LOCUS       DAUGSW010000001       121388 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUGSW010000001 DAUGSW010000000
VERSION     DAUGSW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 121388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 121388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..121388
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.001"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            539..1066
                     /locus_tag="VIB18_000001"
     CDS             539..1066
                     /locus_tag="VIB18_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEQ8765046.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1066..2184
                     /gene="yqeH"
                     /locus_tag="VIB18_000002"
     CDS             1066..2184
                     /gene="yqeH"
                     /locus_tag="VIB18_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEQ8765047.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2209..2517
                     /gene="yhbY"
                     /locus_tag="VIB18_000003"
     CDS             2209..2517
                     /gene="yhbY"
                     /locus_tag="VIB18_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEQ8765048.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTFLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2586..3218
                     /locus_tag="VIB18_000004"
     CDS             2586..3218
                     /locus_tag="VIB18_000004"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEQ8765049.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLCMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKQVLDYITQEGLYQ"
     gene            3215..3808
                     /gene="yqeK"
                     /locus_tag="VIB18_000005"
     CDS             3215..3808
                     /gene="yqeK"
                     /locus_tag="VIB18_000005"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEQ8765050.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWDNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3832..4185
                     /gene="rsfS"
                     /locus_tag="VIB18_000006"
     CDS             3832..4185
                     /gene="rsfS"
                     /locus_tag="VIB18_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEQ8765051.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            4233..4976
                     /locus_tag="VIB18_000007"
     CDS             4233..4976
                     /locus_tag="VIB18_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8765052.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DCVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            5230..6336
                     /locus_tag="VIB18_000008"
     CDS             5230..6336
                     /locus_tag="VIB18_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEQ8765053.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDVID
                     YQKLIKVYEKKSEQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6818..7534
                     /locus_tag="VIB18_000009"
     CDS             6818..7534
                     /locus_tag="VIB18_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8765054.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7737..8579
                     /locus_tag="VIB18_000010"
     CDS             7737..8579
                     /locus_tag="VIB18_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8765055.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKKAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8906..9751
                     /locus_tag="VIB18_000011"
     CDS             8906..9751
                     /locus_tag="VIB18_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8765056.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKLEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            10001..11065
                     /locus_tag="VIB18_000012"
     CDS             10001..11065
                     /locus_tag="VIB18_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765057.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDITVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKVQLSANALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11066..11758
                     /locus_tag="VIB18_000013"
     CDS             11066..11758
                     /locus_tag="VIB18_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765058.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSVFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11812..13182)
                     /gene="brnQ"
                     /locus_tag="VIB18_000014"
     CDS             complement(11812..13182)
                     /gene="brnQ"
                     /locus_tag="VIB18_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEQ8765059.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKVIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VITSFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEMTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFIDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
     gene            13416..14630
                     /gene="sstT"
                     /locus_tag="VIB18_000015"
     CDS             13416..14630
                     /gene="sstT"
                     /locus_tag="VIB18_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEQ8765060.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(14685..15359)
                     /locus_tag="VIB18_000016"
     CDS             complement(14685..15359)
                     /locus_tag="VIB18_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEQ8765061.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(15369..16760)
                     /locus_tag="VIB18_000017"
     CDS             complement(15369..16760)
                     /locus_tag="VIB18_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEQ8765062.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSLEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(16829..17542)
                     /gene="rsmG"
                     /locus_tag="VIB18_000018"
     CDS             complement(16829..17542)
                     /gene="rsmG"
                     /locus_tag="VIB18_000018"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEQ8765063.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            17692..18249
                     /locus_tag="VIB18_000019"
     CDS             17692..18249
                     /locus_tag="VIB18_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEQ8765064.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            18296..19192
                     /gene="htpX"
                     /locus_tag="VIB18_000020"
     CDS             18296..19192
                     /gene="htpX"
                     /locus_tag="VIB18_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEQ8765065.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGMIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            19426..19959
                     /locus_tag="VIB18_000021"
     CDS             19426..19959
                     /locus_tag="VIB18_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEQ8765066.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            20226..20912
                     /gene="covR"
                     /locus_tag="VIB18_000022"
                     /gene_synonym="csrR"
     CDS             20226..20912
                     /gene="covR"
                     /locus_tag="VIB18_000022"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEQ8765067.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            20918..22420
                     /gene="covS"
                     /locus_tag="VIB18_000023"
                     /gene_synonym="csrS"
     CDS             20918..22420
                     /gene="covS"
                     /locus_tag="VIB18_000023"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEQ8765068.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            22635..23129
                     /gene="nrdR"
                     /locus_tag="VIB18_000024"
     CDS             22635..23129
                     /gene="nrdR"
                     /locus_tag="VIB18_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEQ8765069.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            23113..24288
                     /locus_tag="VIB18_000025"
     CDS             23113..24288
                     /locus_tag="VIB18_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEQ8765070.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQITVPSQARNISKRFSDIFGVQGNLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            24289..25191
                     /gene="dnaI"
                     /locus_tag="VIB18_000026"
     CDS             24289..25191
                     /gene="dnaI"
                     /locus_tag="VIB18_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEQ8765071.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            25254..26564
                     /gene="der"
                     /locus_tag="VIB18_000027"
     CDS             25254..26564
                     /gene="der"
                     /locus_tag="VIB18_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEQ8765072.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            26771..29869
                     /locus_tag="VIB18_000028"
     CDS             26771..29869
                     /locus_tag="VIB18_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8765073.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASGTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIKRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRSFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMN
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            30111..30713
                     /locus_tag="VIB18_000029"
     CDS             30111..30713
                     /locus_tag="VIB18_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765074.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSDDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            30753..32081
                     /locus_tag="VIB18_000030"
     CDS             30753..32081
                     /locus_tag="VIB18_000030"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEQ8765075.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            32127..32609
                     /locus_tag="VIB18_000031"
     CDS             32127..32609
                     /locus_tag="VIB18_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8765076.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISDSQHGGTLWYQMIWKL
                     "
     gene            32721..34295
                     /gene="mltG"
                     /locus_tag="VIB18_000032"
     CDS             32721..34295
                     /gene="mltG"
                     /locus_tag="VIB18_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEQ8765077.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKDAVMTSEAIKPTLLSE
                     KENSSLKTTSKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            34368..34850
                     /gene="greA"
                     /locus_tag="VIB18_000033"
     CDS             34368..34850
                     /gene="greA"
                     /locus_tag="VIB18_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEQ8765078.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(35469..36392)
                     /gene="yidC"
                     /locus_tag="VIB18_000034"
     CDS             complement(35469..36392)
                     /gene="yidC"
                     /locus_tag="VIB18_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8765079.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(36474..36752)
                     /locus_tag="VIB18_000035"
     CDS             complement(36474..36752)
                     /locus_tag="VIB18_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEQ8765080.1"
                     /translation="MQKVRLIVSGRVQGVGFRHATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGN"
     gene            37013..37750
                     /locus_tag="VIB18_000036"
     CDS             37013..37750
                     /locus_tag="VIB18_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEQ8765081.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMAERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            37789..38289
                     /locus_tag="VIB18_000037"
     CDS             37789..38289
                     /locus_tag="VIB18_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8765082.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            38304..38993
                     /locus_tag="VIB18_000038"
     CDS             38304..38993
                     /locus_tag="VIB18_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEQ8765083.1"
                     /translation="MNDHIIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            39171..39413
                     /locus_tag="VIB18_000039"
     CDS             39171..39413
                     /locus_tag="VIB18_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEQ8765084.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            39591..40385
                     /gene="racE"
                     /locus_tag="VIB18_000040"
     CDS             39591..40385
                     /gene="racE"
                     /locus_tag="VIB18_000040"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEQ8765085.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPAEQIREYTWDLVRFLLTKNVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGSSA
                     AIKSTTKGQVGVIGTPMTIASDIYRQKIQLLAPTVEVASLACPKFVPIVESNEIRSSV
                     AKKVVYESLTPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            40382..41368
                     /locus_tag="VIB18_000041"
     CDS             40382..41368
                     /locus_tag="VIB18_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEQ8765086.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLFLITFIIDMINQETQREIKVIPHASTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDTILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVKAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            41347..41868
                     /locus_tag="VIB18_000042"
     CDS             41347..41868
                     /locus_tag="VIB18_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEQ8765087.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            41865..42326
                     /locus_tag="VIB18_000043"
     CDS             41865..42326
                     /locus_tag="VIB18_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8765088.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            42323..43069
                     /gene="xerD"
                     /locus_tag="VIB18_000044"
     CDS             42323..43069
                     /gene="xerD"
                     /locus_tag="VIB18_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEQ8765089.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLIGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPMTLEKYYKS"
     gene            43069..43773
                     /locus_tag="VIB18_000045"
     CDS             43069..43773
                     /locus_tag="VIB18_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEQ8765090.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKNNHTV
                     IERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQFSNFGAIILRKEKK"
     gene            43770..44321
                     /locus_tag="VIB18_000046"
     CDS             43770..44321
                     /locus_tag="VIB18_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEQ8765091.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            44442..45164
                     /locus_tag="VIB18_000047"
     CDS             44442..45164
                     /locus_tag="VIB18_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8765092.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATAVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            45161..45424
                     /gene="yidD"
                     /locus_tag="VIB18_000048"
     CDS             45161..45424
                     /gene="yidD"
                     /locus_tag="VIB18_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEQ8765093.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            45602..46150
                     /locus_tag="VIB18_000049"
     CDS             45602..46150
                     /locus_tag="VIB18_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEQ8765094.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      46259..46382
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46461..47024
                     /locus_tag="VIB18_000050"
     CDS             46461..47024
                     /locus_tag="VIB18_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8765095.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFSLVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            47026..47679
                     /locus_tag="VIB18_000051"
     CDS             47026..47679
                     /locus_tag="VIB18_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8765096.1"
                     /translation="MMTNKQTNFLIASFALLTFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQILLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILVIGLSRIYLGVHYPSDILAGFVLGFGILQFIYPFYKQKRFEWRFLLKQD"
     gene            47972..48892
                     /locus_tag="VIB18_000052"
     CDS             47972..48892
                     /locus_tag="VIB18_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEQ8765097.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            48931..49485
                     /locus_tag="VIB18_000053"
     CDS             48931..49485
                     /locus_tag="VIB18_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8765098.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            49618..50952
                     /locus_tag="VIB18_000054"
     CDS             49618..50952
                     /locus_tag="VIB18_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEQ8765099.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVREIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            51030..51821
                     /gene="pflA"
                     /locus_tag="VIB18_000055"
     CDS             51030..51821
                     /gene="pflA"
                     /locus_tag="VIB18_000055"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEQ8765100.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPDLTDIDDHLTRLGEFVKTLKNVYKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            51952..52887
                     /locus_tag="VIB18_000056"
     CDS             51952..52887
                     /locus_tag="VIB18_000056"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEQ8765101.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVIDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKSIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDISEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            52963..53616
                     /locus_tag="VIB18_000057"
     CDS             52963..53616
                     /locus_tag="VIB18_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEQ8765102.1"
                     /translation="MITIFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMFFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRSQLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(53661..54698)
                     /locus_tag="VIB18_000058"
     CDS             complement(53661..54698)
                     /locus_tag="VIB18_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8765103.1"
                     /translation="MLFMVNKKRRPLLKSHRHLLRLYTSLILLLVSLMGLALSLGESH
                     LSFLDLIHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(54659..55711)
                     /locus_tag="VIB18_000059"
     CDS             complement(54659..55711)
                     /locus_tag="VIB18_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8765104.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFTILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(55701..56633)
                     /locus_tag="VIB18_000060"
     CDS             complement(55701..56633)
                     /locus_tag="VIB18_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8765105.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEDKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(56659..57441)
                     /locus_tag="VIB18_000061"
     CDS             complement(56659..57441)
                     /locus_tag="VIB18_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765106.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(57687..59132)
                     /locus_tag="VIB18_000062"
     CDS             complement(57687..59132)
                     /locus_tag="VIB18_000062"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEQ8765107.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGANLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIARHYL"
     gene            59220..60854
                     /locus_tag="VIB18_000063"
     CDS             59220..60854
                     /locus_tag="VIB18_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEQ8765108.1"
                     /translation="MPTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYVFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            61022..61651
                     /gene="upp"
                     /locus_tag="VIB18_000064"
     CDS             61022..61651
                     /gene="upp"
                     /locus_tag="VIB18_000064"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEQ8765109.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            61875..62465
                     /locus_tag="VIB18_000065"
     CDS             61875..62465
                     /locus_tag="VIB18_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEQ8765110.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            62960..63235
                     /locus_tag="VIB18_000066"
     CDS             62960..63235
                     /locus_tag="VIB18_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEQ8765111.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            63484..64119
                     /locus_tag="VIB18_000067"
     CDS             63484..64119
                     /locus_tag="VIB18_000067"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEQ8765112.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQDILTTREPGG
                     VAISEHIRELILDINHTAMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            64137..65012
                     /locus_tag="VIB18_000068"
     CDS             64137..65012
                     /locus_tag="VIB18_000068"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEQ8765113.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHINAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            65031..65270
                     /locus_tag="VIB18_000069"
     CDS             65031..65270
                     /locus_tag="VIB18_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
                     /protein_id="HEQ8765114.1"
                     /translation="MGKRSLSKDLPVATKIAAHRGKKAFEENTAFATDLMKEVSRLIT
                     QNQLEMTFINSVFLLDQHVVLIPFSAEEHMDFYNC"
     gene            65675..65998
                     /gene="yabA"
                     /locus_tag="VIB18_000070"
     CDS             65675..65998
                     /gene="yabA"
                     /locus_tag="VIB18_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEQ8765115.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            66003..66866
                     /gene="rsmI"
                     /locus_tag="VIB18_000071"
     CDS             66003..66866
                     /gene="rsmI"
                     /locus_tag="VIB18_000071"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEQ8765116.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQADSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            66893..67285
                     /locus_tag="VIB18_000072"
     CDS             66893..67285
                     /locus_tag="VIB18_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765117.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(67332..67961)
                     /locus_tag="VIB18_000073"
     CDS             complement(67332..67961)
                     /locus_tag="VIB18_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEQ8765118.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGITAENCQSLSQLTGTAIVHGTKII"
     gene            68261..68617
                     /locus_tag="VIB18_000074"
     CDS             68261..68617
                     /locus_tag="VIB18_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEQ8765119.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGK
                     VLQVGYRKPYQELDLG"
     gene            complement(68691..69518)
                     /gene="xth"
                     /locus_tag="VIB18_000075"
     CDS             complement(68691..69518)
                     /gene="xth"
                     /locus_tag="VIB18_000075"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEQ8765120.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPSKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDTQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYCLASNRIVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            69753..70934
                     /gene="lctO"
                     /locus_tag="VIB18_000076"
     CDS             69753..70934
                     /gene="lctO"
                     /locus_tag="VIB18_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEQ8765121.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSTGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            71197..76140
                     /gene="scpC"
                     /locus_tag="VIB18_000077"
     CDS             71197..76140
                     /gene="scpC"
                     /locus_tag="VIB18_000077"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEQ8765122.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPT
                     ITNHAQQQAQHLTNTELSSAESKSQDTSQITLKTNREKEQSQDLVSEPTTTELADTDA
                     ASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFGDFD
                     EDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKY
                     ESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIED
                     AVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDP
                     LATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVD
                     FKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKDKIALIERDPNKTYDEMIALAKKHG
                     ALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLVFDSVVS
                     KAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIA
                     GASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNI
                     DGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQ
                     KGRFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRF
                     RDSQDAQLNRVNIPFVGFKGQFENLVVAEESIYRLKSQGKTGFYFDESGPKDDIYVGK
                     HFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNN
                     QDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTL
                     LGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDP
                     ETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVADNKTFVERQA
                     DGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKE
                     TLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKG
                     LKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAVESTAWYGITARGSKVMPGDYQ
                     YVVTYRDEHGKVHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVRE
                     EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVED
                     RAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYY
                     NNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATSQ
                     ITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRI
                     EGNTKVNTLPNEVHELSLRLVKVGDASDSIGDHKVMSKNNSQALTASATPTKTTTSAT
                     AKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            76918..77625
                     /locus_tag="VIB18_000078"
     CDS             76918..77625
                     /locus_tag="VIB18_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEQ8765123.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMLVFMLGQSFTYFMHRWATKKGLHWYLLSSVIL
                     TGIAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNYELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            77865..79865
                     /gene="metG"
                     /locus_tag="VIB18_000079"
     CDS             77865..79865
                     /gene="metG"
                     /locus_tag="VIB18_000079"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEQ8765124.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLEPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSVKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKFYPNEQELVGKKLQIVA
                     NLKPRKMMKQYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            80360..81373
                     /gene="nrdF"
                     /locus_tag="VIB18_000080"
     CDS             80360..81373
                     /gene="nrdF"
                     /locus_tag="VIB18_000080"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8765125.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            81377..81865
                     /gene="nrdI"
                     /locus_tag="VIB18_000081"
     CDS             81377..81865
                     /gene="nrdI"
                     /locus_tag="VIB18_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8765126.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFAIAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            81832..84012
                     /gene="nrdE"
                     /locus_tag="VIB18_000082"
     CDS             81832..84012
                     /gene="nrdE"
                     /locus_tag="VIB18_000082"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8765127.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNVANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(84218..84970)
                     /locus_tag="VIB18_000083"
     CDS             complement(84218..84970)
                     /locus_tag="VIB18_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEQ8765128.1"
                     /translation="MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKVAETLIKKRWGKGLVYPRAEQEAMAAYTCQQAAPINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            85424..85879
                     /locus_tag="VIB18_000084"
     CDS             85424..85879
                     /locus_tag="VIB18_000084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765129.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMGRPVKAEAVTQTTEGVQQI
                     EENAEDRDIKEEYMKRMGITDSDLEDEEQAYLKKRVQGYLKGYADGQKLNAPEQPSDY
                     NPSSDDDYNDGYTDGYSRSWHKTNQPIRTALYDAFEWFVGWLERFFEGR"
     gene            complement(86111..87547)
                     /locus_tag="VIB18_000085"
                     /pseudo
     CDS             complement(86111..87547)
                     /locus_tag="VIB18_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            88016..88468
                     /locus_tag="VIB18_000086"
     CDS             88016..88468
                     /locus_tag="VIB18_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765130.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMTRPVKAEVTVSEGESASHQ
                     TTKSTSLGNLFLSSEGGENGRYDYDFWHRLGYSEGYEKGKESDGPGIDNIDVPENVLD
                     KGAYKDGYEGGHEAGWRDTHPIESLLDMAWQFLTYAFNNLFGFGQNTQ"
     gene            complement(88767..90012)
                     /locus_tag="VIB18_000087"
                     /pseudo
     CDS             complement(88767..90012)
                     /locus_tag="VIB18_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            90469..91101
                     /locus_tag="VIB18_000088"
     CDS             90469..91101
                     /locus_tag="VIB18_000088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765131.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMEQPVKADGAGNSDKAEFHG
                     TPYDLGVRDGYRKGLEDGKVAGKQTGTTSEPPKGSDSPKTSPYTEENQKARYTRAYQE
                     WYLHGYRAGWHETHNQISERGEEENKTPEASHEKEGRQEENRTPEASHEKEGRQEENR
                     TPEASHEKEGRQEESGSQEEDILSPIVETVETIIEAVLEAWTYVFNWFNS"
     gene            91545..91964
                     /locus_tag="VIB18_000089"
     CDS             91545..91964
                     /locus_tag="VIB18_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765132.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMTRPVKAEVVTQTPEGKVTK
                     AEGRGNVDDEAQKYQRRWEAGHKKGYEKGKEPDSPREPQEIPEGTGDDYGDGYSDGYS
                     TGYGEGWYDSHPITALLDMAWYYLTYAFGALFGGANS"
     gene            92154..92405
                     /locus_tag="VIB18_000090"
     CDS             92154..92405
                     /locus_tag="VIB18_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765133.1"
                     /translation="MPEKKVLPVLSMVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLILAALAVAVVAYAYYDPTVIPY"
     gene            complement(92499..93131)
                     /locus_tag="VIB18_000091"
     CDS             complement(92499..93131)
                     /locus_tag="VIB18_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765134.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDITFKQVPGQQTIPGITVKSF
                     KVGDSTISVQLGSYEYVYGSIKHRDNSVDKINPRAKEVKVTCPTTSNGCIERKWMVSG
                     NRADGSGYWSVQLTKELQEGDIVTLSFADDGNLIFGKLVFEDEKTQNTRLQAEKAQEQ
                     EEEKKRDNELRKQLEESMLKQIREEDHKSWHQRLSESIQGQWWNFKGLFQ"
     gene            93491..93727
                     /locus_tag="VIB18_000092"
     CDS             93491..93727
                     /locus_tag="VIB18_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEQ8765135.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            93720..94418
                     /locus_tag="VIB18_000093"
     CDS             93720..94418
                     /locus_tag="VIB18_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEQ8765136.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLNGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTKPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            94494..95453
                     /locus_tag="VIB18_000094"
     CDS             94494..95453
                     /locus_tag="VIB18_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8765137.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKTAKDLA
                     KAYKMPLATSKYEAVLGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVHYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVELSLHGHEAQVVNHNKH
                     DHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMSVLERAVHS"
     gene            95786..97123
                     /locus_tag="VIB18_000095"
     CDS             95786..97123
                     /locus_tag="VIB18_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8765138.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            97296..98678
                     /gene="glmU"
                     /locus_tag="VIB18_000096"
     CDS             97296..98678
                     /gene="glmU"
                     /locus_tag="VIB18_000096"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEQ8765139.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKAVTVIGHKSEKVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFHNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGQGSIITNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDNALTAAGSTISKTVPADSIVIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            98709..99263
                     /locus_tag="VIB18_000097"
     CDS             98709..99263
                     /locus_tag="VIB18_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8765140.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIESVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLHEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            99263..99514
                     /locus_tag="VIB18_000098"
     CDS             99263..99514
                     /locus_tag="VIB18_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765141.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVDFDTKVMTLPEKDEKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            99534..100229
                     /locus_tag="VIB18_000099"
     CDS             99534..100229
                     /locus_tag="VIB18_000099"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEQ8765142.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQTLMTFLENLPV"
     gene            100380..100721
                     /locus_tag="VIB18_000100"
     CDS             100380..100721
                     /locus_tag="VIB18_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765143.1"
                     /translation="MILKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNGGYRQDLTN
                     QKSKLQYSKDNAKLQLRNILNGYQDDLGKHYSSYYYYNLRIVMGLSSEQKIEKYYEEL
                     KNKLHNMYKHY"
     gene            complement(100820..101467)
                     /locus_tag="VIB18_000101"
     CDS             complement(100820..101467)
                     /locus_tag="VIB18_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEQ8765144.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYGDKDLIIPENIAKQLYVTAL"
     gene            101613..102545
                     /locus_tag="VIB18_000102"
     CDS             101613..102545
                     /locus_tag="VIB18_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEQ8765145.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            102609..103334
                     /locus_tag="VIB18_000103"
     CDS             102609..103334
                     /locus_tag="VIB18_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765146.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIDGSSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            103335..104189
                     /locus_tag="VIB18_000104"
     CDS             103335..104189
                     /locus_tag="VIB18_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8765147.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(104337..105143)
                     /locus_tag="VIB18_000105"
     CDS             complement(104337..105143)
                     /locus_tag="VIB18_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ8765148.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            105360..107765
                     /locus_tag="VIB18_000106"
     CDS             105360..107765
                     /locus_tag="VIB18_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8765149.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(107835..108188)
                     /locus_tag="VIB18_000107"
     CDS             complement(107835..108188)
                     /locus_tag="VIB18_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEQ8765150.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            108432..108857
                     /gene="rplK"
                     /locus_tag="VIB18_000108"
     CDS             108432..108857
                     /gene="rplK"
                     /locus_tag="VIB18_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEQ8765151.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            108963..109652
                     /gene="rplA"
                     /locus_tag="VIB18_000109"
     CDS             108963..109652
                     /gene="rplA"
                     /locus_tag="VIB18_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEQ8765152.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            109973..110701
                     /locus_tag="VIB18_000110"
     CDS             109973..110701
                     /locus_tag="VIB18_000110"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEQ8765153.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            110730..111287
                     /gene="frr"
                     /locus_tag="VIB18_000111"
     CDS             110730..111287
                     /gene="frr"
                     /locus_tag="VIB18_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEQ8765154.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            111396..112253
                     /locus_tag="VIB18_000112"
     CDS             111396..112253
                     /locus_tag="VIB18_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8765155.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYIDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIHLDVDKKDRIWGLPAESEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            112326..112835
                     /gene="msrA"
                     /locus_tag="VIB18_000113"
     CDS             112326..112835
                     /gene="msrA"
                     /locus_tag="VIB18_000113"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEQ8765156.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            112832..113047
                     /locus_tag="VIB18_000114"
     CDS             112832..113047
                     /locus_tag="VIB18_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEQ8765157.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            113203..114372
                     /locus_tag="VIB18_000115"
     CDS             113203..114372
                     /locus_tag="VIB18_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8765158.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQPTVPMAPSATPSDVPTTPFASAKPDSSVT
                     ASSELTSSTNDVSTESSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDPTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMN
                     AGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYA
                     IDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            114687..116459
                     /locus_tag="VIB18_000116"
     CDS             114687..116459
                     /locus_tag="VIB18_000116"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEQ8765159.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKENETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQEYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDVNLM"
     gene            116618..117670
                     /locus_tag="VIB18_000117"
     CDS             116618..117670
                     /locus_tag="VIB18_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEQ8765160.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYEMSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            117716..118291
                     /locus_tag="VIB18_000118"
     CDS             117716..118291
                     /locus_tag="VIB18_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEQ8765161.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            118450..118947
                     /gene="ybeY"
                     /locus_tag="VIB18_000119"
     CDS             118450..118947
                     /gene="ybeY"
                     /locus_tag="VIB18_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEQ8765162.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            118928..119335
                     /locus_tag="VIB18_000120"
     CDS             118928..119335
                     /locus_tag="VIB18_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEQ8765163.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLIISGYAVLTGLIIFIPKIWNIFVH"
     gene            119455..120351
                     /gene="era"
                     /locus_tag="VIB18_000121"
     CDS             119455..120351
                     /gene="era"
                     /locus_tag="VIB18_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEQ8765164.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            120371..120847
                     /locus_tag="VIB18_000122"
     CDS             120371..120847
                     /locus_tag="VIB18_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8765165.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            complement(121153..121332)
                     /locus_tag="VIB18_000123"
     CDS             complement(121153..121332)
                     /locus_tag="VIB18_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765166.1"
                     /translation="MRYPHAHIILIGNHINYEEIFKNHYRVFGVIDTTSHKSLRSIRD
                     QIQLYLDELYNSNNG"
BASE COUNT        38121 a        21811 c        25460 g        35996 t
ORIGIN      
        1 ggggtaaatc tatgaaaaaa gtgtaatcat tttttgattt acagttatta tcatgtgtta
       61 actggcgact gtcctattta caagtaagtt cacaagtatg ggataaaata gtataaacta
      121 tagtaaatac tgaatagtca aagaaaaata tcggcatagg tcagaagagc tgatatgttt
      181 aatacttttt gcggatatct actgtattta aatgtatttg atatccttgt caaggatata
      241 cgtctaaaca agttcaaaac gaaatcattt gtgattatct tatcaggagt tgactcttga
      301 taagattttt gtatatcagt actgtggtac gtttagatag cttggcagtg aatttataga
      361 gtgtcaaaca acgagtgttt tgtgttacac taaccattag aagagtctat tgttgagcat
      421 atcaaggtgt tatcttttcg agttgaggta tcatatctag tatatttaac tatggtttta
      481 aatgctattt caaaaaaaat atgataaaat agaaagtact aattattttg gagatgacat
      541 gagtatcgat gattataggc cgacctatat ggtagaggct atttatgatt taagagcaaa
      601 tgatttgttg cgtcatggta ttacggctgt tttagtggat ttagataata ccttaattgc
      661 atggaataat cctgatggca caccagaggt tcgcgcttgg cttgatgaaa tgactatcgc
      721 ggatattagc gtggttgttg tttcaaataa taaacattct cgtgttgagc gtgccgtttc
      781 acgatttggt gttgacttta ttagccgtgc tttgaagcca tttgcttatg gtattgaaaa
      841 agccattgct cgttatggat ttgatcgcaa cgaggttatc atggttggag atcagctaat
      901 gactgatatc agagctagtc atagagctgg aataaaatca gttttagtca aaccacttgt
      961 tgcttctgat gcttggaata ctaaaattaa ccgctggcgt gaacgccgtg tgatggcaaa
     1021 attagaagag aaatatggta aattatcata tcaaaaagga atttaatgga agaattattt
     1081 tgtataggct gtggtatcca gattcaaact gaagataaag aaaaagctgg ttttacgcca
     1141 gctgctgctt tgaaaaaggg tatggaaaca ggagaactct attgtcagcg ctgctttaga
     1201 ttgaggcatt ataatgaaat tacagatgtc catattaccg atgatgaatt tttaagactt
     1261 cttcacgaag tgggtgatag tgatgctctt gtggttaatg tgattgatat ttttgacttt
     1321 aatggttcta ttattccagg tctatctcgc tttatttctg gtaatgatgt cttactggtt
     1381 gggaataaaa aagatatttt gccaaagtct gttaaggatg gtaaagttac tcaatggttg
     1441 accgaacgtg cacacgaaga aggtcttcgc cctttagacg ttatgttaac gagcgctcaa
     1501 aataaatatg cgattaaaga cttgattgag cgtatcaatg agttacgtaa tggtcgagat
     1561 gtttatgttg tgggggtcac taatgttggt aaatcaacct tgattaatgc gattatccaa
     1621 gagattactg gtaacaagga tgtcatcacg acgtctcgtt ttcctgggac aactcttgac
     1681 aaaattgaaa ttcctttgga tgatgggacg ttcatttttg atacaccagg aattattcat
     1741 aggcaccaga tggctcatta tttatcccct aaagagctaa aaatagtgag tcctaagaag
     1801 gaaatcaagc ctaagacgta tcaattaaac ccagaacaaa ctctcttttt aggtggtttg
     1861 tctcgctttg actttatcaa tggggagcgt caagggttta cagctttttt tgacaatcaa
     1921 ctagaattac atcgtacaaa attagctgga gcagatgctt tttatgataa gcatgttgga
     1981 actttgttaa ctcccccagg taagaaagag ttgacagcat ttcctaaatt agttcgtcat
     2041 gaatttacaa ttgatcagaa aatggatatt gttttttctg gtctaggatg gattcgtgtt
     2101 aatggtcaaa aagactcaaa agcgatagtt gctgcatggg ctcctgaagg agtcgctgtt
     2161 attgttcgta aagcgattat ttaaaaataa aaaagaagtt ggaaaaaaat gcttacaagt
     2221 aaacaaagag ctttcttaaa atctgaggct catagcttaa aaccgattgt acaaattggc
     2281 aaaaatggat taaatgacca cattaagact agtattcgtc aagctttgga tgctagagaa
     2341 ttgataaagg tcactttttt gcaaaatact gatgaagata ttcatgaagt agcagagatt
     2401 ttagaagaag aaattgggtg tgatacggtt ttgaaaattg gtcgtatctt gattctctat
     2461 aaggtttctg ctaagaaaga aaaccgcaag ttgtccccta aagttaaagc aatctagtcc
     2521 ttttatttgt ataggggctg gtcttatgag acgaggacta ttgtcgcgag aattttggag
     2581 aaagtatggc attagaattg ttgacgcctt ttacgaaggt agaattagag gaagaaaaaa
     2641 aagaaagcaa ccgcaaacag attgggattt taggagggaa ttttaatcct attcacaatg
     2701 cacaccttgt ggttgcagat caagttcgcc agcaattagg attagatcag gtgctattga
     2761 tgcctgaatg taaaccaccg catgtggatg ccaaagagac tattgatgag aagcatcgtc
     2821 tttgcatgtt ggaattggct attgaagatg ttgaagggct agctattgaa acctgtgaac
     2881 ttgaacgtca gggaatcagc tatacctatg atacgatgct ttatttgact gagcagcatc
     2941 ctgatgtcga ttattatttt attatcggag ctgatatggt tgattatttg ccaaagtggc
     3001 accgtattga tgaactggtc aaactcgttc aatttgttgg ggttcaacgt ccaaaatata
     3061 aagctggaac ctcttaccca gtcatttggg tagatcttcc tttgatggat atttcttcta
     3121 gtatgattag ggattttatt aaaaaaggtc gtcagcccaa ttatctctta cctaagcagg
     3181 ttttagacta cattactcaa gaaggtttgt atcaatgaca tatgaagatt atcttcctta
     3241 tagcaggacc gaactgttag caaaaattgc agagcagatg agccctaaac ggtttaaaca
     3301 tgtacttggc gtggaaaagg cagccttgtc cttggcagag tgttatggtt gtaacccaga
     3361 caaagcaggg ttagcagctc ttttacatga ttatgccaag gagtgccctg accaggtctt
     3421 tttagactta attgacaagt accaattatc tccagaatta gctaaatggg ataataatgt
     3481 ctggcatggt atggttggta tttataagat tcaagaagac ctagggctaa aagacaaaga
     3541 tatcttgcga gctattgaaa ttcacaccgt tggtgctgct gagatgacct tgctggataa
     3601 ggtcttatac gttgctgatt atattgaaga aggtcgcatt tttcctttgg ttgatgacgc
     3661 tagaaaaatc gcgaagctcg atttgaatca ggctgttgcc tatgaaacag tgaacactgt
     3721 cgcttattta gcctcaaaag cgcagcctat tttcccacaa actctggata cctataatgc
     3781 gttttgcagc tatttaaagg aatactaatg gataatgata tgaggaataa aatgaaaaaa
     3841 gaagaactct taaaaattgt tgtggaagca actgatgaaa agcgtgctaa agatatttta
     3901 gccttggatt tagaggggtt aactagtttg actgattatt ttgtgattgc gagtgcaaca
     3961 aatagtcgtc aattagaggc tattgcggat aatattcgtg aaaaggtaaa agaggctggt
     4021 ggagatgcta gccatgttga aggtaatagc caagcaggct gggtcttgct tgatttgacc
     4081 gatgtggtgg tacatctttt tttagaagac gagcgttacc actataatct tgaaaaattg
     4141 tggcatgaag cgcctgctgt ggctctagat gcctatttag cttaatgtta caaagagacc
     4201 ttgtcaatac gacagggttt ttgaggatga taatggaaca taattatgaa aaatttgcgt
     4261 cagtttatga tgctgtgatg gatgattctc tatatgactt gtggacagat ttttcacttc
     4321 gacatttacc aaagtctaag ggtcgaaatc gtttgttaga gttggcctgt ggaaccggta
     4381 ttcagtcagt tcgttttgct caagcaggtt ttgatgtgac tggtttagac ttaagccaag
     4441 acatgctggc tattgctaaa aagcgtgcgc aatctgctaa aaagaaaatt gattttattc
     4501 aaggtaacat gctggatttg tcacaggtgg ggcagtttga ttgtgtaacc tgctattcgg
     4561 attccatttg ctatatgcaa gacgaagttg atgttggcga tgtttttaaa gaagtttatg
     4621 atgttttagc aaacgatggc atctttattt ttgatgtgca ttcaacctat caaacggatg
     4681 agtgtttccc tggttattcc tatcatgaga atgcagatga ttttgcaatg gtttgggata
     4741 cctatgctga cgaggctcct cactctgttg ttcacgaact cactttcttt atccaagaag
     4801 acgatggacg tttttctcgc tttgatgaag tgcatgagga acgaacgtat gagttattga
     4861 cttatgatat tttgttggaa caagcagggt tcaagtcatt taaggtctat gctgattttg
     4921 aagataagga gccaactaag accagcaagc gttggttttt tgtagcatat aaatagaaga
     4981 aaaaagtagc ctttttagct ataggattta atgaattatc ttgaatgtta cttatatgaa
     5041 aagagttcat taggcattaa atgctattat caaagcttag aagtattgga gacattacga
     5101 ttgacactat gtctgaaggt tgctaccaac tttaaagaaa gcattttcta ttatacgttg
     5161 tgcttaagca tttgatttaa ctcttattag ccctataaaa gactatttag tacaatttga
     5221 ggagattcta tgaccgttac cggaattata gctgagttta atccgtttca caatggacac
     5281 aaatatttgc tagaaacagc agagggacta aaaattattg ctatgtcagg aaattttatg
     5341 caaagaggag agcctgctct tattgataaa tggattcgat cagagatggc tcttaaaaat
     5401 ggtgcggata ttgttgtgga attgcccttt ttcgtttcag ttcaatcagc agactatttt
     5461 gctcaaggag ctattgatat tctttgtcaa ttaggaattc agcaattagc atttgggaca
     5521 gaggatgtga ttgattatca aaaactgatt aaggtctatg agaaaaaatc agagcaaatg
     5581 actgcctatt tatcgacgct tgaagataca cttagctatc cacaaaaaac acaaaaaatg
     5641 tgggaaatct ttgctggagt taaattttca gggcaaacgc caaatcatat tttggggtta
     5701 agttacgcaa aggctagcgc tggaaagcat atacaactat gtcctatcaa gcgtcaaggg
     5761 gctgcttacc attcgaaaga caaaaatcat ctgctagctt ctgcaagtgc cattagacag
     5821 cacctgaatg attgggattt cataagtcat tcagtaccaa atgcaggttt acttataaac
     5881 aatccccata tgtcatggga ccattatttt tcattcttaa aatatcaaat tctgaaccat
     5941 tctgatttaa ctagtatttt tcaggtcaat gatgaattgg caagtcgtat taaaaaagcg
     6001 ataaaagtta gtcaaaatat tgaccaccta gttgacactg ttgctaccaa acgctataca
     6061 aaagctcgtg taagacgtat tttaacctac attttggtta atgctaagga acctacttta
     6121 cctaaaggaa ttcatattct agggtttacc tcaaaaggac aagcacattt aaaaaaatta
     6181 aaaaaaagca ggcctctgat tactagaatt ggagcagaaa cttgggatga gatgacacaa
     6241 aaagcagaca gcatctatca acttgggcat caggatatcc cagaacaaag ttttggaaga
     6301 atacctatta taataaaaaa tgagaggctc aattaaactc taattgagtt tttttggggg
     6361 cttgactcta acattacgtt gatggtttat acttcagtta atccaatgag gaaattttat
     6421 aacaataatt aaaaaagtca gtcaaaagat atgctttcga agaacaggct aacgttttta
     6481 caagattata tcagtaatca ttttgacaat tgtagtaatg gaatgttgcc aaaatttaga
     6541 acgttgtgtg ttatgaatga caagatttta aaggaatact aattaaacgg gaggtcgtga
     6601 accggaagct gttgtcactc aagcgccaaa atctgtctgt aacataatat tgatgtatgg
     6661 gaacgcaatt atttggtttt tattgtgatg cttaaaacga ttttatattt ctattttacc
     6721 aaagcttttc aaagtgctat aataagggag ttagagtcaa tattagtaac gttaatgttg
     6781 acaatattca ataaaatact attaaaagga gacaaaaatg ggacgtaaat gggcaaatat
     6841 tgttgctaaa aaaactgcta aagatggagc aacatcaaag gtctatgcca aatttggtgt
     6901 tgaaatttat gtggctgcca aacaaggcga gccagatcca gagttaaata cagctcttaa
     6961 atttgtcatt gatcgtgcaa agcaagcaca agtgccaaag catgttattg ataaagcgat
     7021 tgataaagct aaaggaaaca cagatgaaac tttcgtagag ggacgctatg aaggttttgg
     7081 tccaaatggt tcaatgatta ttgtggatac tttgacatca aatgttaacc gtacagcggc
     7141 aaatgtacgt acggcttacg gtaagaacgg tggcaatatg ggagcttcag gatctgtatc
     7201 ctacttattt gataaaaaag gggtcatcgt ttttgctggt gatgatgctg acagtgtctt
     7261 tgaacaatta cttgaagcgg atgtagacgt agatgatgtt gaagcagaag agggaacaat
     7321 aacagtttat accgccccaa cagatcttca taaaggtatc caagcacttc gcgataatgg
     7381 tgtagaagaa ttccaagtta ctgaacttga aatgattcct caatcagaag tagtattgga
     7441 aggtgatgac cttgaaactt ttgaaaagct tattgacgca ctcgaatcag atgatgatgt
     7501 tcaaaaagtg tatcataatg tagcagattt ttaaattgac atagaataat aaaaagagtt
     7561 gaaatctatt tcagctcttt ttaagtgatg cttttataag taagtaccag gtaacatagt
     7621 cgttgttaga agataatgaa caatagtaaa tcagtatcaa cttgatagga atcaattatt
     7681 agtgaactct aattaaaaat ggtaaactag acacaagaac aaaaaggaga gataggatga
     7741 ttaaaaaaca atatttagga agggcaacaa ttgccctagc atcaaccctt gtgctagcag
     7801 cttgtgggtc atcaaaaaaa gctgagtcag gaaatcaggg gagttctaaa gaagtcttat
     7861 ttgcaacggt tggaacaaca gctccctttt cttatgaaaa aggtggtcaa ctaactggct
     7921 acgatatcga ggtggctaaa gcagtcttta aaggatcgga tgattacaag gtgtccttta
     7981 aaaaaacaga atggtcttct atctttacag gtttggactc aggaaaatac caaatgggtg
     8041 gtaacaacat ttcctttacc aaagagcgtt cagctaagta ccttttttct tatccaatcg
     8101 gatcaacacc ttctgtttta gttgttccaa aagacagtga tatcaagagc tttgatgata
     8161 tccaagggca tacgacacaa gttgttcaag ggactacaag tgttgcacag ttagaagact
     8221 ttaataagaa acacagtgac aacccggtta ctctaaaatt caccaatgag aacattactc
     8281 aaatgttaac caatttgagt gaaggcaagg cagatttcaa gatttttgac gctccaacgg
     8341 ttaacgccat tattaaaaat caagggttag ataatctcaa aacaattgaa ctcacctcaa
     8401 cagagcaacc atttatttat tttatcttta gtcaagatca agagaaattg caaagctttg
     8461 ttaacaagcg tattaaagag ttgactgctg acggaactct tagcaagctt gccaaagagc
     8521 accttggcgg tgattacgtg ccatcagata aagagttgaa acttcctaca gctaactaaa
     8581 ccatctatta accagttatt catctagaag actggttttt ctgatcggaa acaatattat
     8641 agtttatgag gttatgttat aaaaattgca aatagcctta atcaaaatga gatgttaaag
     8701 tgctttttga gaagtgaata ttgtaagaag tatgctttgg gttttagtcc tcaaatacca
     8761 agttttttgt tgactaaaca aataaggatg gttagcatag catatagttt aaaactatgc
     8821 tatatgctag ccattatcaa tttgaaaact atatctaatt aagatacaat aatgatcgta
     8881 aacaaaatga atcgaggata acgctatgtc ttttaaaaaa tggattggaa tagtcggaat
     8941 cgctttagca tcaactgtat tagttgcttg ttctgaaaaa caagatgata aaaacacttt
     9001 aactattggg gtgatgacaa aaacagaatc tgatcaagcg agatgggata aagttgaaga
     9061 attattgaaa aaagacaata tcactttgaa gtacaaagaa tttacagatt actcgcaacc
     9121 taataaggca gttgctaatg gtgaagtcga tattaatgcc ttccaacact ataatttctt
     9181 aaataactgg aataaggaaa ataaggaaca tttggtggcc attgctgata cctatatcag
     9241 cccaattaac cttttctctg gaaccagtca agatgggaag gctaaataca aatcagtagc
     9301 tgatctgcca aatggtgctc aaattgcagt accaaatgat gcgaccaatg aaagccgtgc
     9361 cctctatgtg ctgcaatcag ctggcctcat taaattgaat gtgtctggtg atcaattagc
     9421 aaccattgcc aatatctcag agaacaaaaa gaaattagat atcaaggaat tagatgctag
     9481 ccaaacggca cgtgctttag tatctgctga tgcagctgtt gtcaataata gttacgctgt
     9541 tcctgcaaaa attgactaca aaacctctct tttcaaagaa aaagcagatg acaattcaaa
     9601 acagtggatt aacattattg caggtcaaaa agattgggaa aaattagaga aggctgatgc
     9661 tattaaaaaa ctcatcaagg cctaccaaac tgatgaggtg aagaaagtcg tggaaaaaac
     9721 ttcaaatggt atagatgtat ccgtatggta aattttagcc attgttataa caagagtgtg
     9781 gttgtgttta aaacacatgc tttcttgcat gcttgaggaa gagtttacga ttaatttacc
     9841 tttagaaagc tatttaagac cttttccctt ttaggattta gcaaccttgg gaagactatt
     9901 gcatgttatc ttaatagtca tgattatgca ggcgatgaaa acattgctat cgtagattac
     9961 tgtcgccata tcgtactaat agaggagtta ttaaaatctt atgaatgaag caataattca
    10021 attagatcat attgatatta ccttccgtca aaaaaaacgg gttatcgaag ctgttaaaga
    10081 tatcacggtt catatcaatc aaggagatat ttatggcatt gttgggtatt caggtgccgg
    10141 gaaatcaact cttgtgcgtg tgattaacct gctacaggca ccaacaaacg ggaaaatcac
    10201 tgttgatggg gatgtgacct ttgaccaggg gaaagttcag ttatcagcca atgcccttcg
    10261 ccaaaaacga cgtgatattg gcatgatctt ccaacatttc aatttgatgg cccaaaaaac
    10321 agccaaagaa aatgtagcat ttgcgctccg tcattcgtcg ttaagtaaga ctgagaaaga
    10381 acacaaagtt atcgaactgc tagaacttgt aggtttatca gagcgagcag ataactaccc
    10441 tgcccagtta tcgggtgggc aaaaacaaag ggtggctatt gcgcgtgctc tagctaacga
    10501 tccaaaaatt ttgatttcag atgaggccac atcagcacta gatccaaaaa ccactaaaca
    10561 aattttggcg ctcttgcaag aattaaaccg caaacttggc cttaccattg ttatgattac
    10621 tcatgaaatg caaattgtta aggatatttg taatcgtgtt gctgttatgc aaaatggtgt
    10681 tttgattgaa gaaggttctg tccttgatat cttttcaaat ccaaaagaag ccttgacaca
    10741 ggaatttatc acaacagcta cagggattga tgaggcttta gaaaaaatta accaacaaga
    10801 cattgttaaa catttgcctg caaatgccct tctagctcag ttgaaatatg caggaacttc
    10861 tacggatgag cctctactta atagcattta ccgtcagttt gaagtgacag ctaatatttt
    10921 gtatggcaat attgagattt tagatcatat tccagttggt gacatgattg ttgtcttgga
    10981 agggcaagct gaaaatattc ttgcggctga gaaagccttg catgaagctg gtgttgatgt
    11041 tagtatttta aagagaggag cctagatgtc acagttaatt caaacttatt tgccaaatgt
    11101 ttatgaactc ggatggtctg gagatgctgg ttggggctta gcgatttgga atactttata
    11161 catgaccatt gtgcctttta ttgttggggg tgctattggt ctcttattag gcttgttatt
    11221 agttttaaca ggaccggacg gtgttattga aaacaaaacg atttgttggg ttattgataa
    11281 agttacctct gtttttagag ccattccttt tgttattttg attgctattt tagctagctt
    11341 tacctatttg cttttaagaa caactttagg agcaacagcg gccttggtac ctttaacctt
    11401 tgcgactttt cctttttatg cccgtcaggt ccaagttgtt ttttcagaat tagacaaggg
    11461 tgttattgaa gcagcacaag cttcaggtgc tactttctgg gatattgtca aagtgtatct
    11521 cagtgaaggt ttaccagatc ttattcgtgt ttctacagtc accttaattt ctttagttgg
    11581 ggaaactgcc atggcaggag ctatcggtgc tggaggatta ggaaatgtag cgatttctta
    11641 tggttataat cgttttaaca atgatgtgac ttgggtagcg actattatta ttcttttaat
    11701 tatttttgct atccaattta ttggtgatag cttgactaga aggtttagtc ataaataaac
    11761 gaaacaacac cctaagtaaa aacttagggt gttgttgttt agatgatgtc attagctttt
    11821 cttcgtttta cttagtataa gccctattaa aaaaccaata gcagcaaata taatccatcc
    11881 cattgagaat tgccctagtg gaacagtttt ttggaaaaaa gttacaacgg cttctggtaa
    11941 atgaaataat ccagtcattt gtgatagtgt taggagtgca tcaaatatgg caggaataaa
    12001 ggttagacca attgtagttc gatagacaat aggatcatta ttgaagcatt tttgtgccaa
    12061 aacaaggaaa attaaatcga ctgttaatgg gtataaaagg aataaaacag gagctgacca
    12121 gttgataatg actgataagc caccaaaata aaagaaagct gatagtaaag taaagatagt
    12181 tgcccaagca atatgagata aagcaggcac taatttatgg aagtattcag cacttgacgt
    12241 gattaagcct gttgaagtgg ttagacaggc caggaaaatc acaacagcta gaaatgcttg
    12301 tccgatgcca cctaggtaaa aacgagaagc atgacttaag atttgaccgc cattaactgg
    12361 attaccatga agggtaaagc tgccatcaat aaaaggaaat aatgattgtg atgttgctcc
    12421 aatacgaccg acaaagatat agacaagtgc taatagcaaa atggcaatag ccccagaaat
    12481 aagtgttatt ttggtcattt ctttgtccgt cttagcgcca aattgtttgg tagcctcaat
    12541 gactaaaata gcaaaaacaa gagaagctag tgcatccata gtgccataac cttgaattaa
    12601 tcctgctata aaaggaaaat ctttaaaggc attattaaca ccgaccccag cgttaaaagc
    12661 atcaccgtaa tttccagcag gatggacaaa ggacgtgata accaaaatag aaataacaac
    12721 taacaacgtt ggcgttaaaa attttccgat attttcagct agtttactag gtttgatagc
    12781 aaggaagtag gacagaccaa aaaatagtat agcataaata actttattgg ttgtattatc
    12841 tcctaagata ggagcgatac cgactgaaaa agaagtggct cctgttcttg gaatagcaaa
    12901 aaatgggcca atagataaat acaaaatgga agaatagaag attgcatacc atttagagat
    12961 ggggcgtgcc aaactttcaa catcgcctga tccagattta gcaacagcaa tgacaccgag
    13021 taaaggcaag gagacaccag ttaaacaaaa accaatgata gaccatagaa tctgatgacc
    13081 tgagtagatg cctaaaaaag ctgggtaaat gaggtttgct gctccaaaaa atagcgcaaa
    13141 tagcatgaat ccaatgacga tatatacatt tttttgtttc atttataaat agtctttcta
    13201 ttgatactaa tccgaagatt ctaacaattt taattgtatt atgtgtcaaa ataacaacaa
    13261 aggttattat atctaagatt acttcgatag tcaatagaaa ttgactgaaa attcttagca
    13321 caaaaaatgg ttaagatatg tagctcattc gatttgacga atagatagaa ttatattatt
    13381 ataaaaaaca tgtaacttta gtaaggatgt aacgtatgaa aaaaatatat gatttatggg
    13441 ttagggttag tctaatcaaa aaaataggta tcggtgttgt aataggagtc atgttgggca
    13501 ttttggctcc tgatcttaca ggttttagta ttttaggaaa gttatttgtt ggtggtttaa
    13561 aggctatcgc acctttgctt gtatttgctt tggtttccca agccatctcc catcagaaaa
    13621 aagggaaaca gactaatatg acattaatca ttgttctgta tttatttggt acctttgcgt
    13681 cagctttagt agcagtactg acagcttatc tattcccttt gacgttagtg ttaaatacac
    13741 ctgtaaatac agaattatca ccacctcaag gtgttgctga agtttttcag tcacttctat
    13801 taaaattagt ggataatccg atcaatgctt tagctactgc caattatatt ggtgtgctat
    13861 catgggcaat tatttttgga ctagcattaa aggctgcaag tcaagaaaca aagcatctta
    13921 taaaaacagc ggcagaagtt acttcacaaa tagttgtttg gatcatcaat ctggcaccta
    13981 ttgggattat gagtctggtg ttcactacga tttctgaaaa cggtgttgga atcttatctg
    14041 attatgcttt tttgatacta gttttagtag gaacaatggt ttttgtcgcc ttagtggtta
    14101 atccacttat tgcggttttg attacacgac aaaatcctta tccccttgtc ttgagatgtt
    14161 tacgtgagtc aggtcttaca gcatttttca cacgaagttc tgcagccaat attccagtca
    14221 atatgcaatt atgccaaaaa attggattga gtaaagatac ttattcagtg tcaattccac
    14281 ttggagcaac tattaatatg ggtggggcag caattaccat caatgtccta acgcttgctg
    14341 ctgtacacac ttttggtatt cctattgatt ttctaacagc cctcttactt agcgttgttg
    14401 ctgctgtctc tgcttgtggt gcttctggtg ttgctggggg atcgttgtta cttattcctg
    14461 tagcatgtag tttgtttggc atttcaaatg atcttgcgat gcaggtggtt ggtgttggtt
    14521 ttattgttgg tgttatccag gattcttgtg agacagcctt aaattcgtca accgatgttc
    14581 tttttacagc tattgctgaa aatgcttttt ggaaacgtaa aaaagcctag ctaggtttaa
    14641 catagtaaaa aacatccttg gaaaacgcca aggatgtttt tttattattt aagatagcca
    14701 agataatcaa atttttcaaa ggtgtggtca ttagcgatgg ccacaatgat agtattcggt
    14761 tctaaaggtt cgaaaggttt gacattggta tctaaggttt taacttcttt ttgacgcatg
    14821 ccaatcacat ttaactcata tttacgacga acatctaact ctgaaagaga ttgtccttcc
    14881 cagcttttag gaatgacaaa ttcaatcatc gaaataccat gttccaaata gatgatgctt
    14941 tcgatatgac gtcttaacag atttgaagct acacgttttc cagaatcacg ttcaggggtg
    15001 atgactttag ttgctccgat gccatataga acttcttcaa aaattttatt tttagccttg
    15061 gcaataatgg ttggaacacc gagtttttta cagtgcatga ctgcaagaac agaagattcc
    15121 aagttattcc ctgaagcgat aacgacagta tcacaatgtt caatccctac agctaataga
    15181 aattctttgt cagtaatatc tccaacagcg gctttagtga ccaagtcggc cacctcttta
    15241 acatgacttt ctctgatatc aatagcaata acgtcttgat caaaattact taattctctg
    15301 gcaacagtac ggccaaaaat accaaggcca agaacgccga cagttttacg ttttaacatg
    15361 ttttctcctt aacccactaa aatatcagta gtggcatatt gaatggtttt ttcttttcgt
    15421 tgaatcagac tgatgaggac agtaattggg ccaacgcggc cgacgaacat caagacaatg
    15481 acaataagac gtccagcagt agacaattgt ggtgtcaaat ccatagatac cccaactgtc
    15541 gcgatggcag aaatagattc aaataagagt ggtataggag cgatatgagg ctccacgcta
    15601 agtaataaaa taaaacctat cataagaact gcaaaaaaga agataagaac tgtcatggtc
    15661 tgcttaattg tcttatttgc gataattcgg ttacgaaagg taacttctga ttgccctgaa
    15721 agttccgctt taaagagtaa gaaagtaatg gcagcagtcg tcactttaat accaccagct
    15781 gttccaccag gagcaccacc aataaccatt tgaatcatat aaagaatgtt agtcggtgct
    15841 agggtatcgt tataagagat tgttgcaaag ccagctgttc tcatagtgac tgtttgaaaa
    15901 aatgaaacca taagttgctg atgtaaacta aaattggcaa tggttttgct gttatctttt
    15961 tctaaaaacc aggttaagaa ggttccaaga aaaagaataa cagctgtggt ttgtagtact
    16021 agacgagact gattggataa tttacgaaaa gttgccccat aacaatgagg tctttcaaaa
    16081 aagtattttt taaaagctac tcctaaatca acccaaaccg caaaaccaag tccaccagag
    16141 ataatcaaga acgtaatgat aacatttaat gtaggattta acataaagtc ttttaaacta
    16201 gaagatccta aattgtcaaa accagcgtta caaaacgccg acacagctaa aaaaatacta
    16261 ttgaagatac catttttcca cccgaagcgg gggatgaagt caatcatgat aactatcgca
    16321 gcaaaggctt ctagactaaa ggttacttta taagcaaaaa aaaggtagtg ctttaaatct
    16381 ttgctatcac ctcgatttaa cgctgattgg agcaaggttt gatcgctcaa tcgcattttt
    16441 cgcttgaggg caaaagtact cacagctatt aacgtcacca agccaagacc accaatctgc
    16501 attagtgcca tagcaatggt ttgtccgata ccgttataca cttcagcgac gggaacaaca
    16561 gaaagtccag tcacacaaac catggaaacc acattaaaga aatgatcaag atagacggta
    16621 ttaggaccat tttgataatg ggtaaagggc atggataaca agagagtccc aatcagaatc
    16681 acaatggcaa aactaaaggt taagcgctgt gtgactgaaa gagatttgat aaaagagcgt
    16741 ttcatgtttc ctccagacat aatatctcct actataataa caaaaataag ttaaaaaagc
    16801 taagtttcat cttagccttt ggtactattt atagaggttt tttgttaggc aagccagctt
    16861 ttcttggata cttgttaggt gtttcctttt tcttttcaac aatggtgatg aagcgagaat
    16921 ctccatttgg caattggtag ctatggtttt taatgacttt accaaaaaga agacaaagag
    16981 cattcttagc ttcttctaac tcttggtcag cagcttgtgc ctttaaggcg attaattttc
    17041 ctccaatttt taaaaagggg atggttaatt cagatagaac ctgcatccga gcaaccgctc
    17101 tggcagtaac gacatcaaat tgacctcgaa aggccttgtc ctgtccgaaa tcttctgctc
    17161 taccatgaaa aaaatggaca ttttccaagc ccaattcctg agcaaggagt gtcagaaaag
    17221 aaatccgctt attaagagaa tcaataatgg taacctcaag gtttgggaaa agaattttca
    17281 tgggtaggct aggaaaacca gctccagctc caatgtccaa taatttgatt ggttcattag
    17341 ctaaaaagcc ctgtaaaata ggagcgatgg aatcataaaa atgcttgagg taaacttcat
    17401 tttcttctgt aatagctgtt aaattaattt tagtgttcca ttccactagt aatttgaagt
    17461 aggtgtcaaa ttgttctttt tgtttcgatg ataaggaaaa accatcttcc tctagtgttc
    17521 ggtaaaagtc ttggggtgtc attagtgtcc tctgtttttg atagttgtta ccattttatc
    17581 ataaaatagc ccataacaaa atccaataaa tcatcagaaa taacacctca ttacttgcta
    17641 ttagcctaga aattgctata attgagacac aaagattaaa ggagacccac tatgccaaca
    17701 gttttgatta tcttagtcgt tttaggagtg cttgcgctat ggttaatgat tagttacaat
    17761 agtctggtta aatctcggat gcacacaaaa gaagcttgga gtcagattga tgtgcaatta
    17821 aagcgtcgta atgacttgat tccaaatctt attgaaaccg taaagggata tgctagctac
    17881 gagcaaaaga catttgaaaa aatcactgat ttgcgtgcgc gtgttgcgaa tgcttcaact
    17941 cctcaagaaa ccatggcggc ttctaacgaa ttgagtaaac aagtgaccag tttgtttgcc
    18001 gttgctgaaa attacccaga cttaaaagct aacgaaaact tcttgaaatt acaagaagag
    18061 ttgaccaata cggaaaataa aatctcatat tctcgtcaac tctataattc aacaacgtct
    18121 aattacaacc ttcaattaga atctttccca agcaatatcg ctggtaaatt atttggtttt
    18181 aaaccaagtg aattcttaca aacaccagaa gctgaaaaag aagttccaaa agttgaattt
    18241 aacttttaaa tatgaaatta tcatctagta ggcaatcata agagaaagga gaattatgct
    18301 ttatcaacag atttcacaaa ataagcaacg aacagttgtt ttattagttg ttttcttcgc
    18361 tctcttagca cttattggag cttcagcagg ctatctgctg ttagataatt atgccatggg
    18421 cttggttctt gctcttgtca ttgggatgat ttatgctacc agtatgattt ttcaatccac
    18481 cagtcttgta atgagtatga acaatgctag agaagttaca gaaaaagagg ctccaggctt
    18541 cttccatatt gtcgaggata tggctatggt ggcccagatt ccgatgccga gagtttttat
    18601 tattgaagat ccttctttaa atgcttttgc gacaggatct agccctcaaa atgctgctgt
    18661 tgcagcaacg acaggtttac ttgaagtcat gaatcgtgaa gaacttgaag gtgttatcgg
    18721 ccatgaaatt agccacatcc gaaattatga tatccgtatt tcgactattg ctgtagcttt
    18781 ggcgagtgct gttaccgtta tttctagtat cggtgggcgt atgctatggt atggtggcgg
    18841 ttctcgcagg caaagagatg acggagatga tgatgtttta agaatcatta cattactttt
    18901 gtcgttatta tctttgcttt tagcgcccct agtagcaagt ttgattcagt tggctatttc
    18961 tcgtcaaaga gaatatctag ctgatgctag ttctgttgaa ctaacaagaa atccccaagg
    19021 tatgattaag gctcttgaaa aattgcagtt atctcagcca atgaagcatc ctgttgatga
    19081 tgctagtgcg gccttgtata ttaatgagcc tcgcaaaaaa aggagcttca gttcattatt
    19141 cagcacccat cctcctattg aggagaggat tgaaaggtta aaaaacatgt gagcgtttgg
    19201 ggtttttgct caagcctcac ttttttatgt ctttgggcag ataatctaaa atggcaggaa
    19261 ttatcaaaaa tatctgaaca aaaagaaaaa aatgagtgaa acaatggtta aaaatagaat
    19321 gatttaaatc ttaaaattaa aaaacgtcag aaaataaatg aaaaactatt gacaaatctt
    19381 ttagatagta gtaaaaataa atgagagttt tattaggaga agatgatgtt agctatttcc
    19441 gaaatcagaa aacacccaga cggtctctcg tttgatcgtt tatgtgatgt caaaagtatg
    19501 ttacttgagc gtgaccaaca gattattgac ataaaggcag ttaaagctgt cggtaatgtt
    19561 cgctatgata aggggcttta tctgttagat tatcaattga gttacgaagt gatattaccg
    19621 tctagccgtt ctatggttcc ggtctgttta agtgaagtcc aacacattca agaattattt
    19681 atagaggcga cagatttagc tgataagaaa gagttggttg aagacaatct ggtattagtt
    19741 ttagacaaag acgctattaa cctcgaagaa agtattgtgg ataatatctt acttgctatt
    19801 ccgctacagg tcttgacaga ggaagaaaag aaatcaaaag agttgccagc aggtcaaaat
    19861 tgggcagttt tgacagaaga agactaccag tgtctaaaag aagaaaagca aaaagaaaat
    19921 aatccttttg ctagcttgca agggttgttt gatgaataaa actgaatatt aaagatgtct
    19981 gtaattttta tttgaaaaaa cagctattct ttgatatact ctttagagaa tatggttact
    20041 tatctaaagt agaaggtatt ttgaccatag agggcaaaga aggtaatgac tattagatgc
    20101 ttcatatttt attcgctaga agactatttg accattagaa ctgaaatagt ctaggatatg
    20161 agatgaattt catagttttc tttctgggag aaaaagatag attaagagga taagggttgg
    20221 tataaatgac aaagaaaatt ttaattattg aagatgaaaa gaatctggct agattcgttt
    20281 ctcttgagct gcaacatgag ggttatgaag tcattgttga ggtcaatggt cgtgaagggt
    20341 tagaaactgc tttggaaaaa gagtttgatt taatcctgct tgacttaatg ttaccagaga
    20401 tggatggttt tgaagtgacc cgtcgtttgc aaaccgaaaa aacaacgtat atcatgatga
    20461 tgactgcgcg tgattctatt atggatgtgg ttgcaggttt agaccgcggt gcagacgact
    20521 atattgttaa accgtttgcc attgaagaac tacttgcccg tattcgtgct attttccgcc
    20581 gtcaagatat tgaatctgag aagaaagtgc ctagtcaagg catttatcga gatctagttt
    20641 taaatccaca aaaccgttca gttaatcgtg gcgacgatga gatttctctc actaaacgtg
    20701 aatatgattt gcttaatatt ttgatgacta atatgaatcg tgtcatgaca cgtgaagaat
    20761 tattgtcaaa tgtttggaaa tatgatgaag ccgttgagac taatgttgta gatgtctata
    20821 ttcgttatct ccgcggcaaa attgacattc caggcaagga atcttatatc caaacagtgc
    20881 gtggcatggg atacgttatt cgtgagaaat aagtcatatg gaaaatcaga aacaaaaaca
    20941 gaagaaatat aaaaattcgt taccaaaacg actatctaat atcttttttg ttcttttttt
    21001 ctgcattttc tctgccttta cactgattgc ctatagttca acaaactatt tcttattgaa
    21061 gaaagaaaag cagtcagtct ttcaagctgt aaatattgtt agagttcgtc tttctgaggt
    21121 ggactctaat tttacattag agaacttagc agaagttttg tacaaaaacg ataaaacaca
    21181 tctgagaatt gatgacagaa agggcagtcg agtcattagg agtgagcgcg atatcacaaa
    21241 tactctagat gcgaatcaag atatttatgt ctataacatt gataaacaga tgatttttac
    21301 cacagataac gaagaatcat ctcctggctt gcatggtcct atcggtcgtg tgtatcacga
    21361 ccatatcgaa gatcagtatc gtgggttttc catgacacaa aaggtatatt ctaatcggac
    21421 tggaaaattt gtgggctatg ttcaagtctt tcatgattta ggcaattatt atgtcattag
    21481 agcaagactg ctgttttggc tactagttgt tgagttattt ggcacaagct tagcctattt
    21541 aatcatctta attactacgc ggcgcttttt gaagccttta cacaatttac atgaagtgat
    21601 gcgtaatatc tctgaaaatc ctaataattt aaacctgcgc tcagatattt cgtcaggaga
    21661 tgaaatcgaa gaattgtctg ttatctttga caatatgtta gacaaattgg agacacatac
    21721 taagttgcaa tcacgtttta ttagtgatgt cagccatgaa ttacgaacac cggttgcgat
    21781 tattaaaggg catattggtc tcttacaacg ttggggtaaa gatgacagtg atattcttga
    21841 agaaagcttg acagcaacag cgcatgaggc tgaccgtatg gcaatcatga ttaatgatat
    21901 gttagacatg attcgcgtac aaggctcatt tgagggacat caaaatgata tgacagtttt
    21961 ggaagattct attgaaactg ttgttggtaa ttttagagtt ttaagagaag attttatctt
    22021 tacatggcag tcagaaaatc caaaaacgat agcccgtatt tataaaaatc attttgagca
    22081 ggctttgatg attctgattg acaatgctgt gaagtattcc cgtaaagaaa agaaaatcgc
    22141 gattaacctt tcagtgactg gcaaacaaga agctattgtt agagttcaag ataaaggcga
    22201 aggaatttct aaagaagata ttgaacatat ctttgaacgc ttttatagaa cggataaatc
    22261 acgtaatcga acaagtaccc aggctggatt agggattggc ttgtctattc tcaagcaaat
    22321 tgtagatggg tatcatttac agatgaaggt tgaaagtgaa ttaaatgaag gttcagtgtt
    22381 tatcttacat attcctttgg cccagtctaa agagagttag agtagcttaa ggcattgtta
    22441 atgtgacagg tatagtatgt aatcattaga taatagtagc agtcttttgc cataactggt
    22501 tagaagctga tgctattttt ttagcaatga tggatgacat gaaagaaata ctgtcaatcg
    22561 cgatgccttt tgttatcctt gagaatatgg taaaatagtg tattagatta atttgataga
    22621 attggggtgt ttgcgtgcgt tgtccaaaat gtaattacca taaatcgagt gttgttgaca
    22681 gtagacaagc tgaagacggc aacaccattc gtcgtcgaag agaatgtgaa cagtgtcata
    22741 ctcgctttac tacctttgag cgtgttgaag aactcccttt attagtcatc aaaaaagatg
    22801 gcacacgaga gcaattttct agagataaaa tattaaatgg ggttgtccaa agtgcgcaaa
    22861 aacgacctgt ctcgagcaca gatattgaaa atgtcatttc tcgtattgaa caagaagttc
    22921 gaacaaccta cgaaaatgaa gtgtcaagta ctgctattgg taatttagtg atggatgagt
    22981 tggccgaact tgatgaaatc acatatgtac gctttgctag tgtctacaag agcttcaagg
    23041 acgttgatga aatcgaagaa cttttgcaac aaattacgaa tcgcgtacgc ggaaagaaaa
    23101 aacgtttaaa taatgatgaa accaattgat acttttacat atctaaaacg caacaaagta
    23161 actcttgatt cggtgacttt aatacagttg tactttccaa ttattggaag tgacgcagtc
    23221 tctatctatc aatactttat tcactttttt gacgatggtt tacaacgtca taaattcagc
    23281 gatattttaa atcacctaca gtttggtatg aaacgttttg aagatgctct tgccatattg
    23341 acagcaatgg aattagtgag tgtgtatcag ctatcagata catatctcat tacgttgcac
    23401 cagccgctta gccgtgactt gttttttcaa catccagctt attctcgatt attagaacaa
    23461 aagattggag aggtagctgt ctctgagttg cagataactg tcccaagtca agcaagaaat
    23521 atttctaagc gattttcgga tatttttggg gtgcaaggaa atttgacgaa cgtacctcaa
    23581 aagccacaaa agaattttga cctttcaagt ttccagcaat taatggttcg tgatgggtta
    23641 caatttgaag ataatcaaaa agatatcatt agcctttaca gtattgctga acagtatgat
    23701 atgacgtggt ttgatactta tcaaatagct aaggcgacgg ctgttaatgg aaaaattcga
    23761 cctgaacgct tattggctaa aaaaaatcaa agcatgacaa aaccaagcaa agaaaatttt
    23821 tcacaggctg agcaaattat tttgcgagaa gcaaagcaag acagtgcttt agtctttttg
    23881 gaaaaaatta aaaaggctag acgtgcaacg attactaagg atgaacgcat tttattgcaa
    23941 acattggcca aaatgaattt tcttgatgat gttatcaatg tcatggtgct ttataccttt
    24001 aataagacaa aatctgctaa tttacagaag agttatgtct taaaaatggc caatgatttc
    24061 gcctaccaaa aggtgtcaac ggctgaagaa gctatagtgg ttttgcgagc cttcacggat
    24121 cgtcaaagtc gtcggcaatc aaaagtaaaa acaagtcaaa gtaatgtgcc taagtggagc
    24181 aatcctgatt accaagagac aacaagtcaa gaagagcagg cgaaactaga tcagttcaaa
    24241 caggctgctt tgaagaggtt agaaaaccta ggaaaagggg gtgactagat ggaaaagatt
    24301 ggagaaacca tggcgaaatt gggtcaaaac actcgtgtta atagcgacca gttgattcaa
    24361 accattttag cggatcctga agtagcaagc ttcatcagtc aacatcactt atctcaagag
    24421 caaattaacc ttagcttatc taagttcaat caatttttgg tggaacgcca gaagtatcaa
    24481 ctcaaagatc cctcttatat tgctaagggc tatcagccta ttctagctat gaatgagggc
    24541 tacgctgatg tgtcttattt ggaaaccaaa gaattggtag aagctcaaaa acaggcagct
    24601 atctctgaac ggattcaact ggttagtttg ccaaaatcct atcgccatat tcatttatca
    24661 gatattgatg ttaataatgc gagccgtatg gaagccttct ctgctatttt agattttgtg
    24721 gaacaatacc catcagcaga gcaaaaaggc ttatatttgt acggagatat gggaattggc
    24781 aagtcttact tgttggctgc tatggcccat gaattgtctg agaaaaaagg tgtgtcaacg
    24841 acccttctac attttccgag ctttgccatt gatgtaaaaa atgccatttc aaacggctct
    24901 gttaaagaag aaatcgatgc ggtcaaaaat gtaccagtgc tcattttaga tgatattggt
    24961 gcagagcaag ccacttcttg ggtccgtgat gaggtgttgc aggtgatttt acaataccgt
    25021 atgttagagg aattgccaac cttctttacc tctaattaca gctttgcgga tttggagcga
    25081 aaatgggcaa ccatcaaagg aagtgacgaa acttggcagg ccaaacgtgt catggaacgc
    25141 gtgcgttatt tggctagaga gtttcattta gaaggggcta accgccgtta agtttgagat
    25201 agcaatcaag aagaatagct acacgtatga gtgagtgaaa gaaaaggaga atcatggttt
    25261 tacctaccgt tgccattgtg ggccgtccaa atgtgggcaa gtccacctta tttaatcgaa
    25321 tcgcaggaga gcgcatttca attgtagaag acgttgaagg ggttactcgt gaccgtattt
    25381 atgctactgg ggagtggctt aaccgccaat tctcattgat tgatacaggt ggtattgatg
    25441 acgttgatgc cccgtttatg gagcaaatca agcaccaggc tcaaattgcc atggaagaag
    25501 ctgatgttat cgtttttgtt gtttctggta aagaaggggt gaccgacgct gacgaatatg
    25561 tgtctaaaat tctgtatcga accaataccc cagtcatttt agccgttaat aaggttgata
    25621 atcctgaaat gcgtaatgac atttatgatt tttattcact tggtttgggt gatccttatc
    25681 cagtttcttc tgttcatggt atcggaacag gggatgtctt agatgcgatc gttgaaaact
    25741 tgccagtaga agaggctgaa gaaaatgatg atattattcg cttcagttta atcggtcgtc
    25801 ctaatgttgg aaaatctagc ttgattaatg ctattttagg tgaggatcgc gttattgcta
    25861 gtcctgtcgc agggacaaca cgtgatgcca ttgacacgca ttttacggat gctgacggtc
    25921 aagaatttac catgattgac acggctggaa tgcgcaaatc tggcaagatt tacgaaaata
    25981 cagagaaata ttctgtcatg cgtgccatgc gtgccattga ccgctccgat gtggtcttga
    26041 tggttatcaa tgctgaagaa ggtatccgtg aatacgacaa gcgtatcgct ggctttgcac
    26101 acgaagctgg taaaggaatg attatcgtgg ttaacaaatg ggataccatt gacaaggata
    26161 atcataccgt tgctaagtgg gaagccgata ttcgtgacca attccaattt ttgacatacg
    26221 ctccgattat ttttgtgtca gctttgacga agcagcgcct caacaaattg cctgacttga
    26281 ttaaacgtat cagcgagagt cagaataaac gtatcccatc tgctgtcctc aatgatgtta
    26341 tcatggatgc tattgccatt aatccaacgc caacggataa gggtaaacgt ttgaaaattt
    26401 tctatgccac tcaagtgtca gtaaagccac caacatttgt cgtctttgtt aacgaggaag
    26461 aattgatgca cttctcttat ctacgcttct tggaaaacca gattcgcgca gcctttacct
    26521 ttgaagggac accgattcat ctgattgctc gcaaacggaa ataagaaatg aacatcaact
    26581 aaaatgctga cctaagaaat aatctcatca ttgataagga ctgtgttgtg tatgttacag
    26641 gagacagtcc tttttataat acctttaagg gtgtagacgg aagattagta gcaaacaaag
    26701 aaaaaggatt ttgacaagaa atatcagtcg gtttttgcta taatgaaagg ataagcaaaa
    26761 aggtggaaaa atgatggcta gattaattcc aggacgagta aggaatgaag gtattaagct
    26821 ttatgagcaa ggtttagtct cattccaaga tgataataaa ggcattcttc aaatagaagt
    26881 ggagacttat caggttcaat atggagcaga tgatgaggat atcacttgtc aatgcgacac
    26941 atttcatatg aaacattatt gcaagcatat tgcagcagtc gagtattttt taaaaaatga
    27001 tcaaaaaggt aagctttttt taaaacagtt aacaaatcaa acaaaaatca aagaaacaac
    27061 aaagaaaatg acatcttttg gtagtctctt tttagatagc ttagccatga atgaagatga
    27121 ttctgttaaa tacaggctgt ctgctcttgg tagtcgaagc cctttttcgt cagattactg
    27181 gtggagtctg aaaatcaatc gtttaccaga tgatcgttct tatgtgattc gagatattaa
    27241 aggctttttg cagcttatta aaaaagaagg cttttatcag attggaaaaa attattttga
    27301 acaactttca tggctgcagt ttgacccatc cagtcaagac cttattgagt ttttatggcg
    27361 cttagcatct ggtactgaca aaggggacaa cgagaacatt tttccaaatc atgcaaggca
    27421 tttgcgatta cctagtggtt tttttgaaga aggcattcac tatttgacgt cactttatga
    27481 ctttactttt gaggggcctt ctcaaactta tcatcatctt tttgtccgtt ctttggaagc
    27541 agaggcaggc ctttatgagt ttaaagtgga agtgcatcgc aaatctattg aattgcaaat
    27601 tgctgaaaaa aatgtgcaat acctctttga taatgactat cttctttatc aagatacctt
    27661 ttatcacttg acgttaaagc aacgaaaaat ggttcaggct attcgtagtc tgcccattga
    27721 ggccgacttg gctaaacata ttcattttga tttggatgat catgcgaaat tagctgcaag
    27781 cttatcagat tttaaacaga tcggtctagt agaggctcct aaaagctttg ctattagaga
    27841 ctttgaggtg acttttcaat ttgatttgtt aaatcgagat gaaatcagtt gtcagcttat
    27901 gtttgattat ggcaattacc aagttagtga caaagcaagt ttagaagcac ttccttttgc
    27961 tagtcattta aaaaaagaag aaaaaatcaa tcgttcttta cttgcttttg gcttctcgcc
    28021 acaattttac tcaaaaaagc gactaacaag tgcaaaagag ctctatactt tttttgaaga
    28081 aacagttcca tgttttgagc gcttaggtaa tgttgcgttg agtacagcta tccaagcatt
    28141 acaagtgaaa gaaatgccca agatcgctat taaacgtaat caggggttac tagacatctc
    28201 gtttgatttt tcaaccatta ttgaaaatga tattgatcaa gctgttacag ctctttttca
    28261 aaataatcct tattttgtga gtcaaacagg tcaattagtg gtttttgatg atgaaactca
    28321 aaaagttagc aaaagtttac aagaattaag agcaagacag ctaaaaaatg gtcacttgca
    28381 actggatggc attagagctc tacaagtatc caaacttttt gaaggcatga catctgttca
    28441 tttttcaaag gaattagaag agttagccta tcatttgcag catcctgaaa ctttttcaat
    28501 aaaaccgtta ccagttaagg ctcaaatgcg agattatcaa cgcaacggtg ttcagtggtt
    28561 atcaatgctc aatcattatg gctttggtgg cattttagca gatgacatgg gacttggaaa
    28621 aactctccag acacttgctt ttttagctag tcacctgaaa tcagatagta aagtgctcat
    28681 tttatctcca tctagtctta tctataattg gtttgatgaa tgtcaaaaat tcacacctca
    28741 gctagatgtt gtggtttctt acggacttaa acaaatcaga gatcaaatca tcgaagaagg
    28801 tcatcaaata accataacca gctattcctc ctttagacag gattttgaga cctatcaagc
    28861 gtttcactac gattatctta tcttagatga agctcaagtg ataaaaaatg cacaaactaa
    28921 gatttcacac tgtttacgtt cgtttaatac agccaattgt tttgcgcttt cgggcactcc
    28981 tattgaaaat aaaatgcttg aaatttggtc cattttccaa attgttttgc cagggttgct
    29041 accgactaaa aaagagtttt taaaattaac agctgagcaa gtatcgcgct atatcaaacc
    29101 ctttgtgatg cgtcgtaaaa aagaagatgt cctaccagaa ttacctgatt taattgaaac
    29161 taattattca aacgagatga cagatgaaca aaaagctatt tacttagcgc agttaaggca
    29221 gatgcaagat caaattcgaa attctagtga tgtggatatt agccgtcaaa aaattgagat
    29281 tttatctggt atcactcgat tgaggcaaat ctgtgacact ccaagtctct ttatgaatta
    29341 ccaaggcaaa agtggtaagc tagatagttt gcgaatctta ttgacacaaa ttaaagaaaa
    29401 tggtcatcgg gctttgattt tttctcaatt tagagggatg ctggacttgg ccaagcaaga
    29461 gatgactgct ctaggattga cctcttatca aatgacggga tctacccctg ccaatgaacg
    29521 tcaagaaatg actagagcct ttaataacgg ttccaaggat gcttttttga tttccctcaa
    29581 ggcaggtgga gttggaatca accttacggg agcagacaca gtgattttaa tcgatttatg
    29641 gtggaatcct gctgttgaaa tgcaggcaat cagtcgcgcc taccgtattg gtcaaaaaga
    29701 aaacgttgaa gtatatcgct taatcactcg agggacgatt gaagaaaaga ttttagagct
    29761 tcaagaaagt aagcgcaatt tggtgactac agttttggat ggcaatgaaa gccgagcaag
    29821 tatgtccatt gaagaaataa aagaaatttt ggggctaaac actcattaat cttccttgat
    29881 tttagtgaca ttaaaaaccc tttaaagaag atgacaccaa aagcacctta tataacctcg
    29941 ttaaaacgct tcttttgaaa tatctttatt gatatagcga ttgtcatttg ctagtaatga
    30001 ttaaaacatt tagaaaaaga cacgtcatag aatcatcaag gaatgctttg aaaaataaca
    30061 gtatttaagt tataatagag gatgctacaa gaagggagaa tcaaaaaagg atggtaaaaa
    30121 atcagtttcc tttagttgca gatggcattg ctattagtga tccagcaaag caaatggctc
    30181 tgtatgaaaa tgaagatctc attaccaaca tccgtggcta ttaccaggac aaggagtatg
    30241 atgatattgc tagaaatgag gagtttactg ctaaagcaac ttctcggcag gccccttcta
    30301 gtaagcgctt ttgtagcgat gatgaaaaac accattatgt caaagaggcg cgtcaaaaag
    30361 caaagcaaga tctcaaggaa aaaagacagg cttatcttgc caaagaaatg gcctatgttc
    30421 ctaaacaggt ttctaaaaag caacagcctg cggattcttc tccttctcaa aagcaagcaa
    30481 caacagaaat gagtcgtttt acaaaaaaac ttcatcaaga caactatatt ttagctgagt
    30541 tgccaaaaga atataaagag ccaaaaaatc ttcctcaaca aggaactaca aaaaaaaata
    30601 attacgattt tttaaaatcc agtcaaattt acaataataa agaaatgaga caacaacgag
    30661 aaaaaacaat tgcgcaagag cttaatctta gtaggtttga ggatcttcct taataaatct
    30721 actcagcgta tgcagatgac aaaggagtta agatgtcaaa aacgtatcat tttatcggaa
    30781 ttaaagggtc aggaatgagt gccttggccc ttatgttgca tcaaatgggg cataaggtgc
    30841 aaggtagtga tgttgaaaaa tactatttca ctcaaagagg attggaacaa gcgggcatca
    30901 ctatcttacc ttttagtgag gacaacatta cgccagatat ggaacttatc gttgggaatg
    30961 cctttcgtga aaacaacaaa gaagtggcct atgctttgag acaccagatt cctttcaaac
    31021 gttatcatga ctttttaggt gattttatga aatcatttat cagttttgca gtagcaggtg
    31081 ctcatggtaa aacttctaca acgggtttat tgtcacatgt cttgaaaaat atcacagaca
    31141 catcttattt aattggtgat ggtactgggc gtggatctgc taatgcacag tattttgttt
    31201 ttgaatcaga cgaatacgaa cgccatttta tgccttatca cccagaatac tctatcatta
    31261 ctaatattga ttttgaccat cctgattatt tcacaggaat tgctgatgtg cgaaacgctt
    31321 tcaacgatta tgctaagcag gtcaagaaag ctttgtttgt ttatggtgaa gatgacgaac
    31381 taaaaaagat cgaagcacct gcacctattt actattatgg ttttgaagag ggcaatgatt
    31441 ttatcgctta cgacattacg cgtactacga acggatcgga ctttaaggta aaacaccaag
    31501 gagaggtcat tggtcagttt cacgtacctg cttatggaaa acataacatt ttaaacgcta
    31561 cagcagtaat tgcaaacttg tttgtagccg gcattgatat ggctctagtg gcagaccatc
    31621 ttaaaacttt ttcaggtgtg aaacgtcgtt ttacagagaa aattatcaat gacactatta
    31681 ttattgatga ctttgctcat catccaaccg aaattgtggc aacaattgat gcggctagac
    31741 aaaaataccc aagtaaagaa attgtagcaa tattccagcc acatactttt actcgcacta
    31801 ttgccttatt agaggatttt gcttgtgctt taaatgaagc tgacagtgtt tatttagccc
    31861 agatttatgg ttctgcacgt gaagtagata aaggtgaagt taaggttgaa gatttggctg
    31921 ctaagattat caaaccatca caagtagtaa cggtggaaaa tgtctctcct cttcttgatc
    31981 acgataatgc tgtttatgtt tttatgggag ctggagatat tcagctatat gaacattctt
    32041 ttgaggaatt acttgcaaat ttaactaaaa ataaccaata acatgtcctg ccttaggcag
    32101 gttttctcat tctaaaggag tttgatatgt tgattagaca ggttcaagga tccgatttgg
    32161 aagttattgc taccattgaa agtgacaatt tttcaccaca agaagcaacg acaagagcag
    32221 ttcttgaaga gcgcatacgg ctgataccag atactttttt agtggcactt atcgatcagg
    32281 aaattgttgg ctatatcgaa ggtccagttg tcactactcc tattttggag gattctttgt
    32341 tccacggggt gactaaaaat cctaaaactg gaggctatat tgctattact agtttgtcca
    32401 tagctaaaca ttttcagcaa caaggggttg ggacagcttt gttggcggca ctaaaagatt
    32461 tagtagtagc gcagcaaaga acaggtctta ttttgacttg tcatgattac ttgatttcct
    32521 attatgaaat gaatgggttt attaaccaag gaatttcaga ttctcaacat ggtggaaccc
    32581 tttggtacca aatgatttgg aaactttaga atcacagctg attcaactgt tggtttgtta
    32641 aaaataagta acaaatgcat catttaattg caattaggat acttttaagt tataatggcg
    32701 gttgattata tttaggagga ttggctttga ccgattttaa ggataaagac caacaagatc
    32761 agcagcgaag ctttaaagag cagattcttg ctgagttgga aaaagcaaat caaatcagaa
    32821 aagaaaaaga ggaagaactt tttcaaaaag agttggaagc taaagaagca gctaggagaa
    32881 cggcccagct atatgctgaa tataaaagac aagatgcttt tcaaaaagag tctatagcac
    32941 ataacaataa gacagccaaa cactttcaag ctataaaaga tgcggtaatg acttcagaag
    33001 cgattaaacc gactttactt tctgaaaaag aaaactcatc tttaaaaacg acaagtaaga
    33061 gagtcgtgca ggcaaatgag cttcaagaga ctgcctctaa agaatctcaa gtaccgttaa
    33121 ctattgagaa aggtcattca gtgagacgaa aattaagcaa acgccaacag actgagcgag
    33181 ctgctaaaaa gatttcaacc gttttgatta gctctattat tataaccctt ttggctgtta
    33241 ctctagcagg agcaggctat gtttatagtg ctttaaatcc tgttgataaa aatagtgatg
    33301 cctttgttca agttgagata ccatctgggt caggcaataa attgattggt caaattcttc
    33361 aaaaaaaagg tttaatcaag aatagcactg tttttagttt ttatacaaaa tttaaaaact
    33421 ttacaaattt tcagagcggg tattacaatc tgcaaaaaag tatgagtcta gaagaaattg
    33481 ctagtgcttt acaagaaggt ggtacagcag aacctaccaa gccatctctt gggaagatct
    33541 tgattccaga aggatacacg attaaacaaa tagctaaagc tgttgagcat aatagcaagg
    33601 gaaagaccaa aaaagctaaa acacctttta acgagaagga ttttttggat ttagtcacgg
    33661 atgaggcttt tattcaagat atggtaaaaa gatatccaaa attattagca actatcccaa
    33721 ctaaagaaaa agctatttac cgtttggaag gttacctttt cccagcaacc tataactatt
    33781 acaaagaaac taccatgaga gaacttgtag aggacatgct ggcagctatg gatgctactt
    33841 tggtacccta ttatgataaa attgctgcta gtggtaagac agtcaacgag gtattgacct
    33901 tggcctcttt ggttgaaaaa gaaggttcaa cagacgatga cagacgtcaa attgcaagtg
    33961 tcttttataa ccgccttaat agcggaatgg cactacaatc taatatagct attttgtatg
    34021 cgatggggaa acttggtgag aaaacaacct tggctgagga tgctactatt gacaccacca
    34081 ttaattctcc ttataatatt tataccaata caggtctgat gcctggtcca gttgctagct
    34141 cgggggtttc tgcaattgaa gcaaccctaa atccagcctc aacggattat ttatactttg
    34201 tggccaatgt ccatactggt gaagtttact atgcaaaaac atttgaagaa cactctgcaa
    34261 atgttgaaaa atatgtgaat agtcaaattc agtaaacaca aacatggtgc ttaagcacca
    34321 tgtttgtgtt tctgattcgt tcaaaaaaga aaagagagaa aacaattatg gcagaaaaaa
    34381 cgtatccgat gaccctaacg gaaaaagaac aacttgaaaa agaacttgaa gaattaaaac
    34441 ttgtgcgtcg tccagaaata gtggagcgta ttaaaattgc acgttcgtat ggagatcttt
    34501 cagagaactc tgaatacgat gccgcaaaag atgagcaagc ttttgttgaa ggtcaaattt
    34561 caacgcttga aactaagatt cgctatgctg aaatcattga cagtgatgct gttgcaaaag
    34621 atgaagtcgc tatcggaaaa acagttatcg ttcaagaagt tggaacaaca gataaagata
    34681 cctatcatat tgtaggtgct gctggagcag atatcttctc aggaaaaatt tcaaatgaaa
    34741 gcccgattgc tcaagctttg attggtaaaa aaacaggtga caaggttaga attgaatcac
    34801 cagcagctac ttatgatgtt gaaatcatca gcgttgaaaa gacaaattaa tcagatgaag
    34861 ccattatttg cctaaccact aagtgttttg gttgctaatg gcttttctag tatcttcaaa
    34921 tgaggttgac tgttaggaag gtcaagtatt aatcgtattg attatgagcc aagaggacta
    34981 tagatcaaag atcgttttcg atggttattt aatgccaaaa gaaaagacca gcaccttaat
    35041 gtactgaccc caaaaagttg gacactatat tttaaggaag tgtataatct aaggaaactg
    35101 acactaatga ttgaccgttt tgcaagactt tattaatgat ttcttgcttt attttaaatg
    35161 aataagtctg atacgtttcc ttccttaaca ctatcgactc cataatgacc catcagtcaa
    35221 acggtatatc tcaaacgact acggtttact ccaaattgat tggctagttg aggccaagaa
    35281 acacctgatt tttttaatgc taaatttcta gcttatcttc atagcttaat ttcatacaaa
    35341 aacaccccaa tcgttagatt tttttgatat gtcccctttc actagatgag tccagtaaaa
    35401 gggggcatat cgttttttgt ctaacttttg gagtgcagtt cataattgtg ctaggttttt
    35461 tgtctttctt aacgctttcg ctgttttcca gcattacgat tggattttat ttttttaggc
    35521 aagttagcct gttccatgtt ttgtgaaggc gtaacatcct tacgagaaga agttgattgg
    35581 tatgctttag gcgggttttt agcgtattct tctttaattt gcttatgcaa tcgaggtttt
    35641 aagaggtagg ttgtgattaa ctgttgaata atactaaaga aaccaccaac tagccagtaa
    35701 agaccaacac cagcagggag tgagaaggac atgaagatca tcatgatagg catggtgtac
    35761 atcatcgtct tcatttgctc acgttgttct tctgaaacgg ccatcattga taaccatgat
    35821 tggaagaagt aaagagcagc gataattgct gttaacacta aactacggct accaagatca
    35881 atgcccataa aggtgcttgt tgatactcct ttagtgtatt gagcggcaaa atacatggca
    35941 gaaaagaatg gcatctggat gagaagaggt agacatccaa tacctccaag agggttaatt
    36001 ccatgagcac gctgagcagc cattaattct gtttgggcag ccattttttc ttcctggcta
    36061 cttgcctgtt tgatacgttt gttgattggt tcaaaaacag gtttcaagaa ggccattttc
    36121 tcagattgat aacttgcttt ccaagattga tagagaccta gtggtaagat aagtgttcta
    36181 acaataatgg ttacgatgat gatagccagt ccataaccta gtccagcatt gtttgcaaag
    36241 taatcgataa agtatgacat gggttttcca agaaattccc aaatcatacc tttgggattt
    36301 ccgtgagcgt ctcttcccac acagcctgtc aaggtgaata gaattgacag tgctagtcct
    36361 gaaaagagga tgcgatttaa tgttagtttc aatgtgttta tcctttaatt ttaatatact
    36421 tatctatttt acagtttttt tcagaaattc acaatagttc tgaaggccga tttttaattg
    36481 cctatttgaa agtcctgaaa gtcttcaaaa ttagccatgg tgacatccac ataagtgact
    36541 tttgcccatt tggatggtcc tttacgaact tcttgaataa atgtggctat tttatctgaa
    36601 tcttttgatt gggccagaat ttcaacggtc ccatcgttgt tattccagac acgaccataa
    36661 atatctccta tatctagagc taaagtatga gtagcgtgtc gaaaaccaac accttgtaca
    36721 cgtccagaaa caattaaacg tactttttgc ataagaaggg cctccttgct tttattatag
    36781 cacatactta gcaggaaatc tctttagcca attgtctact tcctgtcact tttactaaag
    36841 acaagaatac aaaaatgaga tagttagtag tactaacagt aaaagagatt tgtctatttt
    36901 aaaaatagta tcaaaaaaag gtcttttagg tttaaaacat tgaactgccc ccaaattgac
    36961 catctaagaa gttgatgctt tcaaatgctg tcgcgtatgg tataataggc gcatggttat
    37021 tacatcaaaa gcaaatcaac taattaagca aacaaaaaaa ttattgcaaa aaaagcatcg
    37081 aaaacagtcc tatttgattg agggctggca cctttttgaa gaagcccaaa aatcaggaca
    37141 agtttttcgc cacatctttg ttttagagga aatggcggag cgtctagcag gtgagcaaga
    37201 actcgttatt gttagcccac aagtgctcaa ggagttgacc gactctccta gtccacaagg
    37261 cattgttgct gaggtggaga tacctaagtt agcctttcca tcagattaca aagggaaata
    37321 tttggtttta gaggacgtcc aagacccagg aaatcttggg accatcattc gtacagcaga
    37381 cgctgcacgg tttgatgggg tctttctttc tgaaaaatca gcagatattt acaaccaaaa
    37441 aaccctacgt tccatgcaag gtagccattt tcatttacca atttggcgaa cagatgtcta
    37501 tcagctttgt cgagagctac aagagtataa aactcccatc ctagcaacaa ctctgtcaaa
    37561 gaaatctgtt gattataaaa gcctcacaca tcatgaaagg ttggctttgg tgttgggaaa
    37621 tgaaggccag ggcattagtg ctgaaatggc agccctagca gaccaactgg ttcatattac
    37681 aatgcctggt caggcggaaa gtttgaatgt tgccgtagca gcaggaatcc tcattttcag
    37741 cttgatttaa gctaatatga tataataacc aagtgaggta attatgttat gcattataca
    37801 gaagataaag aatatatgga acacgtcggt catttgatcg ctcatcctcg ctttcaaaaa
    37861 ttgagtcata ttgttcagca ccaacattca acgcgtcttg aacattctat caatgtttct
    37921 tattcaagtt ataaattagc caagcgattt ggttgggatg ctaaaagtac agccagaggg
    37981 ggcttacttc atgatttctt ttattatgat tggcgcgtga ccaagtttaa taagggtcat
    38041 gcctgggttc atcctcgtat tgctgtacga aatgcgaaaa agttaacaga actcaataaa
    38101 aaagaagagg atatcattct aaaacacatg tggggagcga ccattgcttt tccgcgttac
    38161 aaggaaagtt atattgtgac aatggtagat aaatactggg ctgtcaagga agcagtgacg
    38221 cctttaagac aaaaatggtc taatcgacgg tttcttcgcc gcaagaccct ccaaagtcat
    38281 aatcgttaag taaaggagtt attatgaacg atcacattat ttatacacaa tcagatgtgg
    38341 gattaaatca gttttttgct aaaatttata gtctagtggg aatgggagtg ggtttgtctg
    38401 cttttgtttc ttatttgatg ctttatccat ttagagaaaa tttaatctct attcttgtta
    38461 atcagccgat gatttactat ggtgctgcga ttattgaact tattttagtt tttgtagcca
    38521 gtggtgcagc acgaaaaaac acaccagctg cattgcccat ttttcttatc tattctgcgc
    38581 taaatggctt taccctaagc tttattattg tggcatacgc tcaaacgaca gtttttcaag
    38641 catttctttc ttcagcagct gtgttttttg ccatgtcaat cattggtgtc aagactaagc
    38701 gggatatgtc aggtcttaga aaggctatgt ttgctgcttt gattggtgtt gttgtggcta
    38761 gtctgattaa tctttttatt ggtagtggga tgatgagtta tgtcattagt gtgatttccg
    38821 tgctaatttt ctcaggtctc atcgcatcag ataatcaaat gattaagcgc gtttatcaag
    38881 caacaaatgg ccaggttggt gatggctggg ctgttgctat ggccttaagc ttgtatttag
    38941 attttattaa cttatttatc agccttcttc gtatttttgg aagaaatgat taacattaaa
    39001 aagtgagtat aactactcac tttttaatgt taacaggata agtaaactgt aaggaagaaa
    39061 ttcgagatag atataagatg aggctgctaa aagacctagt gttaatttgt aaactctttc
    39121 tttttttggt atactattaa ggattaaata cgaggagaat atagatagat atgtcaacag
    39181 ctatttggat tttattactt attgttgccc ttggggtagg tgtttttggt gggattttta
    39241 ttgcccgtaa acaaattgaa aaagaaattg gtgaacaccc acgtttaaca ccagaagcta
    39301 tccgtgaaat gatgagccag atggggcaaa aaccaagtga agcaaaaatc caacaaactt
    39361 atcgtaatat catcaaacaa tcaaaagcag ccgtatccaa aggtaaaaaa taaaagctaa
    39421 ttgttatagg ggaaaccttt gtgatagtta gaagtgaaca gtctttgatc tcaatgttca
    39481 gtagcacttg tcttatcagt tagatttgtc aactgttcag ggtttaaaaa gaaactcagt
    39541 tggctatttc caactgagtt tttcatatcg tcagtaagga agtaaacata atggatacaa
    39601 gaccaattgg gtttttagat tctggtgtgg gaggtctgac cgtcgtttgt gaattgattc
    39661 gtcagctccc tcatgagaag attgtatata ttggtgattc agctagggcc ccttatggtc
    39721 caagacctgc tgagcaaatt agagaataca catgggatct tgtccgtttt ttgctgacca
    39781 aaaatgtgaa aatgattgtt tttgcttgta atacagcaac agcagtagct tgggaagagg
    39841 tcaaagaagc tctggacatc cctgttttag gtgtgatttt acctggatca agtgcagcaa
    39901 taaaatcgac aaccaaaggt caggttggtg tgattggaac accgatgaca atagcttcgg
    39961 acatttaccg tcaaaaaatt caattactag caccaacagt agaggtggct agcctagctt
    40021 gtcctaaatt tgtccccatt gtcgagtcta atgaaatacg ttctagcgtc gctaaaaaag
    40081 tcgtctatga aagtttgacg cccttggtgg gtaaaattga cacgctcgtt ctaggctgta
    40141 cgcattaccc tctgcttcgt ccgattattc aaaacgttat ggggccgtct gttaagctga
    40201 ttgacagtgg agcagaatgc gtccgagata tctctgtctt attaaactat tttgacatta
    40261 acggtaatta tcatcaaaaa gctgtcaaac accgcttttt tacaacagca aatcctgaga
    40321 tttttcaaga aattgcctcg atttggctga aacaaaaaat aaatgtggag catgtcacct
    40381 tatgagtgaa aaaatttacg aatacaaaga tgaaaataac tggtttatcg gaaagatgac
    40441 tggtcataat ttaatatcgg gctggggagt caaacacacg acaatcaaaa aaatagatga
    40501 ccttttagac ggtattgccg caacgttaga ttgggaaaat cctaaaggtt acgatgtttc
    40561 ggtggtgcgt tatcagtctc ctttatttct catcaccttt attatcgata tgattaacca
    40621 agaaacccag cgtgagatta aggtgattcc ccatgcaagc acgattttat taatggaaaa
    40681 tgcgaaactg cttgcagttt atctcccaga aggtggagtt tcaacggcta cattttttgc
    40741 gactagtgaa cagggatttg gggatactat tttaatcgct acacgaaacg agggaaaaac
    40801 caaagagttc cgcaatctgt ttggccagct aggttatcgt gtggaaaatc tcaatgatta
    40861 tccagaattg ccagaagtgg cagaaactgg tactactttt gaagaaaatg ctcgcttgaa
    40921 agcagaaacg atttcacgcc tcacaggaaa aatggtatta gcagacgatt caggactaaa
    40981 agttgatgcc ttgggtggtt tacctggagt ttggtcagct cgtttctcag gaccagatgc
    41041 cacagatgcc aagaataatg ccaaactctt acacgaatta gctatggtgt ttgaccaaaa
    41101 gaagcgctca gctcaatttc atacgacttt ggtagtggct gctcccaata aagatagttt
    41161 ggttgtgaaa gccgagtggc caggctatat tgctacgcag cctaagggag aaaatggttt
    41221 tgggtatgac cctgtcttta tcgtcggaga gactgggcgt catgctgcag aattagaggc
    41281 tgaccaaaag aatcagttgt cgcatagagg tcaagcagtt cgaaaattaa tggaggtctt
    41341 tccagcatgg caagcaaaac aatcatagta atgagtgact ctcatggtga ccgagatatc
    41401 gttcaagcca ttaaagataa gtatcttggt caagttgatg ctattttcca taatggggat
    41461 tctgaattaa acagctcaga tcctatttgg gctggtattt atgtcgttgg cggtaattgt
    41521 gactatgata caggttaccc tgatcgttta gtaactcaat taggcacagt tacgattgcc
    41581 cagacacatg gtcacttgta ccatattaat ttcacttggg ataaactgga ctactttgct
    41641 caagaagtag cagcagatat ttgtctatat ggacacctac accgtccagc tgcttggcaa
    41701 gttgggcaaa ccctctttat gaatcccgga tcagtaacac aacctcgcgg agaaattaac
    41761 gagaaattat atgctcgtgt tgaactaact gatactcaaa ttaaagttga ttactttaca
    41821 agagatcata aactttaccc atcactgtct aaggaattta aacgatgatc gcaaaagaat
    41881 ttgaaacgtt tttaatgagt catttagata attatcttat cccggaacaa gacttggcta
    41941 tttttatcga cacacataat gcagaccatg tgatgttact attggtgagc aatggttttt
    42001 ctagagttcc tgttatcaca cgggagaaaa aatatgtggg aaccattagc atctcagata
    42061 ttatgatgta ccaatctaaa aggcagctga cagattggga aatgagtcaa acagatattg
    42121 gcgagatggt taataccaaa attgaaacca ttagcattac ttctagccta acagaaatta
    42181 tgcacaagtt aattgatttc ccattcttac cggttgtaga tagagcgaat cgctttgttg
    42241 ggattattac gcgaaaatct atattaaagg ctgtcaacag tcttttacat gattttacag
    42301 atgattacac gattataaaa aaatgaagag ttatattgaa ccttttattg ctagcaaggc
    42361 tttatctcaa aatagtcaaa aagcttatcg atacgatttg caacagtttt gtcaactgat
    42421 tggtgaacgt gtcaatcaag acaaactatt actttatcaa aatagcatag ctaacctaag
    42481 tttatctgca aaaaaacgca aattatcaac agctaatcaa ttcttatatt acttgtatca
    42541 aataaagtat ttaaatagct attttcgatt aacagacacc atgaaagtga tgcggactga
    42601 gaagcagcaa gctgctatta ttaatactga tattttctat caaaaaaccc cttttgtgtg
    42661 ggggcaatta atcagcttat taatattgga gctgggttta actccgagtg aagtagctgg
    42721 tattgaagta gctaacttgg atttaaattt tcaaatgttg acgctaaaga ctaaaaaagg
    42781 tgtgcgtgta ttacctttat cgcaaatact aatccctttt ttagaacaac aactcgttgg
    42841 caaagaagtc tatctttttg aacatcgagg catccctttt tcaagacaat ggttttttaa
    42901 tcacctaaaa acctttgttc gaagtattgg ttatgaagga ttaactgctc aaaaattacg
    42961 agagcaattt attttgaaag aaaaactagc tggtaaatcg ataatagaac ttagcgatat
    43021 tcttgggctg aaaagcccta tgaccttaga aaaatactac aaatcataat ggatataaaa
    43081 cttaaagatt ttgaaggtcc tcttgattta ctcttacact tggtatcaca gtacaaagtt
    43141 gacatctacg aggttcctat tgttgaggtt attgagcagt accttaatta tattgaaacc
    43201 ttacaggtaa tgaaacttga agtggctggt gactacatgc tgatggcaag tcagctcatg
    43261 ttaatcaaaa gtagaaggct attaccaaag gtggtagaac acatcgaaga agaagattta
    43321 gaacaagatc tgttagaaaa gatcgaagaa tatagtcgct ttaaagcagt tagtcaagcg
    43381 ttagcgaagc aacatgacca aagggcaaaa tggtattcaa aacctaaaca agaattaatt
    43441 tttgaagatg ctatcttaca ggaagataaa acggtgatgg atctatttct agctttttca
    43501 aacataatgg cagctaaaag agcagtttta aaaaacaacc atacagtcat cgagcgtgat
    43561 gattataaga ttgaagacat gatggcttct attaaacagc gactggaaaa agaaaacgtt
    43621 attagcttat cagcgatttt tgaggaatgc caaacattaa atgaagttat cagtatattt
    43681 ttagctagtc tagaattgat taagcttcac gtggtatttg tagagcagtt ctctaatttt
    43741 ggggctatca tactacgaaa ggagaagaaa tgacgtattt gtcacagata gaagcgctgc
    43801 tatttgttgc aggtgaagaa ggattaagtt tgcgacatct agcgtctatg ttatcattaa
    43861 cgccaacagc tcttcaacag caattagaaa aactctctca aaagtatgaa aaagatcaac
    43921 attctagtct ttgcttgata gaaacagcta atacctacag gctagtaact aaagaaggtt
    43981 ttgcagaact cttgcgtgct tatgccaaaa caccaatgaa ccaaagttta tctcgtgcga
    44041 gtttagaggt cttgtctatt gttgcataca aacaacctat tacacgaata gaaattgatg
    44101 acattcgagg ggtaaactcc agtggagctt tgagtaaatt attggcattt gatctcatta
    44161 gagaagctgg caaaaaagat gtggttgggc gtcctcattt gtatgcgaca acagattatt
    44221 ttctggacta tatgggaatt aatcatttag acgaattgat tgaagtatct gccgttgaac
    44281 cagcagatga agagattgct ctttttagga cacaagactg agttttgctt gtcatcaaat
    44341 agcaaatggc gtttacaaaa ggatttgttt taaggcgttt tagttgaaaa aagccttaaa
    44401 ctagggacaa caaaaagttg ctcaaaagaa agaagaatat aatgcgaatt aacaaataca
    44461 ttgcccatgc gggtattgcc agtcgacgta aggctgaaga attgattaag caaggcttag
    44521 taaccttaaa tggtcaggtt attacggatt tagcaaccgc tgtaaaatcg ggagacgtgg
    44581 ttgaaataga aggaagtcct atttacaacg aggaaaaggt ttactatttg cttaataaac
    44641 ctcgtggcgc tatctcaagt gtgtcagatg acaaaggccg taaaacggta ctggatttac
    44701 tacctcaggt taaagaacgc atataccctg ttggacgatt ggattgggac acatcagggg
    44761 tccttatttt aacgaatgat ggtgatttta cagatactat gattcatcct agaaatgaaa
    44821 tagacaaggt ttatctagcg cgtgtcaaag gtattgcaac gaaagaaaat cttcgtccct
    44881 taactcgagg aattgttatt gatggtaaaa agaccaaacc agctcgctac aatattgttc
    44941 gtgtagaagc tgataagaat cgatcgattg tagaattgac tatccatgaa gggcgaaacc
    45001 atcaagtgaa aaaaatgttt gagtctgtgg ggcttttggt tgataaatta tctcgtacac
    45061 gttttgggac cgtcgactta aagggactaa gaccaggaga agcaagacgc ttaaataaaa
    45121 aagaaataag tcaactgcat aacttagcta atacgaaaaa atgatgaaaa aactattaat
    45181 agtatctgtt aaagcttatc aaaaatacat ttctccttta tctcctccta gttgtcgcta
    45241 caagccaacc tgttcagctt atatgttaac tgctattgaa aaacatggta ctaagggaat
    45301 actaatgggg atagcaagaa tattaagatg tcaccctttt gttgctggtg gtgtcgatcc
    45361 tgttccagaa gattttagcc taatgagaaa taaaaacacg tctaaaaacg ctgaaaaggc
    45421 atgactttat caaaaaatgg cttgacattg atagctgaag tgttataatg gaaaacaagc
    45481 attcgttggt ttaaatcaaa cctgttatga tttaagttag cgagtcacca tcaaccacat
    45541 tgtttgctga gcatgactcc gagcagtgtg gttttttaaa ttaaaaagag taaatgagat
    45601 tatgacgaca aaagaactta tcaacaaaaa cgacaaagta aaaaaggctc gcaatcatat
    45661 tgtcctgttt caaccccaaa ttccacaaaa tactggtaat attgctagaa catgtgctgc
    45721 aactaatgca cctttacata ttattaaacc catgggattt cctattgatg accgcaaaat
    45781 gaagcgtgcc ggcttagatt actgggacaa gttagaactg catttttatg atcatttaga
    45841 acagtttatc aatcaatgtc acggacagct tcacttgatt agcaagtttg cagttaataa
    45901 ttattctcaa gctacttatg ctgatggcga ttcccattat ttcttgtttg gacgagaaga
    45961 tacaggcctg ccagaagatt ttatgcgaga acatgctgaa aaagcacttc gtattccgat
    46021 gaatgatgag catgtacgga gtttaaatgt ctcaaatacg gtttgtatgg tgatttatga
    46081 agcccttaga caacagggct ttcaaggatt agagttaaag catacttacg aacacgataa
    46141 actaaaataa tggacttttt aaaagcgtca gtttttggca acatgcgttg tcagtagctg
    46201 acgcttttaa aaatttagtc aaagctattg ctatctaggt ttaaatctgc tatgctagaa
    46261 gtgtcttcag ggcagggtgt gattcccgac cggcggtgac tagtaactag aagtccgcga
    46321 gcgcaagctg atgtggtgta actccacaac cgacagtata gtctggatga gagaagaccg
    46381 ggctttttgt gtaggcttat tttagctaca caataacgac ggaacttctt tcaatttgaa
    46441 aaaattggag gaatttttta atgtcaaaaa cacataaaat gattatgatt ggtatacttt
    46501 ctgcgatatc atttctattg atgctagtta gctttgccat tattccaggc gcagcttttt
    46561 taaaaattga atttagtatt attcctgtcc tatttggttt aatgattatg gacttaaaga
    46621 gtgcttactt gattttgtta ttgaggtcct tattgaaact ctttttgaac aatcgtgggg
    46681 ttaatgattt tattggtctc ccaatgaata ttatcgctat cgctttattt gtgacggctt
    46741 tttccttagt ttggaaccgt caaaaaacgc ttagtcaata tgtatttgct agcttactag
    46801 gcacagggtt attaacattt ggcatggttg ttctcaatta tacttttgcc attcctttat
    46861 atgctatatt tgcaaatatt gatatcagag cttatattgg tgtcactaag tatatgatga
    46921 ctatggttat tccgtttaat cttgttgaag ggttgatatt tgcaattacc ttttattttg
    46981 tgtatattgc aagtaaacca attttagaaa gatacttaca ctaatatgat gacaaataaa
    47041 caaactaact ttttaatagc ttcttttgca ttactaacct ttgttataat aggctatacg
    47101 gtcaaatttt ttcctgaacg tttggcactt ctagataata ctattcaagc agagattaga
    47161 ggcaaccttc ctatagtgct gacgcaattc tttaggggtg ttactgtatt tggaaatgtc
    47221 atgacacaaa ttttgttagt tattgtgtcg gtcctagttt tattctttat gaagtggaaa
    47281 attgaagcct tgtttatctt atcaaatggt gccattgcag catttttgat tacgactctc
    47341 aagctctttt accaaagacc aagacctgct attgagcatt tggtttatgc tggtggctat
    47401 tcgtttccca gtggccatgc gatgggtagc atgctgattt ttggtagcct attgattatt
    47461 tgttatcaaa ggctacattc aaaactatta caatttgtga ctagcatgat ttttataata
    47521 ctaattttag taattgggtt atctcgtatt tatctagggg tacactaccc aagtgatatt
    47581 ttagcaggct ttgtattagg atttgggatt ttgcagttta tttatccttt ttataagcaa
    47641 aaacgatttg aatggcgatt tcttttgaaa caagactaat ttttcttgag aagacatagg
    47701 gcttatttaa atcatttaga ataacattgg caagcatcac cccttgattg ccagtgttat
    47761 tttagtttta gttagatgat gtgagctgat gattagtaaa tacgtttaga taaaaaacga
    47821 ttaaagtgct atgtaacgtc agaaaagacg tgatttttgt tgatctgtag tcattaagta
    47881 agctgatgta gaagtagtga attctaatga ctgagctatc ttttgcatag atgactatct
    47941 tgctagtaat gatttgtgct acaatagaaa catgaaaaaa agatatcaga cattaaacga
    48001 gcattaccgt caactatttg gcgcaaaaat gtttaaagtt ccgattgatg ccggctttga
    48061 ttgtcccaat cgtgatggaa cggtagctca tggaggatgt actttttgca cagtatcagg
    48121 ttctggagat gctattgtag caccagatgc tccaattaaa gagcaatttt ataaagaaat
    48181 tgattttatg caccgtaaat ggcctgatgt caatcgctat ttggtttatt ttcaaaactt
    48241 taccaatact catgatacag ttgatgtgat tcgcgaccgt tacgaacaag ctattaacga
    48301 acctggagtt gttggcatta atattggcac acggcctgac tgtctaccag atgataccat
    48361 tgcttactta gcagaattat cagaacgcat gcatgtgaca gtggagctag gcttacagac
    48421 aacttatgaa gaaacttcta ggctaattaa cagagcacat tcttatgatt tgtataaaga
    48481 aacggtgagg cgactaaggc attaccccaa cattaatatt gtctcgcact tgattaatgg
    48541 attgccaaaa gaaactcatg acatgatgct tgaaaatgtg agacgctgtg taacagacaa
    48601 tgacattcaa ggaattaaat tgcatttgct gcatttgatg accaatacta gaatgcaaag
    48661 agattatcat gaaggacgct taaagttgtt gagtcaaaag gactatgttt cgattatttg
    48721 tgaccagcta gagattatcc ctaagcatat tgtgattcac cgtattacag gagatgcccc
    48781 acgagatatg ttgattgggc ccatgtggag tctaaataag tgggaagtat tgaatgccat
    48841 tgataaagaa atggaaagac gaggaagctt tcaaggctgt aaagttgact aatttgtctc
    48901 attttgacgg atttggatag gagaaaagtg atgctaaaac gccccattca tctctcgcat
    48961 gattttttag cggaggttgt ggataagtct agtgtggttg ttgatgccac gatgggtaat
    49021 ggaaatgata ctgccttttt ggcacaatta gctaaaaagg tttatgcttt tgatgtgcaa
    49081 gaacaagcta ttagaaaaac aagtgagcgg ttagcgcagc taggattatc gaacgctgag
    49141 ctgattttag cgggtcatga agcagttgat cagtatgtga cagagccggt gcgtgcagcg
    49201 atttttaacc ttggttattt gcccagcgca gataaatcta ttattacctt accaaatacc
    49261 acactccaag ctttatcaaa actactaacg ttattaatgg taggtggacg tattgctatt
    49321 atggtctatt atgggcatga tggaggcagt ttggaaaaag atgctttatt agattttgtc
    49381 aagcaattag accaaagaaa ggtttctgca atgctttatc agcctcttaa tcaggtgaat
    49441 accccacctt ttttaatcat gttggagaaa ttagcagacg tttagccctt atccctgtgt
    49501 caagtctact agaagttctg cgattatttc ggtggaaaaa gaagaaatcc cataggcttt
    49561 ggctataaat gtgatataat gaagtcacta tattattttt ttaggagtta cattaacatg
    49621 gaagaccctg tgagtcagcc cttagtgatt caatttttat tgttagttgt tttaaccttg
    49681 ttaaatgctt ttttttcagc cagtgaaatg gccttagttt ctctcaatcg ttctcgggtg
    49741 gaacaaaaag cagcagacgg tgataaaaaa tacgctcgtt tgttgcgggt tttagaggaa
    49801 cctaatcatt ttttatcaac gattcaagtt gggattacct ttattagttt actatcagga
    49861 gcaagtttat cagcttcttt gggtaaggtg atctcaggtt ggctaggtaa ttcagcgacc
    49921 gcaaggacag ctggtactat catctccttg gttttcttga cttatgtctc tattgtttta
    49981 ggagaattgt atccaaaacg gattgccatg aacctcaaag acaagttggc gattgtttca
    50041 gcccctatta tcattgggtt agggagactg gttagtccct ttgtatggct cttatcagct
    50101 tctactaatt tactgagccg acttacccct atgacctttg atgatgcaga tgagcaaatg
    50161 acacgtgatg aaatcgagta tatgttatca aaaagtgagg cgacccttga tgctgaagaa
    50221 attgagatgt tgcaaggagt tttctcactt gatgaaatga tggcgcgtga agtcatggtc
    50281 ccaaggaccg atgctttcat gattgacatt aacgatgatc cgcttgaaaa tattcaggaa
    50341 atcttaaaac aaagtttttc acgcattcct gtttatgatg tggataaaga taaaattatc
    50401 ggtctcatcc acactaagcg tctcttggag tcaggtttcc gccagggatt tgatcagatt
    50461 aacatgcgaa aaatgttaca agaacctctt tttgttcccg aaaccatttt tgtagatgat
    50521 ctcttacgcc agctgcgcaa tacccaaaat cagatggcta ttttgctaga tgaatatggt
    50581 ggtgtggcag gacttgtgac tttggaagac ttgcttgaag aaatcgtcgg tgaaatcgat
    50641 gatgaaaccg ataaagcaga acaatttgtt cgtgagattg gagacaatac ctatattgtt
    50701 gttggtacta tgactttaaa tgagtttaat gactattttg ataccgaact agaatcagat
    50761 gatgtagata ccattgctgg tttttatttg acaggtatcg gaaccattcc aagccaggag
    50821 caaaaagaag cctacgaaat agataacaaa gacaaacatt tagttctaat caacgataaa
    50881 gtcaaagatg gccgtattac gaaattaaaa ttaatcctgt ctaatataga acagattatt
    50941 gaggaagact aggctccatg cctagtcttt ttgatgaaaa gtgttataat gaaaatgtaa
    51001 aaacgtttac aagtaataaa ggagatgcaa tgactgagaa agattatgga caagtaacag
    51061 ggatggtgca ttcgacagaa agttttggtt ctgtagatgg tccaggcatt cgttttatca
    51121 ttttcttgca aggctgtaaa ttacgttgcc aatattgcca taatccggat acttgggaga
    51181 tggaaaccaa caattcaaaa atcagaacag tcaatgatgt cttgaaagaa gcccttcagt
    51241 acaaacattt ctggggaaaa aaaggaggaa ttaccgtatc tggtggtgaa gctatgcttc
    51301 aaattgattt tatcactgcc ttattcatcg aagctaaaaa attaggtatc cataccacac
    51361 tagacacctg tggctttacc tatagaccga cacctgaata ccatcaggtt cttgataact
    51421 tattggcagt gaccgatttg attttattgg acttaaaaga aattgatgaa aaacaacata
    51481 aaattgtcac gcgtcagcct aataaaaaca tattgcaatt tgctaggtat ttatccgaca
    51541 agcagattcc tgtctggatt cgacatgtct tggttccaga cttgactgat attgatgatc
    51601 atttgacacg attgggtgag tttgtcaaaa ccttgaaaaa tgtctataaa tttgaagttt
    51661 tgccttacca taccatggga gaattcaagt ggcgtgagct aggtattcct tatcagttag
    51721 aaggtgttaa accaccaact aaggaacgcg ttcaaaatgc caaaaacttg atgcaaaccg
    51781 agtcttatac agaatacatg aatcggattc atcagtcata agagctgtta tagggttgag
    51841 gtttcctcaa ctttttaaag tattataagc agatcttttg taatcttcct ttgattttag
    51901 ggggtaattt tgctaaaata aaatgaataa acaaaatgag gtagaatgat tatgtcaaaa
    51961 attttagttt ttggtcatca aaatcctgat acggatgcta ttgcatcatc ttatgctttt
    52021 gattacttat cccaaaaagc gtttggtttg gatactgaag tcgtagcttt aggaacacct
    52081 aacgaagaaa cagcttttgc ccttgattat tttggtgttg aggcaccacg tgtggtagag
    52141 tctgctaaag cacaagggtc tgaacaagtg attttgacag accacaatga attccaacaa
    52201 tccattgcag atatccgtga ggttgaggta tatggtgtga ttgatcacca ccgtgtggct
    52261 aattttgaaa ctgcaaatcc tttatacatg cgtgtggaac cagtaggatc agcctcatct
    52321 attgtttacc gtatgtttaa agaaaatggc atcgaggtgc caaaatcgat tgcagggatg
    52381 ctcttgtctg gtttgatttc agataccttg ttgttgaaat ctccaacaac tcatgtgtct
    52441 gatcaccttg tcgctgaaga attggcagag ctagcagaag tgaacttgga agactatgga
    52501 atggctcttt taaaagcagg tacaaacctt gcaagcaaat cagaagtaga attgattggt
    52561 attgatgcca aaacatttga attaaatggc aatgctgtgc gcgtggcaca agtgaacact
    52621 gttgacattt cagaagtctt agaacgtcaa gaagctattg aagcagccat taaagatgcc
    52681 atggctgcag aaggttattc agactttgtt ttgatgatca cggatattgt taactcaaac
    52741 tctgaaattc tagctattgg agcaaacatg gacaaggttg aagcagcctt taacttcacc
    52801 cttgacaaca atcatgcctt cttagcaggt gccgtttctc gtaaaaaaca agtggttcca
    52861 caattgacag aaagttttgg agcttaatga aaggacgctt taaaaggact tggttttttt
    52921 gaccaagtcc ttttttcact cttctatgct ataatagaag gtatgataac aatatttcat
    52981 tcagataaac tcaccagaca acctttcttt caagacctta tcaattatct cgaccagcat
    53041 gatcacgtta tattacgaga gatcaaaaaa gcctttccta atgtgacagg tattgacaag
    53101 gccatcgaaa gctatgttca agctggctat attcgccgtg aaaataagcg ttatggcatc
    53161 aaccttcctt tggtgagttc tgatcagcag ctggccttag acactatgtt ttttgtggac
    53221 acctgttcag ctatgtatga aaatatttta gcggttgttt ttgagactca gctaacaaac
    53281 caaaccaatc acgtgatgat caaggaaaag accaacatca cgagaagtca gttgactcta
    53341 gctaattatt tttaccgtct caaaagaggt gagaagccat cagctgagca gatggacttg
    53401 tatgacctct tgggggatgt gaatcaggaa tatgccctta aatatatgac aacttttttg
    53461 cttaaattca cgcgcaaaga ccttgtgatg caaaaacgtc ctgatatatt tgtggaagct
    53521 ctggttacac ttggttacct aaaacaagtg gagcctacaa cataccagct gctaatgacc
    53581 ttggataaag agagtttaac ctttatagca ccatagaaaa gagctaggaa caaggactgt
    53641 tcttagcttt ttgagtgctt ttattttgtt tttgccatta agtaaagaaa ataaggggct
    53701 ccgataagcg acactaaaat ccctgtctgg atattactgc caaccagata gactcgtcct
    53761 actgtatctg caacaagaag taggatcatt ccgattaaaa tactaatggg tatcgttatt
    53821 ttatgattac tccctaccaa gtatgtacta aagtgtccag ctattaagcc gataaaacta
    53881 atattaccaa ccaaaagaac actcaaagca cctaagccag ctgctaagac aagtatcaaa
    53941 cgacgcttac ggtttaaagg gagtcctagc ccaatagcag tattatcagc taatcccata
    54001 atattaagga aatgggcttg actataagtc aatagccaaa aacacaataa taaaggagcg
    54061 atgacactca gagtaggcca gtcgtctcct attaattggc cgctaagcca attgatgacc
    54121 aaatcgactt tgtagcgatt aatatgacca acaagagcaa ccattagact tgaaagcatg
    54181 gtagtaacag ctacaccagt aagaattaac cgtgtaggat caatttgtcc ttgttttgtc
    54241 aaagatagcc aataaacgct aaaggttgtt acaacagcac caagcatggc aaataaaggc
    54301 aagtaatggc tgatatgagc ttgctcaaag aaagaaaagg agaccacaat agccaaagag
    54361 atacctgctc ctatagtaat acctaataca ccagagtcag ctaagggatt tcgtgttaaa
    54421 cgttgtaata atagccctga taaagcaaga gaaccgcctc ctagacaagc agctagaatt
    54481 cttggcagac gaatgttaat aacgatgaaa gatatggcat ggctagattt tcccaaaaac
    54541 acatggataa ggtccaaaaa agatagatga gattctccaa gggacaaagc taatcccata
    54601 agacttacaa gtagcaggat caggctagta tataacctta aaaggtgtcg gtgagatttc
    54661 aatagcggcc tcctcttctt attaaccata aaaagcatgg aaaaccaatt aagctaacca
    54721 atgccccaag aggggtttca taaggcggat tgagattacg acaagcaata tcaacccata
    54781 ccatgaaact agcgccagaa actgcacaaa gcggcaaaag gtatcggtaa tgatgaggtg
    54841 taaaatgttt cataagatga ggaatgacta agccgataaa agaaatgctt ccagcaatgg
    54901 ctacagctgc tgatgataaa ataagaacca aaatcgtaaa gactgcactg atcaagttgg
    54961 ttttttgccc aagagctttt gcctgagact cacttagact aaggacggtc aggtgataag
    55021 ataatagctg ggctaaacaa agactaagaa taataagagg agcaatatag ccgatcattt
    55081 gccaattgac cccgacaaga cctcctgctt gccagccgat aacagcattt gccagatgat
    55141 agtaattggt aataccttga cctaatgctg atagcagtat ggaaaccata gctcctgcta
    55201 agacaaggcg gagctgatgg tagcctttgc cagattgata agaaaggcca aagactaagg
    55261 ttgctgccag gctagaccct aacaacgaaa gcagaataat gagggaatag tgcaagtgag
    55321 gtacaaacgc ataagccagt accaaggcta gtcctgctcc agcattaatg cctaaaaggc
    55381 caggctcagc gataggatta cgtgtgattg cttgcatgat agttccagaa acagctaacg
    55441 cagagccagt taaggtagca ccaaaaagtc tcggtaatcg tatagcgagt aaaacattgg
    55501 ctttatggcc gttttgcttt ccaaataaaa tagagttaag atcctgatgt gataaagcaa
    55561 cggctccaaa gcgcagatga cagtaaatag caacacataa gctaaaacta agtagcacaa
    55621 agacaagcca aaagatatgt gacttagtga ttatctgcgt tttttttaag caaaaacgct
    55681 cgagacacaa aaagggatgc ttagttttca cttgataaga ttgcctctcg taaagtctct
    55741 aattgatatt ctaaagaaag aggatcagta aagtaaaaaa cattggcatt gactttgatc
    55801 acatggtgtt ttttcacagc tggaatggat tgccatagct tgctttcata tagagcagaa
    55861 ccagtcttat catcttctgc agcaacgacg acataatcac caatatagtc tggcaagact
    55921 tcctgcgaca atgacaggta accttgttta aaaacttcag tcttcacttt ttcaggagca
    55981 tcataatgga aagcttgatg gataacctct ccgccacgtc cccagtcttt accaaaaagg
    56041 taaacgtctt tttcataaag ccccataata gtaaaggttg ctttgtcacc tgtaacggcc
    56101 ttgacttctt tttcataagc tgctgtttta gttttccaat cttttaacca cttcttggct
    56161 ttgtcttctt tgttaaagat gcggccgaag tcagataaca cttgtaaata atcacgtttg
    56221 cggtattcaa tcgagataac aggcgcaatt tctgccaatt gtttaatatt ttcttctgta
    56281 gagccaacaa caatgaggtc aggcttaagc gttgtaatgg cttctaaatc agttgcagca
    56341 acttgctttg ctttttttac agtctttgct aagatggggt ttttcttgtc ataagaagta
    56401 accccgacta gattcatatc taattttttg aggtaaccag tgtaagttga agccagactg
    56461 actactcgct taggctgttt aggaatatct ccgtaataag tcacaccagc aatttgaggc
    56521 ataggcgata aactttttga ggcggtgtta gaatgattag ttgcttgatt accacaggcg
    56581 attaaggtaa tagttgtcaa acagagtgtt aatagtagag ttaatttttt catgtatgct
    56641 aattctccta gaataaagtt attgaagctg ataagtcagc actataggac agttgtggat
    56701 aggatcatca accagtaccg gtttgatttg gaagatgtct tgaatgatag gtgaagtcat
    56761 aacatctgct atagtaccag tataatggat cttgccatgt ttcatagcaa tcagatgatc
    56821 cgaatagcgg gctgaaagat tgaggtcgtg aagaaccata acaatagtct tgccggcatc
    56881 cttatttagg gatttaacga gctctaggat ttctagttga tgatttaaat ctaaataagt
    56941 agttggctca tctaaaaaaa tagtatcagt gccttgggct aatgccattg caagccaaac
    57001 cctttgacgt tgccccccag aaagagcatc aacaggttga tcagcatagg ccatgacatt
    57061 ggtggcttgc atagcccaat gaatggcttt tttgtcagct ggactaagat ttccaaagta
    57121 agattgatgg ggaaaacgtc cgtaagaaac caattcgtaa acagttatgc cgttagttgc
    57181 ttcttgaact tgaggtaaaa gagctagttt tttagcaacc tctttagttt ctaatgtggc
    57241 aatgttttgc ccatttaaat atacaactcc ctgttttggt ggtaataatc ttgtcagtgc
    57301 ttttaataaa ctagacttcc cacagccatt ggcgccaata atggtcgtaa ttttaccttc
    57361 aggaatataa aacgataatt tatcgatgat ggtacgctgt tcataggcaa ttgtgaggtc
    57421 ttcagcacta attgttgtca tatggttgtc tcctttctaa aaagagtcaa agggttgatg
    57481 aaagtgcaca ttaaagtatt catctgtcca ttttaaaata gttgagaagt agcttatttt
    57541 ctcaaaatct tcactattat agcatagaaa aaaggcttaa caaagccttt tttgatgtga
    57601 tttttaggat gtattaaaaa agaaatatta gtttagaatg attaaaaaca atagcgataa
    57661 tcattctaaa ctaacgtcaa catactctag aggtagtgtc tggcgattgc taaatcacca
    57721 gcataagcta cttgttgtcc tttaacaatt tgataagcat ctgcgccttt cccagcgata
    57781 atcacagcat cttttgctcc ttggcaaaga gacatggctt tttgaatagc ttgctcacgg
    57841 tcactaataa tctctactgg gcgtgcgata tggctggcaa tttcttttga aatatcttct
    57901 ggatcctcga aattagggtc atcagcagtg agaatgacgg tgaggtttgg atgctgatga
    57961 atcaccctac caaaatcagc tcgtctgctc tcgcctttat ttcctggtgc acctaaaatc
    58021 aacattaatt tgcctgtctg atgttcttcc acaacgctga gtaatttttc taagctgtca
    58081 ccattatggg cataatcaac aaaaacttta gcatgatttg tcatagtgag gacttccata
    58141 cggcctggga cgcgagtctt agcgatacct ttttgaatat cagctaggtt agcacccaaa
    58201 cgaaggcagg caagtccagc tgccatagca ttttcttggt taaaatggcc aattaattga
    58261 atgtcataat ggccagctaa ttgtccttta gcttcaaagg agaaagcttg gctagtggtg
    58321 atttgattgt cagacaaggg accataaaac acatgctctt gatccgctac ctgatccgct
    58381 agaaatgaaa aatgatccat cccgctattg atcacaacag ctctgctatt ctccattaaa
    58441 agacgcttat gatagaaata atcttcaaac gttggatgct cgattgggcc aatatgatca
    58501 ggactaatat ttaggaaaac cccaacatcg aacgtaagcc catagacacg gtcaacgagg
    58561 taagcctgac tagaaacttc cataatcaag tgggtcatgc cattagtcac acactcagcc
    58621 atcatagcaa aaagatccaa gctctcagga gttgtgagtt gtgatttgaa aaaggtcttg
    58681 ccatctaagg tggtattcat ggtagaaaac atggcaggtt tataggattc tttcaacatg
    58741 tggtaggcaa aataagcagc cgtcgtcttt cccttagtac ctgtaaaagc tagtagtttg
    58801 agcttttctt gagggttgcc atagaaagcc atggcaatta gactcatagc ttttttgata
    58861 tcagtgacca aaacaacggg aataccaagc tcgtaatcta cctctgaaat atagagttgt
    58921 aatccgttag tgattgcttc tttaaggtag tcagctttga aagttgcccc tttagcaaaa
    58981 aaaagggtct tgccatctac ttgacggcta tcgtaactca agcgctcaaa actaaagcct
    59041 tgataatggt agtggtatcc gtcggcatca agaacctcac gaaaattatg gtcttttttt
    59101 aaaatgtcta ataattgttc aatggttatc atacccttat tttatcctta aagttcttgt
    59161 tttacaagtc acaagcaaaa gtttataata aagctaatag aaactaggaa agaatagata
    59221 tgccgacaga aaaaaaacaa ctgacacaag aagaattgat ggttcaggga gcagcctggt
    59281 ccacagctgg taatttcatt agccgacttt tgggagtgtt atacattatt ccctggtata
    59341 tttggatggg gcaatacgcg attcaagcca acgctctttt caatatgggg tataatgttt
    59401 atgcttattt tttattgatt tcaaccacag gactcaatgt tgcgattgct aagcaggttg
    59461 ccaagtacaa ttccatggga caaactgagc atagctatca attaatccga agtaccctaa
    59521 aactcatgct tggtctgggc cttatttttt cagccattat gtatctgggc tctcctttat
    59581 ttgcgagctt atctggtggt gatgacacac ttgttcccat tatgcacagc ctttctttag
    59641 cagtttttat ttttcctgta atgagtgtga ttcgaggcat ctttcaaggc cacaataata
    59701 tcaagcctta tgcagttagt cagattgctg agcaactcat tcgggttatc tggatgcttt
    59761 tgaccacctt ttttatcatg aagttgggtt ctggtgatta cgcttcagca gtgactcagt
    59821 caacttttgc agcctttatc gggatggtgg ctagtatggg tgttctgggg tactatcttt
    59881 ggaaacaggg acttctagca gctattttta gtaagccaga tcatactgtt tccattgata
    59941 tcaagggctt gttgcttgaa accttaaaag aatccatccc ctttatcgta acaggaagtg
    60001 ccattcaagc ctttcaattg attgatcaat ggacttttgt caatactatg actcttttta
    60061 cagattatag ccgttctcaa ttgcttgttt tatttggtta ctttaacgca aacccagcca
    60121 aaattacaat ggttttaatt gcagtagcag catctattgg tggtgtaggc attgccttat
    60181 taactgaaaa ttatgtcaaa aaagatatga aagcagctgc tcgcttaatc attaacaaca
    60241 ttgaaatgtt agtaatgttt ttgttacccg ctcttactgg ggcaattatt ttagcaagac
    60301 ctctatattc tgttttttac ggagctagcg aggatcgtgc cattcacctc tttgtggcgg
    60361 tcctcttcca aaccttgttg atggcgcttt acaccctttt ttcaccgatg cttcaagctc
    60421 tttttgaaaa tcgaaaagcg atttactact ttgcctatgg tatcttgatt aagttagttt
    60481 tacagatacc gcttatttat ttgctacatg cttatggtcc tttactagcg acgacgattg
    60541 ctttagtggt gccgatttat ttgatgtatc gacgcctata tcaggttact cattttaacc
    60601 gcaaactgtt gcaaaaacgt ttattattaa ccttgattga aaccttatta atgggactgg
    60661 tcgtgtttgt ggccaactgg ctattgggct atgtctttaa accgacaggc cgcttgacca
    60721 gccttcttta cctcctcatt attggtggct tgggaatgac ggtttacacg gcactcacct
    60781 tgctgacgca tcaactggat aaattaattg gtagcaaagc tagtcgcctt cgtcagaaat
    60841 taggctggca ttaatataat gacaccaaga acgatttcgt gagtgcttat cgaaatcgtt
    60901 tttttcttaa tgatctcgct tagtaaaggt agccgataaa aaatcaggat ttcccaagca
    60961 aactactgat atttttggta taatgataaa agtgtaaaaa aatagaagga agtatatcaa
    61021 catgggaaaa tgtcaagtta tttcgcatcc gcttatccaa cacaaacttt caatcttacg
    61081 tcgtcaaacc acatcaacta aagattttcg tgagttggtt aatgaaattg cgatgctgat
    61141 gggatatgaa gtgtcacgcg accttccctt agaagatgtc gacatccaaa cgccagtctc
    61201 aaaaacggtc caaaaacagt tagctggtaa aaaattagct attgttccga ttcttcgtgc
    61261 tggtattggg atggttgatg gcttgttaag tttggtacca gctgcaaaag ttggccatat
    61321 cggcatgtac cgtaatgaag aaacccttga acctgttgaa tacctcgtta aattaccaga
    61381 agatattaac caacgacaaa ttttccttgt tgatccaatg ttggcaacag gtggctcggc
    61441 tatcttagca gtggattcgt tgaaaaaacg tggtgcagca aatattaagt ttgtctgttt
    61501 agttgcagca ccagaagggg tgaaaaaact tcaagaagct catccagata ttgatatctt
    61561 cacagcagca cttgatgatc atttaaatga acatggctat atcgtgccag gcttgggcga
    61621 tgctggtgat cgtttatttg ggacaaaata aaagagacaa ccatcaaata gtagcctttt
    61681 taggccaatc gttcttgatt ttgtttaaaa aatcagagag atttctcttc tttaaaggaa
    61741 aagcaagttt atgatttgac ctttattgac caaaatatta taataaagac aatcagtaaa
    61801 aaagagatga cctagtgggt tgccgtctct caaaatgacg ctactaaaaa cccttgtaga
    61861 ttggagaatg tattatgatt cctgttgtta ttgaacaaac tagtcgtgga gaacgttctt
    61921 atgacattta ttcacgttta ttaaaagacc gtattatcat gttaacaggg cctgtcgaag
    61981 acaacatggc caactctgtc atagcgcagc tcttattcct tgacgcgcaa gacaacacta
    62041 aagatatcta cctatatgtc aacacaccag gtggctctgt ctcagcaggc ttggctattg
    62101 tcgataccat gaactttatc aaggccgatg tgcaaactat tgtcatgggt atggcagctt
    62161 ctatggggac agtcattgct tcatcaggaa caaaaggcaa acgctttatg ttaccaaatg
    62221 cagagtatat gatccaccag ccaatgggtg gcacaggcgg tggcacgcaa caaacggata
    62281 tggctatcgc agcagaacat ctcttaaaaa cacgtcaccg tttagaaaaa atcttagcgc
    62341 aaaatgctgg aaaaacgatt aaacaaatcc ataaagatgc tgagcgtgat tattggatga
    62401 gtgctgaaga aaccttggct tacggtttca ttgatgaaat catggaaaac aacgaactaa
    62461 aataaagaag atctctgcaa aagtattcta gaaacttcta ggatgctttt tctcttagaa
    62521 aggaaaataa tgatacagcc tactgcatta aaacagcttc aagagttaaa acgtcagttc
    62581 agatcccttt gcaaccaatt atgagatagt ttgaggatga tccttagcag ctgtgtgcac
    62641 gaagttatga cgatttcata aaggatgacc tagctagtct ttcttcgtct cttttactta
    62701 aagtgtggta taatcagatt atgctagcca aaattaaaaa aggcattgcc attaaaggtg
    62761 ttgtagatcg gcttatccta gatctcataa caatgctgta gtacggccct taccttgcta
    62821 ctaaagacgc tgttgaagca caaattgact tgcaaaggat cttgactgat aggtatatgt
    62881 ccggtggaat cgccaaagca gcaaaaagac caagaccctt atttggtctc taccaaaata
    62941 taatagaaaa ggatttagaa tgtttcaaaa acaagaacgt attggactcg tcgtttacct
    63001 gtattataac cgagatgcca gaaagttatc aaaatttggt gatttatatt accattccaa
    63061 gcgctctcgt tacctcatta tttatattaa taaaaatgat ttagacacaa aattagaaga
    63121 aatgagacgt ttgaaatgtg ttaaagacat tagaccatca gcttttgatg atattgaccg
    63181 ccaatttgta ggtaaccttc atcgcgacga aacaaacaac catcaaaagg gttaacaacc
    63241 ccctagttac tgattagcgt ttcagattta gttagcttat taaagtaaga aggttttgac
    63301 agatgctcac actacttcaa gacaatgaga caactagagc attagtgaat aactgagttg
    63361 actgtcactt ctttaataag aacggatagg attggtccta aaatagagca ctgcaaagat
    63421 atgccagtgc tttttagctc attttttgat aaaatagaac tactaaaaag tgaaggaaat
    63481 aagatgatca caggaaaact cataaccgtt gaaggtccag atggcgcagg gaaaacgact
    63541 gttttagagc aactcattcc actgttaaaa caaaaagtgg ctcaggatat cttgacaaca
    63601 agagagcctg gaggtgttgc catttcagaa cacattagag aacttatttt agacatcaac
    63661 catactgcta tggaccctaa aacagaactc ttactttata ttgcggctcg aaggcagcat
    63721 ttggtggaaa aggtactacc agctcttgaa gcaggccagt tggtttttat tgatcgtttc
    63781 atcgatagtt cagtagctta tcaaggtgcg ggacgcggtt tgatcaaagc agacattcag
    63841 tggctcaacg agttcgcaac agatggttta gagcctgact tgacccttta ttttgatgtt
    63901 ccttctgaaa ttggtttagc acggattaac gcgaaccaac aaagagaagt caatcgttta
    63961 gatttggaaa caatagagat acatcaacga gtacgaaaag gatacctagc cttagctaag
    64021 gagcatccaa aacgtattgt cacaattgat gcgactaaac cattgaaaga agttgtctct
    64081 gtcgctttgg aacatgtctt agccttgctt ttagcctagg ataagggagg gtaggaatgg
    64141 atttagcgca aaaagctcct aacgtttatc aagcttttca gacaatttta aagaaagacc
    64201 gtctgaatca tgcttatctt ttttcgggtg attttgctaa tgaagaaatg gctctttttt
    64261 tagctaaggt catcttttgt gaacagaaaa aggatcagac gccctgcggg cattgtcgct
    64321 cttgtcaatt gattgaacaa ggagattttg ccgatgtgac ggtattggaa ccaacagggc
    64381 aagtgattaa aacggatgtg gtcaaagaaa tgatggctaa cttttctcag acaggatatg
    64441 aaaacaaacg acaagttttt attatcaaag attgtgacaa aatgcatatc aatgccgcta
    64501 atagcttgct aaagtatatt gaggagcctc agggagaagc ttacatattt ttattgacca
    64561 atgatgataa caaagtgctt ccgaccatta aaagtcggac acaggttttt cagtttccta
    64621 aaaacgaagc ctatctttac caattggcac aagaaaaggg attattaaac catcaggcta
    64681 agttagtagc caaacttgcc acaaacacca gtcatctaga acgtctgttg caaacgagca
    64741 agcttttaga actgataact caagcagagc gttttgtatc tatttggctg aaagatcagt
    64801 tgcaggcata tttagcgttg aatcgtctgg tacagttagc aactgaaaaa gaagaacaag
    64861 atttagtttt gacccttttg accttgctct tggcaagaga gcgtgcgcaa acgcctttga
    64921 cacaattgga ggctgtctat caggctaggc tcatgtggca gagcaatgtt aattttcaaa
    64981 acacattaga atatatggtg atgtcagaat aagtgcaatt ggaattcgtt atggggaaac
    65041 gaagcttgtc aaaagacttg cccgtagcga ccaaaatagc ggcgcatagg ggcaaaaaag
    65101 cttttgaaga aaatactgcc tttgcaacag atttgatgaa agaagtatca cgattaataa
    65161 cacaaaatca acttgaaatg acgtttatta atagtgtctt tctcttagat cagcatgttg
    65221 tcctaattcc cttttcagca gaagagcaca tggattttta caactgttaa aagatttagc
    65281 ggtcgatttt aggttaagaa gtgagctgcc ccagattaac agccaagaag atttcatttt
    65341 ctatggaggc tatggaccgt gtggcaggcc actgtgctgc tttcgttttt gggaaaattt
    65401 ctgacagtat ctattaaaat actaaaaagt caagggttat cattgacttt gggtaaagca
    65461 gcaagccctt atggccgttt gctttgctgt ctctatgatg aaggtggctt ctaccaataa
    65521 agcaagaaaa aattccctga atatggtacc atagtagaga caagtgatgg cactgcaaca
    65581 gtagcagccg ttgatatatt tacagatccc attaaggtgc ggttaaaaga ccagttgacc
    65641 ttagtcactt atgctttaga ggaggttaaa gtaggtgaat aaaaaagaat tattcgatgc
    65701 ttttgatgga ttttcccaaa atttaatggt tactttagct gaaattgaag ccatgaaaaa
    65761 acaagtccaa tcactagtag aagaaaacac gattcttcgc ctagaaaata caaaactacg
    65821 ggaacgtttg agtcacctag aacatgaaac ggtagctaaa aatccttcca aacaaaggaa
    65881 ggatcactta gagggaattt atgatgaagg gtttcatatc tgcaattttt tctatggaca
    65941 acgtcgtgaa aatgatgaag aatgtatgtt ttgcagagaa ttattagata gaaagtaagg
    66001 gcatgcaggt tcaaaaaagt tttaaagaca aaaaaacaag cggaaccttg tatttggttc
    66061 caaccccaat tggcaatctg caggacatga cctttagagc agtggcaacg ttaaaagagg
    66121 ttgattttat ttgtgcagaa gacacaagaa acacaggtct tttgctaaaa cactttgaca
    66181 ttgctaccaa gcaaatcagc tttcatgagc acaacgccta tgagaagatt cctgatttaa
    66241 ttgatttatt aatatcagga cggtcactag ctcaggtgtc tgatgcagga atgccatcga
    66301 tttctgatcc tgggcatgat ttggtcaagg ctgctattga tagtgatatc gcagtcgttg
    66361 ctttaccagg tgcctcagca gggattacag ctttgattgc tagtggactg gctcctcaac
    66421 cccatgtttt ttatgggttt ttacccagaa aagcagggca acaaaaggct ttctttgagg
    66481 acaaacacca ttacccagag acacaaatgt tttatgaatc accctatcgc atcaaagata
    66541 ccctgaccaa tatgttggct tgttatggtg atcgtcaagt ggtgcttgtc agagaattaa
    66601 ccaagctttt tgaggagtac caacgggggt cgatttcaga aatcttgtcc taccttgagg
    66661 aaacacccct caaaggggag tgtctgctga ttgtggctgg agcccaagca gacagtgagg
    66721 ttgagctgac agctgatgtt gacttagtgt ctctagtgca aaaagaaatt caagcaggag
    66781 ccaagccaaa tcaggctatt aaaacaattg ctaaagctta ccaggtaaat cgccaagagc
    66841 tttaccaaca atttcatgac ttataagtca tcgtagatta ggagaaaaac aaatgacaga
    66901 agatcaagca actatcctta ttttaggagt atacggaatc atattggctg tattcttatt
    66961 atcagcttta ttatgcctta tcgctaactg gcgactcttt aaaagagcag gttacaaagg
    67021 atggtatagt ctcattcctt tctatgcagg ttttgtcaaa cacaaaatca cttttggaga
    67081 agataataaa tggttttact ttattggttg ggtcattgct atttattatt actatgtgca
    67141 cttttgctat gtccgtgctt ttggtggatc aaagggtcta gcagtatttg gcttgttttt
    67201 cccaggcatt gcttctttga tagtggcttt tggaaaaact tataccacac aagaatgcca
    67261 ccctgtgcca catcttttaa actaagagaa aaaagaccat caattggatt tattgatggt
    67321 cttttaggtg tttaaatgat tttagtcccg tgaacaatgg ccgttccagt gagttgactc
    67381 aagctttggc aattctcagc agtgatgcct cccccaatca tgatttcaat gcgtttattg
    67441 gcataggtca caagactttt aagctgttcc acattgtctg taataggagt agcttcaggt
    67501 gagccatgag ttagcacacg cacaaagcca taatcaatca gttggtcaag cgcttggtgc
    67561 tggtgatcag tcggaatatg gtcaaaagcc atgtggaaaa ccagtggcaa gccttgtgta
    67621 gcaggcagta attgctcgat agcgtcggta tccagttgat tttctgtggt cagcaagcct
    67681 aagactagcg catctgagcc agcttcaaca gcttttaaga tatcttcttc catagctttt
    67741 agttccaggt cgttatagac aaaatcgcca ccgcgaggtc gaatcatggt cgctacgcta
    67801 atctttttat cgtgtaagag ctgacaggct tctttgatga cgccataaga tggcgtggtc
    67861 cctccgacag ctaggttatc acagagttcc acacgactga cttgaccagc atcaagggtt
    67921 ggcagtagtg tgaggttctc agcacaaaat tctttaatca tttttagttc tcctttatca
    67981 ctaatattat agcacgaatg aagctagtca tcaggaaaca tttttgtcaa atcatggaca
    68041 ttatgctata ctcactagta ttaaaagtag gccaaaacag cagcaaatac tttgaaaaaa
    68101 gcttgctatg ttctacggca atatcagtct ttaccaacga actctcaaga agaaaagaaa
    68161 gacaaagctt agcattttaa aaaagccccc cctttttttg tgaaatgatg accaaaaaca
    68221 ggcgcctcac gcctaaaaca gttaccctaa aggagaaaaa atgattacga tttaccaata
    68281 cccaaaatgt agcacctgcc aaagagccat ggctgaatta aagcaactgg ttagtgactt
    68341 tgaagccatt gacatcaaag ctaatccacc caaagctcag gacctcaaac attggatgga
    68401 aacatctggt tataccatca aaaatttctt taataccagt ggtaacagct accgcgaatt
    68461 gggacttaaa gataaaatag accagcttag ccttgataaa gctgctgaac tcttagccac
    68521 agatggtatg ctgattaaac ggcctattct gattaaggac ggtaaagtcc tacaagttgg
    68581 ctatcgcaag ccatatcaag agttggattt aggataatgc gacaaagtct caaaaaagga
    68641 caaggcaaca ttataacgcc ttgtcctttt ttgggatctg tttttagaca ttagagatca
    68701 atatctagta aaattggcgt atggtcttgg cgttccccag aagaaatcat ttcagaacgc
    68761 ttaaccttat ccacgattcg gtttgaagct aggcaatagt caattctcca accggtatta
    68821 ttgattttgc tggttttgct acgttgtgcc caccaggtat aaacatgagg aatatcgccg
    68881 tgcaagtgac gaaaagtatc tgtaaagcct cttgctaata ggttagtaaa gccttgacgt
    68941 tcttcgtcgg taaaaccagg ggaacgtcga ttgctgcttg gatttgccaa atcaatctct
    69001 ttgtgggcaa cgttgtaatc tcccgtagcc aaaacaggct tttgagtatc aagttcagtc
    69061 aagtaatcag cgtatttgtg gtcccaaatt tgacggtcat ctaaacgtct aaggccatca
    69121 ccagcattag gcgtgtaaac ctgtgtgacg aaaaagtctt caaattctag ggtaatgata
    69181 cggccctcag catccattgt tgttggggca ccaatttctg gaaaagtaat gacagggttt
    69241 aacgtgtttt tgtacaggaa catggtgcca gcatagcctt tcctagcagg ctcaactgaa
    69301 gaacgccaca catgcaaata gtttggaaag taactaagta gggtctcgat atgttttttg
    69361 gaaggccctt tagcagataa tttggtttct tgaatggcaa taatatccgc atcttgagcg
    69421 actaaagtgt ctaaaacagc gcgtgataaa agcgcacgag gggactctcc tgtgagagca
    69481 gcatttaagg aatcaatgtt ccatgaaatc agtttcattt ggtttctctt tctaacagat
    69541 agtcttgttg ttattgtaac aaaaaacgaa acgataagcg actttgggca cctagccccc
    69601 ataaaacagt ctagccaaat gaagcatagc agcgtaagaa caagacaagg aggtgatcag
    69661 tgagcatatc gtttgacagt taagagtagg attactataa tagaaacata aatgtaagcg
    69721 ctaacaaaat aaaaaaatat aggagaatgt caatggcaca aaaaacagtc atcaccgaag
    69781 aaacaaccga ttttgttatg gatttcaaaa caagtagcgc tgagggaaat gttgatttta
    69841 ttaacgtttt tgaccttgag aaaatggcac aacaggtcat ccctaaagga gcctttggtt
    69901 atattgctag tggtgctggt gataccttta ccctccatga aaatattcgc tcatttaatc
    69961 ataaattaat tgtccctcac tccctcaaag gggttgaaaa tccgtcaaca gagattacgt
    70021 ttgatggtga tcacttaacc tctcctctta ttttagcacc tgtagcggct cataaactgg
    70081 ccaatgaaca aggagaagta gcgtctgcta aaggattgaa ggaatttgga agtatctaca
    70141 ccactagttc ctactcaaca actgacctgc cagaaatcag tgctgcctta ggtgggacac
    70201 cccattggtt tcaattttat tacagtaaag acgatggcat taatcgtaat attatggatc
    70261 gtgtcaaagc acaaggttgc aaagctatcg ttttgacagc agatgcaaca gttggaggaa
    70321 accgcgaagt tgataggcga aacggttttg tttttccggt cggtatgcca attgttcaag
    70381 aatatttacc tgatggtgca ggtaaaacaa tggattatgt ctataaatca gctaaacaag
    70441 cgcttacctc aaaagatatt gaatatatcg caacttactc aggcctgcct gtttatgtca
    70501 aaggaccaca gtgtgctgag gataccttgc gggcattgga cgcaggagca tcaggtatct
    70561 gggtaaccaa tcatggtggc cgtcaattag atggtggtcc agctgctttt gattccttac
    70621 aagaagtcgc tgaagcagtt gatcaaaaag ttcctattgt ctttgactca ggtataagac
    70681 ggggtcaaca tattttcaaa gctcttgctt caggtgctga ccttgttgcc ttggggcgtc
    70741 cagcaattta cggcttggct atgggaggaa gcactggtac tcgtcaggtc tttgaaaagt
    70801 taaatgacga gttaaaaatg gtcatgcaac tggctgggac acagactatc caagatgtta
    70861 aagcctttaa ccttcgccac aatccgtatg attcatcgat tccatttgat caaaatgcgt
    70921 tacgcttaga ttagaacaga caaaaacctc cgctatcatg tcacaaatag tagaggtttt
    70981 acactgcaaa aagaggtatg aaaatccaat aacatagtta caaggttttc gtttaccccc
    71041 cactaataga ttaaaatgaa agacttctta cattaataga aatttctgtt gcttttctca
    71101 gaaaaatgtg gttaaataat caaatattat taacgaaaaa tgagttaatg attaacatta
    71161 aactggtttt agttaaaaca tttaggaggg tatcaggtgg agaaaaagca acgtttttcc
    71221 cttagaaaat acaaatcagg aacattttcg gtcttaatag gaagcgtttt cttggtgatg
    71281 acaacaacag tagcagcaga tgagctaagc acaatgagcg aaccaacaat cacgaatcac
    71341 gctcaacaac aagcgcaaca tctcaccaat acagagttga gctcagctga atcaaaatct
    71401 caagacacat cacaaatcac tctcaagaca aatcgtgaaa aagagcaatc acaagatcta
    71461 gtctctgagc caaccacaac tgagctagct gacacagatg cagcatcaat ggctaataca
    71521 ggttctgatg cgactcaaaa aagcgcttct ttaccgccag tcaatacaga tgttcacgat
    71581 tgggtaaaaa ccaaaggagc ttgggacaag ggatacaaag gacaaggcaa ggttgtcgca
    71641 gttattgaca cagggatcga tccggcccat caaagcatgc gcatcagtga tgtatcaact
    71701 gctaaagtaa aatcaaaaga agacatgcta gcacgccaaa aagccgccgg tattaattat
    71761 gggagttgga taaatgataa agttgttttt gcacataatt atgtggaaaa tagcgataat
    71821 atcaaagaaa atcaattcgg ggattttgat gaggactggg aaaactttga gtttgatgca
    71881 gaggcagagc caaaagccat caaaaaacac aagatctatc gtccccaatc aacccaggca
    71941 ccgaaagaaa ctgttatcaa aacagaagaa acagatggtt cacatgatat tgactggaca
    72001 caaacagacg atgacaccaa atacgagtca cacggtatgc atgtgacagg tattgtagcc
    72061 ggtaatagca aagaagccgc tgctactgga gaacgctttt taggaattgc accagaggcc
    72121 caagttatgt tcatgcgtgt ttttgccaac gacgtcatgg gatcagctga atcactcttt
    72181 atcaaagcta tcgaagatgc cgtggcttta ggagcagatg tgatcaacct gagtcttgga
    72241 accgctaatg gggcacagct tagtggcagc aagcctctaa tggaagcaat tgaaaaagct
    72301 aaaaaagccg gtgtatcagt tgttgtagca gcaggaaatg agcgcgtcta tggatctgac
    72361 catgatgatc cattggcaac aaatccagac tatggtttgg tcggttctcc ctcaacaggt
    72421 cgaacaccaa catcagtggc agctataaac agtaagtggg tgattcaacg tctaatgacg
    72481 gtcaaagaat tagaaaaccg tgccgattta aaccatggta aagccatcta ttcagagtct
    72541 gtcgacttta aaaacataaa agatagccta ggttatgata aatcgcatca atttgcttat
    72601 gtcaaagagt caactgatgc gggttataac gcacaagacg ttaaagataa aattgcttta
    72661 attgaacgtg atcccaataa aacctatgac gaaatgattg ctttggctaa gaaacatgga
    72721 gccctgggag tacttatttt taataacaag cctggtcaat caaaccgctc aatgcgtcta
    72781 acagctaatg ggatggggat accctctgct ttcatatcgc acgaatttgg taaggccatg
    72841 tcccaattaa atggcaatgg tacaggaagt ttagtgtttg acagtgtggt ctcaaaagca
    72901 ccgagtcaaa aaggcaatga aatgaatcat ttttcaaatt ggggcctaac ttctgatggc
    72961 tatttaaaac ctgacattac tgcaccaggc ggcgatatct actctaccta taacgataac
    73021 cactatggta gccaaacagg aacaagtatg gcctctcctc agattgctgg cgccagcctt
    73081 ttggtcaaac aatacctaga aaagactcag ccaaacttgc caaaagaaaa aattgctgat
    73141 atcgttaaga acctattgat gagcaatgct caaattcatg ttaatccaga gacaaaaacg
    73201 accacctcac cgcgtcagca aggggcagga ttacttaata ttgacggagc tgtcactagc
    73261 ggcctttatg tgacaggaaa agacaactat ggcagtatat cattaggcaa catcacagat
    73321 acgatgacgt ttgatgtgac tgttcacaac ctaagcaata aagccaaaac attacgttat
    73381 gacacagaat tgctaacaga tcatgtagac ccacaaaagg gccgcttcac tttgacttct
    73441 cgctccttaa aaacgtacca aggaggagaa gttacagtcc cagccaatgg aaaagtgact
    73501 gtaagggtta ccatggatgt ctcacagttc acaaaagagc taacaaaaca gatgccaaat
    73561 ggttactatc tagaaggttt tgtccgcttt agagatagtc aagatgccca actaaataga
    73621 gtaaacattc cttttgttgg ttttaaagga caatttgaaa acttagtagt tgcagaagag
    73681 tccatttaca ggttaaaatc tcaaggcaaa accggttttt actttgatga atcaggtcca
    73741 aaagacgata tctatgtcgg taaacacttt acaggactcg tcactcttgg ttcagagacc
    73801 aatgtgtcaa ccaaaacgat ttctgacaat ggtctacaca cacttggcac ctttaaaaat
    73861 gcagatggca aatttatctt agaaaaaaat gcccaaggaa accctgtctt agccatttct
    73921 ccaaatggtg ataacaacca agattttgca gccttcaaag gtgttttctt gagaaaatat
    73981 caaggcttaa aagcaagtgt ctaccatgct agtgacaagg aacacaaaaa tccactgtgg
    74041 gtcagcccag aaagctttaa aggagataaa aactttaata gtgacattag atttgcaaaa
    74101 tcgacgaccc tgttaggcac agcgttttct ggaaaatcgt taacaggagc tgaattacca
    74161 gatgggcatt atcattatgt ggtgtcttat tacccagatg tggtcggtgc caaacgtcaa
    74221 gaaatgacat ttgacatgat tttagaccga caaaaaccgg tactatcaca agcaacattt
    74281 gatcctgaaa caaaccgatt caaaccagag cccctaaaag accgtggatt agctggtgtt
    74341 cgcaaagaca gtgtctttta tctagaaaga aaagacaaca agccttatac agttacgata
    74401 aacgatagct acaaatatgt ctcagtagca gacaataaaa catttgtgga gcgacaagct
    74461 gatggcagct ttatcttgcc gcttgataaa gcaaaattag gggatttcta ttacatggtc
    74521 gaggattttg cagggaacgt ggccatcgct aagttaggag atcacctacc acaaacatta
    74581 ggtaaaacac caattaaact taagcttaca gacggtaatt atcagaccaa agaaacgctt
    74641 aaagataatc ttgaaatgac acagtctgac acaggtctag tcacaaatca agcccagcta
    74701 gcagtggtgc accgcaatca gccgcaaagc cagctaacaa agatgaatca ggatttcttt
    74761 atctcaccaa acgaagatgg gaataaagac ttcgtggcct ttaaaggctt gaaaaataac
    74821 gtgtataatg acttaacggt taacgtatac gctaaagatg accaccaaaa acaaacccct
    74881 atctggtcta gtcaagcagg cgctagtgca tccgctgttg aaagtacagc ctggtatggc
    74941 ataacagccc gaggaagcaa ggtgatgcca ggtgattatc agtatgttgt gacctatcgt
    75001 gacgaacatg gtaaagtaca tcaaaagcag tacaccatat ctgtgaatga caaaaaacca
    75061 atgatcactc agggacgttt tgataccatt aatggcgttg accactttac tcctgacaag
    75121 acaaaagccc ttggctcatc aggcattgtc cgcgaagaag tcttttactt ggccaagaaa
    75181 aatggccgta aatttgatgt gacagaaggt aaagatggta tcacagttag tgacaataag
    75241 gtgtatatcc ctaaaaatcc agatggttct tacaccattt caaaaagaga tggtgtcaca
    75301 ctgtcagatt attactacct tgtcgaagat agagctggta atgtgtcttt tgctaccttg
    75361 cgtgacctaa aagcggtcgg aaaagacaaa gcagtagtca actttggatt agacttaccg
    75421 gtccctgaag acaaacaaat agtgaacttt acctaccttg tgcgggatgc agatggtaaa
    75481 ccgattgaaa acctagagta ttataataac tcaggtaaca gtcttatctt gccatacggc
    75541 aaatacacgg tcgaattgtt gacctatgac accaatgcag ccaaactaga gtcagataaa
    75601 atcgtttcct ttaccttatc agctgataac aacttccaac aagttacctt taagatgacg
    75661 atgttagcaa cttctcaaat aactgcccac tttgatcatc ttttgccaga aggcagtcgc
    75721 gttagcctta aaacagctca aggtcagcta atcccgcttg aacagtcctt gtatgtgcct
    75781 aaagcctatg gcaaaaccgt tcaagaaggc acttacgaag ttgttgtcag cctgcctaaa
    75841 ggctaccgta tcgaaggcaa cacaaaggtg aataccctac caaatgaagt gcacgaacta
    75901 tcattacgcc ttgtcaaagt aggagatgct tcagattcaa ttggcgatca taaggttatg
    75961 tcaaaaaata attcacaggc tttgacagcc tctgccacac caaccaagac aacgacctca
    76021 gcaacagcaa aagccctacc atcaacgggt gaaaaaatgg gtctcaagtt gcgcatagta
    76081 ggtcttgtgt tactcggact tacttgcgtc tttagccgaa aaaaatcaac caaagattga
    76141 taacaaaacg caaagagaca acaaatcatc ccttttaaca gtctgacctt tctttgagat
    76201 tgagctggca gatgatcatt tcttaacaaa agttaaagag ttgagcaaag taaggaacag
    76261 acataaacac cataaaagca agccaaactg gcttgctttt atggtgttat tgtcgtgtgc
    76321 tacgatgact aaaaaagaac aacgaacaat gacctcgaat caccaaaagg acttgatttg
    76381 atagcttccc tatgctatgc tatactaagc ctattctttc aagaaggact ccttttgtgg
    76441 aaaagactga aaaaaaggac actaatctat ccaaaaactc cagataggta gctgcaaacg
    76501 gatgcctctg ctgtgatcaa ggggataaag cagactggct tgtcactacc tgagcaggtg
    76561 tcaaaaaaag aagcttttgg ctttgacatt caacatactg agctttagta ttttagaacg
    76621 gagacacccc cagttttgta ctcaaaaagc atgaacagct ctgctgatgt gacatctgat
    76681 ttctacgtgc gcagtgagcc aaaacagctg ctgtttgcta tggaaaaagt ggcgccaatc
    76741 gagatttttg agaccctagg ctcaaaaata aggcatagaa ttccaaagga agtcgctgcc
    76801 gtgagcacaa cctaagaaaa actattccaa aagacttttt ctgcaatttg aaatactgaa
    76861 tttcagtatt ttttcttttg taactaagag caatgaatga ggtaaaaaaa ggcaacaatg
    76921 tcaaaaaaga aacgaaaaca ctatcaggtt tatgagggat tacgctgtgc tatgacgctt
    76981 tgttttatca gtggctatgt caatgccttt acctatatga cccaaggcaa acgttttgca
    77041 ggtgttcaga caggcaacct tttgtcattt gccattcgct tgtcagaaca gcaactgaag
    77101 gaggcactgc aatttttact tcccatgctc gtttttatgc ttgggcagtc ctttacttat
    77161 ttcatgcacc gctgggccac taaaaaaggg ctccactggt acctcttatc aagcgttatc
    77221 ttaacaggga ttgcttttgg aacggcccta ttcacgcctt ttcttccttc caatgttacg
    77281 gtagcagctt tagccttttt tgcctctatt caggttgata cgtttaaaac cttacgagga
    77341 gctagctatg ctaatgtgat gatgacagga aatatcaaaa atgccgccta tttactaacc
    77401 aaaggcttgt acgaaaaaaa ttacgaacta acacatatcg gacgcaacac cttaatagtc
    77461 atcttggctt ttgctgttgg ggtggtttgt tcgacgttgc tttgcatagc ttatggcgag
    77521 tatgctttga tgcctatttt aatgccttta ctctatgtca attacctgtt ggctcaggaa
    77581 ttttatcaca ttcaaaccaa aatcaaaccg attaaaagaa cttaacggac ttgtggagaa
    77641 agaaagttca tttagagtaa gtttttactt accctccgtt gatttcctgg ttttgctgcc
    77701 ccttaaaata tgatataata gaccattaat agctgttact taacagaagg ctgataaaaa
    77761 aggttccatt agccttgagg gttgaattta aacaggaaaa aacgaaatcc tacactatgc
    77821 atctcaatcg tactttcatt tgagtatggt tctgaaagga aactatgatg aaaaaaccat
    77881 tttacattac gacacccatt tattacccat ctgggaaatt acacattggt tctgcctata
    77941 caactattgc ttgtgatgtc ttggcacgct acaagcgctt gatgggccat gaggtctttt
    78001 acctcacagg acttgatgag cacggacaaa agattcaaac caaggcaaaa gaagctggta
    78061 ttacacctca aacctacgtt gataacatgg caaaggatgt caaagccctt tggcaattgc
    78121 tagatatttc ctatgacaca tttatccgga caacggacga ttaccacgaa gaggtcgttg
    78181 ctgctgtctt tgaaaaattg ctggcgcaag atgatattta ccttggcgaa tactctggtt
    78241 ggtattctgt ctctgatgag gaatttttca ctgaaagcca attaaaagaa gtctttagag
    78301 atgaagacgg tcaggttatt ggagggattg ccccatcagg tcatgaggtc gagtgggtct
    78361 ctgaagaatc ctacttccta cgccttagta aatacgctga tcgtcttgtg gccttcttta
    78421 aagagcgacc tgactttatc caaccagatg gtcgtatgaa tgaaatggtg aaaaacttta
    78481 tcgagccagg cctagaagat ttggctgtta gccgtactac ctttacatgg ggtgtacctg
    78541 ttccatcaga cccaaaacac gtggtttatg tctggatcga tgccctctta aattacgcga
    78601 cagctcttgg ttatggtcaa gctaatcacg ctaactttga taaattctgg aatggaacgg
    78661 ttttccacat ggttggaaaa gatatcttgc gttttcatag catctactgg ccaattttac
    78721 tcatgatgct tgatttacca atgccagacc gcttaattgc tcatggttgg tttgtcatga
    78781 aagacggtaa aatgtctaaa tcaaaaggca atgtggtcta tccagaaatg ttagtagagc
    78841 gctttggact ggatcctctt cgttattacc tcatgcgttc tttgccagtt ggttcagacg
    78901 gtacctttac ccctgaagat tatgtgggtc gtatcaacta tgaattggcc aacgaccttg
    78961 gcaatttatt gaaccgtacc gttgccatga tcaacaagta ttttgatggc acggtgccag
    79021 cttatgttga caatggaact gcctttgatg ctgacttaag tcaactgatt gatgctcagc
    79081 tagcagacta ccataagcac atggaagctg tagattaccc acgcgccttg gaggctgttt
    79141 ggaccatcat cgctcgtacc aacaaataca tcgatgaaac cgctccttgg gtgctcgcta
    79201 aagaagatgg tgacaaggct caactagcca gtgtcatggc acacttggca gctagcttgc
    79261 gcgtggtcgc tcatgtgatc caacccttta tgatggaaac atcagctgct atcatggccc
    79321 agcttggttt ggaacctgtt tctgatttgt caacacttgc tctagcagat tttcctgcca
    79381 atacaaaggt tgttgccaaa gggacaccga ttttcccacg tcttgacatg gaagctgaga
    79441 ttgactacat caaagcccaa atgggtgaca gctcagctat ttcccaagaa aaagaatggg
    79501 tccctgaaga ggttgcgctc aaatctgtaa aagacgtcat cacatttgaa acctttgatg
    79561 ctgtggaaat ccgtgtggca gaagtcaagg aagtgtcaaa agtggaaggt tcagaaaaat
    79621 tgctgcgctt tagagtagat gcaggagacg ggcaagaccg tcaaatcttg tcaggtattg
    79681 ccaaatttta ccccaacgaa caagaattag tgggcaaaaa actacaaatt gttgctaacc
    79741 tgaaaccgcg taaaatgatg aaacaataca tcagccaagg catgatttta tcagcagagc
    79801 atggagatca gctaacggtc ttaaccgttg attcctctgt tccaaatgga agtatcattg
    79861 gctgatgctg acctattatt caaaaaacct aagcaagaac atgtgcttag gtttttttga
    79921 ttgccttcaa gaaagacgaa taacgagatg ggtgatatga catcaaaagc ataactatcc
    79981 taggacctgt cctagtaata ttgctgtgct tttgacaagt gaacagagag gtcttaaaac
    80041 tatatcttgt cataaaaaag attgcaaaac actatatctt gtgttattat ggtttttata
    80101 aaagttaagc gtgcttaact ttagccaaac aaaagaggac actagagcgt gtcccacaag
    80161 acagttgagc ccttcgcttt tttagtagag taggagtgct caagtcaaaa agagacatcc
    80221 catcaaacca ttgctgttta gcaggtcttt ttgtgttgct caaaaaaaca attcctgtct
    80281 gtttggcgtc tagtgatgac ttaggcttag cgctactaga cttttgtttg aaaaatacct
    80341 caagccttga aggagacaaa tgacccaaca ttattatgaa cgttcgcaat ccccaattga
    80401 atacgcccta tctgaaacac aaaaacagtt gcgctccatc aattggaatt accttaatga
    80461 tgacaaagat ttggaagtgt ggaaccgtgt cactcaaaat ttttggttgc ctgaaaaggt
    80521 tcctgtttct aatgatttaa attcttggcg ctccttgggt gaggattggc aacagctcat
    80581 cacaaggacc tacactgggt tgactttact agatacagta caagcaacgg ttggtgatgt
    80641 ggcacaaatt cagcattcac aaaccgacca cgaacaagtc atctatacga actttgcctt
    80701 tatggtgggg atccatgccc gctcttacgg gacgattttt tcgacccttt gcagcagcga
    80761 gcaaatcgaa gaagcacatg aatgggtggt ctcaacacag agcttgcaag accgtgcccg
    80821 cgtcttgatt ccttactata cgggtgatga ccctctgaaa tcaaaagtag cagcagctat
    80881 gatgccagga tttttgctgt atggcggctt ttaccttcct ttttacctat cagcacgtgg
    80941 taaaatgcca aacacatctg atatcatccg cctgatttta cgcgacaaag ttattcacaa
    81001 ctattacagc ggttacaaat accaacaaaa agtagcacgt cttagcccag aaaaacaggc
    81061 tgaaatgaag gcctttgtct ttgacttgct ctatgaactc atcgatcttg aaaaagctta
    81121 cttgagagaa ctgtatgcag gctttgattt ggcagaagat gctatccgct ttagccttta
    81181 taacgctgga aaattccttc aaaatttagg ctatgagtcg cccttcacag atgaagaaac
    81241 gcgcgtttca ccagaagttt ttgctcagct atcagcgcgt gcagacgaaa accatgactt
    81301 tttctcaggc aatggctcat cttatgtgat ggggatcacc gaagaaacca cagatgacga
    81361 ttgggagttt taagaaatgg cagagctgat tattgtgtat ttttcatcta agtccaataa
    81421 cacccatcgc ttcgtccaaa aattaggcct gcctgctcag cgcataccag tagataatag
    81481 gccacttgaa gtttcaaccc attacctttt gattgtgcct acctatgcag ctggtggctc
    81541 agatgccaaa ggagccgttc ctaaacaagt gattcgtttt ttgaataatc ctaacaatcg
    81601 taaacattgt aagggagtga tctcttcagg aaataccaat tttggcgata cctttgccat
    81661 tgcaggacct atcatttctc aaaaattgca ggtcccccta ttacaccaat ttgaactatt
    81721 aggcactgct acagatgtca aaaaggtaca ggcgatcttt gcccgcttaa agcatcacac
    81781 acacgacaag caaaaacaaa ccaacaacct gattacagaa aggacacacc catgtcacaa
    81841 accaatgcgt catacctctc attaaatgca ctgacccgtt ttaaaaaacc agacggcagc
    81901 taccattttg atagcgataa agaagctgtt aggcgctacc tggaagaaca tgtctctccc
    81961 aatcaaatgg cttttaactc actagaagat aagctagctt acctcatcaa tgaagggtat
    82021 tatgagcagg ccatttttga tgcctatcct aacgacctta tcaaggaggc ttttcattat
    82081 gcctatcaac aaggctatcg ctttttaaat ctcatgggcg ctatgaaatt ttaccagtcc
    82141 tatgccttaa aaaccttgga cggtaagcag tatctagaaa catttgaaga ccgtgctgtg
    82201 atgaatgcac tctttttagc tgatggagat caaacctttg tctttgacgt gattgatgcc
    82261 atcttgcacc gacgctttca accagctacc ccaacctttt taaatgccgg aaaaaaacgc
    82321 cgtggcgaat acatttcgtg ctatcttctt cgtgtcgaag acaatatgga atctatctct
    82381 cgcgccatta gcaccagctt gcaactctca aaaagaggag gcggagtcgc cttgtgcctc
    82441 accaacctca gagaaatcgg agcaccgata aaagggattg aaaatcaggc aacaggcatc
    82501 gttcctgtca tgaaactact agaggactct ttttcctatg ccaatcaact aggtcagcgc
    82561 caaggagcag gtgcggttta ccttcatgcc catcaccctg aggttttgac ctttttagac
    82621 accaaacgtg aaaatgccga tgagaaaatt cgcattaagt ccctagcatt gggacttgtg
    82681 atcccagata ttaccttcca gttagccaaa gaaaacaaag atatggcact cttttcaccc
    82741 tatgatatca agcgtgccta tggcaaggac atgtcagaca tctccatcac agaggaatac
    82801 gataaactgc tagccaatcc agccatcaaa aagacctaca tcagtgctag aaagttcttt
    82861 cagttaattg cagagctaca ttttgagtca ggctaccctt acctcttgtt tgatgacacg
    82921 gtcaataagc gcaaccctca tgccaaaaaa ggcagaatcg tcatgtctaa cctgtgttct
    82981 gaaatcgctc aagtcagcac cccaagcact ttcaaagaag atttgagttt tgaaaccatt
    83041 ggagaggata tctgctgtaa tttagggtct atcaatattg cccaggcaat ggcagatgcg
    83101 ccacactttg aacagctcat cacaacgagc atcagagcac ttgatcgtgt ctctagagtg
    83161 tctgacctga attgtgcgcc ttctgttgag acaggcaatg tagccaacca tgcagtagga
    83221 ttaggcgcca tgaacctaca tgggtttttg gcaaccaacc acatctacta tgatacaaaa
    83281 gaagccgttg actttacaga tctgtttttc catgccatgg cctattatgc ttttaaagcc
    83341 tcttgccaat tagccaaaga aaaaggcgct tttgcaggat tttcgttatc aacctatgca
    83401 gatggcactt attttgccaa gtatttgcaa gaagatgcca agccacaaac agccaaggtt
    83461 gccacattgt tgcaagatta cggcttcaca ttgccaacgg tggcggattg gcaagcccta
    83521 gtagcagata tcaagcagtt tggcctagcc aatgcgcact tgctagcggt tgctccgaca
    83581 ggctccatca gctacttatc atcctgcact ccgagtctac aaccagtcgt tgctcctgtt
    83641 gaggtccgaa aagaaggtag cctgggcagg atttacgtcc ctgcttatca gattgaccag
    83701 gctaactatg cttactatga acgtggtgcc tatgaggtcg gcccaaaagc catcatcgac
    83761 gttgtcgctg ctgcccaaaa gcacgttgac caagccatct cattgaccct gtttatgacc
    83821 gatcaagcga ccacacgtga ccttaaccgc tcctatatcc aagcttttaa gcaaaactgt
    83881 gcatcgatct attatgtgcg agtgaggcaa gacgtcctag caggcagcga acagtatgac
    83941 gaggatagtc ttgtgacagc tcctggagct agtgatgaga ccaccacaga gtgtcaaagc
    84001 tgtatgatct aacagctact agaaagctct cgtgtcccct atcacatgca taggatcagt
    84061 gcgcacgacc tttcaagaca agcaagcatc agctcttgct tgtctttttt tggcctcaaa
    84121 gaccgttagt ctgctgctat gcgaggcttt ttttgagtat cagaacctca aaaaaaagga
    84181 catggagtcc tttttggggt gattggtgtt gaggccgtca caaactgccc ttgaaatacg
    84241 cttctatgtg gagctttttt tgatcctgtg acacgtaagc tccaacgacc tccagctgac
    84301 agcctcttgg aaacaagagc tcaacctctg aaggcacagc cgaataaggc tcgacaaagg
    84361 ctgctttggc cccttttttg acacagatgc gcacctccac cggtcgatgg gtcatggcgc
    84421 cgtttttcaa ggctgtcgtg ctcataaaac tgtgcttggt gtagcgtgta ccaagcttga
    84481 tcttacaaag gatatgaggg tcaaactgat ggttacggta gtaagacgtg agatcagcgt
    84541 gtgaaacacc gatatcacgc aaaaacgtct cgtacacata gcggtatact acaatgttcc
    84601 acgggatgac tagccggtga gtcgcagcat cgagctgggc cacctgatcc cttagctcag
    84661 gcgtgagttg gctgagctcc cctttggcct tgtctaggct ggtgttgata ggggctgcct
    84721 gctggcaggt ataagcagcc atcgcctctt gctcagccct tgggtagaca agacccttgc
    84781 cccagcgctt tttaatcagt gtctcagcga ccttttgatc cgaaaaggta aaataagcag
    84841 gcgtcccctc acaaaccgcc cgctcatagt gctcgcagac aaaaagctcg accaagcctt
    84901 cagtttgcca gatcagacta aaacagctaa gaagaaggac aatagccagt tgatagcgct
    84961 tttttagcat agttccccct gacaccagcc caaaaggcta ccccttcccc taggcctttt
    85021 ggctagctca tgataccacc agtttctcag acaggctaat ctttttgtca tctctttctc
    85081 cctaaacaga ctctcttatc atgatattat gctattatga gcgatttgtc aatccatagc
    85141 aaccgttttt tagccagata agtaagcttt tgacctagag gcagacaaga gtggcagtac
    85201 ctgccgtttg ctgtggtggc taataaggac taacataaaa tatcaaacgc tttcaaaaac
    85261 agctcctaag cttaaaaaag ctgatgaaca gatttgttga gcttaaggga aattgtcatg
    85321 tttttatcat ttgatgttta aaatgataaa aacatgaact tgaaatgaaa gaatgcgaat
    85381 agtaaactat aactatatca aaatgatgaa atggagtgat tttatgaaaa caaaatcaaa
    85441 acgcttttta aacctagcaa ccctttgctt ggccctacta ggaacaactt tgctaatggg
    85501 acgtcccgta aaggcggagg cggtgacaca gacaacagaa ggagtgcaac aaattgaaga
    85561 aaatgcagaa gatagagata ttaaagaaga atatatgaaa cgtatgggga taacagattc
    85621 agatttagaa gacgaagaac aggcgtatct taaaaagaga gttcaaggtt atttaaaagg
    85681 ttatgcagat ggtcaaaagc taaatgctcc agaacaacca agtgactata atccgagttc
    85741 tgatgatgat tataacgatg gttataccga tggctattct cgtagttggc ataaaactaa
    85801 tcagcctata cgaacagcac tgtacgatgc ttttgaatgg tttgtgggat ggttagaacg
    85861 tttttttgag ggtaggtaac tagttttact tatcaataaa gtcctagtgt tatttttggg
    85921 ggatgacatt ttatttttct actctgaaat aacgctgaga aaatagtttt taagtttata
    85981 atgatatttt tgtcgtatct acttaaaaat tttacaatca atcgctttga tacaagtaat
    86041 ttttatacta atctactata attgggatag tccctttagt agtcaggcca cctctgatag
    86101 gggtggcctc agattgaaga caaacatcga tttggtgttt gtctttttta gtgtttttag
    86161 ataaaaatgg ctgtttccgt gcttaaacca cctcatctga acaaaataaa aaggctctcc
    86221 cgccatcctt ttgacccgtt ttttgagatt taagcatgcc aaagtcagtc caaccttatc
    86281 ttccattttg gacttgcctt tctctctcgt atagcggaga ttgtggtatt ccttggctgt
    86341 gccaaacagt cgttcaatcg tctctttccg atgctggtag agctccttca tccccctttg
    86401 atgacgaatg tcctcgcact gttccaaata gtatttccaa atatgccgtg tgataacttt
    86461 ttggtggttc ttactggtcg tacatacaga tgacagggga caattagcac aaattgcagg
    86521 gtcacttttg tattctcggt agccttctct ggtcgtagtg cggtaggtca aggcttgatg
    86581 ttcaggacag atgacacaat caaagtgctc atcataaatc aattctttcg gacgtagaag
    86641 gtctttcttt cctcttggtc gtgtgtaagg aaggacagga gtgatctcct tatcaatcag
    86701 aaacttggca atgctgggaa tgttatagtc ggaatccgca ataataaact gtggtttcaa
    86761 gggttcaagc ttggcaaaaa gtgcaggaaa agcctgacta tcatggatat tgccagcctc
    86821 aacactataa gcaagcgccc atccatactt gtcacaagcc acctgagcag aataagcgaa
    86881 gacttcctta tgatttgtga aaccagccac tttctggatc ggttgtggag attttcttag
    86941 cgacgggctc tagctctttg gcgggcccta gcggcttttt tccatgcttc tccctgtccc
    87001 gattgatttc gatttctagc tgttcactca tgaacttggc ttgtttttcc acctctcggt
    87061 tgatgaactt gcgattatta gccgcagcct taatatgagt cccatctatg aaaatctccg
    87121 tcgggtcaat caggcctgta ttgatacata gcccaagaat atgcgtaaaa atggactcaa
    87181 tcaagccttt ttcttgaaag cgacgggaat aatttttgcc ataggttgtg aaatgtggca
    87241 ccttgtcatc caaagtcaaa cctaaaaacc agcgatagga agtattcact tcaatatcct
    87301 tgatggtctg acgcatggaa cgaatgccat aaaagcactg aatcagaggg attttaacca
    87361 acatgacagg atcaaggcta gggtgactat tatcagacga ataggtgtct tctactaggt
    87421 catagatgaa gtcgaagtca atcacagctt ccacttggcg caggaaatgt tcatcaggca
    87481 ctaactggtc aagggtatag aaaccgtact gattgcggtt ataatcaggt ttttctttgt
    87541 gtaacatagg agaacctcac aagtcctttt tcttatatta tactcctaaa tatcatgaaa
    87601 agcccctaga aaagcgattc taaggacttt gtcttcagtc tgaggccacc tctgataggg
    87661 gtggcctttt tgggttttag tgacccgtgt gttgagaaag gagcatttat gccagaaaag
    87721 aaagtgttgc ccgtccgttg cctaatatga accgacagtt attccttatt aaatagacgc
    87781 aaatatccac gctttcactg tggtggctaa taaggactaa cacaaaatct caaacgcttt
    87841 caaaaacagc ccctaagctt taaaaaggct gatgaacaga tttgttgagc ttaagagata
    87901 ttgccatgat tttctaatca tttgatgttt aaaatgataa aaacatgaac ttgaaatgaa
    87961 agaatgcgag tagtaaacta gaaccgtatc aaaaataatg aaatggagtg attttatgaa
    88021 aacaaagtca aaacgctttt taaacctagc aaccctttgc ttggccctac taggaacaac
    88081 tttgttaatg acacgtcccg taaaggcgga agtaactgta tctgaaggtg agagtgcttc
    88141 tcaccagaca acaaaatcaa cctctctagg caacttgttt ttaagtagcg aaggtggaga
    88201 aaatggtagg tatgattatg atttttggca cagactagga tacagtgaag gatatgaaaa
    88261 aggaaaagaa tcagatggcc caggtatcga taatatcgat gttcctgaga atgtattaga
    88321 caaaggagca tataaagatg gttatgaagg aggtcatgaa gcaggatggc gggatactca
    88381 tccaatcgaa tcacttctag atatggcatg gcaatttttg acatatgcat tcaataattt
    88441 atttggcttc ggtcagaaca ctcagtaatt gatctattcg ttttttaatt tagttattgt
    88501 gacttattga aaagcttgag gatactttcc ttagctcaag catttcccac acgaatctgc
    88561 tataattggg ataatccctt tagtagtcag gccacctctg ataggggtgg cttttttggg
    88621 ttttagtgac ctgtgtgttg agaaaggagc atttatgcca gaaaagaaag tgttgcccgt
    88681 cctaagcatg gtggtgagtt ttgtctgcct gcttgatcat atcttctttt ttgggctcct
    88741 tttcaactgt attgggtgac ttatagctaa acacgtgagg agacgagact cgtcttctct
    88801 tttgttatgt tcaaagcgag gtaaatgcgt tttttaaagt tatcaaagtt ccgaaaacca
    88861 aaagcattgc gtttgatgag tttattggtt gcttctagtt tggcgtttga acaaggaagc
    88921 tcaatggcat tagtgacaga gtttttgtat cgcatcaggg tgttcaaagc cgttttaaag
    88981 gtgtgattga gcagaagtaa cactttttga attaagtcaa aaaatgctca gtattcttct
    89041 cttgtaagtg aaaaaggagt aactgataaa ggtcatagta atcttttaat tcaggaacga
    89101 gattaaatag tttattgaga cattgtttag gagttagcgt ttccctaaaa gttctagagt
    89161 agaaggcgtt gagcgagagt tttcggctac cttttgaatg agttgacagt agtatttaag
    89221 aactctgtat tccagagact ttttgtcata ttgcttcatg atgtgaatcc gggtttgact
    89281 gagcgctctg ttcatgtgct gaacaatatg gaaacgatct aggacgatgt tagcttgagg
    89341 aaatagcttt ttaatgagcg aaatatagct tcctgacata tcaacggtaa cgattttgac
    89401 actgtttcta gccgctttag agtatctaaa gaagtgattt cgaatggttg tttgtcgccg
    89461 gttgtccagt atggagatga tttttttgga ctcaaaatct tgagcgataa aggcgagttc
    89521 gcccttttga taggaaaatc catcccaaga taacacctcg ggtagtttag agaagtcttc
    89581 cttgattaca aactggttga gttttcggta gacggtagaa gatgatatag ccgactgttg
    89641 agcgatgtta gtgagagcgc ctcgattaac caaggtttgt gcgacttttt gtctgagggg
    89701 ctcagagatc tgacagtttt tttgaaccag atttgtttcc gctacagcca cttttcgaca
    89761 ggacttgcat tgagatcttc tcttttttaa acgaatgaga ctagggaaac caccaatttc
    89821 gataaagggg attttagaat gtttctggga gtcgtattta atctgaactc ctttacagtg
    89881 tttacactta ggtgggagat agtcaagtgt ggcgaagact tcgataggtg tctcgcgttg
    89941 aaaaaccttg ttcaaggtga tgtgtttatc tttaattcca atcaattctg tagtatgata
    90001 gagttgtctc atatgattct ttctaatgat ggtttggtcg ctttgcatta taagtcatat
    90061 gggatttttt gctacttata gttatctcta cttgtcgttt gtagcaagta gtctagccat
    90121 tgtaggtctt gtataaaaca aaagcaagtg ttcgctggct gggcttgtag tagcagtaac
    90181 agtataatat gaaccgacag acattcccta ttaaaataga cgcaaatgtc cacgctttca
    90241 ctgtagttgc tagtaaggtc taacacaaaa catcaaaggc tttcaaaaac aactcctaag
    90301 cgcaaaaagg cggactaaca gccccaagta agcactttct gaggtaataa gagattgcca
    90361 tgattttcta accatttgat atttaaaatg aaaaaaacat gaacttgaaa tgaaagaatg
    90421 cgagtagtaa actgaaaata tatcaaaatg atgaaatgga gtgattttat gaaaacaaaa
    90481 tcaaaacgct ttttaaacct agcaaccctt tgcttggccc tactaggaac gactttgcta
    90541 atggaacagc ccgtaaaggc ggatggagct ggtaatagtg ataaggcaga atttcacgga
    90601 actccgtatg atttaggcgt tcgagatggt tatcgaaaag ggttagaaga tggtaaagtt
    90661 gccggcaagc agacgggaac tacgtcggaa ccacctaagg gatcagatag tccgaagact
    90721 agtccttata ctgaagagaa tcaaaaagct cgatatacga gagcctatca agagtggtat
    90781 ctccatggat atcgtgcagg ttggcatgag acacacaatc aaattagtga gagaggcgaa
    90841 gaagaaaata aaaccccaga agcttctcac gagaaggaag ggcgtcaaga agaaaataga
    90901 accccagaag cttctcacga gaaggaaggg cgtcaagaag aaaatagaac cccagaagct
    90961 tctcacgaga aggaagggcg tcaagaagaa tcaggtagtc aggaagaaga tatattgtca
    91021 cctattgttg aaacagttga aacaattatt gaagctgttt tagaagcttg gacttatgtc
    91081 ttcaattggt ttaactcata gtattcagaa attagctttt catataatgt ctgtagcctc
    91141 tgctataatt gggatagtcc ctttagtagt caggccacct ctgatagggg tggctttttt
    91201 ggggtttagt aacccgtgtg ttgagaaagg agcatgtatg ccagaaaaga aagtgttgcc
    91261 cctctgttgc ctaatatgaa tcgacagtta ttccttatta aatagacgca aatatccacg
    91321 ctttcactgt ggtggctaat aaggactaac acaaaatctc aaacgctttc aaaaacagcc
    91381 cctaagcttt aaaaaggctg atgaacagat ttgttgagct taagagatat tgccatgatt
    91441 ttctaatcat ttgatgttta aaatgataaa aacatgaact tgaaatgaaa gaatgcgagt
    91501 agtaaactag aaccgtatca aaaataatga aatggagtga ttttatgaaa acaaaatcaa
    91561 aacgcttttt aaacctagca accctttgct tggccctact aggaacaact ttgttaatga
    91621 cacgtcccgt aaaggcggag gtggtgacgc agacaccaga aggaaaagtt actaaagcag
    91681 agggtagagg taacgttgat gatgaggctc aaaaatacca gagaagatgg gaagcaggtc
    91741 ataaaaaggg atatgagaaa ggaaaagaac ctgattctcc aagagagcct caagaaatac
    91801 ctgaaggtac tggtgatgat tatggtgatg gctacagtga tggctatagt acaggttatg
    91861 gagaaggatg gtacgatagt catccaatca cagcactact agacatggct tggtactact
    91921 taacatatgc atttggtgct ttgtttggtg gtgcaaattc ttagtaaatg acgtatttgt
    91981 tgtcctaatt tagttattgt aacttattga agagcttgag gatactttgc ttagctcaag
    92041 ccattccccc actaatctgc tataattggg atagtccctt tagtagtcag gccacctctg
    92101 ataggggggc ctttttgggg tttagtgacc cgtgtgttga gaaaggagca tgtatgccag
    92161 aaaagaaagt gttgcccgtc ctaagcatgg tggtgagttt tgtctgtctg cttgatcata
    92221 tcttcttttt tgctacttat agttatctct acttgccgct tgtagcaagt agtctagctc
    92281 ttatcggcct agtgcaaaac aaaggcaggc aaaaggtttg gtcgctagct gggcttatct
    92341 tagctgctct agctgtggca gtagtggcct atgcctacta tgacccaacc gtcatcccct
    92401 attaacctta ccccctcttt gcacgcagtc aacatcacaa aaagcacccc tgacaggtgc
    92461 tttttgtact ttagccaacc tcatagcctc ataaaccctc actgaaacag tcccttaaag
    92521 ttccaccact gaccttggat gctttcgctt aaccgctgat gccaagattt atggtcttct
    92581 tctcttatct gctttagcat gctttcttct agttgttttc ttaattcatt atcgcgtttt
    92641 ttttcctctt cttgttcctg tgctttttcc gcttgcagcc ttgtgttttg tgttttttca
    92701 tcttcgaaga ctagtttacc aaatattaag ttgccatcgt ctgcgaagga gagagtcaca
    92761 atgtctcctt cttgtaattc tttagtgagt tgaacactcc aatacccact accatcagcg
    92821 cgattaccac taaccatcca ttttcgttct atacagccgt tactagttgt aggacacgta
    92881 accttaactt ccttagctcg aggatttatt ttatctacac tattatctct atgctttata
    92941 ctaccatata catattcata agaacctagc tgtacgctaa tagtcgaatc tccaacttta
    93001 aaagatttaa ctgtgatccc tggtatagtt tgttgtccgg ggacttgctt gaaggtgata
    93061 tcctccgctc tgacgctact agttaccccg atggcaaaga gtgccagtag caaggttaat
    93121 gtctttttca ttttttcctc tccttttgct cattttttaa gacaaggctt attataccaa
    93181 ttcttgcgct aaaaagatag ggcgtttatg tcttgtggtt gaaaaatggc gcgactattt
    93241 ttggtagggg cagacagttt ttttctagcc agttactagc cgttgccctt ttacctttgc
    93301 aagccgtttg ggcatcaggt cgtgttttga ggttgccaat acttttagtt gctttttgac
    93361 aaaaatgcgt tatgatagac taaataaaag aagatagcat tttcggtgaa tgatgcgtga
    93421 gtccacaaat ttatttttag gagtttatag actgcctaaa gtgtccattt cgtcaataaa
    93481 ggagaacaat atgacatttg aagaaattct accaggttta aaagccaaga aaaaatatgt
    93541 acgtacaggt tggggtggcg ctgaaaatta tgtgcagtta tttgataccc ttgaagtgga
    93601 tgggaaagta ctacaggcga caccttattt tctgattcat gttactggtg caggtgaagg
    93661 tttttccatg tgggcaccga caccatgtga tgtgttagca gaggattgga tcgaggtcaa
    93721 tgactaaagt tgttttagtg acgggctgtg ctagtgggat tggttatgca caggcccgct
    93781 attttttgag acaagggtat cacgtatatg gtgtggataa gtcggataaa ccggacttaa
    93841 acggtaattt tcactttatc aaattggatt tatcctctga gttatcccca ctatttaaag
    93901 tggtccccag tgttgatatt ttgtgtaata ctgcagggat tttagatgcc tacaagccac
    93961 ttttagacgt cagtgatgaa gaagtggaac acctatttga tattaatttt tttgcgacgg
    94021 tgaagttaac acgtcattat cttagacgta tggtggaaaa gcagtcaggt gttattatca
    94081 atatgtgctc aatagcaagt tttatagcgg gtggcggtgg tgttgcctat acgagttcta
    94141 agcatgcgct tgcgggcttc acgcgccaat tggctttgga ttacgccaaa gatcagattc
    94201 acatttttgg tatagcgcca ggtgctgtca aaactgctat gacggctagc gactttgagc
    94261 ctggtggctt agcagactgg gtagctcgtg agacgccaat tggtcgttgg actaaaccag
    94321 atgaagttgc tgaattaacg ggatttcttg cgtcaggaaa agcgagatca atgcaaggtg
    94381 aaattgtcaa aattgatggt ggctggactt tgaaatgatc acatgcctta gcttgagctg
    94441 gcgcagtaag ccctagaggt gtgacgagtc aaacagtcaa aggagatgaa caaatgaaat
    94501 tagcggtttt ggggacaggt atgattgtta aggaagtttt gcctgtcttg cagaaaattg
    94561 atggtattga tttagttgct atcttatcaa cagttagaag tttaaagaca gctaaagacc
    94621 tcgctaaggc atataagatg cctctagcta cgagtaaata tgaggctgtc ttaggcaatg
    94681 aggagattga cacagtttat attggactgc cgaatcacct gcattttgcc tatgctaagg
    94741 aggcccttct agctggtaaa catgtcattt gtgaaaagcc ctttaccatg acagcaggag
    94801 aattagatga actggtggta atcgctaaaa aacgaaaact cattttgtta gaagcgatta
    94861 cgaatcagta tttaagcaac atgaccttta tcaaagagca tcttgaccaa cttggcgata
    94921 tcaaaattgt agagtgtaat tattcacaat attcttcacg ctacgatgcc ttcaaacgag
    94981 gtgatatcgc gccagctttt aatcctaaaa tgggtggtgg agctttacgt gatttaaaca
    95041 tctacaacat tcattttgtg gtaggattat ttggtcgccc taaaacggtt cactatttag
    95101 ccaatgtcga aaaaggcatt gacacctcag gcatgcttgt catggactat gagcagttta
    95161 aagtggtgtg tattggggcc aaagactgca ctgcagaaat caaatccacc atccaaggta
    95221 ataaagggtc actggcagtg cttggagcaa caaataccct tcctcaggtt gagttaagtc
    95281 tacacggtca cgaagcacaa gtggttaatc acaacaagca tgaccaccgg atgtatgaag
    95341 agtttgtcgc ttttagggac atgattgacc aaagagactt tgagaaagtg aatcaggctt
    95401 tggaacatag ccgagctgtc atgtctgtgt tggagcgggc tgttcattcg tgatggtaat
    95461 ctggtagcca ttgccttttg tgcaggtgct atggtaatgg ttgaaagacg tgttttcacg
    95521 agggttaacc ccctcgtgct tttttggtaa aaataacttg ttcaggattt gggccttctt
    95581 tgtgagatga gagatgcctg acgaattgat ttgattaaaa taatgataaa gccaaacgat
    95641 ttaagaaatg accgttcgga aattctgccc caaaggggct ctagaagcag taaaatcgaa
    95701 tttgtaagcg ttgacactgt tgcataactc tgttacacta agagaatgtc atgacaaaaa
    95761 ttacagtgta ggagtttaat tgtttatgga agaggattat aacaaaagag aacctgagaa
    95821 gtttacgcaa tttctgcgcc gtcaaaaggt tgtctttttt gtcgcatttt ttggttatgt
    95881 gtgtgcttac ttggtacgca acaatttcaa actaatgtca aacactatta tggtacaaaa
    95941 tggttgggac aaggctcaaa ttgcgacctt gctatcgtgt ttgaccgttt cttatggttt
    96001 agcaaaattc tatatgggag ccttagggga tcgtgttagc ttgagaaagc tcttttcaat
    96061 cagcttgggt gcaagcgctt tgatttgtat tttaattggt tttttcaata gttcaatggt
    96121 ggtgttaggg atactgctag tcttgtgtgg tgtcgtacaa ggtgccttgg cacctgcctc
    96181 acaagccatg attgccaatt attttccaaa taaaacacgc ggcggagcca tcgctggatg
    96241 gaacatttct caaaacatgg gatcagccct cttgccatta accatcgcct tgctcaccag
    96301 tatgggcttg gtggtaccag ctaatggcaa tattttactt gcctttttaa ttcctggcgt
    96361 tttagtgttc ttgtttgctt tgtgttgctg gaagcttggc ggtgataacc ctgagtctga
    96421 gggacttgac tctcttcgaa cgatgtatgg tgatgcgggc gagtcagctg ttgccagtga
    96481 agaagaaaag cataacctgt cttattggca actcatctgg aaatacgttt tttgtaaccc
    96541 gtcgctctta cttgttgctg ctgtcaatgt ggccctttat ttcgttcgtt ttgggattga
    96601 agactggatg ccgatctact tgtcacaagt agccaatatg tcagaggctc atatccattt
    96661 tgcgatttca atgttagagt gggtcgctat tccaggctcg ctggtatttg cgtggttagc
    96721 ggttcgttat cctaataaaa tggccaagat tggggctatt gggctttttg tgttagcggc
    96781 tattgtcttt gtctatgaac gcttgactgc cacaggtgct ccaaactatt tcttgttgct
    96841 tgttattgca ggtattttag ggtcattgat ttatggccca cagttgatcg tgaatatttt
    96901 aacaatcaac tttgttcctt taaatgttgc aggaacagcg attggttttg taggagtaac
    96961 agcttatctc atcggcaata tgggagcaaa ctggctgatg ccgattttag cagatggttt
    97021 tggctggttt tggtcatata ttgtcgttgc agccttatct gctttttcag cggttggtta
    97081 tttgatttta gccaaacgtg aggaagaaat catcaaagat tagctaggca aatgcctaag
    97141 aaagacagac ttattgctga agtcctgtct tttttagtca tcacaagccg caaatgacac
    97201 tataaaagac aagaaaatgc taggatgttt caggaaaaaa agagaaaata tgctataatg
    97261 agaaggtatt taaattatat agtaaggaaa aacaaatgac aaattatgcc attattttag
    97321 cagcgggcaa agggactcgc atgacttctg atctcccaaa agttcttcat aaagtatctg
    97381 gactaaccat gcttgagcat gtttttcgta gtgtaaaagc gattagtcct gaaaaagccg
    97441 tgacggttat tggtcacaaa tcagaaaagg tacgtgctgt cttagcagat caatcagcct
    97501 ttgtccatca aacagagcag ttaggaactg gccatgccgt gatgatggca gaaacacaac
    97561 tagaaggact agaagggcat accttggtga ttgcaggaga tactcccttg atcactggag
    97621 aaagcctgaa gagtctgatt gattttcatg tgaatcataa aaatgtcgcc actattttaa
    97681 cagctacggc tcaagatcca tttggttatg gtcgtattgt tcgcaacaaa gatggcgaag
    97741 tgatcaagat tgttgagcaa aaagacgcca atgagtatga gcaacaatta aaagaaatca
    97801 atacaggaac ctatgtgttt gataacaagc gtctctttga agcgctcaaa tgcatcacta
    97861 ccaacaatgc tcaaggagag tattacctga ctgatgttgt ggctattttt agagcaaaca
    97921 aagaaaaggt aggagcctat atcctgagag acttcaatga aagtcttggt gttaatgatc
    97981 gtgtggcctt agcaacagct gaaacagtga tgcgtcagcg catcacccaa aaacatatgg
    98041 tcaatggggt gacctttcac aatcctgaaa ctgtttatat tgaaagcgat gttgagattg
    98101 caccggatgt tttaattgaa ggaaatgtga ccttaaaagg gcgtacacat atcggctcag
    98161 gaactgtctt gacgaatggt acttatattg tggattctga aattggtcaa ggaagtatca
    98221 tcaccaactc aatgatcgaa tcatctgttt tagctgcagg agttacggtt ggcccttacg
    98281 cccaccttcg accaggaacg accttagata gggaagtcca tatcggtaac tttgttgagg
    98341 tcaagggttc tcacattggt gaaaaaacaa aggctgggca tctgacttat attggaaacg
    98401 ctcaggttgg gtcttcggtc aatgttgggg ctggaaccat cactgtcaac tacgacggcc
    98461 aaaacaaata tgaaacagtc attggagatc acgcttttat tgggagcaac tcgactctca
    98521 ttgcaccttt ggaagttgga gataatgctt taacagcagc tggctcaacg atttctaaga
    98581 cagtaccagc tgatagcatt gttattggtc gtagccgcca agtcacaaaa gaaggttatg
    98641 ccaagcgcct agcgcatcac ccaagtcgaa gcaaataatt caagatctat ttagtaagga
    98701 ggccaggcat gaaatttgaa gaaaaaacgc ttaagagaca aacagttttt gatggtcata
    98761 tttttaaagt tgttgtggat gatgttgaac ttcccaacaa tctggggcaa tccaagcgag
    98821 aattaatttt tcatcgtggt gccgttgctg ttttggctat tactcctgaa cgtaagattg
    98881 tccttgtcaa acaataccgt aaggctattg aaagtgtctc atacgagatc ccagcgggta
    98941 agctagagat tggtgaggaa ggctcaaagc taaaagctgc tgcacgtgag ctagaagaag
    99001 aaacagccta tacggggaca ttgacgtttt tgcatgaatt ttatacagcg attggttttt
    99061 gcaacgaaaa aatcacactt ttcttagcga cagacctaac acaagttgcc aatcccaaac
    99121 ctcaagacga cgatgaagtt atcgaggtct tagagttgac atatcaagag tgcatggact
    99181 tagtcgctca aggtaaactt gctgacgcta aaacgttgat tgctttgcaa tactatgcct
    99241 tacattttgg aggtgagcag tgatgggaag gccattgttg accgatgata tcatcgaaaa
    99301 agcgagacga atggaaacat ttgagccaga tgatgctgta gactttgaca caaaagtaat
    99361 gacgctacca gaaaaagatg aaaaagcacg catttataaa agccgtcgga ttgaaaatgc
    99421 caaacgcagc caattgcaat ctaaattaaa tgtgattttg atagctgtta tgctgttaat
    99481 tgccatcttg gtatatgcta tcttttatct ttaaaaaaac gtaaggaaat gatatgaaaa
    99541 taggaattat tgctgctatg gaggaggagt tgtccctgct cttagcaaat cttttggatg
    99601 ctcaagaaca tcaggtgctt tcaaaaactt actatacggg tcgttttggc aagcatgagc
    99661 tcattttggt acagtcaggt gttggaaaag tgatgtctgc tatgacagtt gcgatcttgg
    99721 ttgagcattt caaagcccaa gctattatca atacaggatc agcaggggca gtcgcttcac
    99781 atttagcgat tggagatgtg gtggttgcag atcggttagt gtatcatgat gtggatgcta
    99841 ctgcatttgg ttatgcttat ggtcaaatgg ctggtcaacc attatactat gattgtgatc
    99901 cacagtttgt ggctatcttc aaacaggtcc taaaacacga aaagacaaat ggccaagttg
    99961 gtttgattgc aacaggagac agttttgttg ctggtcagga caagattgac cagatcaaaa
   100021 cagcttttag cgacgtgcta gcagtagaaa tggaaggcgc agctattgct caagcagcac
   100081 atactgcagg gaaacccttc atcgttgttc gtgcgatgag tgataccgca gcgcatgatg
   100141 ccaatattac ttttgatcaa tttattatag aagctggcaa gcgttcggcc cagacattaa
   100201 tgacattttt agaaaactta cctgtttaac tcaccttatc gtgagacaat tagctggata
   100261 atctctattt taggagtctg gtcacctctt gttttgaaac ctaaaaataa gaattgcaat
   100321 cacttgacca aacgctataa tgggttaagg aacgatagat tactaaaagg agtctaaaaa
   100381 tgatactaaa aaaacactat tatcttctca gtctgctagc tcttgtaacg gttggtgctg
   100441 cctttaacac aagccagagt gtcagtgcac aagtttatag caatggagga tatcgtcaag
   100501 atttgactaa tcaaaaatca aagctgcaat atagtaaaga caacgcaaaa cttcaattga
   100561 gaaatatcct taacggctac caagatgacc tagggaaaca ttactctagt tattattact
   100621 acaacctaag aatcgttatg ggactatcaa gtgagcaaaa gattgaaaaa tattatgaag
   100681 agcttaagaa caagttacat aatatgtaca agcattatta agtcaaaggc ttaaaaatgg
   100741 agactagccc ctcaaaaaaa gaggccacac tcatttaaat ttaaatgagt gtggcctctt
   100801 tttgaggaga cgcaaggggt taaagggctg tgacatagag ttgcttagca atattttcag
   100861 ggatgataag gtccttgtcg ccataacaaa tcgtataggt ttttgcaaag gtatcaattt
   100921 gagttaaggt tagctcggta ttgatattga ggtgatgtgc ttccagatac tggattaaat
   100981 caaagtggtc gtggattctg cttaggcgaa accgtcccaa ctccgtgatg gtgttgagag
   101041 ttgtagtgtt catttcgaca agaggctggc catagcgagg aatagtccct ccgtgtgggc
   101101 agaaatctgg aaaatcaagg atcttgtcta aacggtcgat aaaggtgtct gagacagtgt
   101161 gctctaagac ttcagcttct tggtgcactt cttgggtatt atagcccagc tggtgaatca
   101221 aaaatacctc aatcaagcgg tgtttgcggt agaggttagc aacaagagca tagcctttgt
   101281 cttttagcaa atagcctttt gctttatctt tgacaatcca gccttgtgaa atcatttttt
   101341 taatcatctc tgaaacggca ggtgccgaaa cgtgcatctt ttctgcaacc attttatttg
   101401 taatcttggg ttcttgttct ccaatttcat aaatacattt caagtaatct tctttattag
   101461 gcgtcatatc gtttggcctt tctcttattt ataatgatta ttatatcaga atttttagga
   101521 aaaagcttga caaaaagcct aaaagaggat atccttatag cataattaac taaacttaat
   101581 taaataaata atatatccta aggagagaaa tgatgggaaa gagaatgagc ctcattttgg
   101641 gtgctttttt atctgttttt cttttagtag cttgttcgtc aactggcact aaaactgcta
   101701 agagtgataa attaaaagtc gtggcaacca attcaattat tgccgacatg acaaaagcta
   101761 ttgctggtga taaaatcgat ctgcacagca ttgtgccaat cggtcaagat cctcatgagt
   101821 acgaaccatt accagaagat gttgaaaaaa caagtaatgc tgatgtgatt ttctataatg
   101881 gtatcaatct agaagatggt gggcaagctt ggttcaccaa actagtgaaa aatgctcaaa
   101941 aaacgaaaaa caaagattac tttgccgtgt ctgatggcat tgatgtgatt tacttggaag
   102001 gtgcaagcga aaaaggaaaa gaagatccac atgcttggtt aaatctcgaa aacggaatca
   102061 tttattcaaa aaacattgcc aaacaattga ttgcaaagga tcctaaaaac aaagaaactt
   102121 atgaaaagaa cctaaaagct tatgtggcta aattggaaaa actagacaaa gaagctaaat
   102181 caaaatttga tgctattgca gaaaataaaa aattgattgt gactagtgaa ggctgcttca
   102241 agtacttttc aaaagcttac ggtgtcccat ctgcttatat ctgggaaatt aacaccgaag
   102301 aagaaggaac accagatcaa atttcatcat tgattgaaaa actaaaagtc atcaagccat
   102361 ctgcgctttt tgtagagtcg agtgtcgata gacgccctat ggaaactgtt tctaaagata
   102421 gtggtattcc tatttattct gagatcttta cagattcaat tgctaaaaaa ggtaaacctg
   102481 gcgatagtta ttatgctatg atgaaatgga accttgacaa aatttctgaa ggtctagcaa
   102541 aataagataa caataaagca cagcgatttt agtgttgtgc tttgttttat ttatgtaaag
   102601 gagacaaaat gattacaact aacaatcttt gtgtgaccta cgatggcaac agtaatgctt
   102661 tagaagcgat taatgtgaca attgatggtt cttctatcgt tggtattatt ggtcctaatg
   102721 gagctggaaa atcaaccttt atgaaagcta tcttaaatct tattgattat caaggtcacg
   102781 taacggttga tggcaaagat ggtcgtaagc ttgggcatac agtagcttac gtagaacaac
   102841 gaagcatgat tgactataat tttcctatta ctgttaaaga atgtgtggcg ctagggactt
   102901 atagtaaatt aggccttttt cgccgagtag gaaaaaaaca atttgagcag gttgataagg
   102961 ttctcaaaca agttggttta gaagactttg gccatcgacc gataaaatcc ttatctggtg
   103021 gtcagtttca gcggatgttg gttgcgcgtt gcttgattca agaatcagac tatattttct
   103081 tagatgaacc gtttgttggc attgactcgg tcagcgaaaa aatcattgta gatcttttga
   103141 aagagctcaa aatggctggc aaaacgattt taattgtaca tcatgatttg agcaaagtag
   103201 agcattattt tgacaaactc atgattttaa ataaacattt ggtggcttat ggcaacgttt
   103261 gtgaggtatt tactgttgat accttgtcaa aagcttatgg caatcatttg attttaggaa
   103321 aggagatggt gtaaatgtct atgaaatttt ttgagggctt gatgtcatac cactttttac
   103381 aaaatgcact gataacggct gtagtcattg gtatcgtctc aggtgctgta gggtgtttta
   103441 ttatccttag gtcaatgtct cttatgggtg atgccatctc acacgctgtt ttaccagggg
   103501 ttgctttgtc atttatttta ggagtcaatt tttttattgg agcgattatt tttgggttat
   103561 tagcttctgt tattattact tatatcaagg aaaattctgt cattaaagga gatacggcta
   103621 ttggtatcac ctttagctct tttttggcac tgggagtcat cttgataggg gtagccaata
   103681 gttcgacgga cttatttcat attttgtttg ggaatatttt agctgtgcaa gatagcgata
   103741 agtggattac tattggtgtt tcgatttttg ttttagtggt tattagtctc tttttcaaag
   103801 aactattatt aacatcattt gatcctatct tagccaaatc aatgggtgtg aaggtcaatg
   103861 cgtatcatta tttgttgatg gtcctattaa ctttagtggc tgttacggcg atgcaaagcg
   103921 tgggtactat cttgattgtt gccttactga ttacgccagc agcgacagct tatttatatg
   103981 ctaatagctt aaaagtaatg ttagtgatgt catctttact aggcgcttta gcatcggttt
   104041 tagggcttta tctgggctat acctttaatg ttgccgcagg gtcaagtatc gtactgactt
   104101 ctgcgatgat gtttttgatc agtttctttg tttcacccaa gcaaggctac ctcaaaagat
   104161 ggatgcaaaa aaaagaaaaa acaccttaaa cttttcgctt taaacacctt agtggtttgc
   104221 aaatagtggc aaatgacatc aaagggtgtt ttttatatgt catcaaaaga ccataaaaaa
   104281 ccttatcaaa ccaaggtatt tagcctatta tctgataagg tttttttaag catgatttag
   104341 tttttaaagc gataatcttt gacaatgtca attgaggtaa tcgtaatgtc ttgttctggt
   104401 ttatcatttt ggttgataga agtcgcggca attttatcga caacatccat accatcaatg
   104461 acttgaccaa atacagtata accgccatct aagcttggat taccgccatg ctcataggca
   104521 gagatgatag gttttgggta gttagtactt gataatccct tgctttgatt tttcttgttt
   104581 tggttgatat aaaattggct accgttagta ttagcaccag catttgccat ggcaagagca
   104641 ccgcgaatat gatataaaaa tggagagatt tcgttgacaa agccattgcc agcatctttt
   104701 ttaggatcct tgcctttcca aatcgattca ccacctgtgc catctccttt ggggtcacct
   104761 gattgaatca taaagtcgtt gatcacacga tggaaggtaa ggttatcata gtagcctttt
   104821 ttagcatggg tgaggaagtt ctcaacagct aagggagcat attttgggaa taacttaagg
   104881 gtaatgtccc cttgacttgt cctcattacg accttagctt cttctttgcc gacttctttg
   104941 gttagttgtg gaaattggct agcatcagct ttgagagctt tttgaatgct ttcttcatag
   105001 gctttagaag ctgcttcgct ttcttctttg gcagtttttt catcaatgta tttatcgcct
   105061 tttatagcgc ggtcaacaga ttcacaagca ctcaaactaa gtaaactaat ggctactaaa
   105121 ctgagagata ataatttttt catgtctact cctaagaatg attttcttta ttttatcata
   105181 aaatgcaaca gaaaatagta gtaaagagtt aaaaacgcct atttttgtgt tttatgatct
   105241 aaccttggtt aaaaggctgc tacgactgtt attatagcac aagatgctat agaaaaactt
   105301 aaaacacctt ggttttttag agctatttcc taatagttaa aaaatggtat aatagtgtta
   105361 tggttaaaag aaatcaaaga aaaaaaagtg cgcctaagaa gcgtttaaca aaagcagaag
   105421 tggaaaagca acgtgccatt aagaggatga ttttatctgt tttaatggct ttgttgctta
   105481 tttttgcgat gcttcgcttg ggcgtctttg gcgtgacaac ttataatatg attcgttttt
   105541 tggtgggtag tttagcctat ccgtttatgt ttgcctggtt aatttactta ttttgtttta
   105601 aatggttacg gcaaaaagat ggaatgattg cgggagttgt tattgccttt ttgggattgc
   105661 tagttgagtg gcacgccttc ttatttgcga tgcctaggat gcttgatcaa gatatttttc
   105721 taggcactgc tcggctaatt acaagagatt tactagccct gcgcgtgact gaatttgttg
   105781 gtggaggaat gcttggtgca ttactttata aacccatagc ctttttattt tcgaatatcg
   105841 gctcttactt tattggtttt ttgtttatct tattaggatt atttctaatg acgccttggg
   105901 atatctatga tgtgagtcac tttgtgaaag aggctgttga taaactagca gtggcttatc
   105961 aggaaaataa agaaaagcgg ttcatcaaac gagaagagca ccgcttacaa gctgaaaaag
   106021 aggctttaga gaagcaagca caagaggaag aaaaacgtct agcagaattg acggttgatc
   106081 ctgagacggg agagattgtt gaggatagtc agtctcaagt cagctatgat ttggctgagg
   106141 atatgacaaa agagccagag attcttgctt atgatagtca cctcaaagac gatgaggcaa
   106201 gcttatttga ccaagaagac ttggcttatg ctcatgagga aattggggct tatgactctt
   106261 tatctgcttt agcatcttct gaagatgaga tggatatgga tgaacctgtt gaagttgatt
   106321 tcacaccaaa aacccatctt ctttataaac ttccaacgat tgatttattt gcaccagata
   106381 agcccaaaaa ccagtccaaa gagaaaaact tagtccgcaa aaatatcaag gtgcttgaag
   106441 ataccttcca aagttttggg attgatgtca aggtagaacg agctgaaatt ggaccatcag
   106501 ttactaaata tgaaattaaa ccagctgtcg gggtccgagt taatcgtatt tcaaatcttg
   106561 ctgatgattt ggcacttgct ctggctgcta aagatgttcg tattgaagca ccaattcctg
   106621 gaaaatcctt aataggtatt gaagttccta actcagaaat tgcaacggtt tctttccgcg
   106681 aactttggga acaatctgat gccaatcctg aaaatctttt agaagtacca ctaggtaaag
   106741 ctgttaatgg caacgctcgc agttttaact tagctagaat gccgcatctt ttggtagctg
   106801 gttcaactgg ttcaggtaaa tctgtggcag ttaatggcat tatttcaagt attttaatga
   106861 aggcacgtcc agatcaagtt aagtttatga tgattgaccc caaaatggtt gaattatctg
   106921 tttataatga tattccacat ttattaatcc cagttgtaac caatccgcgt aaagccagta
   106981 aggcactcca aaaagtggtt gatgagatgg aaaaccgcta cgagttattt agtaaaattg
   107041 gtgtgcgtaa tatagcaggt tataatacaa aggttgaaga gtttaatgct tcttctgagc
   107101 aaaaacaaat accgttgcct ttaatcgttg tcattgtaga tgaattggct gacttgatga
   107161 tggtggctag taaagaagtt gaagatgcta ttattcgttt ggggcaaaaa gcgcgtgcgg
   107221 caggtatcca tatgattctt gcaactcaac gtccctctgt agatgttatt tctggtttga
   107281 ttaaagcaaa tgttccgtcg cgtatggcat ttgctgtttc aagtggtact gatagccgta
   107341 caatccttga tgaaaatggt gctgaaaagc tcttgggacg gggtgatatg ctctttaaac
   107401 cgattgatga aaatcaccct gttcgcttgc aagggtcttt catctcagat gatgatgtgg
   107461 agcgtattgt caactttatc aaagaccaag ctgaagcgga ttatgatgac gcctttgatc
   107521 ctggtgaagt tagcgacaat gatcctggtt tttctggaaa tggcggagct gctgaaggtg
   107581 atcctctttt tgaagaagca aaagccttgg tcttagaaac acaaaaagct agtgcctcaa
   107641 tgattcaaag gcgtttgtcg gttggattta atcgtgccac gcgcttgatg gatgaattgg
   107701 aagaagcagg tgttatcggt ccagcagaag gaaccaaacc tcgtaaggta ttgcagacaa
   107761 actaaaagaa cctgacgtct catgatgaga tgttagattc tttttttgtg atgtcaggcc
   107821 agttgatgag atgcctatgc taatgtaaaa ataaagataa ctagaataag gtagaaaata
   107881 acggtgacta aaaaaccaac tcgccaaaat agcttcataa agcgatggta agaaaacgac
   107941 tgagttcgga tgactagcag tagtgaaatg acgatggcta gcagcgacat gataataaga
   108001 taataaggca gtaaattatg ggtgaaaaat tttcctgaga caagcacaat ttctatcgca
   108061 aaaagtaaaa gtgcgacatc tggaaattta aatccctttt tattaagttt aaataaagag
   108121 gttacaatca tggcaaaaag aggcgttact atcaagaaag ctaaggcagt taatttatag
   108181 atcatcatag gtctatttta tactcaaatc ccttacttgt aaactgatac ttacctgttg
   108241 tgatagaaaa tgatctttga gagggaaagc gcctacttca atttaaacat tacaaaaggc
   108301 atcagctatt ttaacaaaaa gacttgattt attttggcaa taagctataa tggtaaggta
   108361 tgcaatattg catatctgtg ggaggtaaaa atctcaatta ccgccaaaac cacaacagga
   108421 ggatttttaa aatggctaaa aaagtcgaaa aacttgtaaa acttcaaatc cctgctggta
   108481 aagctacacc agctccacca gttggaccag ctcttggtca agcaggtatc aacatcatgg
   108541 gcttcactaa agaatttaac gctcgtacag ctgatcaagc tggtatgatc atcccagttg
   108601 ttatctcagt ttatgaagac aaatcatttg atttcatcac taaaacacca ccagctgctg
   108661 ttcttttgaa aaaagctgca ggtgttgaaa aaggatcagg tacacctaac actactaagg
   108721 ttgcgacagt tactcgtgca caagtacaag aaattgctga aactaagatg ccagatttga
   108781 acgctgcaaa cattgaagct gcaatgcgta tgatcgaagg tactgctcgt tctatgggat
   108841 tcactgttac tgactagtca gtcaagaacc cctattaccc gcacgacttc atcataagag
   108901 atgagtgacg tgggagattt taaatcaaat cgatatgacc acattacaag gagaatttta
   108961 aaatggctaa aaaaagcaaa caaatgcgtg ctgcacttga aaaagtagat agcacaaaag
   109021 cgtacagtgt agaagaagct gtagcattag taaaagaaac gaacttcgca aaatttgatg
   109081 cgtctgttga agttgcttac aacttgaaca ttgacgttcg taaagcagac caacaaatcc
   109141 gtggcgcaat ggtattgcca aacggaactg gtaaaacaca acgtgttctt gtttttgcac
   109201 gtggtgcaaa agctgaagaa gcaaaagcag ctggtgcaga cttcgtaggt gaagacgacc
   109261 ttgttgcaaa aatcaatggt ggatggcttg actttgacgt tgttatcgca acgccagaca
   109321 tgatggctat cgtaggtcgc cttggacgtg tccttggacc tcgtaacttg atgccaaacc
   109381 ctaaaactgg tacagtaacg atggatgttg ctaaagccgt tgaagagtct aaaggtggta
   109441 aaatcactta ccgtgctgac aaagcaggta atgttcaagc tcttattggt aaagtttcat
   109501 ttgatgctga caaattggtt gaaaacttca aagccttcca cgatgtaatg gctaaagcta
   109561 aacctgcaac agctaaagga acttacatgg caaacgtctc aatcacatca acacaaggtg
   109621 ttggtatcaa ggttgatcct aactcacttt aagaaaaaat tagggcatcg cctaatcata
   109681 gcaaaaagac aaatttctga agacaaatct tcactagagg tttgtctttt ttatggttta
   109741 aaatggaatg caaacaaaaa agtgtaggcg ataataccat gaaaggagtt gattctctta
   109801 atgagatgtg gtgttaacac atcatgagct cacaaaaaat gataaagaaa gtatcggtgg
   109861 tgttaaaaaa gggattttaa ttgatattta ttagcctcta aaatgtcctt tccctattca
   109921 taattgaggg tttgtggtaa aatagtaagg acaaactaag gagaacatag tagtggaacc
   109981 taaatatcaa cgtatattaa ttaagttatc tggtgaagca ttagcaggtg aaaaaggagt
   110041 tggcattgac attccaactg ttcaggctat tgcaaaagaa attgccgaag ttcatgtgtc
   110101 gggagtacag atcgctcttg ttattggtgg aggcaatctc tggcgtggag agcctgcagc
   110161 agacgctgga atggaccgtg ttcaggctga ttacactggc atgcttggaa cggtgatgaa
   110221 tgccctagtc atggctgata gtcttcaaca ttatggtgtt gatacccgtg tgcaaacagc
   110281 tattcctatg caaaatgtag cagaacctta tattcgcgga cgtgccttgc gccatctaga
   110341 aaaaaatcgg attgttgttt ttggagctgg tattggctcg ccttattttt caacagacac
   110401 caccgcggca ctgcgtgctg ctgagattga agcagatgct attttaatgg caaaaaatgg
   110461 tgtggatggg gtctataatg ctgatcctaa aaaagatgct aatgcggtta aatttgatga
   110521 attaacacat ggtgaagtga tcaaacgtgg tctcaaaatc atggatgcaa cggcatcgac
   110581 cttatcgatg gataacgata ttgatttggt ggttttcaat atgaatgaag ctggcaatat
   110641 tcaacgtgtt gtctttggag aacatattgg aactactgta tcaaataaag tttgtgacta
   110701 aaagttagaa aagaaagaga gtaattatca tggcaaatgc aattattgaa actgcaaaag
   110761 aacgttttgc acaatcccat cagtctttat cacgtgaata tgccagcatt cgtgcgggtc
   110821 gtgccaacgc tagtctttta gaccgtatcc aagttgatta ttacggggca ccgacgccat
   110881 taaatcaatt ggcttcaatc actgtgccag aagcgcgtgt cttattgatc tcgccttttg
   110941 ataaatcttc tatcaaagat atcgagcgcg ctcttaacgc atcagattta ggcattacac
   111001 ctgctaacga tggctctgtc attcgtttgg ttattccagc tttgaccgaa gaaacacgta
   111061 aagaattagc caaagaagtg aaaaaagttg gtgaaaatgc taaaattgca atccgtaata
   111121 tccgccgtga tgctatggat gatgctaaaa agcaagaaaa agcaaaagaa atcactgaag
   111181 atgagttaaa aacacttgag aaagatatcc aaaaagcaac cgatgatgct atcaaagaaa
   111241 ttgaccgcat gacggctgaa aaagaaaaag aattgctctc agtgtaacag gatttctacg
   111301 aaaaatagac gactatagac acaaaaagat aggtgaccat ttcagaagcg tttggttttg
   111361 atttgtccct atttttttaa agaaagaaaa aagatatgaa tgatttacta gcaacagtca
   111421 ttactgggct tattaaagaa gaaaacgcta atgactattt tatccaaaaa gaagggttta
   111481 cctttacctt gtctaaagca gaaggagaac gccagattgg tgatatggtc acaggctttg
   111541 cctatataga cataaagcaa aaggcacgtc tcacaaccaa agagatccgt tcaacacgga
   111601 caagttatgg ctggggggaa gtgacagagg ttcgtcgtga cctaggcgtt tttgtcgata
   111661 caggaattcc aaataaagaa attgtggttt ctttggacgt gttgcctgag atgaaagaat
   111721 tgtggcctaa aaaaggggat aaactttaca ttcatttgga tgtggacaaa aaagaccgta
   111781 tttggggact tccagcagag tctgaggtct ttcaaaagat ggctagccct gcatacaata
   111841 acatgcaaaa tcaacattgg ccagcaattg tttaccgcct aaaactaaca ggaacgtttg
   111901 tttacctgcc tgaaaacaac atgttgggct ttattcaccc aagtgaacgc tacgcagaac
   111961 cgcgcttagg tcaggtttta gatgcccgtg tgattggctt tagagaggtc gatcgtaccc
   112021 taaacttgtc gttgaaacca cgttcttttg agatgttgga gaatgacgct cagatgattg
   112081 ttacttatct ggaagccaat ggtggtttca tgaccttaaa tgacaagtca agtccagaag
   112141 agattaaggc aacctttggt atttcaaaag gccagtttaa aaaagccttg ggtggattga
   112201 tgaaagctaa acgcatcaaa caagacgcca caggaactga attaatagga taaaaatgct
   112261 ttgccactgg caaagttttt tgttacaatg aagaccatta actgaagaaa aaggggatat
   112321 agagaatgga aagagccatt tttgcaggag gttgtttttg gtgtatggtg caaccttttg
   112381 aggagcaagc aggtattttg tcagtcagaa gtggctacac aggtgggcat ctcccaaatc
   112441 ctagctatga acaagtttgt gccaaaacaa caggacatac agaagctgtt gaaattattt
   112501 ttgaccctaa gcaaatcgct tataaagatt tggtagagct ctattgggcg cagacggatc
   112561 caacagacgc ctttgggcaa tttgaagatc gtggggacaa ctaccgtcct gtcatttact
   112621 acacaacgga aagacaaaaa gaaattgcag agcaatcaaa agcaaacttg caagcttcag
   112681 gacgttttga ccaacccatt gtcaccacta ttgaaccagc agagccattt tatctcgcag
   112741 aggattatca ccaaggattt tataaaaaga atcccaagcg gtatgcacaa agcagtgcta
   112801 ttcgtcatca gtttttagag gagaattggt catgagaaaa tcattttaca gctggctgat
   112861 gacacaacgt aaccctaaat caaatgaacc tgtggcgatt ttagcagatt tggtgtttga
   112921 tgacaccact tttccaaagc ataccaatga ttttgaactc attagtcggt atctagaaga
   112981 tcaagctagt ttttccttta atttaggtca atttgatgaa atctgggaag attatctagc
   113041 acattaatac gtggataaaa aagagtcata tcgactcttt tgaagggtta tcacgttatt
   113101 attacaaaat gacatcactt tctttcaaaa aaatgacaag ctactttttt tcttaaaaat
   113161 atgctatgat atagcttaga aaaaaataaa aaggaagcag agatgattat tactaaaaag
   113221 agcttatttg tgacaagtgt cgctttgtcg ttagcacctt tggcgacagc gcaggcacaa
   113281 gagtggacac cacgatcggt tacagaaatc aagtctgaac tcgtcctagt tgataatgtt
   113341 tttacttata ctgtaaaata cggtgacact ttaagcacaa ttgctgaagc aatggggatt
   113401 gatgtgcatg tcttaggaga tattaatcat attgctaata ttgacttaat ttttccagac
   113461 acgatcctaa cagcaaacta caatcaacac ggtcaggcaa cgactttgac ggttcaagca
   113521 cctgcttcta gtccagctag cgttagtcat gtacctagca gtgagccatt accccaagca
   113581 tctgccacct ctcaaccgac tgttcctatg gcaccatctg cgacaccatc tgatgtccca
   113641 acgacaccat tcgcatctgc aaagccagat agttctgtga cagcgtcatc tgagctcaca
   113701 tcgtcaacga atgatgtttc gactgagtcg tctagcgaat cacaaaagca gccagaagta
   113761 ccacaagaag cagttccaac tcctaaagca gctgaaacga ctgaagtcga acctaagaca
   113821 gacatctcag aagacccaac ttcagctaat aggcctgtac ctaacgagag tgcttcagaa
   113881 gaagtttctt ctgcggcccc agcacaagcc ccagcagaaa aagaagaaac ctctgcgcca
   113941 gcagcacaaa aagctgtagc tgacaccaca agtgttgcaa cctcaaacgg cctttcttac
   114001 gctccaaacc atgcctacaa tccaatgaat gcagggcttc aaccacaaac agcagccttc
   114061 aaagaagaag tggcttctgc ctttggtatt acgtcattta gtggttaccg tccaggtgat
   114121 ccaggagatc atggtaaagg tttggccatt gattttatgg tgcctgaaaa ttctgctctt
   114181 ggtgatcaag ttgctcaata tgccattgac catatggcag agcgtggtat ttcatacgtt
   114241 atttggaaac agcgattcta tgcgccattt gcaagtattt acggaccagc ctacacatgg
   114301 aaccccatgc cagatcgcgg cagtattaca gaaaaccatt atgatcatgt tcatgtctcc
   114361 tttaatgctt aattcatgct atcaaaaaaa actcacgttt aggcgtgagt tttttgacaa
   114421 ttctgacaga gtaagcccta taagaggctg agatacgctt ttaatacctg ttgtttttct
   114481 caccctttgg acagttttaa cgttatgtct aaaagagatg gtttttatta gcgcaaatat
   114541 gggtttaggg gtaaaataaa ggtaattaac ctgatatgat catgataaag gtagaaggat
