcaacg gttatcaaac ttgacttggg cagccgtaaa gatcctttgc aacgtaaagg
     9061 actttcactg ttacccaact tagaaacttt aggaattggc tttacaccaa tcaaagatat
     9121 ctcacctgtt ttgcaattta aaaaattgaa acagttgtta atgacaaaaa caggggtgac
     9181 tgattataga tttttggata atatgccaca gttagaaggc attgatattt cacaaaacaa
     9241 tctcaaagat attagtttct tgagcaaata taaaaactta actctagtag cggctgctga
     9301 taatggtatt gaagatatta ggccgcttgg tcaattacca aatctcaaat tcctcgtatt
     9361 gagtaacaat aagatttctg atttaagccc actggcatcg ttacatcaat tgcaagaatt
     9421 gcacattgat aataatcaga ttacagattt aagccctgtt tctcataaag aatcattgac
     9481 ggttgttgat ttatcaagaa atgctgatgt tgacttagca acacttcaag cacccaaatt
     9541 agaaacgtta atggtcaatg ataccaaggt ttctcatttg gatttcttga aaaataatcc
     9601 taatctatct agcctatcta ttaaccgtgc gcaattgcaa tctcttgaag gtattgaagc
     9661 aagtagcgtc attgtcagag tagaagcaga aggtaaccaa attaaatcgc ttgtgcttaa
     9721 agacaagcaa gggtcactta ctttcttgga tgtgacaggc aaccagttga cttctctaga
     9781 aggtgttaat aattttacag cacttgacat tttaagcgtg tctaaaaacc aattaacaaa
     9841 tgtcaaccta tctaaaccca ataagacagt tactaacatt gatattagtc ataacaatat
     9901 ctcattagca gaccttaaat tgaacgagca acatattcca gaagccattg cgaaaaactt
     9961 cccagcggtt tacgaaggtt ctatggtagg taatggaaca gctgaagaaa aagcagctat
    10021 ggctactaag gcgaaagaaa gtgctcaaga agcatcggaa tcacatgact acaaccataa
    10081 tcatacctat gaagatgaag aaggtcatgc tcacgagcac agagacaaag atgatcacga
    10141 ccatgaacat gaggatgaaa atgaagctaa agatgagcaa aaccatgctg actaaactaa
    10201 tctaagaata acccgatcca actgaatcgt cctaatgaca ccattgttga ctatcaagag
    10261 aacctcaaga ataaccttga ggtttttttg aaataaatag gataatgagt gaaaagaatg
    10321 gcacctaaat ggctaaaaca tgttataata gattgttatt gagtcccgat aagacggtct
    10381 gttgaacgaa atgtttttga gacgttgttg acttcatttg gggaacagtc gttctccctt
    10441 tagctaaatt acttcgtcta aggcttattt tgtggtgaca tcctctcaac aaggagaccg
    10501 gattctttgt aactcaacgc tattgtcaga cattctttgt ctggttaatg gacgctagcc
    10561 actaggtgga ctagctagtt gccttactag taaaaccgta actgattagc taagttggtt
    10621 ttggccactt gacttgctca atcagctagg aagaaagggg taggcaactt cttgctttgt
    10681 ggtcaatgtg actgaaaaag gaagaatcaa catattaggg gggacatttt tatgtcagaa
    10741 cgtaaacttt tcacgtctga gtccgtatct gaagggcatc cagataagat tgcagaccaa
    10801 atttcagatg ctattttaga tgccatttta gcagaagatc cagaagccca tgtggctgca
    10861 gaaacttgtg tttacacagg ttctgttcat gtttttggag aaatctcaac aacagcatac
    10921 attgatatta accgtgtggt ccgcgacacc attgcagaaa ttggttatac agaagcagaa
    10981 tatggctttt cagcagaatc agtgggagta catccatcac ttgtagaaca atctggagat
    11041 atcgctcagg gggttaatga agctttcgaa agcagagaag gtgatactga tgaccttagc
    11101 catattggag cgggtgacca agggctcatg tttggttttg ccatcaatga aacaccagaa
    11161 ttgatgcctt taccaatttc cttatctcac caattagtgc gtcgcttggc ggaattacgt
    11221 aagtcaggtg agattagtta tctacgtcca gatgctaaat ctcaagtgac agttgagtac
    11281 gatgaacacg ataaacctgt tcgtgtggat acagtcgtta tttctactca gcatgatcca
    11341 gaagctacta atgaccaaat tcgtcaggat gtgattgaaa aagtgatcaa ggctgtaatt
    11401 ccagcagatt atttagatga tgacacaaag ttcttcatta atccaacagg acgttttgtt
    11461 attggaggtc cgcaaggaga ctctggattg accggacgta agattattgt ggatacctat
    11521 ggaggctatt cacgtcatgg tggcggtgct ttttcaggaa aagatgcgac aaaagtggac
    11581 cgttcggctt cttacgctgc tcgctatatt gctaaaaacc ttgtggcagc aggccttgtg
    11641 accaaagctg aagtccaact agcttatgcg attggggtgg ctcagcctgt gtctgttcgc
    11701 gtggatacat ttggaacctc aacggttcct gaagctgttt tagaagctgc tgttcgtcaa
    11761 gtctttgatt tacggccagc aggcattatt caaatgcttg atttaaaacg cccgatttac
    11821 aaacaaacag ctgcctatgg tcacatgggg agaacagata ttgatttgcc atgggagcgt
    11881 ttaaataagg ttgatgcttt agtagaagct gtaaaaacag tattataaac gacaacttta
    11941 ttaaaaaagt agagtaagtg aaaaaatctt actctgcttt tttgttatta aataagcctt
    12001 taaaagggat gattaaaaat taagacgtca ataattgtca ggcttcatga tttatgataa
    12061 aatgaaaagg ttgaattcta gtataagaaa gttttgaatg tatgcgtaaa attattatta
    12121 atggcggaaa agccttatct ggagaagtgg cagtttcagg ggcaaaaaac agtgttgttg
    12181 cgcttattcc agcaatcatc ttagccgatg atattgtgat tcttgatggt gtacctgcta
    12241 ttagtgatgt agatagtctg attgaaatca tggagcttat gggagcaaca gtaaactatc
    12301 atggtgatac tttagaaatt gaccctagag gggtgcaaga catcccgatg ccttacggaa
    12361 agattaatag tcttcgagct tcctattatt tctacggtag tcttttaggt cgttttggac
    12421 aagcagttgt tggcttacct ggtggttgcg atttaggacc aagaccaatt gacttgcatt
    12481 tgaaggcctt cgaggctatg ggagttgaag tgtcttatga gggtgaaaat atgaatttat
    12541 cgacaaatgg tcaaaaaatt catggcgctc atatctatat ggacaccgtt agtgtcggtg
    12601 ctacaattaa tactatggtt gcggcaacaa aagctcaagg taaaacggtt attgaaaacg
    12661 ctgcacgtga gccagagatt attgatgtgg ctactctttt gaataacatg ggtgcgcata
    12721 ttcgtggagc aggtacagat attattacga tacaaggtgt tcagaaattg catggtacta
    12781 gacaccaagt tattcctgat cgtattgaag cagggactta tatcgctttg gcggcagcta
    12841 ttggaaaagg tgttaagatc actaatgttc tttatgagca tttagagagt ttcattgcta
    12901 agttagaaga aatgggtgtc cgtatgacgg tagaagagga tgctatcttt gttgaaaagc
    12961 aagaatccct caaggctatt acaattaaaa cctctcctta ccctggtttt gccactgatt
    13021 tgcaacagcc attaacgccc ttgttgttaa aagcagatgg tcgtggaacg attattgaca
    13081 ctatatatga aaagcgcatt aaccatgtgc cagagttgat gcgcatggga gcagatatct
    13141 cagttattgg tggtcaaatt gtttatcaag ggccgtctcg cctgacagga gctcaggtca
    13201 aagccactga tttacgtgcc ggagcggctc tagtgactgc tggtctaata gctgaaggca
    13261 agacagaaat tactaatatt gaatttatct tacgtggcta tgctagtatc attgcaaaat
    13321 taacagcact aggggcagat attcaattaa tcgaagacta aagagaagct aacgcttctc
    13381 ttttttatat tacatgtgct taggctaatg atacttaggt gcatactttg ttgcatttta
    13441 tggcttttta actgtcataa aaaagataaa aatgatatca ctaac
//
LOCUS       DAUGQX010000047        13350 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUGQX010000047 DAUGQX010000000
VERSION     DAUGQX010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13350
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.047"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            27..2201
                     /locus_tag="VIA51_001460"
     CDS             27..2201
                     /locus_tag="VIA51_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8683398.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPTKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            2201..2941
                     /locus_tag="VIA51_001461"
     CDS             2201..2941
                     /locus_tag="VIA51_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683399.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(3089..3241)
                     /locus_tag="VIA51_001462"
     CDS             complement(3089..3241)
                     /locus_tag="VIA51_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683400.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(3238..4617)
                     /locus_tag="VIA51_001463"
     CDS             complement(3238..4617)
                     /locus_tag="VIA51_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8683401.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(4795..5244)
                     /locus_tag="VIA51_001464"
     CDS             complement(4795..5244)
                     /locus_tag="VIA51_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEQ8683402.1"
                     /translation="MIISAEGDVSIHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYQLEALGENRTRITYSYD
                     YHPLDIFQKANQFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(5241..5576)
                     /locus_tag="VIA51_001465"
     CDS             complement(5241..5576)
                     /locus_tag="VIA51_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8683403.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(5579..5890)
                     /locus_tag="VIA51_001466"
     CDS             complement(5579..5890)
                     /locus_tag="VIA51_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8683404.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EMAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(5913..7907)
                     /locus_tag="VIA51_001467"
     CDS             complement(5913..7907)
                     /locus_tag="VIA51_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8683405.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTIRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVVICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(8013..9107)
                     /locus_tag="VIA51_001468"
     CDS             complement(8013..9107)
                     /locus_tag="VIA51_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEQ8683406.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIAPS"
     gene            complement(9116..10516)
                     /locus_tag="VIA51_001469"
     CDS             complement(9116..10516)
                     /locus_tag="VIA51_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8683407.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLISEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSNAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDLLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            10741..11436
                     /locus_tag="VIA51_001470"
     CDS             10741..11436
                     /locus_tag="VIA51_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEQ8683408.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILITLIFYSILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYNWL
                     MLQRYQEKKVKKG"
     gene            complement(11441..11599)
                     /locus_tag="VIA51_001471"
     CDS             complement(11441..11599)
                     /locus_tag="VIA51_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683409.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(11668..12981)
                     /gene="obgE"
                     /locus_tag="VIA51_001472"
     CDS             complement(11668..12981)
                     /gene="obgE"
                     /locus_tag="VIA51_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEQ8683410.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDIPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD"
     gene            complement(13038..13166)
                     /locus_tag="VIA51_001473"
     CDS             complement(13038..13166)
                     /locus_tag="VIA51_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEQ8683411.1"
                     /translation="MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM"
BASE COUNT         4049 a         2848 c         2429 g         4024 t
ORIGIN      
        1 ttttttagtt ttataaggag attagtatga cgcacaaaat aaaagtattg ctgcttgcga
       61 taatgtctat ttttttgaca tgcaatattg caagtgctga aactattgct attgtttcag
      121 atacagctta tgccccattt gaatttaaag actcagatca aatttacaaa ggaattgacg
      181 ttgatattat taatgaagta gccaaacgtc aatcttggga tttcagtatg agtttcccgg
      241 gttttgatgc agctgtaaat gctgttcaat ctggtcaagc gagtgctcta atggccggta
      301 caaccattac gaatgctcgt aagaaagtct ttcatttctc agagccatat tacgatacca
      361 aaattgtcat tgcgacacgt aaagccaatg ccatcaaaaa atacagtgac ttaaaaggaa
      421 aaacggtcgg tgttaaaaat ggaacagcgg ctcaagcctt tttgaataac tataaaaaaa
      481 agtatgatta tactgttaaa acatttgaca caggtgatct tatgtataat agtttatctg
      541 ctggttctat tgccgctgtt atggatgatg aggcggttat ccaatacgca atcagccaaa
      601 accaagatat tgctattaac atgaaaggag agcccattgg aagctttggg tttgctgtca
      661 aaaagggaag cggatatgat tatctagtta atgatttcaa tacagctctt aaagctatga
      721 aagctgatgg tacctaccaa gctatcatga ccaagtggtt aggcacagat gataaagcta
      781 ccaccagtca ggcaacggga aatccatctg ccaaagctac acctacaaag gacagttata
      841 aaattgtctc tgattcgtct tttgcacctt ttgaatttca aaatggtaag ggcaaatacg
      901 ttggtattga catagaatta atcaaagcta ttgctaaaca acaaggtttc aaaattgaaa
      961 tcgctaatcc aggtttcgat gctgccttaa atgctgtgca atctagccaa gcagatgggg
     1021 tcattgctgg tgcaactatt actgacgctc gtaaagctat ctttgatttt tctgatcctt
     1081 attatacttc taatatcatt ttagctgtta aagctggaaa aaacatcaag aactatgaag
     1141 acttagacag aaaaacagtc ggtgctaaaa acggcacttc atcttactct tggttaaaag
     1201 aaaacgctcc taaatatggt tataatgtca aggcatttga tgatggttct agcatgtatg
     1261 atagcttaaa ttcaggttct gtagatgcta tcatggatga tgaggcggtt cttaaatacg
     1321 ctatctctca aggtcgtcgc tttgaaacac ctcttgaggg catttctact ggtgaagttg
     1381 gttttgctgt caagaaagga actaatccag aattaatcga aatgttcaac aatggcttag
     1441 ctgctctcaa aaaatctggt cagtatgatg acattataga taaatacctt gactctaaga
     1501 aagctgcaac tccttctgaa aaaggtgctg atgagtctac tatttcaggc ctattatcaa
     1561 ataactacaa acaactattg gcaggacttg gaaccacgct cagtttaacc cttatttcat
     1621 ttgctattgc tataattatc gggatcatct ttgggatgat ggccgtgtca ccaactaaat
     1681 cacttcgact tatttcaacg gtctttgtgg acgttgttcg agggattcct ttgatgattg
     1741 tggctgcctt cattttctgg ggagtaccaa accttatcga gagtatgacc ggccaccagt
     1801 caccgattaa tgatttctta gctgctacaa ttgcactgtc acttaatggc ggagcctata
     1861 ttgctgaaat tgttcgcggt ggtatcgaag ctgttccagc agggcaaatg gaagctagtc
     1921 gaagtcttgg tttgtcttac ggaaccacga tgagaaaagt aattctccca caagctgtga
     1981 aactaatgtt acctaacttt atcaatcagt ttgttatttc attgaaggat acaacaatcg
     2041 tctcagcaat tggtttagtg gaactcttcc aaacaggtaa aatcattatt gctagaaatt
     2101 accagtcgtt ccgtatgtat gctattttag caattattta ccttatcatg attacactct
     2161 taacaagact tgcaaaacgt ttagaaaaga ggcttaacta atgacagaat taaaaattga
     2221 tgttcaagat ttacacaaat cttatggtca aaatgaagtc ttaaaaggaa ttgatgccaa
     2281 attctacgaa ggcgatgtcg tttgtatcat tggtccttct ggttctggga aatcaacctt
     2341 tctacgtacc ctcaacctcc tagagacgat taccagtggt aaggtcatgg tggacggttt
     2401 tgaattatca gatcctaaga ctaatattga caaggcacgt gaaaatatcg ggatggtatt
     2461 ccaacacttc aaccttttcc ctcacatgac tgttcttgag aatattatct ttgctcctgt
     2521 tgaattaggt aaagagtcta aagaagttgc taaaaagcat ggcatggcac ttctagaaaa
     2581 agtcggactt tctgataagg ccgacgcctt cccaggaagt ttatccggcg ggcaaaaaca
     2641 gcgtgtcgcc atcgccagaa gtttagcaat gaacccagat attatgctct ttgatgaacc
     2701 aacttctgct cttgaccccg aaatggttgg ggacgttttg aacgttatga aagacttggc
     2761 agaacaaggc atgaccatgt taattgttac tcacgaaatg ggatttgctc gccaagtagc
     2821 taaccgtgtt atctttacag acggtggtca attcttggag gatggtactc ctgaagagat
     2881 ttttgatcat cctaagcacc ctcgtctcat tgaattttta gacaaggtct taaacgtcta
     2941 atagagcaga caccatacta acttccaaaa aataataagg caaggaaaca ggtttccttg
     3001 ccttttttgg ttactgttat tattcaaacc agcaaaatag ggatactctt atgactctct
     3061 ccttcataag agtgtcccct atgctttttt atgggcgttt atgtttagtg aggtaataac
     3121 ctaatcccgt aagagctagt cccgtcacta tgtgtaagta tttgttacca accatcggac
     3181 taatggcaat gagaaaaaag ccaacagcca ttaaaaaagt tgctccattt ttttctgtca
     3241 tgcaaggtca ctcgcttttt ctttattggc caaaatgaca aatggtgccc agataaggaa
     3301 ggcaacaaag aggttaaaca gtgaaaccaa acctgccata atattacctc cagtagctag
     3361 gtaagcataa agtccaacag gggtaatcca aggtactgat aagaataccg gtggaatcaa
     3421 acctattgca gtagcaaaat aagctatgct agcacaaatt ggtggcacaa ttagccatgg
     3481 aatcacaaag gttggattca aaacaattgg catcccaaat gtaattggtt cgttgatatt
     3541 gaaaacaccc attggtgcgg acaatttggc aatggtttta tgctcttctc gttttgagaa
     3601 tatgaagata gcaataatca atgccaaggt tactcctgaa ccacccattt gagcataagc
     3661 atcaaaggac ccgcgtgtcc aaaggtatgg taaattagca gcgctatgcg ctgtattgta
     3721 agcagctgta ttttctgtta aagctaccat ataaatacca tccatcactg gggctaagac
     3781 attatgacca tgcaagccga agaaccagag cagttgaact aagaaggtta acaagataac
     3841 tgaaccaata ccctgtgata agcctagcaa tggtaattgg atataggttg aaatgacatc
     3901 acttagggaa gaacctgtta atgcgaaaat gaggtaggcg aaaattgccg aagcgtaaat
     3961 cgcaactgtt cctggaataa tggcagcaaa ggctttatta accgcaggtg gtacattatc
     4021 tggtaaggta atggtaatat tacgtttggt caaagccgca tacacaaaac ttgataaaaa
     4081 gccaataatt aaagctgtga acaagcctgt ggcaccgaca tactttagag ctattgctcc
     4141 ccattgacta gtttcaatac ttgaagctcc acccgcagta acgactgaaa gccccatttc
     4201 tttcaaattg ctaattaggt tagcagaggc attttcaagt ggtgtcgaaa tggttaaagt
     4261 ctgaggtagg gtggcaataa atgagccaaa agaaatcaat cctcctgcca atggattaat
     4321 cttatgcata acagctaaat tgtaaccgaa agcaaaggca aaaaagagcg ccatgatacc
     4381 aattgtccca aaataaacat agccattgat gtcgataaca ggttgcatag cttttgcaaa
     4441 tcctgtccat cccatattgt ttggaatatc gcgtaaaaaa acgttcaata agacagcaac
     4501 tgaacctgcc atggtaatag gcatcattga aataaaggaa tcacgaatag ctactaaatg
     4561 ccgttgtgac ccaatttttc ctgaaatctc cataaactta tcagaaaaat gcgacataaa
     4621 tcttctcctc tttttatttt tttaatgtaa caaaggtaac cttaaaagca gcggtgtctg
     4681 cctaacacaa ttatctcaaa atcatccttg ttaaacgtga tgcttagaga taaccggtaa
     4741 tcggctctta tccaaatgaa cccttctctc tcattcaagg tctgtgaata atcttcacaa
     4801 agacgatggt tgctgcaact gtttagcata ttggataagg gctgctaact gagcttgaga
     4861 ttggcgttct aggctttttt tgaacagttt gccaacaata aattgatttg ctttttgaaa
     4921 aatatctaga ggatgatagt cataagaata ggtaattcta gtccgattct cccccagagc
     4981 ctctaattga taagccaatt cctttatccc atgattggaa ctaaaacaag cagtatataa
     5041 ttgcggagct tctagggccg taataagcac cctcactgta cgttctttgt atttaccata
     5101 atgtttaaca tagtttatcc ccgctttgat atcatctctt gacaactgtc tcaaggtatt
     5161 ttgtcgataa tcttcttgga gcgatatcag catggcttca aaacaatgat gaatggaaac
     5221 atctccttct gctgaaataa tcatgactca cctctttgta ttgctgacat tttgtcgtaa
     5281 acggtaacca attccttggc taaatcaata aaggctaagg cagtcatcat gtgatcttgc
     5341 ccatgcacca tcaataaaga caattcaacc gcatcaccag ctgcttcttg ggacagcaaa
     5401 tgtgtctgcg atttatgggc aatatttaac gagtttgtcg cttcttgaag taagtgctga
     5461 gcctcctcaa actgcccatc tcgtgctgca tgaatagcct ctacggcctt gcccttggct
     5521 tcgcctccat acatgattaa gcccataata gcttctaagt tggatggttc cgtcatgcct
     5581 actcctccat cattgctagg gctgtttcaa ggactttttc accgttcata agaccataat
     5641 cagccatgtt aatggcatct actttaatat ctggttcaaa cttatcttta aaatccttta
     5701 gtaagaattt gacttgtgga cctaacaaga gaacgtcaat gctattagca gccatttcgt
     5761 tgtcagcttc actcacagga actgcccaaa tagaaacttc aaggtcacgc gcttgggctg
     5821 ctttttgcat cttagtcacc aacatactag ttgacatacc ggcattacaa actaacataa
     5881 tagatttcat aaggtttctc cttttaatcg ttttaatcat gaataagtgg ggtaaacact
     5941 gtcatgaatt tggaataatt tggttcttct agtaacgctt gctgaagctc cacctgattg
     6001 acaaaagatg ccaaacctgg tgatacatat tttaacctat gattatgccc tttagacggg
     6061 gataatagaa agacaaaatg aacagcttga tgcgccttgt cccactcaag aggctctcgg
     6121 caaataacca ctactacctg ttcagaataa gtcatgggat tagcaggatg cggaaaggca
     6181 agcacttctc catagatgac tgggctgtaa ttttccctca gtaccatttg atgatagaag
     6241 tcctctacaa acgtttctgt tcccgcctcg tcaagacaag caatcatccg taaaagcaag
     6301 tcttcctttg agattttctc gtctaaataa agaaaacgat tagggctaaa aacacctgtt
     6361 agaagctgct ctgcttttgc taaactcatc tgtgacggta aactgacctc tttcttgata
     6421 ccttcttgtt ctccaataaa ttgtcgaata gtttcaatat cctgatttga caaaaaaaca
     6481 ctgacagtaa tcactggtgt taaaaacatc agattggcaa ggctgataga ggaaataatc
     6541 aaatcaacgg ttttcagtcg ctcttcggtt atttcatagt aactgataac atcgacaata
     6601 cgcaaacgtc cttcaaattc cttttccaag cgatttttca acatcatggc actaccataa
     6661 cctgtggcac aaactactag aaccctcaat ttatgacggt ttgaataacg ctcaatggcc
     6721 gccattaaat gcaaactaat ataagcccat tcatcatctg agacatcatt cttttgacat
     6781 acaagcaaat ccgaaaaggt ctgcttggta agggtaaata tttcaggata ctggctttta
     6841 atttcctcag ttaaaggatt agtcagctga atatggtttt caagacgtat ggtcaagggc
     6901 atcatgtggg ctaataaacc ttgaaataaa ttggtatctg tttctaaagt catgcctgtc
     6961 aattgactaa tcttggcaat acatgctttt aaatggtcct gcaacttttc atcggtatta
     7021 tcatcttgcc aatgcttacc aacagaatgt ttgaccttta gatgcagtgc aatataatta
     7081 gcctcctctt taggaaaacg tatccccatc acttcttcca ctcgatacaa aatgcgcaga
     7141 gctacttgat actcatcaga ctgacgaata gctattggaa tggaaaacag ttctaatgga
     7201 caccccgatc gaatacgctg aaccattagg gcaatatgca agactagatt attcatgaca
     7261 aaatcagaaa gtttcaactt agcatcccga cattcatcca agacaataat catgatttct
     7321 gcaaaattaa taccttcaag aaaggtatta cctaccatgg tggacaaggt attatcaaaa
     7381 ctagtaacaa aaaaatagtc catgataaaa tgcctaatgt cctcttcttt acctcttatt
     7441 tgaatatgtt ggtgagttat ttcaagctct aactggtaag gtattatgcg ctccttaata
     7501 cctgctaaaa catgttttaa agttgtccga ctgatataca attcttgaca aagctcttca
     7561 aaatcctgaa cggcatcttc aaaaaagaat ttatgaagca cataatcttc tcgatcaacc
     7621 gattcttcca cttgagtcac atctgccaaa cgttttttag acgtcacact ttcttgccaa
     7681 aagatgtcaa atgccataga atggtcaatt tctaagcagt aacctcgacc ttgtttagaa
     7741 atgatgtgag ctccgtgttc aggaaggcta ctgatcagtt ctttgaggta tttcctaacc
     7801 gtacggtcac tcataccgat aacctcagcc agagttgcac tagagacaaa ctgctctttg
     7861 tgatggatta gaaatgttat gatggccagt tctttttttg ataacattag tcctccttac
     7921 tactttagaa aacgctttct accctccttt agtgtaccaa atatttcctg aaaaaggtga
     7981 ccatcatttt ccgcattgat tgtgaaaaga atctatgatg gggcaatctc caaacaaaat
     8041 tcctgccaag gtcgcaaatc atctaacaaa ctaagatagt cctctctgac ctcagcaacc
     8101 acattagctt ttgaactgac cgtaaaattt ttcaaagcaa tttgcagttc tcccttatat
     8161 cgatgatagc ggtcattgtc aataataatg ctacctcgtt tgacctcctt agattggtct
     8221 cttggagcaa tcgattcctg agcatagact agacgtggca tggttgatcg aatcacataa
     8281 tcagatacat cgccacgata acaatgcgga tagccaatga tttgctcctc aacttctgtc
     8341 aaatcgatga taggcctaac cttgatcgtc gtgactggtc ttgctaaagc ttgagtacat
     8401 gctgccaatt cttcttccga aatgaattgg ttagatatga ggatattatc aatggttcct
     8461 atcgctttca ttaattctac ttgcaggcca atgggcaagt gcctatggtc ttccactgtc
     8521 ggcaagcctt ctgccagtag ccaagggcct tcagatgctg actgagcggt aataaaagca
     8581 gccgtttcaa tatcatgctc atgataaaaa cgtgacatat ccttaaaatg ttgccatgac
     8641 aaaccggtaa attcatgtgg ataaaaatta tggcaaccaa taatattgct ccgttctgca
     8701 tctgtcgcta gcaatgacat caataattgt ttatcagtgc tcatattaag ttcaatttta
     8761 agcccaaagg gatttcttgt taaagttaca atctctgcta gagggagagc ctcgtctaag
     8821 cgtaagcccg ctaacccgaa ggcatgagct cgttcaataa gctgatctga ccaaccagct
     8881 tggctaataa agcttggact aacgtcagca atcactcgaa tgcctaattg atttgcataa
     8941 gcaatgagct ctgcgtagca atgaaacatc tggtgatcag ctggtgccag ctgtaagaga
     9001 ctcataaaca agcgcttggc tccatagcta tgacataagt caatataagc tttactcttg
     9061 gtaacatcat accgctcagg gtatagagaa aatcctaaat caaccatatt gcctcctatt
     9121 tatcaaaacc atttgactcg ctcaacgcct taaaccagta acctgatttt tttatggttc
     9181 gcttttgact ctctaaatcc aaagctacca aaccatatcg gtttttataa gcatttaacc
     9241 aagaccagca atcaataaaa gtccacaaga ggtagccttt gcagttggct ccttctccca
     9301 aagccttatg aagctggata agatgatcct cgataaaggt gatgcggtag tcatcttgta
     9361 tctggccatc tgctaaaaaa gcttcttcac cttcgacacc cataccattt tccgtgacta
     9421 gccattcgat gttaccatag tgttctttta aattaagggc aatatcataa agtcctggtt
     9481 cataaatttc ccaaccccgg tgaggattga cttttttacc aggcatatca taaggttcaa
     9541 aataaatatc taagataagg aggtccccct cttgctgtga cttactaggt gcctgaaccc
     9601 gcaaaggctg ataataatta actcccaaaa aatcaacagt attgtttttg ataatctcta
     9661 attcatcagc actatattga ggtaataaat cagcttcctc taaaatggaa actaactctg
     9721 ctgggtaaac acccaaaact gatggatcta ggaaggattt ggtttggaaa agctctgcga
     9781 ttctagcagc cttgacatct tcaggagcat tactccgagg ataagcaggt gtcatgttaa
     9841 gcacaatact aatcttgtgg tcgggatgaa gcttatgaca agctttgacc gccagtgaac
     9901 tggccagttg tgtgttgtaa gccacttgaa ctgctgcctt ggcatctact ttacaagggt
     9961 agtgataata acctaaatag ccacattcga ctggaacaat cggttcatta aaggtaatcc
    10021 aagtgtttac taaatcacca aaaagctcaa aacaggtttt tgcgtaggtt tcataagccc
    10081 agacagtagc tttgttttcc cagccacctt tttcttgcaa ggcatagggg aggtcaaaat
    10141 gatagaggtt aacaatcaat ttaatacctt gagcaataat gtcttgaaat acttctcggt
    10201 aaaatgtcac cgcctttgga ttaacctccc cgactccttc tgaaatcaat cgagaccact
    10261 ggattgaggt ccgaaaaatc gtgtggcctg tttctttcaa aagggcaatg tcacccttat
    10321 agttttcata aaaggttgag gttttttctg gaccaatttg gtgatgaaac ttagctgact
    10381 caatactaaa ccagtaatcc cagttgctag gtcctttgcc atctccagga accgttcctt
    10441 cgctttgagg cccagatgtg gaacttcccc ataaaaagcc atctggaaat tgataacggt
    10501 gttttctttg tttcatatcc tttgtccttt ctttgctcac ttctcttttt attataagaa
    10561 gaaaaacagg tgatgtaaac gctttaaaaa atctgttttt tccttatcat cacggaaaat
    10621 aagtgattta aagcttgaca tattttatta tcttaaagag cctatctaac ctgccctgct
    10681 acttcttatc aaaaccaagc ccctattgac agatgcctta gcctatgttt gaataggggt
    10741 atggcttatt taaactactt tacaaaaacc gagtgggcac tttggttaag ctctgtcttg
    10801 gccattttaa ttagcgccct tttattcggt aagcaagctc ccttagcttt aatagcttct
    10861 ttgattggtg tgacctctct catttttagt gctaaagcta atcctattgg tcaagggctc
    10921 gtcattattt tttccattat ctatgcctat ctttcattac gaaacagtta ctatggagag
    10981 ttaatgacct atctttttat gaccctccct atgactattt tttcactttt tacttggtta
    11041 aaccatcctt ttgaagggaa aaaatcacaa gtgactattt cacgattaac acccactgat
    11101 cgaagatgtc ttttcgtttt tactatactg atcactctta ttttctacag catcttggct
    11161 tctattcaaa cagcctattt acttgtctcc actttatcga ttgccacttc tttctcagcg
    11221 gtttatctca gctataagcg cagcccttat tttgctttag catacgggct caatgatcta
    11281 gtcctcattc tcttatggat gcatgctgct caaacagatg ccagccaata tgctgtggtc
    11341 atctgctttg ccacctttct tattaatgat agttacactt tttataattg gctaatgctc
    11401 caacgttacc aagaaaaaaa ggtcaaaaaa ggatgagggc ctaagcctca tcctttttca
    11461 atttttcacg ttctaagcgc aaacgtctat tgggatttaa aagattaaac aattcttcta
    11521 atttctcagc attccaaaca tctgctgccg atacaaaatt tccatcctta tccttaaagg
    11581 atatcggttt atcacccata atcagaaacc tccatcttaa agataacaca caagagcact
    11641 atcacactgc tattgtaata gattgcctta atccacaaat tcaaattcaa acttgccaat
    11701 acgaacagga tccccatctt ttgctccacg ttcacgaaga gcttcgtcaa cccccatacc
    11761 gcgcaattga cgggcaaatt tcatgatgga ctcatcacgt tccatattgg tcatgacaaa
    11821 gagacgttct aacttctcac cagacaagac ccaagtagcg tcatcgtcac gtgtgatctc
    11881 aaagtctttt tcagtctcag caaagccata gtaagcttcc tcgtccacca gatcagattc
    11941 atcatataat aagaattcgt ctgttttagc gagtaattct gccgttgctt ctaacaagtt
    12001 ctctaagcct tgatgtgcta ggcttgaaat agggaaaatc attggcaaat catcaaactc
    12061 gtcatattgg gcagccaatt ttttcttgaa ggctttcaag ttttcttgag cctctggtat
    12121 gtccatttta ttagccacaa taatctgtgg gcgctccatc aatcgcaaat tataggtttc
    12181 cagctcgtta ttaatggaaa cataatcttc gtaaggatca cgaccctcac tagcagacat
    12241 gtcaatcaca tgaagaataa cccgtgtccg ctcgatatga cggaggaatt gagttcctaa
    12301 accaacccct tggctagcac cttcaatcaa acctggcaga tctgccatag caaagctatc
    12361 acctgacttt gtacgaacca ttccaagatt aggaacaata gtggtaaaat gataggcacc
    12421 aattttcggt ttagctgatg acacaacact taacaaggtt gatttcccaa cagatgggaa
    12481 tccgaccaag ccaacgtcag ctaagatttt gagttctaac tctaactgac gttcctcacc
    12541 tggctcacca ttttcagcaa tctctggcgc aggattacga ggagttgcaa aacgaatatt
    12601 cccacggcca ccacgaccac ccttagcaat gaccacttct tgaccatgtt ctactaagtc
    12661 tgtaattact tttccagttt cagcatcacg aaccgttgtc ccttgaggaa caaagacaat
    12721 caaatcttct gcaccacggc cgtgcatgcc tttggtcata cctttttcac cagatttcgc
    12781 cttgaattta cgattatacc ggaaatccat caaggtacgc aaaccttcgt ccactcggaa
    12841 gataactgag ccacctttac cgccgtctcc tccccaagga ccgccatttg ggacgtactt
    12901 ttcacgacga aaagctacca taccatcgcc accacggcct gcttggacac tgatttttgc
    12961 cgtatctaaa aacatactca tacttttttt attctctaac tttcttttac tttaaaaaaa
    13021 cgcctttcag cgtttcctta cattaatact gatagggcac tcgcaataag cccgccaaca
    13081 gttacaagaa ccattaggat aacaacaaac attgtcactt tttcaaaggt tgtttttttg
    13141 cgaggtccat tttctccaaa tgccacatta aatacctcat ctattgattt ttcttcttat
    13201 atcttaacat gaaagatcgt tttaggcaaa tatcagatga atatttacgc tatgtaggct
    13261 attactgagt attgtatctt gtgaatttca tatgaatatg atacattagc atttgcaaaa
    13321 taatgttaca gataaaaacc tcctcgtctg
//
LOCUS       DAUGQX010000048        12887 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUGQX010000048 DAUGQX010000000
VERSION     DAUGQX010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12887
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.048"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            166..693
                     /locus_tag="VIA51_001474"
     CDS             166..693
                     /locus_tag="VIA51_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEQ8683412.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            693..1811
                     /gene="yqeH"
                     /locus_tag="VIA51_001475"
     CDS             693..1811
                     /gene="yqeH"
                     /locus_tag="VIA51_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEQ8683413.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIGRINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLARFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPDKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            1836..2144
                     /gene="yhbY"
                     /locus_tag="VIA51_001476"
     CDS             1836..2144
                     /gene="yhbY"
                     /locus_tag="VIA51_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEQ8683414.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2213..2845
                     /locus_tag="VIA51_001477"
     CDS             2213..2845
                     /locus_tag="VIA51_001477"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEQ8683415.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLIDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            2842..3435
                     /gene="yqeK"
                     /locus_tag="VIA51_001478"
     CDS             2842..3435
                     /gene="yqeK"
                     /locus_tag="VIA51_001478"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEQ8683416.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3459..3812
                     /gene="rsfS"
                     /locus_tag="VIA51_001479"
     CDS             3459..3812
                     /gene="rsfS"
                     /locus_tag="VIA51_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEQ8683417.1"
                     /translation="MKKEELLKIVVEATEEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            3860..4603
                     /locus_tag="VIA51_001480"
     CDS             3860..4603
                     /locus_tag="VIA51_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8683418.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            4857..5963
                     /locus_tag="VIA51_001481"
     CDS             4857..5963
                     /locus_tag="VIA51_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEQ8683419.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENVID
                     YQKLIKVYEKKSEQMTAYLSTLEDTFSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6445..7161
                     /locus_tag="VIA51_001482"
     CDS             6445..7161
                     /locus_tag="VIA51_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8683420.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7364..8206
                     /locus_tag="VIA51_001483"
     CDS             7364..8206
                     /locus_tag="VIA51_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8683421.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8535..9380
                     /locus_tag="VIA51_001484"
     CDS             8535..9380
                     /locus_tag="VIA51_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8683422.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGTQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9630..10694
                     /locus_tag="VIA51_001485"
     CDS             9630..10694
                     /locus_tag="VIA51_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683423.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            10695..11387
                     /locus_tag="VIA51_001486"
     CDS             10695..11387
                     /locus_tag="VIA51_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683424.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11441..12811)
                     /gene="brnQ"
                     /locus_tag="VIA51_001487"
     CDS             complement(11441..12811)
                     /gene="brnQ"
                     /locus_tag="VIA51_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEQ8683425.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFVAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEMTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFIDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
BASE COUNT         4250 a         2035 c         2696 g         3906 t
ORIGIN      
        1 taagcagatg attgatttaa aaaggaatct tttcaaaatt gatgtccggg cacaaaagga
       61 tgaagagaaa gttttcatgc gtacggcgtg atttaactat ggttttaaat gctatttcaa
      121 aaaaaatatg ataaaataga aagtactaat tattttggag atgacatgag tatcgatgat
      181 tataggccga cctatatggt agaggctatt tatgatttaa gagcaaatga tttgttgcgt
      241 catggtatta cggctgtttt agtggattta gataatacct taattgcatg gaataatcct
      301 gatggcacac cagaggttcg cgcttggctt gatgaaatga ctatcgcgga tattagcgtg
      361 gttgttgttt caaataataa acattctcgt gttgagcgtg ccgtttcacg atttggtgtt
      421 gactttatta gccgtgcttt gaagccattt gcttatggta ttgaaaaagc cattgctcgt
      481 tatggatttg atcgcaacga ggttatcatg gttggagatc aactaatgac tgatatcaga
      541 gctagtcata gagctggaat aaaatcagtt ttagtcaaac cacttgttgc ttctgatgct
      601 tggaatacta aaattaaccg ctggcgtgaa cgccgtgtga tggcaaaatt agaagagaaa
      661 tatggtaaat tatcatatca aaaaggaatt taatggaaga attattttgt ataggctgtg
      721 gtatccagat tcaaactgaa gataaagaaa aagctggttt tacgccagct gctgctttga
      781 aaaagggtat ggaaacagga gaactctatt gtcagcgctg ctttagattg aggcattata
      841 atgaaattac agatgtccat attaccgatg atgaattttt aagacttctt cacgaagtgg
      901 gtgatagtga tgctcttgtg gttaatgtga ttgatatttt tgactttaat ggttctatta
      961 ttccaggtct atctcgcttt atttctggta atgatgtctt actggttggg aataaaaaag
     1021 atattttgcc aaagtctgtt aaggatggta aagttactca atggttgacg gaacgtgcac
     1081 acgaagaagg tcttcgccca ttagacgtta tgttaacgag cgctcaaaat aaatatgcga
     1141 ttaaagactt gattgggcgt atcaatgagt tacgtaatgg tcgagatgtt tatgttgtgg
     1201 gggtcactaa tgttggtaaa tcaaccttga ttaatgctat tatccaagag attactggta
     1261 acaaggatgt catcacgacg tctcgttttc ctgggacaac tcttgacaaa attgaaattc
     1321 ctttggatga tgggacgttc atttttgata cgccaggaat tattcacagg caccagatgg
     1381 ctcattattt atcccctaaa gagctaaaaa tagtgagtcc taagaaggaa atcaagccta
     1441 agacgtatca attaaatcca gaacaaactc tctttttagg tggtctggct cgctttgact
     1501 ttatcaacgg tgagcgtcaa ggatttacag ctttttttga caatcaacta gaattacatc
     1561 gtacaaaatt agctggagca gatgcttttt atgataagca tgttggaact ttgttaaccc
     1621 cgccagataa gaaagagttg actgcatttc ctaaattagt tcgtcatgaa tttacaattg
     1681 atcagaaaat ggatattgtt ttttctggtc taggatggat tcgtgttaat ggtcaaaaag
     1741 actcaaaagc gatagttgct gcatgggctc ctgaaggggt tgctgtcatt gttcgtaaag
     1801 cgattattta aaaataaaaa agaagttgga aaaaaatgct tacaagtaaa caaagagctt
     1861 tcttaaaatc tgaggctcat agcttaaaac cgattgtaca aattggcaaa aatggattaa
     1921 atgaccacat taagactagt attcgtcaag ctttggatgc tagagaattg ataaaggtca
     1981 ctttgttgca aaatactgat gaagatattc atgaagtagc agagatttta gaagaagaaa
     2041 ttgggtgtga tacggttttg aaaattggtc gtatcttgat tctctataag gtttctgcta
     2101 agaaagaaaa ccgcaagttg tcccctaaag ttaaagcaat ctagtccttt tatttgtata
     2161 gggactggtt ttatgagacg aggactattg tcgcgagaat tttggagaaa gtatggcatt
     2221 agaattgttg acgcctttta cgaaggtgga attagaggaa gaaaaaaaag aaagcaaccg
     2281 caaacagatt gggattttag gagggaattt taatcctatt cacaatgcac accttgtggt
     2341 tgcagatcaa gttcgccagc aattaggatt agatcaggtg ctattgatgc ctgaatgtaa
     2401 accaccgcat gtggatgcca aagagactat tgatgagaag catcgtcttc gcatgttgga
     2461 attggctatt gaagatgttg aagggctagc tattgaaacc tgtgaacttg aacgtcaggg
     2521 aatcagctat acctatgata cgatgcttta tttgactgag cagcatcctg atgttgattt
     2581 ttattttatc atcggagctg atatggttga ttatttgcca aagtggcacc gtattgatga
     2641 actggtcaaa ctcgttcaat ttgttggagt tcaacgtcca aaatataaag ctggaacctc
     2701 ttacccggtc atttgggtag atcttccttt gatagatatt tcttctagta tgattaggga
     2761 ttttattaaa aaaggtcgtc agcccaatta tctcttacct aagcgggttt tagactacat
     2821 tactcaagaa ggtttgtatc aatgacatat gaagattatc ttccttatag caggaccgaa
     2881 ctgttagcaa aaattgcaga gcagatgagc cctaaacggt ttaaacatgt acttggcgtg
     2941 gaaaaggcag ccttgtcctt ggcagagtgt tatggttgta acccagacaa agcagggtta
     3001 gcagctcttt tacatgatta tgccaaggag tgccctgacc aggtcttttt agacttaatt
     3061 gacaagtacc aattatctcc agaattagct aaatggaata ataatgtctg gcatggtatg
     3121 gttggtattt ataagattca agaagaccta gggctaaaag acaaagatat cttgcgagct
     3181 attgaaattc acaccgttgg tgctgctgag atgaccttgc tggataaggt cttatacgtt
     3241 gctgattata ttgaagaagg tcgcattttt cctttggttg atgacgctag aaaaatcgcg
     3301 aagctcgatt tgaatcaggc tgttgcctat gaaacagtga acactgtcgc ttatttagcc
     3361 tcaaaagcgc agcctatttt cccacaaact ctggatacct ataatgcgtt ttgcagctat
     3421 ttaaaggaat actaatggat aatgatatga ggaataaaat gaaaaaagaa gaactcttaa
     3481 aaattgttgt ggaagcaact gaggaaaagc gtgctaaaga tattttagcc ttggatttag
     3541 aggggttaac tagtttgacc gattattttg tgattgcgag tgcaacaaac agtcgtcaat
     3601 tagaggctat tgcggataat attcgtgaaa aggtaaaaga ggctggtgga gatgctagcc
     3661 atgttgaagg taatagccaa gcaggctggg tcttgcttga tttgaccgat gtggtggtac
     3721 atcttttttt agaagacgag cgttaccact ataatcttga aaaattgtgg catgaagcgc
     3781 ctgctgtggc tctagatgcc tatttagctt aatgttacaa agagaccttg tcaatacgac
     3841 agggtttttg aggatgataa tggaacataa ttatgaaaaa tttgcgtcag tttatgatgc
     3901 tgtgatggat gattctctat atgacttgtg gacagatttt tcacttcgac atttaccaaa
     3961 gtctaagggt cgaaatcgtt tgttagagtt ggcctgtgga accggtattc agtcagttcg
     4021 ttttgctcaa gcaggttttg atgtgactgg tttagactta agtcaagaca tgctggctat
     4081 tgctaaaaag cgtgcgcaat ctgctaaaaa gaaaattgat tttattcaag gtaacatgct
     4141 ggatttgtca caggtggggc agtttgattt tgtaacctgc tattcggatt ccatttgcta
     4201 tatgcaagac gaagttgatg ttggcgatgt ttttaaagaa gtttatgatg ttttagcaaa
     4261 cgatggcatc tttatttttg atgtgcattc aacctatcaa acggatgagt gtttccctgg
     4321 ttattcctat catgagaatg cagatgattt tgcaatggtt tgggatacct atgctgacga
     4381 ggctcctcac tctgttgttc acgaactcac tttctttatc caagaagacg atggacgttt
     4441 ttctcgcttt gatgaagtgc atgaggaacg aacgtatgag ttattgactt atgatatttt
     4501 gttggaacaa gcagggttca agtcatttaa ggtctatgct gattttgaag ataaggagcc
     4561 aactaagacc agcaagcgtt ggttttttgt agcatataaa tagaagaaaa aagtagcctt
     4621 tttagctata ggatttaatg aattatcttg aatgttactt atatgaaaag agttcattag
     4681 gcattaaatg ctattatcaa agcttagaag tattggagac attacgattg acactatgtc
     4741 tgaaggttgc taccaacttt aaagaaagca ttttctatta tacgttgtgc ttaagcattt
     4801 gatttaactc ttattagccc tataaaagac tatttagtac aatttgagga gattctatga
     4861 ctgttaccgg aattatagct gagtttaatc cgtttcacaa tggacacaaa tatttgctag
     4921 aaacagcaga gggactaaaa attattgcta tgtcaggaaa ttttatgcaa agaggagagc
     4981 ctgctcttat tgataaatgg attcgatcag agatggctct taaaaatggt gcagatattg
     5041 ttgtggaatt gccctttttc gtttcagttc aatcagcaga ctattttgct caaggagcta
     5101 ttgatattct ttgtcaatta ggaattcagc aattagcatt tgggacagag aatgtgattg
     5161 attatcaaaa actgattaag gtctatgaga aaaaatcaga gcaaatgact gcctatttat
     5221 cgacgcttga agatacattt agctatccac aaaaaacaca aaaaatgtgg gaaatctttg
     5281 ctggagttaa attttcaggg caaacgccaa atcatatttt ggggttaagt tacgcaaagg
     5341 ctagcgctgg aaagcatata caactatgtc ctatcaagcg tcaaggggct gcctaccatt
     5401 cgaaagacaa aaatcatctg ctagcttctg caagtgccat tagacagcac ctgaatgatt
     5461 gggatttcat aagtcattca gtaccaaatg caggtttact tataaacaat ccccatatgt
     5521 catgggacca ttatttttca ttcttaaaat atcaaattct gaaccattct gatttaacta
     5581 gtatttttca ggtcaatgat gaattggcaa gtcgtattaa aaaagcgata aaagttagtc
     5641 aaaatattga ccacctagtt gacactgttg ctaccaaacg ctatacaaaa gctcgtgtaa
     5701 gacgtatttt aacctacatt ttggttaatg ctaaggaacc tactttacct aaaggaattc
     5761 atattctagg gtttacctca aaaggacaag cacatttaaa aaaattaaaa aaaagcaggc
     5821 ctctgattac tagaattgga gcagaaactt gggatgagat gacacaaaaa gcagacagca
     5881 tctatcaact tgggcatcag gatatcccag aacaaagttt tggaagaata cctattataa
     5941 taaaaaatga gaggctcaat taaactctaa ttgagttttt ttgggggctt gactctaaca
     6001 ttacgttgat ggtttatact tcagttaatc caatgaggaa attttataac aataattaaa
     6061 aaagtcagtc aaaagatata ctttcgaaga acaggctaac gtttttacaa gattatatca
     6121 gtaatcattt tgacaattgt agtaatggaa tgttgccaaa atttagaacg ttgtatgtta
     6181 tggatgacaa gattttaaag gaatactaat taaacgggag gtcgtgaacc ggaagctgtt
     6241 gtcactcaag cgccaaaatc tgtctgtaac ataatattga tgtatgggaa cgcaattatt
     6301 tggtttttat tgtgatgctt aaaacgattt tatatttcta ttttaccaaa gcttttcaaa
     6361 gtgctataat aagggagtta gagtcaatat tagtaacgtt aatgttgaca atattcaata
     6421 aaatactatt aaaaggagac aaaaatggga cgtaaatggg caaatattgt tgctaaaaaa
     6481 actgctaaag atggagcaac atcaaaggtc tatgccaaat ttggtgttga aatttatgtg
     6541 gctgccaaac aaggcgagcc agatccagag ttaaatacag ctcttaaatt tgtcattgat
     6601 cgtgcaaagc aagcacaagt gccaaagcat gttattgata aagcgattga taaagctaaa
     6661 ggaaacacag atgaaacttt cgtagaggga cgctatgaag gttttggtcc aaatggttca
     6721 atgattattg tggatacttt gacatcaaat gttaaccgta cagcggcaaa tgtacgtacg
     6781 gcttacggta agaacggtgg caatatggga gcttcaggat ctgtatccta cttatttgat
     6841 aaaaaagggg tcatcgtttt tgctggtgat gatgctgaca gtgtctttga acaattactt
     6901 gaagcggatg tagacgtaga tgatgttgaa gcagaagagg gaacaataac agtttacact
     6961 gccccaacag atcttcataa aggtatccaa gcacttcgcg ataatggtgt agaagaattc
     7021 caagttactg aacttgaaat gattcctcaa tcagaagtag ttttggaagg tgatgacctt
     7081 gaaacttttg aaaagcttat tgatgcactt gaatcagatg atgatgttca aaaagtgtat
     7141 cataatgtag cagattttta aattgacata gaataataaa aagagttgaa atctatttca
     7201 gctcttttta agtgatgctt ttataagtaa gtaccaggta acatagtcgt tgttagaaga
     7261 taatgaacaa tagtaaatca gtatcaactt gataggaatc aattattagt gaactctaat
     7321 taaaaatggt aaactagaca caagaacaaa aaggagagat aggatgatta aaaaacagta
     7381 tttaggaagg gcaacaattg ccctagcatc gacccttgtg ctagcagctt gtgggtcatc
     7441 aaaaacagct gagtcaggaa atcaggggag ttctaaagaa gtcttatttg caacggttgg
     7501 aacaacagct cccttttctt atgaaaaagg tggtcaacta actggctacg atatcgaggt
     7561 ggctaaagca gtctttaaag gatcggatga ttacaaggtg tcctttaaaa aaacagaatg
     7621 gtcttctatc tttacaggtt tggactcagg aaaataccaa atgggtggta acaacatttc
     7681 ctttaccaaa gagcgttcag ctaagtacct tttttcttat ccaatcggat caacaccttc
     7741 tgttttagtt gttccaaaag acagtgatat caagagcttt gatgatatcc aagggcatac
     7801 gacacaagtt gttcaaggga ctacaagtgt tgcacagtta gaagacttta ataagaaaca
     7861 cagtgacaac ccggttactc taaaattcac caatgagaac attactcaaa tgttaaccaa
     7921 tttgagtgaa ggcaaggcag atttcaagat ttttgacgct ccaacggtta acgccattat
     7981 taaaaatcaa gggttagata atctcaaaac aattgaactc acctcaacag agcaaccatt
     8041 tatttatttt atctttagtc aagatcaaga gaaattgcaa agctttgtta acaagcgtat
     8101 taaagagttg actgctgatg gaactcttag caagcttgcc aaagagcacc ttggcggtga
     8161 ttacgtgcca tcagataaag agttgaaact tcctacagct aactaaacca tctattaacc
     8221 agttattcat ctagaagact ggtttttctg atcggaaaca atattatagt ttatgaggtt
     8281 atgttataaa aattgcaaat agccttaatc aaaatgagat gttaaagtgc tttttgagaa
     8341 gtgaatattg tataagaagt atgctttggg ttttagtcct caaataccaa gttttttgtt
     8401 gactaaacaa ataaggatgg ttagcatagc atatagttta aaactatggt atatgctagc
     8461 cattatcaat ttgaaaacta tatctaatta agatacaata atgatcgtaa acaaaatgaa
     8521 tcgaggataa cgctatgtct tttaaaaaat ggattggaat agtcggaatc gctttagcat
     8581 caactgtatt ggttgcttgt tctgaaaaac aagatgataa aaacacttta actattgggg
     8641 tgatgacaaa aacagaatct gatcaagcga gatgggataa agttgaagaa ttattgaaaa
     8701 aagacaatat cactttgaag tacaaagaat ttacagatta ctcgcaacct aataaggcag
     8761 ttgctaatgg tgaagtcgat attaatgcct tccaacacta taatttctta aataactgga
     8821 ataaggaaaa taaggaacat ttggtggcca ttgctgatac ctatatcagc ccaattaacc
     8881 ttttctctgg aaccagtcaa gatggaaagg ctaaatacaa atcagtagct gatctgccaa
     8941 atggtactca aattgcagta ccaaatgatg cgaccaatga aagccgtgcc ctctatgtgc
     9001 tgcaatcagc tggcctcatt aaattgaatg tgtctggtga tcaattagca accattgcca
     9061 atatctcaga gaacaaaaag aaattagata tcaaggaatt agatgctagc caaacggcac
     9121 gtgctttagt atctgctgat gcagctgttg tcaataatag ttacgctgtt cctgcaaaaa
     9181 ttgactacaa aacctctctt ttcaaagaaa aagcagatga caattcaaaa cagtggatta
     9241 acattattgc aggtcaaaaa gattgggaaa aatcagagaa ggctgatgct attaaaaaac
     9301 tcatcaaggc ctaccaaact gatgaggtga agaaagtcgt ggaaaaaact tcaaatggta
     9361 tagatgtatc cgtatggtaa attttagcca ttgttataac aagagtgtgg tcgtgtttaa
     9421 aacacatgct ttcttgcatg cttgaggaag agtttacgac taatttacct ttagaaagct
     9481 atttaagacc ttttcccttt taggatttag aaaccttggg aagactattg catgttatct
     9541 taatagtcat gattatgcag gcgatgaaaa cattgctatc gtagattact gtcgccatat
     9601 cgtactaata gaggagttat taaaatctta tgaatgaagc aataattcaa ttagatcata
     9661 ttgatattac cttccgtcaa aaaaaacggg ttatcgaagc tgttaaagat gtcacggttc
     9721 atatcaatca aggagatatt tatggcattg ttgggtattc aggtgccggg aaatcaactc
     9781 ttgtgcgtgt gattaacctg ctacaggcac caacaaacgg gaaaatcact gttgatgggg
     9841 atgtgacttt tgaccagggg aaaattcaat tgtcagctga tgcccttcgc caaaaacgac
     9901 gtgatattgg tatgatcttc caacatttca atttgatggc ccaaaaaaca gccaaagaaa
     9961 atgtagcatt tgcgctccgt cattcgtcgt taagtaagac tgagaaagaa cacaaagtta
    10021 tcgaactgct agaacttgta ggtttatcag agcgagcaga taactaccct gcccagttat
    10081 cgggtgggca aaaacaaagg gtggctattg cgcgtgctct agctaacgat ccaaaaattt
    10141 tgatttcaga tgaggccaca tcagcactag atccaaaaac cactaaacaa attttggcgc
    10201 tcttgcaaga attaaaccgc aaacttggcc ttaccattgt tatgattact catgaaatgc
    10261 aaattgttaa ggatatttgt aatcgtgttg ctgttatgca aaatggtgtt ttgattgaag
    10321 aaggttctgt ccttgatatc ttttcaaatc caaaagaagc cttgacacag gaatttatca
    10381 caacagctac agggattgat gaggctttag aaaaaattaa ccaacaagac attgttaaac
    10441 atttgcctgc aaatgccctt ctagctcagt tgaaatatgc aggaacttct acggatgagc
    10501 ctctacttaa tagcatttac cgtcagtttg aagtgacagc taatattttg tatggcaata
    10561 ttgagatttt agatcatatt ccagttggtg acatgattgt tgtcttggaa gggcaagctg
    10621 aaaatattct tgcggctgag aaagccttgc atgaagctgg tgttgatgtt agtattttaa
    10681 agagaggagc ctagatgtca cagttaattc aaacttattt gccaaatgtt tatgaactcg
    10741 gatggtctgg agatgctggt tggggcttag cgatttggaa tactttatac atgaccattg
    10801 tgccttttat tgttgggggt gctattggtc tcttattagg cttgttatta gttttaacag
    10861 gaccggacgg tgttattgaa aacaaaacga tttgttgggt tattgataaa gttacctcta
    10921 tttttagagc cattcctttt gttattttga ttgctatttt agctagcttt acctatttgc
    10981 ttttaagaac aactttagga gcaacagcgg ccttggtacc tttaaccttt gcgacttttc
    11041 ctttttatgc ccgtcaggtc caagttgttt tttcagaatt agacaagggt gttattgaag
    11101 cagcacaagc ttcaggtgct actttctggg atattgtcaa agtgtatctc agtgaaggtt
    11161 taccagatct tattcgtgtt tctacagtca ccttaatttc tttagttggg gaaactgcca
    11221 tggcaggagc tatcggtgct ggaggattag gaaatgtagc gatttcttat ggttataatc
    11281 gttttaacaa tgatgtgact tgggtagcga ctattattat tcttttaatt atttttgcta
    11341 tccaatttat tggtgatagc ttgactagaa ggtttagtca taaataaacg aaacaacacc
    11401 ctaagtaaaa acttagggtg ttgttgttta gatgatgtca ttagcttttc ttcgttttac
    11461 ttagtataag ccctattaaa aaaccaatag cagcaaagat aatccatccc attgagaatt
    11521 gccctagtgg aacagttttt tggaaaaaag ttacaacggc ttctggtaaa tgaaataatc
    11581 cagtcatttg tgatagtgtt aggagtgcat caaatatggc aggaataaag gttagaccaa
    11641 ttgtagttcg atagacaata ggatcattat tgaagcattt ttgtgccaaa acaaggaaaa
    11701 ttaaatcgac tgttaatggg tataaaagga ataaaacagg agctgaccag ttgataatga
    11761 ctgataagcc accaaaataa aagaaagctg atagtaaagt aaagatagtt gcccaagcaa
    11821 tatgagataa agcaggcact aatttatgga agtattcagc acttgacgtg attaagcctg
    11881 ttgaagtggt tagacaggcc aggaaaatca caacagctag aaatgcttgt ccgatgccac
    11941 ctaggtaaaa acgagaagca tgacttaaga tttgaccgcc attaactgga ttaccatgaa
    12001 gggtaaagct gccatcaata aaaggaaata atgattgtga tgttgctcca atacgaccga
    12061 caaagatata gacaagtgct aatagcaaaa tggcaatagc cccagaaata agtgttattt
    12121 tggtcatttc tttgtccgtc ttagcgccaa attgtttggt agcctcaatg actaaaatag
    12181 caaaaacaag agaagctagt gcatccatag tgccataacc ttgaattaat cctgctacaa
    12241 aaggaaaatc tttaaaggca ttattaacac cgaccccagc gttaaaagca tcaccgtaat
    12301 ttccagcagg atggacaaag gacgcgataa ccaaaataga aataacaact aacaacgttg
    12361 gcgttaaaaa ttttccgata ttttcagcta gtttactagg tttgatagca aggaagtagg
    12421 acagaccaaa aaatagtata gcataaatag ctttattggt tgtattatct cctaagatag
    12481 gagcgatacc gactgaaaaa gaagtggctc ctgttcttgg aatagcaaaa aatgggccaa
    12541 tagataaata caaaatggaa gaatagaaga ttgcatacca tttagagatg gggcgtgcca
    12601 aactttcaac atcgcctgat ccagatttag caacagcaat gacaccgagt aaaggcaagg
    12661 agacaccagt taaacaaaaa ccaatgatag accatagaat ctgatgacct gagtagatgc
    12721 ctaaaaaagc tgggtaaatg aggtttgctg ctccaaaaaa tagcgcaaat agcatgaatc
    12781 caatgacgat atatacattt ttttgtttca tttataaata gtctttctat tgatactaat
    12841 ccgaagattc taacaatttt aattatatta tgtgtcaaaa taacaac
//
LOCUS       DAUGQX010000049        10158 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUGQX010000049 DAUGQX010000000
VERSION     DAUGQX010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10158
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.049"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(264..1406)
                     /locus_tag="VIA51_001488"
     CDS             complement(264..1406)
                     /locus_tag="VIA51_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEQ8683426.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLVALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITSNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFCQTTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
     gene            1688..4666
                     /locus_tag="VIA51_001489"
     CDS             1688..4666
                     /locus_tag="VIA51_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEQ8683427.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRYLTNTFRNSRWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLDSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLMKKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIVYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            4679..5878
                     /locus_tag="VIA51_001490"
     CDS             4679..5878
                     /locus_tag="VIA51_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8683428.1"
                     /translation="MTKSKQPQYRFDGFEGEWEEKELGDIVQITMGQSPSSQNYTTNP
                     SDYILVQGNADIKNGYVFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIGRG
                     VAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIPSLPEQEAIGE
                     LFQMVDQLIQLQDQKLATLKEQKQTFLRKMFPAQGQKVPEIRLQGFKGEWEEKKLREV
                     STHRSGTAIEKYFDSEGEFKVISIGSYGTNNLYVDQNIRAVSNELTNSKLVASGELTM
                     VLNDKTANGAIIGRCLLITENNKYVVNQRTEIIRPDINISSYYLFHYLNGEFRNGIIK
                     IAQGGTQIYVNYSSVEQLKINIPTLKEQEAIGNFFQTLDQQIAQSEEKLTELKALKQT
                     LLNRLFV"
     gene            5891..7471
                     /locus_tag="VIA51_001491"
     CDS             5891..7471
                     /locus_tag="VIA51_001491"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEQ8683429.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLLAVCDNLEKHFNTFTEAQKIFEDAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPINFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDNHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(8024..8629)
                     /locus_tag="VIA51_001492"
     CDS             complement(8024..8629)
                     /locus_tag="VIA51_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8683430.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLANISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(8610..10031)
                     /locus_tag="VIA51_001493"
     CDS             complement(8610..10031)
                     /locus_tag="VIA51_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683431.1"
                     /translation="MTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTR
                     GTPLFLSSGLQIILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNRIL
                     FNFLFLMVFTILHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEML
                     DVNQAFNNLGWYLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWI
                     VLMKVLVKDFLLFFIVVDASTLFCLVVISCIFYYLENSKQNFDYENRRLNYFMKSEEN
                     MRVEFSNYLHDDVLQNIIAIKNLFSLENSNITHGFIVNELNDLVSGIRDEMDTYHPIV
                     PANQTMKENIQSLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIK
                     YGDGKDIRLSLTIQSDIIIIEESNQVVEKVHSINYGRGLKSFQETLAAFDGDLELQMD
                     TKQFTIRILLPIDWKLCYEDFIN"
BASE COUNT         3468 a         1903 c         1693 g         3094 t
ORIGIN      
        1 acgtctccta agagacaact tctttattct atcaggtttc tcatagcctg tcaactactt
       61 tttcatcttt tttcaataag tgtgttacag gaacctctct gacagcttta ttagtatacg
      121 atatctttac tgtcattgtc aactcttttt tacaaaatgt ttctgttttt catactatgc
      181 taatgagtta gctcgtgcgt ctccttcttc ataggttact tttaaccacc aaatgaatgc
      241 tacacaatcg aaaatagatg agtttactta ttaaactgag ctatcaatag cataaggtta
      301 gctgctaata ttttgatatt agaaagtgtt gttgttttat ctatcgctgc ttctaaggaa
      361 attggctgct gttgtattga aaaaacagcc aaaaagtctt ctgctgctag tcctgtctca
      421 atctttacag aaccacatag agcaatcgtt ggaacttgat attttttagc cattcttgca
      481 atcgcaacag gtaccttgcc agattgtgat tgtgtatcca ggcatccttc tccagtaata
      541 actaaatcac aagactgaag ggaattatcc agatttagta gctctgcaat cctgctaaaa
      601 ccactagtta aggtgcctcc taataggaca atggcacctc ctaatcctcc agctgctcca
      661 cttcctggta ttgtctgtaa atcaatggtt gtttggcaaa aaactttttt agcaaagtta
      721 cttgcaattt gatcagtttc ttcaatttga ctaagactcc cacctttttg agggccaaag
      781 accgcagcaa atccttgagg gccatgatat ggattggtca catcagtcag ccctaatagc
      841 gtaacaggtg atgctaaagt atcaagataa gatcttcctg tcatgaaatc atagtttaaa
      901 ctttccaaaa accctttgcc accatcagaa gtgcctgtgc ctcctagcat gatttcgatt
      961 tgagtagctc ctttttgaat ggcatcttta actgccaaac ccaaaccgta ggaagtggct
     1021 tgtgcatagg ttactgaatt ggaggtgatc ttatcaatac caataatact cgcagattca
     1081 ataaaagctt gctttgcgtg acgataataa gcgactttaa tcgggcgtct taatagatca
     1141 atggttttta cttgatgcca cctccccgcc acggtttgtg agagggctac taaacttcct
     1201 tctcctccat cagcgatagc tcttgtttca ataactaact gcttatcgac agaaagaagg
     1261 gcttgagcta cactagtgtt aagttctgga gacgttaccg atcccttaaa agaatctatg
     1321 gctaccaaaa ttttcatatc ttcaataaat tccttttctg tatattgtag cagattatca
     1381 tcctttaaaa ccctattaat agtcaagcta gatctgtctt aagtttttta tctattttga
     1441 gaactcgacc tttttactag tgttgtctta ttactttctt caccttaaat tattgtcaag
     1501 caaactcaaa aatacaagaa ctttctcgat tgcatttaca tagtcatagc tttgtttagc
     1561 tgctaggatc ttaagcattc aactaatcaa aaaaaagact gtttggaagg tttcaatagc
     1621 ttcgccattc taaaaaggat ccgccaatga tataatatta ctatatcatg tcgaatgggg
     1681 attaaaaatg ggaaatcaaa ctaaaacgga acttgaactt gaaaaagagt tgatccatct
     1741 cttagaaaca ggtgaaagtc aatggacata tcgtaaagaa ttaaaaactg aagatgcttt
     1801 atgggataat ttctttaaga tcttagcgca aaataacacg caatatctga acgaggagcc
     1861 tttaacagct agtgaaaaag agcagattaa gaatcaactt aactttgtca attactatga
     1921 agcggctaaa tggttagctg gtgaaaacgg cattgctaaa gtacaagtgc aacgcgaaga
     1981 tgcaaaacta ggaacgattc gtttagaagt cgttaaagca gacaatgtgg ctggtggaac
     2041 ttctgtttat gagattgcca atcaagttgc tttctctggt tctcgtgata gacgaggtga
     2101 tgtgacactt ctcatcaatg gcttacctat gatccaaatt gaattaaaat ctcagaatca
     2161 tcaatgcatt gaagctttta accaagtcaa aaagtatgat aaagaaggcc agtttagagg
     2221 tatcttttca accttacaaa tgtttgtggt ctcaaataaa acagatacaa ggtatatcgc
     2281 tgcagctaaa gaaaataaat taaaccctaa cttcttgacc caatgggtag atcaaaacaa
     2341 caaaccacaa aaagatctct ttgcctttgc caaagaagtc ctatctatcc ctcgtgctca
     2401 ccaaatggtc atgacttact ctgtcattga tgatgataaa aaagcactaa ttctccttcg
     2461 tccttatcag attcatgcaa tcgaagccgt cgctgaagcg agtcgtcacc gcaagtctgg
     2521 ctatatctgg cacacaacag gttctggaaa aaccttaact tcctataaag tggctcgcaa
     2581 tatccttcaa ataccggccg ttgaaaaatc catctttgtc attgaccgaa aggatttaga
     2641 taatcagacc gcttctgctt ttcaatccta tgcgcaaaat gatatctttg atgtcgatga
     2701 gacagaagat acgagacaac tcatcaaaaa tttagaatcc agcgatcgtc gtgttgtggt
     2761 caccaccatt caaaaactca atgccatgat cagtcagatg gaaagttatg acactccaaa
     2821 attcaagaaa ctaaaagagc gtcttgcaca cttaaatgtt gtctttgttg tggacgaatg
     2881 ccaccgtgct gtcacgccag aacgtcaacg ttatctcacg aatacttttc gtaacagtcg
     2941 ctggtatggc tttaccggca ctcctatctt tgtggaaaat aagcgtgctc aattaggtga
     3001 tttagcccaa acaacggaac agcaatacgg caaatgtctc catcaataca ccgttaaaga
     3061 agccattcat gataaagcgg ttctaggctt tcaagttgag tataagacaa ccattcctga
     3121 tatgcctgaa gacagtattc cggaagaagc ttatgatcat gaagaacata tgttagctgt
     3181 cttagatagt atcattaatc aatcacgcaa gaaacttggt tttaataatg gaattggtca
     3241 gacattcgaa ggtttactaa ccgttaagag tattgctcgt gcccaagcct attatgatct
     3301 gatgaagaaa gttaaggctg gtgaaacgga tttagtcatt tctaagaagg tcaaagaaaa
     3361 actaccagac tttccaaagg tagctattac ttattctatc actgaaaatg acaatgcgtc
     3421 tatcagccga caagataaaa tgaccaaaaa tctagaagac tataatcacc tctttggcac
     3481 taactttacc atcgataact tacaaggcta taacagagat ttaaatgatc gcttagcccg
     3541 taaaaaagat aaattcaaag accgtcatga acaattagac ctcgtgattg tggttgaccg
     3601 tctcttaaca ggttttgatg cgccttgttt atcaacgatc tttattgatc gccagcctat
     3661 gaaacctcag cacattattc aagctttctc acgaaccaac cgtatctttg aaagtagaaa
     3721 acattacggt caggttgtga ctttccaaac accacttcgt tttaaagaag ctgtcgacaa
     3781 agcgcttagc ctctactcta atgggggtga aaacgacgtt ttggcccctt cttgggaaga
     3841 agaaaaagca agattctttg aaaaagtaac agtattaaaa aatatagttc ctgatccaga
     3901 cgctttccca actattgaga gcgcacagac agcttttctc aaacaatacg ccaaagcctt
     3961 tcaagcgttt gataaactct ttgcatctgt acaggtctat agtgatttta atgaaacact
     4021 gttgagtgag gttgggttat cagatgaagt gattgatact tataaaggca cttaccaaaa
     4081 tgtcattgca gaaatacgaa agcgaagaga agatgacgaa gccatcccag agatcaatat
     4141 cgactatgag ctagaaagtg ttcagatgga tgatatcaac tatcactata tcttgacctt
     4201 aattcaagcc tttgtcgatc aagaacaaga agctcttcaa gaaaggctca atgacaatcc
     4261 tatggatcaa tacatccaag atttggcaaa atcaaaccct gctatggctg actcactagc
     4321 tgagttatgg caagatatcc aaaaagaacc caaagcctat gaagggaaaa gcattgttta
     4381 tgagttagat aacctcattg gtgataagat ccaaagggcc atcaaacact ttgcggacca
     4441 atggaaggca gatcctgaca aattagcctt tgtggcgact aattatcata gtgctaactc
     4501 taccaaacaa gtgggcatgt caaccttaaa agaatcccta gactaccaag cctataaaga
     4561 aaaacaaggt gattctgcca tgaataaact caaatacaag agccaatttg aacgggagtt
     4621 agttcaattc attagagatc aaatccaacc cttaaaaggg cactaggaaa ggaaagagat
     4681 gacaaaatct aaacagcctc aatatcgctt tgacggtttt gaaggggagt gggaagaaaa
     4741 agaactaggg gatattgttc aaattacaat gggccaatct ccatcaagtc aaaattatac
     4801 tacaaaccct tctgattata ttctagtaca aggaaatgcc gatataaaaa atggatatgt
     4861 ttttccgcgt gtctggacaa cacaaattac aaaacaagct gacaaaggtg atattattct
     4921 tagtgttagg gctccagttg gtgatgttgg aaagacaaat tatcatgtta ttattgggcg
     4981 tggagttgct gctataaaag gtaatgaatt tatctttcaa atattaaaat acttgaaaga
     5041 aattggttat tggaaaagaa ttagtacagg ttcaactttt gatagcatta gctctagtga
     5101 tatcaaatat gctaaaattc aaattccctc cctccctgaa caagaagcca ttggcgaact
     5161 tttccaaatg gttgatcaat tgattcagtt gcaggatcaa aagctagcaa cccttaaaga
     5221 acaaaagcaa accttcctca ggaaaatgtt cccagctcaa ggacaaaaag tccctgaaat
     5281 ccgtttacaa ggttttaaag gagagtggga agagaagaaa ttgagggaag tatctactca
     5341 tagaagtgga acggcaattg aaaaatattt tgattcggaa ggtgaattta aagtcatttc
     5401 aataggtagt tatggaacta ataacctcta tgtagaccaa aatattagag cagtctcaaa
     5461 tgaacttact aattctaaat tagttgcctc cggtgaatta acaatggtac tcaatgataa
     5521 gacagcgaat ggggcaataa tcggaagatg tctacttatt acagaaaata ataaatacgt
     5581 tgttaatcaa agaacagaaa ttattagacc agatattaat atttcctctt actatctttt
     5641 ccattattta aatggcgaat ttcgtaatgg tatcattaaa attgctcaag gtggcactca
     5701 aatctatgta aattattcat ctgttgaaca attaaagata aatataccta cattaaaaga
     5761 acaagaagcc attggtaatt tcttccaaac tttagaccaa caaattgctc aatctgaaga
     5821 aaaactaaca gaactcaaag cactcaaaca aacattactc aatcgtttat tcgtataaga
     5881 aaggactcac atggcagaga aaacaacttc actccgtcaa gcactatggc attcggccga
     5941 ccaattacgt ggccaaatgg atgccaatga ctataaaaac tatcttcttg gacttatttt
     6001 ttacaaacac ttatctgata aattactctt ggctgtttgt gataatctag aaaaacactt
     6061 caataccttt acagaggctc aaaaaatctt tgaagatgct tatcaagatg aaggcctaaa
     6121 agatgacctc atttctgttg ttactggtga tttaggttac tttatcgaac cgacactgac
     6181 ctttgaaaaa ctcatccaag atgtttatca caatactttc caattagaat cattagctca
     6241 aggttttcgc gatattgaac aaagtggtga agactttgaa aacttatttg aagatattga
     6301 cctctactct aaaaaattag gctctactcc tcaaaaacaa aatcaaacca tttctaatgt
     6361 catgaaaaca ttaaatgaaa ttgactttga ggcagtagat ggggatactt taggtgatgc
     6421 ttatgagtac ttgattggtg aatttgccag tgaatcagga aaaaaagcag gtgagttcta
     6481 taccccacaa gctgtctctc acttaatgac tcagattgtc tttttaggtc gtgaagatca
     6541 aaaaggaatg accctctatg accctgctat gggatctgga tcactccttt taaatgctaa
     6601 gaaatatagt aaccaatccg ataccgtttc ttactatggt caagaaatca atacttctac
     6661 ttataacttg gctcgtatga acatgatgct tcatggcgtt gccatcgaga accaacactt
     6721 aagtaacgct gataccttgg atgcagactg gccaacagat gaaccaatca actttgatgg
     6781 ggtgttgatg aacccacctt attctttgaa atggtcagcg actgctggtt tcttaacgga
     6841 tccacggttt tcaagttatg gtgtattagc accaaaatca aaagccgatt ttgccttttt
     6901 acttcatggt ttctatcatt taaaaaatac aggaactatg gcgattgtct taccacacgg
     6961 tgtccttttc cgtggagctg cagaaggcaa gattcgccaa aaactactcg aacaaggggc
     7021 tatcgatacc attatcggac tcccatcaaa tatcttttat aatacaagca tccctacgac
     7081 tattatcata ttaaagaaga acagaaccaa caaagatgtc ttctttatcg atgcttcaaa
     7141 agagtttgat aagggtaaaa atcaaaacac aatgacagat aaccatatca aaaagatcct
     7201 tgatgcttat aagagtcgtg ataattctga taagttttca tatttagcct catttgatga
     7261 aatcattgaa aatgactata acttaaatat cccacgctat gttgatacct ttgaggaagt
     7321 cccagttaaa ccactgccag aattagctaa acagctcagt gacattgatc aagaaattgc
     7381 caaaacaaat gccaaactag atcaactcat gaaacaacta gtcggaacaa ccaaagaagc
     7441 acaagacgaa ttggatactt ttagaaacta aaagacaaaa aaacaccaca gtagatgatt
     7501 actactgtgg cgttttattt aaaattgagt agtgaacctt tattgagtac ttatcaaaca
     7561 agattctcct tcttcaccta taaatcaaaa tagaatcatc tcatctaact ttgtccgttt
     7621 ctttgtttta tttaaaatag ttatttgaag ttacaatgat ttctcaaacg tttagaaatc
     7681 ttaaacacgg ttaagagaaa ttttcaggac aacttttgat ccttccacaa aaaccatggt
     7741 gcgaaccata aagtagttcc aatcgttgat atataagcat atattaacgt tctgggagtt
     7801 gtgaagcttt acaagttttt ttagacctgg tttaaacaac ttttgtttga ctaaatttaa
     7861 aaagcttttc atatcaggca tttccctact ttttataaaa gcgttatctc aatcaatttc
     7921 aatcaaaaag aactaaaaaa acaatgagtt taaatctggg tatttaacag gaaatcccta
     7981 gcaacgacac aagtaaaact tatgtcgttt gattatctgc aactcagaaa tccataaaat
     8041 accctaattg ttcggctttg tagatagcct cctgcttatt atttaccaaa agctttgagt
     8101 agatgtgggt caaatgatta aatactgttc tcctactaat ttgtaacgtt tcctctattt
     8161 cttttataga gaatcctttc ttactcaaat ttaagatagc tatttcctgg tcagttaaag
     8221 attcaacata atcctgagat tcgatttgtt caaaatactt ttttccagaa tccacttttt
     8281 ttaagataga aatgagttgt ttagggtcta tatttttatc tacaaaaccg tatgctccta
     8341 ctttttttgc cctctctcta tagattgatt taacatatcc tgtcaacata acaactttca
     8401 aatgaggagt agactgtatg agttcttttg ctatctccaa tccattttct ttagaaatat
     8461 ttgctaaatt aatatcaagc aatataatat cgtacttaga caaatcaatc gtcacatcgt
     8521 taaaatgaga agtaatcgta tctatgacat ctacttcatc atactgttgg aataacagtt
     8581 ggatactctt tgcaaatagt ctgtggtcat caattaataa aatcttcata acacaatttc
     8641 caatctatgg gaagtaatat tctgatagta aattgtttag tatccatttg tagttctaga
     8701 tctccatcaa aagctgctag tgtttcttga aatgatttca atcctctgcc ataatttata
     8761 gagtgtactt tttccactac ttgattgctc tcctcaatga taataatatc agattgaatc
     8821 gttaaagata aacgaatgtc ttttccatct ccatatttta tagcattgtt tattagctct
     8881 tttataaacc tataaacaat atctccatat ggggatggca ctaccatatt atctgaacag
     8941 ttaaaataca ataaggtatt actttttcta cttttaacaa tatcatcaaa aagagactgt
     9001 atgttttctt tcattgtttg attagcggga actattgggt ggtaagtatc catttcatct
     9061 ctgataccag aaactaaatc attcaactca ttaacaataa aaccatgtgt tatattacta
     9121 ttttctagag aaaacaagtt ttttatcgct atgatatttt gtaaaacatc atcatgcaaa
     9181 taatttgaga actccactct catgttttcc tctgatttca taaaatagtt cagtcttcta
     9241 ttttcatagt caaaattttg tttggagttt tctaaataat aaaagatgca agaaattacc
     9301 actagacaaa acaacgtgct tgcgtcaaca actataaaaa atagcaaaaa atctttaact
     9361 aataccttca tgagtacaat ccaacaaagg ataagaagta gaaataatag ttctatacga
     9421 gctttgtaat cacctaacca tctttgggta acaaaactca atttatcatg tatggtctta
     9481 aaatagtata ttacactcat tataagggga aacagatacc atcccaaatt attaaaggct
     9541 tgattaacat ctagcatttc tccataaagt tcactaccaa gtattaccag caaaagtaaa
     9601 gaaaatagta tcaatgaacg tctaacaact gatatttgtt gcctaaagga cctataatat
     9661 agcactataa ctagtaacgg atacaggtgt aaaatagtaa aaaccatcag gaataaaaaa
     9721 ttaaataaaa ttctattaac aaaaaggcta gttatagaaa caaaaataat tattaacaag
     9781 cccttatcta acttatcttt aaattgtttg tgcccatata atattaaatt agtaatctca
     9841 acggtataac aatagagcaa tataatctgt agtccactgc ttaaaaagag aggagttcct
     9901 cttgtcagca cagatactaa gtattgccaa attgttaagg agatgataga aataatcctt
     9961 ttaaaaatat caccttgttt ttggcgtaat attgttgcca gccaaataaa agctgtatca
    10021 ataagggtca ttacaagagc tactttttca gagaaaagaa gagacaggtt ctctcgatta
    10081 tagaccaaaa ttaacaaggc tattaattgt tgcaacaaga ttattgcagt cccaaagaac
    10141 ttactctttg ttatgttt
//
LOCUS       DAUGQX010000050         9763 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUGQX010000050 DAUGQX010000000
VERSION     DAUGQX010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9763
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.050"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..844
                     /gene="dnaN"
                     /locus_tag="VIA51_001494"
     CDS             <1..844
                     /gene="dnaN"
                     /locus_tag="VIA51_001494"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ8683432.1"
                     /translation="IEQHQVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLL
                     KSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFD
                     VVIPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMT
                     EFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLD
                     IVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITP
                     VRTN"
     gene            919..1116
                     /locus_tag="VIA51_001495"
     CDS             919..1116
                     /locus_tag="VIA51_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEQ8683433.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            1446..2561
                     /gene="ychF"
                     /locus_tag="VIA51_001496"
     CDS             1446..2561
                     /gene="ychF"
                     /locus_tag="VIA51_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEQ8683434.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREIDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            2631..3200
                     /locus_tag="VIA51_001497"
     CDS             2631..3200
                     /locus_tag="VIA51_001497"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEQ8683435.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            3203..6706
                     /gene="mfd"
                     /locus_tag="VIA51_001498"
     CDS             3203..6706
                     /gene="mfd"
                     /locus_tag="VIA51_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEQ8683436.1"
                     /translation="MDILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKTLAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSGLRILLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GIFINPASDLIFEVSDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFTDNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQISSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYIADERQK
                     IDIYKRIREIQSREDYLNLQDELMDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            6868..7140
                     /locus_tag="VIA51_001499"
     CDS             6868..7140
                     /locus_tag="VIA51_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEQ8683437.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            7127..7498
                     /locus_tag="VIA51_001500"
     CDS             7127..7498
                     /locus_tag="VIA51_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEQ8683438.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKSTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            7633..8919
                     /locus_tag="VIA51_001501"
     CDS             7633..8919
                     /locus_tag="VIA51_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEQ8683439.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQIPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFLFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            8916..>9763
                     /gene="tilS"
                     /locus_tag="VIA51_001502"
     CDS             8916..>9763
                     /gene="tilS"
                     /locus_tag="VIA51_001502"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8683440.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTA
                     KQGYYYL"
BASE COUNT         3453 a         1452 c         1793 g         3065 t
ORIGIN      
        1 aattgaacaa caccaagttg ttttaaccag tggtaaatca gagattacct taaaaggaaa
       61 agatgttgac cagtatcctc gtctacaaga agtatcaaca gaaaatcctt tgattttaaa
      121 aacaaaatta ttgaagtcta ttattgctga aacagctttt gcagccagtt tacaagaaag
      181 tcgtcctatt ttaacaggag ttcatattgt attaagtaat cataaagatt ttaaagcagt
      241 agcgactgac tctcatcgta tgagccaacg tttaatcact ttggacaata cttcagcaga
      301 ttttgatgta gttattccaa gtaaatcttt gagagaattt tcagcagtat ttacagatga
      361 tattgagacc gttgaggtat ttttctcacc aagccaaatc ttgttcagaa gtgaacacat
      421 ttctttttat acacgcctct tagaaggaaa ttatcccgat acagaccgtt tattaatgac
      481 agaatttgag acggaggttg ttttcaatac ccaatccctt cgccacgcta tggaacgtgc
      541 cttcttgatt tctaatgcta ctcaaaatgg tactgttaag cttgagatta ctcaaaatca
      601 tatttcagct catgttaact cacctgaggt tggtaaggta aacgaggatt tagatattgt
      661 tagtcagtct ggtagtgatt taactatcag cttcaatcca acttacctta ttgagtcttt
      721 aaaagctatt aaaagtgaaa cagtaaaaat tcatttctta tcaccagttc gaccattcac
      781 cctaacacca ggcgatgagg aagaaagttt tatccaatta attacaccag tacgaacaaa
      841 ctaagtaaga aaaagctccc ttttaggagt ttttttgtta ttataaatat taacgataat
      901 ataagtggag aaaagggaat gtatcaaatt ggatcatttg ttgaaatgaa aaaacctcat
      961 gcttgtgtaa ttaaagaaac tggtaaaaag gctaatcaat ggaaggtact gagagtagga
     1021 gctgatatta aaattcagtg tactaactgt cagcatgtga ttatgatgag tcgttatgat
     1081 tttgagcgaa aattaaaaaa agtactgcaa ccatgaaagt ccttttaaat aaataattct
     1141 agctatattt gcaaccaata ctttgctaaa aaattgctag tatgccgttg gaaaattagc
     1201 tattctaatg ttatcgaaag aagaaagatg gccattgaca atgacgaaag ttgtagcaca
     1261 gttacttagt ttctcggcaa actatatcaa aatgagaata atacaccaaa ctttgataat
     1321 ttaaatgaag gtgaaagagt ggcataatga taagcaaatc tgaaattttc ttcttattca
     1381 taccgctttt tcttctattt tttggtataa taatcttgat tgaaatttga atggagattc
     1441 gctaaatggc tttaacagca ggtattgtag gcttaccaaa tgttggtaaa tcaaccttat
     1501 ttaacgcaat tacaaaagca ggagcagaag ctgctaatta tccttttgcg actattgatc
     1561 ccaatgttgg tatggtagag gttccagatg agcgtctgca aaaattgaca gaattgatta
     1621 cacctaaaaa aacagttccg acaacctttg aatttactga tattgcaggt atcgttaaag
     1681 gtgcttctag aggggaaggt ctaggaaata aatttttagc taatattcgt gaaatcgatg
     1741 ctattgttca tgtggtacgt gcttttgatg atgaaaatgt catgcgtgaa caaggtcgtg
     1801 aggatgcttt cgttgatcct atagcagata ttgacactat taatcttgaa ttaatcttag
     1861 ctgatttaga gtcaatcaat aaacgttatg cgcgtgttga aaaaatggca cgaactcaaa
     1921 aagataaaga atcagtagca gagtttaatg ttttgcaaaa gattaaacct gttttggaag
     1981 atgggaaatc agctaggaca attgagttta cagaagatga agcaaaagtt gttaaaggtc
     2041 tctttttatt aacaactaaa cctgttttat atgtagctaa tgtcgatgaa gataaagttg
     2101 ctaatccaga tggtattgat tatgtcaaac aaattcgtga ctttgcagct actgaaaatg
     2161 ctgaagtagt tgttatctca gcgcgtgcag aagaagaaat ttcagagctt gacgatgagg
     2221 ataaagaaga atttttggaa gctatcggtc ttactgaatc aggcgttgat aaattaacca
     2281 gagcagctta tcatctctta ggccttggaa cctattttac agcaggtgaa aaagaggttc
     2341 gtgcttggac gtttaagcgt ggtataaaag ctccacaagc tgctggtatt atccattcag
     2401 attttgaaag aggttttatt cgtgcagtaa ccatgtctta tgatgatcta atgacctacg
     2461 gttcagaaaa agccgtcaaa gaagctggac gcttgcgtga agaaggaaaa gaatatgttg
     2521 tccaagatgg ggacatcatg gaattcagat ttaatgtgta attatattaa aacaatatca
     2581 gaaggttgga agaacattcc agcccttttg gcattttaga aagagaaaat atggtaaaaa
     2641 tgattgttgg tctgggaaat ccaggctcta aatatgaaaa aacaaagcac aatattggtt
     2701 ttatggctat tgacaatatt gtcaagaacc ttgacgttac ctttacagat gataaaaatt
     2761 ttaaagcaca gataggaagt acttttatta atcatgaaaa agtttacttt gtgaaaccta
     2821 ctacttttat gaataatagc ggcatagcag taaaagcatt actaacctac tataatattg
     2881 acataacaga tttaattgtt atctatgatg atttagacat ggaagtcagt aaattacgtt
     2941 tacgtagtaa gggttcagca ggaggacata atggcattaa gtcaatcatt gcccacattg
     3001 gaactcagga atttaaccga atcaaagttg gtattggacg acctttaaaa ggtatgactg
     3061 ttattaacca tgtgatgggc caattcaata ccgaagataa tattgctatt tcgttaactc
     3121 ttgacagagt tgtcaatgct gtcaagtttt atttacaaga aaatgatttt gaaaaaacaa
     3181 tgcagaaatt taatggataa tcatggatat tttagaatta tttagtcaga ataagaaagt
     3241 ccaatcctgg cactctggat taaccacctt aggaagacaa ctggtaatgg ggttatcggg
     3301 ttcaagtaaa acattggcta tagcttccgc ttatttagat gatcaaaaaa aaatagttgt
     3361 ggttacatca actcaaaatg aggttgaaaa attagccagc gatttatcta gtttacttga
     3421 tgaagaactt gttttccaat tttttgcaga cgatgtggct gcagcggaat ttatctttgc
     3481 gtcaatggat aaagctctat caagaataga aaccctgcaa tttttaagga atcctaaatc
     3541 tcagggcgtt ttaattgtta gtttatcagg cttaagaatt ttattgccaa acccagatgt
     3601 ttttacaaag agtcagattc aactaacagt tggagaagat tatgatagtg atactcttac
     3661 taaacaactg atgacaattg gctatcagaa ggtctcacag gttattagtc caggagaatt
     3721 tagccgtcga ggggatattt tagatatcta tgagattaca caagaattgc cttatcgatt
     3781 ggaatttttt ggcgatgata ttgatagtat taggcaattt catccagaaa ctcaaaaatc
     3841 ttttgaacaa ctagaaggta tttttattaa tccagcaagt gatcttattt ttgaggttag
     3901 tgattttcaa cgtggcattg agcaattaga aaaggctcta caaacagcac aagatgataa
     3961 aaaatcttat ttagaagatg tattagctgt ttcaaaaaac ggttttaaac ataaggatat
     4021 ccgtaaattt caatcattat tttatgaaaa agagtggtca ttattagatt atattcctaa
     4081 gggaacgcca atcttttttg atgattttca aaaactagtt gataaaaatg caagatttga
     4141 tttagagatt gctaatctct tgacagaaga tttacagcaa ggaaaggctc tttccaatct
     4201 taactacttt acagataatt atcgagagct taggcactat aagccagcga ccttcttttc
     4261 aaattttcat aagggacttg gaaatatcaa atttgatcag atgcatcagc taactcagta
     4321 tgccatgcag gaatttttta atcaatttcc tttgttgatt gatgagatta aacggtatca
     4381 aaaaaatcaa acaacggtta ttgtacaggt agagtctcag tatgcttacg aacgacttga
     4441 aaaatctttt caagattacc aatttcgcct tcctttagtg agtgctaatc aaattgtttc
     4501 acgtgaatca caaattgtaa ttggagctat ctccagtggt ttttattttg ctgatgaaaa
     4561 gttagcgtta atcacagagc atgaaattta tcataaaaag atcaaacgac gcgctagacg
     4621 atctaatatt agcaatgctg agcgtttgaa agattacaat gagttagcag taggtgatta
     4681 cgtggttcat aatgtccatg gtatcggtcg ctttcttgga attgaaacga ttcagattca
     4741 gggaatccat cgagattatg ttactattca atatcaaaat tcagaccgta tttctcttcc
     4801 aattgaccaa attagtagct tatcaaagta cgtttctgct gatggaaaag aacctaaaat
     4861 taataaactc aatgatggtc gttttcaaaa gacaaagcaa aaggtcgcta gacaagtaga
     4921 ggatattgct gatgaccttc taaaattata tgctgaaaga agtcagcaaa aaggattttc
     4981 attttcacca gatgatgact tgcagcgcgc ttttgatgat gattttgctt ttgtagaaac
     5041 agaagatcaa cttaggtcta taaaggaaat taaagctgat atggagagca tgcagcctat
     5101 ggatcgtctt ttagtaggcg atgtaggatt tggtaagaca gaagtagcta tgagggcagc
     5161 ctttaaagcg gtgaatgatc acaaacaagt agctgtctta gttccaacca cagtcttggc
     5221 ccagcagcat tatgaaaact tcaaagcacg ctttgaaaat taccctgttg aggttgacgt
     5281 cttaagtcgt ttccgtagta aaaaagagca agctgaaaca ctagaacgtg tacgaaaagg
     5341 tcaaattgac attattatcg gaacccatcg actcctatca aaagatgtgg tcttttctga
     5401 tttaggattg attgtgattg atgaggaaca acggtttggt gttaagcata aagaaacttt
     5461 aaaggaatta aaaactaagg ttgacgtctt aaccttaaca gctactccga ttcctagaac
     5521 cttacacatg tctatgttag gtatccgaga tttatcggtt attgagaccc caccaaccaa
     5581 tcgttatcct gttcaaacct atgttttgga aaataatcca ggtctcgtta gagaagctat
     5641 cattcgtgaa atggatcgcg gaggacaaat tttttacgtt tacaataaag ttgacactat
     5701 tgaaaagaaa gttgcagagc tacaagaatt agtcccagaa gcttctatag gttttgttca
     5761 tgggcaaatg agtgaaattc aacttgaaaa taccttgatt gactttataa atggtgatta
     5821 tgatgtcctt gtggctacaa caatcatcga aacaggagtt gacatttcta atgtaaacac
     5881 tttgtttatt gagaatgctg atcatatggg attgtcaact ttatatcaac tacgagggcg
     5941 cgtcggaaga agtaatcgta ttgcttatgc ttacctgatg tatcgtcctg ataaggtcct
     6001 aacagaggtt tctgaaaagc gtttagaggc tattaaaggc tttactgaat taggttcagg
     6061 cttcaagatt gctatgcgag atttgtctat acgaggagca ggtaatattt taggggcttc
     6121 tcagagtggc tttattgatt cggtcggttt tgaaatgtat tctcagttat tggaacaggc
     6181 tattgctagc aagcagggaa aaacgactgt tcgtcaaaaa ggcaatactg aaatcaatct
     6241 tcagattgat gcctatttac cagatgatta tattgcagat gagcgccaaa aaattgacat
     6301 ttacaagcgt attcgagaaa ttcaatcaag agaagattat ctcaatttgc aagatgagct
     6361 tatggatcgt tttggagagt atcctgatca agttgcctat ttgttagaga tagctctgct
     6421 aaaacattat atggacaatg cctttgcgga attagttgaa cgcaaaaata atcaggtcat
     6481 tgttcgattt gaagtaactt ctttaactta tttcttgact caggattatt tcgaagcctt
     6541 atcgaaaacc catcttaaag ctaaaattag tgaacatcag gggaaaatcg atatcgtctt
     6601 tgacgttcgc catcaaaaag attatagaat tttagaagaa ttgatgttat ttggagaaag
     6661 gcttagtgag ataaaaatca gaaaaaacaa ttcagttttt aaataataat ttgaaacaac
     6721 ttttagactg aatagtatta atgacaatgg aacgaactag ctctttatac ttttgtcaaa
     6781 aatctaagat ctttgctgcg aaattaggat cttttctacc atttaaaaaa taaaaatgat
     6841 aaaatgaaga ggattgtagg agaaattatg agactagata aatatctaaa ggtatcgcgc
     6901 cttattaaac gtcgttcagt agcaaaagaa gttgcggata agggacgaat taaagttaat
     6961 gggatacttg ctaaaagttc aacgaatata aaactaaatg atcacattga aattagtttt
     7021 ggaaataaat tactgacagt aagagtcatt gaaataaaag atagtacaaa aaaagaagat
     7081 gctcttaaga tgtatgagat aatcagtgaa acaaggataa cattaaatga agaagcctag
     7141 tattgttcaa ttaaataatc attatattaa gaaagagaat ctcaaaaaaa aatttgaaga
     7201 agaagaatct caaaaaagaa atcgttttat gggatggatc cttgtaagta tgatgttttt
     7261 atttattttg ccaacttata atcttgtcaa aagttatgtt gattttgaaa agcaaaatca
     7321 acaggtggtt aaattaaaaa aagagtataa tgaattgtca aagagtacaa aaaaagaaaa
     7381 acaattagca gaacgactaa aagatgataa ttttgtcaaa aaatatgcta gggcaaaata
     7441 ctatttatcg cgtgaaggag aaatgattta tcctattcca ggactattac caaaatgatg
     7501 atggacaata ttgtaaaaaa aatagaagca tttcttgctt tttctgataa aaaattagca
     7561 gagctgcaac aggaaaatca aaaagttaaa gaagaaagtc agtatattca aaaaaactag
     7621 aaaggagtca atatgagaaa attattagcg gctatgttaa tgactttttt tctgactcct
     7681 ttaccagtga ttagtacaga aaaaaaactt atattttcaa aaaatgctgt ttatcaattg
     7741 aaacaagatg tcgttcaatc aacacaattc tataatcaaa taccctctaa tccaaatctt
     7801 tatcaagaaa cgtgtgccta taaagacagt gatttaactc taccagcagg aagattaggt
     7861 gtaaatcaac cattacttat taaatcgctt gtgcttaaca aagaatcttt accggttttt
     7921 gagttagctg atggtaccta tgttgaggct aatcgacaat tgatttatga cgatattgta
     7981 cttaatcaag tagatataga tagctatttt tggacacaaa agaaacttag gctttattca
     8041 gccccttatg ttttaggtac gcaaacaatt ccttcttctt ttttatttgc tcaaaaagtt
     8101 catgccactc aaatggcaca aacaaaccat ggaacttatt atcttattga tgataagggc
     8161 tgggcatcac aagaagatct agttcaattt gataaccgca tgttaaaagt ccaggaaatg
     8221 ctcttacaaa aatataataa cccaaattat tcaatttttg taaagcaact caacacacaa
     8281 acaagtgctg gtattaatgc tgataaaaaa atgtatgctg caagtatctc gaagttagca
     8341 ccactttata ttgttcaaaa acaattacaa aaaaagaaat tagcagagaa taaaactttg
     8401 acttatacta aagatgttaa tcatttttat ggagactatg atccattggg aagtggtaaa
     8461 attagtaaaa tagctgataa taaagattat cgtgttgaag acctactgaa agctgtagca
     8521 caacaatcgg ataatgtagc aactaatatt ttaggttatt atctatgtca tcagtatgat
     8581 aaagctttcc gctcagagat aaaagcttta tcaggtatcg attgggatat ggagcagcgc
     8641 ttattaactt ctcgttcagc tgcaaatatg atggaagcta tttatcatca aaaaggccaa
     8701 attatttctt acctttcaaa taccgaattt gatcaacaac gtatcacaaa aaatattact
     8761 gttccagttg cacataaaat tggtgatgct tatgattata aacatgacgt tgctattgtt
     8821 tacggtaata ctccatttat tttgtctatt tttacaaata aatcaaccta tgaagatatt
     8881 acggctattg cagatgacgt ttatggtatt ttaaaatgat gacctatcaa gaaattttta
     8941 atgaaataaa aaataaagcc tactttaaaa atcatagaca tgtgttaata gccgtatctg
     9001 gtggagtaga ttcaatgaat ttattgcact ttttatacct gtttcaagac aaattgaaaa
     9061 ttcgtattgg tattgctcat gttaatcaca aacaaagatc agaatcagat tcagaagaag
     9121 cttatttaaa gtgttgggct aaaaaacatg acatacctat ttatgtttct aattttgaag
     9181 gaatattttc agaaaaagca gcacgtgatt ggcgctatgc tttttttaag agtattatgt
     9241 taaaaaataa ctattcagct ttagtaacag ctcaccattc agatgatcaa gcagaaacta
     9301 ttttgatgag gctaattaga ggaagccgat tgaggcactt gtcgggtata aaaagcgtgc
     9361 aaccatttgc caatggtcaa cttataagac cttttttaac tttctcaaaa aaggacttgc
     9421 cagaaatttt tcattttgaa gattcttcaa atagagaatt atcattttta agaaatagag
     9481 ttagaaataa ttatttacca ctgttaaagc aggaaaatcc taggttcatt cagggattaa
     9541 atcaattagc acttgaaaat agcttacttt ttcaagcttt taaggagcta acaaatcata
     9601 ttactaccac tgatttaaca gaatttaatg agcaatctaa gtcaattcaa tactttttgt
     9661 tacaagatta tttagaaggt tttccagatt tagatttaaa aaaatctcaa tttactcaat
     9721 tattgcaaat tatccaaact gctaaacaag gctattatta tct
//
LOCUS       DAUGQX010000051         9444 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUGQX010000051 DAUGQX010000000
VERSION     DAUGQX010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9444
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.051"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..133)
                     /locus_tag="VIA51_001503"
     CDS             complement(<1..133)
                     /locus_tag="VIA51_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8683441.1"
                     /translation="MKRIIKTIILVIIIFHGYGSVKSDSENIKDVKLQLNYAYEIIPV
                     "
     gene            complement(381..995)
                     /locus_tag="VIA51_001504"
     CDS             complement(381..995)
                     /locus_tag="VIA51_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683442.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDEQNKFILDGLQEKVKEVSVS
                     DFSVGESKIKVWLPQAWSVKISREHSPKSSISNSGEQKPLSNSSENKEGQFSKRLPYG
                     TQHTIKLSSQLTKGERVTLTFRDEDFWGAGYCFYRDSLSIKEDKQYEEEIKKIEDDLE
                     RQDLENDALEMFKKQTEREANKPWHQRLSENIQDQWWNFKGLFQ"
     gene            1356..1592
                     /locus_tag="VIA51_001505"
     CDS             1356..1592
                     /locus_tag="VIA51_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEQ8683443.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            1585..2283
                     /locus_tag="VIA51_001506"
     CDS             1585..2283
                     /locus_tag="VIA51_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEQ8683444.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLKQGHHVYGVDKSDKPDLSGNF
                     HFIKLDLSSELAPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTANDFEPGGLADWVARETPIGRWTKPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            2359..3318
                     /locus_tag="VIA51_001507"
     CDS             2359..3318
                     /locus_tag="VIA51_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8683445.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTAKDLA
                     KAHHMPLATSKYEAILGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIARKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVQLSLHGHEPQVINHNKH
                     DHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMAVLERAVHS"
     gene            3651..4988
                     /locus_tag="VIA51_001508"
     CDS             3651..4988
                     /locus_tag="VIA51_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8683446.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIAILLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKVGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            5161..6543
                     /gene="glmU"
                     /locus_tag="VIA51_001509"
     CDS             5161..6543
                     /gene="glmU"
                     /locus_tag="VIA51_001509"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEQ8683447.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALAIAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            6574..7128
                     /locus_tag="VIA51_001510"
     CDS             6574..7128
                     /locus_tag="VIA51_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8683448.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLIQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            7128..7379
                     /locus_tag="VIA51_001511"
     CDS             7128..7379
                     /locus_tag="VIA51_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683449.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVNFDTKVMTLPEKDDKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            7399..8094
                     /locus_tag="VIA51_001512"
     CDS             7399..8094
                     /locus_tag="VIA51_001512"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEQ8683450.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQTLMTFLENLPV"
     gene            8245..8586
                     /locus_tag="VIA51_001513"
     CDS             8245..8586
                     /locus_tag="VIA51_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683451.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNEGYHQHLTD
                     EKSHLQYSKDNAQLQLRNILDGYQNDLGRHYSSYYYYNLRTVMGLSSEQDIEKHYEEL
                     KNKLHDMYNHY"
     gene            complement(8687..9334)
                     /locus_tag="VIA51_001514"
     CDS             complement(8687..9334)
                     /locus_tag="VIA51_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEQ8683452.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDSFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
BASE COUNT         2728 a         1721 c         2101 g         2894 t
ORIGIN      
        1 ctactggtat gatttcgtat gcgtaattta attgtagctt aacgtcttta atattttcac
       61 tatctgattt tacacttccg tacccatgaa agattattat aactaaaatt attgttttta
      121 ttattctttt catacctctc ctcgttcacc tcgtacccca caaactactt tatcctaaaa
      181 aaccataaaa tcaacattga ggactttttt ggttcccata aattgttaac tatgtcattt
      241 tagagcaatc atatagagac taagatataa ttttaccaaa gttttgaaag ctattgaaga
      301 gtatcttgat tttgtctagg ttctaagcac ctgtaagggt gctttttgtg ctttagccaa
      361 cctcatagtc tagtaaaccc tcactgaaac agtcccttaa agttccacca ctgatcttgg
      421 atgttttcgc ttaaccgctg atgccaaggt ttattagcct ctctttcggt ttgtttttta
      481 aacatctcta gtgcatcatt ttcaagatct tgtctctcta ggtcatcctc aattttctta
      541 atttcttctt cgtattgttt gtcttctttt atggatagtg aatctctata gaagcagtaa
      601 cctgctcccc aaaaatcttc atctctgaat gtcaaagtga ctctctcacc ttttgtaagt
      661 tgggatgata atttaatagt atgttgggta ccataaggta atcttttaga aaattgacct
      721 tctttattct ctgagctatt gcttaaaggt ttttgttctc cagaattaga aatgcttgat
      781 tttggtgaat gttctctaga aattttgacc gaccaagctt gaggaagcca gactttgatt
      841 ttagattctc caacagaaaa atctgataca ctaacttctt ttactttttc ctgtaatcca
      901 tcaagtataa acttattctg ttcatcctcc gctctgacgc tactagttac cccgatggca
      961 aagagtgcca gtagcaaggt taatgttttt ttcatttttt cctctccttt tgctcatttt
     1021 taagataaga cttattatac caattcttgc gctaaaaaga tagggagttt atgtcttgtg
     1081 gttgggaaat ggcgtgacta ttcttggtag gggcagacag gttttttcct agccagttgc
     1141 taaccgttac ccttttacct ttgcaagccg tttgggcatc aggtcgtgtt ttgaggttgc
     1201 caatactttt agttgctttt tgacaaaaat gcgttatgat agactaaata aaagaagata
     1261 gcattttcga tgaatgatgc gtgagtccac aaatttattt ttaggagttt atagactgcc
     1321 taaaagtgtc tatttcgtca ataaaggaga acaatatgac atttgaagag attttaccag
     1381 gtttaaaagc caagaaaaaa tatgtacgta caggttgggg tggcgctgaa aattatgtgc
     1441 agttgtttga tacccttgaa gtggatggga aagtactaca ggcgacgcct tattttctga
     1501 ttcatgttac tggtgcaggt gaaggttttt ccatgtgggc accgacacca tgtgatgtgt
     1561 tagcagagga ttggattgag gtcaatgact aaagttgttt tagtgacggg ctgtgctagt
     1621 gggattggtt atgcacaggc ccgctatttt ttgaaacaag ggcatcacgt atatggtgtg
     1681 gataagtcgg ataaaccgga cttaagcggt aactttcact ttatcaaatt ggatttatcc
     1741 tctgagttag ccccactatt taaagtggtc cccagtgttg atattttgtg taatactgca
     1801 gggattttag atgcctacaa gccactttta gacgtcagtg atgaagaagt ggaacaccta
     1861 tttgatatta atttttttgc gacggtgaag ttaacacgtc attatcttag acgtatggtg
     1921 gaaaagcagt caggtgttat catcaatatg tgctcaatag caagttttat agcgggtggc
     1981 ggtggtgttg cctatacgag ttctaagcat gcccttgcgg gattcacgcg ccagctggct
     2041 ttggattacg ccaaagatca gattcacatt tttggtatag caccaggtgc tgtcaaaacc
     2101 gctatgacgg ctaacgattt tgagcctggt ggcttagcag actgggtagc tcgtgagacg
     2161 ccaattgggc gttggactaa accagatgaa gttgctgaat taacgggatt tcttgcttca
     2221 ggaaaagcga gatcaatgca aggcgagatt gtcaaaattg acggtggctg gactttgaaa
     2281 tgatcacatg ccttagcttg agctggcgca gtaagcccta gaggtgtgat gagtcaaaca
     2341 gtcaaaggag atgaacaaat gaaattagcg gttttgggga caggtatgat tgttaaggaa
     2401 gttttgcctg tcttgcagaa aattgatggt attgatttag ttgctatctt atcaacagtt
     2461 agaagtttaa cgacagctaa agacctcgct aaggcacatc acatgcctct agctacgagt
     2521 aaatatgagg ctatcttagg caatgaggag attgacacgg tttatattgg actgccgaat
     2581 cacctgcatt ttgcctatgc taaggaggcc cttctagctg gcaaacatgt catttgtgaa
     2641 aagcccttta ccatgacagc aggagaatta gatgaactgg tggtaatcgc tagaaaacga
     2701 aaactcattt tgttagaagc gattacgaat cagtacctga gtaacatgac ctttatcaaa
     2761 gagcatcttg accaacttgg cgatatcaaa attgtagaat gcaattattc acaatattct
     2821 tcacgctacg atgccttcaa acgaggtgat atcgcgccag cttttaatcc taaaatgggt
     2881 ggtggagctt tacgtgattt aaacatctac aacattcatt ttgtggtagg gttatttggt
     2941 cgccctaaaa cggttcaata tttagccaat gtcgaaaaag gcattgacac ctcaggcatg
     3001 cttgtcatgg actatgagca gtttaaagtg gtgtgtatcg gggccaaaga ctgcactgca
     3061 gaaatcaaat caaccatcca aggtaacaaa gggtcactgg cagtgcttgg agcaacaaat
     3121 accctccctc aggttcagtt aagtctacac ggtcacgaac cacaagtgat taaccacaac
     3181 aagcatgacc accggatgta tgaagagttt gtcgctttta gggacatgat tgaccaaaga
     3241 gactttgaga aagtgaatca ggctttggaa catagccgag ctgtcatggc tgtgttggag
     3301 cgcgctgttc attcgtgatg gtaatctggt agccattgcc ttttgtgcag gtgctatggt
     3361 aatggttgaa agacgtgttt tcacgagggg gagccccctc gtgctttttt ggcaaaaata
     3421 acttgttcag gatttgggct ttctttgtga gatgagagat gcctgacgaa ttgatttgat
     3481 taaaataatg ataaagccaa acgatttaag aaatgaccgt tcggaaattc tgccccaaag
     3541 gggctctaga agcagtaaaa tcgaatttgt aagcgttgac actgttgcat aactctgtta
     3601 cactaagaga atgtcatgac aaaaattaca gtgtaggagt ttaattgttt atggaagagg
     3661 attataacaa aagagaacct gagaagttta cgcaatttct gcgccgtcaa aaggtcgtct
     3721 tttttgtcgc attttttggt tatgtgtgtg cttacttggt acgcaacaat ttcaaactaa
     3781 tgtcaaacac tattatggtg caaaatggtt gggacaaggc tcaaattgcg atcttgttat
     3841 cgtgtttgac cgtttcttat ggcttagcaa aattctatat gggagcctta ggggatcgtg
     3901 ttagcttgag gaagctcttt tcaatcagct tgggtgcaag cgctttgatt tgtattttaa
     3961 ttggtttttt caatagttca atggtggtat taggaatact gctagtcttg tgtggtgtcg
     4021 tacaaggtgc cttggcacct gcctcacaag ccatgattgc caattatttt ccaaataaaa
     4081 cacgcggcgg agccatcgct ggatggaaca tttctcaaaa catgggatca gccctcttgc
     4141 cattaaccat cgccttgctc accagtatgg gcttggtggt accagctaat ggcaatattt
     4201 tacttgcctt tttaatccct ggcgttttag tgttcttgtt tgctttgtgt tgctggaagc
     4261 ttggcggtga taaccctgag tctgagggac ttgactctct tcgaacgatg tatggtgatg
     4321 cgggcgagtc agctgttgcc agtgaagaag aaaagcataa cctgtcttat tggcaactca
     4381 tctggaaata cgttttttgt aacccgtcgc tcttacttgt tgctgctgtc aatgtggccc
     4441 tttattttgt tcgttttggg attgaagact ggatgccgat ctacttgtca caagtagcca
     4501 atatgtcaga ggctcatatc cattttgcga tttcaatgtt agagtgggtc gctattccag
     4561 gctcgctggt atttgcgtgg ttagcggttc gttatcctaa taaaatggcc aaggttgggg
     4621 ctattgggct ttttgtgtta gcggctattg tctttgtcta tgaacgcttg actgccacag
     4681 gtgctccaaa ttatttcttg ttgcttgtta ttgcaggtat tttagggtca ttgatttatg
     4741 gcccacagtt gatcgtgaat attttaacaa tcaactttgt tcctttaaat gttgcaggaa
     4801 cagcgattgg ttttgtagga gtaacagctt atctcatcgg caatatggga gcaaactggc
     4861 tgatgccgat tttggcagat ggttttggct ggttttggtc atatattgtc gttgcagcct
     4921 tatctgcttt ttcagcggtt ggttatttga ttttagccaa acgtgaggaa gaaatcatca
     4981 aagattagct aggcaaatgc ctaagaaaga cagacttatt gctgaagtcc tgtctttttt
     5041 agttatcaca agccgcaaat gacactataa aagacaagaa aatgctagga tgtttcagga
     5101 aaaaaagaga aaatatgcta taatgagaag gtatttaaat tatatagtaa ggaaaaacaa
     5161 atgacaaatt atgccattat tttagcagcg ggcaaaggga ctcgcatgac ttctgatctc
     5221 ccaaaagttc ttcataaagt atctggacta accatgcttg agcatgtttt tcgtagtgta
     5281 aaagcgatta gtcctgaaaa atccgtgacg gttattggtc acaaatcaga aatggtacgt
     5341 gctgtcttag cagatcaatc agcctttgtc catcaaacag agcagttagg aactggccat
     5401 gccgtgatga tggcagaaac acaactagaa ggactagaag ggcatacctt ggtgattgca
     5461 ggagatactc ccttgatcac tggagaaagc ctgaagagtc tgattgattt tcatgtgaat
     5521 cataaaaatg tcgccactat tttaacagct acggctcaag atccatttgg ttatggtcgt
     5581 attgttcgca acaaagatgg cgaagtgatc aagattgttg agcaaaaaga cgccaatgag
     5641 tatgagcaac aattaaaaga aatcaataca ggaacctatg tgtttgataa caagcgtctc
     5701 tttgaagcgc tcaaatgcat cactaccaac aatgctcaag gagagtatta cctgactgac
     5761 gttgtggcta tttttagagc aaacaaagaa aaggtaggag cctatatcct gagagacttc
     5821 aatgaaagtc tgggagtaaa tgatcgtgtg gccttagcaa tagctgaaac agtgatgcgt
     5881 cagcgcatta cccaaaaaca tatggtcaat ggggtgactt tccaaaatcc tgaaactgtt
     5941 tatattgaaa gcgatgttga gattgctcca gacgtcctta tcgaaggaaa tgtgacctta
     6001 aaagggcgta cacatatcgg ctcaggaact gtcttgacga atggtactta tattgtggat
     6061 tctgaaattg gtgataactg tgttgttacc aattcgatga tcgaatcatc tgttttagct
     6121 gcaggagtta cggttggccc ttacgcccac cttcgaccgg gaacgacctt agatagggaa
     6181 gtccatatcg gtaactttgt cgaggtcaag ggttctcaca ttggtgaaaa aacaaaggct
     6241 gggcatctga cttatattgg aaacgctcag gttgggtctt cagtcaatgt tggggctgga
     6301 accatcactg tcaactacga cggccaaaac aaatatgaaa cagtcattgg agatcacgct
     6361 tttattggga gcaactcgac tctcattgca cctttggaag ttggggatca cgctttaaca
     6421 gcagcaggtt caacgatttc aaaaacagtt cctatcgata gcattgctat tggtcgtagc
     6481 cgccaagtca caaaagaagg ttatgccaag cgcctagcgc atcacccaag tcgaagcaaa
     6541 taattcaaga tctatttagt aaggaggcca ggcatgaaat ttgaagaaaa aacgcttaag
     6601 agacaaacag tttttgatgg tcatattttt aaagttgttg tggatgatgt tgaacttccc
     6661 aacaatctgg ggcaatccaa gcgagaatta atttttcatc gtggtgccgt tgctgttttg
     6721 gctattactc ctgaacgtaa gattgtcctt gtcaaacaat accgtaaggc tattgaacgt
     6781 gtctcatacg agatcccagc gggtaagcta gagattggtg aggaaggctc aaagctaaaa
     6841 gctgctgcac gtgagctaga agaagaaaca gcctatacgg ggacattgac gtttttgtat
     6901 gaattttata cagcgattgg tttttgcaac gaaaaaatca cacttttctt agcgacagac
     6961 ctaatacaag ttgccaatcc caaacctcaa gacgacgatg aagttatcga ggtcttagag
     7021 ttgacatatc aagagtgcat ggacttagtc gctcaaggta aacttgctga cgctaaaacg
     7081 ttgattgctt tgcaatacta tgccttacat tttggaggtg agcagtgatg ggaaggccat
     7141 tgttgaccga tgatatcatc gaaaaagcga gacgaatgga aacatttgag ccagatgatg
     7201 ctgtaaactt tgacacaaaa gtaatgacgc taccagaaaa agatgataaa gcacgcattt
     7261 ataaaagtcg tcggattgaa aatgccaaac gcagccaatt gcaatctaaa ttaaatgtga
     7321 ttttgatagc tgttatgctg ttaattgcca tcttggtata tgctatcttt tatctttaaa
     7381 aaaacgtaag gaaatgatat gaaaatagga attattgctg ctatggagga ggagttgtcc
     7441 ctgctcttag caaatctttt ggatgctcaa gaacatcagg tgctttcaaa aacttactat
     7501 acgggtcgtt ttggcaagca tgagctcatt ttggtacagt cgggtgttgg aaaagtgatg
     7561 tctgctatga cagttgcgat cttggttgag catttcaaag cccaagctat tatcaataca
     7621 ggatcagcag gggcagtcgc ttcacattta gcgatcggag atgtggtggt tgcagatcgg
     7681 ttagtgtatc atgatgtgga tgctactgca tttggttatg cttatggtca aatggctggt
     7741 caaccattat actatgattg tgatccacag tttgtggcta tcttcaaaca agtcctaaaa
     7801 cacgaaaaga caaatggcca agttggtttg attgcaacag gagacagttt tgttgctggt
     7861 caggacaaga ttgaccagat caaaacagct tttagcgacg tgttagcagt agaaatggaa
     7921 ggcgcagcta ttgctcaagc agcacatact gcagggaaac ccttcatcgt tgttcgtgcg
     7981 atgagtgata ccgcagcgca tgatgccaat attacttttg atcaatttat tatagaagct
     8041 ggcaagcgtt cggcccagac attaatgaca tttttagaaa acttacctgt ttaactcact
     8101 ttatcgtgag acaattagct ggataatctc tattttagga gtctggtcac ttcttgtttt
     8161 gaaacctaaa aataagaatt gcaatcactt gaccaaacgc tataatgggt taagtaacga
     8221 tagattacta aaaggagtct aaaaatgaca ctaaaaaaac actattatct tctcagcctg
     8281 ctagctcttg taacggttgg tgctgccttt aacacaagcc agagtgtcag tgcacaagtt
     8341 tatagcaatg aagggtatca ccagcatttg actgatgaaa aatcacacct gcaatatagt
     8401 aaagacaacg cacaacttca attgagaaat atccttgacg gctaccaaaa tgacctaggg
     8461 agacactact ctagctatta ttactacaac ctaagaaccg ttatgggact atcaagtgag
     8521 caagacattg aaaaacacta tgaagagctt aagaacaagt tacatgatat gtacaatcat
     8581 tattaagtca aaggcttaaa aatggcgact agcccctcaa aaaaagaggc cacactcatt
     8641 taaatttaaa tgagtgtggc ctcttttttt gaggagacgc aaggggttaa agggctgtga
     8701 cataaagttg cttagcaata ttttcaggga tgacaagttc cttgtcgcca taacaaatcg
     8761 tataggtttt tgcaaaggta tcaatttgag ttaaggttag ctcggtattg atattgaggt
     8821 gatgtgcttc tagatactgg attaaatcaa agtggtcgtg gattctgctt agacgaaacc
     8881 gtcccaactc cgtgatggtg ttgagagttg tagtgttcat ttcgacaaga ggctgaccat
     8941 agcgaggaat agtccctccg tgtgggcaga aatctggaaa atcaaggatc ttgtctaaac
     9001 ggtcgataaa ggagtctgag acagtgtgct ctaagacttc agcttcttgg tgcacttctt
     9061 gggtattata gcccagctga tgaatcaaaa atacctcaat caagcggtgt ttgcggtaga
     9121 ggttagcaac aagagcatag cctttgtctt ttagcaaata gccttttgct ttatctttga
     9181 caatccagcc ttgtgaaatc atttttttaa tcatctctga aacggcaggt gccgaaacgt
     9241 gcatcttttc tgcaaccatt ttatttgtaa tcttgggttc ttgttctcca atttcataaa
     9301 tacatttcaa gtaatcttct ttattaggcg tcatatcgtt tggcctttct cttatttata
     9361 atgattatta tatcagaatt tttaggaaaa agcttgacaa aaagcctaaa agaggatatc
     9421 cttatagcat aattaactaa actt
//
LOCUS       DAUGQX010000052         9277 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUGQX010000052 DAUGQX010000000
VERSION     DAUGQX010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9277
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.052"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(184..279)
                     /locus_tag="VIA51_001515"
     CDS             complement(184..279)
                     /locus_tag="VIA51_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEQ8683453.1"
                     /translation="MCEAIFTTIIAPLLVGIILLLIQKWLDDSAD"
     gene            915..1106
                     /locus_tag="VIA51_001516"
     CDS             915..1106
                     /locus_tag="VIA51_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683454.1"
                     /translation="MPDNTIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            1118..1834
                     /locus_tag="VIA51_001517"
     CDS             1118..1834
                     /locus_tag="VIA51_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEQ8683455.1"
                     /translation="MNQIINITVNDNHEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQVEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRANGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            1866..2132
                     /locus_tag="VIA51_001518"
     CDS             1866..2132
                     /locus_tag="VIA51_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683456.1"
                     /translation="MEEKKFFTTYEMDLMNSVVTLQKSILTQTEHLSDQLTKKLHHLE
                     DYNSPIDDEAIRLAEVTAEFYKLLIKSPSVGATVKEIVSEGHKR"
     gene            complement(2067..2873)
                     /locus_tag="VIA51_001519"
     CDS             complement(2067..2873)
                     /locus_tag="VIA51_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HEQ8683457.1"
                     /translation="MLNIDTQFVDTIGKILSDYVSHSEITRMGEVLGYPQNDQNSGFN
                     KHKRVHNLMSDILNRTQNTDNIKLVIEYVCNPLRYINEVSIFEQLRTAINIPLSLKGL
                     IVSDSGQIVTTTTSKTLSEAKKRFETLDSRLKELKVHPHVLKFCTQELLQENYFHAVF
                     EASKGVFHRIRLLTGSAMDSASLIDQCFKPGEPIVIINGNKLQTLDEQSEYKGLKNLL
                     LAIAHLYRNSKAHKLKYYNPDNLNDALTALTLMSLAHNLLDSCSNTRRLD"
     gene            complement(3015..3254)
                     /locus_tag="VIA51_001520"
     CDS             complement(3015..3254)
                     /locus_tag="VIA51_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683458.1"
                     /translation="MDTKEFMKVVSKHINQNFNVDNQLVEFVVAELNQMNAPITQKQA
                     QHIVNILEYVSKSTSKSTIAAMTNALLELGVLKGD"
     gene            3421..3606
                     /locus_tag="VIA51_001521"
     CDS             3421..3606
                     /locus_tag="VIA51_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683459.1"
                     /translation="MWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKFD
                     DVVKIADVLGVSLDEFR"
     gene            3684..3995
                     /locus_tag="VIA51_001522"
     CDS             3684..3995
                     /locus_tag="VIA51_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEQ8683460.1"
                     /translation="MPKAEITYRAVDVNETASHGDYKHLIQQWEGLTVATAKQWATEM
                     RDHPDFKQFVLNPTHRIVFIDYEGFKLFVQWKSRNRYKTKKETLSEMLENIKFEKRVG
                     A"
     gene            3997..4182
                     /locus_tag="VIA51_001523"
     CDS             3997..4182
                     /locus_tag="VIA51_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683461.1"
                     /translation="MNKLELFLLVTTIILAIITRVQHEVIKKHNSPENKRRIFREVAL
                     ENSKGWREKRSGGKVVS"
     gene            4666..5055
                     /locus_tag="VIA51_001524"
     CDS             4666..5055
                     /locus_tag="VIA51_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEQ8683462.1"
                     /translation="MTKKELFENFQKNWMRLLSPFEIEDIDKWIDEDNMPVEVVNEAL
                     KETVIYNAPNLRYLNRVLNNWKRQGIDTVEKVEFARLQFENKKLSQNKNQQSNVPSWS
                     NPDYKEPDLKEFALGSMDGIEDGSGDF"
     gene            5036..5269
                     /locus_tag="VIA51_001525"
     CDS             5036..5269
                     /locus_tag="VIA51_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683463.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKNGVKP
                     IFNWINLYAFGTGMTTAEADRLRIERYKQENVL"
     gene            5266..5406
                     /locus_tag="VIA51_001526"
     CDS             5266..5406
                     /locus_tag="VIA51_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683464.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            5415..5621
                     /locus_tag="VIA51_001527"
     CDS             5415..5621
                     /locus_tag="VIA51_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683465.1"
                     /translation="MTPEQAEKAKIRAKQELETFSIYLDQAIDELGGVLTSREVFLAA
                     GITYLGAGQTDIHAAVEGLCEQIQ"
     gene            5677..6006
                     /locus_tag="VIA51_001528"
     CDS             5677..6006
                     /locus_tag="VIA51_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683466.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNKKDVLAYNVELTDSIQLASF
                     LPEEAYNIQKEKIDNLAETLGCDVVVIEASYDLKFIDGEDVPELTKEQKVKSMVNGMF
                     EQVFGGE"
     gene            6009..6938
                     /locus_tag="VIA51_001529"
     CDS             6009..6938
                     /locus_tag="VIA51_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEQ8683467.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIEEDNQDST
                     ISTPKDITPQEANSLDDLIGHQNENKDAPNNLKDVTEDLHDEEEKTLADENKTALEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLMP"
     gene            6935..7732
                     /locus_tag="VIA51_001530"
     CDS             6935..7732
                     /locus_tag="VIA51_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEQ8683468.1"
                     /translation="MTKLDLLGKDYYSRESAIKYWSISQYKRFRECEARALAELRGGW
                     TDTRDNTALLVGNYVHSYFESKAAHEEFKAQNDSEMISTRGTTKGQLKKDYLVAEQMI
                     EALKNDSNFMAIYQGEKEAAITGFLGEVEFKGKIDCLNVERGYFVDIKTTKGPIDDTI
                     WNREERVRWFEAYGYILQMAAYKTMLEAKYNKPFKPIIYAVTKETPPDTRAIRIQNVD
                     AMQNELDDLAQNIKHLDDVKKGLEKPKPCGHCEYCRANQLTQRVMIF"
     gene            7742..7909
                     /locus_tag="VIA51_001531"
     CDS             7742..7909
                     /locus_tag="VIA51_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683469.1"
                     /translation="MTKYYVSAKIANLDIGAETEAENQHMAPIAFKETYDHLLRFGSH
                     KLIILGVEELN"
     gene            8087..8428
                     /locus_tag="VIA51_001532"
     CDS             8087..8428
                     /locus_tag="VIA51_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683470.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGSLTMQWDFISGFKKIDDE
                     PSLDEDGELFETAYDLILAAKPKTKINLTSSYFAKEHKKDIDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            8425..8937
                     /locus_tag="VIA51_001533"
     CDS             8425..8937
                     /locus_tag="VIA51_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683471.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSKSYFERGRY
                     MASQLRLIQSRALKKYDCYFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKYWKFSYKDRSKKSMKLQSKIKVEQEFNKSVKDDEADAILIGSYYVNQGY
                     LDELETHDYY"
     gene            9021..>9277
                     /locus_tag="VIA51_001534"
     CDS             9021..>9277
                     /locus_tag="VIA51_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683472.1"
                     /translation="MTEEQMIDCLLYELVKKDKAIKKKSIIIAALTVMLIVVSGLCVS
                     LKSYYEPQIYGLRTQLSRTQKQLKRASEQNQRQTKRIADLT"
BASE COUNT         3344 a         1542 c         1877 g         2514 t
ORIGIN      
        1 aatgtcaatg aaaaatttaa atttttacta actttattac ttacaagttc tttgacaatt
       61 gaatatcgta tgtgatatga tataggggaa gtgaagatag tttcgtcgcg cataggcgaa
      121 cataaaaacc ccttgcaaaa tcctacaaat gcaaggggtt ttttctattt tgcaatagaa
      181 gcactaatca gcactgtcat caagccattt ctggattaat aacaggatta ttccaaccaa
      241 tagcggtgcg ataatagttg tgaagatagc ttcgcacata gacgtcacct ccttagctaa
      301 ggcaggtata gtagtgccag tcaatattat atcatgtacg ttatcgattg gatagcgtac
      361 ttttttgttt aaaagtataa aacaccacct agctgctatc tagatggtgc tacggaaatt
      421 attctgctcg aaatgaaaat gctagagtgt ccgatactct agcacccacc aattttgatt
      481 agctctctgc ccatcggaca gacaaaacaa atcttcgctg gattgggaac cagcactgca
      541 tggtttatag gtagcaacaa cgactctata cccctaagtc gaataacggc aatattttta
      601 cgtgtcatgc caccactcca tctatctcta atttaaagtg atagacattt tcgacttaga
      661 ttcattccta gttttgcgcg tctagtccgc ttcggctccg agtagagcaa tgtgtctatt
      721 tacctatgag agcacagtac ctttcaaaaa ttctgctaac aataacatca gctcctttct
      781 gtaataaagg tactttcatt ataagattgt aagtcaaaaa aatcaagatg gttacaaaaa
      841 ttattgagca gaataacgat ttccgtatat tttattaata ttttctactt atttttgaaa
      901 aaggaggtat acaaatgccc gataacacaa tcgccatcga aaaaattaaa aagtatttgc
      961 ttgataacaa ccttaaacaa gttgatctag cagttactta tggcaaagaa ccgcaagatg
     1021 tggcgaacat tcttgctgga cgaaaaaaag acccagcatc aaatcgcttt gttttaaaag
     1081 ttatttcaga tttaaaaatc agatagaaag gcatcaaatg aatcaaataa tcaatattac
     1141 agtaaacgat aaccatgaac cagttgtcag tggtcgggac ttgcacaaag tgcttgaaat
     1201 taaaacagct tataaagatt ggtttccaag aatggccgaa tatggctttg aagaaggtca
     1261 ggactttagc tcatttttga gcaaaagtac aggaggtcgc cctagtcaag accatgtact
     1321 taaactagac atggctaaag aaattgcgat gttgcaacgg aatgaaaaat caaagcaagt
     1381 ccgcaaatac tttattcagg tcgaaaagga ctttaatagt cccgagaaaa tcatggcaag
     1441 agccctgctg atggcagaca agaaagtaca taaattagag gctcagattg aggctgaccg
     1501 tccaaaggtg ctatttgctg atgctgtaag tgctagcaaa tcatcttgtc tgattggtga
     1561 gctagctaaa atcctgaaac agaatgggat caatattggt cagaataagc tatttcagtg
     1621 gttacgagcc aacggctacc taatcagtcg ccgcggtgag tcttggaatc agccaacgca
     1681 aaaaagtatg caacttggat tgtttgaact caaaaaaaca gccatcaatc actctgatgg
     1741 tcacactaca acaaatgtaa ccccaaaagt tactggtaag gggcaacaat actttattaa
     1801 taaattcctt aatcaggaat atctaccagt ttagaaacgt aacaaaacta acgaagggag
     1861 aaaatatgga agagaaaaaa ttttttacta catatgaaat ggatctgatg aattcagttg
     1921 taactcttca aaaatcaatc ttaacgcaaa cggaacattt gtcagatcaa ctaacaaaaa
     1981 agcttcatca cctagaagac tacaatagtc cgattgatga tgaagcaatt agattggctg
     2041 aggtaacagc agaattttac aagttgttaa tcaagtctcc tagtgttgga gcaactgtca
     2101 aggagattgt gagcgaggga cataagcgtt aaggccgtaa gagcgtcatt gagattatct
     2161 ggattgtagt atttgagttt gtgagcttta gagttgcgat aaaggtgagc gattgcaagt
     2221 agcaaatttt ttaatccctt atactcactt tgttcgtcta gagtctgcaa tttattaccg
     2281 ttgataatca caatgggttc tccgggtttg aaacattgat ctatcagact agctgagtcc
     2341 attgctgagc ccgttagtag acgaatacga tgaaaaacac ctttacttgc ttcaaatacg
     2401 gcatgaaaat agttttcttg taagagctct tgagtgcaga attttaaaac gtgagggtgt
     2461 acttttaatt cttttaacct actatcaagt gtttcgaagc gttttttggc ctctgataaa
     2521 gtttttgaag tagtagtagt aacaatttgt ccgctatctg atacaatcaa accttttagc
     2581 gagagcggaa tgttaatggc ggttcttaac tgttcaaaaa ttgaaacttc attaatgtat
     2641 cttaaaggat tacagacgta ttcaatcaca agttttatat tatctgtatt ctgtgtccta
     2701 tttaatatat cggacatgag attgtgcacc cgtttgtgct tgttaaatcc agaattttgg
     2761 tcgttttggg gataacctaa aacttcgccc attcgggtta tttcagaatg cgaaacatag
     2821 tcagatagta ttttaccgat tgtatcaacg aattgggtgt caatatttaa cataacaaac
     2881 ctcgttttta tttaaattat accacagaaa ggagaaccac atgagaccaa aacgatatcc
     2941 gtatagcgga gagaaaaaga gagcctatca taagatagac cctgaactga taaaaaccgg
     3001 taaagttgat tgcatcaatc tcccttaagt acgccaagct ctaacaatgc atttgtcata
     3061 gctgcgatag tagatttaga ggttgactta gagacatact ccaaaatatt aacgatatgc
     3121 tgagcttgct tttgtgtaat aggtgcattc atttgattaa gttccgcaac gacaaattca
     3181 actaattggt tgtcaacatt gaaattttgg ttgatatgtt ttgagacaac tttcataaat
     3241 tcttttgtat ccataattaa tctcctttct tgcttatttg actaaacaag attagaagaa
     3301 tagaggtctc tcgagagatc ttgttgaatc atacgaatat tatatcaaga ctatattgaa
     3361 aaatcaatat attgtatata aaaagttatc aacaactaca tgttgtgctt aggaggaatt
     3421 atgtggggta aaatcgaagc tctattaatt gagaaaaaaa tgaccaaata tgaactgtca
     3481 caaaaggctg gattgaacca aaattgcttg attgatctaa agaaaggaag aaaaaaatca
     3541 ttgaaatttg atgatgtcgt taaaatcgcc gatgtcttag gtgtcagctt ggacgaattc
     3601 agataacaaa aaaagtccga cggcaatcgg actcaaaact agattaattt acttaattat
     3661 accacaagag agaggatatt aatatgccaa aagcagaaat tacttataga gcagttgatg
     3721 ttaatgaaac agcttctcat ggtgattata aacacttgat tcaacaatgg gaggggttga
     3781 cagttgctac tgcaaagcag tgggcgacag aaatgcgtga tcatccagac tttaaacagt
     3841 ttgtattaaa tccaacgcat agaatcgtat tcattgatta cgaaggattc aaactgtttg
     3901 tacagtggaa atctcgcaat cgttataaaa caaaaaaaga gacactgtca gaaatgcttg
     3961 aaaatattaa attcgaaaaa agagtaggag cataacatga acaaattaga actattttta
     4021 ttagtaacaa cgatcatctt agcaatcatc actagagtac aacacgaagt cattaaaaaa
     4081 cataattcgc cagagaataa acgcagaatt tttagagaag tggctttaga aaacagcaaa
     4141 gggtggagag agaagcgttc tggaggaaag gtggtcagct gatgcagtac atttttcaaa
     4201 aatacgacaa gtagctatac atccgttagc aacgaattta tagatgattg tgaattatcc
     4261 ctaaaatcaa aaggcctgct tatggtaatt cttagaaata aagaagattg gagagtatat
     4321 ccagaggaat tggctagaag gtccagagat agcgtgagag ttgtaaggac ttgcttagaa
     4381 gaattagaga gagtcggata tgtgagaact tacagaaaat ctttagggcg agggaaaggc
     4441 atacaatatt atagattttg ctcagataaa aagatatccg aacaagcatt taaaaaaatg
     4501 attagtgatt ttacaactta acgttttaca aagttgtatt ttacaaagtt gtattttaca
     4561 aagttgtaaa acgtaacact aataattact aacttataaa taaatactaa ataacaataa
     4621 atactaacag ataataagat gatgctgcta gaagggagtc gataaatgac taaaaaagaa
     4681 ctttttgaaa attttcagaa gaattggatg aggcttcttt cgccgtttga aatagaggat
     4741 atcgataaat ggatagatga agacaatatg cctgtagaag ttgttaatga agcgttgaaa
     4801 gaaacagtta tatacaacgc accgaacctt agatacttaa acagagttct aaacaattgg
     4861 aagcggcaag ggattgatac agtcgagaaa gtcgaatttg ctagattgca atttgagaat
     4921 aaaaagctca gtcaaaataa aaatcaacaa tccaacgtcc ctagctggtc caatccagac
     4981 tacaaagaac cagatttaaa agaatttgct ctaggaagca tggacggtat agaagatgga
     5041 tcaggagatt tttaattttt ttaacaaaca aatcaaaaaa gattttggta aaacggcgag
     5101 taaagagact tttgctaagt ttgctagtta ctgcgccgaa ggaatcgaaa aaaatggagt
     5161 taagccaatt tttaattgga taaacctata cgcttttgga accggtatga caacagcaga
     5221 agcagaccga ttaagaatag agcgatataa acaggagaat gtgttatgac aaaacagcat
     5281 agagaaacgc ttatctggta cagagcaagc catcaagagc gtgagagatt gcttgatttc
     5341 gggcttgttg ataaatcaca gtacatgaca ctattgcggc aattgcgcaa gaaatatgcg
     5401 atttaggaga aaatatgaca ccagaacaag cagaaaaagc aaaaatcaga gctaaacaag
     5461 aacttgaaac gtttagcata taccttgatc aggcaattga tgagctcggt ggagttctaa
     5521 cttcacgaga agtcttttta gcagcgggaa taacatatct tggcgcaggt cagacagata
     5581 tacatgctgc agtcgaggga ttatgtgagc aaatccaatg attttaaatt tagtgaagac
     5641 tgggagagca actaaaacac aggaagagga aatgaaatga acatcaaaga aaaaattgta
     5701 gtgctaagaa acactgaaga cggaagtttt ttaaagagtt tcaaaaacaa aaaagatgta
     5761 cttgcttata atgtggaact tacagatagc attcaactgg catcattttt accagaagaa
     5821 gcttacaaca tacaaaaaga aaaaattgat aatttggcag aaacgcttgg gtgtgatgtt
     5881 gtagttatcg aagcatcata tgacctaaaa tttattgatg gcgaggatgt tccagagtta
     5941 acaaaagagc aaaaagttaa aagtatggta aacggaatgt ttgagcaggt ttttggaggt
     6001 gaatagagat ggcaaatcaa ttatcaacat acacacacaa acaatttttt aacgcaccaa
     6061 caattcaaaa agcttttgat gacgtttgga aaggcgccgg gacacagttc gcagtaagca
     6121 tcttgtcagt actacaaggt agtcaaagtt tgaaatcggc atctaatgaa tctatttatg
     6181 cagcagctat gaaagcagcc gtgttaaatc tgcctattga gccaagctta ggaagggcct
     6241 atttagttcc gtacaaaggt caagcacaat tccaattagg ctataaaggg ttgattgagt
     6301 tagctcagcg cagcggacaa tacaaaaata ttaatgcagg tatcgtctat aaatcacaat
     6361 taatttctta caaccctttg ttcgaggaat taatccttga ctttagcaag ccacaagatg
     6421 aaattgtagg gtattttgcc gcttttaaac ttttaaatgg attcgagaaa gtttcttttt
     6481 ggacagtaga aaaagtaact gcacatggaa agaaattttc aaaatcgttt gctagcggtc
     6541 cttggaaaac agactttgat gcaatggctc aaaaaactat tttaaaagat attttgagta
     6601 aatatggtcc gttatcagtt gagatgcaga aagctatcga ggaagataat caagattcaa
     6661 cgatttctac cccaaaagac attaccccac aagaagcaaa tagccttgac gacctaattg
     6721 gtcaccagaa cgaaaataag gatgctccta acaatttaaa agacgtaact gaagatttac
     6781 atgacgaaga agaaaaaacg ctcgcagacg aaaataagac ggctttagaa gatacgtctt
     6841 atccggctga tgaaatccct gatttcgacc aagagacagg cgaaattaaa gctagcgaag
     6901 gcaacctctt tgataacctt ggggacttaa tgccatgacg aagttagact tgctcggaaa
     6961 ggactattat agccgtgaat cagcgattaa atactggtcc attagtcagt acaagcgttt
     7021 tagagagtgc gaggcaaggg cgcttgctga attacgaggg ggttggacag ataccagaga
     7081 taacactgcg ctgctcgtcg ggaactatgt ccactcttac tttgagagta aagcagctca
     7141 tgaagaattc aaagcccaaa acgactctga aatgatttcg accagaggaa caactaaagg
     7201 tcagctcaaa aaagactatt tagtcgcaga acagatgatt gaagcactta aaaatgacag
     7261 taacttcatg gccatatacc aaggagaaaa agaagcagca atcacaggat ttcttggcga
     7321 ggttgaattc aagggtaaaa tcgactgctt gaatgttgaa cgtggctatt ttgtagacat
     7381 caaaacaaca aaagggccga ttgacgacac aatctggaat agagaagagc gtgtcagatg
     7441 gtttgaagct tatggatata ttttgcagat ggctgcttac aaaaccatgc tagaagctaa
     7501 atacaataag ccgtttaagc cgattattta tgcagtgact aaagaaacgc cgccagacac
     7561 gagagccatc agaatccaaa atgtagatgc tatgcaaaat gagttagacg atttagccca
     7621 aaacatcaag catttagatg atgttaaaaa aggcctagaa aaacctaagc cttgcggtca
     7681 ttgcgagtat tgtagagcca atcaattaac acaaagagta atgatttttt aggagataga
     7741 aatgactaaa tactatgtat cagctaagat tgcaaattta gacattggtg cagaaactga
     7801 agcagaaaat caacacatgg ctccgatagc gtttaaagaa acgtacgacc atttacttag
     7861 atttggaagc cataagctga taatattagg cgtcgaagaa ctcaattaac aacctattgc
     7921 aaagtgaagc tcgacctttg cagtatcaat attttccgag tgagaaagga aagttggaat
     7981 atcgtcaagt taacaggatc gatgatatga agaattgcta cactcgtcct tgccaatgct
     8041 cacacacaat tttagggcga gtgtggattt taaaaaggtg aaaaatatgg aacaaatcaa
     8101 aattacagga acaggaacag cactaatttt agatagagta aaccgaatct ttgccatctc
     8161 tggcagtttg actatgcaat gggattttat tagtggtttt aaaaagattg acgacgaacc
     8221 gtcacttgat gaagatggag agttattcga aacagcctac gacctcattc ttgcagctaa
     8281 acccaaaact aaaatcaatc taacatcttc atactttgct aaagagcaca agaaagacat
     8341 agacgaaatc ataaaagtat tctcatttat cgaagataac aagagaaata tctttgaaac
     8401 ccttggcatt cgcggggtgc ttgaatgagc aatctagttt tatcgttaga catctcaaca
     8461 tctggaacag ggtgggcctt atttaaaggc tcagatctta tccagagtgg tgtcttaaaa
     8521 cataagagta aatcctactt tgagcgcggc cgctatatgg ctagtcaatt aaggctaatc
     8581 cagtcacgag cattaaaaaa atacgattgc tattttagta caatcgcagt cgaaaaaaac
     8641 tcggttatgg gacctaacca gcaatccatg cttaaaatcg gtattgttac aggaattatc
     8701 ttaggaagat taatagctga taacgtcgtg tttatcaatg tatcaacgtg gcgtaagtat
     8761 tggaagttta gctacaaaga ccgaagcaag aagtccatga aattacagtc aaaaataaaa
     8821 gtggagcaag aatttaataa atcggtcaaa gacgacgaag cagacgctat tttgattggc
     8881 tcatactatg tcaatcaagg ctatcttgat gaattggaga cacatgacta ctactaaaaa
     8941 cgaagcgatg cggtttatta gacagctaga gttagctagc ggcaagcgcg taaacgagta
     9001 ctacatgaag gggtaaacgg atgactgaag aacagatgat tgattgcttg ctttatgagt
     9061 tagtaaaaaa agacaaagca atcaaaaaga aaagcatcat tatcgctgca ctaacagtta
     9121 tgctgattgt cgtatcaggg ctttgcgtat cgcttaaaag ctattatgaa ccgcaaatat
     9181 acggactacg tacacagcta agcaggacac aaaagcagct taaacgtgcg agtgagcaaa
     9241 atcagagaca gacaaagcgg attgctgatt taacgaa
//
LOCUS       DAUGQX010000053         8932 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUGQX010000053 DAUGQX010000000
VERSION     DAUGQX010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8932
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.053"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            90..1010
                     /gene="lmb"
                     /locus_tag="VIA51_001535"
     CDS             90..1010
                     /gene="lmb"
                     /locus_tag="VIA51_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEQ8683473.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1023..3500
                     /locus_tag="VIA51_001536"
     CDS             1023..3500
                     /locus_tag="VIA51_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEQ8683474.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTP
                     NPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEED
                     GLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDDDSGSDH
                     SKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHF
                     HYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGK
                     VGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSS
                     LPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDIWSKPG
                     HEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKE
                     TFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQ
                     ADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIF
                     QPEGVQFYNKNGELVTYDIKTLQQINP"
     gene            3669..3869
                     /locus_tag="VIA51_001537"
     CDS             3669..3869
                     /locus_tag="VIA51_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8683475.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(3950..4576)
                     /locus_tag="VIA51_001538"
     CDS             complement(3950..4576)
                     /locus_tag="VIA51_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683476.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4560..5363)
                     /locus_tag="VIA51_001539"
     CDS             complement(4560..5363)
                     /locus_tag="VIA51_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683477.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5375..6196)
                     /locus_tag="VIA51_001540"
     CDS             complement(5375..6196)