   114601 acctattatt tcgtgacaac tgagcaatct gccttacctt tggagtgatg atatcacttt
   114661 gcttgactat tcaaggaggt cttgaaatgt attatactag tggtaattac gaagcttttg
   114721 caacacctcg aaaacctgaa ggggtagatc agaaatcagc ttatattgtt ggtactggtt
   114781 tagctggttt agcagcagct gttttcctta ttcgcgatgg gcatatggct ggggaacgca
   114841 ttcatctgtt tgaggaattg cctttagcag gtggttcttt agatggtatt gaaaagcctc
   114901 atcttggttt tgtgacccgt ggtggtcgtg agatggaaaa tcattttgag tgtatgtggg
   114961 acatgtatcg gtctattccc tcactggaaa ttcccggtgc gtcttattta gatgaatttt
   115021 attggttgga taaggatgat cctaactcat ccaactgtcg tttgattcac aagagaggaa
   115081 atcgtgtgga tgatgacggc cagtatacgc tcggtaaaca gtcaaaagaa ttaatccatt
   115141 taatcatgaa gacagaagaa tctctaggag accaaaccat tgaagagttc ttctcagaag
   115201 atttctttaa gagtaatttt tgggtgtatt gggcaaccat gtttgctttt gaaaaatggc
   115261 attctgctgt agaaatgcga cgctatgcga tgaggtttat ccaccatatt gatggtttgc
   115321 cagatttcac ctccctcaag ttcaacaaat ataaccaata tgactctatg gtcaaaccga
   115381 ttattgctta cctagaatca cacgacgttg acatccaatt tgacacaaaa gtcactgata
   115441 ttcaggtgga gcaaacagct ggtaaaaagg tagcaaaaac catccatatg acggtgtctg
   115501 gggaggctaa ggcgattgag ctaacacctg atgatttggt ttttgtgacc aatggttcta
   115561 ttactgaaag cagcacatac ggtagtcatc acgaagtggc taagccaacc aaagcgttag
   115621 gtggttcttg gaatttatgg gaaaatctag ctgctcaatc agatgatttt ggtcatccta
   115681 aagtgtttta ccaggacttg cctgctgaaa gctggtttgt gtctgccaca gcaaccataa
   115741 aacacccagc tatcgagcct tatattgaac gtttgaccca ccgtgacttg cacgatggca
   115801 aagtgaacac tggcggcatc atcactatta cagattctaa ctggatgatg agctttgcca
   115861 ttcaccgtca acctcatttt aaagaacaaa aagaaaatga gaccactgtc tggatttacg
   115921 gtctttattc caatagtgag ggcaattacg tccacaagaa aattgaggag tgtacaggtc
   115981 aagaaatcac agaagaatgg ttgtaccacc ttggggtacc tgttgataaa atcaaggact
   116041 tagcgagtca ggaatatatc aatacagttc ctgtttacat gccttatatt acgagttact
   116101 ttatgccacg cgtcaaagga gaccgtccga aagttatccc agatggttca gtcaacttgg
   116161 cctttattgg taactttgcg gaatctccat ctcgagatac ggtctttacg actgagtatt
   116221 ctattcgtac tgccatggaa gcagtgtata gcttcttgaa tgtggaacga ggcatcccag
   116281 aagtctttaa ttcagcctat gatattcgtg aattgctcaa agccttttat taccttaatg
   116341 ataaaaaggc aatcaaggat atggatttgc caattcctgc actgattgag aaaatcggac
   116401 ataaaaaaat caaggatacc tttatcgaag aattgctcaa agatgttaat cttatgtaac
   116461 atgccttaga gtagttaaag ctgataagtt taggcttatc agcttttttg atgatttata
   116521 gaaaagtgat aaaggaaaag tctgacgtga acgtcacata agaatttaaa atttgttata
   116581 atgtaagcaa taaagatgaa agaaagaggg actctatttg caagagtatt ctattgacat
   116641 taccttaacc catcctgatg atgttttagc tctttttggt agcaacgagc gtcatttgaa
   116701 gctaatagaa gctcatttag gagttattgt tcacgcaaga accgagcgag tccaagtgat
   116761 tggtgatgat gaagaagctg tggaattggc tcgattgacc atcaaagccc tactggttct
   116821 agtgggtcgt ggcatggtgg tcaacacatc agatgtggtg acagctttat ctatggcaga
   116881 atctcatcag attgaccaat ttatggcgct ttatgaagaa gaaatcatta aagataacta
   116941 tggtaaggca atacgagtca aaacattagg tcaaaaaacc tatgttgata gtgtcaaacg
   117001 tcatgatgtg gtttttggtg taggacctgc agggacaggg aaaaccttct tagctgttac
   117061 gcttgcagtc actgctctga aaagaggaca ggtaaagcgt attattttga cgcgtcctgc
   117121 ggtagaagct ggtgaaagcc taggtttttt accaggcgat ttgaaagaaa aggtggatcc
   117181 ttacctcaga ccggtttacg atgcccttta tcacatttta ggcaaggaac aaaccacacg
   117241 cctgatggaa cgagatgtga ttgagattgc tccgttagct tatatgcggg gtcgtactct
   117301 ggatgacgct tttgttatct tagatgaggc tcaaaacacg accatcatgc aaatgaagat
   117361 gtttttgacc cgtcttggtt ttaattctaa aatgattgtc aatggagata cgagtcagat
   117421 tgatctccct cgaaatgtca agtctggttt gattgatgct actcagaaat tacaaggcat
   117481 taaacagatt gattttgtct atttctctgc taaagatgtt gtccgacatc ctgttgtggc
   117541 tgatattatc aaggcttatg aaatgtcctc agaggagatg aaggacttac taaaacctaa
   117601 ggctagtgac gttgaagctg actaccagcc aggcttgaca aaataccctg tgatcggtca
   117661 agagcactaa gacctttacg atgatgttta atatggcctt tttaaggagg attctatgga
   117721 tgatttaacc aaagctatta tggcagatga ggctaatctc tcctataccg aaagaggtat
   117781 ttttccttta tatgatgctc ctcaaacagc taggattatt attgttggcc aagctcctgg
   117841 aatagtagct caagaaacca aactttactg gaatgatcgt agtggcatcc gcttacgaga
   117901 ctggctaggt gtggacaatg acacctttta ccactcagga ttgtttggca ttatccctat
   117961 ggatttctat tatcctggta agggaaaatc cggtgactta ccacctagag aaggttttgc
   118021 ggctaagtgg cacccgccat taagagcatt gatgccagaa gttgaattga cgattttggt
   118081 tggtcgctat gctcaggact tttaccttgg taacaaggct tacaaaacct taactgaaac
   118141 agtccgtcac tttgaggatt acttgccaga ctattttcca cttgttcatc cttctccaag
   118201 aaaccaattg tggttagcta agaacccctg gtttgagcag gatttattac ctatcttgca
   118261 aaaacgtgtg gaggcaattc taaccaaata ggccctgatt tatctagcat tcccattttt
   118321 aaggggcttg tggtataatg ggtaaataac aaatgctgat tgaaaggata agggaaatta
   118381 tctgtcagat aataatgggt gcccaacata ccaaatgagg tgggcagcct ttccctaaca
   118441 attaacctta tgtatatcga gatgattgac gaaacgggac aagtttcgca agagattatg
   118501 gagcaaacac ttgatttgct caattttgct gctcaaaaga cgggcaaaga agaaaaagaa
   118561 atgtctgtga cctttgtgac caatgaaaga agtcatgaac tcaacttaga ataccgagat
   118621 actgatcgtc caacagatgt gatttctcta gaatataagc cagaaacgcc tattttattt
   118681 agtcaagagg atttggctgc tgatcctagt ttggcagaga tgatggcaga gtttgatgct
   118741 tatattggcg aattgtttat ttctattgac aaggcgcgtg agcagtccca agaatatggg
   118801 cactcttttg agcgtgaaat gggattttta gctgttcatg gattcttaca tattaatggg
   118861 tatgatcact acacccttga agaagaaaaa gagatgttta ccttacagga agagattttg
   118921 actgcttatg gccttacacg acaataatac caccaaacgg aaatggaaaa acagaaccat
   118981 tacctcaagc ttggagtttg ccttgacagg ggttttcaca gcttttaagg aagaacgcaa
   119041 tctcagaagt caccttttgt ctgcctgttt agcttgtgtt gctggtttat tttttagcat
   119101 ttcagccatc gaatggttat ttttacttct agccattttt ttggtcatta ccttagaaat
   119161 tgtcaattct gctattgaaa atgtagttga tttggctagt gactatcact tttctatgct
   119221 agctaaaaat gctaaggata tggcagcagg tgctgttttg ataatttctg gctatgctgt
   119281 cttgacagga cttattattt ttattcctaa aatttggaat attttcgttc attaaaaaga
   119341 aaggaatggg ctatcctatg tgatgatggc ataggagaat aaggaaagga caagacggtt
   119401 aagcttagtg acaagcttga tctgaagccc taccgttaag gctcgtaatt atctatgttt
   119461 aaatcaggct ttgtagccat tcttggtcgt ccaaatgttg gcaaatccac ctttttaaat
   119521 cacgtcatgg ggcaaaaaat tgccatcatg agtgacaagg ctcagaccac ccgtaataaa
   119581 attatgggca tttacaccac agaaacagaa caaattgtct ttattgatac gccaggtatt
   119641 cataaaccaa agaccgccct tggtgatttt atggttgaat ctgcttatag tactttacgt
   119701 gaagttgaga cggttctttt catggttcct gccgatgaaa agcgtggtaa gggtgacgac
   119761 atgattatcg agcggctaaa agcagctaag attcctgtta ttttagttat caacaaaatt
   119821 gataaggttc atccagacca acttttggaa cagattgatg acttccgtag ccaaatggat
   119881 tttaaagaag tggtcccaat ttctgcccta gaaggtaata atgtgccaac cctaatcaag
   119941 ttattaactg ataatcttga agaaggtttc caatattttc cagaagatca gattactgat
   120001 catccagaac gtttccttgt gtcagaaatg gttcgtgaga aggtactgca tttaacgcaa
   120061 caagaggttc cacattccgt agctgttgtt gtcgaatcca tgaagcgaga tgaagagact
   120121 gataaagtgc atatccgtgc aaccattatg gtggagcgcg atagccaaaa aggcatcatc
   120181 attggaaaac aaggagccat gctcaaaaaa atcggaaaaa tggcgcgccg tgatattgaa
   120241 ctcatgttag gtgacaaggt ctacttagaa acgtgggtca aagtcaagaa aaactggcgg
   120301 gataaaaagc ttgatttagc tgattttggc tataatgaga aagaatacta acatagtaaa
   120361 gcgagatcat atgccacaag actacatttc ttatatccgc tccaaagttg ggcatgataa
   120421 gattattctt aactttgctg gtgggatttt gaccaatgat gacggcaagg tgctgatgca
   120481 gttgcgtggt gataagaaaa cctgggctat tcctggtggc actatggaac tgggtgagag
   120541 ctctttagag acttgcaaac gtgagttctt agaggaaacc ggaattgagg ttgaagctgt
   120601 tcgcttactg aatgtttaca ctcattttga ggaagtttat cccaacggtg atgctgttca
   120661 gactattgtc tttatctatg aactaacggc tgtttctgat atggctattg ataactttca
   120721 taatgaggaa acgctcaagt tacagttttt ctctcatgag gagatagcag agttagagag
   120781 tgtctcagcc aaacatcgcc tgatgttaga ggaatatttt agtgatagct ttgctatggg
   120841 gcattaagaa ctctctagga cagttggagt atttttggag attggcttgt taaaaaaatt
   120901 tttgaaagac gatgtttcga gagcttatgc tctctttttt tgcttccaat ttttctgatt
   120961 aagtctgaat aattttgtta aatgttaaca ggattttctt tccaattgat actagcagac
   121021 atcaaacatt tgttttagag ttatgacgaa ttgccaccta gccatgcatg acttaggcaa
   121081 gttgaaccta actgtggcaa tagacttgga aggggtgaca agaatcattt cctaaaagaa
   121141 ttgatgaagt gcctatccat tattcgaatt gtaaagttcg tctaagtaaa gttgaatttg
   121201 gtctcgaatg gatcttaatg atttatgact tgttgtgtca ataacaccaa aaactcgata
   121261 atgattttta aatatttcct cgtaattaat atgatttccg attagaataa tatgagcatg
   121321 aggataacgc atacgtattt cgtttagaag gtcatatact tgctcagatt taaaaaagta
   121381 tgatttat
//
LOCUS       DAUGSW010000002       100514 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUGSW010000002 DAUGSW010000000
VERSION     DAUGSW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 100514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100514
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.002"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(443..1570)
                     /locus_tag="VIB18_000124"
                     /pseudo
     CDS             complement(443..1570)
                     /locus_tag="VIB18_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1873..2670
                     /locus_tag="VIB18_000125"
     CDS             1873..2670
                     /locus_tag="VIB18_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8765167.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYHGEILFADMMTKEQYTEVAKKILANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            2674..3498
                     /locus_tag="VIB18_000126"
     CDS             2674..3498
                     /locus_tag="VIB18_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8765168.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            3498..5048
                     /gene="ftsY"
                     /locus_tag="VIB18_000127"
     CDS             3498..5048
                     /gene="ftsY"
                     /locus_tag="VIB18_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEQ8765169.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEAVQQEDVSSEGAGSVENGPEAASVNALVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEALDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKVAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNETINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKVIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(5102..6469)
                     /locus_tag="VIB18_000128"
     CDS             complement(5102..6469)
                     /locus_tag="VIB18_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8765170.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVREKAPFDWLAFIALSISLTSALLA
                     ITSLEDGSVNLYYLGLFILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            6797..7639
                     /locus_tag="VIB18_000129"
     CDS             6797..7639
                     /locus_tag="VIB18_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEQ8765171.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLIVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            7641..9503
                     /locus_tag="VIB18_000130"
     CDS             7641..9503
                     /locus_tag="VIB18_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8765172.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GEVYAPFDGEVITFFPTKHAVALKNARGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDTDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            9522..10946
                     /locus_tag="VIB18_000131"
     CDS             9522..10946
                     /locus_tag="VIB18_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8765173.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(11045..11860)
                     /locus_tag="VIB18_000132"
     CDS             complement(11045..11860)
                     /locus_tag="VIB18_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEQ8765174.1"
                     /translation="MIRFLILSGYFELTMYLQLSGKLDQYINVRYSYLAYISMVLSFI
                     LALVQLYTWMKNIKVHSHLTGKIAKLTSPFILVFPVLVGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(11860..12762)
                     /locus_tag="VIB18_000133"
     CDS             complement(11860..12762)
                     /locus_tag="VIB18_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEQ8765175.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            complement(12910..13065)
                     /locus_tag="VIB18_000134"
     CDS             complement(12910..13065)
                     /locus_tag="VIB18_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765176.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            13299..15431
                     /locus_tag="VIB18_000135"
     CDS             13299..15431
                     /locus_tag="VIB18_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEQ8765177.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            15418..15855
                     /locus_tag="VIB18_000136"
     CDS             15418..15855
                     /locus_tag="VIB18_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEQ8765178.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            15919..16191
                     /locus_tag="VIB18_000137"
     CDS             15919..16191
                     /locus_tag="VIB18_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEQ8765179.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            16556..17488
                     /locus_tag="VIB18_000138"
     CDS             16556..17488
                     /locus_tag="VIB18_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEQ8765180.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            17485..18264
                     /locus_tag="VIB18_000139"
     CDS             17485..18264
                     /locus_tag="VIB18_000139"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEQ8765181.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            18286..18693
                     /locus_tag="VIB18_000140"
     CDS             18286..18693
                     /locus_tag="VIB18_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEQ8765182.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            18686..19114
                     /locus_tag="VIB18_000141"
     CDS             18686..19114
                     /locus_tag="VIB18_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ8765183.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVRDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     FAEVEAKEKQDDVIIDLNEDDIIIDYTEQDEPVSDTLDKH"
     gene            complement(19274..19558)
                     /locus_tag="VIB18_000142"
     CDS             complement(19274..19558)
                     /locus_tag="VIB18_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEQ8765184.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM"
     gene            19757..20683
                     /locus_tag="VIB18_000143"
     CDS             19757..20683
                     /locus_tag="VIB18_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8765185.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            20785..22071
                     /locus_tag="VIB18_000144"
     CDS             20785..22071
                     /locus_tag="VIB18_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8765186.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSYRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPIEVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            22282..22494
                     /locus_tag="VIB18_000145"
     CDS             22282..22494
                     /locus_tag="VIB18_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEQ8765187.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(22591..22731)
                     /locus_tag="VIB18_000146"
     CDS             complement(22591..22731)
                     /locus_tag="VIB18_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765188.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(22867..24360)
                     /gene="lysS"
                     /locus_tag="VIB18_000147"
     CDS             complement(22867..24360)
                     /gene="lysS"
                     /locus_tag="VIB18_000147"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEQ8765189.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKDDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLFQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            24534..25436
                     /locus_tag="VIB18_000148"
     CDS             24534..25436
                     /locus_tag="VIB18_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8765190.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRSRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDINDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            complement(25544..26167)
                     /locus_tag="VIB18_000149"
     CDS             complement(25544..26167)
                     /locus_tag="VIB18_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8765191.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(26508..26987)
                     /locus_tag="VIB18_000150"
     CDS             complement(26508..26987)
                     /locus_tag="VIB18_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEQ8765192.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            complement(27079..27642)
                     /gene="thiT"
                     /locus_tag="VIB18_000151"
     CDS             complement(27079..27642)
                     /gene="thiT"
                     /locus_tag="VIB18_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEQ8765193.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMTLSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     regulatory      complement(27687..27783)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(27911..28759)
                     /locus_tag="VIB18_000152"
     CDS             complement(27911..28759)
                     /locus_tag="VIB18_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEQ8765194.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKISTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     gene            29084..29587
                     /locus_tag="VIB18_000153"
     CDS             29084..29587
                     /locus_tag="VIB18_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8765195.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGYQ
                     AFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            29571..29954
                     /locus_tag="VIB18_000154"
     CDS             29571..29954
                     /locus_tag="VIB18_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEQ8765196.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEVLKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     TADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(30000..30479)
                     /locus_tag="VIB18_000155"
     CDS             complement(30000..30479)
                     /locus_tag="VIB18_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEQ8765197.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     TDPLFAWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(30472..32271)
                     /gene="pepF"
                     /locus_tag="VIB18_000156"
     CDS             complement(30472..32271)
                     /gene="pepF"
                     /locus_tag="VIB18_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8765198.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRASDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIRDKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNELNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVMSTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSNTVDQIISYTEEMSHA"
     gene            32430..35228
                     /gene="ppc"
                     /locus_tag="VIB18_000157"
     CDS             32430..35228
                     /gene="ppc"
                     /locus_tag="VIB18_000157"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEQ8765199.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQTIIAEEVALLKEMLENITRR
                     MIGDDAFTVIKSIMVLSEKQDYIELEKVIANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINHQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLNTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNIIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            35368..36672
                     /locus_tag="VIB18_000158"
     CDS             35368..36672
                     /locus_tag="VIB18_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEQ8765200.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            complement(36689..36853)
                     /locus_tag="VIB18_000159"
     CDS             complement(36689..36853)
                     /locus_tag="VIB18_000159"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765201.1"
                     /translation="MVLIAATSFGIPRLIFATAKAAVWAHITRKNKKSAEQFKFFEHQ
                     TGIVYILKSP"
     gene            37025..38221
                     /gene="tuf"
                     /locus_tag="VIB18_000160"
     CDS             37025..38221
                     /gene="tuf"
                     /locus_tag="VIB18_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEQ8765202.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            38463..39221
                     /locus_tag="VIB18_000161"
     CDS             38463..39221
                     /locus_tag="VIB18_000161"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEQ8765203.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(39321..40556)
                     /locus_tag="VIB18_000162"
     CDS             complement(39321..40556)
                     /locus_tag="VIB18_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8765204.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(40543..41769)
                     /locus_tag="VIB18_000163"
     CDS             complement(40543..41769)
                     /locus_tag="VIB18_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEQ8765205.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTVGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(41769..42578)
                     /gene="yidA"
                     /locus_tag="VIB18_000164"
     CDS             complement(41769..42578)
                     /gene="yidA"
                     /locus_tag="VIB18_000164"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEQ8765206.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLRLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(42729..42977)
                     /locus_tag="VIB18_000165"
     CDS             complement(42729..42977)
                     /locus_tag="VIB18_000165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765207.1"
                     /translation="MAGLPLEFYALFLSLGSQKPRVTSLPVSTPLLPQQKAAVLAHVT
                     RRNKKSVVKSAEQFMLFEHQTGFVSSLRLKKEYFLQSF"
     gene            complement(43033..44334)
                     /locus_tag="VIB18_000166"
     CDS             complement(43033..44334)
                     /locus_tag="VIB18_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8765208.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSRGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            44416..44802
                     /locus_tag="VIB18_000167"
     CDS             44416..44802
                     /locus_tag="VIB18_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEQ8765209.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            45033..47714
                     /locus_tag="VIB18_000168"
     CDS             45033..47714
                     /locus_tag="VIB18_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEQ8765210.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(47798..48793)
                     /locus_tag="VIB18_000169"
     CDS             complement(47798..48793)
                     /locus_tag="VIB18_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8765211.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRISESI
                     KATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(48857..50764)
                     /locus_tag="VIB18_000170"
     CDS             complement(48857..50764)
                     /locus_tag="VIB18_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEQ8765212.1"
                     /translation="MFFAFARFKETVNPDFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFDALTKQEERLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDVTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSLCLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGIFLIIDTIQAQGNHCLVSQFILDNHLDVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKCNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNSHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(50850..51671)
                     /locus_tag="VIB18_000171"
     CDS             complement(50850..51671)
                     /locus_tag="VIB18_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8765213.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA"
     gene            complement(51658..52440)
                     /locus_tag="VIB18_000172"
     CDS             complement(51658..52440)
                     /locus_tag="VIB18_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8765214.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVVIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWSFAILGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCGA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(52459..52947)
                     /locus_tag="VIB18_000173"
     CDS             complement(52459..52947)
                     /locus_tag="VIB18_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8765215.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHQVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(52983..54182)
                     /locus_tag="VIB18_000174"
     CDS             complement(52983..54182)
                     /locus_tag="VIB18_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEQ8765216.1"
                     /translation="MTRSLKTIALEPIKQPERFTKKDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYTIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTSEAREAALKAADKLVQRYQDKGGFIQ
                     AWGELGKKQDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGEPVKGVTRQGYSDDSAWARGQSWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDSDPDKKTYE
                     AAMHSMLRALIKDYANKDLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(54182..54619)
                     /locus_tag="VIB18_000175"
     CDS             complement(54182..54619)
                     /locus_tag="VIB18_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8765217.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGQQEKVTAIDFTAEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLSNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            54955..55749
                     /locus_tag="VIB18_000176"
     CDS             54955..55749
                     /locus_tag="VIB18_000176"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEQ8765218.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLTAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            55774..56415
                     /locus_tag="VIB18_000177"
     CDS             55774..56415
                     /locus_tag="VIB18_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ8765219.1"
                     /translation="MKIALINENSQAAKNGIIYDALTTVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVTYLKSVLEQ"
     gene            56444..57445
                     /locus_tag="VIB18_000178"
     CDS             56444..57445
                     /locus_tag="VIB18_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ8765220.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADATMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQCNLDFAVATASLKCTVAEDQLYHSVQQVEAVLHNQRDVQR"
     gene            57450..58085
                     /locus_tag="VIB18_000179"
     CDS             57450..58085
                     /locus_tag="VIB18_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ8765221.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            58382..59032
                     /locus_tag="VIB18_000180"
     CDS             58382..59032
                     /locus_tag="VIB18_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEQ8765222.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            59728..60852
                     /gene="queG"
                     /locus_tag="VIB18_000181"
     CDS             59728..60852
                     /gene="queG"
                     /locus_tag="VIB18_000181"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEQ8765223.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRIYPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GKFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF"
     gene            60921..62019
                     /gene="prfB"
                     /locus_tag="VIB18_000182"
     CDS             join(60921..60992,60994..62019)
                     /gene="prfB"
                     /locus_tag="VIB18_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEQ8765224.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            62038..62730
                     /gene="ftsE"
                     /locus_tag="VIB18_000183"
     CDS             62038..62730
                     /gene="ftsE"
                     /locus_tag="VIB18_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEQ8765225.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            62723..63652
                     /locus_tag="VIB18_000184"
     CDS             62723..63652
                     /locus_tag="VIB18_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765226.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(63962..64660)
                     /locus_tag="VIB18_000185"
     CDS             complement(63962..64660)
                     /locus_tag="VIB18_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8765227.1"
                     /translation="MPFIFRYSFFNKVLIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            64828..65592
                     /locus_tag="VIB18_000186"
     CDS             64828..65592
                     /locus_tag="VIB18_000186"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEQ8765228.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDAVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLAGDDSNYITGQTIVVDGGMVFH"
     gene            65700..68201
                     /locus_tag="VIB18_000187"
     CDS             65700..68201
                     /locus_tag="VIB18_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEQ8765229.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLGHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFY
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFAR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            68536..69729
                     /locus_tag="VIB18_000188"
     CDS             68536..69729
                     /locus_tag="VIB18_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8765230.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKVAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            69750..71096
                     /gene="asnS"
                     /locus_tag="VIB18_000189"
     CDS             69750..71096
                     /gene="asnS"
                     /locus_tag="VIB18_000189"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEQ8765231.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVTKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            71511..72401
                     /gene="rapZ"
                     /locus_tag="VIB18_000190"
     CDS             71511..72401
                     /gene="rapZ"
                     /locus_tag="VIB18_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEQ8765232.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            72398..73375
                     /locus_tag="VIB18_000191"
     CDS             72398..73375
                     /locus_tag="VIB18_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEQ8765233.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNENDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            73372..74283
                     /gene="whiA"
                     /locus_tag="VIB18_000192"
     CDS             73372..74283
                     /gene="whiA"
                     /locus_tag="VIB18_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ8765234.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            74416..75813
                     /locus_tag="VIB18_000193"
     CDS             74416..75813
                     /locus_tag="VIB18_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8765235.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDEHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYSHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDTVYDPYGSEGTPVSKKIFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            75965..77512
                     /locus_tag="VIB18_000194"
     CDS             75965..77512
                     /locus_tag="VIB18_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEQ8765236.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGIVGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEEADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAESFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            77663..78385
                     /locus_tag="VIB18_000195"
     CDS             77663..78385
                     /locus_tag="VIB18_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8765237.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMIENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKVGKTPKTEILS
                     FEQYQVTPYLSGLLEFDPDTEVFELERLRIADDMPLMFERSYIPAQLFQGLSIEHLKR
                     KPMYDLFAEDYQETIRLAEEEFYASIALDYEAGLLGIKKGDPVLHIIRKTYNDNNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            78404..79603
                     /locus_tag="VIB18_000196"
     CDS             78404..79603
                     /locus_tag="VIB18_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEQ8765238.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCNSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQRYLFESVASTDLVAAP
                     DYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(79671..79931)
                     /locus_tag="VIB18_000197"
     CDS             complement(79671..79931)
                     /locus_tag="VIB18_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEQ8765239.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(80046..80987)
                     /locus_tag="VIB18_000198"
     CDS             complement(80046..80987)
                     /locus_tag="VIB18_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEQ8765240.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWMSQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            81381..81830
                     /locus_tag="VIB18_000199"
     CDS             81381..81830
                     /locus_tag="VIB18_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEQ8765241.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            82040..82324
                     /locus_tag="VIB18_000200"
     CDS             82040..82324
                     /locus_tag="VIB18_000200"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEQ8765242.1"
                     /translation="MRLEEIRQEINSIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QVRENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRKYQTQRLTGGDTND"
     gene            82317..83579
                     /locus_tag="VIB18_000201"
     CDS             82317..83579
                     /locus_tag="VIB18_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEQ8765243.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHV
                     GRYSGLGTHLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGVEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            83694..84041
                     /gene="rplS"
                     /locus_tag="VIB18_000202"
     CDS             83694..84041
                     /gene="rplS"
                     /locus_tag="VIB18_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEQ8765244.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            84288..84359
                     /locus_tag="VIB18_000203"
     tRNA            84288..84359
                     /locus_tag="VIB18_000203"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:84321..84323,aa:Arg,seq:cct)
     gene            85068..85637
                     /locus_tag="VIB18_000204"
     CDS             85068..85637
                     /locus_tag="VIB18_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEQ8765245.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVATFAPNELEFLHVYRLKEADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDIDSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            85638..87590
                     /gene="gyrB"
                     /locus_tag="VIB18_000205"
     CDS             85638..87590
                     /gene="gyrB"
                     /locus_tag="VIB18_000205"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEQ8765246.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            87958..89682
                     /gene="ezrA"
                     /locus_tag="VIB18_000206"
     CDS             87958..89682
                     /gene="ezrA"
                     /locus_tag="VIB18_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEQ8765247.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(89813..90271)
                     /locus_tag="VIB18_000207"
     CDS             complement(89813..90271)
                     /locus_tag="VIB18_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEQ8765248.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
     gene            90498..91805
                     /gene="eno"
                     /locus_tag="VIB18_000208"
     CDS             90498..91805
                     /gene="eno"
                     /locus_tag="VIB18_000208"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEQ8765249.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(92287..93316)
                     /locus_tag="VIB18_000209"
                     /pseudo
     CDS             complement(92287..93316)
                     /locus_tag="VIB18_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(93583..95124)
                     /locus_tag="VIB18_000210"
     CDS             complement(93583..95124)
                     /locus_tag="VIB18_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8765250.1"
                     /translation="MLHLHLETKLQDKLSLLNILLDVSEVSIDQLCQETELKKQRVYN
                     LLIEMIKDLEDTLTLTICDDTVSIPYKTYQLKMPYFKKLYQTSIFLKMLCFLIEPGEL
                     SLHDFIKREYISQATAYRIRTNCRKYLKKVGLNVRQNHVVGPEYRIRFLIALLHYQFG
                     MTIYDFDKTSMNKVVSLIINSNQAITLNDASKAPYEFSYFAILISLIWKRRHDNLGIP
                     QTDAFKHLKKLSIYRDIKMTSQEIIGKWYHPDLTDEDLDYIFLCFCTTNNSFHKDKWT
                     PKKVKELFELVMTKTNGKTLKASLRPLLGNNILNSLPFKRILVSFSRLFISNLQVLLP
                     DIHLFHYLRRQQKRNKSFYNTLKTIVEEWMSAEGIVGKLPSYHLLLFTIQLEELLKTY
                     LPPIPVYLLTNNTAALDLMTNALSIYFPPAIATVMPVNVEIIPFKDIVKEKQSVIIAD
                     RQYLNLIQHLYQNQGHLFLYFLFSFRDVSEAYIHKAFLDFRQKRYDEFIVTLLDTYHK
                     NLSSP"
     gene            96481..>100514
                     /locus_tag="VIB18_000211"
     CDS             96481..>100514
                     /locus_tag="VIB18_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ8765251.1"
                     /translation="MLQTVTVTKDQQNPISITLSEDQAKSLKNKEKLKVSIKQKQSKK
                     TSKDFFFEVGIDPKVEAKQKEKLLELDKVKKQIEDSINGDAWLPEKPEGEKPVQNTNK
                     ELQLQELNKKYQMAKEAIESATTLDDVETQFDKYTKVGDKDKYPDSLRNQYTQGDKDK
                     EIEKAKKSLGDLSDKVNGKIEEDKWLSAEVKKKQQQELEARKQKVNDSLKGSDSLKSL
                     RETVEKASSKNQKKPESFEDVYVPGNEETEKTKVRDILQKTYQKTEQNIETDPWLSPE
                     QKKAQKENAKTRLDAGLKAVETTESLDKLKEVESDFLDKEKAKSIPSQHQAGTPEVAR
                     KTFLDNFEKEAKKEIESIKNDVTLTDAEKATAKAKVEAQLQEAKGKAKESKSFDDLKN
                     IQDKFNSELPHTTGKPLKDQQSDAIAELEKKQQEIEKAISEDKTLSKDEKEKQIADSK
                     AKLVAEKEKVSKAPDADAVKKALESGKQEIAKAYVPQNLEDHKKKLLAELKQKANDTE
                     KAIDSDKTLTAKEKEEQKAKTKEELQKATEAVGAIDNREELDKKAPELKKAIQDSHVK
                     GDLEGVKNKAIEDLQKVHDETVAKINGDDTLDKATKEAQVKEADRALAAGKDAITKAD
                     DADKVGAAVTEHTPKIKAAHKTGDLKKVQEEANQALDKAAEKERGEINKDATLTTEDK
                     AKQLKEVETALTKAKDNVKAAKTADAINDARDKGVATIDAIHKAGQDLGARKSGQVAK
                     LEEAAKATKDKISADPTLTSKEKEEQSKAVDAELKKAIEAVNAADTADKVDDALGKGV
                     TDIKNQHKTGDPVEARREAHSKELDRVAQETKGTIEKDPTLTTEEKAKQVKDVDAAKE
                     RGMAKLTEAKDADALDKAYGDGVTDIKNQHKSGDPVEARRGLHNKSIDEVAQATKDAI
                     TADTTLTEAEKETQRGNVDKEATKAKEELAKAKDADALDKAYGDGVTSIKNQHKSGKG
                     LDVRKDEHKKALEAVAKRVTAEIEADPTLTPEVREQQKAEVQKELELATDKIAEAKDA
                     DEADKAYGDGVTAIENAHVIGKGIEARKDLAKKDLAEAVAKTKALIIEDKTLTDDQRK
                     EQLSGVDTEYAKGIENIDAAKDAAGVDKAYSDGVRDILAQYKEGQNLDDRRNAAKEFL
                     LKEADKVTKLINDDPTLTHDQKVDQINKVEQAKLDAIKSVDDAQTADAINDALGKGIE
                     NINNQYQHGDGVDVRKATAKGDLEKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNT
                     AIAAVDKATTADGVNQELGKGITAINKAYRPGEGVKARKEAAKADLEKEAAKVKALIA
                     KDPTLTQADKDKQTAAVDAAKNTA"
BASE COUNT        31217 a        17797 c        21302 g        30198 t
ORIGIN      
        1 tggaagtatg gaatacagat tttcatctgt agctttaaaa aataaaatta aaagcatact
       61 tgatagttga tgtatactgt catttagaat aataatcaca tattgttgtc aacgaaaccc
      121 accatagtct ataatgaaag cctagtaggg atgagctata taccaactat ctatcaatcc
      181 agacgtctct actaaaaaat actccgtctt ctatgaaact agaaacggag tatttctgtt
      241 tgtctatacc actaaatgaa cagttatata gaaaggtgat tggatgtttg gaataaacat
      301 catgaaaaaa atttgagacc ttcttatatc ctaaactaga acgaatgtct agtgaaataa
      361 aaaaaacgac accattagga tgtacatttt ggactaatgt caaataagta gacagaaaac
      421 cgtgttattt tattacgtta aactaatttt cttctttctg attaggggtt agtcctagat
      481 tagccgtatg tgggttgtaa ttgttataaa aattctcaat gtattcaaag cagtctaatt
      541 gaacctgttt gatattttga tacttttttc ggttgatttg tctatgcttt aaatacttga
      601 aaaatgcttc cgttacggca ttatcataag gatatccagg tttagaaaaa gaatgcatga
      661 tagtgttgtc atcaattatt tttctcaatt ccctggcctt aaattgtgac ccttggtcgg
      721 aatgaaagag aagtgtttct tcaatctttc ctttattaag agctaactct agagtgtcac
      781 atgctaactt tgcatccata cggtgactca atttccaagc aatacatttt ctagaataga
      841 gatcaagtat tgcgcagaga tagacatatt tcttatatcc aatagaaata taggtgaagt
      901 cagtagacca tacttgatta ggtttgtcag gattaaattt ctggttgagt aagttttgag
      961 gatacgtttt ttgagtcctt ttaagagctg tttttggctt aacggtagcc attttaggga
     1021 gcgccatatt cttcataaga cggtaaattc ttccttcaga gatttttgtg tcgtagtctc
     1081 tttgaagaat gactttgata gacttcacac caagtctttt gtttgctttg gtataaatct
     1141 caagtatttg ttttctataa atttgcttat ccaattctct tttggagggc ttatgtttta
     1201 gaaatttata gtaagtggag cgattgacac gtaaaacacg atacaatgtt gttgtggcgt
     1261 gttcaaagcg taactgatag acagcgagga gtcttacttt aagttttgca tgaatatggc
     1321 acttgctttt tttaggataa ggttctcctc ttcaagctgc gcattacgtt tttgtagctc
     1381 ttgtatttgc ttggcagtaa gtacagaatt atcttcgagt ttgacttgag aatactgttt
     1441 gatccatttt gcaagcgcag aagcggatac cccatagtct ttacagagtt cagactgagt
     1501 ttttccagtt tgataaaggt tgacaagaga ttgtttgaat tcttcattca tagcgtttaa
     1561 ctgttgacat aggttgtcct ttcgtttttg tgtcttttaa aacagattgt aacacacaaa
     1621 gttttgtcta cttttatagt atacatccag tggtcattta taaaaataaa aaagtagcag
     1681 ttcacttcaa aaacggtcag gttatcgaaa tataatctgg ctgtttttta cgaatggaat
     1741 gaaagctgct ttttatgata taataagaaa aattgaacag aatgcagaaa tgatggggct
     1801 tatttaaatc gttaaaaagt gcacacccta aatggcgttt gcacccccct agagtaaaaa
     1861 aggagacatt gtatgataaa actaatagca acagatatgg atggtacctt cctagctgaa
     1921 gatggtactt ataatcaaga gcaactagct gcgctcttgc caaagttagc cgaaaaaggt
     1981 attttatttg cggtttcgag tggccgctcg ctcttagcca ttgatcagct ctttgagccc
     2041 tttttggatc agattgctgt tattgcagaa aatggttccg tggttcaata ccatggtgag
     2101 attctatttg cagatatgat gaccaaagag cagtataccg aagttgcaaa aaagatttta
     2161 gccaatcctc actatgtaga aacaggtatg gttttttctg ggcaaaaggc agcctatatt
     2221 ttaaaaggcg catcagaaga gtacattcaa aaaacaaaac attactatgc taatgttaag
     2281 gttattaatg gttttgaaga tatggagaat gacgccattt ttaaagtttc taccaacttc
     2341 acaggccata ccgtcttaga aggaagcgat tggttgaatc aagccctccc ttatgccact
     2401 gcagtgacca ccggctttga ttccattgat attatcttaa aagaggtgaa taagggcttt
     2461 ggtatggagc atctttgtca agccttgggc attaagaaag cagaaacgat tgcttttggg
     2521 gataatttta atgattacca gatgttggag tttgctggta gggctattgc tacggaaaat
     2581 gcaagacctg aaatcaaagt gatttcagac caagtcattg gccactgtaa tgacggagca
     2641 gtactaacgt atttaaaagg actagtgtaa ctcatgaata ttagaatttt ggcgcttgat
     2701 ttagacggta ccctctacaa cactgaaaaa attgtcacag atgccaataa aaaagcctta
     2761 gcagcggcta gagaaaaagg ggttaaggtg gttattacca caggtcgccc tctaaaggcc
     2821 atcggtaact tgctagaaga gttggacttg cttgaccacg atgactacag tattaccttt
     2881 aatgggggtt tggttcagcg aaatacaggg gaggttttgg ataagagttc tctcagtttt
     2941 gaccaggtct gccagattca gcaagcttta gaggcggttg gcttaccaac agatattatc
     3001 agtggtgggg atgtgtatag cattccaagt aaggacggta ggcattcgca gtaccatcta
     3061 gctaacccac tgttgacctt tattgaggtg acatctgtag cggaactacc aaaagacatt
     3121 acctataaca aaattgtgac agtcaccgat ccagactttt tggatcagca gattataaag
     3181 ctatccccaa gcttatttga ggattttgaa gcctttaaat cacgagatat tatttttgaa
     3241 atcatgccaa aaggcattga taaagctttt ggattaaact tgctttgcca gcaccttggc
     3301 cttgacgcta gacatgtcat ggctatggga gacgaagcta acgactttgc gatgttagaa
     3361 tgggcaggac ttggagtagc tatggctaat ggtgtttcag gagctaaagc cgttgccgat
     3421 gccgtgacca ccttgaccaa tgatgagtct ggagttgcag aagctgtgaa gacatttatt
     3481 ttagaagagg agagttaatg ggattatttg atcgtttatt tgggaaaaaa gaaaccccga
     3541 aggtagctga ggaaaagtta gaagaaaatc ttttgacaga aacaactcag aaagaggagc
     3601 tttctgaaaa agccaatgag caagacaaga ttgaggcggt tcaacaagag gacgtttctt
     3661 cagagggcgc aggttcggtg gaaaatggtc ccgaagcagc ttcagtaaac gcactggttg
     3721 aggaagaaac aggtgacaat agtaatcatc catcagaaga taccaatgag tttgctgccg
     3781 acaaaacaga ccttaaggta agtgaactta gtcaatctac ggcatcagaa ccaaaagacc
     3841 ttgttgacca gccagttgtg gaacagtttc caacaaaaca agcccaagct gatgcctcaa
     3901 atgattcggc gaatgaagaa gcattagaca cttcaaaaga gcaatccagt agccaacagg
     3961 ttatggaaga ctactaccgt cgtaaggctg ctcttgaaaa aagccttcaa gaaaaagtag
     4021 cggcaacggt tccagtgatg ccagaagaag ttccacaaga aaatcaggcc tctacctcag
     4081 cagaagcttc tcaaaacaag gcaacccacg ataccattcc tgagacagat caagaaaaat
     4141 acaagcgtag cttgaaaaaa acgcggactg gcttctcagc tcgtctgaac agtttctttg
     4201 ccaatttcag gcgagtggat gaagaattct ttgaagactt ggaagaaatg ctgatcttat
     4261 cagatgtcgg tgtacatgtg gcgacaactt tgacagagga gttgcgttat gaagccaaac
     4321 tggaaaatgc gaaaaaacca gatgccttga aacgtgtgat tgtggaaaaa ttggtagata
     4381 tctatgaaaa agatgggcgt tataatgaaa ccattaatta tcaagatggc ttgacggtta
     4441 tgctttttgt aggtgttaac ggggttggta aaacgacttc aatcgggaag ctggcttacc
     4501 gttacaaaca agaaggtaaa aaagtcatgt tggtggcagc agataccttc cgagcagggg
     4561 ctgtggctca gctagtcgaa tggggacgcc gagtagatgt gccagtcatt actggccctg
     4621 aaaaggctga tccagcgtcg gttgtttttg atgggatgga aaaagctgtg gcaaaaggag
     4681 tagatattct tctgattgac acggctggtc gcctgcaaaa caaagaaaat ctcatggcag
     4741 agctggaaaa aatgggtcgt atcattaagc gcgtgctacc agatgcccct catgaaacgc
     4801 ttttggcctt agatgcgtca acaggtcaaa atgcgcttag ccaagccaag gaattttcaa
     4861 aaataacacc attaacaggt ttgattttaa cgaaaattga tggcacggcc aaaggtggtg
     4921 tagtcctagc catccgtcaa gaattagaca ttccagtcaa ggtcatcgga tttggtgaaa
     4981 aagtggatga tattggagaa ttccactcag aagactttat gaaagggctt ttagaaggta
     5041 ttttataaga aaaaaaccag tcttgttcaa cagaacgagg ctggttttta agtaagtcag
     5101 cttaggctaa tccttttttc cctaaatggt aaaacatagc aaagaaaaag ataaaatcaa
     5161 gtagagcaaa aatagtaaag agaaggtaga cagactggac accgcttgtg aattctggct
     5221 gactattagc tatcagtgat gccatagcag ttcctagagc gccagcaaat tgctgcatca
     5281 tctgaaaaat ggccgtggca tcggcatttt tctcggcagg caattctcga atagccgtgg
     5341 ctaagctatt attaaagccc atgttacgcc caaacgtgaa taaaatatat aaaagagtga
     5401 atggtaaaag cataaaatgt cttgtttgaa gtgtcataat aatcaatgat aaactaaata
     5461 aggcatttcc taaataaagc gaaagtcttg ctcctttttg atcataaagt ttaccaaaag
     5521 caggtgctag tagagctccg agtaaggtac caggtagtaa caccatacca gcttgagaac
     5581 tattagcaat cttttccatg acaataaagt ttggcgttag aaaatttatg cctaaattaa
     5641 tcagctggaa gacaaaaaag ggaatcaggc caaaggttag agagggaatt ttgagaatgc
     5701 gaatatcaag aaagggttgc ttagctgtga gattcttgta gagaaagagg acaaagctga
     5761 gaataaaaag ccctaagtaa tacaaattaa cacttccgtc ttctagacta gtaatagcta
     5821 ataaggcaga agttaagcta atcgatagtg caataaatgc caaccagtca aagggtgctt
     5881 tttctcttac tggagaatct tcgaggtagt aataagctag aatacctgca atcagtggta
     5941 cagggagtat acagataaaa atccattgcc aactaaaatg gctaatcata aagcccccat
     6001 aagtaggccc aaaagcaggt gctaagctaa taataagacc agcaaatccc ataaatagac
     6061 ctaccttatg cattgggaca cgctctaaaa taatattaaa catctgaggc attaccagac
     6121 cagtaccaat gccttgaaaa atgcgggcta gcaacatgat cgcaaaggac tgggtcagaa
     6181 cggccaagat ggtgccaaat gtaaaaagac ctgtggccat aaaaaagagg ggtctttccc
     6241 gcacattttt tttcagtgta gccgaagtgg tcatcataat cgccactgct agtaaataaa
     6301 tggtcgtcat ccattgcaag ctatttaagg gcaactgata gactgacatc agtgtcggga
     6361 aggtgacatt catactggtt tcagacaaaa ttcctgaaaa accaatgagt gctatggcga
     6421 taatcgccat aattgtttgt tttgaaacgg tttgttgatg atgtgacatg ataactcctt
     6481 tatctaatcg attgttattg tatcatataa tcttaaaatt gtcagaaact cttttttgct
     6541 aaatcaatag atacgaataa caatagttgc tctttcagag aatttattga aaacgcttga
     6601 cagaatctta aagagatgat aacattaaag cgttctcaga tgtgattact tcaggtaagc
     6661 aggctagaga cataacaatc agaatattaa aggatgttat cacagttttg tgagcaggga
     6721 cctattcgaa aagtgctttt tagcgagctt ttggataggt cattttttat tgtgatacta
     6781 aaggactagg acttttatgt tgattaaacg cgttttaaac cataatgcgg cgatttcgac
     6841 caaccatcaa ggattagata ttttattgat gggaaaaggg attgcctttg gaaaaaaagt
     6901 tggagatagt attgagctta atgctatcga aacatcattt gttttaaaaa atagtgacaa
     6961 tatgaatcgc ttcacagagt tatttattac ggtgccacaa gaagttgttg cttgctcaga
     7021 gagaattatc aatctaggta aaattaaatt aggcaaaacc ttagatgaaa ttctctatat
     7081 taatttaacg gatcatattc actctgctat tgaaaggcat gagcaaggaa tgttgattca
     7141 taacccacta cggtgggaaa ttcaacgcta ttatcctgat gaatatagtc taggggtaaa
     7201 agccttagag ctaattgagc gtaatctagg agtcactcta gctattgatg aagcagcttt
     7261 tattgccatg cattttgtca atgctagttt ggacactcct tttaaggagc cacatcgcct
     7321 gacggagatt gtttcttata ttgagcaaaa aatcaaaaca gacttcaaaa cagaattgga
     7381 tgacacatcc atcgattatt accgctttat gacccatatt aaattatttg ctcaacgtgt
     7441 gttatcagag atgtcttacg atgatgatga tgcggaactg cttatagtgg tgaaaacgaa
     7501 ataccctaaa gaatatcggt gcgtcttaga tattagtgag gagataaaaa agcggtacaa
     7561 ctatcacctt aattcaagcg aacttttgta tttgacggtt catgttaaac gtttagtgaa
     7621 acatttaaag gagacttaat atgacgtatc aagaaactgc caaggctatt ttagcggcgg
     7681 ttggtggcaa aacaaatatt caacgtgtga cacactgtgt aacacgtcta cgcttagtac
     7741 tgaaaaatga tgagaaagtt aaagatcagc aagtcaaagc catttcaaat gtgattggcg
     7801 tgatgcgcaa aaacggccag taccaaatta tcttgggcaa tgatgtcaat aattattacc
     7861 aagccttttt aagcctaggg cattttgaca atcaagatga agatcattct tcaaaagcga
     7921 aaggaagtat ccttgagcgc ttgattgaaa ccattgctgg cgtgattaca ccgctgattc
     7981 cagcccttct tggtggtgga atgctcaaag tggtggggat cttgcttcct atgcttggct
     8041 tagcgagtgc ggactctcaa accgttgcct ttattaactt ctttggcgat gcggcttatt
     8101 attttatgcc tgtcatgatt gcctattcag cagcggcgcg ctttaaggtg acacctgttt
     8161 tagcagcgac gatcgcaggg attttattgc atcctgcctt tgttgcaatg gtagcagaag
     8221 gtaaaccatt gactttattt ggagcaccag tcactcctgc tagctatggc tcatctgtta
     8281 ttcccatttt gatgatggtt tacttgatgc aatacattga aaaatgggtc aatcgcttgg
     8341 tgccaagcgt gatgaaaagc ttcttacagc caaccttaat cattttgatt tctggctttt
     8401 tggctttagt ggttgtaggt cctcttggtg tgattattgg tcaagggtta tctaatacca
     8461 tgctcgctat ttatcatgtg gctccgtggc tagcacttgc cattttggga gcgattatgc
     8521 cgcttgttgt catgacgggg atgcactggg cttttgcacc aatctttttg gccgcttcag
     8581 tcgcaacacc agatgtcttg attttaccag caatgttggc ttctaatttg gctcaaggag
     8641 ccgcatcttt ggctgttgcc tttaaaacaa agcagaaaca aacacgtcaa gttgcccttg
     8701 ccgcggggat ttcagctttg ctggcaggta tcacggaacc ggcactttat ggggtcacac
     8761 tgaaatttaa aaagccactc tatgcagcca tgatttcagg tggtctggtt ggagccttta
     8821 ttggttttgt caatattgct tcttatacct ttgtcgtacc ttctattatt ggtttaccac
     8881 agtacatcaa cccatcaggc ggagctaatt ttacaaatgc tttgattgcc ggaactgcga
     8941 cgattgtgtt agccttcagt ttgacttggt tcatgggaat tgatgaagag tccccaaagc
     9001 aagtgagtgt tgcagcagat atgtcacaag ttaagagcgg cttgtcaacc aaacaaacgt
     9061 tgtatgctcc aatgacaggt gagatgcttt ttctatcaga agttcctgat gaaacctttt
     9121 cttccaagtt attaggagaa ggatttgcca tattaccaag cgaaggtgag gtctatgccc
     9181 cctttgatgg tgaagtcatc actttctttc caaccaagca tgctgttgcc ttaaaaaacg
     9241 cacgtggtgt ggaagtcttg attcatgtcg gtattgatac ggttgagtta aaagggcaag
     9301 gtttcgagca gttagtgtct gttggcgatg tcgtgaaacg aggccaggca cttctaaaaa
     9361 tggatactga tttcattact tcaaaaggct attcactcat tagtcctgtg gtcgtgacca
     9421 attcggctga gcagttggag attattattc aagatgacaa aaaaatggtg actaaagagg
     9481 acgctttgtt agtcatttta taacctaaaa ggagagggag aatgggaatt tttccaaaag
     9541 atttcttatg gggcggcgca gtagctgcca accaagtgga aggagcattt gaggcagacg
     9601 caaaaggttt gtccgtacaa gatgttctac caaatggtgg actaggagaa tggacagata
     9661 gtcctaccag cgataattta actttagagg cgattgattt ttaccaccgc tacaaagaag
     9721 acattgctct ttttgccgag atgggcttta aagtctttcg aacgtctatt gcttggtctc
     9781 gtatttttcc aaatggtgac gatgaccagc ccaatgaagc aggtttgcaa ttttatgatg
     9841 acttattcga tgaattgttg aactatggca tcgaaccctt agtgaccttg tcgcattatg
     9901 agacacctct gcatttggcc aaagcctata atggttggac agatagacgt ctgattggct
     9961 tttttgagcg ctttgctcag acagtcatgg aacgctataa ggacaaagtc aaatactggt
    10021 tgaccttcaa cgaagtcaac tcgattttac acatgccctt taccagtggt ggcatcatga
    10081 cagaaaaaga aaagctgagc ctgcaagatt tataccaagc tattcatcat gaattggtag
    10141 catctgctag tgtcacaaag ctagcgcatg aaatcaatcc tgatgttaaa gttgggtgta
    10201 tgattttggc gatgcctgct tacccaatga cctctgatcc tcgtgatata cttgctgcgc
    10261 atgcatttga aaatcttaat ctcttatttt cagatattca tgtgagaggc aagtatcctt
    10321 catatattaa gtcgtatttt aaagaaaatg ggattgagat tgtttttgaa gacggagaca
    10381 aggaattatt agcggaacat acggttgatt ttctatcctt tagctattac atgagtgtca
    10441 cacaagctca caatcctgaa gcttacacat ctggtcaggg aaatattcta ggtggtttgt
    10501 ccaatccata tttagaatct tcggagtggg gttggcagat agacccaatt ggtctgcgat
    10561 tggtcttgaa tcagtactat gaccgctacc agattccttt gtttattgtt gaaaatggct
    10621 taggtgcaaa ggatcagctg gtgcaaaccg cagatggcag catgacggtt cacgatgatt
    10681 atcgcattga ctacatgagt cagcatctcg tacaagttgc caaagcgatt gaagatggcg
    10741 ttgaggtcat gggttacact gcttggggct gtattgattg tgtctctatg tcaacagccc
    10801 aattaagtaa gcgctacggt tttatttatg ttgaccgaaa tgatgatggt actggtcaac
    10861 tcacacgcta taagaaaaaa tcatttgatt ggtaccgaca agtcattcaa accaatggac
    10921 gttaccttga ggataatttt tcctaaatag gtcttgttta agatggtgac tctgttccta
    10981 tgctaactga taaaactcaa aaagcatttg ttttgataaa aaacaagtgc ttttttatta
    11041 gtctttaaaa aacgcggtaa acataaggat tattaggttc tttggtttga tgaacctcag
    11101 caagttgaag gacaggtaga tgttgttcta agtttttatc atattccata tgaaggcgac
    11161 ctttaactgt tagccatgtg ttgttagggt agctggtttg attacctgtg gtcaaaagtc
    11221 cgtacactcc tgagtcggca atacagtgaa taatgccgaa gcggaaaagg aattggtagt
    11281 tgtcatggcc cggttcgtta taaacaaagc cagtgtattg gatgtcacga tcaagaaact
    11341 catctgggta gagatagatc aattccataa cttccatata attttcagtg gtaatggtga
    11401 ccggtttctt gcctttatat ttatggagtt cttgacgcat ctccttttgg taggcagact
    11461 ttgtaaagta aaggctagta tcaggcttga ggtattgaat ggtggtaccg tcatcactga
    11521 ctcccgtttt agaggctccc gcagctaaag gaaaagtgta acccttggca gaaaccgtgg
    11581 tggaatctag ggttacggtc ggcacaagga gaccgaccaa gacaggaaag accaagataa
    11641 aaggactcgt cagctttgcg atttttcctg ttaaatggct atgcacctta atgtttttca
    11701 tccaggtata gagttgaaca agagctaaaa tgaaagataa aaccatggaa atataagcaa
    11761 ggtaagaata ccgaacattg atgtactgat ccagtttgcc agacagctgg agatacatgg
    11821 ttagttcaaa atagccagat aaaattaaaa agcgaatcat tagagcaccc ccacaagtaa
    11881 acaataaacg gcaatcataa gaacggatac gccgataaat tggacaatga agcgtccttt
    11941 aaaagccttt accatcatca taaggttttt aatatccacc ataggaccaa ttaaaagaaa
    12001 ggcaagaact ggagccactc caaaggtgga taataaggaa gctccgataa aggcatcggc
    12061 ttcactacat aatgatagaa tgaaagccat cagcatcatg atcaaaatgg ctgtcaaggg
    12121 attgtgccca atcgttgtca acacacgagt tgggacatat atttgcatgg cagaggcaat
    12181 caaggttcca aatacgagat acctaccggt gtcgaagaat tcatcaatag catgtaccag
    12241 tgctagataa atgcgttttg gcaagctttc atgagaataa tcatgaaaat gcacgggttg
    12301 agcattatcc ttgagaatgt tatcatctac aataaaagct aacattaccc caagtgtaat
    12361 ggctactagt gcagcaccga ccaagcgaag tatcagaaag cgcaaagaat tcccaaaagc
    12421 agaataagta gcgaacaaaa caataggatt aataataggc gctgttgcca gaaaagggac
    12481 ggccgtataa ctaggcacct ttttttccaa aaagcggttg atgatgggaa taatcccgca
    12541 ttcacaagaa ggaaaaacaa atccaacaaa ggttccaaac agaatgcgca agcatttttg
    12601 cttaggtagg tatttttgaa ccaattctgg cgttacaaag acttcaatac aaccagataa
    12661 aatagttcct aggagcacaa aaggaagagc ttcaatgata atggacataa aaatcgcaaa
    12721 ccattgcaag acactgggag gaaggttgga aaagagtgac attcaccata tcctttctag
    12781 atgataaaag aggaggctga aacacgaatg ttcagcctcg actgatacgt tttgttagcc
    12841 tgatcgctaa aaatctctca actcagttta aacgaatgga cgatatgtta agagaatgag
    12901 acaaactagc tatggtttgc ttggttttgt ttgttctgtc gttttttctt tggtcgctag
    12961 tttaccatca gtattgactt ccaaaggctt atcaaaacta gggattgatg caaagcctgc
    13021 tagcattttt tcaagttcat catttttttt atgggtaatt gccatatcta tgaccttctt
    13081 tcattcaaga taagtctatt atactatcat ttgagaacaa tgccaaaacg gaagtgttgt
    13141 ttacttcttt cttttttaaa attaggtatt gttatttagg gtttcgtcag ttatttacta
    13201 aaagtagctt tttttgattc tttacgcaac tttatattag gacaatgttt cgctatcatt
    13261 ttttgcatta acatggtttg tgttataata gcaatattat ggaaaataac aataatcaca
    13321 acattgcaga ggctttgtca gttagtctcc atcaaattga acaggtgctt gccctaacag
    13381 cacaaggcaa taccattccc tttattgcac gttaccgtaa agaagtaaca ggaaatctag
    13441 atgaagtggt gattaagtcc attattgata tggataagtc tctcactacc ctgaatgagc
    13501 gcaaagcaac cattctcgct aaaattgagg aacagggaaa actgacagat cagttacgaa
    13561 cgagtattga agcaaccgag aaactcgctg atttggaaga gttgtacctg ccttataagg
    13621 aaaaacgccg tacaaaagcg acgattgcgc gtgaagcagg cttgttccca ttagcacgtt
    13681 tgattttaca aaatgcgcaa aaccttgaaa cagcagcaga accctttgtc acagaaggat
    13741 ttgccagccc acaagaagct ctagcaggag ctgtggacat ccttgtggag gccatgtcag
    13801 aagatgctaa attacgctct tggacctaca atgagatttg gcagtacagc cgcttagtat
    13861 caacgcttaa agatgagcag ttggatgaga aaaaggtttt ccaaatctat tacgattttt
    13921 ctgaccaagt gtctaacatg caaggatatc gtactttagc ccttaaccgt ggcgaaaagt
    13981 taggcatctt aaaagtgtct tttgagcata acttggagaa aatgcaacgc tttttcagtg
    14041 tgcggttcaa agaaaccaac ccttatattg aagaggtcat caatcagacc atcaaaaaga
    14101 aaattgttcc agctatggaa agacgggttc gttcagaact cagtgatgcc gcagaagatg
    14161 gggctatcca cctcttttct gaaaatctcc gtcatctttt gttagtgtct cctttaaaag
    14221 ggaaaatggt tcttgggttt gaccctgcct ttcgaacagg tgcaaaattg gctatcgttg
    14281 atcagactgg aaaattgttg actactcagg ttatttatcc cgtagcacca gctagccaaa
    14341 cgaagattca agcagctaaa gaaacactga ctcagctcat tgagacttac cagattgata
    14401 ttattgccat tgggaacgga acagccagtc gggaaagtga agcctttgta gcagacgttt
    14461 tgaaagattt cccaaatacg tcctatgtca tcgttaacga aagcggtgct tcggtttatt
    14521 cagcgtcaga gttagcccgc catgagtttc cagacctcac agtggagaag cgctctgcta
    14581 tttctattgc tcgtcgcttg caagacccac tagcagaatt ggttaaaatt gatcctaaat
    14641 ctattggcgt cggtcagtac cagcacgatg tgagtcagaa aaagttgagt gagaatcttg
    14701 gttttgttgt ggatactgtg gttaaccaag tcggtgttaa tgtgaacacg gctagtccat
    14761 ctttattagc acatgtgtca ggtttgaaca aaacgatttc agaaaatatt gtcaaatacc
    14821 gcgaagaaaa tggagcactg acatcacgcg ctgacatcaa aaaagtgccg cgtttaggag
    14881 ctaaggcgtt tgagcaagca gcaggttttc tcagaattcc aggagccaaa aatattttag
    14941 acaacacagg agttcacccc gagtcctacc cagcagtcaa agaactcttt aaggtacttg
    15001 gtattcagga cttggacgac gctgccaagg caactttagc agcagttcaa gttccccaaa
    15061 tggcagaaac attggctatt gggcaggaaa cccttaaaga tatcattgct gatctcctta
    15121 aaccaggtcg tgaccttcgt gatgactttg aagcaccaat cttacgtcaa gatatccttg
    15181 atttgaaaga tttggaaatt ggccagaagc ttgaaggaac tgtgagaaac gtcgttgact
    15241 ttggtgcttt tgtagacatt ggtgttcatg aagatgggct tattcacatt tctgaaatga
    15301 gcaaaacctt tgtcaaccac cctagtcaag ttgtttcagt gggtgacttg gtaactgttt
    15361 gggtctctaa gattgacttg gaccgccaca aggtcaatct cagcctattg ccaccgcgtg
    15421 acactcacta attatgtcca agaagtttcc ctggctgatt ttggcaaacc atttcaccac
    15481 aaggcttatt ggaacaagcg cctaaaaaca actggcggtc gcttttttcc aaaagatggt
    15541 catttggatt ttaaccctag gatgcttgag gagcacggtg agcttatttt tcggaaaatt
    15601 gttcgccatg agctctgcca ttaccatctt tattttgaag gaagagggta ccatcataaa
    15661 gatagggatt tcaaagatct gctagctcaa gtaaacgggc ttcgttatgt cccaactagc
    15721 tctaaatcaa agactaatca tcattatagt tgccaaacct gtgggcaggt ttatcaacga
    15781 aaaaggcgta tcaatctggc taaatatgtt tgtggaaatt gccacgggaa acttatggaa
    15841 aaaaatcagt cgtaagactg gttttatttt gcgaaaaaca atgtaaacta gtatcataga
    15901 atgaggaggt aaagaaacgt ggaaactaaa ttctataaac agcgaaaaaa tcgcttggtt
    15961 gcaggtgtca ttgctggttt agcagataag tatggttggg atcttgctct agcgcgtgtc
    16021 ttagcggctc ttcttattta cggaactggt tttggagttt tgctttatat tttgttggcc
    16081 atcttcttac cttacaagga agacttgctt gaagaacgtt atggccgagg tcctcgtcgt
    16141 cgtaaagacg ctgatgtctt aaatgaagaa gaagatggct ggttctggta aacaatcagt
    16201 taaaatgata attcatcacg taagagcaac catgtgatta actgatgata ataaaatgtt
    16261 ttgatatgta agtaagcgag gggtcttatc agctatgatg aggctttttg ctttttgact
    16321 tagtaagatg ataccttttt aaataccata ataagcacta attgctcaat gatactagta
    16381 aagtatttgt ttgccattgt cttatttttg actcatatct ctaaatgata aaacctagtt
    16441 tttaatagag ctaagaccat ttttggtgtc gttgttctca tttagtagtg aaaaaatgag
    16501 tatttgcaag ggtctaacgg tcgatttgtg ttataatatt gaaaaaggag aaattatgac
    16561 cgttactgta aagatgctag tgcaaaaagt taaacttgat gtggtttatg ctacagataa
    16621 cttgctgtca aaagagataa caacatcaga tatttcacgt ccaggtcttg aaatgactgg
    16681 ttattttgat tattatgctc cagaaaggtt gcagctattt ggaatgaaag agtggtctta
    16741 tcttacacag atgacttctc acaaccgtta ttctgtttta aaagagatgt tcaaaaagga
    16801 cactcctgca gtggttgtct ctagaaattt agccattcca aaagaaatgg ttcaagctgc
    16861 aaaagaagaa ggtatttcac ttttaagtag ccgtgtttca actagccgct tagctggaga
    16921 aatgtcttat tttcttgacg cttctttagc tgaacgtact agtgttcacg gcgttttaat
    16981 ggatatttat ggtatggggg ttcttatcca aggggattct ggaattggta aaagtgagac
    17041 tggtttagaa ttagttaagc gagggcatcg tttggttgca gatgaccgtg tggatgtcta
    17101 tgccaaagat gaagaaaccc tctggggaga gccagcagag atcttgcgcc acttgcttga
    17161 aattcgtggg gtaggtatta ttgatgtgat gtcgctttat ggagctagtg ctgtgaagga
    17221 ctcatcacaa gttcaattgg ccatttacct tgaaaacttt gaggctggta aagtttttga
    17281 tcgtctcgga aacggtaatg aggagataac tttctcagga gtgagaatcc ctcgtattcg
    17341 tattccggta aaaacaggtc gaaatgtttc agtggttatt gaagccgctg cgatgaatca
    17401 tcgggctaaa gaaatgggct ttgatgctac aaaaactttt gaagatcgtt taactcaact
    17461 aatcaccaaa aatgaggtga gtcaatgatc aatcccattg ccttaaaatg tggtccacta
    17521 gccatccact ggtatgcgct atgtatcttg tcaggacttg ttttggcggt ttacttagca
    17581 tcaaaagaag cacccaaaaa aggaatatca tctgacgcta ttttcgattt tattctgatt
    17641 gcttttccac ttgctattgt tggtgcaaga atttactatg ttatttttga atggtcttat
    17701 tatgtcaagc atttagatga aatcatagcc atttggaatg gcggtattgc tatttatggc
    17761 ggtctcatta caggagctct tgtacttttg gcttactgtt ataacaaggt gctcaatccc
    17821 attcattttt tagatattgc cgcaccaagt gtcatggtcg ctcaagctat cggtcgctgg
    17881 ggaaatttta tcaaccaaga agcctatggt aaagctgtga gccagttaaa ttacttacca
    17941 agctttattc aaaagcaaat gtttatagag ggaagttacc gcattccgac ctttctctat
    18001 gaatcacttt ggaatctttt gggatttgtc attattatga tgtggcgtcg taagccaaaa
    18061 agtctattag atggagaaat ctttgcattt tacttaattt ggtatggtag tggaagacta
    18121 gtcattgaag gtatgcgaac agatagtctt atgtttttag gtattcgcat ctcccaatat
    18181 gtgtctgcct tattaattat tattggctta atctttgtca taaaaagacg ccgtcaaaaa
    18241 ggaatttctt attatcaaga ataaggatag aaaaaggaga aacttatgga cttagttgga
    18301 atctcactga tgattattgc actcgcattt gttgctttgg tgattttctt gattattgta
    18361 ttaaagaaag tctcagaaac aattgatgaa gccaaaaaaa cgatttctgt attgacaagt
    18421 gatgttaatg tgacacttca tcaaactaat gatattttag caaaagctaa tatccttgtt
    18481 gaagatgtta atggtaaagt agcaaccata gatccactgt ttgttgctat tgctgatttg
    18541 tcagaaagtc tttcagattt aaatagtcaa gcaaggcatt ttgggcaaaa agcaactaat
    18601 gctacaggta atgtttcaaa agctggaaaa ttagcattag ttggtaaagt agcctcaaaa
    18661 gtatttggaa aaaaaggaga aaagcatgaa taaaagtttc aaaaacttag tgattggagc
    18721 tgtttcagga gtagcggcag cttacttctt atcaacagaa aaaggcaagg ctttgaaaaa
    18781 tcgtgctgaa aaagcttatc aagcctacaa agaaagtcca gatgattacc accaatttgc
    18841 taaagaaaaa ggtagtgaat acagccattt agcacgtgac actttttatg atgtgagaga
    18901 taagttggct tctggtgact taactaaaga ggacatgtta gacttgctca aagataaaac
    18961 aacagctttc gtgcaaaaaa caaaagaaac ttttgccgaa gttgaagcga aagaaaagca
    19021 agatgatgtt atcattgatt taaatgaaga cgacatcatc attgactata ctgaacaaga
    19081 tgagcctgtt agtgatacat tagacaaaca ctaactaaaa cgatctaaaa catagaagaa
    19141 gaaaagattg aaggatctga tcactagtcc cgatggttag ttttaggcta actgaagaag
    19201 ggggggattg tggcttcaat ctttttttgt ttttggcaaa agaaaaagag tcatacaaaa
    19261 tggactctgg aagttacatc agtaatgatt tgataacctt ggctaataag gaagtaatgc
    19321 ctaagctgat gatgcttgca aataagaaag caaacattgg cgctaaattc attacgagca
    19381 ggacaaatgc aaataaaacg gtaataaggc tgaaactagc gatacgagca aagaagacta
    19441 attcttttag ctttgcactt tggccattga actcttgaaa atctcgaaat ttactttgag
    19501 attcttggta agaatcatcc tgttcaaccg aattatgctt ctttaacggt gcaggcatag
    19561 tcctctcctt tccttaacat actaagtaat tctatcataa aagtctcttc ttgtcatctt
    19621 tttttaaaag atttgaaaag atttactaat gacaagtgac ttatcatgct ataacagtaa
    19681 ggggactagc ttaacgtttg ggcttttgca agaaatatgc ttaaggtctt aaaatttttg
    19741 gtataataaa gcttatatgg aaaaaataat tattacagcc acagctgaaa gcattgagca
    19801 agtcaaagct ttattagctg ctggtgttga tcgtatttat gttggtgaag ccaattacgg
    19861 gttacgtctt ccccataatt tttcttatga tgaattgaga caaattgcca aactagtgca
    19921 tgatgcaggc aaagagttga cagtagcttg caatgctttg atgcatcaag atatgatgga
    19981 tcagatcaaa ccctttttag acttaatgat agagattgct gttgattatc ttgtggttgg
    20041 tgatgcaggt gtgttttatg tcaataaaag ggatggctat aactttaaac tgatttatga
    20101 tacctctgtt tttgtgactt ctagccgtca ggtaaatttc tgggggcaac atggtgctgt
    20161 tgaaagtgtt ttagcaaggg aaatcccatc agcagagtta ttcaccttag ctgaaaattt
    20221 ggaatttcca gcagaggtgc tagtttacgg cgcctcggtg attcatcact cgaaacgtcc
    20281 cttgctagaa aattattacc attttacaaa gattgatgat gaggttagtc gtgaacgagg
    20341 acttttcttg gcagaaccag gagatgctag cagccattac tccatttatg aagacaatca
    20401 tggcactcat attttcatta ataacgatat cgacatgatg tctaaattgg gtgagctgta
    20461 tgcgcatggc ttaactcatt ggaagctaga tggcatttac tgtccaggtg atgattttgt
    20521 cgctattact aaattgttta ttcaggctaa aaccttatta gaagctgggc aatttaccca
    20581 agaagaagct gaaaagcttg atcaagcagt gcatgcccat catccagctg gccgtggatt
    20641 agatactggc ttttatgagt tcgatccaaa aaccgttaaa taagtaatcc ttgtcttgag
    20701 tgagtttact atttcagggc aagacagggt tatgacacca ttacacaggt aatctaccta
    20761 tcttgaaaat agaaagaata tcacatgtca catatgaaaa aacgtcccga ggtcttatca
    20821 cctgctggaa cacttgaaaa attaaaagtt gcgattgact atggcgcaga tgctgttttt
    20881 gttggagggc aggcctatgg cctaagaagc cgcgctggta acttctctat ggaagaattg
    20941 caagaaggca ttgattatgc acatgcgcgt ggagctaagg tctatgttgc tgctaacatg
    21001 gttacccacg aagggaacga aattggtgcg ggcgagtggt ttcgtcaact gcgtgatatg
    21061 gggcttgatg cggtcattgt ttcagatcca gccttgattg ttatttgttc aacagaagcc
    21121 ccaggtttgg aaattcattt gtcaacgcaa gcttcatcta ccaattacga gacctttgaa
    21181 ttttggaaag ccatgggctt gacacgtgtt gttttagctc gcgaggttaa tatggccgag
    21241 ttagcagaaa tccgtaagcg gacagatgtg gaaattgaag cctttgtcca tggagccatg
    21301 tgtatttctt attcaggccg ctgtgttttg tcaaaccaca tgagttaccg tgatgccaac
    21361 aggggcggct gctcacagtc ttgccgctgg aagtatgatt tgtatgacat gccatttgga
    21421 ggagagcgcc gctccttaaa aggggaaatt ccagaagact attctatgtc ctctgttgac
    21481 atgtgtatga ttgaccatat tcctgacctg attgaaaatg gggttgatag cttaaaaatt
    21541 gaaggccgaa tgaaatctat ccactacgtc tcaaccgtaa ccaactgtta caaggcggct
    21601 gtagatgctt acatggaaag cccagaagct ttttatgcta tcaaagagga attgattgac
    21661 gagttgtgga aggttgccca gcgcgagttg gctacaggtt tttactatgg tatcccaact
    21721 gaaaatgaac aattatttgg tgctcgccgc aaaattccac aatataaatt tgtcggagaa
    21781 gtagttgcct ttgattcagc tagcatgaca gcgaccattc gtcaacgtaa tgtcatcatg
    21841 gaaggcgatc ggattgaatg ttatggacca ggtttccgtc attttgaaac ggttgttaag
    21901 gacttacatg atgcggatgg ccaaaagatt gaccgtgccc caaatccaat ggaactctta
    21961 accatctctt taccgataga agttaagcca ggggatatga ttagggcttg caaggaaggc
    22021 cttgtcaacc tctatcaaaa agatggcacc agtaaaactg ttagaacata gtaacaagaa
    22081 atactagagg ccctcttttt ccaaatggta tacgaccata gttgggaaaa gagagcctgt
    22141 ttttttttga aaattggata tcacaatagc ttattttctc aaaacttgat agaataatag
    22201 gagaatgagt cataaaaaaa gtgaaaaaaa gatgattttt tccactttaa tttcgaatag
    22261 tatagatgag gaggaaaact aatggcagaa tttacattca acattgagga acatttactc
    22321 accttatcag aaaatgataa aggttggacg aaagaattga accgcgtcag ctttaatggc
    22381 gcagaagcga aatgggatat ccgcacgtgg agtccagacc atacgaaaat ggggaaaggc
    22441 attactctta ctaatgaaga atttaaaacc atcttagacg cttttcgtaa gtaatgttac
    22501 cttaatcgaa acataatccc tcgttcgccc ttttcctttt aacctggtta tgacatcgct
    22561 aggttaaaag gacaggggcg aatagaagga ttattttttt gaattgaggc gatcagcaag
    22621 gccgacaagt accaaaatta agcctagccc aagaaaaatc catttggcag ctaaaaggcc
    22681 ataaagcaag aagatagcag cactaatgta ggagatatat tctttggtca tcttgttaag
    22741 tcactttcta taagctactg ttaataaacc agtcttcatg gtaatgaaga ctggttagag
    22801 ataataaaac gttatgttat attgccactt atcggtttta agatatgaat acaaatctta
    22861 aaaaagttaa ggtttcatcg ttggaaataa aagcacatct ctgattgttg ttgtgtttgt
    22921 taataacatg caaagacgat caatcccgat tccgagtcca ccggttggcg gcataccata
    22981 ttcaagagct tcaacgaagt cgtagtcaat gccagttgct tcgtcatcac caagttcttt
    23041 agcttgtgct tgtgcttcaa aacgagataa ttgatcaatg ggatcattca actctgtgaa
    23101 agcattggcg tattctttgg tcatgatgaa aagttcgaag cggtcggtga agcgggtatc
    23161 ttctggattc ttcttagcca aaggcgatac ttcaacagga tgaccaaaca caaaggttgg
    23221 ttggaacaag gtttcttcaa caaattcctc gaagaaagcg ttgatgatat gtccgacact
    23281 tgtgaagtgt ttttcgagtg ggacctgttt ttctttggca agtgcaatag cttcttcgac
    23341 agtcatttca ggccagaaat caacacctgt cacttccttg atagcatcta ccatgtgaac
    23401 acgtttgaaa ggttcattga tacggatttc agttccttga taatcaatag ggccatcatc
    23461 tttaacagct ttagcagcat gttggataat gccttctgtc aggttcatga tatcaagata
    23521 gtctgcatag gcttggtaaa cctcaataga agtgaactca ggattatgag tagcatccat
    23581 tccctcgtta cggaagatac gaccaatttc atagacacgt tccataccac caacaatcaa
    23641 acgtttcaaa tgaagttctg ttgcgatacg aagcaccata tcaatgtttt gagcattatg
    23701 gtgagtaacg aaaggacgag cagcagcacc accagcctcg ttatgaagca caggcgtttc
    23761 tacttctagg aaatcaagac cgtctaaata acgacggatt tctgaaatca ttttggaacg
    23821 ggtcacgaag cggtcaaagc tttcacgatt tgaaattaaa tcaaggtgac gcttacggta
    23881 aatggtttca atatcagtta atccgtggaa tttttcagga agaggacgaa gtgatttaga
    23941 aaggtgagtc aacttggttg ccttgattga caactcgccc atgtctgtac gcatgacttc
    24001 gccttcaacg ccgataaagt cgcctaaatc ggcttttttg aagatttcat agttgtcttc
    24061 gccaacagag tccttgcgaa cataaagttg gatttggcct tcacggtctt gaagatgagc
    24121 aaaaccaacc ttacctttgc cacgttttgt catcaagcgg ccagcaacaa tagctgtttc
    24181 gtttaactca tgtaattctt cttttgtttt atcagcatac ttttctttta attcagcaga
    24241 attggctgtg cggtcaaagc gtttaccgaa aggatcaatt ccttgttcag ccagagccat
    24301 catcttttca cgacggacaa tctgttggtc atttaattct tcgatgtgtt gattagacat
    24361 attttcctcc aatacgattt cctttccatt gtatcataaa agaggctaga atacacctat
    24421 atttcgttgg aaaatgcgac tgcagcgggg cacttttttg aaaataaaat tgaaaagcct
    24481 aatggaaaat agtataatga ttgggatatt aaactagaaa agaaaagaga ctcatgatta
    24541 ctgctattgt ttttgatgtg gatgacacaa tttacgacca gcaagcgcct tatcgaatcg
    24601 ccatggaaaa gtgcttccca gattttgata tgtcagtaat gaatcaagct tatattcgct
    24661 ttcgtcatta ttcagatgtt ggattcccaa gagtaatggc aggggagtgg accacagaat
    24721 atttccgatt ctggcgttgc aaggaaacac tgcttgagtt tggctatcga gaaatcgacg
    24781 aagctgcggg agtacatttt caagaagtct atgagcacga acttgagaac attaccatgt
    24841 tagatgagat gcgcatgacc cttgactttt taaaatcaaa gaatgttcct atggggatta
    24901 ttaccaatgg gccaacagaa catcagctga aaaaagttcg taaattaggg ctttatgatt
    24961 atattgatcc taagcgtgtc attgtgagcc aagcaacagg ctttcaaaaa ccagaaaaag
    25021 aaatttttaa cctggcagca gaacaatttg acatgaaccc acaaaccaca ctatatgttg
    25081 gggactctta tgacaatgat atcatgggtg cctttaatgg tggttggcat tccatgtggt
    25141 ttaatcatag aagtcgtcag ctaaaaccag gaactaagcc tgtttatgat gtggctattg
    25201 ataactttga acagctcttt ggtgccgtta aagtactctt tgatttacct gataataaat
    25261 ttatttttga tattaatgac aagaaaaatc caattttaca gatgggaatc aataatggct
    25321 tgatgatggc agcagagcgt ttacttgaaa gcaacatgag cattgacaag gtggttatct
    25381 tgcttcggtt aaccaagcaa caagaaaaag ttttgcgctt aaaatatgcc agatagatga
    25441 aaccataata gcccactaga taataataaa aaaagctagc aaagtgagtg tcttgtcagt
    25501 aagagatcaa tgtgttagct ttttttatta ttttctagtg gttttacacc tctagaaaag
    25561 atttatcatt ccaaattaaa cagtcataag ttaaataatc tttagtttca agaatagtaa
    25621 gactggcatt atctaagcca cctttagcga gtaaaagagc aggttcaaaa cctaataatg
    25681 agcgaatagt tgctgttaag ttagcgccgt gtcctacaat aagaacgttt tgataatgtt
    25741 tatctttaaa cgattggata agatggcaga cacgttgagt cgtttggtaa attgattcag
    25801 cctcgaactg atctggtttg aactgggcta gattctcccg aaaagccagc atttgttggg
    25861 gatatatagc tgccattgtt gctattttag ccccttccaa tttacctaat ctccactccc
    25921 gaagctggtc ggtgtggtaa agttttggct gttggtcaaa agcatctaag ataatagctg
    25981 ctgttgccat agctctttga aggtcgctag tataaacggc atcaaaagcc accttagcta
    26041 actctttgcc aagtaagtga atttcgtctt ttgcctcttc aagtaatggc gaatcgcccc
    26101 cagcgccttg aaagcgacct tctaaattcc aaagggtttt cccatgtctt acaaaatata
    26161 atttcattta agcctccttt tagagataac tgatgcgagc gctaaaaata aaaaagtaac
    26221 cagaaaaagt ttaggcatca ccaagcaaaa ataataccta tagtgaaaag ataaagtaaa
    26281 aaagcgtagt ataagtgtat aatagctagg ttctgattaa agtgtaaagc ccatattaga
    26341 tctaagacaa atcgacctga atttgtcgtg atatcaagtc tctacaaaag aaaaagatta
    26401 acaggatcaa tgttaaagca gttgagatca aaataatact aaacaaagac tagcttaatc
    26461 aaggcgaaaa acttaaaaaa gaaaccagat aaagttggca gtagtgttca ttttctcttc
    26521 tttaaatcag caaagcttgc gccaacgaaa tcagctagag cctggctaga aatctttata
    26581 gaacgcccaa cttcaccagc tgaaacgatt atttgacctt tttccagtgc agtttggtca
    26641 ataaaaatag gatatgaatg tttttgacga atcccaacag gattattggc accgtgaata
    26701 tagcctgttg tcttttgcaa gtctttttga ggaaccatgg acactttttt gttacctgat
    26761 acttttgcca attgtttttc tgataagtgt tctgttaatg gaataatgcc aattagagga
    26821 cctgtttgat caccagtcag agcaagtgtc ttgtaaatat ctgatggttg aagatcatct
    26881 ggaaagtcgc cttctaaagc attaagcttg agtccttgat gagcaatatt agccttatcg
    26941 aggatttgtt ctactaaggt ttttttgagt tttgtttttt tagccatatc aagtccttac
    27001 ctttatctaa acataaaaaa aatggtataa caacattatt ataccatttt tttaatgtaa
    27061 gattcaaatg actaaaaatt agtctttggg atcaaataat tgaggatgaa ttggtaaagc
    27121 aatcattaac gctaaacatg ttattaaaaa agttaggaca ccagctgtac cattaacgct
    27181 aaaagaatac cagacagcgg acatgccttt aggggcgtaa ctgccccaga aaatgattcc
    27241 tgcaaggaag tgccacaagt aacgtactgt aacggctagt aaactagcca ttattgcaag
    27301 aaaaacggca aaaaaggttt gttgtcttct taaagtttta atcaaactat cagagaaact
    27361 accggctaat cccatagagg taaaggctaa gatatattca ataaagactt gggacatgct
    27421 gagatagtaa acttttccaa gtacaaagtg aagtagcccc caaatgagac ccgccaacat
    27481 gccgtacttt aacccgcggc gcaaagagaa aataaccagt gcaatagcac cataagaagg
    27541 actaaaccag ccagcaaaat ctggaataaa tgaaagggtc atcgccaatg cagcaaaaat
    27601 agcagcttcg ataaggtatt tgacattggt gtttggtgac ataaaaaact ccttttgtgc
    27661 acaaaaagag tatcgctttc caatcattga ttattggtca caatccctac gcttgtacta
    27721 acaagatcag gtcctcagga tttcgcaatt gcgatctcag ccaaagcact cctttgtgaa
    27781 atattatagt cctttcatta tatgatgaga taatctcctt gtcaaggata aggggtttta
    27841 aattattgac ctagagtttt tcttggtaag atgtaaacta taaaaaaaga ttagccatga
    27901 tgctaacctc ttaattgttg gagttgccaa ataacttctc aaacgttttt ttagtgtctt
    27961 ttgttacggc aatttgattt aaatctaaag cattgttaaa accactgaga taaccttgtg
    28021 aggtatattg gtgtaaatcg taatctaagg ttgtattagg agcagcctca taatagccag
    28081 aatcactacc ataagtcgga atccatacag catcgaaacc ttttgttgaa atatcttgtt
    28141 ctgccataaa gtaagttcca atatagagac caacattttc agcaccaagt tttttaagct
    28201 cttctcggaa ggctgttacg cctttattca tatctttcat agtggcttct tcgacatcaa
    28261 tccagtagta agttggatta tagggagcag cgtttttgta gaaagctcgg gcctcttctt
    28321 tcatctcttt agtactacga ccaagtgcgt aactgtaaac agctacagga acatttcgtt
    28381 tttgaaattc tttgatatgc gttttaaaag atttgtcaat tccagttgta aaagcagcgt
    28441 tgttatgagc tgtaatttgc gatcctccat agacacgtac aattgcgcca gagatgtgac
    28501 gtgacaatgt gtcataatca atttcttcag ggagttgcca gccggaaaca tcaacaatag
    28561 gatttaaaat aaagtcttcg gtttcagaag tgctaatttt tgctttacta ggattactgg
    28621 ttgcaatagg aatatgactc ttagcgtctt caacttcttt ttgtttcgca tgattagctt
    28681 gtctttttcc gataatcaat accattgcca gtaaaataaa gaagactagc acaacaatag
    28741 gttttatttt tcttctcatt aactgttatt gtaccctaat tactaaaaaa aatcaaaata
    28801 tcctaactgt tttcttatat tgtcttgcat tttaaggtat tatcttttag aagttacaaa
    28861 tgagatcctc tctaactatg tcaagtttat gtcactatct cttatagttg gtagctatat
    28921 tctttacaat attagtttag tctttgacta tatcatgaca gtcagcaagt actgttttgt
    28981 tatttaattc tcatgttatt atcatttgat aaataagtga gctccaaact ggtaaacgct
    29041 ttgtaaatct gtcataatag agaaaaaaac gaggaagaag tttatgtcag ctaagcttat
    29101 gagtcgcatt gctatcatgt cagccctatg tgttgtgttg agaatggttt ttagcagcct
    29161 gcctaacgtg cagcctgtga cggcattttt actcagttat cttctttact ttgggttagc
    29221 cgaggctgta ttagttatga tgttgtgctt atttttatca gcctttttgc tgggatttgg
    29281 cccttgggtc ttttggcaag ttacttgttt tgtgcttgtt cttttattat ggcgttttgt
    29341 cttgtaccct ctgtctcagc aattccccaa atatcagctt ggttatcagg ctttcttggc
    29401 cgccttatgt ggcctccttt atggggtgtt gatagatact tgttttgcgt atttgtatag
    29461 tatgccttgg tggagctatg ttctagctgg gatgcccttt aatatagcgc atgctttatc
    29521 aactctcgtc ttttttccag ttgtgatgat gttatttagg aggttaatcg gtgaacaaaa
    29581 gatttaaaac aggatttcta gcgcttgttg ctatgctact tgttgcttgc tcgcaaggaa
    29641 caaaacaaac acagactcca agcgttccaa aagcagacca tcacgttcgc ttagttgtca
    29701 aagaagatac caataccatt gatgaaaaag tttcttttgg aaaaggagat acggtgcttg
    29761 aggttctcaa agataattat gaggtcaaag aaaaagatgg ttttatcaca gcaattgatg
    29821 gtatcgagca agacacgaaa gctaacaaat attggctttt taaggtgaat ggaaagacgg
    29881 cagataaggg tgccgatcaa attaccgtta aagatggtga tagcattgaa ttttatcaag
    29941 aagtttttaa atagtaacta taatataaaa tagacttggc acgccaagtc tattttatat
    30001 taaccaagaa gtgctttaag gtcttcttca attagtttag gatctgtctt tgaggaatag
    30061 cgtttaatga cttgaccatt ttggtcaatg agaaatttag tgaaattcca ttcgatgcgt
    30121 ttcccaaggg gaccactttt ttcttctttt aaccaggcaa acaaaggatc agtgtcttta
    30181 ccattcactt tgatttttgc aaagcgaggg aaagtagtgt gataggtcag actgcaaaag
    30241 tgattaatct cctcagcatc tcctggagct tgatttaaaa attggttgca aggaaaatct
    30301 aagacctcaa atcccttgtc atggtatgtg tcatatagtg cttgcaaggc ctggtattgt
    30361 ggggttaatc cacacttggt agctgtgtta acaatcaaaa caaccttttt tttataagca
    30421 gctaaggaaa ggtcattccc gttttgagcc ttaaccgtaa aatcatagag attaggcatg
    30481 tgacatctcc tcggtgtaac tgataatttg gtcaacggta ttactcaaga attgaatggt
    30541 atctcgaaga ggcttttcgg tggcaatgtc tgccccaatg agcattgcag tatcaagagg
    30601 cgtacggctg ccacctgatt ttaggaagtc aagccattct tttgccccat ctgggttgtt
    30661 tttaaggtta aggtaaccag ctgttgacat aacaagccca gcagaatagg tataactata
    30721 taagcccatg tagtaatgcg cttggcgcat ccaggtaaga gctgcgtcat cgtcaatgtc
    30781 aacggcatct ccccagaagt ctgttaagac ctctttcatc atcgcattta attggtcagc
    30841 tccaaaggta ccgccttctt caatcagggt gtaaacctta cgttggaaag ccgcttccaa
    30901 taggtgagtg atgaagttat gaaagtaagt gtctgttaaa cggtgagcaa gggcaaaacg
    30961 tttttgacga gggtcatcaa attgatgttc caagtaatca ctaagcatca attcattaaa
    31021 ggtcgatggc gcttcgacgt aataagttga catatgggtg ttgaagtaac tttggtgatt
    31081 atcagagaaa ataaattggc cagagtgtcc gatttcatga atgagcgtgt agacatcaga
    31141 cattctgcca gtccagctca ttaagacata cggatggacc ttgtaaggat cagcggcata
    31201 accaccagaa tctttattgg cattagcagc aaagtcaacc cagcgttctg tctgataacg
    31261 ttcgatttct ttcgtgtatt cttgtcctaa tggggctaga gatttcatca cgaggtcata
    31321 agcgccatca atgctgacct ctggattgag ctcattatca atatctagtt tccagtcagc
    31381 aaaagtcatt ttctcaagac cattgacttg ggcgacatgt tttaagaatt tctgagcaac
    31441 cggtccaaat tcagtcatga tgaggtcaat ttggcggtcg aacaagctac gatccacttc
    31501 ctgttcagct aggaggtaat caaagacaga agcgtagcct ttcatatcag ctaacaattt
    31561 ttcagattta accttggcca aataagcagc agcagcagta ttttggtgtt tacggagacc
    31621 ttttgagaag gaacggaaag ctttgtcacg aatctcagca ttttcgtgat tttgatagaa
    31681 attttcgtaa gaaacaaagc tatttttata ggttttacca tctacctcaa aatcatccat
    31741 gtcaaagtca ctagcccgca ttttggtgta aatatcatag ggcgcattga taacctcgcg
    31801 taagttagcc aaagcttttt ccacatcagg acttaagagg tgttcctttt gaatttttgc
    31861 catgcgaata gctgcgctga aataagggtt cttttctaat gtatctaaca cgtcaaggtc
    31921 ggcattggct aaggcggtgt caaagaagct aagggcaacg ctagctttag tcatgaaatc
    31981 atcgccagcc tgagcaattt gagcaaaact ttcatctgaa aagtcagtgg tttgaggcat
    32041 aaaggcataa gtgccaatat gactcatttg aatataaata tgctcaattt ctattaaggc
    32101 ctgagtgaaa tcgtccaccg atgttaagcg gccttcataa ttgcgcttaa acaggtcaat
    32161 atcttgtaag gctttttcaa tagcgagtaa aaaatcttgg cggtctttgt agagcgctgt
    32221 tagatcccaa agttcatttt cagggaattc tgaacgtttt ttcaattcca tagttgtctc
    32281 cttaacaata tagtcaagac tagtataaca gaattttagt ggaatatgga gactaaacct
    32341 atccaaacat tctttaaaat aaagcgttta cttttgttaa aaaacaaacg ttatgaacat
    32401 gctcactttt atttttggta aaaagtggta tgatagaaga aactagcaaa gaaggagatg
    32461 gtcatttgcc acttaaaaag ttagagagta gtaacaatca aactatcatt gctgaagaag
    32521 ttgctctttt gaaagaaatg ttggaaaata tcacacgacg gatgattgga gatgatgcgt
    32581 ttacagttat caagtctatt atggtgttat ctgaaaaaca agattacata gaattagaaa
    32641 aagttatcgc caatatttca aatcaagaaa tggaagtgat ttccaggtat ttttctattt
    32701 tacccttgct aatcaatatt tcagaagatg tcgatttagc ctatgaaatt aatcatcaaa
    32761 ataatacaga tactgattat ttaggaaaat tagccctaac catcaaggat cttgctggaa
    32821 aagataatgg taaagacatt ttggagcagg ttaatgtggt tcctgtttta acagcacatc
    32881 cgacgcaagt gcaacgtaaa acgattctgg aattgacaac tcacattcat aaacttctgc
    32941 gcaaataccg tgatgctaag gctggtgtaa ttaatcttga gaaatggcgt caggagctat
    33001 atcgttatat tgaaatgatc atgcagacag atattattcg cgagaaaaag cttcaggtga
    33061 aaaacgagat aaaaaatgtc atgcagtatt acgatggttc cctaattcag gctgtgacca
    33121 agttgacaac agagtacaaa aatttagccc aaaaacacgg tctagagtta gacaatccca
    33181 aacccattac catggggatg tggattggtg gggaccgtga tgggaacccc tttgtcacag
    33241 ctgaaacctt gtgcttgtca gctacggttc aaagtgaggt tatcctcaat tactacattg
    33301 acaaattagc agccctttac cgaacatttt cactgtcgtc aaccttggta caacccaact
    33361 cggaagtgga acgtttagcc agtttgtctc aggaccaatc gatttaccgt ggaaatgaac
    33421 cttatcgcag agcttttcat tatattcaat cgcgtcttaa acaaacacaa attcaactaa
    33481 ctaatcagcc agcagctcgt atgagtagta gtgtgggact aaacacatct gcttggtcct
    33541 caccagctag tttagaaaat cccatcttag cctatgactc tcctgttgat tttaaagctg
    33601 atctaaaggc tattgagcag tcgctacttg ataatggcaa ctccgctttg attgaggggg
    33661 atttgcgaga agtcatgcaa gctgttgata tttttggctt cttcttagca agcattgaca
    33721 tgaggcaaga ctccagtgtc caagaagctt gtgtggcaga gttattaaaa ggagccaata
    33781 ttgttgacga ttatagctct ctttcagaaa ctgaaaaatg cgatgttctc ttacaacaat
    33841 taatggagga gccaagaacc ttatcctcag cggcagttgc taaatcagac ctattagaaa
    33901 aagaactggc tatctatact acggcacgag aattgaaaga taagcttgga gaagaggtta
    33961 ttaagcaaca tattatttca catacagaaa gtgtctctga tatgtttgag ttggccatca
    34021 tgcttaaaga agtgggattg gttgaccagc agcgggctcg tgtgcaaatt gttcccctct
    34081 ttgaaaccat tgaggattta gataatgccc gtgacatcat ggcagcctat ttaagccatg
    34141 acattgtcaa atcttggatt gcaacgaatc gtaattacca agaaatcatg ttaggttatt
    34201 ctgacagtaa taaagatggt ggctacttgg catcgggttg gactctttat aaagctcaga
    34261 atgaattaac ggctattggt gaggaacatg gagtgaaaat caccttcttc catggtcgtg
    34321 gaggaacagt tggtcgagga ggcggccctt cttatgatgc cattacttca caaccttttg
    34381 gttccatcaa agatcggatt cgtctgacag agcaagggga aattattgaa aacaaatacg
    34441 gcaataaaga tgtggcttat taccatttag aaatgttgat ttcagcttct atcaatcgta
    34501 tggtgactca aatgataaca gatcctaatg agattgatag ttttcgagaa atcatggata
    34561 gcattgttgc tgatagcaat atcatttatc gaaaattggt ttttgacaat ccccatttct
    34621 atgattattt ctttgaggca agtccgatta aggaagtttc cagtctcaac attgggtcaa
    34681 gaccagcggc ccgtaaaacg attacggaaa ttacaggctt gcgtgccatt ccttgggttt
    34741 tttcatggtc acaaaatcgc atcatgtttc caggttggta tggggtaggt tcagccttta
    34801 aacgttatat tgaccgagca caaggtaacc ttgaacgcct ccaacatatg tatcagacgt
    34861 ggcctttttt ccattccttg ttatcaaatg ttgatatggt attatctaaa tcaaacatga
    34921 atattgcctt tcagtatgca caactagctg aaagtcagga tgttcgagat gttttttatg
    34981 agattttgga tgagtggcaa ttgacaaaaa atgttattct tgctatccaa gaccatgatg
    35041 atctattgga ggataatcct tcccttaagc atagcttgaa atcacgcttg ccgtatttta
    35101 atgtgttgaa ctatattcaa attgaattga ttaaacgttg gcgtaataat caacttgacg
    35161 aaaatgatga aaaattgatc catacaacta tcaatggcat agcgactggt ttacgtaatt
    35221 caggctaatg ctcttgagta ttaattggta tttatagaag ttttcaagtg actaatcaga
    35281 attttaaagg ttagcccttg gagcttcttt ttttgaggat tcttgacttt ttcttttgtt
    35341 tgatatagaa agatgttata atgctaaatg attatctcaa gaagtagagg gaaaactatg
    35401 aagattgata aaaggcacct cttaaattat tctatattat tgccttattt aattttatcg
    35461 gtgataggct taataatggt ttactcaacc acaagtgtca gcttgattca agcacatgct
    35521 aatccattta aatcggtgat taaccaggga gttttttgga taataagtct agtggctatt
    35581 acatttatct ataaattaaa attaaatttt ttaacgaata caagggtatt aactgtggtt
    35641 atgttaggag aggcctttct tttaattatt gcccgcttct ttacaactgc tatcaaagga
    35701 gcgcatggtt ggattgtgat cggaccagtc agctttcagc ctgctgagta tttaaagatc
    35761 attatggtat ggtatttggc attgaccttt gctaagatcc aaaaaaacat tagcctttat
    35821 gattatcaag cactaactcg tcgaaaatgg tggccaacac aatggaacga tttacgggac
    35881 tggcgtgttt attctttgtt gatggtactt ttggttgctg ctcagcctga cttgggaaat
    35941 gcttccatta ttgtattgac agccattatt atgttttcta tcagtggcat tggttaccga
    36001 tggttttcgg ctatcctagt catgattacc ggcctatcca cggtctttct tgggactatt
    36061 gccgttattg gggtagaaag agttgctaag attcctgttt ttggctatgt cgctaaacgt
    36121 tttagtgcct tttttaatcc ttttcatgac ttgaccgatt caggtcacca attagccaat
    36181 tcttactatg ctatgagtaa tggtgggtgg tttggccaag ggttaggaaa ttccattgaa
    36241 aagcgtggct atttgcctga agcacagaca gactttgtct tttcagttgt cattgaagag
    36301 ttaggtctaa taggagcagg gtttattttg gcacttgttt tcttcttaat tttacgtatt
    36361 atgaatgttg gtattaaagc aaaaaatcct tttaatgcca tgatggcttt aggagtaggc
    36421 ggtatgatgc tcatgcaagt ctttgttaat attggtggta tctcaggctt aattccatct
    36481 actggtgtta ccttcccttt tttgtctcaa ggtggaaata gcttacttgt cttatctgtt
    36541 gcagtgggtt ttgtactaaa tattgatgct agcgaaaagc gagatgatat atttaaagaa
    36601 gctgaattat cttatcgaaa ggacactcga aaagaaaata gtaaagttgt aaatatcaag
    36661 caatttcaat aatattctaa aatctccttt aaggagattt tagaatatag acaatcccag
    36721 tttgatgctc aaaaaacttg aactgctctg ctgatttctt atttttgcgt gtgatatgag
    36781 cccaaacagc tgcttttgct gtggcaaaaa taaggcgtgg aattccaaag gaagtcgctg
    36841 ctataagcac cacctaagga gagtatcgaa aaagactttt tcttctattt aaaaaataaa
    36901 gaaatggcaa aaaacataaa atacttgcat tttcattgta atttgctaca atagtaaggt
    36961 aaagttagac tgtatggcct accgtctatc tataaaatat attttattgg aggcttttcc
    37021 taaaatggca aaagaaaaat acgatcgtag taaaccccac gttaacattg gtacaatcgg
    37081 acacgttgac catggtaaaa ctactttaac agctgcaatc acaactgtat tggcacgtcg
    37141 cttgccttca tcagttaacc aaccaaaaga ttacgcttct atcgatgctg ctccagaaga
    37201 acgcgaacgc ggaatcacta tcaacactgc acacgttgag tacgaaactg caactcgtca
    37261 ctatgcgcac atcgacgctc caggacacgc ggactacgtt aaaaacatga tcactggtgc
    37321 cgctcaaatg gacggagcta tccttgtagt tgcttcaact gatggaccaa tgccacaaac
    37381 tcgtgagcac atccttcttt cacgtcaggt tggtgttaaa caccttatcg tgttcatgaa
    37441 caaagttgac cttgttgatg acgaagagtt gcttgaatta gttgagatgg aaattcgtga
    37501 ccttctttca gaatacgatt tcccaggtga tgaccttcca gttatccaag gttcagctct
    37561 taaagctctt gaaggcgaca ctaaatttga agacatcatc atggaattga tggatactgt
    37621 tgattcatac attccagaac cagaacgcga cactgacaaa ccattgcttc ttccagtcga
    37681 agacgtattc tcaattacag gtcgtggtac agttgcttca ggacgtatcg accgtggtac
    37741 tgttcgtgtc aacgacgaaa tcgaaatcgt tggtatcaaa gaagaaacta aaaaagctgt
    37801 tgttactggt gttgaaatgt tccgtaaaca acttgacgaa ggtcttgcag gagacaacgt
    37861 aggtatcctt cttcgtggtg ttcaacgtga cgaaatcgaa cgtggtcaag ttattgctaa
    37921 accaggttca atcaacccac acactaaatt caaaggtgaa gtatatatcc tttctaaaga
    37981 cgaaggtgga cgtcacactc cattcttcaa caactaccgt ccacaattct acttccgtac
    38041 aactgacgta acaggttcaa tcgaacttcc agcaggtaca gaaatggtta tgcctggtga
    38101 taacgtgaca atcaacgttg agttgatcca cccaatcgcc gtagaacaag gtactacttt
    38161 ctcaatccgt gaaggtggac gtactgttgg ttcaggtatc gtttcagaaa tcgaagctta
    38221 attttaatta agttcccaga atagcaattt aagtcagaca acttaagttt gaagaagccc
    38281 ccaattcggg ggctttttgc tatcttaaac tccataaaat gctgataaat aagaatgaaa
    38341 agctttcaga aaaaagggtt tttatttgtg aaaatattcc taaaatataa gcaattcctt
    38401 ttaatcgtcg gtcatttgtg ctaaaataga agatataaat aaaaaaagaa gaggtatgtg
    38461 atatgtcacg taaaccaatt attgctggta actggaaaat gaacaaaaac cctcaagaag
    38521 caaaagcatt cgttgaggct gtagcaagca aattaccttc aactgacctt gttgatgttg
    38581 ccgtagcagc cccagctgtt gatttggtaa ccactattga agctgctaaa gattcagttc
    38641 ttaaagttgc tgcacaaaac tgctactttg aaaacacagg ggcattcact ggtgaaacat
    38701 caccaaaagt gcttgctgaa atgggagctg actatgttgt gattggtcac tcagaacgcc
    38761 gtgattactt ccatgaaaca gatgaagaca ttaataaaaa agccaaagca atctttgcta
    38821 acggtttaac tccaattgtt tgttgtggtg agtctcttga aacttatgaa gctggtaaag
    38881 ccgttgagtt tgtaggtgcg caagtttcag cagcacttgc aggtctttca gcagagcaag
    38941 tagcttcact tgttttagct tatgagccaa tctgggctat cggtactggt aaatcagcta
    39001 ctcaagatga tgctcaaaac atgtgtaaag ctgttcgtga cgtggtagca gcagactttg
    39061 ggcaagaagt tgctgataaa gttcgcgttc aatacggtgg ttctgtaaaa cctgaaaacg
    39121 ttaaagatta catggcttgt ccagatgttg acggtgccct tgtaggtggc gcatcacttg
    39181 aagctgatag cttccttgct ttgcttgatt tccttaacta agtcatctaa aaaaagaaaa
    39241 ggttaaatcc ttttcttttt tagatgactt aactcttact acgagagaat aaaggtgatt
    39301 ctacaggcaa atgcattagc ctaatagcgg ttcaatagct tttttgccaa tctaatgaaa
    39361 tgatatttga ttggaaatgg ataacatcta aatgttcctg gtttttgcaa aataaagcca
    39421 ttgaaattct gtttaaagcg caagacaccg tctgaaccat caaactttcc agtaatacca
    39481 agaaaattat attgtttgat gcccttgtga attgccttga gcatagcatg ctcttgtaat
    39541 agagctgggc tataaaattt attaaatttg gggtaagatc ctgaaaagag gtagacggcc
    39601 tcttgttcgg tatagataaa aagacttccc gcaaggaaca catctttagt tccgtactct
    39661 tcaagaaaat ggagagcttc agaaattctt acctgaaagg tttcgaattg gctggatagt
    39721 tcttttaatc tattttgctt tttttcagaa tgaggatttt tgccaaggtc tcctttaact
    39781 ttgttgatgc tggttgctag ttgtagttgt ctttgtttaa ggttattaag gtaatcttca
    39841 aaattaagag tcgcaaccat aaattcacaa gagtctccaa aactatcata aaagtcctga
    39901 tagtaagata atgatttgtc aaggtaatct ctacgatcag aggttgcttc agtgatttct
    39961 ttgaaatggt gtaactcatc tcgtttcagt tgacgtaatt taataccaaa agtattagct
    40021 ttttttatta aagcttttcc ttttttgctg aaggaatggg ttaaacgtga ggaatcaatt
    40081 ccttctaact ttttaacgta atgccaaaca ggttcaccct caggatagcc tgtttttaaa
    40141 ccgtcatgtt tatatcctaa cgccgttaaa aggctaataa ggtcagtgtt tggatgagaa
    40201 atagggatgc catcagtatc aaatgactga taattgtcgt aaggttttaa aatgagttcg
    40261 ataacgtctt tttgtttggc atagtcttta agttgagtgt aaaaatgttc taattcttcg
    40321 ggatgattgg tattagggcc tgcattgagt tccatacgcc aacctccagc cactttttgg
    40381 ctaaagacca tagcagcaac ctttagttca ccatcttttt caagtccaag aaattgtggt
    40441 tttgcccctc ttttagccat caagctggcc atttctgagg tttggataaa ggaatgatgg
    40501 acgagactgt ggcagtaatg gtcaaattgt tcttgtgaaa tttcaattag tgccattagt
    40561 tgtgctcctt aatttttttc ttaagttata ggtcaagatg gctaagcttg aaacaaggcc
    40621 gacaggaatg ttgaattcac ctgcaaattc ttcgatggtg gggttgagtc tagctttgaa
    40681 atgatagagt ccaccatctt gttgattttc cacacctcct aaattatgcc agcggcagcc
    40741 tcttttaaaa gcttctttag ccgtttcata ccaggttaaa agaggagctt gataattgcg
    40801 ataatcatcg tccattcccg cataaagatt ttcagaagtc tcgccataaa tcaaggttag
    40861 ggtggcggct agtgggatgc gggttttgcc tgcagcgagc tgctcgctta aaatggttaa
    40921 atctttttgt agccgtgcaa tggttttttg attttctgct actttgctag gtttactctt
    40981 atctgttaat cgtgcttgtt ctgctaaggc cttgtccaac tgttggatca agagtttttt
    41041 ttgttcaggt aagtctaaac tagccatagt aatgtaggac tgaccagcat aaatatctag
    41101 taatttttga tagtaggatt tgcctcggag gataatgcct tttcgattct cggttttttt
    41161 catcaaggct gaaaagtcgt ctagcaattc actgccacca atcgtgacat taacaccttt
    41221 attggtagcg gtacgaatgg attgcttggc ttttttgggc aggctgtcaa agtcaaaatc
    41281 cttggcgtag atgttggctt gtattcttgg ttgaatagtg tcttcgagtt cttttgttct
    41341 gccagaccat tcgacaccga gtttttttag aaaagcaata atagagagtg tcacatcatt
    41401 ttctttgctc tcttttcctt ctaaagtttg tttgatgact aaacttggat caattttgac
    41461 aaaaagcgct cgtttgcttt ttccgacagt tttgagcgtt ttaataacga aatcaaggag
    41521 ttcaaaattg gcgtagtcca tgattggccc acgtgggata taaatcatag tgaaaccaag
    41581 aggaagtttt ctgattaaac aagcagcagc agcaacttgt accccatttt cataaaagct
    41641 gatgcgttcg tgtttccagt tatctttgac ttttccccac tttgaacttt gaagtaagcc
    41701 agcttgtggc tgtgctaaga caaactgatc atgttcttca ggagatattc cgattttata
    41761 tgtatacatt agtttaatac ccacttgcga atagcatgtg ccacaccact gtcattgttg
    41821 gatttggtga tgtatttggc tatttttttc aattcaggaa ccccattttc catgacaaca
    41881 gggttggcaa cgacttctaa catagcacga tcattttcag catccccgat ggccatggtt
    41941 tgtgacatat ctagcctgag ttttttagct aagtgtttga tggcattgcc cttgctgacg
    42001 gtttttggca tgaactctaa ataaaaaggg gttgacttga cgatggtgta cttatcaaag
    42061 aaatgttgag gaatttgctt gatggccgcg tccaaaaggt caggttcatc aatcatcatc
    42121 attttgatga tttctttatt ggtcatttct tcgggagtgc gatagaaaat aggcatgttt
    42181 accaaagtcg attcatgaac tgtgtatttt ccaatattcc gattggcagt gtaaatacct
    42241 tctttggtaa tggcatgcat gtgaactcct aattttcggc tcaaaaattc cgtttccaga
    42301 taatcgtcgt aagtcatcaa ttctttaaca atttcttcgc cggtctcggc atcttgcacc
    42361 aagccaccat taaaagtgat aacgtggttt cctttgtggt tgagttctaa ttgttcgagt
    42421 aatgaaatca ctccggcaat aggtctgcca gtagcaatca ccacatgaac accttgggct
    42481 ttagcttctt ggacagcttg aaaaacatca tctgtaattc gacggtcatc agtgagtaat
    42541 gtgccatcaa tatcgacagc aaccagtttg atagacatgg catcctcctt gtttttttgt
    42601 ggtttatctt aaaaatgttc tccctcctat cttactaaaa ataggtgctt ttgtcatggg
    42661 atgggaaagg aaacttaagg aaaaacgaga gaaaacgttt tagtttagct caatcgcctc
    42721 tgtagtaact aaaaagattg aagaaagtac tctttcttca atcttagact ggagacaaac
    42781 ccagtttgat gctcaaaaag catgaactgc tctgctgatt tgacaactga tttcttattt
    42841 ctgcgtgtga cgtgagccaa aacagctgct ttttgctgtg gcaaaagtgg tgtcgatact
    42901 ggcagtgacg ttacgcgggg tttttgagac cctaggctca aaaataaagc atagaattcc
    42961 aaaggaagtc ctgccataag caccacctaa gaaaagtatc aaaaaagact ttttctgcaa
    43021 tcttaaaggg ctttactgac taaagtgaaa atgcccattg gaaatataac tcataaaagt
    43081 ttccttgcta ggagcaaaga ggtcatcgag ctctaacatc tcctttggaa aataaaagcg
    43141 acggtctccg taggttgtcc ctgttaatgc tttgacaata ggagataact gagataattc
    43201 agcaaggctc ccgtcttttt gtatcatttc aatctgagtt cttggatttt cgagctctgg
    43261 tcgataaata tcataaggca ggtcgaagtt gatatggata ccggtgtaat aatctggatc
    43321 aaagccaact gattcgacca attggcgcaa gcgttctaac tctcctcggg aatcttggtc
    43381 aaaggtaaca gacttcagaa tttttcgatt aataaagcga ctggccaaat ctgataagat
    43441 atggtcttcg cttgccatcc agacttggaa gtaagtattc atgactccgt catctagggc
    43501 tatataatct gctaaattag ccttcttttc aaagaagggg atgagtccag gagctgtttt
    43561 ttggaaataa gcctgttgct caggatataa gtgttgggct cttttgagga gattttgtaa
    43621 gatgagctca acagcacggc tggcgggatg aaaatagacc tgcatgtaca tttgaaaacg
    43681 actgacaata tagtcctcga cagcatgcat accactatgt tcaaagacaa tgccatcttc
    43741 aacaggtcga atcacacgta ggatgcgcat taaatcaaac tgaccgtaat tggcagcaga
    43801 aaaataagaa tctcttaaaa ggtaatccat acggtcgcag tcaatctggc tggaaatcag
    43861 ttgcacaact tgcttgttag gataagtatg attaatcacg ctggcaactt tgtctggaaa
    43921 atcaggagca tgacgcacca aaatggcatt gatttctgtc tcaggattgg taattatctc
    43981 ctgagtaaag gcctcgtgat ccgtatggaa aagggcctca aaggtatgag aataggctcc
    44041 atgaccaatg tcatgtaaga gggcagccgt catagtgacc agactttcat ctttattcca
    44101 gatatcagcg tatttctctt caaaaatagc tgtcacccga cgggcaattt cgtaaacacc
    44161 taggcagtga gaaaaacggc tatgttctgc gccgtggaag gtgaaagctg ttgtagggac
    44221 ttgtttgatg cgtcgtaagc gttggaattc tttggtattg ataaggtcat aaattaatgg
    44281 attatcaatg tggatatagt tgtgaacagg gtcacgaaat actttttcat tcataatttt
    44341 tattatatca aaaattgata aaataaggag aaattgatag aataaacaga cgagcttaga
    44401 atagaaagaa gagttatgaa attacagtta accaaccata ttcgctttgg agatgagaca
    44461 gagattattc aagaaattca tgattgtgag tggcgagaaa aagggggcta tcagtacctc
    44521 atctatcaaa acactgacaa ggaaaaggtt gtcatcaagt ataatgagac agaactgacc
    44581 atgagccgtt tttccaaccc tcagtcaatc atgaaatttt ttgcgggcaa gaaggtcctg
    44641 attgctctac ctacaccgat gggggttcaa caatttttga cagataccag tcattaccac
    44701 ttagattgtt cttgtcaaaa attggacctt cattatcatt tgcttcaagc tcaaacagaa
    44761 atgctatttg caagctatca tcttgagctg agttgggatt aactaaaaag atagcagtaa
    44821 atcatctgat tagggattat tcttgttttt tagtcaggtt tttactataa ttgttattat
    44881 atcaagggag tagcagacgg ctagccgtga ttgtatcgtc aatacggaat ttcggtttcc
    44941 ggtacaatct taaacagcga gacttgttta agaaaaataa acaggtcttt ttatttgaat
    45001 aactaaaata aaaagaccaa ggaggtacta atttgtctaa agaacaaaga catgaagcgt
    45061 tttacacgca aagtgaagag accgtactgg ctcaattaga gaccagtcgc gaaggtctta
    45121 cgtctgccca agcaaaagag cgcttagcag agtatggtcg taatgagctt gatgaaggcg
    45181 aaaaacgaag tttatttatg aaattccttg atcaatttaa ggatttgatg attattattt
    45241 tgattgtggc agcccttctt tcagttctta cagaggggat ggaaggtttg acagacgcca
    45301 ttattatctt ggctgttgtt atcctaaatg ctgcttttgg tgtttaccaa gaaggacaag
    45361 ctgaagctgc tattgaagcc ttgaaatcaa tgtcaagtcc actggctcgt attcgccgtg
    45421 atgggcatgt gactgagata gactctaaag aattggtccc tggagatatt gtcttgctag
    45481 aagcgggaga tgttgtccct gctgatctgc gtcttttgga agctaactcc ttaaaaatcg
    45541 aagaagcagc gcttactgga gaatctgtac cggttgaaaa agacttgtca acggctgttt
    45601 cagaagatgc cggtattggt gatcgcgtca atatgggata tcaaaactca aatgtgacat
    45661 atggtcgtgg gattggggtt atcactaaca ctggcatgta caccgaggtt gggcatattg
    45721 ctggtatgct tgctaatgct gatgagacag atacaccatt gaagcaaaac cttgacaacc
    45781 tttctaagat tttgacttat gcgatccttg tgattgcagc ggtgactttt gctgttggag
    45841 tcttcttgcg tggtcaacac ccgcttgaag gcttgatgac ttcagtagcg cttgccgttg
    45901 cagctattcc agagggactt cctgcgattg ttactgttgt gctttctctt ggaactcaag
    45961 tacttgctaa acgtaacgcc attatccgta aattaccagc tgttgaaacg ctaggatcaa
    46021 ctgaaatcat tgcttctgat aaaacgggta ccttgacaat gaatcaaatg accgtagaaa
    46081 aagtttatac caacggggca cttcaaagtt catcagctga tattgccttt gacaatacga
    46141 cacttcgtgt aatgaacttt gctaatgata ctaaagttga tccttcaggg aagttaattg
    46201 gtgacccaac agaaacagct ttggtacagt ttgggttaga ccacaatttt gacgtacgtg
    46261 aggctatggt ggcagaacct cgtgtggcag aattaccatt tgattctgac cgtaagttga
    46321 tgtcaaccat tcataaacaa gctgatggca aatatttcat cgctgttaaa ggtgcaccag
    46381 atcagttatt gaaacgtgtc acacagattg aagaaaatgg acaaattcgt cctattacgg
    46441 atgctgataa aaaaaccatt cttgatacca ataagagtct tgccaaacaa gctcttcgtg
    46501 tcttgatgat ggcttacaaa tattctgatg ctcttccaac actggaaaca gaaattgttg
    46561 aggctaatct tgtcttctct ggtttggtag gtatgattga ccctgaacgt cctgaagcag
    46621 cacaggctgt taaagtagct aaggaagctg gcattcgtcc aatcatgatt actggtgacc
    46681 accaagatac agcaaaagct attgccaaac gtcttggtat tatcgaagaa gatggcgttg
    46741 atcatgtctt tacaggtgct gaactcaacg aattatcaga tgaagagttc caaaaagtct
    46801 ttaaacaata ttccgtgtat gctcgtgtat ctcctgagca taaagttcgt atcgttaagg
    46861 cttggcaaaa tgaaggcaaa gttgttgcca tgactggtga tggggttaac gatgcaccat
    46921 ctcttaaaac ggcagatatt ggtattggta tgggaattac aggtacagag gtttctaagg
    46981 gagcttctga catggttctt gccgatgata actttgcaac cattatcgtt gcggttgaag
    47041 aaggacgtaa ggtcttctca aatattcaaa aaacaattca atatttactt tctgctaaca
    47101 tggcagaagt ctttaccatc ttccttgcaa ccttgtttgg ttgggatgtg cttcaaccag
    47161 ttcacttgct ttggattaac ttggtaactg ataccttacc agctattgct cttggtgttg
    47221 aacctgctga gcctggtgtg atgaagcata aacctcgtgg acgtaagtca agcttctttg
    47281 atggtggggt gaaggaagcc attctttacc aaggtgcctt ccaaaccatt ttggttcttg
    47341 gggtttatgg ttttgccttg atgttcccag aacacacaag ctaccatgat gttcatgcag
    47401 atgctttgac catggcttat gtgaccctcg gtttgattca gttggtacat gcctacaacg
    47461 tgaaatctgt ttatcaatcc atctttactg ttggattgtt taaaaataaa ttattcaact
    47521 attctattcc agtggccttt gtagcattga tggcaacagt tgttgttcct ggatttaatc
    47581 aattcttcca tgtgacacac ttgacgatca cacaatggtt agtggttatt atcggaagtc
    47641 tcttgatggt tgttcttgtt gaattggtga aagctgttca acgatcactt ggtcaagatg
    47701 aaaaagcaat ttaatagacg ctaaaaggtt tgagacaatt gtctcaaacc tttttttata
    47761 atcgttacaa tgataaggac tattggtatg cctgacatta aaaagttgat tcttgccaat
    47821 tgacttgaca gtcaaaaatt tgttgtttgg cttcttgact gtgaccttca atatcatcga
    47881 ttaaaatctt agtagcctgt tcgccttctt cataggcggg ttggataata gttgttagtg
    47941 ttggtgaaga aaattttgtc cactcaatgt tatcaaatcc tactagtcca atctctggta
    48001 tattaaattt aagagacttc atagctgtaa atacttttgg aagagcccaa caattgggga
    48061 caaaaaccaa actcttttta gtcagtgatc cttgcaaaaa ctgagcaatt gcctctgaag
    48121 aagtctgatt ttcatcaata atcatttctt gatgagtaag atgattagct tctaacacat
    48181 caatgaagcc tgaagcgcgt tcaatacgag tgctaagtaa attggggtta cccgtgatca
    48241 tgataaaatg ttcataacct ttatcgatac attgttgaat ggtatcataa acagcatcat
    48301 aattattagt tttgacccag tttgtgcgat gttcgtaaag ttggctatca aaaaagacaa
    48361 ccttcttttt tttaatatcg ataatacgtg aatattttct aaagttagaa gttggttgaa
    48421 taataaaacc atcaacacca agattgagca tcttttcaat gagttcatct tcgcgagaag
    48481 ggtcgtagtt gctgtttccg atgataattt ggtaaccaaa ttcctgggct ttgctttcaa
    48541 ttcctttgac aatttggttt gaaaaactgt ttgtgatgtc acctataaca acaccaatga
    48601 gtttagttga ttttgcattg agacttctag cagcaatgct cggtttataa ttagtagctt
    48661 tgatactctc gctgatgcgg tttttagttt cttcagacat cttgtcaaac ctgccattta
    48721 agtagaaaga aactgttgtt tttgaagttt tcgctaattc agcaatatct ttgatggtta
    48781 ctttgcgctg cattgcatac actcctttaa aatagtaatg gttagtcata ttataacata
    48841 aggactcgta aaagatttag tgtttcaatc gaataatctc attcgtgata tggttgataa
    48901 caaccacctt tcctctgatt ttatgactat ttaggagaac tagtttttct cctttaatta
    48961 aatcctcttg gagaacacag atactgtagt caaactgctt tccttttaaa tgccaggaaa
    49021 gggcagtctc aattgggttg catttgcctg tttgaagtgg tgttaaggga gtaactttgg
    49081 tatcgtcagg gactaatagg gtactggtgc aacccttgtc tttaaagggt tttcgtttga
    49141 tgagtttgtg actagtcagg tattggttgt atttttttga caaaatcgtt tcttcgatag
    49201 tgaaagggca gtcactgatt agtctgaggt cactaaggtg atctgtcttt acgtctaagt
    49261 gattatcaag aataaattga ctgacaagac agtggttgcc ttgagcctgt atcgtatcaa
    49321 tgataagaaa aattcctggt ggtaagatga gaatttgtcg gtcatgttgg tagttgttcc
    49381 tatcagagaa ttgcgtctgg tagctacctt caataaagta aacgtgtcca ttttgtcgaa
    49441 ggtgacaata attggatttg gggtaagaaa ggtaagccca ggagctatca atctgctcag
    49501 gtaattgttc ttctaagaag gcggtagaat gatggctagc gctttttagg gcatagcgta
    49561 atggttcttc tttgtaagtg tatcgcccag catcacagaa aagtggttgt cctttataat
    49621 agagacagag actattttgg tcgctatggg tatgggaact accgatgggc ccatttttga
    49681 aaaaaagata ataattttct tgattgatgg taatgtgccc ggaatgttca aagtgatgcg
    49741 caaaagttgg taaggtttgg acgggtaact gttcaaaagt gtggacacct ttttctccta
    49801 gaaggagaag actatcgata tcaagtgtgg gaaaagcagc agcttttaag tgtggttctt
    49861 caaggatagt ggctgcaagc gttagaatat ctctggtatc tgtaacatcg ctatcaccaa
    49921 gagggatttg tttatgatct ggaccagtca ttttgaggag ataatcactc atggcaagca
    49981 aagtaggtct aagctgtgga agataatcag ggactagagc agttaattcc agaagggctt
    50041 tgagtacttc cacatgatac atggttgatt gttcaaattg actgccgtct tcgagaattt
    50101 ggagtgcgat ttgttgcgtc aattcttttc tagcgaaagc tgttgctgca gcaatatcaa
    50161 ggtcagaacc aaagtaggca tcagctaata aaatcgcagt ggtttgcaag attccccaat
    50221 tgctgaggct gtatttatca aggtagttgg catggagaaa gtgaagttgt ttttccaggg
    50281 aagctaggat gagcctttcc tcttgcttgg ttaaggcgtc aaaaagatta aggtaaatca
    50341 aacatttgac ccaagcaaaa caacggatgc cagtatctaa ggttctagta gctaacccct
    50401 tagggtctaa aggaatagct gattcaatcc aattgaggat gaaacttttg gcttttagga
    50461 gataccgttc atctctttca acaaggtaga cgaggattaa tgtttggaga taggtctgtc
    50521 gatttaacat aaaattccac tcaggatcat ctgtgacagc ctcttgccaa gtaatgggat
    50581 ctaagtggta agggatgtgg cagggctcca tatcccaatt atcttcaaat aaaaaggtat
    50641 tggttaagag taggtcagct atcctttttc gatcagcata gctgtcagcc tgatagtcta
    50701 gcaggtaatt cctgcaaaag tctggattga ctgtttcttt aaagcgtgcg aaggcaaaaa
    50761 acataggaca tttcctttcc aaaagaaaag agacctgtta atgtgactag gaaatagttc
    50821 ctaaacccat aacagaatct cagtgacaac taagctaaaa tacccaacca actgccaata
    50881 acaccaatga taacagttaa aatgaccaat ttgtaggttg tccatttttt gtttttaatg
    50941 aggtaataca tgagtaaggt aaagagagct ggtaaaagtg caggggcaat cttatcaagc
    51001 attccttgaa tagtcacaaa tttttgtgct gtattggccg catccacctt gccagccgca
    51061 aaagtaatgg gaacagttat tttaacagaa gtagcagcta atccagcgat aacggtaaca
    51121 ccgacaatat ttgccatacg agatactatc gccatttgtt cgcttagttt atcaataaag
    51181 cttgtgccga ctttatagcc atagagacca gaaccgattt taatagcagt taggataata
    51241 ttcatggcta ggaagaagaa aattggacct aaaactaaac catcactagc taaggaagct
    51301 gcaatcgttg aaaagagtgg cgccaagcaa aattgtgata aggagtcacc gataccagct
    51361 aaaggcccca taagtgccat tttgatgttt cgggtttctt cttcaggacg atcattttct
    51421 aacatgacca agtgcagact ggtgatgaaa ggaaggaagt gagggttagt attgtaaaac
    51481 tcacagttat cttctaaagc ttgatataag ccctttttat cactgccaaa atgttttttc
    51541 aaggcaggat agatgacatt ggcgtatccg ataccttggt aattactgta attaaaccca
    51601 ttttgtagga agaaagctct cagagctgtt ttgaggtaat ctttcttggt taatttatta
    51661 gatccagtca tcttgttggc ctccttggac agttgttgca tcgacttgtt taggtttgtt
    51721 gtaaaattca ttcaaggcga aaatgatacc aataatagcg ataccaatgg ttggaatttg
    51781 gaggtaggct ccacaaacat aaccaattag tacaaaagga atcaactcct tcttggccat
    51841 aactgataag atcatggcaa atccgatagc aggtaacatt ttaccagcaa cagtcaatcc
    51901 attgagcaag acaggtggga tataatcaac caagtgaagg agggtatcca ttgacaaggc
    51961 acctaataaa ccaagtccta atccaaggat agcaaaagac caaatggtcc cattagcagc
    52021 gaatttgaag cctctaatat tgcctttttg caattgcttt ttagcggttt caggagcccc
    52081 agcaaaagcg gtataggcga atgtctgaag aaattggatg acaactgcga ttggtgttga
    52141 taaggctagg gctgcttctg gggtaacttt accagcactg gtaatagcca tcaaggtacc
    52201 aaagatacca gggccgatag gattaggtgg aacggtacca ccggcaccca ctccaaatcc
    52261 catataagct aattcggaga tagctcccat gctaagtgca gttggcaagt cacctaagat
    52321 catccctaca ccaaaagaca gaataataca acggttggtg tagatgccaa gtaacattcc
    52381 gctgaaacaa aaggctgtcc aaagaccaat taaaagtgcc tgtaacaaat tgatatccat
    52441 atcaatctcc tttattcatt aaatataatc taagatgtca acgtcagagg cgctattgcc
    52501 agctggagtt gttttggtgt taaaaaccac ttggtggtca tgggctaagc aacgaatagc
    52561 agacttgtct gtttctccca gcgaaataaa ctgggtaatc gcaaccttat catcagtttt
    52621 atgaatatta ccgatattga tttctgtgat gggaacaccc ccttcaacta ggcgtttggc
    52681 atcttgcaaa tctttgacca cgatgaagat actttgagca ggacttgctt tatgaatgat
    52741 gtcaatcact ttttgaatgg agaaaaaacg aatggcaata ctggatggaa taactgtttt
    52801 catgagggat tgttgaatct tatcttcaga aaccgcatcg ttagcgacga taacggtgtt
    52861 gcagttgagg aatttgaccc ataattgccc ctgtccgtga atcaaacgct catcaactcg
    52921 cgtcatgata atgtttggtt gtgtcataaa atctcctttt taaatgtgat tatcggtgtt
    52981 tgttaccagt aagggttcca gtctttgtag aaacgaagca gagcttcaag atagtaatag
    53041 tctccccaga tatttccttc atccacccct tttccagagt gccaagaata gactccgtga
    53101 agcagtagag gagcaccagg cttgagatct ttgttagcat aatccttaat caaggctctt
    53161 agcatgctgt gcatggcagc ttcatatgtt tttttatcag gatcactgtc tggtaaggtt
    53221 tttaacattt catgaatacc acacacagca atggcggttg ctgaactatc acgagactgc
    53281 tcgctaccat ctccaaaaat taaatcccag taggaaacct ggtctttagg aagacggttc
    53341 aagaaataat gggtcatgcc cttgaaaagt tgaataagtt caggttcttt taggaaacga
    53401 taggtcaaag gaatgccata aatgccccaa gattgccctc tggcccaagc cgaatcatcg
    53461 ctataacctt gtcgggttac ccctttaaca ggttcccctg tttctggatc aaagtagaag
    53521 gtgtggtaag cagaggcgtc atctcggatg acatgattgg ctgaggcgta gaaatggttg
    53581 atcgccatgt cacggtaacg gttgtctcca gtttcttggc tagcaaaaaa gagtaattgg
    53641 atgtttagga gacaatcaat gattaaacga taatcttgtt ttttacccag ctccccccag
    53701 gcctgaataa agccgccttt gtcttgatag cgttggacta atttgtcggc cgctttcaaa
    53761 gcagcttctc tagcctcaga agtttttaaa agtttccact cagccatgca agaaggggtg
    53821 taaagaaagc ccaaatcatg gtgatctagc tcaatgtctc ttgttactcg atctaggaaa
    53881 gaaaggtcat ttgcttgagc cagagcttta atggcatcat ctccactgta ttcgtaagct
    53941 aaccagaggc agccagtcca aaaggcattg gtccattccg tgttgtccat aatggtgtat
    54001 tggttatctt tggtagctgg cgttggaaaa tcttctttga agtagtccat gttaagccga
    54061 acttgtttga gggctaagtc aagggcctga gtaatgtctt cttggcttag gaaatctttt
    54121 ttggtaaatc gttcaggctg cttgataggt tcaagagcaa tggtttttaa agatcgtgtc
    54181 attaaatgcc tcctaactca tcgtctgtcg taccgtcttc ttgctgagaa agagtcttcc
    54241 agtcaacaat gccttcttta gaacatgtta taagtcctga tactaagtcg tcaaaagaag
    54301 ctgctgtttg tcttgcaaaa ctagcttcaa tcagcatggc taagttaagg ccagaaagaa
    54361 cattacacgt cgtgtttgaa agagattcca ttaaggttgc agcgacttta aaaggggtac
    54421 ctcctagaag gtcacaaaga actaaggttt cctcttctgg gattaaagca cgagataatt
    54481 ggtcctgcac atcagcggcg gtcatctcag cagtaaaatc aattgcagtt accttctctt
    54541 gttgtcctgc aattaactct agggatgaga caatcccact tgcaaagtgt ccatgtccca
    54601 taacaataat agcaatcata aatagatctc ctttagttta ccggtttact taaaaacatt
    54661 gtagcgcttt caaaattctt tgtcaatact ttttttaaaa gatttttgaa aaagaaaaag
    54721 tgagcagttg tgctaaaaaa gaatcaaaaa tggtcttttt tgtcactatt taatgtagaa
    54781 aagtcttaat agctattaag tataggacaa gactaaacaa gaatgacagt ttggataaga
    54841 gtactctttt aaatttttga accgttttca ttaaaatgat tgacaaaact agtttacttt
    54901 gttatagtct tggtaaacag gtttacttaa tctaataaca aaaaggagaa tcctatggaa
    54961 aatatgtttt cgttacaagg taagattgcc ttgattaccg gagcatccta cggtattggt
    55021 tttgaaattg ccaaagccta tgctcaagcg ggtgcaacta ttgtgtttaa tgacatcaaa
    55081 caagagttag ttgataaggg gttgactgcc tatcgagagt tagggataga agcgcatggc
    55141 tatgtttgtg acgtgactga tgaagctggt atccaacaga tggttagtca aattgaagat
    55201 gaagtaggtg ttattgatat tctggtcaac aatgcaggta ttattagacg tacgccgatg
    55261 cttgaaatgg ccgcagaaga ttttcgtcaa gtcattgata ttgatttaaa tgcacctttt
    55321 attgtgtcaa aagcagtttt gccatcgatg attgcaaaag gacatggtaa aattataaat
    55381 atctgttcta tgatgagtga attgggtcgt gaaacagtta gtgcctacgc ggcggctaaa
    55441 ggtggcttga aaatgttaac caaaaatata gcctctgagt ttggagaagc caacattcaa
    55501 tgtaatggga ttggtcctgg ctacattgcg acgccccaaa cagctccgtt gagagagcga
    55561 caagcagatg gtagtcgtca tccttttgat caatttatca ttgctaaaac accagcagca
    55621 cgttggggga caacagaaga cttagctggt ccagctgttt ttctagctag cgatgccagt
    55681 aattttgtca acggccatat tctttatgtc gacggtggca ttttagctta tattggaaaa
    55741 caaccttaat cacacactag aaagagattt tatatgaaaa ttgcattaat taatgaaaat
    55801 agccaagcgg ctaaaaatgg tatcatttac gatgccctta ccacagtgac agataaacac
    55861 ggctaccaag tctttaacta tggtatgtat ggcacagaag gtgaaagcca gttgacctat
    55921 gttcaaaatg gactcttagc ttctatttta ttgaccacta aggcggctga ttttgtggtg
    55981 actggttgtg ggacaggtgt tggagctatg ttggccttga acagcttccc aggtgttacc
    56041 tgtggttttg cgagtgagcc aacagaagct tatctctttt ctcaaatcaa tggtggtaat
    56101 gccttgtcca ttccttttgc caaaggtttt ggttggggag cagagttgaa tttgacctta
    56161 atatttgaac gcctctttgc agaaccaatg ggtggtggtt accctaaaga gcgagctatt
    56221 cctgaacagc ggaatgcacg tattttaagt gatctgaaaa aaattactta cagagatttg
    56281 ttggcaattg tcaaagacat cgaccaagat ttcctcaaag aaacgatttc tggcgctcat
    56341 tttaaagagt acttctttgc caatgcggag ccgtcagaat tagttactta tttgaaatca
    56401 gtacttgaac agtaattcca ttttgacgag gaaaggagat cacatgtcta agttattatt
    56461 ggttggtgaa ccgctgatac gcgttagtcc caatcagttt cagcctttaa ccaatgcctg
    56521 cgacgctcag ctttttttcg gcggttcaga agttaatatt gcaagaactc taggcggttt
    56581 tggcttagaa gcaaggctat ttacggccct accagataat cctgttggtc acgcttttca
    56641 tcagtttttg aagcaaagcg gtgtggatat gaccttgacg gcttggcagg gcaaccgtgt
    56701 tgggctgtat taccttgaaa atggctttgg ttgtcgttct agtcaggttt attatgaccg
    56761 ctgtggctct agcttttcgg ccttagataa ggatagtctt gatctagctg ccatttttga
    56821 aggcattagt cactttcatt ttagtgggat cagtttggcg ctgggcaaaa aaactcagga
    56881 cctgattgag gtacttgtga gagaagctaa gaaaagggat atttgtgttt cttttgatct
    56941 taactttaga tctagtatga ttgcggtagc tgatgctaaa cgactctttt ctcactttgc
    57001 tcaatacgcg gatattattt ttggcatgga acctttgctg ttagacagtg acgattttga
    57061 catgtttgat aggaataagg cagatgctac gatgattaga gaacgtctgg caggacttta
    57121 tcagcgctat cagttacaag ctatttacca tacggagcgt tcaaatgatg cccaaggcag
    57181 taatcgtttc aaggcttatg cctatgatgg gcagttttac gaatcctgtg aagtgacgac
    57241 cccagtcttg caacgggttg gaagtggaga tgcttttgtg gcgggtttac tttatcagtt
    57301 gttagaaggt aacgaaaagc agtgcaacct tgattttgct gtggcaacag ctagcctaaa
    57361 atgtacagta gctgaagatc agctctatca cagcgtccaa caagtagaag cagtcttaca
    57421 taatcaacga gatgtccaga ggtgatgata tgggaaaaat agaaatctta accaaactta
    57481 aggctaatcg gcttgtcctg gttgtacgag gagagtctag tgaggaagct ttagcttgca
    57541 gcctggccag tattgaaggt ggcattaaga caattgaagt cacctatact aacccctttg
    57601 ctagtgaggt tatcggtcaa ttagctgaac gcttcaaaga agatcctgag gtattgatag
    57661 gtgctgggac agttttggat gatgtcactg cccgccaagc tattttagca ggagcacagt
    57721 ttattgttgg tcctaatttc aatcgagcag tggctttgat ttgtcatcgt tatagcatac
    57781 cttatttacc aggttgtatg acggttaatg aagtggttac agcattagaa tcaggggttg
    57841 atatggtcaa aatttttcct ggttctactg tagggatatc ctttattcgg gcaatcaaat
    57901 ctcctttgcc acaagtagag gttatggtta caggcggagt ttcttcagat aatctcaaag
    57961 actggctagc tgctggagta gatgttctag gtataggagg cgagtttaat cagttagcga
    58021 gccaaaaaca atataaccta atcactaaga aagccgctca ttatatcaaa agtttgcgac
    58081 aataatctaa aaaacgtttt taccttggct ttagtgctag taaaaacgtt tttttatcat
    58141 tcattcaatt aatatgcttc tgcttatgtt tttccagata gtatagatat aagagcagct
    58201 aatttaacaa gatgagcctg tcgtttgata tataggatat aaacttttta tgatcaaaca
    58261 aaagtaatac cttttgaatt cgttagtatt gacctgatct aaagtgatat cacttagaat
    58321 gaactagctg tacagctttt acagcaactt atgctaaaat agaaaaaaag gagaaatgtt
    58381 gatgattaaa ggaattattt ttgatatgga cggtgtttta tttgatacag aaccttttta
    58441 tctgaggcga cgagaagatt tttttaagac aaagggaatt cccattgatc atttgaactc
    58501 taaagatttt attgggggca atcttcaaga attatggaaa gagttgttag gtaaaaatag
    58561 ggatgatgct atcgttaagg caattacaac tgactatgac gcttacaaac aagcgcataa
    58621 gcctccttat caaaaactgt tgattacaga agtgaattct tgtcttgaac agttgaaaaa
    58681 acaaggtatt aaactggctg tggcatcaaa ctcgaagcgt caggatgttt tgttggcgtt
    58741 ggagacaacg caaataaaag attattttga aataatccta gcgcgtgaag atgtttctag
    58801 aggcaaacct tatccagata tctataataa agcagtacaa aaactaggat tacaaaaaaa
    58861 acaactgctt gtagtagaag acagccaaaa aggcattgct gccgccaaag cagccaatct
    58921 gacagttttt gccattaccg actaccgata tggcattgat cagagtcaag ctgatcacaa
    58981 gatagatcat ttaggacaac tgtgtgtaaa aatcggttgt tttggatcgt gaagtaacgc
    59041 aactaactga tcattgatga tacttcaaga cacttaagaa tacgtctagg actttctaca
    59101 gaccaataat aagaatacgt ttatgtgttt ttactgtttt ttagctacct atttacaata
    59161 tgacactgaa aagagtacta tgtttaagtt attatcaaaa aaaccgtcgc ataagatcac
    59221 ctagaaaagg attatgattt ttgtgatttg gatgcgatcg ttagtcgttg atcatcttta
    59281 tgtggcagga gatatgttta accgtggtca ttatttggat ttgtttttag attggctagt
    59341 gagtaaatat agaaggatca taatactgct ttgacaaagg cagtatctga gtccatgagt
    59401 tgcacgggta atgtgactcg gttttggtta ggtataataa tatttggaag tgttatgctg
    59461 cttgtcttcg taggttcatt gcttatagtc agacttactt tagagctgag ctgactgtct
    59521 agacaagacg tgatggagat gtgatttctg accaagtaga ggtaaccaga aaagggactt
    59581 ttacgatgta attgaattta cttgttgcat tcttgtgcat gttaagagag aaaacccaga
    59641 taaatcagga agtaaaacgg ttatgtttga ttagaattgt ccttcttttt ccttgaagtc
    59701 ttaacttatt ttgattatga tagtagtatg actattaagg cagaaattaa ggcactcgcc
    59761 aaagaaattg gtatctctaa aattggtttt acgacggcag ataactttga ttatttggaa
    59821 aagtcattgc gtgcttctgt ggaagagggg cgcaattcag gatttgaaca taaagtcata
    59881 gaggatcgta tctaccctga aaggctttta gaatcggcta aaacgattat ttcaattggt
    59941 gttgcttatc ctcacaaact tcctcagcaa cctcaaaaaa caccttataa acgtggaaaa
    60001 attacaccta gttcgtgggg gcttgattat cattatgtgg tcggcgaaaa gttagacaga
    60061 ctatcaaaag gcattgaaga gctgtgtcga gattttcctt tgcaacaaaa agcaatggtc
    60121 gatactggag ctttagttga tactgcagtt gcccaaagag cgggtattgg ttttatagga
    60181 aaaaatggtc tagttatttc taaagaatat ggctcttata tgtttttggg agaattaatt
    60241 accaatttag agatcgagcc agacaagcct gtcgattatg attgtggtga ctgtcgtcgt
    60301 tgtctagatg cctgtccaac ttcttgttta attggtgatg gctcaatgaa tgccaagcgt
    60361 tgtctatcat ttcaaaccca agataaggga atgatggaca tagagtttcg aaaaaagatt
    60421 aaaacagtta tctatggttg tgatatttgc caaatttgct gtccttataa caagggtata
    60481 aacaattcac cagctacaga gattgatcct gagttggccc aaccagaatt aataccattt
    60541 ttgagtttat caaatggaaa atttaaagaa aaatttggta tgattgctgg aagttggcga
    60601 ggtaaaaata ttttacagcg taatgccatt attgcgctag caaatgctca tgataaaact
    60661 gcagtggtca aattaataga gattattgat aaaaataata accctattca tactgcaaca
    60721 gctatatggg cattgggaga aattgtcaaa aaaccaaacg atgagatact ggcgtttatg
    60781 agtcatttaa ccttaaaaga tgaagatagc cgaaaagagt tggaattaat ccgtcataaa
    60841 tggcaatttt aagcctttta tggtattttt aagaacctta tgataaaata aaacagatta
    60901 acaaagattg gagaaatctc atggaagtgg ctgaaattcg ccaaaaaata gtagaaaata
    60961 aagagaagtt gactagcttc aggaggtctc tttgacttag atcgtttgga agaggagatt
    61021 gctcttcttg aaaatcacat gactgagcca gacttttgga atgacaatat tgcagcgcaa
    61081 aagacatctc aagaactaaa tgagttaaaa ggtaagtatg atactttcca taatatgcaa
    61141 gaattatctg acgaaacaga actcttactt gagatgcttg acgaagatga ttctttgaaa
    61201 gaagaattag aagaaaatct aatgcagcta gataagataa tgggtgctta tgaaatgacg
    61261 cttctcttat ctgaacccta tgaccacaat aatgctatct tagaaatcca tcctggttca
    61321 ggaggaactg aagcgcaaga ttggggagat ttactcttac gaatgtatac ccgttttggc
    61381 aatgctaatg gtttcaaagt agaagtattg gattatcaag caggagatga agctggtatt
    61441 aaatcggtta ccctctcttt tgaaggcccc aatgcttatg gtttgttgaa atcagaaatg
    61501 ggagttcatc gcctcgttcg tatatcacct tttgattcgg ctaaacgtcg tcatacctca
    61561 tttgcttcag ttgaagtgat gccagagtta gatgatacga ttgaagtaga agtacgtgat
    61621 gatgacatta aaatggatac tttccgttcc ggaggagctg gtggtcagaa tgtcaataaa
    61681 gtatcaacag gtgttcgttt gacgcatatt ccaactggaa ttgtggtatc gtctaccgtt
    61741 gaccgtactc aatatgggaa ccgcgatcgc gctatgaaga tgttgcaggc taagctatat
    61801 cagttagaac aagaaaagaa agcacaagaa gtagatgctc tcaagggtga taaaaaagaa
    61861 atcacttggg gaagtcagat tcgttcttat gttttcaccc cttatacgat ggtgaaggat
    61921 catcgtacta actttgagct tgctcaggta gataaggtta tggatggaga aatcaatggc
    61981 tttattgatg cctaccttaa gtggcgcatt gaagactaaa aataataaag gagaaacatg
    62041 gcactaatag aaatgtctgg tgttactaaa aaataccgcc gctcaacgac cgccctcaga
    62101 gacgtcaatg tttctgttaa ccaaggtgag tttgtttatc tcgtaggccc atcaggtgct
    62161 ggtaaatcaa cttttatcaa actcctttac cgtgaagaac aactgacaac tggtaagcta
    62221 tatgtgggtg aattcaattt aactaaacta aaagcacgtg atgttccgat tcttcgtcgt
    62281 cacatcggag tagtttttca agattacaaa ctgctaccaa gaaaaacagt ctttgaaaat
    62341 gtagcttacg ccatggaagt tattggtgaa aagcgccgcc acattaaaaa acgcgtgcca
    62401 gaggtactcg atttagttgg cttgaaacat aagatgcgtt cttttccaag tcagctatca
    62461 ggaggggagc agcaacgtgt ggccattgcg cgtgcgattg ttaataatcc taaattattg
    62521 attgcagatg aaccgacagg gaatttagat cctgagattt catgggaaat tatgcagtta
    62581 cttgaacgta ttaatgttca gggaacaact atcttaatgg cgacacacaa cagtcatatt
    62641 gtgaatacat tccgtcatcg tgttgttgct attgaagatg gtcgcatagt acgtgatgaa
    62701 gaaaaaggag attatggtta cgatgattag atactttttc cgtcatattt gggaatccat
    62761 taaaaatctt aaacgcaact tttggatgac atttgcttca gttagtatgg tggctgttac
    62821 attgacttta gttggtgttt ttgcggcgac attgttgaat atacagcgtg ttgcttcggg
    62881 tgttgaaaat aatgtccata tcaatactta cttacaagtt gattcaactg atgctgcaaa
    62941 agttattcaa aatactgccg gtgaacctgt taataacgat aactaccaca gtgtttacga
    63001 caaaattgct cagataaaag gtgtcaaaaa gattacattt tctagcaagg atgaacaatt
    63061 gaaaaaattg caagaaacct taggtgatgt ttggaatatg tatgaccaag acactaatcc
    63121 gctccaagat atctatctta ttgagaccca gacgcctaaa caagttaagg cgatcactaa
    63181 aaagatcaga acgattgaag gcgtagaagc cgcagattat ggagggatta actccgataa
    63241 actatttaag ttttcaacat taattcaaac ttgggggctg atcggaacag caatgctatt
    63301 atttgtagct gtctttctca tttcaaacac tattcgtatg actattatgt ctcgtaaacg
    63361 cgacattgaa attatgcggt tagttggtgc taaaaattct tatattcgag ggcctttctt
    63421 ttttgaaggg gcttgggttg gcttgttagg agctgtttta ccatctcttc tgatttatta
    63481 tggatatgat cttgtttata agcattttgc acaagaatta caacgtaata atctctcgat
    63541 gtatccgctt gatccttacg tatattacct gattggtgct ttgtttgtca taggtattat
    63601 gattggttcg cttggttcag tgctttctat gagacgttat ttaaaattct aaaaaaagcg
    63661 ctgctgacga aacgtagcga ccctcaaaag ttggacctct tatgttattc caaggacctc
    63721 gttttgtatt gcacaggact ggtccttttc attttgtttt gattcatttg tttatttgta
    63781 ataggcaata cagtttaaaa tagcagtttc taaggtttca agagaagaaa agcaccccaa
    63841 aagttagatg tttgatgtat ctaacttttg gggtatcatt caaaatttag tggctctttt
    63901 ttagtaaaat actatgattt cagttttagg ataacctcaa acagtatcta aaatagctat
    63961 gtcaatgaaa aaaggggtta gcattttttt cgtgacaaat ggtagtagaa ggaccatgcc
    64021 caggataaac tcggtaatga ttaggtaagg tgaatagttc ttggcgaata ccagtaatga
    64081 ggtcctcaaa gttactggta ggtaagtcag tacgaccgat agtttcacga aatagagcat
    64141 cgccagtaac gactaattca tctgagtgga aaacaaatga gactcctccc caagaatgac
    64201 caggtgttgg taaaactgtg aattcaaaac catttagttg atagggttgc tttaatttaa
    64261 aaaagttctc tgccggtctt gctataacag taatgatatc atcatgacgg cctaagccag
    64321 ataaattatc atctggggaa gatagccaag cggcttcttt ttctgaaaca taaacaggtg
    64381 gatgatcaaa agcatctctg accaaatcta aactaaaaat atgatcatag tgagtatgcg
    64441 ttaagaggat agccactaaa ggtttttcaa aggatttaat tttagcaatg atttcttggc
    64501 cgttacttcc tggatcaatg aggataacag cttgatcatt aacgaggtaa taagtatttt
    64561 caccagcaat gtggtttatt gttttataga ttttcataag gatagtgtac caaaaaatca
    64621 agactttgtt aaaaaaagag tagcggaaaa taaatggcaa ttagtttcag aaaatatgag
    64681 atctcacagc aatttcttga caccgttttc ataaaggtgt atcataaaag taatcaataa
    64741 gccaagccta aagctgaact tagtttaaga acactgactt tttgagagca acctaatcgg
    64801 ttgactaaaa aatatgaggt ggaagatatg tcaaaagttg ctattgttac tggtgctggt
    64861 caaggaattg gatttgctat tgcgaaacgt cttcatgcag acggctttaa aataggcatt
    64921 ttagactata atgaagagac tgctcaggct gcggttgata aattatcacc tgaggatgct
    64981 gttgcagttg tagcagatgt ttcaaaacgt gaccaagttt ttgatgcttt ccaaaaagtt
    65041 gtagatactt ttggtgattt gaatgttgtt gttaacaatg ctggtgttgc cccaacaacc
    65101 cctcttgaca cgattactga agagcagttt gaaaaggctt ttgcaatcaa tgtcggagga
    65161 acgatttggg gaagccaagc agctcaaaaa cattttagag aattaggtca tggcggaaaa
    65221 attataaatg caacatcaca agcaggatgt gaagggaatc ctaatttgac tgtttatggt
    65281 ggtacaaaat ttgcagttcg tggtattaca cagactttgg caaaggattt ggcatcagaa
    65341 ggaatcacag tcaatgctta cgcaccaggt attgttaaaa cacctatgat gtttgatatt
    65401 gcccatgaag ttggtaaaaa tgcaggcaaa gatgatgaat ggggtatgga gcaatttgca
    65461 aaagatatca ctttgaaacg cttgtctgaa ccagaagatg ttgctaatgc agtaggcttc
    65521 ctagcgggag atgattcaaa ttatatcact ggacaaacaa tagttgttga tggtggtatg
    65581 gtattccatt aaaaatgatt aatactgaca ctgtgagtga aactcacagt gttttttata
    65641 cttcttaaaa aattatccta tcttggttat tggagtgatg gcacctttga gatatagtca
    65701 tgttttgttt tatagatata gcgtgctata atagacttac tatgacccag aaaaaactta
    65761 gaaaatatgc agtagtggac ttggaagcta ctggagcagg tcccaatgct tctattattc
    65821 aggttgggat tgttattatc caaggaaata aaattattga tagttatgaa acagatgtta
    65881 atcctcatga atctttagat gagcatattg ttcatttgac aggtattacg gataagcagt
    65941 tggctaaagc tccggatttt ggtcaagtgg cgcatcacat ttatcaattg attgaagatt
    66001 gtatttttgt tgcccacaat gtaaagttcg atgcaaattt attggcagaa gctctttttt
    66061 tggaaggata tgagttaaca ataccacgtg ttgatactgt tgaattagcc caactatttt
    66121 tccctcgctt tgaaaagtat aaccttggtc acctatctag gcagctcaat attgatttgg
    66181 cagaagctca tactgctatt gcagatgcaa gagctacagc tatactgttt ctaagacttt
    66241 tacaaaaaat tgagagcctt ccaattgagt gcttagaaag cttattagtc tattcagata
    66301 gcctgctatt tgaaacagca atggtcattc aagaaggatt agccaaagcc aaaccttatg
    66361 atcccaacaa atacattaaa atcagacaga ttctcttacc aaagggctca aaagctctca
    66421 agccttatca aatatcaaaa agcttcccta ttaatatggc actattaggt ctggaagaaa
    66481 ggcctaaaca gactcaattt gctcagttaa ttgacgaaga ttaccatcag ggagtagcta
    66541 gttttattga agctcagaca ggtattggaa aaacctacgg ctacctgcta ccccttttgg
    66601 caaaagaaga tcaaaaccaa atcattgtca gtgtgcccac caaacttctt caagaccaat
    66661 taatggctgg tgaagtagct gctattcaag aacaatttta catcgcctgc catagtttaa
    66721 aagggcccgc caattaccta aagctagata gctttgcaga tagtttggac caaaatgacc
    66781 agaaccgttt ggtgaatcgt tataaaatgc aattattggt ttggctctta gaaactaaga
    66841 caggagacct tgacgaaatc aaacaaaagc agcgctttgc agcttatttt gagcagctta
    66901 agcacgatgg agacattaag cagtcttctg aattttacga ttacgatttt tggagagtta
    66961 gttatgaaaa agccaaaaca gcccgtctcc tgattaccaa ccatgcttat tttttacacc
    67021 gtgttcaaga tgacaaggac tttgctagaa acaaggtctt ggtctttgat gaggcccaaa
    67081 agctgatgct ccaattagat caattatcac gtcatcagct taacctgacg gtttttttac
    67141 aaacaataca ggccaagtta agcaaccctt tacctctttt agaaaaacgc ttattggaaa
    67201 gcttgtcgtt tgaactggga caagtgtcaa gtgattacta tcaaaataaa gagcaccagc
    67261 ttgctcatga ttggtctcgt atagctggct acgccaaaga attaacagga gcagattatc
    67321 aagagttaca agcctttttt gccacctcag atggtgacta ctggcttagt agcgaaaagc
    67381 aagaggagaa gcgagtgact tatctaaaca gtgctagtaa ggcatttatt catttccaac
    67441 agctcttacc agaaacggtg aaaacttatt ttgtttctgc cactttaacc atcagctcag
    67501 aagtaacctt ggcagaccta ttaggttttg aagagtatct ctatcatgtc attgaaaagg
    67561 ataaaaagca agaccagttg gtgcttgttg atcaagaggc gcctatcgtg acagaagtca
    67621 gtgaccaaat ctatgtggaa gcaattgcaa aacgaatcga aagcttgaag caagagggtt
    67681 atcctatttt agtgcttttt aattctaaaa aacacttgct gttggtttca gactatctag
    67741 accaatggca ggtgcctcac ttagcgcagg aaaagaatgg aacagcttac aatattaaaa
    67801 aacggtttga tcaaggagag caaactattt tgcttggttt aggttctttt tgggaaggag
    67861 ttgattttat tcaagcggat cgtatgatta cccttatcgc acgattgcct tttgataacc
    67921 cagaggattt ctttgttaag aaaatgagtc attatctatt ggaaaaaggt aaaaatcctt
    67981 tcagagatta cttcttgcca atgactattt tgcgattaaa acaggctatt ggccgcacga
    68041 tgcgtcgaca agatcaaaag tcagtggtta ttattttgga tcgtcgtctc cttacaaagt
    68101 cctatggaca agttattttg gaaggtctcg gtcaggaatt tttgatttct caacaaaatt
    68161 ttcacgattg tctagtagaa acggactgtt ttctgatata atggaaagga tctattatat
    68221 cagaaaaatt tttaatggcg ttaagcacaa tcaactaaca tttaaattag tttgaacttt
    68281 tattatgctc ttttagacaa ctgttcaaat gttttcaaat tgtttttttg ataaggacaa
    68341 taaatgaaca aatttttggt tttagtaaac ccaattactg ttcttttcat tagtgtcagt
    68401 tgctatcaaa acagcttgtc atagttcgtg cgatcagtag cgagtattgg taaaactgaa
    68461 accgtagatt atgaaaaaat gatctgttga tcattaatta atctgaagat aagaagtcga
    68521 taaaaaggag atacgatgcc caaactatca aagcgagttt tagaaatgaa agagagtgtt
    68581 actctggctg caggtgctag agctaaggct ttgaaagcgc agggccgcga tgtactgaat
    68641 ttaactttag gagaaccaga tttttttaca cctaagcaca ttcaagacaa ggcgattgaa
    68701 tctattcaaa atggtacggc tagcttttat acaaatgctt ctgggcttcc agaattaaaa
    68761 gttgcgattg ccacatacct gaaaaatcag tatgggtatc acttgtctcc tgatcagatt
    68821 gtggcaggaa caggtgccaa gttcatcctt tatgcctttt ttatggctgt tttaaatcct
    68881 ggtgaccaag ttctcattcc aacaccatat tgggtatctt attctgacca agtaaaaatg
    68941 gcagaaggtc agccgatctt cgttcaagga ctagaagaaa atcaattcaa ggtaactgtt
    69001 gaccagctgg aaagagcaag gacaagtaag actaaagttg tccttatcaa ttctccttcc
    69061 aatccaacag gcatgattta tggtgctgag gaattaaggg ccattggaga atgggcggtg
    69121 cacaacgata ttcttattct ggcagatgat atttacgggt ccttagtcta taacggcaat
    69181 cagtttgttc ctatttcaac actctcagaa gcgattcgtc gtcaaaccat tacggtcaat
    69241 ggcgtggcta aaagttatgc catgacaggc tggcgggttg gttttgcagc aggtgaacca
    69301 gagatcattt cggcaatgag taagatcatc gggcagacta cctctaacct gacaaccgtt
    69361 tcacaatatg ctgctatcga ggctttctgt ggtagtcagt catcacttga agagatgcga
    69421 ttagcatttg aagagcgcct taatatcact tatccattgt tgtgtcaggt ccctgggttt
    69481 gaggttgtta aaccacaagg agctttttac ttctttccaa atgttaagaa agccatggaa
    69541 atgacaggtt tttccgatgt gacaagcttt gccaatgcta ttttagagga agtcggatta
    69601 gctgttgtga gtggagcagg ctttggcgca ccggaaaatg ttcgtctgag ttatgctaca
    69661 gatatcgaaa cccttaaaga agctgttcgt agactgcatg tctttatgga aagtaatgaa
    69721 attaattaaa taaaaataga gagaaactta tgtcaaaaaa acttatttca attgttgatg
    69781 ttaaagatta tgttggtcaa gaagttacta ttggtgcttg ggttgctaac aaatcaggta
    69841 aaggtaagat tgcgtttgta cagttgcgcg atggttctgc ttttttccaa ggtgtcgctt
    69901 ttaaaccaaa cttcattgaa aaatatggtg aagaatcagg tcttgaaaaa tttgacgtta
    69961 ttaaacgtct caatcaagaa acatctgttt atgtaacagg gattgttaaa gaggatgagc
    70021 gttctaaatt tggctatgag cttgatatta ctgaccttga aatcattgga gagtcacatg
    70081 aatatcctat aactcctaaa gagcatggga cagacttctt gatggacaac cgtcaccttt
    70141 ggttgcgttc tcgtaaacaa atggctgtta tgcaaattcg taacgctatt atttatgcaa
    70201 cttatgaatt ctttgaccaa aatggtttta tcaaatttga tagcccaatt ttatcagaaa
    70261 atgcagcaga agattcaaca gagttattcg aaacagacta ttttgggaaa ccagcatttc
    70321 ttagccaatc tggtcaatta taccttgaag ctggagcaat ggctctaggc cgagttttcg
    70381 actttggtcc agtctttcgt gctgaaaaat ctaaaacacg tcgccattta acagaatttt
    70441 ggatgatgga tgctgagtat tctttcttgt cacatgagga atcacttgac cttcaagaag
    70501 cttatgttaa agcattgatc caaggcgttc tagatcgtgc gcctcaagca cttgatattt
    70561 tagaacgtga tgttgaggct ctcaaacgtt atatcacaga gccattcaag cgtgtttctt
    70621 atgatgatgc tattacactt cttcaagagc atgaagcaga tgaagataca gattatgaac
    70681 atttagagca tggtgatgac tttggttccc cacatgaaac ttggatttct aattactttg
    70741 gagtaccgac atttgtagtg aattacccag caagctttaa agcattttat atgaaaccag
    70801 ttcctggaaa tccagaacgc gttctttgtg ctgatctttt agctccagaa ggttatggag
    70861 agatcattgg cggctcaatg cgtgaagaca actacgatgc tcttgtgact aaaatggatg
    70921 aactaggtat ggataaatca gaatatgact tttaccttga ccttcgtaaa tatggctctg
    70981 ttcctcatgg cggttttggt ataggtattg aacgtatggt aacttttgtt gctggtacca
    71041 aacatattcg cgaagctatt ccattcccac gtatgttaca tcggattaga ccctaataat
    71101 acaaaaaagt tcatgtcatc tatgaacttt ttgtattggt aagaagtgag tgtgttataa
    71161 aaacatcaat atgtcctaaa ggagagataa gaaatagtag agtttgaacc tacatccttt
    71221 gtgaagataa attttggaag tttagtagat cagttagcag ataagacaat atagccttgc
    71281 tcaagggata ttttatagac aagtatttgg actacgatta tcaaatagac actctcattt
    71341 gatactaaaa aggtctcgtc tattcatata ataggagagc tacgggagtt attattaaaa
    71401 ttagctgatt tttacagttc aaaatgtgtt accacttttt cacttcttag ctttcttatg
    71461 tatgtggtat aatgaaggtg gacggttcga tagagaaagg gaaattgtaa atgtcagaca
    71521 aacacattaa tttagttatt gtgacaggaa tgagcggcgc tggaaaaaca gttgccattc
    71581 agtcttttga ggatctaggc tactttacca ttgataatat gcccccagcc ttggttccaa
    71641 aatttttaga attaattgaa caaaccaatg aaaatcgtag ggtggctttg gttgtcgata
    71701 tgagaagtcg tttgtttttc aaggaaatta attctacctt agatagtatt gaaagcaatc
    71761 ctagcattga ttttcggatt ctttttttgg atgcaacgga tggagaattg gtgtcacgct
    71821 ataaagaaac cagacggagc caccctttgg ctgcggacgg tcgtgtgctt gatggtattc
    71881 gattggaaag agaactccta tctcctttga aaagcatgag ccaacatgtg gtggatacaa
    71941 caaaattgac ccctagacaa ttgcgtaaaa ccatttcaga ccagttttct gaagggtcta
    72001 atcaagcctc tttccgtatt gaagtgatga gctttgggtt caaatatggt cttcctttgg
    72061 atgcggattt ggtttttgat gtgcgttttc tacccaatcc ttattatcag gtagagcttc
    72121 gtgaaaaaac aggactagat gaggacgttt ttaattatgt gatgtctcac ccagaatcag
    72181 aggtgtttta caagcatttg ttaaacctta ttgtccctat cttaccggct taccaaaaag
    72241 aagggaagtc tgtcttgacg gtggctatcg gctgcacagg aggccaacac cgcagcgttg
    72301 cctttgccca ttgcttggca gaaagtctgg caacagattg gtcggttaat gaaagccatc
    72361 gtgatcaaaa tcgtcgtaag gaaacggtga atcgttcatg aaaaatccta aaatgactgt
    72421 tataggtggg ggtactggca tctccattat cctaaaaagc cttcgtaatg aagcagttga
    72481 tattactgct gtggtcactg ttgcagatga tggtggttcc tcaggagaac ttcgtaatgc
    72541 catgcaatta gccccgccag gagacttacg gaatgtcttg ttagcgatga gtgacatgcc
    72601 aaaattttat gagcgggttt tccaataccg ttttaacgag aatgatggag ccttggctgg
    72661 tcaccctcta ggcaatctca ttattgctgg tatctctgaa atgcaaggct caacctacaa
    72721 tgccattcaa attttaacca aatttttcca tattacaggt aaaatttacc cctctagcga
    72781 gcaggccttg acccttcatg ctgtttttaa agatgggcat gaagtagcag gagaaagttc
    72841 tattgccaaa taccaaggca tgattgacca tgtctatgtg accaacacct acaacgacca
    72901 aaagcctcag gccagtcgta aggtggttga ggctattcta gaaagtgaca tgattgtctt
    72961 gggaccaggc tcactgttta cctctatttt acctaatttg gtcattccag aaattaaaga
    73021 agctttgcgc cagactaaag cagaagtggt gtatatttgt aatatcatga cccagtatgg
    73081 tgaaacagaa caattttcag atgcagacca tgtggctgtt ttaaatcagc acttaggaag
    73141 agatttgatt gatacggttt tggtaaatgt ggctaaggtg ccgcaggctt acatgaattc
    73201 taacaaattt gatgaatacc tcgttcaggt tgatcacgac tttgctggcc tttgcagggc
    73261 tgctaagcgt gtgatttcgt cttatttttt acggttggag aatggcggag cttttcacga
    73321 tggcaactta gtggtggaag aattaatgaa tttagtgagg atagtcaagc aatgagtttt
    73381 acaaccaagg tcaaagagga attaattcac ttgtccacag gtgacaacaa tgaattggcc
    73441 gccatcatca aattatcagg cagcttgggc ttagctcacc aaagccttca tttatccatt
    73501 accactgaaa atgctaaaat tgcccgctac atttattctt ttattgaaga tgcctatgtt
    73561 atcgtgccag aaatcaggta tcatcaaaag acgaacctgc gcaaaaaccg tgtttacacc
    73621 gtctatgttg agcaaggtgt ggaaaccatt ttagccgatt tgaaattagc ggactccttt
    73681 tttggtctgg aaacaggcat cgaacctcag gttttatcag acgataatgc tggccgttct
    73741 tatcttaaag gggcttttct agcggcaggt agcatcagag atcctgagtc aggcaagtat
    73801 cagttagaaa tctattcagt ttatcttgat catgctcaag atttagctca actcatgcaa
    73861 aaatttatgc tagatgccaa aaccattgag cataaaagcg gtgcagttac ttatttgcaa
    73921 aaggcagaag atatcatgga ctttttaatt ataattggtg ccatgtcctg caaagaagac
    73981 tttgaagcca tcaaattact tcgagaagct cgaaatgata ttaaccgtgc caataatgca
    74041 gaaacagcta atattgccaa aactatcagt gctagcatga aaaccattaa taatattatt
    74101 aaaatcatgg acacaattgg tttagaaagt ttaccgattg aattgcaaca ggtagcccag
    74161 cttcgggtta agcatccaga ctattccatt caacaagttg ctgatgccct tgagttccca
    74221 atcaccaaga gcggggtcaa ccatcgcttg cgtaaaatca ataaaattgc agatgactta
    74281 tagaacattt ttatcgtatg agcctttgtt catacgattt ttctgtctaa aagtcgtttt
    74341 ccattgtttt tttgaagtgt ctgatgttct gtgatatgat aaaagggata ataacgtttg
    74401 taaaggagac cgataatggc atgtacaact atactcgtcg gtaaaaaggc atcttatgat
    74461 ggctcaacca tggttgctcg aacagaagat tctcaaaatg gtgatttcac gcctaaaaaa
    74521 atgattgtgg tgaaaccaga agatcaaccg agacattacc gttcggtgca atcttccttt
    74581 gaaatggact taccggacaa tcccatgact tacacgtctg ttcccgatgc gcttggtaaa
    74641 gatggtatct gggcagaagc aggcgtgaac gaggctaatg tggccatgtc agcaactgaa
    74701 accatcacta ccaattctcg tgttttaggg gcagatcctc tagtagcttc tggtattggt
    74761 gaggaggaca tggtgacctt agtgctccct tatatccgtt ctgcgcgtga aggggttttg
    74821 cgccttggtg ccattttaga agactatggc acttacgagt caaatggtgt ggctttttca
    74881 gatgaacatg acatttggtg gctggaaacg attggtggtc atcactggat tgcaagacgg
    74941 gtgccagatg atgcttatgt caccaatccc aatcaatttg gcattgatca ttttgaattt
    75001 aacaatcctg aagattacct ttgctcagct gatttaaagg actttattga cacgtatcac
    75061 ttagatttaa cctatagcca tgagcatttt aatccgcgct atgcttttgg tagtcaacgt
    75121 gacaaagacc gtcactataa tacgccacgt gcttggatca tgcaaaaatt cttaaaccca
    75181 gaaattgtgc aagacccgcg cagctttgcc cttgcttggt gtcaaaaacc ttaccgtaaa
    75241 ataacagtag aagatgtcaa atatgtattg agtagtcact atcaggacac ggtttatgac
    75301 ccttacggtt cagaaggaac tcctgttagt aagaaaatct ttcgccctat tggcattaac
    75361 cgtaccagcc aaaccgctat cttacatatt cgtcctaata aacctcaaga aattgcggct
    75421 atccagtgga tggcttatgg gtcaatgcct tttaatacca tggtgccttt tttcacacag
    75481 gtgaagacta ttccagatta ttttgccaac acttacgaaa atgtgtctac cgacaatttc
    75541 tattggacca accgtctgat tgcggctttg gcagatcctc actacaatca tcatgaaact
    75601 gatttggaca attacttgga agaaaccatg gcaaaaggtc atgccatgtt acatgctgtg
    75661 gaagcacagt tattggctgg tgaaacagtc gatttggaag aggaaaatca aaagatgagt
    75721 gactatgtgc aaggagaaac gcagacgctg ttgaacaaga ttctctttga cgctagcaat
    75781 ctaatgacca atcgtttcag tttgagcgat taatagtgaa gctaaggctg agcaactgct
    75841 tagccttttt tacgataact ttttaggaaa agtaatcgca aaaagacaaa aacttggaaa
    75901 aaaaatcaaa gtatgctata cttaactggt caatttttaa ccagttaata acaaaggagg
    75961 aatcatgaaa aagaaaattc ttttaatgat gagtttaatc agtgtctttt ttgcttggca
    76021 acttactcag gcaaaacaag tcttagcaga gggtaaagtg aaggtggtga caactttcta
    76081 tcctgtttat gaatttacaa aagggattgt tggtaatgat ggcgatgttt ccatgcttat
    76141 gaaagcagga acggaacctc atgattttga gccttctaca aaagacatta aaaaaatcca
    76201 agatgcagat gcatttgttt atatggatga caatatggaa acttgggttt ctgatgtgaa
    76261 aaaatcattg acatctaaaa aagtgaccat cgtcaaggga actggtaaca tgctcttggt
    76321 agcaggagct ggacatgacc atcaccatga ggaagctgac aaaaagcatg agcataataa
    76381 acatagcgaa gaaggacaca accatgcttt tgacccacac gtgtggttgt caccataccg
    76441 tagcattacg gtcgttgaaa atattcgcga cagtctttca aaagcttacc cagaaaaagc
    76501 agagagcttc aaagccaatg ccgctactta tattgaaaaa ttaaaagagc ttgacaaaga
    76561 ctatacggca gcactttcag atgctaagca aaagagcttt gtgacacaac acgcagcttt
    76621 tggttatatg gcacttgact atggcttgaa ccaaatttct attaatggtg tcacaccaga
    76681 tgcagaacca tcagcaaaac gtattgctac tttgtcaaaa tatgttaaaa aatatggtat
    76741 caaatacatt tattttgagg aaaatgcgtc aagtaaagtc gcaaaaaccc tagctaaaga
    76801 agcaggagtt aaagcggctg tgcttagtcc gcttgaaggt ttgactgaaa aagagatgaa
    76861 agctggccaa gattacttta cggtcatgcg taaaaacctt gaaaccttac gcttaaccac
    76921 tgatgtggct ggtaaagaaa ttcttccaga aaaagacacg actaagacag tttacaatgg
    76981 ttatttcaaa gacaaagaag tcaaagatcg tcaattatct gactggtcag gtagctggca
    77041 atctgtttac ccctatctac aagatggtac tttagaccaa gtttgggact ataaggctaa
    77101 aaaatctaaa ggtaaaatga cagcagccga gtacaaagat tactacacta ctggttataa
    77161 aactgacgtg gaacaaatca aaatcaatgg taagaaaaag accatgacct ttgttcgtaa
    77221 tggtgaaaag aaaaccttca cttacacata cgccggcaaa gaaatcttga cctatccaaa
    77281 aggaaatcgc ggagttcgtt tcatgtttga agctaaagaa ccaaatgctg gcgaattcaa
    77341 atacgttcaa ttcagtgacc atgccattgc tcctgaaaaa gcagagcatt tccacctgta
    77401 ctggggtggt gacagccaag aaaaattaca taaagagtta gaacattggc caacttacta
    77461 cggttcagac ttatctggtc gtgaaattgc ccaagaaatc aatgctcatt aatcttaact
    77521 cactaagcaa atcttctttt aagtaaggag gtttgctttt tctttgtgga gtaaaaaaat
    77581 caataattct caacattaat ttgacggaca cttatgatta taatatactt taagtggtta
    77641 taacaagtta gaggtgaata agatgccaaa agaacaacca ctctatctac agattgttga
    77701 tgacttggaa gtgaaaatca aaaaaagcat gatagaaaac gataagttgt tgtcagaacg
    77761 agaattaagt gacctttacg gtgttagtcg tatcacgatt agactggctc ttaaggaatt
    77821 ggaattacga gacttaattt ataaaaagca gggcaagggg acttatgttt caggaatcaa
    77881 agaacctgtc actgatttat caagtactta cagctttaca gagcaaatga aaaaagtggg
    77941 gaaaactcct aaaacagaga ttctttcttt tgaacagtat caggtaacac cttacttgtc
    78001 tggtctctta gagtttgatc ccgatacaga agtttttgaa ttagaacgcc taaggattgc
    78061 agatgatatg cccttgatgt ttgaacgatc ctatattcct gctcagcttt ttcaagggtt
    78121 aagcattgag cacttgaagc gtaagccaat gtacgattta tttgcagagg attaccaaga
    78181 aactattcgc ctagcagaag aagagtttta tgctagcatt gccttggact atgaagcagg
    78241 tctcttaggc attaaaaagg gagatcctgt cttacatatt attcgtaaaa cttataatga
    78301 taacaatatc ttaattgaat tgactttcag cattgcaagg gcggatcagt ttaggtaccg
    78361 agtacaacat caccctaatg gttaaggaat tggaggttag gacatgttta caaaaacgca
    78421 ggaagctttg gaggctcttg gtgcagctat cactaccaag gaaattaaac aagaaccccg
    78481 tttatggcaa gaaaccatga cgttttttga agaaacaaga gattctctgg attctttttt
    78541 aaagagagtt tgtaacagcg ctaacagaaa taacgttcat gtcatcttta caggtgcggg
    78601 tacatctgag tacatcggta ataccatttg cccttacttg aagaaggtgg ggaatcggca
    78661 gcgctatctc tttgagagcg ttgcttcaac cgatttggtt gcggcgccag attattatct
    78721 tgttgaggaa gagacggtac tattagtctc ctttgctagg agtggtaata gtccagaaag
    78781 tgtagcggct gttaacctgg tcaatcaact agtgccaaat agttatcatt taaccattac
    78841 ctgcgccaaa gatggagaac tggcgaaaaa agcacagcaa gatgagcgtt cttaccttta
    78901 tttgatgcct gaagacgcta atgatgctgg ttttgccatg actggtagtt ttacctgtat
    78961 gatgctagcg gctcttttga tttttgatga tgctaacagt atagctcaga aagaagctta
    79021 tgtgactgat atgattcttg ctgggcaagc tgttattgac caagaaagac ggctacaaga
    79081 gctagctgat ttaggatttg aacgtttagt ttatctaggt tctgctggtt tagccaagtt
    79141 aacccaagaa gctcaattaa aaatgttaga attgacagct ggacaagttg cgaccctcta
    79201 cgagtcctct atgggcttta ggcatggtcc gaaatctttt attaatgacc gtaccttagt
    79261 cattggattt gtcaataatg atgcttacgt cagacagtac gatttggaca tgttagagga
    79321 aatccaagca gatggcattg cccttaaaat cttggctcta ttgcaaggag gggatatcaa
    79381 cttttcagag gaccaatttc gactagacac ccgtcactta ttgccagaag cttacttagc
    79441 ttttcccatg attttagtcg cgcagacctt ggccctctta acggccgtta cattaggaaa
    79501 ttcccctgac accccatctg cgacaggaac ggttaatcgt gtggtcaaag gagtaacgat
    79561 tcacccttac ccgactagta gtcgtcaatg caacaaagct taaagctttt gtgctagtag
    79621 gccaaaagaa aaaccctcct gatacaggaa ggttttttgt attgtcttgc ttattttgct
    79681 gcgtttgcgt ctttgagacc gtattttttg ttgaagcggt ccacacgtcc atctgcttga
    79741 gtgaactttt gacgtcctgt gtagaatggg tgtgaatctg atgaaatttc cacacggata
    79801 agtgggtaag tttcaccttc aaactcaaca gtttctttag aagcttttgt tgagccgcta
    79861 aggaactggt aacctgtagt tgtatcaagg aaaacaactg gacgataatc tggatgaatg
    79921 tcttttctca tcttaaaaaa ttcctttctg ccatgacact tgatgcatca tagttattaa
    79981 ctattctagt gtaacaaaac ttgaatgact tgacaaggct tttctttcct tattttttaa
    80041 aaatcctaaa tctcttggca aacagcgatg agttctcgga aaatagcttg attttcttct
    80101 aaattagctg agttggctcc gctagcaagg ggatgccccc ctccaccgtg acgcttagca
    80161 atgccattaa taatcttttc tttactgcgc atacgcacac ggtagttgcc gtcagttaac
    80221 tcaacaaaaa tagcccaagc ttgaacgtta tcaattttac caggagcaca gacaatagca
    80281 gagctttctg ctagggtcac gtcaaaatgt tttaaggttt cttggctgac aaggacataa
    80341 gcagccccac tctcatcaat tgttaaatgc tcaaagacgt agctttgcag ctttgctatt
    80401 ttcaaaggaa acgaatccat ttgccttgaa atcgcagcaa agtcgaactc gaaatgtctg
    80461 agttggctag caatggaaag ggttttacta gtggttgagg cataaagaaa tcgccctgta
    80521 tcaccaacga taccagtgta taagagctta gcagctttgt cagagagagt aagattctga
    80581 ctaaaggcaa agtctgcaat gatttcactt gcgctagaag cgcttgtgtc cacataatag
    80641 aagtcaccat acacatcatc gttgggatgg tgatcaatct taattaagca ctgccccagt
    80701 gtgtagcgct catcatcaat ccttggtcga ttcgctgtat ctgtaatgat gaccaaagcc
    80761 tctttgtagt ctttgtcagt cacctgatcc atttggctca tccaagctaa actaggctca
    80821 tcaaaaccag tcattaaaac ctttttgtct gggaaatttt gtgcaataat ttctttcaag
    80881 ccggcctgac taccaagagc atcagggtca ggattttgat ggcgatggat aataatagtt
    80941 tggtgagctt ttattttatc taaaattgtt tcaaaagttg ttatcatgct ttaatctttc
    81001 tttttcaaaa agaggaaaat aaccgtttaa catagtcttc aaaaaacggt ttgtgtcata
    81061 aggaggtgtg cgttatgttc agtggctaat gctagaattt tttaagattg tcaaagacca
    81121 taaattgaca ttttatctga aaatcatatc ctattttatt atagcataaa agtaagctct
    81181 agataatggt aaattaatct aggaagaaaa gaggttagtt atcagctatg atactatcaa
    81241 agctagtctt gcaaatgcaa gtgaaaaaat agtttttaag tgttttaagt aatcatatca
    81301 accttctcgt taaagaatta gtgcttttcc taaaaaagtg tgctaaaata aacatagttt
    81361 agtaattttg ggaggaattt atggcattag caaaaatcgt ttatgccagc atgacgggaa
    81421 atactgaaga aatcgctgat atcgttgcaa ataaattgca agaattgggc catgatgttg
    81481 acattgatga gtgcacaaca gttgacgctt cagagtttga gaatgctgat atcgctgtcg
    81541 ttgcgactta tacttatggt gatggtgact taccagatga aatcgttgat ttttacgaag
    81601 atttacaaga tttagattta gaaggtaaaa tctatggcgt tgtcggctct ggtgacactt
    81661 tttatgacta tttttgcaaa tctgttgatg acttttcaga gcaatttgcg cttactggtg
    81721 ccatcaaagg tgcagagcca gtcaaagtag atttggcagc agaagatgaa gacatcgatc
    81781 gtttagaggc ctttgcagag caactctcac aggctgttaa taatctataa aactataact
    81841 ctcacaggct gttaataatc tataaaacta tttagtaaaa atgtcagggg cttccttggc
    81901 atttttagct ttttaaccta aaataaaggg aatgtcactt cagggtagga attgaaaaaa
    81961 caatcagctt caccttgctt ctgatcctct tattaactat aataaaaaga taatctaata
    82021 catctagaaa aggaaagtta tgcgtttaga agagatacga caagaaatca atagtattga
    82081 tcaccacttg gttgccttat tagaaaagcg gatggcactt gtagagcaag taacagctta
    82141 taaactagcc aatcacttgc ctgtcttaga tcaggtgcgg gaaaatcaga tcctagatag
    82201 ggtttcttat ctcgttaaag accaagcatt tgagccagct atccatgaga cgtttaaaac
    82261 cattatgtct ctttcacgga agtatcaaac gcaacgctta acaggtggtg acactaatga
    82321 ttaaatcaat tgcaacactg cctaaaccct ccttaaaaga agcgttagga ctaataggct
    82381 tggcgcttcc cataggggtc gcggttggag tggttgatgt gatttttggt aaagggcttt
    82441 tgtttctttc cgaatatcgc gatcaccacc ttttcttgct tcttcctttt cttgccctag
    82501 caggtcttgt tatcgttttt ctttatgata agttaggcaa agaggttcgt caagggatgg
    82561 gattggtttt tcaggtaggg catggtcaaa aagatcagat tcctcctatt ctcattcctc
    82621 ttattttgtt ctcgacttgg gtaacccact tatttggagc gagtgcgggt cgagaagggg
    82681 tagccgttca aataggagct accatctctc attattgtca gagatttgtg actagtcaag
    82741 aagccgcacg acaccttttg attatgggga tggcagcagg ttttgcagga ctttttcaaa
    82801 cgccgattgc tgctgtcgta tttgcccttg aggttttgtt ggtaggaacg cttcgctact
    82861 gcgctttatt gccttcctta gttgctgctt gcgtggcttc ttggacctct cattctttgg
    82921 gattagagaa atttacgatt gttcttgaag aaacattgac cataactccc ttaaccttag
    82981 ttaaattaat tgggttaggt cttatttttg gtctggtggg aaatagtttt gcctgtttac
    83041 ttggctggtt taaaccttac ctgagtcaaa agctaccaaa tccttatctc cggattgctt
    83101 tcattggtgt tttgttatct atctgtttga tgattggtca cgttggaaga tatagtggtc
    83161 tagggactca tttgattgcg gcagcttttt ctggccaaac tatcctaact tacgactggc
    83221 ttttaaaaat gatcgtgacg gtgattagct tatctgcagg ctttcaaggt ggtgaagtga
    83281 cgcctctatt tgctattgga gcttctttag gcatcgtttt ggccccttac ttaggtcttc
    83341 ctgtactgtt ggttgctgca cttggttatg tcacggtatt cggaagtgca acaaatacct
    83401 tttgggcccc tatctttatt ggggtagagg tctttggtcc agagaatgcc ctagcatatt
    83461 ttgtcacctc ggctgcagcc tatatggtta gtcacagaca ttccatttac agttatcaaa
    83521 aagtagtcat gatcaattta aaagacatga cggtaaatca gatggattta aaaaaatagc
    83581 tttacaataa agaagctttt tgttagaata aatctcgtgt gtaatggaca cacgaaaatt
    83641 acggctaatc cgctaagaca agtacttaag attagtaaga taggagaata aaaatgaatc
    83701 cattaatcca aagtttgaca gaaggtcaac ttcgctctga tatccctaac ttccgtcctg
    83761 gtgacactgt tcgcgttcac gcaaaagttg tcgaaggaac tcgcgaacgt atccagatct
    83821 ttgaaggtgt tgttatttca cgtaaaggtc aagggatctc agaaatgtac actgttcgta
    83881 aaatctcagg tggtatcggg gtagagcgta cattcccaat ccacacacca cgtgttgaca
    83941 aaatcgaagt tatccgccac ggtaaagtcc gtcgtgcgaa actttactac ttgcgtgcat
    84001 tacaaggtaa agctgctcgt atcaaagaaa ttcgtcgtta gtttgaaccg aaacgtaacg
    84061 taatagaata aaaagactag agtctctagt ctttttatgt cgtcgtgaca atgtgataat
    84121 tggtgattaa cgctatgctc gtaggacact ttgaaagttc cttagcagtt ataattagta
    84181 tattgtaata acaaaatgaa gcaaaataaa ctttcagtta tctgatattt catcttgcat
    84241 taccttattt tctaggttaa aatagaagac aaggtgaata taatatagac cccttagttc
    84301 aatggatata acaactccct cctaaggagt agttgctggt tcgattccgg caggggtcat
    84361 tattgtcact gaaaaagcct ttacatcaaa ggcttttttc tattactcaa ttaatgttag
    84421 gagcacaaaa gaggcagttc gattattaac caattcctcc ctatttacag ttgtatggct
    84481 ataaattgac aatcttaagt tagggtctga gtgactaaac ctgtccctaa acgcttttgg
    84541 tggtaattct ttttcagcta aaagcgaaat gtgcgagtgt ttgaataagt gagtatggta
    84601 atcaccataa atttttaggc gcttattgat gtgtgcattt aaaattggta aaccttttga
    84661 atatggaaag ctgttagcac tctgcttgtg attaatctat cgtatgttaa aagtgacatt
    84721 taaattaaat cattttttat acatatattt caacaggtat ttcaacagga tttatcatat
    84781 tggaaaatag cggtgattct attggtattt tactattgac aggaatttcc ctgccttttg
    84841 tctcctaaag aagatcagct ttgatttcta acttgattag agtgggcttg gtactgttta
    84901 tgaattatca gtacatactt tctggagatc aaaaaggaaa ggaacagcta aagaggtgta
    84961 tgtgttacta ttagaggaat agaacatcgc aagactcgtt tattcagtca ttacgatacc
    85021 tgttttattt aggaaataac tataatatta agtgaatttg tgatataatg aaaggtatga
    85081 attatcaaga ttatatatgg gatttgggag gtaccttact cgataattac gagctttcaa
    85141 cccaagcttt tgtccaaacg ctagcttttt tcagccttcc aggagatcac gatgctgttt
    85201 accaaaaatt aaaagaatca accgctatcg ctgtggcaac gtttgctcct aatgagctag
    85261 aatttttgca tgtgtatagg ctaaaagaag cagacaaatt ggcacaaccc atttggtgtt
    85321 tgggagctaa agaaattttg gaaaagatag cgacttcagg ttcgcgaaat tttttaattt
    85381 ctcatcgaga ttgtcaggtg aaccaacttt tagagcaagc tgggttgcta atctatttta
    85441 cagaagtcgt gacagcttca aatggctttg ctcggaaacc aaatcctgaa agtttgtttt
    85501 atttaaaaga aaagtatgat attgatagtg gattagtaat tggagatcgg ctaattgata
    85561 aacaagcagg acaagcagcg ggttttaata ccttgcttgt tgacggtaga aaaaacctat
    85621 tggagatagt aacgtagatg attgaagaaa ataaacattt tgaaaaaaaa atgcaagaat
    85681 acgatgccag tcaaattcag gttctagaag ggctggaggc tgtccgcatg cgtccaggga
    85741 tgtatattgg ctcgacagct aaagagggtt tgcatcattt agtctgggaa attgttgaca
    85801 actcaattga cgaagcatta gcaggttttg cctctcatat taaagtcttt attgaagcag
    85861 ataattccat tacagtagta gatgatggcc gtggaattcc agttgatatc caagccaaga
    85921 caggacgtcc cgccgttgaa acagttttta cagtcttaca cgcaggtggt aaatttggtg
    85981 gaggcggcta taaggtttct ggaggattac atggtgtagg gtcatctgtt gttaatgctt
    86041 tatcaacaca attagatgta cgtgtttata aaaacggcca aattcattac caagaattta
    86101 aacgcggggc tgttgtagca gatcttgagg tcattggaac cactgatgtg actggaacaa
    86161 cggtacactt tacacccgat ccagaaattt ttaccgaaac gactcagttt gattacagtg
    86221 ttttagcaaa acgtattcaa gagttagcct ttttaaaccg tggtttaaaa atttccatta
    86281 cagataagcg ctcagggatg gaacaagaag aacatttcca ttatgaaggt ggaattggtt
    86341 cttatgttga atttttaaat gataaaaaag atgttatctt tgaaacgccc atctatacag
    86401 atggtgaatt agaaggtatt gcagttgaag tagccatgca atacacgact agctatcaag
    86461 aaacagtcat gagttttgct aataatattc atactcatga aggtggaacg catgaacaag
    86521 gctttagagc ggctcttact cgggtcatca atgactacgc taagaaaaat aaaattctta
    86581 aagaaaatga ggacaatttg acaggagaag atgttcgtga aggtttgacg gcggtaattt
    86641 ctgttaagca tccaaatcct caatttgaag gtcaaaccaa aacaaaattg ggcaactcag
    86701 aagtggttaa gatcactaat cgtctcttta gtgaggcctt tcaacgtttt cttttggaaa
    86761 acccacaagt tgctcgtaag attgtggaaa aagggatttt ggcttctaaa gctagaattg
    86821 cagctaagcg agcccgcgaa gtcacccgca aaaaatcagg cttagaaatt tcaaacttac
    86881 ctggaaaatt agcagactgt tcgtcaaatg atgctaacca aaacgaactt ttcatcgtcg
    86941 aaggagattc agcgggtggg tcggccaaat caggtcgtaa ccgagagttt caagctatct
    87001 tgcctattcg cggtaaaatt ttgaacgtgg aaaaagcaac tatggataag attcttgcca
    87061 acgaagaaat tagaagtctc tttaccgcta tgggtacagg ttttggtgca gattttgacg
    87121 tgtcaaaagc tcgctaccaa aagctggtta tcatgaccga tgccgatgtg gatggcgctc
    87181 atattagaac cttactttta accttgattt accgctttat gagacctgtt ctagaagctg
    87241 gctatgttta catcgcccag ccacctattt atggtgttaa ggtcggtagt gagattaaag
    87301 agtatattca gccaggtatt gatcaagaag accaattaaa aacagctctt gaaaaatata
    87361 gtattggtcg ttcaaaacca actgttcaac gttataaagg tcttggggaa atggatgacc
    87421 atcaactttg ggaaactact atggatcctg aaaatcgttt gatggcgcgt gtgacagttg
    87481 atgatgccgc agaagcagat aaagtatttg atatgttaat gggagatcgt gttgaaccaa
    87541 gacgtgattt cattgaggaa aatgcggttt atagtacact ggatatttag tcaccttttt
    87601 agtttcacaa ggaatctgct accaaagagg acgaattgac taaaaatcat gatgcatgat
    87661 gccaacagct ttgttagtta gtacgtcttc atcttgaggg acagcgttaa tgcataggta
    87721 ttgagaccgc cccttaatac ctatgttagt ccttattaag aaagcctttt gagtcgctgg
    87781 tacgagattg ttgaattagt caaatatatt ttgaaatgca ttttaaagta tgttataatc
    87841 gtaatgttat agtgtatttt aaataaaatt ttaataaaag gcgattgagg aatttcagtt
    87901 tttagttatt actggaacaa tgttgataaa tcgtgtctaa ataataagga gattcagatg
    87961 tcaagcggaa ttatcttgct gattgtggct atagtcctac tagtgattat cgcctatcta
    88021 gtgggtgtca tcatacgaaa gcgtaatgat tccctaatta ccagtctaga agaacgaaaa
    88081 caggccttgt ttgctttgcc tgttaatgat gaaattgaag aagtaaagtc acttcatttg
    88141 ataggacaga gccaaacctc ttttcgggaa tggaatcaga aatgggtaga cttaactgta
    88201 aattcgtttg cagatattga aaatcatatt tttgaagctg aaaatttgaa tgatacgttt
    88261 aattttattc gcgccaagca tgagattaat agcgttgaaa gtcagcttaa tcttgttgaa
    88321 gaagatatcg cttctattcg tgaagcactt aatatcttaa aagagcaaga agaaaaaaat
    88381 agtgctcgtg tcacccatgc tcttgattta tatgaaaagc tccaagcttc tatttctgag
    88441 aatgaagata attttggttc aactatgcct gaaattgaca aacagatgaa aaacattgaa
    88501 actgaatttt cacagtttgt cgcactcaac tcatcaggtg atcctgtaga agcttctgaa
    88561 gttctggata gagcagaaga gcatactatt gctctagggc agattacaga gcagattcca
    88621 gctattgtgg ccaagttgga agatgatttt ccagatcagt tagatgattt ggaaacagga
    88681 tatcgccgtt tacttgaaga aaactatcat tttccagaaa aaaacattga ggcacgtttt
    88741 caggagattc gtgagtctat tcgtgccaat tcatcagagt tagttacact tgacttggat
    88801 cgtgctagag aagaaaacac gcatattcaa gaacgcattg attctcttta tgaagtcttt
    88861 gagcgcgaaa ttgccgctta taaggtagct gctaaaaata gtaagatgct acctcgttac
    88921 ctagcacatg tgaaacgtaa taatgaacaa ctcaaagatg aaattgcacg tttatcacgt
    88981 aaatatattc taagtgaaac ggaaagtctg actgttaagg catttgagaa ggatattaaa
    89041 gagatcgaag acagtacact tgctgttgca gaacaatttg gtttacaaga aaaaccattt
    89101 tcagaactgc aagtgacttt tgaacgcagc ataaagacgc ttactaatgt cgagtcaggt
    89161 caaatggatg tttttgcagc agttaaagat attgaaaaaa ttgaatcaca ggcacgccat
    89221 aaccttgatg tttatgttac tcagcttcat atgattaaac gttatatgga aaaacgtcac
    89281 ttgcctggaa ttccacaaga ctttcttagt gctttcttta caacgagttc acagttggaa
    89341 gctttgatgg atgagcttag tagaggacgg atcaatattg aggcagtgtc acgtttgtcg
    89401 gaagttgcga cggttgctat tgctaatcta gaagatttaa cctatcaagt ggttcaaaat
    89461 gctaccttga ctgaacaatt actacaatat tctaatcgct atcgttcttt tgaagcagga
    89521 gttcaaagta gttttgaaca tgctttgaga cttttcgaag tagaaaatga ttatcaggct
    89581 tcttttgatg aaatttctta tgctcttgaa acagttgaac ctggggtaac agatcggttt
    89641 gttaactctt atgaaaaaac acgagagcac attcgttttt gatacttgaa agtcgtgata
    89701 ttctcacgac tttttatcag ctttttggac caatacgtgt ttttgactag aatcttcttt
    89761 ttaatgatca aaagaagaag tagtaacagt gtttttgcta ttgagaggat agttattttt
    89821 tcaaaaatct tttccaaaag gatttggttt tttcaggagt ttgtttgcta agttgatcgt
    89881 tttttgtctg ctttaagatg acttctaaac gtgtttcctt tagatttatt gcgtggtcgg
    89941 tatgaaggat aaacgcaaaa ggtgaagtca tatgcgtttc tgtaataata gtaacaggta
    90001 aatggttttc ttttgctaat ttcatataga gtatttgaag ttgaggtgcc agcttggaag
    90061 agatttttaa gtgtaaaggt tgatagacta actgaaggct cggtaattct cttttcaaat
    90121 agtcttttac tgttttagtt tgagcttcgt ctaataaagc acttaaaacg actcgttcag
    90181 catacgttcc tagatagtag cgttgctgct caggatttaa tcttctttct ccccaggctc
    90241 cttttaatag cttatcttct aaattagtca tagataccct cgcttcttta taatagtttc
    90301 tttattatat cgatttctac aataaaatac caatttgaaa attttcggta aatgtgttaa
    90361 aaaacaagaa agaaagtgat ttttcttgca aaaaacaaag gaagcttttc atgagattgc
    90421 tttttaagtt gattaaaggc ctagtttgtg gtattatgaa catgtaaaat attaaaactc
    90481 ataaggagag tattacaatg tcaattatta ctgatgtata cgctcgcgaa gtccttgact
    90541 cacgcggtaa cccaacactt gaagtagaag tttatacaga atcaggtgca ttcggacgtg
    90601 gtatggttcc ttcaggagct tcaactggtg aacatgaagc cgttgaactt cgtgatggtg
    90661 acaaatctcg ttaccttggt ctaggtactc aaaaagcagt tgataacgtt aataacatta
    90721 tcgctgaggc aatcatcggt tacgatgttc gcgatcaaca agctatcgac cgtgcaatga
    90781 tcgctcttga cggtactcct aacaaaggta aacttggtgc taatgctatt cttggtgttt
    90841 ctatcgctgt tgctcgtgca gctgctgact atcttgaagt gccactttac acttaccttg
    90901 gcggattcaa cactaaagtt cttccaactc ctatgatgaa catcatcaac ggtggatcac
    90961 actcagatgc cccaattgca ttccaagagt tcatgatcat gccagttggt gcacctactt
    91021 tcaaagaagg tcttcgttgg ggtgctgaag ttttccacgc tcttaagaaa attcttaaag
    91081 aacgcggact tgttacagct gtaggtgacg aaggtggatt tgctcctaaa tttgaaggaa
    91141 ctgaagacgg tgtagaaact atccttaaag ctattgaagc agctggttac gaagctggtg
    91201 aaaacggcat tatgatcggt tttgactgtg catcatcaga attctacgac aaagaacgta
    91261 aagtttacga ctacactaaa tttgaaggtg aaggcgctgc tgttcgtaca tctgcagaac
    91321 aagttgatta ccttgaagag ttggttaaca aatacccaat tattactatc gaagatggta
    91381 tggatgaaaa cgactgggat ggttggaaag ttcttactga acgcctaggc aaacgtgttc
    91441 aattggttgg tgacgacttc ttcgttacaa acactgaata ccttgctcgt ggtatcaaag
    91501 aaaatgcagc taactcaatc cttatcaaag ttaaccaaat cggtactttg actgaaacgt
    91561 ttgaagctat cgaaatggct aaagaagctg gatatactgc cgttgtatca caccgttcag
    91621 gtgaaactga agattcaaca atcgctgaca tcgcagttgc aacaaacgct ggccaaatca
    91681 aaacaggttc attgtcacgt acagaccgta ttgctaaata caaccaatta cttcgtatcg
    91741 aagatcaact tggtgaagtt gctcaataca aaggtatcaa atcattctat aacttaaaaa
    91801 aatagacggt aagacagaaa tcggtcattc gtagaatgcg atttcgtcgt cgcacctccg
    91861 tcaggctgac taggttggtc acgacaaaag gagtgaacat ccagtcagct acgacgcaaa
    91921 agttaaagat taaagaatag aaagcttggg aaaatcccaa gctttttgct ttctaaatag
    91981 taaaaattta ctgtgggcta atttatcctg agctaatgta ttagcgaggt aaagttattg
    92041 aggaaggctt ggatttgtac tgcctccaaa aagttggaca ctatatttta aatacagaac
    92101 taagtccttt tataccaatt gtcaagcaca tcaaggtttt aactgaaaaa atgttttaga
    92161 caatagccta ggtttagctg ttgtcttact tgttgtgctc tgattagcat aaaaaagtgt
    92221 acaagaaaaa aaccttgcct aatattttta agatcaaggt gttacaatga tagagcaaca
    92281 acgactttaa tgattttggg tcgaagcgta attgtaaagt ttgttatgca ttatgaggta
    92341 aagcattatc ctgacaaggc aatgtctaga ggcaatcgta tgtggcttgg ttgaagctgt
    92401 ttgcgattgc ctttttcgtt tctcatagaa gtctgcgata tgacaaggat tggtatgact
    92461 agcagaagca atgtcatgga tacacttgaa aagaatcttt ggagcataag gattcccacg
    92521 tttggtaatg tgctcttgag ctagatagtt gccagactca taatgtctaa agtcaatccc
    92581 aatgaaagca ttaatttgat tagcagattg aaagcgacga atagcaccga gtttgccaat
    92641 aatacttgtt gcagttgttt ctgcgatact tggaatagag cgtagaatct tgtcttctgg
    92701 taaaggttga gccaacgcca ccatcttatc aaaaatagct tgacgacgtt cagaaagtct
    92761 aagtaattct ttggcatagt agcgaacctc ttctatcatc ggagaggttt tcgtaacagt
    92821 aaaataagac tgcttggcta atgagacaag tttttccact aagtagattc cacgcttgtc
    92881 agagatacgt ttagaggtag attgacggat gatagctgac aatgctttgt cagctagctc
    92941 cagtacaaag ctattacatg gaaaagccgt taccacattc cagtattact caccagttgg
    93001 tgcaaataag atgtgttcca gttcaggaaa agtgacttgt aagatcttgt gaaggcgatt
    93061 cttaactctc gaacgatatt atcctcagtc aatttttgat agaagcgact caagtcacgt
    93121 agcagctgat aaacttcttc ctgaacgtaa gttggttttc taactagaat aaattgagac
    93181 tgagccaatt tttcagtgtc taacttatcc gctttacgca cccgtagact atctagtttt
    93241 ctaaaggatt gagttgtgta taagcgtagc catttttctc aaggaaggac tgaagccgac
    93301 gagaatagac tcctgttgtg atggtctccc ttttgccttt taaacaatag tatagccgtt
    93361 tttcaagatg ttattaatga ttttttcctt tattctagaa gaataagtct gatactgttt
    93421 cttcttaata atctcaatgc cctaacagtc catcagtcga acggtatttc tcaaattact
    93481 gcagttgact cttgcgttca gttccctcac cttgtggatg ccgtttagaa caatattagc
    93541 ttgctgagcc ttttggtaat gtgaacaaag catctttatc actcaaggag aagacaggtt
    93601 cttgtggtaa gtgtccaaca aggtcacgat aaactcatcg taccgttttt ggcggaagtc
    93661 tagaaatgcc ttatgaatgt aagcctcaga aacgtctcta aaactaaaca agaaatacaa
    93721 gaacaaatgc ccttgattct ggtacaaatg ctgtatcagg ttcaggtatt gcctatctgc
    93781 gataatgaca ctctgctttt ccttaacaat atctttgaaa ggaatgattt cgacattgac
    93841 aggcataacc gttgcaatag ctggcgggaa gtaaatcgag agtgcattgg tcatcaaatc
    93901 cagcgcagca gtgttattgg tcaaaagata gacaggtatc ggtggcaaat atgtttttag
    93961 gagttcctct aactgtatcg tgaagagcag taaatgatag gacggcagtt tccccacgat
    94021 gccttctgcg ctcatccatt cctcaacgat ggtttttaga gtattgtaga agctcttgtt
    94081 tcgtttttgc tgtcttctga ggtaatggaa caagtgtatg tcaggtaaca aaacttgaag
    94141 attactgata aagagacgtg agaaggaaac caaaatccgt ttgaaaggaa gggagtttag
    94201 gatattattg cctagtagtg gacgcaggga tgctttcaag gtttttccat ttgtttttgt
    94261 catcaccaac tcaaacaatt ctttcacttt tttaggtgtc catttatcct tatggaaaga
    94321 attattggtg gtgcaaaaac ataagaaaat ataatccaaa tcctcatcag ttaaatcagg
    94381 atggtaccat tttccgatga tttcctgact ggtcattttg atatctcgat agatagacag
    94441 ttttttcaag tgtttgaatg catctgtctg agggatcccc aagttatcat gtcgccgttt
    94501 ccatataagg gatatcagaa tggcaaagta tgaaaattca taaggggctt tactggcatc
    94561 attaagtgtg atggcttgat tggagtttat aatcagcgaa accactttat tcattgatgt
    94621 tttatcaaaa tcataaatgg tcataccaaa ctgatagtgc aacaaggcga tcagaaagcg
    94681 gatacggtat tctggtccaa caacatggtt ttgccgaacg tttaaaccta cctttttcaa
    94741 gtatttccga caattggtcc tgatacggta agcggtggct tgggaaatat actctcgttt
    94801 aatgaagtcg tgtaggctca gctctcctgg ttcaattaaa aaacataaca tctttaagaa
    94861 tatcgaggtt tgatagagtt tcttaaaata aggcatttta agttggtagg tcttataggg
    94921 gatagaaaca gtgtcgtcac aaatggttaa ggtgagggtg tcttctaaat ccttaatcat
    94981 ttcaatgagt aagttgtaga cacgttgttt tttgagttcg gtttcctgac acaactggtc
    95041 tatggagact tcggaaacgt ctaacaaaat gttgagcagt gataatttat cttgtaattt
    95101 ggtttctaga tgaaggtgta acataactga actcctttca tttttatagc agaaactcgt
    95161 atttatttaa ttatcacata attacataaa acagtcaaat aattcaatgg tgacgcgtgt
    95221 ttaaggagta ttgagaatat catatataag caaaatgcag ctgaatattc ttaattttag
    95281 gtatgaaaaa gcgtcgggat tgataaaaaa tctattgaat tgggtaaatt taagttgata
    95341 taataagttg attagaaaaa ttaacaattc atttaaattc taatcaactg taacgttccg
    95401 gggcgtgtta aactgtctga acatagaaaa tacaggtttc tacggtgact aagataagtt
    95461 aaggaggatt ccttaaattc tgtgatagga acgtaaactc tctacaagag tagagcacgt
    95521 catcagtcag tctgggtgtc tactggctga caacgtcaaa taagataggc atgaaaaaat
    95581 aagggggaat acagaatgtt tttaaaacac caagatgtga aacaaaaaaa ttggagaatg
    95641 cgtaaggtca aaaaactctt tgttagttca tgtatgcttt taacagtcgg cctcggagtt
    95701 gccgtaccta ctgcattcag ccaatctaat ggcgtgatgg tcgtaaaggc tgcggaagct
    95761 gaagaactgc cagatgattt gatgaatttt aaaggaactt gggaagtatc tgccgatggc
    95821 tcttctggtc gcttcttttc aaaaggtgct acggatagtt atgtgttcca ccttattcca
    95881 gctaaagatg ttaaaaagcc gggatggcgt gaacataatg aagttaaaga tagctatatc
    95941 aaaatagaca agcaatctat tgcagctagg tataaaactt caacaaccgc tccatattct
    96001 gtagcgttta aggtcaacac taaatcttta ataaaagatc atgactataa gataactttt
    96061 gagcaaggtc agattgcgtc gggaataaca gttgattatc gtataggtag tgcttttaat
    96121 aaaactacag atgattcttt caaaatttca gatgagagta aatatgcttc taacgtaaaa
    96181 atagaaggtg aggaacaagg ttttaaacaa agggaacaag gagataaaac aatatctttt
    96241 agaactttaa aagaaggtcc tatgtctctt gtattgttat ctaaagttga gaaaaaacct
    96301 caaggagatc ttgatgtcga gtttaaaaac ttcaaaatta ttgatgttac aaacccaagc
    96361 caattagata aaggagttgc ttacgttgga aacaaaaatg tagaattgac attaaaatca
    96421 gacgatggaa gaacaaactt cgaaggtgat gagataagcc ttttcaactc taggggagag
    96481 ttgttacaga cagttacagt tacaaaagat caacaaaatc ctatatcaat aactttatct
    96541 gaagatcaag ccaaatcttt aaaaaataaa gaaaagttaa aagtaagcat taaacaaaag
    96601 caatcaaaaa agacttctaa ggactttttc tttgaggtag gaattgatcc taaagttgaa
    96661 gcaaagcaaa aagaaaaact cttggaacta gacaaagtta aaaaacaaat tgaagactca
    96721 atcaatggtg atgcatggct accagaaaaa ccggaaggcg aaaaaccagt acaaaatact
    96781 aataaagaat tacagttaca ggaactgaac aagaagtatc agatggccaa agaggcaatt
    96841 gaaagtgcta caactcttga cgatgttgaa actcagtttg ataaatacac aaaagttgga
    96901 gataaagata aatacccgga ttctttacgt aaccaatata ctcaaggaga taaagataaa
    96961 gaaatagaaa aagctaaaaa atcactgggt gatttaagcg ataaagtaaa tggaaagatt
    97021 gaagaagata aatggctatc tgccgaagtt aaaaaaaaac aacagcaaga attagaagcg
    97081 cgtaaacaaa aagtaaacga ctctcttaaa ggatctgata gtttaaaatc attgagagaa
    97141 acagtggaaa aagcttcttc taaaaatcag aaaaaaccag aatcttttga agatgtttat
    97201 gttcctggaa atgaagaaac tgaaaaaaca aaagttcgtg atatacttca aaaaacttat
    97261 caaaaaacag agcaaaatat tgaaacagat ccatggttga gtccggaaca gaaaaaagct
    97321 caaaaagaaa acgctaaaac aagattagat gcaggtttga aagctgtcga aactacagaa
    97381 agcttagata aacttaaaga agttgagagt gacttccttg ataaagaaaa agcaaaatct
    97441 attccatctc aacatcaagc aggaactcct gaagttgctc gcaaaacttt cttagataac
    97501 tttgaaaaag aagctaaaaa agagattgaa tcaattaaaa atgacgttac attaacagat
    97561 gctgaaaaag caacagctaa agctaaagta gaagcacaac ttcaagaagc taaaggtaag
    97621 gctaaggaat caaaatcgtt tgatgatttg aagaacattc aagataagtt caattctgaa
    97681 ttaccacaca caacaggtaa gccgcttaaa gatcaacaat ctgatgctat tgcagaatta
    97741 gagaagaagc agcaagaaat tgaaaaagct atctcagaag ataagacatt gtcaaaagat
    97801 gaaaaagaga aacaaattgc tgattctaaa gcgaaattag tcgctgagaa ggaaaaagtt
    97861 tctaaagcac ctgatgctga tgctgttaag aaagctcttg agtcaggtaa gcaagaaatt
    97921 gctaaggctt atgttccaca aaacttagaa gatcacaaga aaaaacttct tgcagagttg
    97981 aagcaaaaag caaatgatac tgaaaaagcg attgattccg ataaaacttt gacagcgaaa
    98041 gaaaaagaag agcaaaaagc gaaaacaaaa gaagaacttc aaaaagcaac agaagctgtt
    98101 ggagcaattg acaatcgtga agaactagat aaaaaagccc cagaacttaa gaaagctatt
    98161 caagattctc acgttaaagg agaccttgaa ggtgttaaga ataaagctat tgaagatctt
    98221 caaaaagttc atgacgaaac agttgctaaa ataaatggtg atgataccct tgacaaagct
    98281 actaaagaag ctcaagtgaa agaagctgac agagctttgg cagcaggtaa agatgcgatc
    98341 actaaagcag atgatgctga taaagtgggt gcagctgtta cagagcacac accaaaaatt
    98401 aaagcagcac ataaaactgg tgatcttaaa aaagttcaag aagaggctaa ccaagctctt
    98461 gacaaagcag ctgaaaaaga acgtggagaa atcaataaag atgctacact aacgacagaa
    98521 gataaagcaa aacaactgaa agaagttgag acagctctta ctaaagctaa agataacgtg
    98581 aaagctgcta agacagcaga cgctatcaat gacgcacgtg ataaaggcgt agcaacaatt
    98641 gatgccattc ataaagcagg tcaagactta ggtgctcgta agtcaggtca agtcgctaaa
    98701 cttgaagaag cagctaaagc aacgaaagac aagatttcag ctgatccaac tttgacaagc
    98761 aaagaaaaag aagagcaatc taaagctgtt gacgctgaac ttaagaaagc gatagaagct
    98821 gttaacgcag ctgacacagc tgacaaggtt gacgatgctc ttggtaaagg tgtcacagac
    98881 atcaagaacc aacataagac aggtgaccct gtcgaagctc gtcgtgaggc tcatagtaag
    98941 gaacttgata gagtcgctca agaaactaaa ggtacgattg aaaaagaccc tactttgacg
    99001 actgaagaaa aagctaaaca agttaaagac gtagatgccg ctaaagaaag aggcatggct
    99061 aagcttactg aagctaaaga tgctgatgct ttagacaaag cgtacggtga cggtgttaca
    99121 gacatcaaga accaacacaa gtcaggtgac cctgtcgaag ctcgtcgtgg attacacaac
    99181 aagtcaatcg acgaagtggc tcaagcaact aaggacgcta tcacagcaga tacgactttg
    99241 actgaagccg aaaaagaaac acaacgtggc aatgttgata aagaagcaac taaagctaaa
    99301 gaggaacttg ctaaggctaa agatgctgat gctttagaca aagcgtacgg tgacggtgtg
    99361 accagcatca agaaccaaca caagtcaggt aaaggtcttg acgttcgtaa agatgagcac
    99421 aagaaagctc ttgaagctgt tgctaaacgt gttactgctg aaattgaggc tgatccaacc
    99481 ttaacaccag aagtgagaga acaacaaaaa gcagaggttc aaaaagagct tgaacttgcg
    99541 actgataaga ttgctgaagc taaagatgca gatgaagcag acaaagctta cggtgacggt
    99601 gtcacagcga tcgaaaatgc ccatgttatt ggtaaaggta tcgaagctcg taaagacctt
    99661 gctaagaaag accttgctga agctgttgct aagacaaaag ctctcattat tgaagacaaa
    99721 acgcttactg atgatcaacg taaagaacag ttatcaggtg ttgatacaga gtatgctaaa
    99781 ggtatcgaga atattgatgc agctaaggat gctgcaggtg ttgataaagc atatagtgac
    99841 ggtgttcgtg acatcctggc acagtacaaa gaaggacaaa accttgatga tcgtcgtaat
    99901 gctgccaaag aatttcttct taaagaagca gacaaagtga cgaaactaat caatgatgat
    99961 ccaaccttga ctcatgacca aaaagttgat caaatcaaca aagttgaaca agctaagtta
   100021 gacgcaatca agtctgttga tgacgctcaa acagctgatg ctatcaatga tgctcttggt
   100081 aagggtattg aaaacatcaa caaccaatac caacatggcg atggcgttga tgttcgtaaa
   100141 gcgactgcca aaggcgatct tgaaaaagaa gctgctaaag tgaaagctct tattgctaag
   100201 gatccaacct tgactcaagc tgataaagac aagcaaacag cagcggttga cgcagctaag
   100261 aacacagcaa ttgcagcggt tgataaagcg acaacagcag atggtgttaa ccaagaactt
   100321 ggtaaaggca tcacagctat caacaaagct taccgtccag gtgaaggtgt taaagcacgt
   100381 aaagaagccg ctaaagctga tcttgaaaaa gaagctgcta aagtgaaagc tcttattgct
   100441 aaggatccga ccttaactca agctgataaa gacaaacaaa cagcagcggt tgacgcagct
   100501 aagaatacag caat
//
LOCUS       DAUGSW010000003        94672 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUGSW010000003 DAUGSW010000000
VERSION     DAUGSW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 94672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94672
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.003"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(19..750)
                     /locus_tag="VIB18_000212"
     CDS             complement(19..750)
                     /locus_tag="VIB18_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8765252.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYYQSSL"
     gene            865..1230
                     /locus_tag="VIB18_000213"
     CDS             865..1230
                     /locus_tag="VIB18_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEQ8765253.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            complement(1350..2570)
                     /locus_tag="VIB18_000214"
     CDS             complement(1350..2570)
                     /locus_tag="VIB18_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8765254.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGIAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            2944..4428
                     /locus_tag="VIB18_000215"
     CDS             2944..4428
                     /locus_tag="VIB18_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEQ8765255.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVTAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            complement(4533..4934)
                     /locus_tag="VIB18_000216"
     CDS             complement(4533..4934)
                     /locus_tag="VIB18_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEQ8765256.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKISLTMFVTGRRHNG"
     gene            complement(5019..5796)
                     /locus_tag="VIB18_000217"
                     /pseudo
     CDS             complement(5019..5796)
                     /locus_tag="VIB18_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            complement(5948..7339)
                     /gene="rlmD"
                     /locus_tag="VIB18_000218"
     CDS             complement(5948..7339)
                     /gene="rlmD"
                     /locus_tag="VIB18_000218"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8765257.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTIMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFIADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLTKVQPVDLFPQT
                     HHVECVSLLEKRS"
     gene            complement(7388..8839)
                     /locus_tag="VIB18_000219"
     CDS             complement(7388..8839)
                     /locus_tag="VIB18_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8765258.1"
                     /translation="MTKYPMGDLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRANAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKMLAKLGLR"
     gene            complement(9047..9538)
                     /locus_tag="VIB18_000220"
     CDS             complement(9047..9538)
                     /locus_tag="VIB18_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ8765259.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIENQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            complement(9531..10814)
                     /gene="aroA"
                     /locus_tag="VIB18_000221"
     CDS             complement(9531..10814)
                     /gene="aroA"
                     /locus_tag="VIB18_000221"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEQ8765260.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVARGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLQQMGGEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSRLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDTLNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            complement(10925..11890)
                     /locus_tag="VIB18_000222"
     CDS             complement(10925..11890)
                     /locus_tag="VIB18_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEQ8765261.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPTSAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            complement(11892..12752)
                     /locus_tag="VIB18_000223"
     CDS             complement(11892..12752)
                     /locus_tag="VIB18_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEQ8765262.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(12768..14051)
                     /locus_tag="VIB18_000224"
     CDS             complement(12768..14051)
                     /locus_tag="VIB18_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8765263.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            complement(14060..14602)
                     /locus_tag="VIB18_000225"
     CDS             complement(14060..14602)
                     /locus_tag="VIB18_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8765264.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            complement(14840..15031)
                     /gene="grab"
                     /locus_tag="VIB18_000226"
                     /pseudo
     CDS             complement(14840..15031)
                     /gene="grab"
                     /locus_tag="VIB18_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G-related alpha2-macroglobulin-binding protein
                     GRAB"
     gene            complement(15152..15565)
                     /locus_tag="VIB18_000227"
     CDS             complement(15152..15565)
                     /locus_tag="VIB18_000227"
                     /inference="COORDINATES: protein motif:HMM:NF013537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765265.1"
                     /translation="MGTAVAYAEEIPTTPILTLEVTERREAINKINRLSDQYPNDPEI
                     QATFEDTTNKILAFESADITEALIAEVNSEVTRLNEEKIARDAVDTAEKADAEKRHDF
                     LKQQDAVVIAIQELANIPAEKAFRQYANDNGVDGV"
     gene            complement(15828..16891)
                     /locus_tag="VIB18_000228"
                     /pseudo
     CDS             complement(15828..16891)
                     /locus_tag="VIB18_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137776.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16937..18727)
                     /locus_tag="VIB18_000229"
     CDS             complement(16937..18727)
                     /locus_tag="VIB18_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEQ8765266.1"
                     /translation="MTHLVDLRKKPYHLDDQAIAWVEETIASMSLEEKIGQLFVNMGA
                     SRTEEYLTQVLNDYKIAAVRYNKGMADEVWEQNYILQTKSKIPLLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGIEAAAVGCNASFAPIVDLTRNWCNPIIAS
                     RNWGSNVDQIITFSKEYMRGIMEHGIMPFAKHFPGDGIDERDHHLSFASNPMTKDEWM
                     STFGRIYGELTEAGLPGIMAGHIHLPNVEKEMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLMLPTAVEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILTEERLHDALRRTLGLKARLGLHLYEGRREEIMLPKEEAMTLINTKEAQAIADEVAD
                     KAITLVKDKQKDIFPVTPERYKRILIVNVEGHKGGFGAMIAGQKKRASDVVKELLEAR
                     GHDVTVWESTEERIMQLPESERAAAIANIYAQKQPISNLTDHYDLILNLVDVNSGGTV
                     QRIVWPAAKGTPDQPFYVHEIPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     EKLAGESNFTGVSPVDAFCGLIDTHLWREY"
     gene            complement(18844..19647)
                     /locus_tag="VIB18_000230"
     CDS             complement(18844..19647)
                     /locus_tag="VIB18_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8765267.1"
                     /translation="MTTKKEAFVFCVDSDGCAMDTMTYKHQLFFGPIAAEVFGVTNRE
                     VFLKEWDHVNLYSRTRGVNRFVGLVMGLDYAGLKGIDRLKDWVANTKSLSNASLEAEL
                     AKEASDDLQKALEWSNEVNRQIKAYEGEALTFPGAESGLEKLHQLGKVFVVSSANKEA
                     VEEEWHDQGLMAHVDDLYCQDCGKKEDVIAELLQKGYQKERLMMVGDSPGDLAAAEQN
                     QVAFFPILVGKEAQSWADLKEAVADAFVAGELSDLDFNSLKETFWYNLD"
     gene            complement(19916..20755)
                     /locus_tag="VIB18_000231"
     CDS             complement(19916..20755)
                     /locus_tag="VIB18_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ8765268.1"
                     /translation="MTRVIDFKDKVVIVTGAGGVLCGYMAKEFAKAGAKVALLDLNQE
                     AAQAFVTEIEAEGGVAKAYKANVLSKENLEEVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHEVGLPEETKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRGLLF
                     TEEGQPTARAEKILNNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(20770..21864)
                     /locus_tag="VIB18_000232"
     CDS             complement(20770..21864)
                     /locus_tag="VIB18_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEQ8765269.1"
                     /translation="MKMSFRWYGKQDPVSLEEIKAIPGMQGIVTAIYDVPVGQAWPLE
                     NILALKKMVEDAGLEISVIESIPVHEDIKQGKPTRDALIENYKTSITNVGKAGIPVVC
                     YNFMPVFDWTRSDLNHPLPDGSTSLAFLKADLEGVDPVADDLNLPGWDSSYSKEEMKA
                     IIENYRNNISEEDLWVNLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQD
                     AVERFLNLYDSPNNGITMCVGSYASDPKNDVIAMTEYALKRNRINFMHTRNVTAGAWG
                     FQETAHLSQAGDIDMNAVVKLLVDYDWKGALRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKTPDFGITVKTVGDK"
     gene            complement(21959..23356)
                     /gene="uxaC"
                     /locus_tag="VIB18_000233"
     CDS             complement(21959..23356)
                     /gene="uxaC"
                     /locus_tag="VIB18_000233"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEQ8765270.1"
                     /translation="MTFNDANFMLKNEAAKKLYQQIQDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLERSYGNPVYHWS
                     AMELKNVFGVEELLTQDNAEEIYHRLNAYLVDHKISPRKLIADSKVTFIGTTDHPLDD
                     LEWHQQLADDSTFETVVAPTFRPDEAFVEHRNFAQFVERLGTSTGSRITDFTTFMAAM
                     EKRIAYFAEKGCKASDISFAEIVFEKATPEALNQIMAQVLAGDTPSQLDINQWQTAVF
                     ADLCRLYKQYGFVTQVHFGALRNNHSGIFKRLGADVGVDSLGDQTALTSNMNRLLDNL
                     VQTDSLPKMIWYNLNPSYNIAVANTLANFQANEAGVASYLQFGAGWWFADTKLGMISQ
                     MNALAEQGMLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQAIGQ
                     MTKDIAYDNAVRYFN"
     gene            complement(23386..24003)
                     /gene="eda"
                     /locus_tag="VIB18_000234"
     CDS             complement(23386..24003)
                     /gene="eda"
                     /locus_tag="VIB18_000234"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ8765271.1"
                     /translation="MLTQLKENYFFAVVRGKTAEDAIEIAKYAVLGGIRNIEITYSTP
                     NASEVISKLSDDFKDDTSVVIGAGTVMTTELAKEAIAAGAKFLVSPHFSKEIADIANQ
                     EGNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     VDNVKEWKNAGAVAVGVGSALASKVATEGYNSVARIAQSFVSALD"
     gene            complement(24130..24801)
                     /locus_tag="VIB18_000235"
     CDS             complement(24130..24801)
                     /locus_tag="VIB18_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEQ8765272.1"
                     /translation="MARPLVEKTAERLLQLILERGYDVGAKLPNEYELAQDLDVGRST
                     IREAVRSLATRNVLEVRQGSGTYVSSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALAAQNATPKEIKELEKIVVEIEEAVTAGDPKHLQLDVTFHSMMAKFSGNIAMD
                     SLLPVINKSIHLINANYTNRQMKEDSLQAHRDILTAIKERNPIAAHDAMLLHIMTVKR
                     TAFLP"
     gene            complement(24843..26633)
                     /gene="uidA"
                     /locus_tag="VIB18_000236"
     CDS             complement(24843..26633)
                     /gene="uidA"
                     /locus_tag="VIB18_000236"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEQ8765273.1"
                     /translation="MLYPTLTKTRSLYDLSGLWQFKLGDHNPEDCLSTEDVMVVPTSF
                     NDVVVDKDKRNYIGDFWYERLVDLPKLAKDDELVLRFGSVTHNAIVYVNGRELASHKG
                     GFTPFEVVVPEELYQDHQIRISVRANNILDYSTLPVGNYSEERQEDGSMKKVVKENFD
                     FFNYAGIHRPVKLVVRPKTHISDITITSDLSDDLKTADLSIAVETSAAVDAIQVTILD
                     EERQVVGQTNDGHVKLDCVHLWEVLDAYLYTARIEISVDGQIVDTYEEPFGVRSVHVA
                     DGQFFVNRKLVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKEIGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEIPAVGLFQNFTASLDLTPKDMGTWSVMETKEAHEQAIQELVK
                     RDKNHPSVVMWVVANEPASHEAGAHDYFEPLVALYKELDPQKRPVTLVNIFMATPDRD
                     EVMDLVDVICLNRYYAWYVNHGDLAKGEAGLRKELLEWQSKFPDKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCDFYAMTHGVFDEIPNLVGEQVWNFADFETNLMIFRVQGNHKG
                     LFSRNRQPKQVVREFKKRWTAIPNYNYKKK"
     gene            complement(26656..27684)
                     /locus_tag="VIB18_000237"
     CDS             complement(26656..27684)
                     /locus_tag="VIB18_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ8765274.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLTQATSLECQFGGSELNVLSTLA
                     QLGHKVSLISAIPANDLGRMTKTFLFSRQISQDYIIEKGQRLGIYYYQKGFSLRASRV
                     TYDRKYSAFWESQLADYELEDVFAGADWFHVSGITPALTDNLYHLTHYLMTKAKTEGL
                     KVSFDLNFRASLWDSFQEARELLSPLVALADVCIGIEPLVLAGDGEKDLKDQLGLSRP
                     YEDQALLENVLSKLAKTYGVTSFAFTQREMGHTNEYLLKGYLYQDGNLYQTDKSGIQV
                     LDRVGTGDAFTAGLIHGMLQNEAPDKALAIAMASFKFKHTIEGDSNIITPADIDYLIT
                     DASYEIKR"
     gene            complement(27837..29381)
                     /locus_tag="VIB18_000238"
     CDS             complement(27837..29381)
                     /locus_tag="VIB18_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8765275.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNTSTNIYLFAFMFITY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGIMIDKTDTKFGKYRPILIAGNIITAL
                     SLILLLALNNVSEGMRFPLFILVLIVHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAVMLTTLMTGGQFVVSGFLVPKFGNFTLEFFNVLIYGTIVISAILGLLAVIGIWSKD
                     NKEYFGLGENTQKTELKDYMKVIKGNKPLQVLSIAAALVKFSVQFFGDSVVMVMLYGI
                     MFGNYALSGQFSLLFVIPGVLINILISSVARKKGLRFSYVASLQFGLIALAAFGVVLY
                     FGKVGDLSLSNINLYTICFIITYMLARYITQAPAGLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVVGAVLATIGFAKAFPTMETPLTPELKMATIILLVGIPF
                     VALSVALFLMRFYKLDKEEMVRIQEKIQVMKAASSKERVKDIARNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(29773..31032)
                     /locus_tag="VIB18_000239"
     CDS             complement(29773..31032)
                     /locus_tag="VIB18_000239"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8765276.1"
                     /translation="MRKIIINGGKALSGEVTVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLMAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
     gene            complement(31206..32402)
                     /locus_tag="VIB18_000240"
     CDS             complement(31206..32402)
                     /locus_tag="VIB18_000240"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ8765277.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            complement(32938..35316)
                     /locus_tag="VIB18_000241"
     CDS             complement(32938..35316)
                     /locus_tag="VIB18_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEQ8765278.1"
                     /translation="MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKINKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKASILVNHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTP
                     ELSEREKGYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDLNKM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            35520..36461
                     /locus_tag="VIB18_000242"
     CDS             35520..36461
                     /locus_tag="VIB18_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEQ8765279.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYTDMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFENGDLQTLRSGEISLSSWEN"
     gene            complement(36436..36639)
                     /locus_tag="VIB18_000243"
     CDS             complement(36436..36639)
                     /locus_tag="VIB18_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEQ8765280.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
     gene            complement(36734..38404)
                     /gene="dnaX"
                     /locus_tag="VIB18_000244"
     CDS             complement(36734..38404)
                     /gene="dnaX"
                     /locus_tag="VIB18_000244"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEQ8765281.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISMLALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTASYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            complement(38404..38901)
                     /locus_tag="VIB18_000245"
     CDS             complement(38404..38901)
                     /locus_tag="VIB18_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEQ8765282.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNTLANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            39046..39855
                     /locus_tag="VIB18_000246"
     CDS             39046..39855
                     /locus_tag="VIB18_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEQ8765283.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            complement(39908..40171)
                     /locus_tag="VIB18_000247"
     CDS             complement(39908..40171)
                     /locus_tag="VIB18_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEQ8765284.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(40251..40877)
                     /gene="udk"
                     /locus_tag="VIB18_000248"
     CDS             complement(40251..40877)
                     /gene="udk"
                     /locus_tag="VIB18_000248"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEQ8765285.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            40975..42060
                     /locus_tag="VIB18_000249"
     CDS             40975..42060
                     /locus_tag="VIB18_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8765286.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIILDEYDELLSDSQYDFV
                     QRISRYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEIALKNQQLHFIN"
     gene            complement(42171..43445)
                     /locus_tag="VIB18_000250"
     CDS             complement(42171..43445)
                     /locus_tag="VIB18_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8765287.1"
                     /translation="MKKLNVILVGLLSILMLSLAIAFINRWKLNEDSQRIVLAEKKKN
                     TSDLVIKAVKHIKKDQKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPKLQ
                     SSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVKDLVSGHLERIQ
                     EEVEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPD
                     FLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIG
                     SKVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPR
                     YLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDI
                     HQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(43540..44967)
                     /locus_tag="VIB18_000251"
     CDS             complement(43540..44967)
                     /locus_tag="VIB18_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8765288.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            complement(45152..46885)
                     /gene="ptsP"
                     /locus_tag="VIB18_000252"
     CDS             complement(45152..46885)
                     /gene="ptsP"
                     /locus_tag="VIB18_000252"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEQ8765289.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            complement(46890..47153)
                     /locus_tag="VIB18_000253"
     CDS             complement(46890..47153)
                     /locus_tag="VIB18_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEQ8765290.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            47546..47764
                     /locus_tag="VIB18_000254"
     CDS             47546..47764
                     /locus_tag="VIB18_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEQ8765291.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            47784..49943
                     /gene="nrdE"
                     /locus_tag="VIB18_000255"
     CDS             47784..49943
                     /gene="nrdE"
                     /locus_tag="VIB18_000255"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8765292.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFITELAGIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQAEDWKALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            50276..51235
                     /gene="nrdF"
                     /locus_tag="VIB18_000256"
     CDS             50276..51235
                     /gene="nrdF"
                     /locus_tag="VIB18_000256"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8765293.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            51210..52523