                     /locus_tag="VIA51_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683478.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6193..7170)
                     /locus_tag="VIA51_001541"
     CDS             complement(6193..7170)
                     /locus_tag="VIA51_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8683479.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            complement(7283..8911)
                     /locus_tag="VIA51_001542"
     CDS             complement(7283..8911)
                     /locus_tag="VIA51_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8683480.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         2920 a         1761 c         1776 g         2475 t
ORIGIN      
        1 aaaagatggt agttgccatt gacaaagcat tgataaagga gtaaaattaa ctggttaata
       61 actggttaaa ttataattga ggaggtacta tgaaaaaagg tttttttctc atggctatgg
      121 tcgtgagttt agtaatgata gcagggtgtg ataagtcagc aaaccccaaa cagcctacgc
      181 aaggcatgtc agttgtaacc agcttttacc caatgtatgc gatgacaaaa gaagtatctg
      241 gagacctcaa tgatgtgagg atgatccaat caggtgcagg cattcattcc tttgaaccgt
      301 ctgtaaatga tgtggcagct atttatgacg cggatttgtt tgtttaccat tcacatacct
      361 tagaagcttg ggcaagggat ctagacccta atttaaaaaa atcaaaggtt gatgtgtttg
      421 aagcgtcaaa acctttgaca ctagatagag tcaaagggct agaagatatg gaagtcacac
      481 aaggcattga tcctgcgaca ctttatgacc cacatacctg gacagatccc gttttagctg
      541 gtgaggaagc tgttaatatc gctaaagagc taggacgttt ggatcctaaa cacaaagaca
      601 gttacactaa aaatgctaag gctttcaaaa aagaagcaga gcaactaact gaagaataca
      661 ctcaaaaatt taaaaaggtg cgctcaaaaa cattcgtgac gcagcacacg gcattttctt
      721 atctggctaa acgattcggc ttgaaacaac ttggtatctc gggcatttcc ccagagcaag
      781 agccctctcc tcgccaattg aaagaaattc aagactttgt taaagaatac aacgtcaaga
      841 ctatttttgc agaagacaat gtcaatccca aaattgctca tgctattgcg aaatcaacag
      901 gagctaaagt aaagacatta agtccacttg aagctgctcc aagcggaaac aagacatatc
      961 tagaaaatct tagagcaaat ttggaagtgc tctatcaaca gttgaagtaa aggagattat
     1021 tagtgaagaa aacatatggt tatatcggct cagttgctgc tattttacta gctactcata
     1081 ttggaagtta ccaacttggt aagcatcata tgggttcagc aacaaaggac aatcaaattg
     1141 cctatattga tgatagcaaa ggtaaggcaa aagcccctaa aacaaacaaa acgatggatc
     1201 aaatcagtgc tgaagaaggc atctctgctg aacagatcgt agtcaaaatt actgaccaag
     1261 gctatgtgac ctcacatggt gaccattatc atttttacaa tgggaaagtt ccttatgatg
     1321 cgattattag tgaagagttg ttgatgacgg atcctaatta ccgttttaaa caatcagacg
     1381 ttatcaatga aatcttagac ggttacgtta ttaaagtcaa tggcaactat tatgtttacc
     1441 tcaagccagg tagcaagcgc aaaaacattc gaaccaaaca acaaattgct gagcaagtag
     1501 ccaaaggaac taaagaagct aaagaaaaag gtttagctca agtggcccat ctcagtaaag
     1561 aagaagttgc ggcagtcaat gaagcaaaaa gacaaggacg ctatactaca gacgatggct
     1621 atatttttag tccgacagat atcattgatg atttaggaga tgcttattta gtacctcatg
     1681 gtaatcacta tcattatatt cctaaaaagg atttgtctcc aagtgagcta gctgctgcac
     1741 aagcctactg gagtcaaaaa caaggtcgag gtgctagacc gtctgattac cgcccgacac
     1801 cagccccagc cccaggtcgt aggaaagccc caattcctga tgtgacgcct aaccctggac
     1861 aaggtcatca gccagataac ggtggctatc atccagcgcc tcctaggcca aatgatgcgt
     1921 cacaaaacaa acaccaaaga gatgagttta aaggaaaaac ctttaaggaa cttttagatc
     1981 aactacaccg tcttgatttg aaataccgtc atgtggaaga agatgggttg atttttgaac
     2041 cgactcaagt gatcaaatca aacgcttttg ggtatgtggt gcctcatgga gatcattatc
     2101 atattatccc aagaagtcag ttatcacctc ttgaaatgga attagcagat cgatacttag
     2161 ccggccaaac tgaggacgat gactcaggtt cagatcactc aaaaccatca gataaagaag
     2221 tgacacatac ctttcttggt catcgcatca aagcttacgg aaaaggctta gatggtaaac
     2281 catatgatac gagtgatgct tatgttttta gtaaagaatc cattcattca gtggataaat
     2341 caggagttac agctaaacac ggagatcatt tccactatat aggatttgga gaacttgaac
     2401 aatatgagtt ggatgaggtc gctaactggg tgaaagcaaa aggtcaagct gatgagcttg
     2461 ctgctgcttt ggatcaggaa caaggcaaag aaaaaccact ctttgacact aaaaaagtga
     2521 gtcgcaaagt aacaaaagat ggtaaagtgg gctatatgat gccaaaagat ggcaaggact
     2581 atttctatgc tcgtgatcaa cttgatttga ctcagattgc ctttgccgaa caagaactaa
     2641 tgcttaaaga taagaaacat taccgttatg acattgttga cacaggtatt gagccacgac
     2701 ttgctgtaga tgtgtcaagt ctgccgatgc atgctggtaa tgctacttac gatactggaa
     2761 gttcgtttgt tatccctcat attgatcata tccatgtcgt tccgtattca tggttgacgc
     2821 gcgatcagat tgcaacaatc aagtatgtga tgcaacaccc cgaagttcgt ccggatatat
     2881 ggtctaagcc agggcatgaa gagtcaggtt cggtcattcc aaatgttacg cctcttgata
     2941 aacgtgctgg tatgccaaac tggcaaatta tccattctgc tgaagaagtt caaaaagccc
     3001 tagcagaagg tcgttttgca acaccagacg gctatatttt cgatccacga gatgttttgg
     3061 ccaaagaaac ttttgtatgg aaagatggct cctttagcat cccaagagca gatggcagtt
     3121 cattgagaac cattaataaa tctgatctat cccaagctga gtggcaacaa gctcaagagt
     3181 tattggcaaa gaaaaacgct ggtgatgcta ctgatacgga taaacccaaa gaaaagcaac
     3241 aggcagataa gagcaatgaa aaccaacagc caagtgaagc cagtaaagaa gaagaaaaag
     3301 aatcagatga ctttatagac agtttaccag actatggtct agatagagca accctagaag
     3361 atcatatcaa tcaattagca caaaaagcta atatcgatcc taagtatctc attttccaac
     3421 cagaaggtgt ccaattttat aataaaaatg gtgaattggt aacttatgat atcaagacac
     3481 ttcaacaaat aaacccttaa ccaaaagaag atctcattgt taaagcactg ctttgtcaaa
     3541 gcaagttacg gtgattttga agtcatttta tgtaacgagt agtgataaaa gttggataat
     3601 agcggttttc ttttgcaaag aaatggtatc catgttagaa tgataaaaaa aagaggagga
     3661 ttctaatcat gtcagaagaa aaattaaaat caaaaattga gcaagcatct ggtggcctaa
     3721 aagaaggtgc tggtaagttg acaggtgata aagagctaga agcaaaagga tttgttgaaa
     3781 aaacaattgc taaaggcaaa gaacttgcag acgatgcaaa ggaagcggtt gaaggtgctg
     3841 tagatgccgt taaggaaaaa ttaaaataat taaaaaacca gctgtaagct ggttttttta
     3901 atggtgtgat tttgttagga aaagactcaa taggtaataa ccgtaggtgt taggtatgct
     3961 tgaacagttg agtacgattc tcttcaatca tatagcacgc gtcacaaagt ttttctaaca
     4021 tatcaaactc atgactaata atgatgagac ctaaatttct atcctttaca atctccaaca
     4081 ggcttttcca tacactagct tgtgtaatgc tatccaacat agtagtcatt tcatctgcaa
     4141 taaggtattt cgtctctgga tgtaatgaac gcacaatcga aaagcgttgc aattcccctc
     4201 ccgagagttc actaggacga cgctttagcc atttttcttg aatgccaaaa gcatctcgca
     4261 aatcttgact tggatagtag gcttcttcca aacttttttt cataggccat aaaggattca
     4321 tggtttgttc aggatgttgt tggataagtt gtacaggtct aaatgctttg ttaggcaaat
     4381 gactgccatc aactaatact tcaccagatt taggctgcaa aaaaccagca agcactctgg
     4441 ataaactcgt ttttccacac ccactttgtc caaatatccc taagatttga ccaggtgcta
     4501 cctctaaatc aatctcctta aaaagccatt gatctttttt atgataaaag ccaagctttt
     4561 tagcctctaa ggtcatgagt aactcctttc aaaaagtctt gctgagggag tgtgcgccat
     4621 aaacgtctcg caaattctgt ttgtaattgc tccccacctc cgctaaaaaa gctagctggg
     4681 gctgtttcaa tagcttttcc ctctttaaaa atagtaatac gatccgcaat ttgactagct
     4741 gctacaatat catgggtgat aaatatgacg cttattcctt tatctgcaaa ggagcgtagt
     4801 tgatctaaaa ccatttgcag agcatctgga tgtaatccag gggtgggctc atccgcaata
     4861 atcaaagaaa ccgtatcact aatacacgtt gtaaacaaaa cacgtcggag cattccgcca
     4921 gaaagttgga aaggatacaa gtcaccatca ctttctttta atccaaactg ttgaaacaat
     4981 ccttcttgag tagccttagc attttctgag atacccaagc gcacctgatg cttgactttc
     5041 atagatggat ctaaataatt aacggattgt ggaatcaacg tcatttcttt tcctcgcaac
     5101 tgtttgatgc gtttagaagt tagtgattga ccacgataaa tcatatctcc tgttacagct
     5161 gcatttttag gaagaatatc cataatagca tgtgctaata aactcttgcc tgaaccacta
     5221 gcacctataa tagctaataa ctcacctttt ttaacttcta aattcagcgc ttggatcggt
     5281 gtggattgaa atggttttaa aaatcttccg tattgagtga aggtgatgga gaggtcttta
     5341 atgcttaata atgtttctgt catatctcta cctcctaaaa atgatccgtt tgagggtaaa
     5401 agagtttctt taaagattct ccgatagtat caaaggcatt gacaaccaaa ataagataaa
     5461 ggcctggaaa aatcaccaac caccaattgc caagagagat atgcttagct gcctctgaca
     5521 aaatgatacc aaccgaaggt tgttcggcag aaaggccaaa tcctaagaaa gtcatggatg
     5581 cttcatgcaa gatgacgtgc ggaaataaga ggataaaccc aatgaaaatt tgagaagcaa
     5641 tcaaaggcag gatatgatgc ctcacaatat aataaggcgt ttttcccatg cttttagaga
     5701 gctggacaaa ggctttattc tttagatcat agacttcatt gcggataagc cttgctagag
     5761 agggccaatg ggtaacagct gttgcaatga taaccccttg agcccctttc ccaacaacaa
     5821 aagaaatgag aatcataaaa atcaaatgag gcataccaat aaacaaatca accaaccagg
     5881 ctattatttt atcaataagg ctatttccta gacctgcaag cactccaaaa acggtcgcaa
     5941 gaaagactcc cataagggcg cctaataagc cgacttgtaa agagaaataa agccctttaa
     6001 tcgttctgac aaacatatcc ctacctaaac catctgtccc aaaaagatgg tttaaggaag
     6061 gagcgaggtt gcgtaaagct gcattggttt ccaaaggcgt cctatagaaa taaaggttta
     6121 aggctagaat actaagaatg agagaaatgg cgatacccag ttgccataaa accatcgttc
     6181 gacgtttcaa tatcatactt ttctccttaa ctgtggattg atgatgctat ttaaaatatc
     6241 cgcaataaga ttgcccgcaa aaacaaataa tgtccctatc atcacaatag ctagaaggag
     6301 cggtgtatca cttttaagtc ctgcttcagt gagggtagac cctaagccag gatatgagaa
     6361 aacttgctca gcaagaacag atcctccaaa caattctcca aaataggaaa aatgcagtgt
     6421 aatagctggt acgatagcat ttctaaggca atgatgttta aaaatttgcc actgtgtttc
     6481 cccacgcgct ctggcaaata agacatattc actagaaagc accgacatca ttttagttct
     6541 cgtatgaagg gtgacattgg caatgcctag aatacttagc gtgaaaacag gtaacataag
     6601 gtgcttaact cgatcagcta acgtaatatc ttgactcaaa gtgcctatcg gggaagaaat
     6661 accaatcggg aaccacccca gctggacaga aaagattaat aaaaaaatga gtccaatcca
     6721 aaacgttggt actgatatct gaaggtatga aaaccacctg acaactcggt caagtaattt
     6781 cccttgatgg aaagcggata acgttcctaa gataaatcca ataagacccg ataagatcca
     6841 agagagtccc ataagtatga aagaagcacc tgcccgtgat ctaataatat cactaacagg
     6901 ttgccgataa acgagcgagg tccctaaatc tccctgtatc acatttttca accaaataaa
     6961 atattggact agagctggct tatccaagcc atagtggtga gcaatcgctt tgtactgagc
     7021 aggggttagt gatgtgtcat aattgacact tgccatgact ggatctactg gagattgttt
     7081 taacaaaacg aaggtcaaaa cagatacccc aaaaataagc gtgacacatc tgatgatttt
     7141 ccagatgata ataatggtag tacgtttcac aatgaaatct ccttaatcga taagaaaagg
     7201 agccgaggaa acgatcagca cagttttgtg tatcttgttt tctcagactc caaacttaaa
     7261 gtcgctgtat taactaaacg cgttacttag ttgattcatc ccaagtccac tcggcaatgt
     7321 tagtcaataa tgaccaatca tgaccatgac tgtggacgcc ttgtttacct acattgatac
     7381 gtttatcacc aatataagta tggttaaggc tcaccaacca tacatttggc aaatctccaa
     7441 gagtagaagc acctgttttg ccatcccact gcgctaactt ccaatattcg ttagctttgt
     7501 caaggtcaga agatgtcatt gctttgtcaa ggtacttagt cacggtagga ttgttataaa
     7561 acgtaatatt ggtccaacct ttccctgcta ggcttggatg atgcgattca taaaattgct
     7621 gcgcgtgatg acgtcctccg gcataaagta aggctgagtc atgtgacttc gttgccattt
     7681 catcccagtt actagctttg agtttaatag taatccctag ggccttggct tgctctgcta
     7741 cttcaacggc taagttcgct cgcaattgat cattagtagg gtagtacaga tcaaacgctg
     7801 catcaaggtc acctttttta cggctaccgt ctgcttgttc tttccatccc gcttttgtca
     7861 ataattgctt agctttagct actttattat ctttaatggc tgtttttgga ttccaaaatg
     7921 gtgttttatc aataattgaa taagctggtt taccataacc atttaaaacc gtatcgagaa
     7981 ctttttgcct atttaaacca atagtcaagg cttttcggat tgctggatca ctagtgacat
     8041 catttcctac aggataacca tcaggagaat cagtgatgac gccctttttc acataaggta
     8101 atgataagcc gcgcacatca tttgatggaa tatcaaggag gcgggtgcct ttgacttttt
     8161 tatcagcaag ttctggcgtt gcgtagatca tatcaacatc accagattct aaagctgcta
     8221 gtgctgtgtt ttcatcaagt aagacccaag tccatttttt aaagtatggt tttttcccat
     8281 gccaataagg gttacgaaca aaaatagctt gttctccagc cttatattct tttaccatgt
     8341 aaggtcctga accgatagga ttgctcttat acttatcatt gtaatgtttt ttagggacga
     8401 ttgggatttc agtcaactgt gctgtaaatg tcgaatgcgc ctcagtcaaa tggatattga
     8461 cctgattttt cccaactact tcaacgttct taatgaaggt tagatcccaa gcctttccat
     8521 ctgctttcaa catatcataa gtaaacttaa catcatcagc agtaacaggc tcaccatttg
     8581 agaatttaaa atcatcatgc aagtcaaacg accaagtcag cccatcttca gagagatggt
     8641 atgttttagc aagctctcct tttatatcta gttcaggaga acgtttcaat agagtgctat
     8701 gagtgatatt cccttcattg tggactccat aacggtcctt tggatcgaat tcatgaggga
     8761 gctttgcccc catagaaacg acaagttcgt cttttggacg ttgtttgcgc tgacgttctt
     8821 ttgtttgagg cttttgttgt tgacatgcaa ctaaaataag cccagtcaaa aataacgtga
     8881 taatagagaa gtattttagg tattttgaca caatcaaatc tccttatttc ta
//
LOCUS       DAUGQX010000054         8768 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUGQX010000054 DAUGQX010000000
VERSION     DAUGQX010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8768
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.054"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            44..910
                     /locus_tag="VIA51_001543"
     CDS             44..910
                     /locus_tag="VIA51_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEQ8683481.1"
                     /translation="MKMKKKFFLLSLLALSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     YQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            921..1856
                     /gene="pstC"
                     /locus_tag="VIA51_001544"
     CDS             921..1856
                     /gene="pstC"
                     /locus_tag="VIA51_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEQ8683482.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1846..2733
                     /gene="pstA"
                     /locus_tag="VIA51_001545"
     CDS             1846..2733
                     /gene="pstA"
                     /locus_tag="VIA51_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEQ8683483.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSAHFIGKKLHSKMTAAK"
     gene            2749..3552
                     /gene="pstB"
                     /locus_tag="VIA51_001546"
     CDS             2749..3552
                     /gene="pstB"
                     /locus_tag="VIA51_001546"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683484.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            3565..4323
                     /gene="pstB"
                     /locus_tag="VIA51_001547"
     CDS             3565..4323
                     /gene="pstB"
                     /locus_tag="VIA51_001547"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683485.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            4391..5044
                     /gene="phoU"
                     /locus_tag="VIA51_001548"
     CDS             4391..5044
                     /gene="phoU"
                     /locus_tag="VIA51_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEQ8683486.1"
                     /translation="MLRMKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5249..7786
                     /locus_tag="VIA51_001549"
     CDS             5249..7786
                     /locus_tag="VIA51_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEQ8683487.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTLRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQPTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            8132..>8768
                     /locus_tag="VIA51_001550"
     CDS             8132..>8768
                     /locus_tag="VIA51_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8683488.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTCFVNRLQT"
BASE COUNT         2699 a         1477 c         1797 g         2795 t
ORIGIN      
        1 ttctacatat atacccttta tttttacgaa taggaaataa ataatgaaaa tgaaaaaaaa
       61 attctttttg ttaagtcttt tggccctatc aactttcttt ttatccgcat gttctagctg
      121 gattgataaa ggtgagtcaa taaccgctgt aggatcaaca gcactacaac ccttagtaga
      181 agcagtagct gatgaatttg gaagcagtaa tctaggcaag actgtcaatg ttcaaggtgg
      241 tggttcaggt acagggttgt ctcaagttca atcaggagct gtccaaattg gaaatagtga
      301 tgtctttgcg gaagaaaaag atggtattga tgcttctaaa ttagttgatt atcaagtagc
      361 tgttgcagga cttgcagtta ttgccaatcc taaagtcaag gtttccaatc tcagtagtca
      421 gcagttgcaa aagatttttt caggagaata taccaattgg aaacaagttg gaggagaaga
      481 tcttgcgatt tcagtgatca accgagcagc aagttctggc tcacgagcaa cctttgacag
      541 tgttatcatg aaaggggtca acgctaaaca aagtcaagag caagactcca atgggatggt
      601 taaatcgatt gtttcacaaa caccaggtgc catttcttac ctttcctttg cctacgttga
      661 ttcatctgtt aaatctttgc aattaaatgg gtttaaggca aatgctaaga acgtggctac
      721 aaatgattgg ccaatctggt cctacgaaca catgtatacc aaagataaac caacagggtt
      781 gaccaaggaa tttcttgatt atatgttttc agatgaagta caacagaaca ttgttacaca
      841 tatgggatat atttcgataa atgatatgga agtggtcaaa tctcatgatg gaaaagtaac
      901 aaaaaggtaa tggaggaatt atggaaaatc aggaattggc taaaaaatta gcctcaccat
      961 caaagaattc aaggcttgaa acctttggcc gcaccattac gtttttgtgt ctggctttga
     1021 ttgtttttat cgttgcgatg attctgatct tcgttgctca aaaagggttg tcaaccttct
     1081 ttgttgacaa ggttaatctt tttgatttct tgtttggaaa ggagtggcaa ccaagtgtaa
     1141 aaaatgcggc cggcattcct tatcttggtg ctctgccaat gattacagga tcctttttgg
     1201 ttaccatttt atctgctatt attgccaccc catttgccat tggcgcagcc gtttttatga
     1261 ctgaaatctc acctaaatat ggcgctaaat tattacagcc tgcggttgag cttttggttg
     1321 gaattccttc ggttgtttat gggtttatcg gtttgcaagt gattgttcct tttatgcgct
     1381 ctatctttgg tggcacaggt tttggaatcc tatctggggt ctgtgtcttg tttgttatga
     1441 ttttaccaac agtgactttt atgacaacag acagtctgcg ggcggtgcct cgtcattacc
     1501 gcgaagcgtc tatggctatg ggagcaacac gttggcaaac catttggcgt gttgtcctta
     1561 atgcagctcg tccaggaatt tttaccgctg ttatttttgg aatggcaaga gcttttggag
     1621 aagccttggc tatccaaatg gtagtcggta actctgctgt aatgccaagt tcactaacga
     1681 caccagccgc aaccttaacg tctgtcttga caatgggtat tggtaacacg gttatgggaa
     1741 cggtccaaaa taatgtgctt tggtcccttg ccctagtctt attattaatg agtctggcct
     1801 tcaattccct tgtcaaatta atcacgaaag aaagaaagag aaattatgaa cgctaaaaaa
     1861 gtcgataaag tagcaactgg tactctttat accattgctg gaattattgt agctatttta
     1921 gcttccttaa ttctatatat ccttgtccgt ggcttgccac acatcagctg gtccttttta
     1981 acaggaaaat cgtcttcgta cgaagctggt gggggaattg gtatccagtt gtataattcc
     2041 ttcttcctat tgattgttac tttaattatt tccattcctt tatcaactgg agcggggatt
     2101 tacttggctg aatatgccaa aaaaggacct gttaccaact ttattagaac ctgtattgag
     2161 attctgtctt ccctaccatc tgtggttgtg gggctctttg gttacttgat tttcgttgtg
     2221 cagtttgaat atggcttttc tattatttca ggggctcttg ctttgacggt ctttaatctt
     2281 cctcaaatga cccgtaatgt tgaagatagt ttactgcatg ttcatcatac ccaaagagaa
     2341 gcaggattag ctttaggcct gtcacgctgg gaaacggttt tttatgtggt tatcccagaa
     2401 gctctcccgg gaatggtaac aggtattgtc ttagcttcag gtcgtatttt tggtgaagcg
     2461 gcagcgctta tctatactgc tggtcaatca gcaccagctc tggattggtc aaattggaat
     2521 ccacttagtg ttactagtcc aatctctatt ttccgtcaat ctgagaccct tgctgttcat
     2581 atttggaaag tcaatagcga agggacaatt ccagatgcta ctcttgtatc cgcaggaagt
     2641 gcagcagtgc tattaatttt tatccttatt ttcaactttt cagctcactt tattgggaag
     2701 aaacttcatt ctaaaatgac agcagcgaaa taagatattg gagaaatcat gacagaatac
     2761 aattggaatg aacgtcatat catcactttt cctgaagaaa cgcttgctct agctaccaag
     2821 gatttacatg tttactatgg tgcgaaagaa gctatcaaag ggattgatat gcagtttgaa
     2881 aaacataaaa taacagcctt gattggtcca tctggttgtg gcaaatcaac ttatcttcgt
     2941 agtcttaacc gcatgaacga taccattgat attgctcggg ttacaggtga gattctttat
     3001 cagggcattg atgttaatcg aaaagacatg aatgtttacg agattcgcaa gcacttagga
     3061 atggtttttc aaagacccaa tcctttcgct aaatccattt ataaaaacat tacctttgcc
     3121 catgaaagag ctggtgtgaa agacaaaaaa gttttagatg aaattgttga gacttcactg
     3181 aaacaagccg cgctttggga tcaagttaaa gatgaccttc acaaatcagc cttcacctta
     3241 tcagggggtc agcaacaacg cttgtgtatt gctagagcca tttctgtcaa acctgatatt
     3301 ctattaatgg atgaaccagc ctctgccctt gacccgattg caacgatgca gctggaagaa
     3361 accatgtttg aattgaagaa gaattacacg attattattg tgacccacaa tatgcaacaa
     3421 gcagctcgtg ccagtgatta cactgccttc ttctatttag gcaacctcat tgaatatgat
     3481 aagacacgta atattttcca aaatgcgcaa tgtcagtcaa caaacgacta cgtttcaggg
     3541 cactttggtt agaaaggtaa tatgatgaca gaacctattt tacagatcag agacctttct
     3601 gtttactaca atcaaaagaa aacgttaaaa gatgtctctt tggaccttta tccaaatgaa
     3661 ataacagctt taattggtcc ttctggatct gggaaatcaa cgctcttgcg ttctatcaac
     3721 cgtatgaatg atttgaatcc tgaagtaacc attacaggct ctatcgtcta taacggacac
     3781 aatatttata gtccaaggac agatacggtt gatttacgca aagaaattgg tatggtattc
     3841 caacaaccca acccatttcc gatgtctatt tatgagaacg tggtttacgg ccttcgctta
     3901 aaaggtatca gagataaatc aatcttagac catgctgttg aaagctctct taaaggggct
     3961 tccatttgga atgaagtcaa agatcgttta catgattctg cggttggctt atcaggcgga
     4021 cagcaacaga gagtttgcat agctagagtt cttgctacca gccccagaat aatcctttta
     4081 gatgaaccta cctcagctct tgatcctatc tcagctggga aaattgaaga aacattattg
     4141 ttattaaaaa aagattatac actggctatt gtgacccgct caatgcagca agcctcacgt
     4201 ttatcagatc gaacaggttt tttcttggag ggtgacttac ttgagtgtgg tcctacaaaa
     4261 gccatgttta tgaatcctaa gcgcaaagaa accgaagact atatttctgg taaatttggt
     4321 tgagaaagat gtatatggtt gacccctctg tgtttttatt ataatgacta gattgtagga
     4381 agaaaaaatc atgttaagaa tgaaatttga agaagaatta gataaattgc ataaccagtt
     4441 ttattcaatg ggaacggaag tattggcaca aatcaataaa actgttcgtg cctttgttag
     4501 tcatgatcgt gaattggcca aagaagttat cgaagaagat gacactatta ataattttga
     4561 gacaaagctt gaaaagaaat cgctggaaat tattgcccta caacagccag tttcgaatga
     4621 tcttagaatg gttattactg ttttaaaggc atcaagtgat attgaacgta tgggtgacca
     4681 tgctgcttcg attgccaagg ccactattcg tatgaaaggt gaggagcgta ttccagtggt
     4741 tgaagaacaa atcaacctta tgggaaaagc tgtgaaacag atggtagaag aagcccttaa
     4801 tgcatatatc aatgctgacg atacaaaagc ttatgaaatc gcagcttctg atgagattat
     4861 cgatcaatat ttccgtaata tccaaacctt agctgttgaa gaaatccgta agtctccaga
     4921 tgctgttttt gcaggaaaag aatattttca agtattaatg tatttggaac gtattggtga
     4981 ctatgctcgc aacatttgtg aatggattgt ttatcttaaa actggaaaaa ttattgaatt
     5041 ataagaaatt atgctataat gagactggga aacagcttgc cagtccctgg ttttatacga
     5101 aattgtgcaa gttagaaaat gaactaacaa gaaaagtttt ctttgctgaa tctgattttg
     5161 ttaggttaac aaatatatgt agacagagat gatacttagg tatcatctgt tgatctatta
     5221 tgatttgtta ttagaattaa ggagttatat gaagacagta gaacatctca tcgaaacatt
     5281 tgtgcctgaa aattataaca tctttttaga tattaatcgt cagactaaaa catttacggg
     5341 gaatgttgcg attaatggtg aagctttaga taatcatgtg gctttccacc aaaaagattt
     5401 ggacattaag tctattttgc tcgataatga agctgttatt tatcaagtgg ataacgacaa
     5461 tgaagttgtg cgtgttgaat tacctgaaac aggaatgatg acgcttgtca ttgaattttc
     5521 aggtagcatt acagataata tgacaggtat ttacccttca tattacacta aaaatggtga
     5581 gaaaaaagaa gtcatttcaa ctcagtttga aagccatttt gcacgtgaag ctttcccatg
     5641 tatcgatgaa ccacaagcaa aagctacttt tgatttaagc ttgacctttg atcaagaaat
     5701 tggtgagata gcgttatcga atatgccaga agtcaatatt gaccgtcgcg aggagactgg
     5761 tctttggaca tttgatacga cactaagaat gtcatcttac ttgctagcgt ttgcgctagg
     5821 agaacttcat ggaaagactg tagaaagcaa aaaaggaaca actgttggtg tgtatgcgac
     5881 aacagcgcat cctcttagct cgcttgattt ttcattggat attgcagttc gtgttatcaa
     5941 cttttatgaa gactattttg gagtacatta cccaatcccg caatctctta atattgcgct
     6001 tccagatttt tcatctggtg ctatggaaaa ttggggttta atcacttatc gtgaaattta
     6061 tttattagta gatgaaaatt cgactgttca aagccgacaa caagttgcac ttgtaatcgc
     6121 ccacgagata gcacaccaat ggtttggaaa cttggttaca atgaaatggt gggacgatct
     6181 gtggttaaat gagagttttg ccaacatgat ggaatatgtc tctatcgagg ctattgagcc
     6241 gtcttggaaa ataatagaag atttccaaac aggcggtatt cctcttgctt taaaacgtga
     6301 tgctactgat ggtgttcaat cagtgcatgt tgaagtcaat catccagatg agataaatac
     6361 attgtttgat cctgctattg tctatgcaaa aggtagtcgt ttgatgcata tgttacgccg
     6421 ttttattggt gatcgtgatt ttgccattgg cttacatcac tactttgaaa aatatcaata
     6481 tcgaaatact gtcgggcgtg atttatggaa tattttatca gatacttcag gcaaagacgt
     6541 agctgctttt atggatgctt ggcttgaaca accaggttat ccagttttaa cagctcgcct
     6601 tgaaaacgat caattgattt tgagtcaaaa acaatttttt attggaaaag gtgaagaaaa
     6661 aggtcgcctt tggccgattc ctttaaacac taattggcat ggccttcctg aaactttgac
     6721 agaggcagaa atggtcattc caaactttag tcaattggca gcagaaaatg aaggagctct
     6781 acgtttcaat attgataata cagctcatta cattacagac taccaaggat cattattaga
     6841 tgccttagtc actgaacttg cccaacttga taatacttct gctttacaag ttattcaaga
     6901 acgtcgttta ttggcagata gtggcttgat ttcctatgct gaattggttg acttaattgc
     6961 tcaattggac gattctaagt cttatatggt agcagaagcg gttcaacaag tggtctctgg
     7021 tttgaaacgc ttcattgatg aaggaagctt agcagaaaaa tcctttaatc gcttggtaac
     7081 caccatctat caagaagact ttaatcagca tggttttgag aaaaaagctg acgaatcaga
     7141 tgaagatgag atggtacgtc aggttgcctt gggccgcttg tggctagcag aaaatcagac
     7201 gattattgac ggattgagaa ctatttttga agcatatcaa aacaatattg caagtattcc
     7261 agcagctgtt cgtcgcttgg ttttagccaa ccaaatgaaa tattttgaaa cagatagctt
     7321 ggttgatatt tattttgaga cttatgtagc aactactgat aataatttac gcagtgattt
     7381 aacggttgct tttagtcaaa caaaacaacc aactactatt agacgtattc ttgttagttt
     7441 aaaagataaa gatattatta aacctcagga tttatcttat tggtacaatg ctttgcttgg
     7501 acaaagcttt actcaagata tcatttggga atgggctaga gaaaattggg attggattaa
     7561 atctgcactt ggtggagata tgagctttga taaatttgtt atttatccag caagtaactt
     7621 taaaacacca aaacatctag cagaatataa atctttcttt gaacctaagc tagatgatat
     7681 ggctattagc cgtaatatta ccatgggaat taatgaaatt gaagcacgtg ttgctttgat
     7741 tactaaagaa aaagaagcag ttattgcagc tctcagtcat tactagacca taagcaaaag
     7801 agttggggga ctttccagct cttttttgta gtgagctagc ttcctttctt agttccgtct
     7861 ataactaaat gattatccat agtttaattc aaaaggagat tgcactttaa agcgaaggct
     7921 attagcctct taaatacttt tttaccaggt ggtgaataag aacaattata aatgatttaa
     7981 tcattatgct ttaaatgcct taaaggagta ttaatatttt agtaaacctt aagctttttg
     8041 tagtatagtc tcgttagaaa ttgttatcag aaatgagact aagttaaatg aagtgatagt
     8101 tactttattt aagaacaatt gaggtagaga catgataaaa atattattag tagaagatga
     8161 cttgagctta tcaaattcca tttttgattt tttagatgat tttgcagacg tcatgcaagt
     8221 ttttgatggc gatgaaggtt tatacgaagc agaaagtggt atttatgatt tgattttgtt
     8281 agaccttatg ttgccggaga aaaatggctt tcaagtctta aaagaattgc gagaaaaaga
     8341 tattaaaatt cctgtattga tcatgacagc taaagagggt ttagatgata aaggccacgg
     8401 atttgaatta ggtgctgatg attatctgac aaagccgttc tatttagaag agttaaaaat
     8461 gcgaattcaa gcactgttaa aaagaacagg gaaatttgca gataaaaata ttagttttgg
     8521 caatttagtg gttgacttag ctcgaaaaga ggtgaaggtt gaagggaaag tagttgaatt
     8581 acttggcaaa gaatttgatt tgttggtgta tcttttgcaa aatcaaaacg ttattttacc
     8641 aaagacacaa atttttgatc gtttatgggg attcgatagt gatactacga tttcggttgt
     8701 tgaagtttac atttctaaaa taaggaaaaa attaaaaggt acctgttttg ttaacaggct
     8761 tcaaactt
//
LOCUS       DAUGQX010000055         8730 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUGQX010000055 DAUGQX010000000
VERSION     DAUGQX010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8730
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.055"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..547)
                     /gene="speG"
                     /locus_tag="VIA51_001551"
     CDS             complement(<1..547)
                     /gene="speG"
                     /locus_tag="VIA51_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEQ8683489.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     PPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEAVRIKKKQFTLQEFDFKI
                     RKFLMEKYNIYDSESRYTSGSL"
     gene            complement(649..747)
                     /gene="ffs"
                     /locus_tag="VIA51_001552"
     ncRNA           complement(649..747)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VIA51_001552"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            947..2179
                     /locus_tag="VIA51_001553"
     CDS             947..2179
                     /locus_tag="VIA51_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEQ8683490.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNIYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(2793..3308)
                     /locus_tag="VIA51_001554"
     CDS             complement(2793..3308)
                     /locus_tag="VIA51_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEQ8683491.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGVDSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(3308..4087)
                     /locus_tag="VIA51_001555"
     CDS             complement(3308..4087)
                     /locus_tag="VIA51_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8683492.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRNEFA
                     KLSIPDVSEGRAYDVTGVEQIGSFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PDGINSKNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(4227..4766)
                     /locus_tag="VIA51_001556"
     CDS             complement(4227..4766)
                     /locus_tag="VIA51_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEQ8683493.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLSAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(4770..5081)
                     /locus_tag="VIA51_001557"
     CDS             complement(4770..5081)
                     /locus_tag="VIA51_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683494.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCASCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSRAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(5298..6440)
                     /gene="tgt"
                     /locus_tag="VIA51_001558"
     CDS             complement(5298..6440)
                     /gene="tgt"
                     /locus_tag="VIA51_001558"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEQ8683495.1"
                     /translation="MTDYPIKYRLIKAEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            6659..7522
                     /locus_tag="VIA51_001559"
     CDS             6659..7522
                     /locus_tag="VIA51_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEQ8683496.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGSSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDEVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKN
                     PTPMMYDDQKD"
     gene            7719..8730
                     /locus_tag="VIA51_001560"
                     /pseudo
     CDS             7719..8730
                     /locus_tag="VIA51_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2762 a         1767 c         1580 g         2621 t
ORIGIN      
        1 aaaggctccc cgatgtataa cgcgattccg aatcatagat attgtatttt tccattagaa
       61 attttcttat tttaaaatca aattcctgta aagtaaactg tttctttttt atgcgaacag
      121 cctcagaggg caaataagtt tctttcccat cttgatttaa aattcctaca aactgtaatg
      181 atttatttcc ttgattcgaa tgttttacaa taccaccata aatattatct acataaggtg
      241 gggaaaaatt ataagggaga ccaaaaacat cgaccttatc cccttttata aactgatcag
      301 taatgcctaa agatacaata gaatcaacat aaagaataca ttccgatctt ttttgtttag
      361 tattaatatg tatgctattt gtagtaacaa atgcaatttc tacattttca taatcgcatg
      421 gggtaatatt ataggcaaat cttaaacttc tttttaaatc ttttaaattt tcatctgcat
      481 aagctaattg acttccatag ctaaaaacac atgataatat gataattgtc aaaatgtttg
      541 ttttcattta aaacttttta tgtcctgttt tatacctctt agcctaaata aaaatatcaa
      601 tcggtttcaa caactgatga cactatagaa ggaggaaatt actttagtaa agtcaacaaa
      661 aaaagagcac acacccgaaa atcgcttagg gctgctggat tcctcccctg acccacttca
      721 cgcacaagtg ttgctccgcc tattattata tcatattacg gacagtttgc aagttttcca
      781 actaagtaaa atcactttca agtgagcata gcttcatttt gggacaagat ggactgaata
      841 cctagaaaaa tcatgaccct ttccaaacac gattttgctt tttgaaaatc tttccctctc
      901 cccattccag ctattctcta tgttataata agattattag attagaatgg gagttatgat
      961 gaaacaaaag attaaaatct taacagtaat tggccttatg acagttggta tgtctgcgtg
     1021 tcacaacact agcaaacctt ctaataccga ttctgttttt tctttaaccg gaaaaaagcg
     1081 ccaacaaatc gtcaaacaag taagacaacg gtattatttc caacaattat ccaaaaccga
     1141 acaagaaaat tacctcactt tatacgatag tttagcacaa tttcgtgaaa tcatcagttt
     1201 gacgccggct tctaaaaaaa gcttaattaa aacaattgac gcctttgtga tggataatcc
     1261 cgaattttac tggattacat ctgccgatta tcgatttgag ttttctgatc aaacggtctt
     1321 tgtcaccttt cctatcccag aagatgccaa gaacatttat caagacttgc aagcaatcgg
     1381 taatgatatc gtcgcaaaca cgccatcaaa ggatcgctat gagcaggtca aatattttta
     1441 tgaggtcatc attcgagaca cagactacaa taaaaaagcc tttgaagcct atcaatcagg
     1501 cagtcaagcc caggtcgctt ctaatcaaga cattaaaagt gtttttattg atcatttatc
     1561 tgtttgtaat ggctatgccc aagcctttca gtttctttgt caaaaagctg gcattccagt
     1621 cgcctatatc cgtggaactg gtacatctca gcaacctcag caatcttttg cacatgcatg
     1681 gaatgctgtt caaattaata acacttatta tggcgttgat gtcacttggg gtgaccctgt
     1741 ttttgataac catctctcac atcaaaagca aggaactatc aattacagtt ttctatgcct
     1801 gccagattat ctaatggcct tatcacatca gccaagcaaa gacattgctt ttaatactaa
     1861 agaacgtttt gaaaatgttt ggactatacc ttcttgtaca gatgattctt tgctttattc
     1921 taaacgtcat caaagctata tctcaacgtt tgacagtgac gccatccttg caagccttga
     1981 aaatcagttg ttaaatagac aagagccact gtctctacaa tttgctcatc aagatgatta
     2041 tcaacaaatg gtaactgatt taacgacgaa tcaaacaggt tatcataacc ttttcaatca
     2101 gtattggaat aattatacgg gctttaccta tggactctta ccagagactc ttagtatttc
     2161 atttgctagt aggaactagg tttagacaca tgaaacacaa agttaagatg attatctttg
     2221 tcaaacatta caagaaattg atatactaac acaattgaag gcgattatta ttctaaccgt
     2281 cttcaataga tataaccttt tcagattgag cacatctaat gcttgtaaca ttagcaacag
     2341 tgatgagctc ttttttaatg ctttagcaaa atatatcagc taagacaaaa gattaaataa
     2401 ctcaagccat gcctataagt cacttgtttt taatccctgt gtcagtgtca atctacgcaa
     2461 cagataactg acagctctga gccctagaag tctgaacttg ataagtttac taaaaacaaa
     2521 aataaggtga gccattacta tctgttttta gatagtaaat ctttttaaga atgactaact
     2581 catctagtca tcacgtgttt tatttttcga ttgttttcat ctcgattggg tctgaaaaag
     2641 agcgcttcta gtacttggaa acgccctttt gtatattcta tcttcgtatg ttgaatctaa
     2701 caaccattgg aaaaatggtc taacgtttca ctcagtattt tgacaggcta cccttcacca
     2761 aaaatgcatg tgataacaaa ctccttaaaa ctctagtcaa agggatctga ctgttccttg
     2821 atcaaatgct tagctatttt tttgcgctct cgcccttggc ggaaaaaggt ttgcatgatg
     2881 ttagcacagt ctgctgctag caggcctcgt tcaacttgca cgcgatggtt taagcgctca
     2941 tctgtcaaaa tctggtaaag gctgtctact ccaccaaatt tttgattgct ggctccataa
     3001 ataacatgcg gaatccttgc tagcccaatg gcaccactac acatcacaca aggctcgatg
     3061 gtcacaaaga gtgtggtatc taataaacgc cagttgcctt catgagcgtt agcctcgtta
     3121 atagccatca tttcagcgtg cataatggct tggttactct cttcacgcgc attgtgccca
     3181 cgaccaataa tctcaccatc cttgacaatg acacagccaa tggggatttc agctttctgt
     3241 aaggattttt cggcttcttt taaagcctct tgcatgaaat aagtttgctc ttctaaacta
     3301 tatggcatca agaaagactc cccaagttcc aagatttgtg tggtaaggca aggtcaacag
     3361 gaatattacc tgcataggcc tgtgtttctt gcctcaacac ttctaaatgg tttttggaat
     3421 taataccatc tggaggaacc ggtggcatgt gggtcaagac aagcttctta acacctgcct
     3481 ggctagccat tagtcctgct tccttactgg tcaaatgggc catatgattt tcattgcctt
     3541 cgtataagta aacatccgct aagaaaaggt ctgcttcttt tgcgaagtct gccaatcctt
     3601 caaaataacc actgtctcca gtaaagacaa gtacctgacc agtcgctctt tctacaattc
     3661 gaaaggcata acacacaact ggatgaactg ttttaagaaa ggtaatgtca aaagaaccaa
     3721 tctgttcaac tccagtaaca tcataggctc taccttctga aacatcagga atgcttaact
     3781 tagcaaattc gtttcggtcc tcatcatgcc cataaatggg caatacttta ggctgccaca
     3841 ggtgtttagg ataaagttga aaataatggc gcaacacgcc taaatcggcc acgtggtctg
     3901 gatggtaatg gctaataatc actgcatcca aatcgagagg actgatttct ttttccagct
     3961 cattgagcgc tcgactacca gcatccatca ataactgaaa gccgtcatgt cctgtgacca
     4021 aataagaggt tgtgcctgca tcttgatagg gataggctcc ccaagaccct aaggtggtta
     4081 atttcatctc aaacccttct ttcttgcttt aactcttatt ataacaaaaa ttagtgtcaa
     4141 agaggattga gacccaccaa aaacaggtcc tagcagataa atctgccaag acctgttcaa
     4201 cacaacttaa ctatttgatg attagattac tgttttgtat tcaaaaaact atctttgtat
     4261 ttaacagcga taatggtcgc aatgattgct ttgatggtat ctcctggaat aaagaccaag
     4321 tttgataaaa gcgatgtcac aagagacatg ccagtgtagg ctgacaacca gatagcaccc
     4381 agaacatcaa ccagtacaac tcctgagatt aaaagagcta ggaatgctaa tggcgtgctt
     4441 tttgagaacc aattgcggta aagtaatgaa aagacaatag gcacaagaag gtaggcaata
     4501 acatagccag cagatggccc catcaatact ggaatggttg ttcttgagcc tgagaaaaca
     4561 ggtaagaaaa ggccaatcac taaaaataag aaaacagata aggttccctt tttaccaccc
     4621 agcatcaatc cagccaacat gacacctaag ttttgtaaaa caatagggac tgggataaag
     4681 cctagcggga tagcaggaat aaagcctaaa ataataatca aagtggtcat catagccacc
     4741 ttaacaagtt ctttggttgt aaacatcagt tacgactcct ttaaaaaata gatatccttg
     4801 tgcctatgac aggctggatt aaagggactt tgacaataag gacagcatcc acaaccatac
     4861 tcagctcgac tcaagagctt tcgacaatgc ccacaaataa caggagatgt ttcttgatgt
     4921 cctgttggca caaaggcatg atctgttaac tggtcatggc aatggtaaca agcataataa
     4981 gtctgacaag aagcacattt gagcccaaca atatcaagcg gggtatgata atgtaggcac
     5041 cgatactctt ggtcaaggtc aattccaaaa cagtccgtca tatctcatcc tcttgtaata
     5101 gtttaatcaa aagcttatga tttgtcaact ctatttttac aaaagggtaa ctgttttctg
     5161 aaaaagaaca cgtaaaacaa gaacttccct ttaaagagtg acctatcagt tgaaagcaat
     5221 aggacatccg tctatacaaa aaaactgaaa ccaaagacga tagatcgccc tcagttccag
     5281 gatcatagca tttttaatta gaaattacgg tttgatttat tataaccata ccgttcaaga
     5341 aaatcttggc ggaattcaag taagttatcg tccataatag cctgacgtac ttttttcatc
     5401 aagttaacca agaaataaag gttgtggtag cttgtcaaac gaataccaaa agtttcgtcc
     5461 gcttttagca agtgacgaat gtaggcacgg ctatagtttt gacaagtgta gcagtcacag
     5521 tcatgatcaa gtggggtaaa atcttcagcg aatttggcat ttttaatcac aagacgcccc
     5581 tcactagtca tacaagttcc gttacgggcg atacgcgttg gcaagacaca gtcaaacata
     5641 tcgacaccac gaatcacacc atcaatcaag ctatctggtg ctcccactcc catcaggtaa
     5701 cgaggtttat tttctggtaa gaggggagtc gtaaagtcaa ggacggcatt catttcttca
     5761 tggctctccc caacagctaa accaccaata gaataacctg ggaaatccat agccaccaaa
     5821 tctgccgcag actgacgacg aaggtcctca aatccagctc cttgcacaat tccaaataat
     5881 ccttggtcat gaggacgacg atgggctttc aagccacgtt ctgcccaacg gctagtacgt
     5941 tcaatggatt ttttcacgta atcataaggt tggtaaaatt gcgggcactc gtcaaaactc
     6001 atcatgatgt ctgagccaag gttattctga atggaaatgg ctttttcggg tgatagaaac
     6061 atttttgagc cattcaagtg atttttgaaa gtcactcctt cttcagtgat gtttcgtgaa
     6121 tcggctaaag agtaaacttg aaaaccaccc gaatcggtta agattggctg atcccagttc
     6181 ataaacttgt gcagaccacc agagcgagca atcaactcat ctcctggacg caaccagagg
     6241 tgataagtgt ttgataaaat aatccctgat ccaattgctt ttaactcttc tggagactgt
     6301 gttttaacag tagcctgagt tcccactggc ataaacattg gtgtcggaaa ggtcccgtga
     6361 ggggtgataa tttcgcccaa gcgtgcaccg gtgtgctttt ctgctttgat aaggcgatac
     6421 ttaatcggat aatctgtcat gtgctttctt ccttgctatc aagttaaaca gtcttgagct
     6481 tttttgatct gcctgagttt ccatcataat gaagggcttc aagatgacat gttgttctag
     6541 cgcctatcat tttatcaaaa aatccataat ttgtcatgct ttcccaaaaa agtatagtca
     6601 aaataatggt tagctgtctc attttgtttt atggtataat gaaataaagg agtctgttat
     6661 gtcaattaaa gcaatcaaag gccaggctag agacacgtta aaaaatctct ctggcaagta
     6721 tttactattt ttaattccaa cccttctctt tatgtttcat ttcggtattg agattcatca
     6781 aggttacgtc ctatctagtg gtattgaagt ctcgctagcg gctagttatt tcccattact
     6841 actaggactt atccttagcc ttttcatttt atcagcatcc tttacgatga ttgatgttgt
     6901 taggcatttt cgtcagaaag tttcttttgc cgaatcaaca acagccttct caaaagaatt
     6961 ctttgggaac ctgctggttt tagcgatcac taagtggcta ttctttctca tctggtcact
     7021 aatttggttt tttggcctct ttattttcct ttccggactt tcagcgtttt tggtcaatgc
     7081 taaatcaggt agctcaacag tcatttcact gatcttttta ctatttggag cagttttgtc
     7141 cttaattggt tttggtattt atatcaaccg ttattacgct tatagtctat cagaatacct
     7201 tctctacgat gaggttaaag aggggactta tctaggagct atagccgtca ttgaaacaag
     7261 tgtagctatg atgaaaggtt ataaatggaa gctttttttc ctacaactta gcttcaccgg
     7321 ttggtttcta ctgaatattg ttacttttgg gttacttaat atctatcttt taccatattt
     7381 tacaacagcc aatgtcattt tttatgatca actcaagaaa cgtttcaaag acaaagatga
     7441 cccaattgaa ggagaacatt taagccttca tcagcttaat aaaaatccta ctcctatgat
     7501 gtatgacgat caaaaagact aaataaatcc tccatccata aaaatagccc ttgaactgca
     7561 ccccaaaagt tagacacaaa atctaacgat tggggtgcta tttttttatg aaatttaatc
     7621 aagaaacgaa agttaagatt tatgagttac ggcaaatggg agagtccatt aaatccatat
     7681 caaaaaagtt tgatatggca gaatccgatc tcaaatatat gattcgcttg attgataggt
     7741 atggggtaac cattgttcaa aaatgtaaga atcattatta ttctccagaa ctgaagcaag
     7801 agataataaa taaagtcctg attgacggcc aatctcagaa acaaacatcc ttagattatg
     7861 ctttaccaac ttctagtatg ctctcaaggt ggatagcgca atacaagaaa aacggttata
     7921 ctattcttga aaaaccaaga gggagaccga gtaagatggg gcgtaaacgt aagaaaaatt
     7981 tggaagagat gacagaggtt gaacgtcttc agaaggaatt agaataccct agagcggaga
     8041 atgctgtgct aaaaaagctg agagaatacc gcttgaggga cgaagtaaag ctcaaagagc
     8101 aacagaaatc attcaagcat taaggaatca atttccctta gagatgctac ttgaaatcct
     8161 tgatttatca cgctccacct attactatca agtgaagcga ctagctcaag gagataagga
     8221 tatagaacta aagcatgtga ttcgagagat ttatgatgag cataaaggta attacggtta
     8281 tcgtcggatt catatggagt tgcgtaaccg aggatttgtg gtcaatcata agaaagttca
     8341 acgtctcatg aaagtcatgg gcttagcagc ccgcattcgt cggaagcgca agtattcttc
     8401 ttacaaagga gaggttggta agaaggctga taatctgatt aaacgtcact tcgaaggctc
     8461 taaaccttac gaaaaatgtt acactgatgt gacggagttg gccttacctg aaggaaaact
     8521 ctacttatca cctgttcttg atggctataa cagtgagatt attgatttca ctctatctcg
     8581 gtctcctaac ttgaaacagg ttcaaaccat gcttgagaag acttttccag cagattcata
     8641 cagcggaact attcttcata gtgaccaggg gtggcaatac caacaccagt cctaccatga
     8701 ttttttagag tctaaaggta ttctggcatc
//
LOCUS       DAUGQX010000056         8512 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUGQX010000056 DAUGQX010000000
VERSION     DAUGQX010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8512
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.056"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1338
                     /locus_tag="VIA51_001561"
     CDS             <1..1338
                     /locus_tag="VIA51_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8683497.1"
                     /translation="LIVFLPKKLEVATIIFILVFGTISAIISPINDIPDEYVHYSRTV
                     YISEGDINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKATKHSTREYSYPYIKGTNA
                     YYSFSYIPQALGILVGNALDLPILLTYYFGRLCNLISYAMLAFIAIKLSGSFKQVIAV
                     VTLLPMNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKSNYNTKFFLYLVLCGLLV
                     LSKFTYFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFLFAAMWFRLYGQVKTPYV
                     ADFLKEVNVSQQVKNMLESPIVYSSIIIRHMVINLINMNNIFQFGALSYGITNLFPLY
                     VCFFFFVYISNASKITINIVEKMGIIFVISAIIGATVLAMYLTWTPVGSSTVLGVQSR
                     YLIGIIPLVLLLFSSQQQKFKQIEDILSDKLAIHVSLLFILAMLMSTIFRYYH"
     gene            1432..2655
                     /gene="pepT"
                     /locus_tag="VIA51_001562"
     CDS             1432..2655
                     /gene="pepT"
                     /locus_tag="VIA51_001562"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEQ8683498.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSVPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKDRPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            2696..3184
                     /locus_tag="VIA51_001563"
     CDS             2696..3184
                     /locus_tag="VIA51_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEQ8683499.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(3171..3368)
                     /locus_tag="VIA51_001564"
     CDS             complement(3171..3368)
                     /locus_tag="VIA51_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEQ8683500.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            3417..3893
                     /locus_tag="VIA51_001565"
     CDS             3417..3893
                     /locus_tag="VIA51_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8683501.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            3908..4588
                     /locus_tag="VIA51_001566"
     CDS             3908..4588
                     /locus_tag="VIA51_001566"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEQ8683502.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWI
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    4612..4735
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4750..5280
                     /gene="infC"
                     /locus_tag="VIA51_001567"
     CDS             4750..5280
                     /gene="infC"
                     /locus_tag="VIA51_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEQ8683503.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            5322..5519
                     /gene="rpmI"
                     /locus_tag="VIA51_001568"
     CDS             5322..5519
                     /gene="rpmI"
                     /locus_tag="VIA51_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEQ8683504.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            5578..5937
                     /gene="rplT"
                     /locus_tag="VIA51_001569"
     CDS             5578..5937
                     /gene="rplT"
                     /locus_tag="VIA51_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEQ8683505.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(6228..8438)
                     /locus_tag="VIA51_001570"
     CDS             complement(6228..8438)
                     /locus_tag="VIA51_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEQ8683506.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIA
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPKNKE"
BASE COUNT         2780 a         1380 c         1638 g         2714 t
ORIGIN      
        1 ctgatagtgt ttttaccaaa aaagttagag gttgctacga tcatttttat tttagtattt
       61 ggaacgatat ctgctatcat atcacctata aatgatattc ctgatgaata tgttcattat
      121 tcaaggacag tttatatctc agaaggtgat attaatctta ccaacaataa caaaaagtta
      181 agaatatcca aagatgttga taagcttatt aaacagtcag gaaaaacatt tataacatca
      241 aacttgaaag caactaaaca cagcacaaga gagtatagct atccttacat caaaggaact
      301 aatgcatatt atagtttttc ttatatacca caagctttgg gtattttagt aggaaatgcg
      361 ctggatttac ctatactttt aacatattat ttcggaagat tgtgcaacct tattagctac
      421 gctatgcttg cttttatagc tatcaagttg tctggttctt ttaaacaagt gatagctgtt
      481 gttactttac tacctatgaa catttattta gcagcatctt ttaatcaaga cggctttgct
      541 atcggtttag ttttagtaac aattggattg tttattaact tgctctcatc aaaagataaa
      601 tctaactata ataccaaatt cttcctttat ttagttctat gtgggttact agttctttca
      661 aaattcacat actttttatt agtatgcctt ccattattta ttcctaatga aaaattcgga
      721 aaaaatacca agttagtcat cttgaaaaaa ttgggaggac tattactcat ttttcttttt
      781 gctgcaatgt ggtttagact ttatggacag gttaaaaccc catatgtcgc ggattttcta
      841 aaagaagtaa acgttagcca gcaagttaaa aatatgctag aatcccctat agtctatagc
      901 agtattatta ttagacatat ggtaattaat ctgattaata tgaataatat ttttcagttt
      961 ggcgcattaa gctatggtat aacgaacctt ttcccgcttt atgtgtgttt cttctttttt
     1021 gtttatatta gtaatgctag taaaataact attaatattg tagaaaaaat gggtataatc
     1081 tttgttattt cagcgattat aggtgcaact gtattagcta tgtacctgac ttggacacca
     1141 gtagggtcct caactgtctt aggtgttcaa agtcgttatc tgataggaat tatcccatta
     1201 gtgttgcttc tttttagtag tcaacagcaa aagttcaaac aaatagagga tatcctttct
     1261 gacaaactgg ctattcatgt ttcgcttttg tttattcttg caatgttaat gagtactatt
     1321 tttagatatt atcattaaac tcttaattag aggctttaaa aaacttagct tgaataagta
     1381 ttttaaagcc ttttatgcta taattaaatt gagaaattat tgaggtggcc tatgaagtac
     1441 gataacttgt tagatcgatt tataaaatat gtcaaagtga atacaagaag cgttccagac
     1501 agtgagacta ctcctagtac ggagagtcaa gaagcatttg ccttaacgat tttaaagcct
     1561 gaaatggagg caattggttt gcaagatgtt cattataatc cagttaatgg ctatcttatt
     1621 ggaactctgc ctgccaataa tccaaccttg acgcgtaaaa ttggttttat agcccatatg
     1681 gatacggctg atttcaatgc tgaaaatgtt aatccgcaga ttattgacaa ttatcaagga
     1741 ggggacatta cacttggcag ttctaattat aagttggatc caaaagcatt tccaaatctt
     1801 aataattata tcggtcaaac attgattacc actgatggga ctacactttt aggggcagat
     1861 gataaatctg gtattgctga aatcatgaca gcaatagaat tcttgacatc acaaccacaa
     1921 atagagcact gtgacattaa agtggctttt ggccctgatg aagagattgg ggtcggagct
     1981 gataagtttg aggtggctga ttttgaggtg gattttgctt atactatgga tggcggtcct
     2041 ttaggcgaat tgcaatatga aactttcagc gctgcagctc tagaagtgac ttttttaggc
     2101 agaaatgttc atcctggtac ggctaaggat caaatgatta atgcccttga gttagcaata
     2161 gattttcatg agaagctacc tgctaaagat cggcctgaat acacagatgg ttatcaaggt
     2221 ttctatcact taacgggact aactggaaca gttgaagagg cacgcgcatc ttacattatt
     2281 cgtgattttg aagaagcatc atttgaagct agaaaagtga aagttgaaaa tatagctcaa
     2341 tcgatgaatg ctcagctagg aacaaaacgt gtcttggtag agcttaatga ccaatactac
     2401 aatatgaaaa aagttatcga aaaagatatg accgctattg agttagctaa agaagtaatg
     2461 gaagagcttg ctatcaagcc tgtaatcgaa cccatacgtg gaggaacaga tggctctaaa
     2521 atttcattta tgggtattcc cactcctaat atttttgcag ggggtgagaa tatgcacggg
     2581 cgttttgagt ttgttagctt acaaacgatg gagagagctg tcgatgtcat tattggactt
     2641 gtttgcaaag cctaattatc atggaattga tatttagtgg aaggggctta taaaaatgat
     2701 taaactattt ggtaaaataa ggtatcactg gcagccagag ttgtcttggt ctattattta
     2761 ttggtctatt gcgtttgcac ctatttttgt aggtttatct ttgttgtatg agcgcactga
     2821 aatacctagt cgggttttta ttctatttgc tatttttgct gtcctagttg gcattggatt
     2881 acatcgttat ttcattattg aaaataatgg tattttaaga atcgtatctt ttaaattgtt
     2941 tggtccacgt aagctactta tttccactat tactaagatt gaggtgacca aatcaacact
     3001 ttgtctgcac gttgaagata aaagttatct cttttatatg cgcaaatggc ctaaaaaata
     3061 ttttcttgat gccttagcgg ttaatccata cttccaagga gaagttatat taagtgataa
     3121 ctttattaaa ttagactatt ttgaagttta tcagcatgat aaaaaagccc ttactcgagg
     3181 gtaagagctt tagttgggca agatttgaca gctaaaatag cgtccttatc tgaaggacaa
     3241 attgactgac ttgtttcaga tgagcttgaa aatgtgacga taccattgtc atgataatca
     3301 aaaagtgatg aataggtttg gcatagacca caagcgatgc atttttctgg aatgatagat
     3361 actttcataa ctattattct aatatgattt tgttaaatta acaagggggg acgatcatgg
     3421 ctaaagaacc atgggaagaa aaaattgttg atgatactat agggacacga acacgtaaat
     3481 caagaaatgc tttcattagc acgccttggt tgactgcttt attaagtgta ttctttgtca
     3541 tcattgttgc tatacttttt attttcttct atacatcaaa tagcggtagt aatagacaag
     3601 ctgaaacaaa tggtttttat ggagcatcca ctcataaaaa aacaaggaaa gcttctaacg
     3661 ctaaaaaaac atcaagtagt tcaacaacta cagacacaac accttctagc gaagaaacac
     3721 ttgcttctag tgaaggaact ggcgaaaccc ttactgtatt ggcaggtgag ggggcagctt
     3781 ctattgcagc tcgtgcaggt atttctgtgg agcagttaca agcacttaat ccagagcaca
     3841 tgactcaagg atattggtat gccaatccag gagatcaagt cactattaaa taattgaaga
     3901 ggaaaaaatg aaagcaatta aaattgcgat tgatgggcca gcttcaagtg gaaaaagtac
     3961 agtagccaag attattgcaa aaaatcttgg ctatacttat ctagatactg gtgctatgta
     4021 tcgctcagca acttatatcg cactgacaca tggctatacg ggtaaagaag tagcccttat
     4081 cttagaggaa cttgagaaaa atcctatttt ctttaaaaaa gcaaaagatg gctcccaatt
     4141 agtttttctt ggggatgagg acgtgacctt agccattagg caaaatgatg tgactaacaa
     4201 tgtttcttgg atctcagctt tgccagaaat tagagaagag ctggttcatc aacaaagacg
     4261 cattgcacaa gctggtggca ttatcatgga tggtcgtgac attggaacgg ttgttctccc
     4321 agatgcggaa ctaaaaatct ttttagtggc ttctgtcgaa gagcgggcag agcgccgcta
     4381 taaagaaaac ctagaaaaag gaattgaatc agattttgag acgctaaaag aagagattgc
     4441 agctcgtgat tacaaggata gtcatcgtaa ggtttcacct ctaaaagcag ctgaagatgc
     4501 ccttattttt gataccacag gtgtttctat tgatggcgtg gtgcaattta tccaagaaaa
     4561 agcagaaaaa atagttgaca tgtcctagag cctatgttag aatagtaaca atgagaaaag
     4621 tagaagtgag agcttctcgc cttgcgactt aggttgtctg gccctaacat gtcaaattcc
     4681 tatggaatat tatgtgtgcg ggcttgattt atcaagtccg ctttcgtttt tctctaaaaa
     4741 aataaagagg tgaagatcat agctaaaaag gatctattca ttaatgatga aattcgcgtt
     4801 cgcgaagttc gtctcgttgg tcttgaaggt gaacaattag gtattaaacc attgtctgaa
     4861 gcgcaatcat tggctgatgc ttcaaatgtt gatttggttt taatccagcc acaagctgtt
     4921 cctcctgttg ccaaacttat ggactatgga aagttcaaat ttgagtatca aaagaaacag
     4981 aaagaacaac gtaaaaaaca aagcgttgtg actgtgaaag aagttcgtct cagtccagtt
     5041 atcgataaag gtgactttga aacaaaactt cgtaacggtc gtaaattcct tgaaaaagga
     5101 aataaagtta aggtttctat tcgtttcaaa ggacgtatga ttactcataa agagattggt
     5161 gccaaggtac tagctgactt tgctgaagcg actcaagata ttgctatcat tgagcaacga
     5221 gcaaaaatgg atggacgcca aatgtttatg caacttgcac caatttcaga caagaagtaa
     5281 ttgtcacagt ttcattatat ctttaagagg agaatactaa aatgccaaaa caaaaaacac
     5341 accgcgcatc agctaaacgt tttaaacgta caggttcagg cggtttgaaa cgcttccgcg
     5401 cctttacatc acaccgtttc cacggaaaaa ctaaaaaaca acgtcgtcat cttcgtaaag
     5461 ctggtttggt tagctcagga gatttcaaac gtatcaaagc aatggttact ggtctttaat
     5521 tttaaaggca gtagacattt acgagtatta taagaattat ttgaaggaga actattaatg
     5581 gcacgtgtta aaggtggcgt tgtttcacgc aaacgtcgta aacgtatttt aaaattagct
     5641 aaaggttact atggagcaaa acacatcttg ttccgtactg caaaagagca agtgatgaac
     5701 tcttactact atgcataccg tgatcgccgt cagaaaaaac gtgatttccg taaactatgg
     5761 atcactcgta tcaatgcggc tgctcgtatg aacggtttgt catactcaca attgatgcac
     5821 ggtttgaaac ttgctgaaat cgaagtaaac cgtaaaatgc ttgctgattt agcagtagct
     5881 gatgcagcag ctttcacagc tcttgctgat gcagccaaag caaaacttgg caaataagaa
     5941 acgctatacc taaaaaataa ctttctatta cctatagaaa gttataaaga aacaaaaatg
     6001 aaggagacga tggacgtctt ctttttatta tactcaatat aataaaaagc agtttcccat
     6061 gttttattac cagtaatgtg ggatatttag atggtagcaa ggagttttat agctgatttg
     6121 ttttctttag gtctaattag catattttga ttactgataa acttgaatat cgccaataaa
     6181 aaagaagcaa aattattatt ttgcttctag tcagatcatt aaattgatta ttctttattt
     6241 ttggggttat cctcttttag ttcagaagtt gccgcgtcag cttctacggg atttagttct
     6301 aagtaagatg gtgctttaaa aagtttctga gttgatttat gaccattttt actgtataaa
     6361 cttgttgact ctgatccgag ttttgctgaa atatctttca gttgttttaa ctgcttagtg
     6421 tagataaact ggttaggatc aatagctttt agaccatttt gagtatcaaa gcgcaggaga
     6481 tcacccgttt gaatagcgtc gctagctgct agttgttgag caacagcaga gcgaatttcc
     6541 ttagttttgg ctatagtcat ttcatcggga ttagtgattt ctaaacctgt ttgcgtgttg
     6601 tacagacgtc cactatagtt agtgtattca ggagtcatat aagtcccaga tgttcgttgt
     6661 gccacaatct ggctattttg aggtgataat aaatcttgtc ctaattgaac aaactgacta
     6721 gtgtcaatac caagtatgtg gagtaaagta ggaagagcat cgatttcacc gccaaaggtt
     6781 tctttgatac taccattcgt ataacctgga atatggatca tatacgggac tcgttgtagc
     6841 atagcattat catattcaga ccaagtttca gaatctttac caagaagtgg agcaagacta
     6901 gaattacgag aatttgaaat accataatga tcaccatata aaacaaaaat agaattgtcg
     6961 tacaaaccag tggctttcaa gtaatcaaaa aaagatttaa gggcagcgtc taaataattg
     7021 gcagtagcaa agtaaccatt gatcgtttca tcgtctgttt tggctaaagg aaaaccttct
     7081 tcactacttt cgccttttag actagtataa ggatagtgat tactcacagt gataaacttg
     7141 gtataaaaag gttgttgcat ctgttcaaga tattttatgg aatccttaaa catgtactta
     7201 tcatttaacc catattgaaa agagttctta ctattttgtt tagagaagta gctagaatca
     7261 aaaaaataat tatagcccca ttgtttataa gcattattgc gattccagaa agttccaacg
     7321 ttaccatgaa agacagcgct ggtatagcca cctttttggg ctaaaatact tggagtagca
     7381 aattgtgtat tttcaccacc gtagttcacc ataaaagaac cactatttaa accaaataag
     7441 gaattctcca tcatggtttc agcatcagaa gttttacctg ctttaacctg atgaaaaaag
     7501 ttagggaatg ctaaggtagc atttgagtga taaagtgagt tgataaaagg cgttacctca
     7561 tattctttat ctccttcttt tagtttataa tctattaaga attgttgaaa gctttctaaa
     7621 tgaagaacaa taatattttt gccttttcca attccaaaat actgaggatc aggtgctgca
     7681 taatgtcctt tgacataagt tttaacatca attaattctt ctgcagtagc tccatttcgt
     7741 tctttttgag cttgataggt ttgattgccg ctatagaggg taaacgctgg tagtcctaaa
     7801 gctctcacaa tataagtatt tgaaaagcca cgtgttaata gttccggacg atcaatttct
     7861 gctaaaaaaa gattaataga aagcaataga ctagataaag cggtgatggc aaatgctgcg
     7921 cgcttgttaa aaggacgttg atcatttttg atttttttag cgatagataa actaattaga
     7981 ataataaaat caagaatata gataatatcc cagatgcgta aaaggtttaa agcagagtcc
     8041 cctaatccag cggagacttt actactagct agcatggcac tcactgtaat aaagtctgaa
     8101 aattctcggt aatatataga atttgatatc aagagaatgt taaggataat ataaaccacc
     8161 caagaacaga tataaaaggc tcgggtattc ttaacgtaaa gagcaacccc caaaagtaaa
     8221 aaagctagtg ggattggatt gataatagtt agaaagactt ggtatatatt tcccaaatct
     8281 agtgaaaagt ctgtatgata tgcccacagg gtctttatcc agtaacaaaa gagtagagta
     8341 attataaaac ccaatcttgt gttgataaaa cctgtgataa gtgttttaaa tttcttcaca
     8401 gtagcaactt ccttatcgtt ttttcctaaa gatgtcatct ccaaataaaa tctcagatta
     8461 aattatacca aaaatgtgaa gctaatgctt gttgtaagtt caaatttagt ag
//
LOCUS       DAUGQX010000057         8247 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUGQX010000057 DAUGQX010000000
VERSION     DAUGQX010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8247
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.057"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            29..1288
                     /gene="hasA"
                     /locus_tag="VIA51_001571"
     CDS             29..1288
                     /gene="hasA"
                     /locus_tag="VIA51_001571"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HEQ8683507.1"
                     /translation="MPIFKKTLIILSFIFLISILIYLNMYLFGTSTVGIYGVILITYL
                     VIKLGLSFLYEPFKGKPHDYKVAAVIPSYNEDAESLLETLKSVLAQTYPLSEIYIVDD
                     GSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFERSDADVFLTVDSD
                     TYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRLTDIRYDNAFGVERAAQSL
                     TGNILVCSGPLSIYRREVIIPNLERYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQS
                     TARCDTDVPFQLKSYLKQQNRWNKSFFRESIISVKKILSNPIVALWTIFEVVMFMMLI
                     VAIGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMIKHPASFLLSPLYGILHLFV
                     LQPLKLYSLCTIKNTEWGTRKKVTIFK"
     gene            1324..2532
                     /gene="hasB"
                     /locus_tag="VIA51_001572"
     CDS             1324..2532
                     /gene="hasB"
                     /locus_tag="VIA51_001572"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEQ8683508.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2714..3628
                     /gene="hasC"
                     /locus_tag="VIA51_001573"
     CDS             2714..3628
                     /gene="hasC"
                     /locus_tag="VIA51_001573"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEQ8683509.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     GILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
     gene            3936..4349
                     /gene="yaaA"
                     /locus_tag="VIA51_001574"
     CDS             3936..4349
                     /gene="yaaA"
                     /locus_tag="VIA51_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEQ8683510.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIITIVEPSQEEKEQFAEEMAEKTRVAALVKQMNQANKK
                     TSSKHNNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            4351..5457
                     /gene="recF"
                     /locus_tag="VIA51_001575"
     CDS             4351..5457
                     /gene="recF"
                     /locus_tag="VIA51_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEQ8683511.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDELAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(5512..6375)
                     /locus_tag="VIA51_001576"
     CDS             complement(5512..6375)
                     /locus_tag="VIA51_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEQ8683512.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
     gene            complement(6577..8058)
                     /gene="guaB"
                     /locus_tag="VIA51_001577"
     CDS             complement(6577..8058)
                     /gene="guaB"
                     /locus_tag="VIA51_001577"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEQ8683513.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         2817 a         1535 c         1402 g         2493 t
ORIGIN      
        1 ggaaattaaa aaagaaagag gtgtaattgt gcctattttt aaaaaaactt taattatttt
       61 atcctttatt tttttgatat ctatcttgat ttatctaaat atgtatctat ttggaacatc
      121 aactgtagga atttatggag taatattaat aacctatcta gttattaaac ttggattatc
      181 tttcctttat gagccattta aaggaaagcc acatgactat aaagttgctg ctgtaattcc
      241 ttcttataat gaagatgccg agtcattatt agaaactctt aaaagtgtgt tagcacagac
      301 ctatccgtta tcagaaattt atattgttga tgatgggagt tcaaacacag atgcaataca
      361 attaattgaa gagtatgtaa atagagaagt ggatatttgt cgaaacgtta tcgttcaccg
      421 ttcccttgtc aataaaggaa aacgccatgc tcaagcgtgg gcatttgaaa gatctgacgc
      481 tgacgttttt ttaaccgtag attcagatac ttatatctat ccaaatgcct tagaagaact
      541 cctaaaaagc ttcaatgatg agacagttta tgctgcaaca ggacatttga atgctagaaa
      601 cagacaaact aatctattaa cgcgacttac agatatccgt tacgataatg cctttggggt
      661 ggagcgtgct gctcaatcat taacaggtaa tattttagtt tgctcaggac cattgagtat
      721 ttatcgacgt gaagtgatta ttcctaactt agagcgctat aaaaatcaaa cattcctagg
      781 tttacctgtt agcattgggg atgatcgatg tttaacaaat tatgctattg atttaggacg
      841 cactgtctac caatcaacag ctagatgtga tactgatgta cctttccaat taaaaagtta
      901 tttaaagcaa caaaatcgat ggaataaatc tttttttaga gaatctatta tttctgttaa
      961 aaaaattctt tctaatccca tcgttgcctt atggactatt ttcgaagtcg ttatgtttat
     1021 gatgttgatt gtcgcaattg ggaatctttt gtttaatcaa gctattcaat tagaccttat
     1081 taaacttttt gcctttttat ccatcatctt tatcgttgct ttatgtcgta atgttcatta
     1141 tatgatcaaa catcctgcta gttttttgtt atctcctctg tatggaatat tacacttgtt
     1201 tgtcttacag cccctaaaac tttattcttt atgcaccatt aaaaatacgg aatggggaac
     1261 acgtaaaaag gtcactattt ttaaataata tgtgcatcga gtagttagag aaggagtaat
     1321 tttatgaaaa tagcagttgc tggatcagga tatgttggat tatcactagg agttctttta
     1381 tcacttcaaa acgaagtcac tattgttgat attcttccct ctaaagttga taagattaat
     1441 aatggcttat caccaattca agatgaatat attgaatatt acttaaaaag taagcaatta
     1501 tctattaaag caactttaga tagcaaagca gcttataaag aagcggaact ggtcattatt
     1561 gccacaccta caaattacaa cagtagaatt aattattttg atacacagca tgttgaaaca
     1621 gttatcaaag aggtactaag cgttaatagc catgcaactc ttatcatcaa atcaacaatt
     1681 ccaataggtt tcattactga aatgagacag aaattccaaa ctgatcgtat tatcttcagc
     1741 cctgaatttt taagagaatc taaagcttta tatgacaact tatatccaag ccgaattatt
     1801 gtttcttgtg aagaaaacga ttctccaaaa gtaaaggcag acgcagaaaa atttgcactt
     1861 ttattaaagt ctgcagctaa aaaaaataat gtaccagtac ttattatggg agcttcagaa
     1921 gctgaagcag taaaactatt tgccaatact tatttagcgt taagggtagc ttattttaat
     1981 gagttagaca cttacgcaga atcgagaaaa ttaaatagtc acatgattat tcaaggaatt
     2041 tcttatgatg atcgaatagg aatgcattat aataacccat catttggtta tggaggttat
     2101 tgtctaccta aagatacgaa gcaattattg gcaaattaca ataatattcc tcaaacgcta
     2161 attgaagcta tcgtttcatc aaataatgtg cgcaagtcct atattgctaa gcaaattatc
     2221 aacgtcttag aagagcggga gtccccagta aaagtagtcg gggtttaccg tttaattatg
     2281 aaaagtaact cagataattt tagagaaagt gctatcaaag atgttattga cattcttaaa
     2341 agtaaagaca ttaagataat tatttatgag ccaatgttaa acaaacttga atctgaagat
     2401 caatctgtac ttgtaaatga tttagagaat ttcaagaaac aagcaaatat tatcgtaact
     2461 aatcgctatg ataatgaatt acaagatgtt aaaaataaag tttacagtag agatattttt
     2521 aatagagact agccatgtct tcatctataa caataatatt catttttact ttaaaagaac
     2581 tgcagttggt ggtatgattg agcactatga aatagtcgaa aaatcatatg aaaacgtaac
     2641 atgatgtcaa atgaattccg ttctgaaaac gaatgtcact aagccataga ttataaaaag
     2701 tgaggagtta ctgatgacca aagtcagaaa agccattatt cctgctgcag gtctaggaac
     2761 acgtttttta cctgctacca aagctcttgc caaagagatg ttgcccatcg ttgataaacc
     2821 aaccatccag tttatcgtcg aagaagcgct aaaatctggc atcgaggaaa tccttgtggt
     2881 gaccggaaaa gctaaacgct ctatcgagga ccattttgat tcaaactttg aattagaata
     2941 caacctccaa gctaagggga aaaatgaact gttgaaatta gtggatgaaa ccactgccat
     3001 taaccttcat tttatccgtc aaagccaccc aagagggctg ggagatgctg tcttacaagc
     3061 caaagccttt gtgggcaatg aaccctttgt ggtcatgctt ggagatgact taatggacat
     3121 tacaaatgca tccgctaaac ctctcaccaa acaactcatg gaggactatg acaagacgca
     3181 tgcatccact atcgctgtga tgaaagttcc tcatgaagat gtgtctagct atggggttat
     3241 cgctcctcaa ggcaaggctg tcaagggcct ttacagtgta gacacctttg ttgaaaaacc
     3301 acaaccagaa gatgcgccta gtgatttggc tattattggt cgttacctcc taacccctga
     3361 aatttttggt attttggaaa gacagacccc tggagcaggt aacgaagtgc aactcacaga
     3421 tgctatcgat accctcaata aaactcagcg tgtctttgca cgagaattta aaggcaatcg
     3481 ttacgatgtt ggggataaat ttggattcat gaaaacatct atcgactatg ccttagaaca
     3541 cccacaggtc aaagaggact tgaaaaatta cattatcaaa ctaggaaaag ctttggaaaa
     3601 aagtaaagta ccaacacatt caaagtaatg tgttggtact ttactttttt ccttgtttat
     3661 agcaacttaa gtttatatct tgaaaattgt caacgttcca aaatataaaa gttttgtgtt
     3721 atacaacttt actagaggga catattaata ataggattta tacgtagaaa aatgataaac
     3781 ataagtacag cttttgttaa aactaattaa caagaacttc aaaactaaat agttatttgg
     3841 acgagtatga tactttataa atagctctta ttcagctatt attatttatt tctgttttat
     3901 gctataatga cttgaatgac aaaatggaga tgacaatgat atacaaatta tttacagaat
     3961 ttatcaccct acaagccctt cttaaagaat taggaattat ccaaagtggt ggcgctatca
     4021 agggatttct cgctgaaaca accgttctat ttaatggtga agatgagaaa cgtcgaggca
     4081 aaaaaatcag agtaggggat aagatttctc tacctgacca agacttaatt atcactattg
     4141 ttgagcctag tcaagaagaa aaagaacaat ttgccgaaga aatggctgaa aagacacgtg
     4201 tagcggctct agtgaaacaa atgaaccaag ctaacaaaaa gacttcttct aaacataaca
     4261 atcgtcaatc tactaccaaa aaatcactaa gagcaactaa gaaaactaaa ggtaaaccaa
     4321 ctgcacctgt ccgcttccca ggtatctagt atgtggatta aagagttaga gttaaaacat
     4381 tatcgcaatt atgaccacct gcttgcctca ttttcgtcgg gtttaaatgt ctttatcggt
     4441 aataatgctc aaggaaaaac caattttctc gaggcaatct attttctatc acttactaga
     4501 agtcatcgca cgagggctga taaagaattg attcattttg atcactcaac tgtttctctt
     4561 actggtaaga ttcagcgtat tagtggtact gttgatttag aaatcaatct atcagataaa
     4621 ggacgtgtga caaagattaa tgcgctaaag caagcaaaat tatctgatta tattggaacg
     4681 atgatggttg tgctttttgc accagaagat ttgcaactag ttaagggagc acctagcctt
     4741 cgtcgcaaat ttatcgacat tgaccttggt caaattaagc ctgtttactt atctgagtta
     4801 tcccattata accacgtgct taaacagcgt aatagctatt taaaaagtgc ccaacaaatt
     4861 gatgccgctt ttctagctgt tctagatgag caattagcta gctatggagc ccgtgtcatg
     4921 gaacatcgta ttgattttat caatgcgtta gagaaagaag caaatactca tcaccaagcc
     4981 atctcaaatg gtttagaaag tctctctctc tcctatcagt cgtcagttgt ctttgacaaa
     5041 aaaactaata tttaccaaca atttttacac caacttgaaa aaaatcatca gaaagatttc
     5101 ttccgtaaaa acactagcgt tggtccacat cgcgatgaat tagcctttta cattaacggg
     5161 atgaatgcta actttgctag tcaaggtcag caccgcagcc ttatcctttc cttaaaaatg
     5221 gctgaagtta gtttaatgaa ggccttgact ggagataatc ccattctttt actagacgat
     5281 gtcatgagcg agctagacaa tacacgacaa acaaagttac ttgaaacagt aattaaagaa
     5341 aatgtccaaa cctttatcac aacaacaagt ttggatcacc tgtcacagtt gccagaaggt
     5401 atccgtattt ttcacgtgac aaaaggaacc gttcaaattg attctgatat tcactaataa
     5461 catcaaaaaa gggttcagtt aaactgagcc ttttttgata ttatgtggcg attaagattt
     5521 gaccacacct aataaaatag cacctacgat aaaacaaata attcctgtga caacccaacg
     5581 catttctttt ttggttttgg tttcgcctag gaataaaatg cctccgacaa tcgaaatgat
     5641 agcacctaat tgtgagaaac taaaggcaat agcaagtcct gcttttgatg cagctaaaag
     5701 cataaaaata ttcccaatgc cccaaagtaa tccaacaacg ctatttttaa tcacatactg
     5761 gtcaatggaa attttaaatg acatgaaagt tatagctcct aaaaccatac ctactgccat
     5821 gggtaaaatg actgacaaaa cttcaaattt catgatgtta ttaaataata cagcatacat
     5881 cacgtaacca attgttgaat aagtgagcgc cctaaatcct tttgaaaaat tatgaaggtg
     5941 attgacttgt gcattagcat catcttgttt actagaaaag taaaaaccaa caatcagaag
     6001 taatagtgct agacttccta ctacaaattg cataggtctt gtccattcat gaaaaacgag
     6061 gacaccaatc aaacttccca gaacaagttg agagccactt gacaaaggat tggcaacgga
     6121 gactcccatg tattgcatgg catgaaattg accagtttga ccaattgacc agataaaacc
     6181 acccaatatt ccaaaaagcc aaagttgcag tgtcatctca ggtctaacaa ttaaccaaac
     6241 agctaatgaa aataataaag ccccaaaagt cattcctaga gtttgttgcg aaggttttcc
     6301 tccaattttg ttactaacaa atccaatgct tccccatgta aacatgggaa taagtgcata
     6361 aaaaatacct tccaaaatgt tatctccttt atagtaaatc tttaaagatt ataataattc
     6421 catcataaaa tggtttcatg taaagactaa ttatagctta tttactaaga aaaaacaata
     6481 aaagttatcc gaaaattgtt attatatttt atcatttttt aatataaaaa agagctggca
     6541 caatatgtca gcccttaaag ttactaaatt aaattatcag tgcacagaat agtttggtgc
     6601 ttcatttgtg atttggacat catgtggatg actttcaatc aagcctgcac ctgacatttc
     6661 aacaaattga gcattttcat gtaattcttg aatgtcacct gcgccaacat agcccatacc
     6721 tgagcggata ccacctaaca tttggaagac aatatctgaa gcagctcctt tataagcaac
     6781 acggccttca ataccttctg gaactagctt attagcttca ttgacggaac cttggaagta
     6841 acgatcgctt gatcctttct tcatagctgc aatggaaccc attccacgat aagttttgaa
     6901 cttacggcct tggtagattt cagtttcacc tggagcttca tcagtacctg caaacattga
     6961 tccaagcata acagcattac cgccggctgc aagagcctta acaatatcgc cagaatactt
     7021 gataccacca tcagcaataa tcgttttgcc atattcacga gcaacagcag cagcatcgta
     7081 aatagcagtc acttgaggaa caccgacacc tgcaaccaca cgagtggtac agatagatcc
     7141 gggaccaata cccactttaa caacatcaac acctgcatca taaagagcac gcgcaccttc
     7201 agcagtggca atatttccag caatcaaagt acgatttggg aaatgagcac gaatttcagc
     7261 aattttacga agaacaccag ccgaatgacc atgagctgtg tcaataacaa tcgcatctgc
     7321 accagcttca aacaaggcct cggcacgctc aaaagtatct gaggtaacac ctaccgcagc
     7381 agcgaccaga agacgaccaa attcatcttt agcagcatgt gggaattcga ttactttttc
     7441 aatatctttg atagtgatta aaccagacag acgaccgcta ttatcaacca aaggaagttt
     7501 ttcaatacgg tgttcatgaa gaatacgttc tgcagtttca agatctgtac caacagcagc
     7561 cgtaacgagg tgctcactag tcatatgttc agagattggt gcattgtaat cagaaataaa
     7621 acgcatatca cgattagtaa tgataccgac caacttacgg tttgctaaag tttcaacaat
     7681 tggcacacca ctgatacggt agcgctgcat taattcttca gcttctgaaa ccttgtgttc
     7741 aggtgttaag aagaatggat caatgatgac accattttca gaacgtttta ccttgcgaac
     7801 ttcttctgct tgctcagtaa tagacatgtt tttatgaata acacctaaac cacccgcacg
     7861 cgcaattgca atagccattt tactaccagt aaccgtatcc atagctgctg taataatagg
     7921 aatatttaat gtcaaattgt ctgcgagttt tgtctttaaa tcaacttcat ttggaagaac
     7981 atgactctct gccggaataa gcaagacatc gtcaaaagtg tagccttttt tcaaaaattt
     8041 agtgtcccaa tttgacatcc agataatcct cttttctttt atttttaggg aatattaccc
     8101 tggtctattt tttattgtta ctatcatatc acgctaaaat catttgtcaa taaaatattc
     8161 ctacagctga agtcactatc agcataatat atcagtatta tccgtttttt attaatcaaa
     8221 aaattcattt gggtcttatt tttaatc
//
LOCUS       DAUGQX010000058         8236 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUGQX010000058 DAUGQX010000000
VERSION     DAUGQX010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8236
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.058"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            152..850
                     /locus_tag="VIA51_001578"
     CDS             152..850
                     /locus_tag="VIA51_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683514.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            complement(967..2529)
                     /gene="ffh"
                     /locus_tag="VIA51_001579"
     CDS             complement(967..2529)
                     /gene="ffh"
                     /locus_tag="VIA51_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEQ8683515.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENHNDYVLIDTAGRLQIDEKLMGELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(2544..2885)
                     /locus_tag="VIA51_001580"
     CDS             complement(2544..2885)
                     /locus_tag="VIA51_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEQ8683516.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            complement(2974..3672)
                     /locus_tag="VIA51_001581"
     CDS             complement(2974..3672)
                     /locus_tag="VIA51_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8683517.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            complement(3755..5188)
                     /locus_tag="VIA51_001582"
     CDS             complement(3755..5188)
                     /locus_tag="VIA51_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683518.1"
                     /translation="MLRKKRILGLFRLVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKEPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKCYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            5355..6917
                     /gene="guaA"
                     /locus_tag="VIA51_001583"
     CDS             5355..6917
                     /gene="guaA"
                     /locus_tag="VIA51_001583"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEQ8683519.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            complement(6959..8182)
                     /locus_tag="VIA51_001584"
     CDS             complement(6959..8182)
                     /locus_tag="VIA51_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8683520.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
BASE COUNT         2464 a         1569 c         1462 g         2741 t
ORIGIN      
        1 gtacacgaat ctagtcgcta tgttttaggt gttccccctt tttgacagtg ttactatcac
       61 atgaattaat tgtagaaaat gttacacttg ctttcgtttt atttttttga tactattagt
      121 aaagttataa ctttactaaa ggagctacca aatgttttct ggacatcaac taaaaacagc
      181 acgattatca aagggaataa ctcaatcaga attgggaaga ttgttgcatg tcaataaaat
      241 gacaatatct aattgggaaa aaggtaagaa tataccaaat gaaaaacatt taaatgcctt
      301 attgcatcta ttcaatgtga catctgatta tttcgaccca aactatagat tgctaacgcc
      361 ttataaccag ctgacaatat ctaataaaga aaaagtaatt ggctattcag agcgattgtt
      421 aaatcatcaa atagacaaaa aatctaaaga tctcatagat aaaccatcac aattatatgc
      481 ttatcgggtc tatgaaagtt tatctgctgg tactggttac tcctattttg gtgatggtaa
      541 ctttgatgtt gtcttttacg atgaacaatt agaatacgat tttgcgtctt gggtttttgg
      601 agattctatg gagccaactt atttaaatgg tgaagttgtt cttataaaac aaaatagttt
      661 tgattacgat ggagcaattt atgcagtcga atgggatggg caaacatata tcaaaaaggt
      721 atttcgtgaa gatgagggat tacgtctagt gtccttaaat aaaaaatatt ctgataagtt
      781 tgctccctat agcgaagaac ctcgcattat tggcaaaatt atcgctaatt ttaggccctt
      841 agaaatttaa gttagattga taatgaactc atcatggtat gtaacacggt cttccgtaat
      901 tttaataatc ttgtatacaa gataaatgaa tttcacatca aaaagagacg aaaattttcg
      961 tctcttttat tttcgttttt tctttgcttt ttttagtttg ttagcctgcc gtttcatggc
     1021 ctgtttcatg gcaaattggc caatttttcc tttaaaccct ttaccaaata gttgactcat
     1081 atccatatca ccaccaaggc cagataaatc aggcatacca ccttgtccca tcattccttc
     1141 taaggaagac atatctggca taccagcagg catgttttta ggaagattat tgggattaat
     1201 acccatatct ttcatcattt tagacatatc gcccgacata accccttgca tcatgctttt
     1261 ggcttggtta aagtctttga taaatttatt aacttctaca aagctgttcc cggaaccagc
     1321 tgcaatacga cggcgacgac tcgggtttag taagtcagga ttttcacgtt cagcgggtgt
     1381 cattgaagag acaatagcac gtttgcgagc aatttggttt tcgtcaactt tgatattggc
     1441 caaagctggg ttaccagcca ttcctggaat cattttcaag aggtcttcca taggccccat
     1501 attttgcact tgatctaact gttcaataaa atcattgaaa tcaaaggtgt tttcacgcat
     1561 tttttcagct aactctaagg attttttctc atcatattcc tggctagctt tttcaatgag
     1621 ggtaagcaaa tcccccattc ccaaaatccg actggacatg cggtctgggt gaaatgtttc
     1681 aatatctgtg attttttcac caatacctgt aaatttaatt ggtttcccag tgatttcacg
     1741 gacagatagc gccgcacctc cacgtgtatc accatcaatc tttgttaaca caacccctgt
     1801 gatgctcaac tgatgattaa actcgtaggc tacattggca gcttcttgac caatcatgct
     1861 atctacaacc aaaagaattt catttggttg tgctaaagcc ttgacatcgc gcagctctcc
     1921 catcagtttt tcatcaattt gcaagcgacc cgcagtatca atcaagacat agtcattgtg
     1981 gttttcacga gcttgttcca aaccttttct gacaatatcg actgctgagt ggtctgtccc
     2041 catatcaaaa acaggtacat tgatttgttg ccccagtgtt tttaactgat caatggccgc
     2101 tggacggtaa atatcggcag caatcatcag tggtcgcgcg ttttcttctt taattaattt
     2161 attagcgagt tttcctgcaa aagttgtttt accagcccct tgcaaaccga ccatcatgat
     2221 aatagttgga atttttggag atttatcaat ctctgcagtt tctgagccta aaatactcgt
     2281 taattcttca ttaacaatct taagaatttg ttgtgttgga tcaagagtat caataatctc
     2341 atggccaata gcgcgctcac gtacgcgctt aataaaggtt ttaacaactg gtaaagcgac
     2401 atcggcttct aaaagagcta gacgaatctc ttttgtcact tcttgaacat ctgattctga
     2461 taatttcttt ttaccgcgaa tgtgtttaaa cacatcttgc aaacgttggg ttaagctttc
     2521 aaaagccata gtcaaaactc ctcttactct ctattgtcaa tactggttag aatggaaatt
     2581 ttttcttgca aatactcatc atgagggtag tgagcaatca tgtcgtcaaa gatttcactt
     2641 cgaacaacat aatccgaata catatgaagt ttcatctcat aagtctctaa aattttttcc
     2701 gtacgcttaa tattatcata gacagcctga cgactgacac caaattcatc agcaatctca
     2761 gctaagctat aatcatcggc ataatacagt tcaatataat tcatttgttt atctgttagc
     2821 aaagctgcat aaaattcaaa aagggcattc atcctgtttg ttttttcaat ttccataatg
     2881 ttcattttat catactatga ttgtttttaa cagtagcaaa ttaattgcct tgtgctgttc
     2941 gtgtaaaaaa ggaagtcata aatgacttct ttactaatta ttttctaagt aaaattcaaa
     3001 acggtcaccg atatactgac tgcggacata ctcaaaaggt ttgccgtctg taaagtaaga
     3061 cacctgagtt agagccaaaa tggcatgtcc tttagcaact tccaagtagg aggctacacg
     3121 ctcacttgct agcttagcgt agattgtctg tttactttta ccaatctcgt aaccatttgc
     3181 tatcaatgag tgaaaaaagt gttctgtaat atcagctcgt ttaaccgttt ttataaattt
     3241 ttctgggatt gaagcaattt cgtacaccaa agggacactg tctgcatagc ggatacgttc
     3301 cattcgaatg accaagtctg ttttgtctaa gttcaattct ttaacttcgg tatcactagc
     3361 taattgcttt tgataggata ataatttaga ggagggttgt cgtccttggg agcgtataat
     3421 ttctgtgaaa cttgttgttc ctcgcatttt ttcttgaaca cgatgactgg caacataagt
     3481 accacttcct atccgccttt caagaatccc ttcttctact agtaatgtaa tagcctgccg
     3541 tagagtcatt cgactaacgg tgaaatgttc cgctaaatgt cgttcacttg gtaagcgact
     3601 accaattggc cagatgccca gatcaatgtc ttttttaatt gcatcatgaa tttttatata
     3661 agctggtaac atgccacact cctcaagtcg gttattcatc tattttatca tatttttgat
     3721 gaaaattgaa ttgtaaatat tgaggtattt ggcatcaatt aatgatatta cctgcgacaa
     3781 taaccggtga atttggtgga aaatgaatag gttccataaa ccaactagtg agcttcgctt
     3841 tagtaacaat ggatgaggta aaaacattat ttaaaaccct aataactcct acttttgagg
     3901 aatgctgacc aatagaacca ctataggctc tcaggcaacc agtcggatct atataaggta
     3961 aaaattgatt ttggcttaca gtaatattgt gacatagatg tcgagtttgg ttaaatgctt
     4021 catagtttgg agcaatatta ctaagtagac ctccatccca tgcaaaatga tgaacagcag
     4081 catcaaactg aatgacttct gaaaaaaaat catgcccttg agcctttgat agcagctgtt
     4141 ggtcttgtac taattctggc gcatagccaa taaattggtt tttctcaaac aatgaatttt
     4201 gtagagatcc taaatcaaaa atatgactat tacgcttatg aaccatagta aatttgttat
     4261 cgtaaatatg ccaatcagta ccatgatcag ccataatcat aaagtggtct ccttttttca
     4321 aatcatttgc tttgaaatgc actccagtca acacgagatt acgaacacct tgttcagcct
     4381 ttggtcctgt agggaatcca aaccacaaca ttttaccgtg aataatgaac tctgtctgat
     4441 gaccaataat agctgtatca gatggaagct caaaataatc tttttgtgaa ggcaaagagc
     4501 caatgtgaaa ttgccccttt ggaaaagata taacgctatt tggatgctgc tttgcataag
     4561 cgaaagcttt tcgcaaaaga cgattgtttt gctcagggga atttccttta ttgaacctaa
     4621 tataataagg tttaacaaaa tcttgctctg aaattccatc taatcttaga ttatctttca
     4681 gattaatatc gtactgatat cctcctaacg aatagtcata gcatttttta acttgtttaa
     4741 tagtcgctaa ttgaccttga tatactttta tatgtggctt tttagttaat gaagataatt
     4801 taacgatatc tcctttttta aacctcggtt tatcaggctc tttcaggtta tgttctggca
     4861 aagaaacagt gacttttcct attggaaata ccacttcata atgataactc actcggtaat
     4921 tttcggctat atcttctacc tgtttattaa tagttccaat ccattgatga tatggaccac
     4981 ttttttgtac ttgaatagct tgtccaatgt gatagcgagg ctgttgatct ttgcttcgtt
     5041 ccactattcc gacagttgct aatatattat gaagtgttgc aaaactattg gtccacgcaa
     5101 ggtacgaaac aactaaactc aacaataatc ctaggaaaat taattcaaca agtcgaaata
     5161 aacccaaaat tctctttttt cttagcatag gccctccctg ttgtcttaat tccctttcat
     5221 agcctctatt gtaacataac gattacgttt ttttccaacg agctagagaa attgtaatgt
     5281 cttttcgatg aaaatatgct acaataagtt gacaactatc aacctgacgg ttggtataga
     5341 atgaaaggat tataatgact gaaatttcaa ttttgaatga tgttcaaaaa attatcgttc
     5401 ttgattatgg tagccagtac aatcagctta ttgctagacg tattcgagag tttggtgttt
     5461 tctccgaact aaaaagccat aaaatcaccg ctcaagaact tcgtgagatc aatcccatag
     5521 gtatcgtttt atcaggaggg cctaactctg tttacgctga taacgccttt ggcattgacc
     5581 ctgaaatctt tgaactaggg attccgattc ttggtatctg ttacggtatg caattaatca
     5641 cccataaatt aggtggtaaa gttgttcctg ctggacaagc tggtaatcgt gaatacggtc
     5701 agtcaaccct tcatcttcgt gaaacgtcaa aattattttc aggcacacct caagaacaac
     5761 tcgttttgat gagccatggt gatgctgtta ctgaaattcc agaaggtttc caccttgttg
     5821 gagactcaaa tgactgtccc tatgcagcta ttgaaaatac tgagaaaaac ctttacggta
     5881 ttcagttcca cccagaagtg agacactctg tttatggaaa tgacattctt aaaaactttg
     5941 ctatatcaat ttgtggcgcg cgtggtgatt ggtcaatgga taattttatt gacatggaaa
     6001 ttgctaaaat tcgtgaaact gtaggcgatc gtaaagttct tctaggtctt tctggtggag
     6061 ttgattcttc agttgttggt gttctacttc aaaaagctat cggtgaccaa ttaacttgta
     6121 ttttcgttga tcacggtctt cttcgtaaag acgagggcga tcaagttatg ggaatgcttg
     6181 ggggcaaatt tggcctaaat attatccgtg tggatgcttc aaaacgtttc ttagaccttc
     6241 ttgcagacgt tgaagatcct gagaaaaaac gtaaaattat tggtaatgaa tttgtctatg
     6301 tttttgatga tgaagccagc aaattaaaag gtgttgactt ccttgcccaa ggaacacttt
     6361 atactgatat cattgagtca ggaacagaaa ctgctcaaac catcaaatca catcacaatg
     6421 tgggtggtct ccccgaagac atgcagtttg aattgattga gcccttaaac actcttttca
     6481 aagatgaagt tcgagcgctt ggaatcgctc ttggaatgcc tgaagaaatt gtttggcgcc
     6541 aaccatttcc aggtcctgga cttgctatcc gtgtcatggg agcaattact gaagaaaaac
     6601 ttgaaaccgt tcgcgaatca gacgctatcc ttcgtgaaga aattgctaag gctggacttg
     6661 atcgtgacgt gtggcaatac tttacagtta acacaggtgt ccgttctgta ggcgtcatgg
     6721 gagatggtcg tacttatgat tataccatcg ccattcgtgc tattacgtct attgatggta
     6781 tgacagctga ctttgctcaa cttccttggg atgtcttgaa aaaaatctca acacgtatcg
     6841 taaatgaagt tgaccacgtt aaccgtatcg tctacgacat cacaagtaaa ccacccgcaa
     6901 cagttgaatg ggaataacag aataaacatt aaaagactcg ccaaaatgag cgagtctttt
     6961 aatgtttatt ctttaactgt tttcgtattt tgtacatggt attagcaata tgataaagtg
     7021 ggctgacagg gagattaaat tctcctataa attcttctat tgtcggagca aagttggcct
     7081 taaatttggt aagtccatca tcaagcgagc cttctactcc tcccatgtta gcccaaataa
     7141 taccatcttg ataagcatcc tgaaaaacat taggatacag cagatactga ggataaaact
     7201 tcttaaaatc atcattcatc ccagcataaa gcatttccat aacatttcca taagaaatag
     7261 ataatatacc tgctacaaca acttcctcag gatattggtc tgtaaagcct tcaaattcag
     7321 ttatataacg ttctaaagaa gctttttgat cttctaattt ttttaaacgc ttcttttgat
     7381 gagcttgggt gcgagtaata tcttggttaa taagaattaa ttgctggcgg tattgatcta
     7441 gtttttgagg aatattcact tttgctagat gtaagtaggc cttatcccca taagtagtca
     7501 tcaacttttg aaagtaagct tcgttacgca aagaaatatt tttacgtttt tctgttaagg
     7561 agacaatctt ggaaaatttg tgaagttctg attgactgac acgatatgtt tttacaccac
     7621 gctgcttagc atcttttatt aaacgtctgg tatgcttagg aaattgcatc tcaaggtttt
     7681 cttgagtgta aatattagct tggaaacgag gttggatact atctgcaatc tccattgtta
     7741 aaccagtcca atgaacacca gcttcttgga gattcttaat agctgctaaa gctaaaggtt
     7801 tttcttcttc ttcctgtccc agtgcgtatt gttttaacag gatagctgga tcatatttga
     7861 taaagagggc ctttttagtt ttaccataat cctttagtgt tttcatggta aatgccacca
     7921 aatcacggtc aagataatcc atgactggcc ctcttggaat ataaataatg cttcttccaa
     7981 gtggcaatag cttaatcaaa agtgataaag aggcaacctg cttttcctct ttatagatac
     8041 caattcgctc attctgccat tgatttttga tttttgccca atcactacct tgtaaaacgc
     8101 taatttgctg atgttcttta acaaaagagt catgctcttc ttctgaaata ccgatttttg
     8161 cataaaacgt taaattcgtc atttattgtc cccatctatt cgtaatctta gcagatgtac
     8221 ttactaatca tcttta
//
LOCUS       DAUGQX010000059         7548 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUGQX010000059 DAUGQX010000000
VERSION     DAUGQX010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7548
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.059"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            28..879
                     /locus_tag="VIA51_001585"
     CDS             28..879
                     /locus_tag="VIA51_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEQ8683521.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSNSNVTLPWYKK
                     ILGGKSK"
     gene            876..1832
                     /locus_tag="VIA51_001586"
     CDS             876..1832
                     /locus_tag="VIA51_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEQ8683522.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            1886..3241
                     /locus_tag="VIA51_001587"
     CDS             1886..3241
                     /locus_tag="VIA51_001587"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEQ8683523.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     TRPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            3375..4016
                     /locus_tag="VIA51_001588"
     CDS             3375..4016
                     /locus_tag="VIA51_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683524.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQMLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            4079..5209
                     /locus_tag="VIA51_001589"
     CDS             4079..5209
                     /locus_tag="VIA51_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEQ8683525.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            5219..5971
                     /locus_tag="VIA51_001590"
     CDS             5219..5971
                     /locus_tag="VIA51_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEQ8683526.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            5971..6735
                     /locus_tag="VIA51_001591"
     CDS             5971..6735
                     /locus_tag="VIA51_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEQ8683527.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHIETSIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            6735..7367
                     /locus_tag="VIA51_001592"
     CDS             6735..7367
                     /locus_tag="VIA51_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEQ8683528.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDSVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
BASE COUNT         2304 a         1322 c         1612 g         2310 t
ORIGIN      
        1 cttttttgat atagaaatga gagttgtatg aataatttat ctagtatcga tattaaattt
       61 ttattaagct tatttgcgga tccttggctg ctggcagtgc atcttttaga tattctaatt
      121 gttgcctatt tgatttatcg ttttattaaa gcattgactg gaactaaaat catgtcttta
      181 gttcaagggg tcattttctt tttggttctt cgttttattg cagagtggat tggctttacg
      241 acaatcacat acttaatgaa ccaagtcatt acttatggtg taattgcagg agtagtcatt
      301 tttacccctg aaattcgggc aggactggag aaatttggtc gttctacgca agttttttta
      361 caaaaacagt acgtcagcag tgaatctgct ttggtcgatg ctttgattaa atctgtggcc
      421 tatatgggtc cacgcaagat aggtgcattg attgctattg aacagactca aaccttacaa
      481 gaatatattg cgacaggaat tccgctgaat gccgacattt caagtcaact actcatcaat
      541 atttttattc cgaatacgcc gcttcatgat ggagctgtta tcgttggtca gaataagatt
      601 gtggcagcct gtgcttactt gcctttgtca gaatcaaagg caatttccaa agaatttggg
      661 acccgtcata gagcggctat tggattatct gaaaactctg atgcactaac tatcattgtt
      721 tcagaagaaa caggagctat ttcagtaact cgcaaaggcc aatttttaca cgatttaagc
      781 acagatgaat ttgaaacggt acttaggacc tacctgatga gtaattcaaa tgttacttta
      841 ccatggtata agaaaattct aggagggaaa tctaaatgaa acgattttta aatagtcgtc
      901 cttggttagg aatggtatca gtcttttttg cgattctcct ttttttaact gcagcatcga
      961 gcaatcataa taactctagc tcgcaaatct atagtccgat tgaaacctat acgcatagcc
     1021 ttaaagatgt accaattgat atgaagtatg atagtgacaa atattttatc agtgggtatt
     1081 cttatggtgc ggaagtttat ctaacctcca ctaatcgtat caaattagat tctgaagtga
     1141 acaatgatac acgtaatttt aagattgtgg cggatctaac acatagtcat ccaggtacag
     1201 taagtgtcaa cctaagagta gaaaaccttc cttctggggt gacagctacc gtatctccag
     1261 ataaaatatc agtcacaatt ggcaaaaaag aatctaaggt atttcctgtt agaggaagcg
     1321 ttgatgctaa acaaattgca aatggttatg aaattagcaa aattgaaacg ggggttaata
     1381 aggttgaagt gaccagtgat gaatctacca ttgctttaat tgatcacgtt gtggcaaagt
     1441 tacctgatga tcaagtgtta gataggaatt atagtagtcg agtgacctta caagctgtct
     1501 cagctgatgg aactatttta gcaagtgcaa ttgatcctgc aaaaacaaat ttatcagttg
     1561 ctgtaaaaaa aataacgaaa tcagtcccga ttagagttga ggcagtgggg atgatggatg
     1621 atagcttatc agatattcaa tacaaattgt caaaacaaac agctgttatc tcaggtagtc
     1681 gagaggtctt agaagatatt gatgaaatta ttgcagaagt taacatttct gatgtcacta
     1741 aaaatactag taagaccgtg agtttgtctt ctagtcaggt gtcaattgag ccgtcagtag
     1801 tgaccgttca gttgacaacc accaaaaaat aatggataat aactaggaaa attgaatgga
     1861 ggaagccatt aggcttatat aaattatggg aaaatatttt ggaacagatg gtgttcgtgg
     1921 cgaagcaaat gttgagctga cacctgagtt agcttttaaa ctgggccgat tcggtggtta
     1981 tgttttaagt caacatgaga ccgaaagacc taaagttttt gtggcgcgtg acacccgtat
     2041 ttcaggagaa atgttggagt cagccttgat tgctggtcta ctatctgttg gtattgaagt
     2101 ttataaactt ggcgttttag cgacacctgg tgtctcttat ttagttagaa cagaaaaagc
     2161 aagtgcaggt gtgatgattt ctgcaagtca taaccctgcg cttgacaatg gcatcaaatt
     2221 ctttgggaat gatgggttta agttagctga tgaccaagaa ttggaaattg aagctctctt
     2281 agatgctccg gaggacacgc ttcctcgccc gagtgcagaa ggacttggaa ccttggtaga
     2341 ttatccagaa ggacttcgta aatatgaaaa gttcttggta acaactggta ctgacttaag
     2401 cggtatgaca gttgccttag acactgctaa tggagctgct tcagtgtcag cacgtgatgt
     2461 ctttttagat ttaaatgcag aaattgctgt cattggtgaa aaaccaaatg gtcttaatat
     2521 taatgacggt gttggttcaa cgcgtccaga acaacttcaa gagttagtta aggaaacagg
     2581 agcagatctt ggtttagcct ttgatggcga tagcgaccgt ctgattgctg tggacgaaac
     2641 tggcgagatt gttgacggtg atcgtattat gtttatcatt ggtaaatatt tgtcagaaaa
     2701 agggcttctt gctcacaata ccattgtcac aacggtgatg tctaacctcg gttttcataa
     2761 agctttagat aaacaaggta ttaataaagc aattacagca gttggagacc gctatgtggt
     2821 tgaagaaatg cgtagctcag gatacaatct cggtggtgaa caatcaggcc atgtcattat
     2881 catggactac aataccactg gagatggtca gttgacagct atccaattag ccaaggtgat
     2941 gaaggaaact ggaaaatcac tttcggaatt agctgctgaa gtaaccattt accctcaaaa
     3001 actggtgaat attcgtgtgg aaaacagcat gaaagaacgt gctatggaag ttccagctat
     3061 tgcgaacatc attgcaaaaa tggaggatga aatggctggt aatggtcgta ttctcgtgag
     3121 accaagtggt acagaacctc ttcttcgtgt catggcagag gcgccaacag atgccgaagt
     3181 tgattattat gtcgatacta ttgctgatgt cgtccgtaca gaaatcggat gcgataacta
     3241 acgagttgag tacaaacaag aaaccttatt tctaaggctt ctgtcaacaa ttggaaagag
     3301 gcttggggcg tttagcccaa gtctcttttt ataaattgtt ataaattgct aaagtagaag
     3361 agaaaggata ttggatgaca aaacagcaaa tcgaaaaact agcggactta ctgcctcctt
     3421 ttgcagccac actttactta gacatgattc ctgaatttca agaaggttat gcttcttatg
     3481 tttatcaaac accaaaacaa gatattcaaa agcgccgcat caagcagtta actaaaaatt
     3541 ttgaacgatt actagatacc ccatcttttt atgtgatgcc tgtgacaaga aaaacagcag
     3601 agcaattgct agcagataaa ggcctagctt atcatttgtt atcgacagtt gcagctaatc
     3661 aagtgtttgc ggctgctgtt aacgaggatc agatgctttt tcaagtgctt cgaaatggag
     3721 caagagtagc ctttgtgatt cttcaagaaa agggggaatt tctagaaatg actttaggga
     3781 ttcttgaaac agtgacagaa aacgaggttc cagcagctat tgtggaggct gtccagacat
     3841 atcttctggc agatatgcaa gagaaactcc cttctttaag cattatggtc agtcaagaat
     3901 caagcaagct tttttaccaa gaacaagggt ttgttttgct agctaagggt tgcaagccag
     3961 gaaacgaaaa tgattctgac gtttgtcagc tcgtaaaata cttttccaag ccatgaagaa
     4021 tcaagggaaa tggtttattc atagaaacat tttatcatca aagtggtata ataagaccat
     4081 gtcaaaaaaa cctacttcag cctatgtgca cattcctttt tgcacacaaa tttgttatta
     4141 ttgcgatttt tcaaaagtct ttatccaaaa tcaacctgtt gatgcttatt tgaaagcctt
     4201 gattcaagaa tttgactctt atggcattcg agacctaaaa accctttata ttggaggagg
     4261 tacgcctaca gctatcactg ctaaacagtt ggagtatctc ctaaatcacc ttgaacgaaa
     4321 cctcaattta gatgatcttg aagaattcac aattgaggca aatcctggtg atttgacgcc
     4381 agaaaaaatt gcggtgcttc agaggtcagc tgtcaatcgg atttccttgg gggtgcagac
     4441 ttttaataac aagcaattaa agcagattgg ccgtagccat aatgaagaac aaatttatag
     4501 caccattgcc aatttaaaaa ctgcaggctt tcacaatatt tccattgatt taatttatgc
     4561 cttgccaggt caaaccttag atcaagtcaa ggaaaatgtt gctaaagctt tggcacttga
     4621 tattccccac cttagtcttt atagccttat tttggaacat cacactgttt ttatgaacaa
     4681 aatgcgacgt ggtaaactta acttaccaac ggaagacttg gaagcggaaa tgtttgagta
     4741 cattatttca gaaatggaag ctaatggttt tgagcattat gaaatttcca attttaccaa
     4801 accaggtttt gaaagtcgcc ataacttgat gtattgggat aatgtggagt attttggatg
     4861 tggtgcaggg gcttcaggtt accttaatgg cattcgttat cagaatcggg tgcccatcca
     4921 gcattatctt aaagcggttg aagcagggaa tgctagacta aatgaagaag tgctgcgcaa
     4981 agaggaaatg atggaagagg aactcttttt gggcttacgt aaaaagacag gagtctccat
     5041 ccagcggttc caagaaaaat ttggtatgtc ttttgaggag cgttatggaa atattgttag
     5101 ggagcttcaa aaccaaggac tgcttgtcaa agatgacgcc tttgtcagaa tgactaaaaa
     5161 gggtcttttc ttaggtgatt ctgttgctga gcggtttata ttagattagg agagtattat
     5221 gggattaagt tatcaggagg agttgacact tccttttgaa ttatgtgatg tcaaatcaga
     5281 tataaaattg ccccttttat tagactattg tttgatggtt tctggtagac agtctgcgca
     5341 attaggacga agtaacaaca atcttttagt tgattacaag cttgtttgga ttgtaacgga
     5401 ttatgagatc actattcatc gcttgccaca ttttcaagaa accatcacca ttgaaacaaa
     5461 agccctttcc tataataaat ttttttgtta tcgccaattt tatatttatg atcaagaggg
     5521 gggtctttta gtggatatct tagcctattt tgctttgtta aacccagata cgcgaaaagt
     5581 ggcaactatt ccagaagatt tagtagcgcc atttgagact gattttgtta aaaagctaca
     5641 ccgtgttcct aaaatgcctc ttttagaaca atcaattgat cgtgattatt atgtgcgtta
     5701 ttttgatatt gatatgaatg gtcatgtcaa caacagtaaa tatttagatt ggatgtatga
     5761 tgtgttgggg tgtgagtttt taaaaacgca tcagcctctt aagatgactt tgaaatatgt
     5821 taaagaagtc tcaccaggcg gtcaaattac ttccagttac catttggacc aattaacttc
     5881 ttaccatcaa atcacctcag atgggcagct gaatgcccaa gccatgattg aatggcgagc
     5941 gattaaacaa acagaaagcg agacagacta gtgccttata agggttattt aattgattta
     6001 gacggaacga tttaccaagg gaaaaaccgt attccagcag gggagcggtt tatcaaacgc
     6061 ctacaagaaa gaggcattcc ctatttatta gtgactaata ataccacaag aacacccgaa
     6121 atggtgcaaa gcatgctggc taatcagttt catattgaga caagcattga gaccatttat
     6181 acggctacca tggcaaccgt cgattacatg aatgacatga accgtggcaa gacagcttac
     6241 gttattggag aaacagggct caaatcagct attgcagcag caggttacgt agaagaactt
     6301 gagaatcccg cttacgtggt ggttggttta gacagtcagg tgacctatga gatgttggct
     6361 atagccacct tggctattca aaaaggtgcc ctctttattg ggacaaatcc tgatttaaac
     6421 attccaaccg aacgtggttt gatgccagga gcaggtgcat tgaatgcctt actagaagct
     6481 gccacacgtg taaaacctgt ttttattggc aagcccaacg ctatcattat gaataaatca
     6541 ctagaggtat tgggcattca gcgctctgag gctgtcatgg ttggcgataa ttacttgact
     6601 gatatcatgg caggtattca aaatgatatt gcaacgatcc tcgtgacaac aggctttacc
     6661 agacctgaag aggtaccaac cttaccaatt cagccagatc atgtcctatc cagccttgat
     6721 gagtggaggt tgtgatggta gaaaacacta aattactatg tagctgggta tggttattag
     6781 cgttagctat tctcataacg atctattcaa cgtggctgtg gtatcctctt gaggtggacc
     6841 atctaaagtt agaacaagtt gtttttatga gcaaggatgc tatcttgcat aactataacg
     6901 gactactcaa ttacctcacc aatccttttg tgacaaggtt ggaatttgct aattttcact
     6961 catcggcaga cggactcaag cattttgcag atgtgaagtg gctttttcac ctaactcaag
     7021 tcgtttttct tggccttctt tacccaaccc ttaagacttt cacacaaagg ttaaaaacca
     7081 aacgtttctg gctccttcaa aaacctttaa tactagcagc tttgtttcct cttatgattg
     7141 gtctaatggc tagtttcatt gggtttgaac atttttttac tctttttcat caggtgcttt
     7201 ttgtaggaga tagcagctgg ctctttgatc ccttgaaaga ttctgtgatt tggatccttc
     7261 cagaagtctt tttcttgcac tgtttccttt tctttatgat agtttacgaa atcatcctgt
     7321 ggagcttagt aggtttagca agatggcagc gcctaaatgt agaatgataa aaggattaag
     7381 agattaattt ccctaaaaat gataaaacaa gcgttttgaa agcgcttgtt tttttggttt
     7441 gcagtcagag tagaatagaa gtatcaaaaa aagcaccgac tcggtgccac tttttcaagt
     7501 tgataacgga ctagccttat tttaacttgc tatgctgttt tgaatggt
//
LOCUS       DAUGQX010000060         7447 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUGQX010000060 DAUGQX010000000
VERSION     DAUGQX010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7447
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.060"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(536..808)
                     /locus_tag="VIA51_001593"
     CDS             complement(536..808)
                     /locus_tag="VIA51_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEQ8683529.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            complement(825..2186)
                     /gene="dnaB"
                     /locus_tag="VIA51_001594"
     CDS             complement(825..2186)
                     /gene="dnaB"
                     /locus_tag="VIA51_001594"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEQ8683530.1"
                     /translation="MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFY
                     KYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANA
                     EYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFR
                     KISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTA
                     FVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNV
                     TIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPEN
                     RQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADI
                     VAFLYRDDYYRKECDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQF
                     EER"
     gene            complement(2222..2674)
                     /gene="rplI"
                     /locus_tag="VIA51_001595"
     CDS             complement(2222..2674)
                     /gene="rplI"
                     /locus_tag="VIA51_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEQ8683531.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            complement(2671..4647)
                     /locus_tag="VIA51_001596"
     CDS             complement(2671..4647)
                     /locus_tag="VIA51_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEQ8683532.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNGLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKCLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKYLLLKTINMTMKETGEVES"
     gene            complement(4738..6636)
                     /gene="mnmG"
                     /locus_tag="VIA51_001597"
     CDS             complement(4738..6636)
                     /gene="mnmG"
                     /locus_tag="VIA51_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEQ8683533.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPIKETNDRVQDLGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPTNIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            complement(6760..7077)
                     /locus_tag="VIA51_001598"
     CDS             complement(6760..7077)
                     /locus_tag="VIA51_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8683534.1"
                     /translation="MIVRNGKNFLTRDADDQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRAKVNQLAFMVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
BASE COUNT         2282 a         1542 c         1142 g         2481 t
ORIGIN      
        1 ctatcatctg atgatcagtt taatatttta aggtcagata tgagacgaac caccactgat
       61 gaattaagaa gactatatta taagaagtta tagttatggt aataaagaca actgtcatta
      121 acaaaaaata atttaaatgc taatttgcag ttcttaaacc ttgactgttt ttttcttagc
      181 tctctatcaa aagcacttca ctggaaactc ttaatggctc tgaaatggct agtatattgt
      241 atttatcagg ggaggtttac tcgtttgttc acttcaagat agttttaccg gatacttcaa
      301 gctcctctat taattacact tgtgtcaaaa ctttatttca cgataatctt ttaaccttag
      361 tactaagatc atttgcttaa ccatggtgaa gacctctttt ttccttcaat ctaacctaaa
      421 aatattatct tttataggaa ttttttcaaa ataaaaagaa tacaggcaga ataatcttct
      481 atcgctaata attatatcaa tttattgtaa agaaaaagcc tctatgaggc aaaaatcaat
      541 ctaaataacg aattaatgtt ttttctgtca aaatatctga ataggtgtat gattcgacat
      601 aagaattatc aattgctcct ggagtatcag agctatcact atactcaatg ataaagagtg
      661 aactgtaaac ttcaataagc ctaccaattt tatttttttc ccgtttccgt ccattctcaa
      721 gggttaattc tactaactgt ccttcatggg ctcttatgtc ctctttaatt tttttcattt
      781 ttgcaacatc tgtaaatgca tcgctcattt tttgtctctc tttcttatct ttcttcaaac
      841 tgggctatac ttgagaattt gttgtattct ttttggaaca tcagtttgac tgttccacgc
      901 gccccagctc tatttttctc gaggataact tcaattgtgt tatcttcaac agcttcttca
      961 gcatcatcac attctttacg gtaataatcg tcccggtata agaaggctac aatatcggca
     1021 tcctgctcaa tagatcctga ttcacgaata tctgataaaa ctggtcgttt atcttgcctt
     1081 tgctcaacgc cacgagaaag ctgacttagg gcaataactg gtactttcaa ttctttagct
     1141 aggattttaa gctgtcttga aatatctgaa acctcttgct gacgattttc gggtttagtt
     1201 cctgtaatca actgtaagta gtcaattaca atgagaccta aaccaccatc cacttcttga
     1261 gacaatttcc gtgatcttgc gcggatttca gtaattttaa tcccgggcgt atcgtcaata
     1321 taaatcggtg cttctgccaa agctccctga gcaattgtta cattattcca atcctgatct
     1381 gtgagttgcc ctgttcttaa actgtgcgaa tcaaccattc cttctgctgc aagcatacga
     1441 tctactaaac tttcagcacc catttccaaa gaaaaaatag caacagtctt tttttgctta
     1501 gtccccacat tttgcgcaat attaagaaca aaggcagtct tccccactgc tggccgagca
     1561 gctaaaataa ctaattgatc tgggtgtaaa cctgttgtaa tcttgtcaag gtctctaaaa
     1621 ccagttggta aacctgtaac atttgaagtc tgcttagaac gtgcttctaa agcctcgtaa
     1681 ttaactttta gcacatctga aattttgcga aacccactac gattactatg ttcattgagt
     1741 tcaattaaag ctctctcaac tccagcgata acctcttctg gttttaaaat ttcatcataa
     1801 gctaggttga cagattctgt caacctagca ataatatcac gcaacatagc tttctcagct
     1861 acaattttag cataatattc tgcattagca ctagttggga cactattaac tagttcaaca
     1921 atataggata agccaccaat actttgcaga tcatcttgat catctaggat tgttcttata
     1981 gtggttgcat caatggcatc attacgatcg ctgagggtaa tcattgcccg aaagataatt
     2041 ttatgagcgt acttataaaa atcgtctgga ctgataaatt ctctcactgc aatcagctta
     2101 tcaggtgaga taaagattga cccaagaaca gattgctctg ctagtaaatc ttggggttga
     2161 actcgtaatt cagctacttc aggcaacttc ataacctcca aatcttgtga tgttttttat
     2221 attatgcttc tgtgatagcc aatttaatct cagctgttac ttccttatgt aatttcacag
     2281 gaacttcaat tagaccaatg gcgcggatag gatgatctaa aacaatatga cgtttatcaa
     2341 cttttacacc aaattgcttt tgcaattctt ctgaaatctt tttagctgtg atggaaccaa
     2401 atgtacgtcc atctggacca actttttctt gaaattgaac acgtgttttg tcctcatcca
     2461 aaacagcctt gacagcttga gcttctgcta atatttcagc ttgagctttt tcttcagctt
     2521 tttgttttcc ttttaattca ccgatgcttt gactagttgc ttctttagct aaatttttct
     2581 taataaggaa attttgagca tagcctgttg ggacctcttt gatttctcct tttttacctt
     2641 ttccttttac atctgctaaa aaaataactt tcatgattct acttctcctg tttctttcat
     2701 tgtcatatta atagttttca ataataagta cttcgcttgg ggaagactga tatccgttaa
     2761 ctgacaggca gcaagattaa agtggcctcc tccacctaat ttttccatca cacgttgaac
     2821 attgatttta ctacgacttc tagctgaaat agcaatctta tgagaagctg tttcaactaa
     2881 tacaaagcta gcctcaacgt gagccattga cagtatcgta tctgcagctt tactagcaat
     2941 aacattgcta taaagatgat ttttttctcc tgcagctaca atgatactgt caccaagacg
     3001 ttctccttgt aaaataattt catttatttg cttatattct tcaaaatctg ttgcggatat
     3061 attttgaatt tcaacactat cacttccttt gcttcttaag taactagcga catcaaaggt
     3121 acgacttgtc actcgcgtag aaaaattttt agtatcaagc ataatacctg ccattaaaac
     3181 actggcttgg atcttattta aacatttttt agcattttga aattgaatta actcagtgac
     3241 gagctccgca gcactacttg ctccactttc aataaaagtt aagatagcat tatcaggaaa
     3301 atcatcatct cttctgtgat gatcaactac aataacattt tgaaactgtt cataaaattc
     3361 tttagaaagt gttaaagata tcttagaatg gtcaaccatt actaaaagtg atcttggagt
     3421 cactaaaccc attgcttgag aaacactgat tagacgagtc tttccgtcag cctgcaatcg
     3481 ctcaatagcc ctttcaatat ctggactcat ctcatctgga ttgtaaacgg caaaactatt
     3541 ttcaataatg ttacctgcga aaaattgcat accaacagct gaacctagtg catccatatc
     3601 aagtttccta tgtccaacaa taaaaacatt gtccaccatc ttgattcgat ctgaaatagc
     3661 tgtcatcata gcacgggtac gtgttcttga acgtttaact gtagaaacag accctccccc
     3721 gaaataaatt ggattcgtat gatccgcatt ttcacgaatg acaatctgat caccaccacg
     3781 aacaagcgca atattaagat tctcaagagc tacctgtcca atctggctat gattttcttc
     3841 accaaaagaa attcctatgc tgagtgttaa agggcgctga gcatcttgag cttctttacg
     3901 aaactcttct aagacagaaa atttattatc catcaaatca tttaatgttt taaagtctgt
     3961 aaagaaatag tagcgatcca tattaacacg acggtaaaaa atccgttttg actccataaa
     4021 ctcatcaatg aagttagcta caaatgaatt aatttttgag gtatctgcat ctgataaatc
     4081 atcagtgata tcatcataat tatcaaccga aataatgcca acaaccggtc ttaacatact
     4141 agcatcagct aattgcctgt ttcccacaaa gctatcaaaa aaataaaaaa ttcctgatga
     4201 tacatcaata taagaagtgt atttattacc agaaacttca aatgtttgag aaatatcttc
     4261 acgacgtttt tccgtaataa tttgctgaat caaaccgttt tgtataaaac cctcttcagt
     4321 tgtaaaaatt aattctgcat aaggattata ccattctaca gcgttggtct cttgatcaaa
     4381 ttgaactact ccaacaggca tattatcaag tagcgttttt aggttatctt ctgtttgttc
     4441 atttaagagc tcaatatgag ctaagtctga taattgataa gcttcttttt gataccataa
     4501 aagagcaaca acaaatagca aaacgagaaa aatagctaat aatattaata tttttgattg
     4561 cataatactg acacaaagtg ccagcagtcc aaataaaatc aatcccatca taatcaaatg
     4621 aatggtttca aaacgaaatt ttttcatctt tataacctct taagcacaca ttataccata
     4681 aaaaagccct gaaatacaga gcttccactt gctttgagat tacaatttca tttccattta
     4741 atattttcga tgagcttttc cgtttccttc taaataaatc atcaagatac tgatgtccgc
     4801 aggattgact cctgaaatac gactagcttg tccaattgtt tcaggattaa ttttcttaaa
     4861 tttctgacgc gcctcagttg caatagaatc aatagcatcc caatcaatat ttgtaggaat
     4921 acgtttttct tccatgcgtt tcatcttagc aacctgatct aaagctttgc gaatatagcc
     4981 ttcgtacttg atttctgttt ctaaaagttc aatgatttta gcatctaaat cttcagccgc
     5041 aggaccaaca aaagagactg cagtcgcata atcaatttct ggacgacgca tgaattcttt
     5101 agcagtcatc gcatcggtta acggtttgaa gcctagatct tgaacgcggt cattggtttc
     5161 tttaatcggt tttaatttga tactgttcag acgttttaat tcgttatcaa attggttttt
     5221 cttaatttcg aaggccttcc aacgctcatc atcaaccaac ccaatgtcgc gaccaatctc
     5281 tgtcaaacgc atatcagcgt tgtcatgacg taaaatcaaa cgatactcag ctcgcgatgt
     5341 caacaagcga taaggttcca aggttccttt ggtaaccaaa tcgtcaatca taacgccaat
     5401 ataggcatcg ctccgtttca aaataagttc tggcttacct tgaactttca aagcagcatt
     5461 gattccagca ataagtcctt ggccagcagc ctcttcatac ccagaagttc cattagtttg
     5521 cccagccgta aagagtcctg aaattagctt ggtttcaagt gtggcacgta gctggtgagg
     5581 taaaacaata tcatattcaa tagcataacc agtgcgcatc atttcagcct tttcaagtcc
     5641 tttgatcgaa tgaatcaaat ctttttggac atcttctgga agactcgttg acaacccttg
     5701 aacatacact tcttctgtat cacgcccctc tggctctaag aaaagttgat gacgttcttt
     5761 atcagcaaag cgaacaatct tatcttcaat agatgggcag taacgagggc ctacaccttt
     5821 aacaatgcca gaaaacatcg gtgctctgta aaggttctga ttaatgatat catgactagt
     5881 ttgattcgta taagtcaacc agcagggaat ttgatctttg agataatcag catcttttga
     5941 cataaatgaa aaatgattag gtttgtcatc acctggctga atttccgttt gatcgtaatt
     6001 aatagaagat gctttgacac gaggaggcgt tcctgttttg aatctgccaa tttctaagcc
     6061 gagttttttt aaattatctg ctaaggttac tgatgccaaa ctattattag gcccagaaga
     6121 atatttgagt tctcctaaaa taatttcgcc acgcagagct gttcctgttg tcactacaac
     6181 tgccttagct gcaaattttt gtcctgtggc tgttaaaaca cctacaactc gtccatcttc
     6241 aactagaata tcatcaatca tcgtttggcg aagagtcaaa ttagcctgtt tttcaaccgt
     6301 atgtttcatt tcacgcgcat acagggattt atctgcttga gctcggagag cgcgtacagc
     6361 tggtccctta cctgtattaa gcattttcat ctggatataa gttttatcaa tatttttacc
     6421 catttcgccg ccaagagcat caatctctct aaccactatc cctttggcag atcctccaat
     6481 agaaggatta cacggcataa aagccaacat atcaaggttg attgttgcca ataaagtttt
     6541 acaacccata cgactagtgg ccaaactggc ttcaacacca gcatgacctg cacctatgac
     6601 aatgacgtca tagctttctg taaattcatg tgtcattttt ttaaaatcct ttatttcagt
     6661 ctattcattt aaaatcatac gctttagttt agccttcaat acggacaata tgtcctggcc
     6721 atttagccaa ctcggtttgt aaaaactcag gaacaagatt catttgatcc agttgattga
     6781 ttggaatcca ttcacaaacc tgtcgcttgc attctctatc atttctagtt tagggtcttc
     6841 taaggggctt accaaataat gaaattcaat attatgccag aaaacatcat cgatatcaaa
     6901 atgattctca accataaaag ccagttgatt aaccttagct cgaataccaa cttcctctaa
     6961 ggtttcacgt aaaacagttt catgcgtttt ttcacctacc aaacttgtac caccaatggt
     7021 gtaatattgg tcatctgcat ctctagttaa aaaattctta ccatttctaa caatcaagca
     7081 ctagctcgta aactaaagtt atctgacctc tagtgattct aaattccagt cctattagcc
     7141 atctcatttc tagagctaaa ccataaaaag ggccaaaacc ctagaagatt gcaggacaaa
     7201 aaaacctaca actttcatga gctttgacca tcattccggt tgttactatc tattttaaaa
     7261 aaaatgatta gtgattgtca atattgattt catcacagac ctttacagta atgtcaatgt
     7321 ttttacaact ctgtcaatct attgtaatgt ttttaaaatg attacaaaag tatcactatg
     7381 tctaatctag cgaggcgaga aataaaaatg tcatcagtat tatcatacga ttttttgata
     7441 tcttcta
//
LOCUS       DAUGQX010000061         7401 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUGQX010000061 DAUGQX010000000
VERSION     DAUGQX010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7401
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.061"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(154..309)
                     /locus_tag="VIA51_001599"
     CDS             complement(154..309)
                     /locus_tag="VIA51_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEQ8683535.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(812..2218)
                     /gene="lacG"
                     /locus_tag="VIA51_001600"
     CDS             complement(812..2218)
                     /gene="lacG"
                     /locus_tag="VIA51_001600"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEQ8683536.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDG
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(2306..4003)
                     /locus_tag="VIA51_001601"
     CDS             complement(2306..4003)
                     /locus_tag="VIA51_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8683537.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKACVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHTTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKAQFEN"
     gene            complement(4003..4320)
                     /locus_tag="VIA51_001602"
     CDS             complement(4003..4320)
                     /locus_tag="VIA51_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8683538.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(4344..5327)
                     /gene="lacD"
                     /locus_tag="VIA51_001603"
     CDS             complement(4344..5327)
                     /gene="lacD"
                     /locus_tag="VIA51_001603"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8683539.1"
                     /translation="MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEG
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(5331..6260)
                     /locus_tag="VIA51_001604"
     CDS             complement(5331..6260)
                     /locus_tag="VIA51_001604"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEQ8683540.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNEFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            complement(6308..6823)
                     /gene="lacB"
                     /locus_tag="VIA51_001605"
     CDS             complement(6308..6823)
                     /gene="lacB"
                     /locus_tag="VIA51_001605"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8683541.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(6858..7286)
                     /gene="lacA"
                     /locus_tag="VIA51_001606"
     CDS             complement(6858..7286)
                     /gene="lacA"
                     /locus_tag="VIA51_001606"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8683542.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTT
                     LAVVKEVNASDDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
BASE COUNT         2296 a         1503 c         1192 g         2410 t
ORIGIN      
        1 aaaattgagt taaagtattc gtaaaactga tgttgctgat actctaactt taattcattt
       61 ctttttatca ttttttccta ccactactta aaaatcctgc ctagactgag tctaaacagg
      121 aaatttttag tctgcttgtc cagattgttt taattaacaa caaacaaata ctgagttcgg
      181 acagtcatca gtaatagttg caaaccaacc ggaacctttt ttaccaccag ctacttccat
      241 aagttctttt tcagaaactt cttcgatagc attagtcaaa atatcctttg aatttttcat
      301 aaaactcatt ctcctttcta tcagtatgta gtgactattt tctacacttt tattgtaaat
      361 aatacgtctt cattttcaat gagtaaaaag tgcaaaaatg acttttttca tattttttag
      421 taagattttt gagatgtcac ataagaggtc actttataac aaatagccct ctgatataaa
      481 aaacaaaact cgttctttac agctatttta caatctaatc gcttctcgtt ataacatcaa
      541 tctctaatca gaaaatggtt actttactta tttaatcagg tcaggagttt gaatgacaga
      601 agtcaaatat ctgaaaaagg atgttaaata aaactttcaa aacccatttt catcaactaa
      661 aaacacttat aacccgatct tacaactaat ggattaccat caacagcaaa taatactatg
      721 cttgaaaaat gtcaacatca tctacttttt gtgactataa ttcagtaaac gaacatgacg
      781 tgtaaaaatg tattaaagaa gtatctcaaa atcattcaat cacttgagtt tctgctactt
      841 ttttatacca gtaggcactc ttcttaggat aacgttcttg agtttcaaaa tcaacataga
      901 agagaccgta acgtttttca tagccatttg accatgaaaa gacatccatc agtgaccaca
      961 taaagtatcc tttaacattt gcaccatcag aaatagcatc agaaataact tctaagtgtt
     1021 ttttcacata atcgatacgt ccaccatcat agacagtatt atctacaaac tcatctttgt
     1081 agccaagacc attctctgta atgtaaattt tcttgtaatt aggataatcg gctttgacac
     1141 gcatgatttg atcatataag ccttgtggga agataatcca gtcccagtcc gtttttggaa
     1201 catcaacggg tgcttttctt cgaccaacac ccttgatttg gtatttagag ctgccttttt
     1261 cacccttgcc attgtgaatg atttcagtct caccatcaaa agcttgcatc caatcactca
     1321 tatagtagtt aataccaagg aaatcattca aatcttttgc ggcgtctagt gcggcaaaat
     1381 cttcttcgcg aagatcaagt tcaccgccat tcacctcaag gatatggtta acaccttcca
     1441 ttgttttatc tgaatactta ccaagataag tagcatcaag gataaattta ttatggatga
     1501 tatcttcaag ttcagctgct ctaacatcat caggattgtt agcgtcaaat ggatacttag
     1561 ttggaagtgc atggacaaca ccaatttcac ctgaataacc actatcttta aagagtttga
     1621 ctgcacgagc atgagagacc atcatgttat ggtgtgattg gaaaacttta gcaagatcat
     1681 attggatacc tggagggaat ttaccaacta agtattggcc atcaccaata ggcccaattt
     1741 cgttaaatgt tgtccaatag ttaacttctg agaattcttt aaaacaaaat tctgcataat
     1801 ttacaaaatg ttcaatgttc tcacgattga ggaagtcacc atccgagtgg agagcttctg
     1861 gggtatcaaa atggtgaagt gtaacaaaag gctcaacatg acgcttatga cactctgcaa
     1921 aaagattgtg gtagtattct actcctttag ggttaacttc tccttttcct gttggaaaaa
     1981 tacgagacca ggcaatagag atacggatgc cgttgacacc aaattcttca ctaagtttca
     2041 aatcgacagg gtaacgatta taaaaatcac ttgctggctc agctgtgtac caatagttgt
     2101 cttctaagta tttatcccaa gctactggtc ctttaccatc tgtgtgggta gcgccttcag
     2161 cctggtaagc agctgtagca ccaccaaaaa taaaatcttt aggtaatgtt ttagtcatct
     2221 cagtttctcc ttgaatatct ttcaaaaata aagttcccaa aacaattttt gtgtttgaga
     2281 actttacgac atttaaactg ttttcttaat tttcaaactg tgcttttaca aaatcaagag
     2341 ctccttgacc atcacgggtc aatttgatgt attgagcccc ttctgtttta gctaatttaa
     2401 tatcaagttt atcagtttcc actttcatat cttcatagtt agaagctact tgaggtgcaa
     2461 ggataacaag ttgatattgt ggtaaaatct cacggtgagc accataactt cctgctgctg
     2521 cagtgacagg tgcaccatat tctttagctg ctttattcaa agcatttgca agcaaaccac
     2581 ttgtaccacc accggcacaa agaacgagaa cattagtttg atcagtgatt tctttggttt
     2641 ctttagctgc tgatttttca agaatagcat cagctttttt agtatcaaag tttgctgcta
     2701 ctttttcttt gagggcatct gatgaattcg tacctgctgc ttcttcagca agaatttgct
     2761 catcatatac tttcaagaat gggtagtaga tgatcacatc aacgacaatt aacaaagctg
     2821 ccaaaatgaa tgctagaact tggaagtttg taccaagaat gagacctaat ggagctggtg
     2881 tagtccaagg taagtttgca gtgaaactgt tcattccaag tgtgtcaatg aagaatttga
     2941 aaatccatac gttgacaatc ggtgccaaga taaatggaat aaagaaaatt gggttcaaaa
     3001 caagtggagc accaaacaaa atgggttcgt taacaccaaa gaatgttgga acaactgatg
     3061 cacgtccaat ggctttgtta cgttttgatt ttgttaacca catgaacatg aatggaacga
     3121 cgagagttgc accagtacca cccatggtaa cgatgaacat ttgagtccct gaagtcaaaa
     3181 tcttgtcagc atgttcacca gcttgaagta attgaaggtt ggtttcagca tttgcgtaag
     3241 taatcgctgc aatggctggt tcaacaatag atggtccatg aataccaaca aaccagaaga
     3301 aagcaaatgc accgaagata atagtgattc caacataacc atctgctgct tggaacaatg
     3361 gtgcaagaag tttaccaatt gactcggcaa cgttaacgcc taaagtagta tgaacaatca
     3421 attcaatcac ataaagaagt acaactgata atgtaaatgg aatcaaatct ttaaaaactt
     3481 gagatatatt tggtggcacc tcttctggca tgcgaatagt aacattgttt ttcacacagg
     3541 ctttatagac atttacggta ataaaagctg cgatgaaggc cgttaacaaa ccttttgttc
     3601 ccataaatcc agttaagaaa ccaccgtctt ttgctggatt tgctgccata agtaaaaaac
     3661 ctacaatagc agcaagcatg gttgaaataa agttgatttg gttagtgcta ggcaatgagc
     3721 ggttcattga atcggttaat gcttttgcag tcgtaccagc cacaaacaaa cctaaaatac
     3781 ccattgagta gttgtatggc gtcatcaaga gattctcaat atccttactc caatggaagc
     3841 cccatgcatt tggaacatag gcaatcaaga taaagatact tgaaaacaag ataacaggca
     3901 taccagcgat aaaaccatca cgaatagcgc gaagatagat gtttcgagaa attttctcga
     3961 agaaaggttt ccctttctca atctgagcaa ttaatccatt cattattttg ctcctctctt
     4021 ataaagttca atcatgtgtt tcattaaatc ttgtaataaa atggtcgtca ttaaatgatc
     4081 ttgaccatgc attaaagtga cactataagc taagtcatct ccagctgctt ctttttgtag
     4141 tagacttgtc tgagcattgt gagcatcatt caagcagtca ctacctgcag cgattaattc
     4201 ttctgcttta gcataatctc cttcttgcgc tgctttaagc gcttccaaaa attttgaacg
     4261 ggcatcacca gcataggcta cgatttcaaa acctaaaaga gtagtttctt ctctattcat
     4321 tgtagtttcc tccgaaaata atgttacatt ttttcagtcc aaggacttgc agttttatct
     4381 agtactttgt ttaattcgtc aatattttta aaaccttctg tacgcaacca ttcacgagct
     4441 gcttgtggtc cttcttcgat atagactttt acagatcctg cccaggtagc acgtccacat
     4501 aagacaccgt tgaatttagc acctgattct gctgcaaaca ccaaagtatc ttggaacaat
     4561 ttggcagaaa caccagcact caaataaatg tatggtaaat cagtagaagc ttcttggtca
     4621 cggaaagctt gagctgcttc ttcttttgta aagagaacct caccatctgc aaagccttct
     4681 acaaatttca tatttactgg aacttcaact ttcaacacgt caactccaaa gcgctctttt
     4741 gagaaaactt tcattgcttc gttaacttta tgagctttaa cttttgcaaa ctcagggctt
     4801 gcattgtcag caattttctc atcataagtt agaatttcta agtagaatgg aatatcttct
     4861 gcacggcatt cagaaccaat acgttcaatg taagcttttt tctgctcgtt aacatcttga
     4921 tctccatcaa tatcatagta aagaaggaat ttaactgctt ctgctccagc ttctttaata
     4981 cgttttgcag accaaacatc taaacaatca ggtaagcgac tagttgttgt tgcatcgtat
     5041 cctgttttct catatgccaa caacaagcct gcttcttctg aacgaacacg acttgctggc
     5101 aagccatatt caggatcaag tagaattgag gatgcaaatg gtgttagttc ttcagaaact
     5161 aaacttttaa gctcttcaat ttgttctact gttggctctt ttgtttgatg ttgagccatc
     5221 atacgtttga gagctccacg ttggtcaaaa gctaaggcag aaataacacc atctacactt
     5281 agtttttcca tgcttttgcg tttgttttca gttaaagtaa ttgtcatttt ttatacctct
     5341 ttgactttaa tagattgata taacttatcg taatttgcca tgttaacatg cccagttgtt
     5401 ttttcttgcg catttaacat ccctaagaca tttgcttttg ttaataaagc tcgatcatct
     5461 tcatcattcg ctaaacctga agcaatacct gccactgtag aatcccctga acctacagcg
     5521 cttacaattt tgattttagg aatgtcaacg ttataaaacg tatccttgtg ctttgcaaat
     5581 acaccatcag caccaagaga aacgattatc cattcaattc catcaaatag ttcatcttgt
     5641 aagacttctt ttaaggcatc aaaatctttt gtcatttctt tacctagaag ttgagaaagt
     5701 tcttcaagat taggtttgat aactgttggt ttactatcac cttttagtac tgcttctaga
     5761 gcatttccag aacaatccag aaccgttttc ttaccattaa gattggcaat cttgattaac
     5821 ttctgatagt aatcatctgg cataccagca ggcaaactgc ctgagagcgt cactacgtca
     5881 acatcattca gtaaatactt aaaatgatga gtaaatccat caatttcatc tacacttaac
     5941 atcggtcctt tttctaaaat ctccgtttga ttaccttcgt gtaaaatggc tatacaagtt
     6001 ctagtatcac ctgaaatttt atagaagcga cttaaaatcg aatcaggaag atgattaatg
     6061 ataaaatcac cgctttctcc acctacacaa cctgtagctt tgactgtctc accgaattca
     6121 ttaagaactc gggaaacatt caagccttta ccaccgggtg tctttgtaac gtctacaact
     6181 cgattgacag tatcgcattt tagctcatcc aaagggtagg agacatcaat agctggattt
     6241 aaagtaactg ttaaaatcac aatagctcct ttttctatat atatccctat agtaatttat
     6301 tcaaatatta gtcgtgatat tcaccacggt cccatttttc taggaattca tcaaagaagt
     6361 gtgggttgtt ttgatcttgg ctagcatgtt gcaagctatc cattttttca atccattttt
     6421 tattttcttc agttggtttg tattccgcgg ccaagaaagc atcgataata tcattcatca
     6481 ataaaccacc gataattttt ccaccaaaac caataacgtt tgcgtttagc tcttcttttg
     6541 agtagatagc agatgtcata tctctaacga gtgctgaacg aattccagga actttgttta
     6601 cagcatttgt gataccaaca ccagtaccac agataacaac acctagttct gcttcaccac
     6661 ttgctactgc ttcaccaact tttttaccaa aaattggata gtgtgtgcga acattatcat
     6721 acgtaccaca atcaataact ttatgacctt gtgattttag gtaatccaca acagcgattt
     6781 tttcataagt aacaatatgg tcacaaccta cagcaatttt catttttgtt ctccttgttt
     6841 taacctattt caatcaatta gcacatttta ttaagcatgt cgacacgaac ttgatgacgt
     6901 ccaccatcat atttaccttc gacaaagcct ttgataatgt tctttgcaat tcctggagca
     6961 ctaatttcag aaccaagcgt gatgattcga gcattgttgt gtcctcttgt catgtatgct
     7021 gagcgctcat ctgatacttc agctgccacc attcctttga ttttagtagc taccatgaaa
     7081 gaaccaacac catatgcatc aatgacaata cctaagttat catcggatgc attaacttct
     7141 tttacaacag ctaaagttgt atctacaaag tcacgtactt cgttttcact aacatcaacg
     7201 acttcgtatt taccttcttt aaggtaatct ttgataactt ctttaagttc ttgacctgct
     7261 ttgtcagcac cgataataat tgccatttta tttctcctat gatttagaat aagtaaatgt
     7321 ggaaaaccta cgtagatagt taattaacga tttgcaacat cttttgaaat aacgctttca
     7381 ttatttctat gacctaatca t
//
LOCUS       DAUGQX010000062         7117 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUGQX010000062 DAUGQX010000000
VERSION     DAUGQX010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7117