                     /locus_tag="VIB18_000257"
     CDS             51210..52523
                     /locus_tag="VIB18_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEQ8765294.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIGSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            52661..53803
                     /locus_tag="VIB18_000258"
                     /pseudo
     CDS             52661..53803
                     /locus_tag="VIB18_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(53895..54590)
                     /locus_tag="VIB18_000259"
     CDS             complement(53895..54590)
                     /locus_tag="VIB18_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8765295.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGVFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(54609..55370)
                     /locus_tag="VIB18_000260"
     CDS             complement(54609..55370)
                     /locus_tag="VIB18_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEQ8765296.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDISENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            complement(55367..55582)
                     /locus_tag="VIB18_000261"
     CDS             complement(55367..55582)
                     /locus_tag="VIB18_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8765297.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            complement(55943..58561)
                     /gene="alaS"
                     /locus_tag="VIB18_000262"
     CDS             complement(55943..58561)
                     /gene="alaS"
                     /locus_tag="VIB18_000262"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEQ8765298.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEYFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYDPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYNIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDIQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            complement(58948..60003)
                     /gene="prsA"
                     /locus_tag="VIB18_000263"
     CDS             complement(58948..60003)
                     /gene="prsA"
                     /locus_tag="VIB18_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8765299.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            complement(60066..60773)
                     /locus_tag="VIB18_000264"
     CDS             complement(60066..60773)
                     /locus_tag="VIB18_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEQ8765300.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADILLPD"
     gene            complement(60839..62035)
                     /locus_tag="VIB18_000265"
     CDS             complement(60839..62035)
                     /locus_tag="VIB18_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEQ8765301.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            complement(62411..64216)
                     /gene="pepF"
                     /locus_tag="VIB18_000266"
     CDS             complement(62411..64216)
                     /gene="pepF"
                     /locus_tag="VIB18_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8765302.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFA
                     GHLLDSSANLLKVTKTYLELARRVEKIYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAADFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADEIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            complement(64229..65191)
                     /locus_tag="VIB18_000267"
     CDS             complement(64229..65191)
                     /locus_tag="VIB18_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEQ8765303.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFCCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            complement(65486..66202)
                     /locus_tag="VIB18_000268"
     CDS             complement(65486..66202)
                     /locus_tag="VIB18_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8765304.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTESERQLIKTYLD"
     gene            complement(66276..67025)
                     /gene="nagB"
                     /locus_tag="VIB18_000269"
     CDS             complement(66276..67025)
                     /gene="nagB"
                     /locus_tag="VIB18_000269"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEQ8765305.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDV
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLDSPNQSLNLVRTKMRR"
     gene            67227..68255
                     /gene="queA"
                     /locus_tag="VIB18_000270"
     CDS             67227..68255
                     /gene="queA"
                     /locus_tag="VIB18_000270"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEQ8765306.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGHLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGSKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            68262..69482
                     /locus_tag="VIB18_000271"
     CDS             68262..69482
                     /locus_tag="VIB18_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8765307.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKEKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQALYTDNIPQTNY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(69596..70173)
                     /locus_tag="VIB18_000272"
                     /pseudo
     CDS             complement(69596..70173)
                     /locus_tag="VIB18_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S11"
     gene            complement(70170..70418)
                     /locus_tag="VIB18_000273"
     CDS             complement(70170..70418)
                     /locus_tag="VIB18_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765308.1"
                     /translation="MDADLAQMDALGLYYDDNHLSLVNTVKVYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            complement(70403..70630)
                     /locus_tag="VIB18_000274"
     CDS             complement(70403..70630)
                     /locus_tag="VIB18_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765309.1"
                     /translation="MLREKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGERQQTA
                     DLKMKKRLEKLFKNRYLKNLKRLSKLLWMQI"
     gene            complement(70797..71402)
                     /locus_tag="VIB18_000275"
     CDS             complement(70797..71402)
                     /locus_tag="VIB18_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEQ8765310.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIVNWKKVSELYQAAK"
     gene            complement(71499..72539)
                     /locus_tag="VIB18_000276"
     CDS             complement(71499..72539)
                     /locus_tag="VIB18_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEQ8765311.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKVDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            complement(72610..74853)
                     /locus_tag="VIB18_000277"
     CDS             complement(72610..74853)
                     /locus_tag="VIB18_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEQ8765312.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLIQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAKEVRNFKGFNYQT
                     FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGWTS
                     WHLETVR"
     gene            complement(74834..75496)
                     /locus_tag="VIB18_000278"
     CDS             complement(74834..75496)
                     /locus_tag="VIB18_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEQ8765313.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            complement(75696..76436)
                     /locus_tag="VIB18_000279"
     CDS             complement(75696..76436)
                     /locus_tag="VIB18_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEQ8765314.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKLAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            76476..77330
                     /locus_tag="VIB18_000280"
     CDS             76476..77330
                     /locus_tag="VIB18_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEQ8765315.1"
                     /translation="MKVDFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQIARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
                     KGKPNHDH"
     gene            77320..77598
                     /locus_tag="VIB18_000281"
     CDS             77320..77598
                     /locus_tag="VIB18_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEQ8765316.1"
                     /translation="MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(77622..79622)
                     /locus_tag="VIB18_000282"
     CDS             complement(77622..79622)
                     /locus_tag="VIB18_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEQ8765317.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLVFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESDRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(79750..81369)
                     /locus_tag="VIB18_000283"
     CDS             complement(79750..81369)
                     /locus_tag="VIB18_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8765318.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            complement(81676..83220)
                     /locus_tag="VIB18_000284"
     CDS             complement(81676..83220)
                     /locus_tag="VIB18_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEQ8765319.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            complement(83468..84163)
                     /locus_tag="VIB18_000285"
     CDS             complement(83468..84163)
                     /locus_tag="VIB18_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEQ8765320.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLALAFSKEK"
     gene            complement(84243..85634)
                     /locus_tag="VIB18_000286"
     CDS             complement(84243..85634)
                     /locus_tag="VIB18_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEQ8765321.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            complement(85825..86871)
                     /locus_tag="VIB18_000287"
     CDS             complement(85825..86871)
                     /locus_tag="VIB18_000287"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEQ8765322.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMELAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            complement(86972..87568)
                     /gene="recR"
                     /locus_tag="VIB18_000288"
     CDS             complement(86972..87568)
                     /gene="recR"
                     /locus_tag="VIB18_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEQ8765323.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            complement(88367..89146)
                     /locus_tag="VIB18_000289"
     CDS             complement(88367..89146)
                     /locus_tag="VIB18_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEQ8765324.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFATNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            complement(89270..89812)
                     /locus_tag="VIB18_000290"
     CDS             complement(89270..89812)
                     /locus_tag="VIB18_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765325.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            complement(89973..90494)
                     /locus_tag="VIB18_000291"
     CDS             complement(89973..90494)
                     /locus_tag="VIB18_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEQ8765326.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            complement(90602..91297)
                     /locus_tag="VIB18_000292"
     CDS             complement(90602..91297)
                     /locus_tag="VIB18_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEQ8765327.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            91536..92471
                     /locus_tag="VIB18_000293"
     CDS             91536..92471
                     /locus_tag="VIB18_000293"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEQ8765328.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAVFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            complement(92771..94633)
                     /gene="cadA"
                     /locus_tag="VIB18_000294"
     CDS             complement(92771..94633)
                     /gene="cadA"
                     /locus_tag="VIB18_000294"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEQ8765329.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQLASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLFWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
BASE COUNT        28795 a        19980 c        16686 g        29211 t
ORIGIN      
        1 gacaggggag gtttcttttt atagtgagct ctgataataa ggtgccaggc tttgcaattc
       61 ctcaggcgtc aggcgcctaa actccccttc tgcaaggcta gggtctagtt ttaatggtcc
      121 catgctgaga cgctgcaagt caagcactcc ctttccacag gctgctacca tgcgtttcac
      181 ctgatggaat tttccttctt gtatggtaat tttaaccaaa cttgtttgct gctgtaaatc
      241 actagcaagc acttctaaat gagcaggtag gcactggtga tcctttaagg aaatacctct
      301 agcaaaataa tctttatcag cttcagtcat gatgcctgct actttagcca agtactcttt
      361 cgtaacatgt tttttaggcg ataaaaggtc atgggctagt tgtccattat tggtcaagag
      421 caaaagtcca cgggtatcct tatctaacct acccacagga aaaactgctt tttgcctagc
      481 cgtgtcatct aacaactcca taacagtagc ctgctgtctg tcctgggttg ctgacacata
      541 ccctgacggc ttgtttaaca ggtaataaac aaaggattca tagaccaagg gcgtgccttg
      601 atacgtcacc aaatccttgt attcatcaat gtgtgctttg gcagaggttt caaccttttg
      661 attgacgaaa atagccttct tttttaagag aagtttgact tggctcctag ttccaacacc
      721 agttgccact aaaaatttat ctaagcgcat cataaccctt tcaaagaaaa ttcattatta
      781 agtataacat aaaaaaacag tagtttcatg actgtaagcg cttaatatat tataataggc
      841 ttatagaaac gaggagatta acttatgact atttattctc acacttatga aacccgtccc
      901 aatcattcgg ctaaagccat gggctcagga acgctgaatg tcctagctac tcctgctctt
      961 gttgctttta tggaaaatgc ttcttactta tttgcccaag aacagctcga cagtgacttt
     1021 acaacggttg gcagcgagat agctatccaa catttggcag cttcagccat tggagatcct
     1081 gttacaatca tcattacagc ccttaaagaa gaaggccgaa aatacgattt ccgcttggaa
     1141 gcttttgtgg gagaacaact cattggaaaa gcctgtcata ctagagttag ggtgaacagt
     1201 aaacatttta tggccaaagt agcggagtaa aacaaaagaa aagaaccaaa aaggtaagca
     1261 atccctaagt gcttaccttt ttgcttatct caatcaataa aatagttttg tgagtgaaag
     1321 taactcaaat actaacaccc atctctttgc taacgcaatt gttggtagcg ttctgctttt
     1381 aactgaccaa tagaccacat ggctccaaaa ctaatcacat acagagaagc taggaaaatc
     1441 atgaccattg aaatacctga ggcatctaaa atactaccaa tagcaacgga cgaaaaccct
     1501 cctagagcac ggccaacatt caaaataaca ttattagccg tggatcgaat gtgatgggga
     1561 taaagtctgg taatcatagc cccgtagcca gcaaacatcc cattgacaaa aaaaccgaca
     1621 atagcacctc caataaccat actcgccatg gaattggcaa attgaaaaag gtaaacacaa
     1681 atagatgatg ctaataaaaa gagggaataa atcagacgtg gaccaaagca atctaaaagc
     1741 tgaccaaaac acagcatccc caaacacatg ccgacaatag tagccaccat ccacaaggac
     1801 gaacttttta ctgaaaggtt taagcttgtt tgaataatgg ttggcaacca attcatcatt
     1861 ccaaaatagc ccgcaatctg cacagtcgtc atgaccatta aagcaagggt ttgagctgtt
     1921 aaggattttg ttttgaatag ttcattgatt ttaattggtt gactgcattc ttcctcctct
     1981 tgcccataat gatcccaaat tttttggtca tctatggcta aagtcatcca aatcaccaag
     2041 agaatcggaa gtaatccaaa gagaaaaagg ccacgccagc ctagacttgg agccagccac
     2101 cctgctaaaa gagccgaact aatggagcca agctggccag caataccatt taaagaagac
     2161 atccgaccca ttttttctgg tggtacaatc cctgccatta tagcaatggc tataccgtac
     2221 tcacctccaa ctcctatgcc agcaataaat cgcatcaggt acaagtaggg caaagactgg
     2281 gtaaaataaa ttaatcctgt tgctactgaa aacagtaaaa tcgtccattt aaagacctta
     2341 aacttgtggt gcctatcagc cagcaacccg aataagaggc ctcccaccaa cattcctaaa
     2401 ttggtaatgg tcgcaatcca gccaccctga gtgccactaa gacccaagtc tgtcataatg
     2461 gaagacatgg aaaaggcaag aaacatgaca ttcaagtcat ccgttcctga agctgcaata
     2521 gctgccacta aagctcgctt atttgtggtg tccaatgata atgttgacat aattgtctcc
     2581 ttcttaatag tagctcactg actaccttaa ttaattgaat accctttgtc caaaggtcaa
     2641 aaaaagactt ggaaacaagt ccgcaagtcc atcaaagttc actaaataat aagagatgac
     2701 aaaaaaactc tctttactgt taagactttc atgcttcacg gaacatgttt aaagtagtat
     2761 ttaattgtta ctagtatagt aaagctcatt ttaattgtca agttcttttg aacatagcag
     2821 atacattttt cttctaagaa ccaagcctaa gtttttttaa aaagtcacaa aatgaggtat
     2881 ccctgcaaaa aaccttttct ttcttggtat ttctttgtta taatgcttta cagaggtgaa
     2941 aaaatgaaga ctattgcttt tgattctaac aagtatttaa acttgcaaag agatcatatt
     3001 ttagaacgta tcagccaatt tgatggcaaa ctttacatgg aatttggtgg taaaatgtta
     3061 gaagattacc atgctgcccg tgtgcttcct ggctatgaac ctgacaataa gattaaatta
     3121 ctcaaagagc tcaaagaaca agtcgaaatt gtaattgcca ttaacgctaa taatattgaa
     3181 cattctaaag cgcgtggtga tttaggcatt tcttatgacc aagaagtctt tcgcttaatt
     3241 gacaaattta acacgttaga tatttacgta ggttctgtcg ttattactca atacaataac
     3301 caacccgctg cagatgcctt tcgcaagcaa ctcgaaaaaa atggcattgc ttcttacctg
     3361 cattatccta tcaagggcta cccgacagat attaatcata ttatctcatc tgaggggatg
     3421 gggaaaaatg attacatcaa aacgagtcgt aaccttatcg ttgttacagc accaggccct
     3481 gggtctggaa aattagccac ttgcatgtcc caaatgtatc acgaccaaat caatggggtt
     3541 aagtctggct atgctaaatt tgaaaccttc ccagtttgga atcttcctct tcatcaccct
     3601 gtcaatctgg cttatgaggc agccacggca gacctagatg atgtgaatat gattgacccc
     3661 ttccatttgg aaacttatgg caaaacggcc gttaattaca accgtgatat cgaggtcttt
     3721 cctgtcttaa atcggacctt cgagcgtatt ttgagcaagt ctccttatgc ctcaccaacc
     3781 gatatgggtg ttaacatggt tggtttttct atcgtcaatg aagaagctgc tatcgaagct
     3841 tctaaacaag aaatcatccg tcgttattac caaaccctcg tggattttaa ggcagagcgg
     3901 gtcacagaat ctgctgtcaa aaaaattgag ctcttgatga atgatatcgg tgtcacccct
     3961 gacgatcgtc acgttactgt aactgctcat caaaaagcag agcaaacagg ccaacctgcc
     4021 cttgctctcc aactaccaaa tgggcaaatt gtgacaggta aaacatctga actctttgga
     4081 ccaactgcag ctgttatcat caatgcgatt aaaaccttgg caaagattga taaaaccact
     4141 catttgattg aacccgaata cgtgaaacct attcaagggc tcaaagtgaa ccacttaggc
     4201 agtcacaatc cgcggcttca ttccaatgaa attctgattg cgttggccat tactgctatg
     4261 actagtgaag aagctaatct agccatgaaa gaacttggca atttgaaagg tagcgaagcc
     4321 cattctaccg ttatcttaac cgaagaagat aaaaatgtac tccgaaaact tggggtaaat
     4381 attacctttg accctgttta ccaacatcac aaactttacc gtaaataaac cataaccacc
     4441 cgtctaacgg gtgatttatg gtatctctca ataaaggaaa aaagttccaa ttctcagaga
     4501 gttgggactt ttttccctta ttgattcatt aatcacccgt tatgacgtcg gccagtcaca
     4561 aacatggtca agcttatttt tgttagaaga gctcctgttt ggttatgaat cgtcacatca
     4621 accacctgcg tggttcgacc tccatgaacc aatcgacctt caaccatcag cttgtctccc
     4681 ttgtgccctg cttttaaata gttagcattg gcctgtaagg tgacagattc tacgccagta
     4741 gttctagcaa ccaaaccacc tacttgatca catagggtga aaagataacc accatgggca
     4801 ttcccataat aattcaaagc cgtctcagtc acttcagtac ttaaaataag gtgtcctttt
     4861 tcagcaagtt caatttggta attatcaaaa atactaataa catttaaggt catctcttgt
     4921 gttaaatctg acattgtttt tctcttttct aagcttagtc taaaagcaat acaagcctca
     4981 ttatactaca aataggaaca gaaggcagag ctcatgtttc aaaaatcagt agcctttcca
     5041 tccttttcta gcgtattgag cacttccaag cataaatgaa gcgcaaaact aaaggaatca
     5101 gcgccccagt tgcgttgatc gtaaacctct acatctgcta gagtatctgc tgtaaataag
     5161 agttgccccc aaaggatgcc tcttaattga gctactgctg ctaaggcaga acattccatc
     5221 tcaacaaccg aacacccttc ttcctggcga taagtcactt tttctttggt ttttcggtaa
     5281 aaccatctgt tgaccaggtg atgacctctt gataagctaa cccctgtgct aaaagcgttt
     5341 tctcaatcag tataagcatc ttaggatcaa tatcaatata acgagatggt gccacgtaat
     5401 gataacttgt tccttcatct cgcaaagcct taactggcac taaaaaacgg ttttctgcga
     5461 taggaaccaa aacgccacag gttcctgtac tgatcatttc tttaacccca taaccaatca
     5521 gtcagtccat gaattgcgcc gcaggagctg agccaacggg agcttgagct aggcaaatgt
     5581 cttggtcttt ataagatatc tgataaatag ggtaaacctt tgtggctgaa atgaattctg
     5641 ctactttttt accttgatgg tctaaagcaa aagcttcaat ctcgtcttct aagaaagcgt
     5701 agacacactt agctggaagc taaatagcta gataatgacg gctgatggat tactatcaca
     5761 ttctaaaagg ggaatctcgt gtttggtaat aggcattcgt ttctccttat ttttgtcatg
     5821 tggaggcagc tacattactc cttgattagc aacactacgc actcgacgtg atgggtctgc
     5881 gggagtcaaa aggtccagtg gaccttttga gcgtctcacc ttgaaataac agagtgaggc
     5941 ggactcttta actccgtttc tcaagtaaac ttacacactc cacgtgatgc gtctggggaa
     6001 acaaatctac gggctgtact ttggtcagtt tgtaacccaa ctcttgataa cgcttgatgt
     6061 cacgcgccat ggtggctggg ttgcaggaaa cgtaggtgat tttttgtggt cccattgcca
     6121 cgctggcttg gatgaaactt tctgttaagc cttttcgtgg cgggtctacc agaataacac
     6181 ttggtttaat gccatctttc gcccatgttg ccatggcatg ttctgcggta tctgcgataa
     6241 agtaggcatt ggtgatgcca ttaagagcgg cgttctgttg agcatctcta acagctgctt
     6301 caatcacttc aacaccataa acagctttaa ctgttttagc aaatgatagg ccaatggttc
     6361 cgatacctga gtaggcgtca atcacaatgt catctttaga aaggtctgaa aaggctatag
     6421 ctgtttgata gagtttttct gccataatcg tattcacttg gtagaaagac tgagcagaaa
     6481 tggcatagtt gtttccaagc atgctatcag taatggtatc cttgccgtaa agcgttttga
     6541 aatctttacc aaagattgca ttggtgttct tatcattaat attttgaata atagacacca
     6601 ctgctggaaa agcttcaacg attttttcaa tgacttggtc aacacggaaa acttttgggc
     6661 gtgtagtcac taagaccagc atcatttctc cagagtaatg gcctcggcga acaacaatat
     6721 ttctcaagag acctgtttgt tctgtttcgt catacggttt aatatcaaag cggcgtaata
     6781 aatcacgggt aaaattaatg agacgatcaa tctctttgtc ctgaatataa taatccgaaa
     6841 taggaatcaa gtcatgagaa tgcttgcgga aaaagcctgt ttctagctga ccgttaacac
     6901 gtctaacagg aacttgagcc ttatttcggt aagctaaagg ttctgtcatc ccaatcgtgc
     6961 tttcgactgt cacgtcactg attccagcaa ttttatagag gctgtcctga acttgtttct
     7021 ttttgaaagt cagttggtct tcataagtta gatgtccaag gtctgcaatg cctgttcgca
     7081 aataagttaa attgacatct gcatttctag ctggcgacag gtaatgatag gcttctactt
     7141 tgccaaaacc gctgttttta ttgaccttta agacacgcat gtcaatcact tcttctggca
     7201 aggcattatc aacaaagaaa acaaaaccat cgtgtttagc gacacctgct ccctcatggc
     7261 ttaaatctga aatagcaact tggataatat catttttttt caacattctt attctttttc
     7321 cttttctagg gctaaccatt gctcaaaaaa gaagagcaac tttagttact ctccattata
     7381 ccatatctta gcgcagacct aatttggcta acattttctg atacttatca aaatctatgt
     7441 aaagggcttg tcctccatac atatcgtatt cgtcaaccca atccccgttt tctggaatgg
     7501 tcacgtgctc aactccattt ttcccacttc ctaaaacaga aacaccattt ttaacaacaa
     7561 atgggaaaga aacattggtc gaagtcagcg catagatttt accaatagcc gcagaccctg
     7621 taaagagttt agttgggtcc ttgatttggg acataacagc tgacataacc tgttgctgcc
     7681 ggacggttcg tccgaaatct ccttcgtcat ctttacggaa acgagcatag ttgagcaagg
     7741 ttctaccatc catgcgttgt tctccaactt cgatggtttg gttgggaaca accccatttt
     7801 tcattcgcag gtcatctgga acttctacgg agtcaacagc tacaccacct actgtcgcaa
     7861 atttggcatc aatcttaaca ccatttggaa acaaggtgtc aatagcttct gcaaatgttt
     7921 caaaatctac catcacataa tacttaatgt cgatatcaaa attatgtttt aaggcccgtc
     7981 gaacgtactc tgctccgtgg tgatcttctt gctctccaag attaaatgca ctatttaatt
     8041 taagatcata cgaattatca ttataactgt atcctggaat gttaatcaaa gtgtcacgca
     8101 taaaagagac catttttatt tttttagcat ggttgccgac attgacaacc ataatggtat
     8161 ctgtgcgagc atctgtagaa ccttgagtaa ctcgttggtc agaacccaaa accagaatgt
     8221 tcgtaccatc ttgagtttct tgaccatcaa aagcttggga aacagctggt ttgtaattag
     8281 ctttattagt agaaatatca aaaacccctt ttgcaaacat caaccctaac cccataagca
     8341 cagtcattag caataagcca agaatgttaa aaaaccattt catacatcct tttttcttat
     8401 gctttctttt ttgagatcta ggaagagcac aacgagcaac agactctgtt aaaaaagcat
     8461 cgtcttcatc aataggctgc ggagcatcta taggtctacg agctgtaagt tttgtttttt
     8521 tgtttaaata tctgtcttct ttaggatata tcggtaaacc atatggaaca aaagaagagt
     8581 catgattgac gtcatcatct tctagtaaat catttggtga gtagtcgtta tagtagtcat
     8641 cttcaaagta aggttcttgc cgttttgact tcctataatg ctgcttagaa ggagcattag
     8701 ctcgaccaat ttccaattta gattttaaaa aagcaaactc ttttttttca ttctcactaa
     8761 ggtaactcaa attccttagg agataaaaat aacgtaattc ttcatggtga ctaaggtcac
     8821 ccatggggta ttttgtcata tcttatcatc tcttagtatt acaattgcac ttttaacgaa
     8881 tactaccatt ataacctata ttagccagat tgtcctctca aaattttaat cattatagaa
     8941 taatcaagat tatttcctaa tatttaataa agccaacttt ccataagaag tgctttagac
     9001 agatacctgt ttaaaaccat aaatatcaga ttacgacaat gacctactaa taaccctcaa
     9061 tgatgttggc aacttcttca ggcgtacgat ggtcaactct gattactaaa tctgaaagtc
     9121 cctcataaaa taccatacgt tgttgataaa attcataaaa tgcttcctta gagtacttaa
     9181 gaaatagagg tctttgagac tttttatcat gttttaaacg ctggtacaaa gtttcaaaag
     9241 aagctaccaa taaaatatta tgctggtgat tttttctcag taattgtcga ttttcttgta
     9301 aaaccactac accgccacct gttacgatga cactattatc atttgcaaac aatagatctt
     9361 ttaacacttg attttcaatt gttcgaaatg ctatttctcc atgctgttca aaaaaagctg
     9421 caatagacat accgatttta gcttcaataa tagcatccat atctttacag tgcatactta
     9481 ggtgtttcga aaccgttgtt ttccccactc ccataaatcc caataacact ttagtcatga
     9541 cacagccttt ctaaatcttt gaaaaacgtc ggataagacg tcatgatggc ttcttcttta
     9601 tccaaatgaa cctgtccttg tttaacaagc aaggctgcaa ttgctgtcat cataccaata
     9661 cgatgatctc cataggtact tgtgttagcc ccatatagta ccgtagggcc tttgataatc
     9721 atgccatctg ctgtcgcttt gatattagct cccatactgt taagagtatc agttactact
     9781 tgaatacgat ctgtttcttt gactcgtaat tcttgagcat ctttaataca ggttgttcct
     9841 tgtgcttggg ttgcaagaag tgcaatgatg ggaagttcat caatcaatcg agggataaga
     9901 cctcctgata tgatagttcc tttcaagcga gaatatacca ctcgaatact agttacttgc
     9961 tctttcttat tcatatcttc atagacaatc tgtgctccca ttttttcaac cacttcaaga
    10021 atccctgttc gtgtcggatt gactccaaca ttctttaaaa ggagctccga accaggaata
    10081 attaagccgg cgacaagcca aaaagctgca ctagaaatat ctccggggac agttatctct
    10141 tgagcagtga gctgctgggg tcccaccaaa gtaatgcgtt taccatcaac tatcaatcgt
    10201 ccaccaaatt gttgaatcat ttcttctgta tggtttcgag taatctcttt ttcaacaacc
    10261 tgtgttgttc cttttgcttg caaagctgct aataaaatag ctgacttaac ctgagcagaa
    10321 gagataggca aggtatatgt gattggttgt aaattacgat taccttgcaa ttgtagtgga
    10381 ggaaattgcc tatctgtttc tccagatatc tcacccccca tttgctgtaa cggataaaca
    10441 atccgatcca taggacgttt ggataagctt tcatcgccaa tcattttgac actaaaaggt
    10501 tgacctgcca ataatccagc aatgaggcgc atagaggttc cagaatttcc catattaagt
    10561 gtctgacaag gagcggtcaa tccttgaaaa ccttgacctt ctatcacaag ctggtcatct
    10621 ttttcttcga tacggacccc caaattccta aaggcttgaa tcgtggaaag cacatcttct
    10681 ccttttaaga gtccttttac tcgtgtttcc cctctagcaa cggctcctaa tatgactgcc
    10741 cggtgactaa tggacttgtc tcctggaact tgaatcgttc cctgtaatgg tcctgcattt
    10801 gttcgcaatt tcatccgttt catctgcctt tctatttgct aagatcaatg attttctatt
    10861 tatcctcata aaaaatgaag caagaaaata gttactcact ccacgactta ttatcttttt
    10921 tgtatcaatc agtgtgacta tcttcgatag actgtgaagg agatagatct gaatcattcc
    10981 caagtgtttt tttaaggata gcgatcatat caccactacg accttctaat ttccccaagg
    11041 acatttcttg ataggtcgca ttaaatatag ctcctaaaat caggattctt gctaagaaaa
    11101 taaaccatag catgatgata aaaatcataa ctgaaccaaa cattttaata tctaccatcc
    11161 gctcaacatt atacacaacg taattgccaa ccagattact caaaaatgtc atcacaaaag
    11221 atgtaaatag ggttcctggt aaaatgtagc gaattttttt aatcttaaca ttgggtaata
    11281 aaaaatatag tagcatcaag ccaacaaaaa taatcaaaac tgtaataggt tgaatgagga
    11341 gtaagaaaat cgttgtgata ttatcactca aatggtaatg cttatccagc acttgaatag
    11401 cagctttaga aaatgttgaa aagattaagg caaaggctaa taaaaataaa ataattaaac
    11461 tggtcaacaa accaaccaag tgtccgataa agaaatctcg atgctgagaa gcgccatagg
    11521 ctttattaat agctttttgc agcgatgtca aacttcgaga cattgtccat aatcctgtca
    11581 aagtcgctac tcccaaaaca cttccagacg gtttagagaa aatattttct acaattgcag
    11641 aagtcggtct aaaaatatct ttaggcaaat tttgcttcat taaacgtaac aaatcagcaa
    11701 tatcaatatt gaggtaagga aaaatattgg ctgcaataac aattaatgga aaggccgtta
    11761 agataaggta atacgcaacc gcaatggcag ataaatccat ttctgcactt tgtaaatgcc
    11821 tcataaagac ttgaatgggt tcatactgcc acttggacag taccttatca aaccattttt
    11881 tttctgccat tttagtaagt tctttcttct ccttgacttg ttaaaataac gggaccatct
    11941 ttagtaatca caaattggtg ttcgtattgg caagataaac caccatctag ggttttatga
    12001 gcccaacctg tcttgatgtc ggtatcaatt tcccaagttc ctgtattaat cattggctca
    12061 acagtcaaga ccatgccttc ttttagacga agtccacgac ctgctgttcc atagtttggt
    12121 accattggct cttcatgcat tgtaggacca acaccgtgac caacaagatc acgcacgaca
    12181 ccataaccga agctttcagc gtattcttga acagctgcgc caatatcacc aatacgattg
    12241 ccaattactg ctttttcaat accacggtac atggcttctt tggtgacatc cattaattgc
    12301 tttatttcgt cagacggtgt tccaacagca taagcccaac aagagtcagc taaaccaccg
    12361 gtataagatc ctgtccattt cttcatctca ggcacgttat caaaatctaa agctgctaca
    12421 tcaacaattg atttatccaa aggctcactg agtaccatgt caactttaag caaatcccct
    12481 tctttcagaa tgtaatgacg gggaaaggca tgtgctactt cgtcatttag accacaacag
    12541 gtcgcataag gatagtccat catgtgacca tcaaccccta tttgcaaagg aagaacgttg
    12601 tcttctttac aacggcgacg aacatatgct tccacttccc acatatccac accaggctta
    12661 ataatatccc ttaagccaat atggatacct gctaagaagt ctcctgctct atccatcgct
    12721 tctatttcac gggctgattt taatgttatc attgttttgt tactcctcta atttattttc
    12781 gttgtaataa tagctttagc aatcacttga tcatccacaa aaatttcaat atcaatggtg
    12841 ctgcttcgtc tattttcagt aatgatttta ggatatattt ttaattcatc ctcaatttga
    12901 atagcatgta aaaagtatac catcatttgt tcgataatga tatttttttg gtgctttttc
    12961 gtgagggctc tgatactaat ttcctttaag aactctgaaa taacaccgtt tgacatgtta
    13021 ccagcactat caatcattgt tggctcaact actacttggt aataatcaac cgtttcttca
    13081 aggttagaaa gtatttgctc actataagta taggggttat ttggttggtg atttggcaaa
    13141 ttttccattg cttgtctacg agtaatcata ccaagtaaat tgttttcttc gtcagtgaca
    13201 ggtaacatgt ttaaatcttc aaagatcatt ttctggctaa tattagcaag actagtattt
    13261 ggtctagccg ttattggatt tttagacatg accttggtaa gcttagttgt tggcaactga
    13321 tccaccacat cacgcatact aactacacca atcacttttc ttttataatc taatacagga
    13381 aacctgactt gtcgtgtttt ttttattaat gtattgaatt cttcaacaga gctgtcttcg
    13441 caaaggtaac cataatctgt aataggtatc attacctgtt caactgtttt gagatctgtt
    13501 ttaatacgaa tattagatag cgcgtgatta atcattgtag ccacagtaaa ggtatcataa
    13561 tgagttacca taactgggat tcgttggtta tttgccattt caataacacg tttggatact
    13621 ggaaatccgc ccgttaccaa aatggcatta tggttttcaa gagctaagag ttgaatcgtt
    13681 tcacgatccc caactattaa taaccctcct ttgaccaagt aacgacgaat attttgttga
    13741 gtcatagcac caattgaaaa cctactaaat tcatgtccta aaccagcatg tcccgctagc
    13801 acttccgaat cactgatccg agcaatttcg gaataggtca gacggtcaat acgaacccgt
    13861 cctttttttt caatacgaac agttccactt cttggtttgg tttcgacaat acctcgattt
    13921 tctgcctctt taatagcacg gtaggctgtt ccatcgctta cttttaagtg gtttgaaatg
    13981 cttctaacac tcactttttt accaatagca agtttttcta aataatctaa aatatcttga
    14041 tgtttgctca taatgattat cacctatcat tagttagttg gtacatttta taaatgcaga
    14101 ttttatgagt attacgatcg cttcctttaa aacaggtttt tagttgaaag cctgcttttt
    14161 tagctacttt ctggctggcc ttattttcta aatgagttat aatacgcaac gttttgagac
    14221 caaattcgtg aaaagataaa taaacaagtt ttattacgac ttctgtcata attccttgtc
    14281 cccaaaaggc atagtttaaa aaatagccaa tatcagcaca acgcgtttta gcatcataat
    14341 gctcaattct aatagaacct attacttggt gggttgcttt atcttctatt gcccactgac
    14401 ctaaaggaaa ctttataaaa ctatgtacta aaagatagtc acttgctgcc ttagtttttt
    14461 gttctggaaa aacataataa aggtttttag tgtcgttaac catgctgtaa aaatcccaat
    14521 gatcttcata gcgaaaaggc cgtaatatta ctttcggagt ctcaaaaaaa gcaaacactg
    14581 caagctttgt ccaaatatcc atattatacc tttcacaata cctgtattgg gtccattata
    14641 acaaatcttt tgcaaatatt ctataacagt cttagtcttt atctatcctt tgatacaact
    14701 gggttagttt tattcaagct tgttctaatg agtttgagaa catttagtct ttcaagctat
    14761 tataaactgt agcattttta aatatcagaa aaagagaatc tttcgattcc cttgtttcat
    14821 ttgctagaac aaatagcaac taattttctt tgcactttga acttacaact aacacacctg
    14881 tacttaccat tattgcaagc gcagcagctg taaagaatgg gttagactct tcaccagttg
    14941 taggaagggt attaacgttt tgtctttctt cttttttaac tacaggtttt gtatctttag
    15001 ttttcttaac atctaaagcg attgaagttg ctggtgttaa tggaacaaaa ggaatttctg
    15061 cttttagttt ttctggttca actagagcat ctccaggaat ttcagtaact atttctgtta
    15121 ctgtaaacgt cttagtagcg tcgtcgtaag atcaaacacc gtcaacacca ttatcattag
    15181 catattgtct gaaggctttt tcagcaggaa tatttgccaa ttcttgaata gcaataacaa
    15241 cagcgtcttg ttgtttcaag aagtcgtgac gtttttctgc atctgctttt tcagctgtat
    15301 ctactgcatc acgtgctatt ttttcttcat tcaatcgagt aacctcagaa tttacttcag
    15361 caataagtgc ttcagtaata tcagctgatt caaatgctaa aattttatta gtcgtatctt
    15421 caaaagttgc ctgaatctca gggtcgttag gatactgatc acttaatctg ttaattttat
    15481 taatcgcttc tcttcgctca gtcacctcta aagtgagtat tggagtagta gggatttctt
    15541 ctgcgtatgc tactgctgtc cccactacaa acgcagcaga cgattaaagt taaacagtta
    15601 acttttacta ttagttaatc aaattattat tacaataata tcattagtat atagctacct
    15661 taatttaatt tttagacaat tattttataa gcgagcgact tattaatttc aaaaagatta
    15721 tattttcatt ttatactttt attaactcat tttatagtca ggggttttcg tttttgagaa
    15781 acaaaaaaag ttagaagatc cttctaactt ttccatcatc atctttatta cagcttggct
    15841 tgccacttat tggcccaaac taactcatta ggttgacctt taaaagctgc tttgccttct
    15901 agacaatcca aaagggctgc aatcgtatta gtattatggt gataagcatt aatcgctgtt
    15961 ttgaccatag tggcatcgtg cagatgcgtc ttgtaattaa gggaaataaa gacagttgga
    16021 acttcataaa cgtaccaagg cacctcatta aacatggctg tctcccattg gatacggtaa
    16081 ttattttgag cttcatagtc aacaacattg accaccgtca aggccaaatc cacgtcatta
    16141 cgataggcca agatctctcc cttgacgcga gtcgtgccat cattaatcgt cacctcgtaa
    16201 cctcttgcct ctagggcctg tttaaggttt ccgaccactt gatcattggc actcataatt
    16261 cctcctttcc cccctctaag caatagaggc gaatacgtct gtgagtttct gggctaatcg
    16321 ggaggttttc ttgagtatct tttaaaagga taatggtttt ttgtgcagct tctttttgcc
    16381 aaactaatgc tcttcacagc cagtgatagc aaggtcttca ggagatttaa gaagactgcc
    16441 atcaaagtta atattgacgc ctagagcttg tttcttccct agcagaaaca agccctgcat
    16501 agtaaacaag ccaagggtca tggctagcct cggattgagc tcgtgaagca atgtaggtcc
    16561 caccttttac cgcactatct ccacgagagt cacaactggc tgcgactagc aagggaatct
    16621 tgctgtggct ctgcaactca tttagaagtc cttgcatctg ttcaggggtg ccgttcattt
    16681 aacgagcgcc accgatatga tagtttgcca agatatcttt gttgcttaat tgattgcttc
    16741 taaacacatc ttcaccaaag aaaaaaagat ttacaaaaag ttgtccaatt ttctcttcat
    16801 cacttaatcc tgctaaggta tcttctacca aagcaacttg ctgatcgtca agctgatagg
    16861 ttttttgcct taagtcaact gtttttggca tgccttacgt cctttactac tctcacttac
    16921 tcaaacaatg actttcctaa tattctctcc ataaatgcgt gtcaataagg ccacagaaag
    16981 catctactgg tgaaacaccg gtgaagttgg attcgccagc caatttctcc accaaagctt
    17041 tcatggtatt gtccttaccg tcgtaagcat tgatataagt ccctacttgt ggcatgtctg
    17101 ctagggcaaa ggcatgctga actgatacca caattgttgg gatttcatgc acataaaatg
    17161 gctgatccgg tgtaccctta gctgctggcc agacaatacg ctgaactgtt ccaccagagt
    17221 tgacatcaac aaggttaagg attaaatcgt aatggtctgt caaattggaa atcggttgtt
    17281 tttgggcata aatattggca atggctgcag cacgttcact ttctggcaat tgcatgatac
    17341 gttcttccgt tgactcccac actgtgacgt catggccacg cgcttctagc aattctttga
    17401 ccacatcgga tgctcgtttt ttctgccctg caatcatcgc accaaaacca cctttgtgac
    17461 cttctacatt gacaatcaaa atgcgtttgt agcgttcagg cgtgactggg aaaatatcct
    17521 tttgcttatc tttaacaaga gtaatggctt tgtcagctac ctcgtcagca atagcttgcg
    17581 cttctttagt attaatcagt gtcatcgctt cttcttttgg tagcataatc tcttcacgac
    17641 gaccttcata taaatgaagt cctagacgtg ctttcaagcc aagcgtacgg cgaagggcat
    17701 catggagtcg ttcttctgtc aaaataccag cctcatagcc ttctttcatc cattgcaagt
    17761 cttcatctgg atcattaaag aataagaaga ggtcacatcc cgcttccacg gccgttggta
    17821 gcatcaaacg acgtggcata gaagctgtca tggcaaccat gtgagaagca tctgtgacaa
    17881 tagccccatt gtaaccaagc tccccgcgca gcaattcatc caacaacgtt ttgttgagtg
    17941 aagctggtag catgtcatcc aattcacgct caggatgcat ttctttctcc acatttggca
    18001 agtggatatg acccgccata atacctggaa gaccagcttc tgtcagttct ccatagatac
    18061 gaccgaaggt agacatccac tcgtcttttg tcattgggtt tgatgcaaaa gagaggtgat
    18121 ggtcacgttc atcaatcccg tcccctggga aatgtttggc aaatggcata atgccatgct
    18181 ccataatccc tctcatgtac tctttagaaa aggtaatgat ttggtccaca tttgagcccc
    18241 agttacggct agcaataatt gggttgcacc agttgcgtgt caggtcaaca ataggagcaa
    18301 aggaagcgtt acaaccaacc gctgctgctt caatccctgc aatgcgcccc atttcgtaag
    18361 cgtactttgg atcatttgtt gcggcaacct taatctcgtc cccaaccttt gtaccatcat
    18421 taactgcgcc atcgccaccc gcttcggtgt tagcagcaat taagagtgga atttttgatt
    18481 tggtttgtaa aatgtagttt tgttcccaaa cttcgtcggc catgccttta ttgtagcgaa
    18541 ccgccgcaat tttataatca ttaagcactt gggtcaaata ctcttcggta cgactagctc
    18601 ccatgttaac aaataactgc ccaattttct cctccaagga catggaggca atggtttctt
    18661 ctacccaagc gatggcttgg tcatcaaggt gataaggttt tttgcgtaaa tctactaaat
    18721 gtgtcatttc ttttcctttc aagagggtct cggtttttta ataccttctt accaaatccc
    18781 tctacttact tcttttctca tccttttgga ctagtcaatc taattagtag ctctgctatt
    18841 gatctaatct aagttatacc agaaggtttc tttcaagcta ttaaaatcta ggtcagacag
    18901 ttctcctgcg acaaaggcat ctgccacagc ttcttttaag tcagcccaag attgcgcctc
    18961 tttgccgact aatataggga agaaagccac ttgattttgc tctgctgcgg ccaaatctcc
    19021 tggagaatcg ccaaccatca tgaggcgttc tttttgatac cctttttgaa gaagctctgc
    19081 aataacatcc tcttttttac cacagtcttg gcaatacaag tcatcaacat gtgccattaa
    19141 tccttgatcg tgccactctt cttcgacagc ttctttattg gctgaactca caacgaatac
    19201 tttccctagc tgatgcaatt tctcaaggcc tgattcagct cctggaaaag tcaaagcctc
    19261 accttcataa gctttgattt gacggttcac ttcattagac cattccaaag ctttttgaag
    19321 gtcatcactg gcttctttag caagctctgc ttccagtgaa gcattggaga gggatttggt
    19381 gttggcaacc caatctttca aacggtcaat gcctttcaat cctgcatagt caagtcccat
    19441 gacaagccca acaaaacgat taaccccacg cgtgcgtgag tacagattaa catggtccca
    19501 ttcttttaaa aatacttctc tatttgtcac cccaaagacc tctgcagcaa ttggaccaaa
    19561 gaatagctga tgcttatagg tcatcgtatc catcgcacag ccatctgagt ctacgcagaa
    19621 gacaaaggct tcctttttag tcgtcatgtt ttcctccaat caattataat tcatctgatg
    19681 actttattgt aacatagcta gaaaacgctg tcaattagaa aactaacatt aggttcattt
    19741 ttcttaatat cctttatttt aagatgaatt tataaatttt tgccaaattt ttctctctta
    19801 acgatcattc taaagttagc caagtcatca tatcacttat gataatagca actaacctct
    19861 aaacaaaaac tcacccaagg cattacattt tcttgagtga gttagttact aaggattaaa
    19921 cgccagagta agctgcaaag cctccatcaa ttgggagaac aacgccgtta acgaagcttg
    19981 ctgattgttc atcagctagg aagaagagac ctccaatcaa ttcttctgct tcaccaaaac
    20041 gtcccattgg cgtattgtta aggatttttt cagcacgtgc tgttggttgc ccctcttcag
    20101 tgaacaaaag acctcgattt tggttagtca ccaagaagcc tggggcgata gcattacaac
    20161 ggattcccac ttttgagaag tgaacagcta accattgcgt aaagttggaa atagctgcct
    20221 tagctcctga ataagctggg atttttgtca atggtgtgaa agcattcatt gatgaaatgt
    20281 taatgatgtt agcccctttt cgcccaacca tgtcttgagc gaaaacttgc gtaggaagca
    20341 atgttcctag gtagttcaag ttaaagacaa aactaattcc cgcttcatct aaatcaaaga
    20401 aagttttggt ctcttcaggc aaaccaacct catgaaattc attatcagta gtcgcttttg
    20461 gactgtttcc accagctcca ttgaccagaa tgtctgctgg accaaaatca gctaaaacag
    20521 cctgacgtac ctcttctaaa ttctcttttg agaggacatt tgctttgtaa gctttagcca
    20581 caccaccttc tgcttcaatc tcagttacaa aagcttgtgc tgcttcttgg ttcaaatcta
    20641 aaagagctac cttggcacct gctttagcaa actctttggc catgtagccg caaagcacgc
    20701 caccagcacc tgttacaatc acaaccttat ctttaaaatc aattactcta gtcatgttat
    20761 tcctctttct tatttgtcgc caactgtttt gacagtaatg ccaaagtctg gtgtcttacc
    20821 agcagcacgc atattagcct cataaagacc attaaagtaa gtagctccca aagcacggtc
    20881 atataaacca taaccaggtg ttttggtttg atctccccag atacgacgac catggtctgg
    20941 acgaagagcc cctttccaat catagtcaac caataatttg acaacagcat tcatgtcaat
    21001 atcaccagct tgtgacaggt gagctgtttc ttggaagccc caagcgccgg ctgtcacgtt
    21061 ccgcgtgtgc ataaagttga tacggttacg tttaagagcg tactcagtca tggcaatcac
    21121 atcattttta ggatcagaag catacgaccc tacacacatg gtaatcccat tgtttggaga
    21181 atcatagaga ttcaagaagc gctcaacagc atcttgacct gttataatac gtggcaaacc
    21241 aaagatacca tatggtgggt catcagggtg gatcgccatt ttcacaccag ctgcttctgc
    21301 ggttggcata atagctttga tgaagtagtc taggtttacc cataaatctt cttcagagat
    21361 attgttgcgg taattctcga tgatggcttt catttcttcc ttagaataag aagaatccca
    21421 acctggtaga ttcaaatcgt cagctactgg atcaacaccc tctaaatcag cttttaagaa
    21481 agcaagcgat gtggatccgt ccggtagtgg atggttaagg tctgaacgtg tccagtcaaa
    21541 aactggcata aagttgtaac aaaccaccgg aatacctgct ttacccacgt tggtaataga
    21601 ggttttatag ttttcaatca atgcatcacg cgttggcttg ccttgtttga tgtcttcatg
    21661 aactgggata gattcaataa ctgaaatctc taagccagca tcttcgacca ttttcttcaa
    21721 ggcgagaata ttctcaagtg gccaagcttg accaaccggc acatcgtaaa tcgccgtaac
    21781 aattccctgc atgcctggga tggctttgat ttcttctaag ctgactgggt cctgtttacc
    21841 ataccagcga aatgacattt tcatatacaa ttacctagag ctgataggct cctttttcct
    21901 ttcatttcca cacgattttc atttattgag aaggctgcgc ttctctattg atacagtttt
    21961 aattaaaata gcgaacagcg ttgtcgtaag cgatgtcttt agtcatctga ccaatggctt
    22021 gataatcttc tgggacttcc ccttcttcaa tccattctcc aagataagtt gacagaatac
    22081 gtctgaagta atcatggcgt tgataagaca agaaggaacg agaatccgtt aacatgccta
    22141 caaaattagc aagcattcct tgttcagcaa gagcattcat ctggctaatc attccaagtt
    22201 tggtatctgc aaaccaccaa cctgctccaa attgaaggta acttgccaca ccggcttcat
    22261 tggcttggaa attagccaaa gtgttggcta ctgcaatgtt gtaacttggg tttaagttgt
    22321 accagatcat ttttggtagg ctatcagtct gcaccaagtt atccaataaa cggttcatat
    22381 tgctggttaa ggctgtttgg tctcctagag aatccacccc tacatctgct cctaaacgtt
    22441 tgaaaatacc agaatggttg ttgcgcagag caccaaaatg aacttgggtt acaaaaccat
    22501 attgcttgta caatcgacaa aggtctgcaa aaacagcagt ctgccattgg ttgatgtcaa
    22561 gctggcttgg tgtatcaccc gctagcacct gggccataat ctgatttaaa gcttctggtg
    22621 tagccttttc aaaaacaatt tctgcaaagc tgatatcact tgccttgcag cctttttcag
    22681 caaagtaagc aatgcgtttc tccatggctg ccataaacgt cgtaaagtct gtaatgcggc
    22741 tgccagttga agttcctaaa cgctccacaa actgtgcaaa attgcggtgc tctacaaaag
    22801 cctcatctgg tctaaaggtt ggtgctacaa ctgtctcgaa agtgctatcg tccgcaagtt
    22861 gttgatgcca ttcgaggtca tcaagagggt gatcagtagt tccaataaaa gtcaccttgc
    22921 tgtctgcaat taatttgcgc gggctaatct tatggtcaac cagataagca ttcaaacgat
    22981 ggtaaatctc ttccgcattg tcctgcgtca acagctcttc cacaccaaaa acatttttca
    23041 actccatagc tgaccaatga taaacagggt taccgtagga acgttctaag gttcttgcaa
    23101 aagctttaaa tttatcaagt ttagacgctg aaccagtaat ttcttcttct gagatgccat
    23161 tagcacgcat caatcgccac ttgtagtgat ccccgcctaa ccataagtca acaatattgt
    23221 catagacctt atcttcaaaa atttcttttg gatctaagtg acagtgataa tcaaaaatcg
    23281 gttgatcttg aatctgttga tacagttttt tagcagcttc attttttagc ataaagttcg
    23341 catcgttaaa tgtcatgttc gtctcctctg tgataacttc cacacttagt caagggctga
    23401 tacaaatgat tgcgcaatcc gagcgacact gttataaccc tctgtcgcca ccttactagc
    23461 aagggcggaa ccaacaccta cagcgactgc tccagcattt ttccactctt tcacgttatc
    23521 aactgaaacc cctccagaag gcatcaaatc aacctcaggg attggaccgt gaatatcttt
    23581 aataaaacct gggccaacaa cccctcctgg gaaaacctta ataataggac aagaagcatt
    23641 catggcagtc acaatttcag ttgctgtagc gcaacctggg aagtaaagat tgccttcttg
    23701 gttagcaatg tcagcaattt ctttggaaaa atgcggactt actaagaatt tggcacctgc
    23761 tgcaatcgct tcttttgcga gttcagtagt cattaccgta ccagctccaa taacaacact
    23821 tgtgtcatct ttaaagtcat ctgataattt gctaatgacc tcagaagcat ttggagtgga
    23881 gtaagtaatt tcaatattac gaattccacc taaaaccgca tatttagcga tttcaatcgc
    23941 atcttctgcg gtttttccac gcacaacagc gaaaaagtaa ttctctttta attgggttaa
    24001 catccatttt tcctcctcta tgaaaccgtt atcttgttat tatacaaatc gtctgatgac
    24061 ttgtcaagaa aaaagtctaa aaaaaacagc aattatcaca attgctgttt gttcttcgcc
    24121 gatattttat taaggcaaga aagccgttcg ttttacggtc ataatatgta aaagcatagc
    24181 atcatgcgct gcgatagggt ttctctcctt aatagctgtc aaaatgtcgc gatgggcttg
    24241 tagagaatct tctttcatct gacgatttgt gtagttagca tttatcagat gaattgactt
    24301 gttaatgaca ggcaataaac tgtccatcgc aatattacca ctaaatttgg ccatcatcga
    24361 atggaaggtc acatctaact gtaagtgctt aggatcacct gctgttacag cttcttcaat
    24421 ctctacgaca atcttttcaa gctctttaat ctctttcggt gtcgcgttct gagcagctaa
    24481 ggcagcaatc cgaggttcta ataacaaccg taattcaaac aaatctgctg tcaattttgc
    24541 cgtatctttc accaatgaaa aaccaagcgg gtcttctgat accccttttt tagaactcac
    24601 ataggttcca gaaccctgtc tcacttctaa gacattgcgg gttgctaaac ttctgacagc
    24661 ctctcggata gtgctacgtc ctacatccaa gtcttgagct aattcgtact cattagggag
    24721 cttagcccct acgtcatatc cacgttctaa aataagctgt aataaacgtt ctgctgtttt
    24781 ttcaactaat ggtctagcca tcgtatagtc ctcttcctgt ttctactgtc tcctatttta
    24841 cactattttt tcttgtaatt gtagttagga atagctgtcc aacgtttttt aaattctctg
    24901 accacttgtt taggctgacg gttccgcgag aagagtcctt tatggttacc ttgcacacgg
    24961 aaaatcatta aattggtctc aaagtctgca aagttccaaa cttgttcacc aacaaggtta
    25021 ggaatctcat caaaaactcc atgcgtcatc gcataaaaat cacattggaa ttcttccgta
    25081 tacggaatat cccacatcga atgcaagcca ggcaaggtat ctgccccata ctcggtcatc
    25141 aaaatgggtt tgtctgggaa cttgctctgc cattctaaca attccttgcg taggccagct
    25201 tctcccttag ccagatcacc gtgattcaca taccaagcgt aataacggtt caaacaaatc
    25261 acatccacca aatccataac ttcatctcgg tctggtgttg ccataaaaat attgaccaat
    25321 gtcactgggc gtttttgagg gtccaattct ttgtaaagag ccaccagagg ttcaaaatag
    25381 tcatgcgctc ccgcttcatg gcttgcaggt tcattggcca cgacccacat gacaacagat
    25441 gggtgatttt tatcgcgttt caccaattct tggatagcct gttcgtgtgc ttcttttgtt
    25501 tccatcacag accaagttcc catatcttta ggtgttaagt caagggaagc cgtgaaattt
    25561 tggaataaac caaccgctgg gatttcgtca atcaccaaaa tccccatacg gtctgcaagg
    25621 cgcatcattt cttcagagta agggtaatgt gaggtacgga acgaattagc gccaatctct
    25681 ttcaacaagt tcatatccat caagttagcc gcctcattga ggccacgacc attgataaag
    25741 gtatcttcgt gtttgccaaa acctttaaag taaacaagtt tacgattgac aaagaactga
    25801 ccatccgcta catgtacact acgcactcca aaaggttctt cataagtatc aacaatttga
    25861 ccatctacac taatttcaat acgagctgtg taaaggtaag catccagcac ttcccagaga
    25921 tgcacgcaat caagtttgac atggccgtcg ttcgtttgac caacgacttg acgttcttca
    25981 tcaaggatag tcacctgaat cgcatcaaca gccgctgacg tttcaacagc aatggaaagg
    26041 tctgctgttt tcaaatcatc tgataaatca ctggtaatgg tgatatctga aatgtgagtt
    26101 ttaggacgca ccactaattt gactggacga tgaatgcccg catagttaaa gaaatcgaag
    26161 ttttctttga ccactttttt catgctgcca tcttcttgac gttcttcgct ataattaccc
    26221 acaggaagtg tactgtaatc taaaatatta ttggcacgga cagaaattct gatctgatgg
    26281 tcctggtaaa gttcctctgg caccacgact tcaaaaggag taaatcctcc cttatgagaa
    26341 gccagctcac gcccattaac atacacgata gcattgtgag tcactgagcc aaaacgtaag
    26401 accaattcat catctttagc taactttgga agatcaacca aacgctcata ccaaaaatca
    26461 ccgatataat tgcgtttatc cttatcgacc accacatcat taaaagaagt cggcacaacc
    26521 ataacgtctt ctgttgacaa acagtcttct gggttatggt ctcctaattt gaattgccac
    26581 aaaccactaa ggtcatataa acttcttgtt ttggttaaag ttgggtatag catctttttc
    26641 tcctttttct cattgttaac gtttaatctc atacgatgca tcagttatta aataatcaat
    26701 atctgctggg gtaataatat tgctgtcgcc ctcaatcgta tgcttgaatt taaaactcgc
    26761 cattgcaata gctaaggcct tgtcaggcgc ttcattttgt agcatgccat gaatcaagcc
    26821 agcagtgaaa gcatctccag taccaacacg gtccaacacc tgaatgccag acttgtctgt
    26881 ctggtaaaga ttaccatctt gatataaata acccttcaag aggtattcat tggtatgccc
    26941 catttccctt tgggtaaaag caaagctagt cacaccgtaa gtttttgcca acttagaaag
    27001 aacgttttcc aataatgctt gatcttcata cggtcgactc aatcccaatt ggtctttcaa
    27061 atctttttcc ccatcgcctg ctaaaaccaa gggttcaatt ccaatacaaa catctgccaa
    27121 agcaactaaa ggggacaata attctctagc ctcttgaaaa gagtcccaaa ggctggccct
    27181 aaagtttaaa tcaaaggaaa cctttaatcc ttctgttttt gcctttgtca tcagataatg
    27241 ggtcaagtga taaagattat cggtcagagc cggggtaata ccagacacat gaaaccaatc
    27301 agcccccgca aaaacatctt ctaactcata atcagctaac tgcgattccc aaaaagcaga
    27361 atattttcgg tcataggtca cgcgactagc ccgtaaggaa aacccttttt gatagtaata
    27421 aatccccaaa cgttgacctt tttcaataat ataatcttga ctgatttgac gagaaaaaag
    27481 aaaggttttt gtcattcgtc ccaaatcatt ggctggtatt gctgagataa gagagacttt
    27541 atgccctaac tgcgctaacg ttgacaaaac atttaattcc gacccaccaa attgacattc
    27601 cagactggtt gcctgagtta gggtctggta ctgcggcggt gataatcgta acaaaatttc
    27661 gcctaaagaa acaacttttt tcactcaaaa cctcctctac taatgatgat aaggacatta
    27721 tacctgattg tagtgatttt ttaaaaacct aggcaaagag tcctccgatg actaaaaatt
    27781 actttttctc taagttaaaa gagttgagca catcttgccc aactccttcc aaacgactaa
    27841 tctttatcaa ctggatattt cgttacatca acgtagtcca tatctgacaa tggcacattg
    27901 cgagcgatat ccttcacgcg ttcttttgaa cttgcagctt tcatgacttg aattttctct
    27961 tggatacgaa ccatttcttc tttatccagt ttgtagaatc tcatcaagaa caaggcgact
    28021 gacaaggcga caaacggaat accaactaaa agaataatgg ttgccatttt aagttctggt
    28081 gttaaaggtg tttccattgt tgggaaagct ttggcaaaac caatcgttgc aagaacagct
    28141 ccaacaacca tcggtgcaaa tgaagaggcg atagagtctg tcaatgagaa gattgttcca
    28201 atcatccctg acacataacg acctgattca gatgtttcat agtctgaaat atctgccccc
    28261 attgttaaca ccaaaccagc cggcgcttga gtaatgtaac gagccaacat gtaagtaatg
    28321 ataaagcaga tagtgtaaag gttaatgtta cttaaactca aatcaccaac tttaccaaag
    28381 taaaggacaa ccccaaaggc agccaaggcg atcaaaccaa attgaagtga cgccacatat
    28441 gagaaacgaa gacctttttt acgagcaaca cttgaaatca aaatgttaat caaaacacct
    28501 ggaatcacaa aaagtagtga gaattgacct gacaaggcat agttaccaaa cataataccg
    28561 taaagcataa ccatgacaac tgagtctcca aagaattgca cgctaaactt aacgagtgct
    28621 gctgcaattg acaagacttg aagaggtttg ttgcctttaa tgactttcat gtagtctttt
    28681 aattctgttt tttgcgtatt ttcaccaaga ccgaagtatt ctttgttgtc tttagaccag
    28741 ataccgataa cagccaataa tcctaaaata gctgaaataa cgattgttcc atagataagc
    28801 acattgaaga attccaacgt gaagttgcca aatttaggaa ccaagaatcc tgaaaccaca
    28861 aactgtccac cagtcatcaa ggttgttaac atgacggcat ccacaatgtt gaaaattgga
    28921 cgttgttttg gatcattcgt caaggcagtt tgacctgctt ttgtgatggt ttgttgcatg
    28981 gaataaccaa ttttgtgaac aatcaatacc aaaataaaga gtgggaagcg catcccttcg
    29041 ctaacattat ttaaagcaag taatagaata agcgatagag ccgtaataat attaccagca
    29101 attaaaattg ggcggtattt cccaaactta gtatctgttt tatcaatcat gataccgata
    29161 gctgggtcaa taaaaccatc aaagatacga atataaccca tgatttggct aacaaagata
    29221 gctgctagcc caagaacacc tgttgaaaaa taggtaataa acatgaaagc aaataggtaa
    29281 atgttggtag atgtattgtt taacgcaaac aatacaagtt gccaaacttt agctcggtta
    29341 taggtaactt cctcaaccct ttgatcaatc gttttctcca ttagagaccc ccttatatcc
    29401 taacacttca attgaaagcg tttttatttt ttacatgttt atcttactat tcatctgatg
    29461 atttgtcaac ccaattttaa tttttttccc tattttttta aaaataaggc tattttagag
    29521 atttaaaaga aaaatcatct gataactaat gcgtctttag tactaatcat cagacaatta
    29581 aacgcttatg agtaaaaatg acgcgttagc gatttctttt accaaacctc ttcagcaaac
    29641 tgccacttct gttggggcat tcttttctaa aaagaaccag cacaacctct gcttattctt
    29701 catcaactta tcagccaaag aaattcttcc atgaggtcag agtaccaaaa aaagagaagc
    29761 gttagcttct ctttagtctt cgattaattg aatatctgcc cctagtgctg ttaattttgc
    29821 aatgatacta gcatagccac gtaagataaa ttcaatatta gtaatttctg tcttgccttc
    29881 agccattaga ccagcagtca ctagagccgc tccggcacgt aaatcagtgg ctttgacctg
    29941 agctcctgtc aggcgagacg gcccttgata aacaatctga ccaccaataa ctgagatatc
    30001 tgctcccatg cgcatcaact ctggcacatg gttaatgcgc ttttcatata tagtgtcaat
    30061 aatcgttcca cgaccatctg cttttaacaa caagggcgtt aatggctgtt gcaaatcagt
    30121 ggcaaagcca gggtaaggag aggttttaat tgtaatagcc ttgagggatt cttgcttttc
    30181 aacaaagata gcatcctctt ctaccgtcat acggacaccc atttcttcta acttagcaat
    30241 gaaactctct aaatgctcat aaagaacatt agtgatctta acaccttttc caatagctgc
    30301 cgccaaagcg atataagtcc ctgcttcaat acgatcagga ataacttggt gtctagtacc
    30361 atgcaatttc tgaacacctt gtatcgtaat aatatctgta cctgctccac gaatatgcgc
    30421 acccatgtta ttcaaaagag tagccacatc aataatctct ggctcacgtg cagcgttttc
    30481 aataaccgtt ttaccttgag cttttgttgc cgcaaccata gtattaattg tagcaccgac
    30541 actaacggtg tccatataga tatgagcgcc atgaattttt tgaccatttg tcgataaatt
    30601 catattttca ccctcataag acacttcaac tcccatagcc tcgaaggcct tcaaatgcaa
    30661 gtcaattggt cttggtccta aatcgcaacc accaggtaag ccaacaactg cttgtccaaa
    30721 acgacctaaa agactaccgt aaaaataata ggaagctcga aggctattaa tctttccgta
    30781 aggcatcggg atgtcttgca cccctctagg gtcaatttct aaagtatcac catgatagtt
    30841 tactgttgct cccataagct ccatgatttc aatcagacta tctacatcac taatagcagg
    30901 tacaccatca agaatcacaa tatcatcggc taagatgatt gctggaataa gcgcaacaac
    30961 actgtttttt gctcctgaaa ctgtcacttc tccagataag gcttttccgc cattaataat
    31021 aattttacgc atacattcaa aactttctta tactagaatt caaccttttc attttatcat
    31081 aaatcatgaa gcctgacaat tattgacgtc ttaattttta atcatccctt ttaaaggctt
    31141 atttaataac aaaaaagcag agtaagattt tttcactcac tctacttttt taataaagtt
    31201 gtcgtttata atactgtttt tacagcttct actaaagcat caaccttatt taaacgctcc
    31261 catggcaaat caatatctgt tctccccatg tgaccatagg cagctgtttg tttgtaaatc
    31321 gggcgtttta aatcaagcat ttgaataatg cctgctggcc gtaaatcaaa gacttgacga
    31381 acagcagctt ctaaaacagc ttcaggaacc gttgaggttc caaatgtatc cacgcgaaca
    31441 gacacaggct gagccacccc aatcgcataa gctagttgga cttcagcttt ggtcgcaagg
    31501 cctgctgcca caaggttttt agcaatataa cgagcagcgt aagaagccga acggtccact
    31561 tttgtcgcat cttttcctga aaaagcaccg ccaccatgac gtgaatagcc tccataggta
    31621 tccacaataa tcttacgtcc ggtcaatcca gagtctcctt gcggacctcc aataacaaaa
    31681 cgtcctgttg gattaatgaa gaactttgtg tcatcatcta aataatctgc tggaattaca
    31741 gccttgatta ctttttcaat cacatcctga cgaatttggt cattagtagc ttctggatca
    31801 tgctgagtag aaataacgac tgtatccaca cgaacaggtt tatcgtgttc atcgtactca
    31861 actgtcactt gagatttagc atctggacgt agataactaa tctcacctga cttacgtaat
    31921 tccgccaagc gacgcactaa ttggtgagat aaggaaattg gtaaaggcat caattctggt
    31981 gtttcattga tggcaaaacc aaacatgagc ccttggtcac ccgctccaat atggctaagg
    32041 tcatcagtat caccttctct gctttcgaga gcttcattaa ccccctgagc gatatctcca
    32101 gattgttcta caagtgatgg atgtactccc actgattctg ctgaaaagcc atattctgct
    32161 tctgtataac caatttctgc aatggtgtcg cggaccacac ggttaatatc aatgtatgct
    32221 gttgttgaga tttctccaaa aacatgaaca gaacctgtgt aaacacaagt ttctgcagcc
    32281 acatgggctt ctggatcttc tgctaaaatg gcatctaaaa tagcatctga aatttggtct
    32341 gcaatcttat ctggatgccc ttcagatacg gactcagacg tgaaaagttt acgttctgac
    32401 ataaaaatgt cccccctaat atgttgattc ttcctttttc agtcacattg accacaaagc
    32461 aagaagttgc ctaccccttt cttcctagct gattgagcaa gtcaagtggc caaaaccaac
    32521 ttagctaatc agttacggtt ttactagtaa ggcaactagc tagtccacct agtggctagc
    32581 gtccattaac cagacaaaga atgtctgaca atagcgttga gttacaaaga atccggtctc
    32641 cttgttgaga ggatgtcacc acaaaataag ccttagacga agtaatttag ctaaagagag
    32701 aacgactgtt ccccaaatga agtcaacaac gtctcaaaac atttcgttca acagaccgtc
    32761 ttatcgggac tcaataacaa tctattataa catgttttag ccatttaggt gccattcttt
    32821 tcactcatta tcctatttat ttcaaaaaaa cctcaaggtt attcttgagg ttttcttgat
    32881 agtcaacaat ggtgtcatta agacgattca gttggatcgg gttattctta gattagttta
    32941 gtcagcatgg ttttgctcat ctttagcttc attttcatcc tcatgttcat ggtcgtgatc
    33001 atctttgtct ctgtgctcgt gagcatgacc ttcttcatct tcataggcat gattatggtt
    33061 gtagtcatgt gattccgatg cttcttgagc actttctttc gccttagtag ccatagctgc
    33121 tttttcttca gctgttccat tacctaccat agaaccttcg taaaccgctg ggaagttttt
    33181 cgcaatggct tctggaatat gttgctcgtt caatttaagg tctgccaatg ggatattgtt
    33241 atgactaata tcaatgttag taactgtctt attgggttta gataggttga catttgttaa
    33301 ttggttttta gacacgctta aaatgtcaag tgctgtaaaa ttattaacac cttctagaga
    33361 agtcaactgg ttgcctgtca catccaagaa agtaagtgac ccttgcttgt ctttaagcac
    33421 aagcgattta atttggttac cttctgcttc tactctgaca atgacgctac ttgcttcaat
    33481 accttcaaga gattgcaatt gcgcacggtt aatagatagg ctagatagat taggattatt
    33541 tttcaagaaa tccaaatgag aaaccttggt atcattgacc attaacgttt ctaatttggg
    33601 tgcttgaagt gttgctaagt caacatcagc atttcttgat aaatcaacaa ccgtcaatga
    33661 ttctttatga gaaacagggc ttaaatctgt aatctgatta ttatcaatgt gcaattcttg
    33721 caattgatgt aacgatgcca gtgggcttaa atcagaaatc ttattattac tcaatacgag
    33781 gaatttgaga tttggtaatt gaccaagcgg cctaatatct tcaataccat tatcagcagc
    33841 cgctactagg gttaagtttt tatatttgct caagaaacta atatctttga gattgttttg
    33901 tgaaatatca atgccttcta actgtggcat attatccaaa aatctataat cagtcacccc
    33961 tgtttttgtc attaacaact gtttcaattt tttaaattgc aaaacaggtg agatgtcttt
    34021 gattggtgta aagccaattc ctaaagtttc taagttgggt aacagtgaaa gtcctttacg
    34081 ttgcaaagga tctttacggc tgcccaagtc aagtttgata accgttgcta accattcttt
    34141 catcttattc agatcttttt catttgatgg gaatggggtt ggagcatcgt gagtgcgaac
    34201 gatatccaaa atcacttctt catcaaaccc taaggcacgc aaggtatcca ttccaacctt
    34261 atgtttttcc aattcacggg catgctcaat agcatgtgga tctggaatgt cttttccgat
    34321 ttcaatatca gataacatca atacgtgtgc gtggtcatgg tgaggatatt ccaaaccaag
    34381 tttaccgtct tgtgtttcca cacgtttaat agttgatgga tcaatcccca atttttctgc
    34441 caaataagct aatttttctt ggtatccctt ttcacgttca gatagctctg gtgtgtgatg
    34501 ggtttctgct ggcttttctg cttttttagc gggatcgtat tgatctgcca catgtgccca
    34561 gccaccctga cgaaggtccg caaaagaaat aggatgtaag tgaccatcgt ggttcactaa
    34621 aatactggct tttgttaccc caacaatacc ttgaccgtta aattgaaaac catctgaggt
    34681 tgggaaatgc aagcctggaa taccattagc tgtaactgtt gaaacagggc tactggtttg
    34741 tggcaagcga gtagcaacct gtttagcttg tgcctgtgtc tgacctgata agcttgactt
    34801 caaaatataa tggaagtgat catcgtggcg aaccgtgtag cctaaagcat cttcagccac
    34861 aatatctgct gggttaaatt cataatggtg atgaggatct gctactttag aagtcccttg
    34921 actagctgct tgctgagcaa cagctggctt agctaaactt gctccttttg gaataaggta
    34981 ttcaaatgga cttcccttta aatcggcata aaaaataaaa tgcgaatgac catcatggtc
    35041 aacaacgatt ccctgatctg tttttgataa gatttttgag tctttggtta aaataaaccc
    35101 atcatctgta ggaaaatcga cacccgccac acctttgtga gtcttgttta tctttttgct
    35161 ttttttaatc ggtttaattt tgtttgacgt cattccctta cgtgattgtt tcgttttaat
    35221 gggatatgta ccattacctc gtgattgaca agctatcaaa gtcaactgag atgataacaa
    35281 tagaccaact aaaataataa cttttttcgt tttcattcaa ccctcctttt tatttaactg
    35341 gttaagtata tcacatcact tgtttttcct caagctcttt ttaggataac tattagttgt
    35401 tgacgagttg gagctctgaa gcttcaacaa acaatagttt ctgttgttag tagcattaca
    35461 caaaaaaact aacttttctt ttcctttgaa aataagatct tttataatat actatacata
    35521 tgaaaacatc agaaaaaatt tatcaattac tgtcacaaac cgatgacttc gtcagtgggg
    35581 aatatctagc agatcaactc agtatctctc gtacatccgt ttggaaatcc atcaaaagtc
    35641 tcgaaaatca ggggattcaa attgattctt taaaacacaa gggctaccgc atggtacaag
    35701 gtgatatttt attacccaaa accattagcc aagggcttgg gatgccagtc acctataccc
    35761 ctcacagcca atctacccaa ttagatgcca aacaaggaat cgaagctcat aacagcgctc
    35821 caaggcttta cctagctcct agccaagaag ctgccaaagg acgcctcgat cggcaatttt
    35881 tttcagctag caccggtggt atttacatgt ccatgtacct aaaacccaat gtcccttata
    35941 ctgatatgcc tccttatacg atgatggttg cttccagtat tgtcaaagct atctcgcgat
    36001 taacaggcat tgatacagaa atcaaatggg taaacgacat ctatctaggt aaccataaag
    36061 ttgcagggat tctgacagaa gccattactt ctgttgaaac tggtttaatc accgatgtca
    36121 ttattggggt tggtctcaac ttttttgtca ccgacttccc agaagcgatt gctcaaaagg
    36181 caggttctct ctttaccgaa aaaccgacta tcacgcgcaa tgaccttatc attgacatct
    36241 ggaaattatt cttatctatt cctgtcaagg accatgtcaa agtttacaaa gaaaaatcac
    36301 ttgttcttaa taaacaagtg acctttatag aaaatagtca agaaaaacgt gctattgcga
    36361 ttgatctcac agatcaagga cacctcattg tacagtttga aaatggtgac cttcaaacct
    36421 tgcgaagcgg tgaaatcagt ctttcttctt gggagaatta gccgttttta aaatggtttt
    36481 agtcaattgg ttaatggtat gcactcttct taaatcccta aagagcaaca agccccaaaa
    36541 taaggcgaag agataatttc cagagagcaa caggtcatta aaaaaatagg tttcaaaggc
    36601 acatacaaag gccataaaaa gaaattgtcg aatagtcata gctttattat aacaaaaaaa
    36661 tactgtacta tgaagaaaag taacgagata aaacgtgggt aagggcaaaa ccttaccctt
    36721 atgtatttca gttttagtcg tcaatagtat ttattttatc gagcaaaaaa tcaaaccctt
    36781 ctggaatatc aagcgctact tcttgttctt cttgaacact gtctttttgt gatttcattt
    36841 gctgagcaaa ttccttacga atatgctgaa aatctgtcct tggtactgcc agaatattgg
    36901 gagaaaaacc agcagcttta ctcataatgt taccaaacat atcattaaga ttatttcggc
    36961 tcatgacttg ttctgcatta aaggcagcct cgaaagccaa aatcgcattc tcactatttg
    37021 ctaagacagg ctcagagccc atcaataagg ctctgtcttg ggcagaaatg ttatctagaa
    37081 tttcattcca agcatttttt agagcatcta gatattgtcg agattgttgg ctatttcgaa
    37141 ccgtttcttc catgattttc aaaatggtaa cccgatcaac cctgtagctt gcggttttag
    37201 gtttcgtttt atcagatctt gccagtgaat caggacgcga ttggagctgc gacaattgtt
    37261 gtttaagttg tgccaactca tttttgagcg tttcaatctc tgagattaac tctcctgaca
    37321 agtttgcttg ggacaaaatc tgctctttct gagctaattg gatggtcatc atttcggcat
    37381 aaatccgagg atgggttccc tttttgattt cagggagatg actagtaaca actgttatca
    37441 tttggaatat acgatctatc gagagagaca aattggtatc aaaaacagct gactgacgct
    37501 gattgtcgcc gccagcttta accaccaata aatcacgcag ataggtcaat aaatctgtcg
    37561 caaagcggct catgctcttc ccactatcat aaatggtctc taaggctgcc agagcttgcg
    37621 tagcctgttc ttgggagaca tatcgaacat agtcacccag agcaagcatg gaaatagaac
    37681 ctgtaatttc ttcggcaatt gcaatggtga cctgattatc tggtgacaag ctcaaagcct
    37741 gatctaaaat agataaagca tcacgcatgc ctccttctgc tcgccttgca atgagattta
    37801 aagcatccac ctcataggca ataccttctt tgtccaaaac ccaggctaaa tgctctcgaa
    37861 tagctttttg cttaatagct ttgaattcaa agcgttgcac acgagataaa atagtggctg
    37921 gaattttatg caattccgtt gttgccaaga taaagacaac attttctgtc ggttcttcca
    37981 aagttttcaa aagcgcatta aaagcccctg ttgataacat gtgaacctca tcaataatat
    38041 aaaccttgta agtcgcacga cttggcgcat aggttgattt gtctcgaatg tcacgaattt
    38101 catcaacacc attattcgag gcagcatcaa tttcaatcac atcttccaag cttccattcg
    38161 tgatatctcg gcaaatatcg cattgattac agggttcacc atcgacttgg ttaggacaat
    38221 tcatggcctt tgcaaaaatc tttgccgcac ttgttttccc agtccctcta ggacctgaaa
    38281 ataaataagc atggctaatc ttgccagatt caactgcctg ctttaaagtt gtggaaataa
    38341 ccgattgtcc caccatttcg tcaaacgttt ggctccggta tttccgataa agagcttgat
    38401 acatcagttt ttaactccaa acatgttaaa ggtaaacgtg gtcttttcaa gaaataggtc
    38461 cacaaaggcc tctaagtatt cttgatcaac ctcatcataa tcagctacaa ggctagaatc
    38521 caagtccagc accccaatca aatggccttc tttcaccata ggcacaacaa tttcactcat
    38581 ggctgccgca tcacaggaaa tatagttggc atgctgcttc acatcattta taataatggt
    38641 tcgacgagac tgagctgatt cgccacaaac acctttacca agcttgatat ggacgcaaga
    38701 aaccctacct tgaaaagggc caagaattaa ttcctgccca tcaaaaaggt aaaatcccgc
    38761 aaaaacagaa ttgggtagtg tcatgtttaa cagggcgctg gcatttgaca aattagccaa
    38821 agtatttgat tcattcgcaa acagctcttt tgcctgcgct atcattagtt ggtattgctc
    38881 aattttttta gacttattca taccttttat tatagcatat ctgggtctat tcgagtattt
    38941 tttacgacta tctttcgctt cagtcagttt ttaaaatggt ttttgaggtt gtttatgata
    39001 taattttcaa tattattaat atcatcttaa tattaggagg ttttcgtgaa acaaatcact
    39061 caacagaaat ggttacgata cggtcttttt attgctttag ttttaaatgg tattgaactt
    39121 gaattgttag gactgactgc taacaacctt tcctttaaag aagcttttgc tctaatacta
    39181 accattagtc tattaggcat ttacttaatt ccatttgcag cagctatttt ttatttaagt
    39241 aaaaaatttc atatgaacct gaacgttatt attgttagct gtcttagcgg actttatatt
    39301 tcaggttttt tagcttcttg tgggaaccat ctcgtaggac aattttggtc atacatcatc
    39361 ccttctaaag acgctttaaa gctttgggga gatgctttaa ctgcccctat tgtcgaagag
    39421 cccattaagg cttcttcggc tattttagta attactttat ttcctagact tactcttaaa
    39481 gaaaaattag ttgttgcttt actttctggc atgggttttc aactaacaga agatatccgt
    39541 tatttgattc aagcaaaatc tatagatagt ctcgtaccga ctgctattga acgtattagc
    39601 actgctgtga cttcacattg ggtacataca gctattttta ccattggagc atacttatta
    39661 ttaaagggtt ctaacctttt ttcaaaacag caacaaattt tctggttatt aagtcctctg
    39721 gtgctacatt tcatctggaa ctctcctcta acaagcattc ctggcatgac agttttacta
    39781 ggaacattaa tccttttaat ctttggtgat ctttttcaaa aaatcaacac ccttgacgat
    39841 gatgtgcttt tttaaactat aaaagagcct tgactaaata atactgatta agggtctttt
    39901 aagtgactca cttcataaag atataagtta ctagtaatgt caacaaaata ctagtatacc
    39961 aagtgatgac aaagtaccac tttctggttt tatggtggta ctttttagct gcaagtaatg
    40021 ctccaaaacc tccaaacaaa actgttatca ctaataagtt tctttcacta atacgccgtt
    40081 tcttttttat ggcttttctt ttatcaaagg catatatgac aaacacgagt tcattccaaa
    40141 caaatagtaa tccaagccaa attaataaca tttctatttt atgatccctt tctctatgaa
    40201 gagcacaaca ataaaagagc agatttaaat aatctactca gccacttcca ctatacttct
    40261 ccaagaatac tcgcaatttt actattaata acatcaatag caacgacatt actaactccc
    40321 tctggaataa caatatcagc atagcgttta cttggctcaa taaactgatg atacataggc
    40381 tttaccacgc ttgtgtactg atcaataata ctttctaagc ttctgccacg ttccatcatg
    40441 tcacgcttaa tacgacgaat aatacgaata tcgtcatctg tgtctacaaa gagcttgata
    40501 tccatcaaat ctcgcaaacg ctcatcttct aggacaagaa taccttcaac aataataaca
    40561 tcctgaggat cctgacgaaa ggtcgtatta ctgcgggtat gctttttgta atcatagata
    40621 ggaatatcta caggtctacc agctaataat tcttttagtt gctgaatcat aaaatctgta
    40681 tcaaaagcta gaggatggtc ataattggtt ttgacccttt cttcaaaact catgtgagac
    40741 tgatctttat agtaagaatc gtgttgaatc attgcaatac gagcatttgg aaaactgtcc
    40801 aaaatagcgc gtgacacact tgttttaccg ccacctgaac caccagttac accaataata
    40861 atcggttttt taagcatttt aaactccaaa tctaaaaagt ctttctcact attttaccaa
    40921 aattgagact ataatgctat aatgaatata gaaacaatag taaaaggaag acgcatgatc
    40981 actaaatttc cccctcaatg gcaagaaaaa cttgaccaag ttgcatttac ccatttaacg
    41041 ccaatccaag aacaggcctt tcaacctatt gttgatggta aaaatttcct tggtattagc
    41101 cctactggga cgggcaagac cttagcttat gtctttccta gtctattggc actgacgcct
    41161 aaaaagtccc aacaactact cattttagcc cctaataccg aattagctgg ccaaattttt
    41221 gaagtcacaa aggattgggc acagccacta ggcttaacgg cacaactctt tatttctgga
    41281 accagtcaaa aacgtcaaat cgaacgcctc aaaaaaggtc ctgaaatcct gattggaacc
    41341 cctggacgca tttttgaact cattaaattg aaaaaaatca aaatgatgtc agtcaatacc
    41401 attatactag acgaatatga tgaattattg agcgactctc agtatgattt tgtccaaaga
    41461 atcagccgct atgttcctcg agatcatcaa atggtataca tgagtgctac taataaggtg
    41521 gatcaaactt ccttagctcc aaatacattc tgcatcgatc tttcagagca aaccaacgat
    41581 gctattcagc atttttacct catggttgac aagcgcgaac gtaccgattt attacgaaaa
    41641 tttgctaata ttcctcattt tagagctttg gtctttttca acagtttatc tgatttgggt
    41701 gctacggaag aacgtctcca atataatgga gctgctgcgg tttccttagc gagtgacatc
    41761 aatgtcaaat tccgtaaaac cattctcgaa aaattcaaat cccaccaact ctccttattg
    41821 ttagctacgg atcttgttgc tcggggcatt gatattgata atcttgacta tgtcattcat
    41881 tttgatgttg ctcgtgataa ggaaaattac actcacagag ctggacgaac cggccgtatg
    41941 ggaaaatctg gtatcgttat tacctttgtt agccaccctg aagacctcaa aaaattgaaa
    42001 aaatttgcta aagtctctga aatcgccctc aaaaatcaac aacttcattt catcaactag
    42061 ttgttaaaaa acaaaactta atcaagggct actaaaaaca acaatccaat tacttcaaaa
    42121 gtaattggat tgtttagtat atcaattcta aagaaacata acgatattac ttactgatgc
    42181 gcatagagtt ctgatacagt cacacattcg tatccttctg cttttagata ttccataact
    42241 gtcggcaaag cattgatagt tgtttgatga atatcatgca ttaaaacaac tcctcccggt
    42301 tgcaattggt ttttgacatt agtcataatg ccatcagtgc tatgattttc ccaatctctt
    42361 gtatcaaccg tccaaagcat ttgtgttaat cctgaggatt gctgaacagt tgcatttgta
    42421 gctccgtatg gagggcgtaa atagcgaggt ttcttgccac aagctttttc aatagcctgg
    42481 ttcgtcatat taacttgatg ttgaatctcg ctgactgaaa gattagtcag attgggatga
    42541 tcccaagtat gattagcaat ttcatggcca gcgtcgctaa cacgtttagt aaggttttca
    42601 ttattcacaa cttttgaacc tatcataaag aaagttccct tagcctggta ttttgccaaa
    42661 atatctaaaa cttgaggagt tgtcgtcgga tctggaccat catcgaacgt taatgcaact
    42721 agttttttgg gatgctgttc tttgtaggtc ctataattat catacgcagc tctatcgcta
    42781 tttgctaaaa aatctggatt aataacatca aataatgtcg tcaaaggtat cgttagcttt
    42841 ttatcaaaaa taaggtttcc cgatttcacc tcaaagccat cgcttaataa agaattagat
    42901 tcttttaagc cattgtactt atcgctatta aaaccagcat ttggatattt tttttcaact
    42961 tcttcttgta ttctttctaa atgtcctgat actagatcct ttacctgaaa cggtttcaag
    43021 tcgtctgtaa cgtgatatgt acttataact ttttctgatt ttttagccaa atgaaaaaat
    43081 tttttctgat aaactatttt agaaatagtc aaagtgttaa ctgatcttag gtgagaagat
    43141 tgcagtttag gctttactaa aatcaattct ttatctgaat tctttttttt gtataatgaa
    43201 acaggtaaat tatctacaaa aaaatcatct gcttgtttta tcggggaaaa ataataatag
    43261 tctttttgat cttttttaat atgttttaca gctttgatca ctaaatctga cgtgtttttt
    43321 ttcttttcag ccaaaactat acgctgacta tcttcgttta gtttccaacg attaataaac
    43381 gcaatagcta aactcaacat cagaatgctt aataaaccaa caagaataac atttaatttt
    43441 ttcaatagtt gcctccatct gtatagacta ttgtaacaaa aaacattaaa aaaataaaca
    43501 aaaagttaag ttaacctaac tttttgttta ttttttttat tactggatat caaatacaac
    43561 agatttaaca gttgtcatag cttcgataga atatttaact ccttgtaccc ctgcacctga
    43621 ttttttagcg cctaagaatg ggaaattatc tgttccacgt tgtgttttat tgttaaggtg
    43681 aacagttcca acttctaatt gctcagcaat gccaaaagct tttgggaaat tagttgtaaa
    43741 aatagaagct tgcaaaccat attcagactc attagaaatc ttgatggctt cttctacagt
    43801 ggttacacga ataattggta atactgggcc gaacggctct tcccatgcca aacgcatgtc
    43861 agttgtcaca tgatcaaaga gaacgggtga aataagattg ccttcacgat taaaggctgt
    43921 caaagcagta gctcccttat cagttgcatc tttaatcaac ccttcaacaa aatcagcagc
    43981 tgatgtatca attaatggtg taatatcagc atcgtcttca ggcattccga cacttagctt
    44041 ttcaacaagg gttttaatct cagccgccaa ttgatccgcc accttgtcca tcacaagaac
    44101 gcgtttaacc gctgtacaac gttgtcctga gtaaccaaaa gcaccggcta caatattttt
    44161 cgctgctaaa gcaagatctg catcttccaa aacgatagca gaatccttac cgccaagctc
    44221 aagcataatt ggtcgcatac ccgctaattt accgattcct tccccaattg gagtagaacc
    44281 tgtaaagttg ataaagttaa ccgcttcgtg ctcaacgata taatcaccga taacagaacc
    44341 tcgccctgta atggtattaa agacacctgc tggaatacca gcttctgcaa aagcttctgc
    44401 tagtaacaaa ccagaaatag agccttgtgt tggtggttta agagcaacaa catttcctgc
    44461 aataagagct ggagcaattt tagaacctgc caagttaacg ggataattaa aaggtgagat
    44521 ggcaagaact aaaccaactg gttcacgacg aacaatagca atcttcttct tacttgcagc
    44581 ttcgaagcta ccaccttcaa gaacttcacc ttccatacga agcccttctt ctgctgcata
    44641 attaatgatt tcagcggtac gaataacttc actgacagct gccttgtgac ctttggctac
    44701 ttcttttgaa agaatcgcgc cgatcttttc agcatcacgt actaaaatat cagccgcttt
    44761 atgaaggtaa gctgcacgtt ccacataaga caaggcgcgc caatctgata gagccttttt
    44821 agctgaagcg taaacagcat ctacctctgc ctgcgtcatc gctggaactg atcctaactc
    44881 ttcacctgtt gctggtgcgt aaatggtaat ctcgttttct gatagtttcc attcaccgtt
    44941 cactaaattt ttatattgtt ttgccaacgt tttatctcct tttatggtag taatcttatt
    45001 ctatcacttt tccgatataa ttcaagattt ggctacatta aatatctgaa aattctgata
    45061 attatttgat aactcaaatg atttcacacc aaaaagtaat tgtattttta gctagcaaaa
    45121 aagagctggt ttaaaccaac tctttaaccc tttaatcttc agaaacgtat tctttagaaa
    45181 gttcaagaac ttcttctgct gttgaacatt ctgtaagcgc acgatttgca tattcttcca
    45241 tcttagcaga gtcaagtttc ttcattaaac tacgcgtacg aagtactgaa gttgctgaca
    45301 tagaaaactc atccaagccc attccgacaa gaagtggaac agcttgttgg tcacctgcca
    45361 tctcaccaca catacctgcc catttacctt cagcgtgcgc tgctttgatc acattgttga
    45421 tcaaacgtaa tattgatggg ttgtatggtt ggtaaaggta tgatacttgt tcgttcatac
    45481 ggtctgctgc catagtgtat tggataaggt cgtttgttcc aattgagaag aaatcaactt
    45541 ccttagcaaa ttggtctgca agcatagcag ctgcaggaat ctcaatcatg ataccaactt
    45601 ggatgtcatc agcaaccgca acgccttctg caagcaagtt tgctttttct tcgtcaaaga
    45661 ctgcttttgc agcacggaat tctttaagaa gtgctaccat tgggaacatg atacgaagtt
    45721 gtccgtgaac agaggcgcga agaagcgcac gcatttgtgt gcggaacatg gcatccccag
    45781 tttcagagat tgagatacga agagcacgga aaccgaggaa tgggttcatt tcttttggaa
    45841 ggtcaaagta aggaagttcc ttatctccac caatatccat tgtacgaacc acaacaggtt
    45901 tgccattcat gccttcaagc actgccttgt aagcttcgta ttgttcgtct tcagttggga
    45961 agtcttgaga atccatgtac aagaactcag tacggtaaag gccaacagct tcagcaccat
    46021 tgtcattaac accttcaacg tctttaggcg taccgatatt agcagccaat tcaaagtgtt
    46081 tgccatcagc tgtttcagtg tgcgcatctt taaggagaga ccactctgct ttttgtttgg
    46141 cataagccgc accagcttct ttaaaagcaa gtacttgatc ttcgcttgga tcgataatca
    46201 cttcaccagt gataccatta acggcaatca catcaccatc tttaacacgt tttgtaatat
    46261 catttgttcc aagtaccgca gcgatctcaa gtgtacgtgc catgatagct gagtgacttg
    46321 tacgaccacc gatatttgta acaaatgctt ttacaaattg tttgttaagt tgagcagtat
    46381 ctgaaggtgt caaatcgtgt gcgataacga ttgattcttc attgattgta gctggatttg
    46441 gaagttttac acctaaaagg tgagccaaca cacgttttgc aacgtcgcgg atgtccgctg
    46501 cacgttcttg catgtatggg ttatcttcca tgccttcaaa gatggtgatg aacatgtcag
    46561 tcacttcttt aagacctgtt tctgcattcg tttgttttgc gcgaatcgtt tctttaacct
    46621 ggctgatcat ttctggatca gcaagaacca tcaaatgggc atcaaaaacg gctgctgctt
    46681 cttcacctaa gctttctact gcattttcac ggataacaga aagctcgtct tgtgcagctt
    46741 ggagtgcaac atcaaggcga gcttcttctg catttgtatc tgcgactgta acagtctcaa
    46801 atgacaaatc cggctgaact agtagatatg ctttagcaac agcaacgccg tctgaggctg
    46861 caattccttt aagcatttct gtcatagtct tatgccaatc cctctttagt cattgtttct
    46921 tcaattgctg caatggcatc ttcagcatct gcaccttcag ctgagatagt aacatctgca
    46981 ccttgaccaa caccaagact cataacaccc atgattgatt ttagatttac tgctttacct
    47041 ttgtagtcaa gagtgatgtc tgaagcaaat ttgctagctg tttgaacaag caaagtcgct
    47101 ggacgcgcat gaatacctgt ttctgcaaca atgtgaaagt cttttgaagc catagtatgg
    47161 ttctcctttt aagttgtgta tttttgagcc atcacatgat aacccttaca acaaccgatt
    47221 atagcacaat gcttttttat tttcaagatt aaatatttaa acgacaaaaa atgtgaaatt
    47281 attttctttt attttcacgt ttttcacaat ttatttttca aactttaatg ctttattaaa
    47341 actgcttagc ttctatcacc aaaacgctag agctctaacc ataagaatcc agattgacac
    47401 aatatttagg tttctgtttt ttatttcaac acaatatgtt gtgttttaga taagtttata
    47461 gcttgctttt tagctttatt ttttatatgc tattatagta attccattta agatggaacc
    47521 attactaatt ttagaaggac aagacatgat tacagtatat tccaaaaata attgcatgca
    47581 gtgcaaaatg actaagaaat ttttagaaca acacggagcc aacttccagg aaattaatat
    47641 cgatgaacat cctgaaaaag tggattatgt gaaaagtctt ggcttcacat ctgctcctgt
    47701 tatcgaagca gataacctcg tattttctgg cttccaacct gcaaagttaa aagaattgat
    47761 ttaataagac aaggaaaaat aatatgagtc tcaaagatct tggcgatatt tcatattttc
    47821 gcctaaataa tgaaattaac cgtcctgtca atggtaaaat tccacttcat aaagacaaag
    47881 aagctttaaa agcttttttc gctgaaaatg tgctgccaaa caccatgtct tttacttcca
    47941 ttacggaaaa aattgagtat ttaatctcaa atgattacat tgaatcagct tttattcaga
    48001 aataccaccc tgaatttatt actgaattag ctggcataat caaatcagaa aattttcgct
    48061 ttaaatcatt tatggcagcc tacaagttct accagcaata cgccttaaaa acaaatgatg
    48121 gagagcatta tttagaaaac cttgaagacc gtgtcttgtt taatgctttg tattttgcag
    48181 atggtcaaga agacttagca aaagatttag ccgttgaaat gattaaccaa cgttaccaac
    48241 cggctactcc ttccttttta aatgctggtc gaagccgtcg tggtgaattg gtctcttgtt
    48301 tcttgattca agtaactgat gacatgaatt ctatcggacg ttctatcaac tctgctttgc
    48361 aattatcccg tattggtgga ggtgttggga ttaccttgtc taacctccgt gaagctggcg
    48421 caccaatcaa aggctatgct ggtgcagcct caggagttgt tcctgttatg aaattatttg
    48481 aagatagttt ttcttattca aatcaacttg ggcaacgtca aggagctggt gttgtttacc
    48541 taaatgtttt tcatcctgat atcattgctt tcttatctac taaaaaagaa aatgccgatg
    48601 aaaaggtgcg tgttaaaacc ttgtcactag ggattaccgt tcctgataaa ttctacgaat
    48661 tagctcgtaa aaacgaggac atgtatctct ttagtcctta caatgttgaa aaagaatatg
    48721 gcattccctt taactatctc gacattacca atatgtacga tgagttagtg gcgaacccta
    48781 aaattactaa gactaaaatt aaagctcgtg atcttgaaac agagatttca aaattacaac
    48841 aagaatctgg ttacccttat atcatcaata ttgatacagc taataaagct aatcctatcg
    48901 atggaaaaat catcatgagc aacttgtgtt ctgaaatttt acaagttcaa acacctagcc
    48961 ttatcaatga tgcgcaagag tttgtagaaa tgggaactga tatttcatgt aacttaggtt
    49021 ccactaatat cctgaacatg atgacctcac cagactttgg ccgttctatt aagaccatga
    49081 cacgtgccct aacttttgtt actgattcat caagcattga agctgttcca accattaaac
    49141 atggcaatag ccaagctcat acttttggcc ttggagctat gggactacat tcttaccttg
    49201 ctcaacatca tattgaatat ggcagtccag aatccatcga gtttactgat atttacttta
    49261 tgctcctgaa ttattggacc ttggtcgaat ccaataacat cgctcgtgag cgccaaacta
    49321 cctttgttgg ctttgagaac tctaagtacg ctaatggtag ttactttgat aaatacgtta
    49381 caggacactt tgttccaaaa tctgatttgg tcaaaagtct ctttaaagat cactttattc
    49441 ctcaagcaga ggattggaaa gctcttcgcg acgccgttca aaaagatggt ctttatcatc
    49501 aaaaccgcct agcagttgct ccaaatggct ctatttctta tatcaatgac tgctctgctt
    49561 ctattcaccc aatcacacaa cgcatcgaag agcgtcaaga aaagaaaatt ggtaaaatct
    49621 actatcctgc aaatggtttg tctacggata ccattcctta ctatacatct gcttacgata
    49681 tggacatgcg caaagttatt gatgtctatg ccgctgcgac cgaacatgtg gaccaaggct
    49741 tgtcattaac tctattcctt cgtagtgagt tgcctatgga gctttatgag tggaaaacac
    49801 aaagcaaaca aaccactcgt gatttatcca tcttacgaaa ctacgctttc aataaaggca
    49861 ttaaatctat ctactatatc cgtaccttta cggatgatgg ggaagaagtg ggcgcaaacc
    49921 aatgtgaatc ttgtgtcatt taattggtta agaagtaatg atgctaaagc atctattact
    49981 tctacggcag tcgctttagg cgatctgcct aaaccactca ctaactacgt aaggaaagta
    50041 ttatcgactt tccttactcc gtgtcgtaat tcctcgatat gctctaatga tgctaaagca
    50101 tctattactt cttgggcaat cgctttaggc gatctgccta aaccacttac taactcattc
    50161 gttacccttt tgaatctatt taaacttatt attaccggta aaactttggt cggttctact
    50221 ggtttatctc gatatcctta acgcacttta ctactcttta ggagatcatt tttctatgac
    50281 tacatattat gaagcaatta actggaatga aatcgaagac gtcattgaca agtcaacttg
    50341 ggaaaagttg accgaacaat tttggcttga tacccgtatc cctttatcaa atgacttaga
    50401 cgattggcgc aaactttctc ttcaagaaaa agatcttgtt ggcaaggttt ttggaggatt
    50461 aaccctactt gataccatgc aatcagaaac tggtgtcgaa gctattcgtg ctgatgttcg
    50521 cactcctcac gaagaagctg tcttaaacaa tattcaattt atggaatcag ttcacgctaa
    50581 atcttattcg tctatctttt caaccttaaa cacaaaaaaa gaaattgaag agatctttga
    50641 gtggactaat aataatgagt ttcttcaaga aaaagcacgt attatcaatg acatttacgc
    50701 taatggagat gccttacaaa agaaagttgc ctcaacatat ctcgaaactt tcctttttta
    50761 ttctggcttt ttcacccctc tttactattt gggaaataat aagctagcaa atgttgctga
    50821 aatcattaaa ctaattattc gtgatgaatc tgtacatggt acttatatcg gttacaaatt
    50881 ccagcttggt tttaacgaac taccagaaga tgagcaagag aattttcgtg attggatgta
    50941 tgacctcctt tatcagctgt atgaaaatga agaaaaatac actaaaacgc tttatgatgg
    51001 cgtagggtgg actgaggaag ttatgacctt tttacgctac aatgctaaca aagctcttat
    51061 gaatttagga caagatcctt tattcccaga tactgcaaac gatgttaacc caattgttat
    51121 gaatggtatt tcaacaggaa catcaaacca tgactttttc tcacaggtag ggaatggcta
    51181 tcttcttggt tctgtagaag ctatgtctga tgacgattat aattatggac tctaatagtg
    51241 ctcacgagac tgataatcta tcagtctctt ttcttaactt ttgttataat agccttatga
    51301 aacgacactt tttactcttg acattttacc tctttttaac aggtttaaca gctggccttg
    51361 ttgcttttat cttaacaaaa gccattcacc tgattcagtc cctcagtttt ggattcagtc
    51421 aaggttcttt tagcactatg attgctagtg ttccaccaca aagacgagct ctttcactcc
    51481 tctttgctgg actccttgca ggtcttgggt ggcacctatt ggctaaaaaa ggaaaggaca
    51541 ttcaatctat tcagcaaatc attcaagatg acatctcatt tagtccctgg acacagtttt
    51601 ggcatggttg gctccaatta acgaccgtat ctatgggagc tcctgtcggc cgagaaggag
    51661 cttcacggga agtcgctgtt accttgacgt ctctttggag ccaaagatgc aacttgtcaa
    51721 aagccgatca aaaactttta ttagcctgcg cttctggcgc tgcccttggt gctgtctaca
    51781 atgctccctt agccactatt ttatttatct tagaagctat tcttaaccgt tggtccctta
    51841 aaaatatata cgctgcctgc ctaacgagct atgtggctgt ggaaacagtt gctttattac
    51901 aaggccgaca tgagattcaa tacctaatgc ctcagcaaca ttggacgcta ggaaccctta
    51961 ttgggtccgt cctggctggt cttatccttt ccctctttgc tcacgcttac aaacatcttt
    52021 tggaacacct tcctaaggct gatgccaaaa gtcagtggtt tattccgaaa gttctcatcg
    52081 cttttagcct tatcgcagga ctcagcattt tcttcccaga gattttagga aatggcaaag
    52141 ctggattact cttttttctc catgaagaac cacatctgag ctatattagc tggctacttg
    52201 ttgccaaagc tgtcgctatc tctttagttt ttgcttctgg agcaaaaggg ggtaaaattg
    52261 ctccttctat gatgcttgga ggtgctagtg gcttactact agctatcctt agtcagtacc
    52321 ttattccctt gtctctatca aatacgttag ccattatggt tggtgcaaca atctttttag
    52381 gtgtgatcaa taagataccc ttggcggcac cagtttttct ggttgaaatt acaggccaat
    52441 cgttactaat gattatccct ttagcattag ctaacctcat tttttatttt agctatcagt
    52501 tttatcgttt catccttaaa tgattagtta attacttttt taataaaaag cttcggatga
    52561 atgaactgca ccccaaaagt tggacattat attttaagca aagttggact tggtataata
    52621 aagtagacac aaaattaagt ggaaacgagg aaaagtcatt atgccaagaa aaacctttga
    52681 taaagccttc aaactctctg ctgtaaaact catccttgag gaagagcagc ctgtaaaaat
    52741 ggttagttca actttaaaaa ttcatcccaa tagtctttat cgatggattc aagaatatga
    52801 aaaatatgga gaaagtgcgt tcccaggaca tgggagcgca cttcgtcatg ctcaatttga
    52861 gataaaaaaa cttgaaaaag agaacaaact gctacaggag gaattagctc ctctaaaaaa
    52921 gttccaggtc ttcttgaagc caaaccggaa ataaaatttc agtttctgaa ggaaaatagt
    52981 gttagcttga atagtcatca cgcctgtcaa actcttcagt ttctatgctt atttaaaacg
    53041 tcgtccctct tcaaggcatg ttgagaatga agctttgaag gaaatgatta aagccatttt
    53101 ctatgaacat aaagagcatt acggaagtgt acgaattacc caagaacttt gtagacgtgg
    53161 catccatgtc aattataaac gtgttggtag actccttcat cagctaggtc tctatgctaa
    53221 aggaagtcga tatcaatata aatactataa ccgtcgacgt tcttcatgaa ctcgtcccaa
    53281 tcttgttaat caatgtttcc aagcgactgg taagaataaa ttatggctag aagacttaac
    53341 ctacattcct acacaagaag gaatacttta tgtgtctgtc tttatagacg tttatagtag
    53401 aaagattgtt ggttgggcaa tgggccgacg tatgcaagac aagttggtaa cagaagcttt
    53461 caatcaagct tataatagag aaaagcctaa agaaggggta atcgtccata cagatcaggg
    53521 ttctcaatat accggagcat gatttcagga cctacttaga cagaaaaaat gtaagtccag
    53581 gatgaatcga aaaggtaatc catacgataa tgcactcatg gaatcctttt ataaaacatt
    53641 aaaaagagag cttgtcaatg atgctcattt cgcaactatt aagcaagctc agcttgagat
    53701 ttttaaatat agtgagactt actataaccc caaacgtctg cattcagctt tagggtatct
    53761 ctcacctgtt gaatttgaaa aaaatagtta ctcattagct taactttatg tctatttttt
    53821 cttgacaagt ccaaccaaat gttagttttt ttgtccaact tttggggtgc agttcatcca
    53881 tccgaagctt tttattatat gactcctaag cctattgaca ttaacaaaat gacttcaatc
    53941 aagttattaa aaatatgtaa caagatagca tcttttaagt ttcctcgtct ttgataggca
    54001 acaaagagaa aaatgcccat acagctgtac atgataaatt caacactatt ggtggcatgt
    54061 ggtaaagcaa aaacaagaga ggtcactaaa cctgccacct taagtgattt tcctttgaag
    54121 agatcaatca taggaaatcc tctaaagact agttcttcca taataggagc gataaaagct
    54181 atcacaagta caaatagggc agtataaagc gggaaaacac ctttgataag tctagctaag
    54241 gtatgtattg cagcatcatt agcactcact tgttgaccag accatagctg gttaacaagg
    54301 gtacctacaa tagctatcac acggatgatt aaccaaaata atgctaaata accccagtca
    54361 accaatctca ttttttgctg tttaataggg gtgtcttgct tagcttgata aagacgccat
    54421 aatacaataa ggacacttcc aacaataacc aagtagaaaa taccaattcc ccaattaagt
    54481 accataggaa tatcgtgttg cttttgcaat aaaatcatcg gaaggacatt gaaaaccata
    54541 gccagaataa tgagcactgc tatttttaaa taattaatga atcctttcat aaacagtctc
    54601 cttttaggct aacggtaaaa ttgtctggtc attgttgcac tcttaacgag taaatagagc
    54661 tgaattaaca ccaaaactaa gatggctgtt aactccactt gaccagtgaa tagatagaca
    54721 aaaaataaaa tcacatacaa ggaagggatg atgactccat ttaatgacaa cacactttca
    54781 aacgatgtct tatgataggc ttgtaactct gcctcatcta gagccatgat attatgtttt
    54841 aattctttca aatttggaaa ataaggaaca tcggttcccc gaatggcatt gtaacgtttc
    54901 atggctaaag cttgaaaagg aatgaccatt aataataaaa ggatatccag aagcggaatg
    54961 gccagcatgg catgctgtga atcattagtt aaggtcagac caagtagcac attgcacatg
    55021 gataaaatag aagctacggc aatcaataac atggtataag catgcttttt attcagctga
    55081 cggtaaccat tttcagaaat atcatcctct tcaattgtgt tataaacagc cgtctctttt
    55141 ttcagttgcg ttaaaaaaac aaaagaaagt gtgaggcctg tgacaactac tagacgattt
    55201 aataagataa tcaggttaat cacatcatct tttaggaacg tgagctgatc taatctctct
    55261 ccatggtaac ctaaaaaggc tccaaccatg ccacctataa tccctcccgc caaacttgat
    55321 agcaataaca tttttaacaa gcgtaaaaaa ctattcttct tctttttcat tcctcgacct
    55381 ccactagacg aaacacctct tcaactggtt cctgaaatac ctttgcaatt ttcatggcaa
    55441 ttataactga tggggtgtac tcgttacgct caatgagact gatggtctgc ctcgatactc
    55501 ctgccagttt agccatttcc gtttgattaa ttccatctct ggctcgtaat tctttgagcc
    55561 gatttttaag aataacctcc attgccatct ccttcattct tctttaactt ataacttact
    55621 ttctaaaata agaaaaagta ttcaacagca aggctagtcc tgtaaagccc aaaaccagat
    55681 aactcaaggg tactccaaac cagattaccc tgataagatg ataacttaaa atgaaaagag
    55741 tcaggatact tgcccataag caaatctgcc tcttaagttt gataccatgt gtcattttct
    55801 ctaacacctc ctcatgtcta tttgttacta taattgtaac atatcttttt ctttttgaca
    55861 acgataatag tcaaaaaggt tatgatggta gtcatttcaa atataaaaaa ccaagttcta
    55921 aataacttgg ttttttatgg gtttacactg tttcagcaac tgctgctagc agctctgcaa
    55981 ttttacttgc atcgctacca cctgccatag ccatgtctgg tttacctcca ccacgacctg
    56041 ctacaattgg tgccaattct ttgatcatgt taccagcatg gacatctttg gttttgcttg
    56101 caacaaggac attaaccttc tcaccaatag ctgctacgag aacaagcaca tcagagtagt
    56161 ctttttgttt ccagttatca gcaaatgtac gaagtgcccc tgcatctgca acatcaactt
    56221 gactagcaat gaagcgcacg cccttagctt cttgaatatc tttaaagaca tcaccagctg
    56281 ctgcagctgc tgctttttct ttaagctctg cattttcttt ttgaagatca cgaagtgagt
    56341 cgctaagagc ttgtacttta gctgctgcat ctttcaattg cggagctttt acagtagcag
    56401 cgatctcttt tagggcatcc tcttggttac gataagcttc aaaagcttgt ctaccagtaa
    56461 ctgcaataat acgacgagtg cctgaaccaa taccttcttc tttgacaatc ttgaagagac
    56521 cgatttctga agaattattt aagtgagttc caccacaaag ttcaacagaa taattaccaa
    56581 tttgaaccac acgaaccact ttaccatatt tctcaccaaa aagcgccatt gctcccatct
    56641 cttttgcggt ttcaacgtca gtttcagtcg ttgtgattgt aagagcgttc caaatttgct
    56701 cattaacttc ttgttcaatg tgacgaagtt cctcattgct tactgcttca aagtgagtaa
    56761 aatcaaagcg caagaattct tcttcgttca atgaaccagc ctgagttgcg tgttcaccga
    56821 taacattgtg aagagctgca tggagcaagt gagtagctgt gtggtttttc tcaacagcca
    56881 aacgacgctc tttgttgatt tcaagtgtgt agtttgttcc aactgaaagt gatgccaaaa
    56941 cgtttacagt gtgtagaggt tgaccattag gtgctttttg aacatcaaca acctcagcaa
    57001 ctgtgtcacc cttatcattt ttgattctac ctgtgtcagc aacctgtcca cccatttcag
    57061 catagaatgg tgtttgagca aagacaagaa gagcttgacc ttctgaaaca gcttcggtac
    57121 gttcattatc agcgatgatg actgaaagac ttgattcaag actatatgtg tcgtattcga
    57181 atcgtgattc ttcaacaata ccagctaggg tttcattttg catccccatc gaaccaccct
    57241 taacaacagc tgcacgcgca cggtcttgtt gttctttcat ggctgactta aagccttcgt
    57301 ggtcaatatt gtagcctgca tcttctgcca attcctctgt caattcaacc gggaatccat
    57361 aagtatcata aagtttgaag atatctttac cttcaagagt atccttacct tcagccttaa
    57421 gctgcgcaag caatgaatcc aaatgaccgc tacctgcatc gatagtacga gcaaatgttt
    57481 cttcctcacg tttaacgatt ttctcgataa aatcacgttt ttcaagcact tctgggtagt
    57541 agctttccat gatttgtcca acagtcggaa ccaatttgta aaggaaagtt tcgttgatgc
    57601 caagacggcg gccatgcata accgcacgac ggagaagacg acgaagaacg taaccacgac
    57661 cttcatttcc aggaagcgca ccatcaccga tagcaaatga aagcgcacgg atgtggtcag
    57721 cgataacctt gaaactcatg ttgtcgccat ctggatcgta agttttacct gacaattttt
    57781 ctacttcacg gatgataggc atgaaaaggt cagtttcaaa gtttgttttt gccccttgca
    57841 taacagctgc aagacgttca agaccagcac ccgtatcaat gtttttgttt ggtaattctt
    57901 tgtattctga acgtggcaca gcaggatcag cattgaattg tgagagaacg atgttccaga
    57961 tttcgatgta acgatcgttt tcgatatctt cagccaagag gcgaagtccg atattttctg
    58021 gatcgaaata ttcaccacgg tcgaagaaaa tctccgtatc tggacctgaa ggaccagcac
    58081 cgatttccca gaagttatcc tcgattggca ccaagtgact tggttcaacg ccacaagcaa
    58141 tccaacggtt atacgaatcc ttgtcatctg ggtaataagt catgtagagc ttgtctttag
    58201 ggaaatcaaa ccagtctgga cttgtcaaga gttcaaatcc ccactcaata gcttcatcac
    58261 ggaaatagtc tccaattgag aaattaccaa gcatttcaaa catagtatgg tgacgtgctg
    58321 ttttaccaac attttcaata tcattagtac gaattgattt ttgtgcattg gtaatacgtg
    58381 gattttctgg aatcactgaa ccatcaaagt attttttcaa ggttgcaaca cctgagttga
    58441 tccaaagaag cgttgggtcg ttcacaggaa ccaagttagc tgaaggctca acgcaatgtc
    58501 ctttagattt ccagaaatcc aaccacattt ggcggatttg tgcagacgat aattctttca
    58561 taaaaattta gatacaaaga gtaagaaaaa cagtgttatg ctgaagctag taatgtaatc
    58621 acaccagttg acacagctcg tctttcttgc taggagatca gctataagcc tggcagccta
    58681 gtctactcta ttcctttcgt tgatttcaaa tagtcctcaa tacaaaacaa gtccatctca
    58741 cagagggcga aaaccgcggt accacctcta ttcaatgaac ttgtcattct taatttacga
    58801 tatcaattgt tgtaaagtta agtagcatgt ttatctaatt atcaatgact cgcagcaaac
    58861 gtcacttttc tgtatctaat ccttgataaa caattcttaa ctaaattatt ataagttttt
    58921 ttaactgatt agtcaataaa atcctactta ttgtgcagct ggctcttgcg tctgagcctc
    58981 agtctcagtt ggttcttcag ctgatgatgt ctgtgtttgc tctgattctg atgggttctc
    59041 ttctgcagct tttgatgatt cgctggttgt tgaactttca cttgcagctt tagttttttg
    59101 accaagattt gcatattgcg ccaaaatatt agcaaaagct ttgtctttaa tttttacatt
    59161 agctttatcc aatgcatttg caataacctt gttttggaaa ttcatatctt ttgatttttc
    59221 agctataatg atagctttca aacgtttctt atattcttgc caatctgatt ttttttctgc
    59281 ttttttagtc accttaacaa tgtaaaactt cttttgataa gaagttggat ctaaaaccga
    59341 gataacgtct gatatgccac cctcattcaa acttgaagcc gcttttacga catcagtcgg
    59401 tacatttgtc gcgcctgaat caaatttata ggtcactttt ttctcaggtg ttgttgtttt
    59461 ttctttagca atagctgtaa agtctgcgcc ttcggctttt agttcctcta agactgattt
    59521 agctgtctct tcattatcta aagtaatcat ttcgactgcc attgttggag tataagattc
    59581 atatgctttc ttatattctt gtgttgtcaa ttctttttta gctgcttctt taaccgcata
    59641 ttctactaat tttgaagagc ggatctgacg cttaaaagtc tcaggtgtca agcttgattg
    59701 tgccaaagca gcagagaatg aagcgccata ctgttcagct gttttatgat acgccttttc
    59761 aacttctttt tttgaaacct tatcaccata ttgagcttca aaaacacgac taattaccag
    59821 atttagcatc gctttttgcg atacttctgt gttttttgtt tcattgtaaa aatcactaac
    59881 gctaattgta tcacctttca tcgaaataac cttagtattg tcattagttg attgacaagc
    59941 tgctaaagcc atcactgagg ccaatgtcac aacactagca atgagtttat ttgagttttt
    60001 catttacttc tgagctcctt tttatcttta actaatttat tataacataa atttatcaat
    60061 gttacttaat ctggtaatag aatatctgct tgatttttac gaatcattaa taatccatca
    60121 ctaagaggga ccaggctagt tgttaggttt ggatgagtta aggtagcatc aaacaaagac
    60181 tgtaagccac gataaatagt acgctgacct cgtcgaatgt cttcgatcgg ttttgtaatg
    60241 tcacctcctt gaaagacatc atccaaaatg actacaccac cgacttttag cagtcttaaa
    60301 atctctggta gaaagacaat atatttggat ttggcggaat ccataaacac aaagtcaaaa
    60361 tttccttcaa gtgtagataa tatatctgct gcatctcctt ctaacaggcg gatctgttgg
    60421 cgactgtcgt acttagcaaa atttgcttta gcaaaatcga tcatctctcg attacgatca
    60481 atagtcacaa tcgtcgcatc tggtgcattt tcagccatta aaagcgcaga aaaaccaatg
    60541 gctgtgccaa tctccaaaat gtgttttggc tgtaagcttt gcaataaaaa cctgaaataa
    60601 gccacgacct caggctgaat aataggaatg ttttcttgtc ttgcgaattg ctctaactct
    60661 gctaaaaaac ctgtggtttg cttctgccgt gttcgcatat aatgaacaag ctcttctttg
    60721 acaacaggac gacgcatatt atgatttgct gttttactgt atgatttaac cataaaccta
    60781 attatataaa aaaaccctag gctttgctag ggtttacttt taaatttttt ataggacatc
    60841 atttcttcaa ccttaatgct accattaatc ctaaaatgta taagacaata aaaacacata
    60901 aggtaagaag ataattatga gtccattcaa cagtgataga taataacata ggtccagtta
    60961 atgcagctat tgcccaagct gtcaatatat acccatgtaa tgtagccagt tcctttgccc
    61021 caaaaagatc acttaaataa ggcggaatga gagaaaaacc cgcaccataa caagtcataa
    61081 gggtggcaat gcttatcatg aaaattaggg aactatgtgc aaatattaaa ctaatagtca
    61141 taattatgct taccaaaaat aaaagtatta ctgtcacacg gcgtccaata tagtctgata
    61201 aactagccca tactaaacga ccgaaaccgt taaaaatccc catagcacca accacaattg
    61261 ctgacatttc tggactcata ccagttagat cttgtgccat tggcgcaaca actgagataa
    61321 gtcctaagcc acatgtgata ttgataaata aaattaccca aagacaataa aatgattttg
    61381 ttttaagtgc ttctttagcg gtcattcctt cgattaaata actgttattt tgtaatcttt
    61441 ttttatctag tatagctatc tcagcagcag ttggttttat tatcaattga gaagcaaaaa
    61501 gcataactat tagataaatc agccctaaaa ggtaaaatgt tgctaccaaa ccttctgttt
    61561 caattagcca ctgggcaatc ggacttgtta ataaagacgc aaaaccaaac cccataatag
    61621 caaaccctgt tgccatgcct cttttatctg gaaaccattt tataatagtt gatatcggtg
    61681 tgatatatcc cgctccaagt cctaagccac caataacacc ataaccaata tataaaagcc
    61741 aaatttcttt acgatcaatc gctaaaccag tcagcatatt tccagaagca taaagaatag
    61801 ctgacaccgt tccggttaga cgaggaccat attgttcaac taaatttccc ataaaagcag
    61861 cagataaacc taaacaaaaa atagctaaag aaaaggcaaa agcgacagga gcttggtccc
    61921 aaccggtctc ttgtaaaatt ggattacgat aaacactcca agcataggtc gatcccaaca
    61981 ttaagtggag aagtatccct gctgttgcaa tgatataacg ttttgttttt tccatgaaaa
    62041 actccctttt tattatacga acgtttattt tttaaaaaac ataaatgtta gtattttaat
    62101 tctattatct cttttataaa atgtcaaata taataaaaat atgttttatg cgaacgttac
    62161 ctctaaaaca atagaatagc gttaatctga agcgccttac tcaaccattg gttttattta
    62221 agtgagtgac cacacaataa aaaagacaaa aaagaaaccg tcaaactaag gtcaatgaag
    62281 cctgcttttc aggactgata atccactaaa atataaaaag aaaatgaccg atagaaatgg
    62341 agattcacac caactgtgaa tctccatttc tatcaatcct aaactctttt tgtccttgac
    62401 ttttgtgatt ttagcttttg tgtatgcctt tggacacaag tacttcaagt tctgttagac
    62461 gttcgtcaaa gactttaaag gcggcttcca aataatcacc ttttgccata tcaacgcctg
    62521 ctttagcaat cacttcaagt gggtaatcag aatttcctga cttgaggtag gccaagtaat
    62581 gatcgatatc atcttgtgtg ccatgcacaa tctcatccgc taaatagctt gcagctgcaa
    62641 aacctgttgc atattggtaa acataataat tgtaatagaa atgaggaata cgtgcccatt
    62701 catactgaat aaaatgatta tcttttttac ttaaaccata atatttttca tttaaatcag
    62761 cgtatagctg gttaaggtat tcacttgtta acacttctcc tttttgatca gcttgatgaa
    62821 tggcatgttc aaactcagca aattgggttt gacggaaaac tgttccacgg aaaccatcga
    62881 ggtaatggtt taaaatggca aagcgttctt tctcatcttg cacttcattt aagagagctt
    62941 ctgtcatgat gttttcattc gttgtggatg caatttctgc caagaagata ctataatccc
    63001 catacacata aggctgtgtt tcacgagtga aagtagaatg caaactgtgg cctgtttcgt
    63061 ggacaagtgt gtaaagatta tcaagtgtat cttgccagtt taatagcatg aaggcattgg
    63121 tatcatagga accacctgaa taagccccag agcgcttccc tttattgacg tgaacatcaa
    63181 tccaacgttc ggtaaaagca cgatgtacac gatctgcgta atccttacca aaaacagcca
    63241 aaaccttctc agccttttcc aaagcctcat cataaccaat ggctaaatct gtttcagata
    63301 atggtgtgta aacatcatac atcttcaaat cgtctaaacc aagaacctct tgacgcaatt
    63361 tcaaataacg gtgtaagagt ggtaaatgtt tgttaaccgt ttctaataaa gtgtcgtaaa
    63421 cagcttctgg aataaagtca gcagccatgg cagcttgacg tgctgaatcg tatttatgaa
    63481 cacgcgcctt atagttttgc actttcacat tggtttgcaa ggttttagcg taagtatgtt
    63541 ggaactgttc ataagtacta tacatggctt cataagcagc ttggcgaacg ctacggtcct
    63601 tagattccat taggctaatg aagttaccat gggttaattc aacgttttca cctttatcat
    63661 ttctgactat cgggaaaaca atgtcagcgt tatcaagaat actaaaggtt tcttccgcac
    63721 cattgaaaat ttcttgagct cctgctaata attcctcttc tgcttgacta agaacatgtt
    63781 cgcgggcttg gaataatttg tcaaagaaat ggttgtacac tttcaactca ggggtttcag
    63841 taaggaaagc ctgatagtct tcttgatgaa gcatcatcac ttctggatca tagaatgaaa
    63901 agacttcgct aaactttgca tacaagcctg aagccttagc ttggtattct tgatacttgg
    63961 caacagtagt gtcttggtca tttttcatgt gagcataaac atagattttc tccacacgac
    64021 gagccaattc taaatatgtt tttgtaacct ttaacaaatt agcactagaa tccagcaaat
    64081 gaccagcaaa acctttagat gcctcaactt cagtagctaa gtcactgact tcagcttccc
    64141 aatccttatc tgttgcaaaa atagtgctca aatcccaagt gtatttttct tctaaatggc
    64201 tgcgattatc agtcataaca tctccttctc attttctatt actatccatt ttaacataat
    64261 attttggtga aaaaagcgtt tgcaccttct tatccttttc ttttttataa tagactttaa
    64321 aactttcata ataagggcga agatttcctt taatttgaca aaaaccgctg gaagattgaa
    64381 ctggtctcca ttgaggataa aaagcatcag ttgttaacat aagtaaatta tagcctgata
    64441 agtaagcctt ttcttgtcgt cgtagccatt tcgggtgtct agctaaaaga gctctttgta
    64501 ttcttttaga taggttcaca gtcatttttt tctgataaga ataaaggatt tcttgctgat
    64561 agggtaatcg aaacatttcc ataatattgt ggtctaaaga aatggttttg gttaggtaac
    64621 ttaccttacc aaataagtct tcatggatta aatatttgag acgtagcaga tttgcagctg
    64681 catccagctc ccacaaatga aagcccaaac tagatgaaaa gtaaagaaac tgtttttgca
    64741 aagcagttaa gtgagtgtta agccacaatt ttcttcccag taaccatcgt accggatacc
    64801 ccttttcttg ataggctttg gtgcgtttct ttagacgctc aactggcaag ggactgcact
    64861 gaatttctaa ggctaactta tcattcaccc aaaggtctgc tatctgttgc agctcaggaa
    64921 gatatttttc aatacagaca gcttctgttc ggactaaact ggtgtaaagt tttgccttca
    64981 acgtcaaatg ttcctcagat tcattttctg cttggaattg acaatgagct agttgtacat
    65041 gggcaaaatg aggtcgtcta attgtcccct gacgcaagcg aacaggagat ttgcaagctg
    65101 ggcaacaaaa aggcggtttc gttgaaatag gctgagttac tagcgaaatg agctgattct
    65161 taccatctaa agcggttaat atttttgtca cctcctatta gatcttccac cttattattc
    65221 gaaaactaag taccaaactt taagtagctt tagttttttt agccatcaaa aaacactccc
    65281 atttccaatt tatgagagtt taacacaagg gtttttataa cgcttcaggt taaggagaca
    65341 gtgagaattg aatctttttg cttacctgat tttgtaacaa caagatgact aaacatagca
    65401 aaagtcggac tcatcatgac tataatagtc aatggacact ttattgatta agcaagaata
    65461 gcttcttttt gaaagcatgt tttgctcagt ctagatacgt tttaatgagt tgcctttctg
    65521 actctgttag ataacgatat tctccgctgg ctaaatgacc gagttccagt cctgcaaagt
    65581 gcgtccgttt cagagaggtc actttcaaac cataggtcaa aaacattttt ttcacttggt
    65641 gaaattttcc ttctgaaatg gtcaaactag cctgtgactg gtctgtatcg gctttaagaa
    65701 tagtcaattg agctggttgg cattgttcac ctgttgggaa acaaatacca gctgcaaaaa
    65761 aatctgaggc atcttctgct aacaagccat taacggttac aagatacgtt ttagaaacat
    65821 gatgactagg gtgcaacatc cgaaacccta ggggaccatt atcagtgagt aaaaccaacc
    65881 cttcggtatc tctatccaat ctgccaacag gatacaagtc tggactttta tcttcttcag
    65941 caagctgatc aataacggtt aaatagttag tatctttctt agctgagacc acccctgatg
    66001 gcttgttgag gataatgtag gaatgtttag gatgcgtcac tcgctgtcca gtcacctcaa
    66061 tcagttgcaa gccaggatca acattttgtc gaccatttct ggcaggcatg tgatcaaccc
    66121 aaaccccttg agccttaatc agtttcttca cttgacttct agagccaact tttgtacctt
    66181 ctaataattt atctaaacgc atattagtag tgtaacataa atttaccctt gcaaaagaaa
    66241 tagaagttac aagacttctt cttaaatgag gttgactatc tcctcatttt tgttcttaca
    66301 aggtttaacg actggttagg tgaatctaat tgtgacgcag cagcttcatc cacaatgacg
    66361 ataacatgat catgtttttg gagaatactt gctgggaggt cttctgtgat tggtccaaaa
    66421 accattccct tgatcgcatc agctttttct tgtccaaagg caagaagaac aatcattttg
    66481 gacttcatga tggaggcaat tcccatagag atagcttgtt ttggcacatc ctcaatactt
    66541 gtaaagaaac gactattggc ttcaatggtt gattcttgaa gatccaccac atgcgtttct
    66601 tcttcaaaag aggtcccagg ttcgttaaaa ccaatgtgcc cattacgccc aatcccaagc
    66661 acttgaaaat caatcggatg ctctgcaatg atttggtcat atcgtttagc ttctgcttcg
    66721 acatcggttg ctaaaccatt gggcaagtaa ttctttttaa aaggcttcgc attaaaaagg
    66781 ttttgacgca taaaataatc ataactctga tcgctctcta ctgaaagacc gacatattca
    66841 tccaagttaa tacttgttaa gtccgaaaaa tccaaaggac ttttgaccat ttcttggtaa
    66901 aaactaattg gtgaacttcc tgttgctaat cctaacgtct tagctccctt agctaagcta
    66961 tctttcaata aggtaaaagc gattttccca ccttcaatct gatcttggac ccgaataatt
    67021 ttcatgtcat tctccttttc taattggtat agacctttcg tgtttttatt atatggtata
    67081 taccaatttt tgtcaagcct atcctttact ttctgatgaa agattaaaga tgacgggtta
    67141 gacgacaagt gatataatag aaaagattta tcttacatga aagagttact aggaagagat
    67201 ttactagtgg ctttaaagga gccccaatga atactaacga ttttgatttt gagttaccag
    67261 aagaattgat tgcccaaacc ccactcgaaa aaagagacag ttcaaaacta ttgattattg
    67321 atcaccgtca aaaaactatg gttgatagcc attttgacca tatcattgat caattaaatc
    67381 caggggatgc cctcgtcatg aataacaccc gtgtcttgcc tgccagactt tatggagaaa
    67441 aacccgatac tcatggtcat gtggaattgc ttttgcttaa aaatacacaa ggagatcaat
    67501 gggaagtttt agccaagcca gccaaacggc tcaaggttgg tagccaagtc aattttggag
    67561 atgggcatct caaagccacc attatcgacg aattagaaca tggtggacga attgttgaat
    67621 tcagctatga tgggattttc ttagaagttt tagagagcct cggcgaaatg ccattgcctc
    67681 cttatattca cgaaaaatta gaggatgctg agcgatacca aaccgtttat gctaaagaaa
    67741 atggctctgc ggccgcccca actgctggtc tccacttcac aacagacttg ctcaaaaaaa
    67801 tcgaagccaa aggggtacat ttggtttatt tgaccctaca tgtagggctt gggactttta
    67861 gacctgtttc cgtggataac ctcgatgagc atgatatgca ttcggaattt tattccctct
    67921 cagaagaagc agcgcaaacc ctaagagacg tcaaacaagc tggcggtcgt gttgtcgctg
    67981 taggaaccac ctctattcgt acgttggaaa ccatcggaag taagttccaa ggggacattc
    68041 aagctgattc aggttggacc aatattttta ttaaaccagg ctaccaattc aaggtagttg
    68101 atgctttttc aactaatttc catcttccaa aatcaaccct tgtgatgcta gtatcagcct
    68161 ttgcagggcg tgactttgtc cttgaagctt acagacacgc ggttgacgaa aaatatcgtt
    68221 tctttagctt tggcgatgcc atgtttgtca actaaaaacc tatgaaatta cttggaaaat
    68281 ggctattctt cttgatgttt ctgacttttt gcgtcagttt ttggcagaaa gactatcagc
    68341 ggattgcctt tgaaaaagaa cacaaacttt atcaagattt agtggcacct ttttaccaaa
    68401 actatcctaa attacgagaa ctccagcttt cagaagctat taaattacgc cacgacttgc
    68461 ttgattatgt tcgaaaactc gataaggacg gatggtccta taaagccatc caaaaaggat
    68521 accttgaaca actcgctgtt agaggaaact cttatcattt cgaacaactt tatagtcgca
    68581 ttcgcctgat aggatcacct gactttcaaa agctctggca acaagaagag atggcacaga
    68641 cgcctcaaga agctcaaaaa cggctacagc tgctcttgac gtatttaaag atgccagacg
    68701 agttgacagg acaatcaaaa caaacacagc aagtattggc acaattaagt ccaaagctat
    68761 cgccaacaga tcctttttgg gaccaattat ctaccctgat tcaggcttat tatgttaatc
    68821 tcgaacacat tccttatagc cgttttaatc ggaaaattca tcaactccgt tacctcatat
    68881 caacccagca aacggagtgg gttcgctcac attatgggaa taaagagaaa accgatgcgg
    68941 atgccttagc caaatatttg gctactctag aagatgacga ttatgctctt tatgaatctt
    69001 ctagatacca taataaggtt gctagtattt tagatgctaa tggcaatcat caggcactct
    69061 atacagacaa tattcctcaa accaactata agattttgat tcattttcac tcagagttta
    69121 ttttgtcaga atctggacaa tttttagtag cactagatcc tgataaccta acgcgaaata
    69181 gtattgtcaa tggttcttct ttcaattatg gcaaccaaaa cgatgacttg caccgtctgc
    69241 ttgatattga ccctattctg ctttttgatc cggcttttat tgaaaaagca attaatagtc
    69301 ctgatgcaac ttttctagtt cccgatttag aacagcaaag ggataagcac aatcccattt
    69361 acagcagaaa tggcaaatca tctaagcagc taacacgcgc tgccgttaaa aaattcaaaa
    69421 aattgcttca ccattatcaa gaaacaagag gtgacaataa gacctcaaaa acacagcatt
    69481 aatctcaaaa agcttgacct gaagaaacag gccaagcttt tttaatgagc aaaaacttat
    69541 tttagtgact ttcataagta agtatgtcta ctatcagact aatgtcaact gagtattaga
    69601 tcatgttgtg attgactcta tgccactcat taattacata tgttagctga acaagctgca
    69661 cataaccaag gccattgact tcctctgatg cttgtgttgc tccacccaaa ccagatgaat
    69721 aaagagcaat caaataagga gactcttcgc aaacaatggc acctacattt aaagcttctc
    69781 tgacataacc cggtttttga taaaccttta catgaggcaa ataagtcttg taatacaaat
    69841 cagggaaaga ttcaccaatg tagtacaaga tatccttata tttatcctga tgctgccaca
    69901 agtaatccaa aacttgcaaa tagtaagcgg tggtgatttt attgccatta cgatcagtgg
    69961 tcgtaatagc cccggatacc ttcccgtagc ggtcaaataa ttggtaagcc ttattcatgc
    70021 cacccaatcg ttctgctaga gcataagctg gcgtgatttc tgagtatctt gcatatccgg
    70081 aatagacatg gcaccattga actgagcaac ataggcatga tgttcctgat catattcata
    70141 atcagtttct gtaatgtcaa aacgctctgt catggataat ttgccttatc taccaccagc
    70201 atgtttaatg gcagcttata ggtgcttcct gcaatcattg gctgatggtc attcatggca
    70261 gcagtcctgc ctgaattgag gtctttgtag gaaaaggcaa tttgggattc accaatgcca
    70321 aattccttta aatacacctt gaccgtattg accaaactca aatggttgtc atcgtaatag
    70381 agccctaagg catccatttg cgctaaatct gcatccataa cagcttgctt agcctcttta
    70441 gatttttcag gtaacggttt ttgaacagtt tttctaatct ttttttcatt tttaagtcag
    70501 ccgtttgctg ccgctcacct gctttaggag gaaagccttt ctttttacca gtcaaacagc
    70561 cgacaagtaa ggtcactatc atcattccta aaataatccc tacaatggta gttttcttct
    70621 ctcttaacac ctaaaacctc ctatccattc tattctagct aaatttagct aaaaaccaag
    70681 gattttcatt aaaaagacag attattttta ttttttctaa aaaatgatgt ccccacactg
    70741 ttattcaaaa aagcacttaa aaaaccaatc tctttttgag attggaaacc cttttcttat
    70801 ttagcggctt ggtaaagttc tgatactttt ttccaattaa cgatttcaaa gaaagctttg
    70861 atataatttg gacgtacatt acgataattc aagtagtaag catgctccca cacatcaagc
    70921 gctagaattg gttttttgcc ttctgaaatt ggagtatctt ggttagcggt tgatgtgatt
    70981 tcgagttgtc cttctttatt aacaactaac catgcccaac ctgaaccaaa acgtccagta
    71041 gcagctgctg taaattgttc tttaaaggcg tcaaatgacc caaaagcatc atcaatggct
    71101 tgtgcaacat caggagtgac gtcttgtttt tcaggtgata atagttccca gaaaagcgca
    71161 tggtttaggt gtccgccacc attattaatt aaggcttgac gaatatcttc tggaatctta
    71221 gtgacatctg ccaatagttc ctccagattt tctccgatct ctgggtgttt ttctaaagcc
    71281 gcattggtat tagcgacata agtggcatgg tgtttatcat gatgaagagt cattgtctcc
    71341 gcatcaaact gtggttcaag agcatcatac gcgtatggaa gttctggtaa aataatagcc
    71401 attttcctgt cctcttttcc tttatgatac gtctatctta tcgcaaaaaa taagagcttt
    71461 caactaattt gattatctct tggaaagcgg tccaacgcct atttttgaga gtgagtcatg
    71521 atttttaaga gagcaatatc aactagataa ctcttctcat aaagtcctgt ttttatctgg
    71581 taatctgtct caatcaaggt tttcaccgct cctgttagaa aggcaagaga taaggtccta
    71641 gaatccttta acgcatactt gacctggtaa ggattaaccc gccgaccaag tatctctgac
    71701 aaactggtta caagctgctg ttctgatttt ccttctttag caagaatggc aagctgtaaa
    71761 tataagcgaa attgccccaa cataatagca attaatttaa tatcatcttc ccctgataag
    71821 cgtaaatcat gaatcaaatc tctagccaca tcaactttac ctcctaggac aagtctggtt
    71881 aagtcaaaaa tattatcttg taaactttta ggaatggctt gctcaatatc agttaggcta
    71941 atatttcccg tttttttata ggcttttaaa aaagccatgt ttttcatgat ttgactaaaa
    72001 tcatcgtttg attttaaaag cagttgttca aaagcgccac tctcaaatcc caaacccagt
    72061 tgatgactgt atttttgaaa ataagttctt agctctgctt ctttcagagg gttggcttct
    72121 aaaacaaggg catcacgttt caaaagctta acaagccgtc tcttactatc caatttacct
    72181 ggagcaaaga taattagtcg agtagtctct aagggatttt ctaaataggc ttcaaaggcc
    72241 tttaggtctt tttcttttaa gaaacttttt ttattggtcg tgatatctaa caaatggtca
    72301 aaaatgacca ccttctgctc agcaaagaag ggtaggctca ctagatccat ttctgcatcc
    72361 tgataagcgg cctcagacat atcaaagtaa gaataggcca aatcatcctt atcaaaagca
    72421 atctgctcca ttaagcggga tttcaactgg ctatactgac caatgtcatc tcctgtgaca
    72481 agggttataa gacccaaatt ttctttactc agtttttcaa tcttttctat cgcaatcatg
    72541 cttttattat atcatctttc tcctaaaagg aaagcgactg cttgtttctt cgtcaggctg
    72601 gaattttaac taacggaccg tttcaagatg ccagcttgtc caaccagtca aacgaatagc
    72661 tccttgcgta tccgttcggt aataagtaat ttgtctgtct tccaaacggg ctaaggtttc
    72721 tctgtgagga tgctgataac ggttattttt tccagcagaa ataaaggcca ctttaggttg
    72781 aatatggtct aaaaaagctg cactagaaga ggtatttgat ccatggtgac ctgcttttaa
    72841 ataatctact cttagttgag gataacgttt tatgatctcg ttttccccct ctttttccaa
    72901 gtcacctgtg aaaagaaaag ttcgatttaa gagcctgcca taaagtacca aagaatcgtt
    72961 atttttcccg tcccctaact gccaagggta gagtacctgt aagacacttc ccataatagg
    73021 caactggtct ccagctgcta aaaccctaac gtgacatttt aaacgcctta gccgcctaac
    73081 aaagcttgga tggcttaaac tgccttgact agtcaaaatc tcctttatcc gaatagcttt
    73141 ggcaaccact tcgatatccc ccatatgatc agtatctgcg tgagttacta atagttggtc
    73201 aattgtgtga atacctctac tttttaagta aggaattaag gttttctgag cattagctac
    73261 gtgatgtcct cgtcgccagt gctcttttga agaaaagaaa gggcgcccac ctacatctat
    73321 taagagattt ttccctgtcc actccctcac caaaatacta tctccctggc caatgtcgat
    73381 aaaggtcact tcattggtca aaggatattt gacagacaaa agcgtcaacg ctataaccaa
    73441 accgcaagtg ataactcgtt gtcgcacctg ccgataatca taaaaaatag cgaagctaat
    73501 caccaagata agcaagtgcc aactggtcgg gcttccaaaa acaagggaac tattgaaagt
    73561 atttccgaga aattgaatga ctttttctaa taaaataaaa agatggttac atattgagac
    73621 agtcaccaaa ggggatagac aaaaaaccag acaaagaagg ggcaaaataa aaaggtcaaa
    73681 gagataagac aagagccctg ttaagaccat tgacatgggg ttaaaactag aaaaataaaa
    73741 gagcaaaaat ggtaatattc ctagggaaat ggtcaagact tgtaccaact gtcttttagc
    73801 tcctgataat tcttcaacag taaccactgt taacaaaaaa gcatagctaa acgttaatac
    73861 gccaccaaca gtcattaaga aatgagcatc ccataaaaag acaagtaaaa aagtacaagc
    73921 cagattgtct aatcctttta ttcctaaatg acgcaactgc gactgcacga ggcttcgaat
    73981 aacagaaata ctataacctg tcaacgcggc ataaaagcaa gcaaaaggaa gctctatcca
    74041 ttttatccat tccaaaggaa ctgcgagtaa tagcaacacc cttctaaaac aagtaagaaa
    74101 gaagccaacc tgcatccctg ataaagcaaa gagatgaatg atacccaact gactataata
    74161 atctgtcatc tcaccaaacg acttatctaa ataaccaaaa aggaggcccg tcaggtagtg
    74221 agacataggt cttggaaaat gctgctggca atgaacaatg gctcgtcgtc ttaaagagga
    74281 caaatagtca catattgact cgggtgaaat cacttcaagc tgttctattt gctctacctt
    74341 ccctatcctg taaattcctt gataagccaa aaaagtctga taattaaagc ctttaaaatt
    74401 tcgaacttcc ttagcttttt ccaatgtcac ttttgcgtgc atcactaacc aacggtgctc
    74461 tttcttgaac aattgggctt ctgcttggct tttcaaacgg taaaataact gataagaatg
    74521 tttcccgtga cgtccaagaa cagctaattg atcaccatta atccgaatac tatcaggaac
    74581 taatgctaca gaggttattt gtactggctg aatttccagt ttttgaatca actgctgttt
    74641 ctgatacagc aaaaacaaag cacagaaact aaggatggca aagacaccga gaaattcttt
    74701 tttagacaaa cgcttgacaa gtaagcaaat caaactaagg ctaaggagaa acgttaacca
    74761 gctagggcta tggatttgat aaaagagaac caagattaaa aaagcaaatt gaatctttga
    74821 caggggcact agcttagtcc aagaaaatgt catcttttaa tttctcgagc gttttttcgc
    74881 caatccccga aacctgacgg agatcttcta acgctttaaa accacctaac ttatctctca
    74941 tatcaataat atcctgagct cttttagcac caatacctgg gatatgttgt agttcttcta
    75001 agctggcctt attaatatga acctttgact gatccttgct ggcagtttct tttttaccag
    75061 aaactaatga tcttggtagc acagaaatct cttctccttg tttaggtaca taaacaactt
    75121 gctcatcagt tagtttttct gcaaaattaa tagcatgttt atcagcttct gaagttaggc
    75181 ctccagctag ttcaatgaca tctcgcacac gactgctagc agttagctta taaactccct
    75241 ctttttgtac ggcgcctttt aaatccacta aaatactgct atcttcttga atttcctttt
    75301 tttcttcact aacctgctgt ttcacaggcg atatttctct caaagcagga acggctgcct
    75361 tgctctgcct atttccccag aacaaaaaac tgaagcttag tattagaaaa agtcctaata
    75421 aaagactaat taggtatggc agaaaatacc gctctctcaa aaacgatttt cctttaatta
    75481 ataattcgtc taacattttt ttacctcatc tttttattcg taaatgatat ccaaaagtat
    75541 agtagtattg tcattttttg tgcttaaaag agttaagggt atcatcgaat atctttttta
    75601 gaaatgaaaa aagtgattaa gcattagcgg cttctttcaa tagaagacta atctcaatca
    75661 cttcttattt caggcacatg ttagccctca tgttcttaat ggcgatgttt atctggattc
    75721 caaacaaaac tagcaatata ggaaaataac atggttaata ataataccac caccaaaacc
    75781 aatcctaatg gtaaacggta gagataagtt aaagggttcc ttgctttgcc tggttggaaa
    75841 ggtgccaact cgtcatccat ccgatcaaac tctgcctgaa tacggtttgc cacctcagca
    75901 atcccttcat cattcatgcg tttaatatct gagacgtcaa tgggattccc aaaagtcatg
    75961 tcaacccgtt ctcccgctag taatcccttg accgacatag gcccctgata ggctgctggc
    76021 ataatcttga ccttagccaa tttagcaatc acagcgaccc ctcctttgac ctcttgcgaa
    76081 tgcctacttc cacttggaaa cataagaaga gaacgattgc tctttttgag catattaaca
    76141 gggtaacgaa tagcatctgg actcggtttg tcacgatcaa taggaaaagc accacacatt
    76201 ttaatccacc aagcaaagag acgatttgca aacaactctt ttttagccat aaaaataaac
    76261 tgcttagggc gtgctgcaaa tgccatgtaa actggatccc aaaaggttcg atggggtgct
    76321 accagaatat aattctcaga agcatctaac atcttttctt catgatggta gtgggcattg
    76381 ccattgacaa cccataataa aaagactact aaaccgcgta agtaagcgta aaacacaggc
    76441 ttctccttta atagaataat cttacttatt gtatcatgaa agttgacttt tcgaaagtca
    76501 aaatcactct tcaaacattc acctcaagcc tattttatgt taaaataaca ggtatgataa
    76561 aagcaatctt aaaagaaggc gaacgtattg atcaactctt ttcaagtgat gttggcatta
    76621 ttcaaaacaa ggatgtcttt agttactcta ttgatagcgt cctcttatcc cgcttcccca
    76681 agatgccttc caaagggtta attgtggatt tgtgctcagg aaatggggcg gttggcttat
    76741 ttgctagtac tagaaccaag gcagccatcg ttgaagtcga attacaagaa cggcttgctg
    76801 atatgggaca acgctctatc cagctcaatc aactggaaga ccaagtaacc atgatttgtg
    76861 atgatttaaa aaacctccta aaccatgtgc cacgttcagg agttgatttg atgctatgca
    76921 atccccctta ctttaaaagt cacgaaagtt ctaagaagaa cgtctctgaa cattatttac
    76981 tggctcgtca tgaagtgacc actaatttag aagagatttg tcagatagcc cgtcatgccc
    77041 ttaaatcaaa tggtcgtctg gcaatggttc atcgaccaga tcgattcttg gaaattatag
    77101 atagccttag agctaatggt cttgccccta aacgggtaca atttgtctat cctaaattag
    77161 gtaaatcagc taatatgtta cttattgaag caatcaaaga cggttctatt gaagggatga
    77221 ctattttacc tcctttagtt gtccacaagg aaaacggaga atacactgat catatttttg
    77281 agatttattt tggtgctgct tccaaaggaa aacctaatca tgaccactaa aaaagcttat
    77341 atgtatgtgt tagaatgtgc agataaaacc ctctacactg gttatacaac tgatttgaaa
    77401 aaacgcttag ctacacataa cgcaggaaag ggggctaaat atactcgcta ccggttacct
    77461 gtttctttac tttattacga agtgtttgat agcaaagagg ctgcgatgag cgctgaagca
    77521 ctctttaaaa aacgaaaaac aagaagccag aaattggcct atattgctac tcatcaaaaa
    77581 gaaaaaaaaa atcattgaga cttatcatct caatgatttt tttatgcttc actgtcttcc
    77641 acaggcacca attctttgat tggtaacttc aagacatctg atagaatcaa gggaaccact
    77701 tcaagggtta cttcggaata ttgaagccca aaccaacgca ttggactagc ggtaacatgt
    77761 ttaatgcttg ccttagtctg cataataaaa cgttcaaagt tactcaactg acgtgcattg
    77821 gagacccgtt cttctattaa aacaaagcga aaatcaccaa catcacgacc aggtgtgatg
    77881 gtatattcct gttcttgttt gggtaaacgg tcactttcca tcaaatcctg aacaatcgtg
    77941 cgcaaatagc gtggcacagt ctgtggcatt ctaaaaccaa gataaaggtt gactcgaacc
    78001 atataatccg ttcccatcat atctaccttg tacttagctg tataaggttc atcagttacc
    78061 tggacattta caaaccaata aacttgagcg cgttttggcc gcttgtctaa aatggagtat
    78121 aaaatagacc ggtcaatcat atgatcctgc atacgattgg ataggtagac aacatttgtt
    78181 tggtagaggt caaaacaaac gtcgtcacga agttgtttaa tctgctcctt gtaatcattc
    78241 aaattaagag atttcacata cttgaaaaca atccgtgtgc ccgcatgcca gataaacatg
    78301 acaaagacaa ttgcaagtgc caagataaca accgcatagc caccgtgcat aaatttgata
    78361 gctgaagcca agaagaaaat gaattctaca agggcaaaga aagccatcac taaatgagcc
    78421 aagatgggtc tcgttccttt cttgattaag taatacttta agaggattgt tgtcatcaac
    78481 atggtgatgg taatagcaag accataagct gcctccatgt gagctgatgt tctaaaaacc
    78541 aaaacagtac aagaggtcac tgcaaataaa atccagttaa tgacaggaat atacaattgc
    78601 cccaaatttg cccctgggta agtcacacga aacaaaggga aaattttcaa acgcatggct
    78661 tctgaaacca aggtaaagga gcctgaaata agagcctgtg aggcaataat ggctgctaag
    78721 gttgccaaac taacaaggta aacccttaat tgtgatggca cactagcaaa gaaagggttt
    78781 agttcaatac ctgagtgttt attcgctaaa atccacgcag cctggccaca gtaagacaac
    78841 acaatacaca tcttaacaaa gggccagctc acataaatat ttcctcgacc aacatgtcct
    78901 aaatccgaat aaagggcttc agctcctgtt gtcgcaagaa aaatggaccc caagataaaa
    78961 atcccacgat ggttttcagg actaaacagc aaatgcagag catagtaagg attgatagcc
    79021 ttgaaaattt ccagatgccc caacgtatta aaaaaaccac taacacctag aaaactaaac
    79081 cagataaaca taactggtcc aaaaatttta ccaataaaac ctgttccaaa ccgctgaata
    79141 ccaaacaaga ctattaaaat cactagagtt gtgataatga cattggtttg attttggtag
    79201 atgtgactca gaccaggaac ggctttcaag ccctcaatag ctgaagtaac tgttaccgca
    79261 ggtgtaagag ccccatcaga caaaagtgtt gcacctccaa tcatcgccgg aataatgagc
    79321 cacggtgaca ttttacgtac caaggtgaat aaagaaaaaa tcccaccttc atggtggtta
    79381 tccgctttta gagcaatcaa aacgtacttg attgttgtga ttaaggtcag tgtccaaata
    79441 attaaagaga ttgatcctaa aataaaggat tcagaaacct gattaacccc tccttgattt
    79501 tcaactagag actgcatcgt ataaaggggg cttgttccaa tatctccata aacaatacct
    79561 aaagcaataa taaaacctgc ttttgaagct ttgtcaaagg cagtaagatg gctatcagac
    79621 atcttatact cctcctaatt ttttaaaaat tatcacaaaa ataactgaaa ccattataac
    79681 agattccatt ataaaagcaa ctttttcaga aaattaaaaa gagctgactc tcatcaactc
    79741 tctttaagct tattcacctt tgtgacgaat cacaaaacca gtatttttag cacttgattt
    79801 tttctcttta ttgaaaaagt ctttactatt acgttttgat ttacgtttga aatcgcggtt
    79861 gccactgcca tcgtgaccat cacgcttatc acgtttttga cgacgacggt caccatcacg
    79921 ctcatctctg ttacggtcac cacgatagcc gccacggcga tcaccacggt tacggttgtc
    79981 acgtccacga ccacctttgc catttttatt gccgtgacca ccacccacat atttgaatgg
    80041 taatggtttt tcacgtgcaa tttcaacttc cggtaagcta tctggatctt gaaccgttaa
    80101 gctcaaaata tataaagcta attcttcagg agtgaattcg gcagccaatt ggacagcatc
    80161 gcctttgaat ttatcaaagt ttgaacgaat agtctcatcc gcaaagtcgc gttcaatttt
    80221 cttgagggct acttttttct tggcttgaaa ggcctcttca gcagttgctg gacgaagagg
    80281 tttcatctgt tttttcgtta agttctcaat cattgagagg tagcccatct catttggtga
    80341 gacaaaagtg atagactcac cagatttacc ggcacgacct gtacgaccaa tacggtgaac
    80401 ataactttct ggatcttggg taatatcgta gttataaacg tgggtaactc ctgaaatatc
    80461 aaggccacgc gctgctacat cagtggcaac aagaatatca atttggtcgt ttttgaaatc
    80521 acggataaca cgtaagcgtt tattttggtc aagatcacca tggattcctt cggcacggaa
    80581 accacgaagt ttcaagccac gtgtaatttc atcaactcgg cgcttagtcc gcccaaaaac
    80641 gatggataat tctggctggt taacatccat cagacgggtc atagtatcaa atttttcttg
    80701 ttctttcaca cgaacatagt attgatcaac attgacgttt gttaattctt tgttcttaat
    80761 ttgaacatgt tcagggtctt tcatgaattt aaccccgatt tgtttaatag gtgccggcat
    80821 cgttgcggag aagagcaagg tttgacggtc tgctgggaca cgactaataa tagcttcaat
    80881 gtcttccaag aatcccatgt taagcatttc atctgcttca tcaaggatta aggtttccac
    80941 atgatctaaa ataagagcct tgcgcttaat caaatctaac aagcgacccg gtgttcccac
    81001 gacaatgtgg gcacctgatt taagggcttt gatttgtttt tcaatacttg atccaccgta
    81061 aacagagcga accttaaccc ctttttcacg tccaaaacgg aacaattctt cttgactttg
    81121 tacagccaat tcacgcgttg gtgcaatgac caatgcttgg atgatatttt cgttagtacg
    81181 aatcttattc aaggttggta gaccaaacgc tgctgtttta ccagttcctg tttgtgcttg
    81241 accaataaca tccttccctt ctagtgcgag aggaatcgtc atttcctgga taggagatgc
    81301 tttctcaaaa ccagcggtaa caacagctga ttggatgtct tgtgataagt taaattctgt
    81361 aaatttcaat tgtttctctt ttctaaaaag gcagtgcgaa gctgccttat aaacctttta
    81421 attttcgtcg tttgattaac aacctaacta gtgtaacaca attagaatca aaaagatagg
    81481 aaataaggct aatataagca ataacacgct ttcacgatta tccgctaaat cataaatatg
    81541 cttacagttg tgaagatatc gttttttgat agaatcttaa atctgcaaaa gagataacta
    81601 gccactcatt tcttttaaaa agttgctcag taaattgatc tccaaaacgt tagactgttg
    81661 aaaatcatgt ttcgattaca ttttctcttc taaagtgaca tctgggtatt tgtctgcaaa
    81721 ccagcgaagg gcaaaatcat tttcaaatag gaaaactggt tggtcaaaac gatccttagc
    81781 taaaatgttt cggcttgagg acatgcgttg atccaaatca tcttctgaaa tccagcgaac
    81841 agtcttttta cccattggtg tcatcacaac ttcagcgttg tattcacctt ccatacgatg
    81901 tttaaagact tcaaactgca gttgacccac agcacccagc atgtattcgc ctgtctgata
    81961 attcttataa agctgaattg ctccttcttg tactaattgt tcaatacctt tgtggaagga
    82021 tttctgcttc ataacatttt tcggagaaac cttcatgaag atttctgggg taaaagttgg
    82081 taagggttca aattcaaatt tatttttccc aactgttaag gtatccccaa cttgataagt
    82141 tcctgtatca taaaccccga taatatcccc agcaacagca ttcgtcacat tttcccgtga
    82201 ttctgccata aattgagtaa cattggagag cttagcgcct ttgccagtgc gtgtcaaatt
    82261 aactcccata ccgcgctcaa attcaccaga aacaatacgc acaaaagcaa tacggtcacg
    82321 gtgtttaggg tccatgttag cttgaatttt aaagacaaaa cctgaaaaat ctttagctaa
    82381 ggggtcaaca acattacctt ctgtagtctt gtgaccatga ggttctgggg caaactccaa
    82441 gaaagtatca agaaaagtct gaactccaaa gttcgtaagg gcagagccaa aaaagactgg
    82501 ggttaggtca ccatcaagaa tagcttgttc tgaaaagtca ttacctgctt cttgaagaag
    82561 ttcaatatct tctttgactt gttcataaaa gggattattg gcaaacagct gatcaccgtc
    82621 ttcaatactt gcaaaacgct cgtctccctt atagagttct aaacgtttat tatgtaaatc
    82681 atataagccc tcaaaggcgc gtcccatacc aatcggccag ttcatcggat aagaagcaat
    82741 ccctaaaact tcttctaatt cttccaagag ttctaaaggc tcacgcccat cacggtccaa
    82801 tttattaata aacgtaaaaa ccggaatatt acgatgctta acaacttcaa aaagtttttt
    82861 cgtttgcgcc tcaatacctt tagccgaatc tacaaccatg acagccgcat ccacagccat
    82921 taaggtacgg tatgtatctt ccgagaaatc ctcatgtcca ggtgtatcca aaatattaac
    82981 acgtttaccc gcgtaatcaa attgcataac agatgaagta acagagatac cacgttgctt
    83041 ttcaatatcc atccagtcgg actttgcaaa cgtacctgat tttttccctt ttactgtccc
    83101 tgcttctcta atttcaccac caaaatataa tagttgctca gtaatagtcg tcttaccagc
    83161 atccgggtga gaaatgatgg caaaagtacg gcgtttttta atttcttctg taagtgacat
    83221 tcttttttcc ttgtatagta aaatggcaga gcttttctct gagttatttt cgttaggtat
    83281 tacttgttta tcaaaagagt tgggctacat tgggtttctc catatacgat tagcctctaa
    83341 agttcttcaa aactggtatt ataacttatc ttgggctatc aatgagtgtc ttttttaaaa
    83401 aaatcgagcc tggaaatcat cccagactct tcttattata gctgatttta agtgcttttt
    83461 caacgaccta cttttcttta gagaaagcaa gtgccagctg ttgagcttca ccaaatttaa
    83521 ggtaaaaata ttcggttatt ttaaccataa aagtcaagcc acttgtaacg atcacaaaat
    83581 taagtagcaa atgacgcgta tgaatcactg gaatatccat cacaaaacca taatttcctt
    83641 tcgtggctaa actgaccaac agaagaagaa agttaacagt tgctaaatag cgtactactg
    83701 atagcagtct taactgactg gcatcgtaaa aacgcaagag gtaaatcaaa ccattcacta
    83761 acaaagcata atgaccaaga taaaacgaga catttgctac atgccataat ctaaacggat
    83821 aaagatctgg cgataaaagt gcaaggaatg ttccacctat ccccaaaacc ataaataatt
    83881 gcttaaactt gttacgatca ggtagaaaaa agatagctaa catagcgatg cgacaatgat
    83941 acaacggcaa agcttcatct aaaggaaacc cccttaacac gtaccatgtg tacaagccaa
    84001 tcacctgaga taactgtaaa aacaagaaaa aatatcgata agattttaac ctatatgctt
    84061 gaaaagtcaa aaaaacaagc aaaagcgcta tcaagagtga cgacaagtaa aagataagtg
    84121 aggtatgagg cagtccgatg gggtcaattg caaaaaaatc cataatcgtc cctttctata
    84181 ttttttcatt ataccttaat cttcatgaga gaacaagact ttatctgaaa gttttataaa
    84241 aatcaaggct gatagctgtc acaattcttg tcagtcacta atcgatccac taacttttct
    84301 agcgacatcg agtggctgcc ttttaaaaga atttgatcaa agggattaag aatgttttga
    84361 acatattgtg ccatggcttc aaactggtct tcttgttcag tttttaaaaa ataatgtact
    84421 tgctcagcag gataaacctg acttgctaac cgtgctaatt ctttaatatg atccccataa
    84481 aaaacaagct gatcaatatt acctgatgtt aagctgtcaa ttaactgaga atgaagtatc
    84541 actgaatcct ttccaagttc tttcatatct gctagcactg caatcttttt tcctccgggg
    84601 ttctttgcta tgttagcaaa tgtttctaaa atcagacgca tggctgttgg gttggcattg
    84661 tagacatctg ataaaatatc agcaccattg gctgcttttt tccactccgt acgattacct
    84721 gtcaacgtca cagtctgtaa agcagctata atatcttcgt ctgttactgc caatagtttt
    84781 cctacatagg ctgctaccat agcattggtc gcgttgtatt ttcctggtag aggtagggac
    84841 acaggtgttg ctaacacatt tgttgtaaac gttaagctat ctttgtcttc ttgaatacca
    84901 gtaacgtcaa tttcctgctg atttccaaaa cggataacca tctgattttc tggaagatat
    84961 gggtcaataa tcggatctcc cggagcaatt aaaatcccat ctgaattcat gccgtcaaca
    85021 atctgcattt tgccttgggc tattttgtct cggcttccaa aatattctaa atgagcttcg
    85081 ccgactaagg ttaaaactgc aatacgaggc cttgcaattt cagacagaag acgaatatct
    85141 cccatgtgat cttgtcccat ttcaagaaca attttttccg tatcgtcagg catgtggaga
    85201 acggtgtaag gcaaaccaat ctcattattg taatttcctt gcgttttgta agttttgtaa
    85261 gtggttgata ggacagctcc tatcatatct ttggtggaag ttttaccatt tgagcctgtc
    85321 acagcaataa catccacgcg catcttatca atataataat gggctagctt ttgaaaagct
    85381 tttaggcagt cttcaacaag aaggtgaggt ttccccggca attctttttc tgaaaaagta
    85441 gcgacagctc cattttgaaa ggctaaatca ataaactcat gaccatccct ttgacctttt
    85501 aagggtaaaa agaggtctcc ttttgtaatc tttcggctat caaattcaat gtgatgcaga
    85561 ggaacgtcgt ctaagtcaga cacattattt tgggcgtcaa ctattttagc cacttcgtgt
    85621 aaggttaatt tcattttgtt ttctttctaa gaacactagt atttacgatg tcctatctat
    85681 tatagcacaa aacattagaa aaatttctaa aatgtcaaac tcccttaatg gctctactat
    85741 aaagagcaac aaaaaaagga cgaacgtcac atcttgacga tgtttgccgt tccatccaag
    85801 tcaatgttta ttcatctcat aggtttaaat caggtggctc tcacgctggt caaacatttc
    85861 ttgtgccagt gtcaccagct cttcaatcaa atctggataa gccaattcca tattttccca
    85921 taagagtgga tacatagacc attgggtaaa tcctggcatg gtgtttaatt cgttaaggta
    85981 aacctgtccg tcttgggtca agaaaaagtc acaacgagac aacccacaac cacctaaggc
    86041 tttaaaggct acttcagcat aagaacgcat ttctgtcaca atactctggt ctacatctgc
    86101 tggaatggcc atcgtaatct tattgtcaac atattttgct tggtagtcgt aaaaatcaac
    86161 gtccttgatt acttctcctg gtagagttga tttaacctta tcatttccaa ggagaccaac
    86221 ttcaatttct ctggcaacca cgccttgttc aatcaagaca cgactgtcat aggtcagggc
    86281 taactgaatc gcttttctta attctacttt tgtttgggct ttggaaatcc ccacagaaga
    86341 acccatatta gctggtttta cgaagatagg aaaagtaagt cttgctaaag tttcaactaa
    86401 acaagcctcc aaatcttgtc cgtcaatata aacagtatag gcaacttgtg gaattccaat
    86461 tgattctaag acacgtttag tagtaatttt atccatagct atgctagaag acatgacatt
    86521 agtccctata tatggcattc taagcacttc taagaaacct tggatagagc catcttctcc
    86581 cataggtcca tgtaatacag gaaatacaac tgcaccttct tcatagatat cacttggttt
    86641 tattttttga gttagctcta tcgtctcatt tgtcatcaag cgttctgatt ccgatggctt
    86701 ttctgaaaat tgctgagttt tgataaattg gcccatctga gtaataaaat aagtttttac
    86761 taagaactta tcatagttga ctgctcgcat cacactctct gctgaaagca ctgagacttc
    86821 acgttctgct gagcggcctc cgtataatag aactaacgtt tgtttggaca tagctaacct
    86881 ttcttatctg aattgaatgt ttttttatta taacaaaaag atgtagcctt ttcaaaacct
    86941 ctctttgcga gtaaaggcac caacatgatc attaaagttc agtacgattc tcaatagctc
    87001 tcaataatgt tacttcatca gcatactcaa tatctgaacc tactgcgaga cctcttgcca
    87061 aacgagttac cttaatcccg gctggtttca agacacgtga aatatacatg gacgttgctt
    87121 ccccatctgc tgtggcattg gtagctacga taacttcgct caccttacca tccattagac
    87181 gggtaattaa acttttaagg ttgatgtcat ctggccccac accattcata ggcgaaatca
    87241 agccgtgaag cacatgataa tagccatgat actcttggat tttttccatg gcagaaacat
    87301 ctttagcatc ttctactacc agaatggtcg tctgatcacg actcgtgtct gtgcaaatgt
    87361 gacaaggatc gtcatcggta aggtttccac aaatcgaaca ataggtcagt tctcttttag
    87421 ctgctaataa gtttttagca aaatcattga catcttcatt tgacattcca atagtataaa
    87481 aggctaatct cgtcgccgtc ttgataccaa ttcctggaag tttagagtaa ctgtcaatta
    87541 actttgcaat gggtgttgga taaagcacta agttctcctt tattgttttc catatatcgc
    87601 cacataaagc gctctcacat ctttgccgat atattcgtaa tatgtggata cataacagca
    87661 accgcaatat tatcttcgtt atttgtatta taagctacta catttaagtt gtaagttact
    87721 aaggtctgat ctgaattgtc tgtgatacaa gtctcagcag ttccaatttt agcgtgaatc
    87781 gtgacagaac cgtttggatt agccaagtaa aaactttttt actcgacttg ttaccttggc
    87841 cttgggatat ttggcttttg ttttttgatt catgttactt ttttagaaac cgcaaaccat
    87901 ccttatgata taagtttata ggaattgttt cattccatgc agaaatgatg tttactcaat
    87961 tgactatgct atttttctca acaatagtgc ataaagcgaa ctcatggtta tctttaagct
    88021 ttcatgctac actttcttca ctaaaagtgt attaccaaaa gcattattaa gaaatctcta
    88081 agcacaaacc ataagacagt ttgtacgcct gatgaatctg ttgctgcatc actgtccact
    88141 ttttacccta tcaaggctat ttttgaaaga caactaaatg atctgcatta tttggggaac
    88201 tactcccata gcaaattctt tttacgcatt ttttgggaat actccttttt tagggaataa
    88261 actaaccatt atttagctaa attttttaaa cttcgcttct tattttacca taaattataa
    88321 aaagaagact gagaatagga cgccctcagt ctaaaaaaat attttctcat tgagttttac
    88381 tcttttgcgg atgatagtaa actttaaaat ataaaaaact aacaaaaatg gctccaccga
    88441 taatattacc actatagaca aaaataaaat tagtggcaaa atccaaccat gttgctcctc
    88501 cttcaaaaat agcagcagga atgacaaaag catttgctac actatgctga aaaccaaggg
    88561 ctacaaaggt catgacagga aaccaagtac caaggaattt accagcagca tcatttgccc
    88621 catagcatag ccacaaggcc aaaccaacaa accagttaca accaattcct gatactagtg
    88681 cctgcaaagg gctcgctgct attttagcat gggccacctc aatcacttct tctttaaaaa
    88741 taccagctga tgttaagcct agaaaatgac caaacacaaa agctacaaaa acagctccaa
    88801 tcacattaaa caaggtaatg ataagccaat tcttggcaag ctcgctaaac ttaatttttt
    88861 tggccaacaa agctgcagaa acagccatca tgttccctgt aattaattct ccacccgcca
    88921 ttaaaataat aattagacca atcggaaaag cacaagctcc tacgatactg gaaaaagcac
    88981 caaaagtttc taaaccactg gcggcaattc tcacgtagag taaataacca aggctaatca
    89041 tcgctccacc aataaagcct aagatagatt tagccaaaaa agttttggta accttatgtt
    89101 ccccaatatg aatagttgct tctaaaatct gttctggtgt tttcatgata tctccttttg
    89161 ttactgtatt cacaaacaca cactttagta tatcaatttt cctaaaaaat gcaagccctt
    89221 tcaacaagaa agggctcgtc attatcatat aactatctct attttagtct taggcattta
    89281 tggtgggaag ttttaagttt tttgctaaaa aacgccatag aactaaagca agatagaaat
    89341 ccaatatgcc atgaataagc gaacctaagc caatcaagcc tagcatagac caaaaataag
    89401 acatagaagt tgctgtggtt gctgttaaaa tatagacaac taaaaattca gccaagccat
    89461 gaatgacatt aatgaaaaac gcaaaactaa aacattttac tgccgatgtc atcagttgtg
    89521 gttttctact taaccaccac gctgccaaaa tagcaaacaa taaatgagag agtgctctta
    89581 aaacaataat taaaggaagt ccagctaata aaaaacctaa tgtggtacca agagcgacca
    89641 aaattgctac tggaatcgac ataaaaatag ccaaaaacaa aggaacatgg ctcgccagag
    89701 taaaggaagc tggtccaata ataagcttaa gaggcatgat tatcggaatc aaaatcgcaa
    89761 atgcgaccaa aatagaggta taagctatta gttgtgttgg ttttttagtc attttatctc
    89821 cttttcaaaa atagtatacc ttaaaaacca ataactatca agacacctgt atcttttggt
    89881 atttttaaac gataccttgt tgctgataaa taatcaatag aatattttag catggtattc
    89941 ataacaacca tcaatggcat aatatactgt agttatattc ctttgtataa gatacctgct
    90001 aattctaaat catgcttgat agctaaaaag gcttcttgac taggacacga aattaagtga
    90061 ctatgtagtc cttctgtcaa cgaagacaat aactctgctt tagattgact gagtttggac
    90121 atgaaattag ttacatcaga gtgtgtctta atatttaaag gggctgttat cataccgtaa
    90181 ataggatgtt ctacctctac cgtcgtaata atcccttgat gagctaaaat aatttctaat
    90241 tcttttttag tttcttctac attatgttgg cacacaatac gtgcacaaaa ttggtgacta
    90301 taaagcgctg ttgacataat ataacctttt ggagtcgaaa taatatcaat ctgctgagct
    90361 cgaagaagag ctatatctcc aacaattact tggcgactca ctcctaataa cttacctaaa
    90421 cgagtagcag atacagcttt ttgttcacta tttaagcact caataatttt ttgacgacga
    90481 tcttctgctt tcataatcta tctatccttt tttatttcta tcatatcata tttttaagca
    90541 gggttttctt tcttcttagg atatagaacc caaaaaacca gaccaaagtc tggtttttaa
    90601 gttattcacc accaaggtag tattctttaa caatgttaag tttttcatct aattcaaaaa
    90661 caagtggtgg gaagtttgga atttccacat ccatgatttc gtcatctgaa agacctttaa
    90721 tgtgtttcac aagagcgcgg attgagttac catgtgcacc aacaaagacg tttttaccgt
    90781 caagaagagc tggagcaatt ttttcttccc agtaaggcat tgcgcgttca agagttactt
    90841 ttaagttttc agcatctgga ataagggctg ggtcaagatc agcataacga cggtctttgt
    90901 gtgctgaata ctcatcatct ttagccatag ctggcggcaa cacgtcgtat gaacgacgcc
    90961 agatatgaac ttgttcatca ccaaattgtt ctgcagcttc agctttgttt ttgccagtca
    91021 aagcaccata gtgacgctcg ttcaagcgcc atgatttttc agttggaacc cacaattgac
    91081 ctgcattttc aagggcaagg ttagttgttt tgatagcacg tgtcaatact gaagtgaaag
    91141 caaggtcaaa ttcaatacct gcttctttga tcaatttacc tgcatcaatc gcttgttgtg
    91201 tccctttttc tgaaagatca acatctgccc aaccagtgaa gaggttagct ttgttccatt
    91261 ctgactcacc gtggcgagcg aaaaccaatt ttaccatgag ttaatatctc cttttaattt
    91321 aaaggttgct acctttttac aattcctatt ttacaaaaaa tatagcaaaa aagctagtct
    91381 attctgactt tattgaaaat cataatgtga ctatcatgaa aatttcaaat gttcgtcaat
    91441 aacagtaata tatttacatt tttgtgaaaa tagcttgcta ttattcatgc ctagtggtag
    91501 aatagaaaaa atttgtctaa aatatggagg aaataatggt ttctactgct acacaaattg
    91561 gtcatttctc ttttgataac tgtttgatga atgctgctgg tgtttactgc atgacaaaag
    91621 aagagcttat ggaggttgaa aagtctcaag ccgcttcctt tgtcaccaaa acagggacgc
    91681 ttgaagttcg tccaggtaat ccagaacctc gctacgcaga tactcgtctt ggttctatca
    91741 attcaatggg actccctaat aatggttttc gctactactt agactttgtc agtgatcttg
    91801 ccaaaaccgg gcaacataaa cctcactttc tctccgttgt cgggctatct cctactgaaa
    91861 ccgaaaccat tttaaaagcc atcatggctt cagattatga gggtctagtg gaactaaacc
    91921 tttcttgccc taacgttcca ggaaaaccac agattgctta tgattttgaa accactgatc
    91981 aacttctaga gaacatcttt acctattaca ctaaacctct tggtatcaaa ttacctcctt
    92041 attttgacat tgtgcatttt gatcaagcgg ctgcgatttt caataaatac cccctttcct
    92101 ttgttaactg tgtcaattct atcggaaatg ggctggtcat tgaggatgaa caagtcctca
    92161 tcaagcctaa aaatggcttt ggtggtatag gtggagatta catcaaacct actgctctag
    92221 ccaatgtcca tgcgttttac aaacgcttaa aaccttctat ccacattatt ggtacagggg
    92281 gagttaaaac aggacgcgat gcctttgaac atattctttg tggcgccagc atggtccaaa
    92341 ttgggacagc ccttcatcaa gaagggccag ctgtctttga acgggtcact aaggaactaa
    92401 aaacgattat ggtagaaaaa ggctaccaaa gcttagacga ttttcgtggg aacctacgtt
    92461 acaaagatta accttaatag tcaaaaaagc ttggaaatgt gcactttgta cactttccaa
    92521 gctttttaaa atgggaattt ttttgaaggg acagcgtcac tttctttgga ctgtctttgc
    92581 tggttgtttg attcaacttt tcttttttgc ttgcgctcaa attgctgata aaaatagaaa
    92641 aatagaatga ttttaattat tgaaaataca gctaaaccaa tgatcataat agtaaacata
    92701 cggcggtttt ctctttcata agtcttacta ttattataaa cactttcaag ttttcaagca
    92761 agtttctaaa ttatttaaaa gaaagtaaac gcaagccatt taaaatcact aaaatcgttg
    92821 agccttcgtg tccaacaaca ccaagcggca agttaactac ctgaaaaaca ttggctaaaa
    92881 tcaataaggt aatcacagat aaggcaaaaa caatattttg tttgataatg gtcttcattt
    92941 tgcgggaaag ttgaatcgaa aatggaatac gagtcaagtc atccataatc acactgtctg
    93001 cactttccat tgcaatatct gttcctgatc caatagcata agaaacatct gcttgagcaa
    93061 gggcaggagc atcattaata ccatctccta ccatggccac aaaaccatat ttagtcttta
    93121 attctgctaa cttagccacc ttatcttgag gcatacagtt ggctaccact tcatcaatac
    93181 caagtttttg tgccacataa ttggcggttc gttcttggtc acctgttaac atgactgttt
    93241 tgattcccat ggcatgaaga gacttaatag cacgttttga ttctattttg atatcatcca
    93301 agagggcata gtaagctatc aattgatggt cacgtgaaac aaagattagg gttttccctt
    93361 gattttcttc cacttgaata gtttcttcaa aagctgatag gtcttgaacc ttttccaaaa
    93421 tgaaggtttt cttgccaatt cgccattctt gcccttgata gaagccctga aaacctttcc
    93481 cagaaatttc ttctaagtgg tcaaaggtca gtggctccaa tttttcagtg tattcaagaa
    93541 gggctttaga aataggatgg gtactagcag tctctgctcc ttttaccagt ctattcacga
    93601 gcaactcatc ttccaaataa tgagcattca caacagaagg ttttccttgg gtgagcgttc
    93661 ccgttttatc catgacaaca gccttaatat ctcccatgtt atcgacaata tcccctcctt
    93721 tgataatcaa tccctttctg gctgcacgag aaatagcagc caagctagca ggtgtggaac
    93781 tggcaattag ggcacatggt gaagctactg ttaagagaat catccctcgg taaaaagcag
    93841 ccaaccaagt ccaaaaaagc acaaagtggc taaagaggat aaaggcagga ataaggacga
    93901 gcacaaattt gacataacca tcttctaagc tttcgataaa ggtggcagtt ttgcttttct
    93961 tttcttgggc agattccacc agattaataa tcttggcaaa gagagtatcg tcattttcaa
    94021 tagtaaccaa catatctatg gtttgtcctt ggttaatggt tcccccaatc agatcctggc
    94081 cttctgcctt atcaacagtg ataggctcac cagtgaccat agattcatca aattgaccaa
    94141 aagggctaag caactgcccg tcaattggaa cagcttcgcc tttacgaact tgtaaacggt
    94201 caccaacact caaggatctg gtctcaactt ctaaaatatg gccatcttct tggtattgac
    94261 gagctgtatc tggcgtcaag gacatcaagg ctgaaatagc atccttactt ttttccatgg
    94321 ccatttcttc aagcgtattg gacaacgaaa agataaaaat aagcagagca ccctccagcc
    94381 aatagccgat aattccagca ccgatagctg ccaaaatcat caaaatatcc actgacaagt
    94441 gtttgttctt caccaaatcc aatatacccg tttttgcaga cgcatatcct ccaatcaaga
    94501 aggctgtaat gaaaatagcg gaagccagtt gtggaaatga gtgtaaaaag gctaggccaa
    94561 ttattattaa taccaaacac gctaaagtct ccatcaaatg aagatggtct gccatccatt
    94621 gtctgattgt catttttagt tccctcacaa ttaaaagtta ttcaatcttt aa
//
LOCUS       DAUGSW010000004        89780 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUGSW010000004 DAUGSW010000000
VERSION     DAUGSW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 89780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89780
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.004"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(55..570)
                     /locus_tag="VIB18_000295"
     CDS             complement(55..570)
                     /locus_tag="VIB18_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEQ8765330.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYLLQIATIFLFETHGDRWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            651..1259
                     /gene="recU"
                     /locus_tag="VIB18_000296"
     CDS             651..1259
                     /gene="recU"
                     /locus_tag="VIB18_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEQ8765331.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            1246..3411
                     /locus_tag="VIB18_000297"
     CDS             1246..3411
                     /locus_tag="VIB18_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8765332.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIIDVTNGHVIAQLGGRNQDENVSFGINQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNGSHPSTDDKKTTH"
     gene            complement(3878..5215)
                     /gene="pepC"
                     /locus_tag="VIB18_000298"
     CDS             complement(3878..5215)
                     /gene="pepC"
                     /locus_tag="VIB18_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEQ8765333.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQY"
     gene            complement(5400..6224)
                     /gene="nadE"
                     /locus_tag="VIB18_000299"
     CDS             complement(5400..6224)
                     /gene="nadE"
                     /locus_tag="VIB18_000299"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEQ8765334.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETGDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVAALQEAGIEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(6221..7681)
                     /locus_tag="VIB18_000300"
     CDS             complement(6221..7681)
                     /locus_tag="VIB18_000300"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEQ8765335.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLAEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMTLIDNIRKDTHGKSDLK"
     gene            complement(7852..9231)
                     /locus_tag="VIB18_000301"
     CDS             complement(7852..9231)
                     /locus_tag="VIB18_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8765336.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPNWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(9400..10317)
                     /gene="trxB"
                     /locus_tag="VIB18_000302"
     CDS             complement(9400..10317)
                     /gene="trxB"
                     /locus_tag="VIB18_000302"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEQ8765337.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIKGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTSMVKNLEITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFSS"
     gene            complement(10381..10605)
                     /locus_tag="VIB18_000303"
     CDS             complement(10381..10605)
                     /locus_tag="VIB18_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEQ8765338.1"
                     /translation="MLVEIFSLYVKGLILSSLTMMLICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(10709..11452)
                     /locus_tag="VIB18_000304"
     CDS             complement(10709..11452)
                     /locus_tag="VIB18_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765339.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            complement(11452..12255)
                     /locus_tag="VIB18_000305"
     CDS             complement(11452..12255)
                     /locus_tag="VIB18_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8765340.1"
                     /translation="MTSVFLTSGWAFYDHLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(12450..13793)
                     /locus_tag="VIB18_000306"
     CDS             complement(12450..13793)
                     /locus_tag="VIB18_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8765341.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            complement(13951..14961)
                     /locus_tag="VIB18_000307"
     CDS             complement(13951..14961)
                     /locus_tag="VIB18_000307"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEQ8765342.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(14963..17218)
                     /locus_tag="VIB18_000308"
     CDS             complement(14963..17218)
                     /locus_tag="VIB18_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8765343.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGATLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(17222..17545)
                     /gene="ftsL"
                     /locus_tag="VIB18_000309"
     CDS             complement(17222..17545)
                     /gene="ftsL"
                     /locus_tag="VIB18_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEQ8765344.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(17550..18563)
                     /gene="rsmH"
                     /locus_tag="VIB18_000310"
     CDS             complement(17550..18563)
                     /gene="rsmH"
                     /locus_tag="VIB18_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEQ8765345.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKTAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(18775..19017)
                     /locus_tag="VIB18_000311"
     CDS             complement(18775..19017)
                     /locus_tag="VIB18_000311"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765346.1"
                     /translation="MTNEREKEEAKVTLEELLHQIQVIHLELKIVRNWGYFFFFFGDG
                     MLVSWIKRRNNEQGQPIINRLTSYSSKLPKIAGRRR"
     gene            complement(19037..20287)
                     /locus_tag="VIB18_000312"
     CDS             complement(19037..20287)
                     /locus_tag="VIB18_000312"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEQ8765347.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTF
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     YTGHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(20280..21101)
                     /gene="proB"
                     /locus_tag="VIB18_000313"
     CDS             complement(20280..21101)
                     /gene="proB"
                     /locus_tag="VIB18_000313"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEQ8765348.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            complement(21166..22794)
                     /locus_tag="VIB18_000314"
     CDS             complement(21166..22794)
                     /locus_tag="VIB18_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765349.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVVQTPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     EFMYRRDYRLLDLKWQDMTQLFTRGDGQWLTMGLIFGNLIVAGVLGFGAVIIANIIQQ
                     PLLISILLSCLILMVLGIAHLWIQKTFWKSLERL"
     gene            complement(22799..23533)
                     /locus_tag="VIB18_000315"
     CDS             complement(22799..23533)
                     /locus_tag="VIB18_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765350.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPHKDLESIYLELAGRKAQEEG"
     gene            complement(23567..23833)
                     /locus_tag="VIB18_000316"
     CDS             complement(23567..23833)
                     /locus_tag="VIB18_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8765351.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            complement(24026..26011)
                     /gene="tkt"
                     /locus_tag="VIB18_000317"
     CDS             complement(24026..26011)
                     /gene="tkt"
                     /locus_tag="VIB18_000317"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEQ8765352.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     SGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(26229..26873)
                     /gene="fsa"
                     /locus_tag="VIB18_000318"
     CDS             complement(26229..26873)
                     /gene="fsa"
                     /locus_tag="VIB18_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8765353.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(26999..28498)
                     /locus_tag="VIB18_000319"
     CDS             complement(26999..28498)
                     /locus_tag="VIB18_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8765354.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(28488..29834)
                     /locus_tag="VIB18_000320"
     CDS             complement(28488..29834)
                     /locus_tag="VIB18_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8765355.1"
                     /translation="MTLTTKTIHVIGASFAGLTFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDADLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(29943..30644)
                     /locus_tag="VIB18_000321"
     CDS             complement(29943..30644)
                     /locus_tag="VIB18_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8765356.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            complement(30646..32484)
                     /gene="glpO"
                     /locus_tag="VIB18_000322"
     CDS             complement(30646..32484)
                     /gene="glpO"
                     /locus_tag="VIB18_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEQ8765357.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGHQEG"
     gene            complement(32500..34026)
                     /gene="glpK"
                     /locus_tag="VIB18_000323"
     CDS             complement(32500..34026)
                     /gene="glpK"
                     /locus_tag="VIB18_000323"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEQ8765358.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            complement(34386..34778)
                     /locus_tag="VIB18_000324"
     CDS             complement(34386..34778)
                     /locus_tag="VIB18_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEQ8765359.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDEKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(34905..35162)
                     /locus_tag="VIB18_000325"
     CDS             complement(34905..35162)
                     /locus_tag="VIB18_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEQ8765360.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(35316..37355)
                     /locus_tag="VIB18_000326"
     CDS             complement(35316..37355)
                     /locus_tag="VIB18_000326"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEQ8765361.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQCVIVDAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGSFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYAFLAGEDAAVATAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYANKADVMNFIRARVDKMMGKAAPKDIREAVLESSTFVVPEMLAAAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQSLKNNRLAILSDLVSKAKTIAAFNQLNTK"
     gene            complement(37733..38650)
                     /gene="glyQ"
                     /locus_tag="VIB18_000327"
     CDS             complement(37733..38650)
                     /gene="glyQ"
                     /locus_tag="VIB18_000327"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8765362.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDGE"
     gene            complement(39022..39555)
                     /locus_tag="VIB18_000328"
     CDS             complement(39022..39555)
                     /locus_tag="VIB18_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEQ8765363.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(39687..40526)
                     /locus_tag="VIB18_000329"
     CDS             complement(39687..40526)
                     /locus_tag="VIB18_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEQ8765364.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLGRLGLAYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKTNEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTPEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            complement(40652..41800)
                     /gene="nagA"
                     /locus_tag="VIB18_000330"
     CDS             complement(40652..41800)
                     /gene="nagA"
                     /locus_tag="VIB18_000330"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEQ8765365.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(41918..43549)
                     /locus_tag="VIB18_000331"
     CDS             complement(41918..43549)
                     /locus_tag="VIB18_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEQ8765366.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADDKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            43751..44473
                     /locus_tag="VIB18_000332"
     CDS             43751..44473
                     /locus_tag="VIB18_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765367.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSYP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQKQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(44602..45444)
                     /locus_tag="VIB18_000333"
     CDS             complement(44602..45444)
                     /locus_tag="VIB18_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8765368.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            45737..46294
                     /locus_tag="VIB18_000334"
     CDS             45737..46294
                     /locus_tag="VIB18_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8765369.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(46330..47154)
                     /locus_tag="VIB18_000335"
     CDS             complement(46330..47154)
                     /locus_tag="VIB18_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8765370.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(47156..47773)
                     /locus_tag="VIB18_000336"
     CDS             complement(47156..47773)
                     /locus_tag="VIB18_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEQ8765371.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLMARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(47970..48947)
                     /gene="lacD"
                     /locus_tag="VIB18_000337"
     CDS             complement(47970..48947)
                     /gene="lacD"
                     /locus_tag="VIB18_000337"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8765372.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVKANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(49097..49436)
                     /locus_tag="VIB18_000338"
                     /pseudo
     CDS             complement(49097..49436)
                     /locus_tag="VIB18_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560885.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(49446..49961)
                     /gene="lacB"
                     /locus_tag="VIB18_000339"
     CDS             complement(49446..49961)
                     /gene="lacB"
                     /locus_tag="VIB18_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8765373.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(49976..50401)
                     /gene="lacA"
                     /locus_tag="VIB18_000340"
     CDS             complement(49976..50401)
                     /gene="lacA"
                     /locus_tag="VIB18_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8765374.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(50659..52110)
                     /locus_tag="VIB18_000341"
     CDS             complement(50659..52110)
                     /locus_tag="VIB18_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEQ8765375.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHNHLPVLVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFIAIYLGLFAWYANQMKARNAEYAKTMT"
     gene            complement(52136..52441)
                     /locus_tag="VIB18_000342"
     CDS             complement(52136..52441)
                     /locus_tag="VIB18_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8765376.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPTVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            complement(52434..52907)
                     /locus_tag="VIB18_000343"
     CDS             complement(52434..52907)
                     /locus_tag="VIB18_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8765377.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     LFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            53144..53914
                     /locus_tag="VIB18_000344"
     CDS             53144..53914
                     /locus_tag="VIB18_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8765378.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            complement(54118..54321)
                     /locus_tag="VIB18_000345"
     CDS             complement(54118..54321)
                     /locus_tag="VIB18_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEQ8765379.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGQAKVT
                     GRPLTFLLKRALKDTKFELHKWS"
     gene            complement(54335..56566)
                     /locus_tag="VIB18_000346"
     CDS             complement(54335..56566)
                     /locus_tag="VIB18_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEQ8765380.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFMQPDWYPFIYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGQAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATDVRVWRSSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLI
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNAALMGILGIDLSCVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(56566..57000)
                     /locus_tag="VIB18_000347"
     CDS             complement(56566..57000)
                     /locus_tag="VIB18_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEQ8765381.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNLLTSYREGRAYIYQALLDETLVQKEALATVLDGICQRQHTRLLLERLYDL
                     PMTLEEIEAFQELLEVKKENAVLEVPCNCLPGQCHCQKKETY"
     gene            57172..58161
                     /locus_tag="VIB18_000348"
     CDS             57172..58161
                     /locus_tag="VIB18_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8765382.1"
                     /translation="MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEI
                     PEYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTPQ"
     gene            complement(58292..58642)
                     /gene="rbfA"
                     /locus_tag="VIB18_000349"
     CDS             complement(58292..58642)
                     /gene="rbfA"
                     /locus_tag="VIB18_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEQ8765383.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELDNKS"
     gene            complement(58848..61709)
                     /gene="infB"
                     /locus_tag="VIB18_000350"
     CDS             complement(58848..61709)
                     /gene="infB"
                     /locus_tag="VIB18_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEQ8765384.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQISKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSNVRVIRDSVVIFDGKLTSLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(61729..62031)
                     /locus_tag="VIB18_000351"
     CDS             complement(61729..62031)
                     /locus_tag="VIB18_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEQ8765385.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAVADAGFSKKMRTLME"
     gene            complement(62024..62320)
                     /locus_tag="VIB18_000352"
     CDS             complement(62024..62320)
                     /locus_tag="VIB18_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEQ8765386.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(62336..63493)
                     /gene="nusA"
                     /locus_tag="VIB18_000353"
     CDS             complement(62336..63493)
                     /gene="nusA"
                     /locus_tag="VIB18_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEQ8765387.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV"
     gene            complement(63668..64204)
                     /gene="rimP"
                     /locus_tag="VIB18_000354"
     CDS             complement(63668..64204)
                     /gene="rimP"
                     /locus_tag="VIB18_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEQ8765388.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(64312..64398)
                     /locus_tag="VIB18_000355"
     tRNA            complement(64312..64398)
                     /locus_tag="VIB18_000355"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(64362..64364),aa:Ser,seq:gga)
     gene            complement(64463..65098)
                     /gene="trmB"
                     /locus_tag="VIB18_000356"
     CDS             complement(64463..65098)
                     /gene="trmB"
                     /locus_tag="VIB18_000356"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEQ8765389.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            complement(65098..65889)
                     /locus_tag="VIB18_000357"
     CDS             complement(65098..65889)
                     /locus_tag="VIB18_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEQ8765390.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            complement(65953..66987)
                     /locus_tag="VIB18_000358"
     CDS             complement(65953..66987)
                     /locus_tag="VIB18_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765391.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFVLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERAYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNMLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            complement(66990..67715)
                     /locus_tag="VIB18_000359"
     CDS             complement(66990..67715)
                     /locus_tag="VIB18_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765392.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            67787..68206
                     /locus_tag="VIB18_000360"
     CDS             67787..68206
                     /locus_tag="VIB18_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8765393.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            68203..68559
                     /locus_tag="VIB18_000361"
     CDS             68203..68559
                     /locus_tag="VIB18_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ8765394.1"
                     /translation="MKVKTMIAVGLLSFTAYKTYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQGDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(68670..69953)
                     /locus_tag="VIB18_000362"
     CDS             complement(68670..69953)
                     /locus_tag="VIB18_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8765395.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSYSSYANYSSGVDTGSSYQSASTDQDSTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(69962..70486)
                     /locus_tag="VIB18_000363"
     CDS             complement(69962..70486)
                     /locus_tag="VIB18_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8765396.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSRTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            complement(70461..70922)
                     /gene="tsaE"
                     /locus_tag="VIB18_000364"
     CDS             complement(70461..70922)
                     /gene="tsaE"
                     /locus_tag="VIB18_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEQ8765397.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            complement(71076..72536)
                     /locus_tag="VIB18_000365"
     CDS             complement(71076..72536)
                     /locus_tag="VIB18_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEQ8765398.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFNSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            72801..73613
                     /locus_tag="VIB18_000366"
     CDS             72801..73613
                     /locus_tag="VIB18_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8765399.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALGYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            73965..74957
                     /gene="manX"
                     /locus_tag="VIB18_000367"
     CDS             73965..74957
                     /gene="manX"
                     /locus_tag="VIB18_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEQ8765400.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            75046..75855
                     /locus_tag="VIB18_000368"
     CDS             75046..75855
                     /locus_tag="VIB18_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEQ8765401.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGIIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            75872..76783
                     /locus_tag="VIB18_000369"
     CDS             75872..76783
                     /locus_tag="VIB18_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8765402.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            76897..77256
                     /locus_tag="VIB18_000370"
     CDS             76897..77256
                     /locus_tag="VIB18_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEQ8765403.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            77649..78926
                     /gene="serS"
                     /locus_tag="VIB18_000371"
     CDS             77649..78926
                     /gene="serS"
                     /locus_tag="VIB18_000371"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEQ8765404.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQ
                     SEELKAERNIASAAIAQAKRQKEDASQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVSVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADSKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(79159..79929)
                     /locus_tag="VIB18_000372"
     CDS             complement(79159..79929)
                     /locus_tag="VIB18_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEQ8765405.1"
                     /translation="MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGRNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(79926..80792)
                     /locus_tag="VIB18_000373"
     CDS             complement(79926..80792)
                     /locus_tag="VIB18_000373"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEQ8765406.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            complement(80801..82165)
                     /locus_tag="VIB18_000374"
     CDS             complement(80801..82165)
                     /locus_tag="VIB18_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEQ8765407.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAH
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            complement(82197..82619)
                     /gene="fabZ"
                     /locus_tag="VIB18_000375"
     CDS             complement(82197..82619)
                     /gene="fabZ"
                     /locus_tag="VIB18_000375"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEQ8765408.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            complement(82616..83116)
                     /locus_tag="VIB18_000376"
     CDS             complement(82616..83116)
                     /locus_tag="VIB18_000376"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEQ8765409.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            complement(83118..84350)
                     /gene="fabF"
                     /locus_tag="VIB18_000377"
     CDS             complement(83118..84350)
                     /gene="fabF"
                     /locus_tag="VIB18_000377"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEQ8765410.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            complement(84365..85099)
                     /gene="fabG"
                     /locus_tag="VIB18_000378"
     CDS             complement(84365..85099)
                     /gene="fabG"
                     /locus_tag="VIB18_000378"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEQ8765411.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPIKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            complement(85089..86027)
                     /gene="fabD"
                     /locus_tag="VIB18_000379"
     CDS             complement(85089..86027)
                     /gene="fabD"
                     /locus_tag="VIB18_000379"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEQ8765412.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVTPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCNSVENMVSLRLFLDREDIHGN"
     gene            complement(86052..87023)
                     /gene="fabK"
                     /locus_tag="VIB18_000380"
     CDS             complement(86052..87023)
                     /gene="fabK"
                     /locus_tag="VIB18_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEQ8765413.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            complement(87224..87448)
                     /locus_tag="VIB18_000381"
     CDS             complement(87224..87448)
                     /locus_tag="VIB18_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8765414.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            complement(87509..88483)
                     /locus_tag="VIB18_000382"
     CDS             complement(87509..88483)
                     /locus_tag="VIB18_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEQ8765415.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            complement(88484..88918)
                     /locus_tag="VIB18_000383"
     CDS             complement(88484..88918)
                     /locus_tag="VIB18_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8765416.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            complement(88995..89771)
                     /locus_tag="VIB18_000384"
     CDS             complement(88995..89771)
                     /locus_tag="VIB18_000384"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEQ8765417.1"
                     /translation="MIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVKRDTSV
                     RFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKPVILCA
                     DGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNRATHLV
                     MTGEGITADKGIDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVWQSFFT
                     GWEDYAKAELAIQEELAFKEDFKEGVRAYGERRRPNFQGK"
BASE COUNT        27097 a        19473 c        15964 g        27246 t
ORIGIN      
        1 aaaaatagtt caaaaagcaa gtatttaaat accaataccc ctaaaaatac aatgctagct
       61 ttgtgacata tcatttagcc gatcaaaggt tagcaatagc aactgataat gcggcatatc
      121 ttttgctttc ttgagaaaat attttaagtt ggtctcgttt tctgtgtcat aaaaaacata
      181 agccccttct gtcttttcta ataaaaactg ataatattga ctaaattgcg tcggttgttc
      241 gtaatttgga aagtaatatt ttacaaagtc aacagcccta aactgactta aaacttcttg
      301 atttttttca ttccacctat ctccatgcgt ttcaaacaag aatatagtag ctatctgcaa
      361 gagatactcc tcttttagct cattagctac ttccaaagcc cattgttcaa aacccaagtt
      421 ccctgtaaag ataaaccaat ccacaccatt ttccaaataa cctattaaat ctttacgaat
      481 agcctgttta ataattgaaa ctcgtgggtc tttatggtca aaaatcccta tttcaaagct
      541 tcggtaacct gtaattagaa tcgcagtcat taggtgttat cctttcaaaa aatatgttat
      601 aataaaagtg cttaaatttt tagcattaac tagataatat taggagaaca atggttaatt
      661 atcctcataa tcttattcga caaaaagtaa gttccgttca aaagcaaaca aagcaaaata
      721 aggtggactt cgccaataga ggtatgtcct ttgaagctgc tatcaacgcg acaaatgatt
      781 attatttatc tcgtcaaata gctgtcattc acaaaaaacc tactcctgtc caaattgtca
      841 aagtggatta ccctaaacgc agccgggcaa aaatcgttga agcgtacttt agacaagctt
      901 caacgactga ctattgcggc gtttataaag gacattatgt tgattttgaa gcaaaagaaa
      961 ccaggcaaaa aacagctatg cccatgaaaa atttccattt acatcagatt gaacatatgg
     1021 cttgcgtttt acatcaaaaa ggaatctgct ttgtccttct tcacttttcc acactgaagg
     1081 agacttacta cctacctgct caagccttga tttcatttta tcagatagat aatggcagta
     1141 aatcgatgcc cattgattat atcagaaaaa atggctttaa ggtagcattt ggagcctttc
     1201 cacaagtccc ttatttaaac ataattgaac aaaatttttt aggcggtgat tacaattaaa
     1261 aatccaaaaa tccttaagtg gctaaagtat gtattaagtg caattcttag ccttattatc
     1321 cttgttatta ttattggtgg tcttttgttt accttctaca ttagcagtgc tccgaaactg
     1381 tcagaagccc agttaaaatc aacaaactct agcttggttt atgacggtaa taacaatctg
     1441 attgctgatt tgggttctga aaagcgtgaa aatgtaacag ctgatagtat ccctattaat
     1501 ctagttaatg ctattacctc aattgaagat aaacgtttct ttaaccatcg tggagtagat
     1561 ctttatcgta tttttggtgc tgcctttcat aatctaacga gtcagaccac tcaagggggg
     1621 tcaacgcttg atcagcaact cattaaacta gcctattttt ctactaatga atctgatcaa
     1681 accttaaaac gtaaggctca agaagtttgg cttgctcttc aaatggagcg aaaatatact
     1741 aaacaagaaa tcctgacttt ttacatcaac aaagtatata tgggtaatgg caactatggt
     1801 atgctgacag ccgctaagtc ttattatggc aaggatctta aggatttatc ttatgcccaa
     1861 ctagccctat tggctggaat ccctcaagct cctagtcaat atgatcctta ccttcatcct
     1921 gaagctgctc aaaatcgccg taacgtcgtg ttgcaacaga tgtacatgga aaaacatctg
     1981 acgaaagcag aatatgaaac tgccatcgca actcccgtcg ctgaaggtct acaatcactc
     2041 caacagcgct caacttatcc aaaatatatg gataattatc taaaacaagt tattgaagaa
     2101 gtcaaaaaag aaacgaataa agatattttt accgctggtt taaaagttta taccaatatt
     2161 atccccgatg cgcagcagac tctttataat atttatcatt ctggtgatta tgtttactat
     2221 ccagaccaag atttccaagt tgcttcaacg attattgatg tgacaaatgg tcatgttatt
     2281 gctcagcttg gcggacgtaa tcaagatgaa aatgtttcat ttgggattaa ccaagctgtt
     2341 ttaactgatc gtgactgggg ttctaccatg aagccaatca cagcctatgc tcctgctatt
     2401 gaatctggtg tttatacttc tactgctcag tcgactaatg actcagtcta ttattggcct
     2461 ggaaccacta cccaattgtt taactgggac cttagatata acggatggat gacaatccaa
     2521 gctgctatta tgctatcgcg aaatgtccca gcagtccgag cactggaagc cgcaggactt
     2581 gactatgctc gatctttctt aagcagttta ggtattaact atcccgaaat gcactactca
     2641 aacgctatct caagtaataa cagtagctca gataaaaaat atggtgcaag tagtgaaaaa
     2701 atggccgctg catacgctgc ttttgcaaat ggtggtattt atcataaacc aaggtatgtc
     2761 aataaagtgg aatttagtga tggtacaagt aaaacttttg atgaaaaagg aaaacgtgcc
     2821 atgaaagaaa ccacggccta tatgatgaca gatatgttaa aaactgttct cacttatggt
     2881 acaggtactg ctgctgccat tcctggtgtt gcgcaagctg gtaaaacagg gacttctaac
     2941 tacactgatg aggaactagc taaaattggt gaaaaatacg gcctttatcc agattatgtt
     3001 ggtacattag cgccagacga aaactttgtt ggctttacta agcgctacgc catggctgtt
     3061 tggacaggtt acaaaaaccg cttgacccca gtatacggat caagtctaga gattgcatct
     3121 gacgtttatc gtagcatgat gacttactta acaaatggtt acagtgaaga ttggacgatg
     3181 ccaaatggtc tttatcgcag tggtggattc ctctacttaa gcggaaccta tgcgagcaac
     3241 accgactata ctaattcggt ttacaacaat ctttacagca ataacacgac aacagcttct
     3301 agtcaaacga cttcagatga tactagtagt agcaatgata caagtaattc aaccaataca
     3361 gacaacaatg gcagtcatcc atctaccgat gataaaaaga caactcatta atctctaacc
     3421 tctacttatt gtctgtacct accttttatt acatatccat ttagttactt ttaatatcta
     3481 ccttaagtga taatctaaat aaaaagcgag tccacgttct gtgaggactc gctttttata
     3541 tgacacaaat gacttaccac atacaatata aaacaaaaaa cagaattctt taatcgtatt
     3601 aaagaaaagg tacaacgtta agggaattag caactgattt ttcaaacgtt aacctaaaac
     3661 aaaatagact tatttaaaat tgttataaat agcaactaat gccataagag agtatacatg
     3721 aaaaaaacac gtttccatat accgaagacg tgttttttca tatgtcattt tcttagcata
     3781 ataatttttt tcatgttcac tttcttatgc ggagtccaat ccgtttgctg ttcgttttgt
     3841 ccagctttta gatttcatac agtcgcaaag aaaggaatta gtattgtgct aaagcaccca
     3901 ttggatccca aggagctagt acttgtggct ctttttcata agccgctaac tcgtcagctg
     3961 ttaagaattc tttacggaca acaatttgat aggtatattc atccatccaa gcatctgaag
     4021 caacaaagta acctttgtca ccaaccttct caccccatga attttcaacc ttccatttta
     4081 acggttttcc tgtttcatct aagtcaacac ctgttaaaac catagcatgt gtcatcaaac
     4141 tttcactata atccaaacgt ccagccttat cttgactaag attgatatcc atactagctt
     4201 caaaatcgta agtattagtt gccaaaatgc ctttttgacg atctgaaact tgacccacat
     4261 cagagccaaa ccaaacggac tcaccagcct gcatctgctt gatagctagt tctttgaaac
     4321 gtttcatatc aaggttgagg tagcgaacct cacgactacc gaccacattt cctagcatct
     4381 caacagtgta tgatttgcca taaggcttat cggcagttgg cgcattaata acagacacat
     4441 aatcagaaag ctttaagcca acaaatttgt cgtaaaacgc ttgcggtgtc aaacctttct
     4501 caacatgata gtggtcatct ttatcacggt aggcaaaatc aaaatgacga ggtggtaaac
     4561 caagggtcat ggccaagaag ttaaaaattt cctgaagaag ctctgctttt cgatcctcaa
     4621 cttggtctgc cttagcacct gacgcaatca ggtcacgaag aatttgagca tcttggcgca
     4681 ataatttatt caaatactgg tttaattcac gactgttact tgatgagatt gattctgggt
     4741 aaacagattt tggcaccact ccatacttct caaacaagga aaccaccatg tcccactgac
     4801 caccatcttg ttgtggaaca tccaagagaa acttaacttt acgactggtt aattcttggt
     4861 cagctgtagc aatgacctgc tccataaacc agttagcttt ttcatactta tcccaaaaga
     4921 aagtatgagc ttgtgacagt tcaaaatttt ctaacttaaa ttctgtgatt aatttgtgtc
     4981 ggaaagtgtt caaggcagca aacatccagc aacgaccaga agccttttgg ttagatacct
     5041 tatctttagt taaatcaata gaaaacacaa aatcattgtc cacttcactt tgacgggttt
     5101 ctaatgattt tagcaaacca ttatgcgtaa cggcattctc aatagctgaa aattttgcat
     5161 tggcttcgta atgagcaaat aattgttctg taaatgtctc tgttaatgct gacattattg
     5221 tcctcctaaa atattaagat aagcttcacc tgaaataata ttggcaagat ggttattatc
     5281 cagccattct attctaaagg attacttcta ttatagacct tatttgattt tcttcaagaa
     5341 aaaagttagg ataacctaac tttttttgtt ttcttttttt actctttgaa catcatctct
     5401 tatttccaaa aatcatcaaa aatggtgatt ggcaggtgac gcttgtgttg tcctttatgc
     5461 caccattttt caatagttgc ttgagctact ttggaaatca gcttcccttc caaatagtcg
     5521 tcgatgtctt gataggtcac ccctagagca acctcatcag ccaagcctgg tttttgatct
     5581 tctaaatcag cagttggaac tttttcatac aaagcagcat ctgctcctaa aactttcaaa
     5641 agagcctttc cttgacgttt gttaagccta aagaggggaa gaatatctgc tccaccatca
     5701 ccaaatttag taaagaaacc agtgatgttt tctgccgcat gatccgttcc aataacagca
     5761 ccagccattt ggccagcaat ggcatattga ctgatcatcc gctgacgtgc tttgatatta
     5821 cctttattga aatcagaaat ctcgatgcca gcttcttgca aggctgctac ttgaccgtcc
     5881 acagctgcct tgatattaat ggtaagggtc tgatctggtg caataaaagc caaggctttt
     5941 tgcgcatctg cttcatcagc ctgaacccca taaggcaagc gaacagctat aaattggtaa
     6001 gcttgatcac ctgtttcctc ccgtaactct gcaatggcca tctgggctag ctttcctgcg
     6061 agggtagaat cctgacctcc agaaatgcct aagacataag tttttaaaaa tgagtgctta
     6121 cgcagataag cttttaaaaa atcaacagtt tttcgaattt cttcttgtgg gtcaatgcta
     6181 gccttgacgc ctaattgtcg gataatctct tcttgtaagg tcattttaaa tcactctttc
     6241 catgagtatc tttacgaatg ttatcaatta aggtcatctt attttgccac acatctcgtg
     6301 ccaagtctac tgggtagtct tgaggattta agacacgctt gtattcatcc caaagcttgt
     6361 caaattcttt tttagcataa gccttgattt cagctaaggt cggtagctgg taaactaatt
     6421 ctcccttgac aaaaatatca actaagagag gaattgcatc aaaatttctg acggttttct
     6481 taatataggt ataggtcgga tggaacatct caatctcagt taattcatta acattaatat
     6541 cagtaaacgt gatatagtcg ccttctgatt tgcctttttc acgactggtg atgcgccaaa
     6601 cttgtttttt acctggtgtg gatacttttt ctgcattatt tgataatttg atcgtatcac
     6661 gcatgctacc atcttcttgc tcaatagaga caatcttata aacagcacct aaggcaggct
     6721 gatcataggc tgtgatcagt ttggtcccaa caccccaaac atcaattttg gccttttgca
     6781 tttttaagtt gaggatggta ttttcatcga ggtcattaga agcatagatc ttagcctcgg
     6841 taaaaccagc gtcgtctaac tgctgacgga ctgtttttga gaggtaagcc aagtcaccag
     6901 agtccaatcg aacacctaga aaattaatct tgtcacccat ttctttggct actcggatag
     6961 ctgttggcac acctacttta agtgtatcat aggtgtcaac aagaaataca caatctttat
     7021 gggtcttagc ataagccatg aaagcatcat aatcattacc ataggcttgc actaaagcat
     7081 gagcatgcgt acctgaaaca gggatatcaa agcgtttacc tgctctcaca ttacttgttg
     7141 catctgctcc accaatcatc gctgcgcggg ttccccaaat cgcagcatct agttcctgtg
     7201 cacgacgggt gccaaattcc aaaaggggtt catcctcaat cacagaacga atacgagcag
     7261 cctttgtagc aatcaaggtc tggaagttaa caatgtttaa aagagctgtt tcgaccaact
     7321 gacactgacc tagagggcct tctacttgca caatcggctc attagcaaaa accaaatctc
     7381 cttctttagc tgaacggatg gtcaattcta atcgtaactc tttaaggtag gtcaaaaagt
     7441 tttctggata acccagttct tcaaggtaag ccaaatctgt ttctgaaaat tgaaattgct
     7501 ctaggtactc caccatgcgc tgtaaaccgg caaaaacagc ataaccattg ttaaaaggtt
     7561 ccttgcggaa atagacttca aacaccgcat gacgattatg aatgccctgc tcaaaataaa
     7621 cttgcatcat attaatctga tacaaatcag tatggagagt taaactatca tctttataca
     7681 taaaggggac tcctttgaat tattgttact attataacat attttaaaaa ggactctttg
     7741 gctagggttt agaaataact tgagttatcg ctaaagtaaa aaaagaactg atccatcatg
     7801 acatcctcaa ataagaaaga gttaatggat tcagttctat atcgctaatt attatttaaa
     7861 tttgacattg ctataaatcc caaaaacaat aatccaaatc gttgctccaa tggcgccgat
     7921 ataggtggat tcttgtaaga aaagagagat aaagacaaaa gcaaagaaag caagggtcaa
     7981 aggcgttgtc actttatatt ttggcatcaa ataaccatct gccataaagt ccttagattg
     8041 acggtacttc cagtgagcaa tcatggttaa ggcgtagata gcaatatata cacctgatga
     8101 ggaggccgta atgagtgaga acgcatctgc aactcctggt aggatattaa tcaaagctga
     8161 gataccaacc acaaccgctg aagcaataat ggcacgactt ggcacccctt gtcgagataa
     8221 agtattaatc tttaagcgat tggtcaaagc gtttggagtc tcattagcaa tctgatagag
     8281 atgacgaccg gttgaataaa gggttgagtt aagcgctgac gctgctgatg tcaagaccac
     8341 aaagttaatc aaggctgctg cccatttaat accaatcaat ttgaacacca tcacaaaagg
     8401 agattcatca actggtaact gatgccatgg cacaattgcc ataatagaga ccaaggctcc
     8461 cacataaaag atcacaatac gggttggaat ttcttgaata gcctttggta gaacttttct
     8521 tgggttagcc gtctcagaag tagtaattcc cacaaattcg atagcttgat aagcaaagaa
     8581 aaccatttgg aaggccataa agaactttag tttcccattt gggaacatgg aaaaatggtc
     8641 aaaaatattg gaaaggctag catggcctgt gtgagtttca aaacctgtca ataccatgaa
     8701 aatagctgtt gcaatcaaag ctaaaatagc taaaatctta atcatggcaa accaaaactc
     8761 tgtttcccca aaaacgcgca cagcaattaa gttgatcgaa ctaagtaaga ctaagaaaac
     8821 caactgaatc aaccaggctg gccagtttgg gaaccaaaat tgcacataag cacctactgc
     8881 tgtgatttct gccattccaa taaaaataag ggaaatccaa taggatagac ccgaaaaata
     8941 accccagcct ggaccaatgt atttggaaat aaaattgata aaggtgtgtt gatctggatc
     9001 ataatagagc atttcaccga tggcacgcat catcataaac atgaaggcac ctgtaatcat
     9061 atacacaaaa ataatagatg gtcctgttag ggcaatagag cgtcctgccc ctaaaaagag
     9121 acctgttcca atcgttcctg caatcgcaat taactgcaca tgacgatttt ctaagcccct
     9181 taccattcca ttttctagtt cgttattgtc tgtttgttct tttatagaca ttctaaactc
     9241 cattcactaa aatactattt attatatcct tttttcagaa aattttcaac atttatctag
     9301 gaaagatatt aaggaaaact gttctttata tttcttaaag gtcttatgca atttagcttt
     9361 tttaagggag agacaaggaa aaatgaagga gttttaacct tatgaagaga aactttcaag
     9421 gtagtgataa acaccttgcc ctgcaattgc accatctcca acagctgtcg tgatttggcg
     9481 aaggtctttt tgacgaacat ctccaatcgc aaaaatacca gggatacttg tcctcatatg
     9541 atcatctgtg ataatccaac cttctgaatc ggtaatttct agattcttta ccatacttgt
     9601 aacaggattc ataccaacat agataaacac acctccaaaa gcgtggtcag tgacttggcc
     9661 tgttttcaca ttttcgatta ggacattgga gaccttaatg tcgttacctt tgatttcttt
     9721 gacaactgaa tcccagataa agtcaacttt gtcattagcg aaggcacggt cctgcaagat
     9781 tttctgagct cttagttgat cacggcgatg aacaacggtt acctttttag caaactgagt
     9841 aagataaata gcttcttcaa ctgctgagtc accaccacca acgaccaaaa gatcctggtc
     9901 acggaaaaac gcaccatcac atactgcaca ataagaaact cctcgactag tatagtattc
     9961 ttcacctgga acacctagta cacggtattt agctcccgtt gcaataataa ccgttttagc
    10021 ttcataacta gcatcttcag tcaacacaca cttatagtca ccaaaatttt ctattttttg
    10081 aacaatacca taaatgtttt caacgttaaa cttctctaaa ggttcgtaca ttttcatagc
    10141 taattctggt ccagatatat gatcatatcc cgggtaattc tctatatcaa aagtgttgtt
    10201 catctgacca ccaggtgccc cttgttcaat aatggcaaca gataaattac ttctagcagc
    10261 gtataaagcg gcagtcattc ctgctggtcc tgaaccaata attaatgtat cgtacatgat
    10321 ttttctcctt taatctactc ttgccaatat tttagcaatg ataatccctt cttgcaatga
    10381 ttaggatttt atgacaacca aaatactcat aaaagcaaac gataaaattg ggatggttaa
    10441 aatagcaacc attagcatct cataaagaaa agcttgtctt tcaatcaatg ttttatctct
    10501 tttggttttt gctcgccata aagtccatat taaacaaatt aacatcatag taaggcttga
    10561 gagaatgaga ccttttacat aaaggctaaa gatttctact aacatatttc cacctagtca
    10621 ttatttcttt cccataagtt tttctaaaaa acataacaag aaaagcccag ggatacctag
    10681 acctttttat tataacaaaa gaataacatt aaatgtatgt ttttgaatag cttgcaaaaa
    10741 attctttggt tcgttctttt tgaggatgtc taaagacttc ttcaggtgtt ccttgttcca
    10801 agattttccc ttgatctaaa aagagtactc tatctgccac ttggtaaaca aaattcatgt
    10861 cgtgactcac taaaaccatg gtctgtccgg atttagcagc atcagtaata gacttttcca
    10921 cttcgccaac taattccggg tcaagagccg aggtcggctc atctagtaat aaaacatctg
    10981 gtttcatagc cagagctctt gctaaagcta cccgttgttt ttgtccccct gataaatgac
    11041 gtgggtaatg atgttttcga tctgctaaac caaccttagc caattctgct tgcgccagtt
    11101 tagtcgcttc ttggtcagac agttttttga ccaccttaag accttctttg acattctcaa
    11161 gggctgtacg acgctcaaaa agattaaatt gttgaaaaac catggcaagt ttccgacgta
    11221 aaataaggac ttgctctgtg gtaatggtct caaaatcaac cgtaaagtca ccaatgctaa
    11281 tggagcctga atctggtttt tccaaatagt ttaggctacg aaggaaggtc gatttccctg
    11341 ctcctgaagc accaactaaa gcaatcactt gacctttttc aatatcaaga gccaaactat
    11401 ctaaaacttt ttgccctgag aatgtcttgc tcaaatttct aattgtaatc atcaacgcaa
    11461 ttctcctaac ttttcatttc tagcttgttc tggtgctttg atggccatct tgttttcaat
    11521 caagcgacct acttgctcca tcaaaatact gatagaccaa tagacaagag caacagagat
    11581 ataacgttca aaataacggt aatctgatcc gcctagaatt tgagcctggg caaacatttc
    11641 gacaatccct gcattaaagg caagcgatgt tcctttagtt aagccaatta acccattaat
    11701 caaggttgga atagccacaa cagttgcatt aggaataatg acacgacggt aaacctgcac
    11761 agaagtcatg cctagacttt ttgctgcttc aatttcacct gtatctactg ataaaatggc
    11821 tgcccgaata gtttcactag cgtaggctgc ttcattaaaa gcaaaggctg taatggcaaa
    11881 aatagaagcc ggaattgcat taacattcca atcaaagcca tacttctgat tgagaaattt
    11941 tagaaagagg ggaataccgt agtaggtcaa catcaactgt accaaaatag gagttcctcg
    12001 caagaaactc acaaaaatag cttgaatagg gtatagtagc ttcactttat taattttgac
    12061 aagggcaaaa atcaaagcca aaaccaagcc aaaggttgct cctgatagtg tcaaaccaag
    12121 cgtaattgga agccgttgga taatatttgg aatggcatca aaaacagcat gccaactaaa
    12181 aagtttccca tgtggaatcg gtgagatgag atgatcataa aaagcccaac cactggttaa
    12241 aaacactgat gtcatgtatt tcccctttgt atgtgtttgt cttaatattc taacactctt
    12301 agacccacat gtaaaatagt aaatccgtat tatagcaata agcaaaagct atgatcactt
    12361 tttgtgttaa caaatggtaa acaatacaag tagcaggtgt aaaaaaagca agattagatg
    12421 ccaattgatc acttgcttgc tctttgttct taaaaatgtt gttttttggc cttacgctca
    12481 gcgcggccct tagcacgatt ttcagcacga cgttctttgc gacgtttttc atcaaccgcc
    12541 cactgaattt ttttcttgta acctggtttg acttttttct ttttcttttt gaccaaacca
    12601 atcatttctg tgtctaattt ttgataggct ttttcacggt tttgacggcg atcacggtca
    12661 taggtatctt gaaattctcc atttttgagc accttcggtg taaaggcaat ccccattttt
    12721 tccagctctt tgatatctga gtcgtcactt ggctggtaaa gtgtaatggc agttcctgcc
    12781 ataccatttc gacctgttcg gcctacacga tggacaaaga aagacaagtc ttgtgggatg
    12841 gcgtcattga tcacatggct gaccccttca atgtcaatcc cacgcgctgc taagtctgtg
    12901 gcaacaatgt attcaaagtc cagttttttg acttggttca tgatgcgctt acgttctctt
    12961 ggaggaatgc ccccatgaat tttagccact tttaagccat tagctgttaa aaaggcatgc
    13021 aaatcatctg cgcgttcctt ggtattgaca aaaagcatag ccatataagg ctgcatagtt
    13081 ttgagaattt ctaacagttg accattctta tcacgccctt ttgtcgacac aagccagtta
    13141 tcaatggtat ctgcgataac ggtctttgtc ttgatttgtt caataacagg attggtcaag
    13201 tattttttca aaaagggttg taatttctgt ggaatagttg ctgagaacac caaaatctga
    13261 acagattttg gaagcgaagc tgcaatctta tctaccgtat ccaaaaagcc catgtccatg
    13321 gtcatatcgg cctcatccac aacaaaggtc gttgctttat gaatcgctaa atcaccagac
    13381 ttgaccaagt cataaatacg acctggggtt ccgatgacaa tatgcggctg gctgcctttt
    13441 agtttttcaa tctgacggag tttgtctgtg cctccaacat agttggccaa acgaatctct
    13501 tcttggaagt gcttagcaat ctgtttacaa gcatcaaaaa tttgagttgc taattcacgg
    13561 ctaggtgctg taataacgac ttgcacttct gctttagctt catcaagttt ttcaaaaatg
    13621 ggcaacaaaa aggtgtgggt tttccctgaa cctgtttttg attccccaac taagtcacga
    13681 ccggagttaa caataggaat cagccgcttc tggacctctg ttggattgac aaagccaatt
    13741 tcttccagcg cttgctgaac gtattgctta aaatgataat ctttaaatga catgttttac
    13801 ctcgttttct tccatattat atcattattg ttagagacaa gcaaaaggag tgggacaaca
    13861 ctcacaaaat cagcatttgt gggtcatctc cactctctta ttgatgatgt taatcaaaat
    13921 gctattggtg actattcttg ataatccccc ttagaacacg tataagatag ctaaaactag
    13981 taaactagct agacttccta ctccccacaa aaaagcatct acctgccatt ctgaccactt
    14041 cttgccttta ccagacaagc ctcccaattc caaatggtgg tggaaaggcg tcattctaaa
    14101 aatacgacga ccttctccat attttttctt ggtgtacttg aaataggaca cttgcaacat
    14161 cacagaactt gtttcaagaa cataaacgat cccaataatc agaagagtcc attcttgacg
    14221 aagcgcaata gaaatggcag ccaacatagc tccaagggct aaactaccta catctcccat
    14281 aaatacttta gcaggtttgt gattaaagca gaagaagcca agcaaggctc caatcattgc
    14341 tccaatcagt aacaaaacat caaattgact ctgaacgtag gcaataacgc cgtaagtcac
    14401 tagactaatc accactgaga tagaagctaa gccatcgata ccatctgtca aattaacggc
    14461 atttgaaaaa ccaaccaccc aaaacaaaac aaagaatagg tagaaaattc ccagcggcag
    14521 ctgataacca aacacattaa tagaggaaat gccacttgga ctaacatgta aaaaatagaa
    14581 catcaatcct ccaaccaact gcaaggctaa cttttgtttg gctgtcaatc cttcattgat
    14641 ttgcttaaaa atttttaaaa aatcatccaa aaatccgata atcccgtaaa tgacaacaat
    14701 tgataaaatg cctgaaatca aagctaaact ttgagtgttt ttgatcgaaa atagactaac
    14761 caataacgat actgccgtag ctactaaaag aaaaacagtt ccccccatag tcggtgttcc
    14821 agctttagct aaatgttgct tgacatcttc atgcatttgt tgtccaccaa tttttttcaa
    14881 ttgatagaat ttgataaaat aaggcattgt gaaagcagat accataaagg atatgattgc
    14941 tgcaataagg gttaaaaaca tgttaatctc ctaaagtaat ggtcattttt tttatttttt
    15001 tcaaggactt accaacatca acactttgtt tcataacacg accagaatct gttcctttaa
    15061 agctgatgtc tattccagtc catttagcaa aggttttaac attggatttt gtccagccat
    15121 acatgtctgg tacctccaca aaacggtctg ataatatgag aacttgttgg ttttctgtta
    15181 acgtttgacc gggctgatgc gatacttttt tgatcttgct gccagtacca aggacaactg
    15241 gctggacaag atttcgacgc aactcgcttg atgtctcacc aggattcttt cctacaaagt
    15301 ttggtaattt ataagttgtt tgacgattag catctgatac tactggctta gttagtgtat
    15361 cttgcattaa gtatgcttct tccaatactg ggttaaccac atcttgccaa aaaaggggac
    15421 caaaatgttg tggtttagtc atagtaacat acatcaaaaa gtctggttta tcagctggca
    15481 ccattgccac aaccgaatag acatagttag tcaatccacc atcttgataa ccacttccat
    15541 cttctgaacc aatttgtgct gttcctgatt taacagcaac aggtaaatca cccactttaa
    15601 taattggtcc aaatgttttt gaatagagtg ttccaaactc agggtctgtt cctacaccaa
    15661 tcatgtattg tcttgtttca ctagcggctt tttttgatac aggttttcca acaatttctt
    15721 tatttgccgt tctaaaactt gctgtgttag gatcataaat ttgactgata aattgtggct
    15781 ctaacatctc accattatta gaaatagcag taaaggctct aagcatttga atctgggtta
    15841 cagaaatccc ttgaccaaaa gcgctcatag cttgagtcac gatattatca gaaggaaata
    15901 tacctgcgtc ttcatctttt aaaccaaaac gagtaggaaa accaaagcgg aacttcgtca
    15961 aataattcat ccattttgca ttacccattt tttgttcaag tttagtcatc ccaacgttac
    16021 ttgagaaggc aaacccttgt gcataattca tgtactgtcc tgtggaaatg ccttcattaa
    16081 tagaccagtc ttgaatagta gcatctgcaa ttgttaaacc attagcattg ctaaaggttt
    16141 cgtttgggtt gaaaacttta tcatcaatag ccgctgccag agtcatcact ttcatggttg
    16201 agcctggctc aaaatttcct tgatgaagtg cactgtacca tttgtagttc gtattttcaa
    16261 gtcctttcag agtatcagca ttataagtgg ggcgttgtgt tgttgccaaa atttcaccag
    16321 ttttagcatt aacaagtgtt gcactggcca actgaccatt tgatttggct tgaaaaacat
    16381 ccatctgggt ttctaagaag gtctggatag gctcagatag cgttgtgtaa atatctttgc
    16441 catcaatagc tttcttgaca gtcttacctg tacccaagag tgtggcccca tttcgatctt
    16501 tttgataagt aataacacca tcttgacctg ataaaatttt atcaaaagaa gcttctagac
    16561 ctgtttttcc aactaaactc ttaacacctg tctttttatc ttctgttaga gatgctaggc
    16621 ctataaattc tgaagcaaat gtcccatttg gatacatacg accaggacta gttgtgaaag
    16681 caattccctt gattttggca tcttccatag ccttttgaat agtagacata gtactatatg
    16741 aaatgccaga ccctgacggt ccaaacgaga cttggaaaag tcctttacgc ttaagctgtt
    16801 taattacatc tgtttttttc attcccagat gcttttttaa aatatcagct actgtttcat
    16861 actgagaagg ttgtacatat aacttttcat ctgaagccga gacaaatgat ttatccaaaa
    16921 ttgcgtatat gctataagtc gtagaatcca ctgcaatagc tgtaccattt cgatcataaa
    16981 tggtcccacg cttagcttgg atcgtaacgg tttcttgata aaccttcttc gccccttctg
    17041 acaaactaac tccaaacttt tgatctgttc caataataat catgaaatta ataatgaaaa
    17101 taaagaaaat aaagatagtt aagagcatca tattttgtcc aactcgaacg cgattttcga
    17161 ctggagttct cctatcgcgc acaacataat ctaaaacata tttttgccat tttttcatag
    17221 attactcgac tttcttgata ttattattac ggttgcttaa gcctgcttta ccagcaatat
    17281 ctataatacg atcacggcga gataactcat ttacttcttg cttggcatta ttaagctcta
    17341 gtttttgatc cgaaatatga ctatttaaac tagtgatttc ttgttgtagc tgcaacttac
    17401 gactttgcag gtaaataata cttactgcca tcgtaatcgc tgttacaatg atagcagtat
    17461 aaaaagcctt ctcaattcta gagaaagttt ttattcgttt ttgcaaggca tttgtaactg
    17521 cctgagttct tttttcattt gtcataggct tatttccgaa tttttttggc aacacgtagc
    17581 ttggctgagt gtgccctttt attagctgtt aactctgaat gactaggtaa gatcggctta
    17641 cgtgaaacaa gttcaaactt aggtttcata tcttcaggaa ttagaggaag cccttttggc
    17701 acatccaccg tactagcttc tttaaacaac tgcttggtta ggcgatcttc cagagaatgg
    17761 aaggtaataa ctgagatacg accatcaagg gctaataatt ccatagcgtc ctgaatagat
    17821 tcatcggccg ctcccaattc atcattgact tcaatgcgaa tagcttgaaa aatctgttta
    17881 gcagggtggc cttttttctt caactcttta gctggctttg ctgtcttaat caattctgcc
    17941 aactctgttg ttgtctcaat aggcttaata gctcttgctt gttcaatttt tcgagcgatc
    18001 tgcttggaga atttatcttc accatatttg aaaaaaatct taaccaaatc attgaatgga
    18061 taggtattca ccacttcgta agctgttaag agcgactgac gatccatgcg catatccaat
    18121 ggagcatctt gtttataaga aaaccctcgt tctctttcat ccaattgcgg gctggaaaca
    18181 ccaaggtcgt ataagatacc atcaatttca tcaactccaa gcgctgttaa acgtgctttg
    18241 aggtgtctaa aattatcttt aataaaagtt acctgtcctt tgtcaatata agatttgagg
    18301 gtaacttgtg cattgtcaat agccttttgg tcttggtcaa aacaatagag gtgcccttct
    18361 tcaccaagtt tggacaacag ataagctgag tgccctgagc cacctagcgt cgcatcaaca
    18421 taaatcccat caggctttat gtcaagcatg tccactgttt cgtgaaggag tacggtcacg
    18481 tgatgaaatt cttttgtcat aactttaatt gtaccatact tcaaaaggtt tagaaatgaa
    18541 aaagtaagag aaaaggattt cattctcgtg ggaatcttcc tcttctctaa tcttgttctt
    18601 tttgttcgct atcagccaac ttagcaagca ctgacttagc cgctgcctct agagtttcaa
    18661 ctgcttgtaa aagattttta gcttccttaa acacgcctat ctgtcagcgg gttgtctaac
    18721 caaatatcaa aggttttatc ccaactcgta tttggtaagt cagctaataa tagcctatcg
    18781 acgtctacca gctatcttcg gcagttttga agagtaactt gtaagtctat taataattgg
    18841 ttgaccttgc tcattatttc gacgtttgat ccagctgaca agcataccat ctccaaaaaa
    18901 aaaaaaaaaa tagccccaat ttcggacaat tttcaattcc aaatgaatca cctgaatctg
    18961 atgtaaaagt tcttctaaag taacctttgc ttcttctttt tctctttcat tagtcattaa
    19021 gggaccttct agtagcttat tctctgatat gtccatcccc attaatataa aatttagtgc
    19081 tggtcaaggc ttctaagccc attggcccac gggcgtgcat tttttgagta gaaatcccaa
    19141 tttcagcacc aagcccaaaa acaaaaccat cggtaaatcg tgttgaagcg ttgacataaa
    19201 cagcagcagc atccactaaa tcttgaaagg tctctgctgc cttaatatcc cttgtgatga
    19261 tagcttcgga atggtgacca gtatactgat ttatccaaga aatagcttct tccaaagagg
    19321 aaacaacctt aacagacatg atataatcta aaaattcggt ctcaaaatcc tctgcttttg
    19381 caggcactgc ctgctcaaat aacggcaaag ccttgtcatc tgcccgccat tctactggct
    19441 gaacttgatt gatcgctttt tcaagcatag gaataaacct tgctgctaca gcttcgtgaa
    19501 ttaccaatcc ctcagctgca ttgcaaacac ttgggcgctt tgttttagcg ttgataacaa
    19561 tcttagtagc catatctaag tcagcttgag catccacata gatatgcaca ttccccacac
    19621 ctgtttcgat gacaggcact tttgcttttt ccttaacggt ctgaattaat ttagcaccac
    19681 cacgtggaat caaaacatct acataatccg ttgcctgcat caattcttca gcgacagcat
    19741 gtgagggatc ctcaactagc tggacagcat ctggggtgat ccctgatttt tccagacttt
    19801 gtcggatcaa cttcaccaaa gctttatttg agtgaagggc atcttttcct ccccttagga
    19861 tgatcgcatt attggttttg aacgccagac taaaagcatc cactgaaaca ttcggacgac
    19921 tctcaaaaat catcgcaatc acccctagag gaactctctt ttggaggatt ttaaggccat
    19981 cgaggttagt atagccctta atgacttgtc cgattggatc agctaagtca gcaacctgtt
    20041 gaactccctg tgctatcgct ttaatccgtt ctgaagttaa gcgcaagcga tccatcatga
    20101 tgtcagaaat accatgttct ttagcattcg ctaaatcttt ttggttagcg gctaagaaag