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.062"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(82..270)
                     /locus_tag="VIA51_001607"
     CDS             complement(82..270)
                     /locus_tag="VIA51_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEQ8683543.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(652..1533)
                     /locus_tag="VIA51_001608"
     CDS             complement(652..1533)
                     /locus_tag="VIA51_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEQ8683544.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            complement(1740..1825)
                     /locus_tag="VIA51_001609"
     tRNA            complement(1740..1825)
                     /locus_tag="VIA51_001609"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1789..1791),aa:Leu,seq:aag)
     gene            complement(1879..2805)
                     /locus_tag="VIA51_001610"
     CDS             complement(1879..2805)
                     /locus_tag="VIA51_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8683545.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYASVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            complement(2973..4577)
                     /locus_tag="VIA51_001611"
     CDS             complement(2973..4577)
                     /locus_tag="VIA51_001611"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEQ8683546.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            complement(4834..5409)
                     /locus_tag="VIA51_001612"
     CDS             complement(4834..5409)
                     /locus_tag="VIA51_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEQ8683547.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            complement(5626..6909)
                     /locus_tag="VIA51_001613"
     CDS             complement(5626..6909)
                     /locus_tag="VIA51_001613"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEQ8683548.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
BASE COUNT         2067 a         1532 c         1150 g         2368 t
ORIGIN      
        1 tagctaacga tagcgtttat taccttgact agcttatgga tagaaataag ctaataaaaa
       61 aagccctaag gcttatttct attagatgcg ttctacttta ccagatttaa gcgcacgagc
      121 agaagcccaa acttttttag gtttaccatc aacaaggata gtaacttttt gaaggtttgg
      181 tttaactgta cgttttgttt ggttcatcgc gtgtgaacgg ttgtttccag aaacggtttt
      241 acgtcctgta aaataacata ctttagccat tttgatctat ttcctcctac gtagaatatg
      301 tttacggatg tgctagcacc acatacctat ctattctatc atagggtgct taatttgaca
      361 aggtatttcc cattttcttt ttcaacaatt ttacggaatt actattacaa tagtctacgt
      421 actcattttt cactacattt tttagctaaa acatattaac attacgctta acctctttaa
      481 caataacaaa aagacttacc atagatagca gggtccagat tttaatactc taaattatgc
      541 tttgtttgtt cacaatcaaa gattatttca cagaaactgg tatccatttt agggtgtcaa
      601 ttatatctaa aaaagccctc aagagggctt tagggtgttt aatactctaa attatgcttt
      661 gttagctgat ccgaaaacat cgatacgttc ttcaacagca ccttgaacag ctttcatacc
      721 tggagccaag aatttacgtg ggtcaaataa ttttttacca tcatattctg cttcgttagc
      781 ttcgtagtta cgagcaaatt cacgagttgc gttagagaaa gcgatttgac tttcagtgtt
      841 aacattaact ttagcaacac caagacggat tgcttctttg atttgatcgt caggaatacc
      901 agaaccaccg tgcaatacga ttgggaaacc tggtacagct gctgttaatt tttctaagtg
      961 gtcaagagca agaccttccc agttttctgg gtatggaccg tggatgttac cgataccagc
     1021 tgccaagaag tcaattccag tttcaaccat tgctttagca tcttcgattg gagcgagctc
     1081 acctttaccg atgataccgt cttcttcacc accgattgta ccaacttcag cttcaactga
     1141 aacgccttta gcatgtgcaa ttttaacaac ttctgcagtt ttagcaaggt tttcttcaac
     1201 tggaaggtgt gaaccgtcaa acatgattga agtgtaacct acttcgatac actcaagagc
     1261 atcttcgtag tgaccatgat caaggtggat agcaacagga acagtgatac ccattgactc
     1321 aacaaggtta gtaataagag attgacatac tttataacca cccatgtatt ttgctgcacc
     1381 cattgatgtt tggataagaa ctggagcttg tttagcttct gctgcacgca agattgcttg
     1441 agtccactct aagttgtttg tgttaaatcc accaacagca tatccgtttt cacgagctgc
     1501 ttggacaaat ttttctgctg aaacgattgc catttgtaag gcctcctctt atttttcggg
     1561 ataactcccc gtttacattg ttcattctag cacaattttc cataaatttc tagcctttca
     1621 caagcttaaa gcgttttcca aaagcagatt atcaaaagtt ttctccagta aatctatgcc
     1681 ttcttatcct tcatttaacc aaaaaaaaga gacgaatcaa tgattcacct cttacattat
     1741 gcggagagtg ggacttgaac ccacacgacc taaagcggtc acaggatcct tagtcctgcg
     1801 cgtctgccaa ttccgccatc cccgctactc atcagtaaca taaattatta tagcaactgt
     1861 gagtttaact gtcaatactt atttctcaac ttttttcaaa aaagcggcaa tttttttctg
     1921 gtattgttct gggtttgttt caaaggattt ggcgtgtttt gcccctttaa caatcaagat
     1981 ttccttagga cctttcgtgg ccttataatt gtcataaacc atttttgtag gaacaaaatc
     2041 atccttatca ccgtggataa ataaagttgg acgtttattt ttagccagct gtttcactga
     2101 gctcgcttct ccgtaactaa aacctgctcg aatcttagat aaggcagaga cttcatagag
     2161 taaaggaaag gcaggcaagt tgtacatagc cttggcctga aacttcaatt cgtcccaaac
     2221 actggcataa ccgcaatctt cgatgaggga ggtgacttgc gcaggcaatc gctcaccact
     2281 tgccatcatt actgttgcag cacccataga taagccaaag agtgtgattt ggctttcagg
     2341 gttttcctta atcagttggt ctgtccaagc catgacatta aggcggtcat tccagccata
     2401 accaatcaag ttcccttcac tttccccatg ggcctcattg tctggcatta agacattata
     2461 gcccaaatca tgaaaaagca tggcatatgg cttcatatct tctttgtcat tcgtaaaacc
     2521 atgaacaaca atagctgtct tttttgtttt ttgagcagct ggtaagtacc accccacttg
     2581 ttttaaccca cgatttgtta gttgacgttt ttcgtaaggt aaagcgtcaa aagactgttc
     2641 agctgggtat aatggattat ttgtactccg tttcttatta ttaataaacg atttctcttc
     2701 tcttatttgt gcaacatgaa agaaataaaa actagcacct acgctaataa gagttatcaa
     2761 aaggaataga attcctaaat actttgctat tcgaatagtt ttcataccaa gtattttaca
     2821 aaaaaatgac tgaaaaagaa agtgctaacc taaaaatatc acgtttttct ttttctaatg
     2881 ctatttttat agaaaagatc cctttaatag ctagtaatct ttatcagtat ctgccagcca
     2941 agtagaatgc cacaaactta cccttaaaac cactaattgc tatttttaat agcagctgta
     3001 acaaaagcgg tgtatagctc ctcaggacga tttggacggc tttgcaattc tgggtggtat
     3061 tgagctgcta caaagaattt tttctctttc aattctacaa tttcaactaa gcggttgtca
     3121 ggtgataccc ctgagaaaac aaaaccagct gcttcaaatt ctggacggaa tttgttgttg
     3181 aactcataac ggtgacgatg acgacgttgc accacctctt gattattgta agccattgct
     3241 gcttttgaac ctggtttcaa tttacatggg tacaatccca gacgaagcgt acctcccata
     3301 tcttcaatat caatttgatc acgcatgata tcaatgatgg ggtatttagt acttggctct
     3361 aattcaaaag agtttgcacc ttccatattg aggacatggc gggcaaattc aacacaagtc
     3421 aactgcatgc caagacaaat accaagcatt ggcacatcat tttcgcgggc atagcgaatc
     3481 gcttggatct tgccttctgt accacgttga ccaaaaccac ctggtacaat aatcccatcc
     3541 gcatctccca acaagtcagc tgcattatcc accgtcacat cgttagcatt gacccatttt
     3601 aggtcaattg cggtatcatt ggcataacca gaatgtttca aggcttccac aacagataag
     3661 taggcatctg gcaattccac atatttacca accaaggcaa tttttgttgt ttttcttaaa
     3721 ttcatcacct tgtcaaccat agctgaccac tcggtcatat cagcttgtgg cgcattcaat
     3781 ttcaaatgat cacaaacaat ctgatccatt gattgagctt gcaagttcaa tggaatttga
     3841 tacaagtgtt ctacatcacg tgactcgata acagcttctg aattcacatc acagaactga
     3901 gccaatttat ttttaatccc ctgctcaact ggctcttccg tacgaataac caacatattc
     3961 ggttgaatcc ctaaaccacg caattcttta acggaatgtt gcgttggctt agttttcatt
     4021 tcacccgctg cctttaaata tggcaacaag gtggtgtgaa tatacatcac attttcagaa
     4081 ccaacatcag ctttcatctg acgaagagct tctaagaacg gtaaactttc aatatcgcca
     4141 acagtccccc cgacctcagt aataattaca tcagagtccg ttgttgaagc tgcgcgtttg
     4201 attttttctt taagggcatc tgtgatatga ggaatcacct gaacagtcgc tccaaggtac
     4261 tcgcctttac gttctttacg aaggacttca ctataaattt tacctgttgt aacattggaa
     4321 tatttattaa gattgatatc aataaaacgt tcatagtgac ccaaatccaa gtcggtttca
     4381 gcaccgtcat ctgtcacata tacttctcca tgctgatagg ggctcatcgt ccctggatca
     4441 atattaatat aaggatcaaa tttttgaatc gtcaccttaa gtccacgatt ttttaacaat
     4501 cggccaagac ttgccgcaac aattcctttg ccaattgatg atacaacacc accagttaca
     4561 aaaatgtatt tcgtcatagt actcctttat ataagctgaa taaaagcatt gctttcttgt
     4621 taattcccta ttagttggtt ccacattggt taggtatcac cttagttttc taaatataga
     4681 ggcaaactgg cattattcta gaaaacaaaa atagccccct attaactaga gagcttttgc
     4741 ctgacctcat aaagaggtgc ccgaataata atataaacta taatagacaa tttgtcaaat
     4801 gataattaca tttttatttc tgaactaaag acattagaga actggctctt catcttcttc
     4861 atcttcttcg tcttcttcat tgatatcaac ttcttcaaaa tcatcttcag ggataatttc
     4921 attcaattct gaatcatatg actccacttc tgatttttca tcatctggat cttcttcatc
     4981 atattcaacc tcagctgatt cttctgtgaa atcttcatct tctggatcat catctctata
     5041 atcaatagcg tcttcatctc catccatgaa agcattaacg cgttttttct tacgtttttg
     5101 tgcgccatct tcatcttctt ctagagtaat aatttcttca tcaatttcat caatagcata
     5161 ccacgaacga agtccccatt tgttttcacc tagaggaata aatgagccat ccgtatttaa
     5221 gtcagtatag aaaaatggta atgcatgacg aatacctgca tcagattttc ctaagtaatt
     5281 ttgaatctca ttgactaaat cgctaaagta catctcattg tcgcgaccgc gttcttccaa
     5341 aatggcacgc gccacttcaa tcatggaaag ctcgcttttt tcttgtcctg caaatacgtc
     5401 taatttcaag gcagttctcc ttattttatc attctctacc attttacgct aaaaaaagta
     5461 attcgtcaaa acttttatca actcatatca cttcttcttg acaaatcttt aaagctaatt
     5521 cattaaaata acgtttaact aattccttat tatttcttta gaaaaagaaa aaccagacta
     5581 gaaagacgtt ctaatccggc ttgtacgttt tgttccttaa taagattact taacgcttgc
     5641 tgtgcttgta atcacttcaa ctgctttttt cattgcaata tcatgtttca acatatctgc
     5701 tgaaagaaga gaacgaactt ggtcagctgg catgttatat tctgttgcaa ggtcattaat
     5761 ttcttgttca atttcactat ctgttgcttc aaaaccttct gctttagcaa ttgcttcaat
     5821 aacaaggttt gttttaacac gtttgtcagc ttcagctgaa tattggttat gtaaatcttc
     5881 ttgagttgta ccagtcaatt ggaagtacat ttcaggtgag attccttgac gttgcatgtt
     5941 gcccataaat tcattcactg aacggttgac ttcttcatga atcatttctt cgggtaaatc
     6001 aacaatttca gcatttgcaa ctgctaattc aatcgcagct ccttcaacag catcatcata
     6061 agcagtttct tgagctgctt caagttcttt acgatatttt acttttaagt cttcaagtgt
     6121 gtcaacatct tcatcaatat cttttgcaag ctcatcatca agctctggta cttcttttgt
     6181 tttgacttcg tgaatagttg tcataaattt agcggcttta cctgcaagat cttctgcttg
     6241 gtaagattct gggaatgtga cattaacttc tacttcatcg ccagctttag caccaactag
     6301 ttgatcttca aaacctggga taaattgtcc tgaaccaagt tcaagagaga agttatctcc
     6361 tttaccgcca tcaaactcaa caccatcaac tgaaccaaca aagtcaatca caacagtgtc
     6421 accttgagct gcttcaccgt ctttaataat gagttccgca aggttttgac gttcgcgctc
     6481 aattttagca tccacgtctt catctgaaac ttcttttgaa gcatcaactt ctacaactag
     6541 gtttttgtaa tcaccaagtt tcacttcagg ttttgtcaca acttcagcag aaagtgtcca
     6601 ctctttccct ttttccattg acacaacatc gatttttggt tgtgcaacca catcaagacc
     6661 aagttccgtc acagctgctt cataagcttc tggcaataca atattcaaag catcttcata
     6721 aagaacttct tcaccaaatt tttgattgaa gactggacga ggcatgtgtc ctttacggaa
     6781 acctggtgca ttcaagtctt ttttgatttt attaaaagct ttatcaagag ctggttttat
     6841 tttatcttga ctgattgtaa atgtaatcac gccacgattt gtagctttgt tttcaaatga
     6901 tgtagacatt aagtcatttc tccttaaaat aatttcgata cagttcattt tatcataatt
     6961 taaagcgttt ttaaagcttt ttatgcgtga aatcaaacgc gctattaaga gtatctacct
     7021 gtcattagtc tactaacagt tattttcaat ttataaaggt taatgttaga ctttttcgct
     7081 tactaactga ctattttcaa gcattatcac aacggat
//
LOCUS       DAUGQX010000063         6990 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUGQX010000063 DAUGQX010000000
VERSION     DAUGQX010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6990
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.063"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(159..2477)
                     /gene="pcrA"
                     /locus_tag="VIA51_001614"
     CDS             complement(159..2477)
                     /gene="pcrA"
                     /locus_tag="VIA51_001614"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEQ8683549.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
     regulatory      2792..2878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            3006..4328
                     /locus_tag="VIA51_001615"
     CDS             3006..4328
                     /locus_tag="VIA51_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEQ8683550.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSHLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     gene            4448..5683
                     /locus_tag="VIA51_001616"
     CDS             4448..5683
                     /locus_tag="VIA51_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEQ8683551.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQ
                     ITPIAKKQLHHTHYRIVKM"
     gene            complement(6052..6825)
                     /gene="cfa"
                     /locus_tag="VIA51_001617"
     CDS             complement(6052..6825)
                     /gene="cfa"
                     /locus_tag="VIA51_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEQ8683552.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NFQRDALVQKLDEGHQQLEAIKHEAKGTDIETTVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQDALETALKS"
BASE COUNT         1982 a         1365 c         1290 g         2353 t
ORIGIN      
        1 cactcgttat ttaatttata ttgttattat acacctttaa atttaaaatg caactgatat
       61 gctcctaaaa cttaaaattt tttaactttt atatgataca gaaatctaaa aaaaatgagc
      121 ttcctactca cttatatagt aggaagctca tttttttctt attttttctc aataggagca
      181 acacttgcta gtaatttctt taaaccaact tctggaaatt tgattttcaa ttccatcgtt
      241 tttccggagc ctgaaacctc aagcacagtc ccgtctcccc attttttatg gtgagcgata
      301 tcgccaatct gccaagtgac ctcttctaca gagctattag aaccaaacgg taaaactgag
      361 ctagttgaag ctgatggtat cgtatgtgcc tgcattggct gtgctgattg tcttacttga
      421 gcctgggcct ttcgagcttg taaggcttct gataggctca tcccttgtcc aaactgtgtg
      481 tgtgtttcag tagaaaaacg cacaccaaat gaagattgtg ctggtcttgc caatccttta
      541 taagagagta gttcctctga aatttctttc aagaagcgtg ttggacggtt ataactactt
      601 ttaccaaaga gggttctggt gttggcattg gtcataaaga gaacttcttc agctcttgtg
      661 attccgacat aagctaaacg tctttcttct tccaattcat ctggatcttc agaggcacgt
      721 gataagggga agacaccttc ttccatacca attaagaaaa caacagggaa ctccaagcct
      781 ttggcagcat gtagggtcat taaggttact tcagcagctt ctgcttggga atcatctgta
      841 tcagcaatca gtgctaaatc gtttaaaaaa cgtcccaagc gatcaacacc ggtttcgtct
      901 tcttcttgag aggcacttga ctcgtcaaaa tttttggtaa cagataagaa ttcttcgata
      961 ttttcgatac gggcttggct ttccaatgta ttttgcaggc gtaagctatc taaataacct
     1021 gttttttcta acaaagcttc tgctaagtcg gtgatactca tctgatctag gtcttgacgt
     1081 agctgaccga gaatattggc caagtccatg atagcttgtg ctgctttacc tttcaagggg
     1141 gacatcaata gatttgaagc tgcttctaat aaagactggt cactctcata ggcaaactga
     1201 cgcagtttat caagcgttcc tggaccaaca cctcgtttag gctcattcac aatccgctca
     1261 aaagaaatat tatcagcagg gttagcaaca atggttaaat aggcaatcaa atcccgaatt
     1321 tctttacggc tgtaaaactt ggtgcctcca accatggtgt aaggaatatt ggattttaag
     1381 agtgcttctt caatggtccg agattgggca ttggtacggt ataaaacagc gaaatctttg
     1441 aagttttttc caagctcttg actcatattg ctaatggttg aggccacaaa tactgcctca
     1501 tctcgctcat catttgcccg gtaataaacc agttgttcac catccgcatt ttgtgtccaa
     1561 agtttcttag gacggcgatt acggttattg ttaatcacgt cgttagctgc ttgcagaatt
     1621 ttcttggtag agcgatagtt ttcttctaaa agcactacct tagcatctgg gtaatctttt
     1681 tcaaaatcaa gaatattttg catgtcagct ccccgccaac catagataga ctgatcagcg
     1741 tctccaacaa cgcaaatatt tttaaagcga gaagctagta atttaattag ctgatattga
     1801 gcatggttgg tatcttggta ctcatccaca tgaatgtatt ggtaacgctg ctggtaataa
     1861 gctaacacgt caggattagc gtcaaacagg cgtagcgtca tcatgattaa atcatcaaag
     1921 tcaagtgctt cgctacgtcg taattcttcc tgataagctt tgtaacacct cgctacgatt
     1981 tgactataca tatcagcagc ctgtgcctcg tatccctttt catcaagcaa atcattttta
     2041 gcgtttgaaa tagttcctaa aatagaacgt tcattccact ttttagggtc tatatttaat
     2101 tgttttaaaa tgcgcttcat caacgttcgt tgctcacctg gatccacgat tgtgaagttt
     2161 cggttgtaac caatgtgatc agcctcacga cgcagaatcc gtacacacat ggagtgaaag
     2221 gtagcaatta aggtatcttt agtagctgga tttaaggcca aggccctttc tttcatttca
     2281 cgcgcagcct tattagtaaa ggtaatagct aaaatattcc aaggattgac aaatttttca
     2341 tcaattaaat aggcaatacg atgggtcagt acccttgttt taccagaacc agcccccgcc
     2401 ataatcaata aggggccttc agttgtttga acagcttgtg cctgccgatc attcattcca
     2461 tttaataaag gattcatgct ttctccttaa tctcgttcag tgacatctct tttatcaacc
     2521 ttaaaattat atcatgtttc caagaaaaat agcaaagaag accccaaaag taaagagatt
     2581 ccttttttct agtttaggat cagatattta aaaataatag cgatttctta aagcattcct
     2641 tatttttttg ctattttggt tgacttcatt cgttttttga ggtatgatag tcctaattta
     2701 ataaaccgaa tgatgtcatg caggagaaga atttttttcg ccgaaggagt tatactctca
     2761 ggtgttcagt ttttgaacgg gactgtttga tggacggact tctggagaga ccttattagg
     2821 cgccgaaggg gcaaggcata ctgctcaatc tctcaggcaa aaggacagaa ggtaaaatac
     2881 aaacaccatt aagaacagtc ttagtctttt ttgtgtttgc tgttttatca ttgcttcaga
     2941 agttgtctca aagaaagaga tagctttttt cttttggcgt cttcgatgac ttttaggaga
     3001 gaaagatgat agcactcgtt aaattaattg ataaccttgt ttggggaccg cccctcttaa
     3061 ttttattggt tgggacgggg atttacctta ccagtcattt aggattaatt caaatcttaa
     3121 aactaccaag agcctttaaa ctcatttttt cagatgacga aggacatgga gatatttcat
     3181 cctttgctgc tcttgcaact gcccttgccg ctactgtcgg aactggtaac attgttgggg
     3241 ttgccactgc tatcaagtct ggtggtcctg gagcgctctt ttggatgtgg gttgccgctt
     3301 tttttggaat ggccactaag tacgctgaag gggtactagc gattaaatac cgtacaaagg
     3361 atgccaacgg tcatatttct ggtggtccta tgtactatat tgttaatggc atggggacaa
     3421 aatggaaacc cttagccatt ctttttgcgg gttcagggat cctagttgcc ctatttggaa
     3481 taggaacctt tgctcaagtg aactcgatca cctcgtcttt aggtcatagc tttggcttat
     3541 ccccacaaat ggtcagtatt gttttagcta tctttgtggc tgccattatt tttggtggca
     3601 ttcattccat ttccaaagtg gctgaaaaag tcgttccttt tatggctatt ttttatattc
     3661 tatctagttt agcagttatt tttagtcact accaacagct acttcctgtt attcgtttag
     3721 tctttcaatc agccttcact ccgacagctg ctattggagg ctttgctgga agtctcatga
     3781 aggatgccat tcaaaaagga attgcacgcg gtgtcttctc caatgagtct ggactaggat
     3841 ctgcacctat tgctgcagca gcagctaaaa ccaatgaacc cgtggagcag ggactgatct
     3901 ccatgacagg aacttttatt gatacgatta ttatctgtac cctaaccggc ctatctattt
     3961 tagtaacagg ccaatggact gggcagctcg aaggggctcc tctgacccaa tctgcctttg
     4021 ccactgtgtt tggaaattta gggacttttg gcctaacctt ttccctagtt ctcttcgcct
     4081 ttacaacgat tttaggatgg agttattatg gagaacgctg ctttgaattc ctctttggca
     4141 ttacacatct cacctacttc cgtattgtct ttatcttaat ggtaggccta ggaggcttcc
     4201 ttaagttaga actaatttgg gttttggctg atattgtcaa tggtttaatg gcacttccta
     4261 acctgattgc cctcctagct ctctcgccag ttgttatttt agaaaccaag cattacttta
     4321 ttaagtaaac atgacgttag tactacccag ttatacctag tcttcttctg ccaagttcaa
     4381 gacgctaggc ttttttctta agcccctttt tatggtataa tataaagttg aaatcaaagg
     4441 agttattatg acacaggatc cgattgcaaa tttaaaacta gccagaaagg gcccaatcgt
     4501 tagtattatt gtctacttgt cgcttagtgt tgccaaatta ttagctggtt atttgttaaa
     4561 tgcaagttcc cttattgctg atggatttaa caatttatcg gatattgtgg gaaatgtagc
     4621 cctgcttatt ggtcttcact tagctagcca accagccgat gccaatcata aatttggtca
     4681 ttggaaaatt gaagacttat ccagccttgt cacttctttt attatgtttc ttgtaggttt
     4741 ccaagtactg attcacacaa ttaaaagtat ctttagtggt cagcaagttg atattgaccc
     4801 tcttggggct attgtcggta tcgtttcagc ttttgttatg ttaggggttt atgtctttaa
     4861 caaacgtctt tccaaacgtg taaaatccag tgccttagtc gctgcttcta aggataatct
     4921 agctgatgct gttacttcta tcggaacatc aattgctatt atagcagctt ctttgcattt
     4981 accagttatc gatcatatag ctgctatgat cattacgttc tttattctta aaacagcttt
     5041 tgatatcttt atggaaagtt cgtttagttt atctgatgga tttgatagcc gtcatttgaa
     5101 aaaatacgaa aaagccattt tagaaatccc taaaattgtc gccgttaagt ctcaacgagc
     5161 taggacctat ggtagcaatg tctatcttga tattgtactt gaaatgaatc ctgatctttc
     5221 agtctatgaa agtcactcta ttacagagaa agtggagcag ttattgagtg accaattttc
     5281 tatttatgac attgacattc acgttgagcc tgccatgatt cccgaagaag agatttttga
     5341 taatgtcgcc aaaaagctct accgctacga aaaattaatt ttgagtaagg ttcctgacta
     5401 tgaccactac attgctaagt ctttccaact gattgatgcg aatggccaaa cagttaacta
     5461 tgaacaattt ttgaaccaag aaatttatta tccaagtaac ttcaaccatt ttcagattga
     5521 atccattagt caaaaaacga tgttggtaac ttaccaatta aatggcaatc aacgtaccag
     5581 tatttggagg cgtcatgaat cttggtcctt actcttccac caaattaccc ctatcgctaa
     5641 gaaacaatta catcacacac actatcgtat tgtaaaaatg taaaaacatc acttctctta
     5701 taacataact atacttcatg atattcctaa agcgattcct agtcccaaaa tgataagtga
     5761 aatagttaaa aaatccctac aatttgtttt taaacagatc atagggattt ttttaagaat
     5821 acacgttttc atattgaatc ttattagttt agggggttaa acaagattca atagtgacgg
     5881 ttgaacaata ccttaaattg gtacatcatg ttaaaggcaa aaagggctac aggtgactca
     5941 ttgtttatga gaacatcacc tcaaactcta caatggtaag atatttaaaa tctttaccta
     6001 ttctatatcc taatgtaatc atctacctat acaacacatt acttatacac tctatgactt
     6061 aagagctgtt tccaaagcat cttgcacagc aataacttca tcgtcaactt gttgaacagt
     6121 ggttgtcgga tttagttgga caccaaccgc atgtgtgata gctttgttaa gtctattgta
     6181 aacgtcaaat ggtttgattc ccaaaacctt tttatctctt tctaaacgag tgttccaaat
     6241 agctttattt agtttagctt tagtatagat agtagcacgg tctgttggct gtaaatcagg
     6301 ataattgata actttttcct caagtgcttt aatttcttgt acttgagctt tgatagcgtc
     6361 aacagatgca aatggatcta taatacgaat gactaattta gtaatagcaa accccatatc
     6421 agtatgcgct ttttctactt tatgagttaa ttgggttgtg gaaaatacga ttgctttgat
     6481 agcatctgat aatgcttcta ctcttgcccc aattgaacta aaatcataga tcgtttcagt
     6541 attgaagcgt atagaactct tcatgtgatc aacagcatcg atagctttgt taacagtagt
     6601 ctcaatatca gtacctttag cttcatgttt aatagcttct aattgttgat gtccctcatc
     6661 aagcttttgc actagagcat ctctttgaaa atttgcttgg ttgttattca ttaaaatagt
     6721 atcgggattt gaagcatcat cagctaaaac tgagtgcgtc atagttgaaa ataaagctaa
     6781 tccagcaaca actgttgaaa gacagagaag gtgtttgggt ttcatattat tcctcctgaa
     6841 tataataaat ctatttaaat agttaagtga agttaaatta atttataagc gcttataacg
     6901 ttatcatact acttgttttt actaaggtca atatttcttt aatttccaga aaataagaga
     6961 atttcgcaaa aataatcatt ttttaatgtc
//
LOCUS       DAUGQX010000064         6725 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUGQX010000064 DAUGQX010000000
VERSION     DAUGQX010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6725
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.064"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..2541)
                     /locus_tag="VIA51_001618"
     CDS             complement(<1..2541)
                     /locus_tag="VIA51_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ8683553.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVILGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLRLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPIKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPPNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEMRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLL"
     gene            complement(2624..4243)
                     /locus_tag="VIA51_001619"
     CDS             complement(2624..4243)
                     /locus_tag="VIA51_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8683554.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(4322..5194)
                     /locus_tag="VIA51_001620"
     CDS             complement(4322..5194)
                     /locus_tag="VIA51_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8683555.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    5317..5558
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5613..6635
                     /gene="trpS"
                     /locus_tag="VIA51_001621"
     CDS             5613..6635
                     /gene="trpS"
                     /locus_tag="VIA51_001621"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEQ8683556.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQIGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
BASE COUNT         2339 a         1082 c         1224 g         2080 t
ORIGIN      
        1 caaaagcata taagcgataa ttcctacaca agatagagat aaccctaatt taaaaccatt
       61 aggaataaag gtaaggataa cacgtccctt tcctttagga atagtaactg atagaaatcc
      121 tccttgtgct tttttgactg gaagattttt cccatctttt tgtgctgacc aacctttatc
      181 gtaaggaagt gtaaaaataa gagaaccttt cgtttttgaa ttataatcag tgattaccgt
      241 attactttta gcgtaagtat gaacattttt ttgtttaatg ctattcattg cttcaaggta
      301 agattcaata gacaaactat aaaaatgagg ttccttaaaa ctaatttgtt tattttttgg
      361 aaaaacaaac gaaaatgtag caactttggc atcggcgaaa tatcctaaat caaaaaaaga
      421 gtaagcgtta tctgtagtat atatgaaatt atgattatct gtctgaatac gcatctcttt
      481 agcatcagga tttgaaaata taatattggg tatgctaaca tagagttgac tatgtttagg
      541 gatgttaatt tgataattaa gggtaacgga gttttgataa tcagaagctt gtgcagatat
      601 ttgtccgtta aattgattag caccagaaat aagttgagct ggctgtaagt taaaataggt
      661 taaagatttc ccacttagtt ggttaagtaa tttggtttgg ttatcaaggg tattgacatt
      721 taggttgaca tctttgtaaa cattacgtgt taatatagct aaagggctac tatagtgatt
      781 ttgataaaga gtagtattcc cgctagtttt tagttttgta aatccaaatt tatttggagg
      841 tccttcgcta agattatatt ttataccaag tagactgtcc ataataatag tattgttttg
      901 gtatctaagg tttaaatttg tgcctttaga ctgaaatccc aatcgatcca ataaagaact
      961 agatagtcta tttcttacag aggaaaattg tgaaatgccg taataattaa atttcatgct
     1021 atcgttccct gtttggggaa gtagcctttc cattctaaaa aaaggttgac tattttttga
     1081 cacagagttg acaaggttgt taatatcctt taattgacta ttatatatct gtcgtgatgg
     1141 gaatccccac tccttattaa ttccttgaag ctggtagtag gtgtttaacc ctgattcaag
     1201 aaggctaaag ataagtatga aagcagaaat aaaagtagat gggatttgag aatttctaaa
     1261 cgaaaatagt gaaatagtat aacctaataa taaaaaaaca ctaagtaaaa aaagagttaa
     1321 aggtagaaaa ttatattgtt gagaaaagct ataaggaaga gatgtcagta taatgaggaa
     1381 aataaaagca aaacctgctt ttatttgagt cacttctttt agtcgagaga gagtctcaca
     1441 tgcgagtaat aggataacta tggaaaaaga ccaagcgtag cgatgcaaaa acatatttgg
     1501 tgagtgcatc ccctgccaaa aaagatcaag tggctgtagg taaaaactta ttataataaa
     1561 agttaacaag caggcattgg ctaattttat ttttaaaggg atactttcta aagtaaaata
     1621 aataacacta agcattaggg gaaataatcc tacgtaaatc ataggcagag cattaaactt
     1681 ggtagtatcg tacactccta ttgagagctt agcaggtata tccaaaaacc aagcattgtt
     1741 cgtaactaac tgttttatcg gggatagatt ctctccataa gttgacaaat ctagataggt
     1801 aggaagtatt actagagcac ttgttaaagc agcacatatt gacacagctg taaacctaac
     1861 aaaagcgata aacattttgt taaaatcatt gagacgtaaa agacaaacta aggcgtaaag
     1921 aatacaaaaa agagcaatca tgtagccaaa gtagtaattt tgaatgaata ataatgatat
     1981 cgaaagataa taagttctgg ttttattttc tgtgataagt ttatttaatc caagtataac
     2041 aagtggaaga agaatgaaaa catctaacca agaatttagt tccatttgac ttgtcaagaa
     2101 gctcattaag ctataaaaaa ctgagatgga aatcatcaag aaagcactga tttttggata
     2161 taatctatga aaagaatagc atgcagctaa tcctattaac ccaaatttta tcaaggtaaa
     2221 caaatagata gcatctggca tagaggttaa attaaaaaag aaaagtaatg gagaaaagaa
     2281 actgccaaga taataacaca ttaaagcata aaaatttatc cctagtccgc ttgtaaaggt
     2341 ataaaaaaaa ctatcagaac cgtgcatgat gttacgaaag ttctgcgcaa aaataacata
     2401 ctgatgaaaa gcatcactag ctagaattgt tttatcacta ttataataaa tgcccatcga
     2461 tagaaggatg ataaatataa tactaagagg gaacaaaaaa ctagcaagtc cagcaattat
     2521 ccatttatta ttatttttca taaattatat ggtctttcgt ttacaaattt taaaaaagag
     2581 gctaggaaga gatcttctta gccacctcat ttatcataag gttttatttc caaagttcag
     2641 caactcgggc ttggacttct ggattgtcaa ggaattcgtc ataagtttca tctatacggt
     2701 cgataacacc attttttgaa ataacaacga tgtggttagc aatcgtttga ataaattcat
     2761 ggtcatgact ggcaaagata acagattctt tgaagtcttt gattccatca ttaagacttg
     2821 aaatagattc caaatctaag tgattagttg ggtcatcaag aataagaacg tttgatttca
     2881 atagcatcaa cttagaaagc atgacacgca ctttttcgcc accggaaaga acgttaacag
     2941 attttttaac ttcgtctcca gagaaaagca tccgtcctaa gaacccacgt aaaaaggtat
     3001 catcatcttc accttttgag gcaaattgac gtaaccattc aagaatagat tcttccgtgg
     3061 caaaatcttt tgaattgtct ttaggcaagt aagaacgact tgttgtcact ccccatttaa
     3121 tggttccttc gtagtcaata tcatctgcta aagcacgcat aagagcagtt gtctgaatat
     3181 cattttgacc aataatagca gctttgtcac ctggacgtaa aatgaaactg atattatcaa
     3241 tgattttctc tccatcgatc gttacagaaa gattttcaac agtgaggaag tcatttccca
     3301 tttcacgctc tgctttaaaa ttaataaatg ggtatttacg gcttgaggga acaatttctt
     3361 ctaattcaat cttatcaagc atttttttac gagaggttgc ttgttttgat ttagatgcgt
     3421 ttgctgagaa acgggcaacg aattcttgta attctttgat tttctcttct gctttagcat
     3481 tgcggtcagc ttgtaaacga gcggccagct cagaagattg tttccagaaa tcgtagttac
     3541 ccacaaagag tttgatttta ccaaagtcaa ggtcggccat gtgagtacat actttattca
     3601 agaagtgacg gtcatgggaa acaacgatga ctgtattttc aaaatcaatc aagaaatctt
     3661 ccaaccatga aatagattga atatcaagac cattggttgg ctcgtcaagt aataaaacgt
     3721 caggcttacc aaagagcgct ttagcaagaa ggactttcac tttatctcca ttagccagtt
     3781 cactcatatt ttggtagtga aggtcttctg gaatatttag attttggaga agttgagaag
     3841 cttcactttc tgcctcccag ccacctaatt cagcaaagat accttctagc tcagcggcac
     3901 gaaccccatc ttcttctgaa aaatctgctt tcatatagat agcgtctttt tctttcatga
     3961 tattgtagag ttgttcatta cccatgatta caacatcaat cgcacgttct tcttcataat
     4021 caaaatgatt ttggcgaaga acagataagc gttcgtcagg tcctaaagag atatgaccag
     4081 tacttggttc aatatctcct gcaaggattt taagaaaagt tgattttccg gcaccattgg
     4141 caccgattaa gccgtaagta ttgccggctg tgaatttgat attaacatca tcaaatagtt
     4201 ttcgatcact aaagcgtagt gatacatcag aaactgtaag caatttgtca cctcatttta
     4261 tttatctaag cttcattgta cctaaaatag tccccttttt caatcagaaa agggctaatc
     4321 actacatagg caataaaacg tctttgtctt cacgtttgta ttgtttagtc aaactaaatc
     4381 ctcttcccat aacttgagct gctggcatga caacaataaa ggctgtatcg tcaatttcga
     4441 ggattttttc ttggagagta ggtaattcgt gacttgatac aatagccatt aacataattt
     4501 tatcagaagt agtataacca ccgcgaatag gaagtttagt cactccacga tccataacag
     4561 ttgtgatata ttctcgaata gcttgataat ctttggaaat aatcataaca tttttggatg
     4621 agtcaaagcc attttccata acgctaatca cataaccaat tacgaaaagt ccaatcgtag
     4681 aatacatcac gtcatctgca gaaagtgcaa taaatcccat aaggacacta ataccatcta
     4741 caattgtcat tgcaactcca agagataaag gagagtattt atgaagtatt tgtgttagaa
     4801 ttccagttcc tcctgtcgaa gagtttcccc aaaaaaccat tcctaaacca atgccacaga
     4861 taataccacc aaaaatagct gctaacaact gattgtgtgt cagagtaggt aatgaattgg
     4921 ttgaacggat ggcaatagga tatatccaag aaccataaag tgttttaata aaattttgtt
     4981 ttccaagaaa gaagtaacac attaataata agggaatatt actagccatt aaaaaaagcg
     5041 acggactaat gccaaataga gcttttataa caactgcaat accaaccata ccccctgatg
     5101 caatatgatt gtcgacaaac attgtattga aaccaatagc tgttatgaat gagccaattg
     5161 tgacaagtag taaatcaatc cctcgttttt tcatgctttt aatctccttt ataactggtt
     5221 aaaaatagta gactcattat ctcttaaatg tactgagacc gtcaagtcat attttcaaaa
     5281 aatctggtga acttgacaag aagtttaaaa tttcatagaa taaatctaaa ttagaagagt
     5341 attcttttca tgtttttaga gagttagtgg ttggtgcaag ctaacaacag aaaaggtgaa
     5401 atggactaat gattatttga aaggaaacca taactttcag gttggcaccc cttaccgtgc
     5461 agcttctttc attgagaaga ttgagatagt atctcgtttt gataaagcag atgctaattg
     5521 aggtggtacc gcgtattact tgtaataacg ccctcacgtt ttaatagcgt ggggactttt
     5581 tgctatatca agagatagtt agggagaaaa tgatgacaaa acctattatt ttaactggag
     5641 atagaccaac tggaaaatta catttaggtc attatgtcgg aagtcttaaa aatcgtgtct
     5701 ttttacaaaa tgaaaacaag tataagatgt ttgttttctt ggccgatcaa caggcactga
     5761 cggatcatgc taaagaatcc gaattaattc aagaatctat tggaaatgtt gccttggatt
     5821 acctctctgt cggtttggat ccgaagcaat caacgatttt tattcaaagt cagattccag
     5881 agctagctga attgagcatg tattatatga atctggtatc attagcacgt ttggaaagaa
     5941 atcccactgt taaaaccgaa attgctcaga aaggttttgg cgaaagtatt ccatctggtt
     6001 ttttggttta tccagtatca caggccgctg atattacagc atttaaagcg aatttagtac
     6061 ctgtaggtaa cgaccagaaa ccgatgattg aacaaacacg tgaaattgtg agaagtttta
     6121 atcatactta ccatacagac tgtttagtag aacctgaagg tatttatcca gaaaatgaaa
     6181 aagctggacg cttacctggt cttgatggca atgccaaaat gtctaagtca ttgggaaatg
     6241 gaatctatct ctcagatgat gcagataccg ttcgcaaaaa agtgatgagc atgtatactg
     6301 atccaaatca tattaaaata gaagatcctg gtcaaattga agggaatatg gtctttcatt
     6361 atttggatat ttttgctaga aaagaagatc aagctgatat cgaagcaatg aaagagcatt
     6421 atcaaatagg tggtttagga gatgtgaaaa cgaaacgcta ccttttagat attttagaac
     6481 gtgaattagc acctattcgt gaaagacgtt tggagtacgc taaagatatg ggagaggtgt
     6541 tccgtatgtt acaagaaggt agtcaaaaag caagaactgt ggcagccaag actttatcag
     6601 aagtgaagtc agcaatgggt attaattatt tttaatgttt tagagaaaaa gctaagttag
     6661 taatgataag ataattacta ttatcaaaac aggacctaat ttgtcatttc tttacaggat
     6721 agtag
//
LOCUS       DAUGQX010000065         6226 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUGQX010000065 DAUGQX010000000
VERSION     DAUGQX010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6226
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.065"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(38..109)
                     /locus_tag="VIA51_001622"
     tRNA            complement(38..109)
                     /locus_tag="VIA51_001622"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74..76),aa:Glu,seq:ttc)
     gene            complement(304..1068)
                     /locus_tag="VIA51_001623"
                     /pseudo
     CDS             complement(304..1068)
                     /locus_tag="VIA51_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1233..1306
                     /locus_tag="VIA51_001624"
     tRNA            1233..1306
                     /locus_tag="VIA51_001624"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1267..1269,aa:Arg,seq:tct)
     gene            complement(1463..1942)
                     /gene="rlmH"
                     /locus_tag="VIA51_001625"
     CDS             complement(1463..1942)
                     /gene="rlmH"
                     /locus_tag="VIA51_001625"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEQ8683557.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            2154..3377
                     /locus_tag="VIA51_001626"
     CDS             2154..3377
                     /locus_tag="VIA51_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEQ8683558.1"
                     /translation="MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            3436..4242
                     /locus_tag="VIA51_001627"
     CDS             3436..4242
                     /locus_tag="VIA51_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEQ8683559.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            4475..5830
                     /gene="dnaA"
                     /locus_tag="VIA51_001628"
     CDS             4475..5830
                     /gene="dnaA"
                     /locus_tag="VIA51_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEQ8683560.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            5985..>6226
                     /locus_tag="VIA51_001629"
     CDS             5985..>6226
                     /locus_tag="VIA51_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002981935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ8683561.1"
                     /translation="MIQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEAS"
BASE COUNT         2093 a         1083 c         1051 g         1999 t
ORIGIN      
        1 cggaaaaaga aaaaaattgc caaaatgaca attgcgatag tccgtacggg attcgaaccc
       61 gtgttaccgc cgtgaaaagg cggtgtctta accccttgac caacggacca gaagttttgg
      121 aggatatctc cttaacactc ttactattat agcagattga ttttttttgt ctatactttt
      181 ttaaaaaaaa tttgattttt tttaaaccgc aagttgtcaa gtcaagtgca acgagttcat
      241 agataactag agttccagag gttaagctgt tcgggatagc tcaaacagga attttgagga
      301 ttgctattga agaagtcgtc ttaggcgctc attgatggca gtaatatcat tgtcaagttc
      361 ttcagaggtt agtggattaa gtgagattcc tttagggaca tattctctga ggagaccatt
      421 gaagttctcg tttgttcctc tctcatgtga agaataggga tgtgcaaagt aaacgtcaac
      481 agcttttaag tctgagagta aactaaactc agaaccatta tccgctgtga tggatgcaat
      541 aggatactga ctgatgagat gcgtgacagc acggttaatg gtttgggact gcttgtcttc
      601 tatagtgcat agcgtgtctg gcgctctacc aaagtcaaca taacagcttc acttttggtt
      661 ttcttgccga gagccaaatc aatctcccaa tgcccaaatt cagaacgatc attaatatat
      721 tctggacgtt cttcgataga tttacctaaa gtcttcttat tcgtcttcat gactttctta
      781 gaacgttttc tgatactaac catcttagac aaatctattg gtttcataga cacgttgtct
      841 actatcagcg aaataggcgt tgaagaaggt ttgttttcca ttcttatcct ttacctgatc
      901 tactgaacca cgttttattt ctcggcagat tgtagaacgg tgactaccca gaagtcgagc
      961 aatctcaacg ggtttctttc ccattttaag ataagcagca atttcacccc gttctgtggc
     1021 tgaaagatga gaataggatg attttctggt agaattaata ttagacatgt tcatctgctt
     1081 tccatactga attggggaat tctagtatat cagacgaaca tgtctttttt gttgtacttc
     1141 attttataac gcgggatata atgttatttt ctagtttttt caaaataaat attgacagtt
     1201 ttagataatt tttgttaaaa tgatgtggtt aaggtctcat agctcagctg gatagagcat
     1261 tcgccttcta agcgaacggt cgcaggttcg aatcctgctg ggatcaaaga taaaaaagca
     1321 ctgttttagt gctttttttg tatttacctt agtgtattga aaagatagga tttagtacgt
     1381 ctttttttaa tatttgcttt taattatacc gaactattat ctaataaagt ggtaagagtt
     1441 agttattcca gttcacactc tcttacttat gataaggact gccttgtgta atcataaaag
     1501 cacgataaat ttgctcagta aggactagac gcattaactg atgaggtaag gttaacaatc
     1561 caaaactcat tagcatatta gctctttttt taataattga atctaatcca agactcccac
     1621 caataataaa cgtgatagtt gaatatccct taacagtaac ccctgatatt aattcactaa
     1681 atgtctctga aggaaactgt tttccttcaa tagctaatgc aattacaaaa tcacgttccc
     1741 caattttttt atggattcgc tgagcttctt tactcataat caattgatta tcagcaaaac
     1801 ttgctttatc tggtgttctt tcatcagtta actcaatcat ttcgaattga caaaaacggg
     1861 aaagtctttt ttgatattct gaaataccat ctttgaggta tctttctttt agttttccaa
     1921 cacaaattag tttcactttc atagcttaat tgtatcacaa gaacattact ttttacacaa
     1981 tttatccaca agttattttt cttcaactac taataaaaac ctttgtacaa aggtctttat
     2041 tagtaaaaag aaaagtaatc cacaggctgt ggattacttt tctttttttt atttttaagg
     2101 tataattaag caaagttcta taagctatgg acaaataatt cggaggacaa aacatgccaa
     2161 gtatgaaaca tatcttaaaa tccttaagta ttttactaat tggattttta ggaggattaa
     2221 tagcaattat tacattcaat aatctctacc cacattctcc atcaaaaata aattcaggta
     2281 aggcaacaac tagtaatatg gtttttaaca acacaaccaa tactactaaa gctgtcaaag
     2341 ctgttcaaaa tgcagttgta tcagttatta attatcaaga taacccttct tcatcccttt
     2401 ctaaccctta tacaaaactc tttggagaag ggcgttcaaa agagaataag gatgctgaat
     2461 tatctatttt tagtgaagga tctggggtca tttatcgaaa agatggcaac tccgcttacg
     2521 ttgttactaa taaccatgtt atcgacggag ctaaacgaat tgaaattctt atggcagacg
     2581 gatctaaagt tgttggtgaa ttagttggag ctgatactta ttcggattta gctgttgtta
     2641 agatctcttc agataagata aaaacagtag ctgaatttgc agattctaca aaactaaatg
     2701 ttggagaagt tgctattgct atcggcagcc cactaggaac acaatacgct aattctgtta
     2761 ctcaaggaat cgtctctagt ttaagtcgta ctgtaacttt aaaaaacgag aatggtgaga
     2821 ctgtctcaac aaatgctatt cagacagatg ctgctattaa ccctggaaac tctggtggac
     2881 cactaattaa tattgagggg caagtaatcg gaattaattc aagtaaaatt tcttctaccc
     2941 caactggtag caacggtaat agtggtgctg ttgaaggaat tggttttgct atcccatcta
     3001 ctgatgttat taaaattatt aaacaactag aaactaatgg tgaagttatc agacctgctc
     3061 ttggaatatc catggtcaat ttaaatgact tatccacaaa tgctcttagt caaattaata
     3121 ttccaactag tgtaactggt ggtattgtag tagcagaagt taaggaagga atgccggcat
     3181 ctggcaaact tgctcagtac gatgtgatta cagaaattga tggcaaaaca gttaattcaa
     3241 ttagtgattt acaaagtagt ctatacggac acgatattaa tgatactatt aaagtaactt
     3301 tttatagagg aactacaaag aaaaaagcag atatcaaatt aacaaaaact actcaagatt
     3361 tgactaaaac gcagtaaaca agctacctaa atactattac attttatcac ataaaacagt
     3421 ccaaaggact gttttatgtt tcttattcta tccaggaact cccttatgac aaaagaatta
     3481 ttgatagacc taccaattga agatattgtt acaaatccct atcagccaag gatacaattt
     3541 aatcaaagag aactccaaga cctagcaact tctattaaat caaacggcct cattcaacct
     3601 attattgttc gaaaatctga catttttggc tatgagttag ttgctggaga acgacgactt
     3661 aaagcttcaa aaatggctgg tctaaaaaaa gttccagcta tcatcaagaa gatctccaca
     3721 ctcgagagca tgcaacaagc tatagttgaa aatttacaac gttctaacct taacgctatc
     3781 gaagaagcta aagcctatca gttattggtt gaaaaaaaac acatgactca cgatgagatt
     3841 gctaaatata tgggaaaatc aagaccttat attagcaata ccttacgtct gttacaactc
     3901 ccagcaccta tcattaaagc aattgaagaa ggaaaaatta gtgcgggaca cgcgcgtgct
     3961 cttttaactt tgagtgatga taagcaacaa ctgtacctca ctcataaaat acaaaatgaa
     4021 ggcctaagtg ttaggcaaat tgagcaactg gttacttcta ctccaagttc gaagctatct
     4081 aaaaaaacta aaaatatttt tgccacttct ttagagaaac aattggctaa atcattggga
     4141 ctctctgtca atatgaagct gacagcaaac catagtgggt accttcagat atctttttcc
     4201 aatgatgatg aattaaacag aattatcaac aagctaaagt agcttgttga tattctgttt
     4261 tttctttttt agttttccac atgaaaaata gttgaaaaca atagcggtgt ccccttaaaa
     4321 tggcttttcc acaggttgtg gagaacctaa attaacagtg ttaatttatt ttccacaggt
     4381 tgtggaaaaa ctaactatta tccatcgttc tgtggaaaac tagaatagtt tatggtagaa
     4441 tagttctaga attatccaca agaaggaacc tagtatgact gaaaatgaac aaattttttg
     4501 gaacagggtc ttggaattag ctcagagtca attaaaacag gcaacttatg aattttttgt
     4561 tcatgatgcc cgtctattaa aggtcgataa gcatattgca actatttact tagatcaaat
     4621 gaaagagctc ttttgggaaa aaaatcttaa agatgttatt cttactgctg gttttgaagt
     4681 ttataacgct caaatttctg ttgactatgt tttcgaagaa gacctaatga ttgagcaaaa
     4741 tcagaccaaa atcaaccaaa aacctaagca gcaagcctta aattctttgc ctactgttac
     4801 ttcagattta aactcgaaat atagttttga aaactttatt caaggagatg aaaatcgttg
     4861 ggctgttgct gcttcaatag cagtagctaa tactcctgga actacctata atcctttgtt
     4921 tatttggggt ggccctgggc ttggaaaaac ccatttatta aatgctattg gtaattctgt
     4981 actattagaa aatccaaatg ctcgaattaa atatatcaca gctgaaaact ttattaatga
     5041 gtttgttatc catattcgcc ttgataccat ggatgaattg aaagaaaaat ttcgtaattt
     5101 agatttactc cttattgatg atatccaatc tttagctaaa aaaacgctct ctggaacaca
     5161 agaagagttc tttaatactt ttaatgcact tcataataat aacaaacaaa ttgtcctaac
     5221 aagcgaccgt acaccagatc atctcaatga tttagaagat cgattagtta ctcgttttaa
     5281 atggggatta acagtcaata tcacacctcc tgattttgaa acacgagtgg ctattttgac
     5341 aaataaaatt caagaatata actttatttt tcctcaagat accattgagt atttggctgg
     5401 tcaatttgat tctaatgtca gagatttaga aggtgcctta aaagatatta gtctggttgc
     5461 taatttcaaa caaattgaca cgattactgt tgacattgct gccgaagcta ttcgcgccag
     5521 aaagcaagat ggacctaaaa tgacagttat tcccatcgaa gaaattcaag cgcaagttgg
     5581 aaaattttac ggtgttaccg tcaaagaaat taaagctact aaacgaacac aaaatattgt
     5641 tttagcaaga caagtagcta tgtttttagc acgtgaaatg acagataaca gtcttcctaa
     5701 aattggaaaa gaatttggtg gcagagacca ttcaacagta ctccatgcct ataataaaat
     5761 caaaaacatg atcagccagg acgaaagcct taggatcgaa attgaaacca taaaaaacaa
     5821 aattaaataa catgtggaaa agaatatctt ttatgaaata gttatccaca agttgtgaac
     5881 atccatttag tcttggattc tctcgtttat ttagagttat ccactatata cacaagacct
     5941 actactacta cttattatta tacttattaa ataaaggagt tctcatgatt caattttcaa
     6001 ttaatcgcac attatttatt catgctttaa atacaactaa acgtgctatt agcactaaaa
     6061 atgccattcc tattctttca tcaataaaaa ttgaagtcac ttctacagga gtaactttaa
     6121 cagggtctaa cggtcaaata tcaattgaaa acactattcc tgtaagtaat gaaaatgctg
     6181 gtttgctaat tacctctcca ggagctattt tattagaagc tagttt
//
LOCUS       DAUGQX010000066         6220 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUGQX010000066 DAUGQX010000000
VERSION     DAUGQX010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6220
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.066"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..198
                     /locus_tag="VIA51_001630"
     CDS             <1..198
                     /locus_tag="VIA51_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEQ8683562.1"
                     /translation="PDNGMMESFFGILKSEMFYGLETTYQSLDKLEEAITDYIFYYNN
                     KRIKAKLKGFSPVQYRTKSFQ"
     gene            complement(498..1370)
                     /locus_tag="VIA51_001631"
     CDS             complement(498..1370)
                     /locus_tag="VIA51_001631"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEQ8683563.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1594..2904
                     /locus_tag="VIA51_001632"
     CDS             1594..2904
                     /locus_tag="VIA51_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEQ8683564.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KALLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPDALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHSLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPILS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            2982..4132
                     /locus_tag="VIA51_001633"
                     /pseudo
     CDS             2982..4132
                     /locus_tag="VIA51_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4259..4414
                     /locus_tag="VIA51_001634"
                     /pseudo
     CDS             4259..4414
                     /locus_tag="VIA51_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039767.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4461..4991)
                     /locus_tag="VIA51_001635"
     CDS             complement(4461..4991)
                     /locus_tag="VIA51_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEQ8683565.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(4984..>6220)
                     /locus_tag="VIA51_001636"
     CDS             complement(4984..>6220)
                     /locus_tag="VIA51_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HEQ8683566.1"
                     /translation="GKDSGLLLNILLDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQE
                     TFTSLEGRKKVSLYWVCLPMATRTALSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLE
                     NNSITTYRYKMNQEDLAKQFGRWYKQIHGNQKTVCILGNRASESLHRYSGFINKKYGY
                     QKECWITKQFKDVWTASPLYDWSVEDIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVA
                     SPFQDYAVDSLNLYRIIDQETWVKLLGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWK
                     SYTQFLLSTLPVRLRNNYVRKFNKSIDFWHKTGGGLAEETINELIEKGYRIARNGISN
                     YTSFKHSRVIFLDQIPDDTDDIVTTKDIPSWKRMCFCILKNDHICRTMGFGLTREQQK
                     IVAFLKEKYKTSLKELESE"
BASE COUNT         1923 a         1337 c         1006 g         1954 t
ORIGIN      
        1 ccggataacg gcatgatgga atccttcttt ggcattctca aatctgaaat gttttatgga
       61 ctcgagacaa cttatcaatc acttgacaag cttgaagaag ctattacaga ttacattttt
      121 tactacaaca acaaacgaat taaagcaaaa ctaaaaggat ttagtcctgt ccaatacaga
      181 actaaatcct ttcaataatt atttgtccaa ctttttgggg tcagtacact cctagttaac
      241 gactttgatt gattttatta tgatgaatcg tgatttctga aaacaaaatt ttcttcatgg
      301 atttggcgtg gaacttttac aataaaaaca ctaacctctc cctatcgttt tttcaggtga
      361 atgcttggaa ttggtataat aagcggacac gaatcaggtg aaaacaggga aagtatttga
      421 aaaggcgttt aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag
      481 ttagtttatt ttgcaactta gacatcaagg taggttaaac ccttcatgga aaaatcgaga
      541 ctcttagcac tatgggttaa actaccactg gagacgtaat caatcgctaa accacgaaaa
      601 cggctaatag tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt
      661 agagtaatgg cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcaaca
      721 cccgccgccg cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc
      781 acaaaagggg cataggcacg cgcttgagca atcgcctttt gaacactacc tactgccgca
      841 atgtgattgt cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg
      901 ccaactctca cggcatattt ctcaaaaaga cgtaaattag gagtggtttt tcgagtatca
      961 aataccttaa tgcgatcatc gcctaaggct tctacataag cagctgtcat cgaagcaatc
     1021 cctgataaat gttgtaaaaa attcaaggca acgcgttcac atgttaagag gcttctcacc
     1081 gagcctatga tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga
     1141 tgaggattct ggaaggtcac ctcggcatca aatagggtaa aaaccctttg aaaaacggtt
     1201 agccccgcta aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga
     1261 tcaaaaatgg cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc
     1321 aatgtatcat ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc
     1381 tctattttta atatcacttg taagcactag aggcaattgc tattaacttc cgtaggaaat
     1441 cacaaacctg aatacctcat tttaaatccc aacaagtgtc aagacaattg taattttttt
     1501 gtgtataata gtcaagtacc aataggaaac aggtggtctt ttgagcgcca aaattgccaa
     1561 cctattttca tattctaact aaaggacaat tcaatgattc atttaataat aattagcgcc
     1621 attgctctag ccattggaat tggttaccgc accaaaatca atattggcct gctggctatt
     1681 gctttttctt acctcatcgc aaccactctc atgggattaa gccccaaagc acttcttcat
     1741 ttttggccaa cctcactctt ttttaccatt tttagcgtct ctctctttta taacgttgca
     1801 acaactaacg gcactcttga tgttttggct caacacattc tctaccgcac acgcacccac
     1861 cctgacgccc tctacatgat tttatacctg atagcaaccc ttttgtctgc tttaggtgct
     1921 ggatttttca ctactatggc cgtttgctgt cctctagcga ttaccctctg tcaaaaagcg
     1981 gacaaacact ctttgattgg agctcaagcc gtcaattggg gagcttcagg aggggctaat
     2041 ttgataacca gtggctcagg cattgtcttt caaggcctgt ttaagcaaat gggatgggaa
     2101 gagcaagctt tttcacttgg caatcatatc tttatcgtca gcattatcta cccactcatc
     2161 gtcttgcttt tattatcttg ttacatccgc tacagtaagg gaagaacaaa ctcatccttg
     2221 actattgacc aaccaccaat cctcagcaag gtccaaagac aaaccacctt gctcatgatc
     2281 agcagcatgg ttttggtttg gctttttccc ttgttgcatc tcattttccc aaacatcgca
     2341 tggatagcta cttatcgaca aacatttgat attggctttg tctcaatact catggtctgc
     2401 ctcgccttaa ggctcaaatt agggaagcaa gaagccattt tggctaaggt tccctgggct
     2461 ataattatca tgctctgcgg catgagctta ctaatgtctc tagcggtcaa gtcaggttta
     2521 gttacactga tagggcacct cataacaaca accattcctc atttctggtt acctctgttc
     2581 ttttgtgtga tagccggagt gatgtcactc tttagttcca ccctatccgt tgtagcccca
     2641 actctctttc ccatcattgc taccatcagt gctcaaagtc ctcacattga tattcgctta
     2701 ctcacaacag ccactattat tggcgctcta tctactaata tctctccttt ttcatcagct
     2761 ggttccctca ttcaactctc ccttccccat atagaggaac gcagtcttgc tttcaaaaaa
     2821 caaattcttc tgggtgtgcc catcagctta agtttggcac tcttgaccat ctggattctc
     2881 atgctgctag cttccttaag ttagatttat tgtctaactt aaggttggac ttggtataat
     2941 aaagtagaca caaaattaag tggaaacgag gaaaagtcat tatgccaaga aaaacctttg
     3001 ataaagcctt caaactctct gctgtaaaac tcatccttga ggaagagtag cctgtaaaaa
     3061 tggctagttc aactttaaaa attcatccca atagtcttta tcgatggatt caagaatatg
     3121 aaaaatatgg agaaagtgcg ttcccaggac atgggagcgc acttcgtcat gctcaatttg
     3181 agacaaaaaa acttgaaaaa gagcacaaac tgctacagga ggaattagct cttctaaaaa
     3241 agttccaggt ctttttgaag ccaaaccgga aataaaattt cagtttctga aggaaaatag
     3301 tgttagcttg aatagtcatc acgcttgtca aactcttcaa gtctcccgtt caggtttcta
     3361 tgcttattta aaacgtcgtc cctcttcaag gcatgttgag aatgaagctt tgaaggaaat
     3421 gattaaagcc attttctatg aacataaaga gcgttacgga agtgtacgaa ttacccaaga
     3481 actttgtaga cgtggcatcc atgtcaatta taaacgtgtt ggtagactcc ttcatcagct
     3541 aggtctctat gctaaaggaa gtcgatatca atataaatac tataaccgtc gacgttcttc
     3601 attaactcgt cccaatcttg ttaatcaatg tttccaagcg actggtaaga ataaattatg
     3661 gctaggagac ctaacctaca ttcctacaca agaaggaata ctttatgtgt ctgtctttat
     3721 agacgtttat agtagaaaga ttgttggttg ggcaatgggc cgacgtatgc aagacaagtt
     3781 ggtaacagaa gctttcaatc aagcttataa tagagaaaag cctaaagaag gggtaatcgt
     3841 ccatacagat cagggttctc aatataccgg agcatgattt caggacctac ttagacagaa
     3901 aaaatgtaag tccaggatga gtcgaaaagg taatccatac gataatgcac tcatggaatc
     3961 cttttataaa acattaaaaa gagagcttgt caatgatgct catttcgcaa ctattgagca
     4021 agctcagctt gagattttta aatatagtga gacttactat aaccctaaac gtctgcattc
     4081 agctttaggg tatctctcac ctgttgaatt tgaaaaaata gttactcatt agcttaactt
     4141 tatgtctatt ttttcttgac aagtccaggg tatgaagtcc ctttatacac atactttcaa
     4201 aacagctctc aatcctctgt ccgctacaaa aatacgtcac cgctgccctc cagctgcctc
     4261 attcaacgac aaacttgaag ccacaaacag actcatcaag ggcattaagt acaatgcctt
     4321 tagatttcag aactttgaca actttaaaac caaaatcctc atcgctttga acatccaaaa
     4381 agagagaacc aatctgattc tctctcgttg ttaatgataa gtcacccact acagttgaca
     4441 atgagtctct tacttcctgt ttactcattt aatagctctt ctggttccca agattgatta
     4501 aactcatggt ccttaaaaag agaagccaat cctgttattt gtttcagtct taaaatttca
     4561 tctttatcca ttcctaaatg ttttgcaatc cagttatcac ttcgcccaca ctcatgaaga
     4621 tcctttacaa tctgactcat caaatcaaca tcatgacttc ctctagctct attatgtcga
     4681 atggtagaag ccattcgata gtctaatgac ttatcaataa cagaaacagg taatctccca
     4741 ctttcccttt cataaatatc tgaataatct agcattatac gatatctatg aaaaccatca
     4801 acaatactat accgatcctc ttccttatcg taatagcaaa caatcggcat agtataacca
     4861 tcagatttta tactatcata caataatttc atttcaggcg gagcaactga attcggatta
     4921 taatcatttg gagaaatctt ttcaattgga attgatttaa tctcatagac tggactaata
     4981 aaattactca ctttctaact cctttaaact cgtcttatat ttctctttta aaaaggctac
     5041 tattttttgt tgctctcttg tcaaaccaaa ccccatagtt cgacaaatat gatcgttttt
     5101 taaaatacag aaacacattc gtttccagct tggtatatcc tttgttgtta caatatcgtc
     5161 tgtatcatca ggaatttgat ctaaaaaaat aacccttgaa tgtttaaaag aggtataatt
     5221 tgaaatacca tttctagcaa tacgatatcc tttttcaatt agttcattaa ttgtttcctc
     5281 cgcaagtcct ccgcctgttt tatgccaaaa gtctattgat ttattaaatt ttctaacata
     5341 attatttctt aacctcactg gtagcgttga taaaagaaac tgagtgtacg acttccacga
     5401 atgacccttt ggtaaagcaa ttgatttata tcccattgct ttagtacgtc cataaatatt
     5461 cgaaaagtta actccttgaa cacgtcccaa aagctttacc caagtttctt gatctattat
     5521 tctataaaga tttaggctat caacagcata gtcttgaaaa ggagatgcaa ctctcatttg
     5581 tgatggtttt aaacccgctt tatagaatag atcataaagt tcgttataag aataagaaaa
     5641 cttatagtaa gcatgccata tgtcttccac tgaccaatca tataagggag atgctgtcca
     5701 gacatctttg aattgtttgg taatccagca ttccttttga taaccatact ttttattgat
     5761 aaaaccacta tatctgtgta aggattctga agcacggttt cctaatatac aaactgtttt
     5821 ttgatttccg tgaatttgtt tataccacct accaaattgt ttcgctaaat cctcctgatt
     5881 cattttataa cgataagtag taattgaatt attttccaaa ttaataacat aatcttgaga
     5941 tggcattggt cttacccaga tatcttctgt tttgtcatcc cacggatacc aaaacatttc
     6001 ataactacta agtgcagttc tagtagccat cggtaagcac acccaataca aagaaacttt
     6061 ttttctacct tctaaagaag tgaatgtttc ttgaacatat tttgttgtta aactgtactg
     6121 tgcttcaaaa tcttgatgaa acacacctat ttctctatcc ggataatatt tatctctaaa
     6181 atccagtaaa atattaagaa gtaacccact atcttttcca
//
LOCUS       DAUGQX010000067         5580 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUGQX010000067 DAUGQX010000000
VERSION     DAUGQX010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5580
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.067"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1233
                     /locus_tag="VIA51_001637"
     CDS             <1..1233
                     /locus_tag="VIA51_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8683567.1"
                     /translation="KLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDDESRDAP
                     AGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELLQ
                     YFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGILQNLFPKTSLANDIAGSKA
                     SIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVD
                     PLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKI
                     YHTLYEDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAMSNYIRQKLATIKISKEFTN
                     EHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKIIERLTLKDVVTI
                     GKAFFEKADASDFTVFPK"
     gene            1283..2308
                     /locus_tag="VIA51_001638"
     CDS             1283..2308
                     /locus_tag="VIA51_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8683568.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIVILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2322..2864
                     /gene="pgsA"
                     /locus_tag="VIA51_001639"
     CDS             2322..2864
                     /gene="pgsA"
                     /locus_tag="VIA51_001639"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEQ8683569.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2866..3705
                     /locus_tag="VIA51_001640"
     CDS             2866..3705
                     /locus_tag="VIA51_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8683570.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3681..4523
                     /locus_tag="VIA51_001641"
     CDS             3681..4523
                     /locus_tag="VIA51_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8683571.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREV
                     LKHG"
     gene            4516..5316
                     /locus_tag="VIA51_001642"
     CDS             4516..5316
                     /locus_tag="VIA51_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8683572.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         1814 a          885 c         1037 g         1844 t
ORIGIN      
        1 aaattagaaa atggtttaac tgtttatttt ataaaaaaaa tagggttttt agaaaaaaca
       61 gctatgttga cagtaggttt cggttctctt gacaataagt tgacagtcga tgacgaatca
      121 cgagatgctc cagcaggtat tgcacacttt ttagaacata aactctttga agatgaatca
      181 ggtggagata tttcattaaa gtttacacag ctaggagcag agacaaatgc ctttacaact
      241 ttcaaccaaa cgagtttctt cttttcaaca gctagtaaat ttcaggaaaa tttggaactc
      301 cttcaatatt ttgttctttc tgctaatata acagatgaat ctgttagtag agaaaaaaaa
      361 ataatcgggc aagaaattga tatgtatcaa gatgatgctg actaccgtgc atatagtgga
      421 atccttcaga acttatttcc aaaaacaagt ttagctaatg atattgctgg ctcaaaagca
      481 tccattcaaa agatcacgaa aatattattg gaaacgcatc atacttattt ttaccaacct
      541 actaatatga gtctattcat tgtcggtgat attgatattg acgaaacttt tttagctatt
      601 caaaggtttc aaaccacatt atcctatcca gatagaaaaa gggtaactgt tgatccttta
      661 cactactatc ctgtcattaa atcatcttct gttgacatgg atgttactac tgccaagctg
      721 gttgttggtt ttcgagggta tctgacctta actcagcatt cactattaac gtatcgtatt
      781 gccttgaagc tatttttatc aatgcttata ggttggactt ctaaaatcta tcatacgcta
      841 tatgaagatg gtaaaataga cgattcattt gatgtggatg ttgaaattca tcataatttt
      901 caatttgtat taatatcact tgatacacca gagcctatcg caatgtctaa ctatatccgt
      961 caaaaattag ctactataaa gatatcaaaa gagtttacaa atgagcactt aaatctatta
     1021 aaaaaagaaa tgtatggtga ctttattcag agtttagact ctatagaaca tttaacccat
     1081 cagttcagtc tatacctgtc tgattctgat aaagaaacat attttgatat tccaaaaatt
     1141 atagaaagac tcactctaaa agatgttgtt acaattggaa aagcattttt tgaaaaagct
     1201 gatgcttcag acttcacagt cttcccaaaa tagatgaaaa tctgttataa tagggttact
     1261 atattatttt tgaggtacct gtatgagtga aaaaagtctt ggtgaagtgt taagagaatc
     1321 gcgtgttgga aaaaatatca cactagatga tatagaattg aagacaggga tttcttccca
     1381 ttacttgctg gcaatggaat tggatcagtt taaaattatt ccggaagaaa aatttgatca
     1441 atttttaaaa gaatatgctg acattgttga gttagatttc aatactttaa aaagacgata
     1501 ccgttatcaa gttaattcca aaaaagacag tgatataaaa tctgtaactg agattgttga
     1561 agagaagtta agtaagaaac gattacaaga gaagttgtta tcacatcaga gcatggggta
     1621 tggtcaaccg ttagaagttt ctaaaaacaa agaaacctta gttatccctg taaagactgt
     1681 tggtttagat agcaaatcgc cactaaaaac gatatcgcct gttagccaat ttaaatcaga
     1741 taacaggtta attcctaaaa aaaatgtgtc acgtatgagg cgaaatagca ctgacagtcg
     1801 ttctaaaacg tcactatttc ccatagttat attaggaacg attgcttttg caattatcag
     1861 tgttatcatt ttaggtgttt ggcaacaatt cgaaaagagt caaagagcta aagaagctga
     1921 agttgctttg cttaaagcct ctgagcagtc tactaacggt ttaaaaaata attcaaatga
     1981 tcgcaaaact caagtcacaa ctgaggggtc gggtaattat ttaatagcga ctgttactaa
     2041 atctaaagag accgttgata tcagtgtgtc tttaaccgag gcacaaagta gttggatttc
     2101 tctaacaaat tcagaaattg gtgaaggtgg tataacattg actcaagact cgccaactta
     2161 tacagcgact ttacctgcag aaataacaga atcattgttg acacttggtg tgacaaaagg
     2221 tgtatctgta acaattgatg gacaacctgt tgatctatca cctttaacaa gtactgactt
     2281 aagttatatc acgtttaaga tccaataatt aaggtagact aatgataaaa aaagaaaata
     2341 ttcctaatct attaactctt gttcgaatcg caatgattcc tttctttctt tttattactt
     2401 cctcatctaa taaggtgggg tggcatattt ttgcagctgt gatttttgca attgccagtt
     2461 ttaccgatta tctagatggg tatcttgcgc gtaagtggca tgtagccagt aattttggaa
     2521 agtttgccga tcctctagca gataagatgc ttgtcatgag tgcctttatc atgttagttg
     2581 gacttggctt agttcctgcg tgggtgtcag ctgttattat ttgccgagaa ttggcagtaa
     2641 ctggtcttcg attactactt gttgaaaccg gaggaaaggt ccttgcagct gctatgccgg
     2701 gaaaaatcaa aacagcgaca caaatgttgt ctattatttt attactttgc cattggatat
     2761 tcctaggaaa cgtcttactc tatattgctc tttttttcac tatttattct ggatatgatt
     2821 attttaaagg agcaagcttt ctttttaagg atacgtttaa ataacatgtc agctattatt
     2881 gaacttaaaa aagttacatt taattaccat aaagaccaag aaaaaccaac attagatggc
     2941 gtatcgtttc atgtgaaaca aggtgagtgg ctgtctatca ttggccataa tggatctggt
     3001 aaatcaacga ctattcggtt aattgatgga ttattggaac cagaatcagg gtctattatt
     3061 gttgatggag atctactaac cataactaat gtttgggaaa ttcgtcataa aattggtatg