    20161 tctgtgtatc gtcaactaat gcctttgcta aggtgcttaa aaagcgattt ttaatttgcg
    20221 tcgacaaagg tgctattaaa agactagctt gttttgccct ttggcctaac cttctcatat
    20281 cagtcatgtg ttacctcttc tatctgcttg aaccaggtgc ctagtggttg cccttcaagc
    20341 actcttaaaa tatctctggg attagctcca ttcatcaaga ccatctgtcc tttgttttca
    20401 aataccatct gagcagactg aattttgcta agcatcccac ctgtgccaaa cttactgccc
    20461 gcaccacctg ctgacgcaat gatttcttgc gtaatgactg caacatggct gcgtagctgc
    20521 gcatcctcat aaatagtagg gtttttatca aaaaggccat caatatcaga caacatgatt
    20581 aataaatcag cttttgtaat accagcaaca acagcagata aacggtcatt atctccaaat
    20641 ttagtcgcat gatccatttc atccacacta accgcatcgt tttcattaac aatcggcaca
    20701 atgcccaaac taatcagact ttcaaaagca ttggtaacat tggctagact ttctgggaaa
    20761 accaccacat ctctcgtcaa taaaatttgt gacacgttgg tttggtagtg tgcaaaaatt
    20821 tgtgaataaa gactcatcat ggctacctga ccaacactgg aaactgcctg ttgtttagca
    20881 agattggtcg gacgtttttc cattttcaaa atatctagtc caaatcccat cgctcccgat
    20941 gatactaaaa taacttcctt gcccttattc atcaaacttg aaatcacaaa agccagttgg
    21001 tcgatttttt ctaaattgat tttacctgtt ggtagcacta atgaactagt gccaatttta
    21061 attacgatac gtgttacatc ttcaaattgt cgtttcatca tacccaaatt atagcataaa
    21121 aaacagcccc agaggactgt ttttccgaat aatgatccct cttcgttaaa gcctctctaa
    21181 gcttttccag aaggtttttt gaatccataa gtgagcaatc cctaaaacca ttagtattag
    21241 acaactcaat agaatactaa tcaacagagg ttgttggata atattggcaa tgataacagc
    21301 tccaaaacct agcacacctg caactattaa attaccaaag ataagtccca ttgttaacca
    21361 ttgcccatct cctctggtaa agagttgtgt catgtcttgc cattttaaat ccagaagccg
    21421 gtagtcacga cgatacataa actccccttg cacaatcaga gacagggcgt agccaagaca
    21481 aaaagcaatc gttagaagag gatgcaggtg caacacaaag agaccaaaca caagataaat
    21541 caccataggc acaatcagtt gcagacctac aagcaagcaa aatttatcca gcaagaattt
    21601 ttttaacgtt attggtaagc ttttaataaa ggtaaagtta tccttttcaa gtgaaatacc
    21661 tactccaata aagctggttg gtgttgcaca catgacaccc aaactaaccc caaataataa
    21721 ggctacccca aagtaatctg gggaaatatg cttaaagaaa cctgtgccac gtgacaaact
    21781 tggaccgata aaaagcatca catacatcag gggcatgaga taggtttgtg tcagtaaagt
    21841 tgcattttgt aacgttaata ggtgatgttt tcgcaacaac tgcgccagtg attgattctg
    21901 atgaggacga ttaactggtt ttttagtttg cttggctttg ttctcgttac taatataaaa
    21961 agcctcacga taataagttg gcatcacttt tgtgacaata ccatatacca tagctaggat
    22021 aagtaacaat ggcaaccaaa agttaaggag ggccgcagta gaaaacggtg tctgaacaac
    22081 atcatagaat cctttgaaat agggaatagt tgggtaatca gtaaatacgc catccgtcat
    22141 cgtacgcttg ttgttactaa tattaatcgc aaaaattaag acgaaagcgc caaaagttga
    22201 gacaaacatc atgatagttg aaatgagttt tcgtttgcga cttcttacaa tgattttgcc
    22261 tacccaagca ttgatataaa tagctaatac catagaactc actagtaaca ctaaaaagag
    22321 cacgatagct actaaaatag acaaaggatt tcccaagagt tgccaatagg caattaagag
    22381 aagagagata agaggcatca aaaagacagc acccatccct agcgacgaga caatttttgc
    22441 aatatagagt tcttctgacg ttactggtaa gtgaatataa agttttaggt cattactttc
    22501 ataaaaaatg gtgtaaagag agctaaaggc tgtcaaggtt gacatgataa aaaacatagc
    22561 aacgtcaaag gagaaaagtc ctggataatg actgaaatcg acaccaataa acataaaaag
    22621 gtaaatcacc aaaaacatgg caatcattaa ggcctgttgc ctcatcatgc ttttataggc
    22681 tttgaagttt tctttcgggt gtttttcctg acgctttttg aggttagcta aactttgtgg
    22741 attggaataa agaatgttta tcttgataag ttcccaaata gtagaccaat tcatcccatc
    22801 acccctcttc ttgcgcctta cgcccagcga gttcaaggta gatgctctcc aagtctttgt
    22861 gaggatggtg ttctttcaac tcatcaatcg ttccaacaaa aatcaatttc ccttttttta
    22921 gaatcccgat acgatcacat aactgctcag cgactgatag cacgtgagtc gaaaataaga
    22981 ctgtatgtcc agaagctgca tgagctttca tcatttcttt aaggtcaaaa gaagcctgag
    23041 gatccaaacc tgttaatggt tcatccaaaa tccagatgtt aggatttgat acaagagcac
    23101 caatcacaat cactttttgg cgcatcccat gtgagaaact atcaatggtt tgattaactt
    23161 cttccttcag ttcaaaaagt gttgtcagct gtgctaaccg ttcttctctg tcctcatctg
    23221 acaccccata aattttagct aaaaactgcc aatactcatt tggagttaga ttcaagaaaa
    23281 tatcaggaga atctggcaca taagcaattt gttttttgat agcttctcta ttttctgtca
    23341 gaagttgacc atccacaaat acttcgccat aactcgcttc gataatagaa gtcaaaatgc
    23401 tgatggtcgt ggttttacct gcaccattat gtccgataag gccaaaaatt tcaccgtcat
    23461 tgatagtgac gtttaaatcg ctgagagctt ctttgtcgcc atacaacttt gaaacatgtt
    23521 taaattctat catggtatcc tttttccttt tcttctcttt ttctccctag actgatgagg
    23581 cttcctctaa aatatacttt tccaatgact gcttaaaacg gcaaagcgat tttggaagta
    23641 aaatgtcatt atcaagtaag taattatcca catcttggtt tagttggtag gcaacaagaa
    23701 gtgggttact gtgtttaatt aatctattag aagctgctaa aagtagctgc gacaaggcca
    23761 cattttcacg attttctgga taatcataag cctgtctaat cacatcgtat aagcgctgtc
    23821 gtttcttttc catttatact cctttatttt ttgtactttt acgctaatac aataacaatt
    23881 aaattataat ttttatgaat cgttttgtca atgacttctt atcaaaagaa gtgtattagg
    23941 cagtttgagg aaaagaaaga actgggtatt ttattttaaa aaaacagagt aaatcaaatg
    24001 atttactctg tttgggatgt ttaacttaga gtgatttgta taactcagtt gcatttgcca
    24061 cagtgaaacc atattcttcg aagatacgat ttcctggagc tgaagcaccc caagtgtcaa
    24121 tggtcaatgt ttttcctgat aggccgacat attttgccca gccaaagctt gaacctgctt
    24181 cgatagcgag acgtttagtc acagctgctg gtaggatgct ttctttatac tctgctgact
    24241 gttcgtcaaa gatattttgt gatggcatag atacgacacg cacatgaatg ccttctgctt
    24301 caagagcttc ttgagtatcc attgccagtt tcacttctga acctgttgca atcaagatac
    24361 catcaaggtc gcctttggct tctgataaaa tgtaagctcc tttgttaaga ccatcttctg
    24421 ccaattcttt tgtgccctca agcactggaa ggttttgacg cgtcaataca agcatggttg
    24481 ggcgatctgt ttcagcaatg gcacgtttcc aagcagcatt tgtttcgtta ccgtctgctg
    24541 gacgaataac gttcaagtta ggcattgagc gaacacttgc caattgttca attggttcgt
    24601 gcgttggccc atcttcaccg acagcgatag aatcatgtgt catgacataa actgttggca
    24661 agttttggag cgctgccata cgaacagctg gaagaagata gtttgagaag acaaagaagg
    24721 tcccgccgta aacgcgtgtc ccgccgtgaa gggcaatacc gttcatggct gcagccatgg
    24781 caaattcacg aacgccaaac cagatgttac ggccttcgta gtgacctggt tggaaatctg
    24841 tttcagcctt aaccatagta ttgtttgaag ctgaaaggtc tgctgaccca ccccagaaag
    24901 aggctacttg ttctgaaatt tgttggatgg cttgttgact ggatacacga ctcgccattg
    24961 aactaccaag ttcgtgcgct tcaagttcta cttgagcagc ttcgttagta aaggcttttt
    25021 ggtattctgc tgctaattct ggatattctg cttcataagc tgcaaacaag tcattccagg
    25081 cttgttctgc tttttcacca cgcgcttgaa gaccttgagc aaagcgctct gttacttcag
    25141 caggcacttc aaaatcttga tgagtccatt ggtaagcttt tttggcaaaa gcaatgcctt
    25201 ctgctccaag aggagcgccg tgaacagctg aagttccttg tttttcggca ccaaaaccaa
    25261 taatggtttt gacttcgatg atggttggtt tctcagtttc agctttagct gcttcaatag
    25321 cagctgcaat ttcttctaaa tcatttccat ctttcacaag gatatgttgc caaccgtaag
    25381 cttcgaaacg tcctttcaca tcttctgtga aagccataga ggttggacca tcaagagaga
    25441 tgtcgtttga atcatatagc aagaccaatt tcccaagttt taaatgtcct gccatacttg
    25501 ctgcttcttg gctgacccct tccataaggt caccgtcacc attcaaagca aatgtgtagt
    25561 gatcaacgat gtcaaagcct ggtttgttaa atttagctgc tagatgagct tctgccatgg
    25621 ccataccaac ggcatttgcg atcccttgac caagaggtcc tgtggttgct tcgacaccgt
    25681 ctgtgtgatt cacttctggg tgacctggtg ttttagaacc ccattgacgg aagttcttta
    25741 aatcttctac agataaatca taaccagcta agtgtaacaa gctataaagc atggcacttc
    25801 catgacctgc tgataggata aaacggtctc tgtttgacca attacggctt gttttgggat
    25861 taatgttcat gaagtgattc caaagaacat aggccatagg tgctgccccc attggaagtc
    25921 ctgggtgtcc agaatttgcc gcttgaatgg catccattga tagggtgcgg acagtgttta
    25981 ctgccaactg gtcaattgca tcaaatgtca taagtaaaac ctctctgttt attacaacta
    26041 aaattaaacg ttttctattg tctattgtat cacaaaaata gacgtttttt tcagaaaatc
    26101 ctccaaagtc cctaaattct ttttctctat tttgccagaa aaaaactagt ttggacatca
    26161 ttggtggatt ctttttgacg atgaatataa gagagcctgt tgacacagtg gccacagact
    26221 ctttagcctt attttttaaa ggaagcccaa tcttccataa aggttttcaa accatttgtc
    26281 gttaagggat gttgcgtcat cttagcaaac aaggggtctg gaatcgtcgc aatgtgtgcg
    26341 cctaatttag caacagcttc cacatgggct gttgtacgaa tacttgctgc gatgatttct
    26401 gcttggaaat cgtacaagtc aatgatttca cgaaggtcgc tgattaattg ataagcatct
    26461 gtgccaatat cttccaaacg accgataaat gggctaatgt aagttgcgcc tgctttcatt
    26521 gccattaaac cttggcttac tgtgaaaatc aaggtcacat tagttttaat cccttctttt
    26581 gaaagaatgt ttgttgcttt taacccttct gtggtcattg gaattttaac gacgacattg
    26641 tcatgccact tagcaatgct tctagcttct tctaccatag catctgctgt taatcctgtc
    26701 acttcagcac tgattggacc atcgacgatg tcacagattt ctttgataac tgtttcaaaa
    26761 tcacgtcctt cacgtgagat aatggttgga ttggtggtga caccatctac aacgccaagt
    26821 tcattaatcg ctttaatagc ggctacatta gctgtatcta ggaaaaattt catttcttac
    26881 ctccaaaaat tttcgatttt gttaagctct atttgataag ctttttcaaa tcatctacct
    26941 ttagactatc ctactttatt attataaaag tgtaacagtc tttagaaaag accaagtatc
    27001 acacagtttt gtgtgcaaaa ctagacttag ctgctgggct gagtgagagt tcctcttctc
    27061 gtgtattttt ttgctggaaa aggtctttga gaaaagcttc taaagcagtg agttcatagg
    27121 gggagctata ctgttttaac cggtaatagg gtaaatcttg tctcggtaaa cagacagtct
    27181 gataggtaat cagacagtca taaactttct gatgatcata gggcattaat tgaaaatccc
    27241 tacgatgccc caaatgacgt ctaatggcca attccgcaat ggctgcttcc accttatttt
    27301 gccccaaggc aagccctact aaaagaggct catggtgacg ctcaatggaa aaaatcaaca
    27361 atgctaaaat gtcgtcactc aactgctgac tgaaatccgt ttcctgaccc atttgcagca
    27421 ctaaatggtt tatgataacc cttaaaagcg ctcttttatc ttcgcctact aattgataaa
    27481 ggtattggct attggttggt tgactaagga tagctccttt aaaaaagtaa gctttggaaa
    27541 aaaatatccc caagccataa atgatttcct cctttgtctg atggataatc acatgagcct
    27601 tctttaaaag ccataaggct tctgaaatgt gatcagcaat aggacctcca aaacccaaac
    27661 tatacttcat gctggcaata ggaagtagag gataagcatg caaaaagaca aagaggctct
    27721 tagcttcaaa agcatcaaat tcaagggcat agcgtcttaa gtaatgtaaa agcatgcttt
    27781 ctaagcgctt aaagaaaata ttagatgtca taaagtcact atctcttaaa aaatgatcat
    27841 tgtagccttt ttgaaaggac attcgcgctt gcgaaatcgc caaccaaatc aataattgtt
    27901 ctaaggcttc tgccgataat gactggccaa tcagccgctc aattaaggta gccaaatgcg
    27961 aagcgtctaa ctgattgacc aaggcgtcta tgccttgtct ggtcaaggta tggcggaaca
    28021 attcaaaata gaaataacgc cactgaagct cacttcccag ttgtctgcct tgcgagagcg
    28081 ccagatcaaa ttctgataaa agctggttga ggtgagctaa ttgtctgttt agagtagctt
    28141 cactaaccat cagttcaacg gataagttgg tgatgttaaa gtgttcatgg cagtacatgt
    28201 aggtcaatat ctgataggca accgattctt tgagaagcag agctaccaaa tcctcccaat
    28261 ggaactggcc attttctttt aagctcagac tgtctttttc taaaagtaat tgacaggcta
    28321 aaccttgttc tcgacacaaa tgatttaggt tgtcaatgta ttttaatagg gtcactttag
    28381 acaagtttga tagcctcatt aggtctttta gccttaacgt ttctttagca tgataaaggg
    28441 tcaccaagag acgatattgg gcccttcgtt ccttatccat taagtcttca atcttcatgg
    28501 cggagcctct tttcaaataa tttgagacaa gcttcatgaa gatgataagc caaatcactg
    28561 tgaccttgta aaaagagaaa atcttgaaat gctaagtcag cgtctgtaac tttcagagcc
    28621 agagcctgac ctaattgatt ggcgatgaca agagcattgg ttttggatag gagctgagcg
    28681 cctattaaaa tcccatccgt ttttctagct attaatttca gccaaaagag gtttttagaa
    28741 tccccatttt ggtacaaata gctacacgta tccatataaa gctctgcttc ttcttctgtc
    28801 acaccaacac tcgcgcgata ataaccaaag tgagaacttc ctaatacctt gaccgtctgt
    28861 aatggaggaa taggatatcc agctaaatgc agagccagag cctgacctgt cttcattgct
    28921 tggttaatca aaggtgtata gtaatccatt cccaatatac caaaatgcaa tgaaaccatg
    28981 tctccaatgg catagatatt agcctggctg gtctgtaagt tttcattaac caaaatggtc
    29041 ttatccagag cacaagccac ttgtccttgc aaaaggtgtg tatttggcct aaagttaatg
    29101 gctaaaatag ccaaatcacc ttggaaggtg tccccttgct cggtatgagc gacaactttt
    29161 ccctctatct catgaatagc cgtaacacgc ttattattaa taaaggtgac atggtgagtg
    29221 gacatttctg ccattacagg ggctatcagt tctgcgtcag tctgatagaa atctggacgt
    29281 tcggctgctt caatcagttt gacccgtttg ccttgtaagg acaaactgta ggcaaggtct
    29341 aagccaatca agccggcacc aataaccaag acctcttggc tagcctcaat cagttttaaa
    29401 ctagcttggc tttcttcata atatttggtt accaaaactt tgttggtctg tgacgtctca
    29461 atataatgag actgggggct agcacccatg gcacaaacaa gcgtttcata accttcttca
    29521 aaaactcgtc cttgactgtc tttgagaagc aaggtgtttg agggagcttc gatagctaac
    29581 acttctgctt gaataaaccg atggttagac tctatttgtg ctgctaggca ggctcttccc
    29641 cacatagcat cagacaggtc ttgaatgtct cctctgaata attggttgat accatttgga
    29701 atataattgg gacagctttc cttatcaatg agaatgattt gggaatctgg attgaggtcc
    29761 ttatatttat caacaaaggt tagaccagca aaggatgccc cgataacatg tatggtcttt
    29821 gtcgttaatg tcataatagt attattatag cagttgtttt taagatatga aagcgtttta
    29881 cctaacccta taaagaaaat gcaaaggagc tggcctatga tagccaaccc ctttagtgat
    29941 ggttaggaca tgacttggaa aagcaaaact gctaaggccg ctccaataat tggtcctaca
    30001 acaggtatcc aagcataaga ccaatcagaa tctcccttgt tgttgagtgg tagaatagca
    30061 tgaactagac gaggtcctaa atcacgcgct gggttaatgg cgtaacctgt cgttcctcct
    30121 aaggataacc caatcccaat aaccaaggta cctacacaga gggttcctag tcctgctggc
    30181 atatcatata agccaaatgc caaaatacca agcatcaaga caaaggtccc aaagatttca
    30241 ctcaataggt ttgagctagt atctcgaata gcaggacctg tcgcaaatgt ccctaaaata
    30301 tcagcctgac tctcagcagc cagataatgt ggcctgaact gaaggaatac cagagttgaa
    30361 ccaaccatag ctcccaatag ttgggcaagg ctataggcaa tggctgttga ccaggcaatg
    30421 gttccactca tggcaaaagc aaggctaaca gctggattga ggtgggcagg ggcaactttg
    30481 ccactgataa agactgccac agcaactgca attccccagc cagtcgcaat cacgatccag
    30541 ccagaagcat gggttttcgt tttgggcaag acaacccctg ctaccacacc atttcctagt
    30601 aaaaccaata aggctgtacc caaaaattcg ccaaagatat ccatattaac cctcctgatg
    30661 gccttttaag gcactcaaat cattgtctgc aatcacgcga cgaagatcgt cttcttgtgc
    30721 cactctttcc tgatcagacc attcaaaatg tttagccatt tcattaatca ctgggtcaat
    30781 caaagcatct aggctatctc gcataaataa gaggtgattt gttcttctca agaaataatc
    30841 tgtcggttta agagccattt cataatccat cgcataatgt aaggacaagg tttcagctaa
    30901 acttaaccct tcagctgctg ttaattgacg agttaaggca aagacttttg gcgcattaga
    30961 accataaagg tttgccaaat acctagcatc atccatcgaa agaccactaa gagttcctaa
    31021 ttgagcatag gcttctattt ccgaatctac attggctgga ttgatttcac ctcctgaaac
    31081 aggataggtt tttgaattga taagcttgaa ggatttgcca aactcttctt tgaggatttg
    31141 aataatccct gtcaatgctc cttcagccat tttgcgatag tcggtaatct taccacctgc
    31201 caaggtaaag agtccattct catcacggtc aaaacttgaa cctcgtgaca ctgcagacgg
    31261 atccaattct ttttcagatg tgctggtttc aacctgctta atagcttttt caacagcttc
    31321 tcggctatct tcgtggttaa tataggcttt gacagtatca accaagtgat caaaactatc
    31381 atcactgact ttaccgctgt tgccaccatt gtagtcagaa gcactattac ctgataacaa
    31441 ggggcgaaga ccagcccaac tgctttcaat atcatcaatg gtcacgttgg catttggaaa
    31501 gcggttattg acaacgccta acaaataatc cacatcttct tgagtaactt gtgggtgctc
    31561 caagtctcca gtgtagtccg tgtccgttgt tccaaaataa gttttttctt cacgtggcaa
    31621 gacaaagacc atacgaccat catttaaccc tgtgtcaaca tagacaggtt gagacactgg
    31681 taatttttga cggtccacta ccagatgcac cccttttgta gggcgcattt gatgaatcgg
    31741 ttgtccctta tgagagaatt gacgaatctc atcactccat ggacctgtgg tgttgatgac
    31801 taatttagcc ttgataatga tttcttgatc tgacagcaga tcacgcgcct tcacaccaat
    31861 aatcttacca ttgtcatcta gcaagaaatc ttctgctttc acatgactag caataagagc
    31921 cccatcacga ttagctcgtt tgatattttc aataacaagc cttgcgtcat tattgcggaa
    31981 atcaaggtaa accccaccac caagcaagcc ttcttgtttt aagtctggtt ctcgttttaa
    32041 gacttcttct ttggttaaca ccttgttggc cgctggcgta ttggacacgc ctgctaaaag
    32101 atcatacaaa tccatagcga ccttcaaacg gaacatgcta aaggtgctgc caggttcgtc
    32161 ataaacaggt aataacatag ggtctggttt tggaatgtgg ggtgcaattt gttgcaccac
    32221 agcccgctct gacaccgtat ctgaaactac ctccacatca aattgtttca agtaacgaag
    32281 ccccccgtga accaatttgg ttgaacggct agaggttcct tgcgcaaaat cttgcatctc
    32341 aatcagaccc gtatctaggc cactagctgc cgcctgaagt gccacaccag cacccgtaat
    32401 acctccccca ataatcagta ggtctaaatc tctttcttgc attttttgga gagctaagcg
    32461 tcttgtttct cttgaaaatt ccattccatc ctcctctagt tattttgcat cgtcatctgc
    32521 atcttcttct tgggtgaaaa cttgagttgc tttaacagcg cgcttccaac ccttgtataa
    32581 tttttctttg cgcgattcat tcatgctagc cttaaagagc tggcctgtgg catttaactc
    32641 tttcaaagca tccatatctt cccaataccc cacagcaagc cctgctaaga aagctgctcc
    32701 tagagctgtt gtttctaaat ttttagcacg ggcaatatca attcctaaaa tatcagcctg
    32761 aaattgcatg agcatattat tcatggctgc accgccatcc acacggagct gttgaatgtc
    32821 aatacctgaa tccacctgca tggtatcaat aacatctcgc acttgatagg cgatagattg
    32881 taaggttgct ttgacaaagt cttctttgct ggtaccacgt gtcaagccaa agacagatcc
    32941 acgcgcatta gaatcccagt aaggagctcc taaaccggta aaagcaggca caacataaac
    33001 ttcatcgtca ctagttgatg ctagagcgaa ctgttcagat tctggtgaag tctcaatcat
    33061 tttaagacca tctcgcaacc attgaatggc agagcctgca ataaagatgg aaccttccaa
    33121 ggcatagtga accttcccat taatcccgta accaatggtg gtcaaaagat tattactcga
    33181 taactgcatc tcatcaccag tattcatgat aatgaaagaa cctgtgccat aagtgttttt
    33241 caccatacca ggctcaaaag ctagttggcc aaacaaagct gcctgttggt cacccgccat
    33301 acctgaaata ggcacttcgc ccccataaaa atgaaaggca gctgttttgc cataaatttc
    33361 agaattggat ttaacctctg gaagcatatc ttttggaata tttaaaagct ctaaaatctc
    33421 atcatcccat gttaagtctt taatattata gagcatggta cgagccgcat tggaataatc
    33481 cgtcacatga acagcaccat ctgtcaattt ccaaaccagc caagtatcaa tggttccaaa
    33541 aagtaactcg cctttttcag ctcgttcttg agcaccagga acatggtcta aaatccaacg
    33601 gatcttggtt gcagaaaagt aggcatcaat aacaaggcct gtcttttcat ggatcatttt
    33661 tgtatggcca tcttgtttga gttgctcagc aattggtgcc gtctgtcgtg attgccacac
    33721 aatagcatta taaataggta cacccgtttt tttgtcccaa accactgtgg tctcacgttg
    33781 gttggtaatt ccgattgctt caatttggct tggtttgatg ctggactcaa taaaagcacc
    33841 cgcaataaca gactgaaccg aattccaaat ctgattagca ttgtgctcta cccaaccagc
    33901 gtgtgggaaa atctgaggga attctttttg gctactgcta accttttccc ctttttgatt
    33961 gaaaataatc gctcgtgaac ttgttgttcc ctgatcaata gccatgatat acttttcttg
    34021 cgacattcat taccctcctt taagtaagcg ttttcctatt tgattctatt atagctaatt
    34081 ttatcagaaa tatattatca agaattttta aagctaaaaa aaagctgata agataggtag
    34141 cttatcccac tagatgatct tgaaaaatcc actgatgaca accacgtctc ctcatttcta
    34201 acgaggtaat ctttcttatc aaagaaaatc aaaagaccca acaatcactc tgctaatcca
    34261 gagtcatcat tgggtcataa agagaactaa gcctcaaagg caacacggta tcaaacagcc
    34321 gtgcctaaga ggcaaagaca attggacaca agagttaagg ctgtcttatt cattacagtt
    34381 cttgattagt cattgattgg ttcagaagat ttttccacaa tatcccctga gttggcgtca
    34441 atggtatagc tgtattcttg atctttgttt tgaaactcga tttcatacac ggctttgcca
    34501 tcttcattat cttgtgtaac tgatagcatt tgagcatcag cttccgtaac agaagcatct
    34561 tttaacgcaa ttgatttggc tttgtcttct gaaagtttaa ctttcttgct agtttgactt
    34621 gtctttggtt gattatccat atgatcgtct ttttcatcca tatcacaggc tgcaagactg
    34681 agtaaagaga ggctggctat ggctagtaga gagaattttt taattgtcat aagtactacc
    34741 ttctttcttt gatttcttct attataactc aaacacatgg tttttcccaa tattttgact
    34801 atacaatata aaaacgtgtg gtcactttga agtatcatac catttaaaat aaaagctaac
    34861 agtcatcacg ataaacaaaa agcagttcag agctgctttt tgtcttatga ttttggatca
    34921 tctaatgaac ggccgtgcaa gcctttttca cgttgcacct gtcttaattt ttcaggggtc
    34981 acgtcgtttc cttcttcgtc caccaatttg atgccttcga tatggtgtct gacagagcga
    35041 cgatagcctt caatgtattc ttcacggagt tttgcctgtt ccactttttc aggtccagtc
    35101 aagcctaccg tttttttctt tttagccagc tcattgatac gagcaatttt tttaggatcc
    35161 atgttaagcc actaagagcc tgggaaaaaa gtataaggct taaaaaactg acttgactct
    35221 cactgtgaaa agcaatgttt aaaggccttg ttttttccac tcgggtactg aactcacttt
    35281 tctagctaag tccccaacgg ctctttcctt tctatttact tggtgtttag ttggttaaaa
    35341 gcagcaatgg tcttagcttt gcttactaaa tctgataaaa tagctaaacg gttgttctta
    35401 agggattgat cttctgccat aaccattgtg ttatcaaaga aatcattaat cactgggcta
    35461 agggcaaaga cctgttctaa ctgctgggca gcactgcctg ctagagtcaa gccttgaata
    35521 gctgcaaaca aagtgttttc ttgctcattt tcaaagaggc tagggtccac ctgaacagaa
    35581 gcgtccgctt tttctgccaa attaaaagca cgtgacaaag attcaactgc tggtttgtaa
    35641 ttttccgtat ggctggcttt gacaagtgct tcagctgccg ctaacatttc aggaaccaca
    35701 aaggttgaac tctctaaaac tgcttcacga atatcttttg gtgcggcttt gcccatcatc
    35761 ttatccacac gagcacggat aaagttcatc acatccgcct tattggcata ggtcaaacta
    35821 tcaaaggaca agtcatataa gctatctacc agcttatcca ttgggatgcg ccatccaaaa
    35881 tgatcaagaa tacgaacgat accctgcgtt gcacgacgta gagcataagg atcattagag
    35941 ccagatggaa tcaagccaac agaaaagaat gacaagagag tatccaattt atctgccaag
    36001 gccaggacag cgccaacttt ggtttcaggt agcgcacctc ctgcagcatc aggtaagtag
    36061 tgttcacgga ttgctgttgc cacagcagca tcttcaccag ctagaaaagc atatttttca
    36121 cccataatcc cttgcagctc atcaaattca ccaaccatac ctgttaaaag gtcaaatttg
    36181 taaatttggg cagcacggtc aacagctgtg acttcctcag cagataggtt ggcttcctta
    36241 gcaagtgatg cggcaatgac acgcgtacga tccatgtgtt cagcaagaga gccgattttt
    36301 tcatggaagg tcacattggt caatttggca actaaatcag caatttgcaa tttctgatcc
    36361 tcacgccaga agaattcacc atcttctaag cgagctacca aaactttttc gttcccttta
    36421 ataacatttt caatggcttg atcattccca ttacgaactg atacaaagtt tggcatcaag
    36481 tgaccagcct gatcacgtac cacaaaataa cgttggtggt ttttcattga tgttaccaat
    36541 acttcttctg ggacatcaag gtatttagcc tcaaaacttc ccatgaaagc tgttggaaac
    36601 tcgaccaagt tcaaaacttc attaagcaag tcttcgtcaa tgtcaacttg cacaccctgc
    36661 tccacttcaa gcgtcttgat ttgctccaca atcatctctt gacgctcttt agcgtcaaca
    36721 atgacgcatt ggctgcgcaa atcagcctca taagaatcag cacttgtgat agtggtttca
    36781 gtacctaaaa aacggtgacc acggctgacg cgtccagaat gaatatccaa gaagtcaagt
    36841 tccaaggcct catcattcaa cagaactgtc aaggtgtgaa caggacgaat gtattcaaaa
    36901 ctattgttag cccagtgcat gctgactggg aaggtcattg ctgacaacac ttcagtaacg
    36961 cctagaagca cttccttagc aggttttcca gcttcgtgtt tggtcacata aacgtattct
    37021 tctcctttga cttcgcggaa ttcgatagca tctgtggtca agcctttgcc acgaacaaat
    37081 ccttgagcag cttttgagaa attcccatca gcatcaaggg caattttctt agcaggccct
    37141 ttaaagtcct cagtcaaatc cgtttgctga tcagctaatc cagacacacg cactgccaaa
    37201 cggcgtggag ttgaaaaggt ttgtatatct tcaaaagaga gacgattttc tgttaagaaa
    37261 gtcgccaagc gctctcccag ttgtttttca cttggtgtga ccacgtaggc tggaagttct
    37321 tccagaccaa gttcgattag tagattttta ctcataatta agataccaag ggcgttaagc
    37381 ggacaccatc aaaatagcaa agcgacgcag gtgcttgcac ctaggaagtc ttggtctttt
    37441 tgacatagtc cgtagcccgt gttcagttcc tttctctaaa aagtatcttt ttgattgttc
    37501 ccttaggtag gggggacgca aagtgaaatt atccagtgga taatttcaga aaacaaaagt
    37561 gttccattcc cagttagcca gcctaaagtc tcgccaactc cctcgttcga taagtaacct
    37621 taccgaattg tcactacagc gggagtaacc ttgactcggc gaccttcggt cgcccacttc
    37681 ttgctcgctc ttaagattac aaagctcgca actagatcat ctttaaatcg acttattcgc
    37741 catcttcagc tagcaagatt gcgcgtgttg cttcatccaa cagtggaaat ccaagcttct
    37801 tgcgttctgc aacaaaggtc ttagcaacga cacgtgccaa attacggata cgagcaatgt
    37861 agcctgcgcg ttctgtgacg gaaacagcgc cacgggcatc cagcaggtta aacgtatgag
    37921 aacatttgag cacgtaatca taagctgggt gaaccaaacc ttcttctagg gcacgcgagg
    37981 cttctttttc aaacttttca aagttttcaa gcagcatgtc ttggtctgat atttcgaagg
    38041 aatattttga atgctcatac tcaggttgta agaagatttc accatattta acacctggtg
    38101 cccactcaat atcatagacc gaatccactt cttgaatata ggaagctaag cgctcaagac
    38161 cataagttac ttctgctgtc actggagatg tcgcaaggcc accaacttgt tggaaatacg
    38221 taaattgtgt gatttccatt ccatcaagcc aaacttccca accaagccct gctgatcctg
    38281 ttgaggggtt ttcccagtta tcctcaacaa aacgaatatc atgttctaaa ggattgatgc
    38341 ccaatttttc caaagaagca aggtaaagtt cttgaatatt tgatggtgat ggtttcatga
    38401 ccacttgaaa ttggtggtgt tggtaaagac gatttgggtt ttctccgtaa cggccatctg
    38461 caggacgacg tgatggctct acataagccg cattccatgg ctcaggacct atagcacgta
    38521 agaacgtgta aggactcatg gtcccagctc ctttttcatt gtcataggct tgcatgagca
    38581 tacaaccctg atcattccaa tattgttgta aggtcaagat gatttcttga aaggtaagtt
    38641 ttttagacat ttcgtactcc tttgatagta gtaaaatggt atatcattga caatcgtttt
    38701 tttgtcatca gtaaaatacc tgacgatgtt actagcatgt attacaggtc taggcaccaa
    38761 aaaaccgcat tttgatgctc ctaaatcata agacctaggg gcgtcaaaac gcggttccac
    38821 cctaatttat tacttcattt atatagtatc tttttgggca atattgacaa atatacttaa
    38881 tcacactgcc caaacggaag cgccaatctg cagtcctacc attcggctct aactaccccg
    38941 aactcgcttt agataagata cttgcatcct ttttcctaga gtctagttta gcataaagcc
    39001 attagtttgt ccatcatgag cttaaggttt tgttcgagta ccgtttggaa taatcacttc
    39061 cgctaatagc ttgttttctt ctcgaatacg taaatatatt actacaatgt agcatgggaa
    39121 aagaagcata gccgtaattt tagcatggca aagtaaggct atgcccacca gctcaggggc
    39181 gatatttaaa aagtagttag gatgtttaat cgttttgaac aaccagtgat ccacatattt
    39241 gtggtctttt gctaacatca attttacagt ccaaatgtca cctaagatac gtgtcacttc
    39301 atataaaaca gctactgata ataacatcaa caaaagacct aaaaaactaa tgccatcaaa
    39361 cttaatttgt ttaagcagcg cttcaatcac cgcaaacaca taaatcataa tgtgaagtaa
    39421 cgtcaaaaat ttcgtgttct gagcaccaaa ttcctgtcct ccttgggcta atatggcttt
    39481 ttcatttgtt atcgatttct tcaaaaatac taaacgaata gtaaacatgg ctaacatcac
    39541 taaaaagatg gtcacaatac ggctccttat tttcaataat agtttctttc acaaaacact
    39601 aataaagatt atagctaaat gataaacctt tgtcaaaccg ttttcaaaaa agatttagcg
    39661 aattatggct aaatctttgt agtttcttaa aaacttgtag tatcagggtt aggaatcgct
    39721 gacattcctg agagatagcg aattgttttt ttatcttctg gtgtcaagct cacatcaaaa
    39781 atagccatat tttccttgat gcgctcatca tgcaccgatt ttggcaaggg aataaaacct
    39841 tctgccagcg accaagctaa ggcaacttgt gccactgttt tgtcatattt attagctaac
    39901 tgctgcatag tctcattatc aaaaatctcc ccttgtccta gaggactcca agcttccaat
    39961 aaaatctcat ttgtcttaca ataatcaacc acttcctttt gatagcaacc tggggctaat
    40021 cgaatctgat taattgctgg agttatttta gctgtctctt gaagagcttc tagatgatgc
    40081 accataaaat tgctgacgcc aatgctttta ataagccctg cttcaaccgc ctcttccata
    40141 tattgccatg cttgggcatt tgcctctttc caagtgttac gcagagcttt tgggtttggc
    40201 caatggataa gatagagatc cacataagcc agaccaagac ggccaagaga agcagctaaa
    40261 gcgtcttttg ccccttcata actatgggcg tcattccaga gtttagttgt aataaataag
    40321 tcttctcgta gaaccccaga atccttgatg gcacgaccca cactttcttc atttttataa
    40381 atagctgcag tgtcaatatg acgatagcca gccttgatgg ctgctaaggt agattggtaa
    40441 gcttcctcac catcggctgc ttggtaagtt ccaaatccta aaacgggaat ctcatagcca
    40501 cttgtcattt ttactgttgt taccatcaca aaaacctcct tttatcaatc tctgtaagcg
    40561 attactttaa tctattctat cataaagaaa gaaagaaaat acaaaaagaa ttggcctgcc
    40621 agacatagct accccaatcc ttttgtatct cttaggcatc aaaagctttt tgcccattta
    40681 aataggttgc aacaagtgtt aaatccttat caagaacaat aaagtcagcc gcatgcccag
    40741 ctttgatttg accacatacg tcgtcaatac cgacagaaac agctggcaca taggttgcca
    40801 tatgaatggc ttctgccgga gttgcgattc cccaggccac tacatttcta aggccgtctt
    40861 ttaatttcaa aatagatcct gccaagtttc cactctcttt aagacgagca gtgccatttg
    40921 ccacaaccac agagaattcc cccaagaggt aatcaccatc tggtgaacca cctgctcgca
    40981 tacagtccgt aatcatggct acatgatcat gccctttttg ctgcatcaaa atatcacaag
    41041 caattggtga gacatggtgg ccatcacaaa tcaactctgc gtaagtattt ggaagattat
    41101 aaaccgctcc caccattcct ggttcacggt gggtcaatcc tcgcatgcca ttataagcat
    41161 gaacccaaac actagcacca gcttgaacag cttctttagc ctcttgataa gtaccgtttg
    41221 aatgccctaa ggccactgtt acgccttgtt ttgtcactgc ggacacaaat tctttgacac
    41281 catcacgctc aggagcaagg gcaatttttt tgatgagccc tttagcggct ttttgccaag
    41341 catcaaattc ctccaagcgt gggtttttca tataacttgg gttttgagca cccttatatt
    41401 cttcggtaaa ataaggacct tcaaagtaaa taccttgtat tttagcacct tttacctgat
    41461 cagcaactga agcaatagtc cctgatactt tttctaactg ctcaaaggta gaagttaagg
    41521 tcgtcggtaa aaaagacgtt actcctgttg ctaatagtcc ttcactcatt tgatgaatcc
    41581 cttgggcaga attatccatg acatcagctc ccgcatagcc atggatatgc gtatccacaa
    41641 gacctggtgc aatttgataa ccggtgtagt caatgatttg cgcatctgcc ggaacaattt
    41701 ctgtccactc cccaaaaaca ccatcatgaa gacctaggta gccagccggt ttcacctctg
    41761 ttgggtaata aaaacaatct gctttaagat agcatgtcat cttttttcct cccttttttc
    41821 cttattatac gccttattct ttactttgta aatggtatat accacttttt ggattcaaaa
    41881 aagaaaacgt ggatgatcat tcacgttttc tcttttttta aagctggtgt gaaagtactt
    41941 tctctgctaa attcaaggcg tgatctgtga tgcgggtata gtgggaaata atatcaataa
    42001 aattaatacc tgcttgtgcc gtacattctc cacaattcaa gcgcttaatg tgggttttac
    42061 gtaatcgtcg ctctttttct tcaatttctt tatggcgagt cacaatagtt tgcgccaagt
    42121 ctgtatcact atcaacgata gctctaatgg catccagtgt taaacaatgc gtcaattgat
    42181 acatctctgt caattcttga cgagcagata ttgaaaaacc aatttgttta gatatgatgc
    42241 cttcaattag aatacctaaa gactcagaat gatctccaat tctttccaaa tcacgtgaag
    42301 agtcaagaat accagccaag acttcatttt cacttgggct gagggcttcg ttagaaatat
    42361 caaccaaata agtggttaac tcctcatcga tggtatcaac tgctctttca taacgcttga
    42421 ccttttcccc aaatttatcg tcagctgtca taatataact gtaagaagct tcaaaagctt
    42481 gaatcgcata agaggctaaa tgaaccaatt ccttgtgggc atttcctagt gcgatagaag
    42541 gggcttgggt aataagtaag cgatctaaat aaagggcttc gtatttgacc acttcatctt
    42601 ctcctggaat gagtctagtc acaatcatag ctagtagact aatgaaagga attaataaga
    42661 tggtattagt gatattaaaa gagccgtgag aaaaagcgat agtcatctca ggtgttaaac
    42721 tcaactttga ttgtagccat aacatcaatg atgtgaatgg gactaggata atcataaaaa
    42781 taattgtacc gatcaaatta aataacacat gagctgctgc cacacgttta gcagcaatat
    42841 ttgaacctat agctgctaag acagctgtaa tgcaggttcc tatatttgag cctaacaaaa
    42901 taggaatagc cccctgtaag gtcaaaagac cgcctgaaaa cagaccctgt aaaatcccga
    42961 taatggctgc cgatgactga atcaacatgg tcaaagccgt tccgataaag acaccttgga
    43021 agggtttatc acctaatgtc gctaaataat tttgaaaggc tgacacagat ttcaaaggat
    43081 ccatggcatc tcccattagg ttcagcgaga agaaaattcc tccgacacca aaaatgatac
    43141 gcccaaaatt gttgagcttt ttattagagg taaagaaaag acaggctgca ccaataaaaa
    43201 tcatgggcaa ggcgtaatct cctagtttaa aaccaattaa aaacgaagtg atagtcgttc
    43261 caatattagc ccccataaca attccaatgg cttgtcgcaa atttagcaaa cccgcagaaa
    43321 ccaaaccaac cgtaatcaca gttacacctg aactggactg aattaaggca gacatggcaa
    43381 ttccgactaa gataccaaaa aagggattac tggtgtattt atcaatgtaa taccttagtt
    43441 tatctcctgc tgcttgttgc agaccatctc ccatatactt gatactgaaa agaaagagac
    43501 ctaagcctcc aaagaaatga aatgcaatgt cttgccaatt tactgacaca atattgtcct
    43561 cgctcaattt tttagtctat tctattttaa tgtattacgg tctttatcac aaggtttttt
    43621 taagcgtttc tgtgtatacc gatgtcaaca tttgcatatt attggtttga taaggtgtta
    43681 ggcttttccg atattttaca tcatttgttt ttgcacaaat cttttcattt cgtttaatta
    43741 gaggtataat atggctacga tgaaacaata tcataaagga gattccatga ctaaatcaca
    43801 aaaagaggcg ctttattgga tgttgagtgt tctaactatc actctaatag gtggctcctg
    43861 ccttattttt ggatcctacc ctcaaacgca agataaggta gctaaacatt ctaaaagtgc
    43921 tgctagttta ctaaaaaaag cagttaaagc agttaatgac gctgatcgtt tagccactgc
    43981 agctgctatc caagaagccc agaaagctgt tgataaatta gcagaatctt ctaagaaaaa
    44041 aacgctacaa aaacagctaa acgttgccaa agcaaagcaa gagcaagaag atgcagctac
    44101 tcaagcagtt aaagctgctg aggagactct caatcaaaat cttaaagata tcgcccaaaa
    44161 agcagttaac gacttaagta acaaaggtaa aaaagccgct ttacaatctc ggttagacgc
    44221 tattttacca gcgaaaccca ttattgatga atttccaaga caaagtggag aaataacaga
    44281 taactcttac tggacacctt tcccaggaga cgtctcagat acttatgata attcccagtc
    44341 acctacttta gacccaagct cagaatcttc agcttcagat gttacgccac aacctagtca
    44401 tcctgatcca attccacctc agacctcttc agaaccttct gactcaggag acaagcaatc
    44461 atcaaaagag taatacaaaa atttttcgta aaatcaatca ataaacgttt tagacggcta
    44521 tcttagtgat tagtcctcct aacatcttaa aaaagctagc tcaaatcaaa agagtctagc
    44581 tttttgtttt gttagatagc attaaatttc gtagcccatt aaaagtcctc cgtcttcagc
    44641 ataaaagcta cacaagcctg aggtccttcc agtttgaatc acagcatcag gatataaaga
    44701 tttgattttt tcactgatct gctcacaaat ttttggattt tgagcatgag caatgtaaac
    44761 ttttccgcct acataaccct ctttttgaat ttcttctatc aaagcagaaa ctgctttttt
    44821 ttgaccacgc gctttttgaa gaagttcaag cgttccttta ttgctagctt tcccaaccat
    44881 tctaatattg agtaagccaa ttactttacc tactaattta ctcagtcgac catttttaac
    44941 caaattatca accttggcaa gcacaaaaat caaacgtgtt ttttgctgat aagctgtgat
    45001 ctgtttgaca acttcttcaa aggataatcc aagattgatc aaccgctcaa gctccagtac
    45061 gagcaaatcc atctcgccac ctgctgataa agaatcgatt aggtgaatat tgacattagg
    45121 attttcttca agaagttcat ttttagccag tcgtgcacta ttatgactgc cagataaggt
    45181 ccctgtaatt gtcatcacga taacattatc tgcacctcta taggcctgta aaaaggcttc
    45241 tgggcttgga cagctagatg tcgttgcttt agacgactgg tacatagttg tcatcatatt
    45301 atcgatatct aatccatcat catctctaaa aatttctgtg ccaatctgta gggtcaaagg
    45361 cacacgttca aagcgcaact ctttggattg tctagtcaaa cttctaagat cacatcctga
    45421 atctgttaca attttccaag tcatttttta tccttctttt tctctaattt gtgttcggta
    45481 acaaagacca gattattaag ccttcgctaa gatgcctagg ctaatggtaa taactagtca
    45541 ttaaatccta tgttttatta ctagcctttt caatagttag taaagtcatc taatagagct
    45601 atacaaggag gtaatgaggc tcctgataac taactttagt tgacaaacta agacttttcc
    45661 cataaaatta tatcattatt aagtcggttt ttgctactga taactcatca gatgtaacac
    45721 ttgaaaggta tttgtgatga ctgataaagc actctcaaaa agatcacttc aaaacttaac
    45781 acaatttaat aaagaaacac gacgcatagc acgtgaatct atggaaatcg ccttactaaa
    45841 tcttctagaa acaaaacctt taggtgatat tacgatttca gaattggtga cgaaagcagg
    45901 agtatctcgt aacgcttttt atcgtaatta tacctctaaa gaagccatta tagaacaact
    45961 gttagtaggg gttatccgtc gtatttttcg tggactaaaa caatttgata ttaaaactca
    46021 ggcttatcaa gcctggctct atctttttac tgaagctaaa aaagaagctc agcttcttaa
    46081 aatgattttc aaacatcacc tgcaccatct tctaacacga ttagtcacta aacgtctgaa
    46141 agcttatcaa aaattaaaag acaaaaaaca atcgcactat aagcgccttt tttggagcaa
    46201 tgctattgtt tctgtcttga caaactggat ttcagatgac atgatcgttc ctgccgaaga
    46261 aatggctgct atgggcttgc ctctattaac gtaaaaaggt tccttttggg aacctttttt
    46321 atataatagt tagtcttttt gagctgcaag tgcaaactga cggatagcct gggccacacc
    46381 cgccatatca ttagtcaaag tgactttgtc agctaatggc ttgatagctg ctgaagcatt
    46441 ttccatagca actcctaaac cagcataagt taacatctca atgtcattgg gagcatcccc
    46501 aatagccatc acttggtcag cagttaaacc caaatcttct actaattctt tgagagccga
    46561 tgccttgctg actccctgag ggagaatttc taaaatatta tcttggctac gaacaacatg
    46621 aaaactctga ctaagctgat ttctcaccgc acgttcaaag gcatctagcg cagctttttc
    46681 tcctaagtac atggcttgaa aaatcaggcg aggagtgtcc gacagctctg ctaaggagac
    46741 aggcttgaca atggtaaata ccaaatctcc atcttcctgc acaaggtctg gcacttcttc
    46801 ttcaagcacc aaataatcgt tttcctcagt taaagtcagg taaatatctg gaaaactttg
    46861 gcttagctct tccagcaatt caatatctga aaccttcaac atttttgaat ggcgtaattg
    46921 ccagtcagga ctactataag tactacagcc attattgata atgaggaatt cctcttgtgt
    46981 caaacctaat tggtcaaaat agggtcttgt ccctgactga ggccggcctg tgcataagac
    47041 aatttttaag cctgactgag ctgcttcttg gatggctgtg atattctctt ttggaatctg
    47101 tttgtcctgg tttaataagg tgccgtccaa atcaattgca attagttgaa tcatcctatc
    47161 tttcctcttt ccatttgatt ttagggaggt tccatttttt acggttgcca atcatgcgta
    47221 aagtcgtgag taaaacaacc aaggcataac attcaatcgt tgaatctgct agtttaaaat
    47281 gcaaaacaat agctgcaaga atagaccacc cagcatagat ttcactacgc aaaacactag
    47341 gttttcgccc tgccagaata tctctgacaa caccaccgcc tgcaccagtc aacacagctg
    47401 ctacaatgac agcacttaaa ggctggttaa gacggacagc atgcaaggct ccttggacac
    47461 taaaagctgc cagaccaatg gcatcagtca aaacagctgc ccgtacccaa cctctagcca
    47521 ttagcttagg aaaaagcata atcaaaacca tagcaaagaa agcgcaagtg aattctggct
    47581 tttgccccca taaggcctct ataggtaaac caattagggt gtttcgaatg gctccgcctc
    47641 caaaggctgt cacgaaacct aaaataaaaa tccctaaaat atcaaattct tcttccatgg
    47701 caacaatagc accagaaaga gcaaaggcaa tggtcccgat gatatttaaa atttcccaca
    47761 tatcaattgt cataagctac cctattgtct tttagttttc ttttagttta ccacgttttc
    47821 ctttaaaaaa taagtagaaa aagataaaat gtaaggataa aaaagcaagg ataaaaccca
    47881 ttttcatcct tgctacaaaa gattcaaaca attatcccca tacttatctt atcacatcaa
    47941 tgagagctgc ttgataggat aaggttgttt tagatttttt ccgtccaagg gctagctgtc
    48001 tcttcgagta ccctgtttaa ctcgtcaata ttttggaagc cttcagtgca tagccacttt
    48061 cttgcttcgt cctctccttt agtaatataa actggaacgg atcctgccca cgtggcacgc
    48121 ccacacaaaa caccgctaaa ttgagcacct gctgctgctg caaagtataa tgtctcttga
    48181 aaaagtttgg cagatacgcc tgcactcaaa tagatataag ggaggtggct ggcagcttct
    48241 tggtcttgaa aagctttaat tgcctcagct tgactgtaat ggacttcccc ttcagtaaaa
    48301 ccttctacat aagccatatt aacaggaacc tctactttta gcacatcaac gccaaaacgc
    48361 ttatccgaaa atactgacat agcaccgtta accttatgtg gcttaagctt tgcgtatgcc
    48421 gcactgttgt tatctgatat tctctcatca taactcaaaa gttcaagaaa aaaagggatg
    48481 tcttcagctg tacattctga accaatacgt tcaatataag cttgtttttg taaattgatt
    48541 tgttcatctc catcaacatc ataatagagc aaaaatttaa tagcatctgc acctgctgct
    48601 ttcaaccgtt tgaccgacca ttccactaag caatcgggta aacggctagt ggttgtagca
    48661 tcataacctg ttttttcgta agctaacagt aagcctgtct gattagcttt taccttagta
    48721 gccagcaacc catattctgg atctaataaa atagatgaag cataaggcgt caattcctca
    48781 gaaacgagaa ctttcaatgt ttctatctgt gtaactgtcg cttctccttc ttgatgtgct
    48841 gccatcattt gcttcagtgc acctcgttga tcaaaagcta aagctgatat gattccttga
    48901 tggctcactt tttctaagta atgtctttta tttgctgtga ttgtcatgtg atacctctct
    48961 tacttgaagt tgctgatata attgtttaaa agttgccata gtcatcaaat cttgataata
    49021 gtgagtagct agtctcttag gcagactgcc tgagaagtta agacatcaaa cggcttagca
    49081 atagtactca tgtggctcaa agagacttcg gcttcgtcca catcactgta gggaccagct
    49141 tccaaaattt ttgtctgcat gccttcatgt aaaacagcaa tacaatttct cgtttcccct
    49201 ttgattttga aaaattggtt agaaatgccc tgttcttgta actgatgaat gataaagtca
    49261 cccagtttac caccactaaa tcctgttgcc ataactgacc agcttttggt cacatttagc
    49321 tccttatcac cagctgtttt tgccgttctg tcaacacgat taaccgtgtc catagccaga
    49381 caatctaaag gataggaaat agcgacagaa ggatttaaga taactgttaa actcatctct
    49441 tcttcctaat cgtgatactc accacggtcc catttttcta aaaattctgt aaagaaatca
    49501 ggatcttctt ggttggcatg atgactttcc aagtgggcta ttttagcaat tagcttctta
    49561 ttctcttcag tttctttgta ttctgccttg ataaaagcat ctataatatc acacataaga
    49621 agttcaccag tgattttacc accaaagcca atcacattgg cattcaattc ttccttggca
    49681 taaagcgctg ttgtcatatc tcgaacaagg gctgaacgaa tacctggtac cttgttcacg
    49741 gcattattaa tgccaactcc agttccacaa atacaaacac ccaagtctgc ttgaccacta
    49801 accacagctt cgccgacttt ttttccaaaa atagggtaat gggttcttgt atggtcataa
    49861 gtgccacagt caataacgtc atagccttta gatttcaaaa aatcagaaac agccattttt
    49921 tcgttggtga caatatggtc acaaccaatc gcaattttca tcactttatc ctcctttagg
    49981 ccattttatt gagcatgtca acacgaattt gatgacgacc accatcgtag ggaccagtca
    50041 caaaaccttt gacgatattc ttcgctaatt ctggacctac aatctctgca cctattgtga
    50101 tcatgcgggc attgttgtga ccgcgcgtca tgtaagcaga gcgttcatct gacacttcag
    50161 cagcaaccat tccttttaat tttgtggcta ccataaaggg acctgctccg taagcatcca
    50221 ccataatgcc taaacgccct tctgcttcat taacggcttt agccaccgct aatgtgttat
    50281 caataaaatc actgttaata tcagtcacgt caataatgtc atagccttct tcttgaagaa
    50341 aacttttgat caattctttt aatgcatttc cgtgtgcatc tgcacctaaa ataatagcca
    50401 tcgtttctcc ttttctaatc caaaccgctt gccaatctac aaaaagataa caggattacc
    50461 tgtcattagg tcaggattat tgccagtagt cttagttgtc ttccattatt tctttcaaga
    50521 caaagcactt gtgggttccc acagagcgcc ttgccttaca tgagaaatac tcttttcacg
    50581 ttagggagta aggtagaaat accttacgca gttatctgct attctcccta attttttagt
    50641 cagtcacctg acctgatttt atgtcattgt tttcgcatac tcagcgttac gtgccttcat
    50701 ttggttagca taccaagcaa agagacctag gtaaatggca ataaagatga ttagcgtgat
    50761 gattgaggca atctgacctg ttgtcgcttg accaatcaca taaccaaaaa ttttttccat
    50821 tggtccttca agtgttgaat gcgtaatcaa ggaaccagcg cttgtacctg ctggaaaagc
    50881 ccctactttt ttagccaact ctgtcgcaaa tggagcaatc atagttcctg acaagaggaa
    50941 taatggcaat aagagggaac caaaaataat catgcgaatc aaacgaccac gtgtgaccac
    51001 aagaagagct ggtgtcatcc ccatagcaat aattcccgcc aatggtaaaa tcccattgcc
    51061 aacttttgat aagagaacgg cttcaatcaa catgattggg gcaagaatat tggcacaggc
    51121 ccagatttca gcgcgaccag caatgaaggg ccagtccaaa ccaatattga aacgacgtcc
    51181 atgcattcta gcattggcaa aattggtaat cccttgtgac aaaggctcaa cagctgcgat
    51241 aaaccaagaa ccaatcaaag agaaaagttc caaacaggca cccgctgtaa atcctagacc
    51301 aaaccaattt ttgatagatt caacagtgaa atgagggtct cccataatgc caatcacaaa
    51361 acctagagcc attccgataa aaaacttaga gccccagaag ccaatttttt tgttcaattt
    51421 agcagcatca aagtcatatt tatctagccc cggaaagacc ttgtcaaaaa tcttatctaa
    51481 gaccataatg attggattca tcatgtagtt catgtgagtt gaagtcattg gtgattgaga
    51541 ccctgtccca agaaggtcat caaaggtcgg tttcatcaaa tcagagttaa tgattttcaa
    51601 taccccaaca agaataactg ccacagtagc aatcaaaaga gacacaagga ctggcaaatg
    51661 gttgtgatca gcataccaca taatcaatag acctgtgata gacaaatgcc aaatatcaaa
    51721 aatatcgaca tcaagggtgt ccgttttttt catgacaatc atgacaatat taaccaccag
    51781 catcaccagc aagaaataaa gggtataagg ggaaccccag gtaattgttg caagcggtgc
    51841 ccaaccgaca tcaataatat tcaaactgat tcctgtattt ttgacaaagg cctgcaaaga
    51901 ctctgaaaaa gcccccgtca aaatcccaat aatggctcca atacctgtaa gagcgatagc
    51961 taacttaatc ccgccttcca gtgcctttgt gaatttaacc ccgaaaatca tggctaaacc
    52021 tgtcatgaca atcagcatga ccacacctga tcccaactga ataggaaatc ccagaatctt
    52081 gttaataatg tctaaaaaag gttgcatcat cttgtctcct tatgttttta ttaactcact
    52141 gcaaatggtt ttctttaatc acgcgctcta attcagcaaa aacaggctca ctcatgattg
    52201 ggatacgata gagaatcggt cctgcttcta ctgtgggaat tggcatctca aatcccaagt
    52261 cagtttttgc aatcggcgta aaaatatcat aacgagacac caattcttct gtgatgtctt
    52321 tgaccatcac cgcatcacaa tgcacatcat agccacgatc actcatctga gtttcaatcg
    52381 catctttaat ttgatggctt gagttaaccc ctgcaccgca ggctgctaga attttaatca
    52441 tgctgaaaca ctcctttttc tattaaatag tttgaaatag cttgtttatc atcttttaga
    52501 ctggctagat agctaagatt gcctttcgta ataaagaagg taatgagatt ggatagaatc
    52561 gtcgtttgac cctcgttttg actattgata ataaagaaga gatccgttac caaacagtct
    52621 tcctctggat taatcatgtg cttaaaggta agggcttgac tatttctaac atagaccact
    52681 tgatcaacca agcaatactt ggtttctgta tgcggaatag ccgcatacaa aatatctgac
    52741 ccatctttga ggtccacttt gagtcctgtc ggaaataccg cctcacgctc cactaaagcc
    52801 tgatggtact cttgcgtcac atacccaacc ttttccaagt ggctagcaac aagatcaaaa
    52861 agctctggct gcgtccttgc ttcagtaaat agaatattag gaaacactcc ctaccgcctt
    52921 tctataagta tcaattttta acaactgtca tctcatcatc aacaaattgg taaccgttta
    52981 caaaatcatt atagtataac cttcaacata attcaacatt tttacgcaat attttttgtt
    53041 ctatatgttt gtttttgttt tgtttatttt gttttattga aatatgaagg tctatatgct
    53101 atgataaaca taagtaaata aactatagaa aggagcccct tagatgttaa aaagagaaag
    53161 acttctaaaa attaccgaaa tagtcaatga gcaaggtatt gttactgtga atgacattat
    53221 tcagacttta aacgtttctg atatgacagt tcgtagagac ttagatgaac tggaaaaagc
    53281 cggcaaattg atccgcatcc atggaggtgc acaaagtatt accatgccta ataaaaaaga
    53341 gcggtcaaat attgaaaaac aaaccgttca aacaaaggaa aaatgggaac tagcttcata
    53401 tgcgacacaa ctagtcaatg atggtgaaac aatctttatt ggtccaggaa caactttaga
    53461 atgtttcgct gagcaattaa aaaatcgtca gattcgcatt gtgaccaata gcctccctgt
    53521 ctttaacatc cttcaggaca gcgaaaccat tgacctgatt cttatcggtg gtgaataccg
    53581 atctattaca ggagcttttg tagggtccct tgccagtcaa aatatctcat ccttaaaatt
    53641 tgccaaggct tttattagct gtaatggtat ttataaaaac gatattgcaa cttatagcga
    53701 aactgaagga gagattcaaa agctagcttt taataattct attgaaaaat acctcttggt
    53761 agataaccaa aaattcaatg cctacgactt cttcattttt taccatttaa acaacattga
    53821 tgctgttgtt acagattcgc aaataactga ggacgtcatc gaacgttata gtcagttcac
    53881 gcaattatta gtagcccacg aaaacaagga gtaaccgttt catcaagaat ggacagcctg
    53941 tcagcgcatc gtccttaaac accttctggc aaaagtgatt tgcccccaga gaggtgtttt
    54001 tgttttgctc ggaacacacc tgctaacgtc agagtcttta tgagtgacca caaaaaaaga
    54061 agcccagatt aaaaaactgg aacctctttt gagatgaagt aaggctacca aaataaccta
    54121 agaccattta tgtaattcaa atttggtatc cttcaaagca cgcttgagta ggaacgttaa
    54181 aggacgtcct gtcaccttag cctgtccttt ttccaaattt acctggaccg attgcacacc
    54241 ggggacagct gataattttt cagtaaccgt tcttgcacaa ccgtcacacg tcattcctgt
    54301 aacctgataa tgtttttcca tttcgttttc tccttcaaat ggtttttcct tttaatcgca
    54361 gggcattcaa aacaactgat actgaactaa aactcatggc aaagcctgct aacatcgggt
    54421 tcaatagtgg acctccaaaa agatgaagta agcccatggc cactggaatc atgaggacat
    54481 tgtaaatgaa tgcccaaaat aaattttcct tgacaatcct catagtcgct cgactcaatg
    54541 acatagcttt caccaaatcc agcatatcag gtttcatcag aatcacatcc gccgattcaa
    54601 tggcaatatc tgtccctgac cccatagcta tcccaatgtc tgctacagcc aatgccggag
    54661 catcattaat accatcacct accattgcaa cttttctccc ttgagagcgg aggtctgcta
    54721 tcacgcctgc tttttgatca ggtaagactt gactgatcac atctgtaatc cccacttgag
    54781 aggcaatagc cttagcggta gcatcgtggt cacctgttag catgatggtg tgaattccca
    54841 gttgatgcaa agcttcgacg gtagcttgac tatcttcttt gacagcgtca gcaatactga
    54901 aaagagctcg tagctgcccc tctttagcat aatatacaag ggtttggcct tttcctgaag
    54961 ccttagcaca aactgactga acacaagata aatcgatacc aagaattccc attaaagcag
    55021 catttccaat cgccaaacga cgcccttcaa gctgaccagt gactcctagg ccggttaaag
    55081 actcaaactc ttccactggt agactatcgt aaccagcttc ctgagcagca cgaacaatag
    55141 cctcccctaa ggggtgttga gaataggcct ccaaggaagc agcttcttgc aagataaggt
    55201 gatcatctcc cgaaaaaatt aggagctttt gaagacttgg tttcccctcc gtaatcgtcc
    55261 ccgttttatc aaaaacaacc gtatctacct gatgggcttg ttctaagatg tcaccacctt
    55321 taaaaagaat accattttca gctgcacgcc ctgttccaac cataatcgct gtcggggttg
    55381 ctaaaccaag cgcacaagga caagcaatga ctagaacagc gatggctgtt gtcaaactaa
    55441 aacgaagact ttcctgcatg aataccaacc aaaatacccc tgttaacaga gctaatacca
    55501 aaaccaccgg aacaaagaca cctgagactc tatcagcaat agctgcaata ggtgctttat
    55561 tttcttgagc attctcaact agttggataa tttgtgctaa caaggtatca ttcccaagct
    55621 tatctggttt aatcgtgagg gcgcctggcc cattcaagct gcccgcaaag acattatctt
    55681 tttctccctt ttcaacaggc aaactttccc cagttaaaaa ggattcatcc aaactgctat
    55741 gtccttccac gataataccg tcaatagaaa ctttttcacc tggttgaacc aggacaaggt
    55801 catcatagct aacttcttct aatggtaaca attgccattg gctgcttctc cataccctca
    55861 catcagtagc cttcaaggat aggagctttt gaatagcttg agaagtacgg cccttagaac
    55921 gactttcaaa atactttcct agaccgatga gtgtcaaaat cactaccacc gattcaaaat
    55981 aaagggagtg cacaaagtgc gcctgaccca aactgatttc aaccactcca taaagactat
    56041 aagcaaaagc aaagctggtt gctaaagcta ccaaggagtc catattagga tgtcccttaa
    56101 acaaagcttt aaacccatta tggtaataat gacgatttaa tactaagact ggaatcgtca
    56161 agagtagctg actaaagctg taaatgaaag gataccaatc tggttgcata aatggaggaa
    56221 gccataagcc caccatgtga cccatagcta ggtataatat aggaatggtg aatagggcag
    56281 accacaagac ctgagaccaa ataaccttta ggtcttcgtc acgacgacct gtttgcatat
    56341 gttttgcatg ttcatcaaag acttgtgcac cataaccagc agcttttacc gcttgaataa
    56401 ctttggccgt ttctaaatcg tcatcttgat aagtaaccgt gagtttctcg gtcgctaaat
    56461 tcacaacagc ctgttctact tcaggcaatt gattgaccgt tttttcaatt gttagagcac
    56521 aagaggcaca actcattccc tccactaaaa atatctcttt agccattaat acgtctcctt
    56581 tttctgacag tggcactgcc caggcaggca attacacggc acctcaagaa ctgcattttc
    56641 ttttttgact tctagtagct cttggaatgc ctcaatttcc tctaaggtca tcggtaagtc
    56701 ataaagccgt tcaagaagta ggcgcgtgtg ttgccgctga caaataccgt ctaaaacagt
    56761 cgctagtgct tctttttgta ccaaagtctc atccaaaaga gcttgataaa tataggccct
    56821 accttcccga taagatgtta aaagattttt tttaactagc ctaccaatga gggtcttaat
    56881 agtggaatct gaccattgat attttttcct taaaatagta ataatatcgc tacttttaat
    56941 atcaccactg gcccacacca cgcgcatgac ttcccactcg gcagctgata tctgttgcat
    57001 aacgtcacct tcattcacaa tatatttacg tttgtaaatt aattataacg aatttaacta
    57061 catttgtaaa taaataactt ttctcatttt tctatcctta tattgacaaa tgaatcgttt
    57121 ttactataat attattgcaa taaaaataac atttacatta aggagatacc cttgaaacat
    57181 cctattcgaa aaacacttgt caccttaggt ctattactga ccttatgcct gccgactcca
    57241 gttgcagcta gttctcgttc ttggaagagc tggtttatcg agcaatattt ctggttaaaa
    57301 cgtgacaaga gttactattc taaacaagat gacccaagct tccaaagata ccttgatgcc
    57361 tgtcgtgaac aatctgataa accttatcaa ctagatacta atttagtcaa tggtcccctt
    57421 gttcaagaaa atctttatgg catgcaggtt tactcttgga atgataatgg aaaacctgat
    57481 caaaaaacaa ttatttatct tgccggtggt tcttatctta acaatccaac gacataccat
    57541 attaatatgt taaagacatt atccacaagt cttgacgcta aaattgtttt acccatttat
    57601 cctaaagccc cacgttatac ctataactat actatgccaa aattggtcaa tctttaccaa
    57661 cactattacc ataaaaatca gaatgttttc cttatgggag attcagcagg tggaggttta
    57721 gccttaggtc tagctcatgc cctacacaat gaatcagtcc ctcaaccaaa gcagctcgtt
    57781 cttttatcac cttggttaga tgttactatg tcacacccag agattccaga atacgaagat
    57841 gctgatccta ttctatcttc ttggggatta aaacgagtgg gagaattgtg ggcttactct
    57901 gctgataata ccaaccatat ttatgtcagt cctaaaaatg gtccgatcac ttatctacca
    57961 ccaattactt tatttactgg gacacgagag atcttttatc ctgatattcg cgattatgcc
    58021 gcaaaactga aagccgctaa ccacaatatt acctttatta cccaagaagg tatgaaccac
    58081 gtttacccaa tttatcctat cgaagaggca aaaacagctc aataccaaat cattgatgcc
    58141 atcaacaaga ctcctcaatg aggggaataa ttcctaactg ccaccagtta atctggtggt
    58201 tattttgtag tttgcaccac aaaataacaa ttaaaaagag ccctatcata atgataaggc
    58261 tctttctgtc ataacatccg caccgcaata cttaggactt gttgtcaagt tctcgtaaga
    58321 gttgatcaat tttattacca taggcgatgg aattgtcttt ttcaaacacc aaatctggaa
    58381 ttttgtacat ggtcaattgt ttgccaagtt cacgtttaat cgttccagtc gctttttcaa
    58441 gccctgtttg tgctttttga ttatcagatg ccaagtcact cataatagtg taataaactt
    58501 tagcaagtga caagtcaccc tgcatttgca cttctgtaat ggttactccc tgaacgcgtg
    58561 gatcacgcac ttttttctga agaatatcat ttacttcgcg cttgatttcc atcccaacgc
    58621 ggtcaatacg atgattagcc atagccattt cctttccaca tttttaaaac aaaagctagg
    58681 ctgaaagccc agcttatgac attgctacct gttttgataa cgacaattaa agggaatctg
    58741 agaattccat gacgagactg gaaggagtgc cccaagtagc tcatctggta gaacaagtca
    58801 ttatttccga cagaggaaaa acgttacatc tcagaccttc ttaaccccta ttttctcaca
    58861 atttcttcca taatataggc ttcaatagta tcgtcaactt taagatcgtt aaagttttca
    58921 atcatcaacc caccttcttg agcattaccg acttctttga catcgtcttt gtaatgtttc
    58981 aagctggtaa gtttaccatc aaaaataacg acactatcac ggataacacg aacattcgaa
    59041 tcacgtgtca ccttaccgtt gattaccata aagccaccaa ttgttcccac tttagaaact
    59101 ttgaaggttt cacgaataat ggcttcacca agaatttttt cttggtaaac agggtcaagt
    59161 ttccctttca tggcttcttc tacttcttca atgactttat agataatgct atgaagacga
    59221 atttccacat catccgtatc tgcttgttga cgagcttgtg gggtagggcg aacgttgaaa
    59281 ccgataataa cagcatttga tgcttcagca agggtcacat cagactcatt gatagcacct
    59341 acagcagagt gaacgacatt gacacggaca ccttccactt caatctttac aagagatgct
    59401 gcaagggctt caacagaacc ttgaacgtct gctttgatga tgacattaac agtcttgatt
    59461 tctcctgctt taagggtatc aaagagatta tcaaggctaa cacgctgtgt attttgacgt
    59521 tgtttgagga gggcacgttt tgatcgctcc tcaccagctg cacgcgcagc tttttcatca
    59581 gcgtaaacag caaagtgatc accagccatt ggtgtttcgt tcaaaccagt aatggaaact
    59641 ggtgttgatg gctccgcaga tttaacacga cgcccaaggt catttaccat ggcacggaca
    59701 cgaccaaagg tattaccaac aacgattggg tcttgaacat gaagagttcc ttgttggaca
    59761 agaagcgtag caatagcacc tttaccttta tctaagcgtg cttcaatcac agtaccaata
    59821 gcacgaaccg tcggatcagc tttcaattct tccacttcag caaccaaaag gactgtttct
    59881 aatagttcat caatattttt attaaattta gcagatatct ctacaaattc gcactctccg
    59941 ccccaagcag ttgagatgat accatattct gccaattctg cgataacacg ttctggatta
    60001 gcacctggtt tatcaatttt gttgatagca acaataattg gaacaccagc agcttttgag
    60061 tgattgatcg cttcaatcgt ttgtggcata acaccatcat cagctgcaac aatcaaaatg
    60121 gtgatatcgg taacggaagc tccacgtgcg cgcatacttg taaatgccgc gtgtccggga
    60181 gtatccaaga aggtaatttt cttgccagct tcttcaatct ggtaagcacc aatatgctga
    60241 gtaattcctc cagcttctcc tgttgccaca cgtgagttac gcaaagtatc aagcaaagtt
    60301 gtcttaccgt ggtctacgtg tcccatgata gttacaacag gtgcgcgttc tacaatattt
    60361 tcaggattga ggtaattttc atcctcaaag aagcgctcga tatcagcatc atctacttct
    60421 accttagcct tagcctcaat accataatct accatcaata attcgatagt atccccatct
    60481 aaagactggt tttgagttgc cataacaccc atcataaaca gctttttaac aatttcagcg
    60541 ggttcgcgtt tgatacgttt tgcgatttcg gcaactgtca tgccttcagt atattcaaat
    60601 tcttttggca attcatggaa tttacgctcg gttactggtt ttggagcggt gttggtattc
    60661 ttaacatttt tgcctttttt ggtcttttta tttttattcc agttactatt tttttgattt
    60721 ctcacttggt tttgactatt ccaactcttc ttatttttct tttgtccttc ttgtgaatga
    60781 tgagttaact cacgattctt ttcaggacgt gcttgttttt tacggcgatt atcagcagta
    60841 gatttagcac taatatttga tgactttaat ttagtttctg cttcttcaat agatttcagt
    60901 gctgcttcac gatggctcat ctcctcagct tgtgctttta gagccgcttc tttagcttct
    60961 tgtcttgcca actcagctaa acgcttagct tcttgctgtg cacgaaaacg tgtttcactt
    61021 tggcgtgagt attcagcatt ttgttcagct tttaaggcag cagcacgagc tttgaaatca
    61081 attttaggac ttttcgattg aggctcttgt cgtccttgct ttttttggtt tgtgaatcga
    61141 ccattcttgt gattctcctt agcaaaggaa cggttacgat caccaactag ctgatgatta
    61201 tcatgtctag gtgatacatt cgatgctttt cgctcaatac gcttatcgtt tgtatcacct
    61261 tgagaacgat gggtaatcct cttatctcct tgttcgttag tttgatgatt attgggctgg
    61321 cgataacctc ctcgacgttc ttgagaacga tgagaagagc catttgcttg ttttcgagca
    61381 gcctgttcct ttgcacgagc ctctctttca gctttaaaat tacgactctt tggcttagag
    61441 atctgtgttt tctctacatg ctcagaacct gtttctttga ccactgttac agagggttga
    61501 gcaacttctt tgggtttgac tgtttgagaa gctgtcacat caggtttaga agcctttgaa
    61561 aaacttgaaa taatcttttt cgcatccgct tcttcaacac ttgatgcatg gcttttcaca
    61621 tctaatccta agtatttagc gtgttcaacc acctctttac tacttttacc aatttccttg
    61681 gcaatttcat gtaatctttt ctttgacaat ttgtgtcctc ctattcatct attccataag
    61741 agtcctcatt ttctttgaaa atccagcatc tgcaacggca gcaaccttcc ttggtttacc
    61801 tagtgcagca cttaattcca gtgcattcaa cactgtggag acttctacat tataataatt
    61861 acttttatct gtcacttttt ttgtcacatt aggaccagca tcattggcta aaaatactaa
    61921 tattacctgc tggtgttgaa tagcttttac tactagttct tcacctgaaa tcacttttcc
    61981 agcccgttga gctagaccaa taagactaga taatctttct aaattagtca agacctaact
    62041 ctcttctttt gattttgtga tcaacataag caatcaagtc atcgtaaaaa ctttctggaa
    62101 tgtccattga gaaactcctg ttgaaaactt gttttttctt ggccattaag gcctcttgat
    62161 tgtctaattt gatataagca ccacgaccat tttgtttacc agttggatca atgaaaactt
    62221 gaccatcctt agtttttaca atcctaagaa gatctcgttt agcaataatt tcaccagaaa
    62281 caagtgattt tcgtaaaggt atttttttga ctttagacat caaacacctc ttttcttaca
    62341 cttcctcggc agtcataaca tcgtcaacaa ctggctcttc cacaactgtt gctgcttctt
    62401 tttccgcctc aagacgatca tattcgctag ctgatttgat atcaatacgg tagccagtca
    62461 aatgtgccgc taaacgaacg ttttggccgc gacgcccgat agctaatgat aatttgctat
    62521 caggaactac taccgtagca cgtttaagat cttcatcgtc aaaaagtacc atgtctactt
    62581 cagccggagc aatggcattg tagatgaact cagctggatc atctacccat tgaatcacgt
    62641 caatattttc ttcaactgga atttcaagcc ccgtcttagc atctacacgt tttggatgga
    62701 acttgctgat gaccttttta atattacttc caccacgtcc aacaattgtt ccgatggcat
    62761 caacgttagg attatgactg cgcacagcaa ccttggtacg gtcacctgct tcacgagaga
    62821 cactcatgat ttcaacagta ccatcaaaga cttcaggaat ttcttgctcc ataatacgtt
    62881 tgatgaattc tggatggcta cgactaacaa agacgttaac tcctttagga ttattttcaa
    62941 ctttgtagac ataaacgtca atacggtcat gtgatttgaa agtttcacct ggaatttggt
    63001 cttgatgaga caattgtgct tctagggaac caagattgac ataaataaaa cgttgatcaa
    63061 accgttcaac tgttcctgtc ataatttcac cttcatgctc tttgtattca ttgaacatca
    63121 cttcacgcat ttggcggcgc atcttttcca taatagtctg tttagctgat tgagctgcga
    63181 cacgtccaaa ttcattgaca gattcttcaa agcgaatctt atcacccaat tcataggcag
    63241 aactgatagc aagagcatct ttcaaactaa tctcaagccg gctgtcaaaa acttcttcaa
    63301 caacctcacg aaccgtaaat acttgaaaat cagctgtttt ttcattaaat tcaataacac
    63361 atgattctga ttgaccatag cgacgtttat aggcagactt taatgattct gtcactgcgt
    63421 caataatatc tgctttatca atgtgttttt cttcttccaa aatacggaag gcttctagca
    63481 tttctttgct cataatgtta tctaccttgc ttgtaaagct tggcaaaaat cctttcttaa
    63541 attaatacga tcaatagccc cctaaaggct cccttaattc cttttgttta gcttgtataa
    63601 actctatagg tgttgtttca aatttgctta agtgttccta aaaaagttta gtgctttgaa
    63661 ataaaagtta taatttgaca gccattctca ccttagcaac tgcttgatat ggtatattca
    63721 cgatcttatg acgtgtttta tcaagataat caatagtcaa cgtttcacca tcaaaggcta
    63781 ataagtctcc ttgaaaaact ttcaccttat caatagcttg ataaagactc acattgatat
    63841 aagagccaac tgctgctttt aaactgtcag ctgtcttaag cggacgctcc aaacctggac
    63901 tagagacttc tagcatatat tggtttggaa aaggatctgg atcaatcgta tctaacagcg
    63961 gactaataat attcgtcaag tcagatgtat cttccactgt gattccacct tccttatcga
    64021 ctaaaatact aaggatgtag tcactaccca ttttgtcata ctcaacgtct actaattcat
    64081 aaggtgcctt aatctcaggt gttactgtct tggttacgat atcgataata gatgtatttg
    64141 ctattttgat tacctcctct atttttatgc tcttctctaa gataattggt ccttgggaat
    64201 ccacttaata caaaagtggc gagacatatc ccaccacctt tctgtattat ttaagcctat
    64261 tataccataa tttaatagga atgcaaggat atgcactttg ttttactcaa aaggagagga
    64321 ggggattcga acccccgagc cccgttaagg actacacgct ttccaagcgt gcgcactaag
    64381 ccactatgcg acctctccat tactaaagga gttaatactg tatcaactcc tttatgttat
    64441 catattttga aacaaaatac tactagaaat ttgcctcaac tcggtaaatg acttgacctt
    64501 tattagagaa cttctcttca tattctgtca tgacatttcc ttcatagtta ctagcgtgta
    64561 agtcaagcca gatctgtctc aaggtcatgc cgtattgaga aaaactagct aaactgtact
    64621 caaacaagcc ccgattatcg gttttaaaat gaatttcacc gtgttctggc aagatacgct
    64681 tgtaagtgtc taagaaatcc ttgtaggtca aacgacgttt ttcatgcttg gtttttggcc
    64741 aaggatctga aaagttgagg tacatcatat ccacctcacc atcttcaaaa tagttggtta
    64801 aacttgatcc atccactcgc agaagtttga cattgggtac ttctgaagct aataccttat
    64861 ccaaggcgta gcttaggaca gataattgaa tatcaatgcc aatgtagtta atatcaggat
    64921 ttttcaaggc catccctgtg ataaatccgc cctttcctga accaacttcg atatgaatag
    64981 gacggtcatt tccaaaaacg tcatgccaac ggcccttggc atcttctgga tttaatatca
    65041 catagtgtgg gttattagct aagtgctcct cagcaccttt tcgttttcta actcgcatta
    65101 tttctttcta aatatttctc taaattttct gagggcataa atctcctgat tcacatgctc
    65161 catgtcacgc ttgtcaaaac acttgagaat ttgtgtcagg tgagaaaatt gaccatacca
    65221 aataattttt tgcataacct tgtcattatt tttatagcca taataagaca gccattctga
    65281 ccaacgagac cgtggaatat agtggctcaa caggtaagca acatcataca tccgatcagt
    65341 tagacgaaca gaatcccaat ctactaaaaa aatcatacca ctagtagtaa tcacccaatt
    65401 gctatgttta atatctccat gcacaatcgt tgctacttct gatttgaact ctggtaagct
    65461 ccgttttaat tctttaacga tagcttgtaa atatgaattt tgctgaattt gcaagggtgc
    65521 attttgctca aaatcaacca ataaatcgta tgggttttca atcttataat tgagctgaag
    65581 cagttgattg actaattttt tagatttgtg aaggcgcaat agaatatgaa tgatttgctt
    65641 actgttcata tcttctttgg tcaatgtacg gccgttaagc cattcttggg cactcatcat
    65701 atcaccattg cccatgcgtt tggcccaaag taactgtggc gcaatctgtt cttttgctaa
    65761 ggcaggtaga ataggggtcg tatttaattt tataaagaca cattccccat ttggataagt
    65821 gcctttataa gctttgccac ttttcccacg taagggagtc aaggtaagtt cttgttccgt
    65881 cgttgtcacc ttatcgccct ccttttctat cttttatagt cgtttacccc tattttactt
    65941 gttttaggct acttagtcaa tgatcttctt taacttataa ggtagatata tacaagctat
    66001 gaaaaccata cctacaatca aaatgagtgc ttttggcgct gatgagcaac acagcatatt
    66061 gacgattaac attaaaaagc ttaaacctcg taaaaaactt aacatatttt tcttcttgct
    66121 ccgactattt tcaggataaa gactagtcat ataatggtaa tcgtagtgat aataaagtga
    66181 aagtaattgg aatacaacta aatagttaaa aatgagtgct aaacttactg acaaataaag
    66241 attatggata aaaaatacag ataatgagct taatagcatt agtcgtaaaa ataagcccaa
    66301 ataatctgaa ctacgtaaaa aggctctagc ataaagggac agccaaaggt ttgaaggagt
    66361 ttgcttaact aattttaaaa gaggatttag ataagctctt tctttcactt ttgtagaaat
    66421 tcctttgact gttgtaaaaa gagagtaaaa ctttaaaata ctttgcttgc gattgctttc
    66481 aaatgcgaca gcttttgccc aatctaaacg atttcctctc aaaaaatatc ttgtctttcg
    66541 actaagcact actcttttta gtgccaataa tatcaaaact aagataataa aaataaataa
    66601 agacagacct agacgtctaa aaataggata taaaaagagc aatacagcag tctgcaaagt
    66661 tccccaaagc acaaaagaga gtcgctcagc ttgtttgata taagaaatca cttcttcttc
    66721 ttttggaagt aagaaatgct gatctgcctc ttctagatac gttgctatag atcccatact
    66781 gagcaataat gggatcaata tcccaagaca aacctgaata ggtagatgat tcgttggaaa
    66841 atggtttagt agctgaccat actgcaccat agcaaagcct aataaaaaca tcaacaccaa
    66901 aacaaagtga tcatttaaga cgtaacgaag gtatttgttt tgttgttttt gaaagtcttg
    66961 acggcgtttc agaaataatg ctttcatact taatcctctt ttgttaatgc aagatagata
    67021 tcatttaagc tcgctgaacg gtcaccaaaa gcttcttgca agtcagcaag agttccttgg
    67081 gcacgaactt gtccatgatg caaaatcaca aaacgatcac acattctttc agcagagtcc
    67141 aaaacatgtg tactcatcaa aatagatttt ccttttgctt tttcgacttc tagcgtttgg
    67201 attaagtctg aaatagctaa agggtctaac cctaagaatg gttcatcaag aataaataga
    67261 cttggatcaa tgacaaaggc acaaataatc atgacttttt gtttcatccc tttagaaaaa
    67321 ttgacaggaa accattcaag tttgtcagtt aaacgaaaca tttccaagaa aggttgtgct
    67381 cgtttttgtg ccacttctaa gtcgatatca taagccatag ctacggtgtt gatatgctct
    67441 gataaggtca attcttcata gagactagga gtttctggga taaaacctat tttttgacgg
    67501 taggcaactg cattttctgc tagagttaaa ccatcaatag aaatacttcc ttgataaggc
    67561 ttcaaaaagc caataatttc gttgatagtt gttgactttc cagcaccatt tagcccgatc
    67621 aaaccgacta actctccatt gtctacagaa aatgagacat cgtttaaaac agggatattg
    67681 tgatatcctc ctgttagatt tttaatgttt aacatataat ttctttctag tttttgatat
    67741 acttataata tattataaca aattcaagta gagaaggtga tataaaatgg aaaattgtat
    67801 tttttgcagc atcattcaag gggatatccc ctcttcgaaa gtctacgaag atgagcaggt
    67861 cctcgccttt ttagatatct cacaaactac aaaagggcat actctagtca ttcctaagca
    67921 acatgttcgt aacttactag agatgactgc tgagacagct agtcatctct ttgctcgtat
    67981 tcctaaaatt gctcgtgcta tccagtcagc tactggcgct actgccatga atatcattaa
    68041 caataacgaa gccttagcgg gacaaactgt tttccatgct catgttcatc tcgttcctcg
    68101 ttataatgaa gaagacggta tctcaattca atacaccact catgagcctg actttcctgt
    68161 cttggaaaag ctcgcccgac aaatcaatca ggaggttagt tcatgaaagt taaaaccatg
    68221 atagccgtcg gattattatc ttttaccgct tacaaaacat atcaaaaacg ttgtaccata
    68281 aaagagctat tatccatcag tcgacaagca aaggatgctg cacaacttga tttagataac
    68341 attaaagcaa accttgacct cattcacagt caaggaaaag taattcaaaa tattagtcag
    68401 gacttggccc ataaatggcg ctactttaac caagagacac aagcacacct cactgaaatc
    68461 caaaatcgta tggccaaata tcaaggagat agtgagctaa tttctagtga atcacctact
    68521 tgccaaaccg tcattttaac taacaaccat tccagatagt attatctccc tcatatactt
    68581 tatttgaaat cacagacagc tatcatcttt gatacctgtc ttttttatat tcaaaatcgg
    68641 atattttaaa cataaaaacc ctcagaacgt taggtctgag ggttgatatt agcaggagga
    68701 actaatgatc cagaccctga tgagctagac tcatcagctg ctaaagcatc tgatgaagaa
    68761 gacggcgtag ttggcgtatg gcttgaagca gtagagtcct ggtctgtact agcactctga
    68821 taagatgagc cggtatctac tccacttgaa taattagcgt aagagctata actatcagaa
    68881 taagatggag cctggcctga agagtcatag ttgttgttta ctgtctgaga cttagttgac
    68941 ccatacaaat tttcataaac agtagcattt gtttttaatt gactaacctt atgaagtcct
    69001 aattctgttc ggatacgatt ttggatttct aacaaatgat tagaggtaac aatttggtat
    69061 gatccaccat ctgataaagt ggcatcttct ccttttagtt gataagtctt aatagttcta
    69121 agtgcgtcac gataacctaa tagactaggg atagtgcgag aagagatttc gatattcgtt
    69181 tgcatattac tacttacagc agataaaatc ttccgataag agctaatgct atcaagagca
    69241 aggatttttt tcaatacctt ttgaatgact tcacgttgac gcttttgtcg accataatct
    69301 ccctcaggat catcataacg catacgagca taaaccaaag cttgttcacc gttaattttg
    69361 tgtgttccag gcgcaacagt agcttgatat tcaggttcgt tttcagcaat cgagatagga
    69421 aaatcaaact catttgtaac tgtaatccct ccaactgcat tcacaagatc aataaggcct
    69481 tgcatattaa tttgaacata gttatcaatg gtgatattca aaagatcttg cacggtcata
    69541 atagccatct gagcgccacc tgctgcataa gcagcgttaa gcttagcttc aacaccattc
    69601 atttcattat ttttgggtcc agataacgtg gttaaggtat ctcgttctaa actagtcata
    69661 gttgttttct tggtctttgg attaaccgta accaaaatca tcgaatcact gtttccttcc
    69721 cacttggagg cacgctctga agagcctgta tcaacaccca tcaacaagat agaaaaagct
    69781 cttgtttgtt taatggcatc acttttcttt gaagatgtcg aaaaatcttt aaaggtcttt
    69841 gataattctc ctgttgagaa ggtataagca ctagttagat agacacctaa tgccaagaca
    69901 gttgttaaca caatagctgt gaacattaaa actatttttt ttccaatttt catcgattca
    69961 cttactgact tacagattta cgcatatgat aaacatctaa gtcatctcca ttttttgatt
    70021 tgatgtcgtt ttttcgcata ctttcaatac gaaaaccata ctttttatac aggtaaatag
    70081 ccttagtatt tcttacttga acgtccaact taaggctttc gatataaggg ttttcttcag
    70141 cccaatcaag agcaatctct aacaataatt gaccgatacc ataaccacga taagtcttag
    70201 caactaacat aaatacatct gcttcagctt ggccttggga taatacttcc ccagaaagat
    70261 ttaaaagccc tactactttt tcatctaatc tagctagcag gcaaaaatca ataaaagagg
    70321 ttcgacttct tgataaaaag tctgacaatt cttgaggagt agcctctaat atagtctcta
    70381 cgcctgttat aaaatctgtt tctttggcag ctgccgtcac taaggaaagt acagcttttg
    70441 catcttgagg tacgccttct tcaataacga gactttgctg aatcatgtga cattatctcc
    70501 agaagctgac gagagcgctc accatgcgct aacaagtcta gttgacgacc tttgtctcgt
    70561 ttagtaatgg taatttgcaa atagtcttgt aataatccct ctcctaataa ttctccccac
    70621 tcaataacgg taacaccatt accaaaaaga aaatcatcta aatcaataga gtctggatca
    70681 tcaccaacac ggtaaatatc taagtgataa agaggtagac gtccttcata ttctctaaca
    70741 atagtataag ttgggctttt gatcatttga ctaatcccca tccctttagc aatacctttt
    70801 gccaatgttg ttttaccggc acctaagtcg ccagacaata caatcacatc tccaatagac
    70861 aaataagtac ctagggtttc gccgtaagct ttaagagtat attcattttc actataaaac
    70921 atagcaacat tatatcagaa aaaaaacata cttccaagca ctacctagaa gatgactcaa
    70981 ataaggtatt cgtaaagtaa aaacgcttct ttatattaaa ggttaaaatc aactaaagaa
    71041 gcggcagtta gtagcaaaat aagtaaatta tttggttata agatagttaa tatgatgaaa
    71101 tttacaatga acaagaaggt tgctccccaa ataatagggt gaatatcttt tgtttttccc
    71161 tcaacaactt ttactagaca atagaaaata aaggcagcgg caataccata ggaaatagag
    71221 taacacagcg ccataaagaa agctgcaaaa aaagctggaa gagcatctgc aaatttactc
    71281 caattaacat caagaaaaga agacaccatc atgacaccca caacgattaa agctggagcc
    71341 gtagcagcag ctgggacaat acctacaagc ggtaatagca atattgataa taagaagcat
    71401 actgcggtgg agactgctgt tagtccagta cgtccacctt cagcaattcc tgctgctgat
    71461 tcaacatagg tagtcgtatt tgaagttcca accaaagccc caatagaagt accgatagca
    71521 tctgcaaaaa gcgcacgatc catttttgaa ttaaaaccta tactattttc caaagcattc
    71581 tcatcgtctt gagagaaaat acctgttcga cgaccagttc cgataaaggt accaattgtg
    71641 tcaaaagtat ctgatagact aaaagcaaaa atagtcatga aaactagcgg taaacgactt
    71701 gaatcgctaa aaagagaact caaaccatcg aaagctgcaa ggaaagttgt acctaattca
    71761 gtccaagctt caccaatatg gctgatccca aaattgaggt tggacacatc cactattcct
    71821 aaaggaatac ctacaagagt tgttgcgaca ataccaatta aaatagcacc tctaaaattt
    71881 cgaatcacaa gagctgtcgt taaaagtaaa ccaaaaatag caagtaatac actggaatcc
    71941 gtaaaactag aaatcgtagg tacaactcca ccattggcgt ctacaaataa tagaccatct
    72001 gcaaatgttt tagccgatgc tttagccggt tcaacaccat ttaccattac tatattttca
    72061 gcagagatag aaaaagtaat gatatttgcg tttttaaatc ctaaataagc tacaaagaca
    72121 ccaattcccc caccaatagc atgctgtaaa ctaactggaa tcgccttgat gatactttta
    72181 cgaaacttgg ttacggtaat aaaaatattg aataatccac aaatgaaaac cattgccaag
    72241 gcttcttgcc atgaaaaccc taaagcaaaa acaactgtat aagtgaaaaa agcgttaagt
    72301 cccattcctg gtgccaacgc ataaggcaca ttggcaaata atcccataat taaggttgat
    72361 atggctgctg cgataatcgt agccaaaaag acagcattag agggcatccc cgctgcacct
    72421 aaaatacttg ggttaacaaa caaaatatag gacatggcaa aaaaggtcgt taaaccagcc
    72481 ataatctcag ttgagacagt tgtcccattt tcgcttaact taaaaaactt ttccattgaa
    72541 atggagtctc cttaattaaa tagtaggtaa aatcaaaaag cgcttatcac tagataagtc
    72601 tttttgacac ctcattatta ttgttattgt tcgtattaaa atgaacaata acactatgtt
    72661 accatttttt tgttcacttt tcaacgtcta taccttcatt tattcattaa aaaaaacagt
    72721 tatcctatct tttttactaa tgaatacgct taacttatct tttctcttta tcttggagca
    72781 aaatttgcta taatttaatt atgactaaaa aattgattgc cattgatttg gatggaacct
    72841 tattacatca tgacaacacc atctctacct atactcaaaa aaccatcaaa gctgtccaag
    72901 acaagggcca ccacgtcatt atttcaacag gccgtcctta ccgcatggca ctgggctact
    72961 atctgcagct caatttaaag accccaatca tcacttttaa tggggccttg acccacatgc
    73021 ctgaacaaaa atgggcctat gaacataatg tcactttgga caaaggctac ctactaaggt
    73081 tactaaaata tcaggatgat ttccagatgg attttattgc cagtgagtat cgaaaaaatg
    73141 tctacatcac catgaccaat ccagaaagta tcgacccgca actctttggt gttgatgaaa
    73201 ttactcagga catggcatta gagattacca aaatcactcg aaatccaaac gccttattga
    73261 tgcaaacgcg ccacgaagac aagtatgcct tagctaaaaa catgcgtgct ttcttcaaag
    73321 atgaaattga aattgattct tggggaggcc ctctcaacat tcttgaaatt tcgtctaaga
    73381 atgtcaataa agcttacgct ctgaactatc tccttggaat ttacaatatg gataaaaagg
    73441 atttaatcgc ctttggtgat gaacacaatg acactgagat gctagctttt gctggaactg
    73501 gttatgccat gaaaaatgct agccctgtgc tactgcctta tgctgatcag cagcttaatt
    73561 tttccaacga agaagacggt gttgccaaaa aattggaaga acttttcttg tagtagcaaa
    73621 cgaaaccact atttttcaga aaatggtggt ttttcttctg tcaacagcta tcaaaaaatg
    73681 aaaatcattt taataatttc aacatttttc agcatatttt tgttttaaac agcttgaaaa
    73741 cacctttaat atcaataatc tgcctattta atcctaaatt ctgaaaattt tttcatgttt
    73801 tgtactattt ttccgaaagg gcttgatttt ttagtgaaaa cgttttaaaa tagaaacgtt
    73861 cttgaatttc gtttaagtga aaaagaattg ccaaaattta gttttggaag gagattattc
    73921 ttcttcattt caacgaaaaa tattttaaag gaggaagaac aagaatgggt atcggtatta
    73981 ttattgccag ccatggtaaa tttgctgaag gtattcatca atctggttct atgatttttg
    74041 gtgaacaaga gaaagttcaa gttgttactt tcatgccaaa cgaaggacca gatgatttgt
    74101 atggacactt caacaatgct atccaacaat ttgatgctga tgatgaaatc cttgtgctag
    74161 ctgacctttg gagtggttct ccatttaacc aagctagtcg tgtggcaggt gaaaatcctg
    74221 accgcaaaat ggcgatcatc actggtctca acttgcctat gcttattcaa gcttacactg
    74281 aacgtcttat ggatgctggt gcaggtgttg aacaagttgc tgcaaacatc attaaggaat
    74341 ctaaggacgg tatcaaagcc cttcctgaag accttaaccc agttgaagaa actgctgcaa
    74401 ctgaaaaagt tgttaacgca cttcaaggag ctattcctgc tggaactgtc atcggagatg
    74461 gtaaattaaa gatcaatctt gctcgtgttg acactcgtct tttacacggt caagttgcaa
    74521 cagcatggac tccagcttct aaggctgacc gtatcattgt tgcttctgat gaggttgctc
    74581 aagatgacct tcgcaaacaa ttgatcaaac aggctgcacc tggcggtgtc aaagctaacg
    74641 ttgttccaat tagcaaattg attgaagctt ctaaagatcc tcgttttggt aacacacacg
    74701 cacttattct tttccaaacc cctcaagatg cccttcgcgc ggttgaaggt ggtgttgaaa
    74761 tcaacgaatt gaacgttggt tcaatggctc actcaactgg taaaacaatg gttaacaacg
    74821 ttttatcaat ggacaaagaa gacgttgcta cttttgaaaa attacgcgac ctaggtgtta
    74881 cattcgacgt ccgtaaagtt cctaacgatt ctaagaaaaa cttatttgag cttatccaaa
    74941 aagctaacat taaataagtt tcaaacgcta taaggtttta aaacgatgac tagctaactt
    75001 attagcaaaa agtcctcgtt tactatactt tgaaaggatt acaacatgtc agatatttcg
    75061 attatttctg caattttggt cgttatcatt gccttcttcg ctggtcttga aggtatcctc
    75121 gaccaatttc aaatgcacca accacttgtt gcctgtactt tgattggact tgtaactgga
    75181 caccttgaag ctggtgtcat ccttggtggt acacttcaaa tgcttgctct tggttgggca
    75241 aacatcggtg ctgccgttgc ccctgatgct gcccttgcct ctgttgcagc tgctatcatc
    75301 atggtcaaaa gtggcgactt tactcaaaaa ggaattacct ttgcttactc aacagctatc
    75361 ccacttgctg ttgctggtct tttccttaca atgatcgttc gtactttgtc aactgccctt
    75421 gtacacgctg gtgacaaagc tgccgctgaa ggtaatttcg caggtattga acgcttccac
    75481 tttattgccc ttcttcttca aggattgcgt atcgctgtcc cagcagctct tcttgttgct
    75541 gttcctactt cagccgtaca atctgttttg aatgctatgc caaactggtt gaacgaaggt
    75601 atgcaaatcg gtggtgcgat ggttgttgct gtaggttatg ctatggttat caacatgatg
    75661 gctactcgtg aagtatggcc attcttcgcc ctaggttttg ctcttgcagc tatcagccaa
    75721 ttaaccctta tcgctatggg tattatcggt gtagcaattg ccttcatcta ccttaatctt
    75781 tctaaaaaag gtggtaacgg tggtaatgca gcaggttcag ctgatccaat cggcgacatc
    75841 ttagaagact actagaaagg ggtaagaaca aatgactgaa caaattaaat taactaaatc
    75901 agaccgtcaa cgtgtttggt ggcgttcaca attcttacaa ggttcttgga actacgaacg
    75961 tatgcaaaac atgggctggg cttatgcact tatccctgct cttaaaaaat tgtatacgtc
    76021 tcctgaagac cgtgcagctg ctcttgagcg ccacatggaa ttctttaaca ctcacccata
    76081 cgttgcagct ccaatcattg gtgtaacact tgcccttgaa gaagaacgcg caaatggtac
    76141 gccaattgat gacaaggcta tccaaggggt taaaatcggt atgatgggac ctcttgctgg
    76201 tatcggtgac ccagtattct ggtttacggt tcgtcctatc cttggggcac ttggtgcttc
    76261 tttggcttca acaggtaaca tcgttggtcc acttctgttc ttctttggat ggaaccttat
    76321 ccgtatggcc ttcttatggt atactcaaga atttggttac aaagctggtt ctgaaattac
    76381 taaagacatg tcaggcggta tcctccaaga cattactaaa ggtgcttcaa tccttggaat
    76441 gtttatcctt gcagtgcttg ttcaacgttg ggtatctatc aactttacta tcgaccttcc
    76501 tggaaaacaa ttgtcagatg gtgcctatgt ggtcttccca gatggcgctg ttaaaggtgc
    76561 tgagttgaaa actatccttg ccaacgctat tggcggtatg agccttgata aagtccaagc
    76621 tcaaaccctt caaggacaat tggactctct tatcccaggt ttagctggat tactccttac
    76681 attcctttgc atgtggttat tgaagaaaaa agtttctcca atcgcaatca tcatcggctt
    76741 gtttgcattt ggtatccttg ctcaccttgc aggtattatg taatcaacca atggaagtct
    76801 gagatgaact caggcttctt ttttatgctt tatgtcagga aaatcccact taaaatatgg
    76861 tataataact acaactacgc aatgaaagga actaaaatgg ctcaatcttt aaacactagt
    76921 gtcgaataca agacaaaagc tgtctcctac cttggaatgg gaggcaaagt tggtcatatc
    76981 ttactcggtg acaaggccct tgaattttac aacgataaaa atgtgaatga ttatattcaa
    77041 attccttgga cagccatcaa tcacatcggg gctaatgttt caagaaaaaa agttagccgc
    77101 cactttgaaa tttttacgga ccaaggcaag tttttatttg cttctggaga ctctggaaaa
    77161 atcttaaaaa tcactcgtca acatattggt aatgagaaag tgattacatt accaaccttg
    77221 atgcaaacct ttattaacaa attttttcga cattaaaaaa ataatgagca gtgccgattt
    77281 atcatttcaa gaaaacaaag aatagtagct ctaaattgct atttagtgga aaagattccc
    77341 tcatttgagt ttactttttc ttgttttttt gttataatag ttctaacgga taagtaatac
    77401 ctttttttca ttcagagagt ctgtggatgc tgtgaacaga tagggaaaat gatatgaaat
    77461 tctaccgtgt tatcaataaa atagagatta agtgcacaga ttgtgaagct ggatggaacc
    77521 gcgccaaagc gctccagcat cttcataagc tgtgcttttt ctatcgtcag agaatcacaa
    77581 gatccaactg tcttacttag ccttggttca ctgacagcta ctaataacta tcttaaagga
    77641 gcttctgtat gctagatctt aaacgtatcc gtaccgattt tgacactgtc gctgctaaat
    77701 taaaaaaccg tggtgtttct gaagacaccc tgacccatct taaagaactt gatgaaaaac
    77761 gtcgtactct attagtgcaa tcagaagaat taaaagcaga gcgtaatatt gcttctgcag
    77821 ccatcgccca agcaaaacgc caaaaagaag atgctagtca acagattgct gatatgcaaa
    77881 aagtctctgc agatatcaaa actattgaca atcaactagt agctatcgac cagcaagtta
    77941 ctgacatcat cactgtttta cctaatactc ctcacgattc tgtctctgtt ggagctgacg
    78001 aagaagacaa cgtcgaaatt cgccgttggg gaacgcctcg tgactttgac ttcgaagtta
    78061 aggctcattg ggatctaggc gaagatcttg atattttaga ctgggaacgt ggggcaaagg
    78121 taactggtgc tcgtttctta ttctataaaa atcttggtgc tcgtttggag cgtgctcttt
    78181 ataacttcat gctggatgaa catatcaaag aaggttatca agaaatcatc acaccttaca
    78241 tggttaacca cgattccatg tttggtacag gacaatatcc aaagttcaaa gaggacacct
    78301 ttgaattagc agataccaac tttgtcctga ttccaactgc tgaagtgcct ttgaccaatt
    78361 attaccgtgg ggaaatccta gacggcaaag aattgccaat ttactttact gcaatgagcc
    78421 catcttttcg ttctgaagcg ggttctgcgg gtcgtgacac acgtggcctt atccgcctac
    78481 accaattcca caaagttgaa atggttaaat ttgctaaacc agaagaatct taccaagaac
    78541 tagaaaaaat gactgctaat gctgaaaata ttcttcaaaa acttggtttg ccatatcgcg
    78601 tcatttccct ttgtactgga gacatgggct tctcagctgc taaaacctat gaccttgaag
    78661 tctggattcc tgcacaaaac acctaccgtg aaatttcatc atgttcaaat actgaagatt
    78721 tccaagcacg acgtgctcaa atccgttacc gtgatgaagc tgacagtaag gtcaaacttc
    78781 ttcacaccct taatgggtca ggacttgctg tcggtcgtac cgtagcagcc attttagaaa
    78841 actaccaaaa tgaagatggt tctgttacca tccctgaagt actccgccct tacatgggtg
    78901 gcgaaaccgt catttcacct aaataataaa ctcaccccag agatcattaa agtgatttct
    78961 ggggtttact attttaaaga gccaccacat cacttgaaac tcactacatt gcccctttaa
    79021 caacactttt tttcacacta gtttatcaaa agtcttatta gtatacccat ttccttattt
    79081 acaagactag ttaaaaatcc ttttggaaag gcctccctta gcttgataaa cacgtaggga
    79141 gactccaaaa ggatgttgtt aatatttacg aaagcgttgg taacgctcat ctaataattg
    79201 gtctaatggc ttagcttgca aactggttat ttgttcgatg aggttagctt tgatgatgtc
    79261 aacgatttca cttgaaaaat aaccatgttc tggaataata cggtctacta tgcccatttg
    79321 atacaattcg cctgcggtaa ttttcatcaa ttcagcagcc tctgtcgctc ttgaaccatc
    79381 tttccataaa atagaagcaa agccttctgg actaaggact gcatacatgg tgttttctag
    79441 catccagacc tgatcggcaa ccgccaaggc taatgcacca ccagagcctc cttcaccaat
    79501 aatgatggcg ataatgggaa ccttgagatc actcatttcc atcaaatttt tagcaatggc
    79561 ctcaccctgt cctcgttctt ccgcaccgac acctggatag gctcctgcag tattgataaa
    79621 ggtcacaact ggtcgtccaa atttttctgc ctgtttcata aggcgcaaag ctttacgata
    79681 accttctgga ttgggctggc caaaattcct tgccaaatta tcctgtaaat tcctaccttt
    79741 ttgaatacca atgaccgtaa caggttgtcc cgccaaataa gctaagccac ctacaatagc
    79801 accatcatct gaaaaatggc gatcgccatg cagttccata aagtcatcga aaataaggtt
    79861 ggcgtaatcc aaagttgtta aacgcccttg atcacgcgct tcttttaaaa ctcttgatac
    79921 atctgtcatt ggccacctcc atgaaatgct actaagtggg caatcttgtc tcgcaactct
    79981 gttcgtttca caatagcatc cacaaaacca tggtcttgta aaaattctgc tttttgaaaa
    80041 tcatccggca aattctcacg tactgtggtt tcaataacac ggcgtccagc aaatccaacc
    80101 aaggattgag gttctgctaa aataatatcc ccttccatgg caaaactagc tgttacccca
    80161 ccagtagttg gatctgtcaa aatagtgagg taaaagaggc ctgcattaga atgtcttttc
    80221 acagctgcag agaccttggc catttgcata agactcatga tcccctcttg catacgggcg
    80281 cctcctgaag ccgtaaaaat caccaccggc aggttttctt cgatagccaa ttcaaacaat
    80341 cgggtaattt tttccccaac aacagttccc atactagcca taataaagtg agaatccata
    80401 atagcaagag caatttgttg tcctttaacc atagctttcc ctgtcaaaac agcttcatgc
    80461 agaccagttg tttccttggc tttttgtaat ttttcctgat aacctggaaa acgtaacgga
    80521 tccttggttt caatacttgt aaataattcc tggaaagagc cttcgtcaac tgttaaggtc
    80581 agccgctctt gggcagaaat cctaaaattg taagaacagg ttgggcaaat ctttgccaat
    80641 cccaaatctt tcttataaat catgtgctta caagctgggc atttcgcaaa gagttcatct
    80701 ggaacttctg ggacattatg gctgacagat cctttgaggg aattattggg agtaatacgg
    80761 atgtatttat cttttttacg aaataaagcc atattttctc ctaatcttta ttgtaatgtg
    80821 gcaggaacgt ttccatcaag aaagaggtat cataatctcc tgcaatcact cgcttatctg
    80881 aaatcaaatc gagctggaag tctgtattgg tgataatgcc ttcaatttcc aattcaacta
    80941 aggcacgttg cattttcatc aaagcgtcaa atcgattgct tccatgaacg atgattttag
    81001 caatcatgct gtcataataa ggaggaatgg catagccatt gtaaactgct gaatcaactc
    81061 gtagtcctac accaccactt ggcatataca agtctgtaat ctttcctgga ctcggtgcaa
    81121 agttaaaagc agtattttca gcattgatac gacattcaat agcatgtccc gtgatagtga
    81181 tgtcttcttg attaatcgcc aaaggctgac ctgctgcaat tttgatttgc tctttgacaa
    81241 tatccactcc tgtcacaaat tcggtgacag gatgctcaac ttggatacgg gtattcattt
    81301 ccatgaaata gaatttctcg ctgtcttcgt ccaacaaaaa ctcaatggtt cccgcatttt
    81361 cataggctac agcttcagct gctctaaccg ctgcttgccc catttcgtgt ctgagggtat
    81421 tgccaatagc aatggatgga ctttcttcca agactttttg attattccgt tgcaaggagc
    81481 aatcccgttc tcccaagtga atgatgttac cgtgagcgtc tcctaaaatt tgcacctcaa
    81541 tatgtctagc tgggtaaatt actttttcca aatacatggc gccatttccg aaagctccca
    81601 aagcttcttg actggcagca ttgaaagccg cctccaaatc tgcttctgtc tccactttac
    81661 gaatcccttt acctccacca cctgccgatg cttttagcat gacaggataa ccaatcttat
    81721 tggcaatagc taaggcttct tgagcgttat aaacttcacc atctgaccct ggaataacgg
    81781 gcactcctgc cttaatcatt tcagaacgag cattgatttt atcacccatt ttatccataa
    81841 ccgatgcgga tggaccgata aatttaatat tcatctcttc acacatggtc gcaaactttg
    81901 agttttcact taaaaagcca aaccctgggt gaatcgcttg ggctcctgtc acaatagctg
    81961 ctgacaagac ggaattcata ttaagatagg attccttgga acgggcagga ccaatacaga
    82021 tagcctcatc cgccaatatc gtgtgcagag cttccttatc cgcttccgaa taaactgcaa
    82081 ctgtggaaat ccctaattct cgtgcagcac gaatgatacg cactgcaatt tcaccacgat
    82141 tagcaattaa gattttttta aacataaggg tttcttcctc cgcagaacaa tcattctcat
    82201 tgcccacagg caaaggttaa tgttccactt gctgctagct tgccatcaac ttctgccctg
    82261 gcttcaacga cagcaatggt accgcgacgc ttgataaagg ttgctgtcat cacaagttga
    82321 tcaccaggga cgacttgttt tttgaacttc actttatcca ttccagcgta aaagaccaac
    82381 ttgcctttat tttcttcttt tgacaattct aagacaccag ctgtttgagc caaagcttcc
    82441 ataatcagaa cacctggcat cacaggatag tgaggaaaat gcccgttaaa gaaaggttca
    82501 ttaatagtca catttttaat ggcaacgata tggtcgtctg acacttctaa tacacgatca
    82561 accaataaca ttgggtagcg atgaggcaaa gccgcttgaa tttctctaat atccatcatt
    82621 tgatccgcac caatccttgt ccaaattcaa tgacatcttc atttgatacc aaaatttctg
    82681 taatcacacc atcacatggc gctggcactt cgttcatcac cttcatggct tcgataatca
    82741 caagggtttg tccttttttt acagtatctc cgactgccac aaatggtggc ttgtcagggc
    82801 tagctgcaag ataggctaca ccgactaaag gactttcaac aatatcacct tctgctacaa
    82861 aagattctgc ttgtggttgc tcctctacag gaacatcctt aactgatgct ggactagacg
    82921 cttccgaagc agttggattc ggaacaagtt gtacctgtgg tacaggcaca gcatgttctt
    82981 gatttgatgt cgatgcattg aggtgttgtt cgtttttact aaagattagc tcaccttcat
    83041 ttgttttgaa taaaaattca cgtaggcttg aggtatcaaa ctgagccatc aaatctttga
    83101 tttcttgaat attcaaccta ctcctcccaa catttgaaag ctaatacagc attatgacca
    83161 ccaaatccaa aagtatttga aatggcatag ttgatagctg tttcttttcc ttctccaaag
    83221 atgacatttg cttcgatatc ctctgataaa gcttgtgtcc cagccgtcat cggaacatag
    83281 ttatgacgca tagcctcgat agtggcaata gcttcaatag cgcctgctgc tccaagaagg
    83341 tgacccgtaa acgattttgt tgaagacacc ggaacatcct taccaagaac ggctacaatt
    83401 gcttgacttt ctcctttttc attagctggg gttgaagttc cgtgcgcatt gacataatta
    83461 atagcactgg cttcaatacc agcttcttgt aaggctaagt ggatggcttt acgagctcct
    83521 aatccctcag gatttggaga tgtcatatgg taggcatcgc aggtatttcc ataacccaca
    83581 atttctgcta agattgtcgc cccgcgttct tgcgcatgtt ctaggctttc taaaacaagc
    83641 attcctgatc cttctcccat gataaaacca ttgcggtctt tatcaaatgg aatagagctt
    83701 ctgcttggat cttcagttgt tgagagagct gttaaacttt ggaagccagc aatggcaaac
    83761 ttggttatgg ccgcctctga cccaccaact atcatcacat cttgagtccc aaatttaatg
    83821 gcacgaaagg catccccaat cgcatcattt gaagaagcgc aggcagtatt aattgattta
    83881 catactcctt gagcttttaa agacatggcg acatttcctg cagccatatt tggtagcgct
    83941 tttggcaacg tcattggctt cacacgtttt ggcccttttt catgtaagcg aatcacttgc
    84001 tcttcaatct ccgcaattcc accaatacct gaagcaacaa taacgccaaa tcgatcggaa
    84061 tcaatcatct caatatttaa atcagcatga ttaatagcct ctttcgctgc gtaaagagca
    84121 taaagagaat atctatcgaa acggttcaaa tcttttttca caaagtattt gtcaaatgga
    84181 aaatcctgaa tttcagcagc attcttgact gcataatcag tcgtgtcaaa tttagtaata
    84241 ggaccaatac caatttggcc agctttcaga ttgttccaaa acgtttcagg atcatgcccg
    84301 attggagatg ttagaccata acctgttacc actactcttt taaatgtcat ttcactacgt
    84361 ctccttattg cattgtcata ccgccatcaa tagcgataac ttgtcccgta atataatctt
    84421 gttccaccaa gaagcttgct aagtgagcaa cttcttgagc ttttccaata cgttttattg
    84481 ggatttgact taagatttgc tcttgcattt tttcaggaag gacacctgtc atgtcggact
    84541 cgataaatcc tggagcaata gcattcacgc aaatgttacg agcagcaact tcacgggcaa
    84601 cagacttggt aaaaccaatc attcctgcct tagaagcggc atagtttgct tgcccaatat
    84661 tgcctgttaa accaaccaca ctagagacat taataattgc tccttggcgg gccttgatca
    84721 ttggttttaa cactgattga gtcatgttaa aagcaccggt caaattgatt ttcaagacgc
    84781 gctcaaaatc ctcttccgtc attttaagca tcaatttatc attagtaatg ccagcattgt
    84841 taactaaaac atcaatcgaa cctaaacttt cgatagcttc attgaccata cgtttagctt
    84901 ctgatgcttc tgaaacatcc ccagagatgg taacaactgt aacgccgtag tcagtaaaac
    84961 tagcaacaag ctcctcagag atagcagagc gaccatttaa gacaatatta gctcctaaac
    85021 tggcgaattg atgagccatt gctaaaccga tacctctcgt tgagcctgtg ataaatatat
    85081 tttttccttt aatttccatg aatgtcctct ctatctaaaa ataaacgtaa gcttaccatg
    85141 ttttcaacac tattacatag taaattttta tcaattttct tcacaaaacc tgtcaaaacc
    85201 ttacctggtc ctacctcaat gaattgtgtt atgccacttt ctactaaagt cgcaacactg
    85261 tcataaaaac gaacaggctc catgacttga cgggctaata gttctgggat acggtctttt
    85321 tccataatat tagcttcggt attaccaacc aaaggaatct tgaagtcact gaagttgtat
    85381 ctttctaact ctttagccaa caagcggcta gctggttcta acaaagcagt gtggaaagga
    85441 cctgacacgt ttaaagggat taaacgctta actccccttt cctttaaaag ttcaactgcc
    85501 acgttcacag catctgtctg accaccaatt acaatttgac taggagtatt atagtttgct
    85561 ggagcaacca ctccatgttt agcagctatt tgacagactt cttcgatgac ttgcacgtct
    85621 gtattcataa cggcaaccat ctttccagat ccttgtggtg ctgcttcctc catcaagcgc
    85681 cctctcttag ctactaagga tagagtatct tcaaaagaga gtgcccctga tgctaccaaa
    85741 gctgagtatt ctcctaagga aagaccagct accatatccg gtgtaacgtg atgtaagccc
    85801 aaaacacggt aaatagcaat tgatgatgtc aaaatagctg gttgcgtata gctagtttga
    85861 ttaagtttta actcgtcact atcaatcaaa cggcgcaaat cgtatcccaa tacttgacta
    85921 gcttgatcaa aggtttttct tacaatagca aagttatcat aaaaatccct tgccatccct
    85981 aatttttggg caccttgacc ggcaaataaa aaggctgtct ttgtcattat cattatcctt
    86041 catgtgttta tctacttttc tattgaaaca gattgccagc gcttagcttc attttgaata
    86101 acacgagctg caccataata aatatctttt aaaatcgttt cacagctttc ttcttttctc
    86161 acaagccctg caatttggcc agccataaca gatccattga ccacatcgcc ttcaataaca
    86221 gcatgtcgaa gcgatcctgc tcccatttct tcaatatcag tagctgtttt ttgaccaatt
    86281 aaaaatgctt tttctgcttt tgcgtaagct gaggtcaatt tatttttaat agaacggaca
    86341 gggtggccca caacctgcgc agaaatcacc gtatcaatat cttttgctgc taagatttta
    86401 tctttaaaat tttggtgggc attggattct ttagcaacaa caaagcgagt tccaatttga
    86461 acagcctctg ctcctaacat aaatgctgct gctgcaccat gaccatcagc tataccacct
    86521 gccgcaatga caggaatcga aaccgcttca acaacttgtc ttactaaaga catagtcgtt
    86581 aacttgccaa tatgtcctcc agcttccata ccctcagcaa tcactgcatc taccccaagc
    86641 ttttccatac gtttggctag cgcaacgctt gggacaacag gaacaacgat tatacccgcc
    86701 tggtgcagtc tttccatata ctttcctgga tttcctgcgc ctgttgttac tactttaaca
    86761 ccttcttcaa tgaccagatc aacgatatca tcagcaaaag gagataaaag catgatatta
    86821 accccaaaag gtctatcagt aatagcttta acacggtcaa tgttggcttt aacaacttct
    86881 tttggagcat ttcccccacc gatgatacct agcccaccag cattggacac tgctcctgct
    86941 aaatcaccat ccgcgaccca ggccatacct ccttgaaaaa tgggataatc aatattaagt
    87001 aattctgtaa tacgtgtttt cataataact ttctataaaa aataaggaga ataatttgat
    87061 aatcaaacta ttatagtaag aagaaagagc gagctagatc ctaaaaagag tctaatccca
    87121 ccctaatggt ttgattaata cttattgttt ttttagtgat gaacatgaac ataacagcag
    87181 taagctttgc atagacttct gatgttactt gtcactttta tccttatttt gacttttcct
    87241 caacgtaagc aacaaggtca ccaacagtat ttaatccttc ttctgtttca atttgaatat
    87301 caaaagcatc ttcaatttct gaaataactt ggaaaacatc aagtgaatct gcatctaaat
    87361 catcaaatgt agtttctagt gttacttctt ctgtctcctt accaagttct tcaacaataa
    87421 tttcttgtac tttttcaaat actgccatgt ttatttctcc ttaaaaaata taaatttgtt
    87481 tttataaatg tgctaggcac atgaataact agattttaac aattagactt ccccatgtca
    87541 aacctccacc aaaaccggaa agtaagattt tttgggtacc atctaaccta atctgtccct
    87601 tttgaacagc ctctgacaag aggattggga tactagcagc actagtatta ccataacgca
    87661 tcatgttttc aaggaatttt tcccgaggaa catcaatctt gcgtgctatt ttatcaagta
    87721 tacgacgatt agcttgatgc aataaacaat agtctatatc atcttttgta atatctgatt
    87781 gcgccattag tgtgaggatg ctttttgaca catccctaat cgcaaaatca aatatggcac
    87841 gtccatccat ctgaatagtc gctatggctt ttttgccaat tgagtaaggg gaggaaaggc
    87901 tagtttctcc tgaaattaaa ctctgacatc tcgcaccatc tgtgtgtaat gtttccgcta
    87961 aaacatgttt atctttactg gcttccagta gcacgccacc agctccgtct ccaaaaagaa
    88021 cggctgtcgc tcgatcctgc caatttacta acttagataa agtctctgca cctattacca
    88081 ttccgttttg gtaggcacct gatgcaataa gcttatctgc catagccaag gcaaagacaa
    88141 agccactaca agcagcagtc atatcaaaag caaaagcact tgtagccgca atagctgctt
    88201 gaactttcgc agctgttgat ggcatagtgg catcagggct gatagttgca acaataataa
    88261 aatcaatagc atcagctttt aacccagact gagtcaaaag ctgatcagca acctgaatag
    88321 ctaggtcact agtcatttca tctctagaaa tatggcgttc tgctattcct gttcgagaaa
    88381 agatccactc atgactagtg tccattatgc tagctaaatc attattagtc actaactgct
    88441 gtggaacata gtgggctacc tgactgattt tagaaaaaat catttaaacc aaatcctcca
    88501 aaaattgatg tagattccct agtccacgca ccaatgcctg catctcttca tcactcatat
    88561 cagcaatgac atgtccaacc atatttttat ggaactttgc atggaggcgg tccaaaagtc
    88621 gacccctttt tgttaatgac aggtaaacaa ctcgcctatc tgagcgtgat cgcgttcttg
    88681 cgatataacc ttttgcttct aatttattta agctagtggt tactgtccct aacgttacca
    88741 ttaattctct ggcgatatca cttggagtca cctgatcata tttgccgata atttcaatag
    88801 tgtgcatctc ttttaaagag acatcactaa actgactcgt ctttaagctc atttcttcaa
    88861 taaccaaaat ccggttgaaa atatcaacta agtattggtt aattttgtca tattccaagt
    88921 aaacacctcc tagcaataaa ctttgacaat caaagtatat caaaggtcaa agtattttgc
    88981 aagcaatagc tgtcttactt cccttggaaa tttggtcgtc gtctttcacc ataagctctg
    89041 acaccttctt tgaaatcctc tttgaaggct agctcctctt gaatagcaag ctctgcctta
    89101 gcataatctt cccatcctgt gaaaaagctt tgccagacca atgatttcat tccagcataa
    89161 gaatttgaag agccacgtct caatcgcttt aaaagttgaa gacaaacttt gtctagttta
    89221 tcagattctg ccgtacggta gacaaaccca taatcgatcc ctttatcagc agtaattcct
    89281 tcacctgtca tcacaaggtg agttgcacga ttaagtccta ctgcacgagt caatagaaat
    89341 aaaccaccgg catccggtgc tagtccaaca tttacaaaag cttggataaa ttttgtttga
    89401 gtactagcga tacaaaagtc aacagctaaa gctatattaa aagccgctcc agctacagct
    89461 ccatcggcgc aaaggatgac tggttttggc aaatgcttga ttgcaaaaga aatttcttgt
    89521 accagttcag caatcttgac tagcgactgc acattatctt ttgcaacagc ttcttgcatt
    89581 tcaactaggt caccaccaac tgaaaacact tttccaacgg ctttaattaa taaaaaacgc
    89641 acagatgtat cgcgtttaac ttctgctaat gctaccagaa tctcttgaca aattggaata
    89701 ttaaaaccgt ttgaaacctc tggacggttt aaagtcaatg tcgcaagatc atctacaaca
    89761 tcaaagatga tgtgtttaaa
//
LOCUS       DAUGSW010000005        82651 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUGSW010000005 DAUGSW010000000
VERSION     DAUGSW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82651
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.005"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            265..1824
                     /locus_tag="VIB18_000385"
     CDS             265..1824
                     /locus_tag="VIB18_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEQ8765418.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMGNVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            1921..4119
                     /gene="nrdD"
                     /locus_tag="VIB18_000386"
     CDS             1921..4119
                     /gene="nrdD"
                     /locus_tag="VIB18_000386"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEQ8765419.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            4301..4447
                     /locus_tag="VIB18_000387"
     CDS             4301..4447
                     /locus_tag="VIB18_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765420.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSTKKADKKSRVQELKARFLEKSK
                     KQDN"
     gene            4476..5411
                     /locus_tag="VIB18_000388"
     CDS             4476..5411
                     /locus_tag="VIB18_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8765421.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTNLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENKTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIAASQLSYGELKVELPKD"
     gene            5420..5929
                     /locus_tag="VIB18_000389"
     CDS             5420..5929
                     /locus_tag="VIB18_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8765422.1"
                     /translation="MEIRRPTLEDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLASQGVPAIQYVAFDEKNQALGFLNLRLRLNASLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSCAISKNITTILVTCDETNVASRAVIVANGGILEDSRGGTERY
                     WIEEQRGDK"
     gene            5929..6543
                     /gene="nrdG"
                     /locus_tag="VIB18_000390"
     CDS             5929..6543
                     /gene="nrdG"
                     /locus_tag="VIB18_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEQ8765423.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(6717..7448)
                     /gene="yaaA"
                     /locus_tag="VIB18_000391"
     CDS             complement(6717..7448)
                     /gene="yaaA"
                     /locus_tag="VIB18_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEQ8765424.1"
                     /translation="MLTFLIPTAKEMMIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(7490..8347)
                     /locus_tag="VIB18_000392"
     CDS             complement(7490..8347)
                     /locus_tag="VIB18_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8765425.1"
                     /translation="MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLVLNYFLTRGISLEGAAD
                     HGHSEAIYLSDPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKH
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLTFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     RVNVILGQD"
     gene            8554..8864
                     /locus_tag="VIB18_000393"
                     /pseudo
     CDS             8554..8864
                     /locus_tag="VIB18_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(9143..9856)
                     /gene="treR"
                     /locus_tag="VIB18_000394"
     CDS             complement(9143..9856)
                     /gene="treR"
                     /locus_tag="VIB18_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEQ8765426.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIITREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            10067..12091
                     /gene="treP"
                     /locus_tag="VIB18_000395"
     CDS             10067..12091
                     /gene="treP"
                     /locus_tag="VIB18_000395"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEQ8765427.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     KIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANAIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSD
                     APVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDVFTVTVEGSLPRQIKVNDKLAVAVKK"
     gene            12158..13786
                     /gene="treC"
                     /locus_tag="VIB18_000396"
     CDS             12158..13786
                     /gene="treC"
                     /locus_tag="VIB18_000396"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEQ8765428.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFENLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMGQGNGWNALFYNNHDQPRALNRFIDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYADEAELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILAEN"
     gene            13994..15889
                     /gene="pepO"
                     /locus_tag="VIB18_000397"
     CDS             13994..15889
                     /gene="pepO"
                     /locus_tag="VIB18_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEQ8765429.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGDHVPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYMWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(16055..17095)
                     /locus_tag="VIB18_000398"
     CDS             complement(16055..17095)
                     /locus_tag="VIB18_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEQ8765430.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(17229..17996)
                     /gene="rpsB"
                     /locus_tag="VIB18_000399"
     CDS             complement(17229..17996)
                     /gene="rpsB"
                     /locus_tag="VIB18_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEQ8765431.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            18300..21374
                     /locus_tag="VIB18_000400"
     CDS             18300..21374
                     /locus_tag="VIB18_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8765432.1"
                     /translation="MTKGIRFQLLGSPRIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACKEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLAYINSQLGSQPVTAEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGDYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMVAHLLTESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(21405..22391)
                     /locus_tag="VIB18_000401"
     CDS             complement(21405..22391)
                     /locus_tag="VIB18_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEQ8765433.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSSSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHN"
     gene            complement(22577..24118)
                     /gene="hutH"
                     /locus_tag="VIB18_000402"
     CDS             complement(22577..24118)
                     /gene="hutH"
                     /locus_tag="VIB18_000402"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEQ8765434.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKIPLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCIPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(24129..25472)
                     /locus_tag="VIB18_000403"
     CDS             complement(24129..25472)
                     /locus_tag="VIB18_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEQ8765435.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(25692..26288)
                     /locus_tag="VIB18_000404"
     CDS             complement(25692..26288)
                     /locus_tag="VIB18_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEQ8765436.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     KSTVALRQTTFTLLDGYHRILMTLDKPITLSDLSHAKEISLTPFEPYAFEGDTRIVSR
                     GICQDMNLMYDDQYQGQLLPVWSDTLFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCLNQTSPAQTPVAVWAGLWYKT"
     gene            complement(26310..27983)
                     /locus_tag="VIB18_000405"
     CDS             complement(26310..27983)
                     /locus_tag="VIB18_000405"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8765437.1"
                     /translation="MVLSDIEIANSVSMEPISKVGDQLGIDKEALCLYGKYKAKINAR
                     QLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGAPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYRGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLT
                     KIVTKVYGGKGINLSPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(28001..28627)
                     /locus_tag="VIB18_000406"
     CDS             complement(28001..28627)
                     /locus_tag="VIB18_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEQ8765438.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQVIIEDLHTKSSRLQQDLLDAIDKDTEAFNLVSAVFDMPKETDEDRA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(28638..29537)
                     /gene="ftcD"
                     /locus_tag="VIB18_000407"
     CDS             complement(28638..29537)
                     /gene="ftcD"
                     /locus_tag="VIB18_000407"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEQ8765439.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRKLGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYNKQVLENHLLG"
     gene            complement(29626..31656)
                     /locus_tag="VIB18_000408"
     CDS             complement(29626..31656)
                     /locus_tag="VIB18_000408"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEQ8765440.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRFRPKDRIYGKPINEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWVSQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGNHDDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            31948..33213
                     /locus_tag="VIB18_000409"
     CDS             31948..33213
                     /locus_tag="VIB18_000409"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEQ8765441.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDVLAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIVEQMLPEVKKENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(33271..34803)
                     /gene="ahpF"
                     /locus_tag="VIB18_000410"
     CDS             complement(33271..34803)
                     /gene="ahpF"
                     /locus_tag="VIB18_000410"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEQ8765442.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHDSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVVTKDIVGEDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(34824..35384)
                     /gene="ahpC"
                     /locus_tag="VIB18_000411"
     CDS             complement(34824..35384)
                     /gene="ahpC"
                     /locus_tag="VIB18_000411"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEQ8765443.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            35791..35861
                     /locus_tag="VIB18_000412"
     tRNA            35791..35861
                     /locus_tag="VIB18_000412"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35823..35825,aa:Cys,seq:gca)
     gene            36370..36573
                     /locus_tag="VIB18_000413"
     CDS             36370..36573
                     /locus_tag="VIB18_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEQ8765444.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            36769..37230
                     /locus_tag="VIB18_000414"
     CDS             36769..37230
                     /locus_tag="VIB18_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEQ8765445.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEECISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            37230..39674
                     /locus_tag="VIB18_000415"
     CDS             37230..39674
                     /locus_tag="VIB18_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8765446.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKKAKGQMRNPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            39852..40142
                     /gene="groES"
                     /locus_tag="VIB18_000416"
     CDS             39852..40142
                     /gene="groES"
                     /locus_tag="VIB18_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEQ8765447.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            40178..41809
                     /gene="groL"
                     /locus_tag="VIB18_000417"
     CDS             40178..41809
                     /gene="groL"
                     /locus_tag="VIB18_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEQ8765448.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            42020..42371
                     /locus_tag="VIB18_000418"
                     /pseudo
     CDS             42020..42371
                     /locus_tag="VIB18_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678177.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(43028..44527)
                     /locus_tag="VIB18_000419"
     CDS             complement(43028..44527)
                     /locus_tag="VIB18_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8765449.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGQKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDLKAAQEKADKISLDRAEKTFKRLKAIEAKLVKEKPKNKKGLNRS"
     gene            44774..46414
                     /locus_tag="VIB18_000420"
     CDS             44774..46414
                     /locus_tag="VIB18_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765450.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALAPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(46503..47504)
                     /locus_tag="VIB18_000421"
     CDS             complement(46503..47504)
                     /locus_tag="VIB18_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8765451.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            48079..48459
                     /locus_tag="VIB18_000422"
     CDS             48079..48459
                     /locus_tag="VIB18_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8765452.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            48498..50834
                     /locus_tag="VIB18_000423"
     CDS             48498..50834
                     /locus_tag="VIB18_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8765453.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDELENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            50883..51035
                     /gene="rpmG"
                     /locus_tag="VIB18_000424"
     CDS             50883..51035
                     /gene="rpmG"
                     /locus_tag="VIB18_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8765454.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            51049..51225
                     /gene="secE"
                     /locus_tag="VIB18_000425"
     CDS             51049..51225
                     /gene="secE"
                     /locus_tag="VIB18_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEQ8765455.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(51461..52234)
                     /locus_tag="VIB18_000426"
     CDS             complement(51461..52234)
                     /locus_tag="VIB18_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEQ8765456.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            52360..53106
                     /locus_tag="VIB18_000427"
     CDS             52360..53106
                     /locus_tag="VIB18_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8765457.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSSGGLVLDFVS"
     gene            53122..54102
                     /locus_tag="VIB18_000428"
     CDS             53122..54102
                     /locus_tag="VIB18_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEQ8765458.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRKQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            54389..54709
                     /locus_tag="VIB18_000429"
     CDS             54389..54709
                     /locus_tag="VIB18_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8765459.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFIHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            54737..55045
                     /locus_tag="VIB18_000430"
     CDS             54737..55045
                     /locus_tag="VIB18_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8765460.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKDIDCQIDAYSQGKLAE
                     YAPLIDVALLGPQVAYTLDKSEAICKENGIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            55055..56359
                     /locus_tag="VIB18_000431"
     CDS             55055..56359
                     /locus_tag="VIB18_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8765461.1"
                     /translation="MAKMNMQNIIMPIMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGINDAIAGVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEPIGDAISKAWFGGQGIIGAIVIGLTVGAIYTAFIR
                     RHIVIKMPEQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            56570..58987
                     /locus_tag="VIB18_000432"
     CDS             56570..58987
                     /locus_tag="VIB18_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEQ8765462.1"
                     /translation="MTETKSPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAETASPERQAELLEIARICDKVPYEPAATFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEASIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWHALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQNHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            59000..59668
                     /locus_tag="VIB18_000433"
     CDS             59000..59668
                     /locus_tag="VIB18_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8765463.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     DSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            59725..60813
                     /locus_tag="VIB18_000434"
     CDS             59725..60813
                     /locus_tag="VIB18_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEQ8765464.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(60882..61391)
                     /locus_tag="VIB18_000435"
     CDS             complement(60882..61391)
                     /locus_tag="VIB18_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEQ8765465.1"
                     /translation="MSTDHHLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGYSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            61756..62571
                     /gene="sdaB"
                     /locus_tag="VIB18_000436"
     CDS             61756..62571
                     /gene="sdaB"
                     /locus_tag="VIB18_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEQ8765466.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(62812..63654)
                     /locus_tag="VIB18_000437"
     CDS             complement(62812..63654)
                     /locus_tag="VIB18_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8765467.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            64595..65791
                     /gene="speB"
                     /locus_tag="VIB18_000438"
     CDS             64595..65791
                     /gene="speB"
                     /locus_tag="VIB18_000438"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEQ8765468.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDVNGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWESQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            65793..66098
                     /locus_tag="VIB18_000439"
     CDS             65793..66098
                     /locus_tag="VIB18_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEQ8765469.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKPPMRVQQLSYPSDTDHS
                     SGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQKQINSLD"
     gene            66576..67505
                     /gene="prsA"
                     /locus_tag="VIB18_000440"
     CDS             66576..67505
                     /gene="prsA"
                     /locus_tag="VIB18_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8765470.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(67776..68012)
                     /locus_tag="VIB18_000441"
     CDS             complement(67776..68012)
                     /locus_tag="VIB18_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765471.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPAAHGPCD
                     DTHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            68496..71513
                     /locus_tag="VIB18_000442"
     CDS             68496..71513
                     /locus_tag="VIB18_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8765472.1"
                     /translation="MLIAPTVLGQEVSTNTETSTTTATTTPSAGTGKANGTAATTPSA
                     GTSTGEATVATATTTNGGSQSTPAVAEATPQPQAQTVTATTSTSSTSSSDEKSNKAAT
                     ATTSTSPSTPVVASNNSNQEASTEAETPMMDVEQYTVDNKETELKVKDGDKSKNGNSI
                     SKDTKLIRNRDGEQRDIVDIKREVKDNGDGTLDVTLKVTPKEIDKGADVMALLDVSKK
                     MSEDDFNNAKDKIKKLVKTLTSNSDNDEHKHNSRNSVRLMTFYREISKPIDISGKTDD
                     ELDELLDKLRQKAKDEYDWGVDLQGAIHKAREVFNNENNDGKKKSGKRQHIVLFSQGE
                     STFSYDIKNKDDKKLQKTRLTTVTTSNPLFSWFPIFDHTNRKADMLDDFDKLLSIAQK
                     FGVEIPSGIKIGLKTASAGNFLLGSLTGSDSLTDYLTLREYVADKLQETDFDYSNRVG
                     EGYHYHSFSERKLGGLPMESTFKTLLNTNVPKLDDKTWFGWTMNKLSLADKYHSFQKE
                     ILLKILEYLFYKREYHYYNHNLSAIAEAKMAQKEGITFYSVDVTVSKTTPKRVKRQTA
                     VRQGTAKKESEEERNKKFDEYLKKMSEGNDFLSNVEARDKFKDTLTELKIKDEFSDKV
                     TVQNNSEGKKYQGTSLTNDIPNVEHKQLQEKKGWLSSGNKESLTWTISKEQLKQAFED
                     GKPLTLTYKLKVDNDKFKTALEKKKRTKRSAPTENENSVTENIISNTTTYKINDQEVK
                     GNKLGDVNLTYSKLKVPVPQIDGHVIEPQAPKLPDLPPVIERGPVLDYTEESIYRLPL
                     GHGSNAPDTQVTIEEDTVPQRPDILIGGQSGPVDITEDTQPGMSGSNDATVVEEDTAP
                     KRPDILVGGQSDPIDIIEDTQPSVSGSNDATVVEEDTVPQRPDILVGGQSDPIDITED
                     TQPGMSGSNDATVIEEDTKPKRFFHFDNEPQAPEKPKEQPSLSLPQAPVYKAAHHLPA
                     SGDKREASFTIAALTIIGAAGLLSKKRRDTEEN"
     gene            71693..73636
                     /locus_tag="VIB18_000443"
     CDS             71693..73636
                     /locus_tag="VIB18_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8765473.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAISNSLEYQRQYKRVKKE
                     LDALKENSPKLGERSLYFRLVNKFLSWFGQVWDPLAIKETDHLLDLIGQVNYLVSNTE
                     FQAPEYQKAKNKLDLAVAGYELYLAREKERGDAPDYQVTQLTLAQLKTIKTKIQEALK
                     TFAQEVKTIQQTHPDLFPHAYVLNATTSAIDGKAYTFLVNSYYDVFYKQFLFTNTKDG
                     YNYNKEADNLTSYQDLIKELLDLKAEIDQLTKDKPTNDRLETLMWESKFTLSDSRRTS
                     RLSAYYTQEDYVNKVVLSEEAPNLRTAKEKVKTLKGILYDYYVDIKDPEKAKKYRVED
                     ETLPSQPEAPAKPEAPGQKPAEDEGSSQATEPANPSKEDSSTDASQGSHDSENPATDS
                     PSRPQAPDQGNHQSQVPNAKPQTDKTDTPNVPAPPQNTPNAPAIPRDTPKVPEAGGQS
                     GPAGNAEEKAPDSGPKESDQSSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTITD
                     APPTVSGHNASTQPQSVVEDPAPQRPDVLVGGQSEPIDITQDTQPGMSGSNDATVINE
                     DTKPKRVFHFDNKEPQASDKAAEQKLAPHDSHTTPQASDDTAAPHLPASGDKPEKVFA
                     LAALTMVAAAGLLSKKRRNTDKN"
     gene            73778..74074
                     /locus_tag="VIB18_000444"
     CDS             73778..74074
                     /locus_tag="VIB18_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEQ8765474.1"
                     /translation="MTKQDQLIVEKMEQTYETFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            74221..74505
                     /locus_tag="VIB18_000445"
     CDS             74221..74505
                     /locus_tag="VIB18_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEQ8765475.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            74929..76197
                     /locus_tag="VIB18_000446"
     CDS             74929..76197
                     /locus_tag="VIB18_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8765476.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            76184..76858
                     /locus_tag="VIB18_000447"
     CDS             76184..76858
                     /locus_tag="VIB18_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765477.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            76871..78088
                     /locus_tag="VIB18_000448"
     CDS             76871..78088
                     /locus_tag="VIB18_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765478.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            78182..78835
                     /locus_tag="VIB18_000449"
     CDS             78182..78835
                     /locus_tag="VIB18_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8765479.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            78832..80220
                     /locus_tag="VIB18_000450"
     CDS             78832..80220
                     /locus_tag="VIB18_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8765480.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVTESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKPGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            80322..81962
                     /locus_tag="VIB18_000451"
     CDS             80322..81962
                     /locus_tag="VIB18_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8765481.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTAD
                     TDTDDESETPKKDKKSKETASQHDTQKDHKSSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNNTNQSDSSDQSTPSPKDQSSQKESQNKDGRSTPSPDQQKDQTPDKTPEKSADKT
                     PDKAPEKGPEKSAKKTPEPNRDAPNPIQPPLAAAAPVFAPWRESDKDLSKLKPSSRSS
                     AAYVRHWTGESAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTG
                     LDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDT
                     IIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDH
                     GSTPEIPEHLRITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELG
                     YQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGS
                     ILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP"
     gene            82040..82291
                     /locus_tag="VIB18_000452"
     CDS             82040..82291
                     /locus_tag="VIB18_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765482.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
BASE COUNT        25709 a        16025 c        17453 g        23464 t
ORIGIN      
        1 agaattatta cagtatgtga aaatatatca gaaattgact aaataaaaga ttctgttata
       61 cttgttttat aatattcttt gacgataata tcatttttca acttactttg tttatgcact
      121 gtcactttgc tatgtgcaat acaaagtcat gttatttatc tcatactaaa aaataatgga
      181 taatagctat gttagactag tgatatgaag aaatattgct tttattgaat cgttagagaa
      241 tatgatattt caaggagaaa aatagtgatc gagttaaacg atgaattcat ccgaaaagag
      301 acgatagaac tggccaacga tggcccacga gtacacacca ctcaatatga aactaaagta
      361 ccccggcttc ataaatgcta tctgcttttc tttagcatta ttatcagttc tttaacaatt
      421 gcagtacctt ttttaacaga tgcagccaat ggtcttcagt cccaaaactt atatatagga
      481 atgatgttaa cgaaggggca acttccctat agtgatgctt ttacaacagg agggctcttt
      541 tactttgtta tcattgcatt aagttattat ttgggatcga cactttggct agtctttgtt
      601 caggtgtttt gtttttactt atctggttta tatctttata aactcattaa ttatatgaca
      661 ggctttcaaa aagtggcttt aactttttca attagctact atttgttgtc tgttagtctt
      721 ggttttgggg gattgtatcc tactcaactg gctatgccat ttatattaat atcggcttgg
      781 tttttaacta agtattttgc ctgtttagtg aaagatgagg catttattct ttttggcttt
      841 gtaggtgctc ttgcaatgct aattgaccca agtaccctta tcttttggtc ttttgcttgt
      901 gtgacagttt tttcttataa tataagccaa aagcatcttg caagaggttt ttatcaactg
      961 ctagcttcga tttttgggat gattttagtt ttttacacag caggatattt cattttgaac
     1021 ttacaagtgc taaatcctta tttatcacaa acgatgattt atccttttac tttttttaaa
     1081 tcaggaaact tatcgttgct ttttggactg gctattcagt tgttcttcgc tttggggctt
     1141 ggtcttttga caggaatggg gaatgtcatt aggcgattta aaaacaattc tgatagggtc
     1201 gtcaagtggc tatttgtcat ggtcattcta gaatctatac ttgtggctat attttcacaa
     1261 gactatcgcc cctatcatct tttacctctt ttaccttttg gattaatttt gactgctatt
     1321 cctgttggct atcagtatgg tataggatta ggtcagagta gtcatcgcag acgtcatggt
     1381 aaaaatggtg ttggtcgagt aatgatgatt tatcttaaga gacactttta tttgccaatt
     1441 ttaattgtag ggacaatact aatctgttct acttattgtt tcattagtag tattcctctt
     1501 aatcaggagc gtgatcatat tgctagttat ttagaacaga aactaaataa aactcaatct
     1561 atttatgttt gggatgatac ttctaaaatt tatttggaca gtaaagctaa atctgtttct
     1621 caatttagtt ctcctgacat caatacgcaa aaagcgagtc atcgaaaaat attagaagat
     1681 gaactattag aaaataaggc tgcttatatc gttgttaacc gctataaaaa cctgcctaaa
     1741 atcattcaaa aagtattatc tactaattac aaagtagata aacagataac gacaaaaagt
     1801 tttattgttt atcagaaaaa gtaatttaat atcaatatat tgtgttcgag caaaaaactt
     1861 gacacaatat attgattttt ttagttgtcg tgatataata gttccgtaag gagatttgat
     1921 atggtaagtt tagaagaaga caaggtgact gttcaacctg atattaaagt gattaaacga
     1981 gatggtcgcc ttgttaattt tgatagtaca aaaatctata gtgctttatt aaaagcaagc
     2041 atgaaagtaa ctcggatgtc gccacttgtt gaggctaaat tagaggctat ttctgatcgc
     2101 attatagcag aaattattga gcgttttcca actaatatca aaatttatga aatccaaaat
     2161 attgtagagc ataagcttct tgcagctaat gaatatgcta ttgcaaaaga atacattaat
     2221 tatcgtactc agcgtgactt tgcacgttca caagcaacag atatcaattt ttctattgat
     2281 aaattaatta ataaagatca aacagttgtt aatgaaaatg ctaacaaaga tagcgatgtt
     2341 tttaatactc aacgagattt aactgctgga atcgtaggga aatcgattgg tttaaaaatg
     2401 ttaccttcgc atgttgctaa tgctcatcaa aaaggagata tccattacca tgatttggat
     2461 tacagtcctt atacaccgat gacgaactgc tgtttaattg actttaaggg catgttagcg
     2521 aatggcttta aaattggtaa tgctgaagtg gaaagtccca agtctattca aactgcaaca
     2581 gctcagatct cacagattat tgcgaatgta gcatcaagtc agtacggcgg atgcacagct
     2641 gatcgcattg acgagttttt agccccatat gcggagctta actttaaaaa acatatggct
     2701 gatgctaaga aatggatcgt tgagactaag agagaaagct atgcttttga aaagactcaa
     2761 aaagatattt atgatgcgat gcagtctttg gagtatgaaa ttaatacgct ctttacgtct
     2821 aatggtcaaa caccatttac ttctttagga tttggtttgg ggacgtcttg gtttgaacgt
     2881 gagattcaaa aagctatttt gaccattcgg attaatggtc ttggtagtga acatcgcacg
     2941 gctattttcc ctaaattaat tttcacggtt aaacgtggct tgaatttaga accagattca
     3001 ccaaactatg atattaagac tttggcttta gaatgtgcga ctaagcggat gtacccggat
     3061 atgttatctt atgataaaat tattgatttg acaggatctt tcaaatctcc aatgggatgc
     3121 cgctctttcc ttcaaggctg gaaagatgaa aatgggcaag atgtgacctc aggccgtatg
     3181 aatcttgggg ttgtcaccct caatttacct cgcattgcta tggaatcaaa tggcgatatg
     3241 gataagtttt gggagctgtt taatgagagg atgctaatta gtaaggatgc tttaatttat
     3301 cgtgtcgaac gtgtcacaga agcaaaacca gcaaatgctc ctattcttta tcaatatggt
     3361 gcttttggaa agcgtttgga gaagacaggg aatgtaaatg atctctttaa gaatcgtcgt
     3421 gcaacagtct ctcttggcta tattggtctt tatgaagtgg cgtctgtttt ttatggtggt
     3481 caatgggaag gtaatccaga tgctaaagct tttaccttgt caattgtcaa ggcaatgaaa
     3541 caggcctgtg aggattggtc agatgaatat ggttatcatt tctctgttta ttcgactcca
     3601 tcagaaagtt tgacagatcg cttttgtcgt ttagatacgg aaaaatttgg cattgtgaca
     3661 gatattacgg ataaagaata ctatacaaat tcttttcact atgatgtgcg taagagtccg
     3721 acaccttttg aaaaattaga ttttgaaaaa gattatccag aagcaggtgc ttcaggtggt
     3781 tttatccact actgtgagta tcctgttttg caacaaaatc caaaggcctt ggaagcggtt
     3841 tgggactatg cttatgatcg tgtggggtat ttgggaacca atacgcctat tgataaatgc
     3901 tataattgcc aatttgaagg tgattttacc ccaacagaac gtggttttac ttgcccaaac
     3961 tgtggcaata atgaccctaa aacagttgat gtggtcaaac gtacatgtgg ttacttgggg
     4021 aatcctcagg cccgcccaat ggttaacggt cgccataagg aaatctctgc gcgtgtaaaa
     4081 catatgaatg gttctactat aaaataccca ggcctgtaaa ctcaagctgg gggagagccc
     4141 ttttgatgga aatatgatat gcttaaaagg ttgcttcatg caagcaatct tttattgttt
     4201 aatggtttct tagcaattgt gagataagaa taactaatcc aaaacgccta attagctgtt
     4261 agcaatcgga ctataagaag aaagagataa ggaagaaata atgggaaaat atcaattaga
     4321 ctataaagga atgcaacagg tggaacgttt ccatgagaag cactctacaa aaaaggcaga
     4381 taaaaaatcc cgagttcaag aactcaaggc tcggttttta gagaagtcaa aaaaacagga
     4441 taactaaagt atccaataaa gaaagaaggt tgagtatgct taatattggg attgtgggac
     4501 taggtgccat ttcacaaaaa gcctatttac catatatgag acagctgagt gacattactt
     4561 ggcatctatc aacgcggaat gcagcagtac gtcagcaggt cggtcagtta tttggtcacg
     4621 ctattcttta cagtgatgtc aaggagttgt caaaaacaaa cttagatggg gtctttattc
     4681 atgcggccac atcggcccac gcagagttgg ctagtttatt tttaaatcag gggatcccag
     4741 tctttatgga taaacctata gctgacaatt acctgatgac aaagaacctc tatgacttag
     4801 ccaaagaaaa taagactttt ctgatggcag gatttaacag gcgttttaca cctcgtgtca
     4861 agaagttgtc aagtttgtca actaagcgta aagtggctgt tgaaaaaaat gacttgaacc
     4921 ggccaggaga tatgactttt aagctctttg atttctttat ccatccttta gatacagcct
     4981 tattcttgac agaagggacc ttactaaaag ggcattttca atatcatctg gaagcaggct
     5041 tactgagtca agttatggta accttgatga ccgaaagcat gacgactaca gcttctatga
     5101 atttacaatc agggagtcgc cgtgaggtaa tggaagttca acgggctgaa gaaacttatc
     5161 atttagagaa cttagacgag ttatctattt ataaaggtac tgaaaaaagg gtgcttggct
     5221 ttgcttcttg ggacaccacc ctgcacaaaa gaggttttga aacaatgatc gatgcctttt
     5281 tagaagctat tagcacaggc gtcaatcctg tcagccctga gtctagtctt ttaagccact
     5341 ggatttgtca acagattgct gcctctcagc tttcttatgg agagttaaag gtagagttgc
     5401 ctaaggatta ggaattaata tggaaataag acgaccgact ttggaagata aagatgctgt
     5461 attgtcaatg attaacgaat ttttagagca aaaaagtgct acagatgggt tatggcattt
     5521 taacgtcaat gactttaact atgaaacatg gttggaagat tccttgcgac aggaaatggg
     5581 tttggccagt caaggagtgc ctgctattca atacgtcgca tttgatgaga aaaatcaagc
     5641 tttgggattt ttaaacctta ggttacgttt aaatgcctca ttacttgaaa aaggtgggca
     5701 tattggttac tctgtccgtc ccagccagcg tgggaaaggt tatgccaagg agatgcttaa
     5761 acaagctgtc agctgtgcga tttccaagaa tatcacgaca attttggtaa cttgtgatga
     5821 gactaatgtt gcaagccgag cagttattgt ggctaacggc ggtatcttgg aagatagtcg
     5881 aggtggaacg gaacgttatt ggattgaaga acaaagaggc gataagtgat ggcagaaaag
     5941 tgttggaata atcctaagcc aaaggaatgg caggcagagg agttaagtca aggccggatt
     6001 attgactata aggcttttaa ctttgttgat ggtgaagggg ttcgtaattc cctttatgtg
     6061 tctggttgtt tattccattg caaggggtgt tataatgctg cgacttggtc ttttaaggcg
     6121 ggaatgcctt atacgcaaga acttgaagag cagataatga cggatttggc acagccttat
     6181 gttcagggac tgacactttt aggtggagaa ccctttttga atacgggtat cttaattcct
     6241 ctgattaagc gtattcggcg tgaattgcca gaaaaagata tttggtcttg gacgggttat
     6301 acttgggaag aaatgatgct tgaaacacca gacaaactgg aaatgttgtc cttaattgat
     6361 attctggtag atggtcgttt tgatatcaca aaaaagaacc tcatgttgca atttagaggc
     6421 tcttctaacc agcgaattat cgatgttcaa aagtctttgg ctgctaaaga agtgattatc
     6481 tgggataagt taaacgatgg ggaccaaacc tttgaacaaa ttagtcggga ggatttgctt
     6541 taagaagctg acttatccac atgatttttt tgaaaaggtc atgtgaaaac aggtccttta
     6601 agggtgaatt ggggagaaag taattgttat ttcctggttt tccccacatt atcctcatag
     6661 ttatccacag gttgtgtata agttgtagaa ttgtgaataa agactaaaaa agaggcctag
     6721 gcctcttttt tgatatagac aaattcatga tctgttgata ggtctggatg gtagtaaaaa
     6781 ccagcaaaga caaggctttt aaggctgtca acagtttggc aattattttc catacaggca
     6841 gtgagaaatg cacctcgtgc cttttttgaa atggtggaat gggttttgaa ttggccctct
     6901 ttttctgcca taaacttggg acttatccac aattgtttac agtctttgga aaagacatcg
     6961 tcaaattcac tggataaaag ggaaatcact tggggatgct ctttggcaaa ctgattataa
     7021 cagggccgcc agtaagactt gaggctttgt ccttcaattt ttattctggt gtgaaaatca
     7081 tggcggtgct ctgcgatagg atgattagcg ggaatgatac cgtaaaagga tgaggtgatg
     7141 taaacttgct gggtgaggta agcctgttct tgggtagtga gcttatcgcg cttgatatgg
     7201 cggtacataa ggccattgaa cagttggtag gcagggtaag ccaagctttg ttgagaggcc
     7261 atgtcttgcc agcgttgctg ttctttttta gctgcctctt ctttgatacg ataggatttg
     7321 gccaagtcct ccgtggtcat agctgccatg atttttaaaa tggcttggct gtcttgtgga
     7381 aggaggtgtg ggtgagattc cttagggatc atcatttctt ttgcggttgg aattaaaaag
     7441 gttagcatag tgttattgta gtaaagttac ttgctttctg tcaagaaaac tagtcttgtc
     7501 caaggatgac gttcacacgg ataccttcct cgtcttctgt cgtgaaagaa gaagaatctt
     7561 cttgtaaaat agctaggccg tgtaatcttg cttttttgag agtggctgaa aaaagcaggg
     7621 gcgtctcaat gtgaatggtt aagaaggcta agcctggagc accttcttgg tgttttttga
     7681 ggtaaggggc tgaccagtga ttgaatgtaa ggtgatgatg gtagttccct gaagcaatcc
     7741 agctagcact tggaatggtc attttatcgc ctaaatcaaa aaccttttga tagagaagtg
     7801 aagaagccag agcatttttg acactcagat ggacatggcc aatgcgtgtg tcttgagcta
     7861 gtaaaaagtg cttggggata tctgtcaact gctccaatat gcttttggta tccgtgggct
     7921 cagtcacacc aataatttga ccattgtcgc ggatatccca atgctcaaca gctttgtcat
     7981 gatagatttc aatcccatta ccctcaggat cgctgaggta gatagcttcg ctatggccgt
     8041 gatcagctgc tccttctaaa gagatacctc tggttaagaa ataattgaga acaagtccca
     8101 agctatgacg atcaggaact aaaaaggctg tgtgataaag accataagcc ttatttgctg
     8161 gtaaaggtgt ttgtcgtaac tctaagataa cggttttacc gtctgtagtc aattgacgag
     8221 atgtcgtgtc ttgtgagaga acctgtaaac cgataatact tgtgtaaaag gttgtcatct
     8281 ttgctagatc ggtaacattt agagaaaccg ttcctaaaga gatggttgag ttgtaagggt
     8341 atgtcatcct attacctcca aaaactaatt aaatctatca taaccaatca gtgtcaaaaa
     8401 gaaaagtagg cacaaataag tggtataggc actaaaaagt aactcattta tcagccctat
     8461 cttgtttctg ttctctctaa tagtctataa tgggttataa gttacaaaaa gatactaaga
     8521 ggagctgctg cctatgctga aaaaaagacc ggcttgtccc gtagaaacga ccttatcggt
     8581 aataaataga aattgttaat attaagagac ttgctaaagg gaccttgcgt tttgggcagt
     8641 tgaagtcctc aataggtttg gtcagtcaaa aggtacttac tgcacaatta agggctatgg
     8701 aagcagacgg attggttcat cgggaagtgt atgcagaagt gtcacctcgg gtggagtatt
     8761 ccttaacaga aactgggttg agcttagctc ctgttattga agcgatgtcg gattggggcc
     8821 aaacttacca agaaaaacat gccgatttat ttgaagaagg ctagaggaaa gagttgtccg
     8881 agcatactga gacttagaga agctgatagt ttttaaaaaa tgatattatc acattcttta
     8941 cagtttgata aaattacttt ttttctataa aaagacttgc gctcatctca cgaatatgat
     9001 aatataatat caagtctgtt tgagaaaaca gaagctcagg tcaagtaagt gcacacttac
     9061 aataacacag ttgataatgg ggaaactcag agtcaagaaa aagaaaagca agccttgcat
     9121 tttgcaaggc ttttttctgt ctttattttg gtctgcgccg agcaaaatct aaaaatttaa
     9181 atttttccag tttatggcga ctctcggtga attggaattg gttattattg gaaaggtaga
     9241 ctttggattt gacggaaaca acatgttggt ctgatccaag gtcaagtaaa attttatcac
     9301 gatcggttat ttggtcaatg gtaacctctt tgagggcaaa gtcaatggcg agatggagtt
     9361 ccttttccaa atattgataa atagaatgct ctgcgatttc ccttgttatt attggcacca
     9421 aagttttact aaggtaatca atgtctaaga cggaagccac accctcaaca acgcgttggc
     9481 gtgtaacacg ccagaccaag ctgtttttgc taaaaccggt caattttgaa agtgtctcat
     9541 ccacaatcag tttatcaatg gcaatgacgt tggtcttaga atctagattt gagtaagaga
     9601 cgagttcctg ataactagtt agttctgaga tagggaacat gatctgatga tgtttaatca
     9661 cttgggtgcc acgtccttgt tttttgagga taagacctgc ctttgtgaga agtgagagag
     9721 ccttgcggac ggtatctcgg ctagcttggt attgttgact caattctatt tcagtaggta
     9781 aaaaatcccc ttctttgtaa aagtctttgt ttatttttgt ttcgaggtct ttataaatac
     9841 gttcatactt tgtcataggg taaattacct ttccatttgt ctattttttt acagacaaca
     9901 ccttttattt taccaaaata atggcttttt tggcacaaac aacttgcaga caaatttgca
     9961 atcgattaca ataaaggtgt caatcatatt ttatctaaga atttgaatat ttcattttga
    10021 cgttgcttgt taaaagcaac tagaacaaag gactagggga tgtcacatgg gaaaatttga
    10081 acaggatgct aaaagtcttc taactgctat tggcggtaaa gaaaacatca aggctgttac
    10141 acactgtgca acgcgtatgc gttttgtttt gaatgataat aataaggcaa atgtcaaaaa
    10201 gattgaaaaa atctctgtag ttaaagggac atttaccaat gctgggcagt ttcaggtaat
    10261 cattggtaat gatgttccag ttttttataa tgactttaca gctgtttctg gtattgaagg
    10321 ggtgtctaaa gaagctgcca aatcagcagc taaaagtaat caaaatgcct tacaacgggt
    10381 gatgaccatg ttggctgaga ttttcacacc tattattccg gcgattattg ttggggggct
    10441 tattttaggt ttccgtaata ttttggagag tgtgcctttt gaatttcttg ggcagcaggt
    10501 cgaaaaaggg aaattagttt ttgatgcagc tggggatcct gtttggaata cgattgtgag
    10561 ggtatctcct ttttggtcag gggttaacca tttcttgtgg ttaccagggg aagctatttt
    10621 ccacttctta ccagttggga ttacttggtc tgtgacgcgt aagatgggaa ccactcaaat
    10681 tttagggatt gtccttggta tctgtttggt gtcaccacaa ttattgaatg cctatgcggt
    10741 ggcaggaacg cctgctgctg agattgccaa aaactgggtt tgggattttg gtttctttac
    10801 tattaatcgt attgggtatc aggcacaggt tattccagcc cttttagctg gtctgtccct
    10861 tgcttatctt gaaattttct ggcgtaaacg gattccagaa gtggtttcaa tgatttttgt
    10921 gccattcctt tctttgattc cagctttgat tttagcgcat acggtattgg ggccaatcgg
    10981 ttggactatt ggtaaaggga tttcctttgt tgtgttagct ggtttgactg gtcctgttaa
    11041 atggctattc ggtgctatct ttggtgcctt gtatgctccg ctagttatta ctggtttaca
    11101 tcacatgaca aatgccattg atacccaatt aattgctgat actgcaactc gtacaactgg
    11161 tttgtggcca atgattgctc tttcaaatat cgctcaaggg tcagccgttt ttgcttatta
    11221 tttaatgaat cgtcatgaag aacgtgaggc tgaaatatcg cttcctgcag caatttctgc
    11281 ttaccttggg gtaactgagc ctgccctttt tggggttaat gttaaatatg tttatccctt
    11341 tgtagccgga atgatcggat caggtattgc gggtctctta tcaacaacct ttaatgttca
    11401 ggcaaatgct attggtgttg gtggcttacc aggtttcatg gctatcaatg tgaagtacat
    11461 gattccattc ttcatctgta tggcagtagc cattgtggtg ccgatgtttt taaccttctt
    11521 tttccgtaaa tcacatatca tgactaagac agaagatgaa gctaaactac ctgagacacc
    11581 cgtttcggat gctcctgtag caactgctcc acataagact atgcaaggaa cagttatcac
    11641 tttaacaagc cctttaacgg gtgaagttaa agcgttgtct gaagctgttg atcctgtctt
    11701 tgcacaggga gttatgggcc aaggtgctct tcttcaaccg acagaagggg tgttagtagc
    11761 gccttgtgat gctgaagtat cggtcttgtt cccaactaaa cacgctattt gtttggtgac
    11821 gactgaaggt ttggaattat tgatgcatat tggcatggat acggttaact tagatggtca
    11881 aggatttgaa gctttggtga agcaaggtga tcaggttaag gctggacaaa cattgattca
    11941 atttgatata gcagctattt ctgaagctgg atacgccact gaaacgcctc ttgtggtgac
    12001 taatcaagat gtttttacgg taactgttga aggtagttta ccgcgtcaga ttaaggttaa
    12061 tgataagtta gcagtagcgg tgaaaaagta ggtttactaa gagaaaacgt tcaggaactg
    12121 agatcagttc ctgaaactat tttagggagg aaaactcatg acaattgata aaaagaaagt
    12181 cgtctatcaa atttacccaa aatcctataa ggacacgact ggaaatggtg tgggagactt
    12241 gcgagggatc attgataaat tgccttactt acaagaacta ggaatagata tgatttggtt
    12301 gaaccctttc taccctagtc cacaacgaga caatggctat gatgtttcag attatacggc
    12361 ggtcaaccct gattttggga caatggctga ttttgaaaat ttggtaaaag ctgctaagga
    12421 gcatcagatt gagttaatgt tggatatggt tttgaatcac tgttccacag accacgagtg
    12481 gttccaaaaa gctttagcag gagaccctta ttatcaggat ttctttatct tgagagatca
    12541 gccgactgat tgggtttcca aatttggtgg gaatgcttgg gcgccttttg gagatacagg
    12601 caagtactac ttacacttgt ttgatgtgac acaggctgac ttgaattggc ggaacccaca
    12661 tgttcgtgag gaattggcta aagtggttaa tttttggcga gataaaggag ttaagggatt
    12721 ccggtttgat gtgattaacc tgattgggaa agatgaagag ctggtggatt gtccggtcaa
    12781 tgatggtaag ccagcttata cggatcgtcc tattactcac acttatcttc atgatctcaa
    12841 tcaagccagt tttggtcagg atgattcgtt tatgacagta ggggaaatgt ctgccacgac
    12901 tattgacaac tgtcttttat acacggctcc cgaacgtgag gagctatcca tggcttttaa
    12961 tttccaccat ctaaaagttg attatgagaa cggtcagaaa tggactatta tggcttttga
    13021 ttttgcagcg ctgcgagact tattccatgc ttggggtgaa ggcatgggtc agggcaatgg
    13081 gtggaatgcc ttgttctaca ataaccatga tcaaccacgt gccctgaatc gttttattga
    13141 tgtaacacat ttccgaaacg aaggtgcgac gatgttagcg gcttccatcc atttgtcacg
    13201 aggaacgcct tacatttata tgggtgagga gattggcatg cttgatccag actttgatag
    13261 tatggatgat tatgtggatg tggaaagtct caatgcttac tcaagcttat tagtctcagg
    13321 taaaagtgca gaagaagcct ttgccattat caaggctaag tcaagggaca atgccagaac
    13381 accaatgcaa tgggatgcta gtgaacatgc tggctttacg actggtaagc cttggttaga
    13441 ggttggcaaa tcttatcgag acatcaatgt cgaaacagaa aaagagggac gtatttttcc
    13501 tttctaccaa cgcttgattg ctttgcgtaa ggaactccct attattgctg aaggggacta
    13561 tcgggctgct tttaaagata gtcaggctgt ctacgccttt gaacgccatt taggtgacca
    13621 gtgtttgctt gttctcaatc atttctatgc tgatgaggcc gaactggaat tacctccacg
    13681 ttatcaacat ggacaggtct taatcagcaa ctatgagaaa gtttctattt gtgaaaaagt
    13741 gatactgaaa ccttatcaga cacttgctat cttagctgaa aactaactaa aagcctgagg
    13801 ttaggcctca ggcttttggt gattgtcacg aaaaaagaag ttttctcata tatttatttt
    13861 taaactctta ttttttctaa ataaaaacaa ttgagataag ttattttagc taaattttgg
    13921 tacaatggaa aagattataa gtagagttta agataaagat tctacaaatt taaaatgata
    13981 taaggagata cgaatgacaa cttatcaaga tgatttttac caggctgtga atggaaagtg
    14041 ggctgaaaca gcagttattc cagacgacaa gcctcgaaca ggtggatttt cagacttagc
    14101 agatgaaatt gaggcattaa tgctagacac tacagatgct tggttagcag gggatcatgt
    14161 ccctgatgat gctattttaa aaaattttgt gaaattccat cgtttggtgg ctgactacgc
    14221 taaacgtgat gaagttggag taagtccaat tctcccttta attgaagaat atcagtcctt
    14281 aaaatctttt tcagaatttg ttgctaatat agcgaaatat gaattggcag gtttaccaaa
    14341 tgaatttccc tttagtgtgg caccagactt tatgaatgct cagctgaatg tgctttgggc
    14401 agaagcacca agcattcttt tgccagatac aacatactac gaagaaggca acgaaaaagc
    14461 tgaggaattg cgtggtattt ggcgtcagtc gcaagaaaag cttttacctc aatttggttt
    14521 ttcaacagaa gaaatcaagg atcttttgga taaggtaatt gagctagata agcaattggc
    14581 caagtatgtc ttgtctcgtg aggaaggctc agaatatgcc aaattatacc atccttatat
    14641 gtgggctgat tttaaaaaac tagctccaga gcttcctttg gatagcattt ttgaaaagat
    14701 tttaggccaa gtacctgaca aggttattgt tcctgaggaa cgtttttgga cagaatttgc
    14761 agccacttat tactctgaag ccaattggga tttactcaag gctaatttga ttgtggacgc
    14821 ggctaatgct tacaatgctt acttgacgga tgatattcgt gtggaatcag gcgcttattc
    14881 gcgcgctctt tcaggaacac ctcaagctat ggacaaacaa aaagcagcct tttatttggc
    14941 gcaaggaccg tttagtcaag cgcttggctt gtggtatgct ggtcaaaaat tctccccaga
    15001 agctaaggct gatgtggaaa gtaaggtagc acgcatgatt gaggtttata agtctcgtct
    15061 agaaacggct gattggttag caccagccac acgtgaaaaa gccattacta aattaaatgt
    15121 tatcacgcca catattggtt acccagaaaa attaccagaa acctatgcta aaaaagtgat
    15181 tgatgagagc ttgtcattgg ttgaaaatgc acagaacttg gctaaaatca cgattgctca
    15241 cacttggagt aaatggaaca agccagttga ccgtagtgag tggcatatgc cagcccactt
    15301 agtcaatgct tattatgatc ctcagcaaaa tcagattgtc tttcctgcgg caatcttaca
    15361 agagccattt tattctttag atcagagttc ttcagccaat tatggaggaa ttggtgcagt
    15421 cattgcgcat gagatttcac atgcctttga caccaatggt gcttcctttg atgaacatgg
    15481 tagcctaaat gattggtgga cacaagaaga ctatgctgcc tttaaagagc gtacagataa
    15541 gattgtggcg cagtttgacg gcttagagtc acatggtgct aaggtcaatg gtaaattgac
    15601 agtttcagaa aacgtcgctg acctaggtgg ggtagcttgt gctttagaag cggcacaatc
    15661 agaagaagac ttctcagccc gtgacttctt tattaacttt gcgacgattt ggcgtatgaa
    15721 ggcccgtgag gaatacatgc aaatgctagc tagcattgat gttcatgccc cgggtgaact
    15781 gcgaacaaat gtcaccttaa ccaattttga tgctttccat gagacctttg atattaaaga
    15841 aggcgatgct atgtggagag ctccgaaaga ccgtgtgatt atttggtaat taggtagttg
    15901 ataaaccttc aaatgcctgt gattataaaa atgactgatt ctgtgaaaca caggatcagt
    15961 tttttgcttc cttattggtg tccgttttga tacaacaaaa agacaaccct caggaaagaa
    16021 ggttgccttt tttagactta tcagaaataa gtgattagtt gttaagggca gcagccatag
    16081 tagctgcaac ttctgattca aagtcgttag cttttttctc gataccttca ccaacttcaa
    16141 aacgtgcaaa agcaatcgct ttagcgttta ctgagtcaag gtaagcttca acagttttgc
    16201 tgtcgtccat gatgtaaact tgtgcaagaa gagtgtaagc ttggtcaact ttagtgttgt
    16261 caagcatgaa gcggtccatt ttacctggga tgattttgtc ccagattttt tctggtttgc
    16321 cttcagcagc aagttcagct ttgatgtctg cttcagcagc agtaatcacg tcgtctgata
    16381 attgagcttt tgaaccgtat ttcaagaatg gaagtgctgg tttgtcaacc attgcacgcg
    16441 attcgttgtc aagttcgata gcgtggttca attgagcaag ttcatctttg atgaattgtg
    16501 catcaagctc agtgtatgaa agaacagttg gtttcattgc agcgatatgc attgatactt
    16561 gtttagcaag agcatcgtcg ccgccttcga caactgagat aaccccgata cggccaccat
    16621 tatgttggta agcaccgaag tgttgctcat ctgttttttc aatcaaagca aaacgacgga
    16681 atgagatttt ttctccgatg gtagcagttg cattaacgta agcttcagca agagtttcac
    16741 ctgaaggcat aacaagtgca agtgcttcat cgttgttagc tggtttgcct tcagcgataa
    16801 ctttagcagt tgcgtttacc aattcaacga attgagcatt tttagcaaca aagtctgttt
    16861 cagcgttaac ttcaacaaca gcagcaacgt taccatgaac gtaaacgcct gttaaacctt
    16921 cagcggcaac acggtcagct tttttagccg ctttagccat tcctttttca cgaagaagtt
    16981 caacggcttt gtccatgtca ccatctgttt caacaagtgc ttttttagcg tccataacgc
    17041 cagcaccaga tttttcacgt aattctttta caagcttagc tgtaatttct gccatgtgta
    17101 gtatcctcca aatgatattt gttttggttt caaaaaacga gacagagcgg tttgctttct
    17161 gccccgtttg gttttcggtt gttaaagaca aacaaagttt gccataagag ttaggaactc
    17221 tgtgctaatt aagcgttgtc gccttcgaca acttcaacga tttcttcgat tgaatctgct
    17281 tgagtgtcag cttcaaaagc aacgtctgca tcttcacctt gacggccttc gataatagcg
    17341 tcagctaatt tagcagtaat taatttaacg gcgcggatag cgtcatcgtt agctggaatg
    17401 atgatatcga tatcatctgg atcagcgttt gtatcaacca tcgctacgac tgggatacca
    17461 agttttttag cttctttaac agcaatttgt tctttatgtg ggtcaacaac gtacattacg
    17521 tctgggatac gaggcatatc ttcgataccg cccaagaatt tttcaagacg agcgcgttgt
    17581 ttgttaagaa gtgcaacttc tttcttagga agaacgtcaa aggttccttc ttcttccata
    17641 cgtttgattt ctttcaaacg agcgatacgt ttttggatag ttccccagtt ggtaagcgtt
    17701 ccacccaacc aacggtggtt gatgaagtat tggcctgcac gcgttgcttc gtcagcaact
    17761 gcttcagcag cttgtttttt agtaccaacg aacaagatga cagcatcgtt tgctgcagca
    17821 tcacgaacaa attcgtaagc ttggtcagct aattttacag tttgttgaag atcgataacg
    17881 tggataccgt tacgctctgt gaagatgtat ttagccatct tagggttcca gcgacgagtt
    17941 tggtgaccaa agtgaacacc agcctcaaga agttgtttca ttgaaattac tgccatgagt
    18001 agtttctcct ttataaaatg ttttttcctc ttccagactt cgacttgcag gctaacctag
    18061 cggcaacaag cccacaattg gtctagaatg agtatttgcc gtctacacga ccttactata
    18121 gtatcaaaaa aagaggttaa aagcaaggag aaatgctatg gattccctta tttttgagat
    18181 gactagcttc tttgtttatt ggtaagtgtt aagacaagct tttgctcatt ttgggtgaca
    18241 cttgccaaat cgttttattt aagatatagt gaacttgact aatttttgga ggcgttttca
    18301 tgacgaaggg tattcgattt caattgcttg gcagtcctcg catttttctt gatgacaaag
    18361 aacaattttt tgcctttgcc aaagcaaatg ctctccttta ttacttagtg gttaatggat
    18421 ctgttagccg cgaggtggcg gcgagtctac tttgggaaaa taagaacacg caaacagcga
    18481 aaaagaattt acgaaacgct atctaccagg tcaataaagt cttgcaagct gatgtgatta
    18541 tttgtcccaa tcgcaacctg ctggttttga ataaaacact tgatatcaaa acagatatta
    18601 acctttttct ggctgatccg ctagctcact tagaactcta ccaaggggag tttttgcagg
    18661 gcttttacct taaaagtggt gaggaatttg atctttgggt ttcaaaaatg cgtatgcagt
    18721 atgaacaggt atacctaaaa gcgtgttacc aaaaaattga agaaaagctc tctttagatg
    18781 ccattgaaga tgtcgaggaa catttaaaac agcttattga acgtgatgaa tttgaagaga
    18841 aaaattatca gctcttgatg aggctttatc agcaggggaa ttgtcctggt aaggtcatcg
    18901 aaacttatta tcagttggct aatgtgttgg ataaggagct agggattcag ccaagtttgc
    18961 aaagccaaca gatttatcag gaagtggtcg ctaaagatcg taatgaacgc aaaatcaagc
    19021 attttttgcg caacagtaat cattttttgg ggcggattga tgagattaag cagctggaaa
    19081 actattttgc caactgtttg gcctgcaaag aggtaggagc tctgctctta attggtgata
    19141 cagggattgg gaaacgaacc ctagccagac aggtcttagc caatcaaacc caaacgtttc
    19201 aaattgtcac agctaaatgt tttcgtgaag aggctatgga ttccttattg ccttggcgta
    19261 atatcttaga tggcctggga gatttggtga ttcaaaaccg cttattgacc accaaagctt
    19321 ggaaggctgc tcttaaacgc tgttttcctg tggcaaccat ttttcaagaa gataacaacc
    19381 aaccctttat caaggaccac accagcttgt tggtttcctt tattgttgat attttacaac
    19441 atttggcaga aatcaaggcg ctggtaatcc ttattgagga ttgtcactgg atggatgagg
    19501 atagtttgac cttgttgcaa cgggtcatga atcaattggt ccactatccg attgcttttg
    19561 tcttgaccaa gcatctagga acgactcctg agctcggtct ttgtttgaat gctttgatga
    19621 gtcaggggcg tttagaaagc atttgtttgg agccttttaa tcggcaagaa agtttggctt
    19681 atattaacag tcaactgggt agtcagccag tgacggcaga agaaatggag cacctctatc
    19741 aagccagcca aggcaaccct ttctttttgt cagaatacac tcaggcccta ctgcgtcacg
    19801 aaaaatttgt gcctttaacg cctgccatta aggctaagtt gggtcttaaa ctagctaatc
    19861 taagtagtcg tgatgacgca ttgttaaact atttgtcttg ttgtcggagg cctatccctc
    19921 taaataccct cgctcaattg atgttactgc ctttagaaga agtgatcgag atggtggata
    19981 atctggggga ctactatatt ttggtagaag aaagcgtagg agaggaagtg ttgatttcat
    20041 ttcgtcagcg aattattcaa ctctatagtt atgaccgttt atctttgtca aaaaggcgtt
    20101 tattgcacgg acaaattgcc aaacggttag aagatttact gcctattttg acaccaagcc
    20161 ctcacttatt agatgacatt gcttaccatt atcaggaatc acggcaggtg attaaggctt
    20221 tggaatacaa ccttaactat ctagatgcta ccttgccatt tcagcatgag ctgtttccca
    20281 tttattcaaa gagtattggc tccttggaaa agtcagatcg tgaccatcaa cgcttaatgg
    20341 aagagcagtt tgataagatt cggcaaagca ttgcggattt ggaactgacc tatgataata
    20401 accgtgattt ccagcagttg cttattcgtt tttcttacct tgaaggccgt tatgatattc
    20461 gaacagggag gtatcaagaa gggattaaac atattcaaaa ggtcatcgct ttggcaaccg
    20521 agctaaaaca gccctccttc ttgctagaag gctatcgcca gttaattcat tactgtatcc
    20581 aagtggaaaa caagccagaa atgcgttatt acactagtct ttcattggag gcagcggttg
    20641 ctgctaatca ttttgaggcc attgcgatta gtttgcggtt aaacggtctc tatcatttga
    20701 ttattgggga gttaaatgag gcagagcgtc tgcttcaaca gtcgattgac ttctttaagg
    20761 tgacgccagg cttgcaagct aactatgcga ttcagattgc tgctgcctta gattatttgg
    20821 gggagattgc ccagattcgc tatcaatttg aaaaggccgt tgcttaccaa aaacaagcca
    20881 ttgccttgac cgaaaacaag ccagctgagt tatcggtgag tattttttat attggattag
    20941 ggatttccta cttttattta gctgattttg aacaagctga gcaaatcttg agtttggcta
    21001 aggaagcttt ggtcaatcat agttatcctt ggaaagaaac gcaacttgaa atttacctgg
    21061 ccatgattca atggaaaaag ggcaattatc agccagcctt gaccctactt gattacagag
    21121 aaaccttgat gtctaggtat cgcaatccgc gtgataaggg cttggttttc tatttgatgg
    21181 ctgtggtcaa gtaccaattg atatttcaag gagctaccct aagtcagcag gaaaaagaaa
    21241 tggtagctca cctgttgaca gaatcctttg agtattatta tgaaattgct agtactaacc
    21301 tcaaccctta ccgagattgt catttggtga gtgagttgaa cgatttgcgt caacaattat
    21361 ctgctaaaag ctaaggaaaa ccctctgatt cacatcagag ggttttagtt atgttgtgcc
    21421 ataatctgta cgaggtaaaa gataaaggtg gctgctaaat tggcggtgtg gttatcaata
    21481 tcgtgtggtg gtgaaacctc aaccacatca aagccaacta attttccgct agctgcaatg
    21541 tgttgcaaaa ctaagacggc aagatttggg tcaacaccga gggactggat agcactaacc
    21601 ccaggtgcag caccaactga gaaacaatcc atgtcgatag tcaggtagac cctttcttgc
    21661 ccttctaaga aacggtcaat ggctcggcag accttttgat ggcccatttg gtagatgtct
    21721 tgacctgtta aaaattgaat gcccttggat tttgccacaa agtcaaatag gaaaaggttg
    21781 ttattatgtt cttgaatgcc taaaacgaag tatttaaaga ggcgtttgtc agcaacggca
    21841 tcatcaaaca tctggcggaa tcctgtacca gaattgggac ctgtttggtc gtagggtctt
    21901 aaatcaaagt gggcgtccat attgatgaca gctaggtcat cacttgagga taggctttgg
    21961 cgtaggccta agtagtggcc gtaggcggtt tcatggccac ctcctaagac gatgggtttg
    22021 agattgaggt cacacatccg tttgatggct ttgcttaaac tgttttgcag ttgttccaaa
    22081 gagcgattgg ggccgtcaat gttacccaca tcgtaaacca taacttggtt tcctaaatgc
    22141 caagggaatt tggcgagctg ggtacgtata gcagctggac tttcgaccgc tccgacacga
    22201 ccattattga tataaactcc cttatcactt ttaaagccaa tcaaggcaaa atgtgtccct
    22261 tcaaatgggg ttagtgagct gtcgttaagg tcaaggaaag tcatgaccat gccccatttg
    22321 gcagtatata agtcatcgtc gatcccacca tgataatagc tagtggtgga tgggtagtaa
    22381 tcttctagca tgcgcgtcat ctcctttagg attatgatag caaaataaaa cttacagtca
    22441 acactttctt ggcctttgtc actgcttttt aggaatagca gagcaataaa atcgtctgct
    22501 tttggtcccg gttagttagt ctaaagaggc catgacctct gccacagccc ctctagttaa
    22561 agaagtacct tattcactaa aattggatac tcaactcaac tgcctgctca accgcttcga
    22621 ggaagcttgg gtcttcaatg actgctgatg ccttgtttag ttcatcgtag atttcgatgt
    22681 gtttatcgtg ttcgataaag ttgacttcct tgcggaagag atcgtaggca accttagtcc
    22741 ctttacctag ttcatgattt tcaggtttga gatcaagggc ttggcaggct gccatgattt
    22801 cagtagccac gatgcggcga gaatttttaa ggatttcaaa ggccttgcga gcagcggtgg
    22861 tgcccatgct gacaaagtct tcttggttct cacaagatgg gatagaatcc acactggctg
    22921 gatgtgccaa aaccttgttt tcagaagcaa gagaggcaca ggcgtactgg gtaatcataa
    22981 atcctgaatt gagacctggg tatttgacaa ggaaggatgg tagtttgctg agctggctat
    23041 tgaccaaacg ttccacacgg cgttcagaaa catttccaat ttcagaaatg gcaataccta
    23101 agaagtcaaa tggctgtgcc attggttctc cgtggaagtt acctcctgaa ataacgtggc
    23161 catctttaca gataattgga ttatctgtga cagaattgat ttcaatgtca actttggatt
    23221 tgacataggc gatactgtct ttgctagctc catgaatttg aggaatgcag cgcaaggtgt
    23281 aagggtcttg cacacgagat tgagtagcta cggttgtgtt ttggctacct tctaggaggt
    23341 ttctgatatt gcgggctgtt gccaactggc cactttgagg gcgaatggtg tgaagatttt
    23401 cttcaaatgg actagtgatt ccgttatgca cttcaaggga aagggcaccc gctaggtctg
    23461 acagtttcaa taattgaatg gcgtcatagg ttgcaagggc accgattgca gtgagaacag
    23521 ttgttccgtt gataagggcg agtccttctt tagcggctaa aggaatcttg tcaataccag
    23581 ctttatcaag agcttcttga ccagaaagaa gctctccttt gtagtaagct ttccctagac
    23641 caagcatagg aagcaccatg tgagcaagcg gcgccaaatc tcctgaagcc cctagagacc
    23701 ctttttcagg aatgtaagga tgaacccctt tattgagcag ttccaacagc ttttcaatgg
    23761 tggatagacg aataccagaa taccctttga cgagagagtt gatacggatc agcatgatag
    23821 ctctcacggc atcttctggc aatgggtcac caaatccact agcatgggta cgaatcaaat
    23881 tttcttggag ttgaactgta tcttctggtg agatgcttac gttacaaagg gatccaaaac
    23941 cggtggtcac cccgtaaacc acccgttttt cactgacaat gtcatcaaca attttacgag
    24001 aggcattcac agcttcaata gcactatcat caatgcgaca ggctacgcct tggcgagcaa
    24061 tcgcaatcac gtcttcgata gtaaggcttt cgccatctaa attaatcact cttgtcatag
    24121 tttttctcct agatttgttc cttagggggc atttggtcca tttggtggtt acgtccgtgc
    24181 ataaggtagt acacactact tgcaatgatg acaccaactg caccataaac aaagttcatt
    24241 gggttgtcac cccaaatcat aactaaacta acgataactg caagaattgg gataataggg
    24301 ccaaatggta ctcggaagat cacattagca tcgggatcgt ccttccgtaa tttcataacg
    24361 gctagtgctg ttggaatgta ttggaagaag cggaaaacaa cactgagttt tgctaagttt
    24421 tcaaatgagc cagtgagtag gagtacaata gcaattgctc ctgaaaccaa gatagcaacg
    24481 agtggtgcgc cattttgatt ttgcttggca atagcagctg gtaagagccc ttcatcagca
    24541 atggcagcac cgtaacgtgg caccatgatg gattctccca tgttaagacc tgtaatggaa
    24601 attaaagcac cgattgagac catccaagcg ccagcagggc ctatcatttt aacaaaggca
    24661 tcttgaacag gtgcattggt catcatgatt tgagagccaa gcatggcaat ggttccaccg
    24721 ataatcagca tatataagac agagacgata ctgattgatc ctaaaagagc acgcggtaca
    24781 tttttttcag ggtcacgcat ttccccagcg acaatagaga gggtttcaaa accgataaag
    24841 ccatagaaga tataaacagc agtattggag atagccccta agaggttagt ccctggttcc
    24901 aactgaacaa atggggtaaa gttaggaagc ccgtttttga tgaagaaaag ggtacaggca
    24961 caaaaggcaa cgattggaat taacttagca atggtggctg tgatggtgac aattttagag
    25021 gttttcaaac cagcgatatt catcaaagat agtaagatga ttaacccaat gctaagtgga
    25081 atgtgccaac cttcaaaggc agggaaagta atgataaaca ttctggcaaa cccagctgcc
    25141 atggctgccc aagcgaagat ggtaacggtc caaccaagga agccaacgtt aaagccaata
    25201 aaatcaccaa aagctcgttt ggaatattgg aaggctccgc cgtttttccc aaaataacca
    25261 gagacttctg caaaacaaac tgccaacatg atggtcaaaa tagctgttcc aaacataaca
    25321 gcgatggatg cagggccaag gcccttgtaa atggccctag gtaagagaaa aataccagag
    25381 ccgataacgg cattgatccc gtaaagagtg gcaccactca agctaaactt tgcctgttct
    25441 ctttcttgtt cgttcatgtg atttgacgcc ataataatgc tctccttttt gtttgcaaat
    25501 tgcgttcaaa tataatggat aaggtcgcta ggaaatgagg agatagtcgg tttaggaggg
    25561 tccttcttgc acctaacgat agtgatgagc tattggttag cgatgagaaa taggtagcct
    25621 tttgtgatga tgtgtagtga tttcattgga gaagaatagg catgagtagt gtgatgccta
    25681 tctttatccc actaagtctt ataccataag cctgcccaaa cagctactgg agtttgggcg
    25741 gggcttgttt gattgaggca aacttttaga tctgaaaggc tggcctcctg ctcgattacc
    25801 aacaagtgat tggcttcaag ttcttgattc gcctgattgg tcacagaata agtcagtttg
    25861 cttagggcat aaagcagttg acagtccgct ttaggtgcct caaatagtgt gtcagaccag
    25921 acgggtaata attgcccttg gtattggtca tcatacatta aattcatgtc ttggcagatt
    25981 ccacgactga cgattctggt atcgccttca aacgcataag gttcaaaagg agttagggaa
    26041 atctctttag catgactcaa atcactcaat gtgatgggct tgtctagggt cattagaatc
    26101 ctgtgatagc catcaagtaa ggtaaaggtt gtctgtcgta gggccacagt tgactttgag
    26161 aggcgataag agaattctct ctttttgtaa tctccatctt cgggataaag gaacaattgg
    26221 ttggtttcac cgccagacca gtcagtttgg aggtaatcag agggcgcttt gatagttacc
    26281 tttgtcattt gttctctcct tgtttccaat tagaatagtc ctgtgatgtt gccctcctcg
    26341 tcaatatcaa tggtttcgct ggcaggtact tttggaaggc caggcatggt catgatagca
    26401 cccgtcagag caacgataaa tcctgctcct gcagacactt tgaggttgct aatagtcact
    26461 gtaaagtcag ttggtgcgcc aagttttttg gcatcgtctg agaaggaata ttgggttttg
    26521 gccatgcaaa ttgggtagtt gccaaagccg aggcgttcta agtcagccag ttcacgtttg
    26581 gctgctgggc tcaagttgat gcctttacca ccgtaaactt tggtaacgat tttagtcagt
    26641 ttggtttcaa tgctatcgtc ttcctcataa acaaagcgga attgattgtc ttgctcagct
    26701 agtgtcacga ctttttcagc cagttcacgg ccaccagctc cgccatttgc ccaaacatca
    26761 gaaatcacaa cgtcaacgcc acgtttgtcg caggcatcat agacagcttg taattcggca
    26821 tcggtatcaa gcgggaattt attgatcgcc acgacaactg gaaggccata gacgtcttgg
    26881 atattagcca aatgtttgtc aaggttaggt aaaccatcca caacggcctg aacattttca
    26941 gtagccaggt ctgcttttgg cacaccccca tgcattttaa gggcacgaat agtggctact
    27001 aggacaacgg ctgctggacg aaggcctgac atgcggcatt tgatgtcaat gaatttttca
    27061 gctccaaggt cagcaccaaa tccagcttcg gtaacggcat aatcaccata tttcaaggct
    27121 agtttggtgg ctaggacact attacagcca tgggcgatat tagcaaatgg gccaccgtga
    27181 atgagggctg gtgtgtgttc cagggtttgc acgagattag gatgaatcgc atccttgagc
    27241 agtgcggcta gggcaccacc agctttcaag tctttagctg ttacaggttc gcctcgatag
    27301 ttgtaaccga tgatgatttt ttcaaggcgg gctttgaggt cagaaatatt ttcggatagg
    27361 cacaggattg ccatgatttc agaggcgacg gtaatgtcgt aaccatcctc acgaggggcc
    27421 ccgttgacct tgccttgcaa gccgtcaaca atatgacgaa gctggcggtc attcatatcc
    27481 accacacgtt tccaagtaat acgtctggaa tcaatgccta ggctattgcc atggtgaatg
    27541 tggttatcaa tcaaggcagc taataagttg ttggcgacac cgatggcatg aaagtcccct
    27601 gtaaagtgaa ggttgatgtc ttccattggg acaacttgcg cgtggccacc gccagcagct
    27661 cctcccttaa ccccaaaaac aggaccaaga gaaggttcac gaagggcaat aactgctttt
    27721 tttccaatgg cagaaagagc atctaccaat ccaacggaag tggtggtttt gccttcacca
    27781 gctggtgttg gtgagatagc agtgacaaga atgagtttgc catcaggttt gtcttttaag
    27841 gcgaccagtt gacgggcatt aatttttgcc ttgtacttac catagagaca gagcgcttcc
    27901 ttgtcgatcc ctaattgatc gccaacctta ctgataggtt ccatagagac agagttggct
    27961 atttcaatat ctgataaaac catagttgct cctttacttg ttaaacaata tcgagaattt
    28021 tcgtgtagat gtcatctgcc aagtgacagc ccttgtctaa taaggcttgt cctttttggc
    28081 gatagtcggt aacaaagtct tcatctttga tgccagacag attaatcaaa acattcaacc
    28141 aagcgccttg taaacctgct tttaagttta aagcagcaac tcctaagtcg ctagcagcat
    28201 ttgtattaga cttaccgaca gctgttgcag tgatctcaag tgcttcgacc atgagggtca
    28261 tcatctcaaa aggtgattgt gcagctgttt tcaaggcctt ttgcatggca gttcgtctag
    28321 cagccctgtc ttcgtcagtc tcttttggca tatcaaaaac ggcagaaacc aggttgaagg
    28381 cttcggtgtc tttgtcaatg gcatctaata agtcctgttg caagcgacta cttttggtat
    28441 gaaggtcttc aatgataact tgataatcag catacttttt cttaccaaga gtcaattcac
    28501 agaccatctt ggttaaggaa atgccgttgg cacctgatag tgcagcagca gaaccaccac
    28561 ctggagcagg ggcatctgag ccaaggactt tagcgaaatc tgttaagctt aaatcaacta
    28621 aacccataga gaacctccta acctagcaaa tggttttcaa gaacctgttt attgtagtca
    28681 aagtcctcaa cttgtaagta gtattcagcc acatcgatta aggccttggc tggcgctaag
    28741 ccgatgactt cagaaccaat aacattcaca ccgtagcgac gcgcttcaaa tttgatggtt
    28801 tcaaaagtac ggtaaagaga acatttttca aagttaacca tgttcatgga gacttgggca
    28861 atatgacggt cttctaacat gacaccgata gccttacaat atttgtagcc accacctgaa
    28921 ccgcggataa ttttcgcaat tttatgagca atgtcgatat tgtcagtatc caaattaaca
    28981 ttgaaggcaa ccaatggcat gcgagcacca acggcagtta ccccagcagt tgggtgaatc
    29041 ttacgatctc cgtagtcagg tgcccaatcc tcttccaaca gtttttctgg catgccttcg
    29101 aattgtcctt tacggacttt ggccaggttt tgacgttctg ggcgtgtggc agaatcttca
    29161 taaaggaaga ttgggattcc aagtttacgg ttaatccgtt ctgcgacttg tttggaaatc
    29221 tcaacacatt cttgtgtagt gatgtctttg atcggaacga atgggcagac atcggttgct
    29281 cccatacgag ggtgttcgcc atgatgtttg gtcatatcaa tgttttcaga agcgtatttc
    29341 accagttgga aagctgcttc ttgaatagac tggtcatctc caaccaaggt aaacacgctc
    29401 cggttgtggc tcgcatcaga agagtagtcg agaagggtca ctccaggaat acttttggcc
    29461 gtcgctacca aaccatcgat aacagcctga ttttggcctt ctgagaagtt gggaatacat
    29521 tcaacaattt tcgccatgtt taatctcctt ttatgtcatt gagttactca ttaagggaat
    29581 aggttaccta ctttagataa cgcttacatt tttagctagc agtcattagt gaaataattg
    29641 atctaccgct gaagtcacaa ggtcatcgtc agccaaatat gggatagtga tatgatcagt
    29701 acctgcatgg agacggttgt attcaatagc ggtttcaata gcgtgctcat tgcgagccca
    29761 attgcgacga gcaacaccac ccatggtgtc ccaagcaata gcagatttaa taatctcatc
    29821 aatgcgttcg ctgccatcta aaacaagtcc gaaaccacca ttgatggctt taccaatacc
    29881 agttccgcca ccgttatgaa gagccactaa actcatacca cgcgcagcgt taccagcgta
    29941 acattgcacc gccatatcac aggtcacatt ggaaccgtct ttaatgtttg aggtttcacg
    30001 aaatggtgag tcggtaccag acacgtcatg gtggtcacga ccaatcatga caggaccaat
    30061 cttgcctttg cggaccaatt cattaaattt aagggcgata gtcacacgac cgatacagtc
    30121 ttggtaaagg atccgggctt gggtaccaac tacgagttga tttttctcag catcacgaat
    30181 ccagttgtag ttatcacggt cttgatagcg gcggtcagga tcgatagctt ccatggcagc
    30241 tttgtcagtg gccaccaagt catcgtgatt accactcaag cagacccaac ggaaaggtcc
    30301 atagccatag tcaaaaagca taggtcccat gatatcttcc acataggatg gccagataaa
    30361 tccgtctttg tcgttacgac cattcttaga aatttctgta ataccagagt cgtaaacaga
    30421 cttcataaag gcattgccgt agtcaaagaa ataggtgcca ttttcagtta acgtcttaat
    30481 agcttcaaaa tgccgtgcca aggtatcatc aaccatttgg tggaaggtat ctttatcttc
    30541 tgccaagagc cgggttcttt cgtcaaagct aatacctact gggcagtagc caccgtcata
    30601 aacgttgtga caagaggttt ggtcagacaa aagatcaaca tgaatctgct tgtcattgac
    30661 gtactctaaa agatcaacga tattaccatg gtaagcaatc gaagtggact ctttagcatc
    30721 tatggctttt tgggctaatt gcagagcttc ttcagggctc tcagcaattt ggctaaccca
    30781 gccttgcgaa tgacgggttt caatccgaga ttggtcaact tcagcaataa tggcaactgc
    30841 tttagcaatt tcagcagcct taccttgtgc cccactcatg cctcctaaac cagatgagat
    30901 aaagagttta ccggtcaaat caccgtcatc agccactcca agtttgagac gaccagcatt
    30961 taagagggta ttaaacgttc catgaacgat tccttgtggg ccaatataca tccaaccacc
    31021 tgcggtcatt tgaccatagt tggtgacacc catctcttca gcgatttccc agtctttcat
    31081 gttgtcgtat tcacccacca aaaggccatt agtaataatc acacgaggcg cttcaggttt
    31141 ggatttgaaa agaccaactg gatgaccaga ctcaaccacc aaggtttgtt catcagtcat
    31201 gacttctagg tattttttaa tcaaacaata ttgcatccag ttggcacaaa cagaaccagt
    31261 ttctccataa gtgactagtt cgtaagggta caaggcaatt tcaaaactca agttattgtc
    31321 aatcatgact tgcatggcct tggcagctgt acaatttccc ttgtactcgt taatgggttt
    31381 gccgtaaatg cggtcttttg gtctaaagcg gtagccataa atacggccac gggttttgag
    31441 ttcttccaaa aattctggaa tgacttcttc gtggaacttc gtaggtacat agcgtagggc
    31501 atttttcaag gcgatttcgg tctgagcctg ggtcaatcga aaacctctgt ctggtgctct
    31561 gcggatacct tctttgaaga cagtcttttc cggtaaaaca tcgtctaact taacagtcat
    31621 agcggcagct atgtcagttt cactgtaaaa tgacatagaa aactcctcct caactccttt
    31681 ttattgtcga gattagtcta acttagtcta gtctataaaa agtcaaccac gctttgaaat
    31741 gcgaaaaaag tctaaaaaaa aatcaaaacc tcattttttg actaaaattt gacgcttaat
    31801 cagtacactt gaggcatgac agataaagtc agtcagaggt taattgttgt taccaaagtt
    31861 gcaaagatcg caactattga gtgggtgagg ggggactagt aatggctatt aatcagttga
    31921 caaacgatgt taaaaaagga ggtttttatg gttgctgatg tcttattaac acattttaat
    31981 caactatttt gtctaaatga tccaggtcat cctttaactg gtcaagaaat gaaaaaagcc
    32041 actatcgttg aagatggcta tatagccatc aaagacggcc ttattgtggc tcttggttct
    32101 ggtgaaccag atgctgagct tgtcggtcca cagactatta tgcgttctta taaaggtaaa
    32161 attgcaacgc ctggtattat tgactgtcat acccatttgg tctatggtgg cagtcgggaa
    32221 catgaatttg ccaagaaatt agcaggggtg tcttacttgg atgttttagc tcaaggtggt
    32281 ggtattttaa gcacggtgag ggccactcgg tcagccagct ttgacaacct ttatcaaaaa
    32341 tccaagagat tgctagacta catgttgctt catggagtga ctactgtcga agcgaaaagt
    32401 ggctacggcc ttgattggga aacagaaaaa cgccaactgg atgttgttgc tgctttagaa
    32461 aaagaccatc ctattgattt ggtgtctacg tttatggcag cccatgcgat tcctgaagaa
    32521 tacaagggga atcctaaggc ttacctcgat gtgattgttg agcagatgtt gccagaagtt
    32581 aagaaagaga atctggcaga attttgtgat attttctgtg aaaaaaatgt ttttacagct
    32641 gatgagtccc gctatctgtt aagcaaagcc aaagaaatgg gcttcaagct tcgtattcat
    32701 gcagatgaaa ttgcgtctat cggcggagtt gatgtcgcag cagagctcag cgcagttagt
    32761 gcagagcatt tgatgatgat aacagatgat ggtatcgcta agttgattgg tgctggtgtt
    32821 attggtaatt tgcttccagc caccaccttt agtttaatgg aagacactta tgcccctgct
    32881 cgcaaaatga tcgatgccgg catggctatc actctctcaa cagatagtaa tccaggcagt
    32941 tgcccgactg ctaacatgca gtttgtgatg caattaggtt gttttatgtt acgtttaaca
    33001 ccgattgaag tcttaaatgc tgttactatt aatgcggcct actctgtcaa tcgtcaggag
    33061 agggttggta gtttgacagt tggtaaagaa gcagatattg ccatctttga tgccccaaat
    33121 attgattacc cattttattt ctttgccacc aacttgattc accaagtcta taaaaaagga
    33181 caactcacgg ttgatcgagg tcgtattctt taaaaaattt caaaaagaag ctttgagcgt
    33241 tagctcaaaa cttcttttaa atatgctatt ttattgacga atcaagtagt caaaggcacc
    33301 gatggcagca gtagcaccag accccatgga aataatgatt tgtttataag ctgaatcagt
    33361 acagtcccca gcagcaaaga tgccgggaat attggttgaa ccatgtttat ccacaatgat
    33421 ttctccgcgg tcggttaggt tgacaccact atctttgagc caagctgtgt ttggaacaag
    33481 accaatttga acaaagaccc cttcaaggtc aaggtgtttg tcttcaccac tatcacgttc
    33541 agtgtagttg agacctgtaa catggtcctc tccaacaatg tccttagtaa caacattttt
    33601 gatgatggtc atattgttag tcttagctgc gcggtcttga agcactttgt cagctttaag
    33661 ttcaggtaag aattctaaaa cgtaaacgtg tttagcaaga ccagccaaat caagggccgc
    33721 ttctaaaccg gagttaccac caccgataac ggcaacatct ttgccttcaa agagtgggcc
    33781 atcacaatga ggacagtaag tcactccttt gttacggaat tcatcttcac caggaacatt
    33841 aatgttacgc catttggccc caagagctaa gatagcagtt ttggcttgta aaaccgcacc
    33901 attagctaga gtaacctcga tgttttcttt tttctcaata gaagtagcta gttgtgcttt
    33961 gataatatca acatcataag acttagtatg ggcctccact tcggccatta attttggtcc
    34021 ttcagtgtaa agggtaccaa tcatgttttc gatgccgacc gtttccatga cctgaccacc
    34081 aaaggtttca gcaagtaaac ctgtttttag tcctttacga gctgcataga tagcagcgct
    34141 attgcccgca gggccaccac caataacaag gacatcatag agtcctttat cagcaaaggc
    34201 ttcctcagaa agtgggccag cgatttgttc taagagttgc tcaatggtag cacgaccaga
    34261 agtgaattct tccccgtcta aaaagacagt agggacagac ataatgcctt tggctttcac
    34321 ttcatcttgg aacatgccgc cttctaccat agtgtgtgaa atcttgtcgt tcaagacgga
    34381 cataatgttt aaagcttgaa caacatctgg gcagttatgg caggttaagc tgacataagt
    34441 ttcaaaatgc aacggacggt caatggcctt gatgcgatca ataacatctt gatccacttt
    34501 tggagcacgt ccagatactt gcaagagagc aagaataaag gacgtcaatt cgtggcctaa
    34561 aggaagacca gcaaagacaa ccccactatc gtgacctttt ttcgcaacct taaagcttgg
    34621 ttgtcggtct aaagtgatgt tttcaataga aatacgctca gacatagcag ctatttcttc
    34681 cacaaagtct ttgacttttt gagactgctc attgtcacca agggaaactt gcaaaacaag
    34741 atcagcttct aacagggtga ggtattgggc aagttgttct ttaatatcag gacttaatgc
    34801 catagctttc ctcctaaaat ttattaaatt ttaccaacta aatcaagact tggtgtcaaa
    34861 gtttcagcgc cttctttcca tttagctgga caaacttcac ctggatgttt acggacgtat
    34921 tgggcagcgt gaattttatc aatcaaggtg ctagcgtcac gtccaatacc atcagcatta
    34981 atttccatca tttggataat accatctggg tcaacgataa atgttccacg ttgagcaagt
    35041 ccgtcttcgc caagcacttc aaaggcttgt gaaataaggt gtgaagggtc accaatcata
    35101 gggtatgtga tagtgccaac cacatctgag tcatcatgcc aagctttatg aacaaaatga
    35161 gtatcagtag agacagaata aacttctaca ccaagagatt tcagtgtttc gtattgctct
    35221 tgaaggtcac cgagttcagt tgggcaaaca aatgaaaagt ctgctgggta gaaacaaaaa
    35281 actgcccatt ttcctttaac gtcttcattt gtaacagtga tgaattttcc atcatgataa
    35341 gcttgagctg aaaattcagc aatttctttt ccaattagag acatatagtt gtcctccttt
    35401 tttatagttt tatacttgta ttataaaaga acaacaagat tatgtctact cagaaaccct
    35461 tgattttact gggaaatcag cgattgtttt ctgacaattc agttgtgaaa taaatcacat
    35521 taattaaaat gattctaaat aagctgaaga cgccgttaaa tcaaaggtta atttaattat
    35581 aatatacaga aaatataatt gttattaaag cgtttacaaa aaaacttttt tgattccgtt
    35641 aaggcaactt aatattatgg ttacctaatc actaatattg taacctattt tggcatgaga
    35701 tcagggaatg gctgttatat taattggata tgtcttgtgc aaatagtgct tgacggattt
    35761 gtggaattag ggtaaaataa tctttgttgt ggcggtatag ccaagtggta aggcacggct
    35821 ctgcaaaagc ttgatcgtcg gttcaaatcc gtctaccgcc ttttatatac aaaacaagcc
    35881 ttgattaact tcgtgaaaac gttgttaaat caaggttttt attttttgcg acaggataaa
    35941 aaaagagaaa aaaagaaata aagtcggtca aatttcccga agatgtcttt tatagcctga
    36001 ttattaggta tgaaaaatac tatggccaaa attggtaaac gattgcaaat aaaggtcaga
    36061 gttcttaccc ccttaaacga tatgcgttaa aagttagttg aactgccgtg caccttaacg
    36121 atagacacgg tgatgtgaga gcaagtagag ttgaatctct actcgcttat cttaccatag
    36181 tcagctttat aaagtaacca cccattacaa tgcaactata ttcttaatgt ttttaagcat
    36241 gttattgaca agtgttataa aatgtgttac ccttagtgag taaattagtt tttgagttag
    36301 tatttgtgtt tcaacatctt tatttctctc tatttttaca aatgattttt agaaaggaag
    36361 tggatgtata tggcacaagg tacagtaaaa tggtttaacg ctgaaaaagg ttttggtttt
    36421 atttcaactg aaaacggtca agatgtcttt gcacattttt cagcaatcca aactaatggt
    36481 tttaaaacgt tagaagaagg acaaaaagtg gcatttgacg tcgaagaagg tcaacgtgga
    36541 cctcaagcag tcaatatcac taaattggcc taatctggtt aaagtaacta aagggaagca
    36601 gatgttggaa acaacaactg cttttttgat ttctaccagt tacctttaat gattaagagt
    36661 tgcgtttaag gtcttgtatt tgttataata atagtcagtt ttagtcaaaa tgtattgacg
    36721 tggtgctact aagtttttag agtagcccgc aagcaaagga gtgacagcat gccaaccaaa
    36781 aatacttcag acagcattga agagtatatt aaagaattat tagctaagtc aggaatagca
    36841 gaaattaagc ggtccatgct agcagattcg tttcaagttg tcccaagtca gatcaactat
    36901 gtcattaaaa cccgttttac ggagagtcga ggctatgaag tagagagtaa acgaggtggt
    36961 ggaggctata ttcgtattgc caaggttcat ttttcagaca aacaccatct gattggcaat
    37021 ttaatggcaa ctattgaaga atgtatcagt gagcaagttt tcacggactc gatacaattg
    37081 ctttttgacg aacacttatt gacagagcgt gagggaaata tcattttggc tgtggcgtct
    37141 gatgatgttt taggaactga tggttcaact attcgtgcac gaatgctcta tcgcttattg
    37201 caacgaattg acagaaaggg aagcaattaa tgattatgta ttcaacgaag atgcaagaca
    37261 tttttagaca ggcgcagttc caagctgctc gctttgatag ccattgcctg gaaacttggc
    37321 atgttttgtt agctatggta gctgtagata attctttagc aaatatgatt ttaagtgaat
    37381 atgatgccca agtcgccata gaagaatatg aagctgcagc tattttagcc atgggcaaaa
    37441 cccctaaaga acagttgtct cgtgtagact tcagacctca atctaaaacc ttgactaact
    37501 tgttagcttt tgcgcaggct attagccaaa tcactaggga tcaagaagtc ggctctgagc
    37561 atgtcttatt tgctatttta ttgaatccag atattatggc gagtcgtttg ttagaaatag
    37621 caggctatca gataaaagat aacggcaatg ggcagccgcg attagctgac ttgcgaaaag
    37681 caatagaacg tcatgcaggt tacagtaagg aaatgatcaa ggctattcac gaactacgta
    37741 agcctaaaaa aacgaaaaca caagggacct tttcagatat gatgaagcca ccaagtacag
    37801 ctggtgagtt gagtgatttc acaagagatt tgactgaaat ggcaagacaa ggtttgttag
    37861 aatcggtgat tggacgtgac caagaagtat ctcgtatgat tcaggtacta agtcgtaaaa
    37921 cgaaaaacaa tcctgtcttg gtaggtgatg caggtgttgg taaaactgcg cttgcttatg
    37981 gccttgctca acggattgca aatggcgcta ttccttatga acttaaggag atgcgtgtcc
    38041 tagaattaga catgatgagt gtggtagcag gaacccgttt tcgtggggat tttgaagagc
    38101 gcatgaatca aatcattgat gatattgaag ctgatggtca gattattctt tttgttgatg
    38161 aactacatac tattatgggt tctggcagtg gtattgacag tacacttgat gcggctaaca
    38221 ttttaaaacc agcattatcg cgcggcactc ttcatatggt tggagcaaca actcaagaag
    38281 aataccaaaa acatattgaa aaagatgcag ctctttcgcg tcgttttgct aaaatattaa
    38341 ttgaagaacc taatacagaa gatgcttatc agattttgat gggcctaaaa ttatcttatg
    38401 agacctacca taatgtctcg atatcaaatg aggcagttaa aacagctgta aaaatggcac
    38461 accgttattt aaccagtaaa aatctccctg attcagctat cgatttatta gatgaagcta
    38521 gtgctgctgt gcaaaacatg gtgaaaaaat cagcacctga gactttaaca ccaatagacc
    38581 aagctcttat caatggtgat atgaaaaaag tatctcgcct cttagctaaa aaagcaaaag
    38641 gtcagatgag aaacccaaca ccggtgacag aagatgatat tttggcaacc ttgagtaagt
    38701 tatcgggaat tccacttgaa aaactgacgc aagctgatag taaaaaatac ctcaatttag
    38761 aaaaagaact gcataagcgt gtgattggtc aggatgctgc tgttacggct atttcaagag
    38821 ccattcgtcg taatcagtca ggtattcgaa caggaaaacg tcctattgga tcatttatgt
    38881 ttcttggccc aacaggagta ggtaagacag aactagcaaa ggcccttgca gaagttctct
    38941 ttgatgatga agcagcgctt attcgttttg atatgtctga gtacatggaa aaattcgcag
    39001 cgtctaggct taatggagca cctcctggtt atgtcggcta tgatgaagga ggtgaactga
    39061 cacagaaagt tagaaataaa ccttattcag tcttgctttt tgatgaagtg gaaaaagcac
    39121 atcctgatat ttttaacgtt ctccttcaag tattagatga tggtatattg actgatagtc
    39181 gtgggcgtaa ggtcgatttt tcaaatacta ttattatcat gaccagcaat cttggcgcaa
    39241 cagccctgcg cgatgataaa acggtcggtt ttggggtcaa aggcattcac caagaccatc
    39301 aagctatgga gaaacgtatt ttagaagaat taagaaaaac ttaccgccca gaatttatca
    39361 atcgtattga tgaaaaagtg gtctttcata gtctgaccca agataacatg cgcgatgtgg
    39421 ttaaaatcat ggtacagccc ctgattacta cattggcaga aaaaggtatt acccttaaaa
    39481 ttcagccttt ggccttgaaa catttgtccg aggtcggcta tgatgagcat atgggggcaa
    39541 gaccattacg tcgaacgctg caaactgaga tagaagataa gctatcagag cttattcttt
    39601 ctcgagaatt gacaagtggg catacgctaa aaattggatt atcacatggc aaattaacgt
    39661 ttcacatagc ttaatttcca tataaaaggt ggatcatcct tgatgtcacc aaaaaaagag
    39721 gttattctta caaaaataac ttcttttttc ttgactattt ttgaccaagt gataaaatag
    39781 aatataaagt tagcactcga tgaacatgag tgctaacttt actaaagatt cttttattgg
    39841 aggaaaattt catgttaaaa ccattaggtg accgtgtggt cgtaagattt gatgatgaaa
    39901 aagagcagac agtcggtggt tttgtccttg caggcactca taaagagtca acacgaaaag
    39961 cgacagtcct cgctgtcagt gaaacgggtg ttcgcactat tacaggtgat agcgtgctac
    40021 cttcagtttc agtgggtcaa gaggttttag ttgaaaatgg gcatgattta gaagtaaccg
    40081 tagatgatga gaaagtttct atcatccgtg aatctgacat cattgctatt gttacaaaat
    40141 aaaacgacaa atctctaaat agaaagaagg attgaatatg gcaaaagata ttaaattttc
    40201 agcagatgcg cgtgctgcca tggtgcgcgg agttgatatg ttagcagata ccgtcaaagt
    40261 aacgcttggt cctaaagggc gcaatgttgt tcttgaaaaa gcttttggtt ctcccttaat
    40321 tactaatgac ggggtaacca ttgctaaaga gatcgaatta gaagatcatt ttgaaaacat
    40381 gggagcaaaa ttggtgtctg aagtggcttc taaaaccaat gatattgctg gtgatgggac
    40441 gactactgca acagttttga cacaagccat tgttcatgaa ggactaaaaa atgtgacagc
    40501 aggtgctaat ccaattggta tccgtcgagg cattgaaaca gcaacagcaa cagctgttga
    40561 agccttgaaa gccattgctc aacctgtatc tggcaaggaa gctattgctc aggtcgctgc
    40621 agtatcatca cgctctgaaa aagttggaga gtatatctca gaagctatgg agcgtgtggg
    40681 caacgatggt gtgattacca tcgaagaatc tcgaggtatg gaaacagaac ttgaagtggt
    40741 tgaaggcatg caatttgacc gtggttacct gtctcaatac atggtcacag acaatgaaaa
    40801 aatggttgca gaccttgaaa acccatttat cttgatcacg gataaaaaag tgtcaaacat
    40861 ccaagacatt ttgccactac ttgaggaagt tcttaaaacc aaccgtccat tactcattat
    40921 tgcagatgat gtggatggtg aagcccttcc aacccttgtc ttgaacaaga ttcgtggtac
    40981 tttcaatgtg gttgctgtca aagcgccagg atttggtgat cgccgtaaag ctatgcttga
    41041 agacattgct atcttgacag gtggtacagt gattacagag gatctaggac ttgaattaaa
    41101 agatgctaca atgacagccc ttggacaggc tgctaagatt acagttgata aagatagcac
    41161 agtaattgtt gaaggttcag gaagttcaga agctattgct aaccgtattg cactgattaa
    41221 atcgcaatta gaaacaacaa cttctgactt tgaccgtgaa aaactacaag aacgtttggc
    41281 gaaattagct ggtggtgtag ctgttatcaa agtaggagct ccaacagaga cagctttaaa
    41341 agaaatgaaa cttcgcattg aggatgctct aaatgccaca cgtgcagccg ttgaagaagg
    41401 tatcgttgct ggtggtggaa cagcacttat tacggtgatc gaaaaagtag ctgctcttga
    41461 gcttgagggc gatgacgcta ctggacgtaa cattgtgctt cgtgctctag aagagcctgt
    41521 acgtcaaatt gctttaaatg ctgggtacga aggctccgta gttattgaca agttgaaaaa
    41581 cagccctgca ggaacaggat ttaatgctgc aacaggtgag tgggttgata tgattaaaac
    41641 aggaatcatt gaccctgtca aagtaacacg atcagcgctt caaaatgcag cttctgtagc
    41701 tagtcttatt ttgacaacag aagcagttgt tgctaataag cctgaaccag ctgcgccagc
    41761 gccagcaatg ccagcaggta tggatccagg aatgatgggc ggcttctaag ctctctatag
    41821 cattaaggat tatgaaaaag aagttgagac taaaggtctg cttcttacta tgaaaaaaga
    41881 acaaagattg gatttcgact catgatatcc catctttgtt tttttagttg tgatataaaa
    41941 tgctaatctt tgtggttaca gacttttaat gtattggaaa atacattgtt tttctttgtc
    42001 atgtgctatc atggagtcaa tgaaaagtta ttcccatata tgggtgttgg agggaaattt
    42061 tggagagatt tttaaaacct ttagagaatc aaagggatta cgattaaaag atgtcgcaaa
    42121 ggctggtgta tcaacctctc agctgtcgcg tttcgaaaaa ggggagacgg acttaaccat
    42181 atcgacattt atgctgattt tggatgaaag taacatgccc attaatgagt ttatgtatgc
    42241 tgtccatgat tttcatcgtg acgacttaaa tgaactctta tcaaaaagtg aggcatttcg
    42301 taacaactca agatagtgat ggcttgaagc agttacttca tgctcaacta gcatcaactg
    42361 ataagaagga gatgttcacg gatatctttt ggcatatcca gcatgtctaa gtctgctatg
    42421 gcatgctatt ttgggagtcc ctcacgcgac tctgtcagta gctctccttc aaaggattca
    42481 catagaaagt cgtaatagac atagcagtca ggcttgataa agctagaaat actctttaat
    42541 tgaaggttta aagctgtcag acctatctct tcttttagtt ctcataaagc cgcttcaaag
    42601 aaagattcac agggctcgac tttaccttct ggctggatcc atcctgggaa gttatcgtgt
    42661 tgtctatgga gtcataaaat catatcgtta tgtttgacac aaatattctc ccagtcttta
    42721 accgttgcta tcaccagatt caccaccttt tagtatagta taagaaaaaa ggggtaaaag
    42781 aggtttcttg ttgttttttt ggcttaaggt ttctttaagt cttatctagt atactaatgt
    42841 cattccttaa taggataagt atttggttgt agaagtatcg tcttaaacta acgctatctc
    42901 aacccgattc ccatcttatt cacccctcct ataccgataa ggtctcacaa agtgtgagac
    42961 cttatttttt gacttcagct ctagttatgg agaaacttgt tgatacaagc ttttttgggt
    43021 tatggtatta tgatctattc aagcctttct tgtttttggg tttttcttta accaacttgg
    43081 cttcaatagc ttttaagcgt ttgaaggttt tttcagcgcg atctagtgaa atcttatcag
    43141 ctttttcttg agcagctttg aggtcactga cgactaagtc actgatttct ttggtgcttt
    43201 tgtcttgttc ggctatccag gttttttcca agcctttcat ctcatcaatc actttagttc
    43261 caaatggttt tggatgagca gccacgagat cattaatgtg tgacaccgtc caataccatg
    43321 acttatcgtt atattgggtg cttttttctt gataggcttc ataggttcta ctgatattgc
    43381 caaggtatgg caagtaaggg gcattacgag gactgccaat agatagccac atgacaccac
    43441 cacccaattc agcagggatg tcttttttca gttggaaaat atgagcttcc atgacattag
    43501 gatttgagat gggataagca tagcccttaa cagctttttt ggattttggt ttacccttac
    43561 cgtctaatgc catctgatca agtggtttaa gatccagacc ctcaaaacga ttacgttgca
    43621 gtttcatcgc atcttctaga ctaaaggtct tatcagtgct ttggagcaac tcataattgc
    43681 tgtctttata agttactttt gaatcagggt caagtgattt aatccctgag aaagagcgag
    43741 agcggttggc atcgtttagt ggtggattgt aagatttggc aatatgaaat ttaccatcaa
    43801 cttcggtata agatttggct tttttagcga ctttttccac atcttctgag gcaatcgtat
    43861 tttccttatc gttgaaatcg acatgtccaa gatagaaggt atttggaaaa acagcgtatt
    43921 tatcatctgg gaatttgatg gcaacgtatt ggtgaccaga gagaatttcc atgtaccaga
    43981 tgccgtcttt gtcagccaag gtaacaatat ttccttcagc agctcctttt tcagtgacta
    44041 ttttagcaat caatgcgaca ccttcacggg ctgttttgac acttggtaaa atgacactgg
    44101 ccatagatga ttccgctaag ccatttttga cgtaaggatc aattttttgg atggcatcat
    44161 tagctgaagc tgatactgtt gcagacatag agacgccaaa ctcattaaaa ccagcttcgt
    44221 cataaacgcc tttgttaggt gttacatcag gaatcgcact atagcgataa gaatgctcag
    44281 gcaacgggta ctcaaaacca ttagagaggt ctttccattt ttggccagca ggattgtcct
    44341 ttgctagacg tacaatgaaa tttttattat ggtgtggctc aagatcttct gttcgaccat
    44401 aaagaagaga accgtctttg gttaaatctt tgccaataat aaaaccagta caagcataac
    44461 taacactttg aagcgaaaag gctgtcagaa tacttaaaac tccaagtgat atttttttgt
    44521 ttatcatgcg aatcctccta gtaaacgata acgctttcac agacattata aaatgctctt
    44581 tttaaaaatt caagtctttt atgaagtgtt ttgaaattgt tagctatcta aatattatga
    44641 gaattctctc ttgaattttg gcttaacggc ccctaaaaac gtataggcag tgaactatct
    44701 aggtttcttc gaaaatccat tagccattta tgatataata gtaaagaaaa acatagaaag
    44761 ttggggtctg ttgatgacca aaccatttca tcataagaaa ctaaaacaaa taactataat
    44821 agctgcaact agcctttttt tattcctgat cggtggtgcc ttttactact ctaaaaatca
    44881 ttgtattaat gcctatctta aagctcgatc ggcccaatca ggaccagttt ttgagaatat
    44941 caaagcatat ctagtctggg atgatactaa tgagcagatc acaaatgacg aggcgatgta
    45001 tactaagttt agaaggtata gtcagaaaga attgaggcaa aaaaagcagg atttaaaagc
    45061 cgctagtcaa gatagtgccg ttcaagtaaa gtctgttggt cgtcgttttt ggatttttcc
    45121 tgattatcgg attgccataa aacccatgga tttaacgata aaaacgaatg tgcctcaagc
    45181 agacgttctt ttaaatcaaa aaaaagttgc tgtttctgat tcagaacagt tctcagtcaa
    45241 gcttgatcgg ctaccaacgg cagaatatac cgcaagtatc agaggcaaac acaacgggcg
    45301 aaacattaaa gtcaacaaat catatgatgg tgataatccc gtgctagatt tgagtgtgtc
    45361 ttttagaact tttttggtaa caagcaatgc taagcaagga gatctttact tcgatgataa
    45421 ccatattggc acattaaaag atggtcaatt acaagtagaa gattaccctg ttacagaaaa
    45481 cgcacaagct tatatgaaaa caacattccc agatggtgag ttaagatcac aaaaatatgc
    45541 tctagctgat gttgaagaag gagcaaccct ggagatttta gttacagatc ttttagaaga
    45601 ggacaaagca ggggagctat tagtatcagc ttttgatcag ctgatgcact acctcagtac
    45661 aggtcaagac tcatctaact tacgtagcgt ctttgaggca gggtctagca acgcatttta
    45721 taggggattg aaagagtcca taaaagcgaa atttcagaca gatacaagaa aagccagccg
    45781 tctcaatatt ccatctatcc ttttgacaac aatgactcaa gtgggcaaaa caacttacgt
    45841 gcttgatttc acagctacct acgaattttt gtatgacaac tcaacagatc ctgagcagca
    45901 tacctctgga catattaatc aagacttgac tggaaaagtg acggtaaaaa aagttggaca
    45961 gcattacctt atcagccagt ccggctccaa aaatattact gttgttaaag aggacaatca
    46021 actcaaagcg ccatctgtct ttcctgagtc tattttggga acgtggacag gccaagccaa
    46081 tggtttgagc atccatatgt ctctagcatc agatggaaca attacgacta aagttgaaga
    46141 tcaaaaaggc aaccgttcta aagaaactcg gacagctaaa attagtaaag ttgaagacaa
    46201 aggcaatggt ttttatcttt atacgccaga tcctggaagt gacataagcg ccttagctcc
    46261 agaaggagga ttggggggtg caaatgtcaa atatgcttat ggtttcaaaa tatctggtaa
    46321 aacagcctct ccagtggtgt ggcaggcagc attaacacat gaatttgatt ataccaagcc
    46381 actttcggga gtaactttgc aaaagcaacc ataaaggatg caaagccaca aagaacagta
    46441 gaaacaatgt tattactcaa atacagtgct atgaaaacag ctaaactcaa aaggctagga
    46501 gattatttcc tagccttttg agcgtttaag actgcgtcaa atgtagctga tttagcttgc
    46561 acgcaaatgt cttcttgggt tagagggtgt ttcaaacgta attgataagc atggagcatc
    46621 agtcgagcac aatctttctt tccattagaa tacaaaggat caccaaataa aacatgacct
    46681 tgatgggcta aatggactcg aatttgatga gtccgtccag tttgtaattg acaattgagt
    46741 aagcttgccg ttttgtggaa gtttttgact agagttacct cagtaatagc tttcttgcca
    46801 tttatcggat cgacaacacg ttttctgcgg tcatgtcgat gacgaccaat tggatgatgg
    46861 taagttaccc taggactgtc taaggatccg tgaactagtg ccaaatattc tcgatggatg
    46921 tctctttttt ctaaaagacg attaaggatt ggtaagataa aaggtgtttt agcaaataaa
    46981 atggccccac ttgtttcctt atccagacga tgaaccacat agcaggtctg tcccgtgtaa
    47041 gcagacacgt ggttgagcag cgccaactct gttggatcat tgccgtgtgt tttcatccct
    47101 tcaggtttgt taacaataat gatgtgctca tcttcataaa ggcaggttac tttttcggcc
    47161 tgccccatca cgataatctt ttcaggataa tcttcgtgat caaaaaaaag tttgacctga
    47221 tcaccgtatt taacacaact ttgccagtta acaggatgac cattaataag aacatgtttt
    47281 ttagttctca gaaaatgcct aattttacgg ggaattaaca attgttcctc taataatgct
    47341 ttgaccgtca attcttcaaa gggatttttc agtgtgacag taaacccctt tgatggttta
    47401 tttgttgtct tcattgagcc agttatggta tttttcaaca aggttgatag ccatttgggt
    47461 ggcaagagca gcagagaaag cttcagtacc ttcacgctcg tcattagcta cctccaagcg
    47521 agtctcatcg taaatggctt ttagactttc tgcggataag gtttctttaa aagcttggaa
    47581 tttattcatt ggttaaaccc gtccttctat gtttaatgtg agctcctgat taagcaagga
    47641 attcaatgct attatagcat gtttctaatc aaaacgtgcc actcaaaaag gtaaaaacgt
    47701 tattttgcta atccatataa taagaaagtg tcttaaataa gacctcttga tagagtttgt
    47761 aacaaaaatg atatgaaact aggtgctaac gcagaaatag aaaacaacta acgtgttgcg
    47821 aagttggagc agtcataaaa aatagcaaga taaaacttat caacacacag ttacctaaga
    47881 cgatgagtca aacaggtatg ttctttcaaa acaaccctat gaggttgaac gacgtatcgg
    47941 aaaaatacgg attagtttgg ccttatgata ggtatttctc tatcgtaaaa gaagtcaacc
    48001 aaaggttttt aatataaaat attaagaaaa attgttataa ttatgataaa aacataatcg
    48061 taaaatagag gaaaaacaat gaaaacaatt agacgttatg atgttaacga agatagaggg
    48121 catacaggcc ttgtagaagc aggagacttc tattatttaa actattgtgt cggcaatgtt
    48181 ggacaagaca ttgaaagtca gattaatgga gcctttgacg agatggagcg ccgattagca
    48241 ttggtggggc tcacattaga tgcagttgtt caaatggatt gtctatttcg agacgtttgg
    48301 aacatacctg tgatggaaaa aatgattaaa gagcgcttta atggcagata tcctgctcga
    48361 aaatcgattc aaacggaatt tgcacatcac ggtggaccac aaggactact ctttcaagtg
    48421 gatggtgtgg cttattcaaa acatatttcg atgacctaat caaggttact ttaagatcat
    48481 agtggtataa taacgttatg agatttctag aacttttaca aaagaaattt tttcctaaag
    48541 catatcagga aaaacaattc ttaatgcatc aaaaaacgcg tttaacgcca caacacaatc
    48601 aaaagcagta ttcgccaaat gccaatcatt tggactcatc agctaccaaa aactcagaac
    48661 aagaccctgc aatagctctg caacgcagta gagcctatga aggaagccct aaaagtcggc
    48721 ccgcttggtt gcaaaagttg gaagctgttt tgccgtctcc tcaacatcca attcggcgtt
    48781 tttggcgccg ctatcatatc ggaaaactgc taatgattct gattggaact cttgtcttac
    48841 tcttaggatc atacttgttt tacttatcaa aaacagctaa agtatctgat ttacaagatg
    48901 ccttgaaggc tacaactgtt atttatgatc acaaaggaga gtatgcaggc agtttatctg
    48961 gtcaaaaagg gagttatgtc gagctcaacg ctatttcaga tgaacttgag aatgctgtta
    49021 ttgccactga ggataggact ttttacagta atagcggtat taatcttaaa cgcttcttat
    49081 tggcggtagt tacggcgggc cgctttggag gtggctcaac gattacacag caactggcta
    49141 aaaatgctta tctctcacaa gatcagacaa ttaaacgaaa ggccagagag ttttttttgg
    49201 cgttagagtt gaccaaaaaa tacagtaaaa aagatattct tactatgtac cttaacaact
    49261 cctattttgg aaatggagtt tggggagttg aagatgccag tcaaaaatat tttggaacca
    49321 cagctgctaa cttaacattg gatgaagctg ccacattagc aggtatgctc aaaggacctg
    49381 aaatatataa cccttaccat tctctaaaaa atgctactca ccgtagagat actgttttag
    49441 gagcgatggt tgatgccaaa aagattaccc aaacaaaagc tcaacaagct agagcagtag
    49501 ggctaaaaaa tcgcttagct gatacttatg ttggtaagac agatgactac aaatacccat
    49561 cctactttga tgctgttatt agtgaagcaa tagcaactta tggcctttca gaaaaagaca
    49621 ttgttaataa tggatacaaa gtttacaccg agctagatca aaattaccaa actggcatgc
    49681 agacgacttt taacaacgat gaactatttc ctgtttcagc ttatgacggt agctctgctc
    49741 aagcagctag tgttgcttta gatcctaaaa caggaggtgt tagaggtctg attggtcgtg
    49801 tgaatagtag tgaaaatccg actttcagaa gctttaacta tgcgactcaa gcaaaacgta
    49861 gtcccgcatc aacaatcaaa ccactcgtgg tttacgcgcc agccgttgct tcaggatggt
    49921 caattgaaaa agaactacca aataccgttc aagattttga tggctatcag ccacataatt
    49981 atggaaatta tgaatcagaa gatgttccta tgtatcaagc attagcaaac tcttataata
    50041 ttccagcagt ttctacattg aacgatatcg gaatcgataa agcctttacc tatggtaaaa
    50101 catttgggtt agatatgagc tctgccaaaa aagagttggg ggtagcttta ggtggcagcg
    50161 tgacaactaa tccattggag atggctcagg catatgctgc ctttgccaat aatggagtaa
    50221 tccatcctgc gcacttgatt aaccggattg aaaatgccag gggtgaagtg cttaaaacct
    50281 ttactgataa ggctaaacgt gttgtcagcc agtctgttgc agataagatg acagccatga
    50341 tgctaggtac cttttcaaat ggaacagcag tcaatgctaa cgtatatggc tatacactag
    50401 ctggtaaaac agggacgaca gaaaccaact tcaatcccga cttagcaggc gatcagtggg
    50461 ttattggtta tacgccagat gttgttatta gtcaatgggt aggatttaat cagaccgatg
    50521 aaaatcatta tctaacggat tcaagtgcag gcacggcttc agctattttt agcactcagg
    50581 catcttacat tttgccttat accaagggca gccaatttca tgtagataat gcctacgctc
    50641 aaaatggtat ttcagctgtt tatggagtca atgaaacagg taatcaatca ggagttgaca
    50701 ctcaatctat tattgatggt ttaagaaaat cagcacaaga agcttcgcaa tcactatcaa
    50761 aagcagtcga tcagtcaggg ttacgtgata aagcccaatc tatttggaaa gagattgttg
    50821 actattttag atagcttgca gtattttaga gatcgtgtta aaataatagt tacggaggcg
    50881 ttatggcaca gaaaaaagcg agtctagcgt gtgtcgaatg tggcagtcgt aactactcta
    50941 tcggagtgag tagcacgcct aaaccaacac gtctagaagt aaataaattt tgcaaatact
    51001 gcaaaacata taccttacac aaagaaacac gttaaaaagg agagcctgat gggattcatt
    51061 agcgggactt ttaaagtctt aaaagacaca acatggccaa atcgtaaaca acgttggaaa
    51121 gattttatct cagttcttga gtacacagct ttctttacgg tgattatcta catctttgac
    51181 cagctcttag caaagagtgt attagcactg attaatttat tctaggtcaa gattggtaga
    51241 aatgataagc ttgcttggaa aagcctaggc tgggagtatt cccagccttt ttgtagtatc
    51301 aataatctaa ttagtaagct tttttaaagc ccatactggt ttgagcttta aaaaagcata
    51361 aaggtaaagg caatgtagca acgatctcca aaccaagttc actaaattag cttgtaacag
    51421 agtcaacgca taaacagcct ggcctcactt gcttagcaca ttaaaaatag caatgaatat
    51481 tatggttgag gaaaacagcc tgatagtctg ctaaatcttc gggatgataa gccttgacct
    51541 cagccatctc atactcccta cctagaagtt tgtacttgtt ttctccaaat tgatggaaag
    51601 gtaacagttg cacttggtca atctcaagct gattaaagag ctctgagaag gctttagcat
    51661 cgtctagtga atcattaaat tggggaataa cagggatgcg caagacgatt tcttttccag
    51721 cttgaaaggc ataatgaata tttttgataa tcaagtcatt acgaacccca gtcacttttt
    51781 ggtgtctgag ctgattataa tgtttcaaat cggtatagat aaagtccacg tagtcaataa
    51841 gggtgacaaa ttgctcgtgt ttggcaaagg cggtggtttc aattgcggtg tgaagacctg
    51901 ctgctttggc tgcttttaac agggctaagg caaagtcaaa ttgggcaaag atttcccccc
    51961 ctgacagggt catgccccca cctgactctt cgtagaaatc aaggtcttta aggacttctt
    52021 cgatcacctc gtccacggtt ttttcctctc caactatttt agtattaagc ccatcacttg
    52081 ttaacatctg ctcaggcgct ttttgttggg attcgggatt ggcacaccaa ggacatctca
    52141 aggggcaacc ttttaaaaaa acggttgtcc gaataccagg gccgtcatga atactaaaat
    52201 gttggatgtt gaaaacaata ccgcgatcag tcataagtgt gaattccttt cgttgtaaaa
    52261 ccatcatacc agataaacgt aaataaatca attacgaatg aaagtaaata tcccttttct
    52321 tttaagaaaa taactggtac aatgaaaggg aggtgaatga tgaatcgatt agaacgtatt
    52381 attcaactgg tttcccagaa gaaaaaaata gatgttaaca gtttatcaga gcaattagaa
    52441 gtttcgaaag taaccattcg aaaagacctt gataagcttg aaagtaaggg cttgttgcga
    52501 cgggaacatg gctatgcggt gctaaacagt ggcgatgacc tcaatgtacg cttgtcctac
    52561 aattacaaca ttaagcgacg gattgcagaa aaagcagctg aattggtgca agacaacgat
    52621 accattatga ttgaatctgg ctcaacctgt gcccttttgg cagaagtgct ttgccagacc
    52681 aaacgaaata ttaaaatcat taccaattcg tgcttcattg ccaactacat tcgtcaatat
    52741 agtagctgtc aaatcatttt actgggtggt tattaccagc ccaattcaga ggtgactgtt
    52801 ggtcctttat tgaaagaaat gatatccctt tttcatgtca atcgtgtctt tgttggaaca
    52861 gacggtttca acaaagatct tggctttatg ggcaaggaca tgatgcgctc agaaggggtg
    52921 cgttacatgg cagatgctgc tgaggaagtg gtgattttga ccgattccag caagttttca
    52981 aaaaccagtc tggtacacca gttgtcatta gctgatgtca atcgcgtcat tacagaccaa
    53041 gcactagaca agcaaacaca agagttatta agttctggtg gtcttgttct tgattttgtt
    53101 tcttagaaaa taggtggcta gatgaaagaa gaacgcagac ggctccttgc caaggtggct
    53161 tacttgcatt atgttcaagg caagagccaa accttgattt caaaggaaat gaatatctac
    53221 cgaacaacgg tttgtcggat gttagcaaaa gccaaggaag aaggcattgt tcggattgaa
    53281 attgccgact atgatgctga tttatttgct ttagaagaat acgtgcgaaa gcagtacggc
    53341 ttggaaaaac tagaccttgt gcccaaccag gttgaagata ccccaatgga taccttgaca
    53401 aatgttgcta aaacagcagc tgaggttttt agacatgttg ttaaagatgg cgataagatc
    53461 ggtctgtcct ggggagcaac tctttcttgc ttgatggatg agttaaatcc aaaagcgatg
    53521 aaagatgtgt ttatttatcc tttggcagga ggacctagcc atattaatgc caaataccat
    53581 gtcaataccc tggtttaccg cttggctcgc atctttcatg gtaatagcgc ttttatgaac
    53641 gctatggtca ttcaagaaga caaacacttg gctaagggaa tcttacaatc taaatacttt
    53701 aacgacattt taacaagctg ggaccagcta gatcttgcct tagtaggaat tggtggggag
    53761 cctaatagcc ttgagcagag ccaatggcgt gatttattaa ccagctcaga tcatgaccaa
    53821 ctcaaatatg aaaaagccgt tggtgaagtt tgttgtcgtt tctttgatca ggcaggtcag
    53881 ccagtttaca ctggcctaca ggatcgaact attggtattt cgctagaaca gttgaggcgt
    53941 gtccccaaaa caatggctgt tgcaacaggt aaacacaagg ctaaggcaat attggcagcc
    54001 ttaaaagcag gttttatcaa ttatctagtg acggataaag agaccatgct agctgtttta
    54061 gcgttagatg aagatattga tcttaataac gttcttcttt aatagaaatt caaagatact
    54121 atgatattta tagaggccca agaccaaacg gtcagggctt ttttgtttga tgtgttgatg
    54181 aaacagagat tgctcaaatg tgcagttaat gtattggcac aaaagtgcat taaccaaaat
    54241 atagcacaaa atatattgac cctaaaaaca aaaatgatac aataaactta ccaacgaaat
    54301 gtaaacgatt acaaaaacaa taacatcacc ttcgaaaaaa agactcattg ccgttacatc
    54361 acatgaaaaa gaaaaaaagg agacaccaat gcaagttatt gtaccagacc aaatcattat
    54421 gggcttaatt ttaaatgcag gcgatgccaa acaacatatc taccaagctc tgaaatgtgc
    54481 taaagaggac gattatgcca ctagtgaaaa agaaatggca ttagcagatg atgccttgtt
    54541 ggaagctcac aatttacaga cccagtttct tgcccaagaa gctagtggta ataagtcaga
    54601 gattacagct ctttttattc actcacagga tcacttgatg acgaccatta cagaaattaa
    54661 tctcatcaaa gagattattg accttcgtaa agaattggca accaaataat atttcattca
    54721 taaaaaggag attgatatga ttaagattgg attgttttgc gcagcagggt tctcaacagg
    54781 catgttggtg aacaacatga aagtagctgc tgaaaagaaa gacattgact gccagattga
    54841 tgcttattcc caaggaaagt tggctgagta tgctccattg attgatgtgg cacttttagg
    54901 cccacaggtt gcctatactc tggataaatc agaagctatt tgtaaagaga atggcatccc
    54961 gattgcagtt atcccaatgg ctgattatgg aatgttagac ggcaacaagg tgcttgattt
    55021 agcccttagt cttgttaaag aataggagtc aatcatggca aaaatgaata tgcaaaacat
    55081 catcatgcca atcatgaaat ttgtgaatat gcgcggcatc atcgccttaa aagacgggat
    55141 gttagctatt ttacctttga ccgttgtggg aagtcttttc ctgattgctg gtcagattcc
    55201 ttttcaaggg attaatgatg ccattgccgg tgtgtttggt gccgactgga cagaaccctt
    55261 tatgcaggtt taccatggaa cgtttgctat tatgggcttg atttcctgct ttgcgattgg
    55321 ttattcttat gctaaaaatt caggtgttga acctctccct tcaggggttt tatccttatc
    55381 agctttcttt attctattga gatcatctta tgttccagca gaaggcgaac ctatcggtga
    55441 tgctattagc aaggcttggt ttggtgggca agggattatt ggtgctattg tgattggttt
    55501 aacggtaggt gctatttata cagcatttat ccgtcgccac attgtcatca aaatgccaga
    55561 gcaagtgcca caagccattg ccaaacagtt tgaagctatg attccagcct ttgtgatttt
    55621 taccttgtca atgcttgtgt acattattgc caagtcagtg acaggtggtg gcacctttat
    55681 tgaaatgatt tatgatgtca ttcaggtacc gctgcaaggg ttaacgggtt ctctttatgg
    55741 cgcactaggt attgccttct ttatttcctt tctttggtgg tttggcgtgc atgggcaatc
    55801 tgtggtcaat ggaattgtca ctgctcttct cttatcaaat ctagatgcca ataaggcctt
    55861 gatggcagca ggtgagttat ccctagacaa gggtgcccat attgtaaccc aacaattttt
    55921 agactctttc ttgattctat caggttctgg tattaccttt ggtttagtgg tagctatgat
    55981 ctttgcggct aaatccaaac aatacaaggc tttaggtaag gttgcagcct tcccagccct
    56041 ctttaatgtt aatgaacctg tcgtctttgg ttttccaatt gtgatgaatc cagtcatgtt
    56101 cttgccattt atcttggttc ctgtcttggc agctctcaca gtttatggcg ccattgctat
    56161 tggtttcatg cagccctttg caggagtgac ccttccgtgg tcaacaccag ccattatctc
    56221 agggttcatg gttggtggct ggcaaggagc tattgtgcaa attcttatac tcatcatgtc
    56281 aacgttggtg tacttcccat tctttaaaat tcaagataat atggcttatc aaaatgaaca
    56341 agctagtgaa gagtcatgat ttagcgtcca cacaaattct tgagaccatc tccagttaga
    56401 ggtggttttt tagaaaaaga agagcgactt atcaggttca tattgcacaa tagtgcaaaa
    56461 taaagtgact atctcttctt atggttaagg atacgcaaaa gtcgcaatat atgataaaat
    56521 agttacgaaa gaaacattta taatttcgta agaaagaagg agatcccgca tgactgaaac
    56581 aaaaagccct tattttggac atttaacaga cagaatgact cactatcgtg aagctgtgtt
    56641 agacaagaaa ccttatattg atgctgagcg tgctatttta gccactgaag cctatcaaaa
    56701 acaccaaaat aagccagcaa acctcaaacg cgcttacatg cttcaaacta ttttggaaaa
    56761 catgaccatc tatattgagg acgaaagcct cattgctggt aaccaagcct cttcgaacaa
    56821 ggatgcgccg attttccctg aatatactct ggaatttgtc ctcaacgaac tcgatctttt
    56881 tgaaaaacga gatggggatg tgttctacat taccgaagaa accaagcaac agctgcgaga
    56941 tattgcccca ttctgggaaa acaataactt acgtgctcgc tgcggggtct tgctaccaga
    57001 agaagtgcaa gtgtacatgg aaacaggttt ctttggcatg gaaggcaaga tgaattcggg
    57061 agatgcccat ttagcggtca attaccaaaa actcttggaa cacggcttga agggatttga
    57121 agagcgggca cgagctgcca aagctgcgct tgatttgact attcctgaaa atattgacaa
    57181 ataccatttt tacgattcgg tttttattgt cattgatgcg gtcaaaactt atgctaaacg
    57241 ctatgccaag ttggctagag aactagcaga aaccgctagt ccagaacgtc aagcagaatt
    57301 gttagaaatc gcacgcattt gtgacaaagt accttatgaa ccagcagcaa cgtttgcaga
    57361 agctgtgcaa tccgtctggt tcattcagtg tatcttgcaa attgaatcaa acgggcattc
    57421 cctatcttat ggccgctttg accagtacat gtatccttat gtcaaggctg atttggaggc
    57481 tggccgtgaa acagaagcct caatcgttga acgtttgacc aacctctgga ttaagaccct
    57541 gaccattaac aaagtgcgga gccaagccca caccttctca tcagcaggta gtccacttta
    57601 ccaaaacgtg actattggtg gtcaaacacg agataaaaaa gacgcggtca acccactgtc
    57661 ttaccttgtc ctaaggagtg tggctcaaac caaattgcca caacctaact tgactgttcg
    57721 ttaccacaaa ggtctagaca atacctttat gaacgagtgt atcgaggtca tgaaacttgg
    57781 ttttggtatg ccagccatga acaacgatga aatcatcatt ccatctttca tcaaaaaagg
    57841 tgtctcagaa gaagacgcct atgactactc agccattggc tgtgtggaaa cagcagttcc
    57901 aggaaaatgg ggctaccgtt gcacggggat gagttacatc aacttcccta aaatcttgct
    57961 gattaccatg aatgacggga ttgacccagc atcaggcaag cgctttgcaa aaggacacgg
    58021 tcatttcaaa gacatgacct cttatgaaga attaaaagca gcatgggatg ccaccctgcg
    58081 cgaaattacc cgcatgagcg tcattgttga aaatgccatt gacctaggtc ttgaacgtga
    58141 agtaccagat attctttgct cagccttgac agatgattgt atcggtcgtg gcaagacctt
    58201 aaaagaaggc ggagctgttt acgactatat ctcaggcctt caagtcggta ttgccaacct
    58261 atcagactcc ctagcagcgc tgaaaaaatt agtatttgaa gaaggtcgat taactccaga
    58321 agaactctgg cacgcccttg aaagtgactt tgctggagag cgcggagaag agatccgaca
    58381 aatgctcatc aatgacgcac caaaatatgg taatgatgat gactacgcag atagtttagt
    58441 tgtcgaagct tacgacacct acattgatga aattgccaaa tacccaaata cccggtatgg
    58501 tcgtggccca atcggaggta tccgctattc tgggacatca tcaatctcag ccaatgtcgg
    58561 acaaggaaaa ggaaccttgg cgacaccaga cggtcgccat gcaggcacac cactagcaga
    58621 aggctgttca ccagaacaca gcatggacaa aaaaggcccg acttcagtat tgaaatctgt
    58681 tgctaaatta ccaacagatg agattgtcgg aggagtgcta ctcaaccaaa aagttaaccc
    58741 acaaaccctg gccaaagaag aagacaaact gaaattaatg gccttacttc gtaccttctt
    58801 taatcgccta cacggttatc atatccagta caatgtcgtg tcacgtgaaa ccttgattga
    58861 tgcccaaaac catcctgaaa agcaccgcga cctcattgtc cgtgttgctg gctactcagc
    58921 tttcttcaat gtgctctcaa aagcaaccca agatgacatt attgaacgta cagaacacac
    58981 actttaggag aaaataagta tggaatacat gttagacact ttagatttag aagcgattaa
    59041 aaaatggcat cacattttgc ctctcgcagg tgtgacctca aacccttcta ttgccaaaaa
    59101 agaaggtgac attgatttct ttgaacggat tcgagaagtc cgtgctatta ttggtgacaa
    59161 ggcttctatt catgttcaag tgatcgccca agattacgaa ggcatcttaa aagatgctgc