     3121 gtctttcaaa accctgataa tcagtttgtt ggagcaactg ttgaagatga tgttgctttt
     3181 gggcttgaaa ataaaggtat tgcacatgaa gatataaaag agagggttaa tcatgcttta
     3241 gagttagtcg gcatgcagaa ctttaaagaa aaagaaccag cccgtttatc tggtggccaa
     3301 aaacagcgcg tagctattgc aggtgcagtt gctatgaagc ctaaaattat tattttagat
     3361 gaagctacta gtatgcttga ccctaaagga cgattagagt taatcaaaac tataaaaaac
     3421 atccgtgacg actaccagct gactgttatt tccattactc atgacttaga tgaagttgct
     3481 cttagtgata gagttttagt gatgaaagat ggtcaagtgg aatcaacatc aacaccagaa
     3541 caattatttg caagagggga tgaactactc caattaggtc ttgatatccc ttttacaaca
     3601 tctgttgtac agatgcttca agaagaaggt tatcctgttg actatggata tctcacagaa
     3661 aaggaattag aaaatcagtt atgtcaatta atctccaaaa tgtaagttat acttatcaag
     3721 cagggactcc ttttgaaggg cgtgcccttt ttaacattaa tttagatatt ttagatggtt
     3781 cttatacggc ttttatcgga catactggat ccgggaaatc gaccattatg caattgctaa
     3841 atggtttaca cgttccgaca acgggaattg tcagcgtaga taaacaagat ataacgaatc
     3901 actctaaaaa taaagagatt aaatctattc gaaaacatgt aggattagtt tttcaatttc
     3961 cagaaagtca actatttgaa gagacagttt tgaaagatgt tgcttttggc cctcaaaatt
     4021 ttggggtctc tccggaggaa gcagaagctt tagcgcgtga aaaactagct cttgttggga
     4081 tttcagaaaa tctttttgaa aagaatccat ttgaactctc agggggtcaa atgcgtcgtg
     4141 ttgctattgc gggtatcctt gctatgcagc caaaggtttt agttttagat gaaccgactg
     4201 ctggtcttga tcctaaaggg cgtaaagaat taatgactat ttttaaaaag ttacaccaat
     4261 ctggcatgac tattgtttta gtaacccatc tgatggatga tgtggccaat tacgcagatt
     4321 ttgtatatgt tcttgacaaa ggtaaaatta ttttatcagg aaaacccaaa acaatttttc
     4381 aacaagtcag tttgcttgag aaaaaacagt taggagttcc taaggtgact aaacttgctc
     4441 aaaggcttgt tgatagagga atacctatct cttctttgcc tattacctta gaggagctaa
     4501 gagaggtact aaaacatgga taagctgatt cttggtcgtt atattcccgg agattctctc
     4561 attcatcgtc ttgacccaag aagtaaatta ttagcgatga ttatttatat tgtcattatc
     4621 ttttgggcta acaatgttgt gacaaatttg ttgatgttga cttttacttt agcagttgtt
     4681 tttttgtcaa aaatcaagtt gtctttcttt ttaaatgggg ttaaaccaat gattggtatt
     4741 atcctcttca cgactttatt tcagatgttt ttctcacaag gaggaaaagt aatttttagt
     4801 tggtggttca ttagcataac tgatttagga ttgagccaag ctattttaat ttttatgcgt
     4861 ttcgttctaa ttattttctt ttcaacgctg ttaacgttga cgacaacacc tttaagccta
     4921 tctgatgcag ttgaatcatt attaaaacct ttaacaagat ttaaagttcc agctcacgag
     4981 atcggactaa tgctttcttt aagtttacgt tttgtgccta ctttaatgga tgataccacg
     5041 cgtattatga atgcacaaag ggcccgtgga gttgattttg gagagggaaa tttaattcaa
     5101 aaagttaaat ccattattcc tattttaatc cctcttttcg cttcaagctt taaaagagcc
     5161 gacgcattag ctattgctat ggaagctaga ggttatcagg gaggagaagg gcgaactaaa
     5221 tatcgtcaat tagactggca gctaaaagat agtttagcta ttggaatagt ttctttattg
     5281 ggtttgctac tttttttctt gaaaacctct ttgtaatatt ttttagcaca aaacttttct
     5341 ttattagtaa gaagtgaatt gtacctcaaa agttagatac aatatctaat gattgaggta
     5401 cttttcttca tttgaggaat tgaaaaccgc tatctcaact atattaatcc tcccaataat
     5461 aacaaatcga acgaaatcta aaaggactga gtcctgttca atacagaact aaattcttag
     5521 tttaatgata ttatcccgct ttttaatgtt gctaagaaga agagttttat gattttttac
//
LOCUS       DAUGQX010000068         5384 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUGQX010000068 DAUGQX010000000
VERSION     DAUGQX010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5384
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.068"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            73..594
                     /locus_tag="VIA51_001643"
     CDS             73..594
                     /locus_tag="VIA51_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8683573.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            809..1327
                     /gene="rimM"
                     /locus_tag="VIA51_001644"
     CDS             809..1327
                     /gene="rimM"
                     /locus_tag="VIA51_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEQ8683574.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DRFVQEVTIVSHRKQKHFDIIKFKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYH
                     QIIGMAVYEKDVLIGHVKEILQPGANDVWIVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            1317..2048
                     /gene="trmD"
                     /locus_tag="VIA51_001645"
     CDS             1317..2048
                     /gene="trmD"
                     /locus_tag="VIA51_001645"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEQ8683575.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLKKTYLRRPDLL
                     EHYNFSEEERKLLDKIKEALDQGED"
     gene            2048..3040
                     /locus_tag="VIA51_001646"
     CDS             2048..3040
                     /locus_tag="VIA51_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8683576.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            3218..4276
                     /locus_tag="VIA51_001647"
     CDS             3218..4276
                     /locus_tag="VIA51_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEQ8683577.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            4289..5212
                     /locus_tag="VIA51_001648"
     CDS             4289..5212
                     /locus_tag="VIA51_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEQ8683578.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     VVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQV
                     ADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
BASE COUNT         1707 a          862 c         1145 g         1670 t
ORIGIN      
        1 gttaaaatac aattactata accaaaaatg agcacctgtt caatagtgaa caacatttag
       61 aaagtgtccg atatgacaaa agacagacaa atcaaaaaaa caaaaacagc tatctatagt
      121 gcttttattg ctttattaca aaaaaaagaa tattcgaaaa taactgttcg agatatgatt
      181 acacttgcta atgtagggag atcaaccttt tatgcacatt atgaaagcaa agaaatgtta
      241 ctaaaagaac tctgtgaaga actttttcat catttgttta ggcaaaaaag aaatgtgact
      301 tttgaggact atttggtaca tattttaaag cattttgaac aaaataaaga cagcattgcg
      361 acgttgttac tttctaatga tccctatttt ttattaagat ttaaaaacga actagaacat
      421 gatgtttacc ctaacttgcg ctgcaagtat atcgacaaaa cgactattcc agaagtattc
      481 ctaaaacaat ttgttctatc tagttttata gaaaccttaa aatggtggct ccatcaaagg
      541 caaaggatgt ctgcaaatga actattaaag tattatttag agctcataaa ataatgacta
      601 gtgagtcatc ttgccaaatt caatttttta atacagacgg attttaacaa tttaacagat
      661 aaagacaaaa ctgtaagtgc aaaatagact ataacgtgat aaaataatag gtaatttggt
      721 tctgaaaaag aagtgtctat caaactttag aatcaagaga ggtcgctaaa gtgacgtgag
      781 ataaagagtt aacgatttag gagctaccat ggaatatttt aatgttggaa aaattgtcaa
      841 cacgcaaggc ctgcaaggag agatgcgcgt gttgtctgtc agtgattttg ctgaggaacg
      901 ctttaaaaaa ggctcacaat tagctttatt tgatgataaa gatcggtttg ttcaagaagt
      961 gacaattgtt agtcaccgta aacaaaagca ttttgatatt atcaaattta aagacatgta
     1021 tcatattaat gctattgaaa agtacaaggg atacacttta aaggtctcaa aagacaatca
     1081 aggggattta caagaaggag aattttatta ccatcagatt attggcatgg ctgtttatga
     1141 aaaggatgtc cttattggac atgttaagga aatcttgcag ccaggtgcta atgatgtttg
     1201 gatagtgaaa cgccaaggaa aacgagactt gctcttacca tatattcccc cagtagttct
     1261 taacgtagat gttcctaaca agcgcgtgga tgttgaattg atggaaggct tagacgatga
     1321 agattgatat tttaaccctt tttcctgaaa tgtttgcccc tctagagcat tccattgtag
     1381 gcaaggcaaa agaaaaaggt ctgttagaca ttcactacca taactttcga gattatgctg
     1441 aaaaagctcg tcatgtggat gacgaaccct atggtggggg ccaaggcatg ttattgagag
     1501 cgcagcccat ttttgacacc attgaacaga ttgaagccaa aaaaccaagg attattcttt
     1561 tagatccagc aggtaaaccc tttactcagg cttatgctga agaattagct cttgaggaag
     1621 agttaatttt tatttgtggt cattatgaag gttatgatga gcggattaag accttggtga
     1681 cggatgaaat ttcattaggc gactttgtat taacaggagg tgagttggcg gccatgacta
     1741 tggtggatgc gaccgtcagg ttaattccac aggtacttgg gaaagaaagt agccatcagg
     1801 acgattcttt ttcatcagga cttttagaat accctcaata cacaagacct tatgattatc
     1861 gtggtatgac agttccagat gttctaatga gtggtcatca cgaacgtatt cgcttgtggc
     1921 gtctagaaga aagtctcaaa aaaacttatt taaggcggcc agatttactt gaacattaca
     1981 atttttccga ggaagagcgc aagctattgg ataagattaa agaagcattg gatcaaggag
     2041 aagattagtg aaagataaag catatgatat tacgattatt ggtggtggtc caataggttt
     2101 atttgcagcc ttttatgcag gtcttagggg cgtaacagta aagattattg agagtttgtc
     2161 agaacttggt ggacagcctg ccattcttta tcctgagaaa atgatttatg atattccagc
     2221 ttatccatct ttaacaggtg ttgagttgac agaaaattta ataaaacaat tgagccgttt
     2281 tgaagatcgt acaaccattt gtttaaaaga agaagtatta acctttgaca aggttaaagg
     2341 tggtttttcg attaggacta ataaggcaga gcatttttca aaagccatta tcattgcttg
     2401 tggaaatggc gcttttgcac caagaacttt agggttagaa agtgaggaaa actttgctga
     2461 tcataacctt ttttataatg ttcaccagtt ggaccagttt gcgggacaaa aagttgtgat
     2521 ttgtggtggt ggagattcag cagttgattg ggctttggct ttagaagata ttgctgagag
     2581 tgtgacggtt gtgcaccgtc gtgatgcttt cagagcacat gaacacagtg tggaattatt
     2641 gaaagcatca acggtcaacc tcttaacacc ttatgtgcca aaagcattga aaggaattgg
     2701 aaacctggct gaaaaattag ttattcaaaa agtgaaagaa gatgaagtgt tagaacttga
     2761 attggacagt cttattgtta gttttggttt ttcaacttct aataagaatt tgaaaaattg
     2821 gaatctcgac tataagcgtt caagtattac tgtttcacca ctttttcaaa caagtcaaga
     2881 aggtattttt gccattggtg atgcagccgc ttataatggg aaagtggatt tgattgctac
     2941 tggttttggc gaagcaccaa cagcagttaa tcaggccatt aactatattt atccagatcg
     3001 agataaccgt gtggtgcatt caacctcttt aattgactaa gggagtcgga agtttcaaga
     3061 gcagtagcaa cagctaatat tcagtttgtc aggagaggac aaatggtttt tacctaagtc
     3121 ttcgtgacaa gttttatact ttgtgataaa atagtcattg tgaaaaaagt gtgatggttt
     3181 tcacagatta acacattaca atgaaaaggg gtctatcatg acaacaacag ataaagagac
     3241 atttagttct tttatgaata aggtcttggc tggtacagcg attgctatcg ttgtggcact
     3301 cattccaaat gctattttag cgactttctt aaaaccgctt ttgccaaata tggcagctgc
     3361 tgaattttta cacattgtgc aagtcttcca attcttcacg ccgattatgg ctggtttctt
     3421 gattgggcaa caatttaagt ttaatcctat gcaacagttg gctgttggtg gagctgctta
     3481 tatcggttct ggagcctggg cttatacaga agtcattcaa aaaggtgtgg cgacaggaac
     3541 attccaactt agaggtattg gggacttaat caatatgatg attacagcta gccttgcggt
     3601 tttagctgtg aaatattttg ggaataaatt tggctcttta accattatct tgttacctat
     3661 cactatagga actggcgtag gttatattgg ttggaaattt ttgccttatg tgtcttacgt
     3721 gacaaccctg atcggacaag ggattaattc ttttacaacc ttacaaccta ttttaatgtc
     3781 tattttaatt gcagttgctt tctcgcttat cattgttagt ccgatttcaa ctgttgcaat
     3841 cggtttagct attgggctta atggaatggc tgcgggagca gcttctatgg gaattgcatc
     3901 gacagcagca gtcttagtgt gggcgacgct taaagttaat aaatctggtg taccaattgc
     3961 tatcgcactt ggggctatga aaatgatgat gccaaacttc ttgaaacatc ctatcatggc
     4021 tattccgatg gtgttcactg cagcaattag ctcattaaca gtaccattgt ttaatcttgt
     4081 tggaacacca gcttcatctg gttttggctt agttggtgca gtaggtccga ttgcttcttt
     4141 agcaggtggt agctcaatac ttattattat ccttgcttgg atcattgttc cgtttgcggt
     4201 tgcttttgcg gcgcataagg tttctaaaga tattctaaaa ctgtataaag aagacatttt
     4261 cgtctttgaa ggctaatagg aggaaaatat gttagtttat attgctggct caggagccat
     4321 ggggtgccgt tttggttacc aaatttcaaa aacaaataac gatgtgattt tgttagataa
     4381 ctgggaagat catatcaatg ccattaaaga aaacggttta gtggtgacag gggatgtgga
     4441 agaaacagtt aagcttccta ttatgaaacc gactgaagcc actcaagaag ccgatttgat
     4501 tatcttgttt acaaaagcaa tgcagttgcc acaaatgctt caagacatta aaggcattat
     4561 tggaaaagaa accaaagtgc tttgcctttt aaatggtctt ggacacgaag acgttattcg
     4621 tcagtacatt ccagagcaca acattttgat gggggtcact gtctggactg ctggtctaga
     4681 aggtcctggt cgtgctcatc ttcaaggtgt gggagcactt aacttacaaa gcatggatcc
     4741 aagcaatcaa gaagctggac accaagtggc tgatttgtta aatgaagcta acttgaatgc
     4801 gacttatgat gagaatgttg tgccaaacat ctggcgaaaa gcttgcgtga atggtaccat
     4861 gaactcaact tgtgcccttc tagattgtac aattggtgaa ttatttgcca gtgaagacgg
     4921 tctcaaaatg gtaaaagaaa tcatccatga gtttgttatc gttggtcaag cagaaggtgt
     4981 cgaactaaac gaagaagaaa tcacacaata tgtaatggat acatctgtta aagctgctca
     5041 ccattaccca tcaatgcacc aagaccttgt gcaaaatcac cgattgactg aaattgattt
     5101 tatcaatggt gcagtcaata ccaaaggtga aaagcttggt atcaatactc catactgccg
     5161 tatgattaca gagctagttc acgctaaaga agcagtgttg aacatccaat aaacgctatc
     5221 aaatcgttat actcaatatt atggctaaag ctttaatatt gagttttttg ttatgctgat
     5281 agtatttttc ttaggcgtca ttatttgtga gcctagatta tgagttaata aaagaaataa
     5341 taattggtag aatttgatag attttgaaag gttatgcttg actt
//
LOCUS       DAUGQX010000069         5331 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUGQX010000069 DAUGQX010000000
VERSION     DAUGQX010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.069"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(246..560)
                     /locus_tag="VIA51_001649"
     CDS             complement(246..560)
                     /locus_tag="VIA51_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683579.1"
                     /translation="MPRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNGNL
                     SIDTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVR
                     ID"
     gene            complement(626..1078)
                     /locus_tag="VIA51_001650"
     CDS             complement(626..1078)
                     /locus_tag="VIA51_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8683580.1"
                     /translation="MGLLDLIGRKRARDKPQNSYEGQDFSYLFGRTTSGENVDEFKTM
                     QTTAVYACVRVLAEAVASLPIHIYERTENGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TIMSHLLIWGNAYVQIIRDKSGMVSLLLKQKASVLIRKLLLIIWQRMP"
     gene            complement(1183..1455)
                     /locus_tag="VIA51_001651"
     CDS             complement(1183..1455)
                     /locus_tag="VIA51_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683581.1"
                     /translation="MELVKTIQIGDDIYPPIPDLFGIQENQEFNLYKSTDGTLVLSPS
                     DSKLSADHQSISSDEQMTTAVEQARLDEIATSVLSRHLDAFKELTE"
     gene            complement(1474..1779)
                     /locus_tag="VIA51_001652"
     CDS             complement(1474..1779)
                     /locus_tag="VIA51_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8683582.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADDLLERLSQGM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(1779..2081)
                     /locus_tag="VIA51_001653"
     CDS             complement(1779..2081)
                     /locus_tag="VIA51_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEQ8683583.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLFQLKENA"
     gene            complement(2136..2312)
                     /locus_tag="VIA51_001654"
     CDS             complement(2136..2312)
                     /locus_tag="VIA51_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ8683584.1"
                     /translation="MGQNVVMRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCICRQG
                     DEASVYDERGILSF"
     gene            2328..3221
                     /locus_tag="VIA51_001655"
     CDS             2328..3221
                     /locus_tag="VIA51_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683585.1"
                     /translation="MTNMLDFPYHHEFIEFLGRWTHILIALPKRHHGQVDTAIPRYLL
                     VTIREKTGIVKLTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEALNLIALCPDGFLTYQADRRKKIVTTLKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYNISYDSKQLTDKISPENNRTLYQLVKNQVI
                     DNYLTIQKIIVNLDKQGKIDYEKIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHLATL
                     QDIYFCQMIVSYFIQKCEVLE"
     gene            3221..3445
                     /locus_tag="VIA51_001656"
     CDS             3221..3445
                     /locus_tag="VIA51_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683586.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSRNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            3436..4164
                     /locus_tag="VIA51_001657"
     CDS             3436..4164
                     /locus_tag="VIA51_001657"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEQ8683587.1"
                     /translation="MLIEMWSPVFKKHGEIREPICFHHGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARRYAFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDI"
     gene            4249..5094
                     /locus_tag="VIA51_001658"
     CDS             4249..5094
                     /locus_tag="VIA51_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEQ8683588.1"
                     /translation="MDISIEFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLETI
                     LDSEFSTERESLIAEIDELESQLTTLNQELQELGNIPNLSSEYLENYSKLTATINALK
                     EQNEAYLKESGLSKEKSETDADLKRSTEDILLDLEVKINSKMREVNNILYPDIRKAPQ
                     INLNAHNSYSFYTPDDDGTGTKFKGMIVFDLVMLYLTNLPALAHDSLLLSNVSYQATE
                     ALLKLYDQSRSLNKQVFLVFDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGE
                     NSDEI"
     gene            5084..5293
                     /locus_tag="VIA51_001659"
     CDS             5084..5293
                     /locus_tag="VIA51_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8683589.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
BASE COUNT         1731 a         1121 c          909 g         1570 t
ORIGIN      
        1 agtattaaaa ttcccactca aactcctagt ccctttgttt caagctattt agaactttta
       61 ttgtattatc cactttattc ctatttctgt tgctattagt tttatcatac aatctaacct
      121 ttaccctttt tagggagtgc aaaattcaaa tgaatcgtgc atctcaactc ccaatataac
      181 ttctttcatt ataccacaga taaactaaaa aaggacgtgc cgaattgata cgcccttgcc
      241 ttttatcaat caatccgtac gccatttttg aaggttaggc tgatgtgctt gtctactttt
      301 atatccaacc tttcaacact tgtctgccag agttctccct ttggaccagg agttaaagag
      361 atggttgtaa ggtcagcttg tgtcgctaga ctttcccctc tcacctttag gagcggtgtg
      421 tcaatggaaa gattcccatt cccatcccta tcccaactaa agactggagt attctgtcct
      481 ggaataacga ccttatcagc ttcaacttct aggctcttca catactctga tagaatctgt
      541 tgggagataa gccttggcat ccatgctgaa ctagagacgg tcaactcatc aatcttagct
      601 ttgtgaagtg ctgcaattcg tgcttctaag gcatccgttg ccagataatc aagagcagct
      661 ttcttatcag aacgctcgcc ttctgcttta gcagtagcga taccatacca cttttatctc
      721 gtataatctg tacataggca tttccccata tcaaaagatg gctcatgatt gtctctcgaa
      781 agataaagga ggacatctct ggattgggtt catcatgaag aagaaagtac agtgggtggt
      841 ccagcttttt ctccttccca ttttctgtcc gttcatagat gtgaatagga agtgacgcca
      901 ccgcttcagc aagaacacgc acacaggcat agactgccgt cgtctgcata gtcttaaact
      961 catccacatt ctcgccacta gtcgtgcgac caaagaggta ggaaaagtcc tgaccttcat
     1021 aactgttttg gggcttatct ctagcccttt ttcttccaat taaatcaagt agtcccataa
     1081 gccctcctta ttttggggta caaaaaaagc acctcctttg aagtgctttc ggtatatttc
     1141 tttcaaagta atcaacagtc tttcttacaa aacctagtat tctcattctg tcaattcctt
     1201 aaatgcgtca agatgtcgtg ataatactga agtcgcaatc tcatctaacc ttgcttgttc
     1261 aacagctgtt gtcatctgct catcactgct tatactttgg tgatccgctg atagtttgct
     1321 atcagatgga cttaacacca aagttccatc agttgattta taaaggttaa actcctgatt
     1381 ctcttgaatg ccaaataggt caggtatcgg aggatagatg tcatcaccaa tttgtatcgt
     1441 ctttacgagt tccatacatc actctccctt actttaccaa ttattcatat gacgtgatcc
     1501 atagacgacc gcaacaatta taacttcatc ttccagaaca tgatatacaa tgcgatattt
     1561 tttgacaatc agttgtctga aggtatagcc ttttccaatc agatcctcaa tgatggcaca
     1621 acgttcagga aaaatggata gtgataacat tccttgggat aacctctcaa gaagatcatc
     1681 cgctgcctgt ggtgcacaga gttcatcacg aacatagtga tagatgctca gcaaatctgc
     1741 tttagcatca tccgacatgg tgacctgata ttctttcatt aagcattttc cttcaattga
     1801 aatagaaatt ctctgacatc ctgacggttg ccagttttcg catcttcaaa gctggtgata
     1861 agcttatcat aaaacttctc ctgactcatg taatcaacat taactcgttg aggcgcttca
     1921 ggtagagaaa catcaaatgg gataccccca gtcaaaataa tctgattcaa aaacatatca
     1981 atcgcagttg acataggaat acctaagcgt ttcaaaatat catctgccgc actttttact
     2041 gaatcatcaa ctcgtaaatt caaagttccc gttttagcca tggttatcct ccttttttgt
     2101 aacgacattg tatcacgttt ttagagttga ctcaactaaa aactcaatat ccctcgctca
     2161 tcatagacgc tagcttcatc accttggcgg caaatgcaac ggtcaagccc caggataaga
     2221 cctacaatac cgtcaatctt ctcaacagat ttttccttat ctggcttgat gttgcctcca
     2281 ggggcttgtc gcatcaccac gttttgtccc atccatttaa ggactggatg accaacatgt
     2341 tagattttcc ctaccatcat gagtttatag agttccttgg acggtggact catatcctta
     2401 tagccctgcc caaaaggcac catggtcaag tcgacaccgc aattccaagg tatcttctgg
     2461 taaccatcag agagaagaca gggattgtaa aattaaccac tgtgcaaaat acagcgttca
     2521 ctacccagtc gaatcaactc aaaaaacaat acgggcagtt cttgttaaca gaatctaata
     2581 actgttgtgc atgcccaggc tgtgatagac cactcattct aaccagtggc aacttagcag
     2641 cagaaaatta cgaggtttca gccattgaaa aagataagga cgctgaagca ctgaatctga
     2701 tagccctctg cccagatggt tttttaacct atcaagcaga taggcgcaaa aaaattgtaa
     2761 caactctaaa aaatgttaaa aagattctag tctctgcaca taacagccaa caagcgattt
     2821 ctgatatgaa gttagacagt ggaattgttt cagttttgac tagtctcaat aaactaaaat
     2881 gtgatgaata taatatctcc tatgactcga agcaattgac tgataagata tcacctgaga
     2941 acaatcgtac gctttatcaa ttggttaaaa accaagttat tgataactac ttaaccattc
     3001 aaaaaatcat cgtaaatttg gacaaacaag gaaaaattga ttacgagaaa atccaatatc
     3061 aaacgcgatc gatgtataaa aagttaaaag cagccaagca taataatctg gctattttca
     3121 atactatttc ggaaaaactc catctggcta cactacagga catctacttc tgtcagatga
     3181 ttgtctctta ttttatccaa aaatgcgagg tacttgaata atgcaattac caaataaact
     3241 ttactcctat caaaaaagca cccttgctta tttgcctaga gtgctaaatg aaatcaaaag
     3301 tagaaactca aacgtcaaag atatctttca cgctatctca gaagagttgg atgatcctac
     3361 agattttcta tccataatgg attgcttgta tgcattgaac gctattgaaa tgtctaatga
     3421 aggagaagta aaattatgct tatagaaatg tggtctccag tatttaagaa acacggagaa
     3481 attcgggaac caatctgctt ccaccatggg ttaaacgtga ttatggggat ggatttagct
     3541 gataactcta tcggcaaatc ctcctcacta ttagccattg atttcatctt tggaggtaat
     3601 agctatctaa aatcaattgc ggttaaaaaa ttaggtgatc atcctatcta cttctgcttt
     3661 caatttgaga aaaagtttta tttttcaaga gatacggcca acccagatat cattctagtg
     3721 tgtgacaaga gctactctcc aaccggtgaa acaatggacc taggaatttt tcttaacaaa
     3781 cttaagaaac gatatcattt agattctcca gagctatcat tccgattagc tatgagtggc
     3841 ttctttagga ttgcaggaaa aagtaatcaa aataccgatt tccccttaca agtttattcg
     3901 agccaaaaat cttctgaatc tattactact ctcatccaac tgtttaattt gtatgataac
     3961 attgcacgat acaaagaacg tctgaaagat aagagcgacc agttaacaac ttttcgtaat
     4021 gctcgcaggt atgccttcat ctccaacctg gttggcggta aaaagcaatt tgaagcaaat
     4081 gtctcagaaa taaaaagatt ggaatatgat ttagcacatc tccaagatac tcatcaagat
     4141 aaaattgact ctgatgatat ttaaaaaaat caacaaaaac tccaacttag aaatactaag
     4201 ctggagttag aaagcagtct tcgggacaag caaagacgtc ttaagctatt ggacatcagt
     4261 atcgaatttg gcttatatcc tactgaatct gacttaacag agcttcaaca atacttccca
     4321 gatactaatc tcaaaaaatt atatgaagtt gaagcttacc acaaaaaatt ggaaactatt
     4381 ttagattccg aattctcaac tgaacgtgaa tccctaatag ctgagatcga cgaattagag
     4441 agtcaattaa caactctaaa ccaagaactt caagaactag gaaacatccc aaatctttca
     4501 agtgagtact tagaaaacta ctctaaacta acagctacaa tcaatgcact aaaagaacaa
     4561 aacgaggcct acttaaagga gtctggtcta tccaaagaaa aatcagaaac ggacgctgac
     4621 ttgaaacgca gtacagaaga tatccttcta gatctagaag taaaaatcaa cagtaagatg
     4681 cgtgaagtca ataacattct atatccagat attcgcaaag ctcctcaaat taacctaaat
     4741 gctcacaata gctactcctt ctatacacca gatgatgatg gtacaggaac taagtttaaa
     4801 gggatgattg tattcgactt agtaatgctc taccttacta atctgccagc actcgcacac
     4861 gattcattac tcttgagtaa tgttagctac caagcgactg aagcactttt gaagctatat
     4921 gaccagtcaa ggtcattgaa caaacaagtc tttttagtct tcgataaagc cagctcttat
     4981 tctccagatg ctaatcaact cttgtcagaa aatacggtat tgagactctc tagtaacgga
     5041 aatgaactct acggtatttc atggaacaaa ggagaaaact cagatgagat ttagttacaa
     5101 taaattatgg aaacttctta ttgataaagg ttggaccaaa acaaagctca ggcaagaagc
     5161 tgggattagt tcttccacga tcgcaaaatt gggaaaaggg gaaaatatca ctactgatat
     5221 tttattggaa atttgtattg cacttgattg taagattgaa gatatagtag aaattgtaga
     5281 taataatatc tagaaataaa aaaagcacta agttgataag atgtgtaagt c
//
LOCUS       DAUGQX010000070         4864 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUGQX010000070 DAUGQX010000000
VERSION     DAUGQX010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4864
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.070"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(83..325)
                     /locus_tag="VIA51_001660"
     CDS             complement(83..325)
                     /locus_tag="VIA51_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8683590.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMRDILDYLVQRLT"
     gene            complement(318..1325)
                     /gene="plsX"
                     /locus_tag="VIA51_001661"
     CDS             complement(318..1325)
                     /gene="plsX"
                     /locus_tag="VIA51_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEQ8683591.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            complement(1428..2183)
                     /gene="recO"
                     /locus_tag="VIA51_001662"
     CDS             complement(1428..2183)
                     /gene="recO"
                     /locus_tag="VIA51_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEQ8683592.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            complement(2369..3331)
                     /locus_tag="VIA51_001663"
     CDS             complement(2369..3331)
                     /locus_tag="VIA51_001663"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8683593.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEIGN"
     gene            complement(3584..4780)
                     /locus_tag="VIA51_001664"
     CDS             complement(3584..4780)
                     /locus_tag="VIA51_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8683594.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALRLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
BASE COUNT         1533 a          997 c          746 g         1588 t
ORIGIN      
        1 atttacgttt ataagttttt ttaaaaaaag gttcgttttt aaagaataat aaaaagagct
       61 tacgctcttt ttattattct aactaagtca aacgctgaac taaataatct aaaatgtctc
      121 tcataaatac catatcctca acatcttcat caggaatagc aatatgaaat tcatcttcaa
      181 cattaataat aaattcaact agttcaatag agtcaaccgc taaatcattt tttaaatgtg
      241 tttgttctgt aatagctaca ctcaaatagc ttctttgctt ctgaattaag ttaatcagcc
      301 tttcaaaaat ctcctgtcta gtcatttact tgagtctcct tagcaaattc ttctactaat
      361 tgtccgacca cgttagtgtc tagcatcgta cgtacttgtt ttatcgttga aaaaatagct
      421 tttacatcac tagaaccatg agactttaca acaggtgcct ttaaaccaaa taaaactgca
      481 cctccagcac tagagtagtc aagagtcttc ttcatctcgt aaagactact tttaagtaga
      541 ctagctccaa ttttagtctt aataccgccg ctattaatta tctgtttcag ttgccccata
      601 atgctaatag ctgttccttc tattgatttc aacactgcgt ttcccgtgaa accatctgat
      661 acaataacat ctgcaacacc tgacataagt tctcgcgcct cgacattacc aacaaaagat
      721 attgtattat ctgctgttaa aagttcataa gtggccttac gaaggggatc tccttttgtt
      781 tcttctgtac cattgtttaa tagaccaaca cgtggattag caatcccacg tacattctta
      841 gcatagaaag agcctaaaat agcatattga tgtaaatgtt ttgccgtatt ttcagcatta
      901 gctccaagat ccaacatatc aaatcctaat ccggttactg tgggaatagt tgataataat
      961 cctggacgat caactccctt gatacgcccc acaacaaaca aacctacagc taaaagagca
     1021 cctgtattcc ctgctgaaat aatggcatct gcttttcctt ctttcactgc cttagctgct
     1081 aaaaccattg aagccttctt tttacggcga acagcttttg caggttcatc atctgacata
     1141 attttttcat ctgtatgaat aatagcaaca cgatctgatt gaataagata ggagttaatc
     1201 tttgtctgat caccgtaaag ttgaatttcg atatctgaaa atgcttctat tgcttgatta
     1261 acaccctcaa caatagcttt aggagcgtta tctccaccca tagcatctat tgcaattctc
     1321 ttcatttcca ctcctttaat tatatcttgt gttcttacac aatctattaa taatattttt
     1381 attatagcat attctgaaac caattcccat aaacgaaaga gaccctatca tttcataata
     1441 tctccccact taactaaatt atcaatgaat gttttacttt ttaatttgat tcctacatag
     1501 tcgtgataca actcatcaat gaactgacga agcttctttt tgatgtcttt attcaatgaa
     1561 atagttctca aatcatcaaa tgtgattttt tgaaatcgac tcaacaagta gataacattt
     1621 ggatctaaat gattacgtcg gttgtctttg taataatgtt cagaacaaag tacagctgaa
     1681 aaacgatggg aaaaatcaag cggtaaatca gtgcgatgac aaatggcaca ctcatgaaag
     1741 tttagactaa taccaaaacg atctaatatc tgaatttcaa aaatatttgt caaaatttca
     1801 taatctaggc cctcttccat caaatcaagt gtttttttca aaaacgtaaa caaatgcgaa
     1861 tctgattcat tatctgcaat cgcagcatca gctaatgcta agacataact agcataggct
     1921 aatcgaaaaa tatcattatt aatataccga taagtgttaa cgttactata gtcaacaaca
     1981 taagacaagc ctgtatcatt taacttgaaa ataaaatcag caatcgttag tggttgaatg
     2041 attgaggaca ttttggaacg actaatatgt ttcacgaaaa acatctgctt acctgctact
     2101 tcagtaaata ttttgactaa tttatcatct tctcgataat tcctattaaa aagaacgatg
     2161 cctagtgatt ctgttagttg catattacct cgtcgtattt ttctcttacc ttttatctta
     2221 gtttacaata aactgttgtt atctttctta ttatacccaa aatcctttag aattgcatag
     2281 ttcatcccac aataattaat accacattac ccttacattt tattcaagtc aaaaagcccg
     2341 agatctatta tctcaggctt cgttaagttt aattgcctat ctcaaataaa ggtgacaacg
     2401 gacgtttttc atgaatacga ataatcgctt ctgcaaccaa atcagcaatt gaaatttgtt
     2461 caattttatc aataaggcgt tcttttggca gataaatagt atcaagaaca attagttttt
     2521 cgatagccga acgttgaata ttatcaagtg ctggtccaga aagaacggga tgcgtacatg
     2581 acgcatacac agctgttgcc cccgcttcag caagcgcatc tgctgcatgg caaatagtcc
     2641 ctgcggtatc aatcatatcg tcaatcaaga tacatttctt ccccgaaaca tttccgataa
     2701 tattcatcac ttcactggtg ttcatcttat ccacactacg acgcttatcg ataattgcaa
     2761 ttggtgtttg gaggaattgt gctaatttac gcgcacgagt cacaccacca tggtcaggac
     2821 taacaacgac aacatcttca cccactaaac catgacgatc aaaatagtct gcaattaaag
     2881 gtgcacccat caagtgatca actggaatat caaagaaccc ttgaatttga gcagcatgta
     2941 aatcaaccgt taataagcga tctacaccag caacttctaa catattagca actaattttg
     3001 aagtaatagg ttcacgagaa cgcgctttac ggtcttggcg tgcatagccg tagtaaggca
     3061 tcacaactga aattttttca gcactagcac gctttaaagc atcgaccata atcaaaattt
     3121 ccattaaatt atcattgaca ggtgagctag ttgattgcaa aataaagaca tgatgaccac
     3181 gaattgattc ttcaatattt acttggattt caccatctga aaactggcga accgtagact
     3241 ttccaagttg aatacccatt gcagacgcaa ctttttctgc taattccttg tttgacgata
     3301 aagcaaacaa ttttaaatca gaataagaca ttttttcctc caaagtttta atcctatacc
     3361 attttaacgc ttttcaagtg aattatcaaa tgaaattgaa aaaccgttaa agaatgtatt
     3421 aaatatacct tttatcgact ttatatactt ctcttatatt atacataagc gattggccaa
     3481 acaactctct tataaattaa ctatatcgtc aatactctca gaactattcc acaataggag
     3541 taatcaaaaa ggttagaaca actgttctaa cctaaataat atgttagtgt ggataaataa
     3601 atgtaacacc tgttggatta aaccagccac ggtggtcagc aatgtactgt ctaccactgt
     3661 agttagactc catcacacga atacttgagg cactttgaac ctcaactaca acggcgacat
     3721 gtccataacc accatcgttc caaacggcaa tcgcacctac catcggcgtt gaaccagtac
     3781 gataaccagc tgcttgagca ctataagccc attgaccacc atttccccaa ttatttcctg
     3841 cccaaggagc taaagattta gctccccatg tgcattgtcc aactggataa gtattagaag
     3901 aatcatatga tgtttgtggt cctgcagaag gagctgccgg agccgtgagt gcagctggtt
     3961 caatagcatt actactttgc gctgccggag tagcttgtgg tgctggagta atagcagatt
     4021 ttgctgcttc aacagatgct gcttgttgtg cagcctgttc ttgtgcctta actttagcag
     4081 cctgttcttg tgctaaggct tcagcagcag ctttttctgc agcttctttt tgagctacca
     4141 aattagcttt atcttcagta gcagatgcta atcggagagc taaatttgca gttgcagcta
     4201 ccaaattagc ttgttgagta cgtaatgtat tttggttttc ttcagccatt gccatattag
     4261 cggcaatggt attaatagct gtttggttag cagcttgctt ttcttcaagg gaaactttat
     4321 cagctttttg ttgttctaac aatttagcgt tagcagagac agctctatta attgctacta
     4381 aacggtttac aacatcagaa attgatttag aattcaaaag tgcattaata taaccagaag
     4441 tttcattgtt tttataagca ctacgagctt gattttttaa tttttcatta cgagcaacaa
     4501 tttgacttgt tagagcctta atttcttgct caaatcgctt tgaaagcgcc tcaagttctg
     4561 tatttcttgc ggtcagttta tcttgttcag attgtagtga acttacttga gcctgtaacg
     4621 ctgaaacttg attctgtgca gctttttgct ctgtagtcag atttgagata atagaatctt
     4681 gcttagcaat cttagtactt aaatcctccg ctcctacagt tgtagctgct ccgagggtaa
     4741 caccacttac aagaactgct gataaaattc tttttttcat aataaaaaaa ctactccttt
     4801 tcgataagac atcttatatt ttaccaaaaa aaaaagtatt taatattacg caattgttac
     4861 agtt
//
LOCUS       DAUGQX010000071         4721 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUGQX010000071 DAUGQX010000000
VERSION     DAUGQX010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4721
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.071"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1523
                     /locus_tag="VIA51_001665"
     CDS             <1..1523
                     /locus_tag="VIA51_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEQ8683595.1"
                     /translation="TSEVLRKKTHKLFYSEFENQLFETIMFLSMKTLVLDINHFSKEI
                     ENKSEAYEQYIQQIREENGINHFFDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSE
                     IKSCFNISEPLSNVAFSLGDSHSKKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLL
                     KSSNIPSFSLPKSLVKADYCWQLGVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDLH
                     MENVIVSGGDLYLIDVETFFQRKLNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEK
                     NSAPNVSGISGKGGKRKKGKYELINKNRGDMKLVKVDYFQEDGFNIPTLNGKVVEPLD
                     YANEIISGFRECYIFLLSQRSKIKEIVEGFPELKSRVPFRNTSDYGKFLQASTNPKYL
                     FSEKKRKNLFSILYETKHIEHFIVDNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNL
                     GDTTSLFDSITILNDERLKFTCELLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            1525..2058
                     /locus_tag="VIA51_001666"
     CDS             1525..2058
                     /locus_tag="VIA51_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683596.1"
                     /translation="MDKTDFRNISAFVPQDSPIFDGDVMYNILLGRESVTEKQVIEIC
                     KRVSLYEDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRVLVTHRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDY
                     CDLYDSYMNKYQEEEVK"
     gene            2055..2792
                     /locus_tag="VIA51_001667"
     CDS             2055..2792
                     /locus_tag="VIA51_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8683597.1"
                     /translation="MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGNIYCADKEISTFSDKEATNFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVILLKDGK
                     LHMEIDKKDCGESFYDVISQALSDRGE"
     gene            2794..4701
                     /locus_tag="VIA51_001668"
     CDS             2794..4701
                     /locus_tag="VIA51_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8683598.1"
                     /translation="MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIIT
                     EKIGDSGQALVIANGSLIFLIVFLVVFLIYFNNFFVKKRSQELGVLAILGFSKRELTK
                     LLTLENLVILVLSYLVSLLLGPTLYFLAVLAITHLLNLTMEVQWFITVNEIIESLGIL
                     VVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLAT
                     VFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKENKKRLYRPLSNI
                     IYPKFNYRIATKNKLLTVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVES
                     ENGQVNVTTILENDQVSLVDVGLLRLNTIPEVTITDSGQTIPYFDIINYSDYKELMKA
                     QGRTNSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTNNVFSFSTSVTTL
                     VVSDKLYAKLSSRFPEKEMTIRTFNGTSIRSSEAFYNQFSMVPDVISSYSKEHTVKTA
                     NIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYE
                     TGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVL
                     TLRLVTSIIKN"
BASE COUNT         1642 a          635 c          853 g         1591 t
ORIGIN      
        1 aaaccagtga agtgttaagg aaaaagacac ataagttatt ttatagtgag tttgaaaatc
       61 agttatttga aacgatcatg ttcctttcga tgaaaacact agttttagat ataaatcatt
      121 tttccaagga aattgaaaat aagtcagagg catatgagca gtatatacag cagataagag
      181 aagaaaacgg aataaatcat ttttttgaca ggtatccgta tttgctaaaa caaattaata
      241 aagaagtagg actgatagag gaatcatatt ctttattatt tgatagattt ttagaagact
      301 tatctgagat aaagtcgtgc tttaacatta gtgagcccct aagcaatgtt gccttttcac
      361 ttggtgacag tcactctaaa aagcaaacag tcgttaaaat tgcgtttaaa gagaaatctg
      421 tttactacaa gcctaaaagt tatcattcac acagtatctt gttagaactt actagtttat
      481 tgaaatctag taatataccc tcattcagtc ttcctaaaag cttagttaaa gcagattatt
      541 gttggcaact tggtgtagct tatacaagtt ccaataaaga tgaagtagcg aaaatttact
      601 ttaagtatgg tgttttagca gcattttctg aaatattttc tattacggac ttacatatgg
      661 aaaatgtgat tgtttcaggc ggagatttat atttaattga cgttgaaaca ttttttcaaa
      721 gaaagttgaa tgtacaaaat cagaattttg aagggattac tgtagacacc tatcagagaa
      781 tttatgagac atcactttca aacggtttat ttcctgtaca atttgagaaa aacagcgctc
      841 ctaacgtttc tggaataagt ggaaaaggtg gaaaaagaaa aaaaggaaaa tatgaactga
      901 taaataaaaa tcgtggagat atgaagttag taaaagttga ctattttcaa gaagatgggt
      961 tcaatattcc cacattaaat gggaaagtgg tagagcctct tgactatgct aatgagatca
     1021 tttcaggatt tagagagtgc tacatatttc ttctatcaca acgttcaaag attaaagaaa
     1081 tagtagaagg ttttccagaa ttgaaaagca gagtcccatt tcgaaatact tccgactatg
     1141 gaaaattttt gcaagcttct acgaatccaa aatatctttt ctcagaaaaa aagaggaaga
     1201 atttattttc gatactatat gagacaaaac atattgaaca ttttattgtt gataatgaaa
     1261 ttaaagattt gatgaatggt gatattcctt acttttcaat ggataccaga ggaaacgtct
     1321 ataattctgt agggacatta attggaaatc taggagatac aacctcgtta tttgatagta
     1381 taactatttt gaacgatgaa agattgaagt tcacttgtga attgcttgaa atagtcttga
     1441 aaaaaccgat taagcattgg gagagggaaa agggcaaatc ttatcagttt ttatcaatct
     1501 cctcagaaca ttaccttctc taaaattgat aaaactgatt ttaggaatat atcggctttt
     1561 gtacctcaag attctccaat atttgatggg gatgtgatgt ataacatttt gctaggaaga
     1621 gaatctgtta cagaaaaaca agttattgaa atctgtaaaa gggtatcact atatgaggat
     1681 atcaggagta tgccaatgaa gtttcatacc ccactttttc gagacaatcc atcactatct
     1741 ggggggcaaa aacaacgaat ttctctagca agagagttag taactacccc tagaatctta
     1801 gttcttgatg aacctacatc agctttagat gtaaaaactg aaagaataat ccaaaaaaat
     1861 gttgaggctt tacattgtac gagggttttg gttacccata gacttaatac agttgaaaaa
     1921 gctgataaga ttttaataat ggataatggc aaaattattg actatggaaa ccatcattat
     1981 ttgtacaaaa ataataagga ttattgtgac ttatatgact cgtatatgaa taaatatcag
     2041 gaggaagagg taaaatgaaa caattagtat taaaagatgt ttgcaaaaaa tatcccaatc
     2101 aactgaatta tgctctagac catatcaatt tgattgtgga aaaaggagaa tttgtagctg
     2161 tcatggggcg tagcggtagt gggaaaacga cgcttttaaa tgttacttca attattgata
     2221 aaattgatag tgggaatatt tattgtgcgg ataaagagat tagcacattc tctgataagg
     2281 aggcaactaa ttttagaaaa aatgatattg gttttgtttt tcaagattat atgctgttag
     2341 atagtctaac cattagggag aatatttctg ttgctttgtc tctaaaaaat attgattctt
     2401 caaagattga tgatttgata aatagctatg caaaaagatt taatttatat gaacagttga
     2461 agaaatatcc gtatcaactt tctggaggtc aaagacagag ggtcagtatt atcagagcaa
     2521 tcattaaaga accagagatt atttttgctg acgaaccaac tggagcactt gacttgaaat
     2581 cttctgagga aacaatgatg attttgagtg aaatcaataa aacagaaaag gtaactattt
     2641 taatggttac tcatgacgtt ttatcagctt cttatgctga cagagttata ctcctcaaag
     2701 atgggaaact tcacatggag attgataaaa aagattgtgg agagtcgttt tacgatgtaa
     2761 ttagtcaagc tttatccgat agaggagagt aatatgattt ggtcaattac aaaatctaac
     2821 attaaaaaaa atttttcgtt atatcgtatc tattttctag ctacgattgg tttattaagt
     2881 atttttatag cttttctaaa ttttatctca gataaaatca ttacagaaaa aattggggat
     2941 agtggtcaag ctctagttat cgctaatggg tcattgattt ttttgattgt atttttggtg
     3001 gtattcttaa tttacttcaa taatttcttt gtaaaaaaac gtagtcaaga gcttggagtc
     3061 ttagcaatac tagggttttc aaaaagagaa ttaacaaaat tactaacttt agaaaatctt
     3121 gttattctag ttctgagtta cttggtaagt ttattgctgg gaccgacttt atatttttta
     3181 gctgtactgg caattactca tctattgaat ttaacaatgg aagttcagtg gtttattaca
     3241 gttaatgaga ttatagagtc tttaggaata ttagtcgtag tttttctgat taatgtcatc
     3301 acaaatggac ttatcattag taaacagtct ttgattgaat ttgttaattt ctcaagaaag
     3361 gctgagaaaa aaattaagat aagaaaagtc agagctatta ttgctatcac tgcattgcta
     3421 ttgtcatata ttttatgttt ggcgacagtg ttttcatcca cacgaaatat gctattaagc
     3481 atagggatgg taccggtttc tctattgata attgtcttag ttgttttagg aacagtgttc
     3541 accatcagat atggattggc ttttgtagtt tcgttgttaa aagaaaataa aaaaaggtta
     3601 taccgtcctc tgtctaatat catctatccc aaatttaact atcgtattgc aacaaaaaat
     3661 aaattattaa cagtcttggg aggtctttta acagtaaccg tttcagttgc cggaatgatg
     3721 gtaatgctct atgcttattc tcttaatggg atagagaggt tgactccatc tgccatagaa
     3781 tataatgttg aatcagaaaa cggtcaagtc aatgttacaa ctattttaga gaacgaccaa
     3841 gtgagcttgg ttgatgttgg cctgttgcga ttgaatacta tcccagaggt gactatcaca
     3901 gactctgggc aaacaatacc ttattttgat ataattaact acagtgacta caaagagtta
     3961 atgaaagctc aaggcagaac aaattctatt gaaggtagta agtcactccc attgttaata
     4021 aattattatc caacagaaat tagccttgga aaaaccttta acttaggaaa tgcatatgat
     4081 gttactgtaa aacaagtatc aacgaataat gtttttagtt tttctacaag tgtcacgacc
     4141 ctggttgttt ctgataaatt atatgctaaa cttagttctc gttttccaga gaaagaaatg
     4201 acaattagga cttttaatgg aacttcgatt aggtcaagtg aagcatttta caatcagttt
     4261 agtatggttc ctgatgttat cagtagttat agtaaggaac acacagtaaa gactgctaat
     4321 attgcgactt atatctttat aactttccta tccatactct ttattatttg tacaggtagt
     4381 attctgtact ttacaagcct catcgaaatc atggaaaata aagaagaata tggctatcta
     4441 agtaagctag gttatagtaa aaaaatgatt catcggattc ttcgatatga aacaggtata
     4501 cttttcctta ttcctgtatt cattgggatt gtaaatggtg gtatgttgct tatttactat
     4561 aaatatttat tcatggatac attggtagca ggcaatatca taatgttatc tttattgctt
     4621 tgtctgcttt tcttcttgat aatatatggc acattttatg tattgacatt gcggttagtg
     4681 acatccataa tcaaaaatta attttaaaaa tcttttaact t
//
LOCUS       DAUGQX010000072         4442 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUGQX010000072 DAUGQX010000000
VERSION     DAUGQX010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4442
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.072"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            34..2307
                     /locus_tag="VIA51_001669"
     CDS             34..2307
                     /locus_tag="VIA51_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEQ8683599.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNTEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEELSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADG
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(2425..3504)
                     /locus_tag="VIA51_001670"
     CDS             complement(2425..3504)
                     /locus_tag="VIA51_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEQ8683600.1"
                     /translation="MKNISRKCFMTSVVCIILGGILLGTGYATGGLQDIKHQTAPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKLIDPIVTTVTGKTLSLSQTP
                     KDVVITGGIEILGFTLNNSRQEKNYRSITITVPEKTSLNEVKASNVPHTTLSNLTVQD
                     MQFDGNLTLLHTKVKKATITGMLEATKSQLTNLELKADYSFSNLTDSSVENGTISLGN
                     GQLTTKDTTLKAVNIQSLHPGGIEAERTTLENVTFTVSKSKEEEENDYYDNDAIFTAH
                     ALTLKGTNTITGGDIDVDITLTKAKAIAYRARTENGKVSLGSQLTPAKIGKESTSDVI
                     SYVAENKAATGNLTVNLNKGDITIK"
     gene            complement(3501..4088)
                     /locus_tag="VIA51_001671"
     CDS             complement(3501..4088)
                     /locus_tag="VIA51_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEQ8683601.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATAFLRFSGRAFVAFIKWISNKKGAQA"
     gene            complement(4075..4401)
                     /locus_tag="VIA51_001672"
     CDS             complement(4075..4401)
                     /locus_tag="VIA51_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEQ8683602.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
BASE COUNT         1321 a          846 c          908 g         1367 t
ORIGIN      
        1 tttttgaaca gtatgtccat tttaggagaa aatatgttag aagaattgaa aacacttatt
       61 aaaaatccaa aattaatgat tacaatgatt ggtgtggccc tagtgcctgc cttatataat
      121 ttatcctttc taggctcaat gtgggatcct tatggtcggg tcaatgacct tcccattgct
      181 gttgttaatc atgataagcc tgcaaagaga gctgataagt cattgacaat tgggaatgat
      241 atggtggaca agatgtctaa aagtaaagat ttagagtatc attttgtctc agctaagcaa
      301 gctcaagagg gacttaaaga aggtgattat tatatggtta ttactttacc cgaagatctt
      361 tctcaacggg cagcaacctt attaaatacc gaaccccaaa aattaactat ccgttaccaa
      421 acgagtaaag gacatggaat ggtcgctgct aagatggggg aaacagcgat ggctaagctg
      481 aaagagtctg tttcgcaaaa cattacgaag acttatacct cagcagtttt tagcagtatg
      541 acagacctcc aatcaggatt aaaagaagcc tcagctggaa gtcaagcact tgcttcagga
      601 gcgaagactg ctcaggcggg gagtcaaaca ctttcgacga acttagcagc cttaacgggt
      661 gctagccaac agtttcaaca aggtactggt cgattgacat caggtttgac tacctataca
      721 gatggtgtca accaagtcaa gaatgggtta ggaacattat caacggacat ccccaattat
      781 ctgaatgggg tttctaggtt atcccaggga gcttctcagc ttaatcaggg tctttcacag
      841 ttgacacaag caacaacact ttctgacgag aaagctaagg gaattcaatc cttaattgta
      901 ggactaccag tcctaaatca aggcattcag caactaaata cagagctatc aacattgcaa
      961 ccccctaacc ttaatgctga tgagttaggt aatagcttag gagctatcgc tcaagctgcc
     1021 aaacaagtca ttgctgaaga gactgccgct cagaatgaag aattatcggc tctccaagct
     1081 actagcgttt accaatcatt aactgctgaa caacaaggag agttagctgc ggccctcagt
     1141 caatctgata aaagtcagac cgtatctgca gcccaaacta ttttaagttc tgttcaaact
     1201 ttgtcaacaa gtttacagtc tctctctcaa gaagatcagt caaaacagtt ggagcaactt
     1261 aaggaagctg ttgcacagat tgctaatcaa tccaatcaag ctttgccggg agcaagttct
     1321 gctttaactg aattatcaac gggattagca aaggtaaatg gtagcttaaa tcaacaagtt
     1381 ctaccaggaa gtaatcaatt gacaacagga ttagcacaat taaacaggta taatactgcc
     1441 attggttctg gggtaataaa actctcagaa ggtgccaatg ccttgtcatc caagtccgga
     1501 gaattactag atggtagcca tcaattatca gaaggtgcta ctaaactagc tgatggtagt
     1561 tctcaattga gtcagggtgg tcatcaatta acgagcggat tgactgaatt atcaacagga
     1621 ttgtcaacct taaatggttc cttagccaaa gcctctcagc agttatcgct tgtttctgtg
     1681 actgataaaa atgctaaagc tgtcgcaaaa cctcttgtgt taaatgagaa agacaaagat
     1741 ggtgttaaga cgaatgggat cgggatggca ccttatatga ttgctgtttc tctaatggtt
     1801 gtggcccttt caaccaacgt catttttgct aattctttat ctggtcgtcc ggtcaaagat
     1861 aaatgggatt gggctaaaca aaaatttgtt attaatggtt ttatttcgac tatgggatcc
     1921 attgttctct acttagctat tcaattatta gggtttgaag cccgttatgg tatggaaacc
     1981 ttaggattta ttatgctaag tggttggacg tttatggctc ttgtcacagc tttggtcggt
     2041 tgggatgatc gatatggctc ttttgcttct ttggtcatgt tattgcttca ggttggctct
     2101 tcaggtggct cttaccccat tgagttaagt ggagcattct tccaaaagtt acatcctttc
     2161 ttaccaatga cttatgtggt atctggttta cgacaaacca tttcattatc aggtcatatt
     2221 ggagtagaag tgaaagtctt aactggtttc ttactggcat ttatggtatt agcactactc
     2281 atttatcgtc ccaagaaaac agtctaaata aaataacctc aaaaaaaaaa cagcatctaa
     2341 ggcagttaca ctagatgctg ttttttgtct tattttgaca ataacttgac aatttctgtc
     2401 aagtttttta ttgtcttgtt aagattattt gatagtaatg tctcccttat tgagattaac
     2461 cgttaaattt ccagtagctg ctttattctc agccacataa gaaataacat ctgaagttga
     2521 ttccttacca atcttagctg gtgtcagctg tgagccaagg gagactttac cattttcggt
     2581 ccttgctctg taggcgatgg cctttgcttt tgtcaaggtt atgtcaacat caatatcacc
     2641 accagtaata gtattagtcc ctttaagggt aagggcatga gcggtgaaga tagcatcatt
     2701 gtcatagtag tcgttctcct cttcttcttt gcttttagaa acagtgaagg tcacattttc
     2761 aagggttgtt ctctcggctt ctataccacc agggtgtaat gattgaatat tgacagcttt
     2821 tagagtggta tctttagtag ttagttgtcc atttcctaag ctgatggtcc cattttccac
     2881 actagaatca gtcaggtttg aaaaagaata gtcagctttt aactcgagat ttgttaactg
     2941 acttttagtg gcttccaaca taccagtgat agtagctttc ttgactttgg tatgtaaaag
     3001 agtaagattg ccatcgaatt gcatatcttg gacagttaga tttgacaaag tggtatgtgg
     3061 gacattactt gccttaactt cattgaggct agttttttca ggaacagtaa tggtaataga
     3121 acggtagttc ttctcttgac gactattatt gagagtaaaa cctaaaattt caattccacc
     3181 agtgatgaca acgtctttag gtgtttgcga aagagatagg gtcttacctg ttactgttgt
     3241 gacgatagga tcaataagtt taggatgtgt gtaataggtc actgttggtc tttgaacggg
     3301 tcctgtctct actgtaatag ttgaggcaga actgtcaata tcaagagcag ttatttggtc
     3361 aaatgttttg atgacctttt tgggagctgt ttggtgttta atgtcctgaa gtcctccagt
     3421 tgcatagcca gtccctagaa gaatgcctcc tagaataata cataccacac tggtcataaa
     3481 gcatttgcgt gagatatttt tcatgcttga gctcctttct tattactgat ccacttaata
     3541 aaggcaacaa aagcccgtcc tgaaaaacga aggaatgctg tggcaataat ccaaataaga
     3601 agaccaccac caaaacacaa caaggcgctg ccgatgccca tagcttgtgc aggaatagat
     3661 gagccaatca aggtcaagct ttcaaacagg gtcactcctg cgacaagaat acctgcaagc
     3721 ccaaaaatgt aggcggcaaa gatagctgtg agcccgagca ttaggcaggc aataataaag
     3781 agaatcaacg ccagcaatac gggtaaagca atcggagcag caaagaggga caaaatggtt
     3841 aatccaataa ttgttgcccg atttttggga gttttctcgg gagttgccaa gtgttttcct
     3901 agaacatttg aaatgatttc actggcagct tccttaggat ttcctaaatc gtcgataacc
     3961 tggctttctt tgtcaggacc agcttcatca aaatattcaa tataatattc catcgcttca
     4021 tggtagtctt ctctaggtag tttgcgcaag tatttatcta gttctgctag atactcagtc
     4081 cttgtcatgt cttaagctcc cttcgataat cccgtctaag gcaaatttat agctctgcca
     4141 ttcttttttt agaaaaatca gctgtgctct ccccgaagaa gtgacagcat aatatttacg
     4201 ctttcgtccc tgatgttctt gactataagt tgtcaaaaaa cctgctttct ccaatttttt
     4261 aagaatagga tagagagtgg attctttgat attagccact agtttaatgg tttgactaat
     4321 atcgtaaccg taagaatcat ttttttcgac aatggctaaa atcagaaatt caatcaaggt
     4381 agccgatact ggaaaataca ttttaggctc ctttcatata taaaaatttt atatataatt
     4441 at
//
LOCUS       DAUGQX010000073         4405 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUGQX010000073 DAUGQX010000000
VERSION     DAUGQX010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4405
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.073"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            11..811
                     /locus_tag="VIA51_001673"
     CDS             11..811
                     /locus_tag="VIA51_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEQ8683603.1"
                     /translation="MGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQS
                     EARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLS
                     DVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFDGTLHFIPNRSITVVS
                     NKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQ
                     FTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS"
     gene            complement(876..1436)
                     /locus_tag="VIA51_001674"
     CDS             complement(876..1436)
                     /locus_tag="VIA51_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEQ8683604.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(1450..1920)
                     /locus_tag="VIA51_001675"
     CDS             complement(1450..1920)
                     /locus_tag="VIA51_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8683605.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            complement(1910..2674)
                     /locus_tag="VIA51_001676"
     CDS             complement(1910..2674)
                     /locus_tag="VIA51_001676"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEQ8683606.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            complement(2664..3413)
                     /gene="truA"
                     /locus_tag="VIA51_001677"
     CDS             complement(2664..3413)
                     /gene="truA"
                     /locus_tag="VIA51_001677"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEQ8683607.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            complement(3598..4149)
                     /locus_tag="VIA51_001678"
     CDS             complement(3598..4149)
                     /locus_tag="VIA51_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ8683608.1"
                     /translation="MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRH
                     YYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQ
                     KRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
                     RFKGRRALLRKISPYFKEFAQQL"
     gene            complement(4175..4248)
                     /locus_tag="VIA51_001679"
     tRNA            complement(4175..4248)
                     /locus_tag="VIA51_001679"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4212..4214),aa:Arg,seq:acg)
     gene            complement(4328..4401)
                     /locus_tag="VIA51_001680"
     tRNA            complement(4328..4401)
                     /locus_tag="VIA51_001680"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4365..4367),aa:Asn,seq:gtt)
BASE COUNT         1394 a          978 c          649 g         1384 t
ORIGIN      
        1 tatcgaaaat attggcttaa cgatttttaa aaagctagtg tctctcatta ttctattact
       61 cttttttgct attttaaaac gtgttactaa ctatcttttt gaaaaaacca ttaacaaatc
      121 gtttgcttat tcaagacaaa gtgaagctcg caaaaaaaca ctctctaagc tcactcacaa
      181 cattttaaat tacttattat attttcttct catttattgg atacttagct tatttggcat
      241 acctgtctct agtcttctag caggagctgg aattgctgga gtagcaatcg ggttaggtgc
      301 acaaggattt ttatctgacg ttgtcaatgg cttttttatc ttatttgaga atcaatttga
      361 agtaggagat aacgttacta tctctgacat agaaggcagt gtctttggtg ttggaattag
      421 aactactcaa attcgtggat tcgatggaac actacatttc atcccaaacc gtagcatcac
      481 cgttgtcagc aacaaatctc gtggtaatat gcgtgcctta attgaaattc ctctttattc
      541 cactgttaat ttgagccaag tcactcgaat cattgatgaa gtgaatcaaa aggaattgcc
      601 aaaccatcct caaatcgttg gcaaaccaaa tattttaggg cctcaaaata actctaatgg
      661 acagttcact tttagaattg ctattttcac agaaaatgga gaacaattta agatttacca
      721 tactttttat agactttatc aagaagcttt actcaaagaa ggcattcaat taccgactgc
      781 aatcagctat tctatcacct caaaatctta atataatctt aaaaaatcct tttttctaga
      841 aaaaacacca attgttttat tccagaaaaa agggtttagg atttacggat aatatccata
      901 ttgtaatcag ccctagctcc accaattaat tttggtcgac tagccaaagc tgtcacatga
      961 gcacctccta gctctcgttg acaaggaatc agagggatct gaacacgctt aatatgcatt
     1021 cctatagcag tatcacctat atcaagtcca gcgtgtgcaa taacttcttc tacttcgaca
     1081 gggtctgaca taagttgaaa agcagccatc tgagcactgc caccagcatg aagattcgga
     1141 accacattga caatctctaa ctgcttagat tctgccacat gcctctctac taccaaggca
     1201 cgattgacgt gttcacaacc ttgtacagcc aaatgaacac cacgcttatt taattcatct
     1261 aacacaactt caacaactat ttgacctact tctagactag attgttttcc aattctacta
     1321 cccaaaattt cgctagatga aagacctaga acaaaaagat tacctggttg aatagcagag
     1381 cgttctacaa catcaatgac gatttccctt gtttgtttct ctaaattatt caacaacttc
     1441 tcactctcct tatctctttt tttgccttaa tatggcctta aagataataa aaccaacaaa
     1501 aagccctaat gtattttgca tgacgtttcc ccaaataccg gctaaagatc ccgaaaggcc
     1561 ataaccaagc ataagagagc ctaaaaagta ccaaaaaatc atgataaaag aacctatcac
     1621 aacaccaagc caacgcttgc gccctctcca tcccgcaaaa tacccttgga cactgtgagc
     1681 aatcaaacta tgaaacatcc actgagggta tcctgccact aaatcgatta aaaaacctga
     1741 taaccctccc acaatagctc cttgagctga tccaaaggaa aagctgacag cataaattcc
     1801 tgcatccaac agcgttaaaa aacctgttgg agtaggtagc atgacaaatc ttcctaaaac
     1861 aacaaccaat gctgtcaata tccctgttaa actcatttgt cgtatcttac tattttgcat
     1921 aactttgttt tactccgtat ctatcagatt gtaaaatagc ttggtagact aactcttttg
     1981 agtttttcac agcttctagt ggcgtttttt tctttactaa ctgactagcg atactagatg
     2041 caaaagtaca gcctgcgcca atattatttt tctcaagtac aggacattcc aaggtaacaa
     2101 tctctttacc atcataaaaa agatcaatag cttttttctg actaaatcga ttaccaccct
     2161 tgataaccac ctgttttgcc ccaagttgat aaaaatattt agcagcttct tgcatatctt
     2221 ttaaagaaac aatctctttt tgagataata gctgagcctc taccaaattt ggagtaacaa
     2281 cagtcacata aggcaataat tgtaaaatct cctgtcttag aggaactatt ttaacatcat
     2341 ctatttcttt acatgctaga acaggatcta aaaccactgg gattcccaga tgccccttta
     2401 taaaatccaa aactatttca cacatttccg cattaggtaa caaaccaatt ttaatagcag
     2461 aaattggagc gttcgtaaag ctattcaact gatcacggaa aatttcttta gctaccggaa
     2521 atagactaaa gccctcttca gatctagtag ttaaacaagt taccgctaca aaggcctgta
     2581 ggtcatacct tatgtaagtc gctaaatcag catagagacc acctccactt aaaatatcgt
     2641 tcccagatat agtcacgata taatcagttt tcataacaaa tctccttcaa gtaaagccca
     2701 tttccagata tcgttggtcc agctagctga cgatttttgg agctcaaaat cactttaact
     2761 tgttcaactg gcatttgacc attaccaatt ttcagcaaag ttcccaccat attcctcacc
     2821 tgcttataga gaaaaccatt tcctgaaaaa gtaaacacca aaaaatcagt tttttcatcc
     2881 cgagataccg ttgctttggt aatcgttcgc accttatttt gtaccgaagt tcctgctgct
     2941 gtaaaaccag taaaatcgtg tgtacctacc agaccgttaa tagcttcttg cataagttta
     3001 atattaagag tataagggta atgagtggta tagtgtcgca tcatcggatt tttaggtcga
     3061 ccattatcaa ctaaaaattc ataagttttt aaatgcttct gataacgaca atgaaaatca
     3121 tcagccactt tttctatatt aacaacatca atatcttcag gagtctgtgt atcaagagca
     3181 aatcgcaatt tttcaacttc ttgttcttga ggcaaatcaa aatggatcac ctgtccataa
     3241 gcatgtactc ctgcatccgt acgtcctgca ccatgaatta taatttttgt accgttattt
     3301 aatttataga gtgttttttc aatctcttct tgaaccgtac gtaaatgtct ttgtctttga
     3361 aaacccgaaa aaagagtccc atcataggaa atcgttgctt tgtatcttac catgttacta
     3421 ttttaacatt tcttaaacgt aagagaaact atttttaatc aaactgtacc caaacaaatg
     3481 aaagacgtat tgaagcttac tctaagctac tagcgattta aaagctataa gaaagctatt
     3541 tcctccaaac tctctccttt tttcatagat ttacccccaa ttccttatag gtcttgctta
     3601 caactgctgt gcaaattcct taaaataggg actgatcttc ctaagtagag cacgtcttcc
     3661 cttgaaacgt tcgcccctga taagtgcttg aaactgcata cgctcttgcg aatttaattg
     3721 gttctctaag ctagctatta cctcttgata agccacatag tcgtctagcc ataaccctct
     3781 cgatggaatg gcatgtgcaa cctcccctat ctcttcatat gctaacttat ggaactgacg
     3841 cttttgactt tcttgacggc gtaataaatc tttcaaataa gatgaaaatt ttgttttaaa
     3901 atagcgatat aaacgctctt cttcctcaat taactctggg tacctttcta gtaactgtaa
     3961 taagataata tgtccttctt gtaaccagtc atctctatcc cacaattgaa tataatagtg
     4021 tcgctttaat ttcaaaataa tgggcttaac tttttcaaac gctgctcttg tctctatcga
     4081 cattttgagt ctccttttct ttttaactat ccctagtata aagagaacca caaaaaaaca
     4141 acaggacatt aatgtcctgt tgtttttttc attatgcacc ctagaggagt cgaacctcta
     4201 accgcctgat tcgtagtcag gtactctatc cagttgagct aagggtgcca acgcatatct
     4261 tgcctctatc ttaccacact cttctctaaa atgcaaaaaa agataggacg cttcctacct
     4321 ctctctactc cgccagtagg actcgaacct acgacatcat gattaacagt catgcgctac
     4381 taccaactga gctatggcgg ataaa
//
LOCUS       DAUGQX010000074         4361 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUGQX010000074 DAUGQX010000000
VERSION     DAUGQX010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4361
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.074"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..1136)
                     /locus_tag="VIA51_001681"
     CDS             complement(<1..1136)
                     /locus_tag="VIA51_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEQ8683609.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYYCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NTGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSY"
     gene            1226..2092
                     /locus_tag="VIA51_001682"
     CDS             1226..2092
                     /locus_tag="VIA51_001682"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEQ8683610.1"
                     /translation="MKRIVVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQNPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            2070..2627
                     /locus_tag="VIA51_001683"
     CDS             2070..2627
                     /locus_tag="VIA51_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8683611.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRVPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            2761..4305
                     /locus_tag="VIA51_001684"
     CDS             2761..4305
                     /locus_tag="VIA51_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8683612.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
BASE COUNT         1416 a          659 c          852 g         1434 t
ORIGIN      
        1 ctataagagt ctgatgtcgt gtaatcaatc actaaatgag taggggttag ttgatagtga
       61 atatcagggc aattttgttt taaaaagaga gccaattgac gttcccgctg ttttagataa
      121 cgcttaataa agcgaagatt tttttgaaac atcccatttt ctaaataaag agctaatgct
      181 ttttgcatta gtaagttcgt gtctaaatca atcaatgatt tttgggttaa aaaatgaggt
      241 tttaaacctg acggtaaaac tagagctccg atacggagtg caggaaaaac actcattgaa
      301 aaagatttta ggtagatgat tcggtgatga gtgtcataat aatgaattgg tggctcttta
      361 agtttcacaa aatctcctaa ataatcatct tctaaaatat aaacctggta tcgttgtgct