    59221 tgaaatccgc aggcaatgtg gagatagtgt gtatgtcaaa gtacctgtaa ccacagaggg
    59281 ccttgcagcc attaaaacct tgaaagccga aggctatcat atcacagcaa ccgctattta
    59341 tacgaccttc caaggactat tagccattga agctggtgct gattatttgg ctccttacta
    59401 taaccgtatg gaaaatctca atattgatcc agaagctgtc ataggacaat tagccgaagc
    59461 tattaaccgc gagaatgctg atagtaagat tttggcagca agctttaaaa atgtggctca
    59521 ggtcaataaa tcctttgctc taggagcaca agccatcact gctggcccag atgtgtttga
    59581 agcaggattt gccatgccat ctattcaaaa agcggttgac gattttggca aggattggga
    59641 agccattcat caccgcaaga gcatttaaga aatagcatca gtagtaatca catcattagg
    59701 aatcacagat aaaggagttc aacgatgaaa gtatttgcaa gtccatctcg ttacattcaa
    59761 ggtaaaaatg ccttgtttac caatgctaaa accctaaaac aactagggga tagtcccatt
    59821 ttactgtgtg atgacgtggt gtatggcatc gtcggagaaa gatttgaaag ctatttgata
    59881 gataatggca tgactcctgt tcacgtagcc tttaatggcg aagcctcaga taatgaaatc
    59941 agtcgcgtgg ttgccattgc caaggaaaat ggcaatgatg ttattatcgg tcttggtggt
    60001 ggaaaaacca ttgacagtgc taaggctatc gctgacttac ttgctgttcc ggtgattatt
    60061 gccccaacca ttgcttcaac agatgcccca acctcagcct tatcggttat ttataccgat
    60121 gaaggagcct ttgaaaaata cattttctat tcaaaaaatc cagatcttgt tttggttgac
    60181 acacaagtaa tctgtcaggc accaaaacga ttactggcgt cagggattgc agatgggtta
    60241 gcaacatggg tagaggcgcg tgctgttatg caaaaaaatg gagacaccat ggcaggtggc
    60301 aatcaaacct tggcaggagt tgccattgcc aaagcctgtg agcagacctt gtttgcagat
    60361 ggcctaaaag cgatggctag ctgtgacaga caagtcgtga ccccggcctt ggaaaatgtc
    60421 attgaagcca atacacttct tagtgggctt ggttttgaaa gtgcgggtct ggctgctgca
    60481 catgccattc acaatggctt tacagcgctg acaggtgcta ttcaccacct tacccatggt
    60541 gaaaaagtcg cctatggtac gttgacccaa ctcttcttgg aaaatcgttc gcgtgaagaa
    60601 attgaccgtt acatcgactt ttaccaagcc attggcatgc caacaaccct caaagaaatg
    60661 catttagaca cggctactca agaggatttc ttaaaaattg gccgtcaagc aaccatggca
    60721 ggcgaaacca tccatcaaat gccatttgtt atcagtccag aagatgtagc agcggctttg
    60781 gttgctgttg atgcctatgt tacgagtcga taggttaacc aaaaagattt cttgataatc
    60841 taaaaaaccg gtctagggat atattcctag actggttttg cttattgttg gttggtaata
    60901 gcacttttag cggggtcatt gtgggcaata cggctggcag ctgcagcagc aatggcgcta
    60961 acaatatcat ctaaaaaggt atggcaggag tagccatctt tgtggttgag tttgtcaaca
    61021 atccccggtt ttgtcttgtc cagataccca taattggtaa aaccgataga cccatagagg
    61081 ttaacaatgg ataaggccag gatttcatca atcccataca gcccttggtc ggttttcaag
    61141 atactaagga gtggctcaga cagctggttg gcttcagcca atttatccaa ttctacccca
    61201 gtgataatag cattttgcac ttctcgtttt gcaagcaccg cttcaacgct ctctaaacat
    61261 tctgccatgg tcaaattggg aatataatca ttctgcaaaa aaagcaccag ctctgcaata
    61321 gcttctaaag aaacccctcg ctcagccagt aattgataag acacttctcg taggtgatgg
    61381 tcagttgaca tgtgagacct cctttttttt ctttattgta acataaaaga tttcgagaaa
    61441 cctctacaac agctaaagag gggatagttc ttttttaaga gatgttgact actgagatcc
    61501 cctacttggt aaaagtcaaa gcaacgatag taaagtaacc atcttaccta ggcctaaata
    61561 caatcaccac ccctaggtga cacacagcac ctatttcaaa aatgatatta gtatggcaaa
    61621 acaaaaagac aacgccttct tttttctcct tactatctcc tttaattttc atatttttta
    61681 aaaaaactat tgataaacta gttaagtaag cgtatactat ggttagtgag cgaaattaga
    61741 aaagaggaca agcatatgaa tctacttgga tcaagacggg ttttttctaa aaaatgtcgg
    61801 ctagtaaaat tttcaatggt agctcttgta tcagccacaa tggctgtaac aacagtcaca
    61861 cttgaaaata ctgcactggc acgacaaaca caggtctcaa atgatgttgt tctaaatgat
    61921 ggcgcaagca agtacctaaa cgaagcatta gcttggacat tcaatgacag tcccaactat
    61981 tacaaaacct taggcactag tcagatcact ccagcactct ttcctaaagc aggagatatt
    62041 ctctatagca aattagatga gttaggaagg acgcgtactg ctagaggtac attgacttat
    62101 gccaatgttg aaggtagcta cggtgttaga caatctttcg gtaaaaatca aaaccccgca
    62161 ggctggactg gaaaccctaa tcatgtcaaa tataaaattg aatggttaaa tggtctatct
    62221 tatgtcggag atttctggaa tagaagtcat ctcattgcag atagtctcgg tggagatgca
    62281 ctcagagtca atgccgttac aggaacacgt acccaaaatg taggaggtcg tgaccaaaaa
    62341 ggcggcatgc gctataccga acaaagagct caagaatggt tagaagcaaa tcgtgatggc
    62401 tatctttatt atgaagccgc tccaatctac aacgcagacg agttgattcc aagagctgtc
    62461 gtggtatcaa tgcaatcttc tgataatacc atcaacgaga aagtattagt ttacaacaca
    62521 gctaatggct acaccattaa ctaccataac ggtacaccta ctcagaaata ataccaaaag
    62581 gctagacctc tgctcactag gcctagcttt ttacatcaaa aaaagcaatg actatagaaa
    62641 gtaaaaatac tagaaaaagc aatgattgcc gtcattgctt tttatgattt gtcaaaaagt
    62701 aaaaagcaaa ttgaaaaaat cgccctggag ctgttgagat aaactacacc atttattaag
    62761 ataccaaatc aaaaagctaa caccataaga gcgttagctt tttaaagagc ctcaggacag
    62821 tttatgttta atggcttcta ggtaggtttg aaacatatga tggatcgttt tgcaattaag
    62881 taattggaag atctccaaga tctgcacaca cttttgctca gccccctctt taccatttat
    62941 gaggccaata atgccatcaa aaaaagacac acaacaccgt tcatataagc aatcatcatt
    63001 tagctgataa tcttcaattt ttgccaaaat ctcagaagct ttatcatact cttgtcgctg
    63061 aataaacaaa atcaacatat tgacaaacat ccgaatcgat tcattcccat aataccttag
    63121 ggtattgtat ttatcgaggt tcaaaataac ttttgaaaac accatctcaa taaagcaaga
    63181 ctcaaaaata aacatacaat tattaaaaag cacagtctca tagtgactcc aagtttcaat
    63241 attaataaga tagtttgaca aataagtccg ctctgtcaga cagtcttcct cagtaagagt
    63301 tgctaataac accttgacca aggcaaaaag gttcttttcc tttgttgact tactatcttt
    63361 ataagaatca aggatatgat ttaaaccttc tatgtttcgg cactcaaaat aatgttttgc
    63421 cgtatccata tcaataaatt ctttatattg tttaaagtta ttactaataa agagaaactc
    63481 atcaacattg acattcaagt tgtctaagat ataaagtaac tttttcgaag aaatgtcaag
    63541 attattttta ataaaacgat aataggtttg cctagtgaga taatcaccac aaacttgttt
    63601 aatcgaaatg ttttttgaat gcctaatgaa ttcaacggtt tcaccaattt ccatatgtca
    63661 agccttccta gttgatgtca aaaatacgtt acgcatgtac ctaatacgta acaagttgaa
    63721 tgtttcggat gatagtcgct tatgataggt gcataaggtc aatagccaga tgcgatagtt
    63781 ttatcaactg tcatatgtta aacctttcta atctaataga tgttaaaaat acgttacgtg
    63841 tgtacctaat acgtaacaaa ataatgggtt agcaaaataa gcagctatga tatagccata
    63901 aggttaaaag gaggcgccta ctatgtggtt attgttacta tttttgtagt tccttttgca
    63961 aaatggtagt agataaaaat gagaagtcaa taaaagcatt gacaaacaaa agaatcattt
    64021 tgtttatatt atcagtattt ttaagtttct tgtcaactga aatgagcatc tactagccac
    64081 aatagtaact aaaaggctaa ttgtcagtaa aaatgagata aatcagccag gaaaaagcct
    64141 acgagtcaac taatggacaa cccaaaaaaa gacaaaggac tttcacttgg tgttgtggac
    64201 cctatcacga tccttatcac agaatcagtt attaacaaaa tgagaacggt cccatatcat
    64261 ctaaaaaaac tgtcaagcac aacctattgt ttgctagctg atcttgccta tcagtctgcc
    64321 tagcagatac ggcagaagat aagagatcaa ccaaaagatg ataagtgcaa cgactcatag
    64381 cgtcttttga ccaaaaccaa ttaggctcac atgagatgag aataattggg ttgggttgtc
    64441 agtgttaact aaccgtgtta ttgtctatta ccattcatgg tatcagcgac atcgtatgat
    64501 aaccatacga ttcagctaag taaggaggtg tgtccaatgt accgttaaaa gcaaatgcag
    64561 tagattaact tattttgaaa gaggtataaa aaaaatgaat aaaaagaaat taggtatcag
    64621 attattaagt cttttagcat taggtggatt tgttcttgct aacccagtat ttgccgatca
    64681 aaactttgct cgtaacgaaa aagaagcaaa agatagcgct atcacattta tccaaaaatc
    64741 agcagctatc aaagcaggtg cacgaagcgc agaagatatt aagcttgaca aagttaactt
    64801 aggtggagaa ctttctggct ctaatatgta tgtttacaat atttctactg gaggatttgt
    64861 tatcgtttca ggagataaac gttctccaga aattctagga tactctacca gcggatcatt
    64921 tgacgttaac ggtaaagaaa acattgcttc cttcatggaa agttatgtcg aacaaatcaa
    64981 agaaaacaaa aaattagaca ctacttatgc tggtaccgct gagattaaac aaccagttgt
    65041 taaatctctc cttgattcaa aaggcattca ttacaatcaa ggtaaccctt acaacctatt
    65101 gacacctgtt attgaaaaag taaaaccagg tgaacaatct tttgtaggtc aacatgcagc
    65161 tacaggatgt gttgctactg caactgctca aattatgaaa tatcataatt accctaacaa
    65221 agggttgaaa gactacactt acacactaag ctcaaataac ccatatttca accatcctaa
    65281 gaacttgttt gcagctatct ctactagaca atacaactgg aacaacatcc tacctactta
    65341 tagcggaaga gaatctaacg ttcaaaaaat ggcgatttca gaattgatgg ctgatgttgg
    65401 tatttcagta gacatggatt atggtccatc tagtggttct gcaggtagct ctcgtgttca
    65461 aagagccttg aaagaaaact ttggctacaa ccaatctgtt caccaaatca accgtagtga
    65521 ctttagcaaa caagattggg aatcacaaat tgacaaagaa ttatctcaaa accaaccagt
    65581 atactaccaa ggtgtcggta aagtaggcgg acatgccttt gttatcgatg gtgctgacgg
    65641 acgtaacttc taccatgtta actggggttg gggtggagtc tctgacggct tcttccgtct
    65701 tgacgcacta aacccttcag ctcttggtac tggtggcggc gcaggcggct tcaacggtta
    65761 ccaaagtgct gttgtaggca tcaaacctta gtatggaaat gcatttcgtt agaacagaac
    65821 ctgaggcacg ccgcatagct gaaacctttt gtgccgaaaa cacacaaaca aaacccccta
    65881 tgcgcgtgca gcagttaagc tatccatcag acacagatca ctcaagtggt gagctataca
    65941 tctatgcttt gtctcctgct ggatttatca tcgtatcagg agacaccaga gcgcacacca
    66001 ttttaggcta ttcttttgat aataacctag acctcaacca tgataatgtc aggagtatga
    66061 tagaagctta ccaaaaacaa atcaactctt tggattgatc ggtcaaagta gcttttgccc
    66121 ccctcaccac tcgtttaaga cgaccgtgtt tctaaaatac cactaccttt taagtttcac
    66181 gccggcctaa gcgagtgttt gtctcatgga gcagactgtt tccatcgaaa agtcacccat
    66241 tgataaagga ggtcatcaac gcctactaat gatgacttcc ctaagatgcc aaggtaaagg
    66301 actgagttct gtagagatgg gactcagtcc ttttacgatt tttgggagtt attctagcca
    66361 taccgtggca agaaaacaac actcaaaaat agccaacgtc agtttctgtt catacatgac
    66421 tacagccaaa caccacaacc taacctatcc taaacacaat ggctttctaa cgaacagtca
    66481 caacgagcag caacaccaaa aagcaagatt aagctacgtt taagactaat gatataagat
    66541 aacagtaatt attaatgaga aaagaggctc aggacatgaa acaaatgaat aaactcatta
    66601 caggagtggt aacgctggcg acagtcgtga ccttgtcagc ttgtcaatca tcacacaaca
    66661 acaccaaact cgtctcgatg aaaggagaca ccatcactgt cagtgacttc tacaatgaga
    66721 ccaaaaacac agaactcgca caaaaagcca tgttaagctt ggtgattagc cgcgtttttg
    66781 agacacaata tgccaacaaa gtctctgaca aagaggttga aaaagcctat aaacaaaccg
    66841 cagaccaata cggtacatcc tttaagacag tcctagcaca atcaggctta acgccagaaa
    66901 cctataaaaa acaaattcgc ctcacaaaat tagtcgaata tgccgtcaaa gaacaagcca
    66961 aaaacgaaac catctcaaaa aaagactacc gtcaggccta tgacgcttat accccaacca
    67021 tgaccgcaga aatcatgcag tttgaaaaag aagaggatgc caaagcagcc cttgaagccg
    67081 tcaaagctga aggggcagac tttgcagcta ttgccaaaga aaaaaccatt gcagccgata
    67141 aaaaaacaac ctacacgttt gactcaggtg aaacaaccct accagcagaa gtagttagag
    67201 ctgcatcagg cctcaaagaa gggaacagat cagaaatcat cacagcgctt gatccagcca
    67261 cctcaaaacg aacctaccat atcatcaaag tcaccaaaaa agcaactaaa aaagcagact
    67321 ggaaagcgta ccaaaaacgc ttgaaagaca tcatcgtgac tggcaaatta aaagaccctg
    67381 acttccaaaa caaagtcatc gctaaagctc ttgataaagc aaatgtcaaa atcaaagaca
    67441 aagcatttgc caatatctta gcccagtttg caaaacctaa ccaaaaacaa cctgcccaaa
    67501 aatagagggc tgccagttta tttccctaag gttgcttaaa aagacagccc tagccatcac
    67561 tccccttttc aaaacaccga taatggaaac gtgtcctata ctgatggtct agggcaatgt
    67621 cataaagcta aagactctat ccaaataagg atagagtctt taatatttaa aaaccagtca
    67681 gcaaaaaaat tcacgctaag cctagaatga ggcttagcgt gaatggtatc agtgatagtc
    67741 cgttaacata gctgattggg agtcagaaac tctaactacc caatctgact atacccccag
    67801 taccagaggt gtctcatcgc agaagtagca atcagataat cgtctgataa gctcttgtcc
    67861 tcaagcaact gatgagtatc gtcgcacggg ccatgagctg ccggtggctg atagctagta
    67921 ggctcatcag ccaaaacttt tttggagtaa cgctttggtc tcagacggcg ccagagggtt
    67981 gagagagggg tgagaaaaaa acgatgggtc atcttggcct ccttgtctaa tgatagtcac
    68041 gttaacagac aaaagtgtta ataatgtcat tttaaggaga aaaagattaa aaatcaaggt
    68101 cacaaacttt tctttgttaa aaaaacgcga ccctaataaa gaacctaaat ctccctcgca
    68161 cttgagcttc tccttgcgca gctatcttgc gcacacagtt gcctccaaac taatgatagc
    68221 gataccatta ttgtcctata ggctatcgcg acaacccctt ttttcgcctc aatgaggctg
    68281 atacatctgt catgacagaa aaaagaccct tgtctatcta agggaccatt aatttttctc
    68341 tcaccaaaaa actgatttta gaaacgaaga agcatagtgt ataataaagt tcggaacaat
    68401 tatgacataa taatgaaagt aaggttaacg aaacattgac aaattgtaag tataaactta
    68461 gaaagttatc tgtagggctc gtctccgtcg gaacgatgct gatagccccg acagttttag
    68521 gacaggaggt tagtactaat actgagacga gtactactac agccaccact actcctagtg
    68581 ctggtaccgg taaggcaaat ggaacagctg ccactactcc tagcgctggt acaagtactg
    68641 gtgaagcaac cgtagctact gccactacta ccaatggagg aagtcagtct actccagcag
    68701 tagctgaagc gactccacaa ccccaagcac agacagttac agcaactaca tctacatcat
    68761 cgacttcttc tagtgatgag aaaagtaaca aggcagcaac tgcaactaca tctacatcac
    68821 cttcaactcc agtagtagcc agtaataata gcaatcaaga agctagtact gaagctgaaa
    68881 ctccaatgat ggacgtggaa cagtatacag ttgataataa agaaacagag cttaaggtta
    68941 aagacggtga taagtcaaaa aacgggaata gtattagtaa agatacaaaa cttattagaa
    69001 accgtgatgg cgagcagcgt gatattgttg atatcaagcg tgaagtaaaa gataatggcg
    69061 acggaacctt agatgtaacc ttaaaagtaa cgcctaaaga aattgacaaa ggtgccgatg
    69121 ttatggccct tttagatgtc tctaaaaaaa tgtcagaaga tgattttaac aacgctaagg
    69181 ataagattaa gaaattagtc aaaaccttaa cgagtaactc agataatgat gagcataaac
    69241 ataattctcg aaattcggtt cgtctgatga ctttttaccg tgagattagc aagccaattg
    69301 atatatcagg aaagacagat gatgagcttg atgagctatt agataagctt cgtcaaaagg
    69361 ctaaggatga gtatgattgg ggggttgact tacaaggagc tatccataag gctcgagagg
    69421 tttttaataa tgaaaataat gatggcaaaa agaaatctgg taaacgccag catatcgtcc
    69481 tattctctca aggcgagtca acctttagtt atgatattaa aaataaagat gataaaaaat
    69541 tacaaaaaac tcgtttaacc acagtgacga cctctaatcc attattttct tggtttccta
    69601 tctttgacca cacaaatcga aaagcggaca tgcttgacga ctttgataaa ttgctttcta
    69661 tagctcaaaa gtttggagta gaaataccta gtgggataaa aattggattg aagacggcaa
    69721 gtgcaggaaa ctttttatta ggcagtctta cagggagcga cagcttaaca gactatttaa
    69781 ctcttcgaga gtacgtggca gataaactgc aagaaacgga ctttgattac tccaatcgag
    69841 ttggagaggg ttatcattac cacagttttt ctgaacgcaa attaggcggt ctgccaatgg
    69901 aaagcacttt taaaacttta ttaaatacta atgtccctaa gttagacgat aagacttggt
    69961 tcggctggac tatgaataaa ttatcgttag cagataaata tcacagtttt caaaaagaaa
    70021 tactactaaa aattcttgaa tatctttttt acaagcgtga ataccactac tataatcaca
    70081 acctttcagc tattgctgaa gccaaaatgg cgcagaaaga gggtattacc ttctattccg
    70141 ttgatgttac tgtttcaaaa acaactccta aaagagtgaa gcgacaaaca gcagtacgtc
    70201 agggaaccgc gaaaaaagaa tccgaagaag agcgcaataa aaagtttgat gagtatctga
    70261 aaaagatgtc tgaaggtaat gatttcttaa gtaatgttga agcgagggat aagttcaaag
    70321 atactttaac agagcttaaa attaaagatg aattttcaga taaggttacg gttcagaata
    70381 attcagaagg taaaaaatac cagggaacta gcttaactaa cgatatacca aatgttgaac
    70441 ataagcaatt acaagaaaaa aaaggatggc tttcatcagg taataaagaa agcctcactt
    70501 ggaccatttc caaagagcag ttgaaacaag cctttgaaga tggaaaaccg ttaaccctca
    70561 cctataagct taaagtcgat aacgacaagt ttaaaacagc tctcgagaaa aagaagagaa
    70621 caaaacgttc tgcacctaca gaaaatgaaa actctgtcac agaaaatatc atttcaaata
    70681 ctactaccta caaaattaat gatcaagaag ttaagggtaa caaacttggt gatgttaatc
    70741 tgacatacag taaactcaag gttcctgtac cacagattga tggccatgtt attgagccac
    70801 aagcacctaa attacctgac ttacctcctg ttattgagcg tggacctgtt cttgattaca
    70861 cagaagaatc aatataccga ttaccacttg gacatggtag caatgcacca gacacacaag
    70921 tgacaattga agaagacaca gttcctcaac gcccagatat ccttataggc ggtcagagtg
    70981 gaccggttga catcaccgaa gatacccaac caggtatgtc aggctcaaat gacgcgacag
    71041 ttgtcgagga agacacagca cctaaacgtc cagatatcct tgttggcggt caaagtgatc
    71101 caatcgatat catcgaagac acccaaccaa gtgtgtcagg ctcaaatgac gcgacagttg
    71161 ttgaggaaga cacagtacct caacgtccag atatccttgt tggcggtcaa agtgatccaa
    71221 tcgacatcac cgaagatacc caaccaggca tgtcaggctc taatgacgct actgttatcg
    71281 aagaagatac gaaaccaaaa cgcttcttcc actttgataa cgagccacaa gcaccagaaa
    71341 aacctaaaga gcaaccatct ctcagcttac cacaagctcc agtctataag gcagctcatc
    71401 acttgcctgc atctggagac aaacgtgaag catcctttac aattgctgct ctaacaatta
    71461 ttggagctgc aggtttgctc agcaaaaaac gtcgcgatac cgaagaaaac taaccctcgt
    71521 tagtctagcg accctaagcc tttggcttta aaaatttctc attatccccc tcaaacaccg
    71581 gtacctcact gagatggcgc ttaaaaaagg cgctagtctc aaatcaggta tcccctacgg
    71641 ttgaggggga ttaatgggta tcacaacaag aaaaaaggta taatgatgaa atatgactaa
    71701 aaaatttatt aaatcagcag tgattctagg cttagcaagc ataaccatca gcatgacgca
    71761 acccgttgaa gccatttcaa atagcttaga atatcaacga caatataaac gtgtcaaaaa
    71821 agaactagac gcattaaaag aaaatagccc aaaattagga gaacgttccc tttattttag
    71881 attggtgaat aaatttctaa gttggtttgg ccaagtctgg gacccactcg caatcaaaga
    71941 aaccgatcac ctgttggacc tcatcggaca agtcaattac ttggtgagta acaccgagtt
    72001 tcaagcccct gagtaccaaa aggctaaaaa caaactagac ttagctgtag caggctatga
    72061 gctctaccta gctagagaaa aagaacgtgg tgatgctcct gattaccaag tgacccagct
    72121 aacgctagca cagctcaaaa ccatcaaaac gaagatacaa gaggccctga aaacatttgc
    72181 acaagaggtc aaaacaatcc aacaaacaca cccagaccta tttccccatg cttatgtttt
    72241 aaacgctaca accagtgcta tcgatggtaa agcgtacact tttttagtga atagctacta
    72301 cgatgtcttt tataagcagt ttttattcac taatacaaag gacgggtaca actataataa
    72361 agaagcagac aatctgacct cgtatcaaga tctgattaaa gagctattag acttaaaagc
    72421 tgagatcgat cagttaacaa aagacaagcc tacaaacgat cgtttagaga cgttaatgtg
    72481 ggaatcaaag ttcaccttat ctgattcacg gagaacttca cgccttagcg cctactatac
    72541 acaagaagat tatgtcaata aggtggtcct atctgaagaa gctcccaact tgagaacagc
    72601 aaaagaaaag gtcaagacct taaaagggat cttgtatgat tactatgttg atattaaaga
    72661 tccagaaaaa gctaaaaagt atcgtgtcga ggacgagacc ttgccgtctc aacctgaggc
    72721 ccctgctaaa cctgaagctc ctggtcaaaa accagcagaa gatgagggat cgtcacaagc
    72781 tacggagcca gctaacccgt caaaagagga ttcctcaacg gacgcatctc agggatctca
    72841 cgatagtgaa aacccagcga cagacagtcc ttctcgacct caggcaccag accaaggcaa
    72901 tcaccaaagt caagtgccta acgccaagcc tcaaacggac aagacggaca ctcctaacgt
    72961 cccagcccct ccacagaaca ctcctaacgc cccagccatc ccacgggaca ccccaaaagt
    73021 gcctgaggct ggtggtcaga gtggccccgc tgggaacgct gaggagaaag ctcctgactc
    73081 tggacctaaa gagtctgatc aaagctcgtc taaagagtcc ccatccgttg gcgaagacac
    73141 gacccctaat cagccagatg tccttgtagg tggtcaaagt gagccaattg atatcaccga
    73201 agacacaatc actgacgctc ctccgacagt atctgggcac aacgcatcaa cacagcccca
    73261 atctgtggtc gaagacccag cacctcagcg cccagatgtc cttgtaggtg gtcaaagcga
    73321 gccaatcgat atcacccaag atacccaacc gggcatgtca ggctctaatg acgctaccgt
    73381 tatcaatgaa gatacaaaac caaaacgcgt cttccacttt gataacaaag agccacaagc
    73441 atcagacaaa gcggcagagc aaaaacttgc tcctcatgat agccacacaa cccctcaagc
    73501 ttcagatgat acagcagccc ctcacttgcc tgcatctgga gataagcctg aaaaagtgtt
    73561 tgcacttgct gccttgacaa tggtcgcagc tgcagggtta ctcagcaaaa aacgtcgcaa
    73621 caccgacaaa aactagtcgc tgttagacac aacgcatctc taaggccagt gcaaatgcac
    73681 tggccttagt taggttttta tcaaatagag ggtttttcat gacaattgct agcatttcgg
    73741 tgtaaaataa aggtaataac caacaaagga gcaacccatg acaaagcaag atcagttaat
    73801 tgttgaaaaa atggaacaaa cctatgagac ctttagccca aagctagcaa atctcataga
    73861 agccctagat gcctttaaag agcattatga ggaatatgcc acacttagaa atttttacag
    73921 tagtgacgaa tggtttcggc ttgcaaacca accttgggat gatatcccgt gcggtgtcct
    73981 atctgaagac ctcctctttg atatgatcgg tgaccataac caactactag ctgatatctt
    74041 agacttggcc cctatcatgt acaagcatat gtaaccatcg ctaacgtcac agataccacg
    74101 atgacaggac aaaaaaagct agccaatctc aaaaaaacag ataaaaaaca gataatcgtt
    74161 agaaaaacag tagatgcgtc tgttaaacta aaggtatcaa aacaaaagga gcatttcatc
    74221 atgaaattca aaaaagtatt agtcattcct gcattagcat tagcagcaac atgcttttta
    74281 acagcttgtg gcacaaaaaa agattctaaa aaagaagaag ttaaagaaat caaaatgtct
    74341 gacatcaaag acgacgcagt tagcaaaaaa acaaaagtgg ttgatggcga agaagttaca
    74401 gaatacacca caaaagatgg aaacgtgatt cagattcctg caggaaacga agaaggcatg
    74461 gaatcaaaag atgctggtgg atcaggcgct cctgctaaaa actaagggtt acaacaaaga
    74521 gcataaggtg actcgcaaac gttacgcatg acatgaggca gtctgcctaa gatggtaact
    74581 cacttatcat aatgcctaaa tagccaaaca cactaactcg caaatgtaca aaatcatata
    74641 cccgtgctta tgtgagcgaa cggttatatg atttttgttt tccaaaaaca agaaaagaac
    74701 gctaaaatag ccagtttgtc gtgtttcaag ctaccaaaaa ggaagtgcta aaatgaaaaa
    74761 aagatccatt atacctgtca tcttactgtt ggtcatcgga ttaatcgttg gtgttaagcg
    74821 tcatcatgac tagtaggtct tgctagtgac cgttcaaaag ggataacgtt ggtatggtat
    74881 aaccataaaa atcgtataaa aagaaaaaat agctattgag gagaaagtat gtttcagtta
    74941 agaaaaaaaa tgacgcgcaa acaattagcc ttgttgagtg ctggagtgtt gacctgtgtg
    75001 gttggtggta gctacttgat aatgaaccat caacaacaag aaattgtctc tagtgtcaac
    75061 aaagtaaaag ccttaaccat aaaagaagcc atggaacaag gaaaagatat cagcttgacc
    75121 ttagctggcg aagtaacagc taacaacagc agcaaagtca aaatcgactc aagtaaagga
    75181 gaagtcaaag atgtctttgt caaaaaaggc gatgttgtca aagtaggaca acccttgttt
    75241 agctatgaaa cgtcacagcg gttaacggct caaagttcag aatttgatgt tcaaaccaaa
    75301 gccaatcaac tccaagttgc taaaaccaat gcagcattga agtgggaaac ctacaatcgc
    75361 aaggtcaatg aaatcaacac cctaaaatct cgctacaaca ctgcaccaga tgagagctta
    75421 ctagagcaaa ttcgcagcgc agaagacagt gtatcccaag cactaagcga tgccaaaaca
    75481 gcagatagcg atgtcaaaac cgctcaaatc gaactcgata aagctaatgc tactgccaca
    75541 acggaaaaag gtaaactaga gtatgacacc gttaagtcag acaccgcagg aaccattgtt
    75601 agcctaaata ctgatttgcc aaatcaatca aaatccaaaa aagaaaatga aacttttatg
    75661 gaaattatcg acaaatcaaa aatgttagtc aaaggtaaca tcagtgaatt tgaccgtgac
    75721 aagttaaaaa tcggtcaaaa agtcgaagtg attgaccgca aagacaactc taaaaaatgg
    75781 actggaaaag taacccaagt tggcaacctc aaagcagagg aaaaaggcca aggtcaaggc
    75841 caaggcggca atgaccaaca agacaatcca aaccaagcaa aattccctta tgttattgaa
    75901 cttgaccaat cagacaagca gccactcatt ggctcacaca cctatgttaa tgtgctcaac
    75961 aatgttccag aagctggcaa gatcgtattg aaagaaacct ttacaatggc agaaaatgga
    76021 aaaacctatg tgtggaaagt tgataaaaac aaggtcaaaa aacaagaaat taagactaag
    76081 cccttctcaa aaggttatgt tgaggtgaca agtggcttga ctatgcaaga taagattgct
    76141 cagccgcttc ctggcatgaa agacggtatg gaggtaggaa gtattgttaa accttaaaga
    76201 tattcgaaaa agctatcatc ttgggactga agaatttgcg attttaaaag gaatcgattt
    76261 agaagttaac gagggtgact ttttagccat catgggacca tcaggttcgg gaaagtcaac
    76321 attgatgaat atcattgggt gtttagataa gcctggctct ggctcatatg ccattgaagg
    76381 cagagacgtg tcatccttat ctgataatga acttgctgat ttgcgtaatc aaaaaatcgg
    76441 ctttgttttt caaaatttta acctgatgcc caagctaaca gcttgtcaaa atgtcgaatt
    76501 gcccttgact tatatgaatg ttcctaaaaa agagcgtcgc aaacgagccc tagagatgtt
    76561 aaagctagta ggattagaag aacgtagtga atttaaaccg atggagctat ctggtgggca
    76621 aaaacagcgt gtagcgattg caagagcttt agtcactaac ccgagtttta tccttggtga
    76681 tgagccaaca ggtgcactag acacaaaaac cagcgtccaa atcatggacc tatttaaaca
    76741 attcaatgat aacggcaaaa cgattattat catcacacac gagcctgaag tagctgcctt
    76801 atgcaaaaag acggtgatcc taagagatgg taatatagaa cattccgata tagagtaaag
    76861 ggggaaaata atggaagata ttattgcagc tttaagctct atattatcac acaagatgcg
    76921 gtcaattttg acaatgctag ggattattat cggtattggt gccattatcg caatcttttc
    76981 aatcatcgaa ggtaataccg aaaataccaa aagacagttg attggtggca gcaataacac
    77041 tattaacatt gtgtttaaca aaaaaagtag tattgaccct aaatttccag acaagtcaaa
    77101 tgctaaaaaa ccagactatc ttccttttat ggctgaagaa gagcttagca aaatacagca
    77161 agtcaaaggc gtcaaaaatg ccctgatctc atatggtatt gatgacaaag tctaccatct
    77221 aggccaaaaa tcatctgcaa agatttctgc catcacaaaa aacgtagctg aagtgagacg
    77281 catgacattt attaaaggca gtgacttttc agacaaagac tttattgacc aaaaacaggt
    77341 gatttacctt gaaaaaagct tgtatgagtc actatttcca aaagacgatg gtcttggaaa
    77401 atttgtcgaa gtgatgggaa atcccttcag ggtcattgga gtgtttgaat caaaagaaca
    77461 aagtggcctc acaagtggga ctgagaaaat tgcttatatc ccgctacatc agtggtataa
    77521 tattaatggt gtagtggatg cgacacctga gatcacgatc cagacctatc gcgcagatga
    77581 cctcaaacct gtagcaaagc gtgtcagtga tatgctcaat caaacgatcc ctaaatcaga
    77641 ttatatgttt ggtgtcatga accttaaaga atttgaacgc caactagaca atctaaacaa
    77701 atctaatttt gtgttattag ctggtattgc tagcatctct cttattgtag gtggtattgg
    77761 tgtgatgaac attatgctag tatcagttac cgaaagaacg agagaaattg ggatcaaaaa
    77821 agcgcttggc gctagacgta agcttatttt aaaacaattt ttaattgaag cggtcattct
    77881 aaccttgcta ggtggtgtga taggggttat ttcagggatg gtatcaggat tgatcatcac
    77941 aagatcactc gagtatccct atatcctatc cttgttctca gttgtcttga gtttagcgtt
    78001 ttgttgtatt atagggattg tctttggact attaccagcc attaaagcgt ctaagctaga
    78061 cccaattgaa gcattgcgat ttgaataatc aaccaaacaa gcataaaagt caaaaaggat
    78121 gaccctttga tgtcatcctt agctgcttga tacactaaac gccaatctag aaagggaagt
    78181 tatgtttaaa atattagtag ttgaagatga tgataccatc agtcaagtga tttgtgagtt
    78241 tttaaaagcg aataactatg atccagattg tgtatttgat ggccaagctg ccttagacaa
    78301 gtggcagaca acgtcttatg atctgattat tttagacatc atgctccctt ccttaagtgg
    78361 cttagaagtg ctaaaaacaa ttcgaaagac atcagatgtc cctattatta tgctaacggc
    78421 attagatgac gagtacacac agcttgtaag cttcaaccat ttgattagtg attatgtgac
    78481 caaaccattt tcaccactca ttttaatcaa acgtatcgaa aatgtattac gcgtctctac
    78541 tccagatgaa aagcgccaaa tcggagactt acttgttgat gagaccgaac atagcgtcta
    78601 ttggcaagga acattggtca aactaaccaa aaaagaatat gacattattg attatttagc
    78661 aaaacgtcac caaaaaattg tcaccagaga ccaattgatg gatgacatat ggggctattc
    78721 tgaactggac acgcgtgtcc ttgacaacca catcaagaac cttcgtaaaa aaatgacggg
    78781 tattcccctc aagacaatta caggcatggg ctatttattg ggagagcgtg agtgagacta
    78841 atcaaaaaaa cctttttggt catcaatggc ttaattattg tagtggttac ctctattttg
    78901 ttagtgcttt attttgcaat gccaatttat tacaccaaag tcaaagacaa agaagttaag
    78961 cgtgaatttg accaaacaag caagcaaatc aaaggcaaaa cggtaaccga gattagagat
    79021 atcctaacaa aaaaaatcaa caaagataat atttggtaca gcttagtaga cagtgataac
    79081 caactgctct atccttcctt gcagctgtta gacggcgtca ctgaaagcaa agacagtcaa
    79141 aatgttaata tcgtcaccac ctttgacaac tcttattcta atgttaaggt gatgagtcaa
    79201 aaagtaaccc tacgcgatgg aaaaaagatg acattgcttg ggcaatcttc acttcaaccc
    79261 gtaacagatg ctagcaaagt tctccttgac ctctacccgt cactattgat tttttcagtg
    79321 accgtaggga gtattgtcgc ctacttatat agtaggactt ctagccggcg tatccttagc
    79381 atgtcacaaa ccgccaaaaa aatggtcaac ctagaaccaa acttaacgtg taccattcac
    79441 ggcaaagatg aaatagcaat gttggctagt gatattaacc gtttgtatgc gagtctttca
    79501 acgagtatca aatccttgca aaaagagtat gaaaaagctt ctgattcaga aagagagaaa
    79561 tctgagtttt tacgcatgac atcgcacgag ctaaagacac caatcaccag tgttatcgga
    79621 atgattgatg gaatgctcta taatgttggt gactttgcag atcgtgacaa atatttgcga
    79681 aaatgccgag acgtccttga agggcaagcc caactggttc aatccatttt atctttatct
    79741 aagattgaaa ccctagcttc tcaaaatcaa gaactgtttt cactaaaaag cagcctagaa
    79801 gaagaaatgg aagtctttct cgtcttatca gaactaaaac acctcaaagt gactatcaat
    79861 ctcgaagaac aattcgtcaa agccaataaa gtatacctac taaaggcgat taaaaatatt
    79921 attgataatg cctttcacta taccaaacca ggcggccaag tgatgattca actaaaagac
    79981 aaccaactag tgattaaaaa tgaagcagag acattattga cacaacagca gatgaaacag
    80041 ttattccaac cgttttatcg accagattat agtcgtaaca ggaaagacgg tggtacagga
    80101 ttggggctgt ttatcaccca ccagattctt gatcagcatc atctggctta tcgctttgtt
    80161 gttcttgatc aaagatggat ggtatttacg attgattttc catcccatca tgacgattga
    80221 tccacactag taggacgaca aaagtcatca atcattaacc aagccttgac ctttacccat
    80281 cattgtttag gcaagtataa aaaagaggag agaaatcata tatgaagaaa aggaaattgt
    80341 tagcagtaac actattaagt accatactct taaacagtgc agtgccatta gttgttgctg
    80401 acacctcctt gcgtaataac acatcatcca ctgatcagcc tactacagca gatactgata
    80461 cggatgacga gagtgaaaca ccaaaaaaag acaaaaaaag caaggaaaca gcgtcgcagc
    80521 acgacaccca aaaagaccat aagtcatcac acactcaccc aacccctcct tcaaatgata
    80581 ctaagcagac cgatcaggca tcatctgaag ctactgacaa accaaataaa gacaaaaaca
    80641 acaccaatca atcagacagc agtgatcagt ccaccccatc tcccaaagac cagtcgtctc
    80701 aaaaagagtc acaaaacaaa gacggccgat ctaccccatc acctgatcaa caaaaagatc
    80761 agacacctga taaaacacca gaaaaatcag ctgataaaac ccctgataaa gcccctgaaa
    80821 aaggaccaga aaaatcagct aaaaaaacac cagagccaaa tcgtgacgct ccaaacccca
    80881 tccaacctcc tttagcagca gcagctcctg tctttgcacc ttggagagaa agtgacaaag
    80941 acctgagcaa gctaaaacca agcagtcgct catcagcggc ttacgtgaga cactggacag
    81001 gtgagtctgc ctacactcac aacctgttgt cacgccgtta tgggattact gctgaacagc
    81061 tagatggttt tttgaacagt ctaggtattc actatgataa agaacgctta aacgggaagc
    81121 gtttattaga atgggaaaaa ctaacaggac tagacgttcg agctatcgta gctattgcaa
    81181 tggcagaaag ctcactaggt actcagggag ttgctaaaga aaaaggagcc aatatgtttg
    81241 gttatggcgc ctttgacttc aatccaaaca atgccaaaaa atacagcgat gaggttgcta
    81301 ttcgtcacat ggtagaagac accatcattg ccaacaaaaa ccaaaccttt gaaagacaag
    81361 acctcaaagc aaaaaaatgg tcactaggcc agttggatac cttgattgat ggtggggttt
    81421 actttacaga tacaagtggc agcgggcaaa gacgagcaga tatcatgacc aaactagacc
    81481 aatggataga tgatcatgga agcacacctg agattccaga acatctcaga ataacttccg
    81541 ggacacaatt tagcgaagtg cccgtaggtt ataaaagaag tcagccacaa aacgttttga
    81601 cctacaagtc agagacctac agctttggcc aatgcacctg gtacgcctat aatcgtgtca
    81661 aagagctagg ttatcaagtc gacaggtaca tgggtaacgg tggcgactgg cagcgcaagc
    81721 caggttttgt gaccacccat aaacctaaag tgggctatgt cgtctcattt gcaccaggcc
    81781 aagcaggagc agatgcaacc tatggtcacg ttgctgttgt agagcaaatc aaagaagatg
    81841 gttctatctt aatttcagag tcaaatgtta tgggactagg taccatttcc tatcggacgt
    81901 tcacagctga gcaggctagt ttgttgacct atgtcgtagg ggacaaactc ccacgaccat
    81961 aaccccacaa ccaagaagct acctgcctgt tgaccaatct caaaaagaga cagcgtcaac
    82021 ttagaatgag gttcatcaga tgataaagaa agtgaccacc ccgagtcaaa aaacaaaaaa
    82081 acgtgttcgt aatggctacc tcctaaaact aggtacagcc tgtttactct taagtatact
    82141 cagttatggc attggtcttt tgggccagcc tagcatggaa aatacgttta tgggaatagc
    82201 gagtgttgcc atgttaggaa gtgtctgttt ctttattatc tttgctctaa accgtatctt
    82261 tgacgcatta gaggacaatt tgcgagatta gagtaatagg tcaaataatc ttccaataat
    82321 ttagagcaca agctaagtta ttggaagttt ttttgtcttt tgagagccat gatgccatca
    82381 aaaagccaaa cactccttat gatgtgagag tcacatggct aaattaaaag caaaatagac
    82441 cccaaagccc tgttttctca aaacagccaa caaaggaaga caagttaacc agttcataaa
    82501 aaacatcgta gaaacgtttt caagagctaa tgttggagta aattgactga agtatgatag
    82561 aatttttaat gaatgtgaca ataatatcac agataaaaac caaaaacagc aaaaataatt
    82621 aaattgaata taaaaaagtt aattaagtga g
//
LOCUS       DAUGSW010000006        71315 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUGSW010000006 DAUGSW010000000
VERSION     DAUGSW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71315
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.006"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            213..836
                     /locus_tag="VIB18_000453"
     CDS             213..836
                     /locus_tag="VIB18_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8765483.1"
                     /translation="MTIEIFNVTKKFSSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDNGKVLVDEQDIWKIKERTFFKNIIGYVFQNYSLIENKTVYDNLKLIN
                     KDKKKISAVLEKVGLSSDYLNQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDFIIDMKDIGSKK"
     gene            833..1324
                     /locus_tag="VIB18_000454"
     CDS             833..1324
                     /locus_tag="VIB18_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765484.1"
                     /translation="MKKKIYIGLIVIVGVFVVFLSGKQITQKETSNKPVVTLTVYTIS
                     SSDTQKWSKVKQFETKEAIYLVKVKETTSSEEVFSNIIADGMAVGFGVSEEDVKQFND
                     NLCSPVEDAKNNKLIGIEFINFSSVDKGFVVANFDYGKKAFNSQKTENKKLYKKLYEA
                     YKG"
     gene            1528..2058
                     /locus_tag="VIB18_000455"
     CDS             1528..2058
                     /locus_tag="VIB18_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEQ8765485.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            2107..2694
                     /locus_tag="VIB18_000456"
     CDS             2107..2694
                     /locus_tag="VIB18_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEQ8765486.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            2847..3575
                     /locus_tag="VIB18_000457"
     CDS             2847..3575
                     /locus_tag="VIB18_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8765487.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRPRKQDPQSLDFLMDISLSMKNQKAWKKRFITLIVCLTVETLLFVGGAYF
                     LQLTVWKYLLIPVFLLVLLGTLCWYYQNICYLCPSCHQTFEAKWTEFALAGHTPRTRK
                     LTCSHCHQKSYCLELAKEDIVSRG"
     gene            complement(3632..3931)
                     /locus_tag="VIB18_000458"
     CDS             complement(3632..3931)
                     /locus_tag="VIB18_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEQ8765488.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFASKLPF"
     gene            complement(4124..4498)
                     /locus_tag="VIB18_000459"
     CDS             complement(4124..4498)
                     /locus_tag="VIB18_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8765489.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            4668..4889
                     /locus_tag="VIB18_000460"
     CDS             4668..4889
                     /locus_tag="VIB18_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8765490.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(4969..7251)
                     /locus_tag="VIB18_000461"
     CDS             complement(4969..7251)
                     /locus_tag="VIB18_000461"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEQ8765491.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVAYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIVNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(7273..7932)
                     /locus_tag="VIB18_000462"
     CDS             complement(7273..7932)
                     /locus_tag="VIB18_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8765492.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            8098..9294
                     /locus_tag="VIB18_000463"
     CDS             8098..9294
                     /locus_tag="VIB18_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8765493.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMVIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLVMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVLS"
     gene            9796..10644
                     /locus_tag="VIB18_000464"
     CDS             9796..10644
                     /locus_tag="VIB18_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8765494.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(10979..11875)
                     /locus_tag="VIB18_000465"
     CDS             complement(10979..11875)
                     /locus_tag="VIB18_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEQ8765495.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            12173..12925
                     /locus_tag="VIB18_000466"
     CDS             12173..12925
                     /locus_tag="VIB18_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEQ8765496.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            12910..13860
                     /locus_tag="VIB18_000467"
     CDS             12910..13860
                     /locus_tag="VIB18_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEQ8765497.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADTTVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSDHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLHNALKHDLTTPVS"
     gene            complement(14040..16367)
                     /gene="pflB"
                     /locus_tag="VIB18_000468"
     CDS             complement(14040..16367)
                     /gene="pflB"
                     /locus_tag="VIB18_000468"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEQ8765498.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISNK"
     gene            16576..17670
                     /gene="dinB"
                     /locus_tag="VIB18_000469"
     CDS             16576..17670
                     /gene="dinB"
                     /locus_tag="VIB18_000469"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEQ8765499.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(17763..18245)
                     /locus_tag="VIB18_000470"
     CDS             complement(17763..18245)
                     /locus_tag="VIB18_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765500.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVFAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(18336..20789)
                     /locus_tag="VIB18_000471"
     CDS             complement(18336..20789)
                     /locus_tag="VIB18_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEQ8765501.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLNRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTYFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNANPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(20847..21440)
                     /gene="lepB"
                     /locus_tag="VIB18_000472"
     CDS             complement(20847..21440)
                     /gene="lepB"
                     /locus_tag="VIB18_000472"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8765502.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(21451..22353)
                     /locus_tag="VIB18_000473"
     CDS             complement(21451..22353)
                     /locus_tag="VIB18_000473"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEQ8765503.1"
                     /translation="MNTLVLKIDAILSKHLKKQLASYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            22510..22818
                     /locus_tag="VIB18_000474"
     CDS             22510..22818
                     /locus_tag="VIB18_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765504.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            22821..23366
                     /locus_tag="VIB18_000475"
     CDS             22821..23366
                     /locus_tag="VIB18_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEQ8765505.1"
                     /translation="MLSLLIVLILTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            23515..25854
                     /locus_tag="VIB18_000476"
     CDS             23515..25854
                     /locus_tag="VIB18_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEQ8765506.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSEM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG"
     gene            25858..26358
                     /locus_tag="VIB18_000477"
     CDS             25858..26358
                     /locus_tag="VIB18_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8765507.1"
                     /translation="MESYEHFYAKLSQPFRKTPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSALLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            26439..26753
                     /gene="trxA"
                     /locus_tag="VIB18_000478"
     CDS             26439..26753
                     /gene="trxA"
                     /locus_tag="VIB18_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEQ8765508.1"
                     /translation="MALEVTDATFVEETEEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(26805..27393)
                     /locus_tag="VIB18_000479"
                     /pseudo
     CDS             complement(26805..27393)
                     /locus_tag="VIB18_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(27469..28593)
                     /gene="mutY"
                     /locus_tag="VIB18_000480"
     CDS             complement(27469..28593)
                     /gene="mutY"
                     /locus_tag="VIB18_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEQ8765509.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPRPMRIQAFVIRNQDGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            28791..29084
                     /locus_tag="VIB18_000481"
     CDS             28791..29084
                     /locus_tag="VIB18_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765510.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            29257..29547
                     /locus_tag="VIB18_000482"
     CDS             29257..29547
                     /locus_tag="VIB18_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEQ8765511.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            29569..30060
                     /locus_tag="VIB18_000483"
     CDS             29569..30060
                     /locus_tag="VIB18_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8765512.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            30225..30464
                     /locus_tag="VIB18_000484"
     CDS             30225..30464
                     /locus_tag="VIB18_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEQ8765513.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(30597..31253)
                     /locus_tag="VIB18_000485"
     CDS             complement(30597..31253)
                     /locus_tag="VIB18_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEQ8765514.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(31386..32330)
                     /locus_tag="VIB18_000486"
     CDS             complement(31386..32330)
                     /locus_tag="VIB18_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEQ8765515.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            32533..35361
                     /gene="uvrA"
                     /locus_tag="VIB18_000487"
     CDS             32533..35361
                     /gene="uvrA"
                     /locus_tag="VIB18_000487"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEQ8765516.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
                     GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSIGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            35476..36549
                     /locus_tag="VIB18_000488"
     CDS             35476..36549
                     /locus_tag="VIB18_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8765517.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDASEIETIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGATGTSFDIIAASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITETGCQVLTLAPKELIVL"
     gene            36584..37045
                     /locus_tag="VIB18_000489"
     CDS             36584..37045
                     /locus_tag="VIB18_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEQ8765518.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            37141..37698
                     /gene="efp"
                     /locus_tag="VIB18_000490"
     CDS             37141..37698
                     /gene="efp"
                     /locus_tag="VIB18_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEQ8765519.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            37744..38133
                     /locus_tag="VIB18_000491"
     CDS             37744..38133
                     /locus_tag="VIB18_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8765520.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            38126..38578
                     /gene="nusB"
                     /locus_tag="VIB18_000492"
     CDS             38126..38578
                     /gene="nusB"
                     /locus_tag="VIB18_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEQ8765521.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(38719..39684)
                     /locus_tag="VIB18_000493"
     CDS             complement(38719..39684)
                     /locus_tag="VIB18_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8765522.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEILKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(39689..41128)
                     /locus_tag="VIB18_000494"
     CDS             complement(39689..41128)
                     /locus_tag="VIB18_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEQ8765523.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYNYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            41370..43253
                     /locus_tag="VIB18_000495"
     CDS             41370..43253
                     /locus_tag="VIB18_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8765524.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSILGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVARLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDITMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            43484..46495
                     /locus_tag="VIB18_000496"
     CDS             43484..46495
                     /locus_tag="VIB18_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8765525.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKEKVPEKVKEILAKAQQADKQAQELTKMKIPEK
                     IPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLFW
                     KELGTKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVD
                     EYVYKYNLDGLDVDVEHDSIPKVNGEASDENLKRSIDVFEEIGKLIGPKGVDKSRLFI
                     MDSTYMADKNPLIERGAPYIDLLLVQVYGARGEQGEFQNDTKLVTETPEERWQGYSKY
                     IRPEQYMIGFSFYEERAGSGNLWYDINSRKDEDTANGINTDITGTRAERYARWQPKTG
                     GIKGGIFSYAIDRDGVAHQPKQIAEKDKQNVKNNQPQIPEITDNIFHSDYSVSKALKT
                     VMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNK
                     FKKLAQLDLIGLSRITKLDRSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLK
                     VSGLTGLKELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLS
                     TVSNHVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVAEGNIDLQSQLLFGTVTNQGT
                     LINSEADYKAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATD
                     KEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFDG
                     QLGSETDNISLGWDSKQSIIFKLKEDGLIKHWRFFNDSARNPETTNKPIQEASLQIFN
                     IKDYNLDNLLENPNKFDDEKYWITVDTYSAQGERATAFSNTLNNITSKYWRVVFDTKG
                     DRYSSPVVPELQILGYPLPNADTIMKTVTTAKELSQQKDKFSQKMLDELKIKEMALET
                     SLNSKIFDVTAINANAGVLKDCIEKRQLLKK"
     gene            46759..47643
                     /locus_tag="VIB18_000497"
     CDS             46759..47643
                     /locus_tag="VIB18_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8765526.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFLTTTPEETIART
                     IAYFKAFEADLAGIAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     LHPDDMAKGFLGVCPFHKGCLEGMSAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            47738..48691
                     /gene="manA"
                     /locus_tag="VIB18_000498"
     CDS             47738..48691
                     /gene="manA"
                     /locus_tag="VIB18_000498"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEQ8765527.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
     gene            48825..51344
                     /gene="secA"
                     /locus_tag="VIB18_000499"
     CDS             48825..51344
                     /gene="secA"
                     /locus_tag="VIB18_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEQ8765528.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
     gene            51460..51816
                     /locus_tag="VIB18_000500"
     CDS             51460..51816
                     /locus_tag="VIB18_000500"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEQ8765529.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            51813..52913
                     /locus_tag="VIB18_000501"
     CDS             51813..52913
                     /locus_tag="VIB18_000501"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEQ8765530.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELKLAITRQVT
                     VTVASLEWLAMAKQEWPDLKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHTSNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            53000..54529
                     /locus_tag="VIB18_000502"
     CDS             53000..54529
                     /locus_tag="VIB18_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8765531.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSKQLPEARTPI
                     QSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKS
                     TGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAF
                     DLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFT
                     DTTGSGKRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLG
                     YQASGYSWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKVGYALSKTPKVGYAISFAP
                     GQAGADGTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSK
                     N"
     gene            55021..58848
                     /gene="shr"
                     /locus_tag="VIB18_000503"
     CDS             55021..58848
                     /gene="shr"
                     /locus_tag="VIB18_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ8765532.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKPVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDITITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLDDTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHLHQKDLVEKGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            59047..59931
                     /locus_tag="VIB18_000504"
     CDS             59047..59931
                     /locus_tag="VIB18_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEQ8765533.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQDVKDNQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKFLPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKRKKNDKTM"
     gene            59915..60799
                     /gene="isdE"
                     /locus_tag="VIB18_000505"
     CDS             59915..60799
                     /gene="isdE"
                     /locus_tag="VIB18_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEQ8765534.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHP"
     gene            60801..61823
                     /locus_tag="VIB18_000506"
     CDS             60801..61823
                     /locus_tag="VIB18_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8765535.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            61820..62656
                     /locus_tag="VIB18_000507"
     CDS             61820..62656
                     /locus_tag="VIB18_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765536.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     TMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            62653..64416
                     /locus_tag="VIB18_000508"
     CDS             62653..64416
                     /locus_tag="VIB18_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEQ8765537.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDLQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLSTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            64409..66079
                     /locus_tag="VIB18_000509"
     CDS             64409..66079
                     /locus_tag="VIB18_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765538.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            66076..66669
                     /locus_tag="VIB18_000510"
     CDS             66076..66669
                     /locus_tag="VIB18_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEQ8765539.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSVFAHYLLKKHFIKSGLLS"
     gene            66666..67346
                     /locus_tag="VIB18_000511"
     CDS             66666..67346
                     /locus_tag="VIB18_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8765540.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            67283..68737
                     /locus_tag="VIB18_000512"
     CDS             67283..68737
                     /locus_tag="VIB18_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765541.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVSTC
                     QIASGQFIVLCGPSGSGKSTFLKFLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQNLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            69112..71127
                     /gene="recG"
                     /locus_tag="VIB18_000513"
     CDS             69112..71127
                     /gene="recG"
                     /locus_tag="VIB18_000513"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEQ8765542.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENRSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYTSLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITVFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     HKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD"
BASE COUNT        22018 a        12413 c        14893 g        21991 t
ORIGIN      
        1 ttaggcctct caaaaacacg catagcaatt tcgagtctca aatattttat tatgactatt
       61 gcaatagtta taatatgtac atttatggtg acagagcaga ttgagttatt atatattggt
      121 attgcttcat tagtggtttt aattctttcg acagtaatga gttttagaaa attatcaaaa
      181 aaatacactc aaattttaaa aggagatgaa caatgacaat tgaaattttc aacgttacaa
      241 aaaaattcag ctcaaaaaaa atatttacag atttaaattt aacgtttgaa gctggaaaaa
      301 gctatgcctt gattggaggt tctggctctg gtaaaagtac tctgcttaac attataggaa
      361 gactagaaaa aattgataac gggaaagttt tagttgacga acaagatatt tggaaaataa
      421 aagaaagaac tttctttaaa aatattatcg ggtatgtatt ccagaattat tctttaatag
      481 aaaacaaaac tgtatatgat aatttgaaac tcatcaataa agacaaaaaa aaaatatctg
      541 ctgtacttga aaaagtaggg ctctctagtg actatttaaa tcaaaaaata tatgaattgt
      601 ctggagggca ggctcagcgt gtagctattg caagaatgtt aatgaagcca cgtaaaataa
      661 ttttagcaga tgagccaaca ggagctttgg atggtgaaat tggaaaagaa attattaatt
      721 tgttgttgag cgaaacagcc gaaaataaat acgttattat agcaactcat gatccagctg
      781 tatataataa ggttgatttt ataattgata tgaaagatat agggagtaag aaatgaaaaa
      841 gaaaatttat attggcttga ttgtcattgt tggagttttt gtagtgttct tgtctggaaa
      901 acaaatcaca caaaaagaaa cttcaaataa gcctgtggtg accctaacag tttataccat
      961 ctcctctagt gatacccaaa aatggagtaa agtaaagcag tttgaaacga aagaagcaat
     1021 atacctagta aaggtaaaag aaactacctc ttcagaagaa gtcttttcaa acatcattgc
     1081 agatggaatg gcagttggtt ttggagttag tgaagaagac gttaaacagt ttaacgataa
     1141 tttatgtagc ccggtagaag atgctaagaa taataaatta attggaatag aattcatcaa
     1201 tttttctagt gttgataagg ggtttgtggt tgcaaatttt gactacggca aaaaagcgtt
     1261 taattctcag aaaacagaaa ataaaaaatt atataaaaag ctctatgaag cgtataaagg
     1321 atagctattt atagtttctt gagagtgata ccacttctga ataataaatg aactaacctg
     1381 gcataccgtt ttctattcat ctaacaatgt tttcaagaaa taattgatgc ctttagcacg
     1441 actgaaatga ggtcaaattg acagaatact cctattatgg tactattttt aataagaata
     1501 ttcagtgata gtgataaaga ggaaaatatg ggaattgaaa agacagttag tgaactagct
     1561 gatattttgg gagtgagtcg tcaggccgtc aataatcgtg ttaagtcttt acccgaagaa
     1621 gatcttgaca aaaatgaaaa aggcgttact gtggttaagc gcagtggtct tgttaagctg
     1681 gaagagatct ataaaaaaac aatttttgac gatgagccta tcagtgaaga aacgaaacaa
     1741 cgtgagcttt tagagattct tgtggatgag aagaacactg aaatcacgcg cctttatgag
     1801 caactcaaag ccaaagatgc tcaacttgcc tcaaaagatg agcaaatgcg tgttaaagac
     1861 gtgcagatcg ctgaaaaaga taaacaattg gatcagcagc aacaattaac tgctaaagcc
     1921 atggctgata aagaaaccct aaaactagaa ttggaagaag ctaaagcaga agccaaccaa
     1981 gctcgcttac aagtcgaaga agttcaggct gaagttggcc ctaaaaaagg ctttttaacc
     2041 cgcttgtttg cgaaataatc acaaaaaatg acgaaggccc tatcagggtc ttttttggag
     2101 gaaaacatga aacacttaga tacttatatt gcctttgatt tagaatttaa cactgtcaat
     2161 gacgttagtc atgtcattca agtatcagca gtcaaatatg accaccataa agaagttgac
     2221 agctttgaca cctatgttta cacagatgtt cccttacaga gctttatcaa tggcctaaca
     2281 ggaatcacat ctgacaagat tgctgcggca ccaaaagtag aggaggttat ggctgcgttt
     2341 aaaaattttg tgggagagtt accactgatt ggttataatg ctcaaaaatc tgacctgcct
     2401 attctagctg aaaatggctt ggatttaagg gaccaatacc agattgacct ctttgatgaa
     2461 gcttacgata gacgtagcgc agacttaaat gggattgcta accttcgtct gcaaacagtg
     2521 gcaacctttt taggcattaa gggtcgaggt cataatagct tagaagatgc cagaatgaca
     2581 gcagcaatct ataagtcttt tttagaaaca gatacaaaca aagcatatct cagccagcaa
     2641 gaagaggtaa ccacagataa ccctttcgca gctttgggag acttttttga ctaagggctc
     2701 tgctatttct aaaaaataac aaaaattcct agggttagct cttgcttgta acgctaggtc
     2761 atgtgataag ataggggcat atcaagaggg agtcgagtgc acacgaatcg tttttgatca
     2821 ctaaatgata gaaagaaggt gtggaaatgt ctcaattcta ttcgactgga gaattggcca
     2881 acttagctgg cgtttctatt cgaactgtcc aatactatga ccaacgtggg attttgattc
     2941 cgacagcttt gacagaaggt ggacggcgac tctatacgga ttctgattta gaacaattac
     3001 gcatgatttg ctttctgcgc gatttgggat tttccattga gcagattcgc aaagtcttag
     3061 cagaggaaaa tgcagcccag gtgctggaat tgcttctagt tgatcatatt gcgactgcca
     3121 aggaagactt ggccgcaaaa gagcaacaag ttgacatagc tgtcaagata cttgacagac
     3181 ctcgaaaaca agacccccag tcactagatt ttctgatgga catttcgctt agcatgaaaa
     3241 atcaaaaagc ttggaaaaaa cgctttatta ctttaattgt ctgtttgaca gtggaaactc
     3301 tactttttgt gggtggagcc tattttctcc aattgacagt ctggaaatat ttattaatcc
     3361 cggtgttcct tttagtctta ctaggaacct tatgctggta ttaccaaaat atctgttatc
     3421 tttgtccttc ttgtcatcaa acatttgaag caaaatggac agaatttgcc cttgcaggcc
     3481 atacaccacg aactagaaag ttaacctgct cccattgcca tcaaaaatcg tattgcttgg
     3541 aactggcaaa agaggacatt gtctcaagag gataagcact tactcataaa aaaactagcc
     3601 tgagatcctt ctcaagctag tttttgtttt tttagaatgg taatttacta gcaaaagcgc
     3661 ctaatgtttt cttagttgct tcatcaattt gcgtaagggc atcattaatg gcttgagtgg
     3721 tcatatcttg aagcgtttct acatcttcag gatctacaac agcttctttg aagtcaatcc
     3781 caaccaattt tttatcaccc gtgaaagtgg cagtgacaag gtcttgagct gattttccag
     3841 taaattgcat agcagccaaa tccgcctgct tttgctccat ttgtttctga agcttttgtg
     3901 cttgcttcat catgttttgc atgttcatca taagactata ctctccttaa tttaatacta
     3961 actattataa cacataaaaa gaggcaataa aaacaatgtc agttagtaga ctagcctgta
     4021 tcagtaagaa agtcgctatg gataagatgg attagcagca agggtctggc taatgacaga
     4081 ataagtctag aaatggacta tttttgtcat agactagtcc gacttagtgg ttatctaatt
     4141 cacgatcttc tttagcttgt tgttctaaaa gaatttgtgc gaagtcaacc cacttagtgt
     4201 agttattttc ggataattgt tctgaaatca tcgctaactc tcgttgtggc aactgataag
     4261 agactccctt actttctaag gttaaatctt cttccattag ggcggttaaa ctaacatcaa
     4321 agatagcagc aatatcactt aatagaccag actttggagt atattttcct ttttcccact
     4381 cactgattga agaagagctt tttcgtccta ggagattagc aagttctaat tgttccatgt
     4441 tcttttttaa tctaaggtac tttaaattac ttgcaaaaaa agttttcttg gcggacatat
     4501 ttttctcctt ttctttatat aaaatatgat accataaaag aggttaaagc aaaaggtatc
     4561 gtaaaagatg gtctaaaaac tctctaaaaa cttgacttca taaaaaccga agtttataat
     4621 aaacttaaca tgattaacta atctcatttt agtgtggagg gaaaattgtg accaaatcaa
     4681 ctttaaaaga gttaagaaca acaaagaaaa tgacacagca ggaattgtct cacttaacag
     4741 gtatttctgt cagaacgatt gctaggtatg aaaaagatac taaaaagcta aggcgagcaa
     4801 aatatgagaa gctaaaaggt attgcacaag cattagcggt ttccgttgat gatatttttt
     4861 taggaataga ttcggaattt atgaactaag acgatcgttt tctgtttgct attagtaaga
     4921 ccaattaaca aaaaagtgct tagttatatt gctaagcact tttctttgtt aatttgatgc
     4981 tattggcaca atcaattgag actgactgag atcgatagtt aaagcatagt tgctgttgtc
     5041 acggacagta tgttcaaaat cggttgtgta taagatgact cgaagggtat ctcctttttc
     5101 tagatgatag atagttggtt gcaaaggaag tctaacagtc atccatttat tattaggaat
     5161 agtttcaatt gacgacaaat tattgcgatt ttgtaaattc atgaaacctt tcgaaataac
     5221 acggtaagaa tcttctctaa atggtagctc tttaaggggt tctctagaga aattttgccc
     5281 attgtcaata cttgattgag tgagagcaat aggaagatcg cccaagcgtt ttttcttacc
     5341 atagtcaagg atttgtgcag atagaagtcc tttattttca cttgatttca cttttaactg
     5401 taggacaatt tcaccgttaa taggtaagtc ctcttccagt aaaatatcaa ccagggcttg
     5461 attggccttg ccttcaaaga gagctgcttt gaacgcacgg aaatctttac cgtaagcttt
     5521 aaattcatct tcaccatagt gattatcaat taaaagcagt tcctgaccga ggtcaagctc
     5581 tttgatggtt gaggttccaa agactttacg ctcctgccag ttttgtgggc aggtgttatc
     5641 ctgccagatc atttcaggaa ggctaaaatc attagctagg cctaagagtt tttgacataa
     5701 aagggcattc atgctttcgc gaaaatcaat ggattgccaa ttatgcatgt aaacatgctc
     5761 accttgatgt aaaaagaggt gcttgttgat tgtggaagga agcgcattga caatctcata
     5821 gacctgtctt ggtttgacat tccagtcttg taagccatga gtataaacga catcacactt
     5881 tatttgatga gcatttttta agtaattgcg gtcgtgccaa aattgattat aatcaccaga
     5941 ttgtcggtct aacgcctgag actgttggtt tagcaattct tgataacgat cattatggcg
     6001 aagataatcg ccagccaata aattacgcga gtaagtgagc tcagttagga catctagatc
     6061 ctctccagga tagccaccag gactacagac taagccattt tcgcggtagt agttgtacca
     6121 agaagaaata gctgattctg caataatcat ggctaatccg tctacgcctg tagtggctaa
     6181 accagtagac atagttccca agtaggactt tccagtcgta caaactagac catttgccca
     6241 atcagctctc acttggtggg tttttgagtg gctggtgtag gctgtggctc ttccatttag
     6301 ccaatcaata acggctttaa agctttcaat ttgagcatag tctccactcg tcataaagcc
     6361 agtggaacca gcagttccca cacctgaaac atagatatta gcaaacccac gtgcgaggaa
     6421 ataatcgttg aggctatagg agttaatgta gctaaagctt tctagatttt gacctatagg
     6481 aagtttgcaa ggctgtgtct caagaggaat aaaatccctg tcttcgacag tgatttgtct
     6541 ccttttttta acgactaact ctttttccat acgataaagt tttttgtcgt tggctacttc
     6601 attgatacct tgatggtatg gactaggtgt catcaaagtt ggtaatggtt tttgagattg
     6661 aggacgaatg atattaacct taataagatc aagttggcca tcttgatcgg tatcaagagg
     6721 tgcttcaacg taagcaactt ctcgaatcag ctgtgacgtg tcaaaggtag ctaatgattt
     6781 accgttgaag aagtggtaat cattgtccat agtaagcatt ccttggctga ccaaatcatc
     6841 aatcagggtc atgccagact tacaacgggt cgctaataag tggtggatat gcttgataat
     6901 ttctgtttcg tcaaagtgga taggaaaggc cagtttatca aggaaagcat cggcctctgt
     6961 aaaatcaact ccaggaataa agccaaggac ttgcagggcc agtaaatcaa aaacctcttt
     7021 ggataactct tgctctgatt gaaaaaagct caatgcgtcc atgtcatttt tggcgattag
     7081 atgacttaaa ggataatcac tatcagggta gtggaagaag agtttacgta aaaagctttc
     7141 taggttagct ttggcagttt tttgcagatc cagatcaaag cccaattctt ttaattcttc
     7201 agccgctctt tctagactag ttggaatata ggaaaattga ttatagcgca taggagtttc
     7261 ctttctagtg gcttagaaaa cgatattatc ttttaatttg tcaagattgg taatgataat
     7321 atgttgttta tcaatgcgaa tgatgttttt ttctttcaac tgttttagaa tacggctgac
     7381 gctgctagcg gtagaaatgc cacagaattt accgagttcc tcattagtaa tgacaaaatt
     7441 aattaaaatt tgaccatttg gtagttcttc gccaaatagg gtcattaagt catatatttg
     7501 agtagaaatg gcaccgatac ggccgttagt taacatacat tgcatttttt tcatggattt
     7561 ttgaagacga ttatggtaaa agtccttcac atatccttgt agttcaatat cttcgtttat
     7621 atcttttaaa aatgctgagc ggcgaacctt gtaaaaacta gctttctctg actcgatgcg
     7681 aacattataa ggctctccca tatcttttga ataaccagtg ttgagaacag aagtaatttc
     7741 aagtcctgta acatatctca aattaaattc cattccatat tttgaaagaa cactctgttt
     7801 cacaatgccg tcttttaaaa tataagtgaa gtcctcttcg agactttcaa aagtcaagta
     7861 cttgtgataa cttttttcaa tgataggaaa gttatgatta tcaatatacc gttgcaaaat
     7921 gtgatgattc acgcttttct ccaaatattc ttttaccaat gtataatttg tatcttcaag
     7981 agaaattaac atttgctaat gccctttgat agtaacactt atattatacc attgaaatat
     8041 attatattct gctttttttg taaaatgttt atgaaaatag agaggagttc attttcaatg
     8101 gaagaaaaat tgtttaacaa acattttgtg gccatcacag taataaactt tatagtctat
     8161 atggtctact atctttttac ggttattatt gcctttgtgg cgactagaga gctaggagct
     8221 cagactagcc aggcaggatt ggcaacaggg atttatattc tagggacttt attagcccgt
     8281 ttgatttttg gaaagcagtt ggaggtgttt ggtcgtcgtt tggttttaag aggaggtgct
     8341 attttttacc tcttaacgac cttagcctac ttttatatgc caacgattag catgatgtac
     8401 ttggttcgtt tcttgaacgg atttggttat ggtgtagtat caactgcgac aaataccatt
     8461 gtaacagcct atattccagc tcgtaaaaga ggagaaggaa ttaattttta tggcttgtca
     8521 accagtctag cagcagctat tggccctttt gtaggaacct ttatgttgga taatcttcat
     8581 attgattttc gcatggttat tgtcttatgt agcgtcttga ttgggtgtgt ggttgttggt
     8641 gcttttgctt ttccagtcaa aaacatgtct ttaaatgcgg agcaattggc taaaaccaaa
     8701 tcgtggactg tggatagttt cattgagaaa aaagccttgt ttatcactgc aatcgccttt
     8761 ttaatgggga ttgcctatgc ttcagtttta ggatttcaaa aattatacac gtctgaaatt
     8821 catttgacaa cagtaggcgc ttatttcttt gtggtctatg ccttaatcat taccatcact
     8881 cgtccagcaa tgggacgttt aatggatgct aaaggcgata aatgggtctt gtacccaagt
     8941 tatctttttt tagtaatggg actcttcttg ctaggtagtg tatcgtctgg aggaagctat
     9001 ttgctttcag gagccttgat tggctttggt tatggcactt ttatgtcttg tggtcaagcc
     9061 gcctccatac aaggagtgga tgagcaccgc tttaatacgg ctatgtctac ttatatgatt
     9121 ggtcttgatt taggtttagg tgctgggcct tacctcttgg gcttgattaa agatttggca
     9181 cttggtagtg gtgtggcttc ctttaggcac ttattctggt tagctgctgt gattccactg
     9241 atttgtacct tgctttactt attaaaaaca aagacaagac aggttttgtc ttaaggacaa
     9301 gaaaaggagt ttagtcttat acttaaatac aaacgtatct taacagctgt agatagttcc
     9361 tatgagccgg gattagctgt gggtaaagcc attactatag cgctttaaaa taattctagt
     9421 ttgctattcg tacatgtcaa taaaaatgac tcgcaaaagc cattcgtgaa agagaaaatg
     9481 tggccttatt tttagtaggt acaattggat taagcacgtt tagatacatg acaattggat
     9541 taacatcaga atataggctt tgtcatgtta agattgatct gttgatagtg agagctaata
     9601 aaaaatgtta taatactatg aaataaagtg ataaagataa ggccttttat ggtccttttc
     9661 tttaccgctt ttattattgt gtgaaaataa cacttaatga tcattttatt tattatttta
     9721 ttacctttac attcatcaat aagcctgtta aaatggtatt tgttatattt tattatttgg
     9781 aggaaaccag aaaacatgga aatgacatgg actgtgaaat acatcacaga atttatcgca
     9841 acggcttttt tgattatttt gggaaatgga gctgttgcta acgtcgactt aaaaggaaca
     9901 aaaggacata actcaggttg gttagtgatt gcttttggct atggcttagg agttatgatg
     9961 ccagctttga tgtttggtaa tgtatctgga aaccatatta atcctgcttt cacagttgga
    10021 ctagcagtat caggcttgtt cccatgggct cacgtcttac aatacgttgt ggcacaatta
    10081 cttggagcta tctttggtca gttggtagtg gtaatggttt ataaacctta ctttatgaaa
    10141 actgaaaatc caaatcatgt tttaggctca ttctcaacga tttcatctct tgataatggt
    10201 caaaaagaca gtcataaagc ctcttatatc aatggtttct taaacgaatt tgtaggttca
    10261 tttgttcttt tctttggtgc tttggctttg actaaaaact actttggggt agagttagtt
    10321 ggtaaattga ttgaagcagg ctacgaccaa acaactgcag caacacaaat ttcaccatac
    10381 gtgacaggct cattggcggt tgctcacatt ggtattggtt tcttagttat ggtcttggtt
    10441 acttcattag gtggaccaac tgggccagca ctaaacccag cgcgtgattt tgggcctcgt
    10501 ttgttacacc acttcttacc aaaatcagtt cttggtcaag ccaaaggtga ttcaaaatgg
    10561 tggtatgcat gggttcctgt agttgcacct atcttagcgg cgatagtagc cgtagcagcg
    10621 tttaaatacc tttatatcag ataaaaaaag aactaaagct tcttttagac tcaagacaag
    10681 ctcgcttaag gaacttgtct tttttatatg agttaagcga aatctaatgc aaacttgact
    10741 gtcttgtata gcgtattttg taaattttat tagacttctt gtaaaaagcc tctcctcaga
    10801 taagatgact aatgcctcta aacggtgtta caaataaacg aggcatccct aacttccttt
    10861 atctggtgtt gaaactattt tgcacggact aaatcactga cagagtaaaa aacgattttt
    10921 catttttgtt gtaaaatatt aaaaacgtct ctggttagtg attcccagaa acgttatctt
    10981 atctatttgt ttgttgctta tgagaggtaa aggaggaacg aatcagcatt ccaccagtga
    11041 agaaaacgat agcgatgacc agaagtttca agctattaat atctaaattt gttaagaaaa
    11101 acacagctag taaaacgcca ataataccac cagaaacaat tccagcaaaa ccatcccaac
    11161 tgacacggtt tgctttgata aactggctac tagaagctgt cataatcata gctgcatcta
    11221 gcatcataac aggcatagca actgttgggc taagacccat taatgaaaag aaaatcaatt
    11281 ctggagcata attgcctaac cccatagtca tcaagactcc aacgataaaa ttaaaaccaa
    11341 ttccaacaaa aagccagatg ccatggaggc catgaatggt gtctgaaagg tgttctcctg
    11401 gatggtagat tattctaatg atcatgatta tagctgctat gattaaaaga ctaccaagga
    11461 ttcgttggac agttggagca tgccagtttt ttgtaatatg agtcccaaaa taagctccaa
    11521 taaaggctgc tgcagccata gcaagtaaag ttagaacctc aacttttacg acaaaaataa
    11581 agcaaagaga ttgaatgagc accggaagca catgagctac ggtcatagtg ccaggcaatt
    11641 gtctatcgtc agtgactaat ttagttaact taaagcacgt tgtggtagta gcaaaagacc
    11701 ctatcccaag ggtgtcaagg gcatctgtta gcaggccaat ccaaaacccc gtccaaaagc
    11761 gtttaaaagg attgatctta ttttttttaa gatgttttac taacataaag aaaataaaaa
    11821 gcattgccga aactagcaaa gcttgtatca gtctaaggat aagcatttcg ttcataaaga
    11881 ctagtttaca aaaaaaaacc ttagccgtca acgtgattta cttcattaaa acatgccact
    11941 atgcttagaa gagctttagt tcgatgtatt ttgttaaaat taagctaaaa tattaatatt
    12001 gcatgaaagg ggacgccttc ctttttccct tactgagctt agctgttatt gtagtgaatg
    12061 tttaaaaggc tagtttgtcg ctctttatca aaaatctagt aggatgaata cgtataattt
    12121 cttgtcaaat agaggaattt tgtctataat agcagaggat taggaggaaa ttatgacttt
    12181 aatggaaaat attaccttta aaactccagt attacgcgtt aatgatcgcg accttaatat
    12241 tgcattttat caaaataatt tagggcttcg tttagtatct gaagaaaatg cgattgctat
    12301 cttttcatct tggggagaag ggcaggaatg ttttgtaatt gaagagtcac cttcagttag
    12361 aacgcgtgcg gtagaaggcc ctaaaaaggt taatacgatt gtcatcaaaa caaatcaacc
    12421 taaagaaatc gaacaattat tagctcatgg agcacattat gacgctcttt ttaaaggtca
    12481 aaatggctat gcctttgaga ctatttcccc agaaggagac cgattcttgt tgcatgctga
    12541 acaagatatt aaacatctcc aaggtactga tttaccatcg cttgaaaaag atgcgacttt
    12601 taaaggttta actcaattta agtttgatat tattgtttta aatgttatta gtgaagaacg
    12661 ctcaaaagct ttttatcggg atctgtttag tgatcagtta cctattacta tggattttat
    12721 tcaagaagaa ggtcccgatt tggcaattga tccccatatt gcttgggatt tagaaatttt
    12781 agaatttcaa gtctcaaagg actatgatat gaaggtccta aaagcaactt tagaagaaga
    12841 cgggcacaag gtctacattg ataaaaaaca caaagtattg gtcctttctg atccaagtca
    12901 gatcgaagta tggtttacga aatgactttg gcagtcatta aatgtattga aaaccatctt
    12961 cacaaaaaag tatacaaagg ggccagtctg gctctctttc aatctggtcg atggcaagaa
    13021 taccatatcg gaacaattga tggaagacga ccagttgatg ctaacttagt ttatgacttg
    13081 gctagtgttt caaaagttgt tggtgtggcc acaatatgca atattttatt gaataatggt
    13141 acgttagcat tagatgatcc cttaaaagta tattatccta gtattgctga tacgactgtc
    13201 actattcgac agttattgac tcataccagt ggtcttgatc cttatattcc taacagagat
    13261 gttttaaatg cacaacaatt aagaaaagca cttaatcatc ttactcaaaa agaaaataaa
    13321 aacttttatt acacagatgt taatttcctc ttgttaggct ttatgttaga agagctcttt
    13381 agtgaatctt tagaccagat atttgataag actatcttta ctccctttgg gatgtatcat
    13441 acgtcttttg gccctcgtcc agaagctgta ccaacattaa agggtgtgag tgatggagaa
    13501 gttcatgatc ccaaagcaaa aatcttaaaa aaacattctg gatctgcggg gctattttca
    13561 actcttgcag atttagaaag ttttagcgat cattatctta atgatccatt ttcagattgt
    13621 ctgtggcgca actacagcca acaaacaatt gagcggtcac tagggtggaa tttagatggc
    13681 gattggatta gtcatacagg ttacacaggg ccgtttctaa tgcttaataa aaaagagcaa
    13741 acggcagcta tttttttgac caaccgtact tacgacgagg atgataaaag taaatggtta
    13801 aaagaacgtc agttgcttca caatgcacta aagcatgatc tgacaacacc cgtatcgtaa
    13861 cgtctaaagg ggcagtttta gtgatcttat tactgttttt aaagtttctt ctaaaaaata
    13921 gccatttcat ttgtctgatg cgattagagt gattataagt gaaaaaagaa cagccatctc
    13981 attttgaatc aaatgagatg gctgttcttt tttataagtt attgatcatt tagatactac
    14041 tatttatttg aaatagcttc agcggcatca tccattgaaa gcacttcgtg gaagacacgt
    14101 tgagtcaatt cagttttttg ttctggtgta aggtatttgg tgttgacaca gtaaccagag
    14161 atacgtacga taacgtcttc gccgttcatg attttgtcat aaacatcgtt aaggtccata
    14221 acgttcaagt taacgtgctg accaccattt tcaaagtaac cgtcaagcac tgttaccaag
    14281 ttgtcaactt gttcgtcaaa tgttttacca agagcacgag gtgatacttg agtagtcaat
    14341 gagataccat cgttagcatg tgagaattcc agtttagcaa gtgagttaag gttttgtaac
    14401 cagccacctt ttgctttgtt agatgggtta gcacctggtg agaagaattc cacttggcta
    14461 gtgttaactg taccatcttc gttcaagaag acgccgcggt gaactggaga gttaccagtt
    14521 tgtttagagt aagcaacgtt tgaagtgatg gtaagaagtg atactgaagc ctcagcattc
    14581 ttgtaaagtt tgtggcttgc aagacgtgtg tggtaagctt ccatcaacca tttcgcgatg
    14641 tcatcaacac ggtcgtcatc ttcaccgtaa cgagggaagt cacctgttac ttcgtagtca
    14701 tagatgtagc cattttcatc gcggatagtt ttaacagttg cgtatttaat agctgacaag
    14761 gtatcaactg tgttagcgaa accacagata ccgaatccca tgttagcacg ttggtgtgtt
    14821 ggcaagaagg ccatttgaac tgcttcgtag ttgtatttat cagtcatgta gtggatgatg
    14881 ttaagcgcat ctacataagt atctgtcaac cagtcaagag atttctcaaa gttagccata
    14941 acttcgtcgt actcaaggac ttctgatgtg attggttcaa caacgttaaa cactttgtag
    15001 tctctgtgaa catcatcgta accaccgtta agaccagtaa gaagggcttt aagaacgttt
    15061 acacgagcac cgaagtattg gatgttatga cgttgttctt cattttctgg gtcaagtggt
    15121 gatacacaac atgaaataca tgacatttca ccataacctt ctttagccat tgttgtcaca
    15181 ccttcatatt ggatagaaga gtgtttgtgg ctcattttca tacagtagcg acggaatgtt
    15241 tctggcagtt ggtcagtcca aagaactgtt aagtttggtt ctggagagtt accgatatta
    15301 tcaagagtgt ttaagaaacg gtagtccatc ttagtcacac ggtgacgacc gtcgttaccc
    15361 ataccagcca tagaagttgt gatgaatgtt gggtcacctg agtaaagggc atcgtaagct
    15421 ttagtacgac caaattttac ggtacggagt ttaaggacaa aatcatcaac aaattcttgg
    15481 atttctgatt ctgtaaaggt accgcgagca aggtcacgtt ctgcaaagat atcaagaacg
    15541 attggcacac gtccaagaga agtagcagca ccgttgatca cacgacatac agccatgaaa
    15601 gcgatgttta cccattggat agcttcttta acgttttgtg ctgggcgacg aacatcaact
    15661 ccgtaaaggt caccaagttt aaccacttca ccaagagctt ggtattgaag gttaacttct
    15721 tcgcgaagac gaatggattc ttcatcgatt tcagtgatag cattccagtc attgactttt
    15781 tcttgcatca agtagtcagc accgtaaaga gcaagacgag cgtaaacacc gatgatacgt
    15841 ccacgtgagt aagcatctgg aagaccagtt acagtgtggg catgacgagc gcgacgaata
    15901 tttgaagtat aagcgcggaa gataccgtcg ttaacagttg tcacatactt agtaaagatt
    15961 tcatgtactg ctgggtctgg ttcatagccg ttttctttaa gggtcgtttc cgccatacgg
    16021 ataccacctt ttggcatgaa gttcaatttg aacaattcat cgttttgaat accataaatt
    16081 aattcatttt ctttatcgat gaaaccagca ggaatgtcag caattgaagt tggacgagta
    16141 tcgtatggga aacgtgtagc ttcatagtgt gcttttgttt cttcgataac ttttttgatg
    16201 tgaagtgaac gttcagtagc accagccaag aaagattcat cgccatcgta tggggtgtag
    16261 ttagcttgta caaaacgtga gacacttgct ttttctttcc agtcagttcc tttaaagcct
    16321 tcccaagctt tttcgaaaac atctgtattg gttttaacag ttgccataaa tttctcctta
    16381 aattctagta acaaagcgat ctgttacatt tacaattcta agtttaacac ataggaaacg
    16441 ttttcccaag caaaattctt gacaaaatta agattctttt ataatacaga ttgttgaaac
    16501 agtcacaaac tgtattagaa tgtatttttt tggctttaga tagcctaaaa ggtataatag
    16561 agaaaggagg gacttatgct tatttttcca ctgattaatg acacgtcacg aaaaatcatc
    16621 catattgaca tggatgcctt ttttgctgca gttgaggaaa gggataaccc tgctttaaaa
    16681 ggaaagcctg ttgtgattgg gaaagatcca agagaaacag gtggtcgcgg agttgtttcc
    16741 acttgtaatt acgaagcgag aaaatatggc attcattcgg ccatgagctc taaggaagct
    16801 tatgagcgtt gtcccaaagc catttttatt tcaggaaatt atgaaaagta tcgaacagtt
    16861 ggagaccaga tccgccgtat ttttaagcgt tatactgatg tggttgaacc tatgtctatt
    16921 gacgaggctt accttgatgt gactgataat aagttgggga ttaagtcagc tgtgaaaatc
    16981 gctaaactga ttcagcatga tatctggaaa gaagtaggat tgacctgttc agcaggtgtg
    17041 tcttataaca aatttttggc taaattggct agtgattttg aaaaacctca tggcctcacc
    17101 ctagtcttga aagaagatgc cctgtgcttt ttagccaaac tccccattga aaagtttcat
    17161 ggtgttggta aaaaatcagt tgaaaaactg catgacatgg ggatttatac aggacaggat
    17221 ttgttggcag ttcctgaaat gaccttgatt gatcattttg gtcggtttgg ttttgacctt
    17281 taccgtaaag cgagaggcat cagcaattct cctgtcaagt ctgatcggat acgcaagtca
    17341 attggcagtg agagaaccta cgctaaactg ctttatcaag aaacagacat caaggcagag
    17401 atcagtaaaa atgctaagcg cgtggccgct ctcttacaag accataaaaa gttaggcaag
    17461 accattgtgc tcaaagtgcg ttatgctgat tttaccacct tgacaaaacg tgtcaccttg
    17521 ccagaattaa ccagaaatgc cgcacaaatt gagcaagtag ctggggatat ttttgacagc
    17581 ttaagcgaaa atcctgctgg tatccgcctg ttaggggtaa ccatgaccaa tttggaggat
    17641 aaggtagctg atatttcctt ggacctatag gagaaagagt gctctatccg tccgcctcat
    17701 tttggagaaa aaagaagctg attagggatt tccctaatca gcttctttgg tccattattt
    17761 tattacagca tagcttggtc tgtatcatca cctttttcgt taagggtttt agccttgtaa
    17821 aaagcaaagc cataaagagc agcttgtata aggataagga tagttccaac cattgacatg
    17881 gttgttgtga actggttaac caagccgata acagaaagga taaggcctaa gatataagga
    17941 atataactaa ccgttagacc ttgttttaat ttagataagt tttgagcaca aaagacaatg
    18001 atagcaataa tagcaaagac atttaagaca gataagaaaa tcataaatgg tgtcatgctg
    18061 ctttgtagct gtgccaattg ctcagttgtt aattgggccc gaaatgcttc attcttgagt
    18121 tggctttgta agtagaaaat ccctgcaaat cccattaatg acagtacaac tccaagcccg
    18181 tttagaataa taatggcaat agtagacgtt ttgagtgcct gacgcacttt ttcataagaa
    18241 atcatataat cctcctagag tccttaatcc gaaattgtac aatgtgttta atacaaaaat
    18301 attataccat agattaatca aaaatgtccg tttttctagg attttttctg gaaaaagagg
    18361 gcaatatctg actctgtaag ccctatcatc gaatcgatag tcgaataatt ctcaggtgtt
    18421 aacctaaaat catcattatc tgactgagag ttctcagtgg ggttagcgtt tgttgattga
    18481 gaggaagatt tttgagagtc gtcctcaagg gttgccgtat tagaaaaaag ggaggtttgc
    18541 tcttttgatt ttagctcttg gttaggttga gaggaggcta agtcggattg ttcttggaag
    18601 cgttcgatca agtaggtttg gcgtttatcg ccttcgtgtt taatagcata ctcaaaggca
    18661 gtatattctc ccaacagaat taacttactt ttagaccgag taatggccgt gtaaatcaca
    18721 tttcgttgca agagtcggcc gctttggcgt gtgataggta aaatcaccac ttgaaactca
    18781 ctcccttgcg atttatgaat gctcatggca taggccaggg ttaattttag ccattcattt
    18841 ctagggtacg tgacttcgct accgtcaaaa tctaagatta attcgtcttg cttagattcg
    18901 gtgtatttag caggaatcaa atctgtaata taaccaatat ctccgttaaa gacattcaac
    18961 tgagcatcgt tgactaagtg caggacttta tcacctttac gaaaatacgt atcattgaac
    19021 agaaattctg tttgtccttg caagggattg agaagttctt gcatgagttg attaagatga
    19081 ttgatgccag cttgtccttt gtacataggc gctaaaattt gaatttcctc agcagggatg
    19141 ccacttttaa tagcagatag gacaattttt tgaatcatgt cagggataaa ggctgcttgg
    19201 gcttcaaaat aagaacggtc agctttttta tcacgaaagt cagcagctaa gattcctcga
    19261 cgcatctgat ctgccaaatt gacaatagta gattcttggg attgacgaaa tatcttttgc
    19321 aaggcgattt ggggcaggct attgactttt aaaagatctg acaggacttg accgggtcca
    19381 accgaaggaa gctggtcact atctccgaca ataatcactt gagttgttga gttaatagct
    19441 cctaacaact ggttggcaag ccaggtatcc accattgaaa attcatcgac aatcagcaag
    19501 tcgcagtcta gataatcctc catggcttgg taatcgttgt cgccattgag gcctaagtgc
    19561 ctgtggatgg ttgcgctagg aagtccagtc aactcattca tgcgacgtgc agctcgacct
    19621 gttggagctg ctaacaagat aggaaggtct tttttatcca aatcaatctg atgcaggttc
    19681 gcgtaagcct gcaaaatgcc tcgaataaca gttgtttttc ctgttccggg accacctgtt
    19741 aggagaaaga ccttgctggt taaggcctta gtaatggctt cttgctgcac ttggtcatag
    19801 gtgatggcaa agtctttttg aacggcttgg atggttgttt gaatggtatc atgactaaat
    19861 gactgactta aaggggtatc taagagacga gagatgttgt tagcaatccc ttcttcagca
    19921 aaataaaggc tagcatcaaa cagtttggtg tcactgtttt tgattttgcc ctctatgatt
    19981 aactcgctta gttgttcagc cacagcagca ggatcacatt ctacttgacg tgcatcttca
    20041 aggagtgtaa tggcaaagtc taataattgt cgtgcttgga cataagtatc tcctcgattg
    20101 atggattctt ccaagagaca gtgaaggagg gctgcacgaa aacgtttcgg agagtcgctt
    20161 tcaatcccta agttttcagc gagagcatct gccattttaa acccaaaacc ttgtagatct
    20221 tcgactaact gatagggatt ttctttaaca aggtcaagag cctcttcttt atacttttca
    20281 aacgcttgaa aggcaaaacg gttgctaagg ccaagttcga cgagaccagc aatcagttgc
    20341 tctgtgccgt aattcaattt tagtttagcg acaaaggctt gacgattagc cttagatagg
    20401 ccagagatag tttctaattt acttgggtct tctaaaatat ggtcaatggt attatgacca
    20461 tatagtgcaa tgattttctc cgctgttttt ttaccaatcc ccttaaaatg gtcactagag
    20521 aaataattaa ccaaaccaga tgaactaggt ttgatttttt ggtaacggtt tagcttgagt
    20581 tgttgaccgt atttagggtg ctgggtcaat tctccccaaa aggtgtagtc atctccttca
    20641 ataatgtcag ccatcgttcc tgtgataatg atttcaaagt cgtcaatgtc actgtctgta
    20701 tcctcaatgg caaggaggag aattttaaag aaattagcct ggttttcaaa aatgatacga
    20761 tcaacagtac ctgtaaaaac gtattccata gtaactcttt ctatttatac aagataactg
    20821 aaaacctgcc caaaggcagg ttttttctaa ttaaagacgg tcattttatt gagtggccaa
    20881 aaacgagctt tcacttcacc gataaggttt tcttttttga aactaccaac ttcgcgacta
    20941 tcccgggaaa caatacgatc atcaccaaga agaaggtatt ctccttttgg aacactcatc
    21001 tcaaagcgtg tttgtccctc agaattagtt gtaaaagcat cagatgtttc tgctaactgt
    21061 tggaataggg tattataggc gtaagttttt tggagtttat cgtttttaaa ttgttttaga
    21121 tactcagcca aatacggctc aactgttttt ttaccattaa tataaagtgt gtcatcatta
    21181 taagaaatgg tatcgcctgg caatccaata actcttttta cgatttcttt cttttgtccg
    21241 ttttcttctt cctgagcaac tacaatatca aagcgatcaa tcctagcttg attaaaaacg
    21301 ataaggcgtt cgccatgagc tagagttggg tccatagaat ggccgtctac tttaacagcc
    21361 tgccacaaaa aaagacgaga tagaccaaag agaattaaaa agagagtgaa tgggccccat
    21421 tctttaataa actgtttcat atgattcctt ttatttagtg agaagcgctt gcgctttgtg
    21481 agtgttggcg aagtgaagtt tagcactata ttctaagcta gacataccat aagcggctaa
    21541 gagttggcta gcaactttat ctgaagctga accagcaccg cttgggagtt ggtaacctaa
    21601 atcttgacct aattgatcga gattgtctaa aaatagattt ctagcaatga tagagctaac
    21661 agccacagcc aaatagtgac tttctgcctt ttcttgaaag gttagaggat ttgggaaatg
    21721 gtttttttcc ttttttagat gcttttcata atttgattgg ctagtgaaag catcaataac
    21781 aatttgttta ggttgaatgc ctttttgtaa caacaaaaaa atagcttggt tatgaagagc
    21841 aactttgata gaaatggcat tatatggttt acttttacca accaattcgt tatatttttt
    21901 aggtgatagg agaagtgatt gatgaggtat ttgtttctct aacagaggcg caatctgttg
    21961 aatggtttta tccgataatt ttttagaatc atcaacccca agctttttca ggaaggaatg
    22021 atctttagga tcgacaaaac ttgccacaac agcaatccca ccaaaataag agccattacc
    22081 cacctcatca ctgccgatta taggtatatc ttggctattg ttgcttgctt caaaaactgt
    22141 cttagctact ggaagattaa gctcttgagc taaagcattt gcaccgtttc cctggagaac
    22201 taattttccg gatttgtaca gcaaaacagt aaccccattt tttttagcag caaaggctac
    22261 ataggtattt tggctactga tggtgtagga ggctagctgt ttttttaaat gtttactcag
    22321 tatagcatct attttcaaaa ctaaggtatt cataataatt attttaacat aaaatagttg
    22381 actatggtta attcataagt ttatttaaca aagaaaacag agactcgaat gtttagacgg
    22441 gttagggcaa tggtgttgac tattttacga aagtttcatt ttacggtata atgctaatga
    22501 ggtgacccta tgaaaagtat taatcgctat aaattcacct ttggtgaaaa aacattaaca
    22561 ttgacaactg acaaagacaa tctctttatg gaagaagttg agcgggtagc taaagaaaag
    22621 tatcaggctc ttaaaaatca tttaccagaa gctgatgacg agacaatcgc tattttaatg
    22681 gctatcaata ccttgtcaac acaattaagc agagagattg ccattgaaaa aatggaagct
    22741 gaaattttag atttacgtca aaaaaccttg gttggtcttc aagaaaaagc taatcaaata
    22801 gatgtgaatg aggtttaatc atgttatctt tattgatagt gcttatttta acttggaatt
    22861 tttatattgg ttatagtaga ggtattattc ttcaatcgtt ttatgtctta ggagccctac
    22921 tttctctttt ggtagctaat cgattttata ttggattagc ccataagcta acgctttgga
    22981 ttccttattc taacccggta gaaggaacat cagtcttttt ctttaaatca gttgatatct
    23041 ttgttttaga taaggtttat tatgcaggcc ttgccttttt tatcattttc ttattggggt
    23101 atgcattgag tcgctttctt gggatttttg ttcatttcct tttgctagat tattttgata
    23161 accagtggac aaaatgtttg agtggcggac tagcgcttct agtatcgctt ctttttttga
    23221 acatgttact gtctattttt gcaacggtcc ctatgccttt tttacagcac tatttgcact
    23281 ctagttttct tgctcgtttg gtgatcgaac accttccacc attgacaata attattcaaa
    23341 aattgtggat tcaagccatt atttgatatc gttttgtgac taatataaga acctggagtg
    23401 agtttcacct ttaggttctt tatttacgag aaactgttta gaaataaaga gaacgcatgg
    23461 gaacttagtg actttcttgc cccattttcc atcattttag gtataatgaa gagtatgaat
    23521 aacaagattt tagagcagtt agaatttaac aaagttaagg aattgctatt accttatctc
    23581 aagacagaac aatcacaaga agaattatta gagctggagc cgatgacgga ggctcctaaa
    23641 atagaaaaaa gttttaatga aatttctgac atggaacaga tttttgttga acatcactca
    23701 tttggcatag tcagcctaag ttcaatctct gagagtttaa aacgcttaga gctttcagct
    23761 gatcttaata ttcaagaact tttggctatc aaaaaagttt tacagagttc ttcggagatg
    23821 attcactttt attctgattt ggataatgtt tctttccaat ctttggatcg tttgtttgaa
    23881 aatttggaac aattccctaa tctgcaaggg tcttttcaag ctatcaatga tggtggtttt
    23941 ttagaacatt ttgcgagtcc agaattagag cgtatccgtc gtcaattaac aaatagtgaa
    24001 cgacgggttc gtcagatttt acaggatatg cttaaggaaa aagcagagct tttatcagaa
    24061 aatctaatcg ctagtcgtag tggacgaagt gtcctaccag taaaaaatac ttatcggaat
    24121 cgtatttctg gtgtggttca tgacatctct tcttcaggaa gtactgttta tattgagcct
    24181 cgtgctgtag ttacactaaa cgaagagata acgcagctta gagctgacga acgccacgaa
    24241 gaaggtcgta ttttacacgc attttcagac ttgttaagac ctcatgtcgc cactattaga
    24301 aataatgcat ggattcttgg gcatcttgat tttgtaaggg ctaaatatct ttttatgtct
    24361 gataataagg cgacgatacc taagatttct aatgacagca cgttagcatt aatcaatgtt
    24421 cgtcatcctc tgttaagtaa tcctgtggct aatgacttac attttgatca cgatttaact
    24481 gcaattgtca tcactggtcc caatactggt ggtaagacga ttatgctaaa aacactcggt
    24541 ttagcacaat taatgggaca gtctggtttg ccagtattag cggataaagg tagtaaaatt
    24601 gcagtattta acaatatctt tgcagatatt ggcgatgagc aatctattga acaaagtcta
    24661 tcaacttttt ctagtcatat gacgcacata gtcagtattt taaacgaggc tgaccacaat
    24721 agtttagttc tctttgatga actgggagca ggaacggatc ctcaagaagg tgctagtttg
    24781 gctatggcta ttttagaaca ccttaggtta agtcatatca aaacgatggc gaccacgcac
    24841 tatccagaat taaaagctta tgggattgaa acaaattttg tagagaatgc gagcatggaa
    24901 tttgatgcag aaacgcttag tcctacgtat cgctttatgc aaggagttcc tggacgctca
    24961 aatgcatttg aaattgcttc tcgccttggt ttagctccat ttattgttaa acaagctaag
    25021 cagatgacag attctgactc agatgttaac cgtattattg aacagttaga ggcacagaca
    25081 cttgagacac gtagaagact ggatcatatt aaagaagttg aacaagaaaa tctcaaattc
    25141 aatcgtgcgg ttaagaaact ctataatgaa ttttcacatg aacgcgataa agagttagaa
    25201 aaaatctatc aagaagctca agaaattgta gatatggctt tgaatgagag tgatactatc
    25261 ttaaaaaaac tcaatgataa gagccaatta aaacctcacg aaattataga tgctaaggca
    25321 caaataaaaa aattagcacc tcaagttgat ttatcaaaaa ataaagtctt aaataaggct
    25381 aaaaaaatca aagcagctcg tgcccctaga attggtgatg atattatagt gactagttat
    25441 ggacagcgag gtaccttaac tagtcaatta aaagatggcc gttgggaagc acaagtggga
    25501 attatcaaaa tgacattaac acaagatgaa tttagcctcg ttagagtcca agaagaacag
    25561 aaagtcaaaa ataaacagat taatgtggtt aaaaaggcgg atagttctgg accaagagct
    25621 cgacttgatc ttagaggtaa aagatacgaa gaagctatgc aagagttaga tcattttatt
    25681 gatcaagcat tgcttaacaa tatgggacaa gttgatatca ttcatggtat tggtacaggc
    25741 gttattcgtg agggagtgac aaaatatctt cgtcgtaata agcatgttaa gcattttgct
    25801 tatgccccac aaaatgcagg gggatctggt gccacaattg taacgttagg gtaaatgatg
    25861 gaatcatatg aacactttta tgccaaacta tctcaacctt ttagaaaaac cccacagtta
    25921 ataattcttt taaatgtttt actaaaaata atcacaggag tgatgtacat actttatcca
    25981 tcttttctga tatttacgct ttggcaaggg atgacatttc aattatggtt aaggttatta
    26041 attattcctg ctgttggctt tatagctttg tcttacatta ggaaacgctt tgattttcca
    26101 cgaccgtatg aaaaatggaa tattaaacct ttaattgata aggatacaaa gggaaggtca
    26161 atgcctagca gacatgtttt ttcagctacg atgattagta tgtgtttgtt acgatattat
    26221 gtttactttg gaatagtttg tttaatatta tcggctttat tggcaatttg ccgtgtgata
    26281 gcaggtattc actatcctaa ggatgttatt gtaggttacc ttattggctt gatgttaggg
    26341 ctttgtttat tgatttagcg agttcgtagc aaatagtttc aaaaacaact aaattcttgt
    26401 acaataggct tatcattaag atgaaatgga gaaaaaagat ggcattagaa gtaacagatg
    26461 ctacatttgt agaagaaact gaagaaggtt tagtactcat tgatttttgg gcaacttggt
    26521 gtggtccatg tcgtatgcaa gcaccaatct tagaacagtt atctcaagaa atcgatgaag
    26581 atgaactcaa aattttgaaa atggatgttg atgaaaatcc ggaaactgct cgtcagtttg
    26641 gtattatgtc aattccaaca ttgatgttta aaaaagacgg agaagtggtt aaacaagttg
    26701 caggtgttca tactaaagac caactgaaag ctattattgc tgaattgagt taactaaaat
    26761 aaagcccagc gtcacgctga gctttatttt atgacctact aacttcaatg gaataaccat
    26821 gtaaacataa aacgacttgc aaaagcaaaa gcaacagtaa tgaggaaaaa tacagtgaca
    26881 ataaggggtt tctgataagg aagttttgct ctttcttctc gtttttcgat ttcgtctaat
    26941 aattttccat ttgaaacagc taggatttcc ttataaggtt gcacatcata ttttttctta
    27001 aaacgttcca cacgattagc ataagtcata gtaattatcg ataataaaac aaaaatgcca
    27061 agtcctagcc actctaagaa atagacttaa tggataactt gaaatcatta atagtatcat
    27121 caatgttacc attactttgg tatctcgttt aaaattcttt ttatcaacct gagtgatggt
    27181 atatttcatt ttctcaatgt ctcctttaat gagttggtct gagctcactt gaaaaatttg
    27241 acttaggagt aagaggctat ggatgtctgg gtaagttttg tcattttccc agttagatat
    27301 gctctgacgg cttacataga ctttctcggc taatttttct tgcgagagcg cttgttgttt
    27361 acggtagcga ataatttgct gaccaatttc cataaatatc accgaaaaac tttacagcgg
    27421 cgtaaaggaa ttgtaaacaa aaagtgaacc gttatagttc acttgcgatt aagcattttt
    27481 ctgttttaag taggtctcta gcattttctt ttgcggtgtt gcaaagggat acagagaaaa
    27541 gtcctcaatt gctacccact ttaggtgagg agcattaggt aaatctgttg ctttgaccac
    27601 cccctctatg agttctattg tccacttctg gtgactaaaa gtgtgcttaa tatttggaaa
    27661 gtgattatca gtccattgtg gctttaattg atattctctt tcgaaagttt cattttgggt
    27721 ttgccagatt atggggttgg attgattgtc atcaaataaa tctaattgtt gagaaagagg
    27781 tgacgtttcg ataataggaa atgaccaaaa acctcctaga agtctccctt tagtattttt
    27841 ctccagtaga tattggccat cttggttacg aatgacaaaa gcctgaattc gcattggtct
    27901 aggctttttc tttggatttt ttatggggta tttaccataa gtaccattca aataagcagc
    27961 gttaaagaaa cgaatagggc tttcatcagg cctaggtgtc ttagcggatt cgatgtctgt
    28021 acctagatcc ataagtgcct ggttaaaatc accgggtctg tcagggtcaa ttagtatttc
    28081 cataatagct tgaaaaattt tacgattttt agggtcaccg atatcataat taacttcaaa
    28141 caaacgagcc atgacacgca tcacattgcc atcaacagca ggctctggta agttgaatga
    28201 gatgctggcg atagcacctg cagtataagg accaatccct tttaatgaag caatatcatc
    28261 ataagtgtga ggaaatatgc caccaaaatc aaccatcact tgctgtgcag ccttttgcat
    28321 attacgcacc cgagaataat agcctagtcc ctcccatgcc tttagtaatt gttcttcagg
    28381 agcgtctgcc aaatctttta tttgaggaaa ccactctaga aaacgtttat aataagggat
    28441 taccgtatta acttgtgttt gttgcaacat gatttcagaa acccaaatat agtatggatt
    28501 agtagttctt cgccaaggga gatcacgttt ttcttggtca taccacccta aaagtgtgcg
    28561 acgaaaagaa gcgattgtct cattatccca catattaata ccataatctt ttaattcaat
    28621 catgttgtta ttgtaacaca ggagtcttaa aaagagtaaa aaaagatttt aggtatttgc
    28681 gaaaaagaaa aggaaatatt ataataatat taggtttacc tcatctaaat gttgatttag
    28741 aataactgaa attaacgata gaagcagata ggttttaatt tggaggggac atgttccaga
    28801 aattaaagaa tcttattgat cggtattcgt ggttcgtttt tataatgatg attcttgtgt
    28861 tatttcttaa ctatatttat ccatttgatc cttctttgag cggactacag ttggaatggc
    28921 tgatcatgac gcaagttttt cctggattag gtatcgtatg tgccatggtt gctattattt
    28981 ttaaaaagtt taaccttttt gttttggccc taattttata ttttgcactt tggttaaaac
    29041 ttttccttgc tttttctttt ttcacctatt ttttaggagt ctgactaagt gccaattttt
    29101 aaaactcgtg aaagaaaatg tttgacaaaa cttagtcaag tagaaaaagt tccttgcttt
    29161 taattgacta ttagtgtaca ataagattct gtgagtatac ctcacttact cactccaaaa
    29221 gtagtgagtc attagaccaa aaggaggaaa atatcaatgg ctaaatacga aattctttat
    29281 atcattcgtc caaacattga agaagaagct aaaaacgctt tggtagcacg ctttgactct
    29341 atcttgactg acaacggtgc aactgttgtt gaatcaaaag attgggaaaa acgtcgtctt
    29401 gcatacgaaa tcaacgattt ccgtgaagga ctttaccaca tcgttaacct tgaagcgact
    29461 gacgcagcag ctcttaacga gtttgaccgt ctttcaaaaa tcaatggtga cattcttcgt
    29521 cacatgatcg ttaaacttga cgcttaattc caactaagag ggtagtttat gattaataat
    29581 gtagtactag ttggtcgtat gaccaaggat gcagaacttc gttacacacc aagtcaagta
    29641 gctgtggcta ccttcacact tgctgttaac cgtaccttta aaagccaaaa tggtgaacgc
    29701 gaggcagatt tcattaactg tgtgatctgg cgccaaccgg ctgaaaattt agcgaactgg
    29761 gctaaaaaag gtgccttgat cggagttacg ggtcgtattc agacacgtaa ctacgaaaac
    29821 caacaaggac aacgtgtcta tgtaacagaa gttgttgcag ataatttcca aatgttggaa
    29881 agtcgtgcta cacgtgaagg tggctcaact ggctcattta atggtggttt taacaataac
    29941 acttcatcat caaacagtta ctcagcgcct gcacaacaaa cgcctaactt tggaagagat
    30001 gatagcccat ttgggaattc aaacccgatg gatatctcag atgacgatct tccattctag
    30061 tcagaatgga ttgaacgaat acgaaattat ttgagttcgg gctaaaaatt tagaacttag
    30121 aatttagatc aactccctag gaaatcaaga tttcttgcca gttttctaaa attcagtcgt
    30181 tttttaagag cccttaacat cataatttat aaaggagaaa atacatggct caacaacgtc
    30241 gtggcggatt caaacgccgt aaaaaagttg acttcatcgc agctaacaaa attgaatatg
    30301 tcgattacaa agatactgag cttcttagcc gtttcgtttc agaacgtgga aaaattcttc
    30361 ctcgtcgtgt aacaggaact tcagctaaaa accaacgtaa agtaacaaca gcaatcaaac
    30421 gtgctcgcgt tatggctctt atgccttacg taaacgaaga ctaataaaca aacagtccat
    30481 ttcggactgt tttttagttg actaggacta gtctaggcgt ctaggtgagt tttttctaaa
    30541 agagagaatg atagtaaacg aaaatccttg cgtagacagc aaggatgaaa tgattgttat
    30601 ttgttaacag gtgacatagt gttttgaatg ttgtatttgc gttgtaggta atagcgtaaa
    30661 gcaagggaaa caccaccaat aatgagcaag gcaagaggag gcaactgtgg gttaagagag
    30721 gttggtaaaa aggcagtcgc agagtacaag gcaatccaaa tcaacatggc taatgataag
    30781 gctgcgatga ttttgaacca acttggacga aggctcttat cttttccgag atgacggtaa
    30841 ataaagtaat aagtagcgta catggatgct cctccaccaa aaccaagtgc cagtaaggaa
    30901 atcaatcctg taactgtagc gtttgtgttg aagaaggtca tgatgccatt taaaagggca
    30961 acaattccga tgaatagtaa agaggtatct agccacatca accaaggatt ggtgtttttg
    31021 tcagtttctg ctgctctttg actagggtct tggctaaaag aagctgccca agcagtcgga
    31081 gtgcctaata gatttcgagc ggtgacacct tttttctggt tttctagaat agctggaata
    31141 gcttcttcga gaatcagctt aatgtcctca tcagacttgc cgtcttggat taatttgttc
    31201 gtagcggtgt ggataaattc ttgatttttt ttggtaagtt cttgtaattc catgggaatc
    31261 ccttctttat atgggttagt taaagtaagt caatggtatt agctagtgtc aaatgagact
    31321 ttggagccag tcgtttgaca cagagttttg tcaggtgtta accgcattct gcagcttgct
    31381 ccactctaga accatttttt tctaataaag taaatcacaa caaaggaact aaggagcata
    31441 gcaatcaagg taatatacca aaaagcatgt tctaggccat ttagtggtaa ccagttgttt
    31501 tggaaattca taccataggc ggagaaaatc acagttggta tatctaaagc catggtcatc
    31561 aaggccagtg ttttcataat agtgttctgg ttgttgttga taatagaagc agtggtttca
    31621 gtcatggcat tcaagacatt ttcataaatg ccagccatct caatggcctg ttgggtttca
    31681 atcaaggtat cttctagcaa atcctcgtcc tcaatgtatt tcttgagaga gcttgttgag
    31741 ctggataatt tcttgacgat gcgttcgttg aatttcaagg aagcctttaa gtagacaatg
    31801 gatttttcaa gttccatcat gtcgataagt tcttcatttc gagtagctgc ttcaagctga
    31861 gcttccaaac gttcgctttg gcgatcaatg gtcctcaagg cagtcagaaa gagctcggcg
    31921 ttgcgatata gaatctgaaa aacaaaacgt gtcttcatga aggtatagaa atttttgacc
    31981 cggcggttgt gaaaatgatc gaaaagggtc atgtcatgca gacaagttgt gataacagca
    32041 ttttccgtta caataatgcc taaaggcata gtaatatagt aacttttatt gttacgttct
    32101 tcgtatatcg ggacgtctac gataattagg gtataatcat cttctacggc aatacgtgag
    32161 gtttcttcca cgtccaaagg ggcgcgcaag tcagaaatat caatgttaaa ttgatcggcg
    32221 atcttcatag actcttcttg ggaagggtta accagtttaa tccaagctcc tggctcgaat
    32281 gtttctattt ctttgaattc aattgccgat gaaagaaaca tttgtttcat gacaagccct
    32341 cctttttgat gattgactgg tagagattga catcaaacct tgataataaa gccttctcaa
    32401 ggattttctg aaaaattctc aatacttatc tattatacca aaattcgcaa agtttggggc
    32461 aataggttat cagaaatttt tgttataata taagaaagct cgatgaggag ggtgccttta
    32521 ggcacattca agatgcaaaa taaaataata attcatgggg caagagccca caatttaaaa
    32581 aatattgacg tggaaattcc acgagacaaa ttagttgttg tgacagggtt atcagggtca
    32641 ggaaaatcta gtctagcctt tgatactatt tatgcggaag ggcaacgtcg ttacgtagaa
    32701 agtttatcag cttatgctag acagttcttg ggtaatatgg aaaaaccaga tgtggattcc
    32761 attgacggtc ttagccctgc tatttccatt gatcaaaaaa ctaccagtaa gaatccccgc
    32821 tcaacggttg gtacggtgac tgaaatcaat gattatttac gtttactata tgcgcgtgtg
    32881 ggcacacctt actgtattaa tgggcatggg gccattacag catcttctgc agaacaaatt
    32941 gtagagcagg tcttagccct ccctgaacgg acacgcatgc agattttagc gcctattgtt
    33001 cgccggaaaa aaggtcaaca caaaaccatt tttgagaaaa ttcaaaaaga tggttatgtc
    33061 cgtgtgcggg ttgacgggga tatttttgac gtgacagaag tgccggagct gtcaaaaagt
    33121 aagatgcaca acatcgaggt ggttattgat cgtctggtta ataaggatgg tattcgtagc
    33181 cgtttatttg attcggttga agcagcttta aggctgggag atggctacct tatgattgac
    33241 actatggatg gcaatgaact gctcttttct gagcattatt cctgtcctgt ctgtggattt
    33301 acggttcctg aattagaacc aagactcttc tcttttaatg cgccgttcgg ctcttgtccg
    33361 acctgtgatg ggctaggcat taagttggaa gtggatttgg acttggttgt tcctgaccca
    33421 agtaagtctt tgagagaggg agctttggcg ccttggaatc ctatttcctc caattattac
    33481 ccaaccatgc ttgagcaagc tatggcaagt tttggggtgg atatggatac accttttgag
    33541 gccttgactg aggaagaaag agatttagtg ctttatggtt caggtgatag agaatttcat
    33601 tttcactatg tgaatgattt tggtggtgag cgtaacattg acattccttt tgaaggtgtt
    33661 gtaactaatg ttaatcgccg ttatcacgaa actaatagtg attatacgcg caatgtgatg
    33721 cgtggttata tgaacgaatt gacctgtgcg acttgtcatg gttaccgttt gaatgaccaa
    33781 gccttgtgtg tgcatgtggg tggcgaagaa ggacctcata ttggtcaaat ttcagaatta
    33841 tcgattgccg accacttgca gttgttggaa gaactggaac tcacagaaaa tgaaagtacc
    33901 attgctaaac cgattgtcaa agaaattcat gaccgcctga ccttcttaaa taatgtggga
    33961 ctgaattatc tgaccttgtc acgggctgct gggactttat caggtgggga aagtcaacga
    34021 atcaggttag cgacacaaat tggttctaac ttatcagggg tgctctatat cttggatgag
    34081 ccttctattg gattgcacca aagagacaat gaccgtttga tcgaaagcct gaaaaaaatg
    34141 cgtgatttgg gtaatacctt aattgtggta gaacacgatg aagataccat gatgcaggca
    34201 gactggctga ttgatgtggg gcctggggca ggtgagttcg gtggagaaat tattgcctct
    34261 ggaacgccga aacaagtggc taagaataaa aaatccatca cgggtcaata tttgtctggt
    34321 aaaaaattca ttccagtgcc attagagcgt cgttctggta atgggcgatt cattgaaata
    34381 aaaggagcag cgcagaataa tcttcaaagc ctcgacgtga gattcccact gggtaaattt
    34441 attgcggtca caggggtatc aggctcaggg aaatcaacct tggttaatag tattttgaaa
    34501 aaggctgtcg cccaaaaatt aaaccgtaat gctgataagc ctggtaaata tcactctatt
    34561 tctggtattg aacatattga acgcttgatt gacattgacc aaagtccgat tggaaggacg
    34621 ccacggtcaa atccagccac ctatacgggt gtctttgatg atattcgaga cttgtttgcc
    34681 caaaccaacg aagctaagat tcgtggttac aaaaaaggcc gtttctcttt taatgtcaaa
    34741 ggtgggcgtt gtgaggcttg ttcaggtgat gggattatca aaatcgaaat gcactttttg
    34801 ccagatgttt atgtgccttg tgaggtttgc cacggcagac ggtataattc tgagacgctt
    34861 gaggtgcatt ataaagaaaa aaatattgct gaagtgcttg acatgactgt cgatgatgcc
    34921 ttggtatttt tctctgctat ccctaaaatt gcccgaaaaa ttcaaaccat taaggatgtt
    34981 ggtttgggtt atgtgacctt gggtcaacca gctactactc tatctggagg agaagcgcag
    35041 cggatgaaat tagctagtga attgcacaaa cgctcgatag gtaagagctt gtatatccta
    35101 gatgagccaa cgactggttt acacacagat gatattgcaa ggctattaaa agttttggaa
    35161 cgctttgtag acgatggtaa tacggttctt gtgattgagc ataatttgga cgttatcaaa
    35221 tctgctgacc atattattga cttaggacca gaaggtggtg tcggaggtgg tcagattgtt
    35281 gccacgggga caccagaaga ggtagctcaa gttaaagaaa gctatactgg tcattatttg
    35341 aaagtaaaac tacaacaata ggattaggag ttcgtttgag ctccttttaa tcttttaaat
    35401 gctctcaaat catggtaaac ttaaagtagt tttttcatgc tacaatattc tcaaaagtta
    35461 ccaaaggagt ttgcgatgtc aggattttta gagcaacgat taggtcactg cctaaggcag
    35521 atggcagaga aggggctaga ggctcttctg gtcacccatt taaccaatag ttattacttg
    35581 acaggttttt ctggaactgc agcaactgtt ttgataacgg ccaaacgtcg tgttttgatc
    35641 acagattcac gttatacctt gcttgctaaa gctagtgttg agggatttga tattatcgaa
    35701 agccgcacgc cgcttaaggt tgtggcagaa ttgttagagg ctgatcaaat agattgcctt
    35761 ggttttgagg accaggtatc gttttctttt tatcaggcca tgcaagcaga actgtcagga
    35821 ataaccttgc ttgctcagtc aggttttgtg gagcatttac gtcttattaa ggacgcctct
    35881 gaaatcgaga ccattgctaa agcgtgctcg atctcagaca aagcatttga agatgctctt
    35941 gattttatta aaccagggac aaccactgaa cgtgacctgg ctaatttttt agattttcgc
    36001 atgcgtcagt atggtgctac cggaacgtca tttgatatca ttgcagcttc aggctatcgc
    36061 tctgccatgc ctcatggacg cgccagtgac aaggttatcc agaataaaga gagcttgacc
    36121 atggactttg ggtgttacta caatcactat gttagtgata tgacgaggac cattcatatt
    36181 ggccaagtta ctgatgaaga acgtgagatt tatgctcttg ttcttgctgc taataaggct
    36241 ttaattgcta aagctagcgc tggcatgact tatagtgact ttgacggtat tccgcgccaa
    36301 ctcatcactg aggcgggtta tggtagtcac ttcacacatg gcattggtca tggtatcggg
    36361 cttgacatcc atgagaatcc attttttggg aaatctgagc aacttctcca agctggaatg
    36421 gtggtcacag atgagccagg tatctatctg gataacaaat atggcgtccg tattgaagat
    36481 gacttggtca tcacagaaac tggttgtcaa gtcttgacct tggcccccaa agaattaatt
    36541 gtattgtaaa agaatggttc aggaaaggat taggggagaa gcaatgacaa atcgtttatc
    36601 atggcaagac tattttatgg ccaatgcaga gctgatttcc aagcgctcta cctgtgatcg
    36661 cgcctttgtg ggagctgttt tggtaaagga taaccgcatt attgccacag gttacaatgg
    36721 cggagtttct gctacggata actgcaacga agcgggtcat tatatggaag acggacattg
    36781 tattcgcact gttcatgctg aaatgaatgc tttgattcaa tgtgcgaaag aaggaatttc
    36841 aacggacgga actgaaattt acgtgactca ttttccttgt attaactgca ctaaggcgct
    36901 tttgcaggcg gggattacaa agattaccta taaagcacat taccgtccgc acccctttgc
    36961 cattgaactg atggagaaaa aaggggttgc ctatgtgcaa catgatgtgc ctcaaattgt
    37021 tttaggaggc gataaggaac aatagaaagt gtacctaaaa ggacggtcat aaaagatttg
    37081 agccaaggcc acttttgtgg taaaatgaag tgataaatat tttagtaaga ggtaataata
    37141 atgattgaag caagtaagct taaagcaggt atgacatttg aagcagaagg aaaattaatc
    37201 cgtgtccttg aagctagcca ccacaaacca ggtaaaggaa acactatcat gcgtatgaaa
    37261 ctacgtgatg tgcgtacagg ttctactttt gacacaactt accgcccaga tgaaaaattt
    37321 gagcaagcca tcattgaaac tgtcccagca caatacctat acaaaatgga tgacactgct
    37381 tacttcatga acactgacac ttatgatcag tacgaaattc cagttgctaa cgttgagcaa
    37441 gaattgcttt acattcttga aaactcagac gtgaaaatcc aattttatgg aagtgaagtg
    37501 attggggtaa cggttccaac aactgttgaa ttgaccgttg cggaaacaca accatctatt
    37561 aaaggagcga cagtgacggg ttcagggaaa cctgcaactc ttgagacagg acttgttgtt
    37621 aacgttccag actttatcga agctggccaa aaactaatca ttaacactgc agaaggtact
    37681 tacgtttctc gtgcttaatc ctttgtcaaa acagattagt ctaaaaaaga gaaaggaaat
    37741 gctatgacaa ctgaatatat cggtgaaatc gtcatttcac cacgagtgct tgaggttatt
    37801 acggggattg ctacgacaca agttgagggc gtccactcac tccataacaa gaaaatggca
    37861 gatagcttta acaaagcaag tcttggtaaa ggggtttatc tccagacaga agaagatgga
    37921 agtgttacag cagatattta tgtttacttg caatatggag ttaaggtccc gactgtatct
    37981 atgaatattc aaaaaacagt caaatctgct gtgtacgata tggcagaagt gcctatttct
    38041 gcagttaata tccatgttga aggtattgtt gcggaaaaga caccaaaacc agatttgaag
    38101 tcactttttg atgaggattt cttggatgac taacagcttt caaaattcaa gaagagattt
    38161 gcgtgaacgt gcctttcagg ctttatttaa catagagatg ggagctgagt tattggcagc
    38221 ttctcagttt gcctatggtt atgataaagt aacaggggag gacgctcaag tattggagct
    38281 gccgattttt ttattaagtc ttgtgacggg tgtcaataat cataaagaag agttggataa
    38341 cttgatatca actcatttga aaaaaggttg gtcgttagaa cgcttgacac taacagacaa
    38401 aacgttatta cgactaggtc tttttgaaat caagtatttt gacgaaacac cagaccgtgt
    38461 tgcactaaac gaaatcattg aagtagctaa aaaatattct gatgaaacct ctgctaaatt
    38521 tattaatggc ttacttagcc aatatgtctc ggaagctcct tcagcaaata aatcataata
    38581 agtcggagca atcttaggat tgtatccgat tttttcaatt tatgtacgaa tattaaaaga
    38641 caaacaagca tactctcgca tctagaaaga gtatgcttgt ttgtctttta gagtaattag
    38701 tgattggtta tgttttgttt aaatacttgc tcctggaagt agcgtaatcg gtaaaatata
    38761 gtctttactg gttttttctt ttttaatttt tttgatgagt atttcgacac tcaatttagc
    38821 aatctcatca ataggttgac gaatggtcgc taattgagga acatattgct ggataaatgt
    38881 cgttccatca taacctatga ctttcatatc ctctggaata gtaatgtgaa gttgtttggc
    38941 tactttcata ataaggatag cagttaaatc atcagaaacg aaaaggccat caggttttcg
    39001 ggttgccaaa atggatttaa tttccatttc gcgtctaaca ggagataggt tatttggtaa
    39061 tttgaggatt tctgcacttc gtttgagctg gtagttaaac cctagctggc gcaaccctgt
    39121 gggcgaatca gaattgtcat tacctgtaat catgacaatg ttttgacaac cgtgtttttg
    39181 caaagtttgt gcggctaatt taccaccttc aaaattatct gaagaaataa ccgggatatt
    39241 tggcgccaga ttacggtcaa aagctacaat aggagcttcg acacgctcat aatcctcaat
    39301 tcccaaatta tgactggaag aaataatgcc gtccacttga ttggccgcaa gcatttctaa
    39361 gtattcgcgt tctttgacgg gattatgttc actattgcaa ataatagttt tgtagccctg
    39421 tttaaacaat tcaatttcca aatgttcaat taattcagcg taaaagatat tgctaatgtt
    39481 ggggaagata agcccaatga gttgggttga tttaccttgc aaacttctag cgagattgtt
    39541 aggcttgtag cccaattcac gcatggcctt attcacctta ttcactgttt tttgggaaag
    39601 gtagcctttt ttgttgatta ctcgcgaaac agttgttgga ctgacacccg ccaaggctgc
    39661 cacgtctgtt aattttgcga ccacttgcct aatacctcat ttcataataa tgtccaaaag
    39721 cttgtccttc tactacttgg atacctgttt gtccttgggt tgggaaaaca cgactcgtta
    39781 ggactttttg cccttggtta ataaagattt caagaatgga attgtccaca tagacattaa
    39841 gtgtaacatg gccttgtggg atttggcaag agcgcaccgt accatagtct tgggcatatt
    39901 gaacccctgc ccgacttcgg tcaatgctta actgtccttt tgttgtatcc actttcaatc
    39961 ttaggccatt ccctttttgg tcggcaaata ggagcaggtc aagctttttt tggcctggaa
    40021 tcgtcaattc caattcataa cagttagaac tgtctatttt attatgaaat aattctgctg
    40081 gccctcgaag attttgtagg gctgaaacag gtgtttgata gagaattccg tctttaatcc
    40141 ttaattcttt cactaaacta agagctcctt gatagttata acgatctgtc ggataatcaa
    40201 tatctggtaa cccaatccaa gacacggcta gaaccctgcc atctggacta ctaaaggctt
    40261 gagtggcata agcttcaaaa ccaaagtcaa gattttgaag ggccccccca cccagcaatt
    40321 ggccagtttc tggattgaag ctttcaaaaa ttttataggt attggggtag atattttgat
    40381 aatctaaatc agctttagcc agtccttgtg ggctgaaaat caaaacaggc ttgtcatcga
    40441 caaacacaag gttggggcat tcaatcatgt attccgtacc agaatcgtca aagtccaaat
    40501 cggctataaa tcgccagttg tccacatgat tgtccacagc tttgtaaagt ttgatttttc
    40561 ctttgccatc taaaccttgg gcgccaataa tagcatagaa ttgaccttga taagaaaaaa
    40621 gctgaggatc ccgaaaatgt tctgtaacat catcgggctg ttcaatcaaa acctgtggta
    40681 ttttggaaat atttccttgt ttatccatcc atgcgccaac ctgtaatggt gttctgaccc
    40741 aattggcatc gcgaacatta ccagtgtaaa agaggaagag cttgtcatca atagcatagg
    40801 cagaacctga gtaagcccca tgactatcgt gagcgtggtc tggcagaagg cggctccttg
    40861 tttccgtaaa atggacgagg tctgtggatg tcatgtgtac ccattgtttc agaccatgcg
    40921 cagccccata aggccagttt tgataaaaaa gatggtagcg accgttgaaa taagaaaacc
    40981 cattggggtc attgagtaat cctgtcttag gttcgacatg aaattggctg tgccatgggg
    41041 attgggccat tttttcagta atagcttggt agtcttttga gctccactct ttgtaagggc
    41101 ggtagcgaat agcttgtggt agatccatca aaatctcctt gttttatagt cgtcttcaag
    41161 aatatactaa acgttttctg tttaaaaatc aagaatttaa agcatataaa ataaaaatat
    41221 gttaaacgct tgacataaaa aatattagtg ataaaatgat agtcaagaag tgaagcggat
    41281 tcactagcgt tggtcctgca cattcttagc cacaaagctg gcagaatgga ggagggacta
    41341 acaccaaatg aaaaaggaga cttttaggca tggataatcg tcagattgca gctgaagtga
    41401 ttgaggcttt aggtggtcga gaaaatgtga gaagtgttgc ccactgtgca actcgccttc
    41461 gcgtgatggt ttatgatgaa ggaaagattg ataaggaaaa agcagaagct attgacaagg
    41521 ttaaaggagc tttctttaat tctggtcaat atcaaatgat ttttggaact ggtaccgtca
    41581 ataacattta tgacgaagtc gttgctcttg gtttaccaac atcatcaacc agtgagcaaa
    41641 aagcagaagc aggcaaacaa ggcaatatct tccaacgggc gattcgtacg tttggagatg
    41701 tctttgttcc cattattcca gctattgtag caacgggtct ctttatgggg gttcgtggtt
    41761 tggtgaccca gccagctatt atggatttat ttggggtgca tgagtacggg gaaaattttc
    41821 tcatgtacac tcgtattcta acggatacag cctttgtcta cttgccagct ttggtggctt
    41881 ggtcagcctt tagggtcttt gggggtaatc ctattatcgg tattgtttta ggcttgatgt
    41941 tggtgtccaa tgaattgcca aacgcctggg tagttgcctc tggtggagat gttaagccgc
    42001 taaccttctt tggatttgtt cctgttgttg gttatcaagg taccgtttta cctgccttct
    42061 ttgttggtct ggtaggagct aagctggaga aatggttgca caaaaaggtt ccagaagctt
    42121 tggacttatt ggtcacaccg tttttaacgt ttgctattat gagtatcttg ggactatttg
    42181 tgattggacc agtcttccat tctcttgaaa accttgttct ggctgggaca caggccgtct
    42241 tgcatttgcc gtttggtatt gcaggcttga ttgttggggg aatccaacaa ttaatcgtag
    42301 tgactggtat tcaccatatc tttaacttcc tagaagcgca gctaattgcc aataccggaa
    42361 aagatccttt caatgcttac ctaacagcag caacagctgc tcaagctgga gctaccttag
    42421 ctgttgctgt taaaaccaaa tcaacaaaac taaaaggtct ggcctttcca tcaaccttgt
    42481 cagctctttt agggattact gaaccagcta tttttggggt caacctccgt tatccaaaag
    42541 tctttgtttc aggtcttatt ggtggtgcct taggtggttg ggtcgctagg ctctttggca
    42601 ttgcaggaac tggttttggg attacagtct taccaggaac tctcctttac ttgaatggcc
    42661 aattattaca ataccttgtg actatgcttg tcggtcttgg ggtagccttt gcaattgctt
    42721 atacttgggg ttatcaagat agagaaaccc ttccgttacc agctgtcgaa gttgatcaaa
    42781 cggctgatca gccagcctta gcagaggaaa ctttatatag tcctttgaat ggaacagttg
    42841 tagatttagc agctgtttca gaccctgttt tttcatcagg tgctatgggt caaggcttag
    42901 caattaagcc agaagataat accctatact caccagttga tggtaaagtt gaaattgtct
    42961 ttgaaacagg tcatgcctat gctataacgt caagtcaagg agcagaagtg ttacttcata
    43021 ttggtattga taccgtgtcg atggcaggag atggctttga atctcttgta gcagtaggtc
    43081 aggcggttaa aaaaggtgat cttcttggac actttgatcc tagcaagatt gcagaagctg
    43141 gactagatga catcaccatg atgattgtga ccaatagcgc tgactatcaa agcgtggaca
    43201 ttcttgctca aggacatgtt ttgattggtg atcaagtggc acttatcaaa taaggacaaa
    43261 agagctaact aagcagctct tttgtcctgc catgaatggc aggttggcaa aaaaatgaga
    43321 aaagcctaaa aaccttaaat ttgtgttatt ttacctatac tttgtacctt gtttttttta
    43381 ataaagtgtt gttatactta aggcgaacta taggaatgcg cttacataga tggtatatca
    43441 actgggaagc catgacttag taccaaaaat aaggagtgtc caaatggata aacatttgtt
    43501 ggtaaaaaga acactagggt gtgtttgtgc tgcaacgttg atgggagctg ccttagcgac
    43561 ccaccatgat tcactcaata ctgtaaaagc ggaggagaag actgttcagg ttcagaaaga
    43621 attatcttct atcgatagct tgcattatct gtcagagaat agcaaaaaag aatttaaaga
    43681 ggagctttca aaagaaaaag taccagaaaa ggtcaaagag atattagcaa aagctcagca
    43741 ggcagataaa caagctcaag aacttaccaa aatgaaaatt cctgagaaaa taccgatgaa
    43801 accgttacat ggtcctctct acggtggtta ctttagaact tggcatgaca aaacatcaga
    43861 tccaacagaa aaagacaaag ttaactcgat gggagagctt cctaaagaag tagatctagc
    43921 ctttattttc cacgattgga caaaagatta tagccttttt tggaaagaat tgggcaccaa
    43981 acatgtgcca aagttaaaca agcaagggac acgtgtcatt cgtaccattc catggcgttt
    44041 cctagctggg ggtgataaca gtggtattgc agaagatacc agtaaatacc caaatacacc
    44101 agagggaaat aaagctttag ccaaagctat tgttgatgaa tatgtttata agtacaacct
    44161 tgatggctta gatgtggatg ttgaacatga tagtattcca aaagtaaatg gagaagctag
    44221 tgacgaaaat ctcaagcgat ctattgatgt ttttgaagaa attgggaaat taattggacc
    44281 aaaaggtgtt gataaatcgc gtctgtttat tatggatagc acctacatgg ctgataaaaa
    44341 cccattgatt gagcgaggag ctccttatat tgatttgtta ttggtacaag tctatggcgc
    44401 aagaggagaa caaggtgagt ttcaaaacga taccaagtta gttaccgaga ctcctgaaga
    44461 acgatggcaa ggttatagca agtatattcg tcctgaacaa tacatgattg gtttttcttt
    44521 ctatgaggaa agagcaggca gcggcaatct ttggtatgat attaattctc gcaaggacga
    44581 ggacacggca aatggaatta acactgacat aactggaacg cgtgccgaac ggtatgcaag
    44641 gtggcaacct aagacaggtg ggattaaggg aggtatcttc tcctacgcta ttgaccgtga
    44701 tggtgtagct catcaaccca aacaaatagc tgaaaaagat aaacagaatg taaaaaataa
    44761 tcagcctcag attccagaga ttactgataa cattttccac tcagattata gtgtctccaa
    44821 ggcattaaag acagttatgc taaaagataa gtcgtatgat ctgattgatg agaaagattt
    44881 cccagataag gctttgcgag aagctgtgat ggcgcaggtt ggaaccagaa aaggtgattt
    44941 ggaacgtttc aatggcacat tacgattgga taatccagcg attcaaagtt tagaaggtct
    45001 aaataaattt aaaaaattag ctcaattaga cttgattggc ttatctcgca ttacaaaact
    45061 cgaccgttct gttttacccg ctaatatgaa gccaggcaaa gataccttgg aaacagttct
    45121 tgaaacctat aaaaaagata acaaagaaga acctgctact atcccaccag tatctttgaa
    45181 ggtttctggt ttaactggtc tgaaagaatt agatttgtca ggttttgacc gtgaaacctt
    45241 ggctggtctt gatgccgcta ctctaacgtc tttagaaaaa gttgatattt ctggcaacaa
    45301 acttgatttg gctccaggaa cagaaaatcg acaaattttt gatactatgc tatcaactgt
    45361 cagcaatcat gttggaagca atgaacaaac agtgaaattt gacaagcaaa aaccaactgg
    45421 gcattaccca gatacctatg ggaaaactag tctgcgctta ccagtggcag agggaaacat
    45481 tgatttgcaa agccagcttt tgtttgggac tgtgacgaat caaggaaccc taatcaatag
    45541 cgaagcagac tataaggctt accaaaatca taaaattgct ggacgtagct ttgttgattc
    45601 aaactatcat tacaataact ttaaagtttc ttatgagaac tataccgtta aagtaactga
    45661 ttccacattg ggaaccacta ctgacaaaac gctagcaact gataaagaag agacctataa
    45721 ggttgacttc tttagcccag cagataagac aaaagctgtt catactgcta aagtgattgt
    45781 tggtgacgaa aaaaccatga tggttaattt ggcagaaggc gcaacagtta ttggaggaag
    45841 tgctgatcct gtaaatgcaa gaaaggtatt tgatgggcaa ctgggcagtg agactgataa
    45901 tatctcttta ggatgggatt ctaagcaaag tattatattt aaattgaaag aagatggatt
    45961 aataaagcat tggcgtttct tcaatgattc agcccgaaat cctgagacaa ccaataaacc
    46021 tattcaggaa gcaagtctac aaatttttaa tatcaaagat tataatctag ataatttgtt
    46081 ggaaaatccc aataaatttg atgatgaaaa atattggatt actgtagata cttacagtgc
    46141 acaaggagag agagctactg cattcagtaa tacattaaat aatattacta gtaaatattg
    46201 gcgagttgtc tttgatacta aaggagatag atatagttcg ccagtagttc ctgaactcca
    46261 aattttaggt tatccgttac ctaacgccga cactatcatg aaaacagtaa ctactgctaa
    46321 agagttgtct caacaaaaag ataagttttc tcaaaagatg cttgatgagt taaaaataaa
    46381 agagatggct ttagaaactt ctttgaacag taagattttt gatgtaactg ctattaatgc
    46441 taatgctgga gttttgaaag attgtattga gaaaaggcag ctgctaaaaa aataaacaaa
    46501 gcaactttct tagatagcaa cattcagatt aaattaacaa aatgtgacta tgataaaggt
    46561 ttgctggaat tgattaacca aaagactcaa aatctgagat gaatagtccc agattttgag
    46621 tcttttatag gttttgatga cataaagcta aataatcgtt agactaccag aaagtggcgc
    46681 ttgtccgtga gacatggctg tcttgataag agcctgtgtc atcataaaga taaaaaagaa
    46741 caagaaaaag gagaaaacat gggaaaatta tatggaagca ttgaagctgg tgggacaaag
    46801 tttgtctgtg ccgtgggtga tgaggagttt acagtggtgg ataaaacaca atttctgacc
    46861 accacaccag aagaaaccat cgcgcgaacc atcgcttatt ttaaagcttt tgaggcagat
    46921 ttggctggta ttgctattgg ttcttttgga ccaattgata ttgatccgtc gtcagagact
    46981 tacggttaca tcacaaccac tcctaagtca ggctgggcta atgtggattt gttaggacaa
    47041 ctttcggctg cttttaagat tccttttgat gtgacaacag atgttaatag ctctgcttat
    47101 ggtgaggtgc ttgctcgtcc tggtgtggaa agtttggtct attacaccat aggtactggt
    47161 attggggcgg gagctattca acatggccac tttattgggg gattaggtca tacagaagcg
    47221 ggtcatacct atgtcatgct ccatcctgat gatatggcca agggattttt aggtgtttgc
    47281 ccttttcata aagggtgtct ggaagggatg tcagcaggtc caagtattga ggccagaacg
    47341 ggagtgagag gtgaacgact tgatcaggaa gctgatgttt gggacattca agccttctac
    47401 attgcccaag cagcgctgca agcaactatg ctttaccgtc ctcaagtgat tgtttttggc
    47461 ggaggtgtca tggcgcaaga acatatggtg ttgcgcgtgc atgataaatt cactaccctt
    47521 ttaagcggtt atttgccagt ccctgatttg acagactaca ttgttactcc agctgttgct
    47581 gataatggct ccgctactct gggaaatttt gctttggcca agttggctgc acaaggaaaa
    47641 tagggtctgt ttttgcctgc ttgtctagta aaagaaagcg cagtcagcta gaacatgcta
    47701 taataaacag agattaacat cagaagcgag gaatattatg tcagaaccat tatttctaaa
    47761 atcaaccatg cacgacagaa tttggggtgg caccaagttg agagatgtct ttgcttacaa
    47821 catcccaagt gacaccacag gtgagtattg ggctatttct gctcatccta atggtgtttc
    47881 gacagttact aatggacgtt atcaaggaca acctttaaat acattatatg cgcaagagcc
    47941 agccttgttt gggaatccaa aggaagaagt ttttccactg ttaactaaga ttttagatgc
    48001 taatgactgg ctaagtgtcc aagttcatcc tgatgatgct tatggacgtg aacatgaagg
    48061 agaattaggc aagacagaat gctggtatat tatttctgcc gaagagggtt ctgaaattgt
    48121 atacggccat caggccaagt ccaaagaaga ccttcgtgcc atgattgaag caggcgcttg
    48181 ggatgatttg ctgactcgtg tcccagtcaa agcaggcgat tttttctatg ttccaagtgg
    48241 caccatgcat gcgatcggca agggaattct tattttagaa acccagcagt catctgatac
    48301 cacttatcgg gtttatgatt ttgaccgtaa ggacgttaat ggtaatcttc gtgaccttca
    48361 tattgaaaag tctattgatg tcttaacgat tggtaagcca gaaaatagcg tgccagccac
    48421 tatggttttg gataatatgg tagcaacaac tttagtctca acgccatttt tcactgttta
    48481 caaatgggta actagtcaaa tggttgacat gaaacaagct gcgccttatc ttttagtgag
    48541 tgttttaaaa ggtcaaggaa aactctatgt ggaccagaag gcttatgagc tagaaaaagg
    48601 catgcacttt atcttgccta acgatgttaa atcgtggtca tttgatggtc aattagaaat
    48661 gattgtgagt caccccaatc aactcgttta ataccatggt atcaatatga gaaaaaagga
    48721 taaaattatg actctctgtt tctctgataa ctttaccaac ctttcttgaa ctgcctgcat
    48781 atttatgtta aaatgaaatg attagatgat cgaaaggaaa gagaatggcc aatattctac
    48841 gcaaagttat cgaaaatgac aaaggcgaac taagaaaatt agaaaaaatt gcaaaaaaag
    48901 tagaatccta cgcagaccaa atggcgtcat tgtcggatag agatctacaa ggaaaaacac
    48961 ttgaatttaa agaacgctat caaaaaggtg agaccctcga acaactatta cctgaagctt
    49021 tcgcagttgt tcgtgaagca gcaaaacgtg tgttgggctt gttcccttat cgtgttcaaa
    49081 ttatgggagg aattgttctt cataacgggg atgtccctga aatgcgtact ggtgaaggaa
    49141 aaactcttac agccaccatg ccagtttatc tcaatgctat tgctggtgag ggtgttcacg
    49201 ttattactgt taatgagtat ctttcaacgc gtgacgctac cgaaatgggt gaagtgtata
    49261 gctggttagg tctttcagtt gggatcaacc tagctgctaa gtctcctgct gaaaaacgtg
    49321 aagcttataa ttgtgatatt acttattcaa ccaactctga agtcggtttt gattaccttc
    49381 gtgacaacat ggttgttcgc caggaagaca tggtacaacg cccactcaat tttgccttgg
    49441 ttgatgaagt ggactcagtc ttaattgacg aggcaaggac acctttaatt gtttctggtg
    49501 ctgttagctc tgaaaccaat caattgtata ttcgtgctga catgtttgta aaaactctga
    49561 cgtcagtgga ttatgttatt gatgtgccca ctaaaacgat tggattaagc gattcaggta
    49621 ttgataaagc tgagagttat tttaacttga gcaatcttta cgatattgaa aatgtagcct
    49681 tgactcactt tatagacaac gcccttcgtg caaactatat tatgttgtta gatatcgatt
    49741 atgtggtcag cgaagatggt gagattctta ttgttgacca atttacaggt cgtacgatgg
    49801 aagggcgtcg cttctcagac ggcttgcacc aagctattga ggcaaaagaa ggcgttcgta
    49861 ttcaggaaga atcaaaaacc agcgcctcaa tcacctacca aaatatgttt cgtatgtaca
    49921 aaaaattggc aggtatgact ggtactgcga agaccgagga agaagaattt cgcgaagttt
    49981 ataacatgcg tattattcca attccaacca atcgtccaat tgcccgtatt gatcacactg
    50041 atttgcttta cccgacctta gaatcgaagt ttagagcagt tgtggaagac gttaaaacgc
    50101 gtcatgcaaa aggacaacct atccttgtag gtacggttgc tgttgaaact agtgatttga
    50161 tttcacgcaa gctggttgaa gcagggattc ctcatgaggt tttgaatgct aaaaatcact
    50221 ttaaagaagc tcaaatcatt atgaatgctg gacaacgtgg tgctgttaca atcgcaacta
    50281 acatggctgg tcgtggtact gatatcaagc ttggtgaagg tgttcgtgaa cttggtgggt
    50341 tatgtgtcat tggtacagag cgtcatgaaa gccgtcgtat cgataaccag cttcgtggac
    50401 gttcaggtcg tcaaggagat ccaggtgaat cccaattcta tctttcatta gaagatgatt
    50461 tgatgagacg tttcggctct gatcgtataa aagccttttt ggatcggatg aaattagatg
    50521 aagaagacac tgttattaaa tcaggtatgt tagggcgtca agtggaatct gctcaaaaac
    50581 gggttgaagg aaataactac gatacccgta aacaggtctt acaatatgat gatgtgatgc
    50641 gtgaacagcg tgaaattatc tatgctaacc gtcgtgatgt cataactgct aatcgagatc
    50701 ttggcccaga aattaaagct atgatcaagc gtactatcga ccgtgctgta gatgctcatg
    50761 cacgtagcaa tcgtaaagat gctatagatg ctattgtaac ttttgctagg acctcgctgg
    50821 taccagaaga gtctattagt gctaaagagt tacgtggttt aaaagatgat caaatcaaag
    50881 agaagcttta tcaaagagcg cttgctatct acgaccagca actatcaaaa cttcgtgatc
    50941 aagaagctat tattgaattc caaaaagtac tcattttgat gattgtggat aacaaatgga
    51001 ctgaacacat tgatgcctta gatcaacttc gtaatgctgt tggacttcgg gggtatgctc
    51061 aaaataaccc tgtggtggaa taccaagcag aaggtttcaa gatgttccaa gatatgattg
    51121 gtgctatcga gtttgatgta acacgtacca tgatgaaagc acaaattcac gaacaagaac
    51181 gtgaacgtgc aagtcaacgt gccacaacag cagcacctca aaacatccaa tcgcagcagt
    51241 cagctaacac cgatgattta cccaaagtgg agcgtaacga agcttgtcca tgtggttcag
    51301 gcaaaaaatt caaaaattgt cacggtcgta aatccttctc ataagaacga gacacaacag
    51361 gacaaagtta ggtatataga aagaagctga gaataattct cagcttctca ctgtttaaat
    51421 cttctaacat taagatgaaa taaggtttgg tggaaagtaa tgattgttgg acatggaata
    51481 gacttacaag agatttcagc tattgaaaaa gtttatcaaa gaaatcctcg ctttgctcaa
    51541 aaaattttaa ctgagcagga attggctatt tttgagagtt ttccttacaa acgtcgactc
    51601 agctatttgg caggacgctg gtcaggtaag gaagcttttg ctaaggctat agggacaggt
    51661 attgggcggc taacctttca agatattgag attttaaatg atgttagagg atgtcccatt
    51721 ctgacaaaat ctccgtttaa aggaaatagt tttattagca tctcacatag tggcaattat
    51781 gtacaggcta gtgttatttt ggaggataaa aaatgatttc aagttttcat cgcccaacag
    51841 ttgcaagggt caatttacaa gctattaagg agaatgttgc cagtgttcaa aagcatattc
    51901 cactaggggt aaaaacgtat gcagttgtca aggctgatgc ttatggtcat ggtgctgtcc
    51961 aggtgtcaaa agcactccta cctcaagtgg atgggtactg tgtgtcaaat cttgatgagg
    52021 ctttgcaatt acgtcaagca ggtattgata aagagatttt aattcttggg gttttgctgc
    52081 caaatgagct aaagttggcg attactcgcc aggttacagt gacagtggct agtttagagt
    52141 ggctggcgat ggccaagcaa gaatggccag atttgaaagg gcttaaggtc catatcaaaa
    52201 ttgattcagg catgggacga atcgggcttc gctcagtaac agaagttgat aatctgattg
    52261 ctggcttgaa gagcatgggt gctgatgtag aaggtatttt tactcatttt gccacagctg
    52321 atgaggcaga tgatactaaa tttaaccagc agttacagtt ttttaaaaag ctaatagctg
    52381 gacttgagga taagcctcgt ttagtacata ctagtaattc agccacaagt atctggcata
    52441 gtgataccat ttttaatgct gttcgtttag gaattgtcag ttatggtttg aatccaagtg
    52501 gttctgatct aagcttaccg tttccactgc aagaggcttt atctctagaa tctagcttag
    52561 tgcatgtcaa gatgatttca gctggtgata cagtcggtta tggagctact tatactgcca
    52621 aaaagtctga atatgtaggg accgtcccaa tcggttatgc agatggctgg accaggaaca
    52681 tgcaaggctt ttcggtgtta gttgatggac aattctgtga aattataggg cgtgtatcga
    52741 tggatcaact gaccatacga cttcccaaag catatccttt aggaacaaaa gtcactttga
    52801 ttggcagcaa tcagcaaaaa aatatttcta caacagatat cgcaaattac cgtaatacaa
    52861 tcaattatga agttctatgc cttttaagtg accgtattcc tcggatatat taagaaaatc
    52921 acgtaaaaat aattgcattg tgcttatctt taatgttata ataaagtgag gacattagaa
    52981 agaagtgact aattaatata tgaataaaaa caaactatta agagttgcca tgctactaag
    53041 tctcttagcc ccgacagcag aaagcatgac agtgttggct caagatgtaa tgcttgagac
    53101 gcataaagca actacaaatg aaaccagtga ttcttcttca aaagaggaaa ataataaaaa
    53161 tgcagcacct acaacatcag ataaaactga ccaaggtccc cttgatgctt ctgcagaaac
    53221 aaactctaat agtcttgtta acgcggatga taaaaaaaga agcgattcta gtcagtctgc
    53281 tgtaggttct tcggacaaca aggcagaagc agaaaaccag gtagatgata aatcaactga
    53341 tcattcgaaa tcaactgatc attcgaaacc gactgaccag ccaaaaccga ctgatcagcc
    53401 caaaccatca ccatctaaag ttgatacggc acctgcttct tcattgtcga aacaactgcc
    53461 agaggcaaga actcccattc agtcgttgtc accttacgta tcagatttag atttgagtga
    53521 gatagatatc ccttctgtca acacatacgc ggcatatgta gagcattgga gtggtaaaaa
    53581 tgcctatacc caccatcttt tatctcgccg ttatggtatt aaagctgacc agattgatag
    53641 ttacttaaaa tcaacaggca ttgcctatga cagcacacgt attaatggtg agaagctatt
    53701 gcaatgggaa aagaaaagtg ggctggatgt tcgagctatc gtagctattg cgatgtctga
    53761 gagttcttta ggaactcaag ggattgcgac tttgcttgga gctaatatgt ttggctatgc
    53821 agcttttgat ctagatccga ctcaagcaag taagtttaat gatgatagtg ctattgtcaa
    53881 aatgacacaa gacaccatta ttaaaaacaa aaatagcaat tttgcacttc aagatttaaa
    53941 agcggctaag ttttcacgag gtcaattaaa ctttgcaagt gacgggggtg tttattttac
    54001 tgatactact ggtagtggta aacgtcgcgc acaaattatg gaagacctgg ataagtggat
    54061 tgatgaccat ggtggcacac cagccattcc agccgaattg aaagtgcagt catcagctag
    54121 ttttgcatct gtgccagcag gttataagct ctctaagagt tatgatgtct tgggttatca
    54181 agcttcgggt tattcttggg gacaatgcac ttggtatgtg tataatcgcg ccaaagaatt
    54241 gggttaccaa tttgatcctt ttatgggaaa tggtggagat tggaagtata aagtagggta
    54301 tgccctttca aagactccaa aagtaggtta tgctatttca tttgcacccg ggcaagcggg
    54361 cgctgatggc acttatggcc acgtatcaat tgtagaagat gttagaaaag atgggtctat
    54421 tcttatttca gagtctaact gtatcggctt aggtaagatt tcttatcgta cctttacagc
    54481 tcagcaggct gaacagctaa catatgttat tggcaagagt aaaaactaat aactaatgac
    54541 ttttcttaag gcttaatttt cttagcggga gttaggcctt ttaaactgtt ggtgtaacac
    54601 gataaagttt caagtaaata aatgattttg agacaatagc acgattaggg ctattgtctt
    54661 tttttttatt gtgatgaata tgcagtagtg acatctcatg ttgtctccta acataattat
    54721 ggagcttata acgtgttaca tgttttgtga atgaagtaat gattgaatca gccttagtaa
    54781 taactatcct aaggctagct ttatctcagt aatagtgttg tagaggaatt cttttatcag
    54841 agatatcctc attatcaatc caggcttatt actagtgtct tagctcacat agtggagcta
    54901 tttaacagac aattggacca ttggaaacaa tcttgacaaa ataatcacaa agtgatagat
    54961 taagttcagt taataaaaaa gttagcttat tcataaaaat ttttagaaag ttgattgaaa
    55021 atgaaaaaaa tcagcaaatg tgcgtttgtg gcaatatctg cccttgttct cattcaggct
    55081 actcaaactg taaaatcaca agagccttta gttcagtcac aactcgtgac aacagtagct
    55141 ttaactcagg ataatcgact tttagttgaa gagataggcc cttacgctag tcaatcagct
    55201 ggaaaagagt attataaaca tattgaaaag gttattgttg ataatgatgt ctatgaaaaa
    55261 agcctggaag gcgagcgaac ctttgatatt aactaccagg ggattaagat caatgctaac
    55321 cttattaaag acggtaagca tgaattgact attgttaata aaaaagatgg tgatatctta
    55381 attaccttta ttaaaaaggg cgataaagtg acctttattt cagctcaaaa attaggaaca
    55441 acagatcatc aggattcatt aaaaaaagat gtgctcagtg ataaaccagt gccacaaaac
    55501 caaggcacac aaaaagttgt taaatctggg aaaaatactg ctaacttgtc attaataaca
    55561 aaattgagtc aagaagatgg tgcaatttta tttccagaaa ttgatcgtta ttctgataac
    55621 aaacagataa aagcattgac tcagcaaatc acaaaggtta cagtcaatgg tacagtttat
    55681 aaagatctta tttcagattc tgtaaaagat actaatggct gggtctcgaa tatgacaggg
    55741 cttcatcttg gaacaaaagc tttcaaagat ggagaaaata caatcgtgat atcctcaaaa
    55801 ggatttgaag acattaccat taccgttacc aagaaagatg gtcaaatcca ttttgtatct
    55861 gccaaacaaa aacaacatgt gactgctgaa gacagacaat caacaaagtt ggatgtcacc
    55921 actttggaaa aagctatcaa agaagcggat gcgattattg ctaaagaaag caacaaagac
    55981 gcggtcaaag atctggctga gaaacttcaa gtcatcaagg attcttacaa agaaattaaa
    56041 gatagtaagc tactcgacga tactcatcga ctgttaaaag ataccatcga gtcttatcaa
    56101 gcaggtgagg tttctattaa caatctcaca gaaggaacct atacgctaaa ctttaaagct
    56161 aataaagaaa actcagaaga gtcctccatg cttcaaggtg cttttgataa aagagccaaa
    56221 ttagtggtta aagcagatgg tacaatggaa atttccatgc ttaatactgc tttgggacaa
    56281 tttttgattg acttttctat tgaaagcaaa gggacctacc cagcagcagt gcgtaaacaa
    56341 gttggccaaa aagatatcaa tggtagctat attcgaagtg aatttaccat gcctattgat
    56401 gatttggata aattacacaa aggtgctgtt ttggtatcag ccatgggagg tcaagaaagt
    56461 gatttaaacc actatgacaa atacaccaaa cttgacatga cctttagtaa gaccgttacc
    56521 aaaggctgga gtggttatca ggtagaaact gatgataaag aaaaaggggt tgggactgaa
    56581 cgtcttgaaa aagttttagt taaacttggc aaagatttag acggcgatgg taaattatca
    56641 aaaacggaat tagaacagat tcgaggtgag ttgcgtctag accattacga gttaacagat
    56701 atttctttat tgaaacatgc taaaaatatt acagaactac atctggatgg aaaccaaatt
    56761 acggaaattc caaaagagtt atttagtcaa atgaagcaac ttcgatttct taacttaaga
    56821 agtaatcatt taacttatct agacaaagat acatttaaaa gcaatgctca attaagagaa
    56881 ctctacttat caagtaactt tattcactct cttgaaggag gactattcca gtcgcttcat
    56941 cacctggagc aacttgatct ttccaagaat cgtattggcc gactttgtga taacccattt
    57001 gaaggattgt ctcgcctgac ttcattaggt ttcgcagaaa atagtcttga ggagatacct
    57061 gaaaaagcgc tagagcctct aacatcactt aactttatcg acttatctca aaataattta
    57121 gcactactgc caaaaacaat agaaaaattg cgcgccttaa gcactattgt ggcaagtaga
    57181 aatcatatta ctcgtattga taatatttca tttaaaaatc ttcctaaatt atctgtactc
    57241 gatttatcaa ctaatgaaat ttcaaatctt ccaaatggta tatttaaaca gaataaccaa
    57301 ttaacaaaac ttgatttttt caataacttg cttactcagg ttgaagaatc agtatttcca
    57361 gatgttgaaa cgcttaattt agatgtgaag ttcaatcaga taaaaagtgt gagtccaaaa
    57421 gtaagagctc ttatcggaca acacaaactg actccacaaa aacatattgc aaaacttgaa
    57481 gcttccttag atggcgaaaa aataaaatat catcaagctt tcagtctttt agatttgtat
    57541 tattgggagc aaaaaacaaa ttctgccatt gataaagaac tagtgtctat tgaagaatat
    57601 caacaattgt tacaagaaaa aggttcagat actgtctctt tacttaatga tatgcaagtc
    57661 gattggagta ttgtgattca gttgcaaaaa aaagcttcca atggacagta tgtgacggtt
    57721 gacgaaaagc ttctctcaaa tgatccgaaa gatgacttaa cgggagagtt ttctttaaaa
    57781 gatccaggta catatcggat tcgcaaagct ttaataacaa agaaatttgc tactcaaaaa
    57841 gaacatatct atttgacatc taatgatatc cttgtggcga aaggaccaca tttacatcag
    57901 aaagatttag ttgagaaagg ccttagagca ttaaatcaaa aacaattgcg tgatggtatt
    57961 tactatttaa atgccagcat gttaaaaact gacttagcat ctgagtccat gtcaaacaag
    58021 gctattaatc atcgagtgac tttggtagtt aaaaaaggtg tttcctattt agaagttgag
    58081 tttagaggga taaaggttgg taaaatgtta ggctaccttg gtgaattgag ctatttcgta
    58141 gatggttacc aaagagattt agctggtaaa ccagttggtc gaacaaaaaa ggcagaggtt
    58201 gtgtcttatt tcacggatgt aactggccta ccattggcag atcgttatgg aaaaaactat
    58261 ccaaaagtgc tgcgtatgaa attgattgaa caagcgaaga aagacggact tgtgccatta
    58321 caggtctttg tgcctatcat ggatgccatt tcaaaagggt ctggccttca aaccgttttt
    58381 atgcgtttag actgggcaag ccttacaaca gagaaggcaa aggttgtcaa agaaactaat
    58441 aatccacaag aaaatagcca tctaacttca acagatcagt tgaaaggacc tcaaaatcgt
    58501 caacaagaaa aaacacctac aagtcctcct tcagcagcta ctggtattgc taacttaact
    58561 gatctcctgg ctaaaaaagc aaccggccaa tcaactcaag aaacttctaa gacagatgat
    58621 actgataagg cagagaaatt gaagcagtta gtgcgtgacc atcaaacatc aattgaaggt
    58681 aaaacggcaa aagatactaa gactaaaaaa tctgataaga aacatcgttc caatcaacaa
    58741 tcaaatggtg aagaaagtag ctctcgctat cacttaattg caggtctatc tagctttatg
    58801 atcgtagctc tgggattcat tattggtcga aagacattat ttaaataaga aacttagtac
    58861 caagtgaaat aacaaaaaaa agctagtcag caagagctaa aaacatacct atttccgaca
    58921 ggactcctga tacaggttga agtagtcgca agataggtgt gtttttcaca tttggagatg
    58981 ttataaaatg ggaatcattt aaaaaatgaa ataagatgtt taagaaaaga tagacaagag
    59041 gagcatatga caaaggtagt aataaagcaa ttgttgcagg taatagtagt gttcatgata
    59101 agtttatcga caatgacagg tgttgtgtat gcagataaag gtcaaattta tggatgtatt
    59161 attcagagaa attatcgtca tccgatatct gggcagatag aagatagcgg aggggagcat
    59221 tcctttgata ttggtcaagg tatggttgaa gggactgtct atagtgatgc catgctagaa
    59281 gtatctgatg ctggaaagat cgttcttact tttcgtatga gcttagctga ttattcgggc
    59341 aattatcagt tctggataca acctggagga actggaagct ttcaggcagt tgattacaat
    59401 atcacccaaa aaggtactga taccaatggg acaacactag atattgctat tagtttgcct
    59461 actgtaaata gtatcattcg aggaagcatg tttgttgaac ctatgggcag agaagtggtc
    59521 ttttacctgt cagcttcaga gttaatacaa aagtattccg gtaatatgtt ggcccagctt
    59581 gttactgaaa cagacaattc tcaaaatcaa gatgtaaaag acaatcaaaa gcctgttgat
    59641 acaaaactag gagaaagtca agatgagtct cacacaggtg ctatgataac tcagaataag
    59701 cctaaagcca actcatcaaa taacaagagt ctatcagata aaaaatttct tccttctaag
    59761 atgggcttaa cgacttcttt agagttaaaa aaagaagata agtttcggtc taaaaaagac
    59821 ttatcaatca tgatttacta ctttccaact ttttttctga tgttaggagg gtttgctgta
    59881 tgggtttgga aaaagaggaa aaagaggaaa aaaaatgata aaacgatgta aaggaattgg
    59941 tctagcctta atggccttct ttttggtagc ttgtgtgaat cagcacccta aaacggctaa
    60001 agagactgaa cagcagagaa ttgtagccac ttcggttgct gtggttgata tctgtgaccg
    60061 tttaaattta gacctcgttg gggtttgtga tagtaaatta tatacccttc ctaaacgcta
    60121 tgatgctgtt aagcgtgtgg gtttacccat gaatcctgat atagagttga ttgcttcttt
    60181 gaaaccaact tggattttga gtcccaattc tttacaagaa gatttggaac ccaagtatca
    60241 aaaattggat actgagtatg gttttttgaa cttacggagt gttgagggca tgtaccagtc
    60301 cattgatgat ttagggaacc ttttccaacg tcaacaagaa gcaaaagaat tgcgccagca
    60361 ataccaggac tattatcgtg ctttccaagc taaacgtaag gggaagaaaa agcctaaagt
    60421 gcttattctt atgggcttgc caggtagtta tttggtggcg acgaaccaat cttatgtagg
    60481 gaatcttttg gacttggcag gtggtgagaa tgtttatcag tcagatgaga aagaatttct
    60541 atcagctaat cctgaagaca tgctggctaa ggagcctgac ttgattttac gaacagctca
    60601 tgccattcca gacaaggtaa aagtgatgtt tgacaaagaa tttgctgaaa atgatatttg
    60661 gaaacatttt acggcagtca aggaagggaa agtctatgat ttggacaata ccctgtttgg
    60721 catgagtgct aaattgaact acccagaagc cttggacacc ttaacacagc tttttgacca
    60781 cgtgggagat catccgtaac atgacagcat cagatttaca aagggatcaa tccctactgg
    60841 ctaaaaaacg tttcagaagt ggtctttatc tagttctttt aattctcagc ctcctatttt
    60901 tagcggttat tgccttatcc cttggtggtt tggcggtttc ttatggggca attgtcaagg
    60961 gactgtttgt ggcttatgac ccccaagtgg ctttgattta tgatttgcgt tttccaagaa
    61021 ttgtcattgc tttattagca ggagcaggga tagctgtttc gggagttctt tttcaagcag
    61081 tgttgaaaaa tcctatttca gaccctgcta ttatagggat ttgtagtggt gctagtttta
    61141 tggttttagt ctctagttta cttctgccgc agttgctgct gtatggtcca atcgtatcct
    61201 ttttaggagg cggagtgtct ttcctgctga tttatggttt agcatggaag aaagggctta
    61261 atcctattcg gcttattcta acagggattg ctattaatgc tttatttatg gggttatcaa
    61321 ctgctttaac cagctttttc acctcagcta gtcccatggt caatgctctt ttagcaggtc
    61381 atattagtca aaaaacatgg gctgatgtag gggttttatt cccttataca ttcattggct
    61441 tgttactagc tttgttattg tcaaaaacct gtaaccttct tcttttagat gatcaggtga
    61501 ttcgtcattt aggaatcgat gctacagcgt tacggttggg aatttccttg gttgctgttt
    61561 tattggcttc ggtagccact tcgatcgttg gagtggtttc tttcctaggc ttgattgtcc
    61621 ctcatatgag ccgcttgctg gttggaagta agcaccaaat cttaattcct ttttcagctt
    61681 tgcttggagc ctttgtcttt ttgctagctg atactttagg aagaagtctt gcttacccat
    61741 tggaaattag ccctgcgatt ataatgagta ttgtaggcgg gccttacttt atttacctgc
    61801 taaggaggtc tgatattata tgagtaagaa cagcagtcat attcaggtgc aaaacctttc
    61861 ctttgcttat gaggaaaaac ttgttttaga tgacctgacc tttagcattc caaaagggaa
    61921 aattaccact attatggggg caaatggcag tggcaagtca accttattac aattattaac
    61981 caaaaacctt ccgttaaaac aagggcaggt ttggcttgag caggaagaat tagcaacgat
    62041 ttctctcaag gcttttgcga aaaaagtggc agtggtacac caataccatc aagtggtcga
    62101 aggtttgtta gtgggtgaat tggtaaccat ggctaggctt gcccgtcgtt ctttttttaa
    62161 aactactacc aaagaagatg aggaacgcct tgcttgggcc ttagaagtaa cggctttgag
    62221 tgattatgtt tatcgtgaca tccaacacct ttctggtggt gaacagcaga gggtttggat
    62281 tgctatggcc cttgcccagg atacagatat tattttttta gatgagccaa cgacttattt
    62341 ggatattaag taccagcttg acattctcaa gctgattact aaaatcaacc aagagctagg
    62401 cttaacgatt gtgttagtat tacatgacat caatcaggcc ttgtctcttt cagaccatct
    62461 tattggactg aaagatgggc gactttatgc ccaagggcaa ccaagagacc tccttgatca
    62521 acagtttatc agagatgtct ttggtgttga attgcccttt gttgagagaa atggtcaaca
    62581 gtttgtcctc acttcattgg tcaatgaaac caatgatatt agaactcaaa ggagagatag
    62641 gaacaagaac agatgatgga aacagaagat acaatatcaa ggggaaaaag gaaaagactg
    62701 ttaaaacgat tacgtgaacg aattgcacca aaaaggtatt tgctttatgt gtcagccttt
    62761 ttatcttggt tacaatttgt gatgaggatg atcagttttt acctcattgc caaaacgttt
    62821 tcgaccttta ttttgggtca tgctattgcc ttaggacgct tggcaggttt actcctactt
    62881 ttaaatgtgg taggctttgt tcttgctata ttaggcaagc aactgcaagg gatcgcttca
    62941 caatttgcta gagattcact caaacaatct ttctttgagg cttttattga tttagacggg
    63001 caatttgatg ctcatgccag tgatgctgat attttaacgt tggcttcaca ggggattgat
    63061 agtttggata cttattatgg ttactatttg tctttgtcta tgagaaccaa gtggaactgc
    63121 acaactatta tgatactagt ttttttaatt tatccattgg caggccttgt ctttttagga
    63181 gttctgcctc tgattccact ttcaatcgtt gctatgcaaa agcggtctaa gcaaattatg
    63241 agtcattatt ggtcttctta tatggatgtt ggtaatttat ttatggatga cttaaaaggt
    63301 cttaatacac tgtattctta tcaagcaaca gaacgttacg agcaagaatt ttcgggtaag
    63361 gcagaacagt ttcgaaaggc taccatgtct ttgcttggct ttcagttaca agcagttggt
    63421 tatatggatg cagttatgta tctgggaatt ggtttgtcag gttttttagc cgttcaagct
    63481 ttggcaacag gtcagttatc tttttttaat ttcctctttt ttctcttgat tgctacagaa
    63541 ttttttacac cgattcgtga gcagggttat ggcatgcact tggtcatgat gaataccaaa
    63601 atggctgacc gtatctttag tttcttggat agtgttccag caaggaaaga taacaagagt
    63661 aaaacagcaa taaactttaa ccagattgac ctccaaaata tttctttagc ttatgagaaa
    63721 aaaacagtgc ttagtggggt taccatgaca ttaacgaagg gccaactaac agctatcgcg
    63781 ggggtgtcag gacaaggaaa aacaagtcta gctcaactcc tcttgaaacg ccagtctgca
    63841 acgactgggc atattttatt tgacggttta gacagtgaca atttgtcgca agaaactatc
    63901 aaccagcagg ttctttatgt atcggaccaa tctaccttat tgaaccgtag catttacgat
    63961 aatttaaggt tagccgcaaa tctctctaaa aaagaaatct tagattggat agatcaacat
    64021 ggtttgttaa gcttcatcaa ctggctacca gatggccttg acacaatagt tggtgaaaat
    64081 ggtaacctgt tatcaccagg ccaaaagcaa caggtgattt gcgcaagagc tctattaagt
    64141 aagaggtctc tttatatctt tgatgaggca acatctagtc tagatgcaga aaatgaacgt
    64201 attattgaca atttaataac gagattagct aagacggcaa tagttattgt gattactcat
    64261 aagatgtctc gactgaaagg agctaaccaa gtactctttt taagcacagg gcagcctgct
    64321 tgtttaggca aaccttgcga cctttatcgg gaccaaccaa cttatcgtca cctagttgat
    64381 actcaagcaa gactggaggc aagtatttat ggctaaacct aacagatcta ccttaagcct
    64441 ggtttggcgt ttattaaccc taatgaaaac tctgctacct tggattatct tggctgttgg
    64501 ctttgctgtt atgggttttg tcatcacggt aagtattcca actggaatag cttatttagg
    64561 actactagct attagacaag aagtgattcc aatattagct ttatatcttt tgattgctct
    64621 agccttttta agaggttttg ttcgttatgg agagcattat tttggtcatt ttgttgcttt
    64681 tcatagttta gcagctttta ggaacttgat ctttaagaaa ctaagagctc tttctccagc
    64741 ttgcttggat agtcaagaca gtggttattt gcttaaaatg attggagaag atattgaggc
    64801 attagaagtt ttttttgccc acacaatcgc gcctatttgt acagcaatat tgtctgcagg
    64861 tttaatgttc tggtactttt gtcaaagtag ttggcagtta gccttattag ctttggcaac
    64921 ctatgcttgt ttagccattg ttatacccat ttattttgct aatattttac aggttttact
    64981 aaaaagccaa aatgaaggtc gaaaagatta cctgtcttat tttttagaga gtttacgatc
    65041 agtcaaagat cttttgcaat ttcaggtatt agacgagcaa tttgaacgat taataaaaaa
    65101 aagtaatcat gtaaatgctc ttgatcgtaa cgtagcgcaa gctcaatttt tgcaaatggc
    65161 attgactttt ttctggcttg gcttaatgat cttagcattt tcttatatgg tttttgatgg
    65221 gatatgccat gacagcttat catttgataa aggcttatta acttttattg ctttcactgc
    65281 ttcgttttct ccttttttag aactaggacg tttgccatta ggctttaagc gtgctatgaa
    65341 tgcggctcga aatatttttg accttctaga cgaaaatgtc atagtagacg aaggcacaaa
    65401 acagatagat cgtttaagga gtgtttcttt tgaggacctc agttttgctt atccaaagcg
    65461 ccaagagctg gtttttaagg atttatcagt tacttttcaa gaaaagggga ttattggcat
    65521 taaaggcgaa tcaggatctg gtaaatcaac tttggtgaaa ttaattatga aatggtataa
    65581 ttggaagaca ggagatattt ttcttaatga taggaatagt tgcttactaa atgctgctaa
    65641 attacaagat actattgctt atgtgccaca aacagcgcag cttttccaac agtctatccg
    65701 tgaaaatctt acctttggcc gtcaagatat ttcagatgag tccatttgga atttagctga
    65761 ggcttgtggt atgaaagaca gactgttagc ttgtaaggaa ggtttggata cgattatcaa
    65821 gagtccttct gacttttcag ctggagaagg tcaacgttta gagttgatgc gagctttatt
    65881 gaaagatgcg agttgctata tttttgatga acccacgtca aatttagatt ctctaaatga
    65941 agctatcttg cttgatttaa ttaaaacaca ttgtcaagga ttggtcttct taatttctca
    66001 caggccatca actctagctt gtgctgatca tctattttgc gtaaaaaatg gtttcctaaa
    66061 agaggtgaat aaaaaatgaa acagttaaca ataaaagata ttatgataac aggcgcattt
    66121 gccgcgctct actttatttg tgttggtcta ggcacgttta ttaacatctt ttttgatcgc
    66181 tcaggaaata tgttatatgc ccctgccttt gcagctttac tggggggaac aatttatttt
    66241 cttttgattg ctaaattgca aacatttggg ccaataacat tattaggatt gatgatggga
    66301 ggttttttct tccttagtgg tcactttttt gccgcgatgt ttcccagcat tattttcggt
    66361 ttaatagcgg atattattgc ttctttagga aaatacaagt caaggttttt taatgaccta
    66421 tcttatatgg tttttgcttt tgtcaatagt ggccctattt tgctgatgtg gttgttgaaa
    66481 gatgcctatg ttgaaagttt gttagcccgc ggtaaaagta tgacctatgt caatcgcatt
    66541 atgtatgatt ttagtttagg gcatgttatt tggtttgtag gaattgttct tgcaggagcc
    66601 ttattagggt cagtttttgc acattattta ctaaagaaac attttatcaa atcaggattg
    66661 ttatcatgag gcttgatgtt cgcaccaaac tgcttttgtt ggtacttgcc aatgcctgct
    66721 tcttttttcg tgttgatggc tttttagaat ttataattgt tatttttctc ttattacttt
    66781 tgtctgcttt aaataagaaa aagctagcgt tcaagttggc ggttgtttat ctgttaatga
    66841 tcggtctatc tgtaatcccg ctatctattt tcccttctta tcttgatcac ttattgagtt
    66901 ttgtctcaat agcaggaagg ttagttttcc cttctttact agcaggttta attactatta
    66961 agacaactac catctacgaa ttggttcatg gattacgcaa atggcatttc ccagaagtct
    67021 ggctattgac cttagccgtt atgtgccgtt tcataccaat gattagacaa gaatgttgtg
    67081 ttattcatcg ctctttaaca atcaggggga ttattttaac aaaatggtct attttgatca
    67141 gacctaaaca atacttggag tatttaatgg ttccattgct tttatctttg ataagaagta
    67201 gtcaagaact aactatcgct agtctaacta aaggactagc agtcaacaaa ggcaccagtg
    67261 aatgctttag ctcacactta acatggaaag attggggggt gcagatttgg attactgtta
    67321 tcataatcat cacgatactt caatgatttc agcagaacaa cttgttttta cctatcatga
    67381 tcaaaaaaat ccagcttgtc aggtatcgac ttgtcaaatt gcctctggac aattcattgt
    67441 tttgtgtgga ccttctggtt caggtaaatc taccttttta aaatttctta atggcataat
    67501 tcctgattat tatgctggaa aatatgaagg tagactagat gtggctgatt gccaagcagg
    67561 cagagacagt gttgaaacat tttctagatc tgtggcctct gtttttcaaa atccagccag
    67621 tcagtttttc tatcgcgaag tccaacacga actggtcttt ccctgtgaaa atcaaggtct
    67681 agatgcaaag gttatcatga agcgtctttg gactttagca gaagattttg cttttgcaga
    67741 gctccttaac aaggatatgt ttggattgtc aggagggcaa aaacaaagag ttgctattgc
    67801 aacggccatt atgcagggta ctaatattat gctttttgat gagccaactg ctaacttaga
    67861 tagtgcaggc atagctgctg ttaaagccta tcttacccaa ttaaaagcag caggaaaaac
    67921 cattattgta gccgagcatc gcttacatta cttgatggat ttggcagata actttttcta
    67981 ctttaaaaat ggtagattaa cagataagtt aacaacacaa aatttgctag ccttgacaga
    68041 tgaacaacgg caagatatgg gactacgtcg cttagacttg tctgacctaa aacctgtgtt
    68101 agctggtaag attgagagtc aacattatcg cccagatgat agcctgtgta ttgagcatct
    68161 aacagttaga gcgggaagca aaatacttag atgtattgaa cagcttagtt ttgctgcagg
    68221 aagtatttct ggcattacag gatcaaacgg gcttggaaaa tcgcaattag tttattatat
    68281 agctggtatc ttagacgata aaaaagcaac tattaagttt caaggcatac ctttatctgc
    68341 caagcaacgt ttatcaaaga ctagtattgt cttgcaagaa gtttctttgc aactatttgc
    68401 agaatcggtt tcaaaggaag tcaacttggg ccatgaacga catccacgga cgacagaagt
    68461 aatagagcgg ttatctttaa cgactctttt agaacgtcat ccagctagtt tgtcaggagg
    68521 tgagcaacaa agagtgatga ttgccgctag tcttttggct gataaagata tcttaatttt
    68581 tgatgagcca agtagcggac ttgatttgtt acaaatgaag gctttagcta atcttctcat
    68641 gcagctgaag acccaacata aggttgtcat cctcatttca catgatgaag aacttctaag
    68701 tagtgtctgc gataccattt atcaaatgct accttaacga gcccctagaa ctgtttaaaa
    68761 gtactaaaag gcttttatct gaaaataaat aggaactctt gtataataga tacaagagtc
    68821 agaacgtaga caactccagt tttatgctca aaaagcatgc atagctctgc tgatttgaca
    68881 ttcggtttcc gatttttaca tataaagtga gccaaaacag atgctttttg ttgtggtaaa
    68941 agagtggcgt caatacgaga ttgacgccac tcgggatttt tgagacctca ggctcaaaaa
    69001 taaaggcatg gaattccaaa gaacgtcgct gccgtaagca ccacctaagg aaagtatcac
    69061 gacaaacttt gtcttcaatc tgacaagagt ttttgtgaag ggaaaaagat aatgatatta
    69121 acagctccta tgtccaactt aaagggattt ggaccaaaat cagcagaaaa atttcagaaa
    69181 ttagatattt atacagtaga agatttactg ctttattatc cgtttcgcta tgaagatttt
    69241 aaatcaaaat ctgtttttga tttagtggat ggtgaaaaag cagtcattac aggcttagtc
    69301 gttactccag ctaatgtaca atattatggt tttaaacgta accgtttaag tttcaaattg
    69361 cgtcaagggg aagctgtctt aaatgttagt ttttttaatc aaccctattt agctgataaa
    69421 atagaacttg gtcaagaggt agctgttttt ggtaaatggg atgccactaa atcggctatt
    69481 actgggatga aggttttagc tcaagttgaa gatgacatgc aacctgttta tcgcgtagct
    69541 cagggaattt cacagtctac tttgattaaa gctattaagt cagcttttga aatcgatgcg
    69601 catttggaat tgaaggaaaa tttaccagct actttattgg aaaaataccg attgatgggt
    69661 cgtagtcagg cttgtttagc tatgcatttc ccaaaagata tcacagagta taagcaagcg
    69721 ctccgtcgga ttaaatttga agaattattt tactttcaaa tgaaccttca agttttgaaa
    69781 gccgaaaata gatctgaaac aaatggtttg cctattcttt atagtaaaca tgctatggag
    69841 acaaagattt cctctttacc ctttattcta acaaatgctc aaaagcgctc tttggatgac
    69901 atattatctg atatgtcatc gggagctcat atgaatcgtt tattgcaagg agatgtagga
    69961 tcaggaaaga cagtcattgc tggtctatca atgtatgcag cttatacagc aggttttcaa
    70021 tcggctttga tggttccaac ggaaatccta gctgaacaac actacactag tctgcaagag
    70081 ttatttccag atctatcaat tgctatatta acttcgggta tgaaagccgc tgtcaagcgt
    70141 acggttttag cagctattgc aaatggctcg gttgatatga ttgtaggaac tcatgctctt
    70201 atccaagact cggtacagta ccataaactg gggcttgtca ttacagacga gcaacatcgt
    70261 tttggtgtta aacagcgtag aattttccgt gaaaagggag aaaatcctga tgttttaatg
    70321 atgacagcca ccccaattcc ccgaactcta gcaatcacag tttttggaga aatggatgtt
    70381 tctgttattg atgaattacc tgccggtcgt aaacctatta tgacacgctg ggtgaaacac
    70441 gagcagctag ggactgtgtt ggaatgggta aaaggtgaat tgcaaaaaga tgctcaagtg
    70501 tatgtcattt caccgttgat tgaagaatca gaagctttag atttaaagaa tgcagtagca
    70561 ttgcatgccg aattatctac ttattttgaa ggaattgcta aggttgctct tgtacatgga
    70621 cgtatgaaaa atgatgaaaa agatgccata atgcaagatt tcaaggataa aaaaagtcat
    70681 attttagtat ccacaacagt tattgaagta ggggtaaatg tcccaaatgc aacgatcatg
    70741 attattatgg atgccgatcg ttttggatta agccagttac atcaacttcg tgggcgtgtt
    70801 ggtcgtggac ataaacaatc atacgctgtt ttagtggcta atcccaaaac ggattcgggg
    70861 aaaaaacgaa tgacaatcat gacagaaacg acagatggtt tcgttttggc tgagtcggat
    70921 ttaaaaatgc gtggttctgg tgaaatcttt ggtactcgtc agtctggaat tccagagttt
    70981 caagtagctg atatcgttga ggattatcct attttagaag aagcacgcaa agtttctgca
    71041 gcgattgttt ctgatcctaa ctggatatat gaaaaacagt ggcaattagt agcaaaaaat
    71101 attagaaaaa aagaagttta tgattaactt aaaacaagtc gttgttttac aaatatttag
    71161 ttagttttga gataaactgt tataaagtat aaagaggtca ctatttctgg ccttttttac
    71221 ttatgcttta cgatgagact gctatgtgaa gcagtattaa cccattttca gtataacttt
    71281 tttattgcta aaataatcat attattaaaa ttctt
//
LOCUS       DAUGSW010000007        64383 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUGSW010000007 DAUGSW010000000
VERSION     DAUGSW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64383
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.007"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            213..1445
                     /locus_tag="VIB18_000514"
     CDS             213..1445
                     /locus_tag="VIB18_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8765543.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            1613..2794
                     /locus_tag="VIB18_000515"
     CDS             1613..2794
                     /locus_tag="VIB18_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8765544.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSSKQQHFKATKKQSYLERVEDFINHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(2946..4364)
                     /gene="sufB"
                     /locus_tag="VIB18_000516"
     CDS             complement(2946..4364)
                     /gene="sufB"
                     /locus_tag="VIB18_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEQ8765545.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(4357..4836)
                     /locus_tag="VIB18_000517"
     CDS             complement(4357..4836)
                     /locus_tag="VIB18_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEQ8765546.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(4823..6049)
                     /locus_tag="VIB18_000518"
     CDS             complement(4823..6049)
                     /locus_tag="VIB18_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8765547.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(6080..7342)
                     /gene="sufD"
                     /locus_tag="VIB18_000519"
     CDS             complement(6080..7342)
                     /gene="sufD"
                     /locus_tag="VIB18_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEQ8765548.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKISANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHVLKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(7437..8207)
                     /gene="sufC"
                     /locus_tag="VIB18_000520"
     CDS             complement(7437..8207)
                     /gene="sufC"
                     /locus_tag="VIB18_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEQ8765549.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(8329..9498)
                     /locus_tag="VIB18_000521"
     CDS             complement(8329..9498)
                     /locus_tag="VIB18_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEQ8765550.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLILGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(9505..10266)
                     /gene="mecA"
                     /locus_tag="VIB18_000522"
     CDS             complement(9505..10266)
                     /gene="mecA"
                     /locus_tag="VIB18_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEQ8765551.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESELLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(10412..11251)
                     /locus_tag="VIB18_000523"
     CDS             complement(10412..11251)
                     /locus_tag="VIB18_000523"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEQ8765552.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(11317..13242)
                     /locus_tag="VIB18_000524"
     CDS             complement(11317..13242)
                     /locus_tag="VIB18_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEQ8765553.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRTGHLSAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGKEPV
                     DVSTSKKNKIVALETKISRRRTLLQLLFGKVIPLVEVGFLLWQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKMTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     IPAEKRKNNSVQGLGCLLLILNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            13440..15008
                     /locus_tag="VIB18_000525"
     CDS             13440..15008
                     /locus_tag="VIB18_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8765554.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYAEAKSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAVLG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIATIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQIQIAEVSNV"
     gene            15001..15741
                     /locus_tag="VIB18_000526"
     CDS             15001..15741
                     /locus_tag="VIB18_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765555.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     ITEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            15883..15999
                     /locus_tag="VIB18_000527"
     CDS             15883..15999
                     /locus_tag="VIB18_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEQ8765556.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(16225..17235)
                     /gene="gap"
                     /locus_tag="VIB18_000528"
     CDS             complement(16225..17235)
                     /gene="gap"
                     /locus_tag="VIB18_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEQ8765557.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(17583..19661)
                     /gene="fusA"
                     /locus_tag="VIB18_000529"
     CDS             complement(17583..19661)
                     /gene="fusA"
                     /locus_tag="VIB18_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEQ8765558.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(20028..20498)
                     /gene="rpsG"
                     /locus_tag="VIB18_000530"
     CDS             complement(20028..20498)
                     /gene="rpsG"
                     /locus_tag="VIB18_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEQ8765559.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFNAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(20519..20932)
                     /gene="rpsL"
                     /locus_tag="VIB18_000531"
     CDS             complement(20519..20932)
                     /gene="rpsL"
                     /locus_tag="VIB18_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEQ8765560.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(21140..23761)
                     /locus_tag="VIB18_000532"
     CDS             complement(21140..23761)
                     /locus_tag="VIB18_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEQ8765561.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINNLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQETLAALQTKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPPLMGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESK"
     gene            complement(23752..24591)
                     /gene="purR"
                     /locus_tag="VIB18_000533"
     CDS             complement(23752..24591)
                     /gene="purR"
                     /locus_tag="VIB18_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEQ8765562.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(24857..25795)
                     /locus_tag="VIB18_000534"
     CDS             complement(24857..25795)
                     /locus_tag="VIB18_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEQ8765563.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVEEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(25785..27056)
                     /locus_tag="VIB18_000535"
     CDS             complement(25785..27056)
                     /locus_tag="VIB18_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEQ8765564.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEEINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLNASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            complement(27058..27690)
                     /locus_tag="VIB18_000536"
     CDS             complement(27058..27690)
                     /locus_tag="VIB18_000536"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEQ8765565.1"
                     /translation="MSKVALFAGGNLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(27683..28345)
                     /locus_tag="VIB18_000537"
     CDS             complement(27683..28345)
                     /locus_tag="VIB18_000537"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEQ8765566.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(28355..29227)
                     /gene="rsgA"
                     /locus_tag="VIB18_000538"
     CDS             complement(28355..29227)
                     /gene="rsgA"
                     /locus_tag="VIB18_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEQ8765567.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITIFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(29651..30523)
                     /gene="rsmA"
                     /locus_tag="VIB18_000539"
     CDS             complement(29651..30523)
                     /gene="rsmA"
                     /locus_tag="VIB18_000539"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEQ8765568.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVED
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(30637..31227)
                     /gene="rnmV"
                     /locus_tag="VIB18_000540"
     CDS             complement(30637..31227)
                     /gene="rnmV"
                     /locus_tag="VIB18_000540"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEQ8765569.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYNVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHARFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(31199..31990)
                     /locus_tag="VIB18_000541"
     CDS             complement(31199..31990)
                     /locus_tag="VIB18_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEQ8765570.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD"
     gene            32275..33105
                     /locus_tag="VIB18_000542"
     CDS             32275..33105
                     /locus_tag="VIB18_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEQ8765571.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDSSERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNDNCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            complement(33216..34154)
                     /locus_tag="VIB18_000543"
     CDS             complement(33216..34154)
                     /locus_tag="VIB18_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8765572.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDEGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(34176..35090)
                     /locus_tag="VIB18_000544"
     CDS             complement(34176..35090)
                     /locus_tag="VIB18_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEQ8765573.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGNISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPYTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIADKDLEKAKALQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(35102..35764)
                     /locus_tag="VIB18_000545"
     CDS             complement(35102..35764)
                     /locus_tag="VIB18_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEQ8765574.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKHYFKSGMRLGLIELGIMTICLLDLF
                     LIRNQSGLVFQGVKVLCVAVLFLVVILFLYAYPQAVKRDLSLSTLFKRSFLLAGLFFP
                     WSFAFLAFICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(35921..36751)
                     /locus_tag="VIB18_000546"
     CDS             complement(35921..36751)
                     /locus_tag="VIB18_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8765575.1"
                     /translation="MMKKKLTASDILTTVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVIQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(36764..37651)
                     /locus_tag="VIB18_000547"
     CDS             complement(36764..37651)
                     /locus_tag="VIB18_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8765576.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(37757..39076)
                     /locus_tag="VIB18_000548"
     CDS             complement(37757..39076)
                     /locus_tag="VIB18_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8765577.1"
                     /translation="MNMKKLASLAMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(39125..39829)
                     /locus_tag="VIB18_000549"
     CDS             complement(39125..39829)
                     /locus_tag="VIB18_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEQ8765578.1"
                     /translation="MPDKPIKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLMAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEAVKS"
     gene            complement(40103..40237)
                     /gene="rpmH"
                     /locus_tag="VIB18_000550"
     CDS             complement(40103..40237)
                     /gene="rpmH"
                     /locus_tag="VIB18_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEQ8765579.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(40551..41465)
                     /locus_tag="VIB18_000551"
     CDS             complement(40551..41465)
                     /locus_tag="VIB18_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEQ8765580.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISGKTVYKADKKATRGVPEDINQKNVPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDASNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(41477..42304)
                     /locus_tag="VIB18_000552"
     CDS             complement(41477..42304)
                     /locus_tag="VIB18_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8765581.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVLQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(42270..42629)
                     /gene="rnpA"
                     /locus_tag="VIB18_000553"
     CDS             complement(42270..42629)
                     /gene="rnpA"
                     /locus_tag="VIB18_000553"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEQ8765582.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGLESEEKH"
     gene            complement(43169..43909)
                     /locus_tag="VIB18_000554"
     CDS             complement(43169..43909)
                     /locus_tag="VIB18_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8765583.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(43913..45196)
                     /locus_tag="VIB18_000555"
     CDS             complement(43913..45196)
                     /locus_tag="VIB18_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8765584.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSIIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            complement(45193..46539)
                     /locus_tag="VIB18_000556"
     CDS             complement(45193..46539)
                     /locus_tag="VIB18_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8765585.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLEIYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            complement(46934..48379)
                     /locus_tag="VIB18_000557"
     CDS             complement(46934..48379)
                     /locus_tag="VIB18_000557"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEQ8765586.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            complement(48561..49271)
                     /locus_tag="VIB18_000558"
     CDS             complement(48561..49271)
                     /locus_tag="VIB18_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEQ8765587.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            complement(49402..49899)
                     /locus_tag="VIB18_000559"
     CDS             complement(49402..49899)
                     /locus_tag="VIB18_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEQ8765588.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVRKDMAKLRASSLIPDDVVINGAVYDVDTGKM
                     TQVME"
     gene            complement(50088..51449)
                     /gene="radA"
                     /locus_tag="VIB18_000560"
     CDS             complement(50088..51449)
                     /gene="radA"
                     /locus_tag="VIB18_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEQ8765589.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            complement(51530..51976)
                     /locus_tag="VIB18_000561"
     CDS             complement(51530..51976)
                     /locus_tag="VIB18_000561"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEQ8765590.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            complement(52086..52853)
                     /locus_tag="VIB18_000562"
     CDS             complement(52086..52853)
                     /locus_tag="VIB18_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEQ8765591.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            complement(52971..54755)
                     /locus_tag="VIB18_000563"
     CDS             complement(52971..54755)
                     /locus_tag="VIB18_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765592.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNITLY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVVNIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTVTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            complement(54758..56464)
                     /locus_tag="VIB18_000564"
     CDS             complement(54758..56464)
                     /locus_tag="VIB18_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765593.1"
                     /translation="MLKEAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIESGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIEAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            complement(56457..56906)
                     /locus_tag="VIB18_000565"
     CDS             complement(56457..56906)
                     /locus_tag="VIB18_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8765594.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            57204..58220
                     /locus_tag="VIB18_000566"
     CDS             57204..58220
                     /locus_tag="VIB18_000566"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8765595.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            58253..59152
                     /gene="galU"
                     /locus_tag="VIB18_000567"
     CDS             58253..59152
                     /gene="galU"
                     /locus_tag="VIB18_000567"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEQ8765596.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKTYIIQLGKALEKTKP"
     gene            complement(59251..59922)
                     /locus_tag="VIB18_000568"
     CDS             complement(59251..59922)
                     /locus_tag="VIB18_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEQ8765597.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITMKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            60610..62118
                     /locus_tag="VIB18_000569"
     CDS             60610..62118
                     /locus_tag="VIB18_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8765598.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNKLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            complement(62467..63816)
                     /locus_tag="VIB18_000570"
     CDS             complement(62467..63816)
                     /locus_tag="VIB18_000570"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEQ8765599.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTEKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNLLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(64271..>64383)
                     /locus_tag="VIB18_000571"
     CDS             complement(64271..>64383)
                     /locus_tag="VIB18_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8765600.1"
                     /translation="KDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTY"
BASE COUNT        19501 a        13655 c        11640 g        19587 t
ORIGIN      
        1 gaatatttcg tagaattttc tttattttat acatttatct atatgaaagc gttatactcc
       61 tcttttaatg aggtttcaat tagtttaata aagattgtca ttctctcatg gtagcgtttt
      121 attatatcat tactcttgtg aggtaagtca ttaccttaga caaaaatatg gtataattaa
      181 aaaaataata cttgagtaag gataatctat aaatgatcaa acgattaatt tccctagtgg
      241 tcatcgcctt attttttgca gcaagcactg ttagcggtga agagtattcg gtaactgcta
      301 agcatgcgat tgccgttgac cttgaaagtg gcaaagtttt atacgaaaaa gatgctaaag
      361 aagttgtccc agtcgcctca gtcagtaagc tcttgacaac ctatctggtt tacaaagaag
      421 tttctaaggg caagctaaat tgggatagtc ctgtaactat ttctaactac ccttatgaac
      481 tcactacaaa ctatactatt agtaacgttc ctcttgataa gagaaaatat accgttaaag
      541 aacttttaag tgcgttagtt gttaataacg ccaatagccc cgctattgct ttagctgaaa
      601 aaataggcgg aaccgaaccc aaatttgttg acaaaatgaa aaaacaatta agacaatggg
      661 gcatttccga tgcaaaggtc gtcaattcaa ctggcttaac taaccatttt ttaggagcta
      721 atacttatcc taatacagaa ccagatgatg aaaattgttt ttgcgccact gatttagcta
      781 ttattgccag gcatctctta ttagaatttc cagaagtact gaaattatct agcaaatcct
      841 ccactatttt tgatggacaa accatttaca gttataatta catgcttaaa ggcatgcctt
      901 gttatcgaga aggcgtggat ggtctttttg ttggttattc taaaaaagcc ggtgcttctt
      961 ttgtagctac tagtgtcgaa aatcaaatga gggttattac agtagtttta aatgctgatc
     1021 aaagccacga ggatgattta gctatattta aaacaaccaa tcaattgttg cagtaccttt
     1081 taattaattt tcaaaaagtc cagttaattg aaaataataa accagtaaaa acgttatctg
     1141 tcttagacag tcctgaaaaa actgtcaaac ttgtagccca aaatagttta ttttttatca
     1201 aaccaataca tacaaagacc aaaaataccg tccatattac taagaaatca tccacaatga
     1261 tcgcacctct atcaaaggga caagtcttag gtagagcaac ccttcaagac aaacatctta
     1321 ttggacaagg ttatctggat actcctcctt caatcaatct tatccttcaa aaaaacattt
     1381 ctaaaagttt ctttttaaag gtctggtgga accgttttgt gaggtatgtc aatacctctt
     1441 tatagaataa tacaatgctt tttgtatgac attgactgac agagtacttc tgcagtcttt
     1501 ttcattttta tttaagcaaa ctaggctaat cctaacaatt tttcaaaaaa acttcacatt
     1561 gtattagcaa agtgatatac tgaaaatgca ttacatttaa aggagtcgga aattgaccaa
     1621 aagaattata ctaactattt ttacctttat ttgcttttcg atgatgcctc ttgtccacgc
     1681 cgaagatgtc atggatatta caaggcaagc aggctacaca gttagtgagg ttaatcgacc
     1741 aaaatcttct attgtcgttg atgcaaatag ttcagatatt ctttggcaag ataatattga
     1801 tattcctagg gatcctgcta gtatgtctaa aatgtttacg ctttacattt tatttgaaga
     1861 gctcgctaag ggaaaaatta cgatggacac tactattacg gcaactccaa ccgaccaagc
     1921 tatcgctaac atttatgaga ttagcaataa taatatcgtc gctggagtag cttatcctat
     1981 tcgtgatctt attactatga cagctgtgcc ttcatcaaat gcagcaactg ttatgattgc
     2041 caattattta tcaaacaatg atgcttctgc gtttatcgat cgtattaatg ccacagccaa
     2101 acaattaggc atgactaaca ctcatttttc aaacgctagt ggtgcagcag cacaagcttt
     2161 tcaaggttat tataatccta ctaaatatga tttatctgct tcaaatatta cgaccgctcg
     2221 agatttgtcc aagttactct atgccttctt aaaaaaatac cctgaaatta tctcctttac
     2281 aaataaatct gttgtgcaca ctatggtagg aacgccatat gaagaagaat ttcacaccta
     2341 taaccactct cttccagata atcaatttgg tatgaaagga gttgatggat taaaaacagg
     2401 ttctagtccc agcgctgctt ttaacgccat gataactgcc aaaagaggca aaactcgact
     2461 cattactatt gtcatggggg tcggagattg gtcagatcaa aacggggagt tttatagaca
     2521 tcctttcgtc aatgccttga ctgagaaagg gtttaaagat agtaagacct tatccaaaaa
     2581 agcacgccaa aaactcgaaa aattagtgcc acaaaccaaa aaagaaacat catctaaaca
     2641 gcagcacttc aaagccacta aaaagcaatc gtacttggaa agagtcgaag attttataaa
     2701 tcacaaccac actttcttgc ttatttgctt agctatcttt ataattacta tccttttact
     2761 aagcctcgtt gtctttgcaa tgggacgcca ataatgaatt atcaaaaacc tctgtcaaag
     2821 cacagaggtt tttgatatgt tatcttacgt gtttaaggca actaaaaact aaccacttgg
     2881 ggttagtact acaactcata aaatcctatc tcaaagatct ttcagatgga taagagaaaa
     2941 tgcaattaac cgacagaacc ttccatctca taggaaatca atcgattgag ttcgaccgcg
     3001 tattccattg gcaattcttt ggtaaaaggc tccacaaatc ccatgacaat catctctgtg
     3061 gcttcgcttt ctgataagcc acggctcatg agatagtaga gttgttcttc agaaatctta
     3121 gacactttgg cttcatgttc taacgccacc tgtgaattat gaatttcgtt aaatgggatc
     3181 gtatctgatt tagaaatatc gtccatcaaa atagtatcac attcaatatg ggaaacggat
     3241 tttttagatt gcttgttaaa ggtcacttgg ccacgataat ctactttacc accagacttg
     3301 gcaattgatt ttgacacaat tgatgatgat gtatgtggag cattgtgaat cattttagcc
     3361 cctgtatctt ggtgttggcc tgcgttagca aaggcaatag acagcatggt gccacgcgca
     3421 cctggcccat caaggtaaac agaagggtac ttcatggtgg ttttagctcc tagattgcca
     3481 tcaatccatt ccactgttgc atccgtaagg gcgcgtgcac gttttgtcac tagattatac
     3541 acattgtctg accagttttg aatggtggta taacgcatgt atgcaccgtc aagcgcaaag
     3601 atttcaacga tagcagcatg taagctgtta cttgaataag tgggagctgt acatccttca
     3661 acataatgaa cacttgctcc ttcatcaaca ataatcaatg tccgctcaaa ttgaccagta
     3721 ttttcattgt taatgcggaa ataagtttgc aaagggatat ctaccttgac ccctttagga
     3781 acataaataa aggtaccacc agaccaaact gctgaattga gggctgctaa tttgttgtct
     3841 gttggcggaa ccagtttggc aaagtattgt ttgaacaaat caggatattc tttgagggcg
     3901 gaatcggtat ctgtaaagat aatccctagc ttttcaaatt cacccttcat gttatggtaa
     3961 accacttctg actcatactg agctgatgcc ccagcaagat aagcacgttc tgcttctgga
     4021 attccaatac gatcaaaggt ttcttttatt ttttctggaa catcatccca agaacgagct
     4081 ggcttatcag atgctttttg atagtaaatg atatcatcaa agttaatatc tgataagtct
     4141 gctccccagg tttgcatcgg cattttatta aaggtttcca aggattttaa acgaaactcc
     4201 aacatccact caggttcatt tttggcagct gatagttcgc gaaccactgc ctcactcaat
     4261 ccttttcctg tagaataaat gggctctaca tcatcgtgaa atccaaattg gtagtcccct
     4321 aagtcaattg gctttggctc tactttctca tttatatcag acatttttcc cttcctttac
     4381 attttggtcc gtgaggtgct gagcattggc acttcgttta atggcttcct tgagagcatt
     4441 ccaagctagg gtagagcatt tgatacgctg tggaaatttt gcaactcctg ccaacaattc
     4501 tgcttcacct agctcttttt gagcaggatt ttcctgtcct tgtaccatct ctgaaaaaat
     4561 atcagctaac gcgagtgctt cttctttact tttaccaata acagcatctg tcatcatgct
     4621 tgatgaagct gtggaaatgg tacagccgtt gcctgcaaaa gcaatatctt caattttatc
     4681 ttcgtcaaac ttaacggtca aagaaatcac atcaccacaa gtcggattat tcagttgaac
     4741 agcctctacg ccatctagtt gcccatgatg atgtggacgt ttcgaatggt ccgctaccac
     4801 agccatgtat agatggttca gtttagagag tgccattgaa aaactccttt gcttttagaa
     4861 ttgcttcgac tagacggtca caatctgcct tggtgttata gatataaaaa cttgctctaa
     4921 cagttgctgg tacacctaaa taactaagaa gaggttgggc gcagtggtgc cctgctctta
     4981 ctgcaacacc ttcatagtcc aaggctgttg ccaagtcatg aggatgcaaa tcatccagat
     5041 taaaagaaat cagaccagat cttgcactag gctggcttgg tccatatatg gtaagcccct
     5101 caatagcttc taatttcggc aagacatagg ctattagttc tgcttcatgc gcatgtatat
     5161 cagccatgcc tagtctctga aggtaagaaa tggctgcgct tagcccaata gcaccagcta
     5221 tgtgaggtgt tcctgcttca aacttccagg gcaattcttt ccaagtggcc tcttgttcgt
     5281 aaacaaaatc aatcatttct ccgccaaatt caagaggctc cacttgattc aaaagctctt
     5341 ctttgccgta aagaacaccc aaacctgttg gccccaacat cttatgagct gaaaaagcaa
     5401 agaaatcaca atccaagtct tgaacatcaa tagccaaatg tggaaccgac tgggcaccgt
     5461 caacaacaag gtaggctcct ttagcatgtg ccagcttggc aatttcttta atgggattga
     5521 tgcaaccaag aacattggag acatgtacta ggctaacaaa acgtgttttt gtcgtcaatt
     5581 tgtttgccaa atcgtccatg tcaagttggc catcttttaa ataaacatag actaaccttg
     5641 ctcctgtttt ttgacaggct tgttgccaag gaatgatatt ggcatgatgc tccataatcg
     5701 aaatcaacac ctcatcttct ggcgtcaaga cctgctctgc aaaccgagca acccaattca
     5761 aactggttgt tgttcctctg gtaaagagca cttccttgct tgatttagca tgaataaagt
     5821 cagcaacctg ctggcgactg gcctcatatt tgtgcgttgc acgttcagcc aaggtatgaa
     5881 ctcctcggtg gacattagca ttatcttctt gataatagga ttgcaaagcc tcaagaacaa
     5941 gcgccggttt ttgtgtggtg gcggcattat ccaaataaac aaggggttca tcattgactt
     6001 gttgatttaa gatttgaaag tcttgtttga tgtcttttgc gtctagcaat actaacctct
     6061 ttctttttgg cagtaggtct taacgattaa gcaatttctc atctaaaacc ttaataatct
     6121 cttggcggac tgatggaata ggaatttcag cgataaccgc tcctaggaat cctctaataa
     6181 ccaatcgttc tgctgtttct tgatccagtc ctcgactcat caagtaatac atatcttcag
     6241 ggtcaacctg accgatagaa gctgcatgac ctgctgttac ttcattttca tcaattaaga
     6301 ggattggatt ggcatcggct cttgcttggt cagaaagcat caaaacacgg ctttcttgtt
     6361 gagcatcagc tcccttagcg ccttttagaa catgaccaat cccgttaaac gttaaggtgc
     6421 cacgttccaa aatcacacca tgctgtaaaa tatgaccgac cgtacgttga ccatagttgg
     6481 tcacgcgcgt gtcaatacct tgtacctgac gaccacttga ggctgcaaca actttcaaat
     6541 cagcttgtga gccctgacca atcaaatcac tgtcaaaatc agcaatgaca ttgccttcat
     6601 tcatcacagc taaggcccaa tcaatgttgg catccttctc taaacgtcct cgacggctaa
     6661 tataggttgt cactgaagga cctaagcggt cgatagccga gaatttaatc tggctgcctg
     6721 cttgagcaat cacttctaca ctgatattag cgctgatctt ttgagtggca ttgccaatag
     6781 attcaaaacg ctctaaatag gtgaacttac tttcttttcc tgcaatcact agaacatgct
     6841 tgttaaaagg aacgtcactg tcactatctt gtaagaaaat agcttcaata ggagttgtga
     6901 tttccaagtg atcaggaacg tagagcacgg ctgcgctatt aaaataagca gtgtggtagg
     6961 cagctagttt gtcttcatca aaagctaatg cctgaccaaa atgagcttca attacttctg
     7021 ggatttcctc aagcgccgta taaaaatcac tgaaaacaac tcccttgtca attaacgcca
     7081 ttggtaactg ttctaagact gtttgcgtgc ctacctgaac aagctttggg ttatctccaa
     7141 tagctataaa atctggaaca ctagctagac tttcattttc tgttaaggta ccatctccta
     7201 gattccaacg gtgaaattta accctttcga tggttggtaa ctctaattct ggtatggctt
     7261 ctaatgccgc taaacgccgc tcttgcagcc aagcaggctc agcgtgggct tgcgaaaaag
     7321 ccactagttt ttcttttgtc atctgtcaat cctttgtctc tggtttttaa attggctggg
     7381 tatatagaac atcacctagc tttttgtaga aagctaaagt aattgtctcc aaaaacttaa
     7441 ctttcttcct tatactcgat tcccagatcc tgtgcaatac ctgcgtagcc ttctttttca
     7501 agacgagtag ccaaggcagc atcaccagat aagacaatac gaccatccat cataacatga
     7561 actaggtctg gggtaatgta attcaacaaa cgttgatagt gggtgataat catagctcca
     7621 aagtctttcc cacgcatctc attaacccct ttagagacta cttttagggc atcaatatca
     7681 agaccagaat caatttcatc taacaaagca aatttaggct ctaacatgag caattgaaga
     7741 atttcattgc gttttttctc cccaccagaa aaaccttcgt tgaggtaacg ctctgccatc
     7801 tcttctttca tacctaacaa agccattttc tcatcaagtt tggtgataaa atctcgcacg
     7861 gaaatcttat cctcatctgc cttaccggca ttcattgctg cacgcataaa ttcagcgttg
     7921 gtaatccctg gaatttctga agggtattgc atggcgagaa aaagtcccag tctcgcacgc
     7981 tcatcaactt ctagatcgag aatattgacc ccgtcaagca aaatctgccc ttgggtcact
     8041 tcgtagttag gatttcccat aatagctgct gaaagggtag actttcctgt cccatttggc
     8101 cccataatgg cagctacttc cccagtttta agagttaggt taaccccttt caaaatctct
     8161 ttaccttcta ttgaaacatg taaattatta atctcaagaa ttgacatgat acacccctta
     8221 ttttctctgt catctatacc atctcaagaa aagacagtgt catttgcact gcttttttta
     8281 taatggtcac tgcatctatt atagcaaaaa aagccttact cggctttttt agtgtttcaa
     8341 atccttcttt tctttccatt tcagaagcat tgcttgacga taatcactat taccaataaa
     8401 ctttaacaag ttaaacaaag gcgttcgctt ttcaccccag atctccaatc cttcaataaa
     8461 aacttctaaa ccaaataaaa gtccaaggat caagaggacg ccaccaattc gactagaaac
     8521 atttaaaagt aaagaaataa gggaaaaaag catggtaata ccataaacta ctaagacagc
     8581 tcctcgatga gtaaagccca ttgataagag tcgatgatgc aggtgcatct tatccggctc
     8641 gtagaatttt tgacctgata aactacgtcg aataatagcc acgatggtat ccataatggg
     8701 tacaccaaga ataataacag gtgtcaccac agccacagcc gttgaatttt tcaatccttg
     8761 aagagacaaa acccctatca taaagccaat aaagagggct cctgtgtcac ccaaataaat
     8821 catagctgga tggtaattat aaggaaaaaa tcctgcaata gcagaaatca agaccaaaat
     8881 ggttaacgtc aaaaagaaat ccttttgagg taaaaagaaa taagatacaa tagccatggt
     8941 cactaaacta ataatagaga ccccactaac caaaccatcc aaaccgtcaa tcaagttaat
     9001 agcattagtg atggaaacaa tccacaggac tgttaagaat aaggttaaga aaggaccaaa
     9061 aactaacaac ggccctccaa aaggaatttt gaagctatca aatttaaagt cggtaaaagc
     9121 ccagacaatc actgcaccaa ttagaatacc aaacatcttt aatttaggac ttaactcata
     9181 caaatcatct aaaaaaccag taagggtaat tactgtagca ccaatcacga caggtaaaat
     9241 ataactgaag taggtctgac caaaaaacat ggcgccttta gaagcaatcg gaataagtcc
     9301 caaacttgct actaaaaaag acataaaaat agctaatcca ccactggttg gcatcggaac
     9361 cttattgacc cgtctggcat tgggattgtc tactgcaccc acacgaaagg ctaaaaagcg
     9421 aacaagaggg gttaagaata aggacattaa caaagcccct atcagaacaa ggacataatc
     9481 tattgtgaat gaaaacatac tattttatcc caactcaatc ttttgtaatt gctcaacagc
     9541 accatcaagc atcaattgta agccatgctc ttgtaaataa gctcttgttt ttgatccagg
     9601 gtttgcatgc tcaatcaatc tcgcatacat gacattcgca aaataagatg gttgttgctg
     9661 aacatctaat aaaatagtca tatggtagca gttgctcccc ttatataact ctgaagcttc
     9721 tatcgaaaaa tcaatcgttt tagcaaaagc cactgcctct gtaatcgttg aaaaatccaa
     9781 tacataatgg acatagtcta aaagttctga ctcatgatta gttgatggat cagccgcctc
     9841 agactgatta gctagagtgg cttcaacaac atcttccatt atctcttcaa ttttttccaa
     9901 tttttcatga gctttgacat ctcccttttc acgcatggat tgctccaagc tcttgaaaaa
     9961 atcttccgga gtcatttggg acatatcacc aaactctgct aaatcttcaa gattaatatc
    10021 tttatttatc tcagatttgg taacaaaaac atctagacgg tctttgcgtg gagtcactcg
    10081 aaaactaagc ataccactat ctttaaaatt atctggaaga tcgagttcgt ccatcacaga
    10141 atagaaaaac tcttctgttt tttcttgagg aatcaagaaa tctttcaact ccattcctct
    10201 ttcttctaaa tcgtccatac taattgttat ttttagcgtt gtctcgctaa tttgtttcat
    10261 ttccattctc aatacctcgc acgcgtagtc attttattat actagaaatg ctgtaatttc
    10321 gcaatttatg actaactcct cgtctacaaa aggaaattta aaaagcgaca gtccccaagg
    10381 tctgtcgcaa catcctaaac gatatgtaag tttaaaaaac aaatttaaag aagctataaa
    10441 taagtaaaag gcttcctaac acaatacggt atttcccaaa aatggtgaaa tcgtgtttct
    10501 taacataatc tgtcaagaac ctaatcgcca ataaactaac cacaaaagcg gtcaagctag
    10561 ccactaaaag aataaggact tgtgcaaaat caaggtgatg gccatcaagg aaaaatttca
    10621 cagcctttaa tccactatat ccaaacatgg taggaatggc caaaaagaag gtgaaatcag
    10681 cggccactgt tcgactagtt cctaaaataa tagctcctaa gatggtagcc cctgatcgac
    10741 tagtaccagg cacaatactt aagacttgaa aacaaccaat gaagaaagct gttttgtaag
    10801 acattctagc taattcagtg acggcaggtt cttgttgagc atttcgtttt tcaatccaga
    10861 taaaggcaat cccgtagacg attaaagcga tggcaatcgg aaccataaaa taaaaatgtg
    10921 cttcaaacca attatcaaga ggaaccgcta ttaaaataga aggaatacac gcaatcacca
    10981 cttttagcca taattgccag gtaagctgta cttctcttgc tgttttccca ggttgaaagg
    11041 gattgagacg ttcaaaataa atcaacataa cagcgataat cgcccctaat tgaataacga
    11101 tattaaacat ttctataaaa gccttatcct gatttagtcg gataaattcc tgcactaaaa
    11161 tgaggtgacc agtgcttgaa actggtaacc attctgtgat tccctcaatg atgccaaaga
    11221 aaatggcttt tagcaattcg ataattaaca tgttttctcc ttattaacca ctcttattgt
    11281 gattttctga actgtgatta atgccaagca gcttttttaa aaggcaccgc cgccgcctcc
    11341 tccgccaccg ccagagaagc cgccaccacc actaatcccg cctccggaag agactgagaa
    11401 atttgaggaa gttgtagctg aagacaagct agacacaaag gttggtgtcg tagcatacat
    11461 taccattgat aattcacctg gtcgaacagc ttggtaaacc tcaggtaagg caatacgatg
    11521 gactttcaaa tagcgttcca ctttcttagc gtaaccaaat aaggtggcat aaaccaaaac
    11581 acggttccaa acaaccaaac cttcaatagc aacatcctca aatttgtcaa tgtctcgtat
    11641 catgttttta aagctctgcc attgatgtaa ccgaacaccc ccctcaggtg tttcaatacc
    11701 caatttcttg tattgatcta acttcaggct aatgtaaaag ccaaggcaca tcgttagcac
    11761 cattaaagca aggtaaatga gggctaaccc actttcttta atagccaagt aaatcaataa
    11821 accactattt agaataagca acaaacaacc taatccctgg acactattgt tttttcgttt
    11881 ctctgccggg atcatttgac gataagtatc tggtaagttt aactttttga tagtttctag
    11941 gacattgttt gtaatagctg ccgacgcttt tttcatcgcc ttaatcacct gctcagacga
    12001 ttgacggact tcttgctcga gctttttacc tttgtacgtt ttctttaatt gtttaatggt
    12061 atcagcatca taatggtatt gactaaacaa ttgatccacc ggcaatgtca tcttgtttcc
    12121 aaaagccata tctaagaagg cagcttcctc atctgtcaca cgatctaact gactgatttc
    12181 aagataagct ttcccttctt ctttcgttaa taaaagcacc ttttggtcga tcagatccaa
    12241 caaggtagct tgaacaaggg cctcaaaggt cactccttta gggatcaata atttctggct
    12301 ttctgatgct gtaggggata aataggcaaa actctgtcca taaatcgctt gtgtcaacac
    12361 aagaggcgaa agatcttcag ggacttcgta actgtgatct gtatggttag ccaaatgata
    12421 acgattgaat tgtttcttta atcttgtaaa ctgtattaac tgccaaagaa gaaaacctac
    12481 ctctaccaga ggaatgactt tgccaaatag cagctgtaac aaggtccttc gtctggaaat
    12541 cttagtttct aacgctacaa ttttattctt tttactcgtt gaaacatcaa ctggctcttt
    12601 tcccaataat gcttttttat cccaataagc atgcaattcc aattgccctg agacattctt
    12661 ggcattaatc tgatagcgac tgttaccttc ttttaacact tgaggtttct tttggtaata
    12721 tcctctgtga gcccatagat tagaatcctg aatatcagtt ggggtagtga cggtcaaact
    12781 caccttttct aatgttttgt cccaatcact aatcggtgtc caattcagct ctgccacgtc
    12841 ttgataagct gttaaaaggt ggtgcagttg ccagataacc ttgacgtcaa ccttatcacc
    12901 agcttggcca gcattataaa gttttaaacg atagccatct ccaaggtcac taaactcttg
    12961 actaacaggt acctgttgac cattctgata tacctcaact ttaggctttt ggtcaatagc
    13021 aaagcccgct gacaaatgac ctgtccggcc cagcgaaata tactggccgt tataagaagt
    13081 gtcaaattga taggttactt tttgctcaaa ccgagcagta ttttcttttg ataacagtaa
    13141 ctgaccttca tagttggtga tgctatagtc tacatcagct gcttttattc gtatccctaa
    13201 aagactgaag cagagcacaa gcgtcatcaa aatttttttc atggcaacat cctctttctg
    13261 ccctcatttt accatatttt aaggagatga caaaacctaa accaagtcct tcatcttatt
    13321 tttactcatt attttgaata tttttccata tttcaaccta ttcactgata atatattgaa
    13381 ataggatgca aattgctgta aaataggtct gaatactatt tttgaaacag gagacctata
    13441 tgaaaaagct aatccttagc tgtttggtcg ccttggccct tctgtttgga ggaatgagcc
    13501 gggctcaagc aaaccaatat ttaagagtcg gaatggaagc agcctatgct ccttttaact
    13561 ggactcaaga tgacgcttca aacggggctg tccctattga gggaactagc caatacgcca
    13621 acggttacga tgtccaagtc gctaaaaaag tcgctaaagc tatgaacaaa gaactgttag
    13681 tcgttaagac ctcttggacc ggtttaattc cagcattaac ttctggaaaa atcgatatga
    13741 tcgctgctgg tatgagtcct accaaagagc gtagaaacga aattagcttc tcaaacagct
    13801 actacactag ccaacctgtt ctagtcgtaa ctgctaatgg caaatatgct gaggcaaaaa
    13861 gcctcaagga tttttctgga gctaaagtaa ctgcccagca aggcgtttgg catgtcaatc
    13921 tcttaactca actaaaaggt gctaagttac aaacaccaat gggggatttc tctcaaatgc
    13981 gacaagccct tacttcgggt gttatcgatg cctatatttc tgaacggcct gaagccatga
    14041 ctgctgaagc tgctgatagc cgtttgaaaa tgatcactct taaaaaaggg tttgctgttg
    14101 ctgaatcaga tgctgctatc gctgtcggaa tgaaaaaaaa tgacgatcgt atggcaactg
    14161 tcaaccaagt gcttgaagga ttttctcaaa cggatcgtat ggccctgatg gatgatatgg
    14221 ttaccaaaca acccgtggaa aagaaagccg aagatgctaa agcatcattt ctaggccaaa
    14281 tgtgggctat ttttaaaggt aactggaagc aattcttacg tggaactgga atgacccttc
    14341 tgatttccat ggtcggaacc attacaggtc tctttattgg attattaatt ggtattttcc
    14401 gtacagctcc taaagctaag cataaagtag ctgtcttggg acagaaactc tttggttggt
    14461 tactcactat ttatatcgaa atcttccgtg ggacacctat gattgttcaa tctatggtta
    14521 tctactacgg aacagcgcaa gcctttggta tttcgatcga ccgtacccta gcggctattt
    14581 ttatcgtatc tatcaatacg ggcgcctata tgagtgaaat tgttcgcggt ggtattttcg
    14641 ctgtcgacaa aggtcaattc gaagcagcaa ctgctcttgg ctttactcac ggacaaacca
    14701 tgcgtaaaat cgtgctacca caagttgttc gcaacatttt accagcaaca ggtaatgagt
    14761 ttgtcatcaa tatcaaagat acttctgtct tgaatgttat ctctgttgtg gaactttact
    14821 tctcaggtaa taccgtagcc acacaaacct accaatattt ccaaaccttt acgattatcg
    14881 ccactatcta ctttgttctt accttcacgg tgacacgtat tcttcgttat attgaacgcc
    14941 gtttcgatgc cgatacttac accactggag caaaccaaat acagattgcg gaggtctcaa
    15001 atgtctaact caattattga aatcaaaaac ctcaaaaaat cttacggcag caatgaagta
    15061 ctcaaagata tctccctttc tgttaacaag ggagaagtga tttccattat cggttcttct
    15121 ggttctggaa aatcaaccct cctgcgctcg atcaatcttt tggaagagcc aagtgccggt
    15181 caaatcctct ttcatggtga agatgtcctt gctgaacact acaacttgac tcactaccgt
    15241 gaaaaactag gcatggtttt ccaatccttt aacttgtttg aaaacctaaa tgtattggaa
    15301 aatgctatcg tcgctcaaac caccgtcctc aaaagagacc gtgcacaagc cgaacaaatc
    15361 gctaaagaaa acctcaatgc ggttggtatg acagaacaat actggcaagc caaaccaaaa
    15421 caattatcag gggggcaaaa acaacgggtt gccattgcca gagccttatc tgtcaatcca
    15481 gaagccatgc tctttgatga accaacatca gctcttgatc ctgaaatggt tggtgaggtc
    15541 cttaaaacca tgcaagactt ggcaaaatca gggttgacca tgattattgt tacccatgaa
    15601 atggaatttg ctcgtgatgt ttctgaccgt atcatcttca tggataaggg attgattact
    15661 gaagaaggaa gtcctcaaca aattttcgag aatcctacac aagatcgtac caaagaattt
    15721 ttacaacgct tcttaaaata agataaagga tccaactatt tctatgccag ttgggtcttt
    15781 tttcaattca aaaagaattt gtcataaaat actttaccag ttaactattt tatgctatac
    15841 ttatttttgt taacgttaat aatttatatt taggaggata atatggcaga aaaaactgac
    15901 ttatcgtcag cttacagaag actgaaaagt cccaatatta aaaccagaaa acgtgctctg
    15961 aagattattc acgagtacaa acgttacggt aaaaaataag attttacttt ttatctctcc
    16021 aaatttaagt cagacaaaaa aaggctaaga caccccttcc atcttagcct ttttgtatac
    16081 agtttattaa gggaactatt ttaaaatatc ttttatgcta gagtctagaa tagttcaaaa
    16141 cgttaaaatc atacatttaa ggtagtgttt aaagtatacg aaaaagaact cagcataaac
    16201 caagctctct ttcgttataa ctaattattt agcaattttt gcgaagtact caagagtacg
    16261 tacaagttga gcagtgtaag acatttcgtt gtcataccat gatacaactt taaccaattg
    16321 tgatccgtca acttccatta ctttagtttg agttgcgtca aacaatgaac cgtatgatac
    16381 gcctacgata tctgaagaaa cgattggatc ttcagtgtaa ccgaagctat cgtttgaagc
    16441 agctttcata gcagcgttga tttcgtcaac agaaacgttt ttgtcaagag ttacaaccaa
    16501 ctcagttact gatccagttg gaacaggaac acgttgtgca gcaccgtcaa gtttaccgtt
    16561 aagttctggg ataacaagac cgatagcttt agcagcacca gttgagttag gaacgatatt
    16621 tgcagcacca gcgcgtgcac gacgaaggtc accaccacgg tgtggtccgt caaggatcat
    16681 ttggtcacca gtgtaagcgt ggattgtagt cataagacct ttttgaatac cgaatgcatc
    16741 gtgaagagct ttagccatag gagctaaaca gtttgtagta catgaagcac ctgagataac
    16801 tgtttcagta ccgtcaagaa tgtcgtggtt agtgttgaaa acaactgttt taacatcgtt
    16861 tccaccagga gctgtgataa caactttttt agcaccgtta gcatgtaaat gtttttcagc
    16921 tgcttctttt ttagcaaaga aaccagttgc ttcaagaacg atttcaaccc catcagttgc
    16981 ccagtcgatg ttttctggat cacgttcagc agaaactttg atgaagtttc cgtttacttc
    17041 aaatccacct tctttaactt caactgttcc atcaaaacga ccttgagttg tatcgtattt
    17101 caacaagtgt gcaagcatat ttggatctgt aaggtcattg atacgagtta cttcaacacc
    17161 ttcgatgttt tgaatacggc ggaatgcaag acgtccgata cgaccgaaac cgttaatacc
    17221 aactttaact accattagtg atttcctcct tatgaaaatc aaaagaatat tatttagagg
    17281 gaatgctccc tacctattgt gaaaagatta acttacagtc atctgcaaca acccttcaac
    17341 agaactatta tataactatt tcagaaaaaa tgcaaataaa ttagccattt tcataaaggg
    17401 cagcttcttt cttctagcct tcaaaaccca ccaaatatag gaaagggctt tcttttttct
    17461 atgttctatt ctgtaattta tctttttatt gggaaagatt tccaaaactt caaactgtac
    17521 tataacgttc tgttacacta aaaaagaggt taggatagtt atcctcaacc tcttagtggt
    17581 ggttattcac ctttgttttt cttaatgatt tcttcttgaa ctgacttagg aacatcttca
    17641 tagtgatcaa ataccatcat gaatgtacca cgtccttgag tagcagaacg aagaactgtt
    17701 gcataaccga acatttcagc aagtggaaca taagcacgaa cgatttggct gttaccatgt
    17761 gcttccatac catcaacgcg tccacgacga gctgtcacgt gtcccataac gtctccaaga
    17821 ttgtcttctg gagctgtaat cgttacaagc atcatcggct caaggatagc tggttgtgct
    17881 gatttagctg cttctttaag agcaagagat gctgcgatct tgaaggcagt ttcagatgag
    17941 tcgacatcgt ggtatgaacc atcgtaaagt ttagctttaa cgtcaaccat tgggtaacca
    18001 gcaagaacac cgtttgccat agattcgatc aacccttttt caacagctgg gataaattca
    18061 cgaggaacca caccaccaac gatagcattt tcgaattcga aacctttacc ttcttcattt
    18121 ggtgtaaatt caatccaaac atcaccgaat tgacctttac caccagattg gcgtttgaag
    18181 aatccacgag cttgtgtaga agcacggaat gtttcacggt aagatacttg aggagcacca
    18241 acgttagctt caactttgaa ctcacgtttc atacggtcaa caaggacatc aaggtgaagt
    18301 tcacccatac cagcgataac tgtttcacca gtttcaacgt ttgtttcaac acggaatgtt
    18361 ggatcttctt cagcaagttt ttgaagggca acacccatct tgtcttggtc tgctttagat
    18421 tttggctcaa ccatcaactg gataactggt tctggaactt cgattgactc aagaataact
    18481 tttgcttttt catcagtcaa tgagtcacca gttgttgtgt ctttcaaacc aacagcggca
    18541 gcgatgtcac cagcgtaaac tgtttcaatt tcttgacggc tgtttgcgtg catttgaagg
    18601 atacgtccga tacgctcacg tttacctttt gatgtgttca taacgtaaga accgctatta
    18661 agaacacctg agtaaacacg gaagaatgtc aaacgaccta cgaatgggtc agtcatgatc
    18721 ttgaaggcaa gagctgcaaa tggctcttca tcagatgctg gacgttcttc ttcagcatct
    18781 gtatccgggt taacaccttt gattgcaggg atgtcaagtg ggcttggaag gtatgcgata
    18841 accgcatcaa gcatcaattg aacacctttg tttttgaagg cagaaccaca aagtactggg
    18901 aagaattcaa cgttgattgt tgctttacgg ataccagcaa tcaattcgtc gttagtgatt
    18961 tcttcacctt caaggtattt catcatcaag tcttcatcag tttcagcaac tgcttcgatt
    19021 aatttttcac ggtattcttg agcttgttct aagtattctt ctggaatatc ttcttcaaga
    19081 atatctgtac caaggtcgtt ggtatagatt tctgctttca tcttgatcaa gtcaatgata
    19141 ccacggaaat catcttctgc accgattggc aattggattg ggtgtgcatt tgcttgaaga
    19201 cggtcatgaa gggtttgtac tgagtaaagg aagtcagcac cgattttatc cattttgttg
    19261 gcgaaaacga tacgtggaac accgtattca gttgcttgac gccaaactgt ttcagtttga
    19321 ggctcaacac ctgattgtga gtcaagaacg gttacagcac catcaagaac acggagagaa
    19381 cgttgtactt cgatggtgaa gtccacgtgt cctggtgtgt cgatgatgtt aacgcggtga
    19441 ccatcccatt gagctgttgt agcggcagaa gtaatagtga taccacgttc ttgctcttgc
    19501 tccatccagt ccatttgtga tgcgccttcg tgtgtttcac cgattttatg aattttacca
    19561 gtgtagtaaa ggatacgctc tgttgtagtt gttttaccag catcgacgtg agccatgata
    19621 ccgatattac gagtttttgc aagtgaaaat tcgcgagcca tgtgtttctc ctattttttt
    19681 agtttactct ttcattatag cactatttag caaaaacgga taggcaggac ctacccgtta
    19741 tctaaatatt tgttggtaaa gataatacct attgccttta taaggcttgg tatcttattc
    19801 attgaactcg ggctaaacgc tgtgtgaaaa agataaactt tcctagagac aaaggtttct
    19861 tcgtcaaatt tcctattttc actttgcgtt ctatacgcct tcgtatctta ttaattgagt
    19921 tcgagctaca agccactgac aaaaagataa tagttcctag aaactgaagt ttctgcgtca
    19981 atttccctat tttggctagc atttgtttga cgctaaaata tcttatatta ccaacggaag
    20041 tgagcaaagg cacggttagc ttcagccatt ttgtgagtgt cttcacgttt cttaactgat
    20101 gcacctgtgt tgtttgcagc atccatgatt tctttagcaa gacgatcttt catagtgtgt
    20161 tcaccacgag cacgtgatgc gtttaccaac caacgaagtc caagtgttgt acgacgttct
    20221 ggacgaactt caactgggac ttggtagtta gaaccaccga cacggcgtgc gcgtacttca
    20281 agtacaggca tgatgttgtc catagctgtt tcaaatactt caagagcgtc atttcctgtt
    20341 gcttctttga tagcgttgaa agcatcgtaa acgatagtag cagctgtacc acgtttaccg
    20401 tcaagcataa cacggttgat aagacgtgtt acgatttttg agttatataa tggatctggt
    20461 aatacttcgc gtttaggcgc ttgattttta cgactcattt tctcttatcc cccttctatt
    20521 atccttttgg acgtttcgca ccgtatttag aacggccttg tttacggtca gcaacacctg
    20581 cagtatcaag tgcgccacga acgatatggt aacgtacccc tggaaggtct tttacacgtc
    20641 cgccacggat aagaacaacg ctgtgctctt gcaagttgtg tccgatacct gggatgtagg
    20701 cagttacttc gataaggttg ctcaaacgta cacgagcgaa tttacgaagg gctgagttag
    20761 gttttttagg tgtcattgtt ccaacacgag tagcaacgcc acgtttttgt ggggcagcca
    20821 ttttagtttg aacttttttg tgactgttgt aaccaatgtt caaagctggt gaatctgatt
    20881 tttcaatttt agatttacgt ggtttacgta ccaactggtt aattgtaggc atctacattc
    20941 tcctgtgttt ttttattttt ggttgatata gcacttggtg acagcccata tccggtgcac
    21001 tttttgcaac aattgtcagc acgtctctgt acacttttga gagaccaaaa gtaaaaagta
    21061 ccgtctaata taataacaca gacggtactt catgtcaaat agaatttttc ctttgatgca
    21121 attgcttatg acgaatgcat cacttagatt ccttacggaa cctaaatcct gtgaggccga
    21181 cagctgccaa catgacgact cctgctttaa gagctctttg agtactttca tcaacatcag
    21241 aaatgagatt gctcgttgta gaagatcctg agccataaga tgtcttagat gagggctgag
    21301 taatcgaaga tgtgatttta gacacaatgg cattacttgc taccatttca gaggtttggc
    21361 caacaagcgc ttctgctaca agacttgtat tttcagcagc taatcttgct gaagcttcta
    21421 atagttgttt cgtttcttta accatttctt gaacaagcgg agtagtatct atcttactat
    21481 atgatagcgg ttttacgccc ataagaggtg gagctacttg caaatcaggc acagtagcta
    21541 tatcttcgtc taaatggcga tattcctttt cattagctaa ggttttaagc aaagtcaact
    21601 ggtgttctgt ggtagcaata gtagcttcta gactgctttg tttagtttgt aaggctgcta
    21661 aagtttcttg tgcatttaac aaagatgagg tagttttagc caaatcttgc ttagtattat
    21721 caatgcgctc acgtatcact tgaaggcgat taggattcaa tttaaagtcc cttagatatt
    21781 gcaaatgagc ttttttagcc accagtgctg tcactctggc tgcggcttgc tctgctaagg
    21841 cttctgtctg gtgcagtgcg gctttcaacg atgctagctt agccaatgat tgatcacgag
    21901 tagcttcgag ttgtgcttgt tttgctttag ctgctagtaa ttctgttctc aaagaacctt
    21961 tagtatcatt taattgtctc acttggaggt ttaagctgtc tgactgctta agtgtgcttg
    22021 ctaatttacc ttgaagttga cttactttag cttgggctgc cataatatca gcttcttgat
    22081 gaatagccga caaacgattt tctaatgagc ttacttttcc tttgatcgct gcaatagtat
    22141 cagatacagt gcctactctt tgggcataat cttttgtact tccaacggct tttatagggg
    22201 tcttattaaa gcgttgatgg ttagcaatgt tagactctgg aaacattaca aagtgttcat
    22261 tcaaagatcc tacattgctg gttgaaaatc caaggtaaac aggcgcatta gggttacgtt
    22321 tatctacacg taaaaagtta atagcatggc cgtatgtatt tccgtgtaaa tgatctgtaa
    22381 agagcatata cttgatactg tcataaatac cacgtttaat accattcaca gtatgcacat
    22441 cattaaaagc accgatattc tcgtacatgt tatcatcatt tcgaatgagc cctgacgctc
    22501 cggcagagtc ttcaataata gttttatcat gaggcccaac accataatgc cctgataccc
    22561 ctggctgtcc gtagacaaat gatggtcttg tattaccatg agttttctta tagctggtac
    22621 taagtaatct tgcaaattct tgtgatcctg ctgtaacagt aactggtggt agacctaatt
    22681 gtcttcttac actattaatc atgtgagctg caaactgcgc tagctcattt tgcacttctg
    22741 gtgtcaaatt atcgggatca acaaagcgat tacgatctgc tggaatatct tggtattgat
    22801 ttaattgatt acctggacta gctttggcaa taatttgatc tgcatgctct ttgtaataat
    22861 tattgtaact agctgatcca atataaccac tagcttctaa ttttttaagt tcttcaagag
    22921 gatagccttg cggtgctttc atggtattat tacccacaat gctatcttga gtagacggag
    22981 ctgaggattt aagacgacta agttctgcct ctttttctgc tagagcagct ttctgagctg
    23041 ccaactcttc agtcaattgc tttttaactt tagctttttg attttctaag tcagctttag
    23101 ccttctccaa ttctgagctt aatgcttttg tattatcatt agccgtttga gctgctttag
    23161 tgatagcatc aggattgcta atcatagcat tgagcttagc aatattttgt tcagacgttt
    23221 tgacttgttc cactaaatct tgagctcgag tagtttctgc tgaaatgcta gctttttgtt
    23281 ctgacaatgc agtctctttt gaatgttgat ctgcttgagc attatgaagc tctgtttcag
    23341 tagctgttaa ctctctttga tgttcggctc cttgggctaa tagcgtctcc tcactacttg
    23401 caagagtatt agtgtaaatt tcttgtgcag aggttaaagc tttttgttca ttatcttgct
    23461 gctcttttaa gttgttgatt tcagcagtag tttttgtcag agcggtagca agctctgtca
    23521 gttctgcttt ttgttgactg agagtttttt caactgcatc aatagttgcc tttgcctctt
    23581 gaattgtttc tggttttggt aaactatcgt cgtgagtatt actcgccttc gtttctcctg
    23641 aggctctatc atctgctttg acttggtgag atacgcctac actggcactc aataaagcaa
    23701 ttgttgaggt taaagcaatt ttctgcttaa cttggtttgg cttcgtttgt tctaagtcca
    23761 ttctctctcc tttttccatt tatcgaaaat attaccaact tctacaacaa cattgttgtt
    23821 tttgacatca atctctgaaa ctttcagcaa tgatttgaag gtcatttgct cacgctctga
    23881 ttgagcgttt tctgcaaaca cagcaacacc aactaaagtg ctgtcaaatt ctgtcaagag
    23941 actgatcatt cctgtaatcg tccccccgcc cttcaagaaa tcatctacaa tcaatacacg
    24001 actattgggt ttcaaactac gctttgacag aaacatcttt tcaatacgat cactagaagc
    24061 actcgcataa ttgacagaca ctgtcgatcc ttctgttatt tttaaatcac gtctaacaat
    24121 gacaaaagga acacttaaaa tattagccac tgcatttgct aaaggaactc ctttggttgc
    24181 aactgtcatc acagcgtcaa tcttttctcc tttaaaggca ttggcaataa tacgaccaat
    24241 attttgtaaa attttaggtg tactcagcaa gtctgacaaa tagatatagc ctccaggtaa
    24301 gatgcgatca ctctctgata acctttgaca caggtcttca acgatggtac gcgcttctgt
    24361 ttctgaaata ctgggggtaa aaattacgcc tccacttgct cctgtaagtg tatcgatatc
    24421 accaatgttg gcttcttcaa aagctttctt gataatagcg atatcttctg agatagaaga
    24481 ttttgcggcc tcatatttag ttgcaaaggt gtttaaacta gttaatttat acggattgtt
    24541 aatcaaataa tttgaaatga caaccatacg ttcacttcgt cttaatttca tagtttcccc
    24601 atttttatgt actttttgct attataccat aaagttaata aaaaacgaac attcgattag
    24661 gaaaatattg gttttttgtt cttattaata tcatgcaaga attcaatcta agataaacta
    24721 atcaacattc ctactgaaag gacattctac ttaataacca caacaagagc caaaaacact
    24781 tatgaaacca tcataagtgt taagcacatc aaaaatcatc acaaaagcaa agtaactatt
    24841 acttgagaaa cactgatcaa tagtttggct tgtaaaaaga ccgattatcc atggcaaaaa
    24901 tacgattggt catctcgccc tcactaacac ggctaagagc tgttgtcatc atcatcatat
    24961 tagcatcaat attgtcaatc atatgaataa tttcagcttc catgatgcgt ggacgtaccg
    25021 gactaccgta ttctaattgc ccgtgatggc ttaaaatcac gtgcctaagg acaatgactt
    25081 cttctttggt atcatcgatt tgtagttctg aaattacttt tgtaatttct tcgttaatga
    25141 gagaaatatg cccaatcaag ttaccacgaa cggtgtattc tgtattatct ggtcctgtta
    25201 attctatgac tttagctaag tcatgtaaca taatacctgc aaacagtaga ctcttattta
    25261 agtcagggta gatatctcca atgctatctg ctagtctgac catcgtagca gtatggtagg
    25321 cgaggcctga ctcaaaagca tggtggtttg ttttagctgc aggataagta taaaattctt
    25381 tatcatactt acgataaaga gcccttacaa ttcgttgcca cgttgcattt tcaattttaa
    25441 agagcatctg ttccaaatag tcacgtactt cttcaacact gacaggtgcc ttttctttga
    25501 agtcctttgg atcattgggc tcccctgggc gaacatttcg caaggtgatt tgattaacct
    25561 gaggggtacc attatagacc tcgcgtcgcc ctttcataaa cacgacttta ccagcggtaa
    25621 attcttcaac gttataaggt tgggcatccc acagatttcc tgaaatctcg ccagtgtcat
    25681 cctgaaaggt aaggctaata aaatctttac cagcccttgt cttacgaacc tctgccgact
    25741 taatgaggta gaacccttca aaaagctggt cttttttcat ttgattaatt ttcattattt
    25801 tcctcttcta ataagggcat gttcaagaga gattttgttg cttggtcttg ataagtttca
    25861 acggtattca aggctcgaac aatggcattt gtccttgttg aaatgagctg atccagcgta
    25921 ttattagctg tattcatttg cttttgagcc ttggcaagca ggccgccaaa tttatcgaat
    25981 tctaacttga cattgcccaa aattttactg atgtcatcag catttttttg gatattaagg
    26041 gtcttgaaac caacagataa ggaattgagc aaagcagaca gggtcgaagg acctgcaacc
    26101 acaatatttt cttcccgacg aaggctatca aagaaagccg catttctgac cacttctgaa
    26161 taaagacctt ctgttggtaa gaacataact ccgaaattgg tcgtctctgg ggggttcaag
    26221 tactttttat gaatgtcttt ggcaaagcgt ttgatagctg ccagaagtgc ttttcggcta
    26281 gcctcgatgg ccagtttatc accaacttcg taagcatctt ctaatcggta ataatcttca
    26341 agagggaatt ttgagtcaat cggtaggtaa atatagccgc cttgaccatt tcctgggagc
    26401 ttaatcgcat attctacgcg ttcactagaa ccactaaccg ttacaaattc tctttcgtac
    26461 tggcttgatg tcatgatatc ctcaatgatt tggcctagtt gaagttcgcc taaaatgcct
    26521 cgtgttttgg tattggacaa aaccttattt aaagtaccca catcttgagc cacgctacgc
    26581 atttctccca agcctttatt gacactttct agttgcttgg atacagaatc gaaagaggcg
    26641 ttcagacgat tttttaaggt ttcctccaat ttttcttcaa cgatctggcg catttcctcc
    26701 aaacgttttt cgttagattc ttgcatattt ttgagcgatt ggttgacctg ctggttaatt
    26761 tcttctaagc gtttgtcaga ccggtctcta ctatcagaca aactacggtg caagacgtca
    26821 cgaatatctg ttaattgttg gtaaaggtct gcttgttgtc ggttcatcag ctgtgttagc
    26881 tctaacaatt gttgtttgtt agctgtatcc aactggtagg tcatttggtc agacaaatta
    26941 tccgcgttgc cttctagggt ttgggcaagc tgatgttgaa ggccgttgac tttgaacaac
    27001 agataagccc ctaaacctaa gagaaccaag accaaaagga acaagataag gtccatacta
    27061 actccaatct ttactttgaa taataatcaa gtagccactt ggcaaactaa ctgtaatagg
    27121 ttgatggata aaggcattac tggaatagat tttctttttg aaaaaattat cttgcgtcaa
    27181 ctcaaattta gcaccagtaa tggtcaagtc agcttctcct tctgccataa atgccacata
    27241 ggtcatccct tcttcttgat ggataaggtg ctgacctgcc gggcggtagg taatcatatt
    27301 ttgttggtca cgcaaggcga tttgtgccat aaagggagca ataccagggt cgctaggcaa
    27361 gaaaatattg gataagaggt ggtccattcg acccccaaaa gccccaaaaa tggtcacttc
    27421 cgcctcagga aaacgagcaa agacctcttt aagggctaat tccgtatccg tatcattttt
    27481 ttctggatga gcagtaataa aaagctctgc cttctctttt atatccgtaa acgctttttg
    27541 ggaaaccgaa tcaaaatcac caacagccat attcaaagga agcccatttt ctaataaaaa
    27601 taggctccct ctatcaatac cgacaaaata atcaaaatca cggctgatat aagagagatt
    27661 tcctcccgca aaaagagcaa ctttagacat tcaaggccgt ccttaaggtt tggacttggc
    27721 tcactaggtc actggccttg aaaaggtaag aacctgccac aaagacattg gcccctgctt
    27781 cataacaagc acgaatggtc ttattgtcta ctccgccatc aacctcaatg tcaaaggaca
    27841 atcctttttc atctcgccat ttggctacgg tagccacttt ttctaaacat tctgggataa
    27901 aggcctgacc cccaaaacct gggttgactg tcataatgag gacttggtca actaagtcta
    27961 gcaaaggttc tagggctgtt gcaggagttc ctggattaat cactacccct gctttcatgc
    28021 cagctgcctt gattttttga agggctccat gaatatgacg agtactttct gtgtgaatgg
    28081 tcatgatatc agcaccagct tgagcaaaag cctcaacata gcgttcagga tcaaccacca
    28141 ttaaatgaca atcaaagacc aatttactgt gctttctcat acttgccaca acatctgcac
    28201 caaaactgat gttaggaaca aattgaccat ccataatgtc aatgtgaacg tattcggcat
    28261 ctgtttcttc aatacgagct agctcagaag caaaattagc gtaatcagct gctagaatag
    28321 atggggcaat ttttagagtt gacatggagt agacctactt tcttttgata acttttttat
    28381 atgtttcacg acggttttca atttcactga gaaattgtag gtaatgctca taacgaactg
    28441 gccacaactc tcccgtttca agcgctgcct tgacagcaca cttgggttcg tgggtatggg
    28501 tacaggatct aaacttacac tcatggctca gccggcgcag ctctggaaaa gcctcgttca
    28561 aatcttcagc attagcaata tcatagtcta atgatgagaa acctggcgta tccgcgattt
    28621 ttccgccatg ggtattgtaa aaactcacag ctcgggtggt gtggcgacca cgccctagac
    28681 tatctgagat ttctcctgtt tcaagagcca attcgggggc gattcggttg agaagggttg
    28741 atttcccaac acctgtttgt cccataaaga tggtaatttt atcagctagc aaaggcaaca
    28801 attcctcaag actggtcaca aaatcgtaac cgattgcctg atactgtcga ccaatagcct
    28861 taatctcctc gggactatct aataagtcca tcttagagat ataaaccact ggatgaatgg
    28921 ctttgtgttc aagcaagatg agaaagcggt ctagaagatt gctgttaaat tctggttctt
    28981 tagcagacat aataaccact gcttggtcaa tattgacgat aggaggtctt accaaactgt
    29041 ttttacgagg atgaatcgct aaaatataac cttcagagtt gtcctctgct gagaaatcca
    29101 cgatatctcc aacataaggt gtctcaccgc gcttcctaaa attaccacgc gctcgcgtct
    29161 gatatacctg tccttctgac tccacgtaat aaaaaccagc cagagattta atgattttac
    29221 cttgcaactg tgctcctttg ccctactata ataactctat tatatcagaa aaccgctccc
    29281 aaatcagcat ttgactctaa gtttcactcg ctttaaaaac tgtcaagatt ctctagacca
    29341 ctggctatca tttaggtcac tgctttttaa aaatagaata ttttatcaac taaaaatcag
    29401 atcactgatg atttttgagg taggaaacga tatgaatttt aagaagacct ttgctattta
    29461 cgaaaaagag tctaaccgta ccgctatagt cacgctcttg ttaattgccc cttttttttc
    29521 ggggtattaa aaaaactagc tctgcactgc gataccttaa cggccagctt caataagaaa
    29581 aatccccctg aactgaacat ttctgttttg tctacaaggg aattttttta ttgtcaccgg
    29641 gggaaagctt ttataatcca acttctttta aagcatcagc taatttgcca aaatcttgaa
    29701 tcgacaaggc ctcaccacga atagaaggct tgatatctgc tagtgccaga cctttttcaa
    29761 gtttagtctt gatgtcttca gacttcccaa aatggctagt caagttattc cacagggtct
    29821 tgcgacgatg gacaaagcta aggcgagata ctctgaaaaa gaaatcttcg tcctcaacct
    29881 caatcaaagg ctggtcgcga cgcaccattt tgaggatagc actatcgacg tttggcgcag
    29941 gtacaaagac ggtgcgcggc acaatgaagg caaccttggc agtcatgtaa tactgcaccg
    30001 caatggacaa ggaaccataa gctttagtgt ttggctcagc cgagatacga tctgccactt
    30061 cacgctgcat catgaccaca aactcttgga atggaatctt gctctcaatc aagtgcatga
    30121 gaataggcgt tgtgatgtag taaggcaggt tagccaccac cttgatgggc aaatcaggat
    30181 ttttaaactg cttgatttgg gtctgcaaat cagcttttaa aatatcttga ttgaccactt
    30241 gcacattatc aaaatcgcgc aaggtatctg ccaaaatcgg caccaagcgg tcatcaatct
    30301 caaaagccat cacttcagca gcattttctg ccaaaaattc cgtcaaagcc ccaattccag
    30361 gaccaatctc gataacattg acattctgat caatctcagc cgtgtcaacg attttctgta
    30421 aaatattggt atcggtcaaa aagttctgac caaaagattt cttaaaggta aatccgtgac
    30481 gatcaaggac agccttggtc acgctataat ctgcaattct catatattct cttcttttta
    30541 tgatcacttt ctttttggca tttgaaccac tagcctaaac ttttttgcca agacacgcca
    30601 ttcagttaat ggggctgtta tattttattg tactctttac tcctcatatg tctccatcac
    30661 ttcttccact tctgctaggg taatgccaaa taattcgagg cgcttgagca gttgtttgcc
    30721 gttggcataa ccgatgcgga gcttttcacc caagtattcc ctgcgtttac ggctatctga
    30781 cgccattaaa agccctaggc gaatcaggtc tgtttgacga atgtcaaaat aagactcatc
    30841 atcatattgc tgagtgacat gagcaagtgc cttttggagg tcctcaaatc tggcatgttc
    30901 aacccctaag gaacggccct tactcttaga actcggaacc gcctcgtttc ggtttaaaaa
    30961 ggcatgacga gctgttggca cagcagccat aatgagctta cgaatgcgct caccattata
    31021 atctgggtct gttaaaacga taacaccacg caaatcgttt aggcgattga ttcgttctaa
    31081 atcttcttca gtgatagcgg agcctctggt ctcgtaggtg tccacattgt aaaaacggcg
    31141 taggttagcc gtgtcgtcct tgccttctac aacaagaacc tcttgaatat taattttttc
    31201 agtcaagctt gaataccctc tttgcattag cagtcgttgc ttttgcaact tcttccacgg
    31261 tcattccccg tagctctgcg attttatcaa ccacatagcg ggtataagct gtatgatttt
    31321 gtttgccacg ttttggaact ggtgtaagat aaggggcatc tgtttccacc aaaatcttat
    31381 ccaaaggcaa gtgctgcgct gcctcttgaa tatcaagagc ctttttgaaa gtgaccacac
    31441 ctgaaaagga aatcatcatg ccaagttcaa tgaaacgttc agccatctct aatgaccctg
    31501 agtaagaatg catgatgcct ccacgagggc caacaccagc tgctttgatg acctcatagg
    31561 tatcttccaa ggcatcgcgg gtgtgcacca caaaaggcaa atcatggtct tttgctaatt
    31621 gcatttggcg cttaaaaacc tctatttgca cctctttggg gtcctccatc caataatagt
    31681 ctaagccaat ttcacctaag gcaatcactt tgggatgtga taattgagag acgatagcct
    31741 cctcaacagc ctctgaataa gaacctgctt ctgttggatg ccacccaata gttgcataaa
    31801 tattggcata tttattggct agagttagtg ccccactaat agtggcctgg tcaaagccaa
    31861 ccacattatg gtaggccacg cccatttctt gagccaaagt caattcttca gtttcgtgtc
    31921 cttgaaattc tgctacattc aggtgcgtat gggtatcaaa aatagttagt ttttctactt
    31981 tatttgtcat gatgttatta taacataaag atcttaacca catcagaaaa cttggtgaga
    32041 acttctgccg tttaggttga tcgtaaaacc ctttgctagc tgacacttgt ctattttcta
    32101 cttttttgac aaatgacctt taatagtcgg ctcctacata agccctcaaa aatactacaa
    32161 cctactcaaa taaagtgggt tgaacaaatc tgtatcacaa aaagggtcgc taccttctgt
    32221 tagcgatcta tgctatacta gtaggtagtt aaactgtaag gagtgtgctt tgctatgcct
    32281 aaaaaccacc gcctaattac taaaatcgaa gcatcattgg aacatatgac cagtttagaa
    32341 aaagggattg ctcatttttt tattacaacc gatctgacac ctcaagagtt aaccgcatcc
    32401 gagatagtta agcgactaca catctctcaa gccgccttga ctcgatttgc aaaaaagtgt
    32461 ggttttactg gttatcgtgc ttttgccttt gattaccttc acagtcttca agaatcacaa
    32521 gagactttcc aatctattca cttagaattg acaaagcgcg tgctgatgga ctacgatgct
    32581 cttattaata aaacctatga gctcgttaat gaggaaaaat tactgaactt agccaagctg
    32641 atcgattctt ctgagcgagt ctatttcttt ggcaaaggat cttctggact agtagcaaga
    32701 gaaatgaagc tacgctttat gcgacttggt ttaatctgtg atgcttattc agacactgat
    32761 ggctttactt gggcaaatag cctcgtcaat gataattgcc ttgtttttgg tttttcttta
    32821 tctggcaaaa caaactctgt catcacagca cttcatcaag ctagtcagcg aggggccaaa
    32881 actgtcctct taacaacaga taatcaaacc gaatttgacg actccttaga tattattccc
    32941 gtatcatcaa cccaccaact acattatggg aatcgtgtgt caccacaatt tcctcttctt
    33001 attatgatgg acattattta tgcttacgtt ttagcgattg acaaaccgca caaagaaaaa
    33061 atcttcaaaa acactattat tgacaaagaa aataacgacc tttagactac aatagcaaaa
    33121 agggcgttgt tttcttttta aagggtcgtc attcacctcc cccagtatac ttaaacaaga
    33181 actcttcacg tcatatagac tcacagccac taagattagc tactcgctaa attattttcg
    33241 attttctcaa gagttataaa tgaacaagat cgctcattct tttgtttaaa atggtagtaa
    33301 gctcctaata taccagcatt atttccatga ctagcaaact tcagctgagt tttcttggca
    33361 agactagaaa ccaagtagct atcaagagct gtctttaatt tatcagctaa atagtctttt
    33421 tgcgccatga taccgccacc aagcaccacc acatttgggt taacaacgta gcagatatta
    33481 gcaatacctt gtcctaagta atccacctgc ttactaatgg ctgctataca aatcgcatca
    33541 cccgctttag cctgctcaaa aatacgacga ccatcccatt ggctaatgtc atcgccataa
    33601 gctaaggcca cctcttgaac aagagctgtg gtagatgcca gatcctgaaa ctgaccatct
    33661 gacaaatgaa ggtaaccaac ttcgcaagct gaatgactac taccatgaaa aacttgggaa
    33721 ttaaacaata aacagccacc gattcccgtc ccaattgtca agcaaagagc cacaggataa
    33781 tccttggcac taccagaaat agcttcggct agaccagcac agttaacatc gttttccact
    33841 tcacacggta acccgaaagt ctcttcaatc tcttttttaa actgagttcc agcatagtta
    33901 ggaatctgag ggccggcata aaagatttct ccctcatcag gattaaccat tcctgcagaa
    33961 gaaatggcca ctccagccag atccatttgg tcttgatagg tctttaccaa gcccttgacc
    34021 ttttccaaaa tagagggacc acctttataa gcctcagtgg ccatttcctc tttttccaac
    34081 aggtctcctg tttcagaaat caagccatac ttgatagcag taccaccaat atcaattgct
    34141 aaataatgct tcatttgtta tcccctcgca tcttatcaaa aggtttcctt agcctgatta
    34201 atcagagcag cagcccgttg gcaaataacc ctatcttcct cgaccaactc agctaaaggt
    34261 gatcgaacag aaccaatatc aagaccctca ttaatacgaa gtacttcttt aataacccca
    34321 tacatattgc cgtgagcaga aacaaggaca ccgataatct cattaatagt atattgaagg
    34381 gccttggcct tttctaaatc cttgtcagct ataagttgat tcagccttaa aaataattct
    34441 ggcatagccc cgtaggtgcc accaatgcct gcagcagcac ccatcaagcg ccctcctaga
    34501 aattgttcat ctgggccatt aaaaacaata tgatcgtccc caccaatcgc acagaaggtt
    34561 tgaatatcct gcactggcat ggatgaattt ttaacgccaa tcacgcgctt attagccaac
    34621 atagtcttat aaaggcttgg ggtcaaggca acccctgcca gttgaggaat attatagatg
    34681 ataaaatctg tgtaaggagc agctgaagaa atcgcattcc aataatcagc aactgcatat
    34741 tctggtaacc ggaaataaat aggcggaata gctgcaatgg catccacgcc caaacgttct
    34801 gaatgagctg ccaattcaat actatcttta gtgttgttgc aggcaacgtg attaataatc
    34861 gtcagcttgc ccttagcgac tgccatgaca ttttctaaca ccaattgacg gtcaaaaacg
    34921 ctctggtaaa tacattctcc agaagagcca ttgatgtaaa gcccctgaac ccctttgtca
    34981 atatagtact gggtcaaggc acgcacacgc tcagggctga tattcccctg gtcatcgtaa
    35041 caagcgtaaa aggcaggaat aatgccttgg tatttcgtaa gatctgtcat agtaatgtcc
    35101 tttattcaat gtcattatta agtgggaatc gcctaagaag agattccatg ataatcaagt
    35161 agaggtaagt taggctactg atgccgatga tagctagcaa agacacgcct ccaaataacg
    35221 ttaacagaga caattgtagg ctaaatatcg tgagacaaat aaaagccaag aaagcaaaac
    35281 tccatggaaa aaagagtcct gctaataaaa agcttcgctt aaacagcgta gatagggaaa
    35341 ggtctctttt gacggcctga ggataagcgt acaaaaagag tataactacc aaaaataaaa
    35401 cagcaacgca aagtacttta accccttgaa aaactagacc tgattggttt cgaattaaga
    35461 aaagatctaa gagacaaata gtcattatcc caagctcaat aagacctagg cgcatcccac
    35521 ttttaaaata atgtttaaaa tgagagctat aagtagtaac aagctgacta acttgacctt
    35581 ctcgccaatc caacaaactc gcatacaaag ccattttagc aaccccaatc gttagaaggg
    35641 gaaggcagga caagacaaat aagagattaa acacgagcaa atcaaacagt gctgcgctag
    35701 ccctcatcca tttactatca agcttgaaga gagagtgtaa aagtccctgt tttttcgatg
    35761 tcaaatcaca acttcctttc tagaaatacg cttacaaaca aaagctaact ctcctcttaa
    35821 acgcttaaca catgacttgc ttcccttttg acttatctac ctatgcacct aaattaagag
    35881 gcaacctata gattaagctt agtgacacgc tttatttagt ctaacctttc acagcaccca
    35941 tagtaatgcc ttgggtaaat gatttttgga agacaagaaa taccgtcaca ataggcactg
    36001 cagccatggc agcccctgcc ataatcaagc cataattagt agccatttca gcttgcatag
    36061 tggcaacacc aagtgaaatc gttaaatttt cccgagaggt taacatcacc aactgcataa
    36121 aataatcatt ccaagtattg ataaaggtaa aaattgctag cgctgcaaag cctggtttga
    36181 caatagggaa agccacattg aaaaaggtac gaatttcgcc acatccatca atcttggcgg
    36241 attccaataa ctcggttgga atattttctg agaactgttt cataaggaaa acaccaaatg
    36301 gccagcccac aagaggcaaa ataacagccg ccaaagtgtc atggattccc ataaaattaa
    36361 caatccgcac aagaggcact agaacaacct gttttggcaa ggccatagca gcaataaaaa
    36421 tcgaaaacaa aagccgctgt ccataaaacc gctttttggc caaagcatag ccagccaaag
    36481 aggaagtgcc acaaaccaag aacatagtcg ccaccgaaat aaagacactg ttccacaacc
    36541 attttaaggc tggattttga atgaccaagg ccttaaaatt ttcaatagta ggtgcctttg
    36601 gccaccattg cggtggaatc ataatggtat cggcttgagc cttaaatgct cctgtcataa
    36661 tccaataaaa tggaaaaata aacaaaatgg tcaaaacaca tagcatcaca gtggttaaga
    36721 tatctgatgc ggttagtttc tttttcatca tcttaatatc ctcctaatat tccacatcat
    36781 tacctaaaat tttaaattga gcaaagctga tgattgcaat catgactgcc aagaatacac
    36841 ccattgtgtt ggcatagccg tattcagaga gcttaaaggc cttttcatac aaataataca
    36901 tgagggtact ggttgaataa tttggccctc cagacgtcaa aagttgaatc aaagcaaaac
    36961 attggaagga attaatggtt gttatgacag caatatataa ggttgttggc agaagacttg
    37021 gccacttgat attccaaaac acctgaaatt ctgtggcgcc gtccacacgc gcagcttcca
    37081 tcaaagaatt atcaatattt cccatagcag caatatataa aataataggc tgtccaacag
    37141 atgtggttaa taaaataaca ataatagcta acaaagccca gtgcttatct cccagccaac
    37201 taatgttttg ttcaatcaca tgagcatatt ttaagacata attcaaaatc cctgacatcg
    37261 gatcatagat ccatttccaa accaccgtca ctgcaacact tccggtaaca acaggcagaa
    37321 agaaaactgc ccggtaaaac gaacgcgcca ctacattttt gtcgtaggtt ttagccgcca
    37381 caaagaggga aaagaaaact acaacaggta ccgaaccaat aacaataatc aaggtgttaa
    37441 taagagactt catgaaaatg ggatcttgaa acatcctagc ataattagca aaaccaacaa
    37501 aggtaaaatc cgtcatggaa taattgaaaa aactcgtcac aaagcccata atcatcggta
    37561 tcaagacaaa aatcacaaag aaaaccaaga ccggagctaa gaaagcgtat gagatgagcg
    37621 tctctctcat ttttaattta ttgacgttca cttgaaatac ctctttttct attaatctct
    37681 cctaaaaaaa aggaaaggct cctttccagt gaccatttga catgtgccgt gaaaagaagc
    37741 cacttgttct gaacacttat tgtgtttttt tgattgtctt gttcgctttt tcagtgaagg
    37801 ctttcaaagc atcttctggt ttttcatcac cattagagac ggcttgaacc attgggaacc
    37861 aaagagttct catttcagca aacccatcaa tcgtgttgta gtatggtgag tagaattttg
    37921 tccattcagc aattttttcc attcgtttgt ctttgtaaag atccccataa gaagttctta
    37981 cagggaaagc acctgtacga acaacatttt taggtcccca ttctttatca tcagcgataa
    38041 attggataaa tgtcttagag gcagcgactt tttgttcatc tttgttatta aagaccgcaa
    38101 aaccatttac gaggtattct agttctggtt tgccatcatc tgatgggaat gggatttcaa
    38161 ggtaatccac tttactagct tctaacaatt tagcttggat gccgggttgt gcaggcgccc
    38221 aaagaatggt aaaggaagtt tggccattcg caaagttttg aatatcagct gaaccgtcgt
    38281 attgagagcc attcatcatt aaaccatctt taatccaatt ggaaatcttg gtcatggctt
    38341 taatagagtt agcatcatct gtggtgtatt tggttacttt gtcatcggta atatgactac
    38401 tataaaggtt agcaaagaag gcacgtggtc cttggtcacc accttgacca ttagcaaaga
    38461 aagaacctgg gttatatcct ttgtccttca atgctttcaa gactttttca aaatcatctg
    38521 ttgtccaacc ctctttcaca aggtcaagga cgccagcatc tttgagcatt tttttattca
    38581 acgccatgta gaatggagca gagctgatag gatacatgta agctgtatct cctgcttttg
    38641 aggcttgaat caatttgtca ttgttaacat ctttggtaaa ctcttctgtg aacaagtcat
    38701 tcaagtcagc caatttccca tttttaccat attgaatgat acgacctgga gcatcaaaga
    38761 ggacatcagg agctgttcca gcttcaatag cagttgtgat tttctcagga ccagatgtaa
    38821 aatcaatggt ttccaatttt accttgattt ctggattagc tttctcaaag gcagcaatca
    38881 atttcttctc ataggttccc acaccatctt cagctttttc ttgcgtgaag accgggaaag
    38941 cccaccatgt gatttctgtc ttagcagtat cagatttact tgcaccagcc tctttctggc
    39001 tctttccgcc acaagctgct agtcctaaaa cagatgcacc aagcatcgct aatgaagcta
    39061 acttcttcat gttcatcgta aaatctcctt tttttgatgt gtgtttctag tttgacaacc
    39121 actattagga tttgaccgct tcgataaaac gctctgcaat ttccttaggc cttgtgatgg
    39181 cccctccaac aacaatacct gccacaccta agtcattaat tttcttggct tcttctgggg
    39241 aatgaatctt tccttcggca atgacagcaa tgcctgcttt gcaaagagct tctatcaatg
    39301 ccacatcagg acctgcttcc tgacggctat acggggtgta gcctgacaag gtggttccaa
    39361 caaaatcaat gccagcctga tgggccacta gtccttcatc aaaggtacta atatctgcca
    39421 tcaaaagctg attggggtac ttttccttaa cttgtcgaat aaagctagca atatctaagc
    39481 catcatgtcg gtcacgcttg gtacaatcca tagcaattac tgcaatattt aaggcagcta
    39541 attgatccac ttcggccatc gttgccgtaa taaaaggctc ttgcggcggg taatcttttt
    39601 tgatgatacc gataattggt aggtctgtta tggcttgaat ttctttaatg tctctaaccg
    39661 aattagctct gatgccgaca gcaccagctt cttgagcagc ttttgccatc agtggcataa
    39721 tacccccagt ctctgaataa agaggctcac ctggcaaagc ctgacaagaa acgataatcc
    39781 caccctttaa ctgctccatg agcttttctt tgattggttt atcaggcata gtttctactc
    39841 cttgtgtttc ttagttttaa taaaaataac gttcacaaag ttattataac aaaaaataaa
    39901 gcgctttcaa tagcaatgag acttttagaa tctactttca ttttttatat tattttctat
    39961 tatttggaat gctctttcat acaacaaata agaaggtaag gagttgacac catacttata
    40021 cattgcaaat ttccgattag aaaacgttaa aaaaccaaga gcctcgagca ctcttggttt
    40081 actttagttg tattttttgc aattaagctg ataatacttt acgtccttta cgacgacgtg
    40141 cagcaagcac acgacgtccg tttttagttg acatacggtg acggaatccg tgtttacgtt
    40201 gacgacggat tttacttggt tgataagtac gtttcacagt gaatacctcc tcatagattt
    40261 tgtattcgtt tagccggcta tttgtgatat cagttactaa acatactata atattctatc
    40321 ttaaagaggg tctactgtca agatttattt tcgtttttca acagtttctc tctcatttaa
    40381 gaggccgctc atttcataaa gtgtctcttc tttgacatgt tcctttgcct taccgttgaa
    40441 accttatcaa tagcaacaat aatcaatgag atcagtaaaa caaacggtta agctggccat
    40501 acaaaaaatc ttcgatagct aaactaacta ccaaagattc tttttaggat ctaacgttga
    40561 agactgacta ccacatagcg gttagggtca ttgccttcag aataactatc aaccccttca
    40621 atggatgaaa cggttttatg aacgatttta cgctcactgt tactcatggg atccatggtg
    40681 taatcttgac cagattccaa aacgcgtttg gcaacttttt gcgtaaagtc aatcaaggtt
    40741 tctgttcgat gttccacata atcatggaca ttcaaggata ctgaaaaatt ttttgaatag
    40801 cggtcgtgca agaaattttg agctaacaac tgcaaggatt tcaagacctt accatggtaa
    40861 ccaatcacac gtcccgcctc tggcgtttca atctgcaaat tgatttggcg acgattgttg
    40921 ctggtttcaa cggtagcttc gatatccatt tcatagataa ttttagtcac ataatcggac
    40981 acttcctgag cagctttctc aatatctttg ctgaaaccat cattactagc atcttggggc
    41041 acttctgatt cttcgactgg gattgacggt tgttgtgctt ttgtttcagt gactgtctca
    41101 gcaagattag aaggggtttg cgctggacta tcttcagaca tgagaggaac cactttggta
    41161 tcttctgctt ctaacttttg agtggctttt atttcttcag gttctacatc agcagaattg
    41221 accgcgggaa catttttttg attaatatcc tctggaacac ctcgagtggc ttttttatca
    41281 gccttataaa ccgtcttgcc gctgatacct tcgatatcaa cttgggctgg ctttttacca
    41341 aacccgagga aacctttttt ctcttttgaa atgactttga tatgcgcttt aaggcgtgat
    41401 aaccctaact cttgaagtcc tgtttcgata gcttcttcga ctgtttttcc tgtaaataat
    41461 accataacct aaactcctat tttctcttca ttgctttttt acgagcacga cgttcacgaa
    41521 gacggcgttc tttttcttca ttggcaagac gttgtctttc cgcaataatc ttaaaaggat
    41581 tgtttaataa cagtagttgt aacacttgga aggcattgga gaccgtccaa tagagcacta
    41641 ctccactagc caagttaaag cccatgaaaa agatcattag cggcatcaca taaatcataa
    41701 cagtcatcat gacatttttt tctttagccg ctagattggt caaccaagtg gacaagaaag
    41761 tgaagacagc tgccaaaact ggtaaaaggt acaaatgatc atgttgtgcc aattccaccc
    41821 acaagaaagt ccctgttttt aagaaagata cccgtgtcaa ggcttggaat agggcaatca
    41881 taactggcat ctgaattaag aggggtaaga ggctagcata agggttaacc ccatattttt
    41941 tgtaaagggc ttgactttct tcagccaact tcatccgcgt ttgtgtgtct ttaccagcgt
    42001 atttcttttg caattctcta agctcaggtt ggatgtcttg catcttctgg cttgatttga
    42061 tttgcatatt aaacaaaggc atgagcatga gacggatagt aagggtaaaa agaataatgc
    42121 caacaccaat tgaaccatca aaggaaagcc attgaattgc tctggcaaat aagtaaacca
    42181 actggtccca accactagat gattgtgccg ttacctcacc acgaccacag gccactaata
    42241 atagaactaa ggggactatt cttgcaattt taatgttttt cttcactctc aagacctttc
    42301 tcaagcaatt gtgctaactt taaaacatga tgtaaatttt gttgaagctc ttgatactcc
    42361 aaagactcga cacccttacg ggcaatcacc acgaaatcct ctgacttcag ctgatgccct
    42421 aatgccatga taacatgacg tatctttcgt ttgactgcat ttctggtgac tgcatttcct
    42481 atttttttac cgacagaaat acccacacgg aagtggtctt ggcctctatt taaatgataa
    42541 atgacaaatt ttcgatttgc tgtacttttt ccatccttaa atatggcttg gaaatctttc
    42601 tcacgcttga cacgataggt cttcttcaaa atttaactcc aatatctaaa ttattaccat
    42661 tataccacat cccctaaaaa attaaaaagc cctaaccctt tcagattaag cctctttctg
    42721 tactatttct agtttttgtg cttcaactgc ctcttgtcac tccatctttt cgtagtatag
    42781 ttcttctttc gacaaaggaa taaccttcag aaaacaacca taaaaagtca gaatccacaa
    42841 gacgtcagct acttatccct gtatttacct attaaaaaac ccggcaagcc gggctttaat
    42901 actgatttta caaccagcta atgtgatatc caaacaaaga caactgacat cgtcattttg
    42961 tctgccgagc tatcatatca aaaatactat ttgtttatgg agagagagaa aacaatattt
    43021 tgattgaatt ggggattgat tgctcgataa actcatgact tcgtaaatct ttatttacac
    43081 taattattat agcgaaaaat gtttcaataa gagcatcatt tcctgaaatg ttgctttttc
    43141 gtcctaaaat gttattgctc tcttaacttt agcgaagagc ctcccaccgt tcaaacagac
    43201 atttcatttt taatcgtgat accatacaag aatcaccatt ttcgaaataa aggagctgct
    43261 tactcttatc aattcgaaca accttatcta gattcacaag gtaggatcta tggcacaaaa
    43321 aaagtttcgg tgctactgct tgaatctcag atagattacc ataaaactct aatctttctg
    43381 tctgagtcca taaacaaact ttgtgaggag ttgtggctgt agcaaagtat aaaatatcct
    43441 tatagggcaa ttttaatctt gtctgtggag tctcaaataa aaacatgtcc tttgactcac
    43501 gactagacat catatcgtaa gtatatcgga tacattcttc gatttgttct ttaaactgtt
    43561 tttgaccacc tgctttatca ataaaatcta gagcggatac cttatattta aaagaaatag
    43621 gagcaaattc tgaatgagtg gtgacaaaca caataacggc attaggatct ttttgtcgaa
    43681 tagctgcagc taattcaagc ccacaacgag tatattcacc aatttcaata tctaaaaaat
    43741 acagctgatg gtctcctctt tcttggatac tctcaaataa tttttgagga gtcgagaaca
    43801 cttcaagctg attacatggt attctagtct cttttaagat gcctactacg atagattcta
    43861 tgcgtgtctg ctggataaaa tcatcctcaa gaataaaaat gttcatcata ctttatctca
    43921 tttctaacaa ttgtcttaat cgataatggt cacttttagt cgaaagcgtt atttgggggt
    43981 aactatctaa aacagtcaaa aagtgggctg agttctgctg ctgagcatca aagcgtttgg
    44041 ctatatccac acgattggtt tttgtgctat tttcaataat aaataattgc ttgttatctt
    44101 gtttaaagta tgcaatagat aaaaaaggac gtctactgcc tttggctgtc tcaatagcat
    44161 tgtccactag tccagtaaaa agtacaatta agtcgattaa cttaataggt aaatgatcga
    44221 taacatctgg aatctcaata taaagttcaa tacccaaata ctgagcttca agcaatttgg
    44281 aattcatgat actgcgaatc acagcctctt tgatattgtc taaagaagat atttcataat
    44341 ttgtgcgcat catagaagtt gccgattgct gaataaccgt gtcataaact ctagtaatca
    44401 gatctatatc accactatcg atactatctt ttagactaat taaaatattt tcagaatcat
    44461 gtttaactgt tctgatttct cggtaaagtt gctcaatcga ttgattgtaa ttttcaagat
    44521 acgcaatacg ttcattttgt gcttgtgtta atttttgtga cagctgatct ttagcaaatc
    44581 gatctaattt cacaataacc caaataaaaa tagctaaata aataaatact aaaatagacc
    44641 ggtactggaa atatagtgca agaaatccgc tttgcacagt taccaaaaaa tgggcgaaaa
    44701 agtagtaaga aaacatggca gtattcatcc aaaataccca ctttttcatc ttatcttcac
    44761 tgataaacct tattaagctt aagtcaatac tgaaaatgta gctaaacaga taaaatattg
    44821 gtaatacaaa aagataacat aactctaaaa gcttaaggtt attattaatt tgaccaatgc
    44881 taaatcctaa gacagctggt aaaaagaaag atccgatgac gcgaaacagt aattcgacaa
    44941 tcaagatagt aaagaaacca ttaaacatat gctcaaataa tttctttttc ggagcactta
    45001 acaaactaac aataataaag aacagttggt caatcaaaat gactttgtca aatatcatat
    45061 tagcaattac aaaactaatg cctataatgc taacccgttt ccagcttagt ttaatagcag
    45121 aaacctttgc aaaaatgacc cagctgttaa taaagatggt agcatagaat aaagccatac
    45181 tgtatataac catcatctat ccacctcctc ctttggcatg gtcaaggttt ggctaaattc
    45241 cttatcaaaa cttttagtcc gcaaggataa ataaggatac tttttgagaa tacgctgcgc
    45301 attagaaagg ccgataccac gttctgaacc ttttgaagaa tagccttctt caaagatctt
    45361 gttaatgtct accttttttt tagtcgtatt tgtcacaaca aacatctgat agtcatctaa
    45421 caaaaagtaa gcaattgaca tatgaggttg ctgtgcttca agagctgcct caatggcgtt
    45481 atcacaaaaa atagacatca acaatagtaa gtccaactca ggaatgtaag tctcttttat
    45541 attatctggc acttccacat tcaaatcaat acctgatttt tccgcactga taattttagc
    45601 tgacaataag ctcttaatcg atgagatatt aattttccta agcttcgaga tattatagtg
    45661 tttatcatcc cagtagtcgt tagcttcatg aaccgtttgg gcataaatat cttgaatctg
    45721 agtaatggat tcactcttaa tggcttgacc taaacgctct atacggctca ggtaatcact
    45781 ttgaaaagct cttacatctc gatagagttt ctcaagatgt ttcccataaa tctctaagtt
    45841 agtcatataa gcttgttgtt ctcttctcaa ctcattttta aggtattctt tagaactatg
    45901 attaaaataa gatagaagat aaactaaaag aagtataaac atcaaaaaca ataacttata
    45961 aggtgtggga acaaaaagag aatgatgaaa atgtaaaaag gggtccgtaa atcctaaaat
    46021 gacaaaaatg tccacataat aaaccaaaac aaaaatcagc aatgtttgat agaaattatg
    46081 cgatcttttc gaatatccgg attggcatat catcttgtaa tcttttccaa tcatataatt
    46141 aataatagca aaacttggaa aaatcagcag ataagcaagc aagtcaaaga taatatgacc
    46201 cagataaata ccactcgaca aaaaaagata ggggataacg attgtaccca taaatcgaga
    46261 tagcaaatcc accaaaacac taggtgcaac agccaaaaaa agagctttca aagaaaataa
    46321 ttgcttggtt tcttgcctta aaacaactaa aaataataga ggatcaatta gcaatggcga
    46381 caaatacggg aactgattga aaaatagggc taaagccaaa atcgttagtt gtttccaaac
    46441 tggtaatgtg atatcagata gaaaggaaaa aatataaatt tttgtcatat aatagacaat
    46501 aattgataat aataaaaaca tatattcgct attagccatt tttttctcct ttccaacttt
    46561 attattttag catattttat gacaatgatt acaatattat ttgattacaa ttgattagct
    46621 aagtgagtac taaactagtc tctttcagta tataccaaaa aaatattgta cactaattga
    46681 ttcataaaaa ccatttcttt aaatcacact aatcaaaacc tcaccgtttg ctgtcattat
    46741 cacgtaagca tctcaccacc tctctttcaa atccaatctc caaaatagaa ataaactata
    46801 ctatttttta ctttaccaag gtagcaagct cagataacga taaaaaagac tgaagaactt
    46861 aatcttcaat ctttcgttgt cgtgactttt taactcctta aagcgtttaa aaataaaggt
    46921 gaacgataca gccttatagc atgtttttga tgtgctcaat ggatttatca cgtcccaata
    46981 aataaatcgt atttggtaat tctgggccat gcatttcacc agatactgca atacgaatag
    47041 gcataaagag gtttttccct ttgattcctg tttctttttg aacagcctta atttgtggga
    47101 aaatattttc tggtttgaag tcttcatctg acatagcttc caacttagcc ttgaaagctt
    47161 gcaagactgt cgaaactgtt tcacctgcca tcacttcttt ttcggcttct gttaattcag
    47221 ggaaatcaga aaagaaaagg tcagtcaatg gaataatctc atctgcagat tttaattgag
    47281 gtttgtataa ttctactagc ttctcagctt tttctgtcaa gcggcctgcc tcttcaagga
    47341 atggtttgca gagggcataa actgtttcaa aatccgcatg tttaagatac tcattgctca
    47401 tccaatccat tttcttctgg tcaaaggcag ctggcgactt gctaaggcga ttttcatcaa
    47461 aaagggcaat cagttgctca cgagagaaga tttcctcttc tccgccagga ttccagccaa
    47521 gaagggcgat gaagttaaag acagcttcag gcatataacc ttttttgcgg taatcttcaa
    47581 tgaattggag ggtattggtg tcgcgttttg ataatttttt acccgtttca gaattgatga
    47641 taagagtcat atgaccaaac tctggcgctt cccagccaag agcttcatag accatcaatt
    47701 gttttggcgt attggcaata tggtcatcgc cacggataac gtgagaaatt tgcatatcat
    47761 gatcatcaac aacaacggca aagttataag ttgggtagcc atctttcttt tgaataaccc
    47821 agtcaccacc gatattacca ccttcaaact cgatatcgcc tttaaccatg tcagtccatt
    47881 tgtaaatacc ggactcatta acagcaagac ggactgttgg aacgatacct gctgcttcac
    47941 gctcagcaat gtacttagct ttttcgtcag ctgacatacc aataaattca ttgatatagc
    48001 gaggcgtttc gccagctgct tcttggcgtt cacgctctgc tgccaattct tcctcagtca
    48061 cgtaagactt ataggctttt ccttcagcta acaattgatc aatatattgt tgataaagtg
    48121 ctagacgttc agactggcgg taattttcat gcgtttctgg gctttcatcc caatccattc
    48181 ctaaccattt taggttttca agttgagaac gttcaccatc ttcaacatga cgtttacggt
    48241 cagtatcttc aatacgaatg ataaaagtac ctccgtgacg acgggcataa aggtaattaa
    48301 atagggctgt gcgggcattc ccgatatgta aaagccctgt tggacttggt gcataacgca
    48361 cacgaattgg tttagacatg cttcttctcc tgttacatat atcactcaga aacctgtggc
    48421 acgaaaaaca agcaacaaat gatgatttga gcttgccaag accttttcag acttcttcta
    48481 aaatctttct tattatagca tattttactt gcttaggcga aaaaaatcag ccctaaaaag
    48541 ctgattttat gttattttga ctaatttgaa ctagttggta gataacgttt aagagtccca
    48601 gcaaattgct caaggttaag actttggata taaatctcac catgacctct aaaggtatta
    48661 acaactcctt cacctgtacc aattgactgc ataaagccat tttctaaatg aatatcataa
    48721 tcaagttctc tgctccatgc tacaacatgg gcattatcaa tagtcattgt gccaccatca
    48781 agtgtgattt tcttgataga tccaaacgag ttagcaagta aggtaccaag gccttcagtt
    48841 gtcatgacaa aaagtccgcc ttgaccacca aaaagtgctt ttccaatatt ttgacgttcc
    48901 attttgtact gtgctgaacc atctagggct agaaaggcac catcatttag acgatattgt
    48961 ttttcaccta gttctaaagc aacaatctgt cctggtgtat tgggtgctaa tgctaattta
    49021 ccatctccat ttgacatagc ttgtgtaatg aacattgatt caccagaaac catggaacgg
    49081 ccgatggctc caactaattt tcctaaacca gatcccttac cattcaattt ggtattcaag
    49141 gttacattct cagtatgata aaccatactt ccttgttgta agtaaactga tcccccatgt
    49201 tccagatcaa tctcaactag tggaaattgc atgttttgat caatcgtaaa tctcattcta
    49261 ttgtcgacca tcttactctc cttgtttgta tgaataactt gatacaatta ttataacgct
    49321 tccctatttc tttgtctaat attttcaata atttttaaaa ataaaaaaga gctgaattca
    49381 gctctacaac ttggctacta actattccat tacttgtgtc atctttccag tatccacatc
    49441 gtagacggca ccgttaataa cgacatcatc agggataaga gaggaggctc ttagcttagc
    49501 catatccttg cggacactgt cttccacatc ttggaaggga aggaaatctt gccctgaaac
    49561 atccacacct aagtgctcat gaatatgctt ggcaaagcct tcattagtaa aagtctgcgc
    49621 gccacaatct gtatggtgga gaaccacaat ctctcgcgtt cccatttgct gctgagaaat
    49681 aaccagcgac cgaatcatgt cttcggtgac acgtccgcca gcattcctta aaatatgagc
    49741 atctcctaga gccagcccca gagcttgggc cacatgtagc cgtgaatcca tacaagtcac
    49801 aatcgctact ttagtcttgg gttttaaggg caaatgagct gtcccatgca aggccacata
    49861 agcctgattg gcagccataa aatgttcaaa ataagacatc aataaactcc ttttgagaaa
    49921 cagcagagct atttttgctg ttagtttgtc ttatcttaac atcttttatg gaaaatagct
    49981 ggattaacct cttagacggt cggtatcgtt cgaaaagtta aaaaaacaaa tgattgggat
    50041 actttcttga caaatttcct cctcatttgc tcttagttta tgatcctcta gctaaaaact
    50101 gcctttaaaa cctgaccaac cgtagtcact ccgacaacct caataccttg agggatatca
    50161 atgccttgca aggcattttt aggagcatag accttggtaa atccaagctt tgctgcttca
    50221 ttaatccgtt gctcaatacg ggtcactcgc cgaatctcac ctgttaaccc gatctcgcct
    50281 aagaaagctt cttgagggct ggttggtttt tccttataac tggatgcgat agccacagcg
    50341 actgccaaat caatggcagg ttcgtctagt ttgacaccac cagccgactt gaggtaggca
    50401 tcttgatttt gtaagagtaa accacagcgc ttttctaaaa ctgccattat taggcttacg
    50461 cgattgaaat caagtcccgt agtggttcgt ctggcattgc caaaaacggt tggtgtcact
    50521 aaagattgca cctctgctaa gataggacga cttccttcca tcgttacaac gacagccgat
    50581 cctgttgccc catctaagcg ttcctctaaa aagacttgac taggatttaa gacctctacc
    50641 aagccgccag actgcatttc aaagatgccg atctcgttag tggagccaaa gcggtttttc
    50701 acagcccgaa gaatgcgaaa ggtgtgatgc ctttcccctt caaagtagag aacggtatcc
    50761 accatgtgtt ctaacatacg aggcccagcc aaggttcctt ccttggtgac atgacccaca
    50821 ataaaggttg caatgttgtt cgtctttgca agctgcatca attctgcagt gacttctctc
    50881 acctgactga ctgatccttg aacacctgta atatcagggc tcatgatggt ctgaatggag
    50941 tcaataatta aaaaatctgg tttaatattt tcaatttctg tgcgaatagc ttgcatattg
    51001 gtttcggcat agaggtaaaa ttcattgtca atatcaccca gacgctcact ccgcagttta
    51061 atctgctctg ctgattcttc cccggacaca taaagaaccg ttcccttatt agcgagctgc
    51121 gtggatacct gcaagagtaa ggtggatttt ccaatacctg gatcaccacc aattaaaatc
    51181 aagcttccag gaaccacacc ccctccaaga actctattaa attcagacat gtcagtctgt
    51241 gttctgtgat aactaatatt atccacatct tttagtttaa ccggtctgga cttttctcca
    51301 gctagactaa cacgggcatt tttgacttct ttgacctcta cttcttccac aaaagaagac
    51361 caggccgagc aatttggaca gcgccctaaa tactttggcg actggtagcc acactcctga
    51421 cagataaagg ttgctttttt ctttgccata gtaatctccc tcccctagac aagacaaacc
    51481 cactcttaaa gaataggtct gctgtcataa gcatttttgt taaatcgctt tactgccctg
    51541 tcgaaccaaa accacctgtt cgttcacctc tggcttggtc accatcagca attaaaaaag
    51601 gcataaaaac cccctgaacg atcctctcac ccacagctaa tgtcacaggg tgatctgtaa
    51661 tgttttgcat ttgtgcaaaa atatgtcctt cattagcctc attgccataa taatctgcat
    51721 caatcacacc tactgaatta atcaggataa tccctttttt tcgtggattt gacgaacgat
    51781 catagaggta aagcacctcg ccatcttgca tgtaggcctt aacccctgtt ggtaccaact
    51841 taatctcccc tggggcaatg gtcacagcct cagcaacaga caggtcataa ccagctgcat
    51901 gagtcgtctc acgttttggt agtaaatcag gattagtaaa gcttgaaaca agctcgaaac
    51961 cacgaatttt tgtcattatg ataggtatat cctttcaagt caatcatatc ctcttattat
    52021 agactattcg taaaagaata gcaaaaaagc ggtcaacttt aaacggacca cttttaatca
    52081 tgccatcaca tctcatcccc acgataacta aagcggatgt gggtgaaatc attatccaaa
    52141 tccttgtctg ccataaaagc tttggcatct tttttcactt gaaccaagtc aataccttgc
    52201 attttggcag catagacaca gccacaatag cattggcggt aaatgtcata ctcctcacac
    52261 atttcaacgg atctgcgata accgttgttt ttcttgaaat cacttggcag gtatttggtg
    52321 gtgtaaacct tttgcacatc gatgcccaca tcattaatgg tttgcgaatt tttatgagga
    52381 ctgatggtta gggcactggc aaagtagtca aaaccaagtt ccactgcttt ttgagcggtc
    52441 ttgtctagtc ggtaatcaaa acagacacgg caacggtccc caccttctgg ttcctcttct
    52501 aagcctcgca cttgtcgaac gtactcattg gggacatagt ccgcttcgag aaactgaaca
    52561 gtattgcctg ttttagcgtt gaactcggag acaaactgtt gtgtcacata ggctctgcga
    52621 tggtattcgt ccttagggtg aatattagaa ttggcaaagt aaaccgtaat gtcagcaaac
    52681 tgcgtcaggt attctagggt gtaagtggag catggggcgc agcagacatg cattaaaata
    52741 ctggggcgca cggattcctt ctcccaaacc ttggccatct gttgcatgac cctgtcataa
    52801 tttatctttt gattgggatt catgttagcg agaatctctt gtaaatcaat cattgtggct
    52861 actttctaat tgttttttct cttgcttgct attataccat atcaggaaag aaagcttgac
    52921 tgctttattg ttcaccaaaa aactccgcta agacgcggag ctgataccat ctattcaaag
    52981 acaaattgat tgtgatacaa ttcggcataa aagccttttt gatgcaatag ctcatgatga
    53041 tttccttgct caatgacctt gccatctttc aacacaataa tgtgatcggc atttaaaatg
    53101 gttttgaggc ggtgagcaat gacaaagctg gttcgacctg ccacgatagc ttccatggcc
    53161 cgttgaattt tactttcggt aaccgtatca acatttgaag tggcctcatc caaaatcaac
    53221 acttcagggt ccgtcagtag cgtcctagca atagaaatca actgcttttg acctgttgaa
    53281 aagacattgt catcatctga gacataggta ttgtaccctt ttggtaagga catgataaag
    53341 tcatgaatat gggtcgcacg cgcagcagtt tcaaccatgt cttgactaat ggtctgatca
    53401 ccaaaacgaa tattatccgt aatggttcct gaaaaaagaa ctgactcttg caacacaatc
    53461 cctacctttt gacgaagact atccaaatcg tagtcacgaa tatcacggcc atcaaaggta
    53521 atcgaacctg catccacatc gtagaaacgg ttaatcaagt tcataatagt ggtctttcca
    53581 gaacctgtcg gtccaaccac ggcaatcatt ttgcccttgg gtgcaacgat tgacacatct
    53641 gataaaactt tttgcccagg aagataccca aaatcgacgt ggttaatcgc cactgcttct
    53701 tttaagctgg tgaacgctgg tgcattttgt ggacgaactt cttcggtttc atcaaacatt
    53761 tcttgaattc ggtgagcacc ggtaaaggcc agctgcaatt ctccccaact agacgcgatt
    53821 tgcatcatgg gttggtaata ttgctgggaa tattgtacaa aagtaaccac taaaccaagc
    53881 gctgccgctg ctggcataga tttgtcactg aggacaattg ttgaaccgac aaaaatcacg
    53941 atagccgtgt taataaggct cattccattc atgactggaa ataattgtcc tgagaacaga
    54001 cggcgtttga aggtggcttg tcgaaccctt tcattatgct ttaaaaaggc tgtcaccgta
    54061 tcttcttgga caccttgtac aataatagcc ttttgtcctg aaatggtttc atccataaaa
    54121 gcatttaaag cactgacttc ttgctgttgg atattggtgt attttcttgc caaacggatg
    54181 ttaaccacta aaaaaatgag agcaactggg gttgatgcga tggttaacaa agctaaacgg
    54241 ctatcttgcc taaacatcat ccagaccagg ccgatgtaaa gggtaatatt agtcaccact
    54301 tgaaccaagg attggttcag cgagttttga atattatcca aatcactcgt gaaacgagaa
    54361 agaatctccc catctttatg gcggtcaaaa aaggcgacgg ttaaacgttc taatttacca
    54421 aacaagccct tgcgcatgcg gttggtcgaa tgtgagacaa cacgtgtaag taagaaacta
    54481 tatattagat tagctaaaac agtaaagaaa taagtcatca aaagcttaaa catcacggca
    54541 ttaaaagctg ataaatcagg gctaaaatgt gtctgaccac tcatcttagc aacgtaataa
    54601 gcctgaccga tttttcccaa ctcagtcaag gactctccta agaagacagg agcttttact
    54661 tgtaaataag ttgctaagat aacggcaaca gcaatgacag taaatgagaa acgatagcgt
    54721 ttaaaataaa accagaaaaa acgtgctgtt ttcatcacta ctcctccctt cctttttgtg
    54781 tctcataaat ttcacgataa atcgcattat tagccaccaa ctctgcgtgt gttccttctc
    54841 caattaactg tccttggtca aggactaaga tcttatctgc cttaactacc gatgaaattt
    54901 tttgagcaac aataactgta gttgtacctt ctaatttatg acttaaggct tcttgaacgc
    54961 gtttttcaga ttttgcatca agagctgaag tggaatcgtc taatataaga attttgggat
    55021 gattaatgac accacgtgca atagacagac gttgcttttg tccgccagac aagttactac
    55081 ctcgctcttc aacttggctc tcataacggc tatccatacg atcaataaat tcttttgctt
    55141 gcgcgatttg agcggctttt tgcatagcct caatatcagc ttttgctgag ccttggcgaa
    55201 ggttatcagc tatcgttcct gaaaagagaa tagccttttg caacacgatg gaaaccgatt
    55261 ggcgcagggt tgtttgactt agggttttaa tcggctttcc tcctaacaaa atttggccat
    55321 cttgaggatc aaataagcga gggatgagct gtgcaagcgt tgatttccca gatcctgttg
    55381 caccaacgat gccgaccatt tgcccagatt caatagcaaa agaaatgtgc ttcaaggttg
    55441 gctcatcatc attaggatat gtaaaactaa catcgtcaaa tacaatgctt cctgagatgg
    55501 tttcttcctt ttcattttca aatgtcatgg caggttctgt agacaatatt tgcctaattc
    55561 tagccataga aacaaaagca cgactaactt gcatccccat ggaaccaacc acaataattg
    55621 aaaacataat ttgcatcata taagtcatga aagaggcaat attcccaatc actgttggat
    55681 ctgtttcgac catggtcgaa acaacattta tagaaacata aactgccaaa taagacacca
    55741 acattaaagc cggctgcatt agtgaaaaac cataaccaat agataaattt aacgccaaaa
    55801 gatcattgga cgtttcttta aatttagtgt attgttgttg ttcttgtaca aatgatttaa
    55861 ccacgcgaac gccacggaga ttttccttag cgatgcgatt aatcttatcc attaaccgtt
    55921 gaaatttacc aaaacgagga cccatttgac gcatcaccaa acccatgatg agggcaatta
    55981 agataaccat tacaacaatg acccaccata attgagggaa tgtctgaact gccataataa
    56041 acgcgccaat aaaaaggatc ggcaaacgaa agagaatttg aaacatcatc atgactaaac
    56101 tttggatttg attgatatca ttagttagcc taaccacaag attaccagca ttaaaagctt
    56161 caatattggc atatgaaaag tcttggattt ttcgaaaggt cttctccctc atatcagcag
    56221 atacaccttg agctatttta gcagctaaaa ccgtattaat cgctccagac attaacccta
    56281 aaagggcaat aataagtaat ggtttcccaa cctcataaat tttctcttga ttattttgaa
    56341 taacagcgct tagcacagat ttaagataat gtggttgcaa gagactactt gcaacaaccc
    56401 caataaccat aaaaaatgag cctaaagcat accatttata acgtaagatt gcttctttaa
    56461 gcatcgttgt ctcctttata agttagcata ttttgcttga gctgttcaat tacttttttc
    56521 gctgtcagca actcttcttt tgtaatttct tttaaaaaat agtgctcgat atccttacga
    56581 cactcccgca acaaaggcaa tttatctcta ccaacctgcg ctaacactac ttgcttataa
    56641 cgcttatcca cttgggaagg catcacattg ataaacccat ttttgaccat acgtttcact
    56701 aaatgactag caactgactt tgagatacga agttgttttt caatatcttt gacaaatatt
    56761 tcttgatttt ggtgtttagc taaaaaaaca agaacataac cttgaggacc tgctagatgc
    56821 tctacatcat atttttttgc aatctcatca ctaatttgtt cgatttgatg tatcaattca
    56881 cgtaaatcac ctatcacttg tgacatctct tccctcctta ttttctttaa tagtttctat
    56941 gataagtatt ttagttctct agataactat tgtcaattaa aatatcttta tttttaaaaa
    57001 taagtttccg aacttaaata actaaaaaga acagggcaaa gccatgacaa cagctcacct
    57061 gatgaagctt attaaacaac attattaata tagctagctc tcttgggaac gccttattag
    57121 ccaagaccat ataccttttc taatagagct aatcaaggtg ttatgttata atagagtgac
    57181 tagctcttga aggagaattt agaatgacaa aacaaaaagt agctatttta ggacctggtt
    57241 cttggggaac tgccctttct caggttctta atgacaatgg ccatgacgtc cgtttatggg
    57301 gaaatattcc tgatcaaatt gaagagataa ataccaagca taccaataga cactacttca
    57361 aagacattgt gttagacaaa aacattacgg caactcttga tttaggtcaa gccctatcag
    57421 atgttgatgc ggtgcttttt gttgtgccaa ctaaagtaac acgattagtt gctagacaag
    57481 ttgccgccat tttagatcat aaagtagtgg tcatgcatgc ctcaaaaggt ctagaaccag
    57541 agacccacga acgtttatca actatcctag aagaagaaat tccagctcat tttcgtagtg
    57601 aagtggtcgt tgtatcaggt cctagtcatg ctgaagaaac tatcgttcgc gatattactc
    57661 tcatcacggc agcctcaaaa gatattgaag ctgcaaagta tgttcagtcc ctctttagta
    57721 accactactt ccgactttat accaataccg acgtcatcgg agttgaaaca gctggtgccc
    57781 tcaaaaacat tattgctgtt ggagctggag ctctccatgg acttgggtat ggagataatg
    57841 ccaaagcagc ggtaattact cgtgggttag ctgaaatcac ccgtctaggc gtcaagcttg
    57901 gtgctgaccc gttaacctac agtgggttat ctggtgttgg tgatctaatt gtaacaggta
    57961 cttctgtcca ttcacgtaac tggcgagctg gagctgccct tggacgtggt gaaaaattag
    58021 aagatattga acgcaacatg ggtatggtta tcgaaggcat cgcaacaact aaggtagcct
    58081 atgaaattgc ccaagacctc ggagtttaca tgccaattac aacagctatt tataagtcca
    58141 tctacgaggg cgctgatatc aaagaaagca tcctcggcat gatgtcaaat gaatttcgtt
    58201 ctgaaaatga atggcattaa gccatgcgtc actaaaataa aaggaggtgc tgatgaccaa
    58261 agtcagaaaa gctattattc ccgcagcagg tttaggcaca cgttttttac ctgcaaccaa
    58321 ggcccttgcc aaggagatgc tacctattgt tgataaacca actattcaat ttatcgttga
    58381 agaagctcta aaatcaggta tcgaagaaat tcttatcgtt actggaaaat ccaaacgctc
    58441 catagaagat cattttgatt ctaattttga attagaatat aatttacagg ctaaaggaaa
    58501 aatcgaactt ctaaagttag tagacgagac cacttctatt aatcttcact ttattcgaca
    58561 gagtcatcca agaggattag gagacgcagt tcttcaagca aagacctttg ttggcaatga
    58621 accttttgtt gtcatgctag gtgatgatct gatggatatt acaaatccaa atgtaaaacc
    58681 attaaccaaa caattgatcg atgactatga agaaactcat gctgcaacca ttgccgtcat
    58741 gagggttcct cacgaggatg tctctaacta cggtatcatt gctcctcaag caaaagcagt
    58801 aaaaggactc tatagtgtgg atacttttgt tgaaaaacca caacctcaag atgcacctag
    58861 tgatttggca attattggac gttacttgct cacaccagaa atttttagta ttttagaaaa
    58921 acaagaacct ggtgcaggca atgaagttca actgactgat gctattgata ccctcaataa
    58981 aacacagcgt gtctttgctc gtgagtttaa agggaaacgc tatgatgttg gcgataaatt
    59041 tgggtttatg aaaacttctt tggattatgc cctgaaacac cctcaagtca aagatgactt
    59101 gaaaacctac atcatccaac tgggcaaagc actagagaaa acaaaaccat aaaaataagg
    59161 agggaaaatc cctccttatt tttatggttt ttaagtcatt tcatcctact agccatctga
    59221 gaagtaacag tgctaaccac tcacttattt ttataaaaac ccaagcacta acacaccaac
    59281 caaaataata ccatagctca ctaaagccaa cattcgcttg gttttcttca ttgttatcac
    59341 tctcatctta gttggaaaaa ctatactcag taacgcacca cccacgacac cgccaatatg
    59401 gcctgccata ctcacgtttg gcataaaaag attcatcagt aaattgacta caattaacgt
    59461 ttggtatgac ttgcccaaat ctttcaacgc ttggttctta cccaaaaaac tcaatactac
    59521 aatagcagca aaaagtccaa ataacgacgt cgatgctcct gcagctactg tttcaggagt
    59581 caaccaaaaa gtaaaggcat tgcccataac acctgataaa acataaagta ataaaaaacg
    59641 gcgtgagccc cagaggtctt cgacgatttg accaacaaaa tatagtgtta atccattgac
    59701 aaaaaaatga ccaaagccga tatgaataaa tatcggagtc accaatcgcc acaactggtc
    59761 tggcattgct tttactagta atccaaacat acctccaact tgataaatag cttgagcacc
    59821 agttgctaaa tgtccatata ccacttgcat tgctataaaa attaagcctg ttaaccctaa
    59881 aaggaaaata gtaataggat atcgttttaa taaccgtgtc atctaagata aacctcctaa
    59941 acagcaatat cataaatcgt ttgatttggc aatcgtattg gcccgctgat aagcttgatt
    60001 gctaacaaca tccactaata aagcttgatc attttgacgt tttaagtcta catccatagt
    60061 tcgtaaagac tagaagagtt ctttgagaat ctcttttttc atcatcttct tatcatacca
    60121 taaattagga aaaaggttca aggctgacaa gaaactagct ctctcaaaaa agattaaaaa
    60181 taaaggcatt ctaaagaatc atttaagaaa actttaaggt tactatcgta gaatgaaaac
    60241 atcctaaaaa gcggtttacc taaaccgttg ggagaatagg ttttcccctt gttttccctt
    60301 ttcataaatc tcctgggcac ctatcttcgt aggtgccctc ccttgtttaa acctgaccag
    60361 ttaaccggct ggttaggttt ttaaatttaa aaagtcaaca gcaaaaatat gatatcaccc
    60421 gcgtgttctt agctctctca attatgagct aaaagcacgc atcaatcaat ctattgatga
    60481 agtttgctgc tttttgatga tctttattgt gactatacta gtaatcttat tgattttagt
    60541 tgacttttac ggtagattcg ctacaatata taggattata caatttaatt taaggagaga
    60601 aaaattacat tgttagatta ttatttggaa tccgatatta ttgaccagaa aatcctactg
    60661 gctattttgt tgacagaaaa agaactgacg atggcagcag cttgttctca aacaactttg
    60721 actgctttaa aaataaagca gtatcttcga caatttaacg ccttatttaa agggtactta
    60781 cgtattgagc ttattaaatc tcgtatttat tgtgaggtat taaatgataa gcgagaagca
    60841 tttttttatg atatttttgc cttatcagat actctaaaaa tgttgacatt cttattacta
    60901 gataatccca aacacaagtc aatcgctgtt tatacacgaa aacaagggat atcccagtca
    60961 aaagcttatc gtcttattca taaattaaaa cattatttac aagacattgg tttaaatatt
    61021 gtagacaata ctgttatcgg agatgaactt aaaatacggt atttgattgc tcttttacat
    61081 aaagagtacg gtattatatt atatgatata caacctgcag acattgaaac gattcatgct
    61141 tttatctttg cagcacaaaa aaacttacaa ccttctgcct ttttagatag acgcttcttg
    61201 ttttttgatg tgctgttgat gttgacttgg aagcgccatc gctatcctgt tcatttgcct
    61261 catttagctc tttttgaaca tctcaaatcc ttgcctattt ttgacaatat caaaaccatt
    61321 gccgtggatg agctagcacc tcgaactcgt gtcacatttt cgtctgatga ttttgactat
    61381 ctctttttaa tttatttaac gactgataac tccttcttga gtgggtactg gacaagtcat
    61441 cagcgacaac aactttacca tttaatcacc aaagatcccg attatcattt actaattcat
    61501 cgtcttcagg cactagttgg aaagtattcc gatattcatg agcatatccc taacttaatt
    61561 ccttttttca aaagaactct ctacaattta caaactttaa ttacctttga tggttattat
    61621 tttgatcaat atcaaggcaa caagctacta ctagataagc ttgaaaccgt tatcaaagat
    61681 tggctttatg acacaggccg tcaaggcagt attagttctg gtcacttaca cttgatgtgt
    61741 ttataccttg agcagatctt ggaaagctct attgctccaa tcaatattac tgttattgag
    61801 agccaagaaa ctgttggtaa cgttatagct aatttcatca cctcaactat cccttcttac
    61861 aaagttgaac tgtcacgggt caatatctta tctgataata tttatcccta tgataaacct
    61921 gtagatctgg ttgtgaccag tcagaagctc ttgcctttct taaaagaact cggtgttttt
    61981 cccaaagaga cccgcttgtt tggtttgagt ttggactgta tccaacagca gcgcgaagat
    62041 ttaatcaaaa ccatcttagc cttgcaccag aaccactacc aaaaacgttt agaagaactt
    62101 tggagagttc cttcttaatt ttttgacagt ccctcctaga tactttcaca gtctaggggg
    62161 gtctttaagg ttgtcacttg caaccttgat aagctctctt tttaaccatt gctattcgcc
    62221 tagaaacagc actggaactg ttttagcggt tcaactcctc ttgtaggatc ttcttccctt
    62281 ttttgaaggt cttatctgaa atttggcata ataaagtgcg ctcccatgtt ctggaagcgc
    62341 actttattat cgcttttact taaccttgta tccactcgat gatggaagtg ccgccccaat
    62401 tcttagattg cttggctaac ttttaagctc ttgtacaagg aagaagtctt tttgactatc
    62461 tgttgattag aggcgagcat taagctctgc tgataatgct tcaaaacctg gttttccaag
    62521 aagcgcaaac atgttacgtt tgtaagcttc aacacctggt tgatcaaatg ggttgacagc
    62581 attcatgtag cctgaaacag cgatggcaag ctcaaagaag taaatagtgt aaccaagggt
    62641 aaactcgtct tgagctggaa gagtgacaaa catgtttggc acaccgccat ctgtgtgggc
    62701 aagaagcaca ccatctgtgg ctttcttgtt aacaaaatca acgtctttac cttgaaggta
    62761 accaagacca tctaggtctt ctgctaattc aggaatgata acatttttac gagggttatc
    62821 aacacgaata actgtttcaa agaggttacg gtaaccttct tggataaatt gaccaagtga
    62881 gtgaaggtct gttgagaagt tagctgaagt tgggtaaatc cctttttggt cttttccttc
    62941 tgattcacca gctaattgtt tccaccattc gccaaagtac tgaagagatg gctcgtagtt
    63001 agccaagatt tcagtgatgt agcctttacg gtaaagcaga ttacgaacag cagcgtattg
    63061 gtaagcaatg ttttcagaga ttttgtctga agaaaggtct ttacgagcag catttgcccc
    63121 ttccataaga gcagtaatat ctgcacctga tgcagcaatt ggaagcaaac caacagcagt
    63181 caagactgag aaacgaccac caacattatc tggcaccaca aatgtttccc agttgttagc
    63241 gtcagcttct accttaacag cacccttaac tttttctgtg gtagcgtaga tacgtttgtt
    63301 agcttcttct tggccatatt ttttaaccaa aagttctttg aacacgcgaa aggcaatagc
    63361 tggttcagtg gttgtacctg atttagagat cacgtttact gagaactctt tgtcttgaac
    63421 gtattcaact aaatcggcaa ggtaagtaga tgaaatagag tttccagcgt aaagaatttg
    63481 tggggctttg cgctctttgg cagtttgtaa gttagcaaaa tgatgattta aaaaatcaat
    63541 cgctgctttg gcaccaaggt atgacccacc aataccgatc accacaagaa cttcgctgtc
    63601 tgacttaatt ttttcagcag cagtcaggat acgtgcaaat tcctctttgt catagttttc
    63661 tggaagatca agccaaccca agaaatctga acctggtcca gttccttcac gcaataactt
    63721 gtcagcttct gtgacttggc cttgtaaaaa atcaatttca tgttgtcccg caaatgactc
    63781 gaggactttt gaataatcaa atgtaatatg tgacatgagt ttcgctccct taaaatttta
    63841 agtttcatta gtatgataac cttttctatc taatatttca atggttttta gtggttttca
    63901 cctgtgaaaa agctaggttt tttgaaaagg ttttcgtttt ttcagacata aaacatgtgt
    63961 caatgcaagc atattctcat catagtggtt ttttaagaga aaataggatt tcatatttcc
    64021 taaaaatatc atgaaaaaag gccctgaggc cgctttaccg taataactta ttttaaggat
    64081 tttatcattt caacacgggt aataacccca tcatgcatat gatcaatgca taaagccaca
    64141 cccacaaagg caattgaagc cccaatcacc tgtaaatact ttctcatgct atcttcttaa
    64201 cattacttac tctcattatc taaaaatggc aatcatttga atacttaaaa agcaaagggg
    64261 gagaatagca ctagtacgtt tttaagtaga tatcaaaatg actaatttct tcactattaa
    64321 aaatcttatt atctttatac cttttaaaga aactgtctcg acttaaaagc ttatcatcct
    64381 tat
//
LOCUS       DAUGSW010000008        54988 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUGSW010000008 DAUGSW010000000
VERSION     DAUGSW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54988
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.008"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            111..272
                     /gene="sagA"
                     /locus_tag="VIB18_000572"
     CDS             111..272
                     /gene="sagA"
                     /locus_tag="VIB18_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEQ8765601.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            494..1444
                     /gene="sagB"
                     /locus_tag="VIB18_000573"
     CDS             494..1444
                     /gene="sagB"
                     /locus_tag="VIB18_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEQ8765602.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1441..2499
                     /locus_tag="VIB18_000574"
     CDS             1441..2499
                     /locus_tag="VIB18_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEQ8765603.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNAPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQVLPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2519..3877
                     /locus_tag="VIB18_000575"
     CDS             2519..3877
                     /locus_tag="VIB18_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEQ8765604.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEMILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3852..4523
                     /locus_tag="VIB18_000576"
     CDS             3852..4523
                     /locus_tag="VIB18_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8765605.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSISMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4520..5203
                     /locus_tag="VIB18_000577"
     CDS             4520..5203
                     /locus_tag="VIB18_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEQ8765606.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLMALSYQDFLDV
                     LLSLFQFVIIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5226..6149
                     /locus_tag="VIB18_000578"
     CDS             5226..6149
                     /locus_tag="VIB18_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765607.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6158..7285
                     /locus_tag="VIB18_000579"
     CDS             6158..7285
                     /locus_tag="VIB18_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765608.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            7282..8400
                     /locus_tag="VIB18_000580"
     CDS             7282..8400
                     /locus_tag="VIB18_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765609.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWILSAIA
                     IFQSGGTLSQAWPYLLALMGTALALISFSSLLLKPTKL"
     gene            8971..11703
                     /locus_tag="VIB18_000581"
     CDS             8971..11703
                     /locus_tag="VIB18_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEQ8765610.1"
                     /translation="MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTSLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDNEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFPKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      11868..11983
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            11981..12481
                     /locus_tag="VIB18_000582"
     CDS             11981..12481
                     /locus_tag="VIB18_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEQ8765611.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRVSEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMLTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12675..14633
                     /gene="ligA"
                     /locus_tag="VIB18_000583"
     CDS             12675..14633
                     /gene="ligA"
                     /locus_tag="VIB18_000583"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEQ8765612.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYQHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPYQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            14647..15669
                     /locus_tag="VIB18_000584"
     CDS             14647..15669
                     /locus_tag="VIB18_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8765613.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            16073..16270
                     /locus_tag="VIB18_000585"
     CDS             16073..16270
                     /locus_tag="VIB18_000585"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEQ8765614.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16305..17021
                     /gene="atpB"
                     /locus_tag="VIB18_000586"
     CDS             16305..17021
                     /gene="atpB"
                     /locus_tag="VIB18_000586"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEQ8765615.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17039..17533
                     /gene="atpF"
                     /locus_tag="VIB18_000587"
     CDS             17039..17533
                     /gene="atpF"
                     /locus_tag="VIB18_000587"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEQ8765616.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17533..18069
                     /locus_tag="VIB18_000588"
     CDS             17533..18069
                     /locus_tag="VIB18_000588"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEQ8765617.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18085..19593
                     /locus_tag="VIB18_000589"
     CDS             18085..19593
                     /locus_tag="VIB18_000589"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEQ8765618.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19609..20484
                     /locus_tag="VIB18_000590"
     CDS             19609..20484
                     /locus_tag="VIB18_000590"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEQ8765619.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20646..22052
                     /gene="atpD"
                     /locus_tag="VIB18_000591"
     CDS             20646..22052
                     /gene="atpD"
                     /locus_tag="VIB18_000591"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEQ8765620.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22065..22481
                     /locus_tag="VIB18_000592"
     CDS             22065..22481
                     /locus_tag="VIB18_000592"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEQ8765621.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22747..23004
                     /locus_tag="VIB18_000593"
     CDS             22747..23004
                     /locus_tag="VIB18_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEQ8765622.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23069..24340
                     /gene="murA"
                     /locus_tag="VIB18_000594"
     CDS             23069..24340
                     /gene="murA"
                     /locus_tag="VIB18_000594"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8765623.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24344..24532
                     /locus_tag="VIB18_000595"
     CDS             24344..24532
                     /locus_tag="VIB18_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8765624.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            24568..25107
                     /locus_tag="VIB18_000596"
     CDS             24568..25107
                     /locus_tag="VIB18_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEQ8765625.1"
                     /translation="MLTRKKRKRVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFK
                     PAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKP
                     YATGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVP
                     NVQPGLTVDYRTGQIAINL"
     gene            25390..26433
                     /gene="pheS"
                     /locus_tag="VIB18_000597"
     CDS             25390..26433
                     /gene="pheS"
                     /locus_tag="VIB18_000597"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8765626.1"
                     /translation="MDLQAQLEELKTKTLETIQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            26643..29048
                     /locus_tag="VIB18_000598"
     CDS             26643..29048
                     /locus_tag="VIB18_000598"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEQ8765627.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPIHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRELTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSDHVQAGQLPTEPVEVSTSLDYVNVRLGTEFTFEDIQTVFDQLGFGLTGDETSFT
                     VAVPRRRWDISIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQVLRRKVRGLAE
                     GLGLTEIISYALTTPEKAIEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGVLDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKLPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTSIKLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            29158..29535
                     /locus_tag="VIB18_000599"
     CDS             29158..29535
                     /locus_tag="VIB18_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEQ8765628.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            29528..29914
                     /locus_tag="VIB18_000600"
     CDS             29528..29914
                     /locus_tag="VIB18_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEQ8765629.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            29987..31063
                     /locus_tag="VIB18_000601"
     CDS             29987..31063
                     /locus_tag="VIB18_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765630.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GIGNITIAQAVLLQTFLLSALGSGLGLLGTWLTSLVLPEAVPFQSNWLVYLAILVSMV
                     CFALLGTLFSVFSIVRIDPLKAIG"
     gene            31073..31741
                     /locus_tag="VIB18_000602"
     CDS             31073..31741
                     /locus_tag="VIB18_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765631.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGIAGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLEYCDKVYRMQDGEL
                     RQER"
     gene            complement(31845..32762)
                     /locus_tag="VIB18_000603"
     CDS             complement(31845..32762)
                     /locus_tag="VIB18_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEQ8765632.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRAVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            32913..36128
                     /gene="rexB"
                     /locus_tag="VIB18_000604"
     CDS             32913..36128
                     /gene="rexB"
                     /locus_tag="VIB18_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEQ8765633.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSKKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKRIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQITPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            36089..39757
                     /gene="addA"
                     /locus_tag="VIB18_000605"
     CDS             36089..39757
                     /gene="addA"
                     /locus_tag="VIB18_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEQ8765634.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERYSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGNVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFALDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQE
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            39897..40709
                     /locus_tag="VIB18_000606"
     CDS             39897..40709
                     /locus_tag="VIB18_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8765635.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVHLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLEAPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            40850..41026
                     /locus_tag="VIB18_000607"
     CDS             40850..41026
                     /locus_tag="VIB18_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEQ8765636.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(41154..41516)
                     /gene="mscL"
                     /locus_tag="VIB18_000608"
     CDS             complement(41154..41516)
                     /gene="mscL"
                     /locus_tag="VIB18_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEQ8765637.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            41647..43461
                     /gene="dnaG"
                     /locus_tag="VIB18_000609"
     CDS             41647..43461
                     /gene="dnaG"
                     /locus_tag="VIB18_000609"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8765638.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGKEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFHLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPMPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     ELLYQRLKQQGHITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            43470..44579
                     /gene="rpoD"
                     /locus_tag="VIB18_000610"
     CDS             43470..44579
                     /gene="rpoD"
                     /locus_tag="VIB18_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEQ8765639.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            44815..45153
                     /locus_tag="VIB18_000611"
     CDS             44815..45153
                     /locus_tag="VIB18_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEQ8765640.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            45291..46145
                     /gene="rfbD"
                     /locus_tag="VIB18_000612"
     CDS             45291..46145
                     /gene="rfbD"
                     /locus_tag="VIB18_000612"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEQ8765641.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            46264..47418
                     /locus_tag="VIB18_000613"
     CDS             46264..47418
                     /locus_tag="VIB18_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEQ8765642.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSRPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLATADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDSRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTK
                     QKGQLAELINQVDAGFDSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            47408..48340
                     /locus_tag="VIB18_000614"
     CDS             47408..48340
                     /locus_tag="VIB18_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8765643.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            48343..49146
                     /locus_tag="VIB18_000615"
     CDS             48343..49146
                     /locus_tag="VIB18_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765644.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            49146..50351
                     /locus_tag="VIB18_000616"
     CDS             49146..50351
                     /locus_tag="VIB18_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765645.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNTEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            50376..51383
                     /locus_tag="VIB18_000617"
     CDS             50376..51383
                     /locus_tag="VIB18_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8765646.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTIYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEVSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            51380..53125
                     /locus_tag="VIB18_000618"
     CDS             51380..53125
                     /locus_tag="VIB18_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEQ8765647.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQIRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMGPYFENFEEKEAVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKTESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            53122..>54988
                     /locus_tag="VIB18_000619"
     CDS             53122..>54988
                     /locus_tag="VIB18_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8765648.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTTQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQDTIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTS"
BASE COUNT        17503 a         9266 c        11063 g        17156 t
ORIGIN      
        1 acaattgagc tagccttgtc cttgttgtgt taactttatt tttaaaataa ggttaaaaat
       61 aaacgactcg tgttcttatc agttacttat tagataagga ggtaaacctt atgttaaaat
      121 ttacttcaaa tattttagct actagtgtag ctgaaacaac tcaagttgct cctggaggct
      181 gctgttgctg ctgtactact tgttgcttct caattgctac tggaagtggt aattctcaag
      241 gtggtagcgg aagttatacg ccaggtaaat aatctattta gcatctctat gtgatagtga
      301 tattaaggta atgagtttgc tagcaactaa gttatctttg gtaacttctg attatagatg
      361 aatggcatag aggtgttaga aaacatgaga caaaagtaat cttcttgatg ctaacgtctc
      421 aggtaattag caggtactag acagtacctg ctaattacta tatgtttagt aaaatgagat
      481 aggaaagata attatgtcat tttttacaaa ggaacaacaa cctaaagaga attgtccgcc
      541 aataactgtt gaaaaagcaa ggcaattgtt tgaatttaat acaaaccact tgtccttatc
      601 ggattaccat catcaaacgg tgctaaaaac gtcaaagcag ctagttgctc aacatttaat
      661 gcctaatgca accgataatc ttagtcaaca ttttttgatg aactataaag ctaataataa
      721 ttatttaggc ttccaagcta gtattgtcga cttttttaca gattctgccg ttgctaattt
      781 ttcaagtagt tacgtttatg aaagtcagga aaagataatt cgtttaccaa aacctaccaa
      841 gatatcaact gctctgtcga catgtattat aaaacgaaga agtcatcgtc aattttcaga
      901 tagacaaatg cctcttcaag atttatcaaa cattctttat tatgcatgtg gtgttagttc
      961 acaagcatca attagagatg gagcatcaga taagattaca ctcagaaact gtgcttcagg
     1021 tggaggttta taccctattc atttagtttt ttatgctaga aacatcagta aattaataga
     1081 tggtttctat gaatatctac cctatcagca tgcactaagg tgttatcggc atagctctga
     1141 ggaaaacgtt agagattttg cggaatacgg tgctattaat gctgaaaatt gtaatattat
     1201 tattatttat gtctaccatt acatgaaaaa tacacgtaaa tatgggaatc aggcgactgc
     1261 ctatgctttt attgaatcag gagaaatagc ccagaatatt caattgactg caactgcctt
     1321 aacttatgga agtattgata ttggtggtta taataaggaa tatctccaag aattattaga
     1381 tttagatggg ctaggagagc atgtgattca catgacactc gtaggaacta aggagtctca
     1441 atgaaatatc aacttaatag taatgttcgt gtcgtgacat ttcaagatac attttgtttt
     1501 agaaaaggaa tctgggactt taatgaagcc attctagatt tgacacaaga acctcaaaat
     1561 ttaaagatag tttatcaaga aatagtttca cagttggtta agggagtagc cattgatact
     1621 gaaacttatg aaaatacttt agaacctgag acgttcgcta atttaatgga agtcatttca
     1681 ggcttgtatt acaatgatat gctgatgctt gaggatgact acaatcttga agaaaatgtc
     1741 atgaaaattt taatgggtaa tttccgtttt atggcgcaag caggtcatat ggtaagcaat
     1801 gctcctgttt tgtttatcag tgattcgact tatgttaatg aatctgctga gttgctagct
     1861 gaacaactgc atttacaatt gcaagtggct agtgatgact taaaaatgtt aattcagcag
     1921 acagatgtta gttcgcgttt agatgctttg gagcatcgcc gtaacatgaa ttgtttatca
     1981 gaagccttgt gcgattacca aagtattatt atttgtcaag aacgcttgaa tattatgatg
     2041 ttgcgacact tgaatgaagt tagcgtagct atgaaaaaac aattagtgat tggttttgta
     2101 gatggaccat tcttgcacac ttgtactttg aatcctcccc atagtgctga ctttgatagc
     2161 ttagaaagaa gagttttggc acgtttacaa gactcaactc tctatcaaca ttttgctaat
     2221 caggttttac cagccacaca agatgtgagc caggcctatt taccattgtt aaatgtttta
     2281 atgaatttag tcgttagcga agctttcatt attgctcaaa caggtagttc taaatttgag
     2341 ggacgtttat taagcattta cttaccgacg cttgagattc aggtccaaga tattttgaaa
     2401 atgtctaatt cacagacaca aggagctttg gcaaaattaa agtatgagga tcagcagata
     2461 tcaacacgtg agattgttaa aaaactcctt gacgagtaac ctataaggag aatctattat
     2521 gttatactat tatccttctt ttaatcatat ttttgatgaa ttaaaaagtt taagtggcaa
     2581 tcgaacaggt atcttaaatc aatctcaagt tccagtttgc aaccatcctc acgatgttta
     2641 cttaaaaagt attactggcc aaatgccaga ttatcataaa caatttatag gtgagttgag
     2701 tcaagttagt tatcacatta ttggttacgg cagttactac gaagaagcac ttatcaagta
     2761 tttaggagaa agtattgaac gctatgctac tgtaattgcc ggagacttac tatcagatcg
     2821 gattgtctat gcttcttata atgagttaaa actgttacat aaagtgatgc ctttagaata
     2881 cttgcaagtg tttacccaag aacagatcgc attatcttgt gacttgcaaa tgatgatgtg
     2941 cgataaaatg gtaactgaga acgatgtatt gggctgggtt aaatgtccca tgttctttga
     3001 ggacgcagag atgtatgttc cagctcaaat gctttgtgtt gggtataaaa caaatgagac
     3061 tgtaggagaa agacggataa taccaggatt ttctacggga acagcttctc acaaaacgtt
     3121 agaagcggct atgtgcaaca gtttgattga atacatccag atcgattcaa tgatgcttag
     3181 ctggtatact aagaagcctt gccccaagat tattgttgat gatcctgata ttgaaatgat
     3241 tttagaagaa gctagactgg gaaaagacag tctatacgac attattccta tcgatatgac
     3301 tgtaggagaa gataatcctc tttatacgtt tggaatcatt ctcaaaaata aatatgatga
     3361 agggccttac ctcttgtttg gagtgcaggc tgggttagat cctaaacatg ctttgctaag
     3421 agggatcatg gaagcttcag ctatcagcta tagttactac tataatcttt tatatcaaaa
     3481 agcttccctt gcaaatattg aatgcgaaga acctttgttt ttagatttag atagtaatgt
     3541 tttctattat gcacatccca aggaccaaga ccataaatgg aaggcctttg aacctttgat
     3601 ttcaggagaa gttctgttaa gtgatttgga agatcattct ggtaaagata aaaaagaaga
     3661 tttgaagact ttattagctt atgctaagaa agtcagtcct aatgctgtct ttttagatat
     3721 tacacctcct gaagctctag aaaaaggctg gtacgtcacg cgagttctga tgccagaact
     3781 tcttgaaatg tgtataccag catttccttt tgctaatcac ccacgaatga gacagtttgg
     3841 aggtgtaaca aatgcctttg tccatccaat gccttaatct ttgttttttg ttggtaactt
     3901 tttgtccttc aatttctatg caagctattt ttggaaagga agatagtggt tatgcattta
     3961 atttaattgg ttttctaaga gcaactctga tttatgacat tttggctttg gtaagtattt
     4021 atgttttgtc acctcaaata accttgtctc ttgaaagtat tgatagtaag acgttcttta
     4081 tgggacttgt attttgcgtc ttgatagtac tgattgaact cgttttctta catggtttac
     4141 gttgttggca aaaaaaacaa tggcttcctg caactttctc gtttgtagga acgacaaatg
     4201 attggtctaa gattggctat cctttattac tagctttatt tgaagagacg atttatcgtt
     4261 ttttgtggtt taatatatta gcttttcaat ggcatttacc aacaattatt gttttaattg
     4321 taactagttt ttgctatgct ttaaatcact tattgatggg gaaatccatt ttttatgcta
     4381 agttggtaac aggcatcatt tatggtagta tttacatgct gactagtcaa ttgtggttgg
     4441 ttgtgataat gcatgtagga ggtaacttgc tagttgagtg tcttagccat cttcaaacaa
     4501 aaaagaagaa ggaggtgaca tgatgctatt ggttttgctg tcgtttttag gtctaactac
     4561 tctttggttg accagttatc gaagacggtg tttggctaga tggcatcttc aatggttaat
     4621 ggccttatcc tatcaagatt ttttagatgt cttactgagt ctgtttcaat ttgtcattat
     4681 tatacttgtt ttattctttt actcagctac tattaatcta ggagaggttc tgaccttttt
     4741 gacacaaact agctggcatt ggcagattct ttgttattta gtgttatatc ttatggccat
     4801 catagagatg acgcttttag ttttaattct tatctttgat gttttgctcc agaaagacag
     4861 tcgattgctc tttaaaaaaa taacttggct gccttttaga caagataaac cagtcttaag
     4921 tatactttta ctaggcatag ttattctagt agacagtctc ttttatttgg gcttgcttat
     4981 attattagga gaacagtcgc taacaagttt agcaacgctt attttaggtt atgggatagt
     5041 caaggcttgt cgctattcag gttggttaaa tgtactatta gctttttgtc ttttcactat
     5101 agttggacta tgggcagtta cggcaacttt attatatggt tggctagtag gtgcgatgat
     5161 attaacggtg acttatttga tgattagttg caaagagtat tagcaatatt aaaaaggagt
     5221 gatatatgag ttttgtacaa ttaacaaatg ttgtcaagtc ctacaaaaac ggcaagaaag
     5281 ctgtcaatga tgtttccttg tctattgaag caggtaatat ttatggtctg ttaggaccaa
     5341 atggtgctgg taagtctacc ttgattaatc ttatcttagg cttgatccct ttgagttccg
     5401 gtaaaattac tgttttaggg caatcccaaa agactattcg aaaaataagt tcgcagatag
     5461 gttatgttcc tcaagacatt gctgtttatc cagacctaac tgcttatgaa aatgtagagc
     5521 tatttgggtc actttatggc ttaaagggag ctcagcttaa aaaacaagtt ctaaaaagtt
     5581 tagaatttgt gggactacac tcccaagcta agcagtttcc aagtcaattc tcaggaggaa
     5641 tgaagagacg gttaaatatc gcttgtgcgc tagttcattc acctaaatta atcatttttg
     5701 acgaaccgac tgtagggatt gatcctcaat cacgtaatca tattttagag tcgattcgtt
     5761 tgctaaacaa agaaggtgcc acagttattt atacgaccca ttatatggaa gaagtagagg
     5821 ctctttgtga ttatattttt attatggatc atggtcaagt tattgaagaa ggacctaaat
     5881 ttgaactgga aaaacgttac gttgcaaatc tagcaaacca gattattgta actctaacag
     5941 attcacgtca tttggaactg gcagataagc ctgattggtc tttgatagaa gatggagaaa
     6001 aactcatgtt gaagattgat aatagtgata tgacatcagt tgttcatcag ctcacacagg
     6061 ccaatattac ttttagcgag attagacata accatttgaa tttagaagaa attttcttac
     6121 acttaacagg taagaagtta cgagattaga ggttactatg gttttatttc atttaatcaa
     6181 aaaagaaagt ttacagattt ttagaaaccg aacagcctta ttgatgatgg tgatttttcc
     6241 aattttgatg atcgttattt taagttttgc ctttaaatca agttttaata ctgcgacaac
     6301 agtccctaaa ttgaccattc gttaccagtt agagggtgaa aaaacggatt accagaaaaa
     6361 ttttcttgct tttttaaaag ttttaaacca aaaacttcat ttagaggcta aacctagtaa
     6421 ttctcttgaa aaagatcgac aaagagtcag tgaaggagcc ttaacggctg ttttagaagt
     6481 gaagaagaat cagaccatta aggttattac taataatatt aatcagcaaa atgcagattt
     6541 gatcaatatg ctagtaaaaa attatgtaga taatgctaaa acttatgact cgatagcagc
     6601 tctttatcct caacaattaa atcatatcag aaagcgaagt gtggactatg ttaaggtcag
     6661 ttcaatacag acaagtaaag gaatgacatc agctgattat tatgctattt ccatgtttac
     6721 catgattact ttttatagta tgatgtctgc gatgaacctt gttttgtcag atcgtcaaca
     6781 acggattaca aatcgtattc acttaacagg agtttctcca agtcttttgg tctttggaaa
     6841 attaataggt gctatgttag caacaactgt tcaattgagt cttttataca tttttacaag
     6901 gtttgtttta cgagttaatt ggggcactaa tgagtggatg cttattggta taacagcctc
     6961 cttagtctat ctctctgtag ctataggtat cgggctaggc ataagcatta aaaatgaggc
     7021 ttttttaacg gttgcatcca atactattat tcctatattc gcctttttag gaggcagtta
     7081 cgttccattg acaacattac acagctctat tattaatcaa ttgtcgaata tatctcctat
     7141 taaatgggtt aatgatagtt tgttctatct tatttttggt ggtcaatata atccgattcc
     7201 tgtaactttg atcgttaata ttagtatcgg aacaattttt ataatattgg cattgatagg
     7261 tatgagaaag caggtgacga catgatttgt tttataaaaa ctctatttgt taagataaag
     7321 cgcaaaaaaa caagttatgt gacattcttt ttaatgccta ttttaacgac acttttggct
     7381 ttatctttga gtttttcaaa taataatcag gctaaaattg ggatattaga taaagataat
     7441 agtcagatat ctaaacaatt tattgctcaa ctaaagcaaa acaaaaagta cgacattttt
     7501 accaaaatca aaaaagagca tattgatcac taccttcaag ataaatctct agaagcggta
     7561 ttgactattg acaaaggatt ctcggataaa gtgttgcaag gaaaatctca aaaactcaat
     7621 atacgttcga ttgctaatag cgaaattaca gagtgggtaa aggcacagac caattatcta
     7681 ttggaaaatt ataatattat aggggatgtg gctctaggta acgaagatac ttttaataga
     7741 attctccaaa aaaaccaaca gttaaattat gatgttaagc aagtaacttt gacagaccga
     7801 tcacgtagca aagcagtatc ttccacaacg acaggatttt tgcttattct aatgttaggt
     7861 agtacgagcg tgatttacag tggtatttta gcagataaat ctagtcagtt ataccatcga
     7921 ttaatgttat cgaacttatc tcgttttcgc tatatgttga gttacgtctg tgtaggattt
     7981 gttgctttta cgattcaaat tgtcattatg ctgagtttgt taaaagtatt taatattagt
     8041 ttttttgttc cgacatcact tcttttgatt atttttttcc tttttagttt attagcgata
     8101 ggctttggcc tgctgattgg agctatcaca caaaattccc aacaaagtag ccagttagct
     8161 aatcttattg taatgccgac ttcaatgttg gctggctgtt tatggccatt gtctattacg
     8221 ccttcttata tgcaagcaat tggtaagtta ttaccacaaa attggatttt atcagccata
     8281 gctatttttc aaagtggagg gaccttatct caggcttggc catacttgtt agctctaatg
     8341 ggaacagcac tagctttgat tagtttttca agtttattat taaaacctac caaactataa
     8401 ttagtctttt gttaaaaaat actttcctaa ttagctaact accaggtagc ccttttattg
     8461 gcttatatgc aataaaaggg ttgctttttg cttatatttt ctctagtgca cttatctttt
     8521 gttaaaagcg attgcgatgt tactgttgtt attgtgtttt ttagagagca tattatcaaa
     8581 agcgacccct ctataaagtt cgtttttgtt gataaaaggg ttgtcaaagt attttaaaaa
     8641 acgttttcaa taaacataaa aactaatgtt attaaaaaaa gttgtgaaaa cgtatttatt
     8701 ttatgggatg tttttgttac aataagcatg tatcgaatgc tataaagctg tcttgttcgc
     8761 tatcaggggt gcttgtgatg ttatgtcaga tcaaacaagt ctttaattgg gtgacttaac
     8821 agattaaaag aaaagatcta atcgtgttac ttgatagtat aattaatgca aacagaaagt
     8881 gtatcccaat tcatagtctc aggtggaggt taatattcaa aaataaaatc ttgttgttgt
     8941 cttaaactaa tcacattaaa aggagatatc atgattaaca agaaatatat aatacctgtt
     9001 tcattgttga cactagctat tacgcttact agtgttgaag aagttacttc acgccaaaat
     9061 ttgacttatg ccaatgaaat cgtaacacaa aggccaaaga gagaatctgt tattagtgat
     9121 aaatcgaatt ttcccgtcat atcaccttac ctagcaagtg tggattttgg tgagagaaaa
     9181 acatctttgc caacacctga taaaggagta aaagtaacta ctgaacagtc tattgctcaa
     9241 gtaagaaagg ggcctgaaga aagaacctat actgttactg gcaagattac gagtgtgatc
     9301 aatggctggg gaggctatgg cttttatatt caagataatg aaggtattgg actttatgtt
     9361 tatcctcaaa aagatttagg atacagtaag ggagatattg ttcaattaac aggtacactt
     9421 actcgcttta aaggtgattt acaactccaa caggtgactg cacacaaaaa gttagagtta
     9481 tcttttccaa cttctgttaa agaagcagta atatcagaat tagaaacaac aacaccctca
     9541 acattagtta agttatctca cgtgacagtt ggagaattat caactgatca atataacaac
     9601 acatctttcc ttgtaaggga tgatagtggt aaaagtatag ttgttcatat agatcatcgt
     9661 acaggggtta aaggggctga tgttgttact aaaataagtc agggtgattt gattaacctc
     9721 acagccatat tgtctattgt tgatggtcag ttacaattaa gaccgttttc tcttgaacaa
     9781 ttggaagtgg ttaaaaaggt cacaagctca aatagtgatg cttcatctcg taatattgtg
     9841 aaaataggcg agattcaagg agccagtcat acgtcgccac ttctcaaaaa agcggtcacc
     9901 gtagaacagg ttgttgtcac ttatttagac gattccactc atttttatgt tcaagatctt
     9961 aatggtgatg gtgatttagc gacttcagat ggtattcgtg tttttgctaa aaacgctaag
    10021 gttcaagtcg gcgatgtttt gaccatttca ggtgaagtgg aagaattctt tggtcgtggt
    10081 tatgaggaac gtaagcagac tgaccttacc atcacccaaa ttgtggctaa agcagtgacc
    10141 aaaacaggga cagctcaagt tccatcgccg cttgttttag ggaaagatcg tatcgcgcca
    10201 gccaatatta ttgataatga tggtttgcgt gtgtttgatc cagaagaaga cgctattgat
    10261 tattgggaat caatggaagg catgttagtg gcggttgatg atgctaaaat ccttggtcca
    10321 atgaaaaata aagaaattta tgtcttacct ggctctagta caagaccgtt aaataattca
    10381 ggtggagtat tacttccagc taattcttat aacacagatg tgattcctgt tcttttcaaa
    10441 aaaggcaaac aaattattaa agcaggagac tcttacaaag gaagattagc tgggccagta
    10501 tcttatagtt atggtaatta caaggtcttt gttgatgaca gcaaaaacat gccaagttta
    10561 atggatggtc atctaaaacc tgaaaaaaca aacttgcaaa aagaccttag caagttaagc
    10621 attgcttctt acaatattga aaacttctca gccaatcctt cttcaactaa agatgagaag
    10681 gtcaaacgga ttgccgaatc ctttattcat gatctgaatg ctccagacat tattggatta
    10741 attgaagtcc aagataataa tgggccgact gatgatggga caacggatgc gacacaaagc
    10801 gcacaacgcc tcattgatgc tattaaaaaa ctaggtggcc caacttatcg ttatgttgat
    10861 attgctccag aaaataatgt tgacggaggt caaccaggtg gtaatattcg aacaggattc
    10921 ctttatcaac cagagcgcgt cagtctttct gataagccaa aaggcggtgc tcgtgatgct
    10981 ctaacttggg ttaatggaga attaaacctt agtgttggtc gaattgatcc aactaacgcc
    11041 gcttggaaag atgttcgtaa atcgctagca gcagaattta tcttccaagg tcgtaaagtc
    11101 gttgttgttg caaatcattt gaactctaag cgtggggata atgctcttta tggtcgtgtg
    11161 caaccagtca cttttaaatc tgagcaaaga cgtcacgtct tggctaatat gctagcacaa
    11221 tttgcgaaag aaggggcaaa acaccaagct aatattgtga tgctaggtga ctttaatgat
    11281 tttgaattca caaagacgat tcaattaatc gaagaaggtg atatggttaa cttggtgagc
    11341 cgacatgata tttcagatcg gtattcttat tttcaccaag gcaataatca gacccttgat
    11401 aatatattag tttcacgcca tttacttgat cactacgaat ttgacatggt tcatgtgaat
    11461 tccccattta tggaagctca tggacgcgca tcagatcatg atccattgtt acttcaatta
    11521 tcatttccta aagaaaatga taaggcagag tcttctaaac aaagtgtaaa agctaaaaaa
    11581 acttcaaaag gaaaactgtt gccaaaaaca ggagatagtc ttgtttatgt gataacgcta
    11641 ctaggaacgg ctagtttatt agtgcctatt ttattattga ctaaaggcaa aaaggaatca
    11701 tagcgatttg aagaattgga gttcataaag agtcgttaaa ggcttgatat acttacgtta
    11761 gaccttaagc taaaatggat gactatataa aaactaagat tgatcacaaa agaagataac
    11821 aataagacag ctttacttgc taaagacttt tgtcaagcta attgttttat ggtacaatgt
    11881 aaccgttgct ttgcaaccct tggtgcttag ttccctttca ccaagcatat tagaaacgta
    11941 gatagctttt gagagttatc cagacgttaa aggagaaaaa atgacaaaat tgactgtaca
    12001 cgactatgtt cacattgggc tagtagctgc cttgtatgtt gtcttaacta ttaccccacc
    12061 tttaaatgcg atttcttatg ggatgtatca atttagagta tctgaaatga tgaatttctt
    12121 agctttttat catcgcaagt atattattgc ggtgactctt ggatgtatga ttgctaactt
    12181 ttatagtttc ggactgattg atgtctttgt aggcggcggt tcaactctta tttttgtgac
    12241 cttaggtgtt attttgttta gtaagtatca aaaagattat ctttttaatg gcatttttaa
    12301 taaagctttt gtttactttt ctttcttttt tgcaacttcc atgcttactg tagcaatcga
    12361 actttacttc tttggagctc catttttatt aacatggttt acaactgcgt taggagaatt
    12421 agtatctctg ctcataggat cacttattat tgataagttg tctcaaagaa tttcctttta
    12481 gtaatgcatc atactcaaaa gagttgggtc aatacccttc tcttttttat gttgtttgta
    12541 atgttaaaat cgttctagat agaaatattt aacactttag ctaatagtac catatggagt
    12601 ggccaacgat tacttttgat gttgttatga tatagaaata gctcatttgt tatcttttat
    12661 gataaaataa aagtatgaaa aaacgcataa aagaattaac agatcttctt aaccgttatc
    12721 gttatgacta ttatactaaa gatgccccat cagtttctga cagtgactat gataagcttt
    12781 atcgtgaact ggtgacttta gagcagtcat atcccgagta tgtcttgcaa gatagcccaa
    12841 cgcagcaggt tggagggact attttaaagg ggtttgaaaa atatcaacat cagtatccgc
    12901 tttttagttt gcaggatgct ttttcacgtg aggagctgga tgcttttgat aagcgcgtca
    12961 aggccgaatt tccgaatgcc acctatctag cagagttaaa aattgatggt ttatctattt
    13021 ccttgagtta tgagaatggc ttcttacagg ttggagcaac acggggtgat ggcaatatcg
    13081 gtgaaaatat cacagaaaat atcaaaaaaa taaaggatat tccttaccaa ttgagtgagc
    13141 ctttaaccat caccgttcga ggagaggctt acatgtctcg tcagtccttt aaagcgatca
    13201 atgaagcacg ccaagaaaat ggggagactg aatttgctaa tcctagaaat gctgccgctg
    13261 ggacactaag gcagctagat acgtcagtgg ttgctaagcg tcaactagcc acttttttgt
    13321 atcaagaagc tagtccgaca gctagaaatc aacaaaatga ggtcttagca gaattagcag
    13381 atctaggttt ttcagtaaat ccgtattatc aactcacatc gtctatggat gagatttggg
    13441 attttatcaa aactattgag gcaaaaagag atcaattagc ttatgacata gatggcgttg
    13501 ttattaaagt taatagccta gccatgcaag aagagctagg gtttacggtt aaagctccac
    13561 gctgggccat tgcttacaaa tttccagcag aagaaaaaga ggcagaaatc ctttcggttg
    13621 actggacagt gggacgaaca ggcgtggtca cacctacagc gaatctaact cctgtgcaac
    13681 tagcggggac aaccgtgagt cgtgcaaccc tacataatgt ggattatatt gccgaaaaag
    13741 atatccgtat tggcgataca gtgattgtat ataaggcagg ggacattatt cctgctgtct
    13801 taaatgtcgt tatgagtaag cggaaccagc aagaagtcat gcttattcct aaactatgcc
    13861 catcttgtgg tagtgaatta gttcattttg aagatgaggt tgctttgcgt tgtattaatc
    13921 cgttgtgtcc tagtttgatt cagcgaagtt tggagcattt tgcaagtcgt gatgccatga
    13981 acattactgg gctgggacca gctattgtgg aaaaactatt tttagcgggg tttgttcatg
    14041 atgttgctga tatttaccag ttgaccaaag aagatttcat gcaattagat ggcatcaaag
    14101 aaaagtcagc tgataaattg ctcgctgcga ttgaggcttc taaatcaaat tcagctgaaa
    14161 aactgttatt tggtctagga attcgtcata ttggctctaa agttagtcgc ttaattttag
    14221 aggtatacgg agatatttct gctcttttaa ccgctaaaga agaggagatc gcaaggatag
    14281 atggccttgg ctcaacgatt gctcaatcac ttactcaata ctttgaacaa aaaacggctg
    14341 cgattttagt agacgagtta aagacagcag gtgtcaacat gcattactca ggtcaaaaag
    14401 ttaatagtga cgcagctctt tttggtctaa ctgttgtttt aactggcaaa ttaaatcagc
    14461 tgaaccgaaa tgaggccaaa gataaattag aggcattagg tgccaaagtt actggaagtg
    14521 tatctaagaa aacagattta gttattgcag gtagtgacgc tggttctaag ctagaaaaag
    14581 caaagagctt aggaattcgg attgaagatg aagattggct acgccagctt taagtgaggt
    14641 aatgttatga aaaaacaatt gagagcacgt ctcatttata atccaacgtc aggacaagaa
    14701 cttatgagaa aaagtgttcc tgaagtttta gacatattag aagggttcgg gtatgaaaca
    14761 tctgcctttc aaacaacagc acaaaagaac tctgctctaa atgaagcaag aagagcggca
    14821 aaggcaggtt ttgatttatt gattgctgct ggaggtgatg gcactattaa cgaagtggtc
    14881 aatggaattg ctcccttgaa aaagcgccct aaaatggcca ttattccaac aggtaccact
    14941 aatgattttg ctagagcgtt aaaagtacca agaggaaatc cgagccaggc agcaaaactt
    15001 atcggaaaaa atcagactat ccagatggat attggtagag ctaagaaaga tacttatttc
    15061 atcaatattg ctgcagcagg aagtttgacg gaattaactt acagtgtacc aagtcagtta
    15121 aaaacgatgt ttggatactt ggcttatctt gctaaaggag tagaactgct cccaagagtt
    15181 agcaatgtgc ctgttaaaat tacgcatgac aaaggcgtct ttgaaggtca agtttctatg
    15241 atttttgcag ctattaccaa ttctgttggg ggatttgaaa tgattgctcc tgatgcaaaa
    15301 ctagatgacg gtatgtttac gctcatttta ataaagacag caaatctttt tgaaattgta
    15361 catcttttgc gtttgatttt ggatggtggt aagcatatta cagatcgccg tgtcgaatac
    15421 attaagacca gtaaaatagt cattgaaccc caatgtggta agcgaatgat gattaattta
    15481 gatggcgagt acggaggaga tgctccaatt acattagaga acctaaaaaa tcatatcact
    15541 ttttttgcag atactgattt gatttctgat gacgctttag tcttagatca ggacgaattg
    15601 gaaattgagg aaatcgtaaa gaaatttgct catgaagtag aagacttaga acaagaatta
    15661 gaagaataat tagaagaata atacaatagt tattagctac tgacagttta gtcaaatgca
    15721 ctactattag aatctaagat ttttaaatca attgaggtag tgttttttga tgcactcaaa
    15781 gagtcaattt attcatatga ggggcccatt tgaggtctct cttttttgat catatgcaag
    15841 aaaataccat gttttagggg tgttattata ccctttttgg aatcttgttg cctttttgtt
    15901 ataataagag tgtaattcta tttttaaaaa gatcttaaca aagacagact cgtttatcaa
    15961 aaaggttagt attagtctaa gaaagcgtac tcagtctaaa gaaatctgtt gacattctta
    16021 attttaagga atagaatagc aaagtaaaaa aaatttaaag gagtattcta ctatgaatcc
    16081 tattttcgca ttggctttgg cctgttttgg tgtttctctt gccgaaggtt tcttgatggc
    16141 aaatcttttt aaagcagcat ctcgccaacc agaaatcatt ggtcaattac gttcattaat
    16201 gatcttgggt gttgccttta tcgaaggtac tttctttgtt acccttgtta tggccttcat
    16261 tcttaaataa cagcctattt gataatagaa aaggagggtg ttagatggaa gaagctaaaa
    16321 tacccatgct aaagcttggt ccaataacct ttaatttgac cctacttgct gtttgtattg
    16381 tcacaattgc tgttatcttt gcctttgttt tttgggcaag tcgccaaatg aaattgaaac
    16441 cagaagggaa gcaaactgct ttagaatatt taatcagttt tgtggatggt attggagaag
    16501 agcacttaga tcataatcta caaaaatctt attcgctgtt actctttacc atttttctct
    16561 ttgtggctgt cgctaataat ttagggttat ttactaagtt agagacagtt aatggctata
    16621 acctatggac ctcgccaaca gccaatctgg cttttgacct tgctctatct ctttttatca
    16681 ccttaatggt acacattgaa ggggttagac gtcgtggctt ggttgcccat ttgaaacgtt
    16741 tggctacacc gtggccaatg actccgatga atttattaga agagttcaca aatttcttat
    16801 cacttgccat taggttattc ggtaatatct ttgccgggga agttgttaca ggtttgattg
    16861 ttcaactggc caattatcga gtttattggt ggccgatcgc tttcctagtc aatatggcgt
    16921 ggacagcctt ttcagtcttt atttcctgca tacaggcttt tgttttcaca aaactaacag
    16981 cgacctatct aggaaagaaa gttaatgaat cagaagaata aggaaggaga acaaacgaat
    17041 gtcaatcaca tttggtgaac tcgttgggaa ttttattcta gtaacaggtt ctgtaatcgt
    17101 cttgttactc ttgatcaaaa aattcgcttg gggtgcaatt gaatcgattt tacagacacg
    17161 ctcacaacaa atctctcgag atattgatca ggctgagcaa tcacgtctaa gtgctcaaca
    17221 gttagaggca aaaagtcaag ctaacctaga tgctagtcgt tcacaagcaa gtaaaatcat
    17281 tagtgatgcc aaagaaattg gtcaattaca aggtgataaa ttggtggcag aagctactga
    17341 tgaagcaaaa cgcttgaaag aaaaagcgtt gacagatatt gaacaaagca aatcagacgc
    17401 tatttcagca gtcaaaacag aaatgtctga tttaacggtt cttttagcgg aaaaaattat
    17461 gggagccaat cttgataaga cggcgcaaag ccagcttatt gacagttatc ttgatgactt
    17521 aggagaagct taatgaccaa aaaagaacag gctcttatcg agcaatatgc aaaaagcctt
    17581 gttgaggtag caagtgaaca tcattctctt gatgccttac aagctgatgt gcttgcgatt
    17641 ttagagacgt ttgtaacaac taatcttgat caaagtctat caagtctagc tgttccgcat
    17701 gctgaaaaaa taaaattgct aaccttatta aagggaaata attctgttta tatgaataat
    17761 ttcttgaatc tcattttaca aaacgaacgt gaagcttatt tgtatcaaat gcttcaggct
    17821 gttttaaatg aaattgcaat agtttcaaat cagtatgatg tgactgttac ctcatcacta
    17881 cctttgactg aggagcaaaa aagccgtgtt cgagcagttg ttgcaaagaa atttgctgta
    17941 acagcgggtc gtttaattga aaaagtagat ccttcgctta ttggaggatt tattatcagc
    18001 gtcaataata aagtaattga taccagtatt cgtcgtcaat tgcaagcatt taaaatgaat
    18061 ttaaaataga aagtggtgtg acttttggca attaatgcac aagaaattag cgctttaatt
    18121 aaaaagcaaa ttgagaactt ccagccaaat ttcgatgtca cagaaactgg gatcgttacc
    18181 tatattggtg acggtattgc acgtgcccgt ggattagata atgccatgag tggtgaactt
    18241 cttgaatttg aaaatggtgc ctatgggatg gctcaaaacc ttgagtcaaa tgatgtgggt
    18301 attattattc ttggtgattt ttcagcaatc cgtgaaggag atgtggttaa gcgcaccggt
    18361 aaaatcatgg aagtaccagt tggtgaagct ctcattggac gtgtggtaaa cccacttgga
    18421 caaccagttg atggcttggg agatattgaa acaactggct ttagaccagt cgaaacgcca
    18481 gctcctggtg ttatgcagcg taaatccgtt tctgaaccct tacaaactgg attaaaagca
    18541 attgatgctt tggttccaat tggtcgtggg caacgtgagt tgattatcgg agaccgtcaa
    18601 acaggaaaaa catccgtagc aattgatgcg attttgaacc aaaaaggtca agacatgatt
    18661 tgtatctatg tggctattgg tcaaaaagaa tcaaccgttc gtacacaagt tgaaaccctt
    18721 cgccgttatg gtgccttgga ttatactatt gttgtgacag cgtcagcctc acaaccatca
    18781 ccattgctct ttatcgctcc ttatgcgggt gttgccatgg ctgaagaatt tatgtaccaa
    18841 ggcaagcatg tcttgattgt ctatgatgac ttatcaaaac aagcggtggc ttatcgtgaa
    18901 ttgtctctct tgcttcgtcg tccgccaggt cgtgaagctt acccagggga tgttttctac
    18961 ttgcatagcc gtcttttgga acgctctgca aaagtttctg atgacttagg tggaggttct
    19021 atcacagctc taccatttat cgaaacacag gccggagata tctctgcata tattgcgact
    19081 aacgttattt cgattacaga cggacaaatc ttcttgcaag agaacctctt taattcagga
    19141 attcgtccag cgattgatgc aggatcatct gtctcacgtg taggtggttc agctcaaatt
    19201 aaagcgatga aaaaggttgc tggtactctt cgtttggatt tggcttccta tcgtgaatta
    19261 gaagccttta cccaatttgg ttcggacctt gatgctgcaa cacaagcaaa acttaatcgt
    19321 ggtcgccgta cggttgaaat cttgaagcaa ccattgcata aaccgttacc tgttgaaaag
    19381 caagtcgtta ttctttatgc ccttactcat ggtttcttag atgatgttcc tgtagatgat
    19441 attttggctt ttgaagaagc tctttacgac tactttgacg ttcattacaa tgatttattt
    19501 gaaactatcc gtaccacaaa agaccttcct gaagaagctg cccttgatgc cgctattaaa
    19561 gcgtttaaag aacactcaaa ctttaagtca tagagggagg atactagtat ggcaggctct
    19621 ctaagtgaaa ttaaagctaa aattatttca actgagaaaa caagtaaaat cactagtgcc
    19681 atgcgtatgg tttcttctgc aaaacttgtt aaatctgagc aagcagctcg tgattttcaa
    19741 atttacgcct caaaaattcg ccagattact acagatttat tgaaatcaga attaaccata
    19801 ggatctgata atccgatgtt ggtgtctcgt cctgtcaaaa aaacaggcta tattgtcatc
    19861 acgtctgata aaggacttgt tggaggttac aattcaaaaa tcttgaaatc tgttatggat
    19921 atgattacag agtaccatgc tgatggtgac tatgaaatca tttctattgg tagtgttggt
    19981 tcagacttct tcaaagcaag agggatgaat gtggcttttg aacttcgtgg acttgcggat
    20041 caaccaagtt ttgaacaagt gagacaaatc atttcacaat ccgttgacat gtttgtcaat
    20101 gagatttttg atgagttata tgtctgttac aatcaccatg tgaatagctt aaccagccaa
    20161 gtccgtgttc aacagatgtt gccaatttct gacttggttg ctgatgaagc agcagaagaa
    20221 ggtgttactg ggtttgaatt ggaacctaat cgtcatgata ttttagatca attgttacct
    20281 caattcacag aaagtttaat ttatggggct atcattgatg ctaaaacggc tgaacatgca
    20341 gcaggtatga ctgccatgca gacagcaact gataacgcta agaatgtcat taacgatttg
    20401 accatccaat ataaccgagc tcgtcaagca gcaattacac aagaaatcac tgaaattgtt
    20461 gcaggagcaa atgcactaga ataaaaaatg acgctgacta gcgattaggt tattgtcagc
    20521 attcaatttt atcaatcgag ataaaatgac ttatgggact tttctattga aagactgctc
    20581 ttttcagtat aaaagaagtt agcaagacta actaagccct gactatcgaa tataaggaga
    20641 aatgaatgag ctcaggcaaa attgctcagg ttgttggtcc agtagtagac gttatgtttg
    20701 ctagcgggga caaacttcca gagattaata atgcattgat tgtttataaa gatagtgata
    20761 aaaagcaaaa aatcgtcctt gaagttgctc tggaacttgg tgacggtatg gtgcgaacaa
    20821 tcgctatgga atcaactgat gggcttacac gtgggttaga agttcttgac actggtcgtg
    20881 cgattagcgt accagtaggt aaagaaactt tgggacgcgt ctttaatgta cttggagaaa
    20941 ccattgattt ggaagaacca tttgcagaag atgttgaccg tcagccgatc cataaaaaag
    21001 caccatcgtt tgatgaatta tcaacatcat cagaaattct tgaaactggt atcaaggtaa
    21061 ttgaccttct tgccccttac cttaaaggtg gtaaagttgg actttttggt ggtgccggag
    21121 ttggtaagac tgtccttatc caagaattaa tccacaatat cgcccaagaa cacggaggta
    21181 tttcagtatt taccggtgtt ggtgagcgaa cacgtgaagg aaatgacctt tactgggaaa
    21241 tgaaagaatc aggcgttatt gaaaaaaccg ccatggtttt tggtcagatg aatgagccgc
    21301 ctggggcacg tatgcgtgta gcccttactg gtttaaccat tgctgagtat ttccgtgatg
    21361 tagaaggcca agatgttttg ctctttattg ataatatctt ccgtttcact caggcaggtt
    21421 cagaagtatc agccctctta ggccgtatgc cttctgctgt tggttaccaa ccaacccttg
    21481 ctactgaaat ggggcaattg caagaacgga ttacatcaac tcaaaaaggt tctgttacat
    21541 ctatccaagc gatttatgta ccagcagatg attatactga ccctgcgcca gcaacagcat
    21601 ttgctcactt ggattcaaca actaaccttg aacgtaaatt gactcaaatg ggtatttacc
    21661 ctgcggttga tccattagct tcaagttcac gtgctttatc acctgagatt gttggtgaag
    21721 agcactatgc tgtagcaaca gaagttcaac gtgtgcttca acgctaccgt gaattacaag
    21781 acatcatcgc tattttgggg atggatgaat tatcagatga agaaaaaaca ttggttggac
    21841 gtgcgcgtcg tatccagttc ttcctctcac aaaattttaa cgttgctgaa caatttaccg
    21901 gtcttcctgg ttcttacgtg ccagttgctg agacagttcg cggctttaaa gaaattcttg
    21961 aaggaaaata cgatcacctt ccagaagacg cctttcgttc agttggtcca atcgaggatg
    22021 tgataaaaaa agccgaaaaa atgggctttt agtgaggtga tgccatgaca caaatgactg
    22081 ttcaagtggt aacgccagat ggaatcaaat atgatcacca tgctaaatgt atttctgtaa
    22141 caacaccaga tggggaaatg gggattttac ctaaccacat caatttaatt gcacccttgc
    22201 aagttcatga aatgaaaatt cgccgaggtg gtgaagatga aaaagtggac tggattgcta
    22261 tcaatggtgg tattattgaa atcaaggata atgtggttac cgttgtcgct gattctgcag
    22321 aacgtgaccg tgatatcgat gtcagccgag cagagcgagc aaaactaaga gcagaacgtg
    22381 aaattgcaca ggctgaaacg acccacaaca ttgatgaagt ccgtcgtgcc aaggttgcct
    22441 tgcgccgcgc tttgaatcgt atcaacgtta gtaaaaaata agtggtgttg ataaaagaca
    22501 aggataagta agaaaggttt ttaacctatt attttgtttg ctgagtcttt ttaacatcag
    22561 tttctgagag tttgaccata ctaccttctc taaacacgtt attattgttg agaggagtta
    22621 tatgggggaa ctcttttttg tatccacgtt gttagtagaa actcagtaat gacgcttaat
    22681 gtattttcag gctatcaact tagtcagaga ggatgtcaat ttaattgata agttggacgg
    22741 atcaagatgg tatgttataa taatcctatg gaattattaa tgaagatcat tgccttttcg
    22801 tgtcatttat tttttattgg ccttagttac caattattga ttagtgtgat tgactggaca
    22861 aaatttagtc attatcatcc agaaaatctt ggccggctac gactttttgt ctttttatta
    22921 gctactgccc tagggtattt ggtgagccat tgtatgctgg aattgcttca aattagccag
    22981 acgctctttt ttgagttccg ctaatactgg aataaaagaa gtatggtata attttactac
    23041 gactaagaga tagataaggg agaaaattgt ggataaaata atcattgaag gtggtcaaac
    23101 acgcttagaa ggagaagttg ttattgaggg tgctaaaaac gcagttcttc ctttactggc
    23161 agcatctatt ttaccttcaa aaggaaaaac aattcttaga aacgttccta ttctatctga
    23221 tgtttttacc atgaataacg tggtacgtgg tttagatatt cgtgttgatt ttaatgaagc
    23281 agctaacgaa atcacagttg atgcctcagg acacatttta gatgaagccc cttacgagta
    23341 cgtgagccaa atgcgtgcct ctattgttgt tttaggacca attttggcac gtaatggcca
    23401 cgcaaaagta tcaatgcctg gaggctgtac gattggcagt aggcctatta atttgcactt
    23461 aaaaggatta gaggctatgg gggcaacgat tactcaaaaa ggtggagata ttactgctca
    23521 agcagatcga ctgcaaggtg ccatgattta tatggacttc ccatctgtag gagctaccca
    23581 aaacttgatg atggctgcca ctttagctga tggtgtgacc actattgaaa atgctgctcg
    23641 tgagcctgaa attgttgatt tagctcaatt tttgaataaa atgggagcta gaattcgtgg
    23701 tgctggaaca gagacgttaa cgataacagg cgtcacgcat ttacgaggcg tagaacatga
    23761 tgttgttcaa gatcgtatag aagccggtac atttatggtt gcagcggcga tgacttcagg
    23821 caatgttttg attagagatg ctgtttggga acataatcgt ccattgattt caaaattaat
    23881 ggaaatgggt gtttctgtaa cagaagaaga atacggtatt cgcgttcaag caaacacgcc
    23941 aaagctcaaa cctgtaacgg ttaaaacctt gcctcatcca ggttttccaa cagacatgca
    24001 agctcaattt acagctttaa tggcagtggt caatggagag tctactatgg ttgaaactgt
    24061 ctttgaaaat cgatttcaac atctggaaga aatgcgacgc atgggcttac aatctgaaat
    24121 ccttagggaa actgccatga ttcatggtgg aagacaactg caaggtgctc ctgtgatgtc
    24181 aacagattta cgtgccagtg ctgcccttat cttgacaggg attgttgctc aaggagttac
    24241 aatagttaat aatttggttc atttagatcg tggctactat caatttcatg aaaaattagc
    24301 aaagcttgga gctactatta gtcgtagcag tgaggtctag cttatgacaa atggtttaaa
    24361 atatgtctta gaacaaatgt tattactttt agtaattgct gccttggcgt gtcttttttt
    24421 agccattgga cttatgattg gttatagttt tatgggagat ggccatagtc catggcatat
    24481 tttatctatg gataagtggg cagagttagt gaataaattt actggaaagt aggccttgcc
    24541 tactttttat agcatctgag aggaagtatg ttaacaagga aaaaacgaaa aagggtgcaa
    24601 gagcaaaagg ttcctaaaag agctaatgcc ttacttacta agtcgacacg acagtatcga
    24661 aatcgctatc aaacggacaa tgcttatcgt aactttaagc cagcaggttg gcaccgattg
    24721 caccacttaa aaggaagtta tgatcacgcg gttgatagag ggcatttgct aggttatgct
    24781 ttagttggtg gactgaaagg ttttgatgct tctaccggta atcctgataa tattgccact
    24841 caactaagtt gggctaatca agcaaataaa ccctacgcga caggtcagaa ttactatgaa
    24901 ggtttagtac gtcgtgcttt agataagggg catcgcgtcc gctaccgtgt caccctactt
    24961 tatgatggtg ataatctact agccagcggt agccatttgg aggctaaatc ctctgatgac
    25021 agcttgactt ttaacgtgtt tgttccaaat gtccaaccag gattgaccgt tgactatcgg
    25081 acgggacaaa tagctatcaa tctctaagcg aaaagtcact gatttaagat tgtcactaag
    25141 cacttttttt gatagaatag aactaattga ataagtgtct atgagactag tactaataga
    25201 gaaattaaca gggagtgagg gccgtgactg gaagccttct taagggaact attaggaatt
    25261 cactcagcta aagacaatta attaaggtct gataacatca gataaaaacg gatggtaccg
    25321 cgtgtcaacg ctccgcttat caagtggagg agtggcatgc ttttttcatc gccaaaagaa
    25381 gggaaaacta tggatttaca agcacaatta gaggaattaa agacaaaaac attggagacc
    25441 atacagtctt tgacgggtaa tcataccaaa gaactgcaag atttgcgcgt ggctgttctt
    25501 gggaaaaagg gatctttgac agaattacta aaggggctaa aagacttgtc taatgacttg
    25561 cgtcctgtgg ttggtaaaca ggtgaacgaa gttcgtgact tattgacaaa agcctttgaa
    25621 gaacaggcta aaattgtaga agctgctaaa attcaggccc aacttgatgc tgaaagcatt
    25681 gatgtgactt taccgggtcg tcaaatgact ctggggcatc gtcatgtgtt aacacaaacc
    25741 agtgaagaaa tcgaagatat tttcttagga atgggttttc agattgttga tggctttgag
    25801 gtggaaaaag attattacaa ctttgagcgc atgaatttgc caaaggatca ccctgcccgt
    25861 gacatgcaag atacgtttta tatcacagaa gaaatcttgt tacgaactca caccagtcct
    25921 gtgcaggccc gtactcttga tcaacatgat ttttcaaaag ggcctttaaa aatggtttct
    25981 ccaggtcgtg ttttccgtcg tgatactgat gacgctaccc actcacatca attccatcaa
    26041 attgaaggtt tggttgtggg caaaaatatt tccatgggag acctcaaagg gactcttgaa
    26101 atgatcatca agaagatgtt cggtgaagaa cgtagcattc gtttgcgccc gtcatatttc
    26161 ccgttcacag aaccatctgt tgaagtggat gtttcttgct ttaaatgtgg tgggaaaggc
    26221 tgtaatgtct gcaagaaaac aggatggatt gaaattcttg gtgctggtat ggttcaccca
    26281 agtgtcttgg aaatgtcagg tgttgatgca aaagagtatt caggctttgc ctttggttta
    26341 ggtcaagagc ggattgccat gttgcgttat ggcattaatg acattcgtgg tttctatcaa
    26401 ggcgaccaac gtttctctga acaatttaac taaaacgagt cgtttgaaga cctctgtcag
    26461 ctattttatc taagattgag tgaaagttga taggtaatga taataggtta attgtctaag
    26521 gagaaagtcc ctctcgcttc aacgtcataa gggttttgac ttggaactta aaatacgaaa
    26581 ggaaatgact caaatcacgg cttgagagct ttctctagcc gagtgatttg ggcactaaaa
    26641 ttatgttagt atcttataaa tggttaaaag aattagtaga tatcgatgtg acaccagcag
    26701 cacttgctga gaaaatgtcg acaacgggta tcgaggtaga aggaattgaa gtccctgcag
    26761 aaggtttatc aaaactggtt gtggggcatg tgctttcttg tgaagatgtg ccagagacac
    26821 atttgcattt gtgtcaggta gatacaggtg atgaaacgcc acgtcaaatt gtgtgtggtg
    26881 caccaaatgt gaaagcaggg attaaggtta tcgtggctgt gccaggtgct cgtattgcgg
    26941 ataactataa aatcaaaaaa ggcaaaatcc gcggcatgga atctcttggt atgatttgtt
    27001 ccttgcaaga acttggtttg tcagatagta tcattccaaa agaattttca gacggtattc
    27061 aaatcttgcc agaggaggct gtgccaggtg atgctatttt taaatacctg gacttggacg
    27121 atcatatcat tgaattgtcc attacaccta accgtgctga tgcgctttct atgcgaggtg
    27181 tggcacatga agtcgcagct atttatggca agtcggtgtc attcccagaa aaaaatctac
    27241 aagaatctga taaggcaact tcagaagcca ttgaagtggc cattgcctct gataacgttc
    27301 taacttacgc tagccgtgtc gttgaaaatg tcaaagttaa gccgagtcca caatggttgc
    27361 aaaacctttt aatgaatgct ggtattcgtc ctattaataa tgtggttgat gtgaccaact
    27421 atgtactctt gtactttggt caacctatac atgcttttga ttatgataaa tttgaagacc
    27481 ataagattgt ggcgcgtgcg gctcgtcaag gggaaagttt agtcacactt gatggtgaaa
    27541 aacgggaatt gaccactgag gatcttgtta ttaccgtggc tgacaaacca gttgctttag
    27601 caggtgttat ggggggtcaa gccactgaaa ttgatgccaa ctctcagacg gttgttcttg
    27661 aagccgctgt tttcgatggc aaatcgattc gtaaaacgag tggtcgttta aaccttcgtt
    27721 cggaatcatc ttcacgcttt gaaaaagggg ttaactatgc aactgtttta gaagcgcttg
    27781 actttgcagc ggctatgtta caagaattag cagaaggtca agtcttatca gaccatgttc
    27841 aagctggtca attgccaaca gaacctgttg aagtctcaac tagccttgac tatgtgaatg
    27901 ttcgtttagg aacagagttc acttttgaag acattcaaac tgtttttgat caacttggtt
    27961 ttggactgac aggagatgaa acaagcttca cggtagctgt tccgcgccgt cgttgggata
    28021 ttagcatccc agctgacttg gtggaagaaa ttgcgcgtat ctatggttat gataagttgc
    28081 cgacaacctt accagaggca gggggaacgg ctgcagaatt aacgccaaca caggttcttc
    28141 gtcgtaaagt ccgtggctta gcggaaggat tgggcttgac tgaaatcatt tcgtatgctt
    28201 tgacaacacc agagaaagct atcgagtttg cagtggcacc aagtcaccta acagaactca
    28261 tgtggccaat gtctgtggaa cgttcagcgc ttcgtcaaaa tatggtttca gggatgttag
    28321 atacggtagc ttataatgtg gctcgtaaac aaagtaactt ggctctttat gaaattggaa
    28381 aaatctttga acaagaagct aatccaaaag aagaccttcc taatgaagtg aaccattttg
    28441 cttttgctat ttgtggctta gtggcacaaa aagatttcca aacccaagct caggcagtgg
    28501 atttttacca tgctaaaggt gtcttggata ctttatttgc aaaccttaac ctcaaggttc
    28561 aatatgtgcc aaccaaagac ctagcaaaca tgcacccagg acggacagcg cttatcctat
    28621 tagatgagca agtgattgga tttgttggtc aagttcatcc aggaacagca aaggcttata
    28681 gtattccaga aacctatgtg gcagaattgg atatggctgc tttagaagca gcgttgccaa
    28741 gtgatcaaac ttttgcggaa atcacaaaac tccctgctat gacacgtgat gttgccttgt
    28801 tacttgaccg tgaggtgagt catcaggcca ttgtaacagc tattgaatca gcaggtgtaa
    28861 aacgcttgac tagcattaaa ctctttgacg tctatgaagg agcaaccatt caggctggca
    28921 aaaaatcaat ggcttatagc cttactttcc aaaatccaaa tgacaattta acggatgaag
    28981 aagttgccaa atacatggag aaaatcacca aagcattgac agaacaagtc ggtgctgaag
    29041 tacgctaaga aaaaaactgg gcctctaagg ctccgttttt ttctgttata atagaggaaa
    29101 aaagaactcc agttcaaatg attggagaaa aacatcagaa ggtggaggaa aatcagaatg
    29161 tatcaaacaa aaataacagg caaccgcctt taccacacgg tttcgaaagg ctacggagat
    29221 agtgtaacct tatttggaaa aactgatcaa ggggaaaccc ctatgagttt actggttatt
    29281 gccttgtctt cttgtgtgac tatgtgtgtg cagggttttt accatcgtca atttcagcaa
    29341 gacacacttg ctgtttctgt tgaggctagt tatgaggaag aagtttttga actacttgtt
    29401 aggattgatg atgttttaga tgacaaaaag aaagctgatt tattggctta cattggaact
    29461 tattgtcgtg tgaaacaact cctcaaacct gaagttacgg tgaccattac gttggaagga
    29521 ctgtctcatg tctgatgcta gtttgaaaac ttaccaaaaa caatgggctt atcaaaagta
    29581 ttgggtcatg gcacactcac aacagcatta caatgcttta agagaattgt ttaaaggaaa
    29641 tcagtggtca gaagaaaagg tgttgacttt tcattgtttg attgaagaag cgcaagccat
    29701 tcctcccaca gtaaaaagct tacgaacagc atatcagcat gtttgggggt attttaaaaa
    29761 ggtagcgagt caggaagaaa aagaccattt caaagatttg gatgctcagt tggaaactaa
    29821 atctgaggag atgctatgct ttttacaaga gatgactgct cattatcagc cctcttatct
    29881 gctatcttgc cgtttgatta ccaaaggtcc ttaaatgcta aacagaaaag tagggatttc
    29941 tgggaagtta tgctaagcta gtgatataaa taagggggaa tgagagatgt ttttagcgct
    30001 taatgaaatg aaacaatcca aattgcggta tggtttgatt gctggtttgc tatgtttggt
    30061 tgcctatttg atgttctttt tgtcaggatt ggcctttggt ttgatgcagg agaaccgctc
    30121 ggcggttgat ctttggaaag ctgacagtgt tttactagcc aaggatgctg acgctacctt
    30181 gaccttatca caggtgtcca gagctcaaga aaatcaaata acagcagaca aggtagctcc
    30241 tcttgctcaa ctcaataccg tggcgtggtc agttaaaaat cctaaggatg ccgacaaagt
    30301 taaggttagc cttttcggga ttgattctaa tagctttatt cgtcctaaca ttgtaaaagg
    30361 tcgattattt aagactaaca aagaggttgt tttggatcaa agccttgcaa aagaggaagc
    30421 ttttgcgatt ggcaaggact tttacacatc gagttctagt caagcattaa ctatcgttgg
    30481 ttatactcaa aatgctagat ttagtgttgc accagtggtt tatatgaatt tggaagcttt
    30541 tgaaacatta aaatatggag aaccactacc aaaagataag caagttgtta atgcttttat
    30601 cactaaagga agtttaacag attatcctaa aaaagacttc caaaaattag atattaaaac
    30661 ctttattact aaattacctg gttatagcgc tcaactttta acttttggct ttatgattag
    30721 ttttcttgtc attatttcag ctattattat tggtattttt atgtatattt tgactattca
    30781 aaaggcacct atttttggga ttatgaaagc gcaaggtatc gggaatataa cgattgcaca
    30841 agcagttctg ctgcaaacct tcttgttaag tgctttagga agcggtttag ggttattggg
    30901 aacttggttg acgtctttag tgctccctga agcagttccc ttccaaagta attggctagt
    30961 ttacttagcg atattagtca gtatggtttg ttttgctttg ttaggaacct tattttctgt
    31021 ttttagcatt gtacgaattg atcctttgaa agcaattgga taggaggtag tgatgtcggt
    31081 tttaacattt aaacaagtga ccaaaacatt tcaagatggt catcacgaaa tcaacgcatt
    31141 aaaggcaact gacttttcca ttgaagctgg agaatttgtg gctattattg gaccatcagg
    31201 ttctggaaaa tcaacctttt tgaccattgc tggtggctta cagaccccaa gctctggtca
    31261 gctaatcatt gatggcactg attataccca tttatcagaa aaagagcgct cacgcttgcg
    31321 cttcaaatcc gttggtttta tcttacaagc ttccaatctg ataccttttt taacggtcca
    31381 gcagcagttg gaattggtcg atcatttgac aggaagcaaa gaaaaagcca aagccaatca
    31441 gttatttgac gatttaggca ttgcagggct aaaacatcag ttacctcaag aattgtccgg
    31501 cggagaaagg caaagagcgg ctattgcccg tgctctttac catgatccag cactgatatt
    31561 ggcagatgaa cctactgcaa gtttggatac tgaaaaagcc tatgaagtgg tcaaactgtt
    31621 ggctaaggaa agtaaagaaa aaaacaaggc cattattatg gtcactcatg atgatcggat
    31681 gctagaatat tgtgacaaag tctatcggat gcaagatgga gagttacgtc aagagagata
    31741 gtagactggt aagagtttat gatattagaa gaaaaaacca aacaagcaca gcacttgtct
    31801 ggtttttttc taagtgtgac tattatcaat acgtcaccat ttccctaaag cttactatac
    31861 gggatgctaa aggtatcacc atgctcaaag tcgccatatt ggtaacctcg gtcaaaccaa
    31921 cgttggcgtt gcttagaagt tccatgggta aaactatcag gaacggctct gccataggtt
    31981 tcttcttgca gagtatcatc cccaactgcg tgagctgctg ccattgcctc ctcaatgtct
    32041 cctttttcca aaaggccttg cccttgaaca taattagccc aggcaccagc atagtaatca
    32101 gcttgtaatt ccaacttgac gttgagctga ttggctttag cctttgattt tccttgtcta
    32161 gcgctagcgt aattatccat aattcccaat tcattttgga tgtggtggcc aacttcatga
    32221 gcaatcacat aggccatagc gaaatcacct tttgcgccgt acttggttga tagttcatta
    32281 taaaaagaaa tatctaaata cactttttga tcgcctgggc aatagaaagg accagaagag
    32341 gcttgccccc tgccacaagc ggtttgagtt gctccagtat atagaactaa tgttggttta
    32401 tgataagtta accctttctc acgaaatgtc ttagtccaat agtcctcggt agaggcgaag
    32461 accttactga caaaagaaac ctgttcttga ctagccttgt caccatttgt acgcgttact
    32521 tggcttgatt gataggcatt gttgttggta gaagaaggct tgcctcctaa aacaccagat
    32581 aggccacctc ctcccataac taggagaagg agaagaataa ccagcttggt tttccaacct
    32641 cctcgtgaaa agagtaattg aagcaggaga ccgcccccta ggccgccgcc cccaaaagaa
    32701 ccagacgatt gaccacgtct atcttcaacc tgttgacttt ctctcaaatc atctgttttc
    32761 ataagtttct cccatctatt tcttgatttt attataaaat aattctatta gaattgctat
    32821 ttttatgatg agattataac taaaaatagg aaaagcaata ggtatttgct ataatataac
    32881 aagggtagat tcagtttgta taaaggagtc atatgaaatt aatttacaca gagatgagtt
    32941 actcgatgac agagattttg gtgaatgaag cacgaaaagc tgctgaccaa ggttatcgag
    33001 tgttctatat tgctccaaat tctctttcat ttgaaaagga aagagaagtc ttaaccttat
    33061 tgcctgaacg agggactttt tcgataatag tcacccggtt cgttcaaatg tcaaggtatt
    33121 ttacagttga gagctctcct tctaagcaac atctagatga cacgactttg gctatgattt
    33181 tttatcgggc cttgatgcaa ttaaaaccag aagatttgcc gagttatggt cgtttgcaaa
    33241 ataattcggt ttttattgaa caactagttg agttatataa ggaattaaaa aacgcacaat
    33301 taagcgtaca tgatttaaca ggattagacc atcctcaaaa acaagaagat cttattaaaa
    33361 ttattgagct tgcagagacg atcatgattc agcaagatta taatcaagat agtcctctac
    33421 aatcttttgc aagagcaatt aagttaggac ttttaaataa ccaactatca aaaacagttg
    33481 ttgttattga tggtttttca cgtttttcag ctgaagagga ttatttatta tcacttttaa
    33541 ataacaactg tcaagaggtc atcattggca gttatgtgag tcaaaaagct tatcaaaaat
    33601 cttttattaa gggaaatatc tatgaggcta gccttcattt tttgcaggat ttggctcaaa
    33661 aataccatat caagccggta tttgcgacct ctaatcaagt gtttaaacca gccttttcac
    33721 ggctaacaca attatttgaa gcaactcatg atttttcaca agtagactgg caactccaaa
    33781 agaatgatct tgatcacttt agcctttggc aatgtcatca tcaaaaagag gaaattgaac
    33841 atgtagcaaa atccattcgg caaaagctat atgaaggtta ccgttataag gatatcttag
    33901 tgttgctagg agatatggat gcttatcaat tacaaattgg gcctatcttt gataagtttg
    33961 aaatccccta ctatttagga aaagcagagc ctatggctgc ccatccatta gtccaattta
    34021 tagaatcgct cgaacgaagt cagcgctaca attggcgtcg tgaagacatt ttaaacatgt
    34081 taaaatcagg actttttggt tgttttgatg atagtgatat tgatcgcttt gaggaatata
    34141 ctcagtttgc agatattaaa gggtttacta aattttcaaa gccttttacc attaactctt
    34201 ctaggcagta tcctcttgac tttttaaatg aaatgagaca agacatcgtt ttacctttgc
    34261 aagaattgtt taagagtaaa aaacaacttg gtgcttcact tgttgacaaa ttaatacttt
    34321 ttttaaaaaa gattagatta gctgagaata tgcaaggttt agcacagtcc caattagagg
    34381 tggaaaaaaa cgaagaagtt tggaaaaggt ttacagatat tttgacttct tttcatcata
    34441 tctttggcca agaaaaatta cggctatcag attgccttgc tttaatcaaa acgggaatga
    34501 aatcagctca gtatcgtgtt gttccagcga cattagatgt tgtcactatt aaatcttatg
    34561 accttgttca accacattca aaacctttcg tttatgcaat tggtctaact caatcacatt
    34621 ttcctaagca aattcaccat tcaggactac tttctgatca agagcgtgct agaattaatg
    34681 aaataagaaa ttatcgtcat tttgatattg ctagtgccga aaatagtaaa aaaaaccatc
    34741 aaactgcgtt atctctgttt aatgctgcta ctaaagagtt agttcttagt gttccaacgg
    34801 taatcaacga gacattcgat gatctatctc cttatcttaa agaattaata agctttgggc
    34861 tacctctttt ggataaaggc aaaaactatc tatcttatga taatagcgat attggtaact
    34921 ataaagctct cttgtcacaa attattgcta ttaaccgaca agatcttata gaaatgtcag
    34981 atcaagataa gatgttttgg actgttgtct tacgttatct caggaaacag ttaagaaagc
    35041 aacagctaga gttacctact tcagattatc gtttatcaac aaagcctttg tctaaagaag
    35101 ttatcgaggt atgttttcca aagagaatcc ctttaaagct atctgcaact gctttaaccg
    35161 ttttttataa taatcagtac aactattttt tgaaatatgt tttgaattta aacaaaacag
    35221 aatccattca tccagattcc agaattcatg gtcaatactt gcatcgtgtc tttgagcggt
    35281 taatgaaaga tcacacgcaa gaaccgtttg ataataaatt aaaacaagca atctaccata
    35341 ccaatcaaga aagttttttt cagcaggttt accaagataa tgccgaggct gagtacagtt
    35401 tagctatact agaagatatt gttagatcaa cagcacctat cttgcaactt aaccaaaaca
    35461 tacaggtcat tgatcaagaa aagaactttc atctggatat gggaaatgag atattagtcc
    35521 acgggatcat tgatcgtatt gaccagctga gcgacggtag cttgggcatt gttgactata
    35581 aatcaagcgc gaatcaattt gatattggga ccttttataa tgggttgagt ccacaactag
    35641 tgacttacct cgcagcctta aaacagatca caccgcacga tataaaccaa ttatttgggg
    35701 ctatgtacct tcatttgcaa gatcctaaat tggatctagt aacatttaaa caaattgata
    35761 acacattagt ggagagtatc tataaagcgt tgacttataa aggtattttt tcagaagtcg
    35821 aaaaagagca tctatctact ggtgcttacc aaaccaaaaa tgctctttat tccaatgacg
    35881 aattggaaac acttttaaat tataacaagt acctctatct taaagctgct aaacacatta
    35941 aaaagggaca ttttttgatt aatccttata caagcgatgg taagacagtt caaggagatc
    36001 aattaaaagc cattacccgt tttgaagcag atcttgacat gggacaggca aggcgactag
    36061 tgactctccc tgctaaggag aaaaaagagt gctttttaac attaatgaga aaggagagcc
    36121 acttgtgatt tcttttgccc catttttaag ccccgaagct attaaacatt tacaagaaaa
    36181 cgaaaggtac agtgatcagt ctcaaaaacg cacagctcaa caaattgaag caatttatac
    36241 tagtggccaa aatatacttg tatcagcttc tgctggttca ggaaaaacct ttgtaatggt
    36301 cgaacgcata cttgataaaa ttttgagagg tgtttcaatt gatcggcttt ttatctcaac
    36361 ctttactgtt aaagcagcta cagaactgcg tgaacggatt gaaaacaaat tatactcaca
    36421 aattgctcaa actacagatt ttcaaatgaa agtttattta acagaacaat tgcaatctct
    36481 ttgtcaagct gatattggta ctatggatgc ttttgcacag aaagtagtaa gtcgctatgg
    36541 ttatagcatt ggcatttcat cccaatttcg tatcatgcag gataaagcag aacaagatgt
    36601 tttaaagcaa gaggtgttta gcaaactctt tagtgagttt atgaatcaaa aagaggcacc
    36661 ggtgtttagg gctcttgtga aaaatttttc tggtaactgt aaagacactt cagcttttag
    36721 agagttagtt tatacttgtt attcttttag ccaatcgaca gaaaatccaa aaatatggtt
    36781 gcaagaaaat tttctaagcg ctgctaaaac ttaccaaaga cttgaagata tcccggatca
    36841 tgatattgaa ctcttacttt tggcaatgca agacactgca aatcagctaa gagatgtgac
    36901 tgatatggaa gattatgggc agctgactaa ggcaggtagc cgatctgcta aatacactaa
    36961 acacttaacg atcatagaaa agttgtctga ttgggtgcgt gattttaaat gtttgtatgg
    37021 aaaagccgga ttggatcggt tgatcagaga tgtgacagac cttataccat ctgggaatga
    37081 tgttacagtc tcgaaggtaa aataccctgt ttttaagacc ttgcatcaaa aattaaaaca
    37141 atttaggcat ttagaaacaa ttttaatgta tcagaaagac tgttttccct tattggaaca
    37201 gttacaagat tttgtgcttg cgttttcaga agcttattta gctgtcaaaa tacaagaaag
    37261 cgcttttgaa ttttcagata ttgcacactt tgcaatcaaa attttagagg aaaatacgga
    37321 tattcgccaa tcctatcagc aacactatca tgaggtgatg gttgatgaat atcaagataa
    37381 caatcatatg caagagcgac tcctgacctt actatcgaac ggtcataatc gctttatggt
    37441 aggagatatc aaacaatcga tctatcgatt tcggcaagcc gatcctcaga tttttaatca
    37501 aaagtttaga gactatcaaa aaaaacctga gcaggggaaa gtgattttac tcaaagaaaa
    37561 ctttcgtagc caatcagagg tgttaaatgt cagcaacgct gtttttagtc acttaatgga
    37621 cgaatcagta ggaaacgtct tatatgatga gcaacatcag ttaatagcag gtagtcatgc
    37681 tcaaacagtc ccctatctag accgtcgtgc tcagttattg ctatataata gcgataaaga
    37741 tgatggcaac gccccttcag atagtgaggg tatttcattt agtgaggtta caattgttgc
    37801 caaagaaatt attaagcttc acaatgataa gggtgtccct tttgaagaca ttacgttact
    37861 cgtttcttca agaacaagaa atgatatcat ttctcataca ttcaatcaat atggtattcc
    37921 tatagtaaca gatggtgggc agcaaaacta tcttaaatct gttgaagtga tggttatgtt
    37981 agatacatta cgcaccatta acaacccaag aaatgattat gcccttgtgg ctttactgcg
    38041 ctcaccgatg tttgcccttg atgaggatga tttagcaaga atagcacttc aaaaagacaa
    38101 tgagctagat aaagattgcc tatatgacaa gatacaaagg gctgtgattg gaagaggtgc
    38161 tcatcctgaa ttgattcacg ataccttgct tggcaagtta aatgtttttt taaagacgtt
    38221 gaaaagctgg cgtcgatacg ctaagctagg gtcgttgtat gacttgattt ggaaaatttt
    38281 taatgatcgt ttttattttg attttgtagc tagtcaagca aaagcagaac aagcacaagc
    38341 taatctatac gcattagctc tacgtgctaa tcagtttgaa aaatcgggct ataaagggct
    38401 ataccgtttt attaaaatga ttgataaggt acttgagacg caaaatgact tagctgatgt
    38461 ggaagtggct gctcctaaac aagctgttaa tttaatgacc attcacaagt ctaaaggttt
    38521 acaatttccg tatgtattta tccttaattg tgacaagcgc ttctcaatga cagatattca
    38581 taaatcattt attctgaatc ggcagcacgg tatcggtatc aagtaccttg cagatatcaa
    38641 aggtttactt ggtgaaacaa cactcaattc tgttaaagta agcatggaaa ccttacctta
    38701 tcaattgaac aaacaagagt tgcgcttagc aactttatca gaacaaatgc gcttactgta
    38761 tgttgctatg acacgagctg aaaaaaaagt ttattttatt ggtaaagcta gtaagagcaa
    38821 aagtcaagaa atcacagatc ctaaaaagtt aggcaaactt ttgccgctgg ctttacgaga
    38881 acagttattg acattccaag attggctatt agcaatagca gatatatttt caactgaaga
    38941 tctttatttt gatgttcgct ttattgaaga tagtgatttg acacaagagt cagtcggacg
    39001 acttcaaaca ccacagttat taaatccaga tgatcttaaa gataatcgtc aatcagaaac
    39061 aattgcacgg gctttagata tgttagaagc agtgtctcaa ttgaatgcca attatgaagc
    39121 agctattcat ttgccaacag ttcgaacgcc tagccaactt aaggcagctt acgagccttt
    39181 attagaaccc attggtgtag atattataga gaaatcttct cgatcgctat ctgattttac
    39241 tttgccacat ttttcaaaaa aagcaaaagt tgaagcaagt catattggat cagctcttca
    39301 tcagttgatg caggtgctcc ctttgtcaaa accgataaat caacaaacgc ttttagacgc
    39361 tttaagagga attgatagta acgaagaggt aaaaacagct cttgatctca aaaaaataga
    39421 gtcgttcttt tgtgatacaa gcctaggcca attttttcag acttaccaaa aacacttgta
    39481 tcgagaagca ccatttgcta ttttaaaagt tgaccctatc agtcaagaag aatatgtcct
    39541 acgtggtatt atagatgcct actttttgtt tgatgatcat attgtattag tggactataa
    39601 aacagataaa tacaagcagc ccattgagtt aaaaaagcgt taccaacaac agttggagtt
    39661 atatgcagaa gctctcactc aaacgtataa acttcctgtg actaagcgct atcttgtttt
    39721 aatgggaggt ggaaagccag aaattgtcga agtttaaggt tgttgtgaca caagggtatt
    39781 ttgcaaatga taatagtaga gttgaggatt ttacgaaata cttgaaaagc tattgacctt
    39841 tgaataataa tacaatataa taagttttat tagcgacaaa aaggaataaa tatactatga
    39901 attttaaaaa aataagattt ggttttttgc tttgcctcct actttatcct ttagcagctt
    39961 gtaacaagtc tgaacaactt aatcactacg aaagaattaa aaaaacaaga aaattagtcg
    40021 ttgctgtaag ccctgattat gctccttttg aatttaaagc tttagttaat ggaaaagata
    40081 ctattgttgg agcagatgtt cacttagctc aggctattgc tgatgaatta gacgttgatc
    40141 ttgagctttc accaatgagt tttgataatg ttttgtctag tttacagact ggtaaagctg
    40201 atcttgctat ttcaggaatc tcacatacta aagaaagagc taaagtatat gatttttcaa
    40261 ttccttacta tcaggcagaa aatgctatag tgatgagagc atctgatgct aaagtgacca
    40321 aaaatattag tgacctaaac ggtaagaaag tagccgctca aaaaggtagt atcgaggaag
    40381 gtttagttaa aatacaatta ccaaaggcca atctgatttc tttgactgct atgggagaag
    40441 ccattaatga actaaaagca ggacaagtct atgcagttac cttagaagca cctgtagctg
    40501 ctggtttttt agcccaacat aaggatctgg ctttagcacc ctttagctta aaaaccagtg
    40561 atggagatgc caaagcagtg gcccttccta aaaatagtgg tgacttaacc aaagccgtta
    40621 ataaggttat tgctaagtta gatgagcaag aacggtacaa gtcatttatt gcagagacaa
    40681 tagcactaac gaaaaatact atgaagtaat aaggttaata aaaactttat tagtatccgt
    40741 tggaaaagtg tttggaataa acaataaaag aggtttgact ttttttaaaa aataatgtaa
    40801 tataattggg aacgtgcaaa tgttacaata tcttgaggag gtgaaacaca tgtcaaaaac
    40861 agtagtacgt aagaatgaat ctcttgacga tgctcttcgt cgcttcaaac gttctgttac
    40921 taaagctggt actcttcaag aatcacgtaa acgtgaattc tacgaaaaac cttctgtaaa
    40981 acgtaaacgt aaatcagaag cagctcgcaa acgtaaaaaa ttctaatggt aaaaaataaa
    41041 aacagttctc acaattagaa ctgtttttat tttttatcca gaagaagcaa gggagttttt
    41101 ttgatatcaa aaaaagcagt tagacatgcc taactacttt atcaaaaatc gccttatttt
    41161 tgagccaaca aatcacggat ttctgtcaat aattcttctt gagtaggagc tgcagcttct
    41221 ttttcttttt taggcatagc tttttcagcg gcttttacaa caaagaaaag actggtaccg
    41281 atgataagaa aattaataac ggctcctaaa aagctaccat atttaacacc attccatgac
    41341 aattgagtga tgttttcaac atttgcagct ttcaaagctg ggtttaaaat aagcggtgtg
    41401 ataatatcgt tcacaaaaga agtgacaata gcaccaaaag ctcccccgat gataactgct
    41461 acagcaagtt caataatgtt tcctctaaac aaaaatgctt ttaattcttt aaccattaaa
    41521 cattccccct ttttaatatc tctaagttaa gcatagcata attagtaaac aaaatccaat
    41581 ggaatcactt cagtttttaa atttacaaaa aagagtttcg gtggtataat aaaacgtaaa
    41641 actaaaatgg gatttttatg gggaggtgac gatttggcaa ttgacaaaga aatgatttcc
    41701 caagtaaaaa atagcgttaa tattgtcgat gtcattggag aagtggtcaa actttcccga
    41761 tcagggcggc attatctcgg gctttgccca tttcataagg aaaagacacc ctcttttaat
    41821 gttgttgaag acagacaatt ttttcactgc tttggctgtg gaaaatcagg ggatgttttt
    41881 aaatttattg aggaataccg ccaagtcccc ttcttagaaa gtgttcagat tattgccgat
    41941 aagactggta tgtcgcttaa tataccgcca agtcaggcag tacttgctag ccaacacaag
    42001 caccctaatc acgctttgat gacacttcat gaggatgctg ctaaatttta ccatgcagtt
    42061 ttgatgacca ctactattgg taaagaagct aggaagtacc tttaccagag aggcttggat
    42121 gaccaattaa ttgagcattt caatattggt ttagccccag atgagtcaga ttatctttat
    42181 caagctcttt ctaaaaaata cgaggaaggt caattggttg cttcaggatt gtttcacttg
    42241 tccgatcaat ccaataccat ttacgacgcc tttcgaaatc gtatcatgtt tcccttatca
    42301 gatgaccgag ggcatattat tgccttttca ggacgtatct ggacggcagc tgatatggaa
    42361 aagagacagg caaagtataa aaattcaaga ggaacagttc tttttaacaa atcttatgaa
    42421 ttgtatcatc tggacaaggc aaggcctgtt attgccaaaa cccatgaagt gtttctaatg
    42481 gaagggttta tggacgtgat tgccgcttac cgttctggct atgaaaatgc tgttgcttca
    42541 atggggacgg cactgactca agaacatgtc aatcacctta agcaagtcac taaaaaagtt
    42601 gttttgattt atgatggtga cgatgctgga caacatgcta ttgcaaaatc actagaattg
    42661 cttaaagatt ttgttgtcga aattgtcaga atccccaata aaatggatcc tgacgaattt
    42721 gtacaacggc attccccaga agcatttgca gatttgctta agcagtcacg gatcagtagt
    42781 gttgaatttt ttattgatta cctaaaacct actaatgtag acaatttgca atcacaaatt
    42841 gtttatgtgg agaaaatggc accattgatt gctcaatcac catccatcac agctcaacat
    42901 tcgtatatta acaagattgc tgatttgttg ccaaactttg actattttca agtagaacaa
    42961 tcagtaaatg cattaaggat tcaagatagg caaaagcgtc aaggtcaaat agctcaagcc
    43021 gtcagcaatc ttgtgacctt accaatgcca aaaagtttga cagctattgc taagacagaa
    43081 agtcatctca tgcatcggct cttacatcat gactatttat taaatgaatt tcgacatcgt
    43141 gatgattttt attttgatac ctctacctta gaattacttt atcaacggct gaagcaacaa
    43201 ggacacatta catcttatga tttgtcagag atgtcagagg aagttaaccg tgcttattac
    43261 aatgttttag aagaaaacct tcccaaagaa gtagctcttg gtgagattga tgatatttta
    43321 tccaaacgtg ccaaactttt agcagagcgc gatcttcaca aacaagggaa aaaagttaga
    43381 gaatctagta acaaaggcga tcatcaagcg gctctagaag tactagaaca ttttattgcg
    43441 cagaaacgaa aaatggaata gaggaaatta tgacaaaaca aaaagaaata acaactttta
    43501 acgttcaagt tgcggagttt attcgccatc acaaaaaaga aggaacagcg attgatgatg
    43561 acgtgaccga aaaacttgtc attccatttg ctttggatgc tgatcagatt gatgacttac
    43621 ttgagcggtt aacagatggt ggtatctcga ttacggataa agaaggtaac ccatcatcaa
    43681 aatacattgt tgaagaacca aaaccagaag aattaactga tgaagaatta attggtagta
    43741 attcagctaa agtaaacgac cctgtccgca tgtacctcaa agaaattggt gtggtaccgc
    43801 ttttaacaag tgaagaggaa aaagaattgg ctgttgcggt tgccaaggga gatttaatgg
    43861 ctaaacaacg tttagcggaa gcaaaccttc gtcttgttgt ctcaattgca aaacgttatg
    43921 ttggacgtgg aatgcaattt cttgatttaa ttcaagaagg taacatggga ctcatgaaag
    43981 ctgttgataa atttgattat tcaaaaggat tcaaattctc aacttatgca acatggtgga
    44041 ttcgtcaagc tataacacgc gcaattgcag atcaagcacg tacgattcgt atccctgttc
    44101 atatggttga aacgattaat aaattagtcc gtgaacaacg taaccttctt caagaacttg
    44161 gtcaagatcc aacgccagaa caaatcgcag aacgtatgga aatgactcca gacaaggttc
    44221 gtgaaattct aaaaattgct caagaacctg tttctttaga aacaccaatt ggggaagaag
    44281 atgatagtca cttaggtgat tttatcgaag atgaagttat tgaaaatcca gtagattata
    44341 cgacgcgtgt tgttcttcgt gagcaattgg atgaagtttt agatacgctt actgaccgtg
    44401 aagagaacgt tcttcgccta cgctttggcc ttgacgatgg taaaatgcgt acgttagagg
    44461 acgtaggtaa agtatttaat gttactcgtg agcgcattcg acagattgaa gctaaagccc
    44521 ttagaaaact tcgccatcct agtcgtagta aacaattaag agactttata gaggactaaa
    44581 atcgtccagt ggacgatttt aggtcgttcc tttgaaataa gaaaggagcg aaaatcccaa
    44641 gtggcactta tcagcggtac acctacaaat tagaaaacgg accgaatgtg gtgggtattt
    44701 ttaagggtag acttgatatc ttaaacaagc ccagagggca attcctctaa ataggcaaag
    44761 ctttagtggt ttttttactt atctacgaca tattcaaaaa atgaaaggaa agccatgtct
    44821 gatacaccaa aatatacaca agatcaggtg atagctatca agaatagaat tcttgaagct
    44881 ttagaaactg ttattgatcc cgagctaggt attgatgttg ttaatctagg tttgatttat
    44941 gaaattcggt tcaatgataa cggttataca gagattgata tgacactcac aacaatgggt
    45001 tgtcctttgg cagacttgtt gacagattac atccatgatg ccctgcaaga tgtgccagaa
    45061 gtcactaaga ctgaggtcaa attagtctgg taccctgctt ggacggttga taaaatgagc
    45121 cgctatgcta ggattgcgct gggtattcgc taatcattga tagtaaaggg atgaaatatt
    45181 cccttttttg atgtagaata aaaggaaata caggtgaaag cctttggtta atgttagaga
    45241 acactaagat actgagaaaa gtgttctacc tatggcaaaa aggagaactg atgattttaa
    45301 ttacaggaag caatggtcaa ttagggacag aacttcgata cttattagat gaacgaggtg
    45361 ttgattatgt agccgttgat gtcgcagaaa tggacatcac aaatgaagac aaagtcgaag
    45421 ctgtttttgc gcaggtcaag ccaacattgg tctatcattg tgctgcttat acggcagttg
    45481 atgcagcaga agacgaagga aaagccttga atgaggctat taatgtaaca ggctcagaaa
    45541 atattgccaa ggcttgtgga aaatatgggg ctacccttgt ttacatttca acagactacg
    45601 tatttgatgg caataaacca gtcggtcaag aatgggtaga aacagatcgt ccagacccta
    45661 agacagaata tggccgtaca aaacgtttag gagaactagc tgttgaacga tacgcagagc
    45721 atttttatat tatccgtact gcttgggtat ttggaaatta tggtaaaaac tttgtcttta
    45781 ccatggagca gttagcggaa aatcactccc gtttgactgt tgtcaatgac caacacggtc
    45841 ggccaacgtg gacaagaacc ttggcagaat tcatgtgtta tttgacagag aatcaaaaag
    45901 cctttggtta ctatcacttg tcaaatgatg ctaaggaaga caccacttgg tatgattttg
    45961 ccaaagaaat cttaaaagac aaggctgttg aagtggtgcc agttgattca tcagctttcc
    46021 cagcaaaagc caaacgtcct ttaaattcaa ccatgaatct tgataaggca aaagcaacag
    46081 ggtttgttat tccaacatgg caagaagcct tgaaggcatt ttaccaacaa ggactgaaaa
    46141 agtaagtatt ctaaaaagag ttggctttct aaggccaact ctttttcatg ggtttaaggt
    46201 cgcattagcc ttctaattgt ggtataatat cactgattat attttagaat ggggtagtat
    46261 gcaatgcagg atgtttttat cattggtagc agagggttac cagcgaaata cggtggcttt
    46321 gaaacctttg tcgaagagtt gattagtcat caatcatcta aaaacattcg ttatcatgtt
    46381 gcttgtttaa gcgatacgaa gcataaggtt cattttgatt ataagggggc agattgcttt
    46441 taccttaatc ccccaaaact tggtcctgct agagttattg cttatgatat gatggcaatt
    46501 acctatgccc tgtcttatag cgaccaacac cagattcaga accctatttt ttatgtgttg
    46561 ggcaatactg taggcgcttt tattgcgcca tttgtgaagc agattcacaa tcgaggtgga
    46621 cgctttttta tcaatccaga cgggttagag tggaaacggt ctaaatggtc aagaccagtg
    46681 caggcctacc tgaagttttc cgaaaagcaa atgactagac aggctgattt ggtcatttca
    46741 gataatattg gcattgaccg ctaccttaaa caagtttatc cttggtctaa aacatgtttt
    46801 attgcttatg gaacgcagac acaaccttca cgtttggcaa cagcagatag caaggtcaga
    46861 gcttattttc aaacctttga tattagagaa aaggattact atctcatttt aggacgcttt
    46921 gttcctgaaa ataattacga aaccgctatt aaagaattta tggcttcctc aactaagcgt
    46981 gatttagtga ttatttgtaa tcatgaaggc aatgcttact ttaagcaatt acttgctgag
    47041 acagagtgtg ataaagactc acgcattaaa tttgttggta ccctttatga caaagaacta
    47101 ttagcctaca ttcgagaaca ggcttatgcc tatatccatg gtcatgaggt aggagggact
    47161 aatccaggcc ttctagaagc actagcccat accaatctta atttggtttt aggagttgat
    47221 tttaaccagt cggtggctaa gtctgctgcg ctttattgga ccaagcaaaa agggcaatta
    47281 gcagagctga ttaaccaagt tgatgcaggt tttgatagtg atcgtctggg caaagaagcc
    47341 aaagctatta ttcaagaaca ttacacttgg gaaaaaattg taggggagta cgaggcttta
    47401 tttttaaatg aacattaata ttttactatc cacctacaat ggagaacgct tcttagcaga
    47461 acaaattcaa agtatccaaa ggcaaacagt taacgactgg accttattga ttagagatga
    47521 tggatcaact gatggcaccc aggatattat tcgcacattt gtcaaggaag acaaacgaat
    47581 tcagtggatc aatgaggggc agacagaaaa tctgggagtt attaagaatt tttacaccct
    47641 cttaaagcac caaaaagcag atgtctattt tttcagtgac caagatgata tatggttaga
    47701 caataaactg gaagtgacct tattggaggc tcaaaaacat gaaatgacag ctcctttatt
    47761 ggtttataca gacctcaaag tggtaaccca acatttagct atttgccatg acagtatgat
    47821 taagacccaa tctggtcatg caaacacaag cctacttcaa gaattaaccg aaaataccgt
    47881 aacaggcggc acaatgatga ttactcatgc tctggctgag gaatggacca cttgtgacgg
    47941 tttattgatg catgactggt atttagcttt actagcttct gctactggga aattagttta
    48001 ccttgatatt ccaacagaat tataccgtca gcacgatgct aacgtgttgg gagctagaac
    48061 ttggtctaaa cgcatgaaaa attggttaac cccccatcat ttagtcaaca aatattggtg
    48121 gttgattact tcaagccaaa aacaggctca attactatta gatttaccat taaaaccaaa
    48181 tgaccatgaa ttggtaacgg cctatgtttc tttattggat atgcctttta ccaaacgctt
    48241 agctaccttg aaaaggtacg gttttagaaa aaatcgcatc tttcacacct ttatttttcg
    48301 tagtttagtt gttaccttat ttggttacag gagaaagtaa gaatgaattt tttaacaaag
    48361 aaaaaccgta ttttactgag agaaatggta aaaacggatt ttaaattacg ctatcaaggg
    48421 agcgcaattg gctatctatg gtctatctta aaaccgctta tgatgtttac gattatgtac
    48481 ttggtattta ttcgttttct tcgcctgggt ggaaatgtac ctcattttcc agtagcgctt
    48541 ttattggcaa atgtcatctg gtcttttttt tcagaagcaa ctagcatggg aatggtatct
    48601 attgtatctc ggggagactt gttgcgaaaa ttgaactttt ctaagcacat cattgttttt
    48661 tcggcagtgt taggagcttt aattaatttt cttattaatt tggttgttgt tttaattttt
    48721 gcgttgataa atggtgtgac tatatcaggg tatgcttatc tctctctttt tctttttata
    48781 gaattagttg ttttagtgct tggaattgca ttgttattgt cgaatgtctt tgtttattat
    48841 cgtgacttag ctcaagtctg ggaagtacta ttacaagcag gtatgtatgc cactccaatc
    48901 atttatccga tcacttttgt tttagacagc caccctttgg cggcaaagtt gttgatgcta
    48961 aatccagtag cacaaatgat tcaagatttt cgttatttat tgattgacag ggccaacgta
    49021 acgatttggc agatgtcaac caattggttt tacattgtta ttccatattt agtaccattt
    49081 gttatattat ttattggcat ctttgtcttt aagaaaaatg ccgatagatt tgcggagatt
    49141 atttaatgat taatagagaa attgcagtaa aagtacagca tgttagtaaa acatttaaac
    49201 tgcctacaga agcaactaaa agttttcgca cgactctggt taatcgccta agagggatta
    49261 aaggatttac tgaacaacat gtgctaaaag atattaactt tgatgtttat aaaggcgatt
    49321 tttttggaat tgttgggcgt aacggctcgg gaaaatcaac gctccttaaa attatttccc
    49381 agatctatgt tccagaaaaa ggacaggtta cagtagatgg gaagatggtt tcttttatag
    49441 agcttggagt gggattcaat ccagaattaa caggacgaga aaacgtctat atgaacggcg
    49501 ccatgctggg atttaccaaa gacgaagttg atgatatgta caatgatatt gttgattttg
    49561 cagagttgca tcattttatg aatcaaaaat taaaaaatta ttcttctggc atgcaggtac
    49621 gtttagcatt ttcagtggct attaaagccc aaggtgacgt tcttatttta gatgaggtgc
    49681 ttgctgtagg agatgaagct tttcagcgaa aatgtaatga ttattttatg gaaagaaaag
    49741 acagtggtaa gacgactatt ttagtgacac atgatatggg agctgttaag aagtattgta
    49801 accgtgcagt tcttattgaa gatggtcttg ttaaagcata tggagaacca tttgatgttg
    49861 ctaatcagta tagtgtagat aatacagaga cagctgagga tgcaatgaat actgaaaaaa
    49921 tatctgtatc tgatattgcc aaagatttga aagtgtcatt aatctcaaat ccaagaataa
    49981 caccaaatga cacaatcaca tttgaagttt cttatgaagt tttaaaagat gattttacct
    50041 acattgcctt ttctttaacg gatattgata gaaacatttg ggtttacaac gacaattctt
    50101 tagattatcc aacacaaggt ataggtagaa aatgcatttc ctaccaatgt caactatctc
    50161 aacttaatga tataaaacta aaattagaag taactgtccg agataagaac ggtcagatgc
    50221 tactcttttc aacagcagaa caatcacccc agatagtgat tcaaagaaac gatattgatc
    50281 aagatgatct gtcagctcta gattcagcaa gtggcttgta tcaacgtaat gggaagtggg
    50341 tttttcatta atgagtaata gctagaaggg aatttatgta taaagtttca attatttgca
    50401 ccaattataa caaagctcct tggatatctg atgcacttga cagtttttta agccaagtga
    50461 cagattttga ggttgaaatt attgttattg atgatgcttc tacagatgac tcacgagaga
    50521 ttttaaagag ttatcaaaaa aagtcttcag gaaaaattaa attactcttt aacgaaacta
    50581 atattggaat aacaaagact tggataaaag catgccttta tgcaaaaggc aaatatattg
    50641 ctagatgtga tggtgatgat tactggacgg atagttttaa actccaaaaa caagttgatg
    50701 tcttagaagc ttccaaacgg tcacgatggt gtaatactga ttttgacttt gtaaatagtc
    50761 aaggcgactt attatatgct aatgcttttt catctggtca tacacctttg acagatactt
    50821 acgaaaaagt tttagcctta aaagggatga cgatggcatc gacatggtta gttgatgctg
    50881 atttaatgag acaagtaaac caaaaaatca atgtagatac accagacgat acttttgata
    50941 ttcaactaga gttatttcaa ctgactcaac tgacctatat taaagactca acgacgattt
    51001 atcgcatgac aaccgattct gattcaagac ctactgatac accaaaaatg attcatcgta
    51061 ttcaaaaact acttgatact cagttaaatt acttaaaaaa gtataatcag gtagatacaa
    51121 aagaagtgtc tgaactatta ttacaacaag atgctaagca agaaatacga attcatgagt
    51181 tgagttgctt tattcaagaa ttacaacaaa ctatcgtaga taaaacaaag cagcaagaaa
    51241 cacgtgaagt ggagttgcaa aatgtcatag aagaacaaaa aaatcaacta tctgaattaa
    51301 gacaacaata ccatgccatt attaattcac gtcaatggaa atacacgtct aagctcattg
    51361 cttttattag gagaaaaaaa tgaatcgtat tttattatat gttcacttca acaaatacaa
    51421 taaaataagt gcacatgttt actatcaatt ggaacaaatt agatcactgt tttctaagat
    51481 tgtttttatc tcaaatagta aagtgagtca tgaagattta aaacgtctca aaaaccactg
    51541 tcttattgat gagtttttgc aacgcaaaaa taaaggtttt gatttttctg catggcacga
    51601 tggcttgatt actatgggat ttgacaagtt ggaagagttt gactcattga cgattatgaa
    51661 cgatacttgt tttggtccta tttgggagat gggtccttat tttgaaaatt ttgaagaaaa
    51721 agaggcagtt gacttttggg gaattactaa taatagaggt acaaaagctt ttaaagaaca
    51781 tgtccaaagt tattttatga cgtttaaaaa tcaagtcatt caaaacaaag tttttcaaca
    51841 attttggcaa tcgataatag aatatgaaaa cgttcaagaa gtgattcagc attacgaaac
    51901 gcaattaaca tccattctct taaatgaagg ctttagttat cagacggtct ttgatactag
    51961 aaaaactgag tcgtcattca tgccacatcc ggatttttca tattataatc caacagcaat
    52021 tctaaaacac catgtgcctt ttataaaagt aaaagctatt gatgctaacc agcatatcgc
    52081 tccttactta ctgaatctga tacgagaaac aaccaattat cctatagatc ttattgtttc
    52141 acatatgtcg caaatctctt tgccagatgc taagtacctt ttatctcaaa aatacctaaa
    52201 ctgccaacgg ttagcaaaac aaacttgtca aaaggtagct gttcatttac atgtttttta
    52261 cgttgatttg ctagatgaat ttttaacagc tttcgaagac tggaacttcc attatgatct
    52321 ttttattaca acagatagtg atatcaaaag aaaagagatc aaagaaatac ttcaaagaaa
    52381 aggtaaaact gctgatatac gcgttacggg aaatagagga agagatattt atccaatgtt
    52441 attactaaaa gataaacttt ctcaatatga ttatattggt catttccata cgaaaaaatc
    52501 aaaagaagct gatttttggg caggagaatc ttggcgaaaa gaattgattg atatgctcgt
    52561 gaaaccagca gatagtattc ttagcgcttt tgagacagat gatattggta ttataatcgc
    52621 agatattcca agttttttta gatttaataa gattgtcaat gcttggaatg agcatttaat
    52681 cgctcaagaa atgatgtctt tgtggagaaa aatggatgtt aaaaaacaaa ttgattttca
    52741 agctatggat acatttgtta tgagttatgg aacatttgta tggtttaaat acgatgctct
    52801 aaaatcactt tttgatttag aattaactca aaatgatatt ccaagtgaac ctttaccaca
    52861 aaactctata ttacatgcga ttgagcggtt acttgtctat atagcgtggg ggaattctta
    52921 tgattttagg attgttaaaa atccctatga gttaacacct tttattgaca ataaactgtt
    52981 aaatttacgt gaagatgaag gagctcatac ctacgttaac tttaatcaaa tgggcggtat
    53041 caaaggagca ttaaaatata ttatcgttgg tcccgctaaa gcaatgaagt atatattctt
    53101 gcgtttaatg gagaaactta aatgattaaa gacacatttt taaaaaccaa ttggttaaat
    53161 atcagtcacc atattatcct tcttgttttc ggtttttatt tcagttttta cagtttggcg
    53221 aaagaactag taagctccac gacacaaccg gtaaactatt atactcattt actaaatgtt
    53281 tcttttgtgg gatatattat atcactgatt ggattatctt attatttgag tcgccaagtt
    53341 agtcgacagt tgtttttgaa aactagtttt attgtgatat cttatctaat tgtcagctat
    53401 tgggtacaaa taacacagca cctgaatgat aaacggtttg atatctggtc attaactaaa
    53461 aatcaatttt atcaatttca agctctacct tctttactca ttattttagt gatggccact
    53521 ttaataaaaa tattggtagc atattttgca atagaaaaag atagatttgg gctattaggc
    53581 tatcaaggta atactttttc tgtagctctg attttagcag ttgtgccaat taatgacata
    53641 catctgttaa aactaataag ttctcgattt tctgaattag taacagcagg taatagccaa
    53701 attgcactgt taaaaataag tggactgttg atagttttac ttgtcatatt tgcaacaatc
    53761 atatacgtgg ttttaaatgc tctaaaacac cttaagtcaa ataaaccttc attttcagta
    53821 gcagctacta ctagtttgtt tttagcatta gtttttaact atacgttcca gtatggagta
    53881 aaaggtgatg aagcattgct aggatattat gttttccctg gagctactct ttttcagata
    53941 gtagctatta cactagttgc tcttttagca tacgtgataa cgaatagata ttggccaact
    54001 accttctttt tgcttattct gggaacaatt atttctgttg ttaatgattt aaaagaatca
    54061 atgagaagcg agccattatt agtaactgat tttgtttggt tacaagaatt aggtttagtg
    54121 acaagctttg ttaaaaaatc ggtgattgta gaaatggttg taggacttgc tatttgtatt
    54181 gtggtggctt ggtatctaca tggccgagtt ttagcaggga aattatttat gagccctgtc
    54241 aaacgggcaa gtgctgtatt aggtttattt attgtatctt gtagtatgtt aataccattt
    54301 tcttatgaaa aagaaggtaa aatattatct ggtcttccga ttatttcggc tttaaataat
    54361 gataatgaca taaactggtt aggtttttca acaaatgcta ggtacaaatc tttagcatat
    54421 gtttggacaa gacaggtgac caagaaaata atggaaaaac cgacaaatta tagccaagac
    54481 acaatagcga gtatcgctca gaagtaccaa aaattagcag aagatattaa taaagacaga
    54541 aaaaataata ttgctgacca aacggttatt tatcttttaa gtgaaagctt gtcagatcct
    54601 gatagagtat caaatgttac tgttagccac gatgttttac ctaatatcaa ggcaatcaaa
    54661 aatagcacaa ctgcgggact catgcagtca gactcctacg ggggtggaac tgctaacatg
    54721 gagtttcaaa cgttaacaag cttacctttt tataattttt cttcttcagt atctgttctt
    54781 tattcagaag tctttcctaa aatggccaaa cctcatacga ttagtgagtt ttaccaagga
    54841 aaaaatcgta ttgcgatgca tcctgctagt gctaacaatt ttaatagaaa aacagtttat
    54901 agtaatttag gtttttccaa attcttagct ctatcgggtt ctaaggataa gtttaagaac
    54961 attgaaaatg tcggtttatt gactagcg
//
LOCUS       DAUGSW010000009        53641 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUGSW010000009 DAUGSW010000000
VERSION     DAUGSW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53641
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.009"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(238..870)
                     /locus_tag="VIB18_000620"
     CDS             complement(238..870)
                     /locus_tag="VIB18_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEQ8765649.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     LSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTVFHKVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            complement(870..1634)
                     /locus_tag="VIB18_000621"
     CDS             complement(870..1634)
                     /locus_tag="VIB18_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEQ8765650.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            complement(1634..2386)
                     /locus_tag="VIB18_000622"
     CDS             complement(1634..2386)
                     /locus_tag="VIB18_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEQ8765651.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQIISDGQLNAQAMIEWRAIKPIESETD"
     gene            complement(2396..3526)
                     /locus_tag="VIB18_000623"
     CDS             complement(2396..3526)
                     /locus_tag="VIB18_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEQ8765652.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKAAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            complement(3589..4230)
                     /locus_tag="VIB18_000624"
     CDS             complement(3589..4230)
                     /locus_tag="VIB18_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765653.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDT
                     QNRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLHAKGCKPGNENDSDVCQLVKYFSKP"
     gene            complement(4354..5709)
                     /locus_tag="VIB18_000625"
     CDS             complement(4354..5709)
                     /locus_tag="VIB18_000625"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEQ8765654.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDVEVDYYVDTIADVVRTEIGCD
                     N"
     gene            complement(5763..6719)
                     /locus_tag="VIB18_000626"
     CDS             complement(5763..6719)
                     /locus_tag="VIB18_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEQ8765655.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            complement(6716..7567)
                     /locus_tag="VIB18_000627"
     CDS             complement(6716..7567)
                     /locus_tag="VIB18_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEQ8765656.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            7674..9017
                     /locus_tag="VIB18_000628"
     CDS             7674..9017
                     /locus_tag="VIB18_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEQ8765657.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     ERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFVCLNCQFQRPTLDYQLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI"
     gene            9017..9808
                     /locus_tag="VIB18_000629"
     CDS             9017..9808
                     /locus_tag="VIB18_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEQ8765658.1"
                     /translation="MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(9917..10906)
                     /locus_tag="VIB18_000630"
     CDS             complement(9917..10906)
                     /locus_tag="VIB18_000630"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8765659.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILAKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            11139..13556
                     /gene="hylA"
                     /locus_tag="VIB18_000631"
     CDS             11139..13556
                     /gene="hylA"
                     /locus_tag="VIB18_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEQ8765660.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTCLWEHAKDYSASTNITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKSYHDIKLMKELL
                     SDTFVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQEGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATTFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            complement(14231..15994)
                     /gene="lpdA"
                     /locus_tag="VIB18_000632"
     CDS             complement(14231..15994)
                     /gene="lpdA"
                     /locus_tag="VIB18_000632"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEQ8765661.1"
                     /translation="MAVEIIMPKLGVDMAEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAM
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(16321..17730)
                     /locus_tag="VIB18_000633"
     CDS             complement(16321..17730)
                     /locus_tag="VIB18_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEQ8765662.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGNTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPAVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPTASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINNANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(17915..18913)
                     /locus_tag="VIB18_000634"
     CDS             complement(17915..18913)
                     /locus_tag="VIB18_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEQ8765663.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIIDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(18972..19940)
                     /locus_tag="VIB18_000635"
     CDS             complement(18972..19940)
                     /locus_tag="VIB18_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEQ8765664.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(20225..22132)
                     /locus_tag="VIB18_000636"
     CDS             complement(20225..22132)
                     /locus_tag="VIB18_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8765665.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTPSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQEALME
                     EWETIAEQIES"
     gene            complement(22178..22504)
                     /locus_tag="VIB18_000637"
     CDS             complement(22178..22504)
                     /locus_tag="VIB18_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765666.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKMRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(22534..23319)
                     /locus_tag="VIB18_000638"
     CDS             complement(22534..23319)
                     /locus_tag="VIB18_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEQ8765667.1"
                     /translation="MANIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIDDF
                     QAQGLDIDYHKSHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(23452..25113)
                     /locus_tag="VIB18_000639"
     CDS             complement(23452..25113)
                     /locus_tag="VIB18_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8765668.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYFKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            complement(25317..26075)
                     /locus_tag="VIB18_000640"
     CDS             complement(25317..26075)
                     /locus_tag="VIB18_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765669.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSHSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(26072..26941)
                     /locus_tag="VIB18_000641"
     CDS             complement(26072..26941)
                     /locus_tag="VIB18_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765670.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERFFKGVRLTR"
     gene            complement(27117..27335)
                     /locus_tag="VIB18_000642"
     CDS             complement(27117..27335)
                     /locus_tag="VIB18_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765671.1"
                     /translation="MLLTGKIFLQLLLLRINTKTCDIKGQEKIIKNTLTEMNLDAKSD
                     NRLEDVTVIFIIFSFKMLYFRHVKNLAF"
     gene            complement(27286..28284)
                     /locus_tag="VIB18_000643"
     CDS             complement(27286..28284)
                     /locus_tag="VIB18_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8765672.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQPNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            28638..30290
                     /gene="fbp54"
                     /locus_tag="VIB18_000644"
     CDS             28638..30290
                     /gene="fbp54"
                     /locus_tag="VIB18_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEQ8765673.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPIFGRLQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSMVPNNQDSVVLDN
                     YYTGEKLEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(30349..31596)
                     /locus_tag="VIB18_000645"
     CDS             complement(30349..31596)
                     /locus_tag="VIB18_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEQ8765674.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSLNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVGISPEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLMYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEIFMRLATLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(31586..32767)
                     /locus_tag="VIB18_000646"
     CDS             complement(31586..32767)
                     /locus_tag="VIB18_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8765675.1"
                     /translation="MPLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(32825..33301)
                     /locus_tag="VIB18_000647"
     CDS             complement(32825..33301)
                     /locus_tag="VIB18_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEQ8765676.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(33522..34562)
                     /gene="rfbB"
                     /locus_tag="VIB18_000648"
     CDS             complement(33522..34562)
                     /gene="rfbB"
                     /locus_tag="VIB18_000648"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEQ8765677.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(34807..35400)
                     /locus_tag="VIB18_000649"
     CDS             complement(34807..35400)
                     /locus_tag="VIB18_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEQ8765678.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(35400..36269)
                     /gene="rfbA"
                     /locus_tag="VIB18_000650"
     CDS             complement(35400..36269)
                     /gene="rfbA"
                     /locus_tag="VIB18_000650"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEQ8765679.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(36327..37436)
                     /locus_tag="VIB18_000651"
     CDS             complement(36327..37436)
                     /locus_tag="VIB18_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEQ8765680.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQELVSDLQTEGFATDFYQQNGIYLLKKQEEKLKD
                     LYQLALSRQEESTLIGHLEVKKREEIQEEAFPGLVGFDNCLYASGAARVEGAALCETL
                     LKASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKG
                     QLLDYDIHHIISDNYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQILEKL
                     EMQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGP
                     LIGYELAQLLLGHEGLLTPSDYSPEPYLLRSAGKA"
     gene            complement(37476..38264)
                     /locus_tag="VIB18_000652"
     CDS             complement(37476..38264)
                     /locus_tag="VIB18_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEQ8765681.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(38254..38940)
                     /locus_tag="VIB18_000653"
     CDS             complement(38254..38940)
                     /locus_tag="VIB18_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEQ8765682.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKVLSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(39012..39668)
                     /gene="nth"
                     /locus_tag="VIB18_000654"
     CDS             complement(39012..39668)
                     /gene="nth"
                     /locus_tag="VIB18_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEQ8765683.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSSDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(39665..40348)
                     /locus_tag="VIB18_000655"
     CDS             complement(39665..40348)
                     /locus_tag="VIB18_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ8765684.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVMISEDFL
                     SAMNLWSDS"
     gene            complement(40429..40947)
                     /locus_tag="VIB18_000656"
     CDS             complement(40429..40947)
                     /locus_tag="VIB18_000656"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEQ8765685.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(41097..43307)
                     /gene="recJ"
                     /locus_tag="VIB18_000657"
     CDS             complement(41097..43307)
                     /gene="recJ"
                     /locus_tag="VIB18_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEQ8765686.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLIADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(43304..44068)
                     /locus_tag="VIB18_000658"
     CDS             complement(43304..44068)
                     /locus_tag="VIB18_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ8765687.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIAGM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(44068..44997)
                     /locus_tag="VIB18_000659"
     CDS             complement(44068..44997)
                     /locus_tag="VIB18_000659"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEQ8765688.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(45012..45647)
                     /locus_tag="VIB18_000660"
     CDS             complement(45012..45647)
                     /locus_tag="VIB18_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEQ8765689.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFDQGQSEDITPD
                     DALLTKIYRLKNDVVLLKGFNVDELCTLSQAFTGQRYYDFAQREFMIYITQ"
     gene            complement(45640..46878)
                     /gene="hflX"
                     /locus_tag="VIB18_000661"
     CDS             complement(45640..46878)
                     /gene="hflX"
                     /locus_tag="VIB18_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEQ8765690.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(46951..47850)
                     /gene="miaA"
                     /locus_tag="VIB18_000662"
     CDS             complement(46951..47850)
                     /gene="miaA"
                     /locus_tag="VIB18_000662"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEQ8765691.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPYYPQVVHDRVRDFLGQKEKS"
     gene            47984..48160
                     /locus_tag="VIB18_000663"
     CDS             47984..48160
                     /locus_tag="VIB18_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEQ8765692.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(48278..49186)
                     /locus_tag="VIB18_000664"
     CDS             complement(48278..49186)
                     /locus_tag="VIB18_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEQ8765693.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFNYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(49423..49842)
                     /locus_tag="VIB18_000665"
     CDS             complement(49423..49842)
                     /locus_tag="VIB18_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEQ8765694.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMI
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDGLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMVEDSAVQQVLNAAH"
     gene            complement(50153..51139)
                     /locus_tag="VIB18_000666"
     CDS             complement(50153..51139)
                     /locus_tag="VIB18_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEQ8765695.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            51340..51642
                     /locus_tag="VIB18_000667"
     CDS             51340..51642
                     /locus_tag="VIB18_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765696.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(52005..52076)
                     /locus_tag="VIB18_000668"
     tRNA            complement(52005..52076)
                     /locus_tag="VIB18_000668"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52041..52043),aa:Arg,seq:ccg)
     gene            complement(52189..53394)
                     /gene="rpsA"
                     /locus_tag="VIB18_000669"
     CDS             complement(52189..53394)
                     /gene="rpsA"
                     /locus_tag="VIB18_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEQ8765697.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            complement(53521..53592)
                     /locus_tag="VIB18_000670"
     tRNA            complement(53521..53592)
                     /locus_tag="VIB18_000670"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53558..53560),aa:Gln,seq:ttg)
BASE COUNT        16313 a        11426 c         9411 g        16491 t
ORIGIN      
        1 tctttgaatt tctccttgat tatttgttat aaaagttata aaataatctt gttggaacca
       61 ttcaaaacag catagcaagt taaaataagg ctagtccgtt atcaacttga aaaagtggca
      121 ccgagtcggt gctttttttg atacttctat tctactctga ctgcaaacca aaaaaacaag
      181 cgctttcaaa acgcttgttt tatcattttt agggaaatta atctcttaat ccttttatca
      241 ttctacattt aggcgctgcc atcttgctaa acctactaag ctccacagga tgatttcgta
      301 aactatcata aagaaaagga aacagtgcaa gaaaaagact tctggaagga tccaaatcac
      361 aggatctttc aagggatcaa agagccagct gctatctcct acaaaaagca ccttatgaaa
      421 aacagtaaaa aaatgttcaa acccaatgaa actagccatt agaccaatca taagaggaaa
      481 caaagctgct agtattaaag gtttttgaag gagccagaaa cgtttggttt ttaacctttg
      541 tgtgaaagtc ttaagggttg ggtaaaggag gccaagaaaa acgacttgag ttaggtgaaa
      601 aagccacttc acatctgcaa aatgcttgag tccgtctgct gacgagtgaa aattagcaaa
      661 ttccaacctt gttacaaaag gattggtaag gtaatttagt agtccgttat agttatgcaa
      721 gatagcatcc ttgctcaaaa aaacaacttg ttctaacttt agatggtcca cctcaagagg
      781 ataccacagc cacgttgaat agatcgttat gagaatagct aacgctaata accataccca
      841 gctacatagt aatttagtgt tttcgaccat cacaacctcc actcatcaag gctagatagg
      901 acatgatctg gctgaattgg taaggttggt acctcttcag gtctggtaaa gcctgttgtc
      961 acgaggatcg ttgcaatatc attttgaata cctgccatga tatcagtcaa gtaattatcg
     1021 ccaaccatga cagcctcaga gcgctgaatg cccaatacct ctagtgattt attcataatg
     1081 atagcgttgg gcttgccaat aaaaacaggt tttacacgtg tggcagcttc tagtaaggca
     1141 ttcaatgcac ctgctcctgg catcaaacca cgttcggttg gaatgtttaa atcaggattt
     1201 gtcccaataa agagggcacc tttttgaata gccaaggtgg ctatagccaa catctcatag
     1261 gtcacctgac tgtctaaacc aaccaccacg taagcgggat tctcaagttc ttctacgtaa
     1321 cctgctgctg caatcgctga tttgagccct gtttctccaa taacgtaagc tgtcttgcca
     1381 cggttcatgt cattcatgta atcgacggtt gccatggtag ccgtataaat ggtctcaatg
     1441 cctgtctcaa cattaaactg attagccagc atgctttgca ccatttcggg tgttcttgtg
     1501 gtattattag tcactaataa atagggaatg cctctttctt gtaggcgttt gataaaccgc
     1561 tcccctgctg gaatacggtt tttcccttgg taaatcgttc cgtctaaatc aattaaataa
     1621 cccttataag gcactagtct gtctcacttt ctattggttt aatcgctcgc cattcaatca
     1681 tggcttgggc attcagctgc ccatctgaga tgatttgatg gtaagaagtt aattggtcca
     1741 aatggtaact ggaagtaatt tgaccgcctg gtgagacttc tttaacatat ttcaaagtca
     1801 tcttaagagg ctgatgcgtt tttaaaaact cacaccccaa cacatcatac atccaatcta
     1861 aatatttact gttgttaacg tgaccattca tatcaatatc aaaataacgc acataataat
     1921 cacgatcaat tgattgttct aaaagaggca ttttaggaac acggtgtagc tttttaacaa
     1981 aatcagtctt aaaaggtgct actaaatctt ctggaatagt tgccactttt cgcgtatctg
     2041 ggtttaacaa agcaaaatag gctaagatat ccactaaaag acccccctct tgatcataaa
     2101 tataaaattg gcgataacaa aaaaatttat tgtaggagag ggcttttgtt tcaatggtga
     2161 tggtttcttg aaaatgtggc aagcgatgaa tagtgatctc ataatccgtt acaatccaaa
     2221 caagcttgta atcaactaaa agattgttgt tacttcgtcc taattgcgca gactgtctac
     2281 cagaaaccat caaacaatag tctaataaaa ggggcaattt tatatctgat ttgacatcac
     2341 ataattcaaa aggaagtgtc aactcctcct gataacttaa tcccataata ctctcctaat
     2401 ctaatataaa ccgctcagca acagaatcac ctaagaaaag acccttttta gtcattctga
     2461 caaaggcgtc atctttgaca agcagtcctt ggttttgaag ctccctaaca atatttccat
     2521 aacgctcctc aaaagacata ccaaattttt cttggaaccg ctggatggag actcctgtct
     2581 ttttacgtaa gcccaaaaag agttcctctt ccatcatttc ctctttgcgc agcacttctt
     2641 catttagtct agcgtttcct gcttcaaccg ctttaagata atgctggatg ggcacccgat
     2701 tttgataacg aatgccatta aggtaacctg aagcccctgc accacatcca aaatactcca
     2761 cattatccca atacatcaag ttatggcgac tttcaaaacc tggtttggta aaattagaga
     2821 tttcataatg ttcaaagcca ttagcttcca tttctgaaat aatatactca aacatttctg
     2881 cttccaagtc ttccgttggt aagttaagtt taccacgccg cattttgttc ataaaaacag
     2941 tgtgatgttc caaaataagg ctataaagac taaggtgggg aatatcaagt gccaaagctt
     3001 tagcaacatt ttccttgact tgatctaagg tttgacctgg caaggcataa attaaatcaa
     3061 tggaaatatt gtgaaagcct gcagctttta aattagcgat ggtgctataa atttgttctt
     3121 cattatggct acggccaatc tgctttaatt gcttgttatt aaaagtctgc acccccaagg
     3181 aaatccgatt gacagctgac ctctgaagca ccgcaatttt ttctggcgtc aaatcaccag
     3241 gatttgcctc aattgtgaat tcttcaagat catctaaatt gaggtttcgt tcaaggtgat
     3301 ttaggagata ctccaactgt ttagctgtga tagctgtagg cgtacctcct ccaatataaa
     3361 gggtttttag gtctcgaatg ccataagagt caaattcttg aatcaaggct ttcaaataag
     3421 catcaacagg ttgattttgg ataaagactt ttgaaaaatc gcaataataa caaatttgtg
     3481 tgcaaaaagg aatgtgcaca taggctgaag taggtttttt tgacatggtc ttattatacc
     3541 actttgatga taaaatgttt ctatgaataa accatttccc ttgattcttc atggcttgga
     3601 aaaatatttt acgagctgac aaacgtcaga atcattttcg tttcctggct tgcaaccctt
     3661 agcgtgcaaa acaaatcctt gttcttggta aaaaagcttg cttgattctt gactgaccat
     3721 aatgcttaaa gaagggagtt tctcttgcat atctgccaga agatatgtct ggacagcctc
     3781 cacaatagct gctggaacct cgttttctgt cactgtttca agaatcccta aagtcatttc
     3841 tagaaattcc cccttttctt gaagaatcac aaaggctact cttgctccat ttcgaagcac
     3901 ttgaaaaagc gtctgatcct cgttaacagc agccgcaaac acttgattag ctgcaactgt
     3961 cgataacaaa tgataagcta ggcctttatc tgctagcaat tgctctgctg tttttcttgt
     4021 cacaggcatc acataaaaag atggggtatc tagtaatcgt tcaaaatttt tagttaactg
     4081 cttgatgcga cggttttgag tatcttcttt ttgggtttga taaacatatg aagcataacc
     4141 ttcctgaaat tcaggaatca tatctaagta aagtgtggct gcaaaaggag gcagtaagtc
     4201 cgctagtttt tcgatttgct gttttgtcat ccgatatcct ttctcttcta ctttagcaat
     4261 ttataaaaag agacttgggc taaacgcccc aagcctcttt ccaattgttg acagaagcct
     4321 tagaaataag gtttcttgtt tgtactcaac tcgttagtta tcgcatccga tttctgtacg
     4381 gacgacatca gcaatagtat cgacataata atcaacttcg acatctgttg gcgcctctgc
     4441 catgacacga agaagaggtt ctgtaccact tggtctcacg agaatacgac cattaccagc
     4501 catttcatcc tccatttttg caatgatgtt cgcaatagct ggaacttcca tagcacggtc
     4561 tttcatgctg ttttccacac gaatattcac cagtttttga gggtaaatgg ttacttcagc
     4621 agctaattcc gaaagtgatt tcccagtttc cttcatcacc ttggctaatt ggatagctgt
     4681 caactgacca tctccagtgg tattgtagtc catgataatg acatggcctg attgttcacc
     4741 accgagattg tatcctgagc tacgcatttc ttcaaccaca tagcggtctc caactgctgt
     4801 aattgcttta ttaatacctt gtttatctaa agctttatga aaaccgaggt tagacatcac
     4861 cgttgtgaca atggtattgt gagcaagaag ccctttttct gacaagtatt taccaatgat
     4921 aaacataata cgatcaccgt caacaatctc accagtttcg tccacggcaa tcagacggtc
     4981 gctatcgcca tcaaaggcta aaccaagatc tgctcctgtt tccttaacta actcttgaag
     5041 ttgttctgga tgcgttgaac caacaccgtc attaatatta agaccatttg gtttttcgcc
     5101 aatgacagca atttctgcat ttaaatctaa aaagacatca cgtgctgaca ctgaagcagc
     5161 tccattagca gtgtctaaag caactgtcat accgcttaag tcagtacctg ttgttaccaa
     5221 gaacttttca tatttacgaa gtccttctgg ataatctacc aaggttccaa gtccttctgc
     5281 actcgggcga ggaagcgtgt cctccggagc atctaagaga gcttcaattt ccaattcttg
     5341 gtcatcagct aacttaaacc catcattccc aaagaatttg atgccattgt caagcgcagg
     5401 gttatgactt gcagaaatca tcacacctgc acttgctttt tctgttctaa ctaaataaga
     5461 gacaccaggt gtcgctaaaa cgccaagttt ataaacttca ataccaacag atagtagacc
     5521 agcaatcaag gctgactcca acatttctcc tgaaatacgg gtgtcacgcg ccacaaaaac
     5581 tttaggtctt tcggtctcat gttgacttaa aacataacca ccgaatcggc ccagtttaaa
     5641 agctaactca ggtgtcagct caacatttgc ttcgccacga acaccatctg ttccaaaata
     5701 ttttcccata atttatataa gcctaatggc ttcctccatt caattttcct agttattatc
     5761 cattattttt tggtggttgt caactgaacg gtcactactg acggctcaat tgacacctga
     5821 ctagaagaca aactcacggt cttactagta tttttagtga catcagaaat gttaacttct
     5881 gcaataattt catcaatatc ttctaagacc tctcgactac ctgagataac agctgtttgt
     5941 tttgacaatt tgtattgaat atctgataag ctatcatcca tcatccccac tgcctcaact
     6001 ctaatcggga ctgatttcgt tatttttttt acagcaactg ataaatttgt ttttgcagga
     6061 tcaattgcac ttgctaaaat agttccatca gctgagacag cttgtaaggt cactcgacta
     6121 ctataattcc tatctaacac ttgatcatca ggtaactttg ccacaacgtg atcaattaaa
     6181 gcaatggtag attcatcact ggtcacttca accttattaa cccccgtttc aattttgcta
     6241 atttcataac catttgcaat ttgtttagca tcaacgcttc ctctaacagg aaatacctta
     6301 gattcttttt tgccaattgt gactgatatt ttatctggag atacggtagc tgtcacccca
     6361 gaagggaggt tttctactct taggttgaca tttactgtac ctggatgact atgtgttaga
     6421 tccgccacaa tcttaaaatt acgtgtatca ttgttcactt cagaatctaa tttgatacga
     6481 ttagtggagg ttagataaac ttccgcacca taagaatacc cactgataaa atatttgtca
     6541 ctatcatact tcatatcaat tggtacatct ttaaggctat gcgtataggt ttcaatcggg
     6601 ctataaattt gcgagctaga gttattatga ttgctcgatg ctgcagttaa aaaaaggaga
     6661 atcgcaaaaa agactgatac cattcctaac caaggacgac tatttaaaaa tcgtttcatt
     6721 tagatttccc tcctagaatt ttcttatacc atggtaaact aacatttgaa tcactcatca
     6781 ggtaggtcct aagtaccgtt tcaaattcat ctgtgcttaa atcgtgtaaa aattggcctt
     6841 tgcgagttac tgaaatagct cctgtttctt ctgaaacaat gatagttagt gcatcagagt
     6901 tttcagataa tccaatagcc gctctatgac gggtcccaaa ttctttggaa attgcctttg
     6961 attctgacaa aggcaagtaa gcacaggctg ccacaatctt attctgacca acgataacag
     7021 ctccatcatg aagcggcgta ttcggaataa aaatattgat gagtagttga cttgaaatat
     7081 cggcattcag cggaattcct gtcgcaatat attcttgtaa ggtttgagtc tgttcaatag
     7141 caatcagtgc acctatcttg cgtggaccca tataggccac agatttaatc aaagcatcga
     7201 ccaaagcaga ttcactgctg acgtactgtt tttgtaaaaa aacttgcgta gaacgaccaa
     7261 atttctccag tcctgcccga atttcagggg taaaaatgac tactcctgca attacaccat
     7321 aagtaatgac ttggttcatt aagtatgtga ttgtcgtaaa gccaatccac tctgcaataa
     7381 aacgaagaac caaaaagaaa atgacccctt gaactaaaga catgatttta gttccagtca
     7441 atgctttaat aaaacgataa atcaaatagg caacaattag aatatctaaa agatgcactg
     7501 ccagcagcca aggatccgca aataagctta ataaaaattt aatatcgata ctagataaat
     7561 tattcataca actctcattt ctatatcaaa aaagttatta gctatattat atcatatcat
     7621 gatcaaagat ttttccctat ctaaaatcaa taaacttatg ataaaatata agcatgaaaa
     7681 tgaagacatt actcggcatt attgctggca aagctgctca atccatttta acaaaactag
     7741 ggcgaggatc tacttatcct ggtcgattgg ctctagcttg tgataaagat attttaaagg
     7801 atttgtctaa agactatgat attgtggtcg tcactggtac taatggtaaa acgttaacaa
     7861 ctgctcttac tgtcggtatt ttgaaagagg catttggcga gataatcaca aatccaagtg
     7921 gtgccaatat gattactgga attacttcta cttttttagc tgctaaaaaa gggaaatctg
     7981 aaaggcaaat tgctgtttta gaaattgacg aggctagtct tcctagaatt accacttact
     8041 taaaacctag tctttttgtt tatactaata tttttaggga tcagatggac cgctacggag
     8101 agatttacac tacttatcag atgattgtag atggtgctcg aaatgctcca aaagcaacta
     8161 ttctagccaa tggagatagt cctattttct cttctaagga catagttaat ccagttcagt
     8221 attatggttt tgatactgct aagcatgctc cgcagctagc tcattacaac acagaaggga
     8281 ttttatgtcc aaaatgcgaa catattcttc agtatcgtct caatacttat gcgaatctag
     8341 gagactttgt ttgcttaaac tgtcagttcc aaagaccaac gttagattat caattaactg
     8401 agctcaccgc tattactcac caaagttctg aatttgttat tgatggacaa aactacaaga
     8461 taaatgttgg tggtctttat aatatttaca atgcgcttgc tgccgtctct gttgctgaat
     8521 ttttcggtgt ttctcccgag aaaatcaagg cgggctttaa caaaagtaag gcggtttttg
     8581 gaagacaaga aacttttact attggtgata aatcatgcac ccttatcctt atcaagaatc
     8641 ctgttggagc cagtcaagcg cttgaaatga ttcagctagc tgattaccca tttagcttat
     8701 ctgtgctttt aaatgctaat tatgctgacg gcattgatac cagctggatt tgggatgcta
     8761 attttgaact cattacccaa atgcccatta cagaaattaa tgctggcggc gttcgtcact
     8821 ctgaaattgc tagaagactt agagtcacag gatttgacga tactaaaata aagcaagctg
     8881 aaaagctcga gcaaatcata gaaactattg aaaaacaaga agctaagcat gcctatattt
     8941 tagcaaccta tacagcaatg ttagaattcc gtagcttact tgctgaccgc catgtcgttg
     9001 aaaaggagat gatctaatga catacacttc actaaaatct cccgaaaatc aagactacat
     9061 ctacgacctc aatatcgccc atctctatgg taatcttatg aatacttatg gtgataacgg
     9121 caatatttta atgctcaagt atgtcgctga aaaacttgga gctagggtta ctgttgatat
     9181 tgtatctatc aatgatacct ttgaacaaga cgattacgat attgttttct ttggtggtgg
     9241 tcaagattat gaacaaagca ttgttgccaa ggatttgcct agcaaaaaag ctgccttagc
     9301 agattacatt gctaataata aagtggtgct tgccatctgt ggtggcttcc aattactagg
     9361 gcaatactat gtccaagcta atggggttaa aattgatgga cttggaatta tgggacacta
     9421 cacccttaat cagcaccaaa atcgctttat tggagatatt aaaattcata atgacgaatt
     9481 taacgaaacc tattatggct ttgaaaatca tcaaggacgt accttcttat ctggtgacga
     9541 aaagccactt ggacgagtgg tttatggcaa cggtaataat aaagaagacc aaactgaagg
     9601 tgttcactat aaaaacgtct atggtagtta tttccacggt cctatcttat cacgcaatgt
     9661 taatcttgct taccgcttag taacaacagc tcttaaaaaa aagtatggat cagctatttc
     9721 actacctagc tatgatgata tactgaaaca agaaatcact gaagaatatg ccgaccttaa
     9781 aagcaaagct tcctttaata aagtttaagt tcttctttca tgtcatcaaa caaaaactcc
     9841 taagcaggac acgatagttc gcttaggagt tttatagttt tttcttctga cagagcttct
     9901 taagtgatta aaaccactaa gaaacaatag ctttagcaac ttcttcaacg gtcatgcgtg
     9961 agaagtactg ggtcgtatca atcgttttta aacgttcaaa aacatcacgg tactcatatt
    10021 tacaaccaat taataagttc tcaatgtctt gcacatcttt gattccaaag aaatcaccat
    10081 agattttaag gtttttaatg atagaatttt caacatttgc aaaggttgaa attttacctg
    10141 cagggtaacg aacattgcgt tcaatcgtat attctggcgc tttgccgtag gtccaatccc
    10201 agctaccaaa ttgctctttg gcagattgtt caatcttagc caactcatcc tctgacaaga
    10261 catattctgt catgtctggg tacgtttctt tcatcttggc caagatttta tctgaaaatt
    10321 cctcaacggt aattttttct ggtaattcat ttaaaatatt ggtcacgcga gcacgaacag
    10381 acttcactcc tttagactca atcttatcct tacttacctt aagagcatcg ccaagaacgg
    10441 tcatatccac atcaaacaaa aggcaaccat ggtgcatcat gcgacccttg taataggctt
    10501 gagcattacc acagattttt ttgccatcaa tctcaatatc attacgacct gtaaaattag
    10561 ctgtcacacc taaatcagct aaagtcgcaa tcacaggttg tgagaaagtt ttgaaatcaa
    10621 aagccccttc agctgttttg ttagaaataa tagtgtagtt caagttattc aaatcatgat
    10681 aaaccgcacc accaccagat aaacgtcgca caacatgaat accatgttca tcaatgtatt
    10741 ctttattgat ttcttgaatt gtattttgat gtttgccaat aataatagct ggctcattga
    10801 tccaaaggat aaacaattca tcttcttcca ctagttctct aaaagcataa gcttccagag
    10861 caatgttaaa ggcaggattg tgacttttgt taacgatgta tttcatagga gaaaaaatcc
    10921 tttcaaaaat gtaatctacc tctctagtat aatgaaaaca aatataaaag acaagtgtcc
    10981 tattctgtat gacatcttca gtacctacac ttattagtgc acaaaaactc agccattatt
    11041 tatgtaaggg tttataaaaa tactttaacg tggtatattt ttacttagta aaccaatcta
    11101 cttttattat ctcattttta tattggagga atttatcagt gaatacttat ttttgcacac
    11161 accataaaca attactactt tattcaaacc tattccttag ctttgctatg atgggccaag
    11221 gaactgccat ttatgccgat acactgactt caaattcaga acctaataat acttactttc
    11281 aaacgcaaac gctcactact acagatagcg aaaaaaaggt agtacagcca caacaaaaag
    11341 actactatac tgaattgtta gaccaatgga acagtattat cgcaggcaac gatgcttatg
    11401 ataaaaccaa tcctgacatg gtcacttttc ataataaagc tgaaaaggat gctcaaaaca
    11461 ttattaaaag ctatcaaggg cctgaccacg aaaatagaac ttgcctttgg gaacatgcaa
    11521 aggattattc cgcttctact aatatcacga aaacttaccg caatattgaa aaaatagcaa
    11581 aacagatcac taatcctgaa tcatgctatt atcaagatag taaagctatt gctattgtaa
    11641 aagacggtat ggccttcatg tatgaacacg cttataatct agatcgtgaa aatcatcaaa
    11701 caactggaaa agaaaacaaa gaaaattggt gggtttatga aattggaact cctcgtgcta
    11761 ttaataatac cttatccttg atgtatcctt attttactca agaagaaatt cttaaataca
    11821 cagctccaat cgaaaaattt gtgcctgacc ctactcgttt tagggttcgc gctgccaatt
    11881 tttcaccttt tgaagccaat agcggaaatt taattgatat ggggcgtgtt aaactcattt
    11941 ccggtattct tcgtaaagat gatctcgaaa ttagtgatac aatcaaagca attgagaaag
    12001 ttttcacgct agttgacgaa ggaaatggtt tttaccaaga cggttcttta attgatcacg
    12061 tggttactaa cgctcaaagt ccactttata aaaaaggcat tgcttacact ggagcttacg
    12121 gtaatgtgct tatagatggc ttatcgcaat taattcctat tattcaaaaa acaaagtctc
    12181 ctatagaagc ggataaaatg gctactatct atcattggat taaccattct tttttcccta
    12241 tcatcgttcg tggagaaatg atggatatga ctcgagggcg ttctatcagt cgttttaatg
    12301 cccaatctca tgttgctggc attgaagcac ttcgtgctat tttacgtatt gctgacatgt
    12361 ctgaagagcc tcaccgtttg gcacttaaaa cacgtataaa aacactcgtc acacaaggga
    12421 atgcttttta caatgtctat gataatttga aatcctatca cgatatcaaa cttatgaagg
    12481 aactactaag tgatactttt gttccagtcc aaaaacttga tagttacgta gctagtttca
    12541 atagtatgga taaattggca ctatataata ataaacacga ttttgctttt ggcctatcaa
    12601 tgttttcgaa tcgaactcaa aattatgaag ctatgaataa tgaaaatctt catggctggt
    12661 ttacttctga tggaatgttt tacctataca ataacgattt aggacactac agtgaaaact
    12721 attgggcaac ggtaaatccc taccgcttac ctggaaccac agaaactgag caaaaaccac
    12781 tagagggaac tcctgagaat attaaaacga actatcaaca agttggcatg actagtctct
    12841 ctgatgacgc ttttgttgca agtaaaaaac ttaataacac aagtgctcta gctgctatga
    12901 ccttcactaa ttggaataaa agcctcactc tcaataaagg gtggtttatc ttaggaaaca
    12961 aaataatctt tgttggtagc aatatcaaaa accaatcatc tcacaaggcg tatacaacta
    13021 ttgaacaacg aaaagaaaat caaaagcacc cttactgttc ttatgttaac aatcaacccg
    13081 ttgacttgaa taatcagcta gttgatttta caaacactaa aagtattttc cttgaaagtg
    13141 atgatcccgc tcaaaatatt ggttactact tcttcaagcc aacaacactt agcataagta
    13201 aggcacttca aacagggaaa tggcaaaaca taaaagctga tgacaaatca ccagaagcca
    13261 tcaaagaagt ttcaaatacc tttatcacta tcatgcaaaa ccatactcaa gagggcgatc
    13321 gttatgctta tatgatgctt ccaaatatga ctcgtcaaga atttgaaacc tatattagca
    13381 agcttgatat cgacttgtta gaaaacaatg acaaactggc cgctgtctac gatcatgata
    13441 gtcaacagat gcacgtcatt cactatgaaa aaaaagcaac gacgttttca aatcataatc
    13501 tttctcatca aggcttttat agttttcctc atcctgtcaa gcaaaatcag caataaaagc
    13561 ttgctcatca aggaattgca gctaaaaaca atactcttaa ctctcataaa attccccaca
    13621 aaagacaacg acgcttaccg catactgggt atcagtcctc ctcattagaa ttcttaggtg
    13681 gagctttagt tgcttctttt aaccatatca caaaaccctt tcgtaagaaa gacttaagga
    13741 tttagctgtt attggaaagt aagggttaac aatgaaacgt tattaaaaac aaaaaaactg
    13801 gaaactgcac tgagccccaa aagttggcta ctctatttga agtaaaggac ttagttctgt
    13861 attgtagaga actaagtcct tttcgtttta ttttgatacg tttattggtg caataatcga
    13921 tgataatagt aggtagaacg agtcacttta gccgtcctta aaagaaaatc taatcagaac
    13981 tcgtctttgt ccattcttta taatggtttt ttgtcttctt cttttcagag atgcttcttt
    14041 caaacggagt tccctcagtt tttttagcgc taaatgtcta gcttatcttc atagcttaat
    14101 gtcatacaaa aacaccccaa acgttagatt tttttatcta acgtttgggg tgcagttcat
    14161 agttgtgcta gtcttttttg tgatctgtta tgtgatgata tttttcatta gttaataaga
    14221 caaagacgtt ttacttacgt tttggtgggt tatggatagc ttcgccaagc acatctgcaa
    14281 aggcttcgta catcacttca gagaaagttg ggtgtccatg aattgataat aacaattcat
    14341 caacggttaa ttcagattcc ataatagtag ctgcttcatt aatcatctca gctgcagctg
    14401 gaccaataat gtgtacacct agaatttcgt gatatttggc atcagcaata actttgacaa
    14461 aaccatgggc ttcatttgaa gcaatcgcgc gtccattacc agtaaagctg tttttaccaa
    14521 taagcacatc accatattgt tcacgcgctt gttcttcagt taaaccaacc attgccactt
    14581 cagggtgtgt gtaaacagct gctggagtgt atttaaggtt agctttacga gttgtgttgc
    14641 catgcatcgc attttctgca gccacttcac ccatacggta agcagcgtga gcaagcattt
    14701 tcgttccgtt aacgtcacct ggcgcataga tacctggaat tgatgtctct tggtagtcat
    14761 taactttgat acggttacga tccatttcaa ggttaagatt ttccagaccg ttcatttgtg
    14821 gtacacgacc gatagaaaga agagcttttt cagcgacaac ttcttcacca ttgttaagtt
    14881 tcaaggtcaa ttggttattt gcttcaacaa tttcagagac accaacagat gttttgatct
    14941 tcatgccttt cttagaaagg attttttgaa gttcaagaga gacttcctta tccatagctg
    15001 ggataatgcg gtcagccatt tcaataacgg taacatcaac accgtaagat gcccaaacaa
    15061 gtccaagctc gataccaaca acaccaccgc ccataactgc tagtgatttt ggcatttcac
    15121 gaaggtcaag gatatcgtca gacgttaaga caagtttaga gtcaattcct gggatattga
    15181 tacgtgatac tttagaacct gtagcaagga taacgttgcg acccttaatg gtttgtgacc
    15241 caatggttac agtcttatca gggttgactt gaccaagccc attaaagatc gtgactttat
    15301 tagcttttag aagaccttga acaccacctg ttaaggtttt aacaacggtg tttttaaagt
    15361 caactgtttt gtccatgtca attgtatagt tagttgaggc aaggttaatc ccacgtcctg
    15421 ctgcaatctt aataccatca aggatttcag catttttaag gtaagttttg gttgggatac
    15481 accctacgtt caagcaagtt ccaccaaatt cagatttctc aacgatggca attttaccac
    15541 caagttgagc accacgaata gctgcataat aacctgcagg gccaccacca acaacgatga
    15601 tgtcatactc atcatcagca agtgcagctt ttggtgcagc tgaagcagct tgagctggtg
    15661 cttttggcac ttcaagtcca gcagcttcta aatcttctgt tgtacgagca acattcacat
    15721 ctgaagcagc tgggctagaa acctcaacag attcaccttc agcaccgatg taaccgataa
    15781 cttctgttac aggtactgtt tcaccggctt gacgtgtaat tttgagaaga acacctgagt
    15841 cttctgcttc aagttccata ttggttttat ctgacatgat ttcaagaaga atatcgcctt
    15901 cattgacagt atcaccttct tgttttttcc actcgatgat ttcaccttct gccatgtcaa
    15961 caccgagttt cggcataata atttcaacag ccataattta agataccaag agcgaggaga
    16021 aagcgattga atttttgcgg taagtcagaa atctttgatt tcgttgacgc actcacgtca
    16081 ggacaactag gactttccga aacaaaaatt gaggaaagtt cagacgtcta cgacgctaag
    16141 attagccaac tcttaccact tttatccgag ctttccgctc gggttcaatt gcttatcact
    16201 catttgcatg agatctcctc gttctacatc ctttctatat ttttgagaaa agggcaccaa
    16261 gcctaaactt agtaaaatcc cttttattat tcaatgcttt tcttgtttaa aactgattga
    16321 tcagattaac aattcaaatg gattttccat caatttcttg aggtcaacca tgaattttgc
    16381 accgttcata ccgtctacca agcgatggtc gatggttaag cacatcgcca taattgggcg
    16441 ggcaacaatc tcaccatcca caaccgttgg agttgggata gttgctccaa caccaagaat
    16501 tgctgagttt ggttggttaa taattgggtt aaatgtcttc gtaccaaaca ttcccaagtt
    16561 tgtgattgag aaggttgatc cagacatttc agctgctttc aacttaccag tttgcgcttt
    16621 tttaatcaca tcttttgaag caagcacgaa atctgacaag ctcatcttat ctgcaccatg
    16681 gataactgga acaataagac catcatcaag acctacggca atacccaggt tcacaaagcg
    16741 gtgcaattca atatcattag cgttattgat gagggaagca ttcatgtact catgctcagg
    16801 tttcatcaac gttttaacca ctgccatacc aatcaagtct gtgaagctga ctttaaggcc
    16861 tgttttagcc atgattgggt caattaactt cttacgaagg gcaatcatct ctgtcatgtc
    16921 aatatcgtag ttaagcgtaa aggtaggggc agtaaggtaa gagtttgtca tacctttaga
    16981 gattgcctta cgcatagctg acattggctt gtgttccaca ccttctggaa gatcaacaac
    17041 tttttcttct ttagctgctg gggcttttgc ttcagctggt ttagccgctt caagaatagc
    17101 catgatgtct tctttcatga ccttaccgtt aaagccagta cctgatacgg ttgccaaatc
    17161 aatacctttg tctgctgcaa ttttacgagc aagtggtgaa gctgtcggtt gagcaccttt
    17221 aaagttttca acgtcttctt tatggacacg tccttttggt cctgttcctg gaacttggcc
    17281 aaggtcaatg cccatttctg ctgctgcctt acgtgcagct ggagtagcac gaacttttcc
    17341 gccatttcct tgcggaatag ctgtcgctgc cacttgagga gctggacttg ccacattttc
    17401 ttttggagca actgctggtc cagcgtctgc tgaagcagga actggaattt ctgttgtttt
    17461 ttcacttgaa gcaatagtat ctactgattc accctctgca ccaatgtaac cgataacttc
    17521 agttacaggt acagtatcac cagctggacg gacaattttc aatagcacac ctgagtcttc
    17581 tgcctcaagt tccatattgg ttttgtctga catgatttca agaaggatat caccttcatt
    17641 gacggtatta ccttcttgtt ttttccactc gatgatctcg ccttcttgca tgtcaacgcc
    17701 cagctttggc ataataattt caaatgccat ttctacatcc tttcacgatt tgataagcgc
    17761 catcaacatc ctcaccttgc tacgaaaaca tacgaaaggt gaggtgccgc gacacgggat
    17821 aagacaactc agttcttcta aaaactttca aaatagtttt tagctgagac gttactgata
    17881 aacatagcct ttatcagatc acttgcctta tcttctagtt gcctttgttt gccattttca
    17941 caatagcagc tttgattttc tcaacgtctg gtaagatcgc ttgttcaagt acacgtgcat
    18001 aaggtactgg aacatcttca cttgcaagac gaacgattgg atgatcaagg taatcaaagg
    18061 cttcactttc ggtaatcatg gttgcaattt ccccaatgaa tccaccggtc ttgtaggcat
    18121 cgttgacaag catcaattta cctgttttct taacagattc aataatcaac tctttatcaa
    18181 gtgggatgag ggtacgtggg tcaacaactt caacgttaat accatccgct gctacttctt
    18241 cagccgcttg aagaacacgc tccaacatac gaccatatga cacaattgtc aaatcagttc
    18301 cttcacgttt gatgtcacct ttgccaagtg ggatatagaa gtcaggatct tggttaactt
    18361 cttctttttt accataaagc gcttttggtt ccatgaaaag aacaatgtta ttatcacgga
    18421 tagctgattt taataagcct ttagcatcgt tggcattacc aggagcaaca actttgattc
    18481 ctggaatgtg agtcaaccat gcctcaagag attgtgagtg ttgcgcagcg gaaccaatac
    18541 cagaacctga tgccacacgg aaggttacag gggtaataag gcctccaccg aacatgtaat
    18601 tatttttagc accattattc acgatagcgt ccatcatgat ggtaaggaaa tccatgaagg
    18661 taacgtcgat aattggacgt agtcctgtaa tagctgcacc aatagccgca ccagagatag
    18721 cagcttctga aattggggta tctttaacac gtttagggcc aaattcttca atcattccaa
    18781 cagaagtccc aaagtctcct ccgtaaaccc ctacgtcttc tcccataagg aaaatgtttt
    18841 cgtccttgcg catttcctca gtcatagcaa ggttgactgc ttcacgcaaa gccattaatt
    18901 ttgtttctga catcattttt atttctccat ttattattca aatacgattg cttcttactg
    18961 acaaggtgat cttagtcaac ccaaacgtct tcgaaggcta ctgaaagttc tggatctgga
    19021 ctgttttgtg caaattcata agcatcgtca acttcttttt tgacttgtgc ttgaatagca
    19081 tccaattcgt catcagtggc aatgccttcg cttgtcagat aagtacgata tttgatcatt
    19141 ggatcttttt ctttccactc atccacttct tctttagtac ggtatttacc agcatctgca
    19201 gtcgagtgac caaaccaacg gtatgattct acctcaacaa tagctggacc atttccacca
    19261 cgaacatgtt caacggcttt gcccattgtt tcatagacag ccatcacgtc attgccatct
    19321 tcacagtaga aaccaggaat tccgtaagct tctgcacgtg tgtataagtg tggtgtattt
    19381 gttgcattat tgatgctcat tgaaattcca taacggttgt tgatgatgaa gaaaataaca
    19441 ggaagtttcc atgttgcagc catattaaca gactcgtgga atgatccttc gttagtagcg
    19501 ccatcacctg agaaagcaac agctatattg ttagttcctt tgtattgttg agtgagggca
    19561 gcaccaactg caagggcgta accaccgcca acgataccat tggtaccata gtttcctttt
    19621 tcaaaatcag ccaagtgcat tgagccacca cgccctttag acacaccagt tgctttacca
    19681 gcaagctcag ccatcatttt attaaggtcc atgtctttag cgattgattg tccatgtcca
    19741 cggtgatttg aaaaaataat gtcatcgtaa gacaagtgag ccaccgctcc aacattggct
    19801 gcttcttcac caactgagaa gtgagtcatc ccttgtacaa atccacgacg gacgagttta
    19861 ttaatacgtg aatcaaattc acgaatacgt tccattttaa ggaacatatc caaatgttgt
    19921 tctttagaaa ctgttaccat ttcggcctcc atattatcat attacctttt tatgataaaa
    19981 ctttttttca caatttgcaa ataattaaat cgctttctac cttaccttat ttggtttttt
    20041 agaaatgcaa tagtttgtga aattacaaac aaaactgtac taaaaaattt aaaaatacta
    20101 tataacagtt tcacgtttta ccgaccttga cataaaaaac acatcatttt aaaacctctt
    20161 tcacaccttc aaacaagtag caaagcaata aaaataagct tagcaaaact gctaaagctt
    20221 atttttatga ttctatttgt tcagcgatgg tttcccattc ttccataaga gcttcttgtt
    20281 cttgatccaa ttggtcccat tccttttgcc aagcgattaa ctgcgccgta tcattggagg
    20341 catgcatgtc ttcttgaata gcaccaatac gctcttcaat ggtttcaagt cttgcttcaa
    20401 tctcctcata tcggcgggtc aagcgacgac gctctttttg attagctttt tgtagctgat
    20461 aatcagtggc agaggcttct tttgtttcct caactgtctc tcctgctgct aggcgggcta
    20521 attcttctag ctctgccttt ttctcaaggt aataatcata gtcacctaag taaagggttg
    20581 agccattttc ggtaatttcc aaaaccttag ttgccaaacg attaatgaaa tagcggtcgt
    20641 ggctgacaaa aagcaaggta ccgtcaaagt caatgagggc attctctagc acttctttac
    20701 tgtcaatgtc taggtggtta gtcggctcgt ccagaacaag aaaattattg ttttccatag
    20761 ataacttcgc aagaagcaga cgggcttttt ctccacctga cagcatagcc accgattttt
    20821 tgacatcatc tccagaaaag agaaaagccc ctaatcggtt tctgatatcg acttctggcg
    20881 tagttgaaaa gtcctgccat aattcttcca aaaccgtatt gcttggcgtc aaatgtgatt
    20941 gggtttggtc atagtaacct atttcaacat tagcaccgta tttcacttct cctttgatga
    21001 aaggaatctg tccaataaca gatttaatca gagtggattt accaatacca tttggaccaa
    21061 caatagcaat cgcatctaat ttgtgaacgt ctaggttaat aggctcagat aagacatgtt
    21121 ggttataacc aatagcagct ttttcaaccg tcaacaccac attgccagac ggcttatctg
    21181 cctgaaaagt catgtgggct gattttctag cactagtcgg tttgtctaag cgttctattt
    21241 tttccaattg cttacgtctc gcctgagcac gttttgtagt tgaagccctg acaatatttt
    21301 tttgaacaaa atcttctaac ttggcaattt ctttttgctg tttgtcaaac tgcttttctt
    21361 cggctactaa tttttcagct tttaaggtca taaaacgaga ataattgcca acgtagcgat
    21421 ccaatccatg aggagttaaa tccaaggtca ctgttgccac cttatccaaa aaataacggt
    21481 cgtgactcac aatgattaga gctccttgat aattggccaa gtagttctct aaccaggcaa
    21541 tggtttcaat atctaagtgg tttgttggct catcaaggac caatagttct ggcttttcta
    21601 aaagcatttt agccaaggcc agacgagtgt tttgaccccc tgacagctca gcgatagtca
    21661 tctgccacat gctctcatca aacttaaacc catttaaaat ggctttgatg tcagattcat
    21721 acgtaaagcc gccttgctga cgaaaatgct ctgtaagcag atcataatct gtcatcagtc
    21781 gggttaaatc ttgacctgaa acggttgcca tatccatttc catctgacgc aggcgctttt
    21841 catcttggcg taatgcttcg aaaaccttga gcatttcctc atatattgtt tgatctgatt
    21901 caaaacggct attttgagcc agataagata aggttaggtc ttttttagta ttaacttctc
    21961 cgctcgttgg ggtttcttcc ccaaccaata attttagtaa agtcgacttg ccagctccat
    22021 taggaccaac caaggcaatg cggtcacgtt catcaacttg cagtgatatg ttttgaaaaa
    22081 gaacatctcc tgagaaagag cgttctaact tgtttccttg taaaataatc atactttcat
    22141 tctaacaaaa aaatgccctt ttgaggacat tttcagccta gtttccaaaa gaaatcgaac
    22201 tctttttaag tcgttgatta ccttctttag cgctaacaag gaaagtggaa tgactattac
    22261 cactcccatg acgcatcttt gcagatggct tttgtgttaa gatatcaaaa atttgcacca
    22321 cttgctcagt aactatcgag atcttattgg ctaaaacgga atcactgtga ttagaatagt
    22381 acatcagccc tataataata attgttacta ataagatagt ttgtaaaaac cctttgataa
    22441 gatgccaaaa cattttcact attagcttag gcagccacaa aatgatcgcc agtaattgtt
    22501 tcatttgtca cctcatgttg tactaggaaa tggttaagac aacctttctt ctttttggta
    22561 gtttatcggt aaccactcta acaggacttc taattgctgg ttccaatagt accactcatg
    22621 tttaccatga cttttatgat aatcaatgtc aagaccttga gcctgaaaat catcaatagc
    22681 tttttcatta gtggcaaaaa gaaaatcctc atagccacac caagcataaa atttggtttt
    22741 tccatcactt tctgccacca tatttttaag gtaatgctta tcaaggtcag ggtcatcaaa
    22801 ctggccaaaa acgccctgcc aataggctaa ttctcccagg tttccctcaa gcaaggtctc
    22861 aggagaaaaa tccaaagcgc ctgaaaacga tgccgcataa gaaaaccgat tgcttttgag
    22921 tgcccactta aaggcaccat agccacccat agagagccca gcaacaaagg ttttttctcg
    22981 tttctgggtc atattaggaa agaaagctgc taagacctgc ggtaactctt gtgacaacgc
    23041 acgataatag ttaagtccat aagccgtgtc tgtataccaa cctaggtctg tcgaaggcat
    23101 aacgactatc aaattggtat gccgcaacaa gcgttcaata gctgttcgtt tttgccaaga
    23161 gttttcattg cctcccatac catgtaacaa atataaaaca ggaatatcct tatccccttg
    23221 atctttttta gggatttcag actggtcagg ataaatcaca tttaccttac gctccattcc
    23281 taaaactacc gaatggtatt caattgcaat atttgccatt cattacactc ctttatacca
    23341 aaataatcct atcacgtaaa tctactgtat ttttgggtga acagtttcct ggtttaccag
    23401 ttgttaaaat caaagaaggt aggcagtttt tgcctaacct tcctattttc actaacgaac
    23461 ttccatcaca accggcagaa tcgctgggcg ccttttggtt tgttcaaata agaatttaga
    23521 caaatcatct ctgacattcc cttttaattc gccccagtca aaggtatctt ttttaaagta
    23581 attgccaaca gttgtattaa ctaattctgc actttctctt aaaatatcat gacttttctt
    23641 gacatacaca aatccacgcg tattaacttt agccttagaa ataatgcgtt tttctttttt
    23701 agaaacagta atagcaacaa tgaaaatacc atcttctgac aagactttac ggtctcgtaa
    23761 aacgatatta cccacatcac cgatagcatt accgtcaatc atgacatcac tggcaggtac
    23821 acctccttca tggagaaaac cttcgtcatt aagcaccatg atatcgccac gcttcagaat
    23881 atgaatattc tctggaaaaa taccaacttc ttcagctagc tttgcatggg cagctaaatc
    23941 acgatattct ccttgtactg gaaaaagata ctggggtttt aacaaattca tcaatagttg
    24001 caaatcacgc ccgttagcat ggcctgacac gcgtaagttt tgagtgatta atttaacaga
    24061 accaccggcc ttgtaaatca agttttcaac acgcgccacc atagcttctt tagccgtact
    24121 tggtgttgtt acaatataaa caaggtctcc ttctttgatt tgaacataac ggtgacgtcc
    24181 cgctgccatt ttttgtaagc tattaattgg ctcacccata cgaccagctt caaggatgat
    24241 taattcatgg tcttcgaatt tagacatatc cttaggttta attaaaagac gctcatccgt
    24301 aatcattaat ttttctagac gtaaagctgt tctgacaata ttttctgcat ctgttccggt
    24361 taaaacaaca cgacgcccat gggcagtggc ggaatcaaat acttgctgaa tccgaacaag
    24421 atttgaggct actgcagcta caatgacacg gccatcagca tcagagataa cactgtccat
    24481 ttcttcacca acttcagatt cgctggcaat ctgatcgttg cttgtcgcat tgactgaatc
    24541 tgataaaaga gctagaaccc cttctttccc aatctcagct aaacgtagca aatccgtctg
    24601 ataaccttct cttgctgctt gatcaaattt gaagtcaccg gtataaacaa tgtttccttt