      421 agacgaacaa tagcttcctt ttccttagtg ctataagaaa gtcccagagg atgtgaaaat
      481 cgtgaaatcg tgtaaaaaaa tttaatatcg ccagtttgaa ataaagattc taagagttct
      541 aaatcaaggc cattaaagtg tctagagata gtttgatagg gtaatcctaa ctgagcaaca
      601 atagcttcca tccgatgata agtaggcttt tcaaggagaa ttgttttgcc cgtattagga
      661 aaaggcattt gtgataaaat ataaagcgct tgttgcgtcc cagaggtgat taatagttgg
      721 tctttgttac tgtaaacact attttcagct aagtaaagaa gcaaagcttc ccttagttct
      781 tctagtcctt cggttttgtg ataataatga aagaggtatt tgtctttagc acttaaggcc
      841 tcatttaagc agagtcggaa atcttcataa gccatattat tataatcttc aagacttaga
      901 ttaagaacat tatcgggcat gcttacgtta cccaaaacat aataaccact tttaggaaca
      961 gcataaatta agtgacgata ttttaattct aaaagagccc gctgaacagt atctttgcta
     1021 caataataaa ccttacttag taccctaatt gaaggtagct tgtccccttt ttttagtcgc
     1081 tgtttctgga tatcttgttc gatattggaa atgattgttt gatattttgt tgtcataaat
     1141 tgtccccata cagttaagtg ttataactat tgtatcttat gcctcttttt cttacaatag
     1201 ttattataga aaagaggtaa tagctatgaa acggattgtt gtggcaaatg atctggttgg
     1261 tgttggtaag gtagccttgt ctgctagtat tcctttaatg gcttcttgtt tgttagagca
     1321 agttttatta ccaacttgcc ttttatcaag ccatactggc ggaggacaga accctgtgaa
     1381 gcatactaca tcaagtatat tagacgtttt tttaacagat tgggacaaca aaagaattaa
     1441 gtttgacggc atttttatag gttattttac gacaacaaga gatgggcaaa agctgctaga
     1501 atggctttca agaaagcaac ttcccttaat tttagatcca attatggcag ataatggaaa
     1561 actttatcaa ggcttcagtc aaaaacatat agagattatg ataaaactta ctcaaaaagc
     1621 tgagcttgtt ttacctaata ttagtgaggc ttgtctatta acacaaacag cttatttagc
     1681 aaaaaattat gatgaagaag atattagaca ggtggctaga aaattagcta agcttggacc
     1741 taaacaggtt gtcattagcg gaatctcttt tgaggagggc agcattggtt ttgcttacta
     1801 tcagtcagat tcagatcaat taacattcca ttttgggaag caattccctt accatttcta
     1861 tggtacagga gatatagcat cagctattat aacagcagga ttctattatc agctaccact
     1921 aacacaaatt ctagatcttg ttgtttcatt tcttgaaaaa gtattgcaaa atacccttac
     1981 attaaaaaga gatttaatct taggtgttgc ttatgaatct catttaaatt acttaactaa
     2041 atcgtttaaa aagttgttgg aggaaaaaaa tgtcatctca aaaattagct aattatattg
     2101 aattgagtat gtatgccgct ttaattttta tttcagtaca agtgttgcgt gtccctgtcg
     2161 gtatgcagtt tattcatctt ggcaatgcat tagttgttat tgcagtctta atctatggta
     2221 gtaaaaaagg agctctagtt gctagtcttg gtttagggat ctttgatgtt ttgaacggct
     2281 atgcttcagt cgtttggata actatcttag aatccttggc tatttgttta attttgcatt
     2341 tggtatatga aagagctatg caatctagta aaaaaccaaa agccattata acaataacag
     2401 ttattgctgc attgtcaaaa ttaactatta accttataaa atacttactg ttagcttata
     2461 taggtactca gctaccactt tcggtatctt tttgggtagc tcttggaaaa attggtggta
     2521 gtttcggaac atcttttgtg actttagttg ctgttcctct tttgtatcct gttatcaaaa
     2581 acttaaaaga aaaggttaca atcggacaag caaaaagagg tttttgatac aagtacctta
     2641 tcgataaaaa agcaaggtac acttttagtc aaatattgac aaaaggttac aattttgcca
     2701 taatgaaata actataaagc cgttttgacg gcttttttga tgacagttaa ggaagaaacg
     2761 atgagtattt tagaagttaa gcagttgagt cacggttttg gggatcgggc tatttttgaa
     2821 aatgtgtcat ttcgcctctt aaaaggcgaa catattggac tagttggggc aaatggtgaa
     2881 ggaaaatcaa cctttatgag tatagtcaca ggacatttac agcctgacga aggaaaagta
     2941 gagtggtcga agtatgtcac tgcaggttac ctggatcaac atacagtgtt ggaatcagga
     3001 caaaccgttc gtgatgtctt gcgaactgct tttgatgagt tatttaagac cgagaatcgt
     3061 attaatgaga tttacgcgtc aatggcagat gataaagctg atattgctgt tttgatggaa
     3121 gaagtaggtg agcttcaaga tcgtttagaa agtcgtgatt tctatacttt ggatgctaag
     3181 attgatgaag tagcgcgtgc gcttggtgtt atggattttg gaatggagtc agatgttaca
     3241 tccttatcag gtgggcaacg aacaaaggtt ttattagcca aattactatt agaaaaacct
     3301 gatattctgc tattagatga accaactaac catttggatg ctgagcatat tgaatggtta
     3361 aaacgctatt tacaacatta tgaaaatgct tttgtgttga tttcgcatga tatttctttc
     3421 ttaaatgatg tgattaatat tgtttatcat gttgaaaatc aaagtttagt tcgctatact
     3481 ggggattatt accaatttca agctgtttat gagatgaaac aatctcaact tgaagcagcc
     3541 tatgaacgtc aacaaaaaga gattgctaac ttgcaggatt ttgtcaaccg aaataaggct
     3601 cgggtagcga cacgtaacat ggcaatgtct cgccaaaaaa aacttgataa gatggatata
     3661 attgaacttc aagctgagaa accaaaacca aattttgaat ttaagcaagc tagaactccc
     3721 agtcgattca tttttcaaac aaaaaatctt gtgattggtt atgattaccc attgaccaaa
     3781 gaacccttaa atataacgtt tgaaagaaat caaaaaattg ctattgttgg ggccaacggt
     3841 attggaaaat ctactttgct aaaaagttta ttaggtgtta ttgagccttt agaaggtcat
     3901 attgtcacag gggatttttt agaagttggc tactttgaac aagaagtgac aggtgttaac
     3961 cgacaaactc cgctagaagt agtttgggat gcttttcctg ccttaaatca ggcagaagtt
     4021 cgagcggcac tagctcgttg cggactaaca tcaaaacata tcgaaagtca aattcaagta
     4081 ctttcgggtg gtgaacaagc aaaagttcgt ttttgtttgt tgatgaatcg tgaaaataac
     4141 gtgcttattt tagacgaacc aacaaatcat cttgatattg atgctaaaaa tgagctcaaa
     4201 cgtgctttaa aagcatataa gggttctatt ttaatggttt gtcatgaacc tgatttctac
     4261 aatgggtggg taaccgatac ttgggatttt agtaagttaa cctaaactat tccttaattt
     4321 tttacacaga aattactaaa atcagtaaag atatagaata a
//
LOCUS       DAUGQX010000075         4299 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUGQX010000075 DAUGQX010000000
VERSION     DAUGQX010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4299
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.075"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            77..619
                     /gene="hpt"
                     /locus_tag="VIA51_001685"
     CDS             77..619
                     /gene="hpt"
                     /locus_tag="VIA51_001685"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEQ8683613.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            641..2620
                     /gene="ftsH"
                     /locus_tag="VIA51_001686"
     CDS             641..2620
                     /gene="ftsH"
                     /locus_tag="VIA51_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEQ8683614.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGNVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            2945..>4299
                     /locus_tag="VIA51_001687"
     CDS             2945..>4299
                     /locus_tag="VIA51_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8683615.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     Y"
BASE COUNT         1414 a          629 c          848 g         1408 t
ORIGIN      
        1 tatttgagaa aagcttgtaa acatgatata atgttggcta aactgtatat tgataaatta
       61 gaaaaagggt gacagcatgc tcgagcaaga tattcaaaaa attctttact ctgaaaatga
      121 tattattcgg aaaactaaaa aattaggaga acaattaaca aaagattatc aagaaaaaaa
      181 tccgcttatg attggtgtat taaaaggatc agttcctttt atggcagaac taatgaaaca
      241 catcgatact catgttgaaa ttgattttat ggtagtatca agttatcatg gcggtacatc
      301 tagcagtggt gaagttaaaa ttttaaaaga tgtagatacc aatattgaag gaagagatat
      361 cataattgtt gaagatatta ttgacaccgg tcgcacctta aaatatttac gagatatgtt
      421 taagtaccgt aaagctaata ctatcaaaat tgcaacactg tttgataaac ctgaaggtcg
      481 tgttgttaaa attgaagcag attatgtttg ttacaatatt ccaaatgaat ttatcgtagg
      541 ctttggttta gattacgcag aaaattatcg caatcttcct tacgtaggtg tattaaaaga
      601 agaagtctat tcaaaataga aaaaggtcaa tgtttactgt atgaaaaata ataaaaataa
      661 tggttttgtt aaaaattctt ttatatatat attgatgatt attgttgtca tcacaggatt
      721 tcaattttat cttaagggaa ccagcacaca aagccaacag attagttatt ccaaattaat
      781 taaacatctt aaggctggag atataaaatc tttaagttat cagcctagcg gtagtattat
      841 tgaagttaaa gggaaatatg agaaacctca aaaagtgaca gttaattcag gactatcatt
      901 tttaggtgga agagcttcaa cacaggtaac agagttctca tctttagtat tacctagtga
      961 taccatcttg aaagaaatga cagcagcagc tgataaaaat ggaacagagc ttacagttaa
     1021 gcaggaaagt tcaagtggta cttggattac cttcttaatg agctttttac ctattgttat
     1081 ttttgctgct ttcatgatga tgatgatgaa tcaaggtggt ggaggagctc gtggtgctat
     1141 gagtttcggc aaaaataagg caaaatctca atcaaaaggt aatgttaaag tgagatttac
     1201 agacgttgct ggtgccgaag aagaaaaaca agaattagta gaagttgttg attttttgaa
     1261 aaatcctaaa aaatataaat cactaggagc acggattcca gcgggagttc ttctagaggg
     1321 gcctccaggt actggtaaaa cattactagc taaagctgta gcaggtgaag ctggagtgcc
     1381 atttttcagt atttcaggtt cggattttgt cgaaatgttt gtcggtgtag gtgctagtcg
     1441 tgttcgttct ttatttgagg atgctaaaaa agctgagcgt gcgatcatct ttatcgatga
     1501 aattgacgct gtaggtcgtc gtcgtggtgc tggcatggga ggcggtaacg atgaacgaga
     1561 acagaccctt aaccaattac tcattgaaat ggatggtttt gagggtaatg agaacattat
     1621 cgttattgct gcaactaacc gtagtgatgt tttagatcca gctttactaa gaccaggtcg
     1681 ttttgatcgt aaggttttag ttggtcgccc tgatgttaaa ggacgtgaag ccattttacg
     1741 tgttcatgct aaaaataaac cacttgcaaa tgacgttaat ttgaaagtag tagcccaaca
     1801 gactccaggt tttgtaggtg ctgatcttga aaatgtttta aatgaagctg cgttggttgc
     1861 tgctcgcaga aataaaatta aaattgatgc tagtgatatt gatgaagctg aagatcgtgt
     1921 tattgctgga ccatcaaaga aagatcgcac tatttcgcaa aaagagcgag aaatggttgc
     1981 ttatcacgaa gctggtcata ctattgttgg tttagtttta tctaatgcgc gtgtagttca
     2041 caaggtaact attgtacctc gtggacgagc aggtggttat atgatcgctc ttccaaaaga
     2101 agatcaaatg cttctttcta aagaagatct gaaagagcaa ttagcaggat tgatgggtgg
     2161 tcgtgttgct gaagaaattg tttttaatgc tcaaacatca ggtgcgtcaa atgactttga
     2221 gcaagctact cagatagcaa gggccatggt tacggaatat ggtatgagtg aaaagcttgg
     2281 accagttcaa tatgaaggta accatgcgat gatgccagga cagatctctc ctgaaaaagc
     2341 ttactctgcc caaacagctc aaatgattga tgatgaggtt cgtgaactct taaatcaagc
     2401 tcgtaatcaa gcagctgata tcatcaatga gaatcgagat actcataaat tgattgctga
     2461 agctcttctc aaatatgaaa ctctagacgc tgcacaaatt aaatcaattt atgaaactgg
     2521 taaaatgcca gttgatttag aaactgatga taatgaagct catgcgttat cttatgacga
     2581 aattaaaaat aaaatgacag aatctgaatc tgcagaatga tataaaaaag ctgaacttat
     2641 agattaagtt cagctttttt atcaacacaa tatccttgta aacgttatga attgtaatag
     2701 gtgcctaatt gctagaaatg agaagatgac atactttttt tctttattac ttaaagtgag
     2761 aaagactttg gtatttaaaa ctagaaaatt gttaaagcca tttgaaaaat ctattagtgt
     2821 tttcttagaa taatagaaga acagaagata gcaaaagttt cagtcaacca ataagatgaa
     2881 atttacaatc attactaact atgatacact tagtagaaaa tcatttacta tagaaggtga
     2941 taacatgact atttttcgta aaaaaaagaa atattccaat aaaacagaaa tgcaaaggca
     3001 cttcaaagtt attgatttag tttttttagg cctaggttca atggttggaa caggtatctt
     3061 tacagttact ggcataggcg ctgctaagta tgcaggtcct gctttaacaa tatcgattat
     3121 catttccgcg attgctattg gaattttagc cttattttat gcagaatttg cgtctcgtat
     3181 gccttctaac ggtggtgctt atagttatgt ttatgcaacc ttgggagagt ttccagcatg
     3241 gcttgttggc tggtatatta ttatggaatt tttaacagct atatctagtg ttgctgttgg
     3301 ctggggaagt tatttaaaag gattacttgc caattataat atagtattac caaacgcttt
     3361 aaatggcacg ttcaatctta agaatggaac ttacatagat attcttcctg ttttagtgat
     3421 gtttttcgtg acagggattg tcctaatgaa ttcgaaatta gccctgagat tcaatagttt
     3481 tttagttatt ttaaaatttt cagcactggc tttatttatc tttgtaggca ttttttttat
     3541 tgatcacaat aattggtctc attttgctcc atatggtgta ggacaaatta ctggaggtaa
     3601 aacaggtatc tttgctggtg cttctgttat gttctttgca tttttaggat ttgaatctat
     3661 ttcaatggca gttgatgaag tgaaagaacc acaaaaaaca atccctaaag gcatcatttt
     3721 atctttgatt attgtaacag cactctatat agttgtcacc actattttaa cgggaattgt
     3781 acactacact aaattaaatg ttccagacgc ggtggctttt gctttaagaa atattagact
     3841 ttattgggca gctgactatg tgtcgatagt tgctattttg actcttatta cggtatgtat
     3901 ttctatgacc tatgcattag ctagaacaat ttacagtatt agtagagatg gtttattacc
     3961 taaatcactt tatactctca ctaaaaaaaa taaagtgcct caaaatgcta ctcttgtcac
     4021 tggactactt gctatgattt gtgcgggaat atttccttta tcgagtctag cagagtttgt
     4081 taatatttgt actttagcat atttaattat tctgtcgggt gcaattatta aactcagaag
     4141 aatagaagga gaaccaaaag caaatgaatt taaaactcct ctagtaccat tcctaccaat
     4201 gttggcaatt atcatttgtc tatcatttat gagccaatat aaagctttta cttggattgc
     4261 ttttgctatt gccacaatta ttggaacatt aatctactt
//
LOCUS       DAUGQX010000076         4195 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUGQX010000076 DAUGQX010000000
VERSION     DAUGQX010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4195
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.076"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            325..588
                     /locus_tag="VIA51_001688"
     CDS             325..588
                     /locus_tag="VIA51_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEQ8683616.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            593..2326
                     /gene="ptsP"
                     /locus_tag="VIA51_001689"
     CDS             593..2326
                     /gene="ptsP"
                     /locus_tag="VIA51_001689"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEQ8683617.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            2511..3938
                     /locus_tag="VIA51_001690"
     CDS             2511..3938
                     /locus_tag="VIA51_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8683618.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVSFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            4033..>4195
                     /locus_tag="VIA51_001691"
     CDS             4033..>4195
                     /locus_tag="VIA51_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deacetylase"
                     /protein_id="HEQ8683619.1"
                     /translation="MKKLNVILVGLLSILMLSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSDLVIKAVK"
BASE COUNT         1314 a          743 c          916 g         1222 t
ORIGIN      
        1 aaagctaaaa agcaagctat aaacttatct gaaacacaac atattgtgtt gaaataaaaa
       61 acagaaacct aaatattgtg tcaatctgga ttcttatggt tagagctcta gcgttttggt
      121 gatagaagtt aagcagtttt aataaagcat taaagtctga aaaataaatt gtgaaaaacg
      181 tgaaaataaa agaaaataat ttcacatttt ttgtcgttta aatatttaat cttgaaaata
      241 aaaaagcatt gtgctataat cggttgttgt aagggttatc atgtgatggc tcaaaaatac
      301 acaacttaaa aggagaacca tactatggct tcaaaagact ttcacattgt tgcagaaaca
      361 ggtattcatg cgcgtccagc gactttgctt gttcaaacag ctagcaaatt tgcttcagac
      421 atcactcttg actacaaagg taaagcagta aatctaaaat caatcatggg tgttatgagt
      481 cttggtgttg gtcaaggtgc agatgttact atctcagctg aaggtgcaga tgctgaagat
      541 gccattgcag caattgaaga aacaatgact aaagagggat tggcataaga ctatgacaga
      601 aatgcttaaa ggaattgcag cctcagacgg cgttgctgtt gctaaagcat atctactagt
      661 tcagccggat ttgtcatttg agactgttac agtcgcagat acaaatgcag aagaagctcg
      721 ccttgatgtt gcactccaag ctgcacaaga cgagctttct gttatccgtg aaaatgcagt
      781 agaaagctta ggtgaagaag cagcagccgt ttttgatgcc catttgatgg ttcttgctga
      841 tccagaaatg atcagccagg ttaaagaaac gattcgcgca aaacaaacga atgcagaaac
      901 aggtcttaaa gaagtgactg acatgttcat caccatcttt gaaggcatgg aagataaccc
      961 atacatgcaa gaacgtgcag cggacatccg cgacgttgca aaacgtgtgt tggctcacct
     1021 tttaggtgta aaacttccaa atccagctac aatcaatgaa gaatcaatcg ttatcgcaca
     1081 cgatttgaca ccttcagata ctgctcaact taacaaacaa tttgtaaaag catttgttac
     1141 aaatatcggt ggtcgtacaa gtcactcagc tatcatggca cgtacacttg agatcgctgc
     1201 ggtacttgga acaaatgata ttacaaaacg tgttaaagat ggtgatgtga ttgccgttaa
     1261 tggtatcact ggtgaagtga ttatcgatcc aagcgaagat caagtacttg cttttaaaga
     1321 agctggtgcg gcttatgcca aacaaaaagc agagtggtct ctccttaaag atgcgcacac
     1381 tgaaacagct gatggcaaac actttgaatt ggctgctaat atcggtacgc ctaaagacgt
     1441 tgaaggtgtt aatgacaatg gtgctgaagc tgttggcctt taccgtactg agttcttgta
     1501 catggattct caagacttcc caactgaaga cgaacaatac gaagcttaca aggcagtgct
     1561 tgaaggcatg aatggcaaac ctgttgtggt tcgtacgatg gatattggtg gcgacaagga
     1621 acttccttac tttgaccttc caaaagaaat gaatccattc cttggtttcc gtgctcttcg
     1681 tatttccatc tctgaaactg gggatgccat gttccgcaca caaatgcgtg cgcttcttcg
     1741 tgcctctgtt cacggacaac ttcgtattat gttcccaatg gttgcgcttc ttaaagaatt
     1801 ccgtgctgca aaagcagtct ttgacgaaga aaaagcaaac ttgcttgcag aaggcgttgc
     1861 ggttgctgat gacatccaag ttggtatcat gattgagatt cctgcagctg ctatgcttgc
     1921 agaccaattt gctaaggaag ttgatttctt ctcaattgga acaaacgacc ttatccaata
     1981 cactatggca gcagaccgta tgaacgaaca agtatcatac ctttaccaac catacaaccc
     2041 atcaatatta cgtttgatca acaatgtgat caaagcagcg cacgctgaag gtaaatgggc
     2101 aggtatgtgt ggtgagatgg caggtgacca acaagctgtt ccacttcttg tcggaatggg
     2161 cttggatgag ttttctatgt cagcaacttc agtacttcgt acgcgtagtt taatgaagaa
     2221 acttgactct gctaagatgg aagaatatgc aaatcgtgcg cttacagaat gttcaacagc
     2281 agaagaagtt cttgaacttt ctaaagaata cgtttctgaa gattaaaggg ttaaagagtt
     2341 ggtttaaacc agctcttttt tgctagctaa aaatacaatt actttttggt gtgaaatcat
     2401 ttgagttatc aaataattat caggattttc agatatttag tatagccaaa tcttgaatta
     2461 tatcggaaaa gtgatagaat aagattacta tcataaaagg agataaaacg ttggcaaaac
     2521 aatataaaaa tttagtgaac ggtgaatgga aactatcaga aaacgagatt accatttacg
     2581 caccagcaac aggtgaagag ttaggatcag ttccagcgat gacgcaggca gaggtagatg
     2641 ctgtttacgc ttcagctaaa aaggctctat cagattggcg cgctttgtct tatgtggaac
     2701 gtgcagctta ccttcataaa gcggctgata ttttagtacg tgatgctgaa aagatcggcg
     2761 cgattctttc aaaagaagta gccaaaggtc acaaggcagc tgtcagtgaa gttattcgta
     2821 ccgctgaaat cattaattat gcagcagaag aagggcttcg tatggaaggt gaagttcttg
     2881 aaggtggtag cttcgaagct gcaagtaaga agaagattgc tattgttcgt cgtgaaccag
     2941 ttggtttagt tcttgccatc tcacctttta attatcccgt taacttggca ggttctaaaa
     3001 ttgctccagc tcttattgca ggaaatgttg ttgctcttaa accaccaaca caaggctcta
     3061 tttctggttt gttactagca gaagcttttg cagaagctgg tattccagca ggtgtcttta
     3121 ataccattac agggcgaggt tctgttatcg gtgattatat cgttgagcac gaagcggtta
     3181 gctttatcaa ctttacaggt tctactccaa ttggggaagg aatcggtaaa ttagcgggta
     3241 tgcgaccaat tatgcttgag cttggcggta aggattctgc tatcgttttg gaagatgcag
     3301 atcttgcttt agcagcgaaa aatattgtag ccggtgcttt tggttactca ggccaacgtt
     3361 gtacagcggt taaacgtgtt cttgtgatgg acaaggtggc ggatcaattg gcggctgaga
     3421 ttaaaacact tgttgaaaaa ctaagtgtcg gaatgcctga agacgatgct gatattacac
     3481 cattaattga tacatcagct gctgattttg ttgaagggtt gattaaagat gcaactgata
     3541 agggagctac tgctttgaca gcctttaatc gtgaaggcaa tcttatttca cccgttctct
     3601 ttgatcatgt gacaactgac atgcgtttgg catgggaaga gccgttcggc ccagtattac
     3661 caattattcg tgtaaccact gtagaagaag ccatcaagat ttctaatgag tctgaatatg
     3721 gtttgcaagc ttctattttt acaactaatt tcccaaaagc ttttggcatt gctgagcaat
     3781 tagaagttgg aactgttcac cttaacaata aaacacaacg tggaacagat aatttcccat
     3841 tcttaggcgc taaaaaatca ggtgcagggg tacaaggagt taaatattct atcgaagcta
     3901 tgacaactgt taaatctgtt gtatttgata tccagtaata aaaaaaataa acaaaaagtt
     3961 aggttaactt aactttttgt ttattttttt aatgtttttt gttacaatag tctatacaga
     4021 tggaggcaac tattgaaaaa attaaatgtt attcttgttg gtttattaag cattctgatg
     4081 ttgagtttag ctattgtgtt tattaatcgt tggaaactaa acgaagatag tcagcgtata
     4141 gttttggctg aaaagaaaaa aaacacgtca gatttagtga tcaaagctgt aaaac
//
LOCUS       DAUGQX010000077         4146 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUGQX010000077 DAUGQX010000000
VERSION     DAUGQX010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4146
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.077"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            458..1966
                     /locus_tag="VIA51_001692"
     CDS             458..1966
                     /locus_tag="VIA51_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8683620.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVKLSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            complement(2315..3664)
                     /locus_tag="VIA51_001693"
     CDS             complement(2315..3664)
                     /locus_tag="VIA51_001693"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEQ8683621.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKDEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
BASE COUNT         1251 a          813 c          720 g         1362 t
ORIGIN      
        1 aactagctct ctcaaaaaag attaaaaata aaggcattct aaagaatcat ttaagaaaac
       61 tttaaggtta ctatcgtaga atgaaaacat cctaaaaagc ggtttaccta aaccgttggg
      121 agaataggtt ttccccttgt tttccctttt cataaatctc ctgggcacct atcttcttag
      181 gtgccctccc ttgtttaaac ctgaccagtt aaccggctgg ttaggttttt aaatttaaaa
      241 agtcaacagc aaaaatatga tttcacccgc gtgttcttag ctctctcaat tatgggctaa
      301 aaacacgcat caatcaatct attgatgaag tttgctgctt tttgatgatc tttattgtga
      361 ctatactggt aatcctattg attttagttg acttttacgg tagattcgct acaatatata
      421 ggattataca atttaattta aggagagaaa aattacattg ttagattatt atttggaatc
      481 cgatattatt gaccagaaaa tcctactggc tattttgttg acagaaaaag aactgacgat
      541 ggcagcagct tgttctcaaa caactttgac tgctttaaaa ataaagcagt atcttcgaca
      601 atttaacgcc ttatttaaag ggtacttacg tattgagctt attaaatctc gtatttattg
      661 tgaggtatta aatgataagc gagaagcatt tttttatgac atttttgcct tatcagatac
      721 tctaaaaatg ttgacattct tattactaga taatcccaaa cacaaatcaa tcgctgttta
      781 tacacgaaaa caagggatat cccagtcaaa agcttatcgt cttattcata aattaaaaca
      841 ttatttacaa gacattggtt taaatattgt agacaatact gttatcggag atgaacttaa
      901 aatacggtat ttgattgctc ttttacataa agagtacggc attatattat atgatataca
      961 acctgcagac attgaaacga ttcatgcttt tatctttgca gcacaaaaaa acttacaacc
     1021 ttctgccttt ttagatagac gcttcttgtt ttttgatgtg ctgttgatgt tgacttggaa
     1081 gcgccatcgc tatcctgttc atttgcctca tttagctctt tttgaacatc tcaaatcctt
     1141 gcctattttt gacaatatca aaaccattgc cgtggatgag ctagcacctc gaactcgtgt
     1201 cacattttcg tctgatgatt ttgactatct ctttttaatt tatttaacga ctgataactc
     1261 cttcttgagt gggtactgga caagtcatca gcgacaacaa ctttaccatt taatcaccaa
     1321 agatcccgat tatcatttac taatccatcg tcttcaggca ctagttggaa aatattccga
     1381 tattcatgag catatcccta acttaattcc ttttttcaaa agaactctct acaatttaca
     1441 aactttaatt acctttgatg gttattattt tgatcaatat caaggcaaca tgctactact
     1501 agataagctt gaaaccgtta tcaaagattg gctttatgac acaggccgtc aaggcagtat
     1561 tagttctggt cacttacact tgatgtgttt ataccttgag cagatcttgg aaagctctat
     1621 tgctccaatc aatattactg ttattgagag ccaagaaact gttggtaacg ttatagctaa
     1681 tttcatcacc tcaactatcc cttcttacaa agttaaactg tcacgggtca atatcttatc
     1741 tgataatatt tatccctatg ataaacctgt agatctggtt gtaaccagtc agaagctctt
     1801 gcctttctta aaagaactcg gtgtttttcc caaagagacc cgcttgtttg gtttgagttt
     1861 ggactgtatc caacagcagc gcgaagattt aatcaaaacc atcttagcct tgcaccagaa
     1921 ccactaccaa aaacgtttag aagaactttg gagagttcct tcttaatttt ttgacagtcc
     1981 ctcctagata ctttcacagt ctaggagggt ctttaaggtt gtcacttgca accttgataa
     2041 gctctctttt tagccattgc tatttgctta gaaacagaac tggaactgtt atagcggttc
     2101 aactcctctt gtaggatctt cttccctttt ttgaaggtct tatctgaaat ttggtataat
     2161 aaagtgcgct cccatgttct ggaagcgcac tttattatcc cttttactta accttgtatc
     2221 cactcgatga tggaagtgcc gccccaattc ttagattgct tggctaactt ttaagctctt
     2281 gtacaaggaa gaagtctttt tgactatctg ttgattagag gcgagcatta agctctgctg
     2341 ataatgcttc aaaacctggt tttccaagaa gcgcaaacat gttacgtttg taagcttcaa
     2401 cacctggttg atcaaatggg ttaacagcat tcatgtagcc tgaaacagcg atggcaagct
     2461 caaagaagta aatagtgtaa ccaagggtaa actcgtcttg agctggaaga gtgacaaaca
     2521 tgtttggcac gccgccatct gtgtgggcaa gaagcacacc atctgtagct ttcttgttaa
     2581 cgaaatcaac gtctttacct tgaaggtaac caagtccatc taggtcttct gctaattcag
     2641 gaatgataac atttttacga ggattatcaa cacgaataac tgtttcaaag agattacggt
     2701 aaccttcttg gataaattga ccaagtgagt gaaggtctgt tgagaagtta gctgaagttg
     2761 ggtaaatccc tttttgatct tttccttctg attcaccagc taattgtttc caccattcgc
     2821 caaagtactg aagagatggc tcgtagttag ccaagatttc agtgatgtag cctttacggt
     2881 aaagcacatt acgaacagca gcgtattggt aagcaatgtt ttcagagatt ttgtctgaag
     2941 aaaggtcttt acgagcagca tttgcccctt ccataagagc agtaatatct gcacctgatg
     3001 cagcaattgg aagcaaacca acagcagtca agactgagaa acgaccacca acattatctg
     3061 gcaccacaaa tgtttcccag ttgttagcgt cagcttctac cttaacagca cccttaactt
     3121 tgtctgtggt agcgtagata cgtttgttag cttcttcttg gccatatttt ttaaccaaaa
     3181 gttctttgaa cacgcgaaag gcaatagctg gttcagtggt tgtacctgat ttagagatca
     3241 cgtttactga gaactctttg tcttgaacgt attcaactaa atcggcaagg taagtagatg
     3301 aaatagagtt tccagcgtaa agaatttgtg gggctttgcg ctctttggca gtttgcaagt
     3361 tagcaaaatg atgatttaaa aaatcaatcg ctgctttggc accaaggtat gacccaccga
     3421 taccgatcac cacaagaact tcgctgtctg ccttaatctt ttcagcagca gtcaagatac
     3481 gtgcaaattc atctttatca tagttttctg gaagatcaag ccagcccaag aaatctgaac
     3541 ctggtccagt tccttcacgc aataacttgt cagcttctgt tacttggcct tgtaaaaaat
     3601 caatttcatg ttgtcccgca aatgactcga ggacttttga ataatcaaat gtaatatgtg
     3661 acatgagttt cgctccctta aaattttaag tttcattagt atgataacct tttctatcta
     3721 atatttcaat ggtttttagt ggttttcacc tgtgaaaaag ctaggttttt tgaaaaggtt
     3781 ttcgtttttt cagacataaa acatgtgtca atgcaagcat attctcatca tagtggtttt
     3841 ttaagagaaa ataggatttc atatttccta aaaatatcat gaaaaaaggc cctgaggccg
     3901 ctttaccgta ataacttatt ttaaggattt tatcatttca acacgggtaa taaccccatc
     3961 atgcatatga tcaatgcata aagccacacc tacaaaggca attgaagccc caatcacctg
     4021 taaatacttt ctcatgctat cttcttaaca ttacttactc tcattatcta aaaatggcaa
     4081 tcatttgaat acttaaaaag caaagggggg agaatagcac tagtgcgttt ttaagtagat
     4141 atcaaa
//
LOCUS       DAUGQX010000078         4101 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUGQX010000078 DAUGQX010000000
VERSION     DAUGQX010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4101
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.078"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..776
                     /locus_tag="VIA51_001694"
     rRNA            <1..776
                     /locus_tag="VIA51_001694"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            828..900
                     /locus_tag="VIA51_001695"
     tRNA            828..900
                     /locus_tag="VIA51_001695"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:861..863,aa:Ala,seq:tgc)
     gene            1199..4101
                     /locus_tag="VIA51_001696"
     rRNA            1199..4101
                     /locus_tag="VIA51_001696"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1149 a          856 c         1171 g          925 t
ORIGIN      
        1 agcgtgggga gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct
       61 aggtgttagg ccctttccgg ggcttagtgc cggagctaac gcattaagca ctccgcctgg
      121 ggagtacgac cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga
      181 gcatgtggtt taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgcc
      241 cgctctagag atagagtttt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc
      301 agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt
      361 gccatcatta agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg
      421 atgacgtcaa atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt
      481 acaacgagtc gcaagccggt gacggcaagc taatctctta aagccaatct cagttcggat
      541 tgtaggctgc aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc
      601 gcggtgaata cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac
      661 acccgaagtc ggtgaggtaa cctattagga gccagccgcc taaggtggga tagatgattg
      721 gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa
      781 ggaaatggaa cacgtttatc gtcttattta gttttgagag gtcttgtggg gccttagctc
      841 agctgggaga gcgcctgctt tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca
      901 tcaggataca atcctactaa acttaataca agtgaagttg aacacgcaac tcacttccta
      961 ggaaaatgga caatcttccc ttgtgtgcaa ggcccacatg gtcagattcc taattttcta
     1021 cagaagtttc gctaaagcga gcgttgctta gtatcctata taatagtcca ttgaaaattg
     1081 aatatctata tcaaattcca cgatctagaa atagattgta gaaaagtaac aagaaaataa
     1141 accgaaaacg ctgtgactat ttaataagtt ttctagttta aaaaaactag gttaataagg
     1201 ttaagttaat aagggcgcac ggtggatgcc ttggcactag aagccgaaga aggacgtgac
     1261 aaacgacgaa atgctttggg gagctgtaag taagcgctga tccagagatg tccgaatggg
     1321 ggaacccact aactaatggt tagtatccat aactgttaag gttatgagaa ggaagacgca
     1381 gtgaactgaa acatctaagt agctgcagga agagaaagca aacgcgattg ccttagtagc
     1441 ggcgagcgaa acggcaggag ggcaaaccga agtgtttaca cttcggggtt gtaggactgc
     1501 gacgtgggac tttaaaagga tagaagaatt acctgggaag gtaagccaaa gagagtaaaa
     1561 gcctcgtatt taaaattctt ttgagcccta gcagtatcct gagtacggcg agacacgtga
     1621 aatctcgttg gaatctggga ggaccatctc ccaaccctaa atactctcta gtgaccgata
     1681 gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg gaggggagtg aaatagaacc
     1741 tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg gtgagagcgt gccttttgta
     1801 gaatgaaccg gcgagttacg atatgatgcg aggttaagtt gaagagacgg agccgtaggg
     1861 aaaccgagtc ttaatagggc gatttagtat catgttgtag acccgaaacc atgtgaccta
     1921 cccatgagca ggttgaaggt gaggtaaaac tcactggagg accgaaccag ggcacgttga
     1981 aaagtgcttg gatgacttgt gggtagcgga gaaattccaa acgaacttgg agatagctgg
     2041 ttctctccga aatagcttta gggctagcgt cgatgttaag tctcttggag gtagagcact
     2101 gtttgggtga ggggtccatc tcggattacc aatctcagat aaactccgaa tgccaacgag
     2161 atatcatcgg cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag
     2221 accaccagct aaggtcccaa aataactgtt aagtggaaaa ggatgtgggg ttgcacagac
     2281 aactaggatg ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt
     2341 cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacag tttaccgaag ctgtggatga
     2401 cacaaaagtg tcatggtagg agagcgttct atgtgtgaag aaggtgtacc gtgaggagcg
     2461 ctggaacgca tagaagtgag aatgccggta tgagtagcga aagacaggtg agaatcctgt
     2521 ccaccgtaag actaaggttt ccaggggaag gctcgtccgc cctgggttag tcgggaccta
     2581 aggagagacc gaaaggtgta tccgatggcc aacaggttga tattcctgta ctagagtata
     2641 tagtgatgga gggacgcagt aggctaacta aaccggacga ttggaagagt ccggctaagc
     2701 agtgaggtgt aagatgagtc aaatgcttat ctttataaca ttgagctgtg atggggagcg
     2761 aattttagta gcgaagttag tgatgtcaca ctgccaagaa aagcttctag cgtttaatga
     2821 tactctaccc gtaccgcaaa ccgacacagg tagtcgaggc gagtagcctc aggtgatcga
     2881 gagaactctc gttaaggaac tcggcaaaat gaccccgtaa cttcgggaga aggggtgctg
     2941 acttaggtca gccgcagtga ataggcccaa gcaactgttt atcaaaaaca cagctctctg
     3001 ctaaatcgta agatgatgta tagggggtga cgcctgcccg gtgctggaag gttaagagga
     3061 gggtttagcg caagcgaaga tctgaattga agccccagta aacggcggcc gtaactataa
     3121 cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acccgcacga aaggcgtaat
     3181 gatttgggca ctgtctcaac gagagactcg gtgaaatttt agtacctgtg aagatgcagg
     3241 ttacccgcga caggacggaa agaccccatg gagctttact gcagtttgat attgagtatc
     3301 tgtaccacat gtacaggata ggtaggagcc attgacttcg ggacgccagt ttcgaatgag
     3361 gcgttgttgg gatactaccc ttgtgttatg gctactctaa cccagatagg ttatccctat
     3421 cggagacagt gtctgacggg cagtttgact ggggcggtcg cctcctaaag agtaacggag
     3481 gcgcccaaag gttccctcag attggttgga aatcaatcgc agagtgtaaa ggtataaggg
     3541 agcttgactg cgagagctac aactcgagca gggacgaaag tcgggcttag tgatccggtg
     3601 gtaccgaatg gaagggccat cgctcaacgg ataaaagcta ccctggggat aacaggctta
     3661 tctcccccaa gagttcacat cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat
     3721 cctggggctg tagtcggtcc caagggttgg gctgttcgcc cattaaagcg gcacgcgagc
     3781 tgggttcaga acgtcgtgag acagttcggt ccctatccgt cgcgggcgta ggaaatttga
     3841 gaggatctgc tcctagtacg agaggaccag agtggactta ccgctggtgt accagttgtc
     3901 ttgccaaagg catcgctggg tagctatgta gggaagggat aagcgctgaa agcatctaag
     3961 tgcgaagccc ccctcaagat gagatttccc atgattttat atcagtaaga gccctgagag
     4021 atgatcaggt agataggtta ggagtgtaag tgtagcgata catgtagcgg actaatacta
     4081 atagctcgag gacttatcca a
//
LOCUS       DAUGQX010000079         4037 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUGQX010000079 DAUGQX010000000
VERSION     DAUGQX010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4037
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.079"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..58
                     /locus_tag="VIA51_001697"
     CDS             <1..58
                     /locus_tag="VIA51_001697"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEQ8683622.1"
                     /translation="LLSFKVVQELSAVDWWRL"
     gene            105..1103
                     /gene="ruvB"
                     /locus_tag="VIA51_001698"
     CDS             105..1103
                     /gene="ruvB"
                     /locus_tag="VIA51_001698"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEQ8683623.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            1241..1678
                     /locus_tag="VIA51_001699"
     CDS             1241..1678
                     /locus_tag="VIA51_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEQ8683624.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            1701..2102
                     /locus_tag="VIA51_001700"
     CDS             1701..2102
                     /locus_tag="VIA51_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683625.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKDGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            2099..3874
                     /locus_tag="VIA51_001701"
     CDS             2099..3874
                     /locus_tag="VIA51_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEQ8683626.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLFWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMIGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGSLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSQIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
BASE COUNT         1232 a          631 c          835 g         1339 t
ORIGIN      
        1 tctactatct tttaaagtag ttcaagagct tagtgctgtt gactggtggc gattataata
       61 aaagtaggcc actgctctct tttactttat gttataatag tcttatggct agaattttag
      121 acaataatgt aatgggaaat gaggagtttt cggatcggac tcttcgccct caatatctac
      181 acgaatatat tggacaagat aaagttaagg aacaattcgc tatttttata gaagcagcta
      241 aaagacgtga cgaatcttta gaccatgttt tattatttgg acctccagga ctgggaaaaa
      301 caacaatggc atttgtgatt gccaatgaat tgggagttaa tttaaagcaa acttcaggtc
      361 ctgccgttga gaaagctgga gatttggtag ctattttaaa tgaattagaa ccaggggata
      421 ttttgtttat tgatgaaatt caccgcatgc caatgtctgt cgaggaagta ctatatagtg
      481 ctatggaaga cttctatatt gatattatga ttggcgctgg agatactagt cgtagtattc
      541 atttggatct gcctccattt acattgattg gtgctactac acgtgcaggc atgttatcta
      601 atcccctcag agctcgtttt ggtatcactg gtcacatgga atactatcaa gaaaaggatt
      661 tgacagagat tgtggagcgt acagctacta tttttgaaat aaaaatagac catgaagctg
      721 cacggaaatt agcttgtcgc agtagaggaa cgccccgcat tgctaatcga ttactaaaac
      781 gagtgcgtga ctatgctcaa attattggtg atggcatcat aacggctcaa ataactgata
      841 gagctttgac tatgttagat gttgaccgcg aaggtctcga ttacattgat cagaaaattt
      901 tacgaacgat gattgagatg tatcagggag ggccagttgg tttggggaca ttatctgtga
      961 atattgccga ggagcgtaat acagttgaag agatgtatga accctactta attcaaaaag
     1021 gctttctcat gcgaacacga acaggtcgtg tagcgacgca aaaggcttat cgtcatcttg
     1081 gctatcccta tcaaaacact taatgatttt tcaaatctaa gaaaattaat ctgaacctgc
     1141 tttttgtgtt cggatttttt gataagttga cagaaaatta ttagattgat ttctccgata
     1201 tcagttagaa atttgatata ataattcaaa ggagtattta atgaaaaaag tatgttttgt
     1261 ctgtctgggt aatatttgtc gaagccccat ggctgagttt gtaatgaagt caatagtatc
     1321 aagtgatgtt atgatgatag aaagtcgtgc tacttctgat tgggagcatg gaaaccctat
     1381 tcactcaggt acacagtcca tattaaaaac ttaccaaatt aattatgata taactaaatg
     1441 ctccaagcag ataactataa ctgattttaa cacctttgac tatattattg gtatggatag
     1501 cgataatgtg aaaaatctca aagagatgtc gcaacatcaa tgggactcta aaatctacct
     1561 gtttagagaa gggggtgttc ctgatccttg gtacactaac gattttgaag aaacctacca
     1621 attagttaga aaaggatgcc aggattggct ttctcgttta atgagtaaag agtattgata
     1681 ttagaagttg agtaaaagaa atgatagata tgcaagatat agtaaaaaaa tggagtatta
     1741 cacgggcgaa gttggaaatt gtctcggtga ttgtcatatt ggtttgtgca atttctgttt
     1801 ttagcgtaag aatttcgaat aagacaagtt tgacctatga taaagggcgt atgcactata
     1861 ctggttacgt gattaaccat aaaatgaatg gagaagggaa gcttgtctac cccaacggtg
     1921 atatctatga gggtactttt aaggatggcc tatttgaagg aaaaggaact tttactgcta
     1981 agacgggctg gttatataac ggggagtttc ataaaggaca agcaaatggc aaaggtgtgt
     2041 taaaagcaaa gaataataaa gtctataaag ggatttttaa acaggggata tttcaaaaat
     2101 gagaataaaa tggttttcgt ttgttagggt aacaggactt ttactggttt tactctacca
     2161 cttttttaaa aatgtatttc caggaggttt tattggtgtt gacattttct tcaccttttc
     2221 aggatatcta atcacagccc tcttgattga tgaatacaca aaaaaagagt ctatcgatat
     2281 tatcggtttt ttaaaaagac gcttttatcg aattgttcct cctttggtgt taatgatttt
     2341 attgaccatt ccttttacgt ttttaattaa gaaggatttc attgctaata taggaagtca
     2401 gattacagct gttttaggat ttaccactaa tatttatgaa atattgacgg gaagtagtta
     2461 tgaaagccaa tttattccac atctctttgt tcatacgtgg agcttagcta ttgaagttca
     2521 tttttacttg ttttggggtg tatttgtttg gttattagct agacgcaagg agactcagaa
     2581 acaactgaga ggactactgt ttttgatttc tttgggaata tttgctatta gtttcttgag
     2641 catgtttata agatctttta tgacctcaaa tttttccctg atttattttt cgagtctttc
     2701 tcacagtttt cccttctttt taggggcgat gtttgccacg ataacaggta ttaacgagac
     2761 tactgttcga tttcaaaaaa atgtacgttt atggccgcgc cagtatgtcc ttgctgctat
     2821 gattggagca tttacacttt tgcttgtgct aacggtcaca ttggatttta accatatcac
     2881 gacctatcta tttggctttg ctttggctag cttattcgca tcaattatga tttatgcagc
     2941 gcgtgttctt catgagcaaa caccagatgt acaagagcct aaagctatca cttatatagc
     3001 tgatattagc tatgggattt acctcttcca ttggccattt tacattattt ttagccaatt
     3061 aatgtctcat attttggcag ttattctaac agttttcttt tcaatcttgt ttgccactgt
     3121 gtcttactat attgtggaac ctttggtcca agggagaaaa ccaaacctgc ttggtttaga
     3181 aattgactgt tctccttact ataagtggat tgtaggaggg tctctcgcct tagcattatt
     3241 aactttagga acttgtatga tagcgcctaa agttggtaag tttgagaaac aattgttggt
     3301 cagttcccta caacaggctc aaagtaatat ggagcggaca catacactag ctgcaggaga
     3361 cgctaatgct ttgagtgacg taggtattat tggtgattct gtagcattac gctctagtgc
     3421 agcattctca caaattatgc cacaagcgca actggatgca gcggtcagtc ggaattttaa
     3481 agaagctttc gatttattta ataaccaaat taaatctaag agtctatcta agactgttgt
     3541 cttagcagta ggtgttaact cgcttgacaa ctattctcaa gcagttcagt cttttattga
     3601 ggcattgcca aaaggtcatc gtttagtttt ggtttctcca tataatgcca aaaatgccag
     3661 tcaggttgca gaagctagag actatggtct taaattgtcc aaaaaataca agtatgtcac
     3721 tattgcagac tggtataaag ttgctgttga acatccagat atttggtatg gcagtgatgg
     3781 tgttcattat agtgaagata gtcaaggagc agaactatat gtctccacaa tccagactgc
     3841 tgttgagaag tcagctaaaa aaccagctaa ataaagttaa aaaatgtcta agagataagt
     3901 cagatccatt gtgctctggc tttttcttgt gaacaaatga tgatggtaaa atagtagtac
     3961 tttgaggttt ttaaaagaaa gcggtttcag aaataaaacg gcttttttta gatatatttc
     4021 tgaaaaaaag ttaatga
//
LOCUS       DAUGQX010000080         3251 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUGQX010000080 DAUGQX010000000
VERSION     DAUGQX010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3251
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.080"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..922
                     /locus_tag="VIA51_001702"
     CDS             <1..922
                     /locus_tag="VIA51_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8683627.1"
                     /translation="KFFEENYSQEIPTRIKNLRKKHNITQSELGNAGQVSQVESGKRP
                     ITSSMLVYLNALTASNYTYIVFGELDEFIENLFHYFFSSILYRDLEAVDENLYSFMSD
                     DLISIQSSCLSIAKTFANFNIQRKRFMISTETEMDTFHKKDDIDVWVGGKSYNPARSF
                     RNNPINELTVIDFEEMADILLLMLRDNLIRSFEINVCNTLFELDKNGEPTTFNLDKID
                     SIINKWWSENVSTEIIPNLIKKLRENPLFNIGFMVNDILERMYKEDIPKSYLTSVPLV
                     ISKKARSTLSIKSNGSQKIDKSKFAQILSL"
     gene            988..1740
                     /locus_tag="VIA51_001703"
     CDS             988..1740
                     /locus_tag="VIA51_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8683628.1"
                     /translation="MAIPDLDKFSSNLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPKSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            1737..2339
                     /locus_tag="VIA51_001704"
     CDS             1737..2339
                     /locus_tag="VIA51_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683629.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(2815..3096)
                     /locus_tag="VIA51_001705"
     CDS             complement(2815..3096)
                     /locus_tag="VIA51_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8683630.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR"
     gene            complement(3103..3153)
                     /locus_tag="VIA51_001706"
                     /pseudo
     CDS             complement(3103..3153)
                     /locus_tag="VIA51_001706"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
BASE COUNT         1084 a          607 c          531 g         1029 t
ORIGIN      
        1 gaaatttttt gaagaaaatt attcacaaga aatacctact cgtatcaaaa atttaagaaa
       61 aaaacacaat attacacaaa gcgaactagg caatgcaggt caagttagtc aagttgaaag
      121 tggtaagcga ccaattacga gttcgatgtt agtttattta aatgctctaa ccgcttcgaa
      181 ctatacgtat atcgtttttg gagagttaga tgagtttatt gagaatctgt ttcattattt
      241 tttcagttct attttatata gagatttaga ggctgtagat gaaaacctat attctttcat
      301 gagtgatgat ttaatttcaa tccaatcaag ttgtctaagt attgccaaga catttgcaaa
      361 tttcaatatt caaagaaaaa gatttatgat ttctactgaa actgaaatgg atacttttca
      421 caagaaagat gacattgacg tatgggttgg tggaaaaagt tataaccccg ctaggagttt
      481 taggaataat ccaataaatg aattaactgt tattgatttt gaagaaatgg ctgatattct
      541 tttgttgatg ttgagagata atctaattag gtcgtttgaa attaatgtct gcaacacact
      601 gttcgaatta gataaaaatg gtgaaccgac aacatttaat ctagataaaa ttgactcaat
      661 aatcaataag tggtggtctg agaatgtctc aacagagata atacccaacc tcataaaaaa
      721 acttagagaa aatcccttgt ttaatatcgg atttatggta aatgatatat tagaacgaat
      781 gtataaagag gacataccaa agtcttacct tacttctgtt ccattagtta tttccaaaaa
      841 agcaaggtca actttatcga ttaagtcaaa cggaagtcaa aaaatagata aatcaaaatt
      901 tgcacagatt ttgtcccttt agagacggat gacttacaca ttcaacgtgg attattcttc
      961 ccttggagaa aggggatttc agaacgcttg gcgattcctg atttagataa attttcatct
     1021 aacttacaac aggggaaaat tcctgtcata aagcacttcg aactcaattt agataagggg
     1081 agtcactggg ctattgctgg aaattcaggt tctgggaaac cgtacgctct cacttacttc
     1141 ttgagtgtcc tgaaacctaa gtccggccta attatcattg acccaaaatt cgatacccct
     1201 agccaatggg caagagaaaa taaaattgcc gttatccacc cagtagaaaa ccattcaaaa
     1261 tctgatttcg tttcacaagt caatgaacaa ttaaaccagt gtgcaactct cattcagaaa
     1321 cgacaagcta tcttgtatga taatcccaat catcaattta cccatctaac tattgttatt
     1381 gatgaagtcc tcgctctatc agagggagtc aataagaata tcaaagaagc ttttttctcc
     1441 ctactatcac aaattgcctt gttgggacat gctactaaaa tccatctatt cttgggaagc
     1501 cagcgttttg accataacac tattcccatt tcagtgaggg aacagctaaa cgtattattg
     1561 caaattggaa atatcaatca gaaaaccact caattcttat ttccagacct agatccagag
     1621 ggaattgtca ttccaacagg acacggaaca ggtatcattc aagttgtcga taatgaacac
     1681 tcctatcaag ttctaccctt actctgtcca acctactata ctaagcgagg tatcctatga
     1741 ccactaaaac ctacttcatg agaagcttca atctcatatt atacttactg cttattgctc
     1801 caatctgcta tgtgttcggt tggctgttca atcttgtttc agttcaatta tctaccgtca
     1861 catttgtcaa tctggatacg gttaaaaacg ttactgatac cattagttct gtatgttatg
     1921 gattcgctct tatttcttta cttctagcct tattatctgg attaaagatg atacaacgct
     1981 tgaatacaga tagccttggg aactactgcc aatctattta tcgcaccttt ctattaagac
     2041 acttcctttt ccagcgtgaa cgagtacaga aggtaagcaa ctttgaacac cagaccgtta
     2101 ccactatcaa tccaatccat aacgggttta accgagctgt acgtaagtgt atcgtagata
     2161 tacgaaaaga tgccattact gtatttctaa aagttcctag agaccaacag gggcaaaaaa
     2221 tcctaaagga tacgggagta caactgaaag aagagattgt catccaacac acagactatt
     2281 atttctcttc tcctgttcga gttcgtaacc aattgtggtt tattggtcaa aagcgttaat
     2341 tccttggggc tgtggcttgc gttaagcaaa agccagacag cccctttttt atattcttat
     2401 ctatcatgac ctattggggt tactacgaca acgaaagtta gaagctgtgg gtatttattt
     2461 atcttgaaaa gattgctgaa ctaacgcaat aactactcta ccattcactc taccttttat
     2521 taagcaacta tcaataaata ttgatacaat aaggtttata acagctaaaa tagaaaatac
     2581 ttaaccttta cagaagtaaa ataattgaga tgagaaaagc ctatgaaatg aacgtttcaa
     2641 aggctttttt cgtgtttaaa aaaacaaatg aaaaaacaaa atagagagta gggttattaa
     2701 cactgtcagt cctgtgtacg caataacaat ccatgctttt tgataaggat attttgcttt
     2761 ttctttaatc ttatcaatct gatctaagct ctcacccttt gctatagctt caagttatcg
     2821 gtaagtctga acatcatatg tctttttaaa tcgctcaatt cttaaggcga tacgcatgat
     2881 tatcaaccat aagatagcaa ccggaccata tccccaccaa cctaaccaag acattatagg
     2941 ataaatactg atagcaatta ggagtgtccc aaataacata atatgcgtat tcctatcaca
     3001 ttgtttaatc tcctcatcct taataattaa agtcattttt gggatatctt ctgctattag
     3061 ttgctctaaa ggaacctgta aggacttact taacatcaaa agattttgca ggtctggata
     3121 gcttttaccg ttttcccagt ttgagatagt cttcttgaaa catacatcat ttcagcaagc
     3181 tcttcttgtg acatctgtaa tttttttcaa taataagata actggttttt aaagcccata
     3241 ataaatctcc t
//
LOCUS       DAUGQX010000081         2726 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUGQX010000081 DAUGQX010000000
VERSION     DAUGQX010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2726
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.081"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..465
                     /locus_tag="VIA51_001707"
     CDS             <1..465
                     /locus_tag="VIA51_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8683631.1"
                     /translation="ASLQIFNIKDYNLDNLLENPNKFDDEKYWITVDTYSAQGERATA
                     FSNTLNNITSKYWRVVFDTKGDRYSSPVVPELQILGYPLPNADTIMKTVTTAKELSQQ
                     KDKFSQKMLDELKIKEMALETSLNSKIFDVTAINANAGVLKDCIEKRQLLKK"
     gene            729..1613
                     /locus_tag="VIA51_001708"
     CDS             729..1613
                     /locus_tag="VIA51_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8683632.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIART
                     IAYFKAFEADLAGMAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTALLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            1708..2661
                     /gene="manA"
                     /locus_tag="VIA51_001709"
     CDS             1708..2661
                     /gene="manA"
                     /locus_tag="VIA51_001709"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEQ8683633.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
BASE COUNT          836 a          473 c          614 g          803 t
ORIGIN      
        1 gcaagtctac aaatttttaa tatcaaagat tataatctag ataatttgtt ggaaaatccc
       61 aataaatttg atgatgaaaa atattggatt actgtagata cttacagtgc acaaggagag
      121 agagctactg cattcagtaa tacattaaat aatattacta gtaaatattg gcgagttgtc
      181 tttgatacta aaggagatag atatagttcg ccagtagtcc ctgaactcca aattttaggt
      241 tatccgttac ctaacgccga cactatcatg aaaacagtaa ctactgctaa agagttatct
      301 caacaaaaag ataagttttc tcaaaagatg cttgatgagt taaaaataaa agagatggct
      361 ttagaaactt ctttgaacag taagattttt gatgtaactg ctattaatgc taatgctgga
      421 gttttgaaag attgtattga gaaaaggcag ctgctaaaaa aataaacaaa gtaactttct
      481 tagatagcaa cattcagatt aaattaacaa aatgtgacta tgataaaggt ttgctggaat
      541 tgattaacca aaagactaaa aatctgagat gaatagtccc agatttttag tcttttatag
      601 gttttgatga cataaagcta aataatcgtt agactaccag aaagtggcgc ttgtccgtga
      661 gacatggctg tcttgataag agcctgtgtc atcataaaga taaaaaagaa caagaaaaag
      721 gagaaaacat gggaaaatta tatggaagca ttgaagctgg tgggacaaag tttgtctgtg
      781 ccgtgggtga tgaggagttt acagtggtgg ataaaacaca atttccgacc accacaccag
      841 aagaaaccat cgcgcgaacc atcgcttatt ttaaagcttt tgaggcagat ttggctggaa
      901 tggcgattgg ttcttttgga ccaattgata ttgatccgtc gtcagagact tacggttata
      961 tcacaaccac tcctaaatca ggctgggcta atgtggattt gttaggacaa ctttcggctg
     1021 cttttaagat tccttttgat gtgacaacag atgttaatag ctctgcttat ggtgaggtgc
     1081 ttgctcgtcc tggtgtggaa agtttggtct attacaccat aggtactggt attggggcgg
     1141 gagctattca acatggccac tttattgggg gtttaggtca tacagaagcg ggtcatacct
     1201 atgtcatgcc ccatcctgat gatatggcca agggattttt aggtgtttgc ccttttcata
     1261 aagggtgtct ggaagggatg gcagcaggtc caagtattga ggccagaacg ggagtgagag
     1321 gtgaacggct tgatcaggaa gctgatgttt gggacattca agccttctac attgcccaag
     1381 cagcgctgca agcaactatg ctttaccgtc ctcaagtgat tgtttttggc ggaggtgtca
     1441 tggcgcaaga acatatggtg ttgcgcgtgc atgataaatt cactgccctt ttaagcggtt
     1501 atttgccagt ccctgatttg acagactaca ttgttactcc agctgttgct gataatggct
     1561 ccgctactct gggaaatttt gctttggcca agttggctgc acaaggaaaa tagggtctgt
     1621 ttttgcctgc ttgtctagta aaagaaagcg cagtcagcta gaacatgcta taataaacag
     1681 agattaacat cagaagcgag gaatattatg tcagaaccat tatttctaaa atcaaccatg
     1741 cacgacagga tttggggtgg caccaagttg agagatgtct ttgcttacaa catcccaagt
     1801 gacaccacag gtgagtattg ggctatttct gctcatccta atggtgtttc gacagttact
     1861 aatggacgtt atcaaggaca acctttaaac acattatatg cgcaagagcc ggccttgttt
     1921 gggaatccaa aggaagaagt ttttccactg ttaactaaga ttttagatgc taatgactgg
     1981 ctaagtgtcc aagttcatcc tgatgatgct tatggacgtg aacatgaagg agaattaggc
     2041 aagacagaat gctggtatat tatttctgcc gaagagggtt ctgaaattgt atacggccat
     2101 caggccaagt ccaaagaaga ccttcgtgcc atgattgaag caggcgcttg ggatgatttg
     2161 ctgactcgtg tcccagtcaa agcaggcgat tttttctatg ttccaagtgg caccatgcat
     2221 gcgatcggca agggaattct tattttagaa acccagcagt catctgatac cacttatcgg
     2281 gtttatgatt ttgaccgtaa ggacgttaat ggtaatcttc gtgaccttca tattgaaaag
     2341 tctattgatg tcttaacgat tggtaagcca gaaaatagcg tgccagccac tatggttttg
     2401 gataatatgg tagcaacaac tttagtctca acaccatttt tcactgttta caaatgggta
     2461 actagtcaaa tggttgacat gaaacaagct gcgccttatc ttttagtgag tgttttaaaa
     2521 ggtcaaggaa aactctatgt ggaccagaag gcttatgagc tagaaaaagg catgcacttt
     2581 atcttgccta acgatgttaa atcgtggtca tttgatggtc aattagaaat gattgtgagt
     2641 caccccaatc aactcgttta ataccatggt atcaatatga gaaaaaagga taaaattatg
     2701 actctctgtt tctctgataa ctttac
//
LOCUS       DAUGQX010000082         2687 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUGQX010000082 DAUGQX010000000
VERSION     DAUGQX010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2687
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.082"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(119..313)
                     /locus_tag="VIA51_001710"
     CDS             complement(119..313)
                     /locus_tag="VIA51_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ8683634.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIP
                     WQGYILCGAAGAATNIIWPH"
     gene            complement(607..807)
                     /locus_tag="VIA51_001711"
     CDS             complement(607..807)
                     /locus_tag="VIA51_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8683635.1"
                     /translation="MTTMKELTINDMSSISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            complement(820..1036)
                     /locus_tag="VIA51_001712"
                     /pseudo
     CDS             complement(820..1036)
                     /locus_tag="VIA51_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
     gene            1354..2040
                     /locus_tag="VIA51_001713"
                     /pseudo
     CDS             1354..2040
                     /locus_tag="VIA51_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2231..2413)
                     /locus_tag="VIA51_001714"
     CDS             complement(2231..2413)
                     /locus_tag="VIA51_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8683636.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
     gene            complement(2428..2673)
                     /locus_tag="VIA51_001715"
     CDS             complement(2428..2673)
                     /locus_tag="VIA51_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ8683637.1"
                     /translation="MIKFAEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGA
                     GMATLGVGGVAGAFAGAHVGAIAGGLTCVGGMLFNGK"
BASE COUNT          892 a          579 c          365 g          851 t
ORIGIN      
        1 agaaataaga cgacctaatg ataaaatcat tcctattgta tagcaaacaa caatatctaa
       61 agttttcata ccactcctct actacttata catcagtgat agatagtcat ttatatattt
      121 agtgaggcca gataatattt gtagcagcac cagctgctcc acacaaaata taaccttgcc
      181 aagggataaa tacgcctgtc tgagcacaaa ctgtcactcc ctgcgcagca cctgccatcc
      241 ctgtcaaaaa gatatttgct ccgtcttttc cgcctccatt tatgatagcc agaccatttt
      301 ttagcacttc catatttttg aagtcttttt cattttaatt tcactctttt gtattttaaa
      361 aagctaagag tgatatctaa attcattggc ataatcacta ttttctttta tcgataaaaa
      421 caaataatga cgctaccaaa gctacgatag ataacatgtt taccgatttt tccgaaaggg
      481 ataattgatt gaaaattaaa aacactaaat atggtataga tttatcaaca tttttttatg
      541 aatggcatca acaatcatta aaaacattat agacgcatgc ataataataa aaatcgtata
      601 gatcatttaa tttgctgtat atcccaaata tgctccacca actgtaaatc ctacaacaca
      661 tccacctgtc aatactggat gtggcagttt acaaaatttc aatccagaag ctaagcctcc
      721 aagaccacca attacagcat ctcctggagc gtttcctcca cttatactag acatgtcatt
      781 aattgttaat tccttcattg ttgtcatcct ttccttcctc tagaatccgc ctgtagctcc
      841 tgttacacca gcccaaagag taatagctgt tttagctcca ggctacaccg caaactggaa
      901 aacctatagc agctccagca ctacctgcag cgataacccc actgacattt gcctgccaat
      961 tattcttacc accctcaacc ttggcaagct tttctatagt catttggtga aatgtttcca
     1021 gtttctttat ctccatatcg aataacttct tttcataatt cttaaatttg tctcgttgca
     1081 acctcgagct agtacagaat atcataaaga acagtatcat ggtttcaaaa tcttaaaagg
     1141 ctatttttca tcatgaaatg tctttttatc ctctctacac ttacgctgtg acaatagtta
     1201 attaattaag aagtttaaat gataccattc atgcttttat aaataccttt taagattttt
     1261 gatggtagtg taaaatatct tgtgtaaaca cacaaaaagg aataaatcct gtatagtaga
     1321 gttgcgacac ttactagaaa gagatttatt cccatgactc agtttaccac agaattactt
     1381 aacttcctag cacaaaaaca agatattgat gaattctttc gctcctcttt agaaatagct
     1441 atgaatgacc tcttgcaagt tgaactatca gcttttcttg gttatgaacc ttatgaaaaa
     1501 gaaggttaca acacaggtaa tagccgtaat gggacttatt ctcgtcagtt tgaaacaaag
     1561 tatggcttag tcaatttaat catcccaaga gatcgaaacg gcgagttttc accagtttta
     1621 ttaccatctt atgctagacg agaggaccac ttggaagaga tagtgatcaa actctatcag
     1681 actggcgtta cgacacgcga aatcagtgac attattaagc gcatgtatgg tgaccacttg
     1741 tttctgagtg gaagcctcgt tacaaaaagg ttatgacatc acttgaaaca acggaaaatc
     1801 tcctaacttt ctatcaattt ccacattaca tttggtctag tatttactct acaaacttga
     1861 ttgaatcact caataaagaa atcaagcgac aaagcaagaa ggagggtggt ttttccaaat
     1921 gaagaagcct tagaacgatg tcttgtaagt attttcgagg actataatat taagttcgga
     1981 gctcgtattc ataaaggatt cggagcatgc tttgacacac ttgatagttt atttgactaa
     2041 tattcaaaaa ctctactctt gtgtttacac aacattttaa tattattaat ttgtaatagt
     2101 acttagtaag acataaacaa atatcacaat taaaattact ttacttgcat tttctcttac
     2161 ctctttatcc ttcaaaaaaa tttgggaaag tattagacaa attaaaccga gtattataac
     2221 tataatcata tcattgataa gctgcaattc cagatgctac acatacaaat gctgccgcac
     2281 ctccagttat tggacctcct gctgcagcta taagcatccc acctaagcac cctccgatag
     2341 cagatccaat atttcctttt ccaccagaaa tatttactaa ttcttcaaac tgtaattcta
     2401 aaaaattatc catttttcac ctcaaaatta ttttccatta aataacatac caccaacgca
     2461 agttaatcca cccgcaatag cacctacatg tgcacctgca aacgcacctg caactcctcc
     2521 aacacctaaa gtagccatac ctgctccaac accacctgca atagcacctg aagtaatacc
     2581 accaattaaa tgatttttac aatctgtagc actataacct ccaataatat ggaacaactc
     2641 ttctttttgt atttcttctg caaattttat cataacttta aaaacct
//
LOCUS       DAUGQX010000083         2668 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUGQX010000083 DAUGQX010000000
VERSION     DAUGQX010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2668
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.083"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            52..666
                     /locus_tag="VIA51_001716"
     CDS             52..666
                     /locus_tag="VIA51_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEQ8683638.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEVPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
     gene            complement(1079..1951)
                     /gene="sdaAA"
                     /locus_tag="VIA51_001717"
     CDS             complement(1079..1951)
                     /gene="sdaAA"
                     /locus_tag="VIA51_001717"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEQ8683639.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKEQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIDSQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(1963..2634)
                     /gene="sdaAB"
                     /locus_tag="VIA51_001718"
     CDS             complement(1963..2634)
                     /gene="sdaAB"
                     /locus_tag="VIA51_001718"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEQ8683640.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMGTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
BASE COUNT          840 a          496 c          498 g          834 t
ORIGIN      
        1 gtaataatta aaagatatta tggataacgg agaaaagtga ggtattattg aatgtttaag
       61 aaagaaaatt taaaacaacg ttattttaat tttggattag tagcgttagc tctaacaata
      121 ttagccatca tttttgcctt ctcaagtaaa aatgctgata ctaagtctta tgctaagaag
      181 tcagaaagta aaatggtaac aatcgacaag gctccaaaaa ataatcatgc tattactaaa
      241 gaagaaagca aagaaaaagc aaagagcatt gcttcggagc ctattcccac agtagaaaac
      301 tctgtagctc cgacagtaac agaggaagta ccggttgttc agcaagaagt gactcaaact
      361 gttcagcagg tatcttcagt agcctataat ccaaacaatg tggtactttc caatggaaat
      421 actgctggta ttgtaggaag tcaagcggcg gcacagatgg cagcagcaac aggtgttcca
      481 caatcaactt gggaacatat aattgcgcgt gaatctaatg gaaatcctaa cgcagctaat
      541 gcttctgggg catcagggtt gttccagaca atgccaggtt ggggttctac agcaacggtt
      601 gaagatcaag tcaatgcagc cttgaaagcc tatagtgcac aaggtttatc agcttggggt
      661 tactaaataa acatggctgg aagaaataaa acctattgtt agtatttact aacaataggt
      721 ttttggtatt taattgtctt tatgatttgt agtgatgaat tagtctcaaa acaaaacatt
      781 gccttatcgg gaatatagct cgtattattt aggaaaactg accagcactt aagtgcctct
      841 gatatttaag gcagttatac tgataacaag caggaaaaaa actcttaaat gtttataagg
      901 tcattagcaa ttttcagtat tttacactac tacacttttg agttttaaca atttactaga
      961 agttgtttct aaggggaaac aacatagctt gatagctatc tattagtcat tttagtgaat
     1021 atatagcaga aaaataaaac gctttcaaat atttctaaga atttttctaa ctatctattt
     1081 attcgccaaa tatttctacg ctgtaacgtc gtccagttgg agtagcggct aaaccacctt
     1141 ctgctgtttc acggaaagca gttggcatgg cagagccgac ttgatacata gcatcaataa
     1201 cttcgtcaac aggaatttga gaatcaatat cagctaaagc catatcagct gcgacaaggg
     1261 cgaaacttgc tcctagggca ttgcgtttga cacaaggcac ttctactagg ccggcaacag
     1321 gatcacagac aagtcctaat aaatttttga taacaaacgc aatagcttga ctagcttgat
     1381 gagatgttcc accggctgct ttaacaagag cagctgcact catagcagct gcagaaccaa
     1441 cttctgcttg gcatccacct tctgcaccag aaatagaggc gttatttcca ataacaagac
     1501 caaaagctcc tgcagtaaat aaaaactcta attgttcttt ttctgataag tcaagttttt
     1561 caatagctgt tgcgagcact gctggtaagc atcctgcact tcctgcagtg ggtgttgcac
     1621 agacaagtcc cattttagca tttaattcgt ttacagctat agcatttcta acagcattaa
     1681 gaatagtagt atcagaaagg ctgttccctt ttttaatgta gttatccatt ttgaccgcat
     1741 cgccccctgt caaaccactg atagatttgg ttgaggttag tccttctgtt acagctgctt
     1801 tcataacttg taaattgcgt gacatgattt tgataatatc ttctcgattt cttccagaca
     1861 tctccacttc cgtggcaatc atgagttcag caatatttcc attaaattgt tggtcagctt
     1921 gtttgacaag ttcttcaata gtataaaaca tagctttcct ttctagtcaa agaagttgac
     1981 attataaata tgaggaattt ttgcaatttg gttggctgct tcttggcact ctctagaatc
     2041 gacttctata atcatagtag ctttttcacc agcggattca cgtgtaacat tcattgtggc
     2101 gatattaata ttattggaag ataggatatc agttaccttt gcgatcattc cgggaatatc
     2161 tttgtgtaca gtaactatag taggagtatt catggataac gagacagaaa aaccatttag
     2221 ttctgttact tgaatgtttc ctcctccaat tgaaacacca gtaacactaa gtgttttgtc
     2281 agcttttttg acactgattt taacagtatt gggatgggga gcattactat cttttaagat
     2341 atcccaatag atttttatcc ctttttgatg agcaatttct agagaatttt taatatcagg
     2401 attatcagta cccataccca taattcctgc aacaagagcc ttatcagtac catgtcctct
     2461 gtaggtttta gcaaatgaat tataaaggtg aaacgtcact tcatcaggaa tatctccaaa
     2521 gatggaatgg actaccttac caattctgac ggcaccagct gtgtgactac ttgatggacc
     2581 aatcattact ggcccaatga tgtcaaaaac tgattgaaat ttttgtgtat tcataggcaa
     2641 ctccgttttt tatttctatg tttattat
//
LOCUS       DAUGQX010000084         2654 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.084, whole genome shotgun sequence.