    24661 atctgttcca ataacaatac ccatactttc tgggattgaa tgcgttgttc taaagaacga
    24721 aactaggcca tctttaaatt caatttcagt atcactgtct accacatgaa aattattaaa
    24781 tttcttagtg ctgttattac ttttcacaaa tagcttggct aattcaatag tcaattcaga
    24841 tccaaataca ggagctgata cttcagctaa caaataagga agggctccaa tggcgtcagc
    24901 atggccatga ctcaagaaaa tcccttgtac tttacctttg ttttcaatta cataatctaa
    24961 attggggatg actaaatcta ccccaagttg ctcattttca gggtacttga gccctgcgtc
    25021 taaaataaac atagaatcgt taatttctac caaatagaag ttttttccgt attcacggac
    25081 ccctcccaag gcaatcattt taatatcagt catgatactc ctttaaatat tttattatta
    25141 caaacggtcc ttacaacgta agtcgaatta ctgttatgta gctatgctac tatcttctat
    25201 agtatatcat atttgaggag ttttttctct aaatagcctt gatactttca gattattttc
    25261 agtatggaaa tcaaaaaatc actgacttat tattagtcaa tgatttagat cgttgattaa
    25321 tcaaatagtt ggtaatagtc agtaatcgtc agttgttctt tttccatttg atttaaatct
    25381 ttaataatgt ttccatcttt cattacaatc agacgattcc cataagttaa tgcatcttcc
    25441 atatggtggg taatcatcaa agctgttaag ccatcttttg tcacaaactc atctgtcaat
    25501 tgcattaaag agtgactcgt cttagggtca agggcagccg tatgctcatc taataataag
    25561 agagctggct ttttcaacgt tgccattaat aaacttaaag cctgtctttg tccaccagac
    25621 aaaagacctg ctggtgtttc taaatgtttt tctaggccat ttcctgttcg tttaaccaaa
    25681 tcctcaaaac tagctaagtg ctctgttatt tttcgagaag ccaaggagcg tttttctcct
    25741 ctttgacgtg cgattaagag attttcagcc actgtcatcc gaggggctgt tcccattttg
    25801 ggatcttgaa agactcgcga taggtaaaga gctctttttt ctgctggcca atgcgtcaca
    25861 tcctgaccaa gaatcctaat ttgcccccgt gtcaaactta gcgttcctgc aattacatta
    25921 aaaagggttg attttccagc tccatttcct cctaaaatag ttaaaaaatc atgttcatag
    25981 atagttagtg tcacattgtc caatattgtt ttagcatctt caaaaccatt atctacgtca
    26041 actgttgcat tgatcaattc aataattttt gtcatcgtgt taacctcact cccttaaaga
    26101 agcgctcttt taccactggt atcatgaggc acagtgctaa aacaagagca ctaattaatt
    26161 tcaaataact tgtattaaaa cctagcgtaa taactactga aattaaaaat tgataaagaa
    26221 tcgagcctat tacaatagca atcaaacgtt ctaaaagagt cagtccagtt gagtatagta
    26281 cttcaccaac aattatgctc gccaaaccaa taacaataac tccaatccct tttgagacat
    26341 ctgcatagcc atcttgttga ctcactagag cacctgataa agctattaaa ctattagaaa
    26401 ccacaagtcc cataacttcc atccaatccg tgttaatacc aaaactctta gccatatctt
    26461 tattgtctcc cgtagcgata taagcttgac ctagattagt gtaaaggaaa tagatcaaaa
    26521 cgctaataac aatcacaaca gttatcagac ctgttaaaag gctatttaaa tcaattgaaa
    26581 aaggtaaaca atcctgaata cgtttatgat catgtaaacc caagtttgct cttcccatta
    26641 ccattagcat aatggagtta catgacgtca tcaccaaaat tccagctaaa agtgttggca
    26701 tttttccttt cgtatataac agccctgtta aaaaacctgc taaagcacct gataacatac
    26761 caagtaaggt tgatagaaat ggattccacc ctaagctaat agcggtgacc gcaacagctc
    26821 ctcctaaagg aaaagaacct tctgtagtca tgtcagggaa gtttaaaatc ctaaaggtca
    26881 ggtagattcc taatcctaaa actccccata taagaccttg tgaaactgat gaaataatca
    26941 tatttttcct catatttata ttagcgggta acgctcgcca gtataaaccc tttctttaca
    27001 ttaattttta gatttgtttt atacttagtt cagcaccgtg gcttagtctt tttttcaatc
    27061 actttgacga aactaagaca gaaaacaaaa aagtcgagaa tcatgtttaa acttactcaa
    27121 aaggcaagat tttttacgtg tctaaaatag agcattttaa aactaaaaat gataaaaata
    27181 accgttacat cctcaagacg attgtctgac ttggcatcca aattcatctc agtgagggtg
    27241 ttttttatga ttttttcttg accttttata tcacacgtct ttgtattaat tctcaataaa
    27301 agaagctgaa ggaaaatctt ccctgttaat agcaatacct aattctgctg ctacattctt
    27361 attaattagc ggttgaccaa tatccacaac tttgacagga acatctacaa cacgctttcc
    27421 tttgattaat tttaacacct gattagctgt ttgaactccc aaatcgtact gattttgaga
    27481 aatagctgcc aaaccacctt tttcaaccat tcgatcaacg ctagtgtaga caggaatctt
    27541 tgcagcctta ctggttgtca tgactgatga aaatgcactt gctatagtat tgtcttgggg
    27601 gataaatacc gcgtctactt tacctaacat aactgacatc gtggcaggaa cttcgttagt
    27661 agaaggaacc gcatatgaaa taacttgata gccctttttg cgagctaacc gcctaaactc
    27721 tttaacttga gataaggaat tatcctcatt acttgcatat aaaattccaa ctgttttgac
    27781 atgtggtgtc agctttttca ttaaatcaat tgtctgttta acaggcactt tattagatag
    27841 accagttaca ttagcttcag gttgatccaa ttgcatcact aatctagatc ctactggatc
    27901 agatactgct gacatgacaa ctgggatatc cttgctggca gctgctaagc cttgcgccgc
    27961 cggggttgcg ataccaatca cgatatcact tcctgattgc actaattgcc tactcattgt
    28021 ttggatttta ctctgatccc cctcagcatt cataacctta atcactacat tttgtttttg
    28081 aggcatctgc tttttgagtt gatcttcaat acctcgctta atatcatcaa gagcctcatg
    28141 agtaacgaat tgtaagatgc caattgtaat gtttggttgg ttagccaaat cacggttttc
    28201 ctttgatact ccttttgata atagagagcc tatcactatt acagttaaaa caaggagggt
    28261 agctattaaa ctcttgtttt tcatctgaat tcctcacatt tcatgtcaat ctctttaaaa
    28321 cgttgatgat gagaatactt ctcaaaagaa aaagcactta gtaatgatta ctaggcgctc
    28381 ttgtgaaatc caatgtcagc gcatagatat ctttttagaa gtactctaaa agtcgtatct
    28441 atgccaattc ataaacacaa cttatctatg ccagctttgc caatttgcta agtgttgtgt
    28501 ttttaccatc attgacttcc tttctcgttt ttttaacatt ataacctaaa tcaaaaaaat
    28561 tgcaagctct ttcgtccata tttttagtca agtatttgtg gtataatgaa gagattagaa
    28621 ttcagaaagg agaaaccatg tcttttgacg gctttttctt acaccattta accaacgaat
    28681 taaaagagaa cttgctttac ggtcgtatcc aaaaggtcaa tcaacccttt gaacgggaac
    28741 ttgtcttaac cattcgtaac catcgcaaga attataaatt gctattgtct gcccatccta
    28801 tttttggacg acttcaaatt acccaagcgg actttcaaaa tcctcaggta cctaatacct
    28861 ttaccatgat tatgcgtaaa tacctccagg gtgcagtcat tgagcagtta gaacagattg
    28921 ataatgaccg cattatcgaa atcaaggtat ctaataaaaa tgaaatcgga gatgctattc
    28981 aggcaaccct aatcattgaa atcatgggga agcacagtaa tatcatcttg gtggaccgtg
    29041 cagaaaataa aatcatcgaa tccattaaac atgttggctt ttcacaaaac tcttaccgca
    29101 ccattttacc tggctctacc tacattgagc ctcctaaaac agctgctgtt aatcctttta
    29161 caattacaga tgttcctcta tttgaaatcc tccaaacaca agaactaaca gttaaaagct
    29221 tgcaacagca ttttcaaggc ttagggcgag acaccgcaaa agaattggcc gagcttctga
    29281 ccacagacaa attaaaacgg ttccgtgagt tttttgctag acctactcag gcaaatctga
    29341 ccacagcttc ttttgcgcct gttcttttct cagatagcca tgcgacgttt gagactttgt
    29401 ctgacatgct tgaccacttt tatcaagata aggctgagcg tgaccgtatc aatcagcaag
    29461 ccagtgattt gattcaccgt gtgcaaactg aactggacaa aaatcgcaac aagctaagta
    29521 aacaagaagc tgagctgcta gccactgaaa atgctgaatt attccgtcaa aagggggagc
    29581 tgttaaccac ttacctgagt atggttccta ataaccaaga ctccgtggta ttagacaatt
    29641 attacacggg tgaaaagctt gagattgcct tagacaaggc tctgacacca aatcaaaatg
    29701 ctcaacgtta ttttaaaaaa taccaaaagc taaaagaagc tgtcaaacac ttatctggat
    29761 tgattgccga taccaagcaa agtattactt actttgagag cgtggactac aatttatctc
    29821 aagcaagtat cgacgacatc gaagatattc gcgaagaatt atatcaggct ggctttttga
    29881 aaagtcgcca aagagacaaa cgccataaac gtaaaaagcc tgagcagtac ctggcttcag
    29941 atggaaaaac cattctcatg gtgggacgca ataacttgca aaatgaagaa ctcaccttta
    30001 aaatggctaa aaaaggagaa ctctggttcc atgctaagga tatccctgga agtcatgtca
    30061 tcatcaaaga caatcttgac ccaagtgacg aggttaaaac tgatgctgcc gaactagctg
    30121 cttattattc gaaagctagg ttatcaaatc tcgttcaggt cgatatgatt gaagctaaaa
    30181 aattacacaa acctagtggc gccaagccag gatttgtgac ttatactggt caaaaaacct
    30241 tacgggttac tcctgaccaa gccaaaattc tctctatgaa attatcctga taagcaacta
    30301 aaaaacagct ctcctaggaa agttatttcc cctaggagaa ctgttttttt attctgattg
    30361 ttggtgcttg atatggtcaa gaaagtcttg catattcaca tcatcaggca cttgtctgag
    30421 gtaagcggta gccatttgga tagccttatg aaactggcca aactccctta ataaataggc
    30481 ataatcctgt aaaaactctg gattttctgc caaatcagcc gaaatctcat tataaagagc
    30541 caaggcaact tcttcttgtt ccaaggcgtg gtaagccttt gcaatggtcc atttggttaa
    30601 gacattatca atcgtctcac gattaagagc aataacctcc tcaaaacgct cggcatcaaa
    30661 ataaagggtc gctaaacgca tgaaaatctc ttcgtcatca acagctactt cctttgcttg
    30721 aagcaggtaa ttttcagcat tctgcctatc gtgtaattca taagaaagct gcgatgctag
    30781 taataataat tgactgtcaa atgcattttt acgtaggccc tgttgaacca agcgcaaagc
    30841 ttctgacgtc ttatgttctt catgaagact caaagcataa ccatattcat aacctggata
    30901 atctggattg atggtttcca actgtttaaa gtaaagattg gctttttgat aattttcttg
    30961 gtcatacatg agggtcgcca attcaaaaac agtttcatct tcgtattcaa tggccacggc
    31021 cttttccaag aattcgatgg ctgcctcaaa tttccctaag ctagcatagg ctcgtccaat
    31081 gcgttgataa gtggaaatac ctgtcaattc aaggatttga cgattgtcta actgtgcata
    31141 gtaatcaata gcttctttaa aatactgcaa ggacatgtca atttctgcca aaccaaaaat
    31201 gaccaatggc tctgggctga tgcccactgc ttgaagcaat ttttcacgcg ccacctctgt
    31261 cagtccttcc atgtcataga ggtcagccat tactaagaga gctgacaaat aattgaggct
    31321 atcttttgaa accttatcca aatacaagaa agcttcttca atggcgtcgt cttctgctgc
    31381 aatctgagct aaatttatat tgagttctgg gtaatcatca gctaactgca aataaatacg
    31441 cttggcatgt ggcaaaaaac ctatactttc taagtattct cctaaggcga ttaaactatc
    31501 tgcatcatct tcttttaaag ctttttggaa atatttttca gcgtgcgcta ggtcttgctg
    31561 atccaaggaa gcaatcattt tttcactatt taacatggtc cttaacctcc tcaatcacca
    31621 atacttcttc gtcatacaaa ccgctaactt ttttgtacca gtcaaataat tctttaatca
    31681 caactttgac agaagcgtag attgggatga caaggaaaac accccagaca ccaaacatag
    31741 agcccgcagt caataacaag aacataatgg taataggatg aatgctcagc ttatttccca
    31801 aaacaagcgg tgctacaaaa cgcccttcga tggtttgctc aatcataaag ataacaagca
    31861 ccttaaccaa cataaatggg ccttgtacca tagccataat cacaacaggt atcatggcaa
    31921 ggaaacttcc taagtaaggt atcatgttaa gaaagccagc aataatccca aaagtgatgg
    31981 catatttcag tcccacaagg ctaaacatga tagaaaacat aaagccgaca acaattgcaa
    32041 ccgtaacctg cccttggaca tagcctgata attgcttgtt aatatctccc aagactcgaa
    32101 ccataggcac ccgtaatttg agaggtaaga cattcacaag gccatttttc atgtggctac
    32161 tgtctcgtaa aaaataaaag agaataaagg gcgaaataat aatagccacg gtaatccgag
    32221 caatggcacc agcaaaatta ccagcccagt caatagcatt ttttgaaaaa ctttgcgcgt
    32281 aatccaaagc cttttgactt gtatgggtaa gcatgtcttg gagttggggc ttgtagctaa
    32341 ctaaccattc attttcaaga agtttattgg cttcttcatt gaccttgccc acatatttgg
    32401 gcaaatcctc aataaaactg gtaagttggg tctgtaccat gggaacaaag cctgaaatcg
    32461 cccagacaaa aagtaaggta atcaaaccaa aaacaataaa aatagaggtg gtacgattcg
    32521 ggcccaagtg attaataagg tcaactaagg gtttggtcag ataatacaga atggtcgaaa
    32581 taaccaaggg caacatgatg accgcaaaaa aagaaatcac tggcataaat aaaaaagaga
    32641 ttttagtaaa aacaaaaatc gttaaaaagg ctaaaagtgt tattactaaa gccatggtag
    32701 cttgattatt taaaaaccat ttgtaaaata agctatctgt tctagacttt tcaggtatta
    32761 agggcattaa gatagggttc ctttctttgg gaaaatgata agttttactg gtaacctggg
    32821 taaatcaata aaaggtcaca gatttatcca tgagttggtt gttttggtca taggtaaatt
    32881 tggcagagaa aaaaggacgg tcttctaaaa tccatttaaa aatgtcataa tcaccttccc
    32941 aagttggctt ttccaacact tgatcgtaag gtacccattc caaggttcct tctcgtgact
    33001 cttcatcgga aatgaggtct ccttcaaatc ctgttacttt aaaaacatag gtataccagt
    33061 catgaccagg ggtaaattct ggaaaagtaa tgattccttt aaaggccatc tctgtaacag
    33121 tcaaatgggt ttcctctaaa atctcacgac gggcacactc atctggggtc tcaccagcct
    33181 cgagcttacc cccaactgaa atccacttgc ctttgtggac atcattttct tttttattgc
    33241 ggtgtaataa tagcaaagaa tcgccattat caatgtaaca aatggttgct aattgagtca
    33301 tctatctctt tcctttccat ctttgtttct attataccaa tctctagaaa atatgctatc
    33361 attttatgag tcaaagtgtg aatacttagt cacgctcaaa accttctaaa gatgccttaa
    33421 aaaagtgtag ataagagcct acaatgaaaa acatcaattt aaactatcaa aagaaccttg
    33481 tcatatcaat tatcgttgat atgacaaggt tctttaatgt tttatttaat cacttcttga
    33541 gttttagcat acttggcttc tacagcatct ttttctgctt tccaccatgt ctcattttct
    33601 gtataccatt taatagtttc ttccaaacct tctgaaaagt ttgtaaattg tggttcccag
    33661 ccgagttctt cacgcaattt tgtagaatca atagcgtaac gaagatcgtg accagcacgg
    33721 tcagttacgt gatcataagc gtcttttggt tgacccattt tttcaagaat caattcaaga
    33781 acttccttgt tgtttttctc gccgtcggca ccaataaggt atgtttcacc gatacgaccc
    33841 ttagtcaaaa tagcccatac tcctgtagaa tgatcattag tatgaatcca gtcacggacg
    33901 tttttacctt caccataaag ttttggtttg attcctgcca agatatttgt aatttgacgt
    33961 ggaatgaatt tttcgatgtg ttggtatggt ccatagttat ttgaacagtt cgaaatggtc
    34021 gctttcacac cgaaggaacg tacccatgcc ttaacgataa ggtcagaagc tgccttagtt
    34081 gatgagtaag gtgatgatgg attgtatttt gtttcagcag tgaatttttc acctggtcct
    34141 tcaccctgtc ctggaaggtc ttcacgaagt ggaagatctc cataaacttc atcagttgac
    34201 acgtggtgga aacggatatc gtatttacga gctgcttcaa gcaaagtgta agttccgata
    34261 aagtttgtat ggataaatgg acttggatct tccaatgagt tatcgttgtg gctctcagcc
    34321 gcatagtgaa caatagcatc cgctttggca gccaatttat ctaccaattc agcgtcagcg
    34381 atatcaccaa caactaactc aacacgatca ccaagaatag cttcaatgtt agcacggtta
    34441 cctgcatatg tcaatttatc aaggacagtt acatgaacat ctgggtggtt attgtagaca
    34501 tagtgcacaa agttagatcc gatgaaacca gctccaccag ttacgataat atttttatac
    34561 ataagatata aagggacctt tcgtttccga aaaaatctat taaaagtaat gactctaaca
    34621 aagacgtttt aggcctaaga aaacatcgct ttctaagatt taagtcccat gttcagctca
    34681 aagagagaaa ctgaactttc ctttcatcat ttttagttgt tacttgttac cttgaagtag
    34741 agaagaataa ctcccctcat atccacctca aatgattaat cccaatcatc tgagtatgtt
    34801 gtttccctat aggtcttttg gtttcagtgg tttgacatca ctaagaagag gatggttttt
    34861 atctgcttca gaaacttctg cagctgctag attttcccaa gtaatcccaa gacttgggtc
    34921 agcatagttt acaaaagcat acttaggttt caagtcaaga gcccagtagt cattgacaag
    34981 ataactgtaa gagacagtct ctgaaagaac ttgaaagcca ttagcaaccc ctctaggaac
    35041 aaacattcct tttgaagcat caattactgt ctggtagacg tttccaaaag tctctccctc
    35101 acgaagatca acccatgctc ctaaaacctt gccatcatca gcaactgaga tgtatttatc
    35161 ccaaggttca gcatgaagtc cacgcagcac atgttgacgt gaaaaagaaa cgttgttttg
    35221 tagttttcct tcctcaaaaa aacgttctgg aaagccaatt ggcaacattt tttctttttg
    35281 gaaattttct ttaaaccagc cacgattatc cccacgaaca ggaatatcaa actctagtaa
    35341 gcctgggatt tctttgattt ctcggcaagc caatggtttg tcaaaaaaag tttctgtcat
    35401 taagcttctc caatcaaacg aagcaagtat tgcccgtatt cgtttttctt taaagattgc
    35461 gccaatttat ggacatcttc tttactgata taacccatgc gataggcaat ttcttccaga
    35521 tttgccactt gagcgttttg caagcgttga acagtttcaa tatattgagc cgcttcaagt
    35581 agactttcat gcgttccagt gtctagccat gcaaaaccac gccccatcaa ttcaacggag
    35641 aggtcaccac gatccaagta agccttgttg acgtctgtaa tttccaactc accacgcgcg
    35701 cttggtttaa tgtttttagc aatttctacc acgtcattgt catagaaata aagtccagtc
    35761 actgcaaagt gggacttagg cacttctggt ttttcttcga tagagatagc attcatgttc
    35821 tcatcaaatt ccaccactcc aaagcgctca gggtctttca cttgataacc aaaaacggtg
    35881 gctccttttt ctttggcagc tgccttttga agcattttag tgaggccatt accgtggtaa
    35941 atattatctc ctaaaataag agcaacacgg tcatcaccga taaactcctc tccaataatg
    36001 aaagcttgtg ctaaaccatc tgggcttggt tgttccttat aggataagct aatgccaaat
    36061 tctgacccat ctcctagcaa ttcttcgaaa cgaggaagat cttggggagt tgaaatgatt
    36121 aaaatatctt taatccctgc caacatcaag gttgacaatg ggtaataaat cattggtttg
    36181 tcataaatgg gcatcaactg tttagatgcg gcacgggtca gtggatacaa gcgtgtccct
    36241 gaacctcctg caagaataat acctttcata gtagtgctcc tattcttcta tataccctat
    36301 cattctatca ttttttgaaa gcagtgtcac gctttaccag cagaccgcaa aaggtaaggc
    36361 tcaggggaat agtcgctagg cgtcaaaagt ccttcgtgtc ctagcaataa ttgagctaat
    36421 tcatagccaa tcaaaggtcc aactgttaat cccgatgacc ctaaaccact agctgtataa
    36481 aggttcttca atcctggaac ctgaccataa aaaggagaat aatcactggt ataagctctt
    36541 attcctacac gacacgtttt ttgagtagct tcttttaata acggcaaata agtaagagct
    36601 tgcatttcaa gtttttctaa aatctgccaa tcaggctcca aatcataacc tttatcattt
    36661 tcgtgactcg caccaacaga aatcttacct tggttaaaag gaataagatc tatttcacct
    36721 tctggcataa caactggata attgtcgctg atgatgtgat gaatgtcata atccaagagt
    36781 tgtccctttt gtggtcgcac atcaacctga tagcctaaag gcctcaataa gtcaggtagc
    36841 catgctcctg ctgccagaat gacctgatca aaataatgac cagcaatctc ataaccactt
    36901 ccttgctgtt tcagagtgac tttttggcga ataactggat aaccactagc cttgagtaac
    36961 gtctcacata aagcggctcc ctccactcta gcagctcctg aagcgtacag acagttatca
    37021 aagccaacta agcctggaaa tgcctcctct tgtatctcct cacgtttttt tacttccaaa
    37081 tgaccgatta aagtggattc ttcttgtcta cttaaagcta attgataaag atcttttaac
    37141 ttctcctctt gcttttttaa taagtaaatc ccattttgct ggtaaaaatc cgttgcaaag
    37201 ccttcagtct gtaagtcgct gactaactct tgataaaaat cggctcctaa acgagccatg
    37261 cgataccaaa ctttattacg acgctttgaa aaccaaggac taataatacc agcagcagcc
    37321 ttagtggctt gtccttgacc atggtcaaaa atagtaactt ctttttgacc actttgttgt
    37381 aaataataag cggcggttga tcctacaatc cccgccccaa taatggctat tttcattcct
    37441 ggtatccttt tatcttattt taagacctta acagcctata aatggctaaa tggattggtc
    37501 gaggctttgc ttgaaataat gctgacatcc caaccgttct cttctttcca cccttggagt
    37561 ttctccttta atttctccgt aaaaagcacc tcaatatgat gccccgggtc aaccgcaaat
    37621 agtccttctg tcagcatctc ctgtgctgta tggtaataga tatcccctgt aatataaacg
    37681 tctgcgcctt tttgcacagc atcctgataa aattcaccac cacttccgcc acagatagca
    37741 atctttgaaa tcaaagggtt ttccttatcg taacggataa gtcgcacggt atctaaatca
    37801 aacacccttt tgaccttact tgctaactct tctaacgctt gttctttaac tgttccaata
    37861 cgaccaatgc caaagccttc tttggtttca gacaagtaag ttgcttcctt gatttctagc
    37921 agatcacaaa accaatcatt tagtccgcct ggtacaatgt caatattggt atggctcaca
    37981 tagacagaaa tgtcatgctt gaccaaatct agaaggatat cacgctgagg ggatgaaacc
    38041 agatctttaa gcggtttaaa gatgggagca tgcttagtta taatgagatc aacttcattt
    38101 ttgatggctt ctgctactgt tgactctcgg atatctaaag taatcataac cttacgaatg
    38161 tctttatcca atgaacccat ttgaagacct ttaacgtctc cttccataga taaatcaagt
    38221 gggcaaaagg cttcataggc atcaattagg gttttagctt tcatgaacaa tcacctcttt
    38281 tatttgttgt atttttgtca agagaagctg acgctcttga gttttttctt ctgggatgca
    38341 ggacaaggca taagctaact tatccatttc tcgttgccac ttctctttaa aaacgactga
    38401 tttttcctga gaaaggtatg gaccaaaacg caattctgtc gcggataaga ccttttcacc
    38461 atgctcagca acgatgattt cataatattt gtcattttca gccatgatag tttctgcaac
    38521 aattttaaaa gcgttaaccg ataaccaagc ccgtaaatca tcctcacgat tgttgggctg
    38581 taaaaccaga cgttcaatgc cctgcaattt ttccttacct gcctctaaaa tatcagcaat
    38641 caaacggcca cccatgccac aaatggtaat ggctgtcaca tcatcagctt cttcaaaggc
    38701 tgcaaggcca ttggctaagc gcacctgaat atgctcggca aggccagact gtgtgacatt
    38761 tttaagagca gattcgtagg gacctctaac cacttcgcca gcaatggctg ctgaaatctg
    38821 attagtttct accaaaaata tgggaagata ggcatgatca ctgccaacat ctaataattt
    38881 gacacctttt ggaacatagg ccgcaacttg ggctaaacgg tttgataatt gactatccat
    38941 cttgatttct ttctaaaacg taatggttct attatagcaa aattacctcc ataaaaaaag
    39001 aaaaccaaag gctaggcttt cgattttcca taagtatttt gatagtactt gcagtaagac
    39061 tgaacgggac aaatctcaca ttttggtttt ttggctaaac aatggtagcg tccaaagaaa
    39121 atcaatcgat ggtgagtaat aatccaatct ttctttggaa ttttagccat caaatctgct
    39181 tcaatctgct tgacatcggc atctgatgat gaaatattga gcctctttga gactctagcc
    39241 acatgagtat caaccgcaat agctggaaca ccataaacct ctgccagcac cacattggct
    39301 gtttttcggc caacacccgg taaactttca agctctttgt gggtttttgg cacttgaccc
    39361 ttaaaatcat cacgaatagc ctgagcagtt ttaatgatat ttttggcctt atttttatag
    39421 agtccaatcg ttctcagagc attttcaaca tcagaaagtt cagcaaaagc taagtcttct
    39481 atttctggat aagactgcca tagtccagga gttaccttat tgacggcctt atctgtcgtt
    39541 tgagctgata aaatcaccgc aatcaacaat tgaaaaggtg tttcccagtc taactctccc
    39601 ttagcctcag gaaacatttg accaatgatg gtcaggactt ttgctaatct tgcttttcca
    39661 attctcatga atcactccat aaattcatcg cagatagaaa atcctctgat atcatcactt
    39721 gagaaagatc ttcgccttct ctaacacgtc tacgttcttc tacttgtcga agattaacaa
    39781 taccttcttt tcgccaatta cgtaagatag cctggatata tttccaattt gttttgccgt
    39841 tgaagacagc ttcttttaaa gcttctcgta tcaaatcagg atctgtttta tcatcacgaa
    39901 gcgttttttc aagatcttct aactcaaaag gactcaagaa tcgtcctagt tcacgttcaa
    39961 attcatcaac taatcgtttg aaatgatttg gtgtttcttg tttgtcaatt tcagttgccg
    40021 tttgactgac aaacaattga tctaacttgg ctaacacagg actcgcatca aaaataattt
    40081 caatttctcc agtaagttca attgtccgca tatctaaaag cccttgacta gtcaaagatg
    40141 aaatgatttt attaatatca gcaactgatt ttccaagcgc atgagcaatt tgactgggtg
    40201 ctaagtcgtc tcgctttgtc gtattttgaa gatagaaaaa ctgccagacc aaaaaatcat
    40261 ctgagctctt aaaaagatct ttgtaatgaa aaagcaaggc acttgggata accaaattac
    40321 ccgacttata atgttctaaa aaactcataa tccctcaatc aaaaggctaa aatcgaatct
    40381 atagccttta ctactttaaa tcccctaatc agatgctgat taatgtgctt acccaggaaa
    40441 ctgcattaag actttatagt catagttcct aatagcatgg cgaccattta aaccttctaa
    40501 ttcaataagg aaggcacaac cagctacaat accaccaagt ttttcaatca tttcaatagt
    40561 tgcttttacc gtaccgccag tcgctagtaa atcatcgaca atcaaaacac gttgtccagg
    40621 cttaatagca tctgcatgca tagttaaggt atcaagacca tattcttttt cgtaatcagc
    40681 agagacaaca tctcttggca gttttcctgg tttacgaacg ggagcaaaac caattcctaa
    40741 ctcaactgca acaggacaac caatgataaa accacgcgct tcaggtccaa caaccatatc
    40801 aatatcttta tcacaagcgt actgtgctat ttcacgaata gcatagctat atgctttacc
    40861 gtcagccatt aaaggtgaga tatctcgaaa cgtaatacca gctttagggt aatctttgat
    40921 cgatgcaatg taatttgtta aatccatagt taattctttc tagtggcaaa ttgccaaata
    40981 taaaatactc ttcattatat cacgaaacat atttttcgta aaataagact tctgacatta
    41041 tgtttatctg atacttcatt cgtaactacc tcaataacta ctgtcaactg ctttacttat
    41101 tgatcgtttg atttcaccaa ataatcatac atctctttcg ggctagccaa agccatgatt
    41161 tcttgaaatt tcaccaattc ttttaagtct tggtaaatgt ggctctctga aatctctcgt
    41221 ttttgcgctt gggggttaac cgtcatcagc ccatcgtcaa tcgtcacaaa agacaactct
    41281 tcaaaaattt gaatcaactt aatcagtaaa agtttttcta tgtttaaata gtgactcaac
    41341 tctgtcaatt tatgtcgtaa atcaaattca ggaaactgat agatggtttt gtagagcttg
    41401 gcaaactgct ctctgctgcc aaatcctgtt aaataataag gatgtttcat ctgattttta
    41461 aaatagatgg cgtcaaaatc cttgtgaaca aactggttgc gccaggtttt gaaatcttca
    41521 gggatgtcat taatcagaat gactctggca tttgggtctt cttcaatagt cggaatacct
    41581 tcaggaactt tggctgtttt tgtccttaag tcaagaagtt gcactccgtc aacacgagca
    41641 tctactaaca tgaattggag actcgtgttc ccattccaat ggttgacaga taaggtaact
    41701 gctagttcta aaccagtagc ttgtcggaac tcttgcagtt gacttccttg accaaaagcc
    41761 agtacgtcaa aggaagcttt gccctgactg actttaaatt taagatggct ctggtcttgc
    41821 cctatggtac gcgcttgact aacccttatg tccttgacat aaaagaccgg cttttgatga
    41881 tccatcccat aaggggctaa tttatctaaa ctctttaaaa tatcaaggct aaggtcgtcc
    41941 aaagacagtc tttcatcaat agttaacgta tttttggcag tctgatctaa gccacgttct
    42001 atcacaaact gacaaagaaa gtctgaaaga gcttccaagt tgtcaacggg cagggtcatt
    42061 cctgctgcac cagcatgtcc cccaaaggct gtaaataact cacgcttgcc atttaaggct
    42121 tcaaaaatat taatagcttc taaacttctg gccgagcctt ttgcaaagcc attatcaatg
    42181 gtcaaaacga cgaccgtttg tccaatagtt tccatgatac gaccagcgac aatcccaaga
    42241 acaccaggat gccagccagc ttgtgccaag acttgaacag gtttttgagg atcaaccata
    42301 gccatcgctt gatcaaaaat gtcttggact aaggccttac gctcttcatt ttttttctta
    42361 atcatcaagg caatcgcttg agcttcttgg tcatcaaagc ccgtcagtag ctcaatggct
    42421 ggattagggt catctaagcg ccctaaagca tttaattgcg gagcaatctg aaagccaatg
    42481 gcgtcttcat taaaatgttc caaatcaata ggagacaagg acatcaactc ctgcaagccc
    42541 actctttcgg tgtgtttgag catggccaga ccatttttga ctaaaacacg gttttcacct
    42601 gtcaagctta ccatatcggc aatggttcca atagctacca agtctagaca gtctgttggt
    42661 aaactttcta gcaaagctgt tgccaattta aaggcaacgc cacagccagc taagtgttta
    42721 aagggataat cagcatcagg atgctcagga tgaatgatgg caaaggcttc tggcaattct
    42781 tcaggcaggc tatgatggtc agttacaatg acatcaactt cctgttcttg agcatatcta
    42841 atcgcttcat gtccggccac gccattatca accgtgataa ttagggacac agcttcctgc
    42901 tcaataaaat atttatagac gctctggttg gggccatagc catctgtaaa gcggttggga
    42961 agataaacca aaggctctgc tcccatcatg tctagggttt ctttgacaat agaagccgac
    43021 gtcatgccat cagcatcata gtcgccgtaa atgagaattc gttcgccctc ttcaatagct
    43081 tgacgaattc ttggcacagc ttttgccatg tcatgtagca agtaaggatc atgcagttga
    43141 gacaagtccg ctattaaaaa ctcatctaag gcttcttcag tccttatccc tcgatcataa
    43201 atcaactgag cggcggtctg ggttagacct tttgtctttg ctagcttaaa gaagccatca
    43261 tctggcttct tgtcttttat tttccagcta tatttggatt taatcattta taattaaata
    43321 cctttcttgc aagataatca gataatttag ggaaaagggt gtaaaattga tgggtcaccg
    43381 ctaaactaaa gggcaaattc aattctcgtt tatttttccc gataatagaa accaaacgct
    43441 tagccacttg atttggttgg agagtaaatt taccaacgct ttccaaataa tgtccagacg
    43501 ggtcagcttg gtcaaaaaac ttggtggcaa tgggacctgg attcacggtg gtcacgtaaa
    43561 cccctttatc cgctaattct aagcgaaggg cattggaaaa tccgataagg gcaaacttgg
    43621 tggctgaata aatgctcgat ttggctgacg caatcaagcc tgccatggac acaatattaa
    43681 taagatggcc ttgcccctgc tctgccattt tctgaccaat caagcaagca aagtgaatgc
    43741 tcgctagggt gttaacctga aacataccag ctatttcttg ggcagaaaac tcttcaaagc
    43801 ctttgaaagc tccatagcca gcattattaa tcaagacatc aatacggcca tagcgctggt
    43861 aaatctgggc gaccattttc tcaatggcta ctggattggt aatatccaac tcaaggcatt
    43921 ctttgttgtc aatatgctga taacagtgtt ctaggcgttc tttgttacgt cctaataaaa
    43981 tcaagctgtc ttccttgggt aactgcttaa caattgcctg agccagtcct ccagaagctc
    44041 ccgtgataac aatgattctt tgtgccatta aataatcact tcctctaaat cttgtaccat
    44101 tttaacattt tcaaatatag tggcggcatc tttttccatc tggcgacaat cacgccctaa
    44161 aaagcgagct gatacatgat tgagcaagag gcgttttgcg cctgcttcat gagcgatttg
    44221 tgctgcctgc atgttggtag aatgcccgtg atttctcgca atccgctcgt cacccttacc
    44281 ataggtggat tcatgaacca aaacatctgc atctttagcg agtttaacac tggcagacgt
    44341 tttgcgcgta tcgccgataa tggtgatgat tttgcctttt ttaggggcag aaatataatc
    44401 tttggcacaa atcaggcggc cgtcttccaa ctcaacgtct tgaccatttt taattttgcc
    44461 aaagagtggt ccgaagggaa cacccgctgc ttttaaggct tctgcgtcta gggttccttc
    44521 taagtctttt tgaactactc gataacccat gcaaaaaatg gtatgcgcca gacgctctgc
    44581 atagaccaca aacttatctg tttccattat tttacctaat gatttgtcat caaattcatg
    44641 aaaatgaatc tgataaggta cacgcgctcc agaaactttt agactagtta acacgtaagt
    44701 tttaatgcca attggtccat aaatatcaag atctgtctgt tcttcactag cttgaaaaga
    44761 ccgacttgat aaaaatcctg gtaatccaaa aatgtggtcc ccatgcaaat gagtaatgaa
    44821 aatctttctt atttttcgtg gcttaatcgt cgtttctaaa atttgtcttt gggttccttc
    44881 accacaatca aacatccaaa cttcattgat ttcgtctaag agtttcaata ctagacttga
    44941 cacattgcgc tgtttggcag gttgaccggc tccggttcct aaaaattgta attccattca
    45001 gtctattctt tctattgggt aatgtaaatc ataaattctc gttgggcaaa gtcataataa
    45061 cgttgaccag taaaagcttg actaagggta cagagttcat ctacattaaa gcctttaagc
    45121 aagacaacat cattttttag acggtaaatc ttcgtcaaga gtgcgtcatc aggcgtaatg
    45181 tcttcagatt gtccttggtc aaactgcttg gcctgcattt taagttggcc tttatcttca
    45241 taaaccatgt attgtgggaa aatttgcgtt aattcaaaga agagttcggg tttcttaggc
    45301 tctgcttttt cagaaaatac caatgcaact tcttggtcat tttggtaagc aaaaccataa
    45361 gcttttccag acaaattgag gcggacaaag ggcttttctt cctcaaaaga tggttggtca
    45421 gtaaaaagcc ccaaagcctt agaaagatta aaataataat cagtcgcagc ttgcggtgac
    45481 tgtttctggt agatttcagc aaagtaggca ttaataacac ttggtggtgg tgtgataaaa
    45541 gctagttttt gctggtctgt caaactggct aacagatggt ttaggtagtt ggtatccaga
    45601 ctagtaaatc caccataggt ttttgctaaa tcaatataat tattcataaa aatcgtcaag
    45661 tctccattgc tgttttgggg aaatgtagcc cgaaatatcc tctatttctt ggtcaaacgt
    45721 gtagtggtct aaaagagcaa ctcggttcaa atcatacagc ttgtacgcct tgtcttgatg
    45781 cactttgatt ctaaaaggaa caaactggtc tcgaatttgg tcaatgatta aacgtctcaa
    45841 gagaattttg ctatcctttg aacgggctga aatcctgata tttggaaaag cagtagctgt
    45901 gaattgttct gctatatcca ccttgttata aatagctaaa cgtggaatat taagcatgtc
    45961 tagctctttt agaaggttta aaaccacttt ttcttgctca ctatgattag ggtcgctagc
    46021 gtcaatcaca tgtaacagca aatccacata tttgctttct tctagggttg atttaaaagc
    46081 agccactaat tccgttggca agtcttgaat aaagcctacg gtgtctgtta aggttgcttg
    46141 aaattgattt tctaaataga gttgctttgt agttgcatct aaggtagcaa ataattcatt
    46201 ggcttcatag tggctgtcat ctgtcaacaa gttcataatg gttgacttgc cagcattggt
    46261 gtagccaatc aagccaattt taaaggtatc tgatcccacc cgacgatctc taattgtttg
    46321 gcgatttttc tctacctgag ttaattggcg ttcaatatca gcaatctgat gacgaatcga
    46381 acggcgattt aactctagtt ggctttcacc tggtccacgg ctcccaatac cacctgcttg
    46441 acgacttaac atgatgccct gtccaaccaa acgaggtaac atatatttca attgggcaag
    46501 gtgtacttgt aatttgccct catggcttct ggcacgcatg gcaaaaatat ctaagattaa
    46561 ctgcatacgg tcaatgactt ttacctctaa aacagcttct agattagcat tttgcctagc
    46621 agtcaaccga ttgttcacaa taactgcatc aatctcatca gcttccacaa tcgccttaat
    46681 ctcatccagt ttccctgagc cgataaaggt tttgctgtcg taacgttctc gtttttggct
    46741 gaaacttgcc ataactttga caccagctgt tttggcaaga ttagctaatt ctgtcatgga
    46801 catgtcaaaa tgttctgttg tctgaagctc aactcctaaa agaatcactc tttcttgctg
    46861 acgctttgtc tcaatcatca cctttaccaa tcctccaaat tccgtaaatt ctattataac
    46921 atatcttcaa cagattctgc taattttgcg tcatgacttc tctttctgac caagaaaatc
    46981 cctgacccta tcatgtacta cctgtgggta ataaggagcc gttatggcag tgaagctaac
    47041 agccattcga ttgcggaacc aagttagctg tcgcttggca aaacgtctcg tgttttgttt
    47101 taattgatca ctagcttctg ccaaagtcat ttcacctaca aaatagggga ataattcctt
    47161 ataacctatg ccacgactag cctgaacagt cgggtaatgc tcatataacc attttgcttc
    47221 ttccaataag ccgttttcaa gcatacgatt cacgcgctga ttgatacggt catagatgac
    47281 ttggcggtca tcattcaagc cgataataag cggctcataa gccgtctcgg cattctctaa
    47341 ttcatcagca aactgagcca attcaagggc tcggatcgcc cgtctgcgat tcacctgctc
    47401 aatggtaatg ttattgactt gcaagcgttc atacaagtcg tgatcgtcca attgctccaa
    47461 ctcatttcga taggctttta ccgcctcttg atcaacttga cctcctagat gataaccttc
    47521 gagtaaactt tgtaagtaaa gaccagttcc acctacaata attggtaatt tcccacgact
    47581 aacaatgtct gaaatagctt tttgagcatc ttggacaaaa tcgtaggccg aataagactc
    47641 cgtcacctca cgaatatcaa ttaagtgatg aaccgctgct tcttgctctt cttgagtggc
    47701 cttggctgtt ccaatatcca actgtcgata aacttgctgg ctatctcctg aaataatttc
    47761 tccattaaaa gccttggcta aactaatccc aagtgctgtt tttccaaccg ctgtcggacc
    47821 aacaatcaca actattttta tttttgtcat tttcttgtct ttctattaga aaagcgtgtc
    47881 caaaaacgcc ttttacttga aaattagctt atttttcgct accatatatt ataacataag
    47941 attaaggacc actgaggtcc ttcactagaa atggagaata atcatggtta agaaatatca
    48001 atttgttaaa ggtcttgcta ctggcgtcct agcaactgct gctactgttg ctggtgctgt
    48061 ctttgctgta aaaaaaacaa tcattgaccc tgaagaagaa aaagctgctt tcattgaaga
    48121 aaaccgcaaa aaagctgcgc gtcgtcgtgt agctcgctaa cgtgacaatg gatcaattta
    48181 aaagagacta gcacattaaa gtgccggcct cttttttagt aatctcgata actagttagt
    48241 agtaactgtc ttttgatgag ccaagatatt agctgcttta cttattttga aatagaaatc
    48301 tcaggtaagc cccataaaca taagtgacta aagctgtcgc caacaatacc tctcctagca
    48361 aaagaacctg ccaacctaaa ccttgccaac ctaaaaaaga taaggtcatt tttaaggaag
    48421 tggcactaat cacaaacgga aaggtaaaag ctgaaaaacc tgggttaaag ggacgattga
    48481 gtaagcgagg aagctgtaca accacaaaag catataacag ttgtgagctg atgagaagaa
    48541 agataaccat tcctacttgt ggtctaggaa aggttgctaa ataagacgct gaaagtaaag
    48601 acagaggggc acaaaacgtt gaaatattag gcattactgc ttgacctaaa ccaatcccat
    48661 aagtcttttt ggccataaaa ggtaaaatca cagcagttaa gagaagacaa acccaaaaaa
    48721 tcacctgtcc taataaaaac tgcctactag caggtgctgt taatgccgcc attgcaattc
    48781 caacaaaaag cacggaccag gaaggaaaaa cgttatccca tgaaaaagaa aagacaaaac
    48841 gatactggta ataagcaatc aggacaagat ttcccaaaaa gaatagccac caagtgagaa
    48901 agcctaacca acaccctcct gtcactttga gaaagagtga agacaacaac atccctgtca
    48961 taaaaaaagt tggaaaaaca gaggcaatta gaggttgtcg taactgcatt ttggtatcgt
    49021 taaggttcct aaccatgcca acaagcaaga taccatagat aaaaagagct gccagaattc
    49081 ccaaataatt aaaaatcgaa acataagtag ccaacaaatt gccaaatgac aacgttccta
    49141 atgccaatcc tgacatgacc aatggtgggt ttttaaggtg tttcataagt gtccttttct
    49201 gcctattaac agctattttt agtgacataa tcttgtttat tttatcacat ttcgagcatt
    49261 tttgacacca cccgcgaaag aaaatttaag gctcttgcca ttgttttttt acattctcgc
    49321 aaaactagga aactgcttaa aaagctaagg agtgaccact cttctctaga aaaatgaaag
    49381 agtagagaag acttggtctg atctttactt cttctttttg atttagtgag ctgcattaag
    49441 cacttgttga acagctgaat cttccaccat ttttgccata aaagctgcca gatgcggata
    49501 attctcgtaa gattttggtg ttttttgaga ccatagcgcc atggcgtaag cataagcatc
    49561 tgcaatggtt tgttgatctc gataaacatg tccactctcc ccaataagac catctaaatg
    49621 cgtcatagca atatccatcc gcttgtaaga agcttgtttg actttttcaa gcgcttgatt
    49681 gtcttgagaa atagtgtagc gatgagggtt gatcattggc ctaaaaacaa ggggaaaatc
    49741 acctgttaag aagtccatga tttcgttgaa ccgactttct gccaaaagat tatcttgggg
    49801 aatgagctga gatttcaggg tttgtttcgc tataaagggc aagataatac ctgcctgtgt
    49861 gacaatttga ccatcaccaa gccgtaaagc ttaaaccatt cccaaaggat tgatggtaag
    49921 gcagtcttca gaatccagtt ttaccttctc tatctcgtaa tacagaaact cacaattctt
    49981 ttgaaaaggt tctagacaga gttggtgttg acgtcttcgc tgttgatggc tctgcatgac
    50041 aaaatgagct tggtgtccac gttcactggt atcttgttgc aaagtctttg caatttggtc
    50101 tcatcatctg tatcacaaaa aacaaaccag tttcctgatt tgttttgaga tattaggcac
    50161 ctacaaattc tggcaaggat tctccaatag cttctaaacg ttctgcccat tcttgacgtg
    50221 ataaaccatt ttcttgcaca tagcgattac gttcatgtgc acgacattca ggtgagcatc
    50281 ctcgaacata ctttgtttcg ttttcttctg aagcaaaaat ttgtttgtta caaaacggat
    50341 ttgcacaatt gacataacgt tcacaaggtg ttccatcaaa ataatcttta ctaatgacag
    50401 ttggattaac atgattaatt ggcaccgaga tacgatcatc aaaaacatac atcgcaccat
    50461 cccaaagttc accttgaact tccggatctt ttccatatgt tgcaatacca ccgtgtaatt
    50521 gtccaacatc tttaaagcct tctcgaacca tccaacccga gaatttctca cagcgaacac
    50581 caccggtaca gtacacgaca acacgttttt ccataaactt atctttgttg tcacgtaccc
    50641 attgtggtaa ctcacggaaa ttgcgaatat caggacgaat tgctccacgg aagtgaccta
    50701 agtcatactc ataatcatta cgcgtatcta aaacaacagt atcttcatca agcaaggctt
    50761 ctttaaattg tttaggattt aaatactcac ctgttgtttc caaaggatta atatcactat
    50821 caaagttatt gtcttctaac ccaaggtgca cgatctcttt cttataacga acaaacattt
    50881 tacggaaagc ttgttgattt tcctcgtcaa tcttgaacca aagatcagca aaacgctcat
    50941 cgctgtggac ccaatccata tacttctgag ttgtttcata atctccagaa acagttccat
    51001 taatcccctc atccgcaatc aaaatacgac ctttaagccc aatagattta caaaattcta
    51061 gatgtttcgc agcgtactct tgcgcatttt caattgaaac atatttataa tagagtaaaa
    51121 ctctgatttt ttctgacatt ttttctcctt cattgttatt cagttacttc ctattatatc
    51181 taggaaaaac aagtctaggc aagccatttg tttgtctttt ttttcacaaa atagatctca
    51241 atttattttt gatgagatga gatggcaacc cattactcct ttaagcaaat cattagaagc
    51301 tttatttaga aaatgctaag ataaaacaag gaggccaaaa tgacttatga actttgttta
    51361 gaatatggga cttatccgtt gtcacgtgtt gatgcttact ggggagaaga tcaaaatccc
    51421 ccaacattca ttcaagaaga tcgactgctt tgccataaac tagaaactat gaatcacctg
    51481 ttccatgatt tatttgtaac tattgaatca caattccatt atgttggttt taacatgcct
    51541 gaaaaaagag cgcagattcg gatactatat caagaagtag ctactatatt aaaatccaaa
    51601 tataaggatt atccaattaa gattgagacg tttcttcttt aaaaatctaa tactaaaaaa
    51661 ctaactgtgc ttagacagat gacacagcta gttttttagg taaaactctt cttaaatttt
    51721 aaaacgtttc gaaaaatcac taaatgcttt aatagcactt gctaaaaatg gtttcaccat
    51781 ctcatcatta attaaccttg attacttaca atcttatgaa tctgagtcaa ataaaattca
    51841 ggctgtggca ttacagagac atttaaaacc tatactcatc gttttcaagg tcagaaagag
    51901 aatgattttg aaaaggttcg tcaactcttc tagataattt tggacaaatt ttgatcaaga
    51961 aacaaaaaga gcctatcaaa taaggctttt ttatatgatt tctatccacc ttgagggaat
    52021 cgaaccccca tctcaagaac cggaatctta cgtgatatcc attacactaa aggtggtcac
    52081 aactttgtca atacccttat agtatatcat aaaatgaaat aatatgaaat aacttttcta
    52141 accagaagac aataaaaagt tgaggaaaac ctcaactttt tagatttatt acaattcaat
    52201 atcaccgaaa agatcagcca ttgagaatcc agtttgtgtt tctgggagtt cgtagtcacg
    52261 tcttgattca cgttttggac gacgtgggcg tgattgacgt ttttcttctt tgttgtctcc
    52321 ttcagcttgc gctgggcgtt cttcaagagc tttgattgat aatgatacgc gctcatcagc
    52381 tgcattcact tcaagaactt taactgttac ttcttgtcct acagaaagta catcttttgg
    52441 attttcaaca cgtttgtgtg aaatttgtga aatatgaaca agtccatcaa tacctggtaa
    52501 tacttcaaca aaagcaccga agtcagtcaa gcgttttact ttaccttcaa caacatcacc
    52561 ttgagcaagt ttttgttcaa cgccgtccca tggtccaggt gttgttgctt taagtgaaag
    52621 tgacacacga ccagcttctt cgtcaattga aagaacttta acttcaactt cttcaccaac
    52681 tgaaacaact gatttaggtg acacgttacg ttcgtgagac aattcagtca cgtgaacaag
    52741 tccgtcaaca ccaccaaggt caatgaaagc accaaaactt gttaaacgcg ctacagtacc
    52801 tgtaacgact gcaccttctg aaatcttaga gaacacttca gcacgagctt ctttagcggc
    52861 ctcttcgata acttcacgac gtgataggat gaaacggttt tctgctgcat caacttcttt
    52921 gattttagca tcaaactctt gtccaacaaa tttttcagtg ttgcgaacaa aacgagtgtc
    52981 aatcattgaa gcagggataa atccacgaag tccttcaaat tcaactgaaa ggccaccttt
    53041 aacagcacgg gtacctttaa cagtaacaac ttcgccttca cgaccaacaa gtttgtccca
    53101 ggctttacga gcttccaaac gttttttaga tactaggaaa gtaactgtat cagtatcttt
    53161 acctactact tgacgaagaa caagtacttc aactgtgtcg ccagctttaa caaagtcgtt
    53221 aatatcagca tcgcggtcgt tagtcaattc acgaagtgtc aagacacctt caacacctgt
    53281 tccttcgata acaacgtttg cttgaccgtt atcaacagtt aaaacttccg cagtgacaac
    53341 atcaccaggg ttcacttcgc taacactgtt tagcaaatct tcaaattcat tcattctaaa
    53401 aaatcctcca acaaaagcta gccaatgcta gcttttgata acaatatatt ttctcaaggt
    53461 aacccgcaac gacaacaact cttatctttg acggtctcag ggagcacctg atacctctga
    53521 ctggggtagc tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt
    53581 ggctataccc caaaaatatt tttttacaga aaactaattt tctaattaga ttagtttccg
    53641 a
//
LOCUS       DAUGSW010000010        51657 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUGSW010000010 DAUGSW010000000
VERSION     DAUGSW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51657
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.010"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(410..1816)
                     /gene="lacG"
                     /locus_tag="VIB18_000671"
     CDS             complement(410..1816)
                     /gene="lacG"
                     /locus_tag="VIB18_000671"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEQ8765698.1"
                     /translation="MTKTLSKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDAPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYIDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(1904..3601)
                     /locus_tag="VIB18_000672"
     CDS             complement(1904..3601)
                     /locus_tag="VIB18_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8765699.1"
                     /translation="MNGLIAQIEKGKPFFEKMSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIESLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFMSTMLAAIVGFLLMAANPAKEGGFLTGFMGTKGLLTAFIAAFITVNVYKTCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIIHTTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILTEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKAQFEN"
     gene            complement(3601..3918)
                     /locus_tag="VIB18_000673"
     CDS             complement(3601..3918)
                     /locus_tag="VIB18_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8765700.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(3942..4925)
                     /gene="lacD"
                     /locus_tag="VIB18_000674"
     CDS             complement(3942..4925)
                     /gene="lacD"
                     /locus_tag="VIB18_000674"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8765701.1"
                     /translation="MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDINEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKISDNASPEFAKVKAHKVNEAMKVFSEERFGVDVLKVEVPVNMKFVEG
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(4929..5858)
                     /locus_tag="VIB18_000675"
     CDS             complement(4929..5858)
                     /locus_tag="VIB18_000675"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEQ8765702.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNDFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPLLSVDEIDGFTHQFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTRDFDALKEVLQDKLFDGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKIKEV"
     gene            complement(5904..6419)
                     /gene="lacB"
                     /locus_tag="VIB18_000676"
     CDS             complement(5904..6419)
                     /gene="lacB"
                     /locus_tag="VIB18_000676"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8765703.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNLHFFDEF
                     LEKWDRGEYHD"
     gene            complement(6454..6882)
                     /gene="lacA"
                     /locus_tag="VIB18_000677"
     CDS             complement(6454..6882)
                     /gene="lacA"
                     /locus_tag="VIB18_000677"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8765704.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKHEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKSFVEGKYDGGRHQVRVDMLNKMC"
     gene            7328..8101
                     /locus_tag="VIB18_000678"
     CDS             7328..8101
                     /locus_tag="VIB18_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8765705.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
     gene            complement(8720..9112)
                     /gene="rpsI"
                     /locus_tag="VIB18_000679"
     CDS             complement(8720..9112)
                     /gene="rpsI"
                     /locus_tag="VIB18_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEQ8765706.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(9133..9579)
                     /gene="rplM"
                     /locus_tag="VIB18_000680"
     CDS             complement(9133..9579)
                     /gene="rplM"
                     /locus_tag="VIB18_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEQ8765707.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(9797..10003)
                     /locus_tag="VIB18_000681"
     CDS             complement(9797..10003)
                     /locus_tag="VIB18_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8765708.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEVDDSR"
     gene            complement(10000..10698)
                     /locus_tag="VIB18_000682"
     CDS             complement(10000..10698)
                     /locus_tag="VIB18_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765709.1"
                     /translation="MFDSKQNLAKSQWMFIIIIAVMDLVVLVATLLAKTSFQRYLVGG
                     VAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPRYDERQKQILLKGYT
                     IGFWFMIVAVWLSIFLHRFSERLVSASFLFTLALWGRLAVQTTYCNLNGVSPFVDRRF
                     GKQGILVGMIATGMSLVTIGLAVREMMAGQLKMGSFFKAGGSGSLMVLGITLLSMGAS
                     IFYRHYLDAKEADE"
     gene            complement(10834..11694)
                     /locus_tag="VIB18_000683"
     CDS             complement(10834..11694)
                     /locus_tag="VIB18_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8765710.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHAKNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(11791..12309)
                     /locus_tag="VIB18_000684"
     CDS             complement(11791..12309)
                     /locus_tag="VIB18_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEQ8765711.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            complement(12313..13059)
                     /gene="rlmB"
                     /locus_tag="VIB18_000685"
     CDS             complement(12313..13059)
                     /gene="rlmB"
                     /locus_tag="VIB18_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEQ8765712.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRH"
     gene            complement(13106..13903)
                     /locus_tag="VIB18_000686"
     CDS             complement(13106..13903)
                     /locus_tag="VIB18_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765713.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQTNQSANQEIDSTSNPFKSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLSGLVVSLAAGLFIAIQKISRRK"
     gene            complement(14100..14513)
                     /locus_tag="VIB18_000687"
     CDS             complement(14100..14513)
                     /locus_tag="VIB18_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEQ8765714.1"
                     /translation="MTNLVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(14506..15849)
                     /locus_tag="VIB18_000688"
     CDS             complement(14506..15849)
                     /locus_tag="VIB18_000688"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEQ8765715.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYQADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKALHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            complement(15877..16107)
                     /locus_tag="VIB18_000689"
     CDS             complement(15877..16107)
                     /locus_tag="VIB18_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765716.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(16586..17167)
                     /gene="cysE"
                     /locus_tag="VIB18_000690"
     CDS             complement(16586..17167)
                     /gene="cysE"
                     /locus_tag="VIB18_000690"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEQ8765717.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTIRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(17176..17928)
                     /locus_tag="VIB18_000691"
     CDS             complement(17176..17928)
                     /locus_tag="VIB18_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEQ8765718.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDDNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(17921..20053)
                     /gene="pnp"
                     /locus_tag="VIB18_000692"
     CDS             complement(17921..20053)
                     /gene="pnp"
                     /locus_tag="VIB18_000692"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEQ8765719.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            complement(20333..21064)
                     /locus_tag="VIB18_000693"
     CDS             complement(20333..21064)
                     /locus_tag="VIB18_000693"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEQ8765720.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYVGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEEVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDDNP"
     gene            complement(21074..22453)
                     /locus_tag="VIB18_000694"
     CDS             complement(21074..22453)
                     /locus_tag="VIB18_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEQ8765721.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVIFYLVATVASVLRDASVAEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQE
                     AINNVSEEI"
     gene            complement(22480..22764)
                     /locus_tag="VIB18_000695"
     CDS             complement(22480..22764)
                     /locus_tag="VIB18_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8765722.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            complement(22757..24817)
                     /locus_tag="VIB18_000696"
     CDS             complement(22757..24817)
                     /locus_tag="VIB18_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8765723.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKASKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLAEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRGEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKSVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPY
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(25171..25440)
                     /gene="rpsO"
                     /locus_tag="VIB18_000697"
     CDS             complement(25171..25440)
                     /gene="rpsO"
                     /locus_tag="VIB18_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEQ8765724.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(25616..25816)
                     /locus_tag="VIB18_000698"
     CDS             complement(25616..25816)
                     /locus_tag="VIB18_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765725.1"
                     /translation="MTMLGYRLSAEVLGSAILPLLVGYLIRQAIAQVYSDLKTAYWLF
                     GLASSVAYGGLVKAKRAHSTTR"
     gene            25942..26211
                     /locus_tag="VIB18_000699"
     CDS             25942..26211
                     /locus_tag="VIB18_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8765726.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTYRIADLDALTQLRPLRYAAH"
     gene            26312..26926
                     /locus_tag="VIB18_000700"
     CDS             26312..26926
                     /locus_tag="VIB18_000700"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8765727.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(26960..27502)
                     /locus_tag="VIB18_000701"
     CDS             complement(26960..27502)
                     /locus_tag="VIB18_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8765728.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAKKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETRANLLSQAEALLAAI"
     gene            complement(27633..28061)
                     /locus_tag="VIB18_000702"
     CDS             complement(27633..28061)
                     /locus_tag="VIB18_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8765729.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINRLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(28171..32568)
                     /locus_tag="VIB18_000703"
     CDS             complement(28171..32568)
                     /locus_tag="VIB18_000703"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEQ8765730.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDGLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     VAQRQAGFEKAAITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGVWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            complement(32822..34678)
                     /locus_tag="VIB18_000704"
     CDS             complement(32822..34678)
                     /locus_tag="VIB18_000704"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEQ8765731.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHMTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            complement(34876..36135)
                     /gene="rseP"
                     /locus_tag="VIB18_000705"
     CDS             complement(34876..36135)
                     /gene="rseP"
                     /locus_tag="VIB18_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEQ8765732.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVNLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNTLKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(36208..37002)
                     /locus_tag="VIB18_000706"
     CDS             complement(36208..37002)
                     /locus_tag="VIB18_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEQ8765733.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(37015..37764)
                     /locus_tag="VIB18_000707"
     CDS             complement(37015..37764)
                     /locus_tag="VIB18_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEQ8765734.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLVALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            complement(37983..38348)
                     /gene="yajC"
                     /locus_tag="VIB18_000708"
     CDS             complement(37983..38348)
                     /gene="yajC"
                     /locus_tag="VIB18_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEQ8765735.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVATTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETIVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(38464..38802)
                     /locus_tag="VIB18_000709"
     CDS             complement(38464..38802)
                     /locus_tag="VIB18_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HEQ8765736.1"
                     /translation="MTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRSSCPYCRRFA
                     PKLAQVATDNQKDVYFVDSENAAELAAFRENYQLVTVPALLVSYDQHQRAVCDSSLTP
                     DDILAFLTRE"
     gene            complement(38944..42441)
                     /locus_tag="VIB18_000710"
     CDS             complement(38944..42441)
                     /locus_tag="VIB18_000710"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEQ8765737.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSDDGLQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTKVLGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHTMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAQYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEAPSKGLLA
                     AGVALLLLAISLLMKRPKD"
     gene            complement(42639..44252)
                     /locus_tag="VIB18_000711"
     CDS             complement(42639..44252)
                     /locus_tag="VIB18_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEQ8765738.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAEELDVPALKTIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMENGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFATDLAGAQ
                     VIITNTDVDTVLETKHLQPWDAFCLKLKA"
     gene            complement(44381..45514)
                     /gene="ugpC"
                     /locus_tag="VIB18_000712"
     CDS             complement(44381..45514)
                     /gene="ugpC"
                     /locus_tag="VIB18_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEQ8765739.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(45812..46660)
                     /locus_tag="VIB18_000713"
     CDS             complement(45812..46660)
                     /locus_tag="VIB18_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEQ8765740.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            47000..48322
                     /gene="ska"
                     /locus_tag="VIB18_000714"
     CDS             47000..48322
                     /gene="ska"
                     /locus_tag="VIB18_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEQ8765741.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGYEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSRPAHGGKTEQGLSPKSKPFATDKGAMPHKLEK
                     ADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKAVHNSAERVNVNYEVSFVSETGDLDFTPLLRNQYHLTTLAVGD
                     SLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYKANSKTGIEEKTNNTDLISEKYYVLKKGEKPYDPFDRSHLKLFTINYVDVNTNKLL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDDTNRIIT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPKDK"
     gene            complement(48420..48863)
                     /locus_tag="VIB18_000715"
     CDS             complement(48420..48863)
                     /locus_tag="VIB18_000715"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEQ8765742.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     RQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(48878..51097)
                     /locus_tag="VIB18_000716"
     CDS             complement(48878..51097)
                     /locus_tag="VIB18_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEQ8765743.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEEILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            complement(51349..51459)
                     /locus_tag="VIB18_000717"
                     /pseudo
     CDS             complement(51349..51459)
                     /locus_tag="VIB18_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_129544913.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        15124 a        11376 c         9561 g        15596 t
ORIGIN      
        1 ttttttcata ttttttagta aaatttttga gatatcacat aagaggtcac tttataacaa
       61 atagccctct gatataaaaa acaaaactcg ttctttacag ctattttaca atctaatcgc
      121 ttcttgttat aacatcaatc tctaatcaga aaatggttac tttacttatt taatcaggtc
      181 aggagtttga atgacagaag tcaaatatct gaaaaaggat gttaaataaa actttcaaaa
      241 cccattttca tcaactaaaa acacttataa cccgatctta caactaatgg attaccatca
      301 acagcaaata atactatgct tgaaaaatgt caacatcatc tactttttgt gactataatt
      361 cagtaaacga acatgaagtg taaaaatgta ttaaaaaagt atctcaaaat cattcaatca
      421 cttgagtttc tgctactttt ttataccagt aggcactctt cttaggataa cgctcttgag
      481 tctcaaaatc gatatagaag agaccgtaac gtttttcata gccatttgac catgaaaaga
      541 catccatcag tgaccacata aagtatcctt taacatttgc accatcagaa atagcatcag
      601 aaataacttc taagtgtttt ttcacataat cgatacgtcc atcatcatag acagtattat
      661 ctacaaactc atctttgtaa ccaagaccat tttcagtgat ataaattttc ttgtagttag
      721 gataatcagc tttaacacgc atgatttgat catataagcc ttgtgggaag ataatccaat
      781 cccagtccgt ttttggagca tcaacgggtg cttttcttcg accaacaccc ttgatttggt
      841 atttagagct gcctttttcc cctttaccat tatgaatgat ttcagtctca ccatcaaaag
      901 cttgcatcca atcactcata taatagttaa taccaaggaa gtcattcaaa tcttttgcag
      961 cgtctagtgc agcaaaatct tcctcacgaa gatcaagttc accaccattt acctcaagga
     1021 tatggttaac accttccatt gttttatctg aatacttacc tagataagtt gcatcaagaa
     1081 taaatttatt atggatgata tcttccagtt cagctgctct aacatcatca ggattgttag
     1141 cgtcaaatgg atacttggtt ggaagagcat ggacaacgcc gatttcacct gaataaccac
     1201 tatctttaaa gagtttgact gcacgagcat gagagaccat catgttatgg tgtgattgga
     1261 aaactttagc aagatcatat tggatacctg gagggaattt accaaccaag tattggccat
     1321 caccaatagg cccaatttcg ttaaatgttg tccaatagtt aacttctgag aattctttaa
     1381 aacaaaattc tgcataattt acaaaatgtt caatgttctc acgattgagg aaatcaccat
     1441 ccgagtggag agcttctggt gtatcaaaat ggtgaagtgt aacaaaaggc tcaacatgac
     1501 gcttatgaca ctctgcaaag agattgtggt agtattcaac tcctttaggg ttaacttctc
     1561 cttttcctgt tggaaaaata cgagaccagg caatagagat acggatgccg ttgacaccaa
     1621 attcttcact aagtttcaaa tcgactgggt aacgattata aaaatcactt gctggctcag
     1681 ctgtgtacca atagttgtct tctaagtatt tatcccaagc tactggtcct ttgccatctg
     1741 tatgggtagc accttcagcc tggtaagcag ctgtagcacc accaaaaata aaatctttag
     1801 ataatgtttt tgtcatctca gtttctcctt gaatatcttt caaaaataaa gttcccaaaa
     1861 caatttttgt gtttgagaac tttacgacat ttaaactgtt ttcttaattt tcaaactgtg
     1921 cttttacaaa atcaagagct ccttgaccat cacgggtcaa tttgatgtat tgagcccctt
     1981 ctgttttagc taatttaata tcaagtttat cagtttccac tttcatatct tcatagttag
     2041 aagctacttg aggtgcaagg ataacaagtt gatattgtgg taaaatctca cggtgagcac
     2101 cataacttcc tgctgctgca gtgacaggtg caccatattc tttagctgct ttattcaaag
     2161 catttgctag tagtccactt gtaccaccac cggcacaaag aacgagaaca ttagtttgat
     2221 cagtgatttc tttggtttct ttagctgctg atttttcaag aatagcatca gcttttttag
     2281 tatcaaagtt tgctgctact ttttctttga gggcatctga tgaattcgta cctgctgctt
     2341 cttcagtaag aatttgctca tcatatactt ttaagaatgg gtagtagatg atgacatcaa
     2401 ctacgattaa caaagctgcc aaaatgaatg ctagcacttg gaagtttgtc ccaaggataa
     2461 gacccaatgg agctggtgtt gtccaaggta agtttgcagt gaaactgttc attccaagtg
     2521 tgtcaatgaa gaatttgaaa atccatacgt tgacaatcgg tgccaagata aatggaataa
     2581 agaaaattgg gttcaaaaca agtggagcac caaacaaaat gggttcgtta acaccaaaga
     2641 atgttggaac aactgatgca cgtccaatgg ctttgttacg ttttgatttc gtcaaccaca
     2701 tgaacatgaa tggaacgaca agtgttgcac ctgtaccacc catggtaacg atgaacattt
     2761 gagtccctga agtcaaaatc ttgtcagcat gttcaccagc ttgaagtaat tgaaggttgg
     2821 tttcagcatt tgcgtaagta atcgctgcaa tggctggttc aacaatagat ggtccatgaa
     2881 taccaacaaa ccagaagaaa gcaaatgcac cgaagataat agtgattcca acatagccat
     2941 ctgctgcttg gaacaatggt gcaagaagtt taccaattga ttctgcaacg ttaacgccta
     3001 aagtagtatg aataatcaat tcaatcacat aaagcagtac aactgataac gtaaatggaa
     3061 tcaaatcctt aaatacttga gagatatttg gtggaacctc ttctggcata cggattgtaa
     3121 cattgttttt cacacaggtt ttatagacat ttacggtaat aaaagctgcg atgaaggctg
     3181 tcaacaaacc ttttgttccc ataaatccag ttaagaaacc accttctttt gctggattgg
     3241 ctgccataag taaaaaacct acaatagcag cgagcatggt agacatgaag ttgatttggt
     3301 ttgtgcttgg taatgatcga ttcattgagt cagttaaagc tttggctgtc gtaccagcca
     3361 caaacaaacc taaaataccc attgagtagt tgtatggcgt catcaagaga ctctcaatat
     3421 ccttactcca atggaagccc catgcatttg gaacataggc aatcaagata aagatacttg
     3481 aaaacaagat aactggcata ccagcgataa aaccatcacg aatagcgcga agatagatgt
     3541 ttcgagacat tttctcgaag aaaggtttcc ctttctcaat ctgagcaatt aatccattca
     3601 ttattttgct cctctcttat aaagttcaat catgtgtttc attaaatctt gtaataaaat
     3661 ggtcgtcatt aaatgatctt gaccgtgcat taaagtgaca ctataagcta agtcatctcc
     3721 agctgcttct ttttgtagta gacttgtctg agcattgtga gcatcattca agcagtcact
     3781 acctgcagcg attaattctt ctgctttagc ataatctcct tcttgcgctg ctttaagcgc
     3841 ttccaaaaat tttgaacggg catcaccagc ataggctacg atttcaaaac ctaaaagagt
     3901 agtttcttct ctattcattg tagtttcctc cgaaaataat gttacatttt ttcagtccaa
     3961 ggacttgcag ttttatctag tactttgttt aattcgtcaa tatttttgaa accttctgta
     4021 cgcaaccatt cacgagctgc ttgtggtcct tcttcgatat agacttttac agatcctgcc
     4081 caggtagcac gtccacataa gacaccgttg aatttagcac ctgattctgc tgcaaacacc
     4141 aaagtatctt ggaacaattt ggcagaaaca cctgcactca agtaaatata tggtaaatca
     4201 gtagaagctt cttggtcacg gaaagcttga gctgcttctt cttttgtaaa gagaacctca
     4261 ccatctgcaa agccttctac aaatttcata tttactggaa cttcgacttt caagacgtca
     4321 acaccaaagc gttcttctga gaagactttc attgcttcat taactttatg agctttaact
     4381 tttgcaaact cagggctagc attgtcagag attttctcat cataagttag aatttctaag
     4441 tagaatggaa tatcttctgc acggcattca gaaccaatac gttcaatgta agcttttttc
     4501 tgctcgttga tatcttgatc tccatcaata tcatagtaaa gaaggaattt aactgcttct
     4561 gctccagctt ctttaatacg ttttgcagac caaacatcta agcaatcagg taagcgacta
     4621 gttgttgttg catcgtatcc tgttttctca tatgctaaca acaagcctgc ttcttctgaa
     4681 cgaacacgac ttgctggcaa gccatattca ggatcaagta gaattgagga tgcaaatggt
     4741 gttagttctt cagaaactaa acttttaagc tcttcaattt gttctactgt tggctctttt
     4801 gtttgatgtt gagccatcat acgtttgaga gctccacgtt ggtcaaaagc taaggcagaa
     4861 ataacaccat ctacacttag tttttccatg cttttacgtt tgttttcagt taaagtaatt
     4921 gtcatttttt atacctcttt gattttaata gattgatata acttatcgta atttgccatg
     4981 ttaacatgcc cagttgtttt ttcttgcgca tttaacatcc ctaagacatt tgcttttgtt
     5041 aataaagctc gatcatcttc atcattcgct aaacctgaag caatacctgc cactgtagaa
     5101 tcccctgaac ctacagcgct tacaatttta attttaggaa tgtcaacgtt ataaaacgta
     5161 tccttgtgct ttgcaaatac accatcagca ccgagagaaa cgattatcca ttcaattcca
     5221 tcaaataact tatcttgtaa gacttctttt aaggcatcaa aatctcttgt catttcttta
     5281 cctagaagtt gagaaagttc ttcaagatta ggcttgataa ctgttggttt actatcacct
     5341 ttcaatactg cttctagagc atttccagaa caatccagaa ccgttttctt accattaaga
     5401 ttggcaatct tgattaactt ctgatagtaa tcatctggca taccagcagg caaactgcct
     5461 gagagcgtca ctacgtcaac atcattcagt aaatacttaa attgatgagt aaatccatca
     5521 atttcatcta cacttaacag cggtcctttt tctaaaatct ccgtttgatt accttcgtgt
     5581 aaaatggcta tacatgttct ggtatcacct gaaattttat agaagcgact taaaatcgaa
     5641 tcaggaagat gattaatgat aaaatcaccg ctttctccac ctacacaacc tgtagctttg
     5701 actgtctcac caaagtcatt tagaactcgg gaaacattca agcctttacc accgggtgtc
     5761 tttgtaacgt ctacaactcg attgacagta tcgcatttta gctcatccaa agggtaggag
     5821 acgtcaatag ctggatttaa agtaactgtt aaaatcacaa tagctccttt ttctatatat
     5881 ccttatcata attctttcaa atattagtcg tgatattcac cacggtccca tttttctaga
     5941 aattcatcaa agaagtgtag gttgttttga tcttggctag catgttgcaa gctatccatt
     6001 ttttcaatcc attttttatt ttcttcagtt ggtttgtatt ccgcggctaa gaaagcatcg
     6061 ataatatcat tcatcaataa accaccgatg atttttccac caaaaccaat aacgtttgcg
     6121 tttagctctt cttttgagta gatagcagat gtcatatctc taacgagtgc tgaacgaatt
     6181 ccaggaactt tgtttacggc atttgtaata ccaacaccag taccacagat aacaacacct
     6241 agttctgctt caccacttgc tactgcttca ccaacttttt taccaaaaat tggatagtgt
     6301 gtgcgaacat tatcatacgt accacaatca ataactttat gaccttgtga ttttaggtaa
     6361 tccacaacag cgattttttc ataagtaaca atatggtcac aacctacagc aattttcatt
     6421 tttgttctcc ttgttttaac ctatttcaat caattagcac attttattaa gcatgtcgac
     6481 acgaacttga tgacgtccac catcatattt accttcgaca aagcttttga taatgttctt
     6541 tgcaattcct ggagcactaa tttcagaacc aagcgtgatg attcgagcat tgttgtgtcc
     6601 tcttgtcatg tatgctgagc gctcatctga tacttcagct gccaccattc ctttgatttt
     6661 agtagctacc atgaaagaac caacaccata tgcatcaatg acaataccta agttatcttc
     6721 ggatgcatta acttcttttg caacggctaa agttgtatct acaaagtcac gtacttcgtt
     6781 ttcactaaca tcaacgactt cgtgtttacc ttctttaagg taatctttga taacttcttt
     6841 aagttcttga cctgctttgt cagcaccgat aataattgcc attttatttc tcctatgatt
     6901 tagaataagt gaatgtggaa aacctacgta gatagttaat taacgatttg caacatcttt
     6961 tgaaataacg ctttcattat ttctatgacc taatcataca cccaccaaac ataaaagtca
     7021 acattttttt gtttattttt tataaaaata aacaaaatat gtttattttt ttcattttta
     7081 cgttattatc ctaatgtttc ttgtgtttct ttttcatttc ataaatccct ttgacagcca
     7141 ctagtaacct atcatatatt acgaaaccct tatctctatt tattgtaaac gttttattta
     7201 aaacattttc tattttgtta atttttgttt tttccaacgt ttatgtttgt tttgtttgat
     7261 ttttttattg atattatgtt atgatacctt taatagttat accctaagac actgatagga
     7321 gataagaatg aaaaagaaag agcgtcatga aaaaattctc gatatcttaa aagttgacgg
     7381 ttttataaaa gtaaaagata ttattgatga aatgaacatc tcagatatga ccgctagacg
     7441 agatctcgat acattggcag ataaaggatt acttatcagg acccatggtg gtgctcaata
     7501 tttggattat tcttcagcaa aggacgaagg tcacgagaaa acacacactg aaaagaaggt
     7561 cttacagact accgaaaaaa aacaaattgc acaaagagct aaaaacatta ttaaagatgg
     7621 cgaaactgtc tttataggtc cagggacaac attagagcat ctagctgtcg aattgaaaaa
     7681 tagaaatatc agagttatta caaatagcct tcctgttttt ttaattttgc acccgagcac
     7741 tactattgat ttgattttaa ttggtggtga atgtcgtgaa attactggag cttttgttgg
     7801 tgctattgcc attaataacc tagaaacatt aacattttca aaagcttttg tcagcgcaaa
     7861 cgcagtttac aataattcta ttgcgacgta cagtgatctc gaaggagaag ttcaaagggt
     7921 tgcattgaat aatgctgttg agaaaatcct tctagttgat agtaccaagt ttgaaagtta
     7981 tgacttctat aatttttacc aactagatca agtggactta attgtgactg ataaaaatgt
     8041 gacaactgat atcatagaaa agtacaagaa attctcaaaa atcataatcg ctgacaagta
     8101 aaggacctac tcatattaaa aagcacttca gggtttagat atatcccctg tcaagtaaac
     8161 agggagcata tctgaaagta gtgtttgtgt tataaagaag tttcttgcta acttattttc
     8221 tggttttttt cagacttatc agtcttgtac tgttcctttt tctgatgaat aacgtggaaa
     8281 taggcagaca gctatatatt tcacctctag aatggttgcc attactgtca tcaagacatg
     8341 cttgttcttt atcgtatgga gtaaagcttt cttttagcca tcaacatacc tcttaagtag
     8401 attttggttc gttaccatgt ctacttaaga gaggtcttca aagtgcttta aaacgctgat
     8461 ataacagtat attaacgttt tgagaattgt gaagctttac gagctttttt aagacctggt
     8521 ttttggttga tattctgata tacataaaga tacttataaa atcaacctat tcctggttaa
     8581 atcaatcaaa atctattaat tatatacaaa tatcttattc ccaacggtat caaaaaaggt
     8641 atcaaaagca aaaaacgaca aaaaaagcac cttgcaagag acttgcaaaa tgcttgtaat
     8701 cgttgatgta aagctgttct taacgttttg agaattgtga agctttacga gctttcttaa
     8761 gacctggttt tttacgttca accatacgtg cgtcacgtgt aagaaggcca gcgcgtttca
     8821 atgaatcgcg gaagtctggg tctacttgaa gaagcgcacg agcgatacca tgacggatcg
     8881 cacctgattg tccaccgtaa ccaccaccaa caacgttaac gaaaacgtcg tatgaacctt
     8941 cagttgatgt aactgcaaaa ggttggttaa tgatcaaacg taggtcagca tgtgggatgt
     9001 attcttctac atcttttttg ttaacagtga ttttaccagt acctggaacc aaacgaacgc
     9061 gtgcaacagc gtttttacga cggccagtac ctgcatattg tgcttgtgcc attatttaat
     9121 gctcctttcc tcttagataa gtcctgatat gtcaagtact tctggttgtt gtgctgcgtg
     9181 agtgtgctca ccgccaacga agactttcaa tttcatacct tgtgcacgtc caagagtgtt
     9241 atgtggaagc atgcctttaa ctgatttttc aatcaagcga actgcgtttt tagagcgaag
     9301 ttcaccagca gtgattgatt tcaaaccacc tgggtacatt gagtgagtgt agtaaacttt
     9361 atcagtcgct tttttaccag ttaatttaac tttttcagcg ttgataacga taacaaaatc
     9421 acctgtatca gtgtgtggtg tgaaagttgg tttgtttttt ccgcgaagta cgctagcaac
     9481 tactgcagaa agacgtccaa gtggcacatc agttgcgtca acaacgtacc atttgcgttc
     9541 aacttggcct ggtttagcca tgaaagttgt tttgttcatg atttctccta tacgaattcg
     9601 taatatttgt ttacaaggtg atgggtgttc cgtcccatcg aaggtatttg gaaggttccg
     9661 gggcctttca aatggggtaa acaataccgc ctactatgat atcaaactta agaggctcca
     9721 gtcaagtgct ttagctgatt ttattggatt attttttctt tcgtttttga ggaatggcag
     9781 agctgctctg ctggtgttaa cgagaatcat caacctccca aaaaaggtcg tctaaggtct
     9841 tatcaagcac tcgacaaatg gcaatgcaaa gattaatcgt tgggttgtaa tcaccttttt
     9901 caacagccgc aatggtttgt ctggagacgc ctaccaaatc tgctagagct tgttgagaca
     9961 aatctttgcc tgcacgcgct gcttttaatt tgaggttctt cattcatctg cctctttagc
    10021 atccagataa tgacgataga aaatactagc tcccatacta aggagcgtta tgcccaacac
    10081 cattaaagat ccactgccgc cagccttgaa aaagcttccc attttaagtt gccctgccat
    10141 catctctctt accgccaaac ctatagtgac taaactcatt cctgttgcta tcatccccac
    10201 cagtattcct tgttttccaa agcgcctatc cacaaatggc gataccccgt tgaggttaca
    10261 atatgtcgtt tgaactgcca accttcccca aagagccaat gtaaagagga agcttgcaga
    10321 taccagtctc tctgagaagc gatgaagaaa gattgacagc caaacagcca caatcataaa
    10381 ccaaaaccca atagtgtatc ctttgagaag aatctgtttt tggcgttcgt catatctggg
    10441 cagcttctga tcgtccctta ccttagaatc tagtacttcc ttgctgtcta gtctcgtttg
    10501 gagctttttc gctgtcttta gcccccatac caacaatatg agaaagctag tcaatataac
    10561 cgctacgcct ccaactaagt aacgttgaaa actggtttta gccagcagtg tcgctactaa
    10621 cacaaccaaa tccatcactg ctattatgat tataaacatc cattgtgact tagcgagatt
    10681 ttgtttgcta tcaaacatga ttcgtttctc ctttaaatct ttacatgaca taatacaaat
    10741 tattttggat attttgtcaa atatatttta cattcttgat tgatttaagc agcaaaaaag
    10801 gattgaggat ttctcttcaa tccttataag ggattaacgg gaattctgcc caatcacaaa
    10861 aactgccagg gtgttaggac caacgtgagc tgagataact ggtcctagtg gcatcataag
    10921 aacatcgcta atattctcat gcgccagcag ctcttctcgc aacttttcgg cactaccctg
    10981 atcgcttgta taagagacaa taaccgtcga atccgcaata tctttttcca cttgagccac
    11041 catttctttg atggcttttt ggcgtccccg aatttttgca atgggcacca atttcccttc
    11101 ctcatcaatc cacaaaagag gtttgatact ggctaaactg cctagaaaag ctgaaccttt
    11161 tgacagacgc ccaccacgca tcaaatgaaa aagatcatct actaagaaat aggtgcgcag
    11221 tcgaggaatc actgcttcaa caatatcttt agtctccagt aaatttttgc cactatctct
    11281 ggcttctgct gctaaaatgg ttagatagcc ttctcctcct gcagcagcca aggtatcaac
    11341 aatttcaatc accgcatcgg gataatcttc tcgaacaaga tcgcgtgcca ttagagcact
    11401 ttgataggta cccgataaaa ccgaagaaaa agcaagataa agcagtgctt tgttgttctt
    11461 agcatgttca cgaaaaacct tctcaaactc tcccacatta atctgactgg tttgaggatg
    11521 actgccagct ttcatctttt tcaaaaggta atcactacta atacggttag gaccgaccgt
    11581 ttcataaacc tctccatcgc acaaaatcgt taatcctata aggacaatat catgatcttc
    11641 tgcccaggtt tgattcaaat cagcggttga atctgtcatt attgtaaagg tcattcttac
    11701 ttctcctcat ccagtttttt agtttgataa tcaaataatt attgttttat tttatcaaaa
    11761 aaacccgcac ttggcgagtc gtaattctca ttatcgatct aactgagaca taaaatcctt
    11821 caattgaata agctgtcctt ggtcaaaagg ccgcagttta ggcgttttga gatcaatatc
    11881 tctagacatt ttatctaaat cagctttgac agtatgaact ctttgctcta attctcttgc
    11941 agtgacacga agagctcctt gagaaaaaat cgtccattgt tcatttaaat cactcgtagc
    12001 tacttctacc atatgtatag ccgtatttaa ctctgctgcc atgcgctcaa tgtagctatc
    12061 tgctgtttcg tcttcctctg taaataccac tgagatataa tactggtcat atcgttgcct
    12121 taaccccggt acatattggg catcaaaaac acaaataata ttaatattct caaaatgggc
    12181 ataatgatta agttttgtta aaagtgtgtt acgtgcctga tcaagctgat ttgtcttaaa
    12241 caactgacgg gttgattgcc aaaaggcaat catattatac ccatctacta ataatatccg
    12301 ttttttcata atttagtgcc tatttcggaa aacttcatac atgagaatag ctgccgctac
    12361 gctagcattt aagctctgta cgtgaccatt cataggaatc gtaatcattt catcaacttg
    12421 ctttttgata ttggtagaga tgcctttgcc ttcgttacca atgactaaag caagtttacc
    12481 attagtgttc cagcaatcag acggtgttcc attcatgtct gtgccaaaaa tccagaatcc
    12541 tcttgctttc aatttatcta gagtttgact aaggttagtt actctcgcta tcggaatatg
    12601 ttcaacagca cctgtagacg tctttgaaac cactggagtc acaccaacag aacgatgttt
    12661 aggaataatc actccacata catttgtagc atcagctgtc cgtaaaatcg atcctaaatt
    12721 atgaggatct gtcagaccat ctaaaataag aatcaaagga tttgcttctt gctctgctat
    12781 ttcgaggatc tcatcaacat cagtataggc aaaagctgat actctcagaa caaaaccttg
    12841 atgcacagct ccatcagtca tttgtgacaa ggttttttta ggcgtccatg aaatagcgac
    12901 ctttttttgt gtcgctaagc ttttgatgtt atccactttc tttcctctta aatcctcttg
    12961 gatataaagc ttatttcctg tatttgcttg aaggctttct gtaacggcat gaacaccata
    13021 gacgatatcg tttgtttcaa tagtatcttt atcttccatg agtttattat accatgaatg
    13081 cttcaaaata aatgcataga ctcttttatt ttcgtctaga tattttttga atagctataa
    13141 ataaacctgc agctaaactg actactagac ctgataagac ccaagggaat cctctttttg
    13201 aagtaggttt tacttcctct ttgtccacta gcatttttgt cttgttgcta ccgttttttt
    13261 ggctattact agcagttggt gtaagtttct catttttagt agatcgcttt aaggaagttg
    13321 atcgatgatt agtagctgat ttgaaaggat ttgaagtaga atctatttct tggttagctg
    13381 attgatttgt ttgagctttt gtgtctacat cgaccgaatt cgtcgttgct ttagaagtat
    13441 ccttttgttg catattagtt ggtgtttttc tagctttgtt ttgatcaaaa tgaacagttc
    13501 ctgattgacc agttactgcc ttttcttgag tatgaacggt gacagttaca tgatagtcac
    13561 cactcttttg tccagttaaa tcaaaccaag ctgtaaaacg acgctgttgc gctgccatag
    13621 tatataccca actattaata gtattatcac tagcgtcttt aagtgttatc gttgcctgag
    13681 ttggttgtct gacaggttga tctgtggtga ctgtagcatc aatataaggt tctgttccac
    13741 gcatactggc ttcaacactg acctgactaa tagttgattc agctataaca ttatcagtgt
    13801 gctgatcttg tgcatacaca gatatggctt tgccagaagt ccccagcaaa ccaataagta
    13861 aagctagtga taataagcta actgtttttt gcatagttgt cataataaat atctcctctt
    13921 taaattagtc ttaccctctc attataaact attcgaaaat gatttcatta tttttatgtc
    13981 ttttttgtta caaatgtatc tttttttata tcattatgtc tttttgatgt cataaaaaga
    14041 cttaatggct ctctaccttt acttcagacc tatgaaaata agagtctcct aggggactct
    14101 tatgaggata tcaattgttg cttttctaca tactcaatac accatctgat caattcttct
    14161 aaccgctctt tttggcccat catatcaaga taacccataa tggcttcaaa acctgtcgac
    14221 atacgatagg taataatatc ggcattcttg gctttagtat ggctattggt attgcgacca
    14281 cgcttataga tgtcttcttc tttttcggtc aatagctgcg cttctaacat agcctgaatc
    14341 aagttggctt gtgccttagc agaaacatat ctcgttgcta aacggtgtag ctggctaggt
    14401 ttcgttttac cttgaaaaat gagatgacga cgaacatagt aggaataaac cgcatcccct
    14461 tcaaaggcta gggcaatgcc attaatcaaa ttcacatcaa ctagattagt cacgcagcca
    14521 cctcacacca tctttggtat ctagcagctt gatgccttga gctgctaact gatctcgaat
    14581 ggcatcagct gtggcaaaat cacgattcgc gcgtgcttct tgtcgcttgg caatcaaggc
    14641 ttcaatgtca acctcaagca cctcttcttc aaagataatg ccaaaaacag ctaacatttt
    14701 ctcaaaagcg cttttaacag gttctgtata ggagccagaa ttaatccact tagccatgtc
    14761 aaatacgacg gtaatcccat ttgctgtatt gaaatcatcg tccatagcgt cttggaaagc
    14821 tattacaaac tgttttagct cttgctcatc tgcagtttct gtcagcggtt gttgcaaggt
    14881 gtttttaaga tacttcagat tgatttccgc atcatgaaga gccttttcag tgaagttaat
    14941 tggttttcgg tactgttgtg tcgcaagaaa gaatcgcaaa acctgaccat caacggtttg
    15001 taacatgtca tgaacggtca caaaattacc tagtgacttg gacatttttt cgttatcaac
    15061 agtgacaaac ccattgtgca tccaatagtt agcaaaagtc ttgcctgttt tggcctcaga
    15121 ttgggcaatt tcattggtat gatgaggaaa ttccaaatca gctccgccac catgaatatc
    15181 aatggtatca ccaagaattt cagtagccat cacagaacat tcaatgtgcc agcctggacg
    15241 accaaacccc caggggctat cccaagaaac ctcacctgcc ttagctgatt tccaaagagc
    15301 aaagtccagt ggattttctt ttaaagctgt ctcagcatct gttcgaccac tggctccaac
    15361 ttcaagttct gacagggttt tattagctag cttggcataa tgctctgact tttccacgcg
    15421 gaaatacaca tctccatctg cttggtaagc aaaatctttt tcaatgaggc tttcaacaaa
    15481 tgaaatgatt tctgctatat aatccataac acgaggattt tgtgtggctg gcttaacacc
    15541 aagtgccttg gtatcttcta taaaagctgc aataaagcga tctgacaatt ctttaggaga
    15601 aacacctgct tgagtagcag ccttgataat tttatcatcg acatcggtaa aattggaaat
    15661 gtaattgacc tgatagccag tatactcaaa ataacgtcga atggtgtcaa aagcgaccgc
    15721 tgatctagca tttccaatat gaatataatt atagaccgtc ggtccacaaa cgtacatatt
    15781 gactgtattt tcagtcaaag gtacaaactt gcggagcgaa cgggtcatgg tatcataaat
    15841 tttaatcatg taaactcctt attcaatatc ctagcattag ttgtcatctt gatatcctaa
    15901 gtctttttct gaaatgctat tccacctttt caacaattta atattaataa ccaaacctat
    15961 taaccaaaat agggtcaaaa tgaagtatat aatcgcttta accatgtctt gtctcagtaa
    16021 aaagattaga ctagccacca gtgtaatact agaaacaagg atagacaaac tcataatgac
    16081 atacagccca actcttattt tattcatgag gctcctttat taacgaaaaa ccttcacaac
    16141 ctgtgaaggc ttcagaaagt agacaaaccc acttttatgc tcaaaaagca tgaatagatc
    16201 tgctgatttg acatcaggtt tcctatttct gcatgtgggg tgagccaaaa cagctgcttt
    16261 ttgttgtggt aaaagtggca tcaatactga cagtgatgcc catacggatg tttgagacct
    16321 taggctcaaa actaaggcat ggaattccaa aggaagtcgc tgccgtaagc accacctgag
    16381 aaaaagtatc acaatagact gtttcttcag tctaagactt gcttagttga tgctctttta
    16441 cgcgtttttt gtattttgta acattcccat atcactacac tcagcaacca aactgatagg
    16501 gctagctaag ttcaacattg ctctactaga aagtcccaaa atattttatt ggaagtcatc
    16561 agcgcttctt tttgttattt tccgatcatt ttgacaactg ataagagacc tctcgttgtt
    16621 tttgtaaact ttgaatttga cgattatctt tttgcccatg cactcgtact atcttagctg
    16681 gcacacctac aactgtcacg tcttcaggaa catctgataa cacaacagct gctgccccta
    16741 ctttagcatt tgctccgatg tcaataggtc caatcacttg ggcatgtgcc gaaattaagg
    16801 caccttgtcg aatcgttgga tgacgcttgc cacaatcttt tccggttcca cctagggtca
    16861 ccccatgata aagcatcaca cctttttcaa caattgctgt ctctccaata acaagaccag
    16921 caccatggtc aatgaagact ccaggagcga tttgtgctcc aggatggatt tcaatttgtg
    16981 tccaaaatcg ccaaaattgg ctatgcattc tggctagtaa tttaaaatga tgtcgccaaa
    17041 gaaaatgaga caaacgatga gcagctaggg ctttgatgcc tggataagtt aggataacct
    17101 caagactatt acgagcagct gggtctagag ctttaacaat agctatactt tctttccacc
    17161 aacccatact aactcctacg acttatctaa ttctgaccaa tcaacaagaa tttgttggtc
    17221 atcaaaagga ttgatggcga caccgaacgt ttcatcaagc tcgttttcac catttcttgg
    17281 ttgataaata tcatcaatcg tccaagtcag aatcactcct tcagctttcc tgaaaaggcc
    17341 tccaaaatcg tcttggttgt accatttcgc aaagctttga agatttgaaa aggcgggaac
    17401 atagcttttt ccttcaggcg ttgacatggt aggaaaaagg cggtcgtaat ggttatcatc
    17461 tttaggataa acaaaggcgg gaacaaggta aaccttttcc atcgtatctg ccgccacatt
    17521 gtcatcactc ataagcgtat ttaacacagt ggtgtaatgg ttcataaatt gaatcatgtc
    17581 actgcttttg aaaatggtag aattcccaaa atctcccttt ttcttaaggt taaagacaag
    17641 acctgctgca ccagatgtaa tgacttcttc tagcactgca agagctgaac gctccagcca
    17701 atactgactt tgagcactct tttgttcttc tttaaagcga gccatatctt ccttatcggt
    17761 aaaaacaggg gtaaccttga caccttcgac ttctatcacg tagggttctt tagcagccca
    17821 gacaggaaaa ttatggaaag cgttgacaag cgcaaggcta tccaaaaagt tatcaggcgc
    17881 attgataaaa gctcttaagc gaatatctaa ttcatttgat ttagtcatgt ttttcttctt
    17941 ttttctctgg ttttggtggg cgtggaatca aagctttcat tgaggcatcc acacgaccct
    18001 tctcatcaat cttaatgacc ttaacatcaa cgtcttcacc cacttcaagg acatctgaca
    18061 cgttggtcgt tctagtccaa gcaatttcag aaatgtgaac aagtgcatct gtcttgtcaa
    18121 agaggttgac aaaggcacca aatttctcaa tacggacaac cttagcatgg taaacttcgc
    18181 ctaccttagc ttcacgtact aggccagcga tgatttcttt agtgcggtta atggcagctt
    18241 ggtcacttga gtagatagag acatttcctt cgtcatcaat atcaattttg acacccgttt
    18301 cggcaataat cttatcaatg gtttcgccac ctttaccgat aaccactttg attttgtcta
    18361 cgtcaatctt gatggtgtca attttcggtg cagttggggc taactcggga cgtggttcag
    18421 cgatagttgc ttcaatcaca tcaaggattt caaagcgagc ttttttagct tgtgcaagag
    18481 cttcttctag gatttgaggc gtaatccctg caatcttaat atccatttga agggctgtaa
    18541 tcccttcacg agttcctgcc actttaaagt ccatatctcc aaagtggtct tcaagacctt
    18601 ggatatcggt caagactgta taattcgtcc cgtctgaaat gagacccatg gcaatccctg
    18661 ccacaggagc cttgattggt acaccaccag ccatcagagc aagggtacca gcacagatag
    18721 aagcctgaga agacgaaccg ttagattcta gaacttcggc aactaaacga atggcataag
    18781 gaaactcttc taagcttggc aagacttgtt caagagcgcg ttcacctaag gcaccgtgtc
    18841 caatttcacg acgaccagca gctccgtaac gacccgtttc accaactgaa tattgcggga
    18901 aattgtagtg atgcaagaag cgttttttgt actctggagc aagaccatca atgatttgag
    18961 tttctcccat tggtgccaag gtcaaaattg atagcgcctg agtttgaccg cgcgtaaaaa
    19021 gacctgatcc atggaccttt ggcaagaagt caaccacagc atcaagcgga cgaatttcgt
    19081 caatcttacg accgtcagga cgaaccttgt cctctgtaat gaggcggcgc acttcagcat
    19141 gctccatttg ttcaaggatt tctgccacgt cacgcataat ggttgctagg ttttcgtctt
    19201 ctgcgtaacg ctcttcgtac tcagccttaa ccatttcttt aacggcttct gtggctgctt
    19261 cacgcgcttt tttctcttca acttgaacag ctttttgcag ttgagcattg tacttagcca
    19321 caatatcagc ttgtaagtct gcatcaacct gtaacagttc aacctcagct ttctctttac
    19381 caacaactgc tacgatttgt tcttggaagg caattaattc ttgaatggct tggtgacctt
    19441 ttaaaagagc ctcaagcatg atgtcttctg ataattcttt ggcaccagat tcaaccatgt
    19501 tgatggcttc tttgctacca gcaacggtta attctaagag tgacgcttcc atctgttctt
    19561 tatctgggtt aatgatgaac tcaccatcaa tatagccaac ttgaacacct gcaatcggtc
    19621 cattaaatgg aatatctgag atggacaagg ccagagatga gccaaacatc gctgccattg
    19681 gagcgctagc attttcatca taagaaagga cagtgttaat cacttgtact tcgttacgaa
    19741 aaccctcggc aaacatggga cgaatcgggc ggtcaatcaa gcgagctgtc aaggtcgcat
    19801 ctgttgaagg gcgtccctca cgcttcatga aacctcctgg gaatttacca gcggcataca
    19861 ttttttcttc gtaattaact tgaaggggga agaaatcacc cgttgccatt ttcttagaca
    19921 taacagctgc ggtcaggacg gttgattctc cgtaacgaac aacggttgcc ccgttggctt
    19981 gcttagcgac ttgaccaact tcaacaacaa ggggtttccc tgcaaatgtt gttgtaaagg
    20041 tttgttttga catatattct ccttttaatt ttcagagggg taaagaggta cctgttctct
    20101 gcttagattc agttgttata cgttgttttg ctacaaaaag caacctgcca cgcttgtcac
    20161 acgctcctct ttgtatcaaa cgacgtatct gctacatttt accataaaat agcagaaatt
    20221 tcactgtcag atcgcaatct cttgaaatgt ccttgaaaaa tattaaacga aacttatact
    20281 ctttaacaaa gcaaaaaaag caggttggta tgcctgcttt cgtctcctaa tatcaaggat
    20341 tgtcatcctc taaaatttta aagccgaggc tggtactgtc tttcagaaac atttgcacgg
    20401 tttcaaggga atagtcttct aaatcttttc cttgaagagg caacttggca atcaaatcag
    20461 tggtacaagt gataatgtcc acgcctagct gatcagcttg atagatatta taagtttcac
    20521 gaggactagc ccacaacaat tcgacctctt ctttttgacg acaaatgcgt agagcttctt
    20581 ccatgattgg cattgggtca acgccggtat ctgcaatacg accagcaaaa acagacacaa
    20641 tagctggaac tccagcggtt aaatgatcaa ccacagcttg agtctgctca attgtaaaaa
    20701 tggctgtgac gtttaactta atgcctttgg ctgacaactt ttgaatgagg ggacaggttg
    20761 attctcctgt tgaagtggtg actggaattt tcacatagac attgtcacct agactggcaa
    20821 ttttctcagc ttccttttcc atgcttgcga gatcatccgc aaagacttca aaggacactg
    20881 ggtagtctgt aattttggca agcacttctt tggcaaagcc aacataagaa ctgatgcctg
    20941 cttttttcat caaacttgga ttggttgtaa agcctgtgac caaacctgtt tgtaaatcct
    21001 ttaacatggt ctctaagacc gcaccgtctg aaaagacttt aacgtttagt ttttttgtca
    21061 tcatatcctc cttttagatt tcttctgaaa cattattgat ggcttcttga gattttgaca
    21121 gaaagtttgg aagcaccaat acaatagcaa gcacagcaac caccaagtaa ataccgattt
    21181 gaccaatcga cgttcctaag cggcccagta aaatccctaa aacaccgaaa tccacatctc
    21241 caaaggtcgt gtttgaaaaa ccaagtttac caagtacagg tagaagcatg gctggcaaga
    21301 aggcgagtaa taagccatta gcgaaagcac caatcatcgc accgcgacga ccacctgttg
    21361 aatttccaaa aatccctgct gttgcaccac agaagaaatg aggcaccata cctgggataa
    21421 tcaggacacc acctgcaact cctaaaatca acatcccaag taagccacca acgaaacttg
    21481 acgcaaaacc gatgataaca gcggttggcg cataagggaa gaataccgca caatccacgg
    21541 ctggaatagc atttggaatt aatttgttag caataccttg gaaggctgga atcaagtcag
    21601 ccaaaatcat gcgaacaccg gcgtagacaa ttgccacacc aaccgcaaag gtaagaccac
    21661 tcttaatggc aaaaataaat gggttttgac ctgctgctaa ttcttctgct actgaagcat
    21721 ccctcaaaac agaagccact gttgccacca agtagaaaat caccatgata agtcctgttg
    21781 aaatggtggt gttgcgcaag aaactccatt tttcagaaat ctgaaggtcc tcggtatctt
    21841 tactgtcttt gccaaccttg ctaccaaccc aggcagaaag gtaatagccc aaactaccaa
    21901 agtgtcccat agcgatttca tctccgtcag tcactttcaa cgtatactgt tgaccaatgg
    21961 ctggcgaaat agctgaccaa gctcccaaga ggaacccacc taagataatc aaaagacttc
    22021 ctttgaaacc aacagctcca agcacggcgg acaagagaca agccataaag aagctgtgat
    22081 gtcctgttaa gaaaatgtat ttgaagcggg taaaacgagc aaaagccaaa ttgagcaata
    22141 acccaaccac caagatggac atagtttcca cacccagaat cttttgagcg acagaagtga
    22201 cggcttcgtt atttggcact acgccagtga tgctaaaacc gtgctcaatg agtttggcaa
    22261 gagggtccaa attggtcaca ataacacccg cccctgcagc aagcataagg tatcccaaaa
    22321 tcggccccaa ggttcctgtc aacaccttat gagcaggtgt tttcaaagcc accaaccctg
    22381 caaaggcaat caagcccatt aaaaatgcag gttcttttaa aatatctcga ataaatgata
    22441 ataatgcttc catagtatct tcctatctcc tttaaaggct tattccttgc cactcatttc
    22501 cttgagaacc ggaaccaaat cttcttcaat ttttttacga ttggtatagc ttttaacgat
    22561 acaaaccttg gcatcctctg gaaaaatatc tttaaattct ttaacggtaa caaacaaatc
    22621 tgcacccttt ccaacagccg cattggaatc acaggattct gcatccacat caatacccaa
    22681 actagaggcg atagcttcta ctttcatgcg aagtaacaag ctactaccaa taccgtttcc
    22741 acaaaccgtt acaattttaa tcatgtgatt cgtctccttt ttcaatcata tggctaatca
    22801 gactcattat ttcctcagta ttcttagcct caattaattg ctcaatatgt tcatcatcat
    22861 ctaaaatcaa cgacagttcc tgcaaagcct tcaaatgtga actagaatcc acagcagaca
    22921 aaacaaaaat caattgcact tgcttgtatg gatcaccttc ttgcttcaaa tcaaagctga
    22981 caggttcttt tagttgtaag agagacatgc ctaactgccg cgttcctttt tcaggcgccg
    23041 catgaggaac agccacctta ggggctaaaa caatataggc cccaagctca ttgaccgaat
    23101 caatcatacc gtcgatataa gatgtttcaa tcatctggtg ttctagtaaa ggctgagcag
    23161 ccaaacgaat cgcttcctgc caatccgaaa cagcatcagc ctgcctaata aaatctgctg
    23221 ttaacaagtc caatagtcct agacctcctt tttcaatcgt taaatggtta ccaatcaggt
    23281 aacgggataa atcactaaca agtccttctt tattagtaat cgtggtgtgt ttatgaataa
    23341 tactcaacag gtcatccaaa gcgaattgct ctgacaaggg aagatgaaag tcatcacaga
    23401 ccatcttttt caacatcatt ttctcaacag gccccatcaa agcttgcgtc acataaacag
    23461 gtttagcaca gtcaaaagct actgttgaaa aaatcaaatc aaaggaagct ggatccaaca
    23521 actttatttt gtccagctgg tgaatcctaa taaactgtag ctgtggaaaa agttccttca
    23581 aggttgcctc caacatcaga gacgaactaa tgccattagg gcaaacagat aaggctacca
    23641 gctgattgct cggcctcttc ttaggggcct gcaaccatct cccaaaatga atggtaaaat
    23701 aagcaacctc atcttcatta actgatttcc ccaattgttt ttctagagga gaaaggctgc
    23761 gcttgaccaa gtaaaagaga gattcataat cttgtttgat ttgttccttc aaaggattgg
    23821 tcaagttaat gtcgtagtaa agtcggtaat aagctggcaa aaggtgactg tataggttct
    23881 gacgaagttc tggggtatcg gtgatagaca atcccgtgtt aaccgccacc gaattgatga
    23941 tttcctccat aatatcatag ataggctgct gaaagactaa ctctaagtca ccttggatac
    24001 aaccaagtaa cctagattga accaaatatt tttcttcggt tagactgggg aagttgacca
    24061 ataactggtc caccatcgtt tcaacagctg gcgaagctaa aggaaaagta tccactgctt
    24121 caccccttac attccgtgaa aatggtcgat gagcgagaag gcagaaaaaa taaatcaaat
    24181 ccctcaattt ctccgaaata aaagttaagt ggttctccct gctcagttcc tccaacgttg
    24241 ctgccatcac ctttgtctgg tcgggcaaac caagttcatg caataagtaa ctgaacaccc
    24301 aaggtcctga tgtaacttgc aaaagagaac tgaccgctga ttctaagaga cgccgcaagg
    24361 ctaagggttc tccttcaaaa aaataaccat cctggcgatt gtaagctaaa gttacctgaa
    24421 aagcttgtac ccgatcacgc accaagttta aatcagcaat aacagaattt ctgctgagcc
    24481 gtaacaagct ttccaagtgg ttaatggaga taaattcttt agccatcatg atgtaaatga
    24541 taatcatgtc cagacgctca tcttgaaaga gatagtcgtc taaggtaggt agcatgcgat
    24601 tcaacaagtc cttttcagca aggtctggcg gataaaccag ctgcctgtcc agagcaataa
    24661 ggggtaactg atagagtgac aacgtgtcat tgattttagc aatatctgcc agtatatgac
    24721 gtttgcttgc ctttaaaatg gattcaaatg cctccagtga atgtccttta tatttagaaa
    24781 agagttgata gtttctgatg agctcatgag atagcatgtc atctcctcct ataatgtcag
    24841 tataaaatga agcgttttca ttttcaaggc aaattgagtc caattgtccg tagtcatttt
    24901 tgactgcaat tggactcaac aggtgatatc attgtaacaa gttcctcaaa aggtggccaa
    24961 aaataggcaa atctgggaat tgattccctt tttcttcatg atacaacaaa agatacctca
    25021 tcactgagat accttttgtt gttaaataaa atcatcaact gctaaaaaaa aacagtctta
    25081 gaccattcta gccaaatgtg taagttaaca aacaacatgt caaaaatgaa aaagcccact
    25141 gcataagcag aggacttttt aaacttgaaa ttaacgacga agtccaagag attggatcaa
    25201 ctcacggtaa cggttaacat ctgtacgacg taggtatgcc aacaagttac gacggtgacc
    25261 gattttcttc atcaatccac ggtaagtagc gtggtctttt ttgtgttctt tgatgtggct
    25321 gttcaagtgg ttgatttccc aagtaagaac tgcaacttga acttctactg aaccagtatc
    25381 gccttcgtga cgtgcatatt gagcgatgat ttcatttttt ttctcttttg agattgccat
    25441 aatatattct cctttttttg cttaatccga gtcttaggat tggcactcct aaaaccaaga
    25501 aaaagttggt ttgtctttcg accactctat tctagcagat tcataatatt aggtcaaccg
    25561 ttatcctatt attctgagct ctcacatcca aaccacctca ctaggcttaa aaaggttatc
    25621 tggtcgttga atgtgctctt tttgctttaa ccaaaccacc ataagcaaca gaactagcaa
    25681 ggccaaatag ccaataggct gtttttaaat cagaataaac ctgtgcgatt gcttgcctaa
    25741 taagataacc aactaaaaga ggtaagatgg ctgatcccag cacttcagct gataagcggt
    25801 agcctagcat agtcattcat ttctttccaa caaagtgttc actgataata ttaattgctc
    25861 tagtattaac aaacccaatc cctaatccat gaacacagct tattaaccga tgcgacctgc
    25921 ctttatgaca taggtcaaga gttgacacaa aatgtttgcc aacaaaacat tacctatacc
    25981 gtcaaagagc gctttgcttc ctataccctt gaagcgcaag ccaaccaaga ggttcatcta
    26041 aaccttacat tattagcaaa ccgttttgga acaagtgatc gccatcttaa gcacgtactt
    26101 aagcagccca tttttcagcg gattatcgaa cgcatctgct tcaaaaccta tcgtattgcc
    26161 gatttagacg ctctaactca attaagacct ctgaggtatg cagcccatta acttataata
    26221 gcaatcactc taaccactac ctgacttttc tttaaaaaag aaatgatttg tgatatagta
    26281 aatccagtta aaaaaaagta aaggagtaga catgtctgca caagataaat taattaaacc
    26341 tagtcatctg attaccatgg atgacattat tcgtgaaggg aatccaactt taagagctgt
    26401 cgccaaagaa gtgagcttac ccttgtgtga tgaggatatc ctattaggag aaaagatgat
    26461 gcaatttttg aagcattctc aagatcctgt aatggcggaa aaacttggtc ttagggccgg
    26521 tgttggtcta gcagctcctc agattgatgt gtcaaaacgt atcatcgctg tgctcgttcc
    26581 taatcttcct gataaagaag gaaatcctcc taaagaagcc tatagctggc aagaagtcct
    26641 gtataatcct aaaatcgttt ctcattctgt tcaagatgca gccctttctg atggcgaagg
    26701 ttgtttatct gtcgatcgtg ttgttgaagg gtatgtggtt cgccatgctc gtgttacagt
    26761 agactactat gataaagaag gacaacagca tcgcatcaaa ttaaagggat acaacgctat
    26821 tgtggttcaa catgaaattg accatatcaa tggtgttttg ttctacgatc ggatcaatgc
    26881 taaaaacccc tttgaaacca aagaagagct cttgatttta gactaacaaa aaaaggccct
    26941 ttagcctttt tttgttagtc taaatagccg ctaaaagagc ctctgcctga gatagcaagt
    27001 ttgctcttgt ctcttttgaa atctcaagcc ttcctgttcc ccaggcatca ggattcacag
    27061 ttgcttttgt aaactctcct gctactgaag ttcggataaa cggcaatagt gctttaaact
    27121 gatcaaatac ttgatcatgc ccgccatttg caactgaaga gaccgtaacc accttaccgc
    27181 caatagcaga tgggcccgtc ggatcagaca aatcaagagc acgagacaac cagtctagca
    27241 ggtttttaac agaacctgga atagagaagt tgtaaactgg tgtaaaaatc cagatagcat
    27301 ccgctgactg aacagcttga cgagcgtcaa caactggtaa aggtgcatta gcttcgatat
    27361 cttgattcaa aacaggaacg tctttccaat ttaagtaaga tactactgct tgatgttcca
    27421 gagctttttt tgcttgagcc gctaattgat ggttaaaaga cccttcacga agcgagccaa
    27481 caataaataa aatatgtttc atctctttgt cctctttttt taaagatcgt tttaaagctt
    27541 tctaaaagtg gtatttcatt gatacttctt tttgaaattt atcactatgt agtaattata
    27601 tcttctctaa gaagagctgt aaagagattt gtttataatt gtttgaactt tttgagaagt
    27661 tcaatcagac aaagttgttc tttttcagtc aaaacagcaa aggcttcttc cacccgtgcg
    27721 acgtgtttag gcaaaacagc ttcaatcaag cgagtaccct tatctgttaa ggtaaccaca
    27781 taggctcttt tatccgtttt gtctttgcac ttgctaatcc agccattacg ttccatatta
    27841 tttagtacaa cagtcatatt ccccgaagtt gctaacaaag aatcaatcaa gcgattgatt
    27901 cgcatacagc ctttagtata tagtacttca agcacactga actgcgtggc tgttaaatct
    27961 gcctttttaa aaatatcagc cccaaaagca tctagcgttc gctgagcttt acgaaacacc
    28021 accatggctt tcaaagcggt gttcttatct aaatgactca tttgatttcc tcgctttata
    28081 cggtatgtca cagtttagta tcagagagat tagaaagtga tcttgtccct cttcttttat
    28141 gactttgcat atgactacca tcatgataat ctagaaaaag tcatcaaaaa gacttaattg
    28201 attatcttct ggcatatttc ctaaaatacc catctcatcc attttctcaa cgagcgttga
    28261 cgatgccccg cctcgtttac gcaattccat tttagagagg aattcgcctt cttgacgagc
    28321 tttaacgatt tgcttggcca cgttttcacc cagaccttct aacgctataa atggagggat
    28381 aagggtatct cctttgattt ggaattctat agcatcactt ttgtaaaggt ctaatttgcc
    28441 aaacttaaag ccgcgttcta acatttcgtt gacaatctcc aaggttgtaa agaggtcatt
    28501 ttccacattg gtggcttcat tatttttacg ttttatagta atatcttcca ttcttgcttt
    28561 aacagcatct aaaccaccac tcatggtttt taattcaaaa gccttcgcac gaatagagaa
    28621 ataagcacaa taatacataa tggggtggtg caccttgaaa taagccaccc gaagggccat
    28681 caaaacataa gctgccgcat gggctttagg gaacatgtac ttgatttttc cacacgattc
    28741 aatgtaccag tcgggcacat tgttttctcg catggcatca atatagccat tacgttcttc
    28801 ctcagaaatt tttagccata atcccttacg cacacgctcc ataatggtaa aggccatttt
    28861 tggttctaag cctgcgtgca tgaggtaaac catgatgtcg tcacgacaac cgataacggt
    28921 ttttagggtt gcaatgcctt ctttaatcaa atcttgtgca ttaccaagcc aaacatcggt
    28981 tccatgagat agtccagaca actgcaaaag ctccgcaaaa gtggtcggat gcgtctcatt
    29041 aaccatgccg cgaacaaagt tggttccaaa ttctggaatg cctagcatac cagtcggtgt
    29101 cccaatttgt tccggggtaa cgcccaaaac ctctgtccca gaaaagagag ccataactcc
    29161 cggatcatca gcaggaatag taataggatc aatgcccgat aaatcctgaa gtttacgaat
    29221 catggtcgga tcatcatgcc ctaggatatc aagtttcaag acgttttcat caatatcatg
    29281 gaagttaaag tgagttgtct gccaagaagc cgttacatca tcggctggat attgcacggg
    29341 ggtaaaatca taaacatcca tgtaattagg aataacaaca atccccccag ggtgctgccc
    29401 agtcgttcgt ttcacaccag cagcacctgc tgctagacga tccacctcag catcacgata
    29461 gaacttgcca tagtcgcgtt catagccttt gacaaatcca taagctgttt tttctgctac
    29521 ggtaccaact gttccagcac gaaaggcgta ttcgtcacca aaaatatctc ggacatccaa
    29581 atgggcactg ggctggtcat caccagagaa gttcaaatca atatcgggca ccttatcccc
    29641 atcaaaccca agaaaggtct caaagggaat gtcttgccca tctttttgat aaggggtgcc
    29701 acatttcgga cagggtttat taggcaaatc atagccagat ccaactgacc catctgtgat
    29761 aaattcagaa tgttggcagg acgggcaaac gtagtgaggc ggcataggat taacctcagt
    29821 aatcccaatc atggttgcca caaaactaga ccctacagat cccctagagc caaccagata
    29881 gcctcgctca tttgaccggt taacaagcat ttgggaagcg agataaatca cagcaaaacc
    29941 gttccccaag atagaggtta actctttttc aatgcgtaaa tcaataatat ctgggagagg
    30001 attaccataa atttcaaagg ctttttgata ggttaattcg gcaaccgtct cttcggcctt
    30061 gtcaatatac ggggtgtaaa gatcgccctt aaccacttcc acttcctcaa tacggtccgc
    30121 aaaatcctga gtattttcta caaccacttg ataagcgagg tcttttccaa gaaaggcaaa
    30181 ctcatccagc atttcattgg ttgttctaaa gtgcgcttta ggtagaggag caggttgggc
    30241 cccttcccca cggccgattg ttctattaat catggcaccc tgaccgagac tacgcacaat
    30301 aatttcacgg taaatctctt cttcaggctc tagataatgc acattcccag tggcaagcac
    30361 aggtttctta gctcgtttcc ctacttcaat gaggtcacga atcacctgct caatacctgc
    30421 ttggtctttg attaattcac ggacaaccaa tggctggtaa atggctggtg gcatgatttc
    30481 gataaaatca taatacttag ctaaatcaac cgccgcatca attcctttag tcagaacggc
    30541 atcaaaaact tccccatccg aacaagctgt tcctagtaac aacccctctc tgtgagcatc
    30601 taagacggtt cttggaatac gcggcacccc ttcaaaatat ttgatattgg aaaggctgac
    30661 cagcttaaac atatttttaa ggccaacctg attttgcaca tagatagtcg catgcttaat
    30721 ccgcgctttt ttgtaagaat cctcagctac caaatctgta ttgagttgca aaagattttt
    30781 gatgccatgc ttttctctgg catcttttag aaaaataaac aaaagacgtc ctgtggcttc
    30841 cgcgtcgtaa ttggccatat gatggtggtc tagactcact tggaaacgct tggtgagcgg
    30901 tcccaaaccg tgacgcttgt actcaggata caagtttcta gcaaattcta aggtatcaat
    30961 cacaggctgt gtgattttgg gcaagtcgtg gcgttcataa ttggcgttca taaagcccac
    31021 gtcaaaactg gcgttgtggg caaccaagat actatctttg caaaagtcct gaaaagcttt
    31081 taggacagta accaatggct tggcgccctg caaatgctta tcggtaattc ctgtcaattc
    31141 ggtggtaaag gctgaaagag gatgcccagg atcaatgaat tcatcaaact gctctacaat
    31201 atttccttta aacattttgg aagccgcaat ctgaatcagg tcattattca tagcagatag
    31261 acctgtggtt tccacgtcaa agaccacata ggtagcttcg tgcaaatcca tatcaacagg
    31321 atcataagaa ataggcacct tgtcctcaac aatattggct tctaggccaa aaatagcctt
    31381 aatcccagct ttgcgagccc tatggtagcc atgaggaaaa ctttgcacat tagcatggtc
    31441 ggtaatagca accgccttgt gtccccactt ggctgccgta tcaatcaagc tttctactgt
    31501 cggtaaggcg tccatggtag acatattggt gtgggcatga agttcgaccc gcttttgccc
    31561 ttctggcatc aggtctttgc gctcatgatg gacaatttct ttgacctgct ggacattcat
    31621 ggtgagactc ttcgtaaaag gattggtctc aatattccct tgtacccgta accaaacccc
    31681 cttagcaatc atatcaaatt tacggagctc ctcatcgtct ttagcccatt tttggagagc
    31741 aaacgaggag gtatagtctg tcattttaaa gttaatgata tggcgacctg ttctagtcgt
    31801 tttacgctcc acatcaaaaa ccatcccctc aaagacaatt cggttttctt cggtctcaat
    31861 ctcaatcatt ggtgtgatgg ctgctttttc aaatcctgcc tgacgctgcg ccacgcgctc
    31921 tttataatca aacttaggag caggtgtggc ttcctcaact ggtggcatca tggcttcaag
    31981 ggatttttgg gcttccaaat tatcctgcac agcctttttc acaagagcct gacgactgga
    32041 aacaaaattc ttggtcaaat gctcagtcat ctcctgatct gacaccatat ctatggtcaa
    32101 ggtgccaaag ccaaaggctt ctaattgctt gaccagatta ggcagatgat tgtttctaaa
    32161 atgatcgtta ttcacaaaac ctggcgctgc aataatgagt ttgtcatcct cataagtcac
    32221 tttgagcttt gagaaagaag atttaaaact agcactatta cacggtgcat gctcaaaagc
    32281 ttcttggtaa taagcttgaa gcagaccatc tgaataatcc acctgagcag cttggatatc
    32341 aaaggttacc ttaatgtcag ccgcctcaaa agttcttatc aaacgatcat gcaattcacg
    32401 ataagttgca atcggtaaaa ccgctgcaaa ggcaaaatga aattcccaca agcgtgacac
    32461 cgaatgtacc tttacctcga taatatcagc agatgaaaag gcacttgaac gtctcatgtc
    32521 aagtggcatt tctatctggt ccatcaattt agcgaataaa tctgacataa ttttctcctg
    32581 attttactag gctttatttt atcacaattc aagatgattt tcgagtttta gatggaaaga
    32641 aaagcagggc tttcttctga cgttctttgg ctaatttagt ccaagtgata gctcagctga
    32701 gatcattttt ttgtcaatct tttgtcgcca agcgcttttg gtaaagcaaa agccactctg
    32761 tatcagacaa gttcacagca aaaagaggcc actctaaaca ggcagcctct tcatttcttt
    32821 tttagtgttc ttttgttaaa atttcaaggg tttcgatgag gttttctgca ttaacttcaa
    32881 tgctgtcacc tgttgccttg attttaattt ccacgatacc ttcagcggct tttttaccaa
    32941 cagtgacacg aattggcaaa ccaatcaaat cgctatcaga gaatttcgaa ccgacgcgtt
    33001 cattacggtc atctgtcaag acatcatacc ctttagccat caagtcagct tctaacttcg
    33061 ccgtcaagtc ttgggccact tgatctttga cattaactgt aatcaaatgc acgtcaaatg
    33121 gggctaattc tttagggaag ttaatacccc aagcataacg gtaatcgcct tttggtgtct
    33181 tgttcacaaa gagacgggca tgctgttcaa tgacagcaga caaaatgcgg ctaaccccga
    33241 taccataaca acccatcaca attggaactg ttctgccatt ttcatcaaga attgttgctc
    33301 ccatgctgtc tgaataacga gtgcccaact tgaagatatg accgacttcg ataccacgcg
    33361 caaactggag aacaccatga ccatccggag acatttcccc ttctttgact tcacgaatat
    33421 ctacatattc agcctggaag tcacgtcctg gattgactcc tgtcatatgg aaaccatcct
    33481 tgttagctcc tgcaacggca ttggtaaggt tttgcacttt gcggtcagcc acaatgcgac
    33541 taccttgtgc caagttgaca ggcccaagtg agccaaaacc tgcaccaaag aaagcacggg
    33601 cttcttcttc actagctggc tctaaaaaat cagcagctag atagtttttt aatttaacgg
    33661 tattgatatg gtcatttcca actagcaaag caacaacagg ttcattatct gccacaaaaa
    33721 gcaaggtttt gatggtttgt gtttcatcta ctgaaagaaa agcagccact tcatcaatcg
    33781 ttttgcaatg tggtgtctca acttctgcca aggcatcttc agcagctact tttgaggacg
    33841 gtttgtattc gttagttgcc atctcaaggt tggcagcgta gcttgattct gttgaataag
    33901 caatagtatc ttcacctgaa atcatccaag cagccaattc tgccttaatc tcttctaaga
    33961 cctcttttgg aatatcatcc attgacgcaa tagacttgtc aagaaccacc cagcgatcaa
    34021 ggtccgtacg agctggtgta atggccataa attcttggga atctttcccc cccatggcac
    34081 cgccatctcc aataatccct ttgaaatcta aaccagctct ggtaaaaata gcttcgtaag
    34141 cttgacgata atcttcgtag gtcacatcta aatcttcata gttgtgatgg aaactatagc
    34201 cgtctttcat gataaactca cgggtacgaa gcaagccatt acgcggacgt ttttcatcac
    34261 gatacttaga ctgaatttga taaaggttta agggcaattg cttgtaagat ttgaccgcat
    34321 cacgcaccaa agtcgtaaag gtttcttcgt gggtcggacc caagataaag tctgagttat
    34381 cacggttttt aagcttatag aggtcctctc cataggtctc ataacggcct gattcacgcc
    34441 agagatcagc tgtcaaaaga gctggtgcca acatttcaac agcaccgatc ttttcaaact
    34501 cttcacgcat gatggtcttg aatttctcaa tggtacgatt tgccagtggt aaataagcat
    34561 agataccagc agaaacttgg cgcacataac cagcacgcac cataagcgcg tggctgataa
    34621 cctgggcatc acttggcatt tcgcgcaagg ttgggataag cagtttactt tgtttcatag
    34681 attattccgt tttaatacat ccccttatcc tcaaaccctt ctggaaacat caagtaagag
    34741 tgaagcggga ttattcaata atttgaatgt gtattccttt cattttgagt aagacctcaa
    34801 cccttgcaaa tcttagggtt gaggtctttt tcgatcttta acatgataag gtcagcttaa
    34861 gatgacctat cttgattaga aaaagacgcg catgatatca ttccatgtca cagcaatcat
    34921 caatacgacc atgatagcaa ccccagctag ggtgatatag gcctctgttt cttgcttgat
    34981 aggcttgcga cgaatggctt caatgatatt catcaagatt tttcccccat caagtgcagg
    35041 aatcggaatc aggttaaaga tccctaaatt gatcgaaagc attgccataa gagataagac
    35101 tgactctaag ccgttttgag cagcctgatt ggacatgtca tacatggcaa caggtccacc
    35161 taatttattg agactaaagc cagtgatcaa tcctttcaaa gtattcaaaa tagtaaacgc
    35221 cccactccaa gctaattcta gaccgcctaa gagcttatcc ttaaatcctg ttttcagact
    35281 cgccttaact cctatcgtgt atgtctttgc atgcttttgt ggtttcacag ccaccgtttt
    35341 taagcgctga tgtgacttgt aggtgacctt aatggtctgt gacgggccta gatcccgtgt
    35401 tgcaaggttt acagcctcag tgagatcatt ccagctagtc accttataac cattaattgc
    35461 gacaatttgg tcattatctc gaagaccagc cttagctgct gctccatttt cttgaacacg
    35521 gacatgattg ctactaaaat ctggcatccc accttgtaaa aagaccaaga ggataaaaac
    35581 cacaatccct aaaataaaat tattcatggg acctgcaaaa ttggtgatta aacgtccgcc
    35641 aatactagca ttttgatatt gaacatcaag cggagcaatt cttatctcag taccgtcttc
    35701 ttcaacaata gtagcatcgt gagcgacctt atatgtcttg gtttcttcta aaaccaagcc
    35761 agtaatactc agctgatctt ctaagtcata gcctgtaaca tgcattggga gactcgttgg
    35821 gtctaactta ctttgagaca agttgatgcg cttaacaaaa ccttgctcat taagggttaa
    35881 acttgctgga gtacctgttt tgatctcagt tttgtcatca ccccaaccag ccattcgcac
    35941 ataaccgccc aagggtaaca tcctcaaggt ataaagagtt cctccttggt caacatgaga
    36001 aaaaatttta gggcccattc caatggcaaa ttctcttact agaatgcctg attttttagc
    36061 aaaatagaaa tgtccaaatt catggacaat cactaaaata ccaaaaataa taataaaggt
    36121 tattattcct aacatagatt tcctttcagt ctattgcttt tttgagttct gtcgcgttgt
    36181 tgcgactcca aacattacct cttaagatta aaataaacca aagagatgca tgatgggaaa
    36241 aacaaaaatc atggaatcaa agcggtctaa aataccacca tgtcccggga taagcttacc
    36301 tgaatctttg acaccaaagt gacgtttgag agcactttca accaaatcac caaattgggc
    36361 aaaaatggaa aaaagagcga ccaaaaccaa catggtcaaa aagtgatgtg gcgcataaac
    36421 agacctatca atcaccataa agataaaaga cacaaggact gcacaagcga tccctcctaa
    36481 actaccttca atggttttgt ttggagaaac tgtaggcaat agtttgcgtc tgccaaactg
    36541 acgcccaatc agatatgctc caatatcagt ggcccaaacg ataaataagg ccaaaaagac
    36601 cttgtcaatt cctgacaggc gagcattgat caaatgttga aaaccaatcc caacataaaa
    36661 actagttgca atcggaaagg ccgcatcatc aaatgaataa gctctgctat ttaaaacagt
    36721 acctgccaaa atgaaaaaaa ccattaagct gtaaaaagca acattcgcat caattggtaa
    36781 aaaagtgagg taatggtcca taggaactgc caatacaaag gcggctaaca tggcaaaaac
    36841 accttcaaaa gaaaagactt ctaatctttt cattttcagt aattctgata ccccaatcat
    36901 ggccaaaacg cctacaaata attggaatgg taggtttcct attatgagaa aaggtaggaa
    36961 aatagctact gctactcccc cccaaacaac acgttctttc ataactatct ccttttagac
    37021 cttgccaaaa cgacgttggc ggcggttata atccgcaatg gcctttagta gctctgcctt
    37081 tttaaaatca ggccacaaga ctggtgtgaa ataaaattca ctgtaagctg attgccaagg
    37141 caagaaattg ctcaaacgca gctcaccact ggtgcgaata atcaaatcgg ggtctcggta
    37201 gagatatggc agatggtctg tcatcaagta attagcaatc aaatcctccg taatatctcc
    37261 tggatttaat ttggcatcta agacatcttg agcaataaag cgaacagcac tggtaatctc
    37321 agcacgtcct ccataattga gagcaaaatt caaaattaaa cccgtattac gttttgtttt
    37381 gtcgatggct gcatttagcg ctaccaaggt atcttcaggt aaacggctag tctctccaat
    37441 catttgaatc tttacattgt tttcatgaag cacaggcaca tatttgtcaa agaaggttac
    37501 tggtaaattc atgataaaag acacctcatc ttggggtctg gaccagtttt ctgtcgaaaa
    37561 ggcatagact gtcagaactt taacccccaa ctcagatgca gtaatcgtta cttcttgtaa
    37621 agcatccatc ccagctttat gcccaaacac tctaggtttt agtctttttt tggcccaacg
    37681 tccattacca tccatgataa ttccaatatg ctttgggata ctccccaaaa ctttttttgt
    37741 tgatttcgct tttaatccaa acatgttttt tccttattga taagcatact tatctcatat
    37801 tttatcatat ttcacgcctt ttggcttgtt ttttatcaat tagatcttat cttcacaaaa
    37861 tgttcaccta tcctctgata gatgtgtcag cttttcatga acctgttagc atcagaataa
    37921 ctgtttcagt ccagggatca aaacaaaaaa gtttggcata tttcatccaa actttccccg
    37981 ccttaatggc tttcaatggc actgtcagtg tcagtgctat ctactgtctc aacagcaggc
    38041 tcattaacaa caatggtttc ttctgtttca accagtgtcg tttctgtggt agcttttgtt
    38101 acaatacgct taatagctga tagctcaaat gtcaaaaaga cgccatccac atctaacaca
    38161 atctttttag ctgttgtagc gacttcgtca acaattgcaa acatgccacc aatcgttacg
    38221 acttcgtctc ctttttcaat agcgtttaac tgattttggc gttcttgcgc ttgttttttt
    38281 tgttgacgtt gcataaacca aatcaatcca agcatcacta caaacattaa aattgttgga
    38341 aatcccataa tgtctccttt ttattctata aaagtcatgt cttactatat caaaaatcaa
    38401 gcggtatagc aagactagac gttacctgat ttcttcttta aacgagacgc taagcgcagt
    38461 gctttactca cgagtcaaaa aagctaagat gtcatctggt gtcaaacttg aatcacatac
    38521 agccctttgg tgctgatcgt aactaaccag caaagctgga actgtcacta attggtagtt
    38581 ctcacgaaag gcagcaagct cagcagcgtt ttcgctatcc acaaaataga cgtctttttg
    38641 attatctgtt gctacttgtg ccaacttggg agcaaagcgg cgacaataag gacagctcga
    38701 acgtcctaaa aagacaatca tgtctttgcc actagcaata gctgatgtga cttctgcaac
    38761 actcgacggt ataaaattcg caacgatttc ttcaaatgtc atggatgtct ccttctcttt
    38821 tggtcttatg atacactaaa gtagcaattt tctcaatcac aaggtctttt cacagctcag
    38881 agcttttata gccgtcaaaa agaatccgca aacggcaatc tttttgtctc tattaacacc
    38941 accctaatct tttgggcgct tcatcaacag gctaatagcc aataaaagca gagctactcc
    39001 agctgctaat aagccttttg agggggcttc acccgttttt gggagctttt ggtttgtttt
    39061 agctcttttt ggcctagtca ttaatgattt gtctaggtct tttgagccat ctggtgtttt
    39121 ggtttgatga ttgtctgtct gactcttttg ctgagaggga ttagccgttt ttgaggatac
    39181 tttgaggacc agggcagtta ggccatcaat agtcaagcct tctttggtaa actggactcc
    39241 cttaggctta gcaatggcag taacaccagc ttgctcagca tcagcaagca cttgggctcc
    39301 tagcaaatag cggtaggctt gaggtaaaac taccttgcgg gtcttgttgt ctgcattgac
    39361 aaagacagca tagcgatctc catttgatgc caccgtttgg taacccatga tgaggtcctc
    39421 ttgttgaata ccatcttgtc ctgcttgggt gatcaaggtc acatcccgat ctacctcagc
    39481 tttggttgct tttgtaaagg catctgttga gcgacgcaac gcaattagtc cctgtgtata
    39541 ggcttttgtt tggttgctaa tcgggtgagc tatggaatct gttgcctttg cccagtcaaa
    39601 atgattgacc gcatcagacg aatcataaga atcgtggatg aagtaagggt attgcgctac
    39661 agcatcaatc agagtcgcct tatttggcac cttgtcatca gacacctttg tcttgtagtc
    39721 gggatttaga agctgcttgg ttcgtccata ttcctgacca gaatggataa aggcagtccc
    39781 ttgagcagtt aaaatcatgg tatttcctag acgaatacgc ttgtgaatct cttcttcagc
    39841 cactttagga tccttattga tggatttggc aatgacatca tgtaaggtca ggttgtcatg
    39901 ggctgcaata tactgcacta catctcctgg ggcatctgct tcaaaattac taggctgtgc
    39961 tttgatcgtt ttgaataaac cttctagatt ttttgcgcca ccggtaataa aggccgctgt
    40021 gccttcatta ggaaaacctg atttgagggt atttctgata tcatcagaga aaacaccgac
    40081 cgtattggtt gctttcatcc aatcttgatc tgccgcaatt tcttttttcc cctcatcacc
    40141 ttggtaggta cgccagcctt cgccaatcat aatggtattt ggattaatgg ctttggctgc
    40201 cttaaaggct tgctcaatag ctgccgcatc atggtcaccc atcatgtcga aacgaaaacc
    40261 atctacctta aattcacgag tcagataagt aatcgaatcc accaagatac gacgactcat
    40321 ggtatgtgtc gttcctagac gacctccgcc aaaactctct ctagctgtgc catcagcatt
    40381 cataaaatga tagtagttgg gttccaaatc ttcaaagaga taggttctag ccgtgtggtt
    40441 ataaaccaca tcaaaaataa cacccatacc acgtttgtga atctcattga caaggttttt
    40501 aagctctgcg atacgtaaag caggatcgtt aggatttgcc gaatacatgc cagaaagggc
    40561 aaaatagtgt tgtgggtcat aaccccagtt gtaattattg tctgaagacg tgtaggctgt
    40621 tgagcggctc ttgtccagct cattggcata aaaataactc aaaaccggta gcaattgaac
    40681 gtgggtaacc cccaagtcct tgagatagtc tagctgttca acgaaagctg aaaaagtccc
    40741 aaaagggtgt gttaacttgc cttctagagc cttatctgac gtaaaatctc gcacatgtgc
    40801 ttcatagata atagcgtctt cacgcttttt aaagttgtta attttggcaa aatcaaggcc
    40861 tgttggtcct agtttgcttg gatcaataaa ggcagctttt gctgttttga tgtcatcagt
    40921 agcagtcgca tcattccagg cagcgagaga tttggcgtaa ggatccaaaa ccatgacttt
    40981 ttcctgaccg cgcgtgattt cataaaggta atagtagcct gtgtaatcac taatgccctt
    41041 gacactgtca gaagtcagat gagctctcca aacacccttg tccgacttgg tcaaatcagc
    41101 ttgaccaaga acctttgtct gatcttgttt atcgtaaacg acaaccttaa cagtatcagc
    41161 actcggagac catagcgcta aatcaacaga accatcctta gctagggtag ctccaagttc
    41221 accatcgtaa gcatagagtt tatcttttaa ttgccaggat tggcgagcga cttggctaac
    41281 ttctccaaat gtaaccgtgt agactgcacc ttgtgcctta aaatcaccct ttaatgtcat
    41341 tacagactta tccttgtcaa gtgtcaactc atcaattgca acagttttcc ctgctttgtc
    41401 agtgatcttg atgttttgtt tcaccgcatc ttcatcaagc ccatctaagg tcgtaaaaat
    41461 ggctttaatc tcatttggcg tggtttgttc agctcctttg agactaacct gatcaatata
    41521 ataaggattg ttgtaaactt ttgggtcagt gtctttgaca aaaacctgag tatgattgtc
    41581 taactcttta aatagataat cttttggttg cactttaata gcatctcctg tcttactttt
    41641 atcaaggatt aaaaatccga tttcgttagc tccttctttt aaggggacat caacataagc
    41701 tccataaggc cctttatgtg acaagtcaag tccatttggc cagtcggtcg ttggggtttt
    41761 gacatcttta aaggtccaga cagctaagtt atcgtagtgt cccgattgat tgtggtagtt
    41821 gattcgaagg taaccttttt tcaaaggtcg ataagcgtgc gcatggtaat tctcgtctat
    41881 ccaaacttca ttcatttttg gcgtgagaag cgagatgtgc tggtcctttg aaagattctc
    41941 tccagcttta ttattaatga gataagacac ttgctggcgg tgtttagctg ctagtggcac
    42001 atctagataa tagccatagt catctttttt cgcttttgtc atggtgatag caccatttgg
    42061 ccaatccttt gaaggttgat ccacatctcc ccacacccaa agtcccaagc ttcctagcga
    42121 ctcaccagct ggcaatgttt taaaatgcat acgcaaatga tgctcagcaa tactagcagg
    42181 attagctgac gagctgtcta aaactggttt agcctccttg ctagacgatt gaagaccatc
    42241 atcagattta gcattgccat ctccttgttg agcttcatcg cgggctagtc caacaatggt
    42301 tttagcagca acttgatgtg ttaagatact aggggtgcac cctaacacga cagtcccagt
    42361 tgcagcgatt acaaaaccta tcccccactt ttttaacaga tattgatagc gctttgatcc
    42421 ttggttgact ttctttttca taagacctcc atttagtata acattcaaac aagactatct
    42481 tatcacattg cgcaagcgct tgcaagacat gccgcacttc aacttagaac acagctcaaa
    42541 caatgactat caccccttaa taggatctca aaaattaaac agccaaaacg agtttccact
    42601 cgcttggctg ttgggtaaac tcaaatcaca tacaactgct aggccttcag tttgagacaa
    42661 aaggcatccc aaggttgtaa gtgcttggtc tctaataccg tgtccacatc tgtattggtg
    42721 atgatcactt gtgcacctgc taagtctgtg gcaaagactt gctcctcatc agacacatta
    42781 acaacaatca catacgtctc ttctccaagc tgacgctgat aagcaaacac tttatcagct
    42841 gttggcaaga ggtgataatc cgcttcaact agccagtctt gctccttacg caaggcaatc
    42901 aatttttggt aggtgtaaaa aatagagtct ggatcagcaa gggcatcggc cacattgatg
    42961 tcttggtagt tggggttgac cggcaaccaa gtctcttttg cttcagaaaa gccagcatgt
    43021 gtgtccttag accactgcat cggcgttcta gcattgtctc gtcctacctt gcggatgcta
    43081 tccatcacac gcgcagctga cactccattt tccatagctt ccttagcata gttaagggac
    43141 tcaatatcat taacctcggt taagtcttta aaagggtaat tggtcatacc aatctcttct
    43201 ccttggtaaa tgtaaggggt tcctcgcatc aaatgcagta aaatagctaa agccttggct
    43261 gatttttctc ggtaagtgct gtcattgccc caaatggata agacccgtgg caagtcatgg
    43321 ttattccaaa aaagcgaatt ccagccttct cccaacttta attctgtctg ccacttgctg
    43381 aaaatagttt taagagcagg aacatccagt tcttccgcat aatcccactt gggagcgtca
    43441 ggtttatgtt gaagacccac atgctcaaat tggaagacca tggataactc tttgttttca
    43501 gggcgagaat actggcgagc aatttcaggc gttgctcccc aagtctcacc gacagtcatc
    43561 acgtcatgat tgccaaaggt tgcttgattc atttctttga ggtaatcgtg taagcgcggc
    43621 ccgttacccg tgatctccaa gtcaggaacc ttcccaatca ggtcaatcac atccatacga
    43681 aaaccaccga tgcctttggc aatccagaaa ttcatcatat cgtaaatttt atgacgtaaa
    43741 gcttcattct cccagttgag atctggctga cgtttgctaa aaaggtgcaa ataatattga
    43801 cctgatgcat tatcatattc ccaagctgag ccactaaaaa tagaagtcaa atcgttaggt
    43861 tcatctcgcc aaatataaaa atcacgctca ggactattgg gattttctct agcttcaaca
    43921 aaccaagcat gctcatcaga cgtatggttg accaccaagt ccatgataat cttaatgcct
    43981 cgctcattag ctgctgctaa gagctcatcc atatctgcca tgtctccaaa aacatcagca
    44041 atcgcttcat agtcagagat gtcataacca ttgtcatcca ttggactttg gtaaacagga
    44101 gataaccaaa tggctgtaat gccaagtttt tgcaagtagt ccagttgact ggtaatgcct
    44161 tttaaatcac caataccatt gccgctggtg tctttaaagg atctcgggta aatctgataa
    44221 atcgtagctt tatgccacca gtgtttcttc attattcttc tcctattaat cattcattca
    44281 tcttttattt taacgttttt tctctttttg tgcaatcgtt tgcgcaaatg acatgataaa
    44341 aaggctggaa cccaaccttt ttatgaatat cgcttatacc ttaacgaata gcttgttcgg
    44401 tatctctgtc aaagaaatgg cccttagcca cattaaaggt caagctaact tgctcccctg
    44461 gactatggaa atcacgcgca tctacacgag aagcaaactc agtttgtcca agcttgacat
    44521 agagcatcgt ctcagagccc agtaactcag aaaccaaaac ttctgctgtg acagttgcac
    44581 ttggataagt atcatgcacg atttgtctac tagaaatgtc ttctggacga ataccaaaag
    44641 tgactttttt ccccttgtaa ccagcagctt caagcatttt tgcttgtcct tctggaatcg
    44701 caatagcaag accatcttca ctcacaatgc ggccatcttt aacttccact tcaaagaagt
    44761 tcatggcagg gcttccgata aagccggcaa cgaatttatt agctggaagg ttatacaatt
    44821 cttgtggtga acccacttgc tcaattttac caatcgttcc attaccttga gggtttttag
    44881 tggcactcat gataacgata cgatctgcca aagtcatggc ttcagtctgg tcatgggtaa
    44941 cgtaaatagt tgttgagccg atacgacggt gaattttagc aatttcagca cgcatggaga
    45001 cacgaagctt cgcatccaag tttgacaaag gctcgtccat caagaacact ttagcatcac
    45061 ggacaatagc acgccccatg gcaacacgct gacgttgacc accagacagg tcagcaggtt
    45121 tacgctctaa aaattcggtc aaaccaagaa tctgcgcagc ttccttgaca cgacggtcaa
    45181 tatcatcttt tttgtactta cgtaatttca aaccaaaggc catgttatca tacacggtca
    45241 tgtgtgggta aagggcgtag ttttgaaaga ccatggcaat atcacggtct ttaggagact
    45301 tgtcattcac cacttcgcca ccgattttta actctccttc agaaatgtcc tcaagacctg
    45361 caatcatacg aagagtggtt gatttaccac atcctgaagg tccaacaaag acgataaatt
    45421 ctttatcttt gatgtccaag tcaaaatctt caacggcata atgagtagta tttgggtatt
    45481 ttttatagat gtgatttaga tttaattcaa ccatgtataa ctcctattta gccagcaaac
    45541 gttctagctg actgcaaagc tagaaaccgc tgatatcttt tatatgatgc ttttattata
    45601 acaaaaatag cgctttcaaa acagagacaa agcgaccaaa cttctttggg caacttgcac
    45661 aatagcaggg ctagtcaagt cgtaagggac cataaaacaa gaaaaccatg taaacacagg
    45721 ccggtcacag gagccaaaac aagctgaacg atctatcatt ctccttatca gctacagtcc
    45781 aggcagcaaa aaagaaagcc ctgtggcttt cctaatattt caacaaaaag agatgagcaa
    45841 aggctaaatc atccaattgc ttcaagtgta gtcctgattg ctgagcaaat ttatcaagtt
    45901 tgtattgcaa ggagttacgg tgaatataca agcgctgcgc tgtctgcacc agattgccgt
    45961 gttctgacca tagcgcgtga accacatcgg ccatatcact ttgaggactt aggaattggt
    46021 gaaactgacg cgtcaatgcc aaaaaagtat ggtgcgacag caaagaccac agcatcagtc
    46081 ctgaaaatgt taataatttt ctgcctgatt gttgccttaa ataggccgtt aacagctgac
    46141 attcctcctc aaaacactct ctcaatgtac ccgcagctac ttgataccag gcatttccaa
    46201 caaacatggt taaggccaaa ccaaaatcac tttctagcgt tggcaggaga tcttcaagcc
    46261 agcgcaagac ctttattgag attgcttgtc ggcataaaaa tgccgtttgg gttgcactga
    46321 taggcaaaat gacctcaagc cctgcaatca tctgttggag caactcaact aagtcatctg
    46381 gtaaagcctg ctgatgattg aggtaaatga actgagaagt ctcaaacagc tgagggggat
    46441 tgccctgatg atcaagcaaa taccgctgcc aaggtgaccc tagcggctgc aagacctcac
    46501 actgacccag ccccacctca agtaataagc gctctttttc ggataaacat gatttgggaa
    46561 aatgcacata ttggtcccct tctttgacac tcacccactc tttatctcct aacggatgag
    46621 ggcctacttg catctctgga aaatagtctt ttagctccat agccattcct ttcatgacgg
    46681 tctttaaacc attataacac atgactcttt atcgcacagt tcggtttgtt gtcagcacga
    46741 ttttgtattt tctgtctttt taatcattaa agctaaataa gggttattca tttttaggaa
    46801 gaacattcaa tcaaatagct atttatcgga agattaattt atgtttatac taaaacaggt
    46861 attatttctc ttttttcatt atcatgacgt tatcattaag atatcattta aaaacaatta
    46921 ttaggttttt gtttgtatct ataaaattat tatgttattc taataatggg gattgaaact
    46981 taacttttag gaggtttcta tgaaaaatta cttatctttt gggatgtttg cactgctgtt
    47041 tgcattaaca tttggaacag tcaagcctgt ccaagctatt gctgggtatg aatggctgct
    47101 agaccgtcca tctgtcaaca acagccaatt agttgttagc gttgctggta ctgttgaggg
    47161 gacgaatcaa gaaattagcc ttaaattttt tgaaattgac ctaacatcac gacctgctca
    47221 cggaggaaag acagagcaag gcttaagtcc aaaatcaaaa ccatttgcta cagataaagg
    47281 cgcaatgcca cataaacttg aaaaagctga cttattaaag gctattcaag aacaattgat
    47341 cgctaacgtt cacagtaacg acggctactt tgaggttatt gattttgcaa gcgatgcaac
    47401 cattactgat cgaaacggca aggtctactt tgctgaccga gatgattcgg taaccttgcc
    47461 gacccaacct gtccaagaat ttttgctaag cgggcatgtg cgcgttagac cgtatcaacc
    47521 taaagccgtt cacaactcag ctgaacgcgt taacgtcaac tatgaagtga gctttgtctc
    47581 cgaaacagga gatttagact ttacaccgtt gttaagaaac caataccatt tgaccacact
    47641 ggcagttggt gactctcttt catcacaaga gttagcagca attgcccaat ttatcctatc
    47701 aaaaaaacat ccagattata tcattacaaa acgtgactcc tcaatcgtca ctcatgacaa
    47761 tgacattttc cgtacgattt taccaatgga tcaagagttt acttaccata tcaaagaccg
    47821 ggaacaagct tataaggcca attctaaaac aggtattgaa gaaaaaacga acaacactga
    47881 ccttatttct gagaaatatt acgttcttaa aaaaggggaa aagccgtatg atccctttga
    47941 tcgcagtcac ttgaaactgt tcaccatcaa ttacgttgat gtcaacacca acaaattgct
    48001 aaaaagcgag cagctcttaa cagctagcga acgtaactta gacttcagag atttatacga
    48061 tcctcgtgat aaggctaaac tactctacaa caatctcgat gcttttggta ttatggacta
    48121 taccttaact ggaaaagtcg aggataatca cgatgacacc aaccgtatca taaccgttta
    48181 tatgggcaag cgacccgaag gagagaatgc tagctatcat ttagcttatg ataaagatcg
    48241 ttataccgaa gaagaacgag aagtttacag ctacctgcgt tatacaggga cacctatacc
    48301 tgataaccct aaagacaaat aaccacgatc ttctaaaacg atgagattaa ctgacaaaaa
    48361 aagcaagcaa cacgctatca acagttgctt gcttttttct aatctcttag ttgtagagac
    48421 tagtgacatt tcgtgtctaa aataatcgta actggtccat cattgatgag actaacctgc
    48481 atatctgccc caaaaacgcc acgctcaact ggcacaaact ctgccaattg ttcattaaag
    48541 ctatcataca actgcctagc caaatctggc ttagcagcac cagtaaaggc aggacggttt
    48601 ccctttttgg tgtcagcata aagggtaaat tgcgacacag ataagatact gcccttgatg
    48661 tcttggatag actgattcat cttgccatca gcatctgaaa aaatgcgcat gttgactatt
    48721 tttcgcacag cgtaagccaa atcttctgca ttatcatctg gtcccacacc tactaacaac
    48781 aacaatcctt gattaatagc gccagcaatt ttcccatcaa tagaaacaga ggcctctttg
    48841 acccgttgca agacaagttt catgttttta tcctttctta gccattggtc cgcttcacac
    48901 tataaacatc tggaactgcc ttgatttttt cgacaacagt ggtcagatgc gtcagatttg
    48961 gaatgccaaa gctcacgtga atattagcaa acttcatgtc tttggtcggc tgagcattga
    49021 ctgtcgatat gctcttggtt gagtttgata aaatttggag cacatcattg agcaggccac
    49081 tacgattgag cccatagatg tcaatttcag cctgataatc tttactcgaa ttgtccaaat
    49141 cccactcgac ctcaatcaag cgttcttggt agccatcttg actcttaatg ttatgacagt
    49201 ccgatctgtg aatcgcaatg ccacgccctt tagtaatgta gccgtcaata ggatcaccag
    49261 gtacaggatt acaacacttg gcaatccgca tcaagaggcc tgatgctcct tggataatga
    49321 ctccattttc actgcgaacc ttgagcacat ctttgttttc gtgtttgacc tcaccgccct
    49381 taaccaattc ttctgcttct gctttagcct tggccctttc ttcttcacgg cgctcttttt
    49441 cggttaactt gttaaagaca ctgataggac taatgtcacc aaacccaacg gctgcataga
    49501 gcgattcttc gctcttcaca ctgacttttg gaaggatctc ttcaatgcgt tttttgtcaa
    49561 ggtatttatt ggcaacgtag ccctgctctt gaaaataaga caccaacaaa tcacggcctt
    49621 tattcactga caattccttg tcttgatttt taaagaactg acgaattttg ttgcgagcct
    49681 tattggtttt gaccagtttt acccagtctc gactagggcc aaaggaattg gcattggtga
    49741 tgatttcaac cacatctcct gtttttaact tggcagtgag aggaaccata cgtccattga
    49801 ctttggcacc tgttgctttt tcaccgattt gcgtatggat cgcataagca aaatcaatag
    49861 gacctgattc ttttggcaac tcctgaacgg cccctgtcgg tgtaaagaca taaatccgtt
    49921 cagaaaaaat gtcttctttg accgaatcca caaagtccac tgcatcgcca tttgaggcat
    49981 cttgcaattc taccagctct ttgatccagt tcatgccaac ggcttgctca gcttgattga
    50041 ccttaccacg cacgcctttt ttataagccc agtgagcagc aaccccatac tcagccactt
    50101 gatgcatgtc cttagttctg atttgaatct caataggtcc ttttggccca tacacagtgg
    50161 tatgaatcga ctggtagcca ttagctttag gagctgcaat ataatccttg aagcggcctg
    50221 gcatgggacg ccaaagctcg tgaatatagc caaccatagc atagacatcg ctttgcgttt
    50281 ccatgacaca acgaatggca atcagatcaa aaatctgatc gaaacgtttc tttttgtccc
    50341 gcattttccg ataaatcgaa taaatgtgtt ttggtcggcc atacacatct ccaaacaacc
    50401 cttgttgtgt cgtataggtt ttgaccttac tgacaatagc ctctaccaaa gcttcacgct
    50461 cgcgacgttt ttctttcatc atatgggaaa ttttgtaaaa ttcggtttca ttgaggtaac
    50521 gaaaagccaa atcttctagt tcccatttga tgcgactaat ccccaaacga tgcgccaagg
    50581 gggcatagat ttccatggtt tcgcgcgaaa tacgctcttg tttgtccttg cgcaaatgtt
    50641 tgagggtgcg catattatgc aggcggtcag ccaatttcac caaaatcacg cgaatatctt
    50701 tggacatagc catcagcatt ttgcgatggt tttcggcgag ttgctcctca tgagatttgt
    50761 actcaacttt acctaacttg gtgacaccat caacgatatc acgagcatct tggccaaagt
    50821 ctgcttcgat ctcatctaaa gtaatatccg tatcttctac gacatcatgt aaaaagccac
    50881 aggcaactgt cacagcatcc agatgcaaat cagccagaat ccccgccacc tgaatcggat
    50941 ggacgatata gggttcgcct gactttctca cttggtagaa atgggccgct gttgcatatg
    51001 ctaaagcctt tgccacaaaa gccacatcag ccttggtcat ataggtggcc gctaaggcaa
    51061 tgacttcttc tcctgttacg ttcattattt ttgccatttc gttcctcatc tagcatttct
    51121 tttccctatt ttaacacttt acacacaaaa gcaaaaggca gaatctgcta ggaaagcgct
    51181 tagtgtgacc ttttcttaga aaacggttag tgagctgctt ttgatatctt ttgggatctc
    51241 tcaggcgtga gcatgatacc aacggcctgc tcccgaccaa aaatagagag aaccaagggg
    51301 ctctctctat tatgtttgct tatcagtaag gtctctcaat ttagaggatt agttgttttc
    51361 tttgcgtttt gtaacggcta ggacaccagc tgttgtcatc actgctactg ctgctgctgt
    51421 aaagaatggg ttggcttgct caccagttgc tggtagacgt ctgtggttgt tggctacagg
    51481 tgtcttagcc atattgccat tgcggcgttc tggcgtttgg ttagcttctt tgtcagcagg
    51541 tttttctgga gctggagtta cctctttgct cttttctgga gctttttcgc ctggttgctc
    51601 tggcatttct ggcgttggtg tcacttctgg gctcttttct ggagcttttt cgcctgg
//
LOCUS       DAUGSW010000011        49975 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUGSW010000011 DAUGSW010000000
VERSION     DAUGSW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49975
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.011"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            9..1307
                     /gene="rocA"
                     /locus_tag="VIB18_000718"
     CDS             9..1307
                     /gene="rocA"
                     /locus_tag="VIB18_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEQ8765744.1"
                     /translation="MLTLKLFSFVSAIPLRLKNIFYLSLSMVLFQVVFWAFFPDHFIL
                     DVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSISLVKRFIVFFVMPLFGMPYS
                     VVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQSHRASKLLVFTNSSMALYY
                     LCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIHLERYVKQNSIEAIVQQKEY
                     RELVNYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQNDISIVRLTYEGILNAEKNNA
                     KDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVSIPNCIATFFLEVVDFTKLL
                     SFLLDNAIEMSLETKQPCLSIAFLDQNHKLIIVIQSSTKQGQDDSQSVFATPALKKRD
                     DWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKPD"
     gene            complement(1408..4113)
                     /locus_tag="VIB18_000719"
     CDS             complement(1408..4113)
                     /locus_tag="VIB18_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEQ8765745.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMITHFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKKYHFGQRFPKEVYQEAQEYLAGLSQ
                     SFQVIDVSGNTISEADILDTSIAFDYDLPKRSFREPYFAIKVRLRLPITLPAMSWKTL
                     ALKLGNETTPSETVSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPNHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPISADKLLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(4128..5414)
                     /locus_tag="VIB18_000720"
     CDS             complement(4128..5414)
                     /locus_tag="VIB18_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEQ8765746.1"
                     /translation="MTRPIPASVKQFMVKVESLCGDQHPDWALNFKTSFANTLEKTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANGKGHQTDHTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHSQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVMLSYLEDLYNNLFHNESVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            5546..6586
                     /locus_tag="VIB18_000721"
     CDS             5546..6586
                     /locus_tag="VIB18_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8765747.1"
                     /translation="MTELLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLSSTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDVYLDRLVKTLSETTATKRGLVVENDWLAIQLTQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            6637..8331
                     /locus_tag="VIB18_000722"
     CDS             6637..8331
                     /locus_tag="VIB18_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8765748.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDTPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFPMRGIIEGFYGTPWTREERIDCLRFIGNKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQPDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVDELVERVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            8355..9797
                     /locus_tag="VIB18_000723"
     CDS             8355..9797
                     /locus_tag="VIB18_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8765749.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRQGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDPYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEERYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(10408..11286)
                     /locus_tag="VIB18_000724"
     CDS             complement(10408..11286)
                     /locus_tag="VIB18_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8765750.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            11482..12432
                     /locus_tag="VIB18_000725"
     CDS             11482..12432
                     /locus_tag="VIB18_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8765751.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            12442..13368
                     /locus_tag="VIB18_000726"
     CDS             12442..13368
                     /locus_tag="VIB18_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8765752.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            13449..14894
                     /locus_tag="VIB18_000727"
     CDS             13449..14894
                     /locus_tag="VIB18_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8765753.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            15200..15805
                     /locus_tag="VIB18_000728"
     CDS             15200..15805
                     /locus_tag="VIB18_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEQ8765754.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     ILVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            15795..17519
                     /locus_tag="VIB18_000729"
     CDS             15795..17519
                     /locus_tag="VIB18_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8765755.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQLQNDITLRVLGQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPLTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMERRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            17519..19003
                     /locus_tag="VIB18_000730"
     CDS             17519..19003
                     /locus_tag="VIB18_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8765756.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            18933..22439
                     /locus_tag="VIB18_000731"
     CDS             18933..22439
                     /locus_tag="VIB18_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEQ8765757.1"
                     /translation="MVYRQKSSEIVTRTITKPSRAISNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLKQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFTANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWLLYGSET
                     ASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKASTPHILITSYQHY
                     LPLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            22577..23455
                     /locus_tag="VIB18_000732"
     CDS             22577..23455
                     /locus_tag="VIB18_000732"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8765758.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEIRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQNAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            23707..24462
                     /locus_tag="VIB18_000733"
     CDS             23707..24462
                     /locus_tag="VIB18_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEQ8765759.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLYYIAVKSVK"
     gene            24515..24853
                     /locus_tag="VIB18_000734"
     CDS             24515..24853
                     /locus_tag="VIB18_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8765760.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            24855..25160
                     /locus_tag="VIB18_000735"
     CDS             24855..25160
                     /locus_tag="VIB18_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8765761.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVILD"
     gene            complement(25596..26669)
                     /locus_tag="VIB18_000736"
     CDS             complement(25596..26669)
                     /locus_tag="VIB18_000736"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEQ8765762.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCYHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(26725..27477)
                     /locus_tag="VIB18_000737"
     CDS             complement(26725..27477)
                     /locus_tag="VIB18_000737"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEQ8765763.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(27718..27788)
                     /locus_tag="VIB18_000738"
     tRNA            complement(27718..27788)
                     /locus_tag="VIB18_000738"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27754..27756),aa:Thr,seq:ggt)
     gene            27955..28209
                     /locus_tag="VIB18_000739"
     CDS             27955..28209
                     /locus_tag="VIB18_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEQ8765764.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            28227..28622
                     /locus_tag="VIB18_000740"
     CDS             28227..28622
                     /locus_tag="VIB18_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEQ8765765.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            28907..29226
                     /locus_tag="VIB18_000741"
                     /pseudo
     CDS             28907..29226
                     /locus_tag="VIB18_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264372.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            29223..29786
                     /locus_tag="VIB18_000742"
     CDS             29223..29786
                     /locus_tag="VIB18_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ8765766.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     LVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTYY
                     QKINNTHLTAAETAQLIIQKMTHIKEN"
     gene            29788..32436
                     /locus_tag="VIB18_000743"
     CDS             29788..32436
                     /locus_tag="VIB18_000743"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEQ8765767.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDFIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            32590..34998
                     /gene="cas3"
                     /locus_tag="VIB18_000744"
     CDS             32590..34998
                     /gene="cas3"
                     /locus_tag="VIB18_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HEQ8765768.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWNYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQAVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVSYGEAEKKLAYLEELGVSHFLS
                     AKDYQTIKSLLKELQPFTVNVRENDPLLDATKSFLNGQVLVLTSEYYDTERGVKYDSA
                     NFYF"
     gene            35131..35859
                     /gene="cas5c"
                     /locus_tag="VIB18_000745"
     CDS             35131..35859
                     /gene="cas5c"
                     /locus_tag="VIB18_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEQ8765769.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            35859..37754
                     /gene="cas8c"
                     /locus_tag="VIB18_000746"
     CDS             35859..37754
                     /gene="cas8c"
                     /locus_tag="VIB18_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEQ8765770.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QTQYDSFHKQLNNWIDYCEEGDVKKFLTFVQQFILKPEFLTLILDSLIGPDYQHNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYHKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            37759..38607
                     /gene="cas7c"
                     /locus_tag="VIB18_000747"
     CDS             37759..38607
                     /gene="cas7c"
                     /locus_tag="VIB18_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEQ8765771.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTVFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYNQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTL
                     EILEGL"
     gene            38609..39283
                     /gene="cas4"
                     /locus_tag="VIB18_000748"
     CDS             38609..39283
                     /gene="cas4"
                     /locus_tag="VIB18_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEQ8765772.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGYLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            39280..40305
                     /gene="cas1c"
                     /locus_tag="VIB18_000749"
     CDS             39280..40305
                     /gene="cas1c"
                     /locus_tag="VIB18_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8765773.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSSALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPSLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            40316..40606
                     /gene="cas2"
                     /locus_tag="VIB18_000750"
     CDS             40316..40606
                     /gene="cas2"
                     /locus_tag="VIB18_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8765774.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   40755..41450
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=40755..40786
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaat"
     gene            41610..42320
                     /gene="ccdA2"
                     /locus_tag="VIB18_000751"
     CDS             41610..42320
                     /gene="ccdA2"
                     /locus_tag="VIB18_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEQ8765775.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            42333..42956
                     /locus_tag="VIB18_000752"
     CDS             42333..42956
                     /locus_tag="VIB18_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEQ8765776.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            42999..44105
                     /gene="msrB"
                     /locus_tag="VIB18_000753"
     CDS             42999..44105
                     /gene="msrB"
                     /locus_tag="VIB18_000753"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8765777.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            44192..44932
                     /locus_tag="VIB18_000754"
     CDS             44192..44932
                     /locus_tag="VIB18_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8765778.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQKLVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            44929..46662
                     /locus_tag="VIB18_000755"
     CDS             44929..46662
                     /locus_tag="VIB18_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8765779.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLIMKTSSDMMAEPWHKAAIDRQAMPVLTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGLTTILVLRKWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMH
                     ELMADDTQENE"
     gene            46735..47814
                     /locus_tag="VIB18_000756"
     CDS             46735..47814
                     /locus_tag="VIB18_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEQ8765780.1"
                     /translation="MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKDFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVRDYVLIYI
                     TAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            47828..48544
                     /locus_tag="VIB18_000757"
     CDS             47828..48544
                     /locus_tag="VIB18_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEQ8765781.1"
                     /translation="MVEFVADQSFWELFPGAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(48710..49183)
                     /locus_tag="VIB18_000758"
     CDS             complement(48710..49183)
                     /locus_tag="VIB18_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8765782.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            49325..>49975
                     /locus_tag="VIB18_000759"
     CDS             49325..>49975
                     /locus_tag="VIB18_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8765783.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLD"
BASE COUNT        14978 a         9311 c        10886 g        14800 t
ORIGIN      
        1 ttgaaattat gttaacgtta aagcttttta gctttgtaag tgcaattccg cttcgcctga
       61 aaaatatttt ttatttatca cttagtatgg ttttgtttca agtagttttt tgggctttct
      121 ttccagacca tttcattctt gatgttgtga tgttggcaca gtttcttttc tttgcgctta
      181 tagccctata ctatggtaaa tcaataaaag ctaagttttt aatgttttat gccttttttc
      241 cactagtgtc tattagtttg gttaagcgat ttattgtatt ttttgttatg ccattgtttg
      301 gtatgcctta ttcagttgtt aaacataata cactactgat ttacagcatt acttgcttta
      361 gtattttttt gatttatcgc tgcattcaag tttttcattt cgatttttca acctggcgcc
      421 aatattttca atcacataga gctagtaaac tattagtgtt tactaactct tcgatggctc
      481 tatactactt gtgtgtccaa gggatagatg tgatgtcgcc ttctttatca ggacttgcta
      541 caacgactgc tcgttcaatc atagtgctct tttatttcat tttgtttctt actttattaa
      601 ttcatttaga gcgttatgta aaacaaaact ctattgaggc aattgtgcaa caaaaagaat
      661 atcgtgagct ggttaattat agtcagcacc ttggattgct gtatcaagat attcaagagc
      721 ttaggcagct attaactacc gtgtccagtc gtcttaagat tggaatcgaa caaaatgata
      781 tctctattgt gagacttact tatgaaggta tcttgaatgc tgaaaagaat aatgctaaag
      841 atgacagact tgatttaact tgtttagata aattacaagt tgaagcaatc agacatattg
      901 ttttagctaa attaattgag gcaaaaaata agaagcttaa ggttgaggta tcgatcccta
      961 attgtattgc aacgtttttt ctagaagtag tagatttcac taagctattg tcatttttgt
     1021 tagataatgc tatagaaatg agtttggaga caaagcaacc ttgcttatca atagcatttc
     1081 tggatcaaaa ccataaactt atcatagtca ttcaaagcag tactaaacaa ggacaagatg
     1141 atagtcaaag cgtgtttgct acaccggctt tgaaaaaaag agatgactgg caatttgact
     1201 taaggaatgt cacgaccatt ttaaatcgtt atgactatct cacaattagc tcgcagattc
     1261 atgatggcat tttaacccag ttaatagaaa tagctaagcc tgactgatgt taaaggtatg
     1321 aataatcact caaaatcaac ttaagagtct gagacaatag tcccagactc tttttgaata
     1381 tgttaatcta ttactaatga taatagttta ttgtttcttc caagctagag ttaaaatttc
     1441 cgctttgcca agttggctgg gtgtgctttg cttgctgtct ttttctaaca aattagtgac
     1501 cttggcattg tagtttggca ggcttaggct aaagtcacaa gttttatcgt ttgagagatt
     1561 atagctgcgc gtgataaggg cattgtctgc taagcgacgt ttgaaagctg tgagggcaac
     1621 ttggtcgttt gtacccgtca aatagctata ttctgcggct aatgttccct cgtgttggtt
     1681 tgtttgtgtg gtaataacag ggacttggcc ttcttgagct cgccagtagc tggcaaattg
     1741 tgtttgctta gtgatgcttt caaaactata agaaaggctg tgtttgccaa gacactgggc
     1801 ttcaggtgtt gggaagtaac cccagtcgcc catttcgcca acagaacgta agagagtgat
     1861 ggcaatggtg ttggtatctg gtaagatctc atattcgttg aggccatagt taccaatagt
     1921 gactccattt tcaccatcaa agagactcac aaagcattct tggtgctgtg ggttacttgg
     1981 attcttccaa aaggtggcat ctggatgatt tggacgtttg acagtttcaa aaatactgtc
     2041 agctagatga tggtctgttt taaggtgcgt tgggaatagg acgcgcaagc gatgattagt
     2101 catttggtta tcaaaacgtg tggtgaattg gaggcgagga ttatttttct ccatgcggat
     2161 aagggttgtt aaggttagct cagccttttc ttgtgaacgt cttgcttggc gttctgtgat
     2221 gtcaatgaca gcctccatct cagcctgtaa gagcttatct gcggagatag gaatggcaaa
     2281 ggtttgctgg atttcaagtt cagcaacttg agcggtgttg ctaatgatgt taagcttggt
     2341 ggtcccttga tccgcataga aaggttggtc atgatttggc tggcgagaaa tatattcatt
     2401 tccaatatcg ccacaatctt caaaccgcaa caggtcttga tagattagtc cagattgttt
     2461 atcggtgatg gttagacgac catcggtttg tatcataact tttagaaacc cattttcaag
     2521 gcactgatta ctgtcatcgt agagggaaac ggtttctgaa ggagttgttt catttcctag
     2581 ctttaatgct aaggttttcc aagacatggc tgggagagtt attggtagcc gtaatctcac
     2641 ttttatggcg aaataaggtt cgcggaagga tctcttgggc aaatcgtagt caaaagcgat
     2701 gcttgtgtcc aaaatgtctg cttctgagat agtgtttcct gatacatcaa tgacttggaa
     2761 agattgggag agtcctgcca aatactcttg agcttcttgg taaacctctt taggaaagcg
     2821 ttggccaaaa tgatattttt tccaggtcag gctgagctca gcaacacttg ttttggaatg
     2881 gccgctggta ttaaataaga cgaagggttg gctatccatt ggaaaatccc tggtatcaat
     2941 ggcgtcagca atttgcttag cagcttcttt tgctaaatag tgtccgactt cataggcttt
     3001 ttcaaagtgc gttatcattt cccgatgaac gctatcaaca ctacaaccac agatagaatc
     3061 atgagggtga ttttgcatga gggttttcca agcgtaacgc agttggtcgt gagggtaggt
     3121 acttgttacc tcataagcca ttgctgctaa gggttcggtg atgttttcga gttggcgaga
     3181 gactctggta ttagcctgtt tgaggtaaat acgagcagaa gccgtgttag ctagggtata
     3241 ccagccatcg gtttcttgac tggtaatctc tccttggacg gttgaaaggt tctctggtaa
     3301 atcatctgcg agatcagcca agtaatcttc aaagcaggaa tgcacaaatt cgtagtcagg
     3361 atagagttgg ttggctaagg cgattgcctt ggtgacatca agttgtacgg gttgatgatc
     3421 acacccgttc atcatcagaa ggtgcttggt tgaggcgaag cgttcggcgt cagcaagttt
     3481 tttatcccaa aaaagacgcg cctcagcttc tgttgtcggg atctcattgc cattgctgta
     3541 ccagttggcg aagaggagtc caagaatacg actgttatct gggccttgcc aactgatttc
     3601 agagaattgg gagctgtatt tttcactggt atccacctga ttgttaaatc cagttggacg
     3661 aatgccacga ccaaaggcag cagcttgtag gccggctttt aacatcagct gtggtgtttg
     3721 tcccatattt ccaaaggtat caggaaaata accaagtggc acactagcac cccatctgtc
     3781 acaatcttcc ttaccaatca gcatattgcg cacattggat tcactgctgg tcaaaaaatc
     3841 gtcctgtaag atatagaaag gtccgatacg gagttttccc gaagcaatgg cttgtctaat
     3901 ctcaggttct cgttcggggc gtacttttaa ataatcatct aggataatgg tttgcccatc
     3961 caaatgaaaa ctatgaaaat caggatccgt ttgaaaaact tctaacaggt catctattaa
     4021 gttaatcaga cgcatgtggt gttgttcgta agccatgtac cactcgcgat cccagtgact
     4081 gtgtgaaata atatgtactt ttttagttgc catagtggcc tcactttcta aggagcaata
     4141 ctaaagccca gatagtcaag aagtagttca cagaacatca tgttagccca agagaaccac
     4201 tcacgagtgt attgataagg atcattgaca tcgaaaccct cgtgcattaa gtgggtacca
     4261 gcatctgttg ccacaagcaa atcaagcatc tcttttttac tgtcttggtc aagagcggtc
     4321 aatccttgta aggcaagggc gatatgccag atataatttt ctggtgtatg ggaagaaccg
     4381 atgcctgctg ctgcatttcc ctgataataa taagggtttt cttggctgag aatggtgcgg
     4441 cgcgttgcca gatagatagg gtcatcttta gcgcaaaaac caaggtaagg tgcagcaagg
     4501 aggcttggaa tattagcatc atccatgatg gaaaactgtc ccagaccatc cacttcataa
     4561 gcgtaaatgg tttctccctt gctgttttga acaagggcat ggtctgcaat acccgattga
     4621 atagcttctt tcagctgctt ggcacgagta gctactgatt cattgtgaaa aaggttgtta
     4681 tataaatctt ctagatagga aagcataacc accgcaaaca tatttgaagg aatgaggtaa
     4741 ccatattgac aagcatcatc acttggtcta aagcctgacc aggtcatccc tgttggtgcg
     4801 acaggacttc cttttccagc atgtgttagg gtatcttctt tgcgccaagt atcgcgttca
     4861 aacaagtaag gagactggga gtgatcttgc tcaactgtcc ataggtcaag aatgagttct
     4921 accccacgat gaaaatcgtc attaaactga tcggtgcttc ctgtttcacg atagagcaag
     4981 taagccagtt gaatagggta gcagagggaa tcaatctcat atttgcgttc ccaaatccaa
     5041 gggttcattt gggtgtgatc tgtttggtgt ccttttccgt tagcttcttc attgaaggca
     5101 ttggcatagg gatcgataca aatgtagcgg aattggcgtt tgaccagacc ggcaataatc
     5161 tttctaattt cctcgtcttc cttggctagg aagaggtaag gtttcatttg cgcagtggaa
     5221 tcacgtaacc acatggcagg aatatctcct gtcaagagaa agctagtgcc gtcttcatag
     5281 gtctttaggg ttttttctag ggtattggca aagctggttt tgaaattaag agcccaatca
     5341 gggtgttggt ctccacaaag actttccacc ttgaccataa attgctttac actagctgga
     5401 attggtcttg tcatgtcata tcctccaaat gatatatcat ttatcttcgg tttcattata
     5461 aaggataagt tgaactttgt ctataagttt ttgaaaaggt ttacaactct tttttgacat
     5521 gctatactga tagcgggagt aaatcatgac agaattatta tacaaaaaga tatatcattt
     5581 tattaaagag cagatagcat caggtcgttt gcaaattggt gaccgcctac ctactgaaaa
     5641 agaattgtca gaacagttct cggttagccg tatcacttct aagcgagcgc ttgtagaact
     5701 ggagcaagaa ggcttgatta cgagaagtcg tgggaaagga agcttcgtag ctaaaaagca
     5761 agtgacgtcc cctgaagcga ataaggattt attgttgatt cttccttttg cttctgatta
     5821 tgaattggga gattatgcta agggaattat gacctccatt gctgaaacag ggtatcggtt
     5881 gatggtgcaa ctgtctagta cggtaaggtt agacaccctg tccgattatg ctggtattat
     5941 ttattaccca gaagatgtca atcacagtat tgatttcctg ttttactgcg accatcatca
     6001 cattccgcta gtcttgttgg ataaatctct ggaccttttt cagtttccgt ctgttgtagc
     6061 ggataataaa ggcggtgcct gtcaattgac tcagcacttg attgagcaag gctgtgacca
     6121 gattagtttt gtggcaacag gctcttttgg agaagtatca tccgttagag accgttattt
     6181 gggttactta gcggcaatgg cagaatcgtc tctaaaatcc cattattttc ctaagacaga
     6241 gactgaaaca acagatgttt atttggaccg tttggtgaaa accttatcgg agacgacagc
     6301 cactaaaagg gggcttgtcg tggaaaacga ttggttggct attcagctga ctcaaaaaat
     6361 cacacaggta ggcttatcta ttcctgatca agtcgctatt gtaggctttg ataatagtca
     6421 agcctcccgt ttgttgagtc ccaaattaag cacagcagct caagattttt accaaatggg
     6481 gcaagaagca gctaaagtct tgttgcagat tattcatgag ccagaccaag cagtggtgtc
     6541 ttgccagtta cctgttcaag tatttatcag agaaagtagt cactaaaaaa gacgttacta
     6601 gcatgagctg gttagctcag gtaaaggaga ccagaaatga ccatttatca cgccttaaag
     6661 gattatcaag aagtcatgac aagaggagac tatcttgtct ttgacacgcc attgacttgc
     6721 cgatttattg gccgtttttt ccgctttgaa aatcaaaaag ccctgctggc agaattggca
     6781 acgtcaaagt attttcagtg gattgaagaa ggccaagcag aggtgacgat gaaacacttt
     6841 tttaaccgtc agctggctaa ggatgccttt accctgaagg tttcagaaga taaggaaatc
     6901 attattgaaa gccaaaacct tagaggtttt cgttacgccc aagaagcttt gcttaaagtc
     6961 atgaccttca aaggggataa actttatttg cccattgttt ctgtcaagca cagcccatca
     7021 tttcctatgc gggggataat tgaaggcttt tatggaacac cgtggacacg agaggaacga
     7081 atcgattgcc tacgttttat tggaaataaa aggatgaata cttacatgta tgctccgaaa
     7141 gatgatgatt accagcgaaa actgtggcgc gatctttatc ctgaggattg ggtgacttat
     7201 ttcaaagagc tacttgcagt agccaaggaa gaagggattg atttttggta tatgattagt
     7261 ccggggcttg attttgatta taccaaggaa gctgactatc agttgctcta tcaaaaattg
     7321 caacaacttc tagcgttagg tgtttgtcat tttgggcttt tgctggatga tattgactac
     7381 caaattgtag atgctgttga gagacgattc aaaaagactg cctatgccca ggcccacttg
     7441 gcaactgagg ttcatcactt tttaaaccaa caacatgcgg cgccagaatt ggtgatctgt
     7501 ccgacagaat acgacaacca ccatgattct atctatttgc aagagctgtc agaaaggatt
     7561 cctaaagaag tcgccttttt ctggacaggc ccaagcacgc tagcgagtca aatctcgcaa
     7621 gcagatattg aaactatggc agcagtatat caacggccta tcattatttg ggacaatatt
     7681 cctgttaatg attatcaaaa agatccagaa cgtctctttt taaccccttt tgccaatcgc
     7741 tcgccatttt tatgccagcc agactatcag gtcaagggga ttgtttctaa ccctatgatt
     7801 agttgggaat tatctaagct taccttgaca gatatgagcc attatctgtg ggatgctaac
     7861 cgttatcagc ctagtcattc ttggctagaa accttaacag actatacaga agatactgaa
     7921 ttagccttag ctttacaggc atttgcttgg cataatggca atcgtcatct gcacagggac
     7981 cttccttttg aagtggaaga agctctcctg gctaaggatg tatcaacgtt atcagcttgg
     8041 gtagatgaat tggtcgaacg tgtcaatacg ttgagaaagc tagataagcc agcgtttcaa
     8101 caagctattg ctccttggtt tgaacgggtg gccaaagacc aagatttttg gcaggctatg
     8161 ttaaatcagg agcctcagtt ggaaacactc tatgctgact tacaagaaga taaacaccgt
     8221 attggaagtg acattccaag tcgttactat cgcatctact atcaacagca agataaacta
     8281 acagctaatc aaggtcaagt tacccaagca agaccggaag actatgctta gcatacgagc
     8341 tagaaaggaa tgatatgtta gcatttccaa aagagttttg gtggggagga gccacctcag
     8401 gccctcaaag tgaggggcgt tttgctaagc agcaccgtaa tctctttgat tattggtatg
     8461 aagaggagcc tgacttgttt tacgattacg tgggacctga tacggcttcg gatgcctatc
     8521 atcagattga atctgatttg accttgttag cttcactagg tcacaattcc taccgcacct
     8581 ccattcagtg gacacgtttg attgatgatt ttgagcaagc gacgattaat cctgatggcc
     8641 ttgcttatta taatcgagtg attgatgctt gcttggccaa tggtattcgt cctgttatta
     8701 atttgcatca ttttgacctg ccaattgccc tctatcaagc ctatggtggc tgggaatcaa
     8761 agcatgtcgt ggacttattt gtcgccttta gcaaggtttg ttttgagcag tttggtgatc
     8821 gggttaagga ttggtttgtc cacaatgaac ctatggtcgt tgtggaaggc tcttatttaa
     8881 tgcaatttca ttaccctgct atcgtggatg ggaaaaaagc agtccaggtc gcctataatc
     8941 tagccctagc cacagccaag gttattcaag cttacaggca aggtccagca gaacttagtg
     9001 atgggcgtat tggaaccatt ctcaatctga cgccagccta cccagctagt caatcagaag
     9061 cggacatggc tgctgcgcat tttgcagaac tttggaacaa tgacttgttt atggaagctg
     9121 ctgttcatgg gaaattccca gaagaattgg ttgcggtatt gaaaaaagat ggggttttgt
     9181 ggcaatcaac gccagaagaa ttggctctta ttgctgagaa tagagtggat tatttgggat
     9241 tgaattttta ccatcctaag cgcgtgaagg ctccggatgt cattccagtg attagcccat
     9301 cttggagtcc tgaatggtat tatgatccct acctgatgcc tggccgccgc atgaacgtgg
     9361 ataaggggtg ggagatctat cctgaggctg tctatgatat tgccatcaag atgcgagacc
     9421 attacgacaa tattccttgg ttcttatctg aaaatggtgt agggatttca ggagaagagc
     9481 gttaccgtga tgaaactgga cagattcaag atgattatcg catccaattt ttgaaagaac
     9541 atttgaccta cctccacaaa ggaatagaag caggctcgaa ttgttttggt taccatgtat
     9601 ggacaccaat tgatggctgg tcttggctca atgcctacaa aaaccgctat ggccttgtgg
     9661 aaaataatat ccatacccaa gtgcgacgac ctaaagcttc agcttattgg tttaaaaaag
     9721 tagctactca taaccgcttg atttcattag aagtaatgga ggagtttgga ggctctgctt
     9781 ctcacctcag tgattgaacg tgtgaccgtc tcctttgaga caagtgaata atgatgttac
     9841 caatgattaa acaagggcct ttttcctcat gttaagagga tcgaggctct tgtatttctt
     9901 tggaaagtgt tggtatttgc cgaactagat ataagcgttc tgtctggttt ggcatcatct
     9961 atccaccttg ggtaatttgg ttcttcaatt ctttagagta tcttggctaa ggatgcttgt
    10021 ttttcatctt ggtattttag gattttcttt catatttttg gaccagataa aagcccctca
    10081 tggtttctag tgactgtttg ttatgtcact gtccacgata aggggactat atgagtgagt
    10141 tattaagtga ggctttgctt attggcgata actagcatag cttctaatag ctcgagcatt
    10201 aactgatgac caatgccttt aacagaagcg tcagcaacaa cgacatcaac aaagggacca
    10261 ggcatcaggc tgtgttcatc agcagagagt catttaggca gaaagccagt atcgttgtag
    10321 ctaatcagca atccttttag gatgtctttg tagatgtcag aggcgattag ggacaatagg
    10381 ggataagagg gatttagcgg tccatggtta ggcctccttg tgttcttggt aaaaatcaat
    10441 ggcagctcca agaagattgg cttcgttttt aaagtgacaa atggctaatt ggggtctaag
    10501 gtcggagatt tcgacggctt ggtagagttt gtctagttca gcttcaatcg ctgacagtag
    10561 aaagtcagct tgggaaacac cacccccgat taaaatcagt tgaggatcaa aggcgtgttg
    10621 aatgttaaaa ataccgatgg ctaaactttg gagaaagacc tgcctttctt tgagtgctag
    10681 gggatctcct tgttctgcga gggcaaggac agctttgcca gtataatctt ttccgttatt
    10741 gacgattgca ctatagcgct tggccatatt taccactgtc cctaactgac taaaggtttg
    10801 gtagcggtcg ttcatgatca tgaacccaaa ttcgccccca aataagtggg caccatggta
    10861 aatcttgcca tcaatgacca agcttcctcc aactccagta ccaagaacga gcatggctag
    10921 gctactagcg ccttttcctg cgcctaaggt agcttcagct aaggcggcac aattggcatc
    10981 attttcgata gaaatagggt aatgtagccg ttcttctaag gcctcttgta ttttaaaatg
    11041 gtgaatgtag ggaatagcgc tggcgccttc gataaccccc ttttctttat tgactgcccc
    11101 aggtgaactg atggcaatac ctgagaaatg gtaagcagag taacgagcaa cttcttggtc
    11161 gagtaattga taaaactttt ccagactaga gggcgtggga aagctgcttt gctggcttaa
    11221 ttggccattg tgacagaggg caaatttaag ggaagtgcct cctatatcaa tacataacaa
    11281 gctcatgagg tgttctcctt tattatagta gaatagacga tcatgtctca tcttagtatg
    11341 acagatttaa gcaacaatga aaaggctttc taagtgattc tatactttgt gttattatac
    11401 ctataatttg ttgctttcaa ataatgaaag cgcttgatat actgtaacta taacgtgatt
    11461 aacacaaagg gaggttggga aatgacaaga cagaccaaca aaaagacatc cttttggaaa
    11521 aatgtgatta aataccgggc cttattatta atggtattac caggtttcat ctggttcatc
    11581 tttttctttt atattccagt tttagccaat gtggttgctt ttaaagattt tcattattca
    11641 gcagggggct ttatggaaag tttgaaggag agcccttggg ttggtttggc taacttcaaa
    11701 tacctctttg cttccaaaga tgcttggttg attaccagaa ataccatcgc ttacaatgtg
    11761 attttcttac tttttaatgt tttctttgcg attgcttttg ccattatcat gagtgagtta
    11821 cgaaataaga gaacggttaa ggtctatcac accatgtcct tattgcctta tttcttatca
    11881 tgggtggtta ttgaatactt tgtttctgcc tttttaaata cggataaagg tttcattaat
    11941 cagctcttga ctggaagtgg agcagatcca atcaagtggt attccaatcc cacttggtgg
    12001 cccttgattt tacttttcat gagtgtctgg aaggggctag gctacaatag cattatctac
    12061 tatgcttcag tcaaagggat ttctgatact tattatgaag ctgctatggt ggatggtgca
    12121 agcaaatggc aacaaattag gaacatcacc attccacaat tattgccaat gatgtctatc
    12181 ttattgatca ttaatattgg taatattttt aaatctgatt tcggactttt ctacgttatt
    12241 cccaaaaatt caggtccact ttatgacgtg accagtgtgt tagataccta tgtctacaat
    12301 gccttgactg ctacaggaga tattgggatg gcatcggcag ctagccttta tcagtcagta
    12361 gttggaacca gcatcttgtt agtcaccaat gcgattgttc gtcgcatgga ccctgatgca
    12421 gccttgtttt aggaggaaaa catggagaaa aagaaaaaag tcgaaaaggt taatgttaga
    12481 acctttgatc gaaaaaccaa tgctatcttt aatattctga ttggtctgtt tgccatctct
    12541 tgtatcattc cttttatctt cgtgattatt atttctttca ctgatgaaag ttacttgatt
    12601 aatcatgggt atagtttttt tccagatgtc tggtcaacta aggcttacca gtatattttt
    12661 caaggagcca tgtcccatag aatcatgagg tcatttggga tatccgtgtt tattacagtg
    12721 gtgggaacct ttattaacac gaccatgaca tcaacctatg cttatgcgat ttcaagacct
    12781 tattttccat acagacgttt ttttactgtt tatgcactta tcaccatgct ctttgcacca
    12841 gggatggttg ctaattactt ggtggttagc aatctccttc atttgaagga tacggtttgg
    12901 gccttgattt taccaatggc tctgggccca tttggcatct tggtcatgag aacgttcttt
    12961 aaaaagacag ttccagatag cattattgag tcggctcgta tggatggggc tagtgaatgg
    13021 atgattttta tgaaaattgt tctccccttg gctgttccag ggattgccac catcagttta
    13081 ttttctgcct taacttattg gaatgattgg tttaacgcct tgctttatgt gcaaagtgag
    13141 aatctttacc caatgcagta cttactgatg aaaattcaga gcaacctaca ggccttggca
    13201 caaaatgctg gcatgagtgc acaaatggca gatagcctag catcgctgcc aaaagaatca
    13261 gttcgtatgg ctatcgtggt tattgcaacc ttgccgattg ccttgactta cccattcttc
    13321 caaaagtact ttgtcggtgg tttgaccatt ggtggggtga aggaatagga cttaaggaac
    13381 tggtcacaag accagatttt atctaatcat tagtaacaaa agaaaacatt ttttaggagg
    13441 cttcacttat gaaaaagtgg caaaaaatcg tgtgtgtgac tggaactgtg cttgcagcgt
    13501 ctagtctagc agcctgcgaa agcaagtcag catcaaagga tagtgatgtc aaattattga
    13561 tgtaccaagt tggtgacaaa cctgataact tcgatgaatt gatgacaatt gctaacaagc
    13621 gcatcaaaga aaaaacaggt gcaacggttg accttcaata catcggttgg ggggactggg
    13681 atgataaaat gagtaccatc attgcctctg gtgaaaacta cgacattgct tttgccaata
    13741 attatgtggt caatgcacaa aaaggtgctt ttgctgattt gacaacgtta atgccaaaat
    13801 acgctaagaa aacgtataaa aacttagacc cagcctatat taaaggaaat actattgacg
    13861 gtaaactcta tgccttccca gtagatgcca acgtttatgc ccaacagatg ctttctttca
    13921 ataaagaact agtggacaaa tatggccttg acatttcaaa cattaagtcc tatgcagatg
    13981 ctgaaaatgt cttgaaacaa ttccacgaaa aagaaccaaa tacagcagct tttgctattg
    14041 gtcaagtctt tagtatgtca ggtgactatg actacccatt aaccaaaacc caaccctttg
    14101 ctgtgaaaat tgatgaaggc aagccaacca tcattaatca gtatgaagat gagtccttta
    14161 aaaacaatct ccgcttgatg cacaaatggt ataaagaagg tttgattcca acagatgcag
    14221 cgaccaatac agaaggttat ccccttgaag gaaacacttg gtttatgcgt gaagaaaccc
    14281 aaggtcctat ggactatggc gatactatct tgaccaatgc tgcaggaaaa gacatcgtgt
    14341 ctcgtccatt gactaaaccg ctaaaaacca catcacaagc acaaatggca aactttgtgg
    14401 tatcaagcgt atctaaaaac aaagaaaaag cagttgaagt cctttctctt cttaatagcg
    14461 atcccgaatt gttaaatggg cttgtttatg gtgtcgaagg caaagcttgg gaaaaaattg
    14521 gcgacaagaa aatcaaactg ctcgatggct atcaaccaaa aatgcacatg ggtgcttgga
    14581 atactggtaa caataaaatc ctttacactc aagaatctgt cactgacgac atgattgcta
    14641 aacgtgacca atcaatcaag gatgctaaag aatctccaat ccttggtttc actgttgaca
    14701 caaaagttat caaaacggaa ttgtcaaata tttcaaatgt catgaaccga tataaagcaa
    14761 gtatcaatac tggtacagtg gatcctgacg aagcccttcc aaaacttctt gcagacctca
    14821 aaggtgctgg ttgggacaag gtgcaaaaag aagttcaaaa acaattggac gactttgtag
    14881 ctaaagacaa gtaaggcatt cattttcttg attataagtt gagggctggg aaatctcagc
    14941 tcttttcttc tgatgagtgg aaaaaacgga tcatcaaata agtggaagtt ataaagggag
    15001 aaaaattaat gtcaataatg ttactactct tagtaaagcg gtttccaaaa gcctataaag
    15061 tgtgctatat tagaagagtc taaactatta atcagagtaa aactaatacc agcatcttac
    15121 tgggggtgct aaaactagtc tcgtagctgc tggtccctga aaccgctata agtgttaaca
    15181 agaaaaagag gattatcata tgaatggcat tgaaaaaacc tgctttttaa tttggaaaat
    15241 gatccaattg accctcattt ttcatctctt gtccttagct ggactgattg tgtttggggt
    15301 ggggccagcc tggcaaacca ttgtcaccct atttttaaaa acacctcaag aagaaaacca
    15361 ctattctttg aaaagggctg ttcaactttg gaaatcttat ttcaaagaag ctaatctaag
    15421 atttggtctt tttgccctga ctttcctttt tttaaccttt aatttgcatt gggcagtaca
    15481 gtttccatcc ttgttttggt ttaccgtgtc tttcttgatt gtaatagcca tggtttggct
    15541 aaccatgacc tatctttaca tggtttttta tgcagtgagc tatgagatta acctttggaa
    15601 taatatgaaa ttagccttta tcagcgtctt tttaagtttc aaatcctttt tactcatgct
    15661 gagtgttttg ctgggaatta tcttagtgac ttggcaatac aaaggtcttt atctcttttt
    15721 aaccttcgga gctctagtct tttgcttgga ctttgtcact aaggctaatc gtcgactagt
    15781 agatggagtg attgatgagt gttaaaacat tgggaaggta tgtgactaac cactttaagc
    15841 agggtttttt gattaatcga ctgatgaaat tatatagcct gctaattgta agttttttca
    15901 ctttagcagc tattggcttg agcagttatt ctattagtag tacttataaa agggtggatg
    15961 ctgaggcgca gatgcgactg gaggagactc taggtagatt gcagttacaa aacgatatta
    16021 ccctacgggt tttaggccag ttggttggcc gttcagaaga ttaccataat ctctatcaat
    16081 acatgacgtt aaccccaaac caatattttt caaacgtttt tgaagactgg gaaaaaggaa
    16141 aagacacggt cctattttct gaagaggtga ggcgtctttt tgacttgtac cctgatgtga
    16201 cttctatgac cctactgcta gaggacagta gtgcttatct gtacgccgat agggtcatta
    16261 agacgggtcg tttgctttat agcaagcctg aaaaagtaac cggaaatgtt ttagttcgct
    16321 ctattcgaaa tccagaatca ggagatgtga caggtcgtct ttacctgacc tttgacaaac
    16381 cactgacttt ggtagagaca cagcaggatc actatttagc tacttttgct tttgattact
    16441 atggccgcaa actcttccat caaggaggtc ggagatttcc tcatttagag gctgaggtta
    16501 aaaaggctat caaggcagat cgggcagctg atcttagtaa tctcagcaag gcttatcgga
    16561 tgcagtacaa tcgctcggga gacctcttag cttatgtggc tgtcagaaaa tcctatttat
    16621 tagcggaagc tgtcaggaca gtttttgtgt atggccttgt ttctctactc ttagcttggc
    16681 tgttattgca gttgctcttt agggttttcc gaaattatat ccagcaggtt tctgaaatta
    16741 cggatactgt tgaaatggtt gcagcaggcg atttgtcttt aaccatcgac aacagccaca
    16801 tggaattgga actgtatcat atctcagaag ccattaatca gatgttggcc agcattaaag
    16861 cttatattga cgaagtttat gtgttagagg tagagcaacg agatgctcaa atgagagcac
    16921 tgcaatctca aatcaaccct cattttttat acaacacgtt agagtatatt cggatgtacg
    16981 cccttagttg tcaacaagaa gaattagcag atgtcattta tgcctttgcg agtctgcttc
    17041 gcaacaatat tagccaagat aagatgacca ccttaaaaga agaactggct ttttgtgaaa
    17101 agtacattta cctttatcaa atgcggtatc cagatagctt cgcttatcat gtaaaaattg
    17161 atgagagtat tgctgactta gccattccta aatttgtcat tcaacctctc gttgaaaatt
    17221 attttgtgca tgggattgat tatagtcgcc atgacaatgc actaagcatc aaggctttag
    17281 atgagacgga tcatctcttg attcaggtgc ttgataatgg acgtggtatt agtcaagagc
    17341 gcctagcaga tatggaaaga aggcttcaag agcaccaaac aacaggcaat agctctattg
    17401 gtttgcaaaa tgtttacctc cgtctctttc atcattttcg agacagggtt tcttggtcca
    17461 tggctaagga gccaaatggt ggctttatca ttcaaattag gattagaaag gatgcttgat
    17521 gtataaggta ctattagttg acgatgaata catgatttta caagggctca ccatgattat
    17581 tgattggcag gcacttggat ttgaagtggt tcaaacagca agatcaggca aggaagcctt
    17641 agcctatttg actcagtacc cagtggatgt catgatttca gatgttacca tgcctggaat
    17701 gacaggactg gatttaatag aagcagctaa aacctatcat cctcagctac aaaccttgat
    17761 tttatctggt tatcaagaat tctcctatgt gcaaaaggct atggaattag aaaccaaggg
    17821 gtatttgcta aaacctgtgg ataaggcaga attacaggct aaaatgaaac aatttaaaga
    17881 ctggttggat gcccagcagg cagaatcaat ccggcaagaa gcttatcatg acagcctttt
    17941 gaccctttgg cttacagatg aattgagtga gaaagaattt cagcagctaa gtcaaggctt
    18001 gccagcggct gctttaactg gttttacagt gctgtatttg gactgtcaag agtggcaagc
    18061 agccatcgat gcttattttg aacgagaagg tcagcctttt tacctcaaaa aagaagaaga
    18121 taagaaggtt tatctggctg tcctacttgg taaaactgat caagccaagg catttaccta
    18181 tgatctacaa aagcgattct caagaaacat gcatcaactt attttgggag aaacagttga
    18241 tgactgggaa aatgtttatg aaagctacaa tcaggtgctt aagagcctct tttacaattg
    18301 tgaagtgtca ccaattagag caaaagataa gtccaaaatt gaactaccag agtcccgttt
    18361 gcagttcttt gcttttaaca aggcgttgat gattggggac gaacctacaa tcttgtctaa
    18421 attagaagct atttttgacg agatgaagac cttgaacttt tcaccagagg atgtgaagca
    18481 tgtttcgttc ttgttgtttt ctgacattta ccgtcaattt cccattttag ataaaatgac
    18541 ttatctgtcc atggtaaaaa ctattcatga cagccaatcc attgatcgca ttttgaggga
    18601 actaaaaaaa gtgttggatg tcaccaatca gaacaattcc cctgaaaaac gctattcaga
    18661 tttagttagt gaaaccattg attgcattcg caaggaatac catcaagaat taacccttaa
    18721 agctatcgct gataggttac atgtcaatgg ggtttattta gggcaatgct ttaaaaatga
    18781 aaccgagcgt agttttaccc agtacttaaa tcatgttagg attcaaaaag cgcaacagtt
    18841 attgctttac accaaccaat ccatcaatga aattgcttat gaaacaggtt acaataccaa
    18901 tcattatttt atcaagatgt ttaaaaagtt gaatggttta tcgccaaaag agttcagaga
    18961 tcgttacaag gacaattacc aagccatcaa gggcgatcag taacgttaaa caggagattg
    19021 atatgacacc agatagcaag gagcagacag tgactggcta ccaataccac tatattgatc
    19081 aagaaggaag aaagcagccc tttaatcaag gctggcgttt tcttatggca gatgtggcgt
    19141 gtgctcagga cccttctttt gatgattcga actggcaggt gattcattta ccacatgatt
    19201 tcagtcttaa gcagccttac acaagaaatg gtgaagctga aagtgcttat aaattaggtg
    19261 gtgtcggttg gtatcggcat tatctcgtgt tagatgaggt tttagctggt tgtcatgttg
    19321 ccattacttt tgagggttcc tatatggaaa cggaaattta tgttaatggg caattcattg
    19381 gcaaacactt aaatggctat caggaattta cctatgatat ctctgatgtt gtgacttttg
    19441 gagctgaaaa tcttctggct gttcgggttg aaaacaaggt tcccagttct cgttggtatt
    19501 caggcagtgg tctttatcgt gaagtgagtt tgtctgttct tccccagctt cattttgtgg
    19561 cagaccaggt agcaatgacc ttggctgata ctgctgtgca ggagaaaggg caacagaaag
    19621 ttgatttacg ctttgccctt aatcagtcta ttcagacttg ccactaccaa ttgagcctct
    19681 gtttatggga acaatcacat tgctcaaaag acaagaaact cctttatcaa gaaacagaag
    19741 tgcctctagc tgatttggct ttccaaagac agtatggtct tacactgtct ttggaagaac
    19801 tccaattgtg gtcaccagat aatcctcacc tctacgattt agaactcact ctttactatc
    19861 aaggtcaggt cattgattgc ttttgccttg aaactggttt tcgtcagctg acttttacgg
    19921 ccaatcaggg gctttttgtg aatggcagag ctgtcaaatt aaagggagtt tgtttgcatc
    19981 atgaccaagg aggcctagga gcttgtgctt acgaagatgc cctagccaga caattagtcc
    20041 tgttgaaaga catgggggct aataccattc gtagcaccca taacccaagt agtcccaaac
    20101 ttaggcaact agccaatcgt ctcggctttt ttgtgattga agaagccttt gacacctgga
    20161 cctatgccaa aaatggaaat gttaatgact tttcaaacta tttccatcag actatcggaa
    20221 ctgaaaatgc aaactatctt caaagagtga ggtcacctga aacgagctgg gcccagtata
    20281 gtattgaggc catggtctgg tctgccaaga atgacccgtc agtgttgatg tggtcgattg
    20341 gtaatgaatt gatggaaggt ttttcagccg atgtcagtca ttacccagag ctgacaagac
    20401 aaatgtgcca atggattgct gctattgaca cctcacgtcc cattaccttt ggggacaata
    20461 aattaaaaga agctgacttt tgctggcatg aggaagtgtc gcaaatggca actcttctta
    20521 gtcaattaga ccatccccag ggactcattg ggttaaacta tgctaatgga aaagactatg
    20581 ataagcttca tgaggagcac tctgattggc tgttgtatgg ttctgaaaca gcctcagcca
    20641 ttaccagcag ggcttattat aaagagacaa aaaaagttct tgactccggt tatcacctaa
    20701 cctcttatga tcatgctaag gtcgattggg gtgccttcgc tagccaggct tggtatgata
    20761 ccattacccg tgattttgtt gctggcgaat gcgtttggac aggctttgat tatttaggag
    20821 aacctacccc ctggaacaag atcgacagcg gtgttgtagg cctttggcct tctcctaaaa
    20881 atgcctactt tggcatttta gacacggcag gctttccaaa agatagctat tatttttacc
    20941 aaagtcagtg ggcgcagggg cagaccacct tgcacctgtt accagtctgg cagaaggacc
    21001 agctttgttt tgatgagcag ggattggtgg aggttgtggt ttatagcaat gctgccagtg
    21061 tgcaactgat gtttgaagat gagcagggca acttaacaga ttatggaagg aaggcatttc
    21121 atacttatag cacgccaacg ggacacactt atcagcttta ccaaggagct gacgctgcta
    21181 agaatcctca cgagaatctt tacctgactt ggcgagtgcc ctatcaaaaa gggttgctaa
    21241 gggcagtggc ctacgacatt tctggtaaaa gcattccaaa aaccagtgga cgttctcagg
    21301 ttagaaccta tggttcagtg gcaaagctat cttggaaagc ctttgaagca cctattgacg
    21361 ctccttggga attgctttat ctggatttat cactcttgga tagccgaggt gaattggtca
    21421 gccatgctca agattggcta aaggttcaag tagaaggacc agcccgtttg ttggctcttg
    21481 ataatgggaa tccgactgac cacacccctt atcaggagcc tctacgccag gcatatgggg
    21541 gaaaattatt agccatttta gccctcactg gagaggcggg acacattaag gtcacggcaa
    21601 aagcctcgca gcaacttagc agtgtttttc agacacaagt agcctgccgt gcccccaaag
    21661 aacacttagt gacactacct ttagagaaat atcagtttaa aaagagccga ctgacaagtc
    21721 aacaagaaat tggtcaatct tgtctaaaga ccacacaatt cctttctgtt ttggagaaca
    21781 aagacaccca gcaaaaagca ggtaaggcta gcacacctca cattcttatc accagttacc
    21841 agcactattt acctctgccc ttgcaggttt gttctcaggc atttgatttt aaaaaaggcg
    21901 atgatatctt cttgcctcag tggctccaag tcaaagatgc ccaaggttct tttgtgaaaa
    21961 aagcttttcc aatgacatgg tacctaaaag agaaaatctt tgccaagcct attcttgtca
    22021 cgggctatgt ttcttgtttt gggcaatcaa taccggttga ggcaaggctc aacctagcac
    22081 aagctagcaa aagacggcac caggatctca gtttagtcgc caagcaatcc ctggccgcaa
    22141 gtcaaaaaag gctaacttat tgctaccaat atgatacggt gcaagccata ggagccatta
    22201 gcttgcaaaa tcacacaggc acatctctta gtgtttctgt ggcaatcagt tatggtagtc
    22261 agagctctat taagcaagaa accttgatgc tagctgatag ccacttgagc cagttagaag
    22321 aggttatttt cttcgatgat attttgactg ttttgtatct ggcagtgacc cttgaagtca
    22381 ttgaaggacc tgacctaact gaagacagta ttcaaattgg cctttgggat ttagcatgaa
    22441 gcatgagtaa aagaagactt ctttggcacc aggtctgatg aattctgtaa aataaggtat
    22501 aataaaaaac aaataggcgt cctttattac gtgaaaggcg cctttacaag gttgaaatgg
    22561 aaagtgagat ttctaaatgt cagaacgttt atcaggccac accctgttgg tctctttgct
    22621 tgctacccct attcgtcata gtttgtctcc caaaatgcac aatgaagcct atgctaaact
    22681 ggggctggat tatgcctacc ttgcttttga agtagggaca gagcaattag cagatgccgt
    22741 gcaagggatt cgtgccttag gaattcgtgg ctccaatgtg tctatgccaa ataaagaagc
    22801 tattttaccc ttattggatg acttgtcccc agctgctgag ttggtcggtg cagtcaatac
    22861 ggttgtcaat aaggatggta aaggacatct cgtggggcat attacagacg gcataggagc
    22921 gctcagagcc ttggctgacg aaggagtgtc ggtaaagaac aaaatcatta ccctagcagg
    22981 agttggtggg gctgggaaag ctatcgctgt ccagctcgct tttgacggcg ccaaagagat
    23041 tcgtttattt aaccgacaag ctacacgtct aagtagcgtt caaaagcttg tgacaaaact
    23101 gaaccagcta acaaggacta aagtaaccct tcaagacttg gaagatcaaa atgcctttaa
    23161 ggaggccatc agggaatctc atctatttat tgatgctaca agtgtaggaa tgaagccttt
    23221 agaaaatcta agtttgatta ccgaccccga gctcattcgc ccagacttgg tggtctttga
    23281 catcgtgtac agcccagcag aaaccaagtt actagccttt gcccgtcaac atggcgccca
    23341 aaaagtcatt aatgggctag ggatggtgct ttatcaagga gcagaagctt ttaaattaat
    23401 cactggtcaa gacatgccag ttgacgctat taaacctctt ttaggtgatg agtaactcaa
    23461 ccctttttaa agaacttttt aagtaagctt aattatgata tattaataag agatggagca
    23521 gtcatcatgg gctgctaaaa ttctttttgc gagagctgtt tttaagagca aaaagcttat
    23581 ttgaagagcc ttatccctaa cgtgatacaa gtcatagttc ctttgaggtc tgccagataa
    23641 cctaccgttt ttttagaaaa gaagctctta taaaaggaaa agttcaatga ataaaggaga
    23701 atagcaatgg taacaaagga agttgggcat gactttttag cacgtctagg aaaaaaacgc
    23761 ttaagacctg gcggtgttga ggcgacaaac tggttgattg aacaaggaca attctctcag
    23821 gattgtcacg ttttagaggt tgcctgcaat cgctgcacga cagcaataga gttagccaaa
    23881 accttcggtt gtcagattga tgccgttgac ttaaacccca aggttgtcaa agaagcacaa
    23941 gaaagggttg ctgttgaggg gttaacccgt cacattacag tatcccaagc caatgcttta
    24001 tcactaccat ttccagataa ccattttgat attgtgatta atgaagccat gttaaccatg
    24061 ttgaacgccc aagccaagga gaaggcactc aatgaatatt ggcgtgtgtt aaaaccaggc
    24121 gggcgacttt tgacacatga cgtagcttat gaagatccaa aaacaagaca agtacttgac
    24181 gagttacgtc aaacgattca tgtcaatgtt gctcccttgt cactaacagg ttggcaagcc
    24241 ttatatcaag aacacggttt ttctcaagtg acttatcacc atgggaaaat gtctttgatg
    24301 acacctcgtg gaatgattaa ggatgaaggt cttatgaaca ccctgaacat tatgagacga
    24361 ggccttaaga aagagaacag acaacagttt ttaaagatgc gtcgtttttt taccagaaca
    24421 ggcaaaaatc tctactatat tgctgtaaaa agtgtaaaat aaaccttaga ccaacctgtc
    24481 catacaacta aacagaccat agaggagttc gaagatgtct tatatcaata atattgagca
    24541 cgcgaaggtt cttgatttga cgcaagaagt aatgattgag caagatcaaa tgttaagtag
    24601 aacactagtc caaaggcaag acctaggaat aacagttttt tccttagata agggccaaga
    24661 aattgggcga cactcatcac caggagatgc catggttact atcttaagtg gcttagcaga
    24721 aatcaccatt gatcaagaga cctaccgggt tgctgaaggt caaaccattg tgatgccagc
    24781 tgggattcct catgccttat atgcagtaga agcctttcaa atgcttttag tagtagtaaa
    24841 accggaggct taacatgatt gaaaatctct ctcaattggt gcaatatcat gatcatcagg
    24901 tggctagccg atccttgagc cgtctactgg gattatctca atctattgtt ttatatgcca
    24961 tggcccaagg agaaagcatt agtcaagaga ctagtccaag agataaagta atacttgttt
    25021 tagaaggtca gctcattttc gatttagagg atcaaaaaca ggtcctaact caagaaagtc
    25081 tcatagccat acctgcccaa aaagtccatc atttagaagc taaaaccgat tgtaaactat
    25141 tacaagtgat tttagattaa gggcttattg tcaactgtat tgggtggcct atggaaaagc
    25201 aaaagagaag gtgacgctca tcttctcttt ttacgtattc aaagcgatga caatacgaat
    25261 tttaaagctt ggctttctca tctccagatt aagcccttta gcttggttta ttttagaatt
    25321 cactaaaaaa accttaatga gtttcctatc tccttatagg tttctcatta aggcttttta
    25381 gacgaaataa ttgaacgaca ggcaaaagaa agatcttttt acgagtgata ccgttctcct
    25441 atagttccat aaatcctctt tttgatgttg ctgttagtta ttcttagcta aaagttatat
    25501 tgttatcaag acttgtcttg tagtaacatg ttttaggagt tccaggatac cgttattctc
    25561 ttagcaagct taactagcta gagtggagtc actatttata ataaactgtc gagcttctcg
    25621 acaaattggt gatcgtcttt gttaatggct agggtggtaa aaccggtttc tgtgggtaat
    25681 ataaagataa tatgttgctc agaattcttc ttatctgttt taaagacgtc aaagagggat
    25741 gtcgcagaga catcagctct ttcaagtgtt gttggtaact ggtaacgttc aaaaacttga
    25801 aggaggctat ccaagtcctc ttttggcaag agccctttgg aaacagccag tttagcatca
    25861 accaccatac cgatagcaat ggcttcaccg tgatggtaaa aatcatggta gcagagcgat
    25921 tcaattgcgt ggcccaaggt atgcccaaaa tttaaagaca tgcgcaaacc attttcaaat
    25981 tcatcttgtt caacaatccg ttttttattg gaaatggatt ggtaaatcag acgttcaagt
    26041 ccctgcttat cggtttcttt ttgaaaatca cgtaactgct gaaaaagcgg tctatcatga
    26101 atgaagccga ttttgagcat ctcactgatg ccgcaggaga attcccgttg cggtaaggtc
    26161 tccaaaaagg tggttgaaat aatgatagct tctggagggt aaatgctacc aatcatattg
    26221 gttagacctt taaaatggac tccaactttg cccccgatac tgctatccac ctgactaagt
    26281 aaagtcgttg ggatttgaat gtagggaata ccacggtaat aggttgcagc gacaaaacca
    26341 cccagatctc caacaacacc accaccaata gtaacaatca tatctttttt ggaaaaattt
    26401 tcagcgatga gctggtcgta gatagcactg acgcgttcca aggatttgga ttgacctccc
    26461 ggggggcaga catggacaaa agcgttgtat tgctgagcaa attcttcaaa gagagtctga
    26521 tacaagtggt agaccgtttg atcggtgata aacaagagtt tacgctgctt gcgctcacca
    26581 aggcaatctg ctaaggtttt taaaacatgg tcggtaaaca ggatatcata atccttgacc
    26641 cgagaatgga catgaagtgt ttgtggcata agcactcctt tcatcagtac taggtaacag
    26701 agataacgca gtgatattta gagcttaatc ttgccaaagt tcctgcccca actgttctaa
    26761 ttgcttataa tcaatttgct gggcagcatc tgacagcgca tggtcgggat caggatgaac
    26821 ctccatcatg atgccattgg caccgacagc cttcgctatc ttagcagcag gtaagagtaa
    26881 atctcgtctg cctgtcgaat gagacacgtc cacaataatc ggtaaatctg tcttttgttg
    26941 aataataggg actgccataa tatcaagcat atttctagtc tccacatcgt agccacgaac
    27001 gccacgttcg cataagataa tgttagattt tccagtgtct tgtaagtagg aaagggcgcc
    27061 caaatattcc tcgatagtag ccatcaagcc tcgtttaaac aaaataggct tatcgatgtg
    27121 tgacaaggtt tttaaaaatt caaaattttg catgttgcgg gcaccaacct gaatgacatc
    27181 gagatagtca taggcttctt ctaattggcg ctcggacatg atttcactga ccgatagtaa
    27241 gccaaattcc tgacaaacct catgcaagta acgaattcct tgcaggccaa ggccttgaaa
    27301 agaagcagca gatgttcttg gtttataggc gcctcctcta aaatagttgt aaccaagttt
    27361 tttggcactt gaagctgcta atctaatgtg atcataagat tcaatggaac aaggtccaac
    27421 aataaaatta ttcttagaac aagtcttatt ttgaaagtca gacataatgt caatcattcg
    27481 tttgattcct ttactaattc tgtatggcgt gctctatggg ataacgtctt atttaggaat
    27541 acaaaatctc gttgttatcc atgaagcacc cttagcctgt gaaatgatac cataaacaag
    27601 atgaaatagc aagtaaaccc tagattgtct atgttcttag tcatttttat taaaaaaggc
    27661 ttactagcta taaaaaaata ctgccctaaa tcttattagg acagtatttt ttatagatgc
    27721 caccaccgag aatcgaactc ggaacgaagc attaccattg ctttattata ccatttaact
    27781 acagcggcta cctttttata atactataag ttattaattg atgcaagctt ttcttaaaaa
    27841 tatttcctta attgtttatc atcaaaatga gagtaccagt tattaataac atggcacaag
    27901 aggcctgcct tatggtataa tggtaaagat gatttcagaa agaggaagcc aagcatgtct
    27961 tatgaaaaag aatttttaaa agattttgaa gattgggtta aaactcagat tcaagtcaat
    28021 cagctagcca tggcaaccag tcaagaagtt gcccaagaag atggcgatga aagggctaaa
    28081 gatgccttta ttcgttatga aagtaagtta gacgcctacg aatttttact aggtaaattt
    28141 gacaattata aaaatggtaa agcctttcac gatattccag atgagttatt tggagcaagg
    28201 cattattaag aaggagacac gaaatagtgg caaaacaaaa aaatcgtaaa aaagcattga
    28261 aattagaaat gaagcgtaat ggcttgttaa aaaaagcagg tcaagttttt gataaggcag
    28321 ttgaaagtgt tgaaacagct gtggataaaa ccatttctgc tggtaaaaat cttgtggaaa
    28381 aaggcagcca aacggttgaa aacctgacag caagcaagga aagacttact cttgatgagt
    28441 ttgcagggca gccagttgta gctggtatcc gctctgacct tgtcgaaacc ctatatgcag
    28501 aaggcatcca ttcagcgcaa gcttttaagg agtggacaga aaaagacctc cttgctctta
    28561 agggcattgg cccagcaacg gttaaaaaat tggtcgaaaa tggcgcaagc tttaaaaaat
    28621 agtcatcttc tcgttgctta atggctataa atttgttaga atattagcaa tcagaggtgc
    28681 attgagttgg tctgttacag agagcggtgg tgttgagaaa tccgcacaga tgtcaaggct
    28741 agtagctgag gatcagaaat cagatatgaa aagtagcaga cccattttat ggtctgaaac
    28801 agtggtggta ccgcggaaat cgtaacacga aattcgtccc tgtctaggtt atctaggcag
    28861 ggattatttg gtttcatttg aaagaagatg atggcttatt gttaaaatgt tgttagaagt
    28921 atataataga aaaactttgc ccaaagtgga aacagaacgg ctgctattac gtcaacgaaa
    28981 aggggacaag gcattgttcc agaagcggct tcagctctga ttgaaattgg ttttacctta
    29041 cttgatttgc ataaaattga gctgggttgc tacgactaca acaagcaaag tcaggcagtg
    29101 gctcgcaaat taggctttac cttagaagcc aatgcccgtg accgtaagga cgttcaaggt
    29161 cgccgctgtg gcgacatgcg ttttgggtta ctgagaagtg agtgggagga gcagaaacaa
    29221 aaatgaacct tatcatcatt ggtgctcaag cgtcgggcaa gatgaccatt gggcaagaag
    29281 ttgccaggca gacaggcatg actttgtttc ataatcacga ttctattgac tttgttttac
    29341 ggtttatgcc ttggtctcaa gagagcactg ccttgattga acgtatccgt tttgcttttt
    29401 ttgaaacctt tgctaagaca ggtcaagaca tgatttttac tattgtaatt gacttcaatg
    29461 atccaaatga tgtagcaatg cttgaaaaga ttcaggctgt ttttcagtct tatgaccaag
    29521 aggttctcct tgtcgaatta aaaacagata tagaggaacg tcttaaacgc aatcgcacag
    29581 aaaatcgtct caaacataaa cctcttaaac gcaacatcga gtggtcagaa caagatattc
    29641 aatccacgat ggcatatgct gtttttaatc cagaagaacc acccaaaacg ctcacgtatt
    29701 accaaaaaat caataatacc catctcaccg ctgctgaaac agcgcagctt attatccaaa
    29761 aaatgactca tatcaaggag aactaagatg acagaactat cacctaaata caatcctgcc
    29821 gaggttgagg caggtcgcta tcaaaaatgg cttgatgcag atgttttcaa gccatcagga
    29881 gaccaaaaag caaaaccgta ttctatcgtg attccaccgc caaatgtgac tggtaagttg
    29941 cacttaggac atgcttggga cacaacactt caagatatta tcattcgtca aaaacgcatg
    30001 cagggctttg atacgctttg gttgccaggg atggaccatg cagggattgc gacacaggct
    30061 aaagtagagg agcgtctgcg cgagcagggg atttctcgtt acgaccttgg tcgtgacaaa
    30121 ttcctagaca aggtctggga gtggaaagac gaatatgcca ctacgattaa agaacagtgg
    30181 ggcaaaatgg gtctttctgt ggactacagc cgtgagcgct tcacccttga tgagggcttg
    30241 tcaaaagcag ttcgcaaggt ttttgttgac ctctacaaaa aaggctggat ttaccgtggt
    30301 gaattcatca tcaactggga tcctgctgcc agaactgccc tttctgacat cgaggttatc
    30361 cacaaggatg ttgagggagc tttctatcac atgaactata tgttggaaga tggctcacgc
    30421 gcccttcaag tggcaacaac gcgaccagaa accatgtttg gagacgttgc cgttgccgta
    30481 aacccagaag atcctcgtta caaagatttg attggtaaac atgttatttt accaatcgtg
    30541 aataaattga ttccaatcgt gggagacgag catgccgacc ctgaatttgg gactggagtt
    30601 gtgaaaatca cgcctgctca tgaccctaat gactttgagg ttggtcaacg ccataatctg
    30661 ccacaagtga atgtcatgaa tgacgatggc accatgaatg agttagctgg cgactttgca
    30721 ggcatggacc gttttgaagc tcgtcaagct accgttgcta aacttgaaga acttggtgcc
    30781 ctagtaaaca tcgaaaaacg tgttcactca gtaggtcact cagaacgttc tggtgcagtc
    30841 gttgagcctc gtctatccac ccaatggttt gtaaaaatgg atgagcttgc taaacaagct
    30901 atggacaacc aagaaacaga tgaccgagta gatttctacc caccacgctt taatgatacc
    30961 ttccttcaat ggatggaaaa tgtccatgac tgggtaatct ctcgccaatt atggtggggt
    31021 caccaaattc ctgcttggta caatgcagaa ggtgagattt acgttggcga agaagcacca
    31081 gaaggtgatg gctggactca agatgaagat gttcttgaca cctggttctc atctgcttta
    31141 tggccgttct caactatggg gtggcctgac acagatgtag aagatttcaa acgttatttc
    31201 ccaacctcaa ccttagtaac aggttatgac atcattttct tctgggtgtc acgtatgatt
    31261 ttccaatcgc ttgaatttac cgggcgtcag ccattccaaa atgtcctgat tcacggtctt
    31321 attcgtgacg aagaaggacg caaaatgtct aaatcattgg ggaacgggat tgatccgatg
    31381 gatgtcattg agaaatacgg tgccgatagc ttacgttggt tcctctcaaa cggctctgcc
    31441 ccaggacaag acgtgcgttt ctcatacgaa aaaatggacg cctcttggaa tttcattaat
    31501 aaaatttgga acatttctcg ctatatcctc atgaataatg aagggttgac attggaagaa
    31561 gctgaaagta atgtggctaa ggtagctgcc tcagaagctg gaaatgtgac tgaccagtgg
    31621 attctccaca atctcaatga aaccatcgct aaagtgacag aaaactttga caagtttgag
    31681 tttggtgtgg caggacacat tctttacaac tttatttggg aagaatttgc caactggtat
    31741 gtggaattga ccaaggaagt gctgtatagc gacaacgaag ctgagaaagt tatcacgcgc
    31801 tctgtccttc tttatacttt ggacaaaatc ttgcgtctcc ttcacccaat catgccattt
    31861 gtaaccgaag aaatctatgc ccaatatgcc caaggttcta ttgtgaccgc agcataccct
    31921 acggttactc ctgcttttga aaatgaggct gcgcataaag gtgtggaaag tctgaaagat
    31981 tttatccgtg ctgtacgaaa tgcgcgtgca gaagttaacg tggcaccatc aaaaccaatc
    32041 accattttgg tgaagacagc agatagtgag ttggaagact tcttcaccag caacgtgaac
    32101 tacatcaaac gtttcaccaa tcctgaaaaa ttagaaatca gctcagccat tgctgcgcca
    32161 gagctggcta tgaccagcat catcacaggt gctgaaatct acttgccact agcagatttg
    32221 cttaacgtgg aagaagaact cgctcgccta gataaagaac tggctaaatg gcaaaaagaa
    32281 ctggacatgg tcggcaaaaa actcggaaac gaacgctttg tagccaacgc caaaccagaa
    32341 gttgtccaaa aagaaaaaga caaacaagcc gactaccaag ccaaatacga cgcaacccaa
    32401 gaacggattg cagagatgaa gaaaattaaa tcatagtgtt tagaacgcag ttgaaaaact
    32461 gtgttctttt cttactaata gagatattag attgaagttt aattatgaga aaaacgcttt
    32521 ctttatttaa agagttatgt tacaatacta ttacaatcat cgtacaaata gtgttatttt
    32581 gaggggcata tgagaatgat tttagcacac tatgactgta aaaaagataa aaagcaatct
    32641 ttagatgagc atttatggca tgtggcctgt tctagtcgac aggaagcatc tataattggt
    32701 caaggagatg tgcttttttt aattggtctt taccacgacc tgggcaaagc tgatcgaacc
    32761 tttcaagata aattattaaa taatccaaat cggcatgttg atcactctta tgcaggggca
    32821 aaatacttat gttctattat tgggcctcat ctaaaaaacc gaggggttga taaaaatgag
    32881 agaatgacat tcaacgaaat ggtggggtat gtcatctctg ctcatcatgg gatgtatgat
    32941 ttatgctact attttgacga tgctgaatat tatggcttta ataagtttaa aaatcgtatc
    33001 aatagagact tagatggtta tcactatcat gaagatatta aagggtacgc tctaaaatta
    33061 gaaaaaaaat tatgtgatta tggctacaaa gatttaaggg agcttattga taaagctttt
    33121 gataattacc aacaagccat gtcttcctta aactggcaag ataagagtga gtggaattat
    33181 tatcagtctt gtatggtgag actttacttg tcactcttaa aaaacgctga tattttggac
    33241 acagtaaatg cctatggcct taagataagt cctatggata aaacagagcg atcctttcta
    33301 aaacactcct atttagcggc cattgaacaa aaatatgcta gctttggaca gccaaacaat
    33361 cagttgaaca ctattcggac agaaatcgct gagcgtgtta aagaaagagg taaacgagat
    33421 tccaaaggga tttatcgctt agatttaccg acaggagctg gcaagactaa tcttagtatg
    33481 cgttatgcgt ttcaccaatt agttcatcac gacaaatcaa ggttttttta cataacgccc
    33541 tttctttcgg ttcttgaaca aaatgcttcc gaaattagaa aagttacagg tgaccttggc
    33601 gtcctagaac accattccaa tgtggtgaaa caggctaatg aagatgatga tgacaaggac
    33661 agtttattgt cagcttatct tagtgatagc tgggacagtc aagcagtctt gacttctatg
    33721 gttcaatttt tccaaacact tttcaaaaca aaatcagcta atctgagacg tttttcaagt
    33781 ttgattaata gtgttgtgat tctagatgaa gttcaatccc tgcctattga agtcaccact
    33841 ttgtttaatt taacgatgaa ttttttaaat aaagttatgg atacaaccat cgttctttgc
    33901 acagcaacac aacctgctta tgattcttca gagattgacc atcgtatctg ttatggaggg
    33961 aacttgggag aattagctga aatcgttgag ttaacgattg aagaaaaaca gattttttca
    34021 aggacagagc ttagaaaatt tgatgatagt gatcagaaag ttcacttgac tgatgttatt
    34081 aaccttattc taggtgagga aaactcagtt cttgctattt ttaatacgaa aaaaacggtt
    34141 cataactgct atactatgct aaaagacatg actgatagac cggtctatca gctttcgaca
    34201 aatatgtgtg cgcagcatag acttgacttg attgctaaga tcaaaacgga gttacaaaat
    34261 aatatcccta ttatttgtat tagcacgcaa ttaattgaag caggtgtaga tgttgatttt
    34321 catcgcgtca ttcgttccta ctcagggatt gattctattg ttcaggctgc tggacggtgt
    34381 aaccgagaag gcaaacgaga taaagggcaa gtcactcttg tcaatctgac caatgaagag
    34441 gaaaatattt ctaggctgac agaaataaaa gctaaaaaag aagccacaga atctattctt
    34501 cataagattg ggtctccaat tgatatctca actttaaacc gtgacttttt tgagtattat
    34561 tatgccaata atcagggact gatggattat cctttggaag acaacctatc aatctacgac
    34621 tatttaagcc ttaatattta tcagacggca aataaaaagt tcaaaggtaa gttaaaacaa
    34681 gcttttaaaa cagcaggagc caaaatgaac ctcatcaata atgacatgat aggaattctt
    34741 gtatcttatg gcgaagctga gaaaaaattg gcttatttag aagaattagg tgtgtcacat
    34801 tttttatcag caaaagatta tcaaacgata aaatcattac taaaagagtt acaacctttt
    34861 acggttaatg tccgcgagaa cgatcctctc cttgatgcaa caaaatcttt tctaaatggt
    34921 caggttctgg ttttgacgtc ggagtattat gacacagaaa gaggagttaa atacgattca
    34981 gctaactttt acttctaact caaaacgaaa gcagattaac gaaaggttgt tagaggacct
    35041 tgttaacctg ccaatcatca ttagtaatta ttatcaattt agactattta ataaaattag
    35101 attacaaaaa aacagaagga ggaaagtagc ttgtacagat ctagagactt ctacgtgaga
    35161 gtaagtggtc agcgagctct ttttacaaat ccagccacaa aagggggatc ggaacggtca
    35221 tcctattcgg ttccgactag acaggcactg aatggtatcg ttgatgccat ctattataag
    35281 ccgaccttta ctaatatcgt cacagaggtt aaggttatta accagattca aaccgaatta
    35341 cagggtgtca gggctctgtt acatgattat agtgcagatt taagttatgt atcctatttg
    35401 agtgatgttg tttatctgat caagtttcat tttgtttgga atgaagatag aaaagatttg
    35461 aactcagata gacttccagc taaacatgaa gccattatgg agcgttctat tcgtaaaggg
    35521 ggacgtcgag atgtgttttt gggtacaaga gaatgtttag ggcttgtaga tgatatcagc
    35581 caagaagagt atgagactac tgtgtcgtat tataatggtg tcaatatcga cttgggaatc
    35641 atgttccatt cctttgccta tccgaaggac aaaaagacac cattaaaatc atactttaca
    35701 aagactgtga tgaaaaatgg agtcattacg tttaaagcac agtctgaatg cgatattgtt
    35761 aacacgcttt ctagttatgc ttttaaagca ccagaggaga taaaatcggt taacgatgaa
    35821 tgcatggagt atgatgccat ggagaaagga gaaaactgat ggattttttt acttctctct
    35881 tgaagactta tgaaaaagca gagctagcag acttggttga tcatcaaaaa agaaataatg
    35941 agccggtttt actgccgatt tatcatacga gtttaaagtc aaatggtaaa aatatcattt
    36001 cagtgaaact tgacaaagat ggccagtttc acaaggcaga atttatggca gataagcaaa
    36061 tgattatttt tcctgtaacg gctgattctg ttgctaggtc aggtagtcat cctgcaccgc
    36121 atcccctagt cgataaattt gcttattata gtgctgaaat ggggcagact cagtatgatt
    36181 cttttcataa gcaactgaat aactggattg attattgtga ggagggtgat gtcaagaaat
    36241 ttttaacctt tgttcagcag ttcattttga agccagaatt tctaacattg attcttgatt
    36301 ctttaattgg tcctgattat caacataatc aattaaaagt cacattttgt gatgccactg
    36361 gaaaagaaaa attaattgat ttatcagctt gctttttaga attttcaatt gatcagttcc
    36421 agggctttaa aaatgaatcg gtttcgacat ttaaagcctt acaccaatcc tatatttctt
    36481 ttgttgaagc caatcgtgaa aatctcggta tttgtaatat tagtggacga gaggaacagc
    36541 ttaccgataa gcatagaggt ttgatgggga atgctaaaat catctctgtt agtaataaaa
    36601 gagaagctta taaaggacgt tttagagaac gcgaagacgt ttttagtgtt ggctatgaaa
    36661 cttccgaaaa gattcattta atgctcaagt accttttaga aaataaaaat accagtactt
    36721 ggttagggtc ttctcaatat ttaatcaact ggttcagcga tgatttaaca aatgatagtc
    36781 ggttggatat tgtatcacca atctttgatg atggacttga agaagatgat gatgacgata
    36841 cgcctcctgt tataacatta gcaactgaag acaataaaag aattggtaaa tcattcatca
    36901 agggacaaaa attatttgct aatgatgcca cttactacgt tgctattttg aataaaacca
    36961 gcaatgggcg gattgcttta aaatattttc gtcagcttca agcgtcccaa ttactcacca
    37021 atcttaacaa gtggcaggaa acatacagtt gggagtcgcg atctaagttt gggaaaagtc
    37081 gcttaagaac ccctactttt catgacatcc ttaatgtgtc ctacggggtt gatagggatc
    37141 gcttccttga attagataat gataacttca aaagtgatca aattcaaaag ttagtggcaa
    37201 gtttgattga tggtaaaccg atgccacagt ccattgtcaa aaagttaggt aacaatgtta
    37261 aagaacgaca tcgttaccat aagcactggt atcaagttga gcaggtctgc ttagcaattt
    37321 tacacaaaca aaatggggag gaattttcac cgatgctaga tcataccaat caaaatcgtt
    37381 cctatctttt tggacgatta ttagcaattt ttgaattaat cgagaccttg cgttatggct
    37441 tggatggaaa caataacgac cgtattacca atgctgaacg ttattggaca gcctatactg
    37501 gacaaccaac aaaattgatg atgttattgg aaaataaaat taagccttac gaagaaccat
    37561 tgaaattaaa tcgtcgtggc agttggatga aattagaaaa agaaaaagaa gagattttag
    37621 aactgttaaa tcctctgtta gaaacagaaa caatggaaaa acccttagat taccgcttta
    37681 tttttgggta ttatgctgag aaaaactatt actatacaaa acaaaacacg gaagtaacag
    37741 aaagtgagga gtaaaaagat gttggaacac aaaattgatt ttatggtaac tcttgaagtg
    37801 aaagaagcaa atgcaaatgg tgatccctta aatggaaaca tgcctcgtac agatgccaaa
    37861 ggatatggtg tgatgagtga tgtctccatt aaacgtaaga ttcgtaatcg tttgcaagat
    37921 atggggaagt ctatttttgt gcaagctaat gagcgtattg aagatgattt tcgttcactg
    37981 gaaaaacgct tttcgcaaca ttttacagct aagacacctg acaaagaaat tgaagaaaaa
    38041 gcaaatgcat tatggtttga tgttcgtgct tttggacaag tttttactta tctgaaaaaa
    38101 tcaattgggg tgcgtggacc agtttccatc agtatggcta agtccttgga gccaattgtc
    38161 atttccagcc ttcaaattac gcgtagtacc aatggtatgg aagctaagaa taatagtggc
    38221 cgctcttctg atacgatggg gacaaaacat tttgtagatt atggtgtgta tgtacttaaa
    38281 ggttctatca atgcttattt tgctgaaaag actgtttttt ctcaggaaga tgctgaggct
    38341 attaaagaag ttttggttag cttgtttgaa aatgatgcgt cgtctgcacg tccggaaggc
    38401 tctatgcgag tttgtgaagt cttttggttt acgcattcaa gcaaattggg aaatgtttca
    38461 agtgcgcgtg tctttgactt gttagagtat aatcaatcaa tagaagaaaa aagcacttat
    38521 gacgcttatc agattcatct aaatcaagaa aaattggcta aatatgaagc gaaagggtta
    38581 acgcttgaaa tcctagaagg actctagtat ggtctatgcc gaagatgatt atttaatgct
    38641 atcaggtatt cagcatttcc aattttgtaa acgtcaatgg gcgttgatcc atattgagca
    38701 acaatggctt gataatgaag cgacagcgca tggacaggtt ttacatacta aagcagataa
    38761 cccttacatt aaagaaaaac gaaaagagct tttggtctca cgtgctatgc ccatttcttc
    38821 tgcagaactt ggactttcag gaattatgga tgttgtggaa ttttataaag atgatcaagg
    38881 tgtgtctttg aggggaaaac gtgggaaatg gttaccaaaa gttgtggaat acaagcgcgg
    38941 aaaacctaaa aaagatacca gagatattgt ccagttggtg gctcagacca tgtgtttaga
    39001 agaaacgcta gactgcgaca ttaacgaagg ttatctttat taccatagtg tcaatcaaag
    39061 agtgattgtt cctatgacat cagctttgcg tcaagaagtg aaggaattag ccgcagagat
    39121 gcatgaggtt tatcagagtc aaatgctacc taaagcagct tattttaaaa actgtcagct
    39181 ttgttcttta gtcgatattt gtaagcccag gttgagtaaa aaaacaagga gtgtgtcgcg
    39241 ttacatcaat gaggctatga ccagtgagga gatggaccta tgaagaagtt gctaaatacc
    39301 ttgtatttga cgcaagaaga tttttatgtc actaaagagg gcgataacat tgttatcaag
    39361 caagaaggta aggttctcaa acggtttccg tttcggatta ttgacggtat tgtctgtttt
    39421 tcttatttgg gtgtgtcgtc tgctttggtg aagttatgta cggagaatca gattaattta
    39481 tcgtttcata caccacaagg gcgtttttgt ggtcgctata ttggttcaac caatgggaat
    39541 gtgttgttgc gtagagaaca ttatcgttta tctgatcgtg aggaatcttt ggaatacgca
    39601 aagcggttta ttttggctaa aatttccaac tcaaggaaat acttgctacg ctttaaacga
    39661 gatcatcgtc aacagattga taccaagctt tttgaggctg ttaatgacga attgatatgg
    39721 gctttagaga tggttcaggc agcagataat aaagactctt taagagggat tgaaggccaa
    39781 gctgctaatc agtattttcg catatttaat gacctggtgt tgacggacaa aaaaacgttt
    39841 tacttccaag gtcggagtaa acgaccatcc ttagattgtg ttaatgccct cttgtctttt
    39901 ggttacagtt tactgacctt tgaatgtcaa tctgccttgg aagctgtcgg attagacagt
    39961 tacgttggtt tctttcacac ggatcgtcct gggcgtgcta gtttagcgct tgatttagtt
    40021 gaagagttcc gctcatatat tgtagatcgt tttgtctttt cattaattaa taaaggacaa
    40081 cttcagaaaa aacactttga ggttaaagaa aatggtagta ttttattgac ggaaaatggc
    40141 agagctattt ttattgattt gtggcagaag cgtaagcata ctgaggtaga acatcctttt
    40201 acaaaagaga aagtaaaact tatgttatta ccctatgtac aagcgcagct tttagctaag
    40261 gccatacgag gagatttaga aagctatcca ccttttatgg tttaggagat gttatatgat
    40321 ggttttagtc acttatgatg taaatacgga aacacctgct ggtagaaaaa gattgcgtca
    40381 tgttgccaaa ctctgtgtgg actatgggca acgtgttcaa aattctgttt ttgaatgttc
    40441 tgtgacaccc gcagaatttg tggatataaa gcaccgctta acacaaattg atgagaaaac
    40501 tgatagtatt cgcttttatt tattggggaa aaattggcag aggcgtgtgg aaacacttgg
    40561 tcgctcagac agctatgacc cagataaagg tgtcttatta ttgtaaaaat ctcttgtgcg
    40621 aagctagctt tcacagaaaa accttgcttg ctcgcgcaaa aataacttaa aaaagaagcg
    40681 aaatggagat aaaaaggctt aaaacacctc tatgtgtgcc atccgtttct ctataaactg
    40741 tgtcatttgg cgcagtctca cccttcatgg gtgagtggat tgaaataact gatctcgtcc
    40801 aaaagtcaaa aaagaaagga gtctcaccct tcatgggtga gtggattgaa atttttaaat
    40861 cgacatgtgc agtaccagtg tcatcttgtc tcacccttca tgggtgagtg gattgaaatc
    40921 ataagttgag ccacagactg gtttgggcta ttgagtctca cccttcatgg gtgagtggat
    40981 tgaaatatca gctagctcgt tgagtaggcc gttgagctcg gtctcaccct tcatgggtga
    41041 gtggattgaa ataatagatt acttgcttta agtgataaca ggacactgtc tcacccttca
    41101 tgggtgagtg gattgaaata tttagtcgcc aactttaact atgatcaaac ttggtctcac
    41161 ccttcatggg tgagtggatt gaaattctga agttaagacc ttgtccagaa gccaaaccaa
    41221 ggtctcaccc ttcatgggtg agtggattga aatgtcgata atggcttgat gatcacctga
    41281 gaaagtgtct cacccttcat gggtgagtgg attgaaattg tccgcatacc ttgatttgag
    41341 cgagtaaact cgtctcaccc ttcatgggtg agtggattga aattccattt tttactttct
    41401 catgtggcaa aacataatgt ctcacccttc atgggtgagt ggattgaaag atgaacccga
    41461 tctctctttt aatgaggtcg ggtttttaca tgcctttagt caaccattta tctgatagcg
    41521 tatcaaattc aagtttttgc atgttctagt ctatggtttg cgccactagc tttcggtaaa
    41581 ctaagggtaa cttaagagag gagttattta tgacactatc acttgtatta atggtatcgg
    41641 tttttggggc aggcttgtta tcctttttct ctccgtgtat ctttccggtc cttcctgtct
    41701 atttaggcat tttactggat gcagatgatt caaagacgat tactatattt ggtaaaaaac
    41761 tctattggta tggcattgtc aaaactttag cctttatttt tggtctatct actatttttg
    41821 tgattttagg ttacggggct ggttttttag gaaatatcct ttatgcggta tggtttcggt
    41881 acttactggg agccttggtc attatcttgg ggattcatca gatgggcctc attaccatta
    41941 agagcttaca atttcaaaaa tcactgactt tccataataa caagaatcgc aacggtttgt
    42001 tcaatgcatt tatccttggt ttaaccttta gctttggttg gacgccttgt gtgggacctg