ACCESSION   DAUGQX010000084 DAUGQX010000000
VERSION     DAUGQX010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2654
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.084"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..1328
                     /locus_tag="VIA51_001719"
     CDS             <1..1328
                     /locus_tag="VIA51_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AIPR family protein"
                     /protein_id="HEQ8683641.1"
                     /translation="KFIKGVKKITTSDFSNFNDLIVAKQKEIEKALSDFNYRIEIIVC
                     TSSNQNISSNSQEVIDDFLQGVNSDGSDDVVTYRHIKLNDVYDHMANQGVAPKIDFED
                     VVVHNWGRPTLYNDSYKVYYGWLSATDIVNWKEQYGDRIFEKNIRNFKQNTDVNNGIK
                     IISEKVEKNLKGVSTTDYINLKLIGASIINGAQTTGSLFEAYHSEDIDLTNVSVQVQI
                     IVLGEDIDNIGPKITKLSNTQNRIENKDFAAQDKEQERLMKDLAIDGKQYVYRQGVEL
                     PNSDEGCDLDSATVALGCYLDDVAISTQMKRAYGSIFDNTNKPPYKLIFNSGTSAYKL
                     WNCVEVYRELQNIEGEYQQDPNNQSKKLMSIHGNRFILHLIFQKLKNNPSLDFENGYI
                     TTFPNLTEEYCLIMEELIRAKEELYPEAYPANIFKNGKRTKELKEKMSF"
     gene            1346..2638
                     /gene="purB"
                     /locus_tag="VIA51_001720"
     CDS             1346..2638
                     /gene="purB"
                     /locus_tag="VIA51_001720"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEQ8683642.1"
                     /translation="MLERYSRPEMAAIWTEENKYHAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDTKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
BASE COUNT          905 a          421 c          565 g          763 t
ORIGIN      
        1 taaaatttat taaaggggtt aaaaaaatca ccacttcaga tttttcaaat tttaatgatc
       61 tcatagtagc aaagcaaaaa gaaatagaaa aagctttatc agattttaat tatcgaatag
      121 aaattatagt ttgtacttcc tctaatcaaa atatatcttc aaatagtcaa gaagtaatag
      181 atgatttttt gcagggtgta aattctgatg gtagtgatga tgtagtaaca tacagacata
      241 taaaacttaa tgatgtttat gatcatatgg ctaatcaagg agtggctcct aaaatagatt
      301 tcgaggacgt tgtcgttcat aattggggca gacctacatt atacaatgac agttataaag
      361 tctattatgg atggttatct gctactgata tagttaactg gaaagagcaa tatggagatc
      421 gaatatttga aaagaatatt cggaacttta agcaaaatac ggatgttaat aacggaataa
      481 aaataatttc tgaaaaagtt gaaaaaaatc taaaaggtgt ttcaacaacg gattatatca
      541 atttaaaatt gattggagca agtataatta atggagcgca aacaacgggt tctttatttg
      601 aagcatacca ttctgaagat attgatttga caaatgtttc agtccaagtt caaataatag
      661 tattaggaga agatattgat aatatcggac ctaaaataac taagttatcg aatactcaaa
      721 atagaataga aaataaagat tttgctgctc aggataaaga acaagaaaga ttgatgaaag
      781 atcttgcaat tgatggtaaa cagtatgtgt atcgtcaagg tgtcgagcta cctaattctg
      841 atgaaggttg tgatctggat agtgcaacag tggctctagg ttgctattta gatgatgttg
      901 caatttctac acagatgaag agagcatatg gtagcatttt tgacaatact aataaacctc
      961 catataagct aatctttaat tccggaactt ctgcatataa attatggaat tgcgttgaag
     1021 tgtatcgcga attacaaaac atagaagggg agtatcaaca agatccaaat aatcaatcta
     1081 aaaagttgat gtctattcat ggaaatagat ttattcttca tttgattttc caaaagttaa
     1141 aaaataaccc aagtttagat ttcgagaatg gatatattac aacttttcca aatttaactg
     1201 aagagtattg tttaataatg gaagaattga taagagcgaa ggaagagtta tacccagaag
     1261 cttatccagc taatatattt aaaaatggta aacgtactaa agaattaaaa gaaaaaatgt
     1321 ctttttaata agataagggg aaaaaatgct agaacgttat tcacgccctg agatggcggc
     1381 aatttggaca gaggaaaata aataccatgc ttggttggag gtcgagattt tggctgacga
     1441 ggcatgggct gagttgggtg agattcctaa ggaggatgtg gctaagattc gtgagaaggc
     1501 ggattttgac attgaccgca ttcttgaaat tgagcaggac acgcgtcacg atgtggtggc
     1561 tttcacgcgt gcggtttctg aaacgcttgg tgaggagcgc aagtgggtgc actacggttt
     1621 gacctcgact gacgtggtgg acactgccta tggttacctc tacaagcaag ctaacgacat
     1681 tatccgtcgc gatcttgaga atttcaccaa tatcgtggca gacaaggcgc gtgagcacaa
     1741 aatgaccatc atgatgggtc gtacccacgg tgttcacgcc gagccaacga ctttcggtct
     1801 taagttggcg acttggtaca gcgagatgaa acgtaatatt gagcgttttg aacatgctgc
     1861 cgcaggtgtg gaagctggta agatttcagg tgccgttggt aactttgcca acatcccacc
     1921 ttttgtggaa gaatatgtct gtgacaaatt aggcattcgt ccgcaagaaa tttcaacaca
     1981 agttcttcca cgtgaccttc acgcagaata ttttgcagtg cttgcaagta ttgcaacttc
     2041 tatcgaacgt atggcgacag agattcgagg tctgcaaaag tcagaacaac gtgaagttga
     2101 agaattcttt gccaaaggtc agaaaggtag ctctgctatg cctcacaaac gcaacccaat
     2161 cggttcagag aacatgacag ggctagcgcg cgtgattcgt ggtcacatgg tgacagctta
     2221 tgagaacgtg tcactttggc atgagcgtga catttcgcac tcatcagctg agcgtatcat
     2281 cacacctgac acaactatct tgattgacta catgctcaac cgctttggta atatcgttaa
     2341 gaacttgact gtcttcccgg aaaatatgat gcgcaatatg gaatcaactt ttggtttgat
     2401 ttatagtcaa cgtgttatgc tcaaattgat tgaaaaagga atgacacgag aagaagctta
     2461 tgacttagtt caacctaaga cagcttattc ctgggacaat caagtggatt tcaaaccact
     2521 tttagaagaa gacaccaaag ttacctcttg tcttacacaa gaagaaattg atgaactatt
     2581 taatccgatt tattacacaa aacgtgttga tgatattttt aagcgtttag ggatttaata
     2641 taaaaaaaag aagg
//
LOCUS       DAUGQX010000085         2556 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUGQX010000085 DAUGQX010000000
VERSION     DAUGQX010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2556
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.085"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            201..935
                     /gene="cofE"
                     /locus_tag="VIA51_001721"
     CDS             201..935
                     /gene="cofE"
                     /locus_tag="VIA51_001721"
                     /EC_number="6.3.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ8683643.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSEFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIRGLDYKWSENTSIKEALNE"
     gene            928..1914
                     /locus_tag="VIA51_001722"
     CDS             928..1914
                     /locus_tag="VIA51_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ8683644.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVDFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1924..>2556
                     /locus_tag="VIA51_001723"
     CDS             1924..>2556
                     /locus_tag="VIA51_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8683645.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVMVVR"
BASE COUNT          955 a          309 c          497 g          795 t
ORIGIN      
        1 tgttaacaat gatttaggaa tacattatgt agaactaggt aaaggaatta tcgattataa
       61 aacaatcatt catgaaatcc atgaacattt tatagactta atttttagtt tagaagtaca
      121 tgaaaaagaa atagacaaaa aggcagaagt agtgaggaag tcttatctga cactaaatga
      181 gtatattaat ggaggctaaa atgaatttga gtatatttgg tttaaagaat attccttatt
      241 tgaaagaagg ggatagtata gaaaagctta ttgaagaaag cattaaaact tcagaatttt
      301 ttatcgaaga caatgatgtg ctttgcatag cttctaaagt tgtatctatc gcagaaggcc
      361 aggtgatgtc tttaaacgag atacaagtga gtgatgtagc aaaagaaatc cacaggaata
      421 ttcctcgtaa agatcctaga ataattgaaa ttatgctaaa tttagtcaat agagatctgt
      481 cacgtttaga tatcaaaaaa aattacattg gttgtcgctt ggaaaatggt ttaaagttga
      541 caagtggtgg aatcgataga aaatcagtag atgaagtatt tcttttacct aataatccgg
      601 atgcttctgc aaaaagaatt tcggaatatc ttaaaaaatc acttggaaaa aatgttgcag
      661 ttgttataac agatagtgat ggtagagagg ataaaagagg tgctactcaa gtagcaattg
      721 gtatttatgg tattcatcct ttgagaaaaa cagaagtaat agattcacaa ggagagacaa
      781 taaaattcca agaagagact ttgtgtgata tgattgcagc ttgtgctggc ttagtaatgg
      841 ggcaacgtgg aactggaatt ccagctgtcc tcattagggg cttggattat aaatggtctg
      901 aaaatactag tattaaggaa gcattaaatg agtagaaatc aggactgtaa gaatattcta
      961 atcattggtt ttggaaaaat tgggaaaatt aaagcgtaca agtggctatc acgcggatat
     1021 gaggtatatg tcaaagattt gaaattctcc agcatgaaat accttaatac aaatagtgat
     1081 gtgttggatg atttatcacg acaatatttt actattgaga tttgtactcc gacaaatcac
     1141 caccttacgc tattgaaaac cgttataaca aggtatgtct attcttatat tagcattgaa
     1201 aaaccactgt gtaataggtt agaagattta gaagaaatga agtcgctagt agaaagtcac
     1261 ccacatctag caaaaaaaat ttttgccagt gaacaatact tcttttcgaa aattttggaa
     1321 aaactgttac aagtagattg tttctctcta gataaaatca aggaaataac agttgatttt
     1381 tctaaagata ggattgagga taacgagaat gggagatttt tagataaaga gatattgggc
     1441 tatggaatag agattcctca tatcattgct gtcatttctt atttaggaat ttcattagaa
     1501 gaattcaaaa aaggaatctt tgtgaatgct atttatataa aagacttaga gaaacacgat
     1561 tattcaatag aaatcttatc ttgtattaat caaacagtga ttaaaattat tagtaatttg
     1621 ggaagttttg caataagaga gggcaagatt gaaggaggtg atgctaaaac agtaagaaga
     1681 gttaccattg atgacaaaac aatactattt gatccacatc ctaaactcga gaggtataag
     1741 agtgaattgg taactgggac aaatacgttt caaatacacg atgatatgat ggacacgtat
     1801 atcagtttgt tagaaggaaa tgctattcct gaagattgct atatcaataa tgcaattgag
     1861 ataacaaaat tattaattaa cttatattca gaatgtgaaa aaatttattt atgaggtgta
     1921 actatggatt taaaaattac aaacggcttt tatgacccaa gtcatttatc atacgaagta
     1981 gtagaacgca aaggcttagg tcaccctgat accttagcag atggaattgc tgagcaaatt
     2041 gaaattgatt actcacttta ttgtttggac aagtttggtg ttattccaca tcataatttt
     2101 gataagatta ttatccgagg gggacattca gttcaggatt ttggtggaag tgactttatt
     2161 gaaccaatta aaattatttt tctaggtagg gcgagcaaaa aatgttttaa tagttcaatt
     2221 ccacttttta aaattcagaa aaaggctgca actaaatatt taaatagaat tttacctaat
     2281 ttagatgttg aaaattatgt agaatttgag acattgacct cagattttac tacaaaaact
     2341 aattggttct cgcctgaagc aatagaagat ttaccggagt atctagatgt accaaaggca
     2401 aatgatacag ctacaatgat aagttattgg ccattaacaa tttctgaaga attagcatta
     2461 atgattgaag ggtattttta taaattagat aagaatgaat taccaacgcc aagatttact
     2521 aaaatgggtg gtgatattaa agtaatggtc gtaagg
//
LOCUS       DAUGQX010000086         2093 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUGQX010000086 DAUGQX010000000
VERSION     DAUGQX010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2093
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.086"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            79..2070
                     /gene="uvrB"
                     /locus_tag="VIA51_001724"
     CDS             79..2070
                     /gene="uvrB"
                     /locus_tag="VIA51_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEQ8683646.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
BASE COUNT          695 a          353 c          458 g          587 t
ORIGIN      
        1 ttacgcttat tggaggtgat tctggcttat ctatgttaaa atagtctata agagagtaag
       61 actattagag ggtataaaat gattgataaa cgtgatgata aaccatttaa actaaaatca
      121 aagtataaac cgtctggtga tcagccacaa gctattgaaa gcctagttga taatatcgag
      181 ggcggagaaa aagctcagat tctcctaggt gctacaggaa cgggaaaaac atacaccatg
      241 agccaagtaa ttagtaaagt aaataaacct accttagtga tagctcacaa taaaacctta
      301 gcaggacaat tatatggtga atttaaagaa ttttttccag acaatgctgt ggaatatttt
      361 gtttcctatt atgattacta ccaacctgaa gcatatgtcc catcaagcga cacctatatc
      421 gaaaaagata gttcagtcaa tgatgaaatc gataaacttc gccattcagc cacctcttct
      481 ttacttgagc gtaacgatgt catagtggta gcttctgtat cttgtattta tggactaggt
      541 tcgccaaaag agtacgcaga ttcagcagtc agcctacgtc caggtcagga gatatcacgt
      601 gacactttgc taaatcaatt agtagatatt caatttgagc gtaatgatat tgattttcaa
      661 cgcggctgtt ttcgtgtacg tggcgatgtt gttgaggtct ttccagcatc cagggatgaa
      721 catgcttttc gggtggaatt tttcggggat gagattgacc gtatatgtga aatcgaaagt
      781 ttaactggta aaactattgg agaagttgac catttggttt tatttccagc tactcacttt
      841 gtaacaaatg atgagcatat ggagcaatca atagccaaaa ttcaagcaga gttagcagag
      901 cagttacagt tatttgaatc tgaaggtaaa ctactagaag cacagcgatt acgccaaaga
      961 acggaatatg atattgaaat gttacgtgaa atgggctata ctagcggagt cgaaaactat
     1021 tcccgtcata tggatggcag gtcaccagga gaacctcctt ataccttgtt agatttcttc
     1081 ccagaagatt ttttaattat gattgatgaa agtcacatga caatgggaca aatcaaaggc
     1141 atgtataatg gtgaccaagc cagaaaacaa atgctagttg actatggttt tcgattgcca
     1201 tcagctcttg ataatcgtcc cttaagacgc gaggaatttg aaagtcatgt gcaccaaatt
     1261 gtctatgttt cagcaacgcc tggtgaatac gaaatgtcac agactaatac aattattgag
     1321 caaattattc gtccgactgg gctacttgat cctgaaattg atgtaaggtc aagtatgggg
     1381 caaatggatg atttgttggg agaaattaac cagcgcgtag cgcgcgatga acggacgttc
     1441 atcacaacct taactaaaaa aatggcagaa gatttgactg attatctaaa agagatgggt
     1501 gtcaaggtca agtatatgca cagtgatatt aaaaccttag agcgaacaga aattattcgt
     1561 gatttacgac ttggtgtttt tgatgtcttg attggaatca atctgctccg tgaagggatt
     1621 gatgtgccag aagttagtct tgtagccatt ttggatgctg ataaagaggg tttcctccgt
     1681 aatgaacgcg gcttgattca gaccatcggt agagcagctc gaaacgtaga tggtcatgtc
     1741 attatgtatg cggacaagat gacagattct atgcagcgag ctattgacga aacggctcgt
     1801 cgtcgtgaga ttcaaatagc atataacaaa gcgcacggca tcgttccaca aactataaaa
     1861 aaagacatca gaggccttat tagtataagt aaaacaagcc acaatgatat atcaaaagaa
     1921 gagatggatt atgaaagtat gtcaagagga gaacgaaaag aagcgatcaa tgctctgcaa
     1981 aaacaaatgc aagaggcagc tgaattactt gatttcgaat tggcagctca aatgcgagac
     2041 ttgattttag aacttaaatt aatggactag gttttgaata aagcttatat tat
//
LOCUS       DAUGQX010000087         1938 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUGQX010000087 DAUGQX010000000
VERSION     DAUGQX010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1938
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.087"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            143..784
                     /locus_tag="VIA51_001725"
     CDS             143..784
                     /locus_tag="VIA51_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEQ8683647.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEVTPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPSDIEKSKGR"
     gene            complement(831..1673)
                     /locus_tag="VIA51_001726"
     CDS             complement(831..1673)
                     /locus_tag="VIA51_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEQ8683648.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVSVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKADWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAFVLFALGIWLGLWMSQLE
                     EKYK"
BASE COUNT          709 a          330 c          361 g          538 t
ORIGIN      
        1 gttttttgat atgtcaatat tttatatata aaaaaataac atatatatca aaaatcacta
       61 actaggagta ataagttgac caaaaagcta ggattggtta tgatgaagat aagattaacg
      121 gaaagagaaa ttagggaaga ctatgaagga cttattaaaa cagtatcagg caaaaccact
      181 aggagaggag aagcggtacg ccgtattttt acctcttatt cttgtcaatg atgactggca
      241 tgtcttatat gaagtcagaa gtcagcatat ttcacaaccg ggggaagttt ctttcccagg
      301 gggacaagta gaaaatcagg agacacttca agaagctgct atccgagaaa cagttgagga
      361 attgactgtt gatgcgtccc agatccagct atggggtgaa attgattatt tagtacagtc
      421 ttctagaact attcattgtt tcgttggtca attagtcgtt gatgactgga aaagcataca
      481 gcctaacgaa gaagttgaca aggtctttat agtaccttta cgtcagctac ttttcactga
      541 tcctgtctat tatcgtttag aagtcactcc tattgagaca acggattttc cttttgaccg
      601 tattcgtaat gggaaatact accaatttag tcaagagtac cgtagtattc cgttttatga
      661 aaatctagaa gaaaccatat ggggaatgac tgcccagttt actaagtgtt taaccgatat
      721 tctaaatgat gaatcaattg caaagaaaaa cccctcagat attgaaaaat ctaaggggag
      781 atagagcact agtttgttgg cgtcaacttt ttgtcaacaa actgtaaagg ttatttgtat
      841 ttttcttcta attgactcat ccaaagtccg agccaaatac caagagcaaa taacacaaag
      901 gccataagcc aggttaagat acctgcatga ctgtaggaaa tggattcggg actactacta
      961 tttggaataa gaattaatag cgtgctggat aatacaatac caatgataaa gtggtaaact
     1021 tttgaatgat ggtgctgtaa agcataatcc atacttttag aaaaagccaa gatggctagg
     1081 actcctccga tagcaatagg taagaaagtc cctaataaat ccaaagattt gaaccctatt
     1141 aacataggac catagagtcc taagataagt aagagatttg acgggcttag tccagggacc
     1201 agtactccta aagcaattaa ggcacctgct aaaataaagg ttaaaaagtt agctggtaag
     1261 gtaccgatta agtcatttaa gaagtaaaga cctagtcctg aaataacaaa ggtaaggact
     1321 agccatagcc agtcagcttt gtctctttga gactgcttgg ttgactcctt aatcagacta
     1381 ggaatagtgc cgacaatagc gccagcaaat ccccataaga cgctaacttg atagtgctta
     1441 agcaaaaact caacggggaa agaaaagaga gcaataccta aaataccacc aattcctact
     1501 ggtaagaaaa ataagacatt ttcaataaag ttatccctca tatgagctaa aaaggaaatc
     1561 attcgctcat agattcctaa aatggctgcg agaacaccac cggatacacc aggtaaaata
     1621 aaacctagtg caataatcat gcctttaaaa actcttgaaa taaatgaaac cattgttgcc
     1681 tcctgaaaag aatgatttta ttgtatcata aatttaaaga attgctgaca caaagctgca
     1741 tatccctact aaaataattg ttcctaataa ataatacatt caattttgaa gatattttcc
     1801 ttaaacacca tgtctttgtg atcaagtcaa gtttgattgt caaagttgta aataaaattt
     1861 acaaagactg taaaccttac gataattatt aaaaagataa acgaaaaaaa gcttaggtca
     1921 aagacttttg atagtaaa
//
LOCUS       DAUGQX010000088         1860 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUGQX010000088 DAUGQX010000000
VERSION     DAUGQX010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.088"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            15..353
                     /locus_tag="VIA51_001727"
     CDS             15..353
                     /locus_tag="VIA51_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEQ8683649.1"
                     /translation="MKPPFTVTNTMLNKVVEISKIIGNLELQVQKDLKLRKENRIQSI
                     HSSLAIEQNSLTVEQITAIIDGKRVLGNPREIREVKNAYEAYEEILTLTPYDESHFFK
                     MKKFQQYIYR"
     gene            377..1201
                     /locus_tag="VIA51_001728"
     CDS             377..1201
                     /locus_tag="VIA51_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine ligase"
                     /protein_id="HEQ8683650.1"
                     /translation="MGLGSDSLPVKISLFDVDTYLADSMQFHLEYILRLFPKSGVHYL
                     MPTFRGEAVDHRHLSQFYHSECEIEGDLHYVMNLVDRYIKFLVSEILRECRDSIFAIT
                     KDVSHLESFIDRKIPIITFEEACTILENEIDSLEYNDEHHFYVLTDVGEKKLMEHFEG
                     VVWVKNYPCKSVPFYQRFSTDHLFAYNADLLLGIGETVGCGERCETYEEVVENMNYLQ
                     VDASEYSWYLEMKKTRPMKSSGFGLGVERLIAWILKCDDVRKVQLISRENGIDYLP"
     gene            1215..>1860
                     /locus_tag="VIA51_001729"
     CDS             1215..>1860
                     /locus_tag="VIA51_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEQ8683651.1"
                     /translation="MKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFV
                     ETIETSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSF
                     RFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNF
                     SELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRN"
BASE COUNT          679 a          216 c          372 g          593 t
ORIGIN      
        1 gtaaggagaa aatgatgaaa ccacctttta cagttacgaa taccatgtta aataaggtag
       61 tagagatttc taaaattatt ggtaatttag aattacaagt acagaaagat ttaaaattaa
      121 gaaaagaaaa tcgtattcag tctattcact catcactcgc tattgaacaa aattctttaa
      181 cagtagaaca aataacagcc attattgatg ggaaaagagt gttagggaac ccccgtgaga
      241 taagagaagt aaaaaacgct tatgaagctt atgaagaaat tttaacgcta actccctatg
      301 atgaatcaca tttttttaaa atgaagaaat ttcaacagta catttaccga taacaacatc
      361 gtcaatcaca agtcctatgg ggttggggag tgattcgcta cctgtaaaaa tttccttatt
      421 tgatgttgat acctatcttg cagattcgat gcagtttcac ttagagtata tacttagact
      481 ttttccaaag tcaggagttc attacttaat gcctactttt agaggagaag cagtagatca
      541 tcgacattta tcgcaatttt atcatagtga gtgtgagata gagggagatt tacactatgt
      601 gatgaattta gtggatagat atattaagtt tctggttagt gaaattctta gagagtgtcg
      661 agatagtatt tttgctataa caaaagatgt aagtcatttg gaaagtttta ttgatcgaaa
      721 gataccaatt attacgtttg aagaggcttg tactatattg gaaaatgaaa tagattcatt
      781 ggaatataat gatgaacatc atttttatgt gttaacagat gttggggaaa agaaattaat
      841 ggaacatttt gagggagtag tttgggtaaa aaattatccc tgtaaaagtg tcccttttta
      901 tcaaaggttc tcaacagatc atctatttgc ctataatgca gatttgttgt taggaatagg
      961 cgaaactgta ggttgtggag aaagatgcga aacatatgaa gaagttgtag aaaatatgaa
     1021 ttatttacaa gtagatgctt ctgaatatag ttggtattta gaaatgaaaa aaacaagacc
     1081 tatgaaatct tcaggatttg gtttaggagt agagcgttta atagcgtgga tattgaagtg
     1141 cgatgatgtt cgaaaagttc aattaatcag tagagaaaat gggattgatt atttaccata
     1201 aaggaggaag aaaaatgaaa aagaatattt taattgtagg tggaggtcca gagataacta
     1261 tatgttatga tttaattaac aatagtacgg agtataattt cttttcagta tcagaaattc
     1321 ctacgatgta tccagagttg tttgtagaaa caattgaaac cagctttaga aattttggaa
     1381 agacgattga acaaattaaa gagctcaaat attctattga tgctgttgct tgttgggatg
     1441 aagctttaac gcatatagct gatgatattt caaaagaatt aggattgaac cctatttcat
     1501 cgctagattc tcaatcattc aggtttaaag atcgaatgag aatggtatgt gaagctggtg
     1561 gactaaaaat gcccaaatat aaaattatca atcaattttc agatacaaat aaaataatca
     1621 attggaaata tccattaata gtgaaaccaa cctctttttt agcaagtata ggagtgaaaa
     1681 aagtttataa tttttcagaa ttacaacaag cagtttctca aatgcttaat gtaaaatttc
     1741 cggtttacat agcttcaggg gtatatgaat tgggggaatt atataattta gaacctagag
     1801 ttttggtgga agagtttatt gatggagaag aatatagctt agagagcgtg gtaagaaatg
//
LOCUS       DAUGQX010000089         1787 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUGQX010000089 DAUGQX010000000
VERSION     DAUGQX010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1787
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.089"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..274
                     /locus_tag="VIA51_001730"
     CDS             <1..274
                     /locus_tag="VIA51_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="biotin carboxylase"
                     /protein_id="HEQ8683652.1"
                     /translation="ELNTDTNKFSGIVFFRLNPENYGKIFNGVSYDAPKTSLIFEEKI
                     YKKEGTVLPNPINWSNERVGYVCLENKEYAVLEKEMKEILKSLSIE"
     gene            199..1218
                     /locus_tag="VIA51_001731"
     CDS             199..1218
                     /locus_tag="VIA51_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEQ8683653.1"
                     /translation="MFGKQGIRCARKGDERNIKIIVNRVNSERNIKSIGICSPSYPGT
                     FHYQKRYKRGVEFLQNKGFTIVEGNLTGKEGYRGEISGGVQDRAEELNQLIPRVDVIM
                     TSIGGYNSNSVLKYIDYDLFKQKSPIFIGYSDTTALALALYKKTGCITYLSQSVISNF
                     GEFEPFNELNYFYFDFMLQSKCETLMVQIPDVWTDEWINWETYERTKKTNKNEWIIFN
                     KGEFNGTLIGGNLDTIVGIIGTEYMPKITEDTILLLEDVYTDLGRLYRNFTTLALHGI
                     FDKIGGLIISKFETIGENSDVINDIINEFVGHRKIPILLNFDCGHTHPSCLMPIGGKI
                     TLSLS"
     gene            1231..1431
                     /locus_tag="VIA51_001732"
     CDS             1231..1431
                     /locus_tag="VIA51_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683654.1"
                     /translation="MNNRESKLTGFYDVFEEEVEKINHIHNVFVEESEKFGFQQMKIA
                     MVEHRKKYLDATDVHYTKYKNI"
     gene            1551..>1787
                     /locus_tag="VIA51_001733"
     CDS             1551..>1787
                     /locus_tag="VIA51_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683655.1"
                     /translation="MLFRDRIPTYKGYRRQFNQILLGAWGIESAYVDAEIIVATWRGL
                     QRFKGIKVEFIQLSNKNIFDVLEKDLSKKLRFEDI"
BASE COUNT          676 a          216 c          353 g          542 t
ORIGIN      
        1 agagttaaat acagacacta ataagttttc aggaattgta tttttcagac tcaatccaga
       61 gaattacgga aaaatattta atggagtgag ttacgatgca cctaaaactt cactaatatt
      121 tgaagaaaag atatataaaa aggaaggaac tgtattgcca aatccgatta attggagtaa
      181 tgagagagta ggatatgtct gtttggaaaa caaggaatac gctgtgctag aaaaggagat
      241 gaaagaaata ttaaaatcat tgtcaataga gtaaatagtg aaagaaacat caaatctata
      301 ggtatttgtt caccctccta tccggggaca tttcattatc agaaacgata taagagagga
      361 gtagaatttt tacaaaataa aggatttact atagtagagg gaaatttaac aggaaaagaa
      421 ggttatagag gggaaatttc aggaggagtt caagacagag ctgaagaatt aaatcaactt
      481 attccgcgtg tggatgtcat catgacttcc ataggtggct acaattctaa ttctgtatta
      541 aagtatatag actacgatct atttaaacag aaatctccta tctttattgg atattctgac
      601 acaacagctc ttgctttagc cttatataaa aagactggat gtataactta cctgtctcag
      661 agcgttatct ctaattttgg agagtttgaa ccgtttaatg aattaaatta tttctatttt
      721 gacttcatgc ttcagagtaa gtgcgaaacc ttaatggtac aaataccaga tgtttggacg
      781 gatgagtgga taaattggga aacctatgaa agaaccaaaa aaacaaataa aaatgagtgg
      841 attattttta acaaaggtga atttaatggt actttgatcg gaggaaatct cgataccatt
      901 gtaggaataa taggaactga gtatatgcca aaaataacag aggataccat actcttgtta
      961 gaagatgtat atacggatct aggaagacta tataggaatt tcacaacgct tgccttacat
     1021 ggtatttttg ataaaatagg aggacttatt atttcaaaat ttgaaacaat aggggaaaat
     1081 agcgatgtta ttaatgatat cattaatgaa tttgtagggc atagaaagat tcctatttta
     1141 ttgaattttg attgtggtca tacccatcct agctgtttaa tgcctattgg tggtaaaatt
     1201 acgttgagtt taagctaaaa gaggtggtat atgaacaata gagaaagtaa attaacgggt
     1261 ttctatgatg tttttgagga agaagtagaa aaaataaatc atattcataa tgtttttgta
     1321 gaggagtcag aaaaatttgg ctttcaacag atgaagattg ctatggtaga gcatagaaaa
     1381 aaatacttag atgcaaccga tgttcattat acaaaataca aaaatatttg aagttcatag
     1441 agtaaaagaa gagtcagtat acgccctcca atcagatttg gcacttagta tgtcgccgtt
     1501 gtatagctaa cttaccacaa caaatacctg taaagtggat tcaagacaga gtgttattta
     1561 gagatagaat tcctacatat aaaggttata gaagacaatt taatcaaata ttattaggtg
     1621 catggggaat agaatcagct tatgtggatg cagaaataat agttgcaact tggcgaggct
     1681 tgcaacgatt taaaggaatt aaagtagaat ttattcaact gtctaacaaa aatatatttg
     1741 atgttttgga gaaagattta tctaaaaagt taagatttga agatatt
//
LOCUS       DAUGQX010000090         1682 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUGQX010000090 DAUGQX010000000
VERSION     DAUGQX010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1682
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.090"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            105..1025
                     /locus_tag="VIA51_001734"
     CDS             105..1025
                     /locus_tag="VIA51_001734"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEQ8683656.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1079..1327
                     /locus_tag="VIA51_001735"
     CDS             1079..1327
                     /locus_tag="VIA51_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEQ8683657.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(1452..>1682)
                     /locus_tag="VIA51_001736"
     CDS             complement(1452..>1682)
                     /locus_tag="VIA51_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8683658.1"
                     /translation="TDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTGGFGL
                     GLALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
BASE COUNT          590 a          308 c          240 g          544 t
ORIGIN      
        1 tttgagttaa ttgtattaat tttcgtgtaa atactaacga aaaattattt attttttaac
       61 taaaatggta taatgtaagc actgtcaaat gattaggagc taccatgtca aatgaattta
      121 ttaactttga aaaaatttct agagagtctt ggaaaacatt acatcaaaag gcaaaagctc
      181 tcctcacaca agaggaactt aaaagtatta ctagcttaaa tgataacatc agtattaacg
      241 atgtcattga tatctacctt ccattaatta atctgatcca ggtttacaaa attgcgcaag
      301 aaaatctttc tttttctaaa agcctttttc taaaaaaaga cattcaatta aggcctttta
      361 ttattggaat ttctggttca gtagctgttg gtaaatcaac aactagtcgt cttttacaac
      421 ttttattatc acgaacgcac cccaatagtc aagtcgaact ggtaacgact gatggttttt
      481 tatatcctaa tcagtttctt attgaacaag gactgttaaa tcgtaaagga tttccagaat
      541 cttataacat ggaacttctc ttagattttc tagattccat caaaaatggt caaactgctt
      601 ttgcacccgt ctattctcat gatatttacg atattatccc aaatcaaaaa caatcattta
      661 ataaccctga cttccttatc gtcgaaggta ttaacgtttt tcaaaatcaa caaaacaatc
      721 gtttatatat gagtgattac tttgattttt ctatttatat tgatgcagac agcagtcaca
      781 tcgaaacctg gtacattgaa cggtttctaa gcattttaaa attagcaaaa cgtgaccctc
      841 ataattatta tgcccaatat gcacaattac ctcgatctga ggctatagca tttgcgcgca
      901 acgtttggaa aaccgttaat ttagaaaatc ttgaaaaatt cattgaacct acacgtaacc
      961 gtgctgaatt aattttacat aaaagtgctg atcataaaat tgatgaaatt tacctcaaaa
     1021 agtgataaag ggttgccaaa cgcatatatt ttctatataa taatgtagtt agattaattt
     1081 ggaggtgaaa acattggcaa atattaaatc agctattaaa cgcgctgaac ttaacgttaa
     1141 agcaaacgaa aaaaactcag cacaaaaatc agctatgcgt actgctatca aagcatttga
     1201 agctaaccca tctgaagagc ttttccgcgc tgcttcttca agcatcgata aagctgaatc
     1261 aaaaggtttg attcacaaaa acaaagcaag ccgcgataaa gcacgccttg ctgcaaaact
     1321 tggctaataa atatccaatg aaaactccag ctggagtttt tttatacggt aaaaactcaa
     1381 aaaatacaat aaagcgttga cagttaaaaa taactttaaa agggctgacc ttattggtcg
     1441 ccctttttag cttatagttt gacttcaaaa atactacctt taggatcatt atcctttact
     1501 gtaatatttc cttttaaaga catcacgatt tgctgagcta aagccaaccc caagccaaat
     1561 ccacctgttt gccgtgttct agctttgtca actcgataaa aacgatcaaa aatctttttc
     1621 ttttcttcat ctgttatccc tggaccatta tcaataacag aaattaataa atttttgtcc
     1681 gt
//
LOCUS       DAUGQX010000091         1526 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUGQX010000091 DAUGQX010000000
VERSION     DAUGQX010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1526
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.091"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            202..813
                     /gene="rpsD"
                     /locus_tag="VIA51_001737"
     CDS             202..813
                     /gene="rpsD"
                     /locus_tag="VIA51_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEQ8683659.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(967..1500)
                     /locus_tag="VIA51_001738"
     CDS             complement(967..1500)
                     /locus_tag="VIA51_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8683660.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
BASE COUNT          462 a          282 c          269 g          513 t
ORIGIN      
        1 atgatagata gactgacttt acaaaacaac tttcttatgg taaactgttc tttgtgcgaa
       61 ataacagcag aaaaatatga agctcgtcaa caggtggtta tctattcaag taacctttgc
      121 tgtttaggcg aaaaccccct gcacgaatca ggatttttta aaccgttatt tcctcaaaaa
      181 atttagagga ggacatgtaa tatgtcacgt tatactggtc catcatggaa acaatcacgt
      241 cgccttggtt tatcacttac aggcacaggt aaagaattgg cacgtcgtaa ctacgttcct
      301 ggtcaacacg gtccaaacaa ccgtagcaaa ctctcagaat atggtttgca gttagctgag
      361 aaacaaaaac ttcgtttctc atacggttta ggtgaaaaac aattccgtaa cttgttcgtt
      421 caagctacaa aaatcaaaga aggaactctt ggtttcaact ttatggttct tttagaacgt
      481 cgtcttgaca acgttgttta ccgtctaggt ttagcaacta ctcgtcgtca agcacgtcaa
      541 ttcgttaacc acggtcacat ccttgttgac ggtaaacgcg ttgatatccc ttcataccgc
      601 gttgatccag gtcaagtgat ttcagttcgc gaaaaatcaa tgaaagtacc tgcaatcctt
      661 gaagctgttg aagctactct tggacgtcca gctttcgtat catttgatgc tgaaaaactt
      721 gaaggttcat tgactcgcct tccagaacgc gatgaaatta acccagaaat caatgaagca
      781 cttgtcgttg aattctataa caaaatgctt taattttaag attaaactta caaaaagcct
      841 atttaatagg ctttttttgt atctcataac aaatttatcc tgatcccttc attttactat
      901 ggcttctaaa aaagttatca ctaaggctga tgacttgtaa aatgatactt tcgtaagggt
      961 tattatttag gtactcgtaa gcattttgag aacgaattgt gtcatttctt gaggtgattc
     1021 ttttttacct ttagcaatcc aactttgaca gacaccaaaa aaagcatggg ctaagtagat
     1081 actttggtat tctttttccg tttgagataa ctcttcggta ctgaacttgt cctgtaaatc
     1141 agtagtgatg agtaggcgaa ctttattgat gataaaggcc tgtatttctt tagtaccgtt
     1201 agcagacaaa agggaagaga gaagctgttc tctttggaga aattcaaata cttcaaggaa
     1261 ggcttgttct ttattttgat attttttctc aaaaatatat tctaatttgt gaaaaaaggt
     1321 ttgctgataa tagtcaatca tttcatattt atctttatag tgtgtgtaaa aactagagcg
     1381 actaattcca gctcttttag ataatttaac tgtggtaata tcgtcaaaac tttcggtttt
     1441 tagtaacata accattgctt ttaaaattgc ttgcttcgta ttttctttac ggttgaccat
     1501 ctaccatctc tccttttgaa cacttt
//
LOCUS       DAUGQX010000092         1470 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUGQX010000092 DAUGQX010000000
VERSION     DAUGQX010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.092"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            147..1217
                     /gene="xerS"
                     /locus_tag="VIA51_001739"
     CDS             147..1217
                     /gene="xerS"
                     /locus_tag="VIA51_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEQ8683661.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT          472 a          240 c          280 g          478 t
ORIGIN      
        1 tctttccgaa aaactgtaat tttcttgaaa aatatttata ggtgtgatat actgctcttg
       61 tagagaatga atgtcataaa atacatgaga caatttacga aaattcattt ttgaaaaaat
      121 tgttattgtt aaggaattat gatgatatga gacgcgaatt attactagaa aaaattgaaa
      181 cctacaaggc tatcatgccc tggtatgttt tagattatta ccaatccaaa ttagctgttc
      241 catacagctt taccacctta tatgagtatt taaaagaata caaacgcttt tttgattggc
      301 tgatggatgc tgatttaacg caggcgccaa agattgctga tattgacttg agcacgcttg
      361 agcaccttac caagaaggat ttagaggcct ttgtgcttta tttgcgggaa cgaccttctc
      421 tcaacaccta ttccaccaaa gaggggcttt ctcaaaccac tattaatcgg accttgtctg
      481 ccttatcaag cctttacaag tacttgactg aagaggttga aaatgaccaa ggggagcctt
      541 atttttatcg gaatgttatg aaaaaagtgt caacaaaaaa gaaaaaagaa accctggctt
      601 ccagagcgga aaatattaag cagaaactgt ttttaggtga tgaaactcta gctttcttgg
      661 attatgtgga taaggaatat gagcaaaaat tgtctaatcg tgccaaatct tctttccgta
      721 aaaataagga gagggatttg gctattattg ctctactact tgcttctggt gttcgtttgt
      781 ctgaagcagt gaatcttgat ttaaaagatg tcaatctaaa tatgatgatt atcgaagtta
      841 ttcgcaaagg cggaaaacgt gattcagtca atgtagcagg ttttgcgaaa ggttatttgg
      901 agtcttattt agctgttcgt cagagacgtt acaaggctga aaaacaggat cttgctttct
      961 ttttaacaga ataccgtggc gttccaaatc gaatggatgc ttctagtata gaaaagatgg
     1021 ttggcaagta ctctgaggat tttaaaattc gtgtgactcc tcacaaattg cgtcatacgc
     1081 tagcgacaag actatatgat gctactaaat ctcaggtgtt agttagtcat caattaggcc
     1141 attcctctac tcaagtcacg gatctttata cccatattgt caatgatgag caaaaaaatg
     1201 ctttagataa cctttaatgt tacataattg tttttatgta acattaaaga taaaaatagc
     1261 ttcaaaatta actttaatag atggctacta ttaaccgtga cagtttggtg tcaggccgtt
     1321 ttccaaacta ctcaagccac ttagaaaaag gaatattact gctaactttg tcccttcttt
     1381 gaatgacttt tttgtgatgt ttatagatta aatctagtag ggttctcatc aaaaagatga
     1441 gataagcctg tttttagtat gtcagtactt
//
LOCUS       DAUGQX010000093         1412 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUGQX010000093 DAUGQX010000000
VERSION     DAUGQX010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1412
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.093"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            217..1338
                     /gene="mnmA"
                     /locus_tag="VIA51_001740"
     CDS             217..1338
                     /gene="mnmA"
                     /locus_tag="VIA51_001740"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEQ8683662.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADKIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          438 a          232 c          310 g          432 t
ORIGIN      
        1 ttataataaa aaattattga gcaataaaat gattggcatt ccacgcagta attgttataa
       61 taaggtttgc gctgatggcg cttcaaaatc gaccttcaaa tcgacttttg aaaacgacga
      121 ccttcaatcg tacgttaact gataagaaaa agaatcataa tattcataat atgatgatta
      181 tctttttcta tcttattatt gatgggagaa ttttttatga cagataactc aaagatacgt
      241 gttgtcgttg gtatgagtgg tggcgttgat tcatctgtaa cagctctact tttaaaggag
      301 caaggttatg atgttattgg tgtcttcatg aaaaactggg acgatacaga tgaatttggt
      361 gtttgcacag ctactgaaga ttacaaagat gtagcagccg ttgctgataa aatcggtatt
      421 ccttactatt cagtcaattt tgaaaaagaa tattgggaca gagtatttga atatttcttg
      481 gccgaatacc gagcaggtcg tactccaaat cctgatgtca tgtgtaataa ggaaataaaa
      541 tttaaagctt tccttgacta tgccatgact ttaggtgcag attatgtagc aacgggacac
      601 tatgctcaag tcaagcgtga tgaaaatggt acggttcaca tgttacgtgg agctgataat
      661 ggcaaagacc aaacctactt tttaagtcaa ctatcacagg aacaactaca aaagacttta
      721 ttcccccttg gtcatttgca aaagtcagaa gttagagaaa tcgctgagcg agcagggctt
      781 gcaacggcta aaaagaaaga ttcaacaggt atttgtttta ttggtgaaaa gaatttcaaa
      841 cagtttttga gccagtactt accggcacaa aaaggtcgca tgatgactat tgatggtcgc
      901 gatatgggag aacatgccgg ccttatgtat tatactattg gtcagcgtgg gggtctgggc
      961 attggtggtc agcatggtgg ggataatcaa ccttggtttg ttgtcggtaa agatttgtcg
     1021 caaaatattt tatacgttgg tcaaggtttc taccatgaag ccctaatgtc aaatagtctt
     1081 gacgcctcag tcatccattt tacacgtgag atgccagaag agttcacatt tgaatgtact
     1141 gctaaatttc gctatcgtca acccgattca cacgtggcgg tgcatgttcg aggagataag
     1201 gcagaagttg tttttgcaga gccacagcgc gcgattactc ctggtcaagc tgttgttttc
     1261 tatgacggaa aagaatgcct tggtggtggt atgattgaca tggcttataa aaatgggcag
     1321 ccttgtcagt acatttaatg aatcttttat taagataaaa agaaagggac attcaacaat
     1381 tcctttgaca tcatatgata ttatttataa aa
//
LOCUS       DAUGQX010000094         1330 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUGQX010000094 DAUGQX010000000
VERSION     DAUGQX010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1330
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.094"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..548)
                     /locus_tag="VIA51_001741"
     CDS             complement(<1..548)
                     /locus_tag="VIA51_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEQ8683663.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIALFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPIS"
     gene            640..987
                     /gene="ssrA"
                     /locus_tag="VIA51_001742"
     tmRNA           640..987
                     /gene="ssrA"
                     /locus_tag="VIA51_001742"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1139..1327)
                     /locus_tag="VIA51_001743"
     CDS             complement(1139..1327)
                     /locus_tag="VIA51_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8683664.1"
                     /translation="MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDE
                     VVTVERVEEVMVELDYIK"
BASE COUNT          440 a          256 c          204 g          430 t
ORIGIN      
        1 gaaattggtt tagttattaa aagaatagtt acaaagcgct ttaaagacat gtccgtcaat
       61 cccgtaatca taaccataat atcagctgga gaaacaggcg atgccataca aaaaataaat
      121 aatttttcat atcctggtgt ctccaaacgc ctttcatact tgtaaaatgt tttgtcattt
      181 acaaagagta agataaattt acgaccataa gtcttaacga gcaagaagag ggctatactg
      241 ccaataatga tgcctacata attataaata aaacctgtta cagggccaaa gattaaaaaa
      301 cctgcaactg tcgtaaggcc tccaggaatc acaggaaaaa caatctgtat gatctgcacg
      361 acaataaaaa caaacggccc ccataatcta tagcgctgca ctaagtcttt aagagcatta
      421 ctatcgttta atatacctag tctatacagc caaaaagcga ggaaaaaagt accaattagt
      481 gcaataattc ctaaaatttt gataattttt tgccataata tataggcttt tgaattacgt
      541 tttgtcatag actaatcata ccataagctg taaaattttg ctatttaaaa aaagttttga
      601 tagaatagtt agtgtaagaa attggttaat tatctatttg gggttgttac ggattcgaca
      661 ggcattatga ggcatgtttt gcgtcccatc ggcagatgta aattgccagt taaatataac
      721 tgcaaaaaat acaaactctt acgctttagc tgcctaaaaa ccagctagcg tgacttctac
      781 aagattgctt gtgtcctgtt agaagtctca aaatagcaag ctacggttac gaaattgtct
      841 agtttcgtga caagagattg atagactcgc aaactaatgg cttgagttat gtgtctttag
      901 tttgttaaat gaagacataa cctatggacg tagacaaata tgttggcagg tgtttggacg
      961 tgggttcgac tcccaccagc tccatcaatg cttaccgtaa gtaatcataa cttactaaaa
     1021 ccttgttaca tcaaggtttt ttctttttgt cttgttcatg agttaccata actttctata
     1081 ttattgacaa ctaaattgac aactcttcaa ttatttttct gtctactcaa agttttcttc
     1141 atttgatata gtctaattcc accatcactt cttccactct ctctaccgtc acaacttcat
     1201 catctctcac tttttcgtgt ggtaacacat aatcaaatat ctttccgttt ttacgcacta
     1261 tcgctactgt gtcacctaaa atatacccct tatcaatcgc ttctttaaac tcatctatat
     1321 ataacatatt
//
LOCUS       DAUGQX010000095         1318 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUGQX010000095 DAUGQX010000000
VERSION     DAUGQX010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.095"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            34..651
                     /locus_tag="VIA51_001744"
     CDS             34..651
                     /locus_tag="VIA51_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8683665.1"
                     /translation="MIKAQLKNLIKTIHLVKEAGFSLNGSLYMELLHDFTHDELVHNP
                     IIESTVDTIQSVEFERVSFSYNGKDNVINDISFSIKAGERLAIVGGNGSGKSTIFKLA
                     CGLYDNYEGNIYINGINLCSIQKKSYYKRISALFQDFLKYELTLRENVGLGELSKLYS
                     DESYNTSFFTTSWDSENELRLEDIYIRYSDGKFHFTTIDESIKRD"
     gene            733..>1318
                     /locus_tag="VIA51_001745"
     CDS             733..>1318
                     /locus_tag="VIA51_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8683666.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFI"
BASE COUNT          474 a          164 c          255 g          425 t
ORIGIN      
        1 ttgctccttt attagtagat aaggaagtta tacatgatta aagctcagct aaagaatcta
       61 ataaaaacaa ttcatctcgt aaaagaggct ggtttctccc taaatggttc attgtacatg
      121 gagttattgc atgattttac gcatgatgag ttagtacata accctataat cgaaagtacg
      181 gttgatacaa ttcagtcagt tgaatttgaa agggtttctt tttcatataa tggtaaggat
      241 aatgtaataa acgatataag tttttcaatt aaagcaggag agaggttagc aattgttggt
      301 ggaaatggtt ctggaaaaag tacgattttc aaattagcct gcggtcttta cgataattat
      361 gaaggcaata tatatataaa tggtattaat ctttgttcaa tacagaaaaa gtcatactac
      421 aagagaatat ccgcattgtt ccaagatttt ttaaagtatg aattgacact gcgtgaaaat
      481 gttggattgg gtgaattatc aaagttatat agtgatgagt cttataatac ttcatttttt
      541 accacatcat gggattcaga gaatgaactg cgattggagg atatttatat aagatatagt
      601 gatggtaagt ttcattttac aactatcgat gaatcgatta aacgggattg atagagagtt
      661 tgaagagaaa gtgtattgtt ttgcttacta tacactaaac gctcagcaat atatagaatg
      721 ggagtaacta atatgttgaa aatacaaaat ctaaaaaaat cttatggtaa gagaaccata
      781 ttgaataatg tcaatatgaa tattcctaag ggaaaagtgt atgctttaat cggtccaaat
      841 ggtgctggaa aatcaactat tatgaaaatt ttgacaggct tagttagtaa gacaagtggt
      901 tctattattt ttgaaggtag agaatggtca cgtcgggatc tgcgaaaaat cgggagtatt
      961 attgaagaac caccacttta taaaaatttg agtgcttacg ataatatgaa ggtagttaca
     1021 acaatgcttg gtgtttcaga aagcactata cttccattat taaataaagt tggtctagga
     1081 aatattgaca agagaccagt aaaacaattt tctcttggaa tgaagcaacg gttaggtata
     1141 gctatctctt taataaattc acctaaacta cttatattag acgaacctac taatggcttg
     1201 gacccaattg gaattcaaga attaagggaa attatagagt catttaaatc agaaggaatg
     1261 acaattatga tttcaagcca tatactgtca gaagttgaac atctagctga ttttattg
//
LOCUS       DAUGQX010000096         1183 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUGQX010000096 DAUGQX010000000
VERSION     DAUGQX010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1183
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.096"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            68..155
                     /locus_tag="VIA51_001746"
     tRNA            68..155
                     /locus_tag="VIA51_001746"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:102..104,aa:Ser,seq:gct)
     gene            complement(601..882)
                     /locus_tag="VIA51_001747"
     CDS             complement(601..882)
                     /locus_tag="VIA51_001747"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8683667.1"
                     /translation="MTVLNYVNAGDAKNIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
BASE COUNT          372 a          147 c          252 g          412 t
ORIGIN      
        1 tggttagagc gcacgcctga taagcgtgag gtcggtggtt cgagtccact cgtgcccata
       61 tatatttgga gaattactca agaggctgaa gaggacggtt tgctaaatcg ttaggtcggg
      121 taactggcgc aagggttcga atcccttatt ctccgttttg taaacatatt aatggatgaa
      181 ttgtaaataa aggggaaaga agacggttat cgtctttttt tgtaatcttc aaaaccaact
      241 aaatagaata tttaaattgt tcattatttc gataactaaa atgataggct ctttgactac
      301 tgtagaggag taaaacattt aacttcatgg ctttgataag gttgttgact gtttctaatt
      361 tggccttaga gtagttgagt ttaagtatat tgctaatctt gttcttttct tttagaaaaa
      421 ttttaaaaat tgtctgaaaa atgggaagag caagagttga tagagttagg aataattatt
      481 gaaattcaga gatcttgtga gtaagagctt ttcttttcta gatgttagtt atgggcgtac
      541 gaaaaattgg gcaataaagc tattattgat gagcttccat gaatcatgct gtatgagttt
      601 tcagtaaagt ttgagagttc tatacgcgat aggttttata gcagaagtat ttatgattcg
      661 gatacgaaag cgagttatag cttgtctaag acgttggggg atatgaaaac aatcgaggat
      721 aattttagcc tgtagaaaaa gcatagtaat ctcatagtag tgggcactga gtatgcctat
      781 ggtaataact ttgacatgcc ttctaacctg tctggtataa tgaaagagat gattatgaat
      841 gttttttgcg tccccagcat ttacataatt taaaaccgtg atgctaaggt tttagattcc
      901 taatgaaatt atactataat cggattattc tatatgagtc tttctgaaat gatagtttgg
      961 tcgcttttca ttatagatcg tcatatggaa ctttttatat atgtttaaaa agactctata
     1021 atctttgagg tggatttacc tactacagaa agtatagaat taaaagttgt gaaagtttgc
     1081 gagtctttat gaattgtgat tgagtgatgg aatactaaga tttatagatg accagttttc
     1141 gatagttagc ttataaaaaa acaaggtctg actatactta tat
//
LOCUS       DAUGQX010000097         1175 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUGQX010000097 DAUGQX010000000
VERSION     DAUGQX010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.097"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            112..>1175
                     /locus_tag="VIA51_001748"
     CDS             112..>1175
                     /locus_tag="VIA51_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8683668.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNA"
BASE COUNT          421 a          184 c          188 g          382 t
ORIGIN      
        1 attttactaa cactagaatc ccgacaatta agtcaaaaaa agttatcact cacctaacct
       61 gaataaaaat ggtataatcg taaggatcac actatttatt aaggaaacat tatgaaaatt
      121 gttcagggag tacaacttca tctgattaag accaaacagt ttaaaaccaa tcatattacc
      181 tttcgttttt caggtgattt gaaccaaaaa acagtagcaa aaagagtctt agtggcacag
      241 atgttagcaa cagctaatga gtgttatcca actgttaggc agtttagaga aaaattagca
      301 cgactttatg gagctagctt gtcaactaac gtgttaacaa aagggttagt tcatattgtg
      361 gatatcgata ttacttttat tcaagataga tatgcttgca atggggaaaa aatactagat
      421 gaaatgattc agtttttaaa agatatcttg ttctcacccc tattatccat cgcccagtat
      481 cagcctaaag tttttgagac tgaaaaaaat aatttgatta actacatcga gtcagataga
      541 gaggattctt tttactacag ctctcttaag gtaaaagaat tgttttattg taataagaat
      601 ctacaaatgt cagaatatgg tagcccagaa ctaattgcaa aagagactgc ctatactagc
      661 tatcaagaat ttcataaaat gctcaatgaa gatcagattg atattttcat tttaggagat
      721 tttgatgatt atcgcgttgt tcagctaatt catcaatttc cacttgataa ccgaaataaa
      781 aacctaaatt tctttcattt acaaaattct gtcaatatta ttaaagaatc tattgaaaaa
      841 agagcagttc atcaatctat tttacaatta gcttatcact tcccttcagt ttttggacaa
      901 cgtgactatt atgctttagt tcttttaaat gggttgttag gctcttttgc acattcccgt
      961 ctctttataa aaattagaga agaagaagga cttgcttata gtatagggtg tcgttttgat
     1021 agttatacag gattatttga aatttatact ggaattgaca gtcaacatcg cactaaaacg
     1081 ttacaactaa tcatccaaga attaaatgcc attaaaatgg gacgattctc agaacaattg
     1141 attaaaaaga ccagatcgat gttgttgaat aatgc
//
LOCUS       DAUGQX010000098          965 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUGQX010000098 DAUGQX010000000
VERSION     DAUGQX010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.098"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(69..869)
                     /gene="sda3"
                     /locus_tag="VIA51_001749"
                     /gene_synonym="mf3"
     CDS             complement(69..869)
                     /gene="sda3"
                     /locus_tag="VIA51_001749"
                     /gene_synonym="mf3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase Sda3"
                     /protein_id="HEQ8683669.1"
                     /translation="MSKSNRRTWQGLVVILIAILTTFTTSTVTAARKIRNFPDTTEIL
                     LGTKATETPGILPFTGSYQLVLGDLDNLQRPTFAHIQLKDQDEPNIKRKGLKFNPPGW
                     HNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDSWLALHPNFWLDYKVTPVYHKNELVPRQVVLQYVGIDENGDLLQIKLGSEKES
                     VDNFGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNLETEEFEEAA"
BASE COUNT          295 a          168 c          156 g          346 t
ORIGIN      
        1 taaataaata atctaacatt tgggataatg ttcacaatct agatattttt attaagtata
       61 agtttatgtt aagccgcttc ttcaaactct tcggtttcta aattactatc ttcttcgttt
      121 tgagttgaat ctagcatcat tcctgtttgg taatccaatt cagctaaagg agatacgtta
      181 tctaatgtaa ctgatgttac tccaaagttg tctacacttt ctttttcact acctaactta
      241 atttgaagta gatctccatt ttcatcaatt ccaacatact gtagaactac ttggcgagga
      301 actaactcat ttttatgata aacaggagta actttatagt ctagccagaa gttagggtgt
      361 agagctaacc agctatctaa tctattttca taatagagca ttcctaaagg atttttgtca
      421 ctaaagccag tattaagata ttttgtcatt gtaactaggt ttttaggctc gtcatttaag
      481 ccgctaaatt ggtaaccaac taaatggcca cggtccatta accaagttgt ttttccatta
      541 gcgtcagtca atttgtaatt atgccagcca ggaggattga atttaagtcc ttttcgttta
      601 atattaggct catcttgatc ttttagctgg atgtgtgcga aggttggcct ttgcagattg
      661 tcaagatcgc ccaaaactaa ttggtagcta ccagtgaatg gtaagattcc tggtgtctca
      721 gtcgccttcg ttcctaacaa aatttccgtg gtatcaggga aatttctaat ttttctggct
      781 gccgtaacag tacttgtggt aaaagtggtg agaatagcta ttaaaataac aactaaacct
      841 tgccaagtac gacgatttga tttagacata tccatgtcct ccttttatta tttacaggtt
      901 aattatatca ctttaaatta aaaaaactta aaattaataa aattaattta tcaataatat
      961 tacgc
//
LOCUS       DAUGQX010000099          943 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUGQX010000099 DAUGQX010000000
VERSION     DAUGQX010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.099"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..328
                     /locus_tag="VIA51_001750"
     CDS             <1..328
                     /locus_tag="VIA51_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ8683670.1"
                     /translation="FSTEISKIYYIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISG
                     QVACFQSDNGKYFSTMPLINYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIE
                     NVKKNS"
     gene            383..>943
                     /locus_tag="VIA51_001751"
     CDS             383..>943
                     /locus_tag="VIA51_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8683671.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKIFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFL"
BASE COUNT          358 a          103 c          177 g          305 t
ORIGIN      
        1 tttttctact gaaatctcaa aaatttatta tataaagaca gacaagaaag aaaagcaaat
       61 ttatcattca atttggagtg atagtttagc aagtctatat ctaaatgagc tattgggaag
      121 gcatatttct ggacaggttg catgttttca atcagataat ggaaaatatt tttctacaat
      181 gcctttgata aattatgaaa aaaataatcg ggtacgagaa cagatagtga agggtatttt
      241 cgctaaacaa aaattattta aaattacagc agctacgcca gctaagattg cagaagcgat
      301 tatagaaaat gttaagaaaa actcatagtg tgggtgaatt tggggattaa tatgaagtat
      361 tgaaaaagga gtaagagtaa ttatgtttgt gataggcatt ccaactttaa atgaggcaga
      421 taatatcagt agattagtta aacaaattga tgagtatgct gtaaatttag ggaaagaaat
      481 tattattatt aattcggata gtaaaagtac agatggaact ccgcagattt ttttagaaac
      541 caaaacttat aacaccaaag tttcgatagt atcagaagct aaaggaaaag gttataatgt
      601 gagaaatatt ttcgaatatg caataaatca tgtgccgaat ttctccggtt taattttgat
      661 tgatggagac gttgtctcaa tgaaaaaaat gtggttagaa aagatgttta tagcaattga
      721 atctggaaat gatcttataa tcccaaatta tgctagaaaa tcttttgaag gaaatgcgac
      781 aaaccatttt atttatccca tgttagtgaa aattttcaaa cgtgatatgc cttatcaatg
      841 catctctggt gattttggat tttcaagagg attgataaaa gatttaactt tgaaatgtaa
      901 ttggcacaaa tatacattag gttacgggat agatattttt tta
//
LOCUS       DAUGQX010000100          920 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUGQX010000100 DAUGQX010000000
VERSION     DAUGQX010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..920
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.100"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..874)
                     /locus_tag="VIA51_001752"
     CDS             complement(<1..874)
                     /locus_tag="VIA51_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8683672.1"
                     /translation="MTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYF
                     DTENNIIKALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLG
                     SIETTSLMNFYGQEEKYHTITVGVHIKNYPAVAYMMAVVNVEQLDRANERYERIIIIV
                     MSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNRLESLFRK
                     PNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENY
                     ELVAKEYGKIFYFQN"
BASE COUNT          327 a          170 c          134 g          289 t
ORIGIN      
        1 ggttctgaaa ataaaatatt tttccatatt ctttagcaac tagttcataa ttctcaaaaa
       61 tagcattaaa aaaatctgta tctaaatgag tccactgtgg attaatgcca tcatctcgtc
      121 ttgctaaatt taataaatta gttgttaaga tgcgcatgtt gcgaacctcg tctaaactag
      181 aagcgagatg ctcactattt tctaatatcg tttcgttggg cttacgaaaa agcgattcca
      241 gacgattctg taagaccgcc aaaggggtcc ttaattcatg actagcattt tcaacaaaca
      301 ttttttgttt ttcatagctt tctaaaatag gttttctgct ccacttggct aaataaatac
      361 ttgctaaaat agaaattagc caaaaaacac tcataactat aataataatg cgctcataac
      421 gttcattagc gcggtctaat tgttccacat ttactactgc catcatatag gcaactgcag
      481 gataattttt gatatgaacc cctacagtta tcgtatggta tttttcttct tgtccataaa
      541 aattcattaa actggtggtt tcaatactcc ccaaccggcg tttatctaaa tgaaaatttt
      601 gatagttaga aaacgcatca aaagcattta aaattgttcc attagcacta aacaaaatga
      661 tatctgtatt agctgcaggc gttcctaata acttagaact atctgaatca ggcagcgcct
      721 taataatgtt attttcagta tcaaagtaaa aagaagatat tctagccatc gtacgattag
      781 catagctact tgcattatta ctaacagaaa ctaaactact gtcaactgac gaataaacgc
      841 caaaccgcat aatctgtaag ataataatag tcataatgac aaaaatacct gtaaaaaccg
      901 caaaaaaatg aaaaaagtgg
//
LOCUS       DAUGQX010000101          830 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUGQX010000101 DAUGQX010000000
VERSION     DAUGQX010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.101"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..730)
                     /locus_tag="VIA51_001753"
     rRNA            complement(<1..730)
                     /locus_tag="VIA51_001753"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          167 a          254 c          161 g          248 t
ORIGIN      
        1 caccggtgtt cctccatata tctacgcatt tcaccgctac acatggaatt ccactctccc
       61 cttctgcact caagttctcc agtttccaaa gcgtacattg gttgagccaa tgcctttaac
      121 ttcagactta aaaaaccgcc tgcgctcgct ttacgcccaa taaatccgga caacgctcgg
      181 gacctacgta ttaccgcggc tgctggcacg tagttagccg tccctttctg gttagttacc
      241 gtcacttggt ggattttcca ctcccaccat cattcttctc taacaacaga gctttacgat
      301 ccgaaaacct tcttcactca cgcggcgttg ctcggtcagg gttgccccca ttgccgaaga
      361 ttccctactg ctgcctcccg taggagtctg ggccgtgtct cagtcccagt gtggccgatc
      421 accctctcag gtcggctatg tatcgtcgcc ttggtgagcc tttacctcac caactagcta
      481 atacaacgca ggtccatctc atagtggagc aattgcccct tttaaattac taacatgcgt
      541 tagtctctct tatgcggtat tagctatcgt ttccaatagt tatcccccgc tatgaggtag
      601 gttacctacg cgttactcac ccgttcgcaa ctccttgaac cggtgcaagc accagttctc
      661 agcgttctac ttgcatgtat taggcacgcc gccagcgttc gtcctgagcc aggatcaaac
      721 tctctttaat ttgcgtttga acttactcgt tccttctgtc gctgacagat ttatttctcg
      781 tttcttgacg ggtaatatgt ctccatatca ccctcacgtt tggttcgtct
//
LOCUS       DAUGQX010000102          814 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUGQX010000102 DAUGQX010000000
VERSION     DAUGQX010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.102"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..534
                     /locus_tag="VIA51_001754"
     CDS             <1..534
                     /locus_tag="VIA51_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEQ8683673.1"
                     /translation="NSISVFEGYFNSLISYTRMLSEDRSVKLILVEELLSELHFEVDD
                     LLNINNIEFSICNRLIITSFYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGE
                     QIHFEIWNNGERFSDSTLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLN
                     NPARGGASAIISIKKKI"
     gene            682..>814
                     /locus_tag="VIA51_001755"
     CDS             682..>814
                     /locus_tag="VIA51_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEQ8683674.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     "
BASE COUNT          287 a          106 c          153 g          268 t
ORIGIN      
        1 aatagtattt ctgtttttga aggctatttc aattctttaa tatcttatac acgcatgctt
       61 tcagaggata gatcagtgaa actaatttta gttgaggagc tattaagtga gttacatttt
      121 gaagtcgatg acttattgaa tatcaataat attgaatttt ctatttgtaa tagacttatt
      181 atcacttctt tttatggaga tgaggaaaat ctgataagag ctctttctaa ccttttagtt
      241 aatgcaataa gatttatgcc cgtattagat aaaaaaatcg aagttatact gtctgagtca
      301 ggagagcaaa ttcattttga aatatggaat aatggtgagc gtttcagtga tagtacactg
      361 aaaaagggag ataaattatt ttacacggaa gattatagca gaggtaacaa acattatgga
      421 atcggtttgg catttgttaa aggcgttgct atcaaacacg gtgggaatct tcaattgaat
      481 aatccagcta gaggaggtgc tagcgccata atctcgataa aaaagaaaat ttaatagatt
      541 tgattgaaac tggagtattt caggcaaaaa atcgtaaatt tttggctaaa atactttttt
      601 tctgaacaaa ttctgaactt ggggtgtcat aataatcatg taaatatatc ggatgcaaaa
      661 acgtaagaga ggaactagaa aatgaataac acaattaaag actttgatct cgatttgaaa
      721 acaaataaaa aagacactgc tacaccttat gttggtagcc gttacctatg tacccctggt
      781 tcttgttgga aattagtttg ctttacaaca actg
//
LOCUS       DAUGQX010000103          811 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUGQX010000103 DAUGQX010000000
VERSION     DAUGQX010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.103"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..>811
                     /locus_tag="VIA51_001756"
     CDS             <1..>811
                     /locus_tag="VIA51_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEQ8683675.1"
                     /translation="KITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPL
                     KEAAINKLLCKAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNILK
                     INKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNES
                     RNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQN
                     LDSKKIIEAMGYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIIT"
BASE COUNT          289 a          126 c          133 g          263 t
ORIGIN      
        1 tgaaaattac agttgtaggc attggatacg ttggattatc gatagggctc ctacttgcaa
       61 aggaacacga cgtcaccttt tttgatattg ataataaaaa aattgattta ataaataaaa
      121 ggcaatcccc tcttaaagaa gcagctataa acaaactttt atgtaaggca aaaaatatta
      181 atgcaacttc ttctgaagaa ttagcatata aggatgcgac tttcataatc ttgtctttgc
      241 caaccaacct aaaatttaat aagcttgata cttccattat cgaaatttct gtaagtaata
      301 ttttaaagat aaacaaaaag gctacaattg taataaagtc gacagttcca attggtttta
      361 cagaatattt aaggaatcga tttcactaca acgatatcat tttttcacct gagttcctta
      421 gggaaggatc aactattcat gatcaattgt atccttcgag aactatagtt ggaaatgaat
      481 ctagaaattc tcaattattc ttagacatac taacagatat atcggttgaa aaagactcgc
      541 catctttatt agttggctct tctgaagcag aagcgataaa gttattttcg aatgcatact
      601 tggcacaaaa aattgctttt tttaatgagt tggatacgtt tgctgaaatg caaaatttgg
      661 actcaaaaaa aattattgag gctatgggat atgaccagag aataggaaat tcgcacaata
      721 atccttcttt cggttttggt gggtactgtc ttcctaagga tattaagcaa ttagagtatc
      781 attttaaaga aattccagca ccaattatta c
//
LOCUS       DAUGQX010000104          783 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUGQX010000104 DAUGQX010000000
VERSION     DAUGQX010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.104"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..669
                     /locus_tag="VIA51_001757"
     CDS             <1..669
                     /locus_tag="VIA51_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8683676.1"
                     /translation="IDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFKGYDLIL
                     LDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKPFSLKQF
                     VAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYREYEILE
                     LLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKTIRGIGY
                     KWDV"
BASE COUNT          272 a           92 c          153 g          266 t
ORIGIN      
        1 atagatgatg ataaagaaat tctgaagctt atgaagactg ctttggagat tgaaaattat
       61 catgttataa cctgtcaaga gatagaatta ccaatagttt ttgatgattt taaaggatat
      121 gatttgatct tattggatat catgatgcct aatataagtg gaactgagtt ttgttataaa
      181 attcgggaag aagttcattc tccaattatt tttgttagcg ctttagatgg cgataatgaa
      241 attgtccaag ctttaaatat agggggagac gattttattg tgaaaccatt tagcttaaaa
      301 caattcgtag ctaaagttaa ctctcatttg aagagagaag agagagcaaa gataaagaat
      361 gaggctgagg agagagtgaa gcgtagtttt ccacctatag aaatctatct agaggaacgt
      421 atgttatata ttgataaaca gccgttattc ctgacttata gagagtacga aattttagaa
      481 ttactgtcac gtcatccgta taaagttttc acaaaagaag agatatatga acaagtatat
      541 agcgatgaag cttcagcatt gtttcattct atttcagaat atatctatca gattagaatg
      601 aaattttcaa gttttggaat taatccaata aaaactattc gcgggattgg ttataaatgg
      661 gatgtttaaa aaatattcaa taaaaaatcg tgtttggcgc gccgtcgttg aaattgtctt
      721 tggagtttgt atcactgttt taatgattgc gataatatcg ctttcttttt caaagttaaa
      781 tat
//
LOCUS       DAUGQX010000105          769 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.105, whole genome shotgun sequence.
ACCESSION   DAUGQX010000105 DAUGQX010000000
VERSION     DAUGQX010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.105"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(63..136)
                     /locus_tag="VIA51_001758"
     tRNA            complement(63..136)
                     /locus_tag="VIA51_001758"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(100..102),aa:Arg,seq:acg)
     gene            complement(153..237)
                     /locus_tag="VIA51_001759"
     tRNA            complement(153..237)
                     /locus_tag="VIA51_001759"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(201..203),aa:Leu,seq:taa)
     gene            complement(246..317)
                     /locus_tag="VIA51_001760"
     tRNA            complement(246..317)
                     /locus_tag="VIA51_001760"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(283..285),aa:Gly,seq:gcc)
     gene            complement(330..402)
                     /locus_tag="VIA51_001761"
     tRNA            complement(330..402)
                     /locus_tag="VIA51_001761"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(367..369),aa:Thr,seq:tgt)
     gene            complement(413..494)
                     /locus_tag="VIA51_001762"
     tRNA            complement(413..494)
                     /locus_tag="VIA51_001762"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(458..460),aa:Leu,seq:tag)
     gene            complement(500..572)
                     /locus_tag="VIA51_001763"
     tRNA            complement(500..572)
                     /locus_tag="VIA51_001763"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(537..539),aa:Lys,seq:ttt)
     gene            complement(604..676)
                     /locus_tag="VIA51_001764"
     tRNA            complement(604..676)
                     /locus_tag="VIA51_001764"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(641..643),aa:Asp,seq:gtc)
     gene            complement(694..766)
                     /locus_tag="VIA51_001765"
     tRNA            complement(694..766)
                     /locus_tag="VIA51_001765"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          200 a          228 c          164 g          177 t
ORIGIN      
        1 aacctgcgac accttggtcc caaaccaagt actctaccaa gctgagctac ttcccgaact
       61 gatgcaccct agaggagtcg aacctctaac cgcctgattc gtagtcaggt actctatcca
      121 gttgagctaa gggtgctatt tcaaaaaatt aatgccgagg accggaatcg aaccggtacg
      181 atgtaaacca tcgcaggatt ttaagtcctg tgcgtctgcc agttccgcca ccccggctcc
      241 tcaaaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt gatgttctac
      301 cactgaacta cgttcgcaac taatctcaat gccggctaca tgacttgaac acgcgaccct
      361 ctgattacaa atcagatgct ctaccaactg agctaagccg gctaatcttt tatgcgggtt
      421 aagggacttg aacccccacg ccgttaagcg ccagatccta aatctggtgc gtctgccaat
      481 tccgccaaac ccgcttttat gacccgtact gggctcgaac cagtgaccca ttgattaaaa
      541 gtcaattgct ctaccaactg agctaacgag tctttccttc aaaaaatatg actactcttt
      601 gaacggtccc gacgggaatc gaacccgcga tcttcgccgt gacagggcga cgtgataacc
      661 gctacactac gggacctgta ttttccaata ctatgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcccatt
//
LOCUS       DAUGQX010000106          686 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.106, whole genome shotgun sequence.
ACCESSION   DAUGQX010000106 DAUGQX010000000
VERSION     DAUGQX010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..686
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.106"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            99..>686
                     /locus_tag="VIA51_001766"
     CDS             99..>686
                     /locus_tag="VIA51_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8683677.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLKTLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKD"
BASE COUNT          253 a           90 c          132 g          211 t
ORIGIN      
        1 tatattctaa caaatagtta aagttcggtt tttatttgta atatagataa aattgttaaa
       61 aaacaagcgt cttgtaaacc atttcaaagt atgatagaat gaaaaagtac cttaaaaaga
      121 taggaaaaat gatgacaaag atgtattatg atgaaaatcc agatagccta cacgatattc
      181 atgaagtaaa agtagagctg cttaatcatc cctttacttt tttgacggat tcaggtgtct
      241 tttcaaagaa aatggttgat ttcggtagcc aagtattatt aaagacacta aatttcaagg
      301 agaacgaacg tgtactggac ttaggttgcg gctatggccc tcttgggatt agtctagcca
      361 aggttcaaag ggtagacgca accttagtgg acatcaataa tcgtgctctt gatttagcta
      421 gaaaaaatgc aactaataac caagtggcag taactatttt tcaatcaaat atttatgaaa
      481 atattagtgg ccattttgag catattatta gtaatcctcc tattagagca ggaaagagag
      541 tagttcatag tattattgaa aaaagcatag attttttagt ggttaatggt gacttaacga
      601 ttgtgattca aaaaaaacaa ggagctccta gcgctaaagc aaaaatggca actatttttg
      661 gtaatgttga gatattaagg aaagat
//
LOCUS       DAUGQX010000107          581 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.107, whole genome shotgun sequence.
ACCESSION   DAUGQX010000107 DAUGQX010000000
VERSION     DAUGQX010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.107"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..525)
                     /gene="rgg4"
                     /locus_tag="VIA51_001767"
     CDS             complement(<1..525)
                     /gene="rgg4"
                     /locus_tag="VIA51_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEQ8683678.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     LILLELYLAYLDIEG"
BASE COUNT          186 a          119 c           69 g          207 t
ORIGIN      
        1 tccctcaata tcaagataag ctaaatataa ttctagaagt attaaatcat tttgcctaaa
       61 gcgtacctta gtctttattt gattaaaata ttcttgaagt aagtcaatgc caaagttagt
      121 attctcactc aataaagtat ctaaagttgc ctgtaaacaa tcaatgatta ttttctcttc
      181 ctctggtaat ttatcataat aatcctcaaa aatttcatca aactgctctt ctcgtacttg
      241 taattttcca tcatccatgt aagttggtgt ccttaagata aggtatttta attctttgta
      301 acgcttaggt agttctaaat cagcaccatc agttaagtaa ccgacactaa cgtttaaggc
      361 ttttgcaata aaaataacct tacttaaact tggtatggat tgacctagtt ctatccgtgc
      421 taattgacga acagaaagtt cagactcatc cccacacaag tcctcgcgac taatcctctt
      481 ttcaagtctt aacactttta cttttccacc aaaatgttct aacatggttt ctctccaaca
      541 actgttttct ttattatatc acagcgtcta attaaaaact a
//
LOCUS       DAUGQX010000108          507 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.108, whole genome shotgun sequence.
ACCESSION   DAUGQX010000108 DAUGQX010000000
VERSION     DAUGQX010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.108"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
BASE COUNT          172 a           54 c           96 g          185 t
ORIGIN      
        1 taaatttatt tataatattt ttgatacttt gagtagtaac gataatattt aattttttga
       61 tggattattt taattgactt tagtgggtta gatgccagtt tggatttttg atatttgtgt
      121 tgagtttaaa agataaaaac acttaatgaa aatctgtttt ttcttagaaa ggggaccagt
      181 atgattgaga cgctaatgag tacgttggaa atggttagaa aaaaatccta gtaggactgc
      241 aatcgaagat gactttgagg aatataaaaa gagaaatcta ccaatctttg tcagtgaaga
      301 tgatagtgtg atctattata gaccagggtt catttttaat gaattctatc ccaatatttc
      361 aggctggaga caagaactaa agactaagct tactagtatt tctttaattt ctttacattt
      421 tattggtgtt gttgacgaac aaaaaaaggg gggaatatct aggttctttt tctgatacat
      481 ctgaattctt aagtagacat ccaaaaa
//
LOCUS       DAUGQX010000109          504 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.109, whole genome shotgun sequence.
ACCESSION   DAUGQX010000109 DAUGQX010000000
VERSION     DAUGQX010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.109"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
BASE COUNT          161 a           66 c           93 g          184 t
ORIGIN      
        1 gtaatcattt tttgatttac agttattatc atgtgttatc tggcgactgt cctgtttaca
       61 agtaagttca caagtatggg ataaaatagt ataaactata gtaaatactg aatagtcaaa
      121 gaaaaatatc ggcataggtc agaagagctg atatgtttaa tactttttgc ggatatctac
      181 tgtatttaaa tgtatttgat atccttgtca aggatatacg tctaaacaag ttcaaaacga
      241 aatcatttgt gattatctta tcaggagttg actcttgata agatttttgt atatcagtac
      301 tgtggtacgt ttagatagct tggcagtgaa tttatagagt gtcaaacaac gagtgttttg
      361 tgttacacta accattagaa gagtctattg ttgagcatat caaggtgtta tcttttcgag
      421 ttgaggtatc atatctagtt gtaatgtcaa acatatctag tatatttaac tatcacgcca
      481 aacgcatgca gaaacttttg tttt
//
LOCUS       DAUGQX010000110          463 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.110, whole genome shotgun sequence.
ACCESSION   DAUGQX010000110 DAUGQX010000000
VERSION     DAUGQX010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.110"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..>463)
                     /locus_tag="VIA51_001768"
     CDS             complement(<1..>463)
                     /locus_tag="VIA51_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ8683679.1"
                     /translation="INSNQQFIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLI
                     EHSDTLLIHAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSN
                     SGILLTYAGTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIF"
BASE COUNT          163 a           83 c           61 g          156 t
ORIGIN      
        1 ggaaaattga aattttatca tcccaacttg ccttattaaa ttgtaatgaa cgattaaaaa
       61 atttgctaaa taatttaaac agtaaattgt ccgacaaaac agctgtcctt cttattttaa
      121 agaaagatgt ccctgcataa gttagtagta ttccagagtt cgaaccaaat attacctggt
      181 cattaccaat aaggtgatac ccatgttcta tacaaagcct tattgcaacc gtagtttttc
      241 cagcaccttt atctcctaat agtaaaattg aatggccaga taaaggatta taaactgctg
      301 ctgcatgaat taataaggtg tcactatgtt caatcaagag acattcagct aagtactctc
      361 caatgtagta taatgaaatt ccttctttaa aatactttaa tcttccataa actaaaatat
      421 ttccattgcc atcatattct ataaattgct gattgctgtt aat
//
LOCUS       DAUGQX010000111          454 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.111, whole genome shotgun sequence.
ACCESSION   DAUGQX010000111 DAUGQX010000000
VERSION     DAUGQX010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.111"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            127..393
                     /locus_tag="VIA51_001769"
     CDS             127..393
                     /locus_tag="VIA51_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8683680.1"
                     /translation="MTYFRLKKELNWSLRNKGIVVYEGNQKLQIAINTGKNNSEKVFF
                     DTFFEVVRAAATFSTAKNICFGLGLLRSQKQEIGYHISRVVHVF"
BASE COUNT          150 a           65 c           87 g          152 t
ORIGIN      
        1 tcattatagc aataaacaaa taggagggca attgtttaac tggttaatta gaatttttgt
       61 tattttcagg aagatactca gggctttttt ataagttgat gtattaacaa aagataaaga
      121 ggtttcatga cttattttag attaaaaaaa gaattaaact ggtcactaag aaataaagga
      181 attgtagttt acgaagggaa tcaaaaactt cagatagcca ttaatacagg taaaaataac
      241 agtgaaaaag tcttttttga tacttttttt gaggtggttc gggcggcagc gactttctcc
      301 acagcaaaaa acatctgttt tggtcttggc ttacttcgtt cgcagaaaca ggaaatcggg
      361 tatcacatta gcagagtagt tcatgttttt tgagcatcac actgggtctg tctacgttct
      421 aaaagctttt gtcatttttg tatcataccc ccta
//
LOCUS       DAUGQX010000112          427 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.112, whole genome shotgun sequence.
ACCESSION   DAUGQX010000112 DAUGQX010000000
VERSION     DAUGQX010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.112"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(64..137)
                     /locus_tag="VIA51_001770"
     tRNA            complement(64..137)
                     /locus_tag="VIA51_001770"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(101..103),aa:Met,seq:cat)
     gene            complement(147..236)
                     /locus_tag="VIA51_001771"
     tRNA            complement(147..236)
                     /locus_tag="VIA51_001771"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(198..200),aa:Ser,seq:tga)
     gene            complement(259..332)
                     /locus_tag="VIA51_001772"
     tRNA            complement(259..332)
                     /locus_tag="VIA51_001772"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(296..298),aa:Ile,seq:cat)
     gene            complement(353..426)
                     /locus_tag="VIA51_001773"
     tRNA            complement(353..426)
                     /locus_tag="VIA51_001773"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(390..392),aa:Met,seq:cat)
BASE COUNT          114 a          120 c           98 g           95 t
ORIGIN      
        1 atggagcttc aatccattgc tctaccaact gagctaccga gccaacaact acatacttat
       61 gtattgcggg agcaggattt gaacctacga ccttcgggtt atgagcccga cgagctacct
      121 aactgctcca tcccgcgata gttaaaagga ggatgtggga ttcgaaccca cgcacgcttt
      181 tacacgcctg acggttttca agaccgttcc cttcagccgg acttgggtaa tcctccaaaa
      241 taatgattat ctatgatatg gaccttgtag gactcgaacc tacgaccgct cggttatgag
      301 ccgagtgctc taaccagttg agctaaaggt cccaagtcat ccataaaaat aatagcggcg
      361 aaggggatcg aacccccgac ctcccgggta tgaaccggac gctctagcca gctgagctac
      421 accgcca
//
LOCUS       DAUGQX010000113          425 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.113, whole genome shotgun sequence.
ACCESSION   DAUGQX010000113 DAUGQX010000000
VERSION     DAUGQX010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.113"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..391
                     /locus_tag="VIA51_001774"
     CDS             <1..391
                     /locus_tag="VIA51_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8683681.1"
                     /translation="GSCIDFGEEGAVGRGNKTHGIISSFRPNTMEAPAGKNCTYFVGK
                     VWGFLSDTIAKEIYEAFNTPCQIIMQLNIGSKLYRPTHLFIQTEESVDQERVLEIVNR
                     HLNNGKQNTNLILSTQHFIPKTNVYDG"
BASE COUNT          150 a           53 c           77 g          145 t
ORIGIN      
        1 aggttcttgt attgattttg gagaagaagg tgcagttggt cgaggtaata aaactcatgg
       61 tatcatatca agttttaggc caaatactat ggaagcacca gctggaaaaa attgtactta
      121 ttttgtagga aaggtttggg gatttttgtc tgatactatt gccaaagaaa tttatgaagc
      181 attcaatact ccctgtcaaa tcattatgca attaaatatt ggatcaaaat tgtatagacc
      241 aacccattta tttattcaga cagaagaaag tgttgatcaa gaaagagtat tagaaattgt
      301 taacaggcat ttaaataatg gtaaacaaaa tactaattta atcttgtcaa ctcaacattt
      361 tattcctaaa accaatgtct atgatggata aaactgtttt atattttggg ttggttgaaa
      421 tttct
//
LOCUS       DAUGQX010000114          423 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.114, whole genome shotgun sequence.
ACCESSION   DAUGQX010000114 DAUGQX010000000
VERSION     DAUGQX010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.114"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(<1..422)
                     /locus_tag="VIA51_001775"
     CDS             complement(<1..422)
                     /locus_tag="VIA51_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HEQ8683682.1"
                     /translation="MDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYETDV
                     SYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQAWQE
                     QRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRG"
BASE COUNT          114 a           87 c           71 g          151 t
ORIGIN      
        1 atccctctta tagacatatt aaagagtaga aacggtactg ctttgtccga taactcttct
       61 acgtgatacc agtatttact cggacgataa gtaaatggac tgtcatttaa tcgttgttct
      121 tgccatgctt ggataagtat cccacccgtc ccgactgcta cctcgtagta ttgattacca
      181 cttattattt tagataatag tgtactaacc gatttaggcg taaagtcttg ctttttattt
      241 ttgcggtcag cttgttcttc ctcaaaatat tgcataaacc agtcgtaaga tacatctgtt
      301 tcatatttca aaaactgtct aaatatatcc tcacgactat ctttatcaaa gagtatgtcc
      361 gtaagtcgtt tgggtgcttt ataaacttcg tcgatgccta gtatgcgatg tatctcatcg
      421 atc
//
LOCUS       DAUGQX010000115          419 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.115, whole genome shotgun sequence.
ACCESSION   DAUGQX010000115 DAUGQX010000000
VERSION     DAUGQX010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.115"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            <1..353
                     /locus_tag="VIA51_001776"
     CDS             <1..353
                     /locus_tag="VIA51_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEQ8683683.1"
                     /translation="GIGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIE
                     SMHWLLDVVYHEDHHQTLDKRAAFNLNLIRKMCLYFLKVMVFPKKDLSYRRKQRYISV
                     HLEDYLVQLFGERG"
BASE COUNT          134 a           63 c           92 g          130 t
ORIGIN      
        1 gtggtattgg gatgactcgt aacacgattg ataaggatgg tcagctgagt caagagaatc
       61 gttattttat ctttagcttt aagccggatg tcctcacatt tgccaattgt gtacgaggtc
      121 attggcagat agagagtatg cactggttat tggacgttgt ttatcatgaa gatcatcatc
      181 agacattgga taaaagagcc gcatttaacc taaatcttat ccgaaaaatg tgcttatatt
      241 ttctcaaagt gatggtattt cctaaaaaag acctcagtta tcgtcgcaaa caacggtata
      301 tttctgtcca tttggaagat tatttagtcc aattatttgg agaaagaggc taagcagatg
      361 attgatttaa aaaggaatct tttcaaaatt gatgtccggg cacaaaagga tgaagagaa
//
LOCUS       DAUGQX010000116          353 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00071598
            SAMN33608098-rid17956303.denovo.116, whole genome shotgun sequence.
ACCESSION   DAUGQX010000116 DAUGQX010000000
VERSION     DAUGQX010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608098
            Sequence Read Archive: SRR23751585
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723341.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723341.1
            Genome Coverage       :: 402x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:11:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,777
            CDSs (total)                      :: 1,740
            Genes (coding)                    :: 1,697
            CDSs (with protein)               :: 1,697
            Genes (RNA)                       :: 37
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 30
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 29 of 43
            Pseudo Genes (incomplete)         :: 15 of 43
            Pseudo Genes (internal stop)      :: 14 of 43
            Pseudo Genes (multiple problems)  :: 13 of 43
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608098-rid17956303.denovo.116"
                     /strain="AUSMDU00071598"
                     /serotype="EMM1.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2017"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST28"
     gene            complement(161..340)
                     /locus_tag="VIA51_001777"
     CDS             complement(161..340)
                     /locus_tag="VIA51_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8683684.1"
                     /translation="MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGE
                     VVTDEKVEEVLMELE"
BASE COUNT          101 a           73 c           60 g          119 t
ORIGIN      
        1 atatgcactt tgttttactc acaaggagag gaggggattg ctggtagcta tctcaccgtt
       61 ttcatccttt gcaagacact taaacgttgg tatttttaaa atatagaaag gatagaaaaa
      121 gatgaaaaaa taaaaataaa cgggtgattg acgggtaatg ttactccaat tccatcaaca
      181 cttcttccac tttttcatct gtcacaactt ctccattctt tactttctca tgtggcaaca
      241 cataatcaaa gatctgtccg tttttgcgca caatcgctac tgtgtctcct gtgatatacc
      301 catggtcgat tgcttgctta aattcgtcgt atgttagcat agattacctc ctt
//