    42061 ttttgagttc tgtcctagca ttggtggctt cagggggaaa tggtgcctgg caaggtggcg
    42121 ttttgatgat tatttatact cttggattgg gcattccttt cctactcatc tcttttgcgt
    42181 caggcattgt tttgaaacag tttaacaagc tcaaacccca catactttta ctgaaaaaag
    42241 taggaggcgt tctgattata gtcatgggaa tcttgcttat gacaggaacc ttaaataact
    42301 tagcacaact ttttggataa aggagaaaca caatgaaaaa aggactatta gtaacaactg
    42361 gtttggcttg tctcgggcta ctaactgctt gctcaaccca agacaatatg gctaaaaagg
    42421 aaataactca ggacaagatg agcatggcag ctaaaaagaa agataagatg tcaacatcaa
    42481 aggacaagtc catgatggca gataaatcat ctgataagaa aatgaccaat gatggtccta
    42541 tggcgcctga tttcgaactc aaaggcatcg atggtaagac ctatcgctta tcagagttca
    42601 aaggtaaaaa agtttatttg aaattttggg cctcttggtg ttcaatctgt ctatcaacct
    42661 tggcagatac cgaagacctg gctaaaatgt cagataaaga ctatgtggtc ctaacagttg
    42721 tctcgccagg tcatcaaggg gaaaaatcag aagcagactt taaaaaatgg ttccaaggaa
    42781 cagactataa ggacttacca gtcttgttag atccggatgg caagctattg gaagcttacg
    42841 gtgtcagatc ttacccaaca gaagttttca ttggaagtga tggtgttctt gctaaaaaac
    42901 acattggtta tgccaaaaaa tcagacatca aaaagaccct taaaggtata cattaggaag
    42961 gaccagctga taggcattag aaaaaaggag ttgagtttat ggaacataaa tggaaattat
    43021 ggctatttat cgttggagtg gtcttgttaa taggcggagc ttctgttctc attcagaaag
    43081 gtcaagccaa ggcttttagt caaggcaagc ctcaactacc agctaaaaaa gtcaaatcca
    43141 ctaaagtaga tcccaatgcc cctgttgatc aaaaagtgat ttacctggct ggaggctgtt
    43201 tctggggcgt tgaagaatat ttttcacaag tggatggcgt tctagatgcg gtgtcaggct
    43261 atgccaatgg tagaggcgat accaccaact accagttaat tcatcagact ggtcatgcag
    43321 aaaccgttga agtggcctat gatgcgaacc gtattagctt gaaagaatta ttactgcatt
    43381 ttttccgaat tattgaccca accagtctta ataagcaagg aaatgatcgc ggtagtcaat
    43441 accgaactgg gatttactat actgacaaag cagatttagc tattattgat gaggtcttca
    43501 aagaaaaagc taaggattac aagaaaaaaa tagtggttga aaaagcacca ttgaaacact
    43561 ttattaaggc agaagactac caccaagatt acctcaagaa aaatccaaat ggctactgcc
    43621 atattgacat caaccaagcg acttatcctg tgattgatga aagcaagtac ccaaaaccaa
    43681 gtgccactga gatcaaggaa aaactatctg cagacgaata ccgagtgacg caaaaaaacg
    43741 aaactgaaaa agctttttct aatcgctact gggattcttt tgatgcagga atttacgtag
    43801 acgttgtgac aggagaaccg cttttctctt caaaagacaa atttgaatca ggttgtggtt
    43861 ggccaagctt tagccgcccc atcagcccag acgttgtccg ctacaaggaa gataagagtt
    43921 tcaatatgac gagaacagaa gtgcgcagcc gttctggcaa ttctcatcta gggcatgtct
    43981 ttactgacgg acctaaagac caaggcggcc ttcgttactg catcaatagc ttgtctatta
    44041 cctttattcc aaaagctgat atggaagcta agggctatgg ttatttatta tcatctgtag
    44101 aatagggtta ggcctaaaaa tctgatataa tagaagaaag actagtatga gagggccatg
    44161 caaggccttt ataaagataa ggagacaccg tgtgtactca ttgttaattg tagaagacga
    44221 ataccttgtg cgccagggta ttcgttcttt ggttgatttt agccagttca agattgatcg
    44281 ggtcaacgaa gcagaaaatg gccagttggc ttgggacttg tttcagaaag agccttatga
    44341 tattgttttg acggatatca atatgcccaa attaaatggg attcaactgg cggagttgat
    44401 taaagagcat gcgcctcaga cccatttggt ttttttaacc ggttatgatg actttaacta
    44461 tgctttgtct gctttgaagt taggggcaga tgattacttg ctcaaaccct tttccaaggc
    44521 cgatgtggaa gatatgttag gaaagctccg gaaaaaatta gaactttcca agaaaacaga
    44581 aaccatccag aaattggttg agcagcctca aaaagaagta tcagcaatag caatggctat
    44641 tcatgagcgg ttggcagatt ctgatttgac cctaaaaagc ttggctcagc agcttggttt
    44701 tagccctaat taccttagcg tcttgattaa aaaagagtta gggatgccct ttcaagatta
    44761 tctggtacaa gaacggttga aaaaagccaa gcttctcttg ttaaccagta accttaaaat
    44821 ctatgaaatt gcagaacagg tcggttttga ggacatgaat tatttttctc agcgctttaa
    44881 gcaactggta ggcgttaccc caagtcagta taaaaaagga ggccaggcat gaagcgttat
    44941 cccctactgg tccagttgat ttcttatgtc tttgtgatcg taattgccct cattaccacg
    45001 cttggtttgc tttattacca gacgagttct cgtaatatca ggcaactaat tgaacgtgat
    45061 acccggcaga gcattcggca aagttcccaa tttattgacg cttacatcaa gcctcttaaa
    45121 gaaacaactt cggtgctggc gaaaaattcg gaaattcaag actttgctag tcaaattcat
    45181 caagaaaatg acaagcaggt tcttcagctc atgaagatgg ttcttgcgac caattccgat
    45241 ttacaagcag ctgttctggt gactaaggat ggtcgaacgg tgtctaccaa ttctcagttg
    45301 attatgaaaa cctccagtga tatgatggca gaaccctggc ataaagcagc catagaccgt
    45361 caagccatgc cagtcttgac cccagctcgg caattatccc tttcttctaa aaaagaatgg
    45421 gtagtttctg tgacccaaga ggtagtggat gctgctggtc ataatttagg cgtgctaaga
    45481 cttgatattg catacccgac tattaaagcg tctttagatc agcttcagct aggccgccaa
    45541 ggctttgcct ttattgtgaa tgataagcat gaatttgttt accatcccaa aaagagtgtt
    45601 tacagttctt ctaaggagat ggctgcgatg aagccttatt tagcgattca gaatggttac
    45661 actaaggaca agacatcttt tgtttaccaa aaactcattc ctaacagtca atggacttta
    45721 gtgggagtgg cgtcactgga tcagttgcac cgggtgcagc gccaaatttt ttggtccttt
    45781 cttggaacag ggcttctagc ctgtcttatc tgtggcctta cgactatttt agtcttacgt
    45841 aaatggattc gtcccattca acaattgcag caagttattc ttgctattca aaaaggagat
    45901 cgtcagttac gtgcccaaga aacgggttct ccagaattga cagaccttgc ccaacagttt
    45961 aatgcgctct tagatcaaat tgatagcttg atggttgccg ttgcggataa ggaaaaggcg
    46021 attgggcagt ataggttaca agccttggct agtcagatta acccgcattt tctctataac
    46081 accttggaca ctattatttg gatggcagaa tttaatgaca gcaagcgcgt ggtagaagtg
    46141 accaagtctc tagctaagta ttttcgtttg gcccttaatc aggggaacga atacattcgt
    46201 ttggcagatg aactggatca cgttagccaa tacctcttta ttcaaaaaca gcgctatgga
    46261 gacaagctaa gttatgaagt gcaaggctta gatgtctacg cagactttgt tattcctaag
    46321 cttatcttac agcccttagt agaaaatgct atctaccatg gcatcaaaga agtcgatcgc
    46381 aagggcatga tcaaggttac ggtatctgat acagctcagc atctggtgtt gactgtttgg
    46441 gataatggta aaggcattga agactcttca ctgaccaata gtcagagctt gttggctagg
    46501 ggaggtgtgg gccttaaaaa tgttgaccag cggttaaaac ttcactatgg tgaaggctac
    46561 cacatgacca ttcatagcca gtcagaccag ttcactgaaa tacaattaac ccttcctaaa
    46621 atgcatgaat taatggcaga cgacacacag gaaaatgagt aaggttacag gaagtgcatg
    46681 tcagccattt ccctaagtta gggtattgga gataagaacc ttagaaagga tatcatgagt
    46741 ttagcatctg actattttag ccgacagacc cccatagttg aaaagctaat ggcttacggt
    46801 tttgaaaaac gaaataatgg ttacttctat aacgaacggt ttatggaaga agaatttgag
    46861 gcgcagctta ggattgatga ggctggcaat atctgggatc gggttattga ttgtgacttg
    46921 gaggaggatt atttgccttt acaacaagca gcctggcaag gaacctatac tgggcaggtt
    46981 agagcagcct atttggaact cttggagcgc ttatcagtag cctgttttga agtcactcct
    47041 tttcagtcaa tgcaagctaa tagacttgct aagcatatca ccaaagaatg gtctgaccca
    47101 atggactatc cttttgaaaa gcacccagac cttgcaacct atcgggtagg gggcaaatgg
    47161 tatgctatga ttttttctct cttggctgat aaattagacc agataccaga gagattagta
    47221 ggacagacat gtgaagtgat gactgtcaaa gttaatccca aggatttccc tcagttactg
    47281 cagcaagaag gcatttaccc agcgtatcac atgtcaaaga aaaactggat tagtattatt
    47341 ttggatgata aggtaacaga tgataagctt tggacgttag tgactcaaag tcgtcaacta
    47401 gtcaacccaa acggtctttc taatcctaat ggtcctgatt attgggttat tccagctaat
    47461 ttgaaatact atgatattga tgcagaattt gcagccaatg atgtgatttt atggacccaa
    47521 aaagctggta ttgccgtgag agactacgtg ctgatttata taacagcccc agtcaaatcc
    47581 attcgctatg tctgccaagt tctagaaact gatataccta acgagggtta tcgtaaaaat
    47641 cctaacattg acaaactcat gcgtctccga aaatgccaac agtacaagga tggtctcttg
    47701 tcttttgacc ttatgaaaaa acatggcgta gctgcagtga gagggccaag acgattaagc
    47761 cctcaattaa ttgcattttt aaaggaaaaa gagtatttta aagagaacaa ctaaaggaga
    47821 ataagagatg gttgaatttg tagcagatca aagtttttgg gaactttttc caggtgccaa
    47881 actaggtgtc gtcttattaa aggatgttca gaaccaagca gagtcaccag aagatgtcaa
    47941 acagctctta gcagacagcc atgagttagc aaaagcttat ttaacagcag acaattttag
    48001 tgataatcag gtggttcaag tctaccgcaa ggcctatcaa cactttaaaa ccaaaaaagg
    48061 agctcgctct agcattgaag cccttctcaa gcgggtgtca aatggtcaaa gcattccgtc
    48121 tattaaccca ctagtggata tttataatgc ggctagtcta cgttttggtt tacctgctgg
    48181 agccgaagat agtgacagtt ttatcggaga tttgcgtctg acgataacag atggtggtga
    48241 cgacttttac ttgattgggg atgctgacaa caacccaacc ttgccaaatg aactctgtta
    48301 taaagatgat attggagcgg tttgtcgttg ccttaactgg cgagatggcg aacgcaccat
    48361 ggtgacagaa cacaccaaaa atgcatttct gattatcgaa gctcttgatc aagaaggtca
    48421 aaatagattg caagaagctc tgaaattcat tgaaggcagc gcaaaaatgt accttcatgc
    48481 aatcacttct gtgcatgtgt tggataaaga caatccacac gtgccacttt ttacagaaaa
    48541 ctagattagc aggatgagct gtgtaaaata gaaggttaac aaaaaagcga gtaaacgaat
    48601 gtcctgttct ttaggttttc gtttactcgc tttttgatga gatcttactg ctgccctagt
    48661 aaaaggtgag gatgaggtcg tatatcacat agaggttttc tgttaagcct tatttgttac
    48721 taaagaagaa tggtggtgtg taatgactaa gggtctcgta acaagccttg gcttgctcat
    48781 tgtcttcaca gacaatcaag caagtatcat caccacagat cgttgctaca atttctggaa
    48841 tttgcatggc atctaaaatg gagccaaagg attgggctag tccaggtaac gtttttaaaa
    48901 taatttgatg ttgaactatc tttaacatga ccaaagcgtc ttccatgtaa aaacgaagcc
    48961 gatgttccca gcgggtttgt gaaatggcta acgcttcata gtgtgtatcg tttccagaag
    49021 ttactttgac caggttcaat tccttcatgt cacgtgatag ggtagcctga gtaatcgtga
    49081 tgccattttt ttgcaaccgt tcttgtaatt cttgttgtgt atgtatagtt gtctcagaga
    49141 tgagggaacg tatgagttgg tgacgcgtct ctttcttatt cattgttata atcttccttt
    49201 aacgtaattg ataacaatcc gagtatagca aaaagaggag aaggtgtaaa gtttttgatg
    49261 aaccgcttac aaaatggctt ttttatggta aaataaagat gatgtttaga aaaaggagat
    49321 ttgtgtgatt cgaagagaag attatcaata ccttagaaaa ctaaacgatt ttcgctactt
    49381 ttctattgaa caatttgaca aaattgtagg gcagatggaa ttccgaaaag ctaaaaagga
    49441 ccatatcctt ttttttgagg gagataaaag agataagctt tttctagtga cctctggtta
    49501 tttcaaggtg gagcagtccg atcaatcagg aaccttcacg tatacggatt tcatcagaca
    49561 cggcaccatt tttccttacg gtggcctctt tacagatgat tattaccatt tttcagtggt
    49621 agccatgaca gacgtgactt atttttactt tccagtcgat ttatttgaag attattcgct
    49681 tgaaaatcgt ctacaaatga aacacttata tagtaagatg tctaagctgc tcgagttaca
    49741 tgagttgagg gtccgaaact tgattacatc aagtgctagt tctcgtgtga ttcaatctct
    49801 ggcgattttg ctggttgaaa tgggtaaaga cagtgatacc ttaccttttc aattaacaac
    49861 aacagatatt gctcaaataa gtgggacgac aagagaaaca gttagccatg tgcttagaga
    49921 tttgaagaag caagaattga ttaccataaa aggtaagtat ttgacttatc tagat
//
LOCUS       DAUGSW010000012        43816 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUGSW010000012 DAUGSW010000000
VERSION     DAUGSW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43816
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.012"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..270)
                     /locus_tag="VIB18_000760"
     CDS             complement(<1..270)
                     /locus_tag="VIB18_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8765784.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMR"
     gene            complement(339..410)
                     /gene="shp3"
                     /locus_tag="VIB18_000761"
     CDS             complement(339..410)
                     /gene="shp3"
                     /locus_tag="VIB18_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEQ8765785.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            490..1341
                     /gene="rgg3"
                     /locus_tag="VIB18_000762"
     CDS             490..1341
                     /gene="rgg3"
                     /locus_tag="VIB18_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEQ8765786.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKCQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1594..5133)
                     /gene="smc"
                     /locus_tag="VIB18_000763"
     CDS             complement(1594..5133)
                     /gene="smc"
                     /locus_tag="VIB18_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEQ8765787.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LFQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGTNRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5134..5826)
                     /locus_tag="VIB18_000764"
     CDS             complement(5134..5826)
                     /locus_tag="VIB18_000764"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEQ8765788.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6269..7078)
                     /locus_tag="VIB18_000765"
     CDS             complement(6269..7078)
                     /locus_tag="VIB18_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8765789.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVSQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(7082..8434)
                     /gene="vicK"
                     /locus_tag="VIB18_000766"
     CDS             complement(7082..8434)
                     /gene="vicK"
                     /locus_tag="VIB18_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEQ8765790.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWIEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8427..9137)
                     /locus_tag="VIB18_000767"
     CDS             complement(8427..9137)
                     /locus_tag="VIB18_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8765791.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9299..10333)
                     /locus_tag="VIB18_000768"
     CDS             complement(9299..10333)
                     /locus_tag="VIB18_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8765792.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFLAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10389..11636)
                     /locus_tag="VIB18_000769"
     CDS             complement(10389..11636)
                     /locus_tag="VIB18_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ8765793.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDHTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLEKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKMFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLRDNGKINREVLLNKIPKQWLS"
     gene            complement(11593..12741)
                     /locus_tag="VIB18_000770"
     CDS             complement(11593..12741)
                     /locus_tag="VIB18_000770"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEQ8765794.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNAVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGPYKVAQFSPDTNSPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASRCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGEG
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVVKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGHYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13136..13285)
                     /locus_tag="VIB18_000771"
     CDS             complement(13136..13285)
                     /locus_tag="VIB18_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEQ8765795.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(13486..14271)
                     /locus_tag="VIB18_000772"
     CDS             complement(13486..14271)
                     /locus_tag="VIB18_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765796.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESAGS"
     gene            complement(14273..15091)
                     /locus_tag="VIB18_000773"
     CDS             complement(14273..15091)
                     /locus_tag="VIB18_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEQ8765797.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLVVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLMMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(15093..16085)
                     /locus_tag="VIB18_000774"
     CDS             complement(15093..16085)
                     /locus_tag="VIB18_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8765798.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQTFGKMKSLSFELEAGQEEVVSQFLGLPDIT
                     VERHELTLEIQYDSSRYQTADIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(16226..18169)
                     /gene="thrS"
                     /locus_tag="VIB18_000775"
     CDS             complement(16226..18169)
                     /gene="thrS"
                     /locus_tag="VIB18_000775"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEQ8765799.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSCPDAQA"
     gene            complement(18591..19925)
                     /locus_tag="VIB18_000776"
     CDS             complement(18591..19925)
                     /locus_tag="VIB18_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8765800.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19927..20925)
                     /locus_tag="VIB18_000777"
     CDS             complement(19927..20925)
                     /locus_tag="VIB18_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8765801.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKED
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(21056..22057)
                     /gene="ccpA"
                     /locus_tag="VIB18_000778"
     CDS             complement(21056..22057)
                     /gene="ccpA"
                     /locus_tag="VIB18_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEQ8765802.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22231..23316
                     /locus_tag="VIB18_000779"
     CDS             22231..23316
                     /locus_tag="VIB18_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8765803.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYYDLAPVLFVPALEVAKASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLIKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23365..24030
                     /locus_tag="VIB18_000780"
     CDS             23365..24030
                     /locus_tag="VIB18_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8765804.1"
                     /translation="MDQTIHHQLQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            24041..24418
                     /locus_tag="VIB18_000781"
     CDS             24041..24418
                     /locus_tag="VIB18_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8765805.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24563..25489
                     /locus_tag="VIB18_000782"
     CDS             24563..25489
                     /locus_tag="VIB18_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8765806.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPVMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25700..26383
                     /locus_tag="VIB18_000783"
     CDS             25700..26383
                     /locus_tag="VIB18_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEQ8765807.1"
                     /translation="MEWIKLIGIVIIVLGFILKCDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQSLTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26383..27309
                     /locus_tag="VIB18_000784"
     CDS             26383..27309
                     /locus_tag="VIB18_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEQ8765808.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27359..28006
                     /gene="pcp"
                     /locus_tag="VIB18_000785"
     CDS             27359..28006
                     /gene="pcp"
                     /locus_tag="VIB18_000785"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEQ8765809.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERIAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28124..28843)
                     /locus_tag="VIB18_000786"
     CDS             complement(28124..28843)
                     /locus_tag="VIB18_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEQ8765810.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKAICNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFTLLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28849..29316)
                     /gene="smpB"
                     /locus_tag="VIB18_000787"
     CDS             complement(28849..29316)
                     /gene="smpB"
                     /locus_tag="VIB18_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEQ8765811.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29319..31652)
                     /gene="rnr"
                     /locus_tag="VIB18_000788"
     CDS             complement(29319..31652)
                     /gene="rnr"
                     /locus_tag="VIB18_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEQ8765812.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSSLDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINPQGYVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILETMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKVEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMIREYNQPSQEKRDHFAQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVSSVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGIK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31746..31982)
                     /gene="secG"
                     /locus_tag="VIB18_000789"
     CDS             complement(31746..31982)
                     /gene="secG"
                     /locus_tag="VIB18_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEQ8765813.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(32028..32174)
                     /gene="rpmG"
                     /locus_tag="VIB18_000790"
     CDS             complement(32028..32174)
                     /gene="rpmG"
                     /locus_tag="VIB18_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8765814.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32171..33364)
                     /locus_tag="VIB18_000791"
     CDS             complement(32171..33364)
                     /locus_tag="VIB18_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEQ8765815.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPVRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMLTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33486..34988)
                     /locus_tag="VIB18_000792"
     CDS             complement(33486..34988)
                     /locus_tag="VIB18_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEQ8765816.1"
                     /translation="MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISELGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNEKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFAGKYTQSIDRDSAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKE
                     QAAAEKTSRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35178..35771)
                     /locus_tag="VIB18_000793"
     CDS             complement(35178..35771)
                     /locus_tag="VIB18_000793"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEQ8765817.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLSLANPR"
     gene            complement(35768..36595)
                     /gene="mutM"
                     /locus_tag="VIB18_000794"
     CDS             complement(35768..36595)
                     /gene="mutM"
                     /locus_tag="VIB18_000794"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEQ8765818.1"
                     /translation="MRELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDCLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(36767..37633)
                     /gene="rgg2"
                     /locus_tag="VIB18_000795"
     CDS             complement(36767..37633)
                     /gene="rgg2"
                     /locus_tag="VIB18_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEQ8765819.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEISGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37722..37790
                     /gene="shp2"
                     /locus_tag="VIB18_000796"
     CDS             37722..37790
                     /gene="shp2"
                     /locus_tag="VIB18_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEQ8765820.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38589..38858
                     /gene="stcA"
                     /locus_tag="VIB18_000797"
     CDS             38589..38858
                     /gene="stcA"
                     /locus_tag="VIB18_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEQ8765821.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39178..39576)
                     /locus_tag="VIB18_000798"
     CDS             complement(39178..39576)
                     /locus_tag="VIB18_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEQ8765822.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     gene            complement(39669..40739)
                     /locus_tag="VIB18_000799"
     CDS             complement(39669..40739)
                     /locus_tag="VIB18_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765823.1"
                     /translation="MMMLKDVNVGMSRLLVRGAIALVVGIGFSVATDSVSASSRGFGI
                     GYREEKTQMFSSDQPYQVVLYRDEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGAFPDNIK
                     VSINSKGGQATITYGDGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNQDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
     gene            complement(40957..41085)
                     /locus_tag="VIB18_000800"
     CDS             complement(40957..41085)
                     /locus_tag="VIB18_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAAX amino terminal protease"
                     /protein_id="HEQ8765824.1"
                     /translation="MGLIFASLYHYTKSIYYSIGVHIVWNSLPYIFYFLVFLLDLF"
     gene            complement(41134..41480)
                     /locus_tag="VIB18_000801"
                     /pseudo
     CDS             complement(41134..41480)
                     /locus_tag="VIB18_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973012.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(41727..42137)
                     /locus_tag="VIB18_000802"
     CDS             complement(41727..42137)
                     /locus_tag="VIB18_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765825.1"
                     /translation="MRNILRFLGIIIISAVILFSIGSFYDLPLMKNIQLICWSFILDL
                     FVFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIVFIIIIGCLTSISEVSIYFYL
                     HLIVVCYTIGMILSLGRLISPNHSIFNKLKKRNE"
     gene            complement(42331..42612)
                     /locus_tag="VIB18_000803"
     CDS             complement(42331..42612)
                     /locus_tag="VIB18_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765826.1"
                     /translation="MKTLDIIFNLSDRKMIFLENVEKLGGYIVPFTLIILSVAYNFRH
                     PYPIWAAVLGGISLIVIFIYFILIVYLYLRYRYLVWKKIPEIKINSTEL"
     gene            complement(42662..42856)
                     /locus_tag="VIB18_000804"
     CDS             complement(42662..42856)
                     /locus_tag="VIB18_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ8765827.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIP
                     WQGYILCGAAGAATNIIWPH"
     gene            complement(43150..43350)
                     /locus_tag="VIB18_000805"
     CDS             complement(43150..43350)
                     /locus_tag="VIB18_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8765828.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            complement(43363..43590)
                     /locus_tag="VIB18_000806"
     CDS             complement(43363..43590)
                     /locus_tag="VIB18_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ8765829.1"
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
BASE COUNT        13372 a         9257 c         7555 g        13632 t
ORIGIN      
        1 cctcattacc tctcttttat aaggtaaagt tatatttaat ccaatacatt ttggatcatt
       61 tatcagatgt ttgattttat cttctaaaca cactgagtct accaaaattt ttttatgttt
      121 atattcatcc agaactccta tgttgtgatt tagatattca aataattcat ctgatataga
      181 atgttcaact ggattaccaa gcaatgcaga atacataaat ttcatcctcc tacgtttaat
      241 tagtttacta ctaacataaa gtacaagcat tacacagagc taaccattac ctataagtct
      301 ttagatactc taaagactta agtgtacacc taagtaactt acccaccaac aataatgata
      361 atatccattg ctaaaattaa aatcggcaaa aattttgaaa ttttcttcat aagcggactt
      421 cctttcagtt tttatttatt gtacaataaa aaaaaacaga attgattttt gttgggaaag
      481 tgggaaaata tgaaatcaaa acttggtgcc acacttagaa aagttcgaaa aggaaagcaa
      541 attagtctgt gcttcgtggc agatgaacac ctttcaaaat cacaaatctc tcgttttgag
      601 cgcggggagt cagagatatc gtgtatccga ctgatcaata ttctagacaa attacacatt
      661 actttggatg agtttcttat tttacatgat gaagactata ccaattccga aacatttgct
      721 aacctggtac agtatattcg taagcaatat tcatcacaaa atatcaataa tatagcatgt
      781 ttactttccg acacttctga ttacactctg aattcttttg agaaaacaat ggtaaagtcc
      841 attttacaca caatggattc aagcatcatt ccatcagatg atgaattact tcaactaaca
      901 gattatctct ttaaagttga aaaatggggc tactatgaaa tccttttgtt gggtaactgt
      961 gtacgaacaa ttaactacaa ctcctacttc ctattgacaa aggagatgtt aaataattac
     1021 atttactctt cacggaacaa aactaataaa cgaattgtca ctcagcttgc tataaattgt
     1081 ttcattctta gtatcaataa ggaggaattt tctaattgct cctatttaat tgatgagata
     1141 aaaaccttgt tagataatga attaaacttc tatgaacaga cagtttttct ctatgcaaca
     1201 ggttactttg aatttaagtg ccaattagaa actggagttg aaaagatgaa acaagccata
     1261 caagttcttg atattttaaa tgaagacaag ttaaaattac attacgctga ccattttgat
     1321 aaactagtca acaaagatta agtaaaatca ttctttacct tttaacgaaa cgccaatcaa
     1381 gggtgtctca ataaaaaatc atctactctg acaacttttc tcttttacct atcgacagct
     1441 aaaaagcctt ggaaactgct atttccaagg ctttctttgt actctattgt atcaattagc
     1501 ttattccgat ttctgttgct attagtttaa tcatgaaatc tcctaactta tggccgaaca
     1561 tccaaaaaaa cagaaggaac tcccttctgt tttttaattg gtcatctctt gagcttcttt
     1621 taattttaca gatacaattt tagagacccc cgattcctgc atggtaattc cataaatact
     1681 atctgctgca gccattgttc ctttacgatg ggtcacgaca ataaattgac tatctttgtc
     1741 aaagcgattg aggaaatccc caaagcgctt aacatttgct tcatcaagag ccgcttctac
     1801 ctcatctaaa atcacaaacg gaatcgtttt aacacgtata atagcaaaca ataaagccag
     1861 tgctgacaaa gctttttctc cgcctgacat caagttaaga gattgaattt tcttaccagg
     1921 aggctgcaca gaaatctcta taccagcaga caagaggtct gtttccgtta aaaccaaatc
     1981 agcagaaccc ccaccaaaca tctgagtaaa ggtttcttta aaactttttt gaattgcctc
     2041 aaaagtcact ttgaaacgag ccttcacttc gctatccata ctattaatag tctctagcaa
     2101 aagattttta gcttttgtca gatctgtctt ttgacttgtt aaaaaagtca aacgctcatg
     2161 cacttcctca tactgattaa tagcatcact attaattggt cctagtgcac gaatagtctt
     2221 ttgtaaatgg tgtaattttt ctttggcact ttctaagtga tcaatactat ttgttacctc
     2281 ctttgcgtct gctagtgtca tttgaaaatc ttctgataaa cttttagcat aggctcgtaa
     2341 gcgattagcc acttgctcta aatgtgtctc taacttggtt tgacgacgaa taaatgtgtc
     2401 atttttttcg ctttctttgg ttattttttc tgctgtttct tctaagcggg cctcatagtc
     2461 ctctatttca aatcttaatt ggactaaacg tttttgagca ccagacttat gctctgtggc
     2521 atcttgtaac tgtttttgcc actggggtag tctttgaatg ctgtcttgac ttacgttatt
     2581 gtttagtatg ctttcaagtt tgagaatatt ttgctggcat tgcttcagct gagttcttag
     2641 acgagattga ttagcttgct caaatttctt ttcattaagt aaatctcttt cttgtaaacg
     2701 agcttgagat aaagcttggt gaatgttttg tgttttttgc ctaatcaaat ctttgttttc
     2761 tttgatatca tcaatatcac aagttaaggc attttttttc ttagcaatag ctgttaatgc
     2821 ttcttcaata cgagcttgtt ctgccaataa agattcatca gaatgagtcg tctgactttg
     2881 atcaagggca gctaacaaag cctttgaatc ttcttgtttt tcttgcaatt gctgataagc
     2941 catttgagct ctttgttcag ctaagcgtgc ctggtcaccg gctaatttca attgtgtcag
     3001 ttcttctttt tttgctatca aatcgctttg caaggcagct acttcttttt cagttatttt
     3061 taattgctca actaatcgcg ttaattcctc actgatttgt tctaactctg gtttgataaa
     3121 agttgtattg ctttgtctat tagttcctcc tgaaaaagaa ccacctggtc gtaattctgt
     3181 tccatcaaga gtaacaattc ttaccttata tcctaataag cgcgctgcaa tattagcttg
     3241 atcaatagtt tcaaagatag cagtactaga taaaaggttt tggataatag ctgaaagact
     3301 atcatcatag cgaaccaatg attctgcagt tcccagataa ccttcacaag tcgctaattg
     3361 acgatgatag tgttctgaca atgatctagc ctttatagta gttaaaggta aaaaagttgc
     3421 tcgtccttgg cgattttttt tcaaataagc aattgctctt tttgctgcag cttcgtctgt
     3481 tacaataata tgctgactat tagcacctaa tgcaatttca agagctgttt ggtaatcaga
     3541 atcaaaagaa aggtgttcac tgactgcacc tatgatccct ccaagctttt tttgtgattg
     3601 aaggacagct cgtactcccg catagaattg actatgactt ttttgaatag attctaagct
     3661 agccttacga gcttcttttc cttttttttg atccaacaag tcaaatagtc tttcttgatt
     3721 cagttggtaa tctctttcta attcctgaac gcgtttatca ccttcttgat aattttggaa
     3781 caacatttcg acttgctctt tttgagcttt ataatgagct tgagcttttt gagactcgtc
     3841 attaagttga tcaagcttag taacaagtag ctgatattct tgagccttat gttgacgagc
     3901 ctgtttttct ttgtctaaat gggcttttaa agctgtcagc tgatttgata aggccgcctc
     3961 tttttgcatc aataatacaa actcttctct tagagtttcc attaattggt cgggatcact
     4021 tgaaaaacgc tctaatgcat tgctcaattc gtttaactgt tgtttgacat cacaaagttg
     4081 ttgatcaata tgcaataatt gttctgtacg ctgcttttct tctgcttgaa aaccatccaa
     4141 ttgttcttgt aactgttcga ggtgtttttt ggcttctgcc tttttctctg cttcttggcc
     4201 actttctagc ttaaccaatt caatttgctt ttccaagtca gctattagct tggttaattc
     4261 taataatgtt gtttgggttt gatctgactc ttgactaaga acctgctttt tttgcttgaa
     4321 tttttggtaa tcttcttcca tagattgacg cttagcgtaa taagatgcta agtcttgttg
     4381 taaagcagct aaagcttcag tatctttagt ctgtctttct tgagctatat caatatcttt
     4441 gactagaata tctagttgta gttgcttacg attggcatca agttctaaaa attgtttagc
     4501 tactttagct tgcttttcaa gtggggccaa ctgcgtgtct agctcataaa taatatcctc
     4561 tagacggtct aaattatctt gagtttgatt taatttaatc tgagtttctt ttttacgtgt
     4621 tttatatttt aaaacaccag ctgcttcttc aaaaatggcg cgcctttctt caggtttact
     4681 attgaaaatt tcctctacac gaccttgaga aataatggag aaagaatcac gaccaagccc
     4741 tgtatccata aacaaatcat gaatatcacg gagccttacc ttgcgaccat caatcagata
     4801 gtcactatct ccatttcggt aaatatgcct ttcgacacgg atttctttct tggcagtttt
     4861 tataaaatga tcggaattat caagaacaac cgctacctta gcatagttta gaggattacg
     4921 gttttgtgtc ccagcaaaaa tgacatctgg catcttgccc ccacgcagat ttttagcact
     4981 tgattctcct aaagcccaac gtaaactttc tgtaatatta cttttacctg aaccatttgg
     5041 tcctacgact gcagttactc ccttatcaaa ttcaatttta gtcttgtccg caaaggactt
     5101 gaacccttcc aactcaattt cttttaaaaa catctaaacc tcactaagtt gggcaagggc
     5161 atttttagca gcatcttgct ccgctaattt tttagactta cctaaacctt tactaaggac
     5221 agcaccatta acaactatcg atacctcaaa ttgtttagcg tgggcaggtc ctttctcact
     5281 aatgacttga taatcaatag ccacatcacc ttttgtttgc aaaaactctt gaagacaagt
     5341 tttatagtct ttaacccttt caaaattccc tttttccacc tgaggaatca tgacttgttt
     5401 caagaagcga cgtactgcat caatcccctt atctaataaa agagcaccta aaaaggcttc
     5461 aaataagtct cctaaaatag tatcacgacg gcgaccacct gacttttcct caccttttcc
     5521 tagtttgata taagcgtcaa aagaacaaaa tcgtgaaaaa cctgccaagc tttcctcacg
     5581 tacaatcatg gaacgtaact tagacatatc tccttctgtc tttttaggat actttgcaaa
     5641 taaatactct gaaataatca attgtagaac agcgtctcct aaaaattcca agcgttcatt
     5701 atgtgaaacg tttaggagac gatgctcgtt agcgtaagag gtgtgggtaa aagctgtttc
     5761 tagtaaagtc aaatcattaa attgaatatc aaaagatgtt gagagtaact cttcaagctg
     5821 tttcataaaa aatccctttc atatttgtca gtagacctta tttagtatac caaaaatcca
     5881 cctagaaaac cgactctaag tggatttttc gtgatttatt aaacatctta aatacccgtc
     5941 aaaggaaact ttctcataca atcaaaagac tctacactat ctgaggggaa tttcccacta
     6001 cagtcccact acagatagta tagagctatt ttgtttttag tctgaacaac taaaaaacta
     6061 cctcatcttt ataatcctca acacctttga taaatagatc agacaagcca aaactacagg
     6121 ctaatttaag tctattgatg ctctaaagga tgaccaatga gagttcattg aactcagaag
     6181 acaatacgct ttaagacatc aaaaaatagc cctgactggt atatcaccaa tcagcgctac
     6241 tttgcatatt ctcttttagt ttcttatctc aaatatcagt taatggacaa gcagtatctg
     6301 gagaggtatc atggaccgta aagtctgtac ctacggctaa atctgccata gccagttgac
     6361 tgaccatcgt catatgcgct aactctttga tgttattttc tttactcaga tgacctaggt
     6421 atattttttt ggtattgtac cccaggcttc taatcatggc tcccgctcca tcttcatttg
     6481 ataaatgtcc taaatcagat aaaatacgct gcttcaagct ccaaggataa gagcctgatc
     6541 tcaaaatttc aatatcatga ttggattcaa tcaagtagcc atctgcattt tcaataatac
     6601 ctgtcatcct atcactgaca tatcctgtat ctgtcaacat cacaaaagac ttattatctt
     6661 tcataatccg ataaaattga ggatcaatag cgtcatggct gactccaaaa ctttcgatat
     6721 caacatctcc aaaggtcaaa actttatccc tttggaaaat atgtttttgt gaggcatcaa
     6781 gcttacctag catattgcac tcatccatca gctgccatgt tttttcatta gcatagatat
     6841 ccaaatggta tttgcgggcc ataacgccta cacccttaat atggtcagag tgctcatggg
     6901 taatcaaaat agcatccaaa tcctcaggtt tgcggtcaat ttcagcaaga agactggtaa
     6961 ttttcttacc agtaagccct gcatcaatca ataagcgttt tttaggtgtt tctaaataaa
     7021 aacaatttcc tgtggaccca gatgctaaaa tactatattt aaaaccactc tcattcattg
     7081 attagtctac atcttcctcc cattcttcat agatggctgc atctttttca taaggcaaga
     7141 caatagtaaa ggtcgatcct ttaccatagt cactcttagc ccagataaag ccatggtgct
     7201 gcttgatgat ttctttagca atggcaaggc ctagaccggt ccctccttgg gcacgacttc
     7261 ttgccttgtc tacacgatag aaccgatcaa aaataagagg caaatctgtt ttagggatac
     7321 ctagtccttg gtctgaaatg gaaataatta attgggtatc tgttgttttc atacggactg
     7381 taatttttcc accatctgga gaatacttaa tggcattgtt caaaatattc tcgataacct
     7441 gtgtcatttt atcattatca atttcaatcc agacagaggt aatagggtaa tctcttacaa
     7501 tttcatagac ttttcctgta cctgtatgct gatttttaac caaatcaaat ctgtttaaaa
     7561 tagaagttat aaaagcagta aaattagtca tctctactgc taattgggtt acttgattat
     7621 caatccgaga caggtttaaa agatctgaaa tcatacgcat catccgatta gtttcatcaa
     7681 gagaaacttt tatgaaactt ggagcaatat cttctttaag tgcaccttca tcaagagcct
     7741 ccaagtagga tttaaccgaa gttaaagggg tccttaattc atgacttaca ttagagacaa
     7801 aaagacggcg ttcacgttct tctttttctt gttctgtggt gtcatggagc accacaacca
     7861 atcccgaaat aaaaccactc tctctcctat tcaacgcaaa gcgcaagcgt aatgagacaa
     7921 actcacccat atcatttcgg ctattaacag ttaccactgg tgttttggat accaaatcac
     7981 ggtaagtata tgaagtatca ccttctaaca aatctgtaat gtttttcttt agtgcctctt
     8041 ctttacttaa atttaattgc ttgcgagctg tctcgttaat catgatgatt ttaccagacc
     8101 ggtctgtagc aagtacacca tctgacatat aagccaaaat acttgccaag cgattttttt
     8161 cttgggcaag attttcatgc gtcaagcgaa aaacatctga caggtcattt aactggtctg
     8221 aaagctccat taactcaatg tctgcttttt cgtcgattat atcagtatag cgaccattaa
     8281 tcaagtctcg gattttatgg ctcatcatcc gaataatacg tgcatttcgg taatcacgca
     8341 ccgcaagatg gataaagtaa aaagcaacaa aaacaagtaa gataaggatc gctaattcaa
     8401 atgtggataa gtttccaatg atatctctag tcataagatt tcatgtagta cccaacacca
     8461 cgtcttgtta aaatatactc aggacgactt ggtgtgtctt caattttttc acgaagacga
     8521 cgaacagtca catcaaccgt gcgcacatcg ccaaaataat catatcccca aacaatttcc
     8581 aataagtgtt ctcgtgtcat cacctgaccc atatggttag ctagatgatg caatagttca
     8641 aattcacgat gggtcaactc tacctcttga ccatgttttt tagcaacaaa cgcatctggt
     8701 aaaatctgta aattaccaat ggttagttcc tgtgtacctg aagaagcatt ttcttctgca
     8761 acagccgttt caatagtttc ggtacgacgc agatgagcct tgacacgcgc cagcaattcc
     8821 cgattagaaa aaggcttggt cacgtaatca tcagccccaa tttcaagtcc aataaccttg
     8881 tcaaactcac tatctttagc cgacaacata ataatcggga catgactggt tttacgaatt
     8941 tccttggcta cttcaagacc gtccaactca gggagcatca aatcaagaat aattaaatct
     9001 ggcttttctt cttcaaaaat tgttaccgct tcgcgtccat caaaagctgt aacaatgtca
     9061 taaccttctt ttgtcaaatt aaacttaata atgtcagaaa tcggtttttc atcatccaca
     9121 ataagtattt ttttcatgtc tatacctcag aaagttcttg taattgatat tacaatttgt
     9181 gatttttgtg gttagtaaaa aatcacaaaa ctatattttt ctaaattatt tctacctgat
     9241 tataccaaaa attcagccta attgacaatg acgactaccg ttacaaatag agtactttct
     9301 aaaaccaacc ctttatagga tgaatttggc gtttgaattg cttagcagat tttttgactc
     9361 tggcaaaact actcttgttg tggtaagcaa aaagtccttt ggcattaaaa taagagaaca
     9421 taaagtcatc tttttgagct ctaaaccact ggcgaaatac tctttttggc gatcgaaatc
     9481 ctttaagggt gtctcttcta aactgaggat cgtgacggct aatcggatca acatctaaat
     9541 cccaatgtct aggaccatct gtgccatagt taaaagatgc accattgaca attccttttt
     9601 cggtcactac ttctgcatca acttcattaa gaaaaaagcc tgtgctatct agaataaatt
     9661 cggtatgaaa ccaaagaagt acttttatat tataggaaac ttcttgactt ggaaaaatga
     9721 ctttattatc ttcaaatctt agtttattat gtaacctggc agaatccatc aaggtataat
     9781 ctggtgcttg ccgccacaaa caaggccctt ttttagacct caaaaaaagg gccagagctt
     9841 gggcgtctgt catctcaatc attttataat ggtttctgat agattgagct tgttgactag
     9901 agatgacata acgaaattga tgcaaacgct tttcaagctc acctgcttgg cttagtgttt
     9961 tgccaggaaa agcttgatca actaagctag ccaactcttt ccaaaacata tgatctggca
    10021 atagagatgg atggaatcgg gtgagtagcg tttgagtttc atgcaactga ccacttagct
    10081 caaatggcat ctctaccaaa tcaagaagaa acgttagtaa ctgcttagct gattggtttt
    10141 ctttttcaat aggccatatt acccagaaag ttggagaacc aagtcgatta tcaatgatag
    10201 gctctttagc tatagcaaga aatgcttggt ttgataaacc tgcgttttga tagcatttca
    10261 aggcctgata gcgatctaag atagcttgtt tcatggcctt ctcctcatct tttttgacca
    10321 tattataaca catctaaagc tgaatcgtca cttgtatctc actataagca aaacgaaacc
    10381 tgaagtcgtt aactaagcca ctgtttgggt attttattta aaagaacttc tcgattaatt
    10441 ttaccattat ctcttaaagg caaacaatca atcacaagat agtacttggg aagttgtcca
    10501 gagtttaaat aaagagctaa aaagtcttta ataggtgcta ggcaatcctt cttagtcaaa
    10561 actaatacta atattagggt ttcgttttct ccttttccta tctttaaagc gtgcgcttct
    10621 ttgacgtttg gcgcttggtg agcgagttca actaggctag gcaggtggca tttcactcct
    10681 cgttgattaa cccagtcatc ttgtcgccct tctaaaatta aacccgctgg gctcattttt
    10741 cctaagtctg agacactgta tggttgtgac attccttcta cactataagg agtctctaca
    10801 aaaatttcct tatctttgaa actgatagac acatcaggaa agggctgtcc taccaaacca
    10861 ttaattttga cagcagctct gccattacac cacgttataa aagataattc actagccccg
    10921 tagaaaatga caatttcaag ctgaggaaat tttttgtaat aatgtcttag taattcttgt
    10981 gatatcattt gcgaagaggt caataagtga gtcgcagtca tgttgttctt agtcaaataa
    11041 ggtagcaagc gatttaggta ggtcggtaaa aggtaaaggt gactcacctt ttttgcttgc
    11101 cataagctta accacgtttt caaagacagc ttttggctta aaaccagaca tcccccggcc
    11161 catagttgag ctaatgctaa gttaagattg ccagtaaaac taaaactacc atgtaagaat
    11221 agacaactat taccagtcat accaaacatc ttattttgat aatcaaaaag tctcgtccaa
    11281 gttgatagac aacgccaaaa taattttgct ttgccagtcg ttcccgaact caaaacagca
    11341 aaatcagctt tttcaagaag ctcaccatcg acgtgtttta tttgctgctg aaatgtacct
    11401 gagatattag ggtgtaaaat gataggacag ctgccttctt ttaatcctcg taaaaaagag
    11461 agtaactgat taagatagcg actatgactg atgatatatg gtacactgtc ttttattgta
    11521 tgatccttta ttaaaaccgc ttgccatagc tcttgataag tcaagcttat ctgatcggct
    11581 acgatagctt ttttatttgg gcattgcttt gcccaatatt ctagctttgt cagcatgact
    11641 aaactcctta tgatatttta gtaaaacagc aaacccttgg ccaccagctg ctgctatagc
    11701 agctattcca tagtgtccat ttttaatctc taaagccctc attaagtgca atattataat
    11761 ggctgctgag gcaccatagg gatgaccata agctaatgca ccaccaaata tattatagcg
    11821 gtccaataaa tctgggtaat gggtttcaaa taaaccatca ataacggcaa aagcttcgtt
    11881 ccattcaatc gctgtcatat ctgccatccc tagaccatgt ttttccaaaa ggacttgact
    11941 agccttaacc accattaaag ggctacgctg tgggtctcct gctacttcta ccacatcaat
    12001 cagtttaaaa gctgaaggct gactacttag ctgtaaaaag gcagcagcat catgggtgag
    12061 gcaggcattg gctgcactaa tcacgtgacc ctctcctaag atagggggta cctttgacaa
    12121 caccttactt gacaagcgcg gtcgaatacc ttgatcactg gcccctggca ggtctagaat
    12181 aagatcagct aacagggctt gctcctggca acgactagcc ttttgatgac ttctcaatgt
    12241 ccagtgattc aaatactcct tagtaaagcc atgttctctt gccactcgtt ctgccccctc
    12301 aatcatcgca aatggactgt tggtgtccgg agaaaactgg gcaactttgt aaggaccttg
    12361 gcgccaatca gctgaagcat ataccgattc aggttgtaag gagctgcttt caatccctcc
    12421 cactaaaagg ttgcttgcca tacctgcctt gattttagca taacccacgg aaagagctgc
    12481 accagctgat gcacactgca tatcaaccgt caaagcagag acagattctc ctaaatgaga
    12541 atacagggtc atcaagcgcc caatattacc acccgttccg acggcattgc cacaaatcac
    12601 ttggtcaatg ggaactggat acttattttg taaagcattg atgagctttg ctccaaggat
    12661 ttctggttgt tctttagcaa attgtttccc tactaaaccg ataggggttc taaggcctgc
    12721 agcaatataa acatccgtca ttatattgac ctcctttatt ttcgatgtcc ttaaatggtt
    12781 attatataat tatttctgat ggttttcttt tttgaactaa taactgctaa aaatacacct
    12841 aaattaattt agagaatctc tttagtctcg ctagtgtgcc atcaataaaa tctataaaat
    12901 tctctaacgt cattgaaatg tcaagtccca caactattgt cgtagaagtc acttactttg
    12961 ttgctttaac attcaaactg taacctttgt ttttgataca gggtgacttt attatactgg
    13021 aaaaccattc ctaagaaaag aaaatcttat atagaataaa gaattagaca ccataaaaaa
    13081 gctaagctgt gacacttaac ttttttatgg tattgacaaa ccttgtcttt actatttatt
    13141 gatagttaat gcctctaact aaaataaaag ccatgtctgt atcagcctgc aaggcatctg
    13201 ctaagctggt atcgttacta gatttgacag gtctcataaa ggcaaaagat ctcaaagttc
    13261 cataaacgtt atctagcaat tgcatgcaac cacttgaaat atatctgctt atgttatttt
    13321 accgccctta atttagacca atctgctgat gatggttcca aacaatgcct acgcttggta
    13381 aaccatcaca aaaaaaggca gccgttttta caacagctgc cttccttcat tatctaggtt
    13441 ttcatattct gacctaaacg attttcaatt tgtttaagag tctctctagg aacctgcact
    13501 ttcataagca tccaggcccc atttccaaag cttaagcgac aaggccaaaa ccagtaacga
    13561 caccactacc aagcctccaa tattaaagag caggtgttga cctgttaaaa aataagaagc
    13621 agggtaataa gctgtaaaag caaagggaat gataaaactg attaaccacc gcaaaaagga
    13681 atggtaaatg gacatagggt acttagaaaa gtcattgaac atgtaaaaaa tatagataac
    13741 tgccccagac tgcttggtcc aaaaagaaat gctggcggtc gcaattttta aagaggtgta
    13801 aatcaaggtc gcaaaaggaa taaccaaaat aaacaaaagc accttaggaa gagtccatac
    13861 gatactacca gccgtggtca ctaataagat aaccccaacc aataattcac ccagggcatc
    13921 cacttgaaag gtctcaacta aaacatgaaa caaaggacta attggtctgg tgaggtactt
    13981 gtcaaattct cctttgcgga caagccgttg ccctaaagcc caaagattgt caaaaaagag
    14041 gtgatcaatt ccctttggaa tcaaagaaaa gccataaata aaggcaattt gttcaaacgt
    14101 ccagccttct aaagaaggga tatgttggaa aagtaccgat aaaaagagca gattaagacc
    14161 ctgagtgaga aaaacaccta gcactcccac cacaaaatca accttgtatt ccataatttg
    14221 tttgaggtat tgtttgataa aaatagcgtg catacgtctc aattttgcca tctcaccctc
    14281 cttgaatcgt taaatggtac tgaacctttt tccagatgac ttgcgataag actaccatca
    14341 tcagtaacca aaagatttgc aaacttaggg ccaccattat ctgactaagg ctgtatttcc
    14401 caatgacaat cataactggc gtgtaaacca aagaggaaaa cggtagaaaa ctaagcacta
    14461 tagaaaccat tttaggaaaa aaagccaatg gaatcaaact gcctgacata aaggcaacca
    14521 aggcattttt caataaatta gacccccaaa ggtttttaaa aacaaatgct gaaaagccaa
    14581 aacaaatgtt gaaataaaaa ttgattaaaa aagctaataa aaggctaact aaatacagac
    14641 aactgctggc taggacttgc aagatagaca gccccgccat gactttaata ccagataaga
    14701 ccactaaaaa aggaaagccg acactcatta gcacaatcca gcgaaaacca atttccataa
    14761 agaggtaaga ggctgcaaaa tgaactggtc gaagcaggcg catgatgata gaaccatctt
    14821 tcacttcttc gccaatcata aaggagctgt ctgatttggt cagtaaagtg gtcacaaaac
    14881 tcatgataat gtaaaaggtc atgtcagaca gagtaaaacc attgattaag gattgcttag
    14941 acgaatcaaa aacagccttc cagaggtaat aagctacaaa agcccccatg acatctccaa
    15001 tacgatacaa aaagaaatta acgcgatagg ttattaattc ctgaattcct gcactgagaa
    15061 agggtctata acgtttccaa aatgaccaca tcttaaagct cctttcggta gaaacgacga
    15121 acaatatcct caatatctac atcagtcatc ttcaaatccc tgaccgcaaa atcagccatg
    15181 gttttttgaa taatgtccgc tgtttgatag cgcgaactgt catattgaat ttccaaagtt
    15241 aattcgtgtc gttccacagt tatatcaggc aaaccaagaa actgagaaac aacttcttcc
    15301 tgtcccgctt ccaattcaaa agataagctt ttcatcttcc caaatgtttg tttgagttgg
    15361 gtcaccgtgc catcaaagat ttcttggccc ttatcaatca tgataatccg atcacagagc
    15421 tgttcaatat cactcaaatc atgggtcgtc agtaaaatag ttgtctcttc ttcttgatta
    15481 atttgagtaa tggcacgccg aatgttgtcc ttcacagaaa catcaagtcc aatcgttggt
    15541 tcatctaaaa acaatacttt aggattatgc aacaaggaag cagcaatatc agctcgcatc
    15601 cgctgaccga gtgataaggt ccggacagga tccttaataa actcattcag gtccaaaacc
    15661 tcatttaaaa aatccatgcg cttgcgaaag gctttttcag gcacatcgta aatttctttt
    15721 aacacgacat aggtctcttg caaggccaaa tcccaccata gttgtgttcg ttgaccaaaa
    15781 acagctccaa tgtctctcac ataatcttga cgattatctt gtggaatctt tccgttaatg
    15841 cgacagtaac ctgatgtagg ctttaaaata cctgttaaca tcttaatcgt tgttgatttt
    15901 cctgcaccat tggcgccaat aaaacctaaa atttgccctt tgggtacctc aaaagataag
    15961 tccttaaccg cctcaaagat ttctctttgg ggatgaacaa aggacttcaa ggctcccttt
    16021 aatcctggct ctttaatggt tttggaaaaa tttttttgaa ggtgggacac ttctatcatg
    16081 accatttacc attcctcgtt tctgttatcg tcttatcacc gttactaaac aatttattat
    16141 aacaccatga aaaagactgt gcaaccgttt gcttaatttt ttaagaaaga aaaagaagcc
    16201 cataaggacc tctttttgcc attgattaag cttgtgcatc tggacatgac ttgcgagcaa
    16261 tgtctgccaa gatgttttcc acaaattctt ccacagattc agtgtgagtc gccttactac
    16321 catagcggcg aacattgact gatttgtctt ccatttcttt gtccccaaca attaattggt
    16381 aaggaatttt gctggtttga gacgcacgaa tcttgtactg cattttttca ttgcggtcat
    16441 cgacatctgc acgaacacca cggtcacgaa gggtttttgc tacttcccaa gcatagtcaa
    16501 tgtgggcttc atttgaaatt ggaatcacgg ttacttggtg aggtgccaac caagttggga
    16561 aagcaccctt gtaagtttca ataaggatag cagtgaaacg ttccatagtt gagataacac
    16621 cacgatgaat catgactggg cggtgttctt cgccatctgc accaatgtat ttaaggtcaa
    16681 aacgttctgg caacaagaag tccaactgaa tggttgatag agtttcttcg ttaccaagag
    16741 ctgttttcac ctgaatatca agcttaggcc cataaaaggc tgcttcacct tctgcttcaa
    16801 agtaatctac acccatctca tcaagtgcag ctttaagcat actttgagca ttttcccaca
    16861 tctcatcatt gtcataatat ttatgagtat cgttagggtc tcggtatgac aaacgaaaac
    16921 gataatcagt caagttgaag tcagcataaa catcaatgat taattgaagg gcacgttgaa
    16981 attcttcctg gatttgctct ggtgttacga aaatgtggcc atcattcaag gtcatttcac
    17041 gtacccgttg aagtcctgat agggcacctg atttttcgta acggtgcatc atgccaagct
    17101 cggcaatacg aataggcaat tcacgataag aacgcacatg atttttatac acttgaatgt
    17161 ggtgtgggca gttcattgga cgaagaacaa actcctcacc atctcccata tccattacag
    17221 ggaacatatc ttcttgataa tgatcccaat gacctgatgt cttgtacaat tctacagaag
    17281 caagtggtgg tgtgtaaacg tgttggtagc ctgatgctaa ttctttatct gtgatgtagc
    17341 gctcaagtgt acgacgaata gtcgctccat ctggtaacca aaacggcaag ccttgaccaa
    17401 cttcttggct aatcatgaac aagtcaagct ctttaccaag cttacggtga tcacgttctt
    17461 tggcttcttc tagacgagtc aagtaagctt tgaggtcttt tttatcaaac caagctgttc
    17521 catagatacg ttgcatcatg ttattgtcgc tgttaccacg ccagtaagca cccgccacat
    17581 ttagcaagtg gaagacttgg atacggcctg ttgatggcac atgagggcca cggcaaagat
    17641 ccacaaattc accttgacgg taaaccgtca agccagcacc agcatgctca ttaatcaatt
    17701 ctaccttgta aggatcatct ttgaacaatt ccaaagcttc ttctttggtc acttcttcac
    17761 ggatacatgg gtaattttct gtcacgattt tttgcatttc agcttcgata cgtggcaaat
    17821 cttcgtttga aatttggcct tctgcattat ctgtatcata gtaaaagcct tctgcaatgg
    17881 cagggcccac acccaaatga agatttggga acaagcgttt tgcagcttgg gcaaataaat
    17941 gggctgcaga gtggcgaagc acctcataag catctttgtg gtcaggtgtc acgatttcaa
    18001 tactgccatc ttcttcaatg gcacgagtgg tgtcaatgag ttgatcattg aacttaccag
    18061 ctaaagcttt tttagccaat gatttgctga tggactcagc aatgtcaaac gttgttacgc
    18121 cagattcaaa ttcacgcacg gcgccatctg gaaaagtaat cttaatcatt tgctttctcc
    18181 tttaagtcag ttaagatttc cactaaaaca tggatagtaa gacaaattag ggacaagagg
    18241 ttagtgaata gctcaatacc accacgtaga agaacaatac cttattcacg aatctaccct
    18301 ccctagtcct taaaaacaag gctaatcccc tccaaaacaa aaaaactgac cgcatcccaa
    18361 aggacgcaat cagcgtggtt ccaccttaat ttatgcagga caaaaaacat gccttgcacc
    18421 tctagtggcg ataagggggc caccctttta tgtttgcata aaaaccagga aggagtatca
    18481 gattagctat ccttgtgctc tttccaccaa ccagcactcg cttaaaagat tctgtccaat
    18541 ctaacttgtc ttcaagatta ttatagcaag ttttcaaaaa tttacaagcc ttaatccaga
    18601 aaatctttga tagcatggac cagcttgata ggagccttga ctacttttac tgaggtgata
    18661 gctgtgacct tagcagcacg tttaggcaag tgaatagcac cttgcactaa ttttagagaa
    18721 ctacttttac cagaatgatt aagataaaga ctcaactttt gagcttcttt gctatttcta
    18781 gcaattaacg tatctaaata gaacgtgtaa atagattttc caaagtgctg tgctgagatt
    18841 tcataacgtt tttttgctaa taaccgttta tccataactg gtgtttttag tatggcatca
    18901 ataatagcat cagttaaatc tgtttcagcg taataaagag tgccaaacat tttatcagtc
    18961 accacatcat ctaaataagg attgccatga gcaataatag gagtgccact agccaaactt
    19021 tcaatatagg tcaagccctg agtctcactg gtcgatgctg agataaagaa atcacaagcc
    19081 ttatagtaca gagcaacctt atcatgaggc accatgcctg taaaggtcac gtgtttgtca
    19141 acctctaact gcatcgccaa gtgtttcaaa tcttgcaaat aggggccatc tcctacaata
    19201 ataagcttta tcttggcatt ttcagccaaa atagctggca tctgattgat gatagcttga
    19261 atattttttt cataagaaat ccgtgacaaa ctcaataaca tggtttcatc accagcaatg
    19321 cccaattctg cttttaagtt ggttacttct tctgctgtga tgtcatcacg aatatatttt
    19381 tccaaaggaa tgcctgttgg gataacccgc ttagggatag tcacttcgta accttctaga
    19441 agattgagga caatcctact tgggcagata accccatcca aatccttcaa atagccccta
    19501 agaagaggtt tgaccatact tggtcgaatg atttttccgt tggcaatata actcacgtag
    19561 tcctcatatt gggtatggta agtatggaca acaggaattc gcaaagcttt gcctatcatt
    19621 ttccctaaca agcctaagct aaactcagtt tgcgtatgaa taatatcaag attatagtgt
    19681 tttgcaattt tgtatgacga aatgaggccg cgataaacca cacgtctatc cgtaaatgac
    19741 acaaaaggaa cacttggcag tcgaataatg gtcgggtctt caaagcgttt gacatctcta
    19801 tcagtagtgg tgaaaatata aacttcgtga ccttcttttt ctagctcttc ttttaacgta
    19861 cgaatactag tagcgactcc tgaaacttgt ggaaaatagg tatctgtgaa tagacctata
    19921 cgcatcttat aactccatta cttttttata gacatctact aaggcatggc caaccgtttc
    19981 taggcgacga ctctgggcaa ccttgtaacc agcttcaact ttgttgctgg caccagaaaa
    20041 gacttttttc agagcttcta taaaacctgg tatatcggtt gctaattccg cactactttg
    20101 atcaacccat ccgtagtaaa ctggtatatc acgtaaaaca aggtgctggc gactggccaa
    20161 ggcttctaag acaacaatgc cttctgtttc ttcacgactt ggaaagaaaa aggcatctgc
    20221 accagtcatg gcaccttcat aaacatctcc tttaatgtat cctgggaaaa taagattttt
    20281 cgggtggtta ccattgacca tttggcgaac ttgagcagga atgacccatt tgttggtctc
    20341 gccaaaccag ataaaacgaa catctggcat agcttgggca actttgacaa agtcatcaat
    20401 tcctttcctc agaaaaaata atcctgctcc cataaccact ttttcatcct ctttaatgtc
    20461 aaagtagcga cgaaaagctg cttccttttt aggatctgct ccgtactgct ccaaatcaat
    20521 cccatttgac actgcaaaaa taggtgactt cactccataa ctctcaatca aagacttaga
    20581 atatagggta ggggtaatga tagcatctgc cttattgtaa aagtgacaaa ggtatttttt
    20641 aaaccaagga gataatagat ttgaaaaaat aaaagaattt ctaaaatctt cttctgtaga
    20701 atgcccatgc atgataacct tcttaccagc tttttgtgct tttatcatca gcagccaact
    20761 ttttaaacca taggtattga gatgaaccaa atcataagtt tctcttggat tagtcgtaaa
    20821 atgttgacca acaagtgaca aggctttagc ctgatgctta atcgctcgac caattcctga
    20881 ttttcttaga taattttctg cttctaaata caataagact ttcatgagtt ctattatagc
    20941 tcattttata gtatttttca ctaagacatg caaaaatcag ccctaaggct gattttagta
    21001 ttgaagaaac agtctattgt gatacttttt gttagatggt gctcataagt cacagttact
    21061 tagttgtccc acgtttttta ataccatgat tcaaaagaat ttctttttct tccaactctt
    21121 ctttgttcat gattttagtc aacatccgca tgctaacagc acctaagtca taaacaggtt
    21181 gactgataga actcaaatta ggacgagtgt attgaaccac tggtgaatcg ttgctggtga
    21241 tgatttcaaa gtcctctggt acgcgtttac ctgcttcaaa caagccgttt aaaaggcccg
    21301 ctgccaattc atcttcagcc acataagccg ctgttgctcc tgagttaatg acgcgctgcg
    21361 ccaattcaaa tccttcttta taagaatagt tcgcttcaaa aacaagacct tctttgaagt
    21421 caagcttatt gtgcttcaac ccttctttgt aacctgctaa gcgcacttta ccattgatat
    21481 catcaatgag tggtcctgac acaaaagcga tacacttatg attttcagct aaaatatcaa
    21541 caacatttga caccgcagct ctatagtcaa tgttgacgct tggtaattga tgatcaagat
    21601 ctacagttcc tgccaaaaca actggagtac gagagcgtga aaactcggcc cggatttttt
    21661 ctgtcaagtg atgccccata aaaataatac catccacttg cttggcaaaa agggtattga
    21721 caacattaac ctccttatca tcatcttcat cactggaggc aagcacaata ttatatttgt
    21781 acatagcggc gatatcgtca atacccttag ctaagataga aaaataacta tttgcaatat
    21841 ttggaatcac aacgccaacg gttgttgtct ttttgctggc gagaccacgc gcgacagcat
    21901 tgggacgata gtcaaggcga tcaataactt ctaaaacttt cttacgtgta ttttccttaa
    21961 catttttatt gccattaaca acacgactaa cggttgccat tgaaacacca gcttcacggg
    22021 caacatcata aattgtaatg gtatcatctg tattcatttt ttatcttcct ttctatttga
    22081 aaatgacgct ttcaaaaagt attttagcat gatttgtaac cactttcaag tgttataggt
    22141 taatttttga aaaagttttc aaaaattaac tcgaagcttg attttttaag ctttttttga
    22201 aaaaatagta agtagaaaga aggttagcct atgacaaaat tagaccaaat acgtttgtat
    22261 cttgaccaaa agggagctga attggcgatt ttctcagatc ctgttacgat taactattta
    22321 actggattct tctgtgaccc acatgaaaga caactgttct tgtttgtcta ctatgattta
    22381 gctcctgtgc tttttgtacc tgcccttgag gtggccaaag ctagccaggc catatcattt
    22441 cctgtgtttg gttatgttga ctctgaaaat ccttgggaaa agatcaaggc cgttttacca
    22501 aatacagcag ccaaaaccat ttatgctgaa tttgaccacc ttaacgtcaa taagttccat
    22561 ggcttgcaga ctatcttttc agggcaattt aacaatctaa ccccttatgt ccaaggcatg
    22621 cgcctcatca aatcagctga tgaaatcaat aaaatgatga ttgccgggca gttcgctgat
    22681 aaggctgttc aagttggttt tgacaatatt tccttagatg ctaccgaaac agacgtcatc
    22741 gctcaaattg agtttgaaat gaaaaaacaa ggcattcata aaatgagctt tgacactatg
    22801 gtcttaactg gaaataatgc agccaatccc catggcattc ctggaacaaa taacattgaa
    22861 aacaatgccc tacttctttt tgacttaggt gttgagacct taggctacac cagtgatatg
    22921 accagaactg tggctgttgg tcagccagac caatttaaaa tcgatatcta caatctctgc
    22981 ctagaggcac aactagcggc tattgacttt atcaaaccag gtgtaacagc tgctcaagta
    23041 gatgctgctg ctcgtcaagt gattgagaag gctggatatg gtgagtactt caaccaccgc
    23101 ttgggacatg gtatcggcat ggatgtccac gaatttccct ccatcatggc tggcaatgac
    23161 ttggtccttg aagaaggtat gtgcttctct gtggaaccag gcatttacat tccaggaaag
    23221 gtcggtgtgc gcatcgaaga ctgtggccat gtcactaaaa atggctttga agtctttacc
    23281 catactccaa aagagttgct ttattttgaa ggctaagccc ctatcatctg attaaacaaa
    23341 ccctcgcgaa aggaaggtat tcgtatggat caaaccattc atcatcaatt acagcaagca
    23401 ctacacttta ggacagccgt tcgtgtttat aaggaagaaa agatttctga tgaggattta
    23461 gcccttatcc ttgatgctgc ttggttaagc ccttcttctg ttggcttaga aggctggcgc
    23521 tttgtcgttt tagacaacaa gcctataaaa gaagaaatca agccctttgc ctggggggcc
    23581 cagtatcaac tagagacagc tagtcacttt attcttttaa tagctgaaaa acatgcaaga
    23641 tacgatagcc ctgctatcaa aaatagcctt ttacgacgtg gtatcaaaga aggtgatggt
    23701 ctcaacagcc gcctaaaact ctatgaatct ttccaaaaag aggacatgga tatggcagat
    23761 aatcctcggg cactctttga ttggacagct aaacaaacct atatcgctct tggtaatatg
    23821 atgatgacag ctgctctttt gggcattgat acttgcccta ttgaaggctt tcattatgat
    23881 aaggtcaatc atatcctagc taagcataat gtgattgatt tagaaaaaga aggcattgct
    23941 agcatgttat ccctaggcta tcgcctgcga gatcccaaac atgctcaagt tcgtaagcct
    24001 aaagaagaag tgatttcagt cgttaaataa ggagattaaa atgaaagcat tacatacctg
    24061 tatccgcgtc aaagaccttg accagtcggt tgctttttac acaagcgcct tcccttttaa
    24121 ggaaaactat cgtaaagatt ttccagatag tcaatttact cttgtttatc tggctttaga
    24181 aggagaaagt tatgaattag aattaaccta caattatggt catggcgact acgacttagg
    24241 aaatggctat ggtcatattg cccttggctc tgaacatttt gaagcagacc ataaaaaaca
    24301 tcgacaagca ggttttccag ttaccgatat caaagaactg gctgacaaat ctgcccgcta
    24361 ttatttcatt caggatccag atggctacaa aattgaagtc attgatttaa acaactaata
    24421 ctattaacaa cagaagcttt aaagcttctg ttgttttatt ttttaacctg acgattggga
    24481 caatctcatt attaacagag ttttgaaata tctcagcttt tgtgttacaa ttgccctaaa
    24541 attccatttg aaagaaaagt ctatgacact attatctatc attgtcccct gctttaatga
    24601 agaagcaaac attcttcctt attttgaaga aatgcatcaa ctagaaacgt ccatgaccaa
    24661 ccaacttgct tttgaataca tttttattga tgatggttct aaggataaca ccttaggtat
    24721 tttgcgtgag ctagctgctc gctttccaaa tgtgcattat ctgtcttttt cacgccattt
    24781 tggcaaggaa gctggactct tagctggact aaaagaagcc aaaggcaatt acattactgt
    24841 gatggatgtg gatctgcaag atccacccga acttttgcca gttatgtacg ctaagctaaa
    24901 agaaggttat gacatcgttg gcaccaggcg ccaaaataga caaggagaac cactaattcg
    24961 ttcaatgtgt tcgaatctat tttatggact gatcaaacac ttatcagata ctgaaatggt
    25021 caatggagtt cgggattatc ggttaatgac cagacaagtc gttgatagca ttcttgagtt
    25081 gggagaggtt aatcgttttt caaaagggat cttttcgtgg gttggttatc gtatcaccta
    25141 tcttagtttt gaaaaccaaa aacgcaaata tggaaaaagt cgttggcatt tttgggagtt
    25201 gctccgatat tctttagatg gctttatcaa cttttcagaa atgccgttaa ccattgctac
    25261 ctggacaggg actttcagct ttttgatttc tattttcgcc atcttattta tcattatcag
    25321 aaagatactc tttggtgatc ctgtctctgg ttgggccagc actgtctcta ttattttatt
    25381 catgggaggc attcagctct tttgcatggg tattattgga aaatatattt caaaaatatt
    25441 ccttgaaact aaaaaaaggc ctctctatat tatcaaagaa aaacattaaa ttaaaacatt
    25501 tttctcatca atcgtttcct actccttctg tgcgcgaagc tttcttttta agcccgttat
    25561 accaaatgat aatgaccttt ccaaaatagt atcaccttcc ttaacacttt aagtagaaaa
    25621 ggaactatta ggttgagcct ttttgcaaat cctagcgact aatgttataa tcgtcatact
    25681 attgaaaaag gagttcttta tggagtggat taaattaatc ggtattgtga ttatcgtgtt
    25741 agggtttatt ttaaaatgtg atgctatcgc taccgtagtt gttgcaggac ttgttaccgc
    25801 gctggtttca ggaatttcgt ttattgattt tctagatatt ttaggaaaag aatttaccaa
    25861 tcaacgtttg ctaaccattt tcttcatcac tttaccgctt atcggcttat cagaaactta
    25921 tgggctgaaa caccgagcta ctcagttgat tcaacgtgtt caatccctta ccgtcggccg
    25981 tttattgact ctctacctta ttattcgaga attagcaggt ctcttttcga ttcgactagg
    26041 gggacatcca cagttcgttc gccccttgat tcaacctatg ggagaagctg ctgctaaagc
    26101 caacattgga gaagagttga ccgatgcaga aaaagatgac atcaaagcta tggcagctgc
    26161 caatgaaaac tttggcaatt tctttgccca aaataccttt gttggcgcag gaggtgtcct
    26221 acttatcgct ggaactctag aacagcttgg ctatgatggt aaccaagcta aaattgcatt
    26281 ttcttctatt ttaattgcta ttatctctat tattatagtt gctatttaca attacctctt
    26341 tgagaaaaaa atggaacgtc aacatcagaa aggagataac taatggctaa cattgcaaac
    26401 cttgttttag aaacgatata tatccttatc ggcttgcaac tgtttcacac agcctactgc
    26461 acctttaaag ataaaaccaa ccctgtctat tttgggacag ctctgttctg gggattgctg
    26521 ggtgttacct tcgttggcgg tgcctttttg cctaataaag ttatcggttt tatcgtgatt
    26581 gtcctagctc ttttaacctt gtttaagcaa gttcgtattg gaacattacc agcctttaat
    26641 gaacaaaaag ctgaagaaag tgctcaccgc attggtaact ggattttctt accagttatg
    26701 ttaatggcta tgatttctct acttcttgcc ttgatccttc ctgatttcag taaaagtgcc
    26761 attgggattg ctggtatctt agccactatt gctattttaa taatcactaa gcaaaaacca
    26821 tctgctcttt tagctgaaaa taatcggatg aaccaacaag tgtccacaag cggtattttg
    26881 ccacagctct taggagcttt aggagctatt tttgcagctg ctggtgttgg tgatgtgatt
    26941 gcttctctca ttcgggagat tgtacctgct gatagccgct tctttggtgt tctcgcttat
    27001 gtgcttggca tggttatttt tactatgatt atgggaaacg cttttgctgc ctttaccgtt
    27061 attacaaccg gtatcggtgt tccttttgtt tttgctttag gagctgaccc tattattgcc
    27121 ggtgctttag ctatgactgc tggtttttgt ggtaccttat taacaccaat ggcagcaaac
    27181 tttaatgcct tgcctgttgc tttgatggag atcaaagatc gaaatgcagt tatcaaaaag
    27241 caagctccta tcgcccttgt tttaattatt agtcacattg ccttaatgta tttacttgct
    27301 tattattaac ttttttgcta agttagtagc gtcagttatt cattgaaagg acattattat
    27361 gaaaattctt gtaacaggct ttgatccctt tggcggcgaa gctattaatc ctgcccttga
    27421 agctatcaag aaattgccag caaccattca tggagcagaa atcaaatgta ttgaagttcc
    27481 aacagttttt caaaaatctg ccgatgtgct ccagcagcat atcgaaagct ttcaacctga
    27541 tgcagtcctt tgtattgggc aagctggtgg ccggactgga ctaacgccag aacgcattgc
    27601 cattaatcaa gacgatgctc gcattcctga taacgaaggg aatcagccta ttgatacacc
    27661 tattcgtgca gatggtaaag cagcttattt ttcaaccttg ccaatcaaag cgatggttgc
    27721 tgctattcat caggctgggc ttcctgcttc tgtttctaat acagctggta cctttgtttg
    27781 caatcatttg atgtatcaag ccctttactt agtggataaa tattgtccaa atgccaaagc
    27841 tgggtttatg catattccct ttatgatgga acaggttgtt gataaaccta atacagctgc
    27901 catgaacctc gatgatatta caagaggaat tgaggctgct atttttgcca ttgtcgattt
    27961 caaagatcgt tccgatttaa aacgtgtagg gggcgctact cactgactgt gacgctaata
    28021 aacctatttt aaaaaaaaca gagatatgaa ctaactctgt tttttttgtg ctaaaaatga
    28081 aagacctagg gaaacttttc ataggtcttt ctcaattgtc atcttaatct aatactactt
    28141 ctaacatcag cgggtatagt ttgccagtaa ttaagaaacg ttgttgatct aaatgagcaa
    28201 tcccattcaa aacattaagg tcagggtaat gggacttatc aagatttaag gcttttaaca
    28261 aaggactaat atcataggtg gctaccacct ttccagaatc aggttggagt ttgacaatag
    28321 tattggtttg ccaaatattg gcatagagat aaccatctac atactctaat tcgttaagca
    28381 ttgagatggg gacactttct atagcaacta gtacggtatc caataaagta aaatctttgg
    28441 ggtctcgctt ttgcaaaaaa gcatttccac tagtcatcca aagacactgg ttttccttat
    28501 cataggctaa tccccagcca tctccttcaa atggataggc ccctaaacaa ttgcagatag
    28561 ccttatcaaa cttgtaggct acaccctctt tataggttag taaccaaaaa taatcctcaa
    28621 caactgttag cccttctgca aaaactgtat ctggaaaagc tattttttct gaaaagatct
    28681 cttgagtaag gtcatacacc cctacttttg agaaaccata acgaccggca ctaagtaata
    28741 tatgattgtt gttgagttgt tctaatccct gcgtgtataa gttgctatca taagaataag
    28801 ttcgtaacaa acgaacttgt cctttagtta tcataatact cattcacctt accttgcatt
    28861 gtagtgtttc atttgttttt ttatatctct ttcctgatca cggcgtttaa tggtttcgcg
    28921 tttgtcatac tcgtgtttcc ctttagctag accaatcaga actttagcaa agccatcctt
    28981 gaggtaaact ttgagaggaa ctaaggtcat gccagatcct ttaagttcat ttgctagatg
    29041 cgtaatctca cgttttttga gcaacagttt gcgggtccgt tcaggatcag cgttccaaat
    29101 attaccttgt tcaaaaggtg caatatgcac gttgaccaac cacgcttccc cattcttaat
    29161 ttgggcaaag ccatctttca gttgaatacg agctgcacga acacttttaa tctcagttcc
    29221 cgttaagaca atccctgctt caacggtttc aacaatgtga taatcatgtc tagccttttt
    29281 attttgcgcc agtatatgac cttcaccttt tgccatagtt aactcctttt acgactcttc
    29341 ttttttgctt gttctttgta aaatggtttt ttagaccctt ttttagtttt acccttggtt
    29401 tttgccttgg ctacttcttt aggttctttt ttctttatcc ctttagatga ttttgaggat
    29461 ttacggcgat ctcgtcgact agctttatcc gacatcttga ttttttcaac cacatcaaag
    29521 tcgctaggta aatactcaaa gtcaatgtca ccagtttcct tgtcagcctt aaccaatttc
    29581 acacgaatag gttgaccaac tttaaagact ttacctgatt tttcaccttg aaggcttagc
    29641 gttctttcat taaagtgata gtattccggt aagctagtga tatgaaccaa accttcaatc
    29701 gtatttggca attctacaaa aaaaccaaat ttaacgacac tggaaacgat accgtcaaat
    29761 tcttcgccga catactctgc catatactca gcttttttca tggcttcaac cacgcgttca
    29821 gcatcaatag cacgacgctc taactgtgaa gaagatgttg ccagctctgg aatgatctga
    29881 gcaaaatggt cgcgcttttc ttgactaggt tgattgtact cacgaatcat gcggtgaacc
    29941 aacaagtcag ggtaacgacg aatcggactg gtaaagtgag tgtaatattc tgcggccaaa
    30001 ccgtaatgcc catgattatg ttcagaatat cttgcttgtt gcatggaacg tagaagcatc
    30061 atgttgagca cttctgctcc tggttgacct tcgacttttg ccataaaggc ttgcaaggct
    30121 tcctgagaaa tcttgttggc tgttccttga atgtgaatac caaaggtgct agcgtagtca
    30181 ataaattgtt gaagtttttc aacctttggt tcttcgtgaa tacggtagat aaacggtaac
    30241 ttagcttttg caaaatgttc tgccacacac tcattggctg ctagcataaa ggactcaatc
    30301 atccgctctg caattcccct ttgacgaagc accacatcaa ccggcattcc tttgtcatta
    30361 acaataactt tagcttcttg cgtatcaaaa ttcaaggcgc ctcgttttga ccgcatcgtt
    30421 tccaaaatcc tatgcaaagc caccatgagg gtcacatcat cagcaatgct agcgaattct
    30481 tggagcgctt cttcatctcc tgcaatcatg tcattgaccg tactatacgt cattcggtaa
    30541 gttgtcttaa tcactgattg acagatttga taattgacca catacccctg cgggttaatt
    30601 tccattaagg ctgactgggt caaacgatca acgttagggt tcaaagagca gatgccattt
    30661 gacaaacgct ctggtaacat cggaaccaca cgatcggtga catagacaga agtgccacgg
    30721 gcgatagctt ccttatcaag ggaagatcct tctgtcacat aatatgagac atccgcaata
    30781 tgtaccccaa gttcatagtt accgttatcc aatagcttaa tatggatagc atcatctaag
    30841 tctttggcgt ccgcaccatc aatagtaatg gtggtttctt gacgcaaatc cacacggcct
    30901 attaaatctt tagcagttgg tgcttctgaa atagcattgg cctcggctaa aacttctgct
    30961 gggaactctg acacgatatc catcgattca aggacttcta ggacatcaat tccaacgtct
    31021 ccttgatggc ctacgatatc acgcacactg gctacaaaat aatcgtgccc gcgtgtcggg
    31081 tatttatcaa tatcaacctt gatgatttca gtgcctttaa gcacaacagg ttcttttttg
    31141 atatagattt tttgttgaat cttttgattt ttggacctga tataaccagc atattttggt
    31201 ttgtcatcat ctaaaataaa agttccaaca gctgttttta aagaacggtc aacaatagca
    31261 acaaccttag cttcagccgc tgtgcctttg agacggtctg ctggcttttt aaccactact
    31321 tcgacagtat caccatcaat agcataccca acatcattac gaccaataaa catatcgtct
    31381 tcattctcat ccacatgtaa gaaaccaaag cctgctttat tggcacgaaa aacaccctga
    31441 acagtaggtt cttttttctt ttcacgctct tttctaagag ccagactgcc atcatctgaa
    31501 aaccgtaaca ggctctgact ttccattttg gaaatggttt taataaggct gggaaaatgc
    31561 ttagctccag ccatctccaa ggccgcagcc aagtcgttca cattggactt gccatgctcc
    31621 ttgaggtaag tcataattct ttctttcatc atacctaatt tctatttctg ttttgtttgt
    31681 tggaggatat caatccgttt cgctgataaa aaaatgagct agactaactc tgtcaagctc
    31741 actccttatt tacttgataa aatggcaagc acaagtgcaa tcgctagcca aaaaaatact
    31801 agaactgctg tgaatcgttg catgaatgct tcaaagccac gagcttttgt acgttcaaac
    31861 aaggcttctg aaccgctgct atcaaaaaca ttgctacttg ggtttttttg aggttgcata
    31921 aaaatagcaa tcacaagcaa taccgacagt actagcaata tcgtaagtag taagttgtac
    31981 atgttatttc ctccactatt gtcatgacca ttttaacaca attcttatca agtttcaaca
    32041 tgcagggtca cttttctctc cttggggcag tatttgggaa cttttatttt ttccggatga
    32101 ctgcttttat ttttactggt tagataattg ttactgccac actcactgca ttctaaatta
    32161 atttttactc tcacacaata tccttaactt taatatattt tcgaaatata atcaaactcc
    32221 atattaaatt aacaaacaca atcaaactag tcacataaaa aacagaacgg tagcctaaca
    32281 ctacagccac atttgatccg ataaaagggc caatgacttg accaaggtta ctaaacattt
    32341 gattataggc aaatactcta gaaatacctt cttttggtgt taacttagtt agtaaagagt
    32401 taatacttgg catcaaagcg cccacaccaa acccataagc aaagcgtagt actcctaatt
    32461 gaaaactggt ctgcgctaag gcactgctaa aatacatgat aaagctataa cacaaagcgg
    32521 ctaacaataa ccgatgattg ccaaatcgat ctcctaattt tcctaagtaa gaactgctaa
    32581 ataagctaga aaaccccatg gccgaaacta ccaggcctga agtaagcatt aagttgtgag
    32641 tttgaccaag atgacgaata tacaatgata aaatgggggc cactgattga gctgagattt
    32701 gaataatcat actagtcaca aataaaccaa gcataatctg gggacttttt acctgtttta
    32761 aaatgacttt tgtaggtatc atctcaaagc gcctaaccgg cttaaactct tctttaacat
    32821 aaacagctgt cattaaagaa cataaaaata atatcacacc aactaataag aaaacttgtc
    32881 gaattcctaa tagctctgcc aaaattcccc ctagtaaagg accaattaaa gcgcctgctg
    32941 tcactcctgt tgctaatgtg cctaaagcat aacctgactc ctcttttggg gcttggctgg
    33001 caatcaaggc agtggcattt ggcacatagc ccgcaaagac acctgttaat aatctcaaaa
    33061 tgagtaacca aaacacatta ggaataatag ctaaaccacc cattgtaaat gtcatgacaa
    33121 aacttgctcg cagcatcata ggttttcggc cataacgatc agccaacttc ccccaaacag
    33181 gagcaaataa agctgaagca agtgccgtca cagcaaccgc cagaccagca tagtattcta
    33241 ctaattcttt cggagtacct aaattttcca catatagagc cataaaaggc ataacaagtg
    33301 aaaagcttgc cccagtaaag aagttaccaa gccaagccac ttttagattt tgtcgccagt
    33361 tcactgtcgt taccgcttta tcactaatag atcatcatct tctttccatc gggcctttga
    33421 ttattataac acatttctgc caaaaacagt gtcccataat agtgctaagt ctcatctgat
    33481 agccttcatc gtttacgtaa actacccagt aaacctctga ccagttctcg cccaattgtt
    33541 ctaaccgtcg tactaataaa cgcatctgtt gctttttcga cgactgtttt gcggggacgc
    33601 ccaacagaac ggcgactagt cttttcagca gcagcttgtt ccttgatggc ttctttagct
    33661 tctttttcgc gttgtgctgt cgctatcgct tcttgggcca gtcggttgtc ttctaaaacc
    33721 ttagcagcta atttttcata agcagagtca cggtcaatgg actgagtata tttaccggca
    33781 aaaggtgagg actgcacaag ctgctgactt tctatctctg acaaaacagc aaagctactc
    33841 ttaggcggca tgatataggc acgttcaacg atggatggtt gtcctttttc atttaaaaca
    33901 gaaatcaaag cttcgccgac ttccagttct gtaatcaccc ttgccacatc taagtcagga
    33961 ttttgtcgga aagtatccgc agcgacacga accgcctttt gttctttcgg tgtataagca
    34021 cgcaaggcat gctgaatacg atttccaagc tgagccaaaa ccgtttctgg caaatcaagt
    34081 gggttttgag tcacaaagaa aatcccaact ccctttgaac gaataagtcg cacaatctgt
    34141 tcaacttttt ccaagaaaac tttaggggca tctttgaaga gcaagtgagc ttcatcaaaa
    34201 aagaaaacca tcttaggttt gtccaaatcc ccaacttctg gcaataattc gtacaactca
    34261 gacaagagcc aaagtaagaa ggttgtgtaa agggtaggag attgaaaaag cttagtcgct
    34321 gacaaaatgt taatggctcc ataacccgaa gcaacatcta attgcatcaa atcagccaca
    34381 tctaaagcag gctctccaaa aaattggtgg gccccttctt gttctaatgt caagagactt
    34441 ctttggatag ccccgataga ttgcttggcg atattaccgt aatggctgga gtagtctgag
    34501 gcatggtcac caacttcttt taagatagcc tgcaagtctt tcaaatcaat caaaagccaa
    34561 cctttctcgt cggcgatttt aaagacgatg tttaagacac ctgtctgggt atcattaaga
    34621 ttcaataaac gcgacaacat cataggtccc agctcagaaa tcgttgtccg taagggttga
    34681 ccgttttgac caaaaacatc ccacattctt acaggaaagg cctgaggctg gtaatcactt
    34741 accccgattg tggctaaacg cgcagccaat ttatcagtca cctctcctgc tttagtaaga
    34801 ttagacaggt ctcctttgat atctgccaaa aagactggca caccagctaa acttaattgc
    34861 tctgctagca cttttaaggt cacagtttta cctgttccag tcgctccagc aatcaaaccg
    34921 tgacgattta gcatccctaa ttgtaaggct atcggttgat tgccttttgc aattgtcatt
    34981 gtagtcatag gcttcctctt ttttgatgat catacttgtc gatatgtgtt tacccataag
    35041 ttaaagtgtt tagaagggtc tcactcttaa tactattata acatataacc cttgatgcgc
    35101 taatttaaaa gggaccagct agttttagac agaaatagct tgattttgac agctatgata
    35161 cgaatctctc agcttagcta cctcggattg gctaatgaca acaacgcaga ttgtacttgc
    35221 tttattaagg ctgcaatatc cccactatta tcaatcacta gactggcata gggctttttt
    35281 tcctctattg gtaactgact ggctattcgc tgccttgctt ttcctttgtc taaacgattt
    35341 ctagccatta agcgctgcaa ttgtgtctga gcatctacat aaaccagcca aatcgcatca
    35401 aaccagtctt ggtagcccaa ttccattaaa aggggaatat ccatgaaaaa aatggcttgg
    35461 ctctgtgcta agtggtcacg cttagccgcc aattcttcct taatgatttg attttgaatg
    35521 gctgaggatg ttgccatatt atctgggttt gaaaaaagca tttctgacag ctttgtgcga
    35581 tctaactcac catctgcttt taaaatctga ttcccaaaag cttctctaag agcctcgtaa
    35641 agacgaccgc ctttttcttg caagtcatgg accacttgat ccgcatcaat cacctgataa
    35701 ccagcttttc taatgacctt aaccacagtc gattttcctg atgcaatgcc tcctgtgatg
    35761 ccaataatca tggtcttttt ttctggcatt ttggacaaat gtgcgtcccc cttcctccaa
    35821 cttttaattt gacaatagcc tgtccacaac gaggacacgg tttcccagtt tgaccataaa
    35881 cctgcaaaca gtcctgcatg gtgccatcag ctcccaaagc attacggtaa gtacggacgg
    35941 tcgaaccgcc cttttcaatt cctaaagcta ggattcgtat ggtttcatca tgcagccgtt
    36001 ttatctccgc cttattcaac ctagaagacg cagtttctgg atgaacctta gcagcccaaa
    36061 gtacctcgtc cacataaata ttccctaaac cagcaaccaa ggtctggtct aacagatgtg
    36121 gttttatggg tttttgggag gatagcagag cagcctcaaa ggtttttaac ttaaaggtct
    36181 ctttctttgg ttcagggcct agttttcgtt tggcaaaaaa cgctgataat tgagattttg
    36241 ctatcaaatc aaaggttcca aatttacgca catcttggta aaccaaggtc gaaccatttt
    36301 tcaattcaaa aaagacatga aagtgtttgt tatcagggac ctcatctgga aaaagcaaat
    36361 atttgccttc catccgcaaa tgtgatacca acactaattg ccccaaatca attaataaat
    36421 attttccccg acggccaact gactgaatga tttgaccagg tagggtcagg gcaaacgtct
    36481 ctaagtcggt tttaaccatt tttggcactt taagcgtaac agccacaatt tcttggccaa
    36541 gcactaaagt ctcaagccct cgtcggaccg tttcaacttc tggtaattct cgcataatcc
    36601 gttatttaaa ggacagctag accctttgct cctacaaaga ataaactcag tataaaaaag
    36661 tcactcaata gactcaggtc taggctactg actgcgtttc aaaaaacaca gctgtccttc
    36721 tcctttctta tttcttattt tacgaacaca tctgatagaa agcaactcat aaatctgcct
    36781 cagaccagtc ctcatccccc ttacctccca gcactatttg gcggtaatgt tccttataac
    36841 tataatacaa tgagtcctct ccaagatact taaaaatctg caaggcctgc cgcatgtcct
    36901 cttctccaga aatttcttcc tgctttaatt tataataccc atgcacatat aagaaaacag
    36961 tcttttcata aaaattgagc tcgtctcgca gcaaaagatc aattttgtta atcaaatagc
    37021 gactatgttc aaagcaagaa tggtcaatac tgataatgag acaattaatg gataactgag
    37081 tcactaacat tttattggtt ttattttgtt ccgaataagc aaaagatgct accatttcct
    37141 tagtcaataa aaatagggta ttgtaattca tgaagcgcga gcaattcccc agaagaatga
    37201 tttcataata tccccactgt tccactttaa ataaataatc tgtgaggcga gtcaattctt
    37261 cttgactagg tgcaattgag gagtcaatag aaaaaagaat agctttaatc atcgttcgtt
    37321 cataatcttt atgggcataa tccttcaaca gtttggtcaa tttaaccacg tttttctcag
    37381 cataacattt tctcgcctga cttaagagcg tgaaaaaatg cgtatgcgtc ttggaatgag
    37441 ccgaaacaaa ttcgtcaatc gtaatattca gtttatccaa aagattaagc aagcgactgc
    37501 aggtgatttc tgattcccct cgttcaaatc ttgaaatttg tgacttggac aggtattcat
    37561 ctgctaaaaa agaaatgcta acctgcttac ccttacgtaa tcgccttaag gtttttccga
    37621 gttctttttc catttttccc actttcacaa caaaaaatta aaatctgcta aatccattat
    37681 ataatacaag tacaaaatag aaaatcagaa aggagacagt catgaaaaaa gttaataaag
    37741 ctttgctttt tacattgatc atggatatcc tgattatcgt tggtggataa cctttcgctt
    37801 aaaaacaatc cacttttggg aaatccttat atttagtttg taacaggaaa actaatagat
    37861 attaaaaaga gtgttagcga cctagcggca gctttgacca gcaacgacct ggtgccactc
    37921 tcgacgaatg aggtgattat tatggaaccc ttacttcatt tacttcccaa agtcgtacca
    37981 gtacttatac acttggtaga caaagccaac gtatcatggt taacagtgat attacagtta
    38041 cctatactct taaagacaat ttggtagccc ttcataagga atataaaacc tttgtcaaaa
    38101 aaatattaca gataaaccga tcaccagtga ctacgacaag gctaaggtta tttataacca
    38161 tttaatcaac gaatacactt acgccacaaa ataacttagc accaatcgca aaaccgtaag
    38221 cagcatcaac aatcatactc ctaaagctct ttatcgtggc aagtgtggtg cttgtcaagc
    38281 ttatgccgtc atgtttaaag atatggcaga agctgcaggc ttatcaactt ggtatgtgat
    38341 aaaaaaggat tgaatgagca ccatgcttga aacatcgtta ccattcatgg tgttaattcc
    38401 tacgttgatg ctacctggaa tgattcagca tacaccacaa ggtatttcct tgctggaaaa
    38461 gacgtgagga atactgagta ccgtttagat agccagtaca accacttggc taatgctatt
    38521 ttaaatacca gctaccaaaa aggctaaact aacaacaact acatttttca actagaaagg
    38581 cctaaacaat gaccaaaaaa cagttttatc ttatcttagc tattagcata ctgtgtttta
    38641 ttcttgccgt cagccctaaa ccaccaattc ctaaacacac tattgaaagg aaaaggactg
    38701 cgatgaccat aggccactca aaacaaaacc ctcacaaaaa agaagccctt aaacacaaaa
    38761 aaaataaaaa taaggctcta tttcttccaa gtggggacag cgctatcaaa tctgttatta
    38821 gcatgacagt tagactcctg ttagatgacc aatcttagct ctcctaaaat cagtggacac
    38881 taccgtttcg gtagtgttct tttttaagct aaaaaactga tcatgaaaga gcaaccccat
    38941 caccctaaca gcccacttta cccgcacttt cttaaaaagt taggagaaaa cgatatacca
    39001 attattttct gatcccagct ccctatcatt aacaagatgt gtagcacgga cctacataca
    39061 ggtaagctag agtcattctc gctatttcgg acaaaaaggg gccggtagtt ccctgacctc
    39121 ttctttattt atcttgtaac actcctcttc ttagcgagac ttactagcac ataattctta
    39181 agcactctta tcatttagac taggaataac accatctgaa tgaagcaaat gatgcgtcag
    39241 atctgccaga gtatcatctc cataagtaat ccctgtttgg tgctgtttct gatgaaaatc
    39301 agatgactcc ttaactttag cagtcacctg ctggtcactt ggatgaaaat taatttctct
    39361 cttggcttca gccgcaactg gctcgaggaa caacttattg acattacggt cttcctccaa
    39421 atgattaagg atagcagcat catcttctaa cgaaagaacc ttcttgggta acaaaaaggg
    39481 gttatttagc cttggctcag taacgacttc cttggctact cgtgatagtt tattattgtc
    39541 ttcctcaggt atcaaacggt taggcaatcg atgcaattct tccggctgtg aggcgctcac
    39601 agctacttca gaagaaacct ccaagccctt tcctgtttgc ttgtctaaag caaccggcaa
    39661 tttattaact aactttttaa cctgtcctca gcgctcattt caacactagg aagagctgtc
    39721 gctggttcta gccagctacc aacttctgct ggtcttacct taacatcgct ggcaggcttc
    39781 tccttctcat cttgattagg tctaaaaggc tcaaaccgcc ctgttgattt ttcatctatg
    39841 acctttatat tgtcttttac tacatgagac agcggttcga catttaccat agcttcatgc
    39901 tcgttaaggc tctggtctcg tttgaattta ccaggaatac caggagtcgg tgtcccgaca
    39961 gattgatcgg cttcagtagg ctcttttacg gagccttttt tccataaaac tgctggagga
    40021 ataatatccg tagagccgtc cccataagta atcgtggcct gccccccctt tgaattaata
    40081 gatactttaa tattgtctgg gaaagcccca ctacctcctg tggttaaaag ggcacccgca
    40141 tttttaatga gagttgtcat tcgttcaata ccagcaacgc caatatggtt caagtcatct
    40201 actggtaact gatcaacaga tttcatggtg tatttccaag cttgcggttg aacaagaaaa
    40261 acagttccct tatacattgt gttatgcata tcatcaatga ctttgaaata ccttgtatat
    40321 ttggtttgta cattagggtt agcaacggga acagtgcttt caggaactcc tgacatcgta
    40381 aaaatccctc tagcagaagt ttgaaagccc tcataaacat gacccatacc aggaacagtc
    40441 tgagcggtca aagacttacc agaaccatcc aaagcaatgc gaatatcttt catcagatac
    40501 atctgattgg tgtaggtaaa cctaaccgtg ttagcctcat ctcgatataa aaccacttga
    40561 taaggctgat ccgacgagaa catctgtgtc ttttcttccc gataacctat cccaaagcct
    40621 ctactcgaag cacttactga atccgttgca acagaaaaac caatccctac tactagagca
    40681 atagcacctc taactaataa acgactcatt ccaacattaa catcttttaa catcatcatg
    40741 ttcctttcat tattttttta tttaggagtt catcatacta tattttctca aaaaagtcga
    40801 ataaataact ctattattga taaaaattat ataaaaaaac gaactttatt tataaaaaaa
    40861 taaaaaacat cattttgtta attagaaaac gaacaacaaa agagccgaaa ggctctttta
    40921 aactgtcagt aatgattagt cactcaaact tattagttag aataaatcaa gcaaaaatac
    40981 tagaaaataa aaaatataag gcaaactatt ccaaacaata tgcacgccaa tcgaataata
    41041 aatggatttt gtatagtggt acaaactagc gaaaatcaaa cctataccaa aatagacaac
    41101 aaagtcaatg atggacaaac catgcaagtg agactagcta aatagtatag aagataagat
    41161 cacaaccaag ggaccactca gcgagttccc aaatgttctc atgacaaaca acctgaacgt
    41221 tatctcttcg taaattgggg caaaaagaca gatagtcaat agtaaaacca ctcgaaagta
    41281 gtgattgacc tgattcatat cagttatcaa tcactactgg ttctgcgtta ttgggaaaaa
    41341 tgttttgact agcagggccc aacaaaataa aacgataaag gcaccgattg caaataggca
    41401 tttttgagct tagatggtga cccttgctag ttactgattg gctcagtttt tgttagcaca
    41461 taactcaaca gaaacaccac taactataag attaatacca atccatatac tccatctcca
    41521 ctctaaccct attgatagta aactaagcac ccaatgccca ggcaattgtt attattgtgt
    41581 tgttgcaact ttggcaaaga tgagtatagc aggatagaaa acagattatt tctgaaactt
    41641 caaaggtatc ttcttgtcac gaactattct ttaattgaat cggttacact aaactagccc
    41701 cattatttaa aaacaaactt taaatattat tcatttcgct ttttaagttt attaaatata
    41761 gagtgattag gagaaataag acgacctaat gataaaatca ttcctattgt atagcaaaca
    41821 acaataaggt gtaaataaaa ataaattgat acctctgata tactcgtcaa acatcctatt
    41881 attataataa aaacaattaa ggtaggaata agaatagtac acttaataaa taaccaaaat
    41941 tgcttaacaa cttgatacca tgtgagcact tctgtcgttt gtctttgttt gtagacaaaa
    42001 acgaataaat caaggataaa actccaacag ataagttgta tatttttcat taatggtaaa
    42061 tcgtagaaac tacctatact aaatagaatc actgcagaaa taataataat acctaaaaat
    42121 cttaatatat tacgcatatc ttcacctcct ctactctatc ggtagcaaat ataaccgaac
    42181 aaattgttat tcctgttatc agagacagtt ataacttttt taaccaattt tcaatacgca
    42241 ttgtgctttt aactctttag tctctaaagt taaatatctt aagtactgat attgtataag
    42301 tcatccattt tccccttaaa tgtgattgca ttatagctca gtagaattaa tcttaatttc
    42361 tggtattttt ttccatacca agtatctata acgcaaatat agataaacaa taagtataaa
    42421 ataaataaag atcacaataa gggatatacc tcctagtaca gcagcccaaa taggataagg
    42481 gtgcctaaag ttgtaggcta cactcaagat gataagggta aaagggacaa tgtaacctcc
    42541 cagcttttca acattttcta gaaatatcat ctttctatca gatagattaa aaataatatc
    42601 taaagttttc ataccactcc tctactactt atacatcagt gatagatagt catttatata
    42661 tttagtgagg ccagataata tttgtagcag caccagctgc tccacacaaa atataacctt
    42721 gccaagggat aaatacgcct gtctgagcac aaactgtcac tccctgcgca gcacctgcca
    42781 tccctgtcaa aaagatattt gctccgtctt ttccgcctcc atttatgata gccagaccat
    42841 tttttagcac ttccatattt ttgaagtctt tttcatttta atttcactct tttgtatttt
    42901 aaaaagctaa gagtgatatc taaattcatt ggcataatca ctattttctt ttatcgataa
    42961 aaacaaataa tgacgctacc aaagctacga tagataacat gtttaccgat ttttccgaaa
    43021 gggataattg attgaaaatt aaaaacacta aatatggtat agatttatca acattttttt
    43081 atgaatggca tcaacaatca ttaaaaacat tatagacgca tgcataataa taaaaatcgt
    43141 atagatcatt taatttgctg tatatcccaa atatgctcca ccaactgtaa atcctacaac
    43201 acatccacct gtcaatactg gatgtggcag tttacaaaat ttcaatccag aagctaagcc
    43261 tccaagacca ccaattacag catctcctgg agcgtttcct ccacttatac tagccatgtc
    43321 attaattgtt aattccttca ttgttgtcat cctttctttc ctctagaagc cgcctgtagc
    43381 tcctgttaca ccagcccaaa gagtaatagc tgttttagct ccaatataac cacaggctac
    43441 accgcaaact ggaaaaccta tagcagctcc agcactacct gcagcgataa ccccactgac
    43501 atttgcctgc caattattct taccaccctc aaccttggca agcttttcta tagtcatttg
    43561 gtgaaatgtt tccagtttct ttatctccat atcgaataac ttcttttcat aattcttaaa
    43621 tttgtctcgt tgcaacctcg agctagtaca gaatatcata aagaacagta tcatggtttc
    43681 aaaatcttaa aaggctgttt ttcatcatga aatgtctttt tatcctctct acacttacgc
    43741 tgtgacaata gttaattaat taagaagttt aaataatacc attcatgctt ttataaatac
    43801 cttttaagat ttttga
//
LOCUS       DAUGSW010000013        39073 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUGSW010000013 DAUGSW010000000
VERSION     DAUGSW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39073
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.013"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..1423
                     /locus_tag="VIB18_000807"
     CDS             <1..1423
                     /locus_tag="VIB18_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8765830.1"
                     /translation="LLLTVILYANSLNLPLKFISLLFVVSTLLIVFLPKKLEVATIIF
                     ILVFGTISAIISPINDIPDEYVHYSRTVYISEGDINLTNNNKKLRISKDVDKLIKQSG
                     KTFITSNLKATKHSTREYSYPYIKGTNAYYSFSYIPQALGILVGNALDLPILLTYYFG
                     RLCNLISYAMLAFIAIKLSGSFKQVIAVVTLLPMNIYLAASFNQDGFAIGLVLVTIGL
                     FINLLSSKDKSNYNTKFFLYLVLCGLLVLSKFTYFLLVCLPLFIPNEKFGKNTKLVIL
                     KKLGGLLLIFLFAAMWFRLYGQVKTPYVADFLKEVNVSQQVKNMLESPIVYSSIIIRH
                     MVINLINMNNIFQFGALSYGITNLFPLYVCFFFFVYISNATKITINIVEKMGIIFVIS
                     AIIGATVLAMYLTWTPVGSSTVLGVQSRYLIGIIPLVLLLFSSQQQKFKQIEDILSDK
                     LAIHISLLFILAMLMSTIFRYYH"
     gene            1517..2740
                     /gene="pepT"
                     /locus_tag="VIB18_000808"
     CDS             1517..2740
                     /gene="pepT"
                     /locus_tag="VIB18_000808"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEQ8765831.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDSYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            2781..3269
                     /locus_tag="VIB18_000809"
     CDS             2781..3269
                     /locus_tag="VIB18_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEQ8765832.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(3256..3453)
                     /locus_tag="VIB18_000810"
     CDS             complement(3256..3453)
                     /locus_tag="VIB18_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEQ8765833.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            3502..3978
                     /locus_tag="VIB18_000811"
     CDS             3502..3978
                     /locus_tag="VIB18_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8765834.1"
                     /translation="MAKEPWEEKNVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMIQGYWYANPGDQVTIK"
     gene            3993..4673
                     /locus_tag="VIB18_000812"
     CDS             3993..4673
                     /locus_tag="VIB18_000812"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEQ8765835.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    4697..4820
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4835..5365
                     /gene="infC"
                     /locus_tag="VIB18_000813"
     CDS             4835..5365
                     /gene="infC"
                     /locus_tag="VIB18_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEQ8765836.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            5407..5604
                     /gene="rpmI"
                     /locus_tag="VIB18_000814"
     CDS             5407..5604
                     /gene="rpmI"
                     /locus_tag="VIB18_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEQ8765837.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            5663..6022
                     /gene="rplT"
                     /locus_tag="VIB18_000815"
     CDS             5663..6022
                     /gene="rplT"
                     /locus_tag="VIB18_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEQ8765838.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(6313..8523)
                     /locus_tag="VIB18_000816"
     CDS             complement(6313..8523)
                     /locus_tag="VIB18_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEQ8765839.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIA
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPKNRE"
     gene            8631..9794
                     /locus_tag="VIB18_000817"
     CDS             8631..9794
                     /locus_tag="VIB18_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEQ8765840.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            9791..10477
                     /locus_tag="VIB18_000818"
     CDS             9791..10477
                     /locus_tag="VIB18_000818"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEQ8765841.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            10571..11737
                     /gene="aroC"
                     /locus_tag="VIB18_000819"
     CDS             10571..11737
                     /gene="aroC"
                     /locus_tag="VIB18_000819"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEQ8765842.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            11798..12139
                     /locus_tag="VIB18_000820"
     CDS             11798..12139
                     /locus_tag="VIB18_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEQ8765843.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASARELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            12360..13712
                     /gene="gorA"
                     /locus_tag="VIB18_000821"
     CDS             12360..13712
                     /gene="gorA"
                     /locus_tag="VIB18_000821"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEQ8765844.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGICVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFSEKTFDFKQLKANRQAYIDRIHASYERG
                     FDQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEM
                     AVNGPRLHPHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFGLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKIYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(13800..15068)
                     /locus_tag="VIB18_000822"
     CDS             complement(13800..15068)
                     /locus_tag="VIB18_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8765845.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(15098..15538)
                     /locus_tag="VIB18_000823"
     CDS             complement(15098..15538)
                     /locus_tag="VIB18_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765846.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITISRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTAPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTNP"
     gene            15773..16915
                     /locus_tag="VIB18_000824"
     CDS             15773..16915
                     /locus_tag="VIB18_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8765847.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTIIISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            16927..18141
                     /gene="thiI"
                     /locus_tag="VIB18_000825"
     CDS             16927..18141
                     /gene="thiI"
                     /locus_tag="VIB18_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEQ8765848.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            18278..19471
                     /locus_tag="VIB18_000826"
     CDS             18278..19471
                     /locus_tag="VIB18_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEQ8765849.1"
                     /translation="MIKTMQYKKTMATVVALIVALLLFGLIYDLLGVQKNKLAAQKSA
                     QPKVKTARVVANGDILIHDILYMSARKADDTYDFTPYFEYVKDWISGADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGI
                     DSIGIYDKDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKI
                     KKELQLAEKKADVTIVMPQMGTEYALEPTAEQKELYHKMIDWGADVVLGGHPHVIEPS
                     ETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAH
                     PTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKGGKYHDKIDEETKAKVALAYQEINDL
                     VNLKW"
     misc_feature    19576..19650
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            19685..19999
                     /gene="rplU"
                     /locus_tag="VIB18_000827"
     CDS             19685..19999
                     /gene="rplU"
                     /locus_tag="VIB18_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEQ8765850.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            20011..20337
                     /locus_tag="VIB18_000828"
     CDS             20011..20337
                     /locus_tag="VIB18_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEQ8765851.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            20365..20658
                     /gene="rpmA"
                     /locus_tag="VIB18_000829"
     CDS             20365..20658
                     /gene="rpmA"
                     /locus_tag="VIB18_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEQ8765852.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            20996..21910
                     /locus_tag="VIB18_000830"
     CDS             20996..21910
                     /locus_tag="VIB18_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8765853.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            21907..22365
                     /locus_tag="VIB18_000831"
     CDS             21907..22365
                     /locus_tag="VIB18_000831"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEQ8765854.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            22355..23245
                     /locus_tag="VIB18_000832"
     CDS             22355..23245
                     /locus_tag="VIB18_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8765855.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            23543..24676
                     /locus_tag="VIB18_000833"
     CDS             23543..24676
                     /locus_tag="VIB18_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="HEQ8765856.1"
                     /translation="MIDFIISIDDCAVELDSRQSWKIRYPLSTILFLVFVCQLAGIET
                     WKEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQSLTSLD
                     AVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLR
                     TIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEE
                     LQENAQYYQTVEKSRGQIEVRECWVSSDIKWLCQNHPKWNKLRGIGMTRNTIDKDGQL
                     SQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNLI
                     RKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG"
     gene            24965..25486
                     /gene="pyrR"
                     /locus_tag="VIB18_000834"
     CDS             24965..25486
                     /gene="pyrR"
                     /locus_tag="VIB18_000834"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEQ8765857.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            25502..26761
                     /locus_tag="VIB18_000835"
     CDS             25502..26761
                     /locus_tag="VIB18_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEQ8765858.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPILLGLLVGYVVALLVGVFTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLSEK"
     gene            26822..27757
                     /locus_tag="VIB18_000836"
     CDS             26822..27757
                     /locus_tag="VIB18_000836"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEQ8765859.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            27801..28883
                     /gene="carA"
                     /locus_tag="VIB18_000837"
     CDS             27801..28883
                     /gene="carA"
                     /locus_tag="VIB18_000837"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEQ8765860.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            29129..32305
                     /gene="carB"
                     /locus_tag="VIB18_000838"
     CDS             29129..32305
                     /gene="carB"
                     /locus_tag="VIB18_000838"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEQ8765861.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGICHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            32512..33783
                     /locus_tag="VIB18_000839"
     CDS             32512..33783
                     /locus_tag="VIB18_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8765862.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTTDI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGVAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            33783..34493
                     /locus_tag="VIB18_000840"
     CDS             33783..34493
                     /locus_tag="VIB18_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765863.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            34505..35725
                     /locus_tag="VIB18_000841"
     CDS             34505..35725
                     /locus_tag="VIB18_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8765864.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            35979..37712
                     /locus_tag="VIB18_000842"
     CDS             35979..37712
                     /locus_tag="VIB18_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEQ8765865.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVVSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            37839..38111
                     /gene="rpsP"
                     /locus_tag="VIB18_000843"
     CDS             37839..38111
                     /gene="rpsP"
                     /locus_tag="VIB18_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEQ8765866.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            38121..38360
                     /locus_tag="VIB18_000844"
     CDS             38121..38360
                     /locus_tag="VIB18_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEQ8765867.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
BASE COUNT        12419 a         6448 c         8051 g        12155 t
ORIGIN      
        1 attacttttg acagttattt tatatgccaa tagtttaaat ctacctttaa aatttattag
       61 tcttcttttt gtggtgagca ctttactgat agtgttttta ccaaaaaagt tagaggttgc
      121 tacgatcatt tttattttag tatttggaac gatatctgct atcatatcac ctataaatga
      181 tattcctgat gaatatgttc attattcaag gacagtttat atctcagaag gtgatattaa
      241 tcttaccaac aataacaaaa agttaagaat atccaaagat gttgataagc ttattaaaca
      301 gtcaggaaaa acatttataa catcaaactt gaaagcaact aaacacagca caagagagta
      361 tagctatcct tacatcaaag gaactaatgc atattatagt ttttcttata taccacaagc
      421 tttgggtatt ttagtaggaa atgcgttgga tttacctata cttttaacat attatttcgg
      481 aagattgtgc aaccttatta gctacgctat gcttgctttt atagctatca agttgtctgg
      541 ttcttttaaa caagtgatag ctgttgttac tttactacct atgaacattt atttagcagc
      601 atcttttaat caagacggct ttgctatcgg tttagtttta gtaacaattg gattgtttat
      661 taacttgctc tcatcaaaag ataaatctaa ctataatacc aaattcttcc tttatttagt
      721 tctatgtggg ttactagttc tttcaaaatt cacatacttt ttattagtat gccttccatt
      781 atttattcct aatgaaaaat tcggaaaaaa taccaagtta gtcatcttga aaaaattggg
      841 aggactatta ctcatttttc tttttgctgc aatgtggttt agactttatg gacaggttaa
      901 aaccccatat gtcgcggatt ttctaaaaga agtaaacgtt agccagcaag ttaaaaatat
      961 gctagaatcc cctatagtct atagcagtat tattattaga catatggtaa ttaatctgat
     1021 taatatgaat aatatttttc agtttggcgc attaagctat ggcataacga acctattccc
     1081 gctttatgtg tgtttcttct tttttgttta tattagtaat gctactaaaa taactattaa
     1141 tattgtagaa aaaatgggta taatctttgt tatttcagcg attataggtg caactgtatt
     1201 agctatgtac ctgacttgga caccagtagg gtcctcaact gtattaggtg ttcaaagtcg
     1261 ttatctgata ggaattatcc cattagtgtt gcttcttttt agtagtcaac agcaaaagtt
     1321 caaacaaata gaggatatcc tttctgacaa actggctatt catatttcgc ttttgtttat
     1381 tctcgcaatg ttaatgagta ctatttttag atattatcat taaactctta attagaggct
     1441 ttaaaaaact tagcttgaat aagtatttta aagcctttta tgctataatt aaattgagaa
     1501 attattgagg tggcctatga agtacgataa cttgttagat cgatttataa aatatgtcaa
     1561 agtgaataca agaagcgatc cagacagtga gactactcct agtacggaga gtcaagaagc
     1621 atttgcctta acgattttaa agcctgaaat ggaggcaatt ggtttgcaag atgttcatta
     1681 taatccagtt aatggctatc ttattggaac tctgcctgcc aataatccaa ccttgacgcg
     1741 taaaattggt tttatagccc atatggatac ggctgatttc aatgctgaaa atgttaatcc
     1801 gcagattatt gacagttatc aaggagggga cattacactt ggcagttcta attataagtt
     1861 ggatccaaaa gcatttccaa atcttaataa ttatatcggt caaacattga ttaccactga
     1921 tgggactaca cttttagggg cagatgataa atctggtatt gctgaaatca tgacagcaat
     1981 agaattcttg acatcacaac cacaaataga gcactgtgac attaaagtgg cttttggccc
     2041 tgatgaagag attggggtcg gagctgataa gtttgaggtg gctgattttg aggtggattt
     2101 tgcttatact atggatggcg gtcctttagg cgaattgcaa tatgaaactt tcagcgctgc
     2161 agctctagaa gtgacttttt taggcagaaa tgttcatcct ggtacggcta aggatcaaat
     2221 gattaatgcc cttcagttag caatagattt tcatgagaag ctacctgcta aagagcgacc
     2281 tgaatacaca gatggttatc aaggcttcta tcacttaacc ggactaactg gaacagttga
     2341 agaggcacgc gcatcttaca ttattcgtga ttttgaagaa gcatcatttg aagctagaaa
     2401 agtgaaagtt gaaaatatag ctcaatcgat gaatgctcag ctaggaacaa aacgtgtctt
     2461 ggtagagctt aatgaccaat actacaatat gaaaaaagtt atcgaaaaag atatgactgc
     2521 tattgagtta gctaaagaag taatggaaga gcttgctatc aagcctgtaa tcgaacccat
     2581 acgtggagga acagatggct ctaaaatttc atttatgggt attcccactc ctaatatttt
     2641 tgcagggggt gagaatatgc acgggcgttt tgagtttgtt agcttacaaa cgatggagag
     2701 agctgtcgat gtcattattg gacttgtttg caaagcctaa ttatcatgta attgatattt
     2761 agtggaaggg acttataaaa atgattaaac tatttggtaa aataaggtat cactggcagc
     2821 cagagttgtc ttggtctatt atttattggt ctattgcgtt tgcacctatt tttgtaggtt
     2881 tatctttgtt gtatgagcgc actgaaatac ctagtcgggt ttttattcta tttgctattt
     2941 ttgctgtcct agttggcatt ggattacatc gttatttcat tattgaaaat aatggtattt
     3001 taagaatcgt atcttttaaa ttgtttggtc cacgtaagct acttatttct actattacta
     3061 agattgaggt gaccaaatca acactttgtc tgcacgttga agataaaagt tatctctttt
     3121 atatgcgcaa atggcctaaa aaatattttc ttgatgcctt agcggttaat ccatacttcc
     3181 aaggagaagt tatattaagt gataacttta ttaaattaga ctattttgaa gtttatcagc
     3241 atgataaaaa agcccttact cgagggtaag agctttagtt gggcaagatt tgacagctaa
     3301 aatagcgtcc ttatctgaag gacaaattga ctgacttgtt tcagatgagc ttgaaaatgt
     3361 gacgatacca ttgtcatgat aatcaaaaag tgatgaatag gtttggcata gaccacaagc
     3421 gatgcatttt tctggaatga tagatacttt cataactatt attctaatat gattttgtta
     3481 aattaacaag gggggacgat catggctaaa gaaccatggg aagaaaaaaa tgttgatgat
     3541 actataggga cacgaacacg taaatcaaga aatgctttca ttagcacgcc ttggttgact
     3601 gctttattaa gtgtattctt tgtcatcatt gttgctatac tttttatttt cttttataca
     3661 tcaaatagcg gtagtaatag acaagctgaa acaaatggtt tttatggagc atccactcat
     3721 aaaaaaacaa ggaaagcttc taacgctaaa aaaacatcaa gtagttcaac aactacagac
     3781 acaacacctt ctagcgaaga aacacttgct tctagtgaag gaactggcga aacccttact
     3841 gtattggcag gtgagggggc agcttctatt gcagcccgtg caggtatttc tgtggagcag
     3901 ttacaagcac ttaatccaga gcacatgatt caaggatatt ggtatgccaa tccaggagat
     3961 caagtcacta ttaaataatt gaagaggaaa aaatgaaagc aattaaaatt gcgattgatg
     4021 ggccagcttc aagtggaaaa agtacagtag ccaagattat tgcaaaaaat cttggctata
     4081 cttatctaga tactggtgct atgtatcgct cagcaactta tatcgcactg acacatggct
     4141 atacgggtaa agaagtagcc cttattttag aggaacttga gaaaaatcct atttccttta
     4201 aaaaagcaaa agatggctcc caattagttt ttcttgggga tgaggacgtg accttagcca
     4261 ttaggcaaaa tgatgtaact aacaatgttt cttgggtctc agctttgcca gaaattagag
     4321 aagagctggt tcatcaacaa agacgcattg cacaagctgg tggcattatc atggatggtc
     4381 gtgacattgg aacggttgtt ctcccagatg cggaactaaa aatcttttta gtggcttctg
     4441 tcgaagagcg ggcagagcgt cgctataaag aaaacctaga aaaaggaatt gaatcagatt
     4501 ttgagacgct aaaagaagag attgcagctc gtgattacaa ggatagtcat cgtaaggttt
     4561 cacctctaaa agcagctgaa gatgccctta tttttgatac cacaggtgtt tctattgatg
     4621 gcgtggtgca atttatccaa gaaaaagcag aaaaaatagt tgacatgtcc tagagcctat
     4681 gttagaatag taacaatgag aaaagtagaa gtgagagctt ctcgccttgc gacttaggtt
     4741 gtctggccct aacatgtcaa attcctatgg aatattatgt gtgcgggctt gatttatcaa
     4801 gtccgctttc gtttttctct aaaaaaataa agaggtgaag atcatagcta aaaaggatct
     4861 attcattaat gatgaaattc gcgttcgcga agttcgtctc gttggtcttg aaggtgaaca
     4921 attaggtatt aaaccattgt ctgaagcgca atcattggct gatgcttcaa atgttgattt
     4981 ggttttaatc cagccacaag ctgttcctcc tgttgccaaa cttatggact atggaaagtt
     5041 caaatttgag tatcaaaaga aacagaaaga acaacgtaaa aaacaaagcg ttgtgactgt
     5101 gaaagaagtt cgtctcagtc cagttatcga taaaggtgac tttgaaacaa aacttcgtaa
     5161 cggtcgtaaa ttccttgaaa aaggaaataa agttaaggtt tctattcgtt tcaaaggacg
     5221 tatgattact cataaagaga ttggtgccaa ggtactagct gactttgctg aagcgactca
     5281 agatattgct atcattgagc aacgagcaaa aatggatgga cgccaaatgt ttatgcaact
     5341 tgcaccaatt tcagacaaga agtaattgtc acagtttcat tatatcttta agaggagaat
     5401 actaaaatgc caaaacaaaa aacacaccgc gcatcagcta aacgttttaa acgtacaggt
     5461 tcaggcggtt tgaaacgctt ccgcgccttt acatcacacc gtttccacgg aaaaactaaa
     5521 aaacaacgtc gtcatcttcg taaagctggt ttggttagct caggagattt caaacgtatc
     5581 aaagcaatgg ttactggtct ttaattttaa aggcagtaga catttacgag tattataaga
     5641 attatttgaa ggagaactat taatggcacg tgttaaaggt ggcgttgttt cacgcaaacg
     5701 tcgtaaacgt attttaaaat tagctaaagg ttactatgga gcaaaacaca tcttgttccg
     5761 tactgcaaaa gagcaagtga tgaactctta ctactatgca taccgtgatc gccgtcagaa
     5821 aaaacgtgat ttccgtaaac tatggatcac tcgtatcaat gcggctgctc gtatgaacgg
     5881 tttgtcatac tcacaattga tgcacggttt gaaacttgct gaaatcgaag taaaccgtaa
     5941 aatgcttgct gatttagcag tagctgatgc agcagctttc acagctcttg ctgatgcagc
     6001 caaagcaaaa cttggcaaat aagaaacgct atacctaaaa aataactttc tattacctat
     6061 agaaagttat aaagaaacaa aaatgaagga gacgatggac gtcttctttt tattatactc
     6121 aatataataa aaaatagttt cccatgtttt attaccagta atgtgggata tttagatggt
     6181 agcaagaagt tttatagctg atttgttttc tttaggtcta attagcatat tttgattact
     6241 gataaacttg aatatcgcca ataaaaaaga agcaaaatta ttattttgct tctagtcaga
     6301 tcattaaatt gattattctc tatttttggg gttatcctct tttagttcag aagttgccgc
     6361 gtcagcttct acgggattta gttctaagta agatggtgct ttaaaaagtt tctgagttga
     6421 tttatgacca tttttactgt ataaacttgt tgactctgat ccgagttttg ctgaaatatc
     6481 tttcagttgt tttaactgct tagtgtagat aaactggtta ggatcaatag cttttagacc
     6541 attttgagta tcaaagcgca ggagatcacc cgtttgaata gcgtcgctag ctgctagttg
     6601 ttgagcaaca gcagagcgaa tttccttagt tttggctata gtcatttcat cgggattagt
     6661 gatttctaaa cctgtttgcg tgttgtacag acgtccacta tagttagtgt attcaggagt
     6721 catataagtc ccagatgttc gttgtgccac aatctggcta ttttgaggtg ataataaatc
     6781 ttgtcctaat tgaacaaact gactagtgtc aataccaagt atgtggagta aagtaggaag
     6841 agcatcgatt tcaccgccaa aggtttcttt gatactacca ttcgtataac ctggaatatg
     6901 gatcatatac gggactcgtt gtagcatagc attatcatat tcagaccaag tttcagaatc
     6961 tttaccaaga agtggagcaa gactagaatt acgagaattt gaaataccat aatggtcacc
     7021 atataaaaca aaaatagaat tgtcgtacaa accagtggct ttcaagtaat caaaaaaaga
     7081 tttaagggca gcgtctaaat aattggcagt agcaaagtaa ccattgatcg tttcatcgtc
     7141 tgttttggct aaaggaaaac cttcttcact actttcgcct tttagactag tataaggata
     7201 gtgattactc acagtgataa acttggtata aaaaggttgt tgcatctgtt caagatattt
     7261 tatggaatcc ttaaacatgt acttatcatt taacccatat tgaaaagagt tcttactatt
     7321 ttgtttagag aagtagctag aatcaaaaaa ataattatag ccccattgtt tataagcatt
     7381 attgcgattc cagaaagttc caacgttacc atgaaagaca gcgctggtat agccaccttt
     7441 ttgggctaaa atacttggag tagcaaattg tgtattttca ccaccgtagt tcaccataaa
     7501 agaaccacta tttaaaccaa ataaggaatt ctccatcatg gtttcagcat cagaagtttt
     7561 acctgcttta acctgatgaa aaaagttagg gaatgctaag gtagcatttg agtgataaag
     7621 cgagttgata aaaggcgtta cctcatattc tttatctcct tcttttagtt tataatctat
     7681 taagaattgt tgaaagcttt ctaaatgaag aacaataata tttttgcctt ttccaattcc
     7741 aaaatactga ggatcaggtg ctgcataatg tcctttgaca taagttttaa catcaattaa
     7801 ttcttctgca gtagctccat ttcgttcttt ttgagcttga taggtttgat tgccgctata
     7861 gagggtaaac gctggtagtc ctaaagctct aacaatataa gtatttgaaa agccacgtgt
     7921 taatagttcc ggacgatcaa tttctgctaa aaaaagatta atagaaagca atagactaga
     7981 taaagcggtg atggcaaatg ctgcgcgctt gttaaaagga cgttggtcat ttttgatttt
     8041 tttagcgata gataaactaa ttagaataat aaaatcaaga atatagataa tatcccagat
     8101 gcgtaaaagg tttaaagcag agtcccctaa tccagcggag actttactac tagctagcat
     8161 ggcactcact gtaataaagt ctgaaaattc tcggtaatat atagaatttg atatcaagag
     8221 aatgttaagg ataatataaa ccacccaaga acagatataa aaggctcggg tattcttaac
     8281 gtaaagagca acccccaaaa gtaaaaaagc tagtgggatt ggattgataa tagttagaaa
     8341 gacttggtat atatttccca aatctagtga aaagtctgta tgatatgccc acagggtctt
     8401 tatccagtaa caaaagagta gagtaattat aaaacccaat cttgtgttga taaaacctgt
     8461 gataagtgtt ttaaatttct tcacagtagc aacttcctta tcgttttttc ctaaagatgt
     8521 catctccaaa taaaatctca gattaaatta taccaaaaat gtgaagctaa tgcttgttgt
     8581 aagttcaaat ttagtaggat tttttatcag attttgttat aataaaaact atgaataaac
     8641 tctatattga ttcttttgtc gaaaagaagc tgacagcagg ggtacaatta ttagatgaaa
     8701 aagatttttc taatataaag gaaaaaaatc agttggttca actggtgacc aagtccaatc
     8761 gtcccattgg aacagcatat atctctaagc aaaataaagg aattggttgg tatctaggac
     8821 cagaaaaaat cgacttgtct atctcttatt ttgttagtct attttcagtt gctaaggcca
     8881 aaagacaaga ttttgctcaa tcggacgaga ccaatgctta tcgccttttt aatcaagaag
     8941 gagacggttt tggtggagta acaattgatc tttataaaga ttttgcagtc ttttcatggt
     9001 ataatgcctt tgtctatgac aaaaaagaaa tgattatgga ggcttttcaa caggtttttc
     9061 ctgaagtcaa aggagcttat gaaaagtgtc gctttaaagg tccagatact gaaactgctc
     9121 atctgtatgg tgagctggca caagaaacct tttcgatttt agaaaatggc atagcctatc
     9181 aagtcttctt gaatgagggc ttaatgacag gtatttttct agaccagcat gatgttagaa
     9241 gagcactagt agatggttta gctatgggca agtcccttct taacctattt tcctatacag
     9301 ctgccttttc tgtagcagct gctatgggtg gtgctatcga gaccacttct gtggacttgg
     9361 ctaaacgatc gagagaatta tcactagctc attttgagca taaccagtta aacttagcct
     9421 cacatcattt tgtggtgatg gatgtttttg aatacttcaa atatgccaaa cggaaaaaat
     9481 taatctttga tgtgattgtg attgacccac caagctttgc tagaaataaa aaacaaactt
     9541 tctctgtgag cagggactac cacaaattaa tcacagaggc cttggacata ttgagtccta
     9601 agggaactat tatagcttca acaaatgctg ctaatatgac tgttagccag ttcaaaaagc
     9661 aaattatcaa aggatttgga agtcgtcgtc ctgagtctat gactctccag cagcttccga
     9721 gtgactttac tatcaataaa gcagatgaaa gaagtaacta tttaaaggta tttactataa
     9781 aggtacgaga atgagaattg tagcaccagt catgccaaga cattttgacg aggctcaagc
     9841 cattgatatt tctaaatatg aagatgttaa tttaattgaa tggcgagcag actttcttcc
     9901 caaggatgag attgtcgcag tagcaccagc tatttttgaa aaatttgccg gaaaagaaat
     9961 tatctttacc cttcggaccg ttcaagaagg ggggaatatt accctttcaa gtcaggagta
    10021 tgttgatatt atcaaagaga tcaatgctat ttataatcca gactatattg actttgagta
    10081 ttttacgcac aagtcagtat ttcaagaaat gcttgatttt ccaaatctta ttttgtctta
    10141 tcacaacttt gaagagactc ctgaaaattt aatggaagct ttttcagaaa tgaccaagtt
    10201 ggcaccgcgt gtggttaaaa ttgctgtgat gccccagagt gaacaagatg ttctagattt
    10261 gatgaactat accagaggct ttaagacgct caatcctgag caagaatttg caactatatc
    10321 tatggggaaa ttaggaagat tgtctcgttt tgcgggagat gtcattggct cttcctggac
    10381 atacgtttca ttagatcatg ttagcggtcc aggtcaagtg actctcaatg atatgaaacg
    10441 tattattgag gtcttagaaa tggatatatc taactagtga atggtctaaa aatattattt
    10501 ctacaatagt taagaaatga tgtttttaga ttaatgtttt taaaataagt ggaaccaaaa
    10561 aggagaaaaa ttgcgttatt taacagcagg agaatctcat gggccatcct taacagctat
    10621 tattgaaggt ataccagcag gattaactct tcatccagcg gatattgatc acgaattaca
    10681 gcgacgtcaa ggaggttatg gccgtggtgc cagaatgtct attgagactg atcgggttca
    10741 aatatcctca ggagttcgtc atggcaaaac aacaggggcc cccattacct taacggtaat
    10801 taataaggac caccaaaaat ggctagatgt catggctgta ggagacattg aagagactct
    10861 caagttaaag cgtcgtgtta agcatcctag accaggacat gcggatttgg taggaggtat
    10921 taaatatcat tttaacgatt taagagatgc cttagagcgt tcctcggcta gagaaacaac
    10981 gatgagagtg gctgtaggcg ctgttgctaa acgtatctta gctgaacttg gaattgatat
    11041 gttacatcat atcttaatat ttggtggtat aacgatcaca ataccttcta agctctcttt
    11101 tagagagctg caagaaaggg ctctccattc agaattatct attgttaatc caaagcaaga
    11161 agaagaaatt aaaacgtata ttgataagat aaaaaaagaa ggggatacta ttggtggtat
    11221 tatcgaaacg atagttcaag gggtgccagc aggtcttgga tcttatgtcc aatgggataa
    11281 aaaattagat gccaagctgg ctcaagcagt tctttccatt aatgctttta aaggggtgga
    11341 atttggagtt gggtttgata tgggattcca aaagggctct caggtaatgg atgaaatcac
    11401 ctggacacct acccagggct atggtcgtca aacaaaccac ttaggtggct ttgaaggtgg
    11461 catgaccaca ggacaacctc ttgttgttaa aggggttatg aagcccattc ctactttgta
    11521 taaaccactc atgtcggtag atattgatag tcatgaacct tataaagcaa cggtggaacg
    11581 ctctgatccg acggccttac cagctgcagg ggttatcatg gaaaatgtgg tggcgacggt
    11641 gcttgccaaa gagattttag agactttttc ttctactacc atgtctgaat tgcaaaaagc
    11701 tttttcggac tatcgtgcct acgtcaagca attttagata gcgagatact ggcttttatg
    11761 gtatcataca ggtattaatg aacaaaagga gactgtcatg tcacaagaaa tttatgacta
    11821 tgctaatcaa cttgaaagag cagttcgtgc tctgccagaa taccaaaaag tgttagaagt
    11881 aaaagaggcc attcaagcag acgctagtgc tagggaactg tttgatgagt ttgtcgctat
    11941 gcaagaaaaa atccaaggga tgatgcaatc aggccaaatg ccaacggctg aagaacaaac
    12001 aagcattcaa gaacttagcc aaaagattga agctaatgac cagctaaaag cttattttga
    12061 agcgcagcag gccttatctg tttacatgag tgatattgag cgtattgtat ttgctccgtt
    12121 gaaagattta gtcaagtaag ccaattaaga taggaaaaaa acagattgct ggcagctcgt
    12181 caggatctgt tttttagtgt ttattttctt tgtatcagaa agttgagcct ctttcttatt
    12241 tgtgatatag tcaaataaag tgaccaaaat agcaggccag tagtggcttt aatgaaggca
    12301 agttgtctgc taactggcta tgctaaaaca tcagtattag aaagtaaaag gtgataaaaa
    12361 tggttattcc ttatgattat attgttattg gtggagggag tgcaggtatt gcttctgcga
    12421 acagggcagc catgcatggg gccaaagtat tgttagctga aggtaaagag attgggggaa
    12481 tctgtgttaa cctaggctgc gttcccaaaa aagtcatgtg gtatggcgct caagtagcag
    12541 atattttagg gacttacgct aaggattatg gattcgactt ttcagagaaa acatttgatt
    12601 ttaaacaatt aaaagcaaac cgccaagctt atattgatcg gattcatgct tcttatgagc
    12661 gaggctttga ccagaatggt gttgaccgta tctatgacta tgctgttttt aaagatgctc
    12721 atactgtgga aatagcaggg cagctttata ccgcaccgca tattttgatt gccacaggag
    12781 gacatcctgt ttttccagat attgaggggg cacaatacgg tatcagctcg gacggctttt
    12841 ttgccttaga tgaggtacca aaacgtacgg ctgtggttgg ggcaggctat attgctgtgg
    12901 aacttgccgg tgttttgcat gctttgggat cgaagacgga tttgtttatc cgtcacgatc
    12961 gacctttaag aagttttgac aaaaccattg ttgatgtctt agttgatgaa atggcagtta
    13021 atgggccgcg tttacaccct cattcagaag tggcaaaggt tgtcaaaaat actgatgagt
    13081 ccttgaccct ttacctcaaa gatggccaag aagttgaggt tgaccagctc atttgggcta
    13141 tcggtcgcaa gcctaatcta gaaggttttg gtcttgacaa aactggagtg acgttaaatg
    13201 ataaaggtta tattgagaca gatgcctatg aaaacacgtc tgtcaaaggt atttatgccg
    13261 tgggagatgt taatgggaaa ctggctttaa ctccagttgc tgtggcagct ggacgtcgcc
    13321 tatcagagcg tcttttcaat ggcaaaacag acgagaaatt ggactaccaa aacgttgcta
    13381 ctgtgatttt tagtcaccct gttattggct ctgttggctt gtcagaagaa gcagcagtca
    13441 aacagtatgg gcaagaagca gttaaaatat atcaatcacg ttttacgtct atgtttactg
    13501 ctatcactaa ccatcgccaa ccttgtctga tgaagttggt aacagtcgga gataccgaaa
    13561 aaatagttgg tcttcacgga atcggctatg gggttgatga aatgattcag ggctttgcag
    13621 tagccatcaa aatgggagca accaaggcgg attttgataa caccgttgct attcacccaa
    13681 ctggctcaga agaatttgtc accatgcgct aaaaaatgta gcctaaggca ataaaaaatg
    13741 atgttaacag tttttgagga aagtcttcta aactgctagc atcgtttttt gttaggtgat
    13801 taggggaata tgtttttaaa gatatttgcg ttgctcagac aatattgcct tacctcggag
    13861 ataaaataaa gtgaccctgt aacaacaaag agttcatcag atgttacgga accttgtaac
    13921 cagtctctgt aatcttttac ctgtgggtat ttatcaggat aatcctctaa aagatttgct
    13981 tcagggaaat caaaagtcgt gacagatact tcaaaagtat ctagttgagc cagcaagtcg
    14041 gctaaaggct tacgtttgag acctgcaaag agaatatgaa taggacgttt gggaaattct
    14101 tcttgcagta gagactttaa tttagcaatg gaatctggat tgtgagcgcc gtctaataga
    14161 agattaggtt gaataaattc ggaccggcca ggccaagttg ttgcctcaat tcctttttga
    14221 atcgtttttg gagatatttt aggaaaggat tttctaagca attgagctgt cataatggct
    14281 aagcaggcat tcgctttttg atgttgacct aatagtttga gacggagttt ggttaaattc
    14341 aagttatcgt gttgaaagga aaacgtcttt tctgaaggat tgagcaaaaa atcttttcct
    14401 aattgatata agcgtgaacc ggctttttgg gtaacttgtt gaaagacttg actagcctcc
    14461 tgctcaagtt gaccgataat aacgggttct ttagctttga taacttctgc tttttggtga
    14521 gcaatttctg ctaggctata acctaaacgt tcttggtgat caaaactaat agaagggcat
    14581 acgacggcca gagcatgaaa aacattggtt gcgtcggttt ttccaccaat ccctgcctca
    14641 ataatggcaa tatcaacagg tttaagattg gcaaagtagc aaaacattat gagcgtcact
    14701 aactcaaact cggtaggtct atcccaattt gtttcaaggg acattttagt gagaatgggt
    14761 ctaatcacgc tcacacattg cgccaattct aggtctgaaa tgggctggcc attaaggcaa
    14821 atccgatcgt gaaaagagat aataaaagga gatgtaaagg ttccgacctg ataaccagaa
    14881 gttgacagga tatgctgtaa gtaggctgtc acagagccct tgccgttagt tccaacaacg
    14941 tgaatagcag ggaatttgtc ttgtggccgg cctagtgcct caagtaacca agccattctg
    15001 gccaaatcgg tcttgcgacc attagcctta aaggtatgaa tccaggaaat gctatcatag
    15061 gtagtcatta ctatttcttg tccttctaac aatgctttta agggttcgta ggaagaccag
    15121 tattagcatc ttcagctcca gttgcattag gaagttgcgt cccttcagtg gttgatggtg
    15181 tctcaggagc tgtaggagta gtctcgttgt gagaaggtgc ggtagaagat gacggaagag
    15241 ttgtcttatt atcatctgtg gtttctgaag tacctgtatg gttttgatta ccctgagaag
    15301 actctttttc aataatcttg acaatggtat tactcgattc tttgggtgta tcattagagg
    15361 tcttatctgg tacaggctgc agtgctcttg aaatggtaat ggttgccacg atgatactca
    15421 aaatactacc aataagtgca atggattttt ggaaagctgt aaaacctgtt ttaatatgct
    15481 cggtagggac acctcctgat ttacgaggtt tttgttgacg ggaataacgt gatgacatat
    15541 ttttctcctt taaaatcatc gtaatgccaa gattaaggag gaggaaacag aagtcctagc
    15601 tcctctttaa cacttcatct atcagtataa tctagaaaaa aagtgaagtc aacggtttac
    15661 cttatgtcta ggacaaggaa gtcctttggg cttattgtaa tacgaatatt cttgatttca
    15721 ttttagctat tttgtgatag aataaagtat tgagtaaaaa tgaaggtgac acatgattta
    15781 ttttgataat gcagccacaa ccatacctta tggagaggct cttaaaactt accaagaagt
    15841 agcaacaaaa atatatggca atccctcaag tctgcaccaa ttagggacaa atgcgtctcg
    15901 cattttagaa gcttcccgta aacagattgc tggtttgttg ggtgttaagt cagaagaaat
    15961 cttttttacg tctggtggga ctgaaagtgc taattgggct attaagggaa ttgcttttga
    16021 aaaaactgct tttggcaaac atattattat ctcagccatt gaacaccctg ccgtgagtga
    16081 aagtgtcaaa tggcttctca cacaaggatt cgaagtttct tatgctccag tgacaacaca
    16141 gggagttgtt gatgtgaatg ctttggctga gctgattaga ccagacacca tcataatctc
    16201 gattatggct gttaataatg aaatgggagc tatccaaccg attagagcca tttcaaacct
    16261 attggctaac caaccaacga tcacctttca cgttgatgct gttcaagcca ttggtaaaat
    16321 accactctgt gattatatga ctaatcgtgt ggatttggct tctttttcag ggcacaaatt
    16381 tcatagtgtt cgtggtgttg gcttccttta taaaaaagca ggcaagcgac tcaatcctct
    16441 cttgtcaggc ggcggccaag agcaggagtt acgttcaacc actgaaaatg ttgcaggaat
    16501 tgctagcatg gccaaagcat taagaatagt cactgaaaaa caagtgagcg tcttacctaa
    16561 actaacagca atgcgagatg tgatttacaa agctttgtcc gcttacccag atgtgacagt
    16621 attttcagct caagaaggct ttgcgcccaa tattttgacc tttgggatta gaggggttcg
    16681 aggagaagtt attgtccacg cctttgaaaa atatgagatt tatatttcga ccacaagtgc
    16741 atgttcgtcc aaagcaggta agccagcagg aagcctagtg gctatgggga ttcctgtaaa
    16801 aactgcccag acagccgttc gtattagtct agacgatgac aacgatatgg gacaagtaga
    16861 gcaatttttg accatattca aacagattta tgataaaaca cagaaagtta ggtaagatta
    16921 ggtaagatgg actattcaga aattatggtt cgccatggtg aactatcaac taaagggaag
    16981 aatcgcatgc gattcattaa caaacttaaa aacaatattc aagacgtact ggctcctttc
    17041 ccagccatta ctgtccgttc agatcgtgat aggacccatg tgtctctaaa tggcacagat
    17101 tatcagccta ttgtagaagc tttaaagctg gtgtttggtg ttcaagctct atctcctgtt
    17161 tataaacttg aaaaaagtgt ccctcttttg gtaacagctg ttcaagatat catgacttct
    17221 ctttatcgtg atggactgac gtttaagatt gccactaagc gtagtgatca cgcgtttgaa
    17281 ttggatagtc gtgagcttaa cagtcttctt ggtggagctg tttttgaggt tttaccaaat
    17341 atccaagccc agatgaaaca tcccgatgtg actctcaaag tcgaaattcg tgatgaagca
    17401 gcttacattt cttatgaaga gattaaggga gcaggcgggt taccggtagg aacgtcaggg
    17461 aaagggatgc tgatgttatc gggcggtatt gattcaccag tagctggcta tttagccctt
    17521 aaacgtggcc ttgatattga agttgttcat tttgctagcc ctccgtacac cagtccaggt
    17581 gccttggcta aagcccaaga ccttactcgt cgattaactc gttttggtgg aaatatccaa
    17641 tttatcgagg ttccttttac agaaattcaa gaagaaatta aaaataaggc accagaggct
    17701 taccttatga cattaacccg ccgctttatg atgcgcatca cagatgccat tcgtgagcaa
    17761 cgtaagggtc ttgttattgt taacggtgag agcctaggtc aggttgctag tcaaaccctt
    17821 gaaagcatgc aggccattaa tgcggtaaca tcaactccaa ttattagacc agtcgtgaca
    17881 atggataaac ttgaaattat cgagatggct caggcgattg atacttttga catttctatt
    17941 caaccgttcg aagattgctg tactattttt gcaccagacc gtcctaaaac caaccctaaa
    18001 ctaggtaatg ctgaaaaata tgaagaacgc tttgatattg atggtcttgt ccagcgtgct
    18061 gtgtcaggaa ttgttgtcac agaaatcaca cctgaaatcg tcaatgatga ggttgaaaat
    18121 ctcattgatg ctttacttta aaagaaaaga tcaagtgtaa atcttttagt agtcagtaat
    18181 gatactattg aaaagcctct ataagggctt ttttgctgca atgaagtagg aaaattttga
    18241 ggcaagatgt tataatagag aaaaaggagg gtgtgtcttg attaaaacta tgcaatacaa
    18301 aaaaacgatg gcaacagttg ttgctcttat cgtcgcactt ttgctatttg gcttgattta
    18361 tgatttactt ggggttcaaa aaaataagct agcagctcaa aaatctgctc agccaaaggt
    18421 caaaacagcg cgtgttgtag ctaatggcga cattttaatt catgatattc tctacatgag
    18481 tgctagaaaa gctgacgata cctatgattt cactccttat tttgaatatg ttaaggactg
    18541 gattagcggt gctgacttag ctattggaga ttatgaaggg accattagcc cagattatcc
    18601 cttagcaggc tatcccttat tcaatgctcc agaagagatt gcaggtgctc tgaaaaatac
    18661 tggctatgat gtagtcgatt tagcccataa tcatatctta gattcccaat tagacggtgc
    18721 ccttaacact aaaaaggttt ttcatcaatt aggtatagac agtattggca tctatgacaa
    18781 ggatcgttca aaagaatcct tcttaattaa aaatgtcaat ggtatcaaaa ttgcaatttt
    18841 aggttattct tatggttata acggcatgga ggccacactt agccaagaag actatgagaa
    18901 acacatgtct gatttagatg aagctaagat aaaaaaagaa cttcagctag ctgaaaaaaa
    18961 ggctgacgtg accattgtca tgccacaaat gggaacagaa tatgccttag aaccgacagc
    19021 agagcaaaaa gaactttacc acaaaatgat tgattgggga gctgacgtcg tcctaggagg
    19081 ccatccgcat gttattgaac cttcagagac agttataaaa ggtaggcaaa agaaattcat
    19141 tatttactct atgggaaatt ttatttcaaa tcagcggctt gaaaccgtag atgatatctg
    19201 gactgagcgt ggcctattga tggaccttac ttttgagaaa aaagataaca aaacaaaaat
    19261 taaaacagtt gaggcccatc caaccatggt tttagccaaa ggtaaaggca ttgtgggtaa
    19321 agaaggtttt gaactataca attatcgaac aatggtttta gaagatttta tcaaaggtgg
    19381 aaaataccac gacaagattg atgaggaaac caaagcaaaa gtagcacttg cttatcagga
    19441 aattaatgat ttagttaacc tgaaatggta atgtttggtg gtttagcatc taacgataaa
    19501 aaatagagat taaacttaat ttttccttga taaaaagcag ttatggtgct aaaatagtaa
    19561 cgttgactaa atgcacatcc tgtgcaaccg cgcgaaaatc gttgtcaagt agaccaagtc
    19621 tcacgattcc aggcgagtct tcacagaggg aaacctcaaa caaaaatttt ataggaggtg
    19681 catcatgagc acatacgcaa tcatcaaaac tggtggaaaa caagttaaag ttgaagtagg
    19741 tcaagcaatc tacgttgaga aaattgacgc tgaagctggt gcagaagtca cttttaacga
    19801 agttgttctt gtaggtggtg acaaaactgt agttggtact ccagttgttg aaggagctac
    19861 tgtcgttgga actgttgaaa aacaaggaaa acaaaagaaa gttgtaacat tcaaatacaa
    19921 acctaaaaaa ggtagccacc gtaaacaagg tcatcgtcaa ccttacacta aagttgtcat
    19981 caacgcaatc aacgcttaat ttactagctt atgattaaag caatttttac tcgccaaaaa
    20041 aatggtcaac tgagcagtgt tacactgaca ggtcatgctg gtagtggtaa acatggcttt
    20101 gatattgttt gtgcctctgt tagtactcta gccattaact ttgttaattc tcttgaggtg
    20161 ttagcagatt gccaagcatt agtagatctt aatgatgttg aaggtgggta tatggctatt
    20221 acaataccac cacatgacaa caaggaggaa gttcaattat tatttgaatc ttttcttcta
    20281 ggaatgacta gtttggcgaa ggactcttcg aaatttgtca acactcaggt catctaaatt
    20341 taatttaaga gaggaaacaa cattatgtta aaaatgaatc ttgctaactt gcaacttttc
    20401 gcccacaaaa aaggtggagg ttctacatca aacggacgtg actcacaagc taaacgcctt
    20461 ggtgctaaag ctgctgacgg tcaaactgtt tcaggtggat caatccttta ccgtcaacgt
    20521 ggaactcata tctacccagg tgtaaacgta ggccgtggtg gagatgacac actttttgct
    20581 aaagttgaag gtgttgtacg tttcgaacgt aaaggacgcg ataaaaaaca agtttctgtt
    20641 tacccagtag ctaaataatt gtttaacatc gcattatata aggctttcca ggtgtctgga
    20701 aagccgattt tttttatttt gctacccata ttctaaaagc cgatgtagga agcgagcttg
    20761 tcagcagttt tatcttttga ggatttagta acatgagcgt agatattcat ggtagtttgg
    20821 atagtttcac gaccaagtgt attggatttt cttctatcct actaaagatt gtagttgctt
    20881 atttagagca atagttctaa ttgtaaaaag tcagcataat aaaacaatgt cataagatgt
    20941 tgttataacg ggctttatgg tataattaag gatactcatt ttaggaagga aagcaatgaa
    21001 tattcaacaa ttacgctatg tggtagccat cgctaataat ggaacttttc gagaagctgc
    21061 ctctaaattg tttgtcagtc agcctagctt atcagtttct atcaaagatt tagaggcgga
    21121 attagggttt caaattttta atcggactac ttcaggaaca gtcttgacaa gtcaaggact
    21181 agttttttat gagaaagctt tagaagtagt caagtctttt gattcttttg aaaaaacctt
    21241 ttctcaagct gatctggatc aaaatgaatt ttctattgct agccaacatt atgacttttt
    21301 gccacctctt attacagctt tttcgcaaca atacgatggt catcgtgtct ttcgtatctt
    21361 tgaatcaaca actattcaaa ttttagatga agttgctcaa ggaaacagtg aaattggtat
    21421 tatttacttg aatgtagaca atcaaaaagg tctctttcag cggatggata agctgggctt
    21481 agaatatgtt tctctaattc cttttactac tcatatttat ctttcaaaaa cgcatccatt
    21541 ggctaatcgc gaagcgcttt atttgaacga tattcaagga ttacctgcgg taaggtttac
    21601 ccaagaaagg gacgagtatt tgtattattc tgaaaatttt gtggatacta gtgaatgccc
    21661 tcgtatttat aatgtgtcag atagggcaac cttgaacggt attttagaga gaaccaatgc
    21721 ctttgcgaca ggatcaggtt ttctcgatca tcggagtgtt aatgggatta aagtgatacc
    21781 tctagctgat catattgaca atcaaatgat ttatgtcaaa cgaaaagata aaaacctttc
    21841 tgttgctggg gccacttttg tgactatttt aaaagactat tttgataaaa gaaggaaggc
    21901 cttaacatga aaaaacgatt gtttgtgctt agcttgatcc tccttgtagc tttggatcaa
    21961 cttagtaaat tttggattgt ttctcatata gcgcttggag aagtgaaacc ctttatccca
    22021 ggtatcgtca gcttgactta cttgcaaaac aatggggctg ccttttccat attgcaggac
    22081 cagcaatggt tctttgttgt cataacggtt ttagttatcg gttatgctat ttattacctt
    22141 gctactcatc cccatttaaa tatctggaaa caattagctc tcttgcttat tatttctggt
    22201 ggaatcggga attttattga tcgtttgcgt ttagcttacg tgattgatat ggttcattta
    22261 gactttgtgg attttgccat ttttaatgtg gcagattcat accttaccgt tggtgtcata
    22321 ttattagtga tatgtttatg gaaagaagag gattatggaa attaatgtga taacatcggg
    22381 gcaacgcttg gataaggcac tagctgattt aagtcccctg tcacgtggtc aagccaatga
    22441 ccaaattaag caaggccttg ttttagttaa tggtcagcaa aaaaaggcta aatatacggt
    22501 tcaagcagga gatgtgattt gttttgaact ccctaaagaa gaagtcttag agtaccaagc
    22561 tcagaatatt cccttggaca ttatctatga agatgatgct ctcgccatta ttaacaagcc
    22621 acagggaatg gtagttcacc cttcggcggg acacccttca ggaacaatgg ttaatgcctt
    22681 gatgtatcat atcaaggatt tgtcctcaat caatggtgtg gttcgtccag gaattgttca
    22741 tcggattgat aaggacacct caggtctctt aatggtagct aaaacagatg cagctcatca
    22801 agccttggca gaagaattaa aggctaaaaa atctctcaga aaatacctcg ccattgtcca
    22861 tggaaaccta ccgaatgatc gcgggatgat tgaagctcct ataggtcgta gcgaaaagga
    22921 ccgtaaaaaa caggctgtta cagcaaaagg caaagaagca gtgacacgtt ttacagtgct
    22981 agaacgtttt ggcgattaca gcctagtgga attacaactg gaaactggtc gaacgcacca
    23041 aattcgtgtt catatggcct atattggtca tcctgttgct ggggaccctt tatatggacc
    23101 acgtaagaca ctatcaggtc atggccaatt tcttcatgca aaaacattgg gattaacgca
    23161 tcctatgaca ggaaaagaaa tgatatttac tgttgaagct cccgaaattt ttcaaaaggt
    23221 gttaaagctg ctaagaaaaa aataaacagc gaggagtagc cattattttt agtcttatat
    23281 ctttgtgtaa agtttttaac attataaaaa atactaaaaa gcatttacga taagccagga
    23341 aatatgagaa gtcttttatg ttattgggat atgcaacata tctgttagag atctttattt
    23401 aaactcctta aagaaaagag atattccaaa tagatgctag gtattatcac gccaaacgca
    23461 tgaagaaact tttgttttca gaaaactaga ttcataatga caaaatcaat caaagtagta
    23521 cactatagat gaggtgacta cgatgattga ttttattatt tctattgatg attgcgcagt
    23581 tgaattggat agtcgtcaat cttggaaaat tcgctacccc ttatcaacca ttctatttct
    23641 tgtcttcgtt tgtcagttag ctggcattga aacctggaag gagatggaag attttattga
    23701 aatgaatgaa ccattgtttg cgacctacgt tgatttgagt gaaggttgtc cgtctcatga
    23761 taccttagag cgtgtgatta gtcttgttaa ttcagaccgt ttaaaagagc ttaaagttca
    23821 atttgagcaa tcattgacaa gcttagatgc cgttcatcaa ctgatttcag tggacggtaa
    23881 aacgattcga ggcaatcgag gtaaaaatca gaagcctgtt catattgtaa cggcttatga
    23941 tgggggtcat catcttagtt tgggacaggt agcggttgag gagaaaagta atgaaattgt
    24001 tgccattcct cagctattgc ggacaattga tatccgtaaa agcattgtaa cgatagacgc
    24061 aatgggcacg cagacggcta tcgttgatac gattataaaa ggtaaagcag actattgctt
    24121 agccgtcaaa ggaaatcaag aaacacttta tgatgatatt gctctttatt ttagtgatgt
    24181 caacttattg gaagaactcc aagaaaatgc gcagtattat cagactgttg aaaaatctag
    24241 gggacagatt gaagttagag aatgctgggt gtcttccgat atcaaatggt tgtgtcaaaa
    24301 ccatcccaaa tggaataagt tacgtggtat tgggatgact cgtaacacga ttgataagga
    24361 tggtcagctg agtcaagaga atcgttattt tatctttagc tttaagccgg atgtcctcac
    24421 atttgccaat tgtgtacgag gtcattggca gatagagagt atgcactggt tattggacgt
    24481 tgtttatcat gaagatcatc atcagacatt ggataaaaga gccgcattta acctaaatct
    24541 tatccgaaaa atgtgcttat attttctcaa agtgatggta tttcctaaaa aagacctcag
    24601 ttatcgtcgc aaacaacggt atatttctgt ccatttggaa gattatttag tccaattatt
    24661 tggagaaaga ggctaagcag atgattgatt taaaaaggaa tcttttcaaa attgatgtcc
    24721 gggcacaaaa ggatgaagag aaagttttca tgcgtacggc gtgggtattg tcttttttac
    24781 ttgtttttct tttctttttt tgctatactg attgaaataa aatattcctt taaaacagtc
    24841 ctgtgaggct gtcaaggaga cggattaaaa acatgcacca tgatacttaa ttgtgctata
    24901 ttttgctgaa tctccttgtt tccaaggaga tctttttatt tgaattttta gaggaggttt
    24961 caacatgaaa actaaggaaa ttgttgatga cgtgaccatg aaacgcgcca ttacccgtat
    25021 tacttatgaa attatcgaac gcaacaaaca attagacaat gtggttttgg caggaatcaa
    25081 aacgcgaggt gtttttttag cccgtcgtat tcaagaaaga ctgcatcaat tagaagggtt
    25141 ggatttacca attggtgagt tagacatcaa gccttttaga gatgacatga gagttgagga
    25201 agacacaact ctcatgtcag tagatattac aggcaaggat gtgattttga ttgatgatgt
    25261 gctttatact ggtcgtacca tccgcgcagc catcgataac ttagtgagtt taggtcgacc
    25321 agcccgtgtt agtctagctg ttttggtgga tcgtggccat cgggaattac cgattcgcgc
    25381 ggattacgtt gggaaaaata ttccaacaag cagtgtagaa gaaattgttg ttgaggttgt
    25441 cgaagtcgat ggccgtgatc gtgttagcat tattgaccca acataagaaa gaggttttac
    25501 tgtgaaagat gtcatttatg atgtggaaga agtgccaaag gcaggtatgt tagttggttt
    25561 gtcctttcag cacttatttg ctatgtttgg tgcgactgtt ctggttccca ttctagttgg
    25621 aattgaccca tcagttgctt tgttatctag tggtttagga acccttgccc acttatcagt
    25681 gaccaaattt aaaattccag cctacatggg ctcaagtttt gcttatatag cagctatgca
    25741 gttactgatg aagacaaatg gtattggtgc tgtagctcaa ggggctatga caggaggtct
    25801 cgtttacctg attgtagctt tgattgttaa agctattggc aatgattgga ttgataacat
    25861 cttaccaccg attgtggttg gtccgattgt tatggtcatt ggtctaagcc tagcttctac
    25921 agctgttaat gatgtcatgc taaaaaatgg gaactataat ctgacttatc ttgttattgg
    25981 gttagtcacc ttattatcag ttattttttt caatatttat ggtaaaggaa ttgttgctat
    26041 tgtaccaatt ttattggggc tattagttgg ttatgttgta gcccttttag tgggtgtttt
    26101 caccggtcaa gaaattgttg attttaccaa tgtggctcag gccaaatggt ttagtatccc
    26161 atcagtggaa attcctttct taacctacgg ggttaaattc tacccaagtg ccattttaac
    26221 tatggcaccc attgcctttg ttacaatgac agaacatttt ggacacatta tggtcttaaa
    26281 tagtttgaca aaaagagatt atttcaagga tccaggactt gaaaagactt taactggtga
    26341 tggttttgcg caaatcattg ccggcttctt aggggcacct ccggtcactt cttatggtga
    26401 aaacatcggt gtaatggctt tgaataaaat attctcggtc tatgttattg caggtgccgc
    26461 agtgattgcc gctctcctca gttttatcgg taaggtatca gccttaattc aatctattcc
    26521 aacaccagtt attggaggta tatcagttgc cttgtttggt gtgatagctt ctagcggttt
    26581 gaaaatcttg attgaatcca aagttgatat ggataataag aaaaacttat tgattgccag
    26641 tgttattttg gtctctggga ttggaggatt gatgcttcaa gtaaatggtc ttcaaatttc
    26701 aggtgtcgct ttctcaacac ttcttggcat catcttatat caggtacttt ctgaaaaata
    26761 ggaagaattg ttgttagacc atttacatag tcatcagtcg ttagtgataa aggggataat
    26821 catgtcagtt gtaaataatc gcgttgcact tactaattta gtttcaatgg aagcattaac
    26881 caccgaagaa gttttaggtc ttatcaaccg tggttcagaa tacaaggctg gtaaggttgt
    26941 tatttcggat catcaaaagg atcttgttgc caatttattc tttgaaaact ccacccgaac
    27001 ccataagtct tttgaagtgg ctgagaagaa actcggcttg acagttcttg atttcaatgc
    27061 tgatgcaagt gcggttaaca agggagaaag tttgtatgat actgtgttaa ccatgagtgc
    27121 acttggaaca gacatctgtg tgattcgtca cccagaagat gattattaca aggaattagt
    27181 agaaagtcca actattacag cttccattgt caatggagga gatggttctg gacaacaccc
    27241 gagtcaatgt ttacttgact tattaaccat ctatgaagaa tttggacgct ttgaaggctt
    27301 aaagattgcg atcgctggtg acttaactca ctctagggtg gcaaagtcca acatgcaaat
    27361 cctcaaaaga ttaggagcag agctttattt ctatggacct gaagaatggt attcagaagc
    27421 ctttaatgct tacggcactt atattgctat tgaccagatt attaaggaat tggatgttct
    27481 tatgttgctg cgtgtacagc acgaacgtca tgacggccat cagagttttt caaaagaagg
    27541 ttatcatcaa gcgtttggat tgacacagga acgttaccaa caattaaaag attctgctat
    27601 tattatgcat ccagctccag ttaatcggga tgtggaaatt gcagatagtt tggtggaagc
    27661 tcctaaagcg agaattgtat ctcagatggc taatggtgtc tttgttcgca tggctattat
    27721 tgaagccatt ttgaatggta gaaataaaaa ctcatgatga aagattaaag catgtttaga
    27781 aggtaggaaa aggtaggaaa atgacaaaac gattacttat tttagaagac ggcactattt
    27841 ttgaaggaga accctttggt gctgatattg atgtgactgg tgaaattgtc tttaatacag
    27901 gaatgacagg ctaccaagaa tccatcactg accaatccta caatgggcaa attttaacct
    27961 ttacctatcc tttgattgga aattatggga ttaatcgaga tgactatgag tccatttcac
    28021 ccacctgtaa aggggttgtt gtgtctgaag tcagtcggtt ggcaagtaat tggcgcaagc
    28081 aaatgacgct agatgcgttc ttgaaaataa aagggattcc agggatttcg ggaattgata
    28141 cgagagcttt gaccaaaatt attcggcaac acggtaccat gaaagctacg atggcagatg
    28201 atggagatag tatccagcat ttaaaagatc aactgcgtgc aacagtctta ccgactaaca
    28261 ccattgaaca agtgtcaact aaaacagctt atcctgcacc aggaatcggg aaaaatattg
    28321 tattggttga ttttggttta aaacattcta ttttaagaga attttctaaa agacaatgta
    28381 atatcaccgt tgtccctttc aacatcactg cagaagaagt gctccaacta aatccggatg
    28441 gcttgatgct atctaatggc ccaggaaacc cagaagattt gccagaggct ttagacatga
    28501 ttcgtggggt acaaggtaag attcctattt ttggtatttg tatgggacat caactcttta
    28561 gtctagcaaa tggtgccaag acttgtaaaa tgacctttgg tcatcgtggc tttaaccatg
    28621 ccgttagaga aattgcaacg ggaagaattg attttaccag tcaaaaccat ggttatgccg
    28681 ttgaacgtag tagtctacct gatactttaa tggttacgca tgaagacatt aacgataaga
    28741 cggtcgaagg agtgaaacat agagattttc cagctttttc agtccaattt caccctgatg
    28801 cggctccagg acctcatgat gccagctact tatttgacga atttttggaa atgattgatt
    28861 cttggagatg tacgagtaaa tagtaaatca gttgcaattt cacgactata tcacctcttg
    28921 ttactctatt tattaacatt tacagttgat ttagtaccct atcaaaaata ttatttaatg
    28981 ttgctctgtg aggcaacaaa tagagaaagg aaggcaagga gaacacaagt aaataattta
    29041 gtaaaaagtt aggttttcaa agagataaag ctcttattga gaagtgctga ctttaccgct
    29101 tcttgtggta ttcttggtat cattaattat gccaaaacga aaagatattc aaaaaatcat
    29161 ggttatcggg tctggcccga ttattattgg acaagctgct gaatttgatt atgcagggac
    29221 tcaggcctgt ttggctctaa aagaagaagg ctataaggtc atacttgtta attcaaatcc
    29281 tgcaacgatt atgacagata aagaaatcgc tgataaggta tatattgagc ctttgactct
    29341 tgaatttgtt aatcgtatca ttcgaaaaga aaggccagat gccatactgc caaccttagg
    29401 tggtcaaacg ggcctcaata tggcaatggc attatctaaa gctggtattc ttgatgattt
    29461 agagattgaa ttgttaggta ctaagttatc tgcgattgat caggcagaag acagagacct
    29521 tttcaaacaa ttaatgcaag aactagacca acccattcca gaatctacaa ttgttaaaac
    29581 agttgatgaa gctgttacat ttgctagaga tatcggttat ccagtcattg tgcgcccagc
    29641 ttttactctt ggtggaactg gtggaggaat atgtagtagt gaagaagaac tttgtgaaat
    29701 tactgaaaac ggcttaaagt tatcaccggt cacacagtgt ttgattgaac gctcaattgc
    29761 tggcttcaaa gaaattgaat acgaagtaat gcgagatagt gctgataacg cgctggttgt
    29821 ttgtaatatg gaaaactttg atcccgtagg gattcacaca ggagattcta ttgtatttgc
    29881 accaacacag accctttctg atattgaaaa tcaaatgtta cgtgatgcta gtttaaaaat
    29941 aattcgagct ctgaaaattg aaggtggctg taacgtccag ttagcactag atccttatag
    30001 tttcaaatat tatgttattg aagtaaatcc tagagtgtct cgttcctctg cccttgcttc
    30061 aaaagcaaca ggttatccca ttgccaaatt ggctgcaaag attgctgttg gcctaacact
    30121 tgatgaaatg attaacccta tcacaggcac tacttacgct atgtttgaac ctgcccttga
    30181 ttacgttgtt gctaaaattc cgcgttttcc gtttgataaa tttgaacatg gtgaacgcca
    30241 actgggaact caaatgaaag cgacaggtga agtcatggct attggccgta atttggaaga
    30301 gtccttacta aaagcctgtc gttctttaga aattggtatt tgccataatg agatgacaag
    30361 tttaagtaac attagcgatg aagagttagt gactaaagtg attaaagctc aagatgatcg
    30421 acttttttac ttgtcagaag caatacgacg aggttatagt atcgaagaac ttgagagctt
    30481 gaccaagatt gatttatttt tcttggataa attacttcat attgttgaaa tagagcaaga
    30541 attacaaatg catgttgacc atttggaaag cctcaaaaaa gcaaagcgtt atggattttc
    30601 agatcaaaaa attgcagaaa tttggcaaaa ggatgaaagt gatatcagag cgatgagaca
    30661 ttctcatagc ctgtatcctg tctataaaat ggtagatact tgtgcagctg aatttgatgc
    30721 taaaacccct tatttttatt caacatatga gttggaaaat gaatctgttc agtcgaataa
    30781 agaatcaatt ttagttttag gttcaggccc tattcgtatt ggtcaagggg ttgaatttga
    30841 ctacgcaacg gttcattctg ttaaagccat ccaaaaagct ggctatgaag ccattatcat
    30901 gaattcaaat ccggagactg tatctacaga tttttcggta tcagataaat tatattttga
    30961 accgttaacc tttgaagacg tcatgaatgt gatagattta gagcagccta agggagtaat
    31021 agttcagttt ggaggacaaa ctgctattaa cttagcacaa gcactttctg aggcgggtgt
    31081 tacaatatta ggaacacaag tagaggattt ggatagggct gaagacagag atttatttga
    31141 aaaggcgttg aaagagcttg gaatcccaca accacaaggt caaacggcaa ctaatgaaga
    31201 agaagcttta gaggcagcta aaaaaattgg ttttccagtc ttagttagac cttcttacgt
    31261 acttggtggc cgggctatgg aaattgttga aaacaaagaa gatcttagag aatatataag
    31321 aacagcggtt aaagcaagtc ctgaacatcc tatcttagtg gactcttata ttttcggtaa
    31381 ggagtgtgaa gtggatgcca tttcagatgg aaaatcagtc ttaattcctg gtattatgga
    31441 gcacatcgaa agagcaggtg ttcattcagg agattcaatg gcagtttatc cgccacagca
    31501 attatctaag caaattcaag aaacaatagc tgagtatact aaacgtttag ccattgggtt
    31561 aaattgtatt ggtatgatga atgttcaatt tgttattaaa aatgaacaag tctatgttat
    31621 tgaagtgaat ccacgcgcta gtcgtaccgt gcctttctta tcaaaagtaa caggtattcc
    31681 gatggctcag attgctacta agttgatttt aggtcaaaca ttaaaggatc taggatatga
    31741 agatggtctt tatccccaaa gtcaactggt gcatatcaaa gcgcctgtgt tttcatttac
    31801 aaagttggca caggttgata gtcttttagg tcctgaaatg aaatcaactg gagaagtaat
    31861 ggggtcggat actagtcttg aaaaagcact ttataaagcg tttgaagcca ataattctca
    31921 tttatcagaa tttggtcaaa ttgtctttac tatagcagat gatagtaagg cagaagctct
    31981 aagtctagca agacgattta aggcgattgg ctatcaaatt atggctactc aaggtacagc
    32041 agcttacttt gctgagcaag gcttaagcgc gtgtttagtt ggaaaaattg gtgatgctgc
    32101 caatgacatc ccgacactcg tgcgacatgg tcacgttcag gcaattgtta atacagttgg
    32161 aattaaacgc acagctgata aagacggaca gatgattaga agttcagcta ttgaacaagg
    32221 agttccttta tttacagctt tagatactgc aaaagctatg ttaacggttt tagaaagcag
    32281 atgctttaac atcgaagcga tataaaaatt aaaaaatcat ttttaagaaa acttaaaaat
    32341 gattttttta gattataatg acaaaagttt cagtaagcta ttaatttgtc atagcatata
    32401 agtcattatc ttgtggcttg ttttcgacta agggctaaga atttcttgac aacaatataa
    32461 aaaggtcata tacttgtctt atacaaatag tacaaaaagg ggaggataga aatgtctaaa
    32521 agaggaaaaa ttaaaataac aacgaaaaca aagcttatta cagctagtgt tataacgcta
    32581 gtattaatta taactggagt agtcttgtgg aaacaacaac aaaatacgct aacaactgat
    32641 atcgctaaag aaccttactc tactgttagt gtaactgaag ggagtattgc ttcttcgact
    32701 ttactatcag gtactgtaaa ggctttatca gaggaatata tttattttga tgctaataaa
    32761 ggaaatgatg caactgttac agttaaagta ggtgatcagg taacgcaggg ccagcaatta
    32821 gttcaatata atacaacaac agctcagtca gcttatgata ctgctgttag gagtcttaac
    32881 aagattggcc gacaaattaa tcatcttaaa acatacggag ttcctgctgt tagtacagaa
    32941 actaataaag atgaagctac cggtgaagag acgacaacaa cagttcaacc atcagctcag
    33001 caaaatgcta attataaaca gcagctgcaa gatttaaatg atgcttatgc agatgcacaa
    33061 gcagaagtaa ataaagcgca gatagcgtta aatgatacag tagttatcag tagtgtctct
    33121 ggaactgttg tggaagtaaa taatgatatt gatccttctt caaagaacag tcaaacactt
    33181 gttcacgtag caaccgaagg acagcttcag gtgaaaggaa cattgacaga gtatgattta
    33241 gcaaacgtta aggttggtca atctgtaaaa attaagtcta aagtttattc taatcaagaa
    33301 tggactggaa aaatatcata tgtttcaaac tatccaactg agtctaatgc aggttcaaca
    33361 acgccagcag gtagcactgg agcgggaagt tctacaggag ttgcctatga ttacaagatt
    33421 gatattataa gtcctctcaa ccagcttaaa caaggcttca ctgtttctgt tgaggttgtt
    33481 aatgaagcaa aacaggcctt agttccttta acggctgtta ttaagaaaga taaaaaacac
    33541 tatgtttgga cttatgatga tgctactggc aaagccaaaa aagtagaggt gacactggga
    33601 aatgcagatg cacaacaaca agaaattcat aaaggagtag ctgttggtga cattgttatt
    33661 gccaatccag ataaaaatat caaaccggat aaaaaactag aaggggttat ttcaataggt
    33721 accaacacaa aaccggaaaa agattctcaa tcaaagaata aaaaatcagg ggtggataaa
    33781 tagtgtcgca tgaaaaaaaa caattaatgc aattatcaaa tattgtgaag agctatcaaa
    33841 atggggatca agttcttaaa gttttgaaag gtattaattt aacagtatat gagggtgaat
    33901 ttttagctat tatgggtccg tctggctcgg gaaaatcaac actaatgaat attattggtt
    33961 tattagatcg gccaacatcc ggagattaca cattacataa tactaaaata gaaatcctta
    34021 atgatcgtga gttagcaaaa gtacgaaatg atgaaatcgg ctttgtcttt caacaattct
    34081 ttctgttagc taaattaact gcattacaaa atgttgagtt gcctcttatt tatgctggtg
    34141 taaacgtctc aaaaagacgt gaacaggcta agcaatttct tgaaaaagta ggacttggac
    34201 gacgtatcaa acatctaccg tcagaactgt caggaggtca aaagcaaagg gtggctatcg
    34261 cacgagcttt agtaaatgac ccatctatta ttttagcgga tgaaccaaca ggtgcactag
    34321 atactaaaac aggtcagcaa attatggaac tcttgacaga gttaaacaaa gaaggtaaaa
    34381 caattattat ggttactcat gaaccagaaa ttgctgattt tgcaactcgg aaaattatta
    34441 ttcgtgatgg tgatatcaca acggatacta cagctagtgt tgttattgac taggaggaaa
    34501 aataatggaa aattggaaat tcgctcttag ctcaatttgg gggcataaga tgcgctcaat
    34561 cctgacaatg ttgggaatta tcatcggtgt agcagcagtt gtgattatta tggggttggg
    34621 aaatgctatg aaaaatagtg taacaagcac attttctagc aagcaaaaag atattcaact
    34681 ctattttcaa gaaaaaggag aagaagaaga cctgtatgcc ggattgcaca cgcatgaaaa
    34741 taatcacgaa gtgaagccag agtggttaga acaaattgtt aaagatatcg atggtattga
    34801 ttcttattac tttaccaatt ctgctacttc tactatttcg tatgaaaaaa agaaagtaga
    34861 caatgcttcg atcatagggg taagtaaaga ttattttaat ataaaaaact atgatatcgt
    34921 agctggtcgt acactaacag ataatgatta ttctaatttt tcgcgtatca ttcttttaga
    34981 tacagtatta gccgatgacc tatttggcga aggtaattat aagtcagctt taaataaagt
    35041 ggtaagttta tctgataaag attatttagt tattggtgtt tataaaactg atcagacgcc
    35101 agtttctttt gatggattat caggcggcgc tgtcatggca aatactcagg tagcttcaga
    35161 gtttggcacc aaagaaatag gatctatcta cattcatgtg aacgatattc aaaacagtat
    35221 gaacttagga aatcaagcag ctgatatgct aaccaacata tcgcacatta aagatggaca
    35281 gtacgctgtt cctgataata gcaaaatcgt tgaagaaatc aatagtcagt tcagtatcat
    35341 gacaacagtc ataggttcaa ttgcagcgat ctctctttta gtgggaggaa ttggtgttat
    35401 gaatattatg ttggtatctg tcacagagcg aactagagaa attggtttac gtaaagcact
    35461 tggtgcaaca cgcctgaaaa ttttatcaca atttttgatt gaatccgttg ttctaacagt
    35521 tcttggaggc ttgataggat tattattagc tcaattaagt gtaggggctt taggaaatgc
    35581 gatgacatta aaaggagctt gtatttctct tgatgtggcc ttaatagcag ttttattttc
    35641 tgcctcaata ggtgtctttt ttggaatgtt gccagctaat aaagctagta agttagatcc
    35701 aattgaggca ttacgttatg aatagaatag ttcgtatcaa tcaatctata gacgctgact
    35761 agtttaacgt ctgattatat ctattttttg tattagcaca gtagttatat cattgaagtg
    35821 ttagtgcatt ttttgaggtg ataatatcta gcaaagctat cattggtatg atgatgtgga
    35881 tagcgtataa gtgatacatc tcttatttct agctgaactt cggttcggct aggaagttgt
    35941 caggcaatga gttgtttaaa ataaaggaga ttagttcaat gacattttta tctgatttga
    36001 tatcattaat gacaaaaatc agattatctt gggtaataaa ggcgggtatt tttcaattat
    36061 tatttgtaac gattgctaat attgtcttat cagaattttt ctattttata ttagacgtta
    36121 ctggtcaata tcatttagat aaagacaatg ttgtgacttt tttaaaaaat cctatagcac
    36181 ttgctttatt aggtgcctat ttatttttat tagctgcttt tattcacctt gagttttttg
    36241 ctctatatcg aattattgcg gatcaagaaa ttagtttcta tctttttaga aaacagtttt
    36301 cttattacct aagggggctt tggaaaacat tttctggtta ccaattatta ctttttttgc
    36361 tttatatcct attgactatt ccagtcttac atattggttt atcttctgtg attactcaaa
    36421 agctttatct tccagaattt attgttgggg aattatcaaa gataactagc acaaagtact
    36481 tgctttatgg cagtcttatt cttgtatttt accttaacct aagattagta tattttttac
    36541 cattgatagc aatcaaccat cgtacggttg ctcaagcatg gagagagagt tggcaaaaga
    36601 ctaaaaagaa acatgtattg ttatggatga aactttttgc aatcaatggt cttacgcttg
    36661 tagtcgtatc gctagctatt tccatgattc ttatttttgt tgatatgttt aatcctaagg
    36721 ggaataatat tattgttcag ctgggagctt tgacctttac atgggaactc atttttttta
    36781 ctactatttt ttttaaactc tgttcagcaa tgattttaaa agaggcaatt gaaccacaaa
    36841 agcaatatga tgagccaaga agaagtaata aggcatatgt tgtaatcttt atcgtggtga
    36901 cagtaggttt tgcttatcaa tctcttgaac gtttaacttt ttttgacaca tctcactcta
    36961 agacagttat cgcgcataga ggacttgtat cagcaggtgt agaaaattct ctggaagccc
    37021 ttgaaggtgc taagaaagca ggaagtgatt atgtagaact ggatctaatc ttgactaagg
    37081 ataatcactt tgtggtgtct catgataatc gattgaagcg tttagctgga gtaaataaga
    37141 cgattcgcaa cttaacctta aaagaagttg aacatctaac gagtcatcaa ggacattttt
    37201 cagggcgttt tgtttctttt gacacttttt atcaaaaggc taagaagttg aatatgccat
    37261 tacttattga actcaagcca attggtacag aacctggaaa ttatgtcgat ttgtttttag
    37321 aaacttatca tcgacttggt ataagcaaag ataataaagt catgtcttta gatttagaag
    37381 taatagaagc tatcaagaaa aaaaatccat caattacgac tggttatatc ataccaattc
    37441 aatttggatt ttttggagat gaatttgttg atttctatgt cattgaagac ttttcttatc
    37501 ggtcttattt gtcgtcccaa gctttttgga ataataaaga aatttacgtt tggactatta
    37561 atgatcccaa gcgcatagag cattatctcc taaagcctat tcagggaatt attacagatc
    37621 aaccagcttt aactaatcaa ttgattaaag acttaaaaca agataattct tattttagtc
    37681 gattagtcag aattattagt agtctttatt aaaggtttaa agaaagtgtc aagaaaaaaa
    37741 cttgacactt tctttaaact gagttatact gtttaacata ggaatttagc gtagctgtat
    37801 ttcttataca ttactaaaag aaaagagact atttaaaaat ggcagtaaaa atccgtttaa
    37861 ctcgtatggg ttctaagaaa aaacctttct accgtattaa tgttgcagat tcacgtgcac
    37921 cacgtgatgg tcgttttatc gaaacagttg gaacatacaa cccattagtg gctgaaaatc
    37981 aaattactat taaagaggat cgtgttcttg agtggttatc taaaggagcg cagccttctg
    38041 ataccgttcg taacatcttg tctaaagctg gtgttatggc taagttccac gaccaaaaat
    38101 tctctaaata ataacagcct atggatacca ttgaaaatct tattatcgct attgtgaaac
    38161 ctttgatttc acaaccagat aatcttacca ttaaaattga agatactcct gactttttag
    38221 agtatcatct tgacttggat gctcaagaca tcggtcgtgt tatcggcaaa aaaggtcgaa
    38281 ctattactgc gataagatcg attgtctact cggttccaac actaggaaaa aaagttcgct
    38341 tagttattga tgagaaataa tcactaactt gagatggatt gaaaagcttg ttgactttaa
    38401 gtcaacaagc tttttgaata gcaaaaatct taatatttct gaaatgaaaa gattagattt
    38461 ttctgtcttt agctaaaaag aagttaaaga atggcttagc tgattgcctt tataagagat
    38521 tatactggtt tttgatagct gctgtcatgt aaaatagcta caattcatct tacgagatag
    38581 tctttatttt ccaacctgct gtttgttgta tgtttatagt tccctaaaat taagtatact
    38641 taattttagg aatgtttata ttctttacat tctgatgaaa atacaaatta tcctaacatg
    38701 atgtattgaa aggggaaata gtttatgtta gtatactgat taagtgaagc tgtaatgagg
    38761 cttatacgat caaaaaagtt agagtaactt tataaaacag tggtgttgaa gcaagtttag
    38821 cttcttctca gaaatagatt atctataaaa aatcccaaaa gtagtttgtt tccagttaat
    38881 gaacttcttt tgggaaggct tttttgctga tcgccacttc acttgtatat cgggaacatt
    38941 cacgctaaga tgtataagtt gaatcgtttg tctatggctt gatgaaaatt aatcaaaaga
    39001 taatgttcaa ctctataatt agtacaagca aaatgagata acttattcat tagtaagcat
    39061 aagatataac aag
//
LOCUS       DAUGSW010000014        36403 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUGSW010000014 DAUGSW010000000
VERSION     DAUGSW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36403
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.014"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            229..1464
                     /gene="arcA"
                     /locus_tag="VIB18_000845"
     CDS             229..1464
                     /gene="arcA"
                     /locus_tag="VIB18_000845"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEQ8765868.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAKLLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1564..1992
                     /locus_tag="VIB18_000846"
     CDS             1564..1992
                     /locus_tag="VIB18_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8765869.1"
                     /translation="MADEFDAHDEKGTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQAYGSKYLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            2032..3045
                     /gene="argF"
                     /locus_tag="VIB18_000847"
     CDS             2032..3045
                     /gene="argF"
                     /locus_tag="VIB18_000847"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEQ8765870.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3215..4708
                     /locus_tag="VIB18_000848"
     CDS             3215..4708
                     /locus_tag="VIB18_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEQ8765871.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGLFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4725..6056
                     /locus_tag="VIB18_000849"
     CDS             4725..6056
                     /locus_tag="VIB18_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEQ8765872.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFYTYIDPKGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTEPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEICLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAAQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            6076..7026
                     /gene="arcC"
                     /locus_tag="VIB18_000850"
     CDS             6076..7026
                     /gene="arcC"
                     /locus_tag="VIB18_000850"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEQ8765873.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7339..8331
                     /locus_tag="VIB18_000851"
     CDS             7339..8331
                     /locus_tag="VIB18_000851"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEQ8765874.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTIETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            8454..8993
                     /gene="rsmD"
                     /locus_tag="VIB18_000852"
     CDS             8454..8993
                     /gene="rsmD"
                     /locus_tag="VIB18_000852"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEQ8765875.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8983..9474
                     /gene="coaD"
                     /locus_tag="VIB18_000853"
     CDS             8983..9474
                     /gene="coaD"
                     /locus_tag="VIB18_000853"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEQ8765876.1"
                     /translation="MLTKVGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9461..10498
                     /locus_tag="VIB18_000854"
     CDS             9461..10498
                     /locus_tag="VIB18_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEQ8765877.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10912..11889
                     /locus_tag="VIB18_000855"
     CDS             10912..11889
                     /locus_tag="VIB18_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8765878.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFESIQ
                     LEASYNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            12313..12957
                     /locus_tag="VIB18_000856"
     CDS             12313..12957
                     /locus_tag="VIB18_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEQ8765879.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRISKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12961..14040
                     /gene="rlmN"
                     /locus_tag="VIB18_000857"
     CDS             12961..14040
                     /gene="rlmN"
                     /locus_tag="VIB18_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEQ8765880.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(14122..14748)
                     /locus_tag="VIB18_000858"
     CDS             complement(14122..14748)
                     /locus_tag="VIB18_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEQ8765881.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLMSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            14976..15503
                     /locus_tag="VIB18_000859"
     CDS             14976..15503
                     /locus_tag="VIB18_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEQ8765882.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            15645..15848
                     /locus_tag="VIB18_000860"
     CDS             15645..15848
                     /locus_tag="VIB18_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEQ8765883.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            15853..16824
                     /locus_tag="VIB18_000861"
     CDS             15853..16824
                     /locus_tag="VIB18_000861"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEQ8765884.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            16834..17223
                     /locus_tag="VIB18_000862"
     CDS             16834..17223
                     /locus_tag="VIB18_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEQ8765885.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRTKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            17406..19247
                     /gene="typA"
                     /locus_tag="VIB18_000863"
     CDS             17406..19247
                     /gene="typA"
                     /locus_tag="VIB18_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEQ8765886.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            19369..19620
                     /locus_tag="VIB18_000864"
     CDS             19369..19620
                     /locus_tag="VIB18_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEQ8765887.1"
                     /translation="MFYLIMAVSIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            19976..21334
                     /locus_tag="VIB18_000865"
     CDS             19976..21334
                     /locus_tag="VIB18_000865"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEQ8765888.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTQATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            21334..22416
                     /locus_tag="VIB18_000866"
     CDS             21334..22416
                     /locus_tag="VIB18_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEQ8765889.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            22417..23565
                     /locus_tag="VIB18_000867"
     CDS             22417..23565
                     /locus_tag="VIB18_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEQ8765890.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAFQK
                     SFPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMHDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQTPPSPETVLEQAHG"
     gene            23777..25141
                     /gene="ftsA"
                     /locus_tag="VIB18_000868"
     CDS             23777..25141
                     /gene="ftsA"
                     /locus_tag="VIB18_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEQ8765891.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            25165..26484
                     /gene="ftsZ"
                     /locus_tag="VIB18_000869"
     CDS             25165..26484
                     /gene="ftsZ"
                     /locus_tag="VIB18_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEQ8765892.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            26487..27158
                     /locus_tag="VIB18_000870"
     CDS             26487..27158
                     /locus_tag="VIB18_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEQ8765893.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIESGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            27170..27826
                     /locus_tag="VIB18_000871"
     CDS             27170..27826
                     /locus_tag="VIB18_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEQ8765894.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            27831..28085
                     /locus_tag="VIB18_000872"
     CDS             27831..28085
                     /locus_tag="VIB18_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEQ8765895.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            28085..28876
                     /locus_tag="VIB18_000873"
     CDS             28085..28876
                     /locus_tag="VIB18_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEQ8765896.1"
                     /translation="MISHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYLSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQPLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGQQKITLSKMIHK"
     gene            28886..29644
                     /locus_tag="VIB18_000874"
     CDS             28886..29644
                     /locus_tag="VIB18_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEQ8765897.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            29917..32718
                     /locus_tag="VIB18_000875"
     CDS             29917..32718
                     /locus_tag="VIB18_000875"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEQ8765898.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQQDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     DILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGVAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(32983..33285)
                     /locus_tag="VIB18_000876"
     CDS             complement(32983..33285)
                     /locus_tag="VIB18_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEQ8765899.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(33336..33791)
                     /locus_tag="VIB18_000877"
     CDS             complement(33336..33791)
                     /locus_tag="VIB18_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8765900.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLSWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(33919..36201)
                     /locus_tag="VIB18_000878"
     CDS             complement(33919..36201)
                     /locus_tag="VIB18_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8765901.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRIIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKHLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
BASE COUNT        11501 a         6408 c         7619 g        10875 t
ORIGIN      
        1 ttaatttata agtataaatt tttacactaa gatgtaaaaa acatacaagt aaacgaatac
       61 aaatctataa aaataaaaac aacgctcaaa aaatgtaagc gattactcaa aatagctgtg
      121 agaaataccc tatttttatc ttttttaagg agtacactag gaatataagc aagagttaag
      181 aatcttgacg gtgaattcac aaaaaccaat tagaaagagg taattcttat gactgctcaa
      241 acaccaattc atgtttattc tgaaattgga aaattaaaaa aagtgttgct ccacagaccc
      301 ggtaaagaaa ttgaaaatct tatgccagac tacttggaac gcttgttgtt tgatgacatt
      361 ccattcttag aggatgccca aaaagaacat gatgcttttg cccaagcttt acgtgacgaa
      421 ggtattgaag tcttgtacct tgagacctta gctgcagaat ctcttgtcac tccagaaatt
      481 cgcgaagctt tcattgatga atacctaagt gaagctaata tccgtggaag agctactaaa
      541 aaagccattc gtgagttgtt gatggctatc gaagacaatc aagaattgat tgaaaaaacc
      601 atggcagggg ttcaaaaatc tgaacttcca gagatcccag catctgaaaa aggcttgact
      661 gacttggttg aatccagtta cccatttgcg atcgacccaa tgccaaacct ttatttcaca
      721 cgggacccat tcgcaactat cggtacaggt gtttctctta accacatgtt ctcagaaaca
      781 cgtaaccgtg aaacccttta tggtaaatac attttcactc atcacccaat ttatgggggt
      841 ggcaaagtgc ctatggttta tgaccgtaat gaaactactc gcattgaagg tggggacgaa
      901 ctcgttcttt caaaagatgt gcttgcggtt ggtatttctc aacgtacaga tgctgcttct
      961 attgaaaaat tgttggttaa catctttaaa caaaaccttg gcttcaagaa agtattggcc
     1021 tttgaatttg caaataaccg taaattcatg cacttagaca ctgtctttac catggttgac
     1081 tatgacaaat tcaccattca cccagaaatt gaaggcgacc ttcgtgttta ctctgtcact
     1141 tacgacaatg aagaacttca tattgttgaa gaaaaaggtg atttagcaaa acttcttgct
     1201 gctaaccttg gtgttgaaaa agttgacctt atccgttgtg gtggtgacaa cttagtagca
     1261 gcaggtcgtg aacaatggaa cgatggttct aacaccctta ctatcgcacc aggtgtggtt
     1321 gtggtttata accgtaacac tattaccaat gccattcttg aatctaaagg cttgaagttg
     1381 atcaagattc acggaagtga attggttcgc ggtcgtggtg gacctcgttg tatgtcaatg
     1441 ccatttgaac gtgaagatat ttagtaagtt atggtaaagg tgattgtagg tcaggagcct
     1501 tttcaaaggg cagctagtct gtatcttcgc ttctgtgtct ttgtccttga acgaaacttt
     1561 gccatggcag atgaatttga tgcccatgat gaaaaaggga cggtttatgc agtcgtttac
     1621 gacaatgacc agcccgtttc aacaggacaa tttttagctg aaacgaaaat agaagcacga
     1681 ttgacacgca ttgtaacctt agcagattat tgtggttgcg gctatggtgc caaagtcact
     1741 gaagcgctag aaacttatac cagacgagaa ggcttttacc aactaaccat tcacagtgaa
     1801 ctgacagcac aaacctttta tgaaaaccta ggttatcagg cctatggttc caagtattta
     1861 gaagatggtg agtattgtca atcccttgca aaaaccattc ttaaatggga gaagaatatg
     1921 gacatagcaa tgctaattgc gattgttggt ggtctattag gctgctatct ctatctcaca
     1981 aaaaataatt aatcaaaaca gattacagtt aacactcgaa ggagacaata gatgacacaa
     2041 gtatttcaag gacgtagctt cctagcagaa aaagatttta cacgcgctga attagaatac
     2101 cttattgatt tttcagctca tttgaaagat ttgaaaaaac gtggtgtgcc tcatcactac
     2161 ttagaaggta aaaacattgc cctcttgttt gaaaaaacat caactcgtac gcgtgcagct
     2221 tttacaacag cagccattga cctaggtgct cacccagaat acctcggtgc caatgacatc
     2281 caacttggta aaaaagaatc aactgaagac actgccaaag tattgggtcg tatgtttgat
     2341 gggattgaat tccgtggctt tagccaacgc atggttgaag aattggcaga attctcaggt
     2401 gtgccagttt ggaatggttt gactgatgaa tggcacccaa cccaaatgct tgctgactat
     2461 ttaacagtga aagaaaactt tggcaaactt gaaggcctta cccttgttta ctgtggtgat
     2521 ggacgtaata acgttgccaa ttcccttctt gtgactggtg ctatccttgg tgttaatgtt
     2581 catatcttct caccaaaaga actcttccca gaagaagaga ttgtgacatt ggctgaaggc
     2641 tatgctaaag aaagtggcgc tcgtatcctt atcacagaag atgctgacga agctgttaaa
     2701 ggcgcagacg tgctttacac agatgtttgg gtatcaatgg gtgaagaaga caaattcaaa
     2761 gaacgtgttg aattgcttca accatatcaa gtcaacatgg accttgttca aaaagcagga
     2821 aatgacaagc ttatcttctt gcactgcttg ccagctttcc atgatacaaa taccgtttat
     2881 ggtaaagatg ttgctgaaaa attcggcgtg aaagaaatgg aagtcactga tgaagtcttc
     2941 cgcagcaaat acgctcgtca ttttgatcaa gctgaaaacc gtatgcacac tatcaaagcg
     3001 gttatggcag caacccttgg taacctcttt attccaaaag tgtaataagg actggtactc
     3061 cttaactcat ttcacatatc aatgtgaccc ctttaattta acaatttaac tacttaaaaa
     3121 cgtactttaa ctacatgaca agtcgttctg gttttcgcgt ccttgaccgg aactagaacg
     3181 gcttattttt atgaaaaggt aagaggtaat cattatgaca gaagaaaaaa aacggggttt
     3241 tagaattcct tcttcttaca ccgttctttt tatcattata gccatcatgg cagtgttaac
     3301 ttggtttatt ccagctggcg cctacgaaac cgctaagggc ggtggtgtta tttcaggaac
     3361 ctacaaaaca gtagcatcca atcctcaagg attgtttgac atcttgatgg ctcccgttcg
     3421 aggcatgtta ggtgttgaag gcactgatgg tgctattcaa gtgtctttct ttatcttaat
     3481 ggttgggggc tttttaggag ttgtcaacaa aacaggtgct cttgacacag gaattgcgtc
     3541 agtggttcgt aaaaacaaag gtagagaaaa aatgctgatt gctattttaa tccctttgtt
     3601 tgctctaggt ggaacgacct atggtatggg ggaagaaacc atggcctttt acccactttt
     3661 aattcctgtt atgattgcgg ttggttttga cagtattgtt gctgtagcca ttattttgat
     3721 tggttctcaa attgggtgtc tagcctccac tattaaccca tttgcaactg gtgtagcagc
     3781 tgatgctgct ggtgtcagca ttgcagatgg aatgatttgg cgtgttatcc aatgggttat
     3841 tcttgtcggc atgtctattt ggtttgttta caattacgct agtaagattg aagaagaccc
     3901 aagtaaatca ttggttgcag acaaggaaga agagcataag gaactcttcc agttgcaaaa
     3961 ttctggagaa gacttaaaca agcgccaacg aaacgttttg accattttta ctttgacctt
     4021 tgtcattatg attcttagtt tgattccgtg ggaagatttt ggcatcaaat tctttactaa
     4081 tatcaatact tggttaacca caatgcctat cttaggggga gttattggga aaaccatggg
     4141 agcatttggt acttggtatt tcccagaaat caccatgctc tttatcatga tgggtgtctt
     4201 agttgctatt gtttatcgta tgagtgaaga agactttttt agctcttttt tgactggtgc
     4261 aggtgaattt ttaggtgttg ccatgatctg tgctattgca cgcggtattc aagttatcat
     4321 gaatggtggt atgattacag ccactatctt acacttaggt gaaacaagtc tttctggttt
     4381 atcttctcaa gtttttgtga tattagctta tattttctac ctcccaatgt ccttcttgat
     4441 tccatcaaca tcaggacttg ctggggctac aatggggatt atggcaccgc ttggacaatt
     4501 ctcaaatgtc cctgctcacc ttgttattac agccttccag tcagcttctg gaatcttaaa
     4561 catgatttct ccaacttcag caatcgttat gggagcactt gcgcttggtc gcgttgacct
     4621 tggtacttgg tggaaattca ttggtaaatt tattgtaatg gtgatgcttg taagcgtgct
     4681 attacttgta gttgcaacat tcttttaaca gataggaggt tcctatggaa tcctatatca
     4741 cacctaaaca tcaagaggcc tgtgtagctg ccattaaaca gatcgtttct tacccttctg
     4801 tttgtcatga aggagaaaat ggcacacctt ttggacaggc cattcaagat gttctcgaag
     4861 caaccttaga cttatgtcaa ggtcttggct tctatactta tattgatcct aaaggttact
     4921 atggctatgc tgagttaggt gaccaaaaag aggtcttggc tattctgtgc catttggacg
     4981 ttgttccaga aggagatcgt cagttatgga agacagagcc ttttgactgt gttgaggcag
     5041 acggctgttt atttggtcga ggcactcaag acgataaagg gcctactatg atggcactat
     5101 ttgccaccaa agccttgata gatgcaggcg ttacctttaa taaacgcatt cgttttattt
     5161 tcggaacaga tgaagaaact ttgtggcggt gtatgaatcg ctacaatgat gtagaagaac
     5221 aggctacctt tgggtttgct cctgattcaa gtttcccttt aacctatgcc gaaaaaggcc
     5281 tacttcaggc aaaattagtg gggaaaggtt ctgataaact gtcacttgaa atcggacaag
     5341 cctacaatgt tgttcctgca agagcctctt atcaaggtga taagcttgag gctttacaaa
     5401 aagaactaga taagcttggc tttgagtacg tcgtcaaaga gggagaatta acggtttatg
     5461 gtctcgccca acatgctaaa gatgctcccg atggcatcaa cgctatgatt aggcttgcca
     5521 aagctttagt ggtccttgaa cctaacaaaa cccttgattt tcttgctaat gtcattgatg
     5581 aagatggcag agcacttaat atttttggca gaatcgaaga tgaaccttca ggcaaattaa
     5641 gctttaatgc cgcagggctt accttaacca aagacaaggc agaaatttgc ctagatattc
     5701 ggattccagt tttggcagat aaggaaaaat tagtccaaca attaagccaa aaagcacaag
     5761 aatacggcct aacctatgaa gaatttgatt atttggcccc attatatgtg ccattagaca
     5821 gtgaattggt aacaaccttg ttatctgtct atcggaaaaa aacaggtgat caaagccctg
     5881 cccaatcatc aggaggggca acctttgcta gaacaatgaa gaattgtgtt gcctttggtg
     5941 cccttttccc tgatgctgct caaacggaac accaagaaaa tgaacatatt gttttagcgg
     6001 atgcttaccg cgctatggat atttatgcgg aagctattta ccgactaacg cgataacaag
     6061 atatgaggag taattatgac gaaacaaaaa atcgtagtcg cacttggagg aaatgctatt
     6121 ctttcaacag atgcgtcagc aaaagcacaa caagaagcct tgatttccac atcaaaatca
     6181 ttggttaaat taattaaaga aggtcatgaa gtcatcgtga cccacggcaa tggcccacaa
     6241 gttggtaatc tcttattaca acaagcagcg gcagattctg aaaagaatcc ggctatgcct
     6301 ttggatactt gtgttgccat gacagaaggt agcatcggtt tttggttagt taatgccctt
     6361 gataatgaat tgcaagccca aggtattcaa aaagaagtgg cagctgttgt cactcaagtg
     6421 atcgtggatg ccaaagaccc agcttttgaa aacccaacaa aaccaattgg tccatttctt
     6481 accgaagaag atgccaaaaa acaaatggcg gagtctggtg caagtttcaa agaagatgca
     6541 ggtcgtggct ggcgtaaggt tgtgccatca ccaaaaccag ttggtattaa agaagccaat
     6601 gtcatcagaa gtctcgttga ttctggcgtt gttgtggtta gtgctggtgg tggtggtgtg
     6661 cctgttgtgg aagatgcaac tagcaagtcc ctgactggtg tggaagctgt tattgacaag
     6721 gactttgcta gccaaaccct ttcagaattg gtggatgcag acctctttat cgttttgaca
     6781 ggagttgaca atgtttacat caacttcaac aaacctgacc aagccaaatt ggaagaagtg
     6841 actgtctctc aaatgaaaga atacatcaca caagaccaat ttgcaccagg tagtatgtta
     6901 ccaaaagtgg aagctgccat tgcttttgtt gaaaacaaac caaatgctaa agccattatc
     6961 acatcgctcg aaaatattga caatgtacta tcagcaaacg ctggaacaca aattatcgca
     7021 gggtaatcaa gaggattttt agttctgttt aaaagactca tttaatggta ttttctgaag
     7081 agtacgactg acataaagag ttgatactgt ttttaaagga aaagagtgtg ccataataaa
     7141 aaacaatagt agtattagaa aaggctaatt ttattgagaa ttagcctttt cttttagctt
     7201 tgataggtgt ataataacca tactattttt tatttttcaa aatattagaa taaacaaaag
     7261 tggacaacgt ataaagagaa ctgctaagtc gttgagttca ttagtcccaa aaagattacc
     7321 aaaaatgaag gaggagctat gaagaaaagt tttattcatc aacaagagga gatttccttt
     7381 gttaagaata cgttcactca gtatttgatt gctaagttag atgttgttga agtgcaagga
     7441 cccattttaa gtcgggtcgg ggacggtatg caagataatt tgtccggtac tgaaaatcca
     7501 gtatctgtca atgtcttgaa aattcctaat gcaacctttg aagttgtgca ttcattagca
     7561 aaatggaaac gtcacacctt agcccgtttt gggtttaatg aaggtgaagg ccttgttgtt
     7621 aatatgaagg ctctccgacc tgatgaggat tcacttgacc aaacccattc tgtctatgtt
     7681 gaccaatggg actgggaaaa agtcatccct gatggcaaac gtaatctcgc ttacctcaaa
     7741 gaaaccgttg aaaccattta caaggtcatt cggttaactg aattagctgt agaagctcgt
     7801 tatgatattg aggctgtttt acctaagaaa ataaccttca ttcataccga agaattggta
     7861 gctaaatacc ctgatttgac gcccaaagaa cgtgaaaatg ccattactaa agaatttgga
     7921 gcagtttttt taattggtat tggcggggtt ttacctgacg gtaaaccaca cgatggccgc
     7981 gctcctgact atgatgactg gacaatagaa actgaaaatg gctatcatgg gcttaatggt
     8041 gatattttgg tttggaatga ccaacttggt tcagcctttg aattatcctc aatggggatc
     8101 cgtgtggatg aagaggccct aaaacgtcag gtggaaatga ctggtgacca agaccgctta
     8161 gcctttgatt ggcacaaatc tttgttgaat ggacttttcc ctctaacgat tggtggagga
     8221 atcggtcaat cacgtatggt catgtttttg ttgcgtaaaa aacatattgg agaagttcag
     8281 acctccgttt ggccccaaga agttcgtgat agctatgata atattttata agtaatcaca
     8341 tcattttgct aagttttcca cttgtataag agactttaaa taaatgatca gaaatattga
     8401 aaaaagaaat catttttaag gtttagagct agaaatttgc tataataaat gttatgagag
     8461 ttgtatcagg tgaatttggt gggcgtcctt taaagacgct cgatggaaag ataacacgcc
     8521 ctacttcaga caaagttaga ggtgcgattt ttaatatgat aggaccttac tttaatggtg
     8581 gtcgtgtttt agatttgttt gcaggttcag gtggattagc cattgaggct gtttctcgtg
     8641 ggatgtctgc tgcagttttg gttgagaaga atcgtaaagc gcaagctatt attcaagaca
     8701 atattataat gactaaagct gagaatcggt ttaccttgtt aaaaatggaa gctgagcgag
     8761 ctattgattg cttgactggt cgatttgact tagtcttttt agaccctcct tatgccaaag
     8821 aaacaattgt ggcaactatt gaagctttag cagctaaaaa cttattgagt gaacaggtta
     8881 tggttgtctg tgagacagat aaaacagtct tgttgccaaa agagattgca acgttaggta
     8941 tttggaaaga aaaaatttat ggaattagta aggtaacagt ttatgttaac taaagtagga
     9001 ctttatacag ggtcatttga tcctgttaca aacggtcatc tcgatattgt taaacgggca
     9061 agtggcctat ttgatcaaat atatgttggg atttttgata atcctaccaa aaaaagctat
     9121 tttaaactag aagttcgtaa agcaatgctt actcaagctc tggctgattt tacaaatgta
     9181 attgtagtaa cttcgcacga acgtttagct attgatgtag ctaaagaatt acgagtaact
     9241 cacttgatta gaggcttgcg aaatgcaact gactttgagt atgaagaaaa tttggaatat
     9301 tttaatcacc ttttagctcc aaatattgaa accgtctatt tgatatcaag aaataaatgg
     9361 caggccctta gctctagtcg tgtgagagag ctaattcatt ttcagtcttc cttagaaggt
     9421 ttggttcctc agtcggttat tgctcaagtg gagaaaatga atgaaaagac ttaaaaaaat
     9481 caaatggtgg ttagtgggtc tgctagcttt aatctctttg ttgctagcgt tattttttcc
     9541 gctaccttat tatattgaaa tgcctggagg cgcttacgat attcggactg tcttacaagt
     9601 caatggcaaa gaagacaaac gaaaaggagc ttaccagttt gttgcagtgg gcattagtcg
     9661 tgccagcctc gctcagctat tatatgcttg gctgacaccg tttactgaaa ttagtacagc
     9721 agaagataca acaggcggat acagcgatgc tgatttcctt cgaattaatc aattttacat
     9781 ggaaacatca caaaatgcag ctatttatca agctttatcc ttagctggaa aaccagttac
     9841 attagattat aaaggcgtat atgttttaga cgtaaacaac gaatctactt ttaaaggaac
     9901 gctacactta gcagatactg taacaggtgt aaatggtaaa cagtttacta gttcagcaga
     9961 acttattgac tatgtttctc acctaaaact aggggatgaa gttacggttc agtttacgag
    10021 tgataataag cctaaaaaag gagttggccg tattatcaaa ctgaaaaatg ggaaaaatgg
    10081 gattggcatt gccttgactg atcatacaag tgtcaattca gaagacacag tgatctttag
    10141 tactaaagga gtaggaggac ctagtgctgg tctaatgttt actcttgata tatatgatca
    10201 aataactaaa gaagatttac gcaagggccg tacaattgca ggtacaggaa ctattggcaa
    10261 ggatggcgaa gtaggagata ttggtggtgc aggtcttaaa gtagttgcag cagctgaagc
    10321 tggtgcagat atattttttg ttccgaataa tcctgttgat aaggaaatta aaaaagttaa
    10381 tccaaatgct ataagtaatt acgaagaagc caaacgggca gccaaacgac taaagaccaa
    10441 aatgaagatt gttcctgtta cgactgttca agaggcactg gtttatcttc gcaaataaaa
    10501 taactatgaa tgtattatat tcaattatat tcacgctatt aactcataaa aaacggttga
    10561 accagataga cagatccttg accagtcttt tgggttcaat cattttttac ataaaacata
    10621 tctaacttga cagcgtaaaa aagatgttat aaaagtctag tggtaaaaag gcaatagaga
    10681 attgagtaaa ctttagtcga ttatctggaa atagagcata ctaaaaatac ctagtgaaaa
    10741 ttgatttttt tcactagctc atccaagaac ttgcgcagat aatcatgagt ccattccatg
    10801 actctattat tctggaaagc cttgcaatag acaagttaac gttataacaa ctaaattaaa
    10861 aacttgagat tgaaaaatcc ccataaactt attttacaag gaggtaaggc tatggtaacc
    10921 attaaacaag ttgctgaaga agcaggtgtt tctagatcaa cagtctccag gtatatttct
    10981 caaaaaggat atgtatctga tgatgcaagg cataaaatca aagcagcgat agcaaaatta
    11041 cattacactc caaatgtctt ggcgcagtca ttgaagacga aaaaaaatca actagtcggt
    11101 ttattattac cagacatttc caatcctttt tttccgaggt tagcaagagg agcagaagaa
    11161 tatttaaaag aaaaggggta tcgggttatg ctaggaaata tttcagacag cgaagctctt
    11221 gaagaagaat acgtccatgt ccttcttcaa agcaatgctg ctggcattat tactacccat
    11281 gactttacaa agcggtatcc tactcttgct attccagttg tagtggtaga tcgtgttgac
    11341 caagagaccc agtacggtgt cttttcagat aatagggcag ggggcttatt ggcggctcag
    11401 actgtctggc aagcaggggc aaaagaagtt ttgttaataa gaggtccgct ggataatgct
    11461 gaaaacatta atgagcggtt tgaagctagt ttttcttacc ttcaaaaaca agacgtgact
    11521 atgtatgtgt gtgatagtca gaattttgat tttgaaagta ttcagctaga agctagttac
    11581 aacctcaagt gttacccaac aatagacagt attatagcac cttctgatat ccatgctatt
    11641 gcttatattc atgaactgca ttctcaaggt aaaaagattc ctcaagatgt tcaaataata
    11701 ggttatgatg acattttaat gagtcaattt atttatcctt ctttatcgac tattcatcaa
    11761 tcctcttatt tgatgggccg ttatgccgcc gaattagttt atactattgc tagtcaatta
    11821 actgtgaaag caaatcggat taaattgcct gttcactacg ttgagcgaga aacaataagg
    11881 aaaagataag taataatatt agtccagatt ttagcaggta tgatgaagat ttattgggat
    11941 ttaccttcta ctttaaaaga agttatctgt cattactttc atcgctatca gtcaaaatgc
    12001 attcttatgc aactcttaac cttaagctta atgtcttttt gataacatag aggaatgtta
    12061 cacgatgatg atgcaataaa gcctaaatat agtaattgtc gtgattttat agctagtgag
    12121 taatgagata gcaagtctct catttactta caaaagtcaa aaaatagtgt ataatggttg
    12181 agttacagat aacactgcaa aaaagataac aagtgtccat aattatctaa gactataaag
    12241 gcgatataga cagatataaa aaagatgacg aatcagttat cactggacaa ttaaccgatt
    12301 tagttacaac taatggattt ttcagaaagg tgtcaaatga aaaaagaaat ttcgccagaa
    12361 atgtacaact ataataaatt tccaggtccc aaatttattc attttgaaga gcaagttaag
    12421 gctgaaggca ttgatttgtt actcttagaa gatgttaaga acgcttttga tacgactagc
    12481 tttggtcaac gttatacaga agttctccta aagtatgact atattgttgg cgattgggga
    12541 aatgaacagc ttcgtcttaa agggttttat aaggatagtg atgatatcaa gaaaacgaat
    12601 cgcatttcac gtttagaaga ttatattaaa gaattttgca attttggttg tgcttatttt
    12661 gttttagaaa atcttcatcc acaagatatt aaatttgaag aggagcgcca accaagacga
    12721 aagaaatcac ctaaatcaaa atcaaatcgt cgcaagccaa actattcaaa tcagcagccc
    12781 gcaacaccta agagtaaatc gaagcggata tcaaaagaaa agcaacctga aaaccaagcg
    12841 tttaccagtc aaaaacgtcg aagtaatact aagcataaag aaaagtcaaa acgtaatcag
    12901 actagtcaac ttaataccaa aattagtcat tttatcatca gaaagaaaga taaataatcc
    12961 atgaaaccat cgatttatag cttaacacgc gatgaactga tcgcgtgggc agttgaacgc
    13021 ggccaaaaac agtttagagc tactcaaatt tgggattggc tttataaaaa aagagttcaa
    13081 tcttttgagg agatgacgaa tatttctaaa gattttgttt ctattttaaa tgatagtttc
    13141 tgtgtcaatc ctttaaaaca gcgagttgta caagagtcag ctgatggtac agtaaaatat
    13201 ttatttgaac tgcccgatgg tatgttaatt gaaacagttt taatgcgtca acattatggt
    13261 cattctgttt gtgtgacgac tcaagttggc tgtaacattg gctgtacttt ttgtgctagt
    13321 ggattgatca aaaagcaacg tgatctaaac agtggggaaa ttacagctca aatcatgtta
    13381 gtccaaaaat attttgacga tagaaagcaa ggtgagcggg ttagccatgt tgtcgtaatg
    13441 ggcattggtg aaccttttga taattacaaa aatgtcatgt gctttcttcg cgtcatcaac
    13501 gatgataatg gcttagcaat tggtgcccgt catattacag tctctacctc agggttagct
    13561 cacaagattc gggattttgc aaacgaggga gtacaggtta atttagcagt ctcgttgcat
    13621 gcaccaaata atgatttacg ttcaagtatt atgcgagtaa atcgctcttt tccgcttgaa
    13681 aagctctttt cagctataga atactatatt gaaaaaacga atcgtcgtgt cacttttgaa
    13741 tacattatgc taaatgaagt taacgatagc attaagcaag ctcaagaact agcagactta
    13801 actaaaacta ttcgtaagtt atcttatgtt aacttgattc cgtataatcc tgtttcagaa
    13861 catgatcagt atagtagaag tcctaaagag cgagttctag cgttttatga tgtgctaaag
    13921 aaaaatggag ttaactgtgt ggtgcgtcaa gagcacggaa cagatattga tgcagcctgt
    13981 ggccagttac gttctaaaac gatgaaaaaa gatcgcgaaa aggttacagc gacaaaataa
    14041 agcccaaaaa atatctttga ttgacaatgc ttgatgacaa aatattccta gtcactaaaa
    14101 tgactaggtt ttttatctgg cctaaaaatg ctctagaagc acaatccaaa ataatccaaa
    14161 actaagataa ggaataaaag gtatgcgctt gatgcctaat agtaagcaag cagtaatacc
    14221 tgctaaacta gcaagttgaa ttagccaaat caacgacatt agatccaata ctaaagctaa
    14281 gctagcaagg tagaaaaaat cgcctgctcc aattgaaaaa ggtcttaaat gagctaataa
    14341 acctagtagc agtaatatca atgataaata attgatcgaa taaaacagga gtagacttac
    14401 aaagctaaaa agccacaaga taaaagggta ttcttgagaa cgccaatcaa ataaactaaa
    14461 taataaagaa aagagtaaca agtaacagta actagcacta acccaatgta ccatactagc
    14521 ccataagata attattagac ttatctctaa gctaaagaag attttttggc tagttataaa
    14581 atggttttgg aactgccgaa aaacgcgttt ggcaaaagtt agttggtcac aaacaatgac
    14641 agtctgttta cttagctgtt cttgaccatt atcaggaaaa taaagtagta aacagtaaaa
    14701 aagatgggtc aataagatgc ccgaacatat actaaaaaaa gctatcatac ttatttattc
    14761 gaaaagaaat caaatacttg caatctttcc ttaatcattg tagaatatag gtataaaacg
    14821 ataatgattc taattaagtg tctaatcatc caattaggat tattccgtta ttgtcgaata
    14881 ggattaggtc cttaaccctt tcttatgttt atcacgttag ggttagttcc ccctccattc
    14941 ttgcccttta agctgaaaag taaggagatg ttattatgac aaacacactc gttgaaaata
    15001 tttatgcttc agtaactcac aatatttcta aaaaagaagc atcaaaaaat gaaaaaacta
    15061 aagctgtttt aaaccaagct gtcgctgact tatctgtggc tgcatctatt gtgcaccaag
    15121 tacactggta tatgcgtggt ccaggtttct tgtaccttca ccccaaaatg gatgaattac
    15181 ttgatagctt gaatgctaat ttagatgaaa tgagcgagcg tttgatcact attggcggag
    15241 cgccttattc taccctagct gagttttcta aacactctaa attggacgaa gcaaaaggta
    15301 cttacgataa aacagttgct cagcatttag caagattggt cgaagtttac ctttacctca
    15361 gcagccttta ccaagttggt ttggatatta ccgatgaaga aggcgatgct ggaacaaacg
    15421 atttgtttac agcagctaag acagaggctg aaaaaaccat ttggatgctc caagcagagc
    15481 gtggacaagg cccagcactc taattgatta tgccttagga taaaagaagt caatgataaa
    15541 attggcttct tttttatgga atcatcgatt cattttcaga aacatagaaa gcgattccat
    15601 acttgtcttg aaatctgccg tagaatttgc taaaatctac ttatatgaaa acactatatg
    15661 atgtgcaaca attgctaaaa aactttggca tttttgttta ccttggcaaa cgtctttatg
    15721 atattgaaat gatgaagatt gaacttcagc gtctctatga tagcggctta ttggataaga
    15781 gggattactt aaatgcggag ttaattttgc gacgtgagca tagattagaa ttggaaaaag
    15841 aaggatagac aaatgagtca aaaattactg gggattgatt taggtggtac caccattaaa
    15901 tttggaattt taacagcagc aggagaagtc caagaaaaat gggcaattga gactaatatt
    15961 ttagaaggag gcaaacatat tgttcctgat atcatcgctt ccatcaaaca tcgcttagac
    16021 ttgtatggtc taagcagtgc tgattttgtg ggaattggta tgggatcacc aggagcggtt
    16081 gaccgtgata ctaatacagt tactggggca ttcaacctta attggaaaga aacccaagaa
    16141 gtcggttccg ttgttgaaaa agaattgggc attccttttg ccattgacaa tgatgccaat
    16201 gtggctgccc ttggtgaacg ttgggtaggt gctggtgaaa ataacccaga tgtcgtcttc
    16261 atgacacttg gaacaggtgt cggtggaggc attattgctg atggtaactt gattcatggt
    16321 gttgcaggag caggtggtga aatcggccac atgattgttg agccagaaaa tggctttgct
    16381 tgtacttgtg gctcacacgg ctgtttggaa acagtagctt cagcaacagg agttgtcaaa
    16441 gtggcacgtt tactggcaga agcctacgaa ggggattcag ccatcaaagc agctattgac
    16501 aatggtgaag gtgttaccag taaagacatt ttcatggcgg ctgaagcagg ggattccttt
    16561 gctgattctg ttgtggaaaa ggttggttac taccttggcc ttgcttcagc aaatatttcc
    16621 aatatcttga atccagactc agtggttatc ggtgggggtg tgtcagcagc aggagaattt
    16681 ctacgctcac gtattgaaaa atactttgtg accttcactt tcccacaagt gaggtattca
    16741 actaaaatta agattgcaga gcttggcaat gatgctggaa ttatcggtgc agctagcctt
    16801 gctcgacaat ttatcacaaa ataggagggg gatatgtctc caatcacact tatcttatgg
    16861 ttacttcttg tcggcattgt tggttattat acatggaact atttctcttt tcgaaaaatg
    16921 gcaaagcagg ttgataacga gacttttaaa gacgtgatgc gtcaaggtca attgattgat
    16981 ttacgagagc cagcggcttt tagaactaag catattttag gagctcgaaa ttttccagcg
    17041 caacaatttg atgctgctat caaaggtctt cgcaaggaca aacctgttct tatttacgaa
    17101 aatatgcgtc cccagtaccg tgtgcctgcg gtcaaaaaac ttaaaaaagc tggctttgaa
    17161 gacgtttatg tcttaaaaga cggtattgat tattgggatg gcaaagttaa acaaacaacc
    17221 tagttaagag taacgtggag ttaaggggaa taaaggtagt cactgtctca aaaaccttaa
    17281 ttcctttttt tgctgtatcc agacttgctg aaagtctgaa aacatttaca attgattaaa
    17341 accagttttt taaaacattt tgtgttatac ttatctagtt aaaatatatt tacttagagg
    17401 aacaaatgac taacttaaga aacgatatcc gtaacgtagc gattattgcc cacgttgacc
    17461 acggaaaaac aacacttgta gatgaattat taaaacaatc ccatactctt gatgagcgta
    17521 aagagcttca agagcgtgcc atggattcca atgaccttga aaaagaacgt gggattacaa
    17581 tccttgcgaa aaatacggca gtagcctata acgatgttcg tattaacatc atggataccc
    17641 caggacacgc ggacttcggt ggtgaagttg aacgtatcat gaaaatggtt gacggggttg
    17701 ttcttgttgt ggatgcctac gaaggaacaa tgccccagac gcgtttcgta ttgaaaaaag
    17761 cacttgagca aaaccttatc ccgatcgttg tggtgaacaa gattgacaaa ccttcagctc
    17821 gtccagcaga agttgtagat gaagtgcttg aattattcat cgaacttggt gccgatgatg
    17881 agcaattgga attcccagtt gtttacgcat cagctattaa tggcacatca tcattatcag
    17941 atgaccctgc tgaccaagag catactatgg caccgatctt tgatacgatc attgatcata
    18001 ttccagcgcc agttgataat tcagatgagc ctttgcaatt ccaagtgtca cttttggact
    18061 acaacgattt cgtaggtcgt atcggtatcg gtcgtgtttt ccgtggtact gttaaagttg
    18121 gtgaccaagt aactctttca aaacttgatg gtaccactaa aaacttccgt gttacaaaac
    18181 tgtttggttt cttcggattg gaacgtcgtg aaattcaaga agctaaagca ggtgacttga
    18241 ttgctgtttc aggtatggaa gatatctttg ttggagaaac cattacacca actgactgtg
    18301 tggaagctct gccaattctt cgtattgatg agccaacact tcagatgact ttcttggtca
    18361 ataactctcc ttttgcaggt cgtgaaggta aatggatcac gtcacgtaag gttgaagaac
    18421 gtcttttagc agaattgcaa acagacgtgt cacttcgtgt tgacccaaca gattcgccag
    18481 ataaatggac ggtttcaggg cgtggagaat tgcatttatc tatcctcatt gaaaccatgc
    18541 gccgtgaagg ctatgaactt caagtatcac gtccagaagt tatcatcaaa gaaattgatg
    18601 gtgtcaaatg tgaaccgttt gagcgtgttc aaattgatac accagaagaa tatcagggtg
    18661 caatcatcca gtctctttca gaacgtaaag gggatatgct tgatatgcag atggttggta
    18721 atggtcaaac gcgtttgatt ttcttgattc ctgcacgtgg tttgattggt tattcaacag
    18781 agtttctttc aatgacacgt ggatatggta tcatgaatca tacttttgat cagtatctac
    18841 cggttgttca aggagaaatc ggtggccgtc atcgtggtgc cttggtttct attgaaaatg
    18901 ggaaagcaac gacatattca atcatgcgta ttgaagaacg tggaactatc tttgtcaacc
    18961 caggtacaga agtttacgaa gggatgattg ttggtgaaaa ctcacgcgat aacgaccttg
    19021 gtgttaacat tacaacagct aagcaaatga caaatgtccg ttcagcgact aaagatcaaa
    19081 ctgcagttat caagacgcct cgtatcctaa cgcttgaaga atcattagag ttcttgaatg
    19141 acgacgaata catggaagta acgccagaat ctatccgctt gcgtaaacaa atcttgaata
    19201 aagctgcgcg tgataaagct aataaaaaga aaaaatcagc cgaatagctt ttgaagttaa
    19261 actaactaaa taaaatagca aaaagatatt taagaaaagt cattttttaa aggtcttttt
    19321 gcgtttacaa gttcctatgg aatataaacc aaaataaagg aggacggaat gttttacctt
    19381 attatggctg tctcgattat atcttattat ctatacatgg ctcctaaaag tgtccgtaac
    19441 acccttggga tgattggttt agttggcttg gttgctctgc ttattgtttt agcgggcttg
    19501 agttttatca aaatcatgca aacccctcct gaatttttta ttgggatggg aatggtggca
    19561 ttgggctatt ttgctttaaa agatgtgcgt aaaatgacca aaaaaccgag agttaaataa
    19621 aaatacttaa agattgatga ttttggtttt tatacgataa aaggactgat ttgttttaga
    19681 caatatcagt ccttttttaa tagttcattt tttctgaaag aaagctttta gccgattttc
    19741 attgagtgtg caactaaaaa aagatgcttg gtagtgacag ttaagacctc tgactagtat
    19801 tttatcttat tttacttaaa aaaacgtacc aataatctca caaatatggg catgatattt
    19861 gtatattgga aacggattct aattctaaac tcaagaacgg tatttttaaa atgttgaaaa
    19921 agcatctaaa taaaggtaaa atagaaatca aatagaatgg atagtgtgag cttagatgaa
    19981 agtgataagt aattttcaaa acaaaaaaat attaatattg gggttagcca aatcgggcga
    20041 agcagcagca aaattattga ccaaacttgg tgctttagtg actgttaatg atagtaaacc
    20101 atttgaccaa aatccagcgg cacaagcctt gttggaagag gggattaagg tcatttgtgg
    20161 tagccaccca gtagaattat tagatgagga ctttgagtac atggttaaaa accctgggat
    20221 tccttatgat aatcctatgg ttaaacgcgc ccttgcaaag gaaattccca tcttgactga
    20281 agtagaattg gcttatttcg tatctgaagc gcctattatc gggattacag gatcaaacgg
    20341 gaagacaacc acaacgacaa tgattgccga tgttttgaat gctggcgggc aatctgcact
    20401 tttatctgga aacattggtt atcctgcttc aaaagttgtt caaaaagcaa ttgctggtga
    20461 tactttggtg atggaattgt cctcttttca attagtggga gtgaatgctt ttcgccctca
    20521 tattgctgtc atcactaatt taatgccgac tcatctggac tatcatggca gttttgagga
    20581 ttatgttgct gctaaatgga tgattcaagc tcagatgaca gaatcagact accttatttt
    20641 aaatgctaat caagagattt cagcaactct agctaagacc acccaagcaa cagtgattcc
    20701 tttttcaact caaaaagtgg ttgatggagc ttatctgaag gatggaatac tctattttaa
    20761 agaacaagcg attatagctg caactgactt aggtgtccca ggtagccaca acattgaaaa
    20821 tgccctagca actattgcag ttgccaagtt atctggtatt gctgatgata ttattgccca
    20881 gtgcctttca cattttggag gcgttaaaca tcgtttgcaa cgggttggtc aaatcaaaga
    20941 tattaccttc tacaatgaca gtaagtcaac caatatttta gccactcaaa aagctttatc
    21001 aggttttgat aacagtcgct tgattttgat tgctggcggt ctagatcgtg gcaatgaatt
    21061 tgacgatttg gtgccagacc ttttaggact taagcagatg attattttgg gagaatccgc
    21121 agagcgtatg aagcgagctg ctaacaaagc agaggtctct tatcttgaag ctagaaatgt
    21181 ggcagaagca acagagcttg cttttaagct ggcccaaaca ggcgatacta tcttgcttag
    21241 cccagccaat gctagctggg atatgtatcc taattttgag gttcgtgggg atgaattttt
    21301 ggcaaccttt gattgtttaa gaggagatgc ctaatgccta agaagatttt atttacaggt
    21361 ggtggaactg taggtcatgt caccttgaac ctcattctca taccaaaatt tatcaaggac
    21421 ggttgggaag tacattatat tggtgataaa aatggcattg aacatacaga aattgaaaag
    21481 tcaggccttg acgtgacctt tcatgctatc gcgacaggca agcttagacg ctatttttca
    21541 tggcaaaatc tagctgatgt ttttaaggtt gcacttggcc tcctacagtc tctctttatt
    21601 gttgccaagc ttcgccctca agcccttttt tccaaaggtg gttttgtctc agtaccgcca
    21661 gttgtggctg ctaaattgct tggtaaacca gtctttattc atgaatcaga tcggtcaatg
    21721 ggactagcaa acaagattgc ctacaaattt gcaactacca tgtataccac ttttgagcag
    21781 gaagaccagt tgtctaaagt taaacacctt ggagcggtga caaaggtttt caaagatgcc
    21841 aaccaaatgc ctgaatcaac tcagttagag gcggtgaaag agtattttag tagagaccta
    21901 aaaaccctct tgtttattgg tggttcggca ggggcgcatg tgtttaatca gtttattagt
    21961 gatcatccag aattgaagca acgttataat atcatcaata ttacaggaga ccctcacctt
    22021 aatgaattga gttctcatct gtatcgagta gattatgtta ccgatctcta ccaacctttg
    22081 atggcgatgg ctgaccttgt agtgacaaga gggggctcta atacactttt tgagctactg
    22141 gcaatggcta agctacacct catcgttcct cttggtaaag aagctagccg tggcgatcag
    22201 ttagaaaatg ccacttattt tgagaagagg ggctacgcta aacaattaca ggaacctgat
    22261 ttaactttgc ataattttga tcaggcaatg gctgatttgt ttgaacatca ggctgattat
    22321 gaggctacta tgttggcaac taaggagatt cagtcaccgg acttctttta tgaccttttg
    22381 agagctgata ttagctccgc gattaaggag aagtaaatgg caaaagataa agagaaacaa
    22441 agtgatgaca agctcgtttt gacagagtgg caaaagcgta acattgaatt tttaaagaaa
    22501 aagaagcagc aagctgagga agaaaaaaaa ctcaaagaga aattattgag tgataaaaaa
    22561 gcgcagcagc aagctcaaaa tgcttctgaa gcggttgagc ttaaaactga tgagaaaact
    22621 gatagtcagg aaattgagtc agaaacgacg tcaaaaccta aaaaaaccaa aaaagttaga
    22681 caacccaagg aaaaaagcgc gacacaaatc gcttttcaaa aatcctttcc tgttcttttg
    22741 ggggcgctct tactcatggc ggtgtctatt tttatgatca ctccttatag caaaaagaaa
    22801 gagttttctg taagaggaaa ccatcaaacg aaccttgacg aattaatcaa agctagcaaa
    22861 gtcaaagcat ctgactattg gttaacgctg ttaacttcgc ctggtcagta tgaacgaccg
    22921 attcttcgta ctattccatg ggtgaaatct gtacatctct cttaccaatt tcctaatcac
    22981 tttctattta acgttattga atttgaaatc atcgcttatg cacaagttga aaacggtttt
    23041 cagcctattt tggagaatgg aaaacgtgtg gacaaggtca gggcatcaga actaccgaaa
    23101 tctttcttga ttcttaattt aaaagatgag aaagcgatcc aacagttagt taagcaatta
    23161 acgacattac ctaaaaaatt agtcaagaat atcaagtcag tgtctcttgc aaattccaaa
    23221 acgacagcgg atttactact tattgaaatg catgacggta atgtagttag agtaccgcag
    23281 tcacaactca cattgaaact tccctattat caaaaattga aaaaaaacct tgaaaatgat
    23341 agtatagtgg atatggaagt gggaatttat actacaacac aggagattga aaatcaacct
    23401 gaagttcctc ttacgcctga acaaaacgca gctgataaag aaggagataa gcctggtgaa
    23461 catcaggaac agacagacaa tgattcagaa acgccagcaa atcagagtag tcctcagcaa
    23521 acaccaccat ccccggaaac ggtcctcgaa caggcccatg gctagctaat atctaagttg
    23581 aaaaagcaat gaaaacgtta gaaattcaac gattctaacc cataatgaat tgcctaaaaa
    23641 aaattaagtt tatataacaa aaaacgtaaa atgataacat tttacgtttt tttatggtat
    23701 aatattttct gaatgattct gttttttagc agtttttaga atagcaaaag tttggaaagt
    23761 aagtgaggtc aagtgaatgg ctagaaatgg cttttttact ggtttggaca ttggaacaag
    23821 ctcgataaaa gttttagtag cagaatttat ttctggtgag atgaacgtca ttggtgttag
    23881 taatgttcca agtaccggcg taaaagatgg cataataatc gatatagagg cagctgcgac
    23941 tgccatcaaa actgcggtag aacaagcaga agaaaaagca gggatgacaa ttgaaaaggt
    24001 taatgttggg ctaccggcaa accttcttca aattgaacca acacaaggaa tgattcctgt
    24061 cccaagtgag tctaaagaga taaaagatga ggatgttgat agcgttgtta aatcggcttt
    24121 aacaaaaagt atcacaccag aacgagaggt tatctcttta gttccagaag agttcattgt
    24181 ggatggcttt cagggcattc gagatccacg tggtatgatg gggattagat tagagatgcg
    24241 cgggcttatt tatactggac caagcaccat tttacataat ctgcgtaaaa cggtagaaag
    24301 agcaggcatt aaagttgaaa acatcattat ttctccgtta gctatggcta aaaccatttt
    24361 aaacgaaggt gagcgcgagt ttggagctac tgtaattgat atgggaggtg gacagacaac
    24421 tgtcgcttct atgcgagcac aagaattgca gtataccaat atatatgctg aaggcggcga
    24481 atacattact aaagatatat caaaagtatt aaaaacgtct ttggctattg cagaagcact
    24541 taagtttaat tttggtcaag cggagatatc agaagctagt ataactgaaa cagtaaaagt
    24601 tgatgtggta ggtagtgaag agcctgttga ggtaactgaa cgttatttat ctgaaattat
    24661 ttcagcgcgt attcgtcata ttttagatcg tgtgaagcaa gatttggaaa gaggtcgttt
    24721 actagactta ccaggaggca ttgttttgat tggtggcggt gcaatcatgc ctggagtggt
    24781 agaaattgca caagaaatct ttggagtaac tgtaaagctc catgttccaa atcaagtcgg
    24841 tattagaaat ccaatgtttt caaacgttat cagtttggta gaatatgttg gtatgatgtc
    24901 tgaagtagac gttttagcac aaactgcagt ttcaggagaa gaacttttgc gacgcaagcc
    24961 tatcgatttc agtggtcaag aatcttattt accagattat gatgattcaa gaagaccaga
    25021 atcgaccatt ggctatgaac aacaagcgtc acaaacagca tatgattcac aagttccgag
    25081 tgatcctaaa caaaaaattt cagaacgtgt tcgtggcata tttgggagta tgtttgatta
    25141 aaagtaataa agtgaggaga taaaatggca ttttcatttg atactgcatc aattcaaggt
    25201 gcaattataa aagtaattgg agtcggcgga ggtggcggaa atgccattaa tcgtatgatt
    25261 gatgaaggtg ttgctggtgt cgagttcatc gcagcaaata cagacattca ggcattaagc
    25321 tcatcaaaag ctgaaacggt tattcaacta ggccctaaat taactcgtgg acttggtgct
    25381 ggaggacaac ctgaagtagg acgtaaagct gctgaagaaa gcgaagaaat tttaacagaa
    25441 gctcttacag gagcggacat ggtatttatt actgccggta tgggtggtgg ctctgggaca
    25501 ggggctgcac cggttattgc tcgtatcgct aaaagtttgg gagccttgac agtagctgtt
    25561 gttactcgcc cgtttggttt tgaaggtaac aaacgtggta attttgctat tgaaggtatc
    25621 gaagaactcc gtgaacaagt tgatactttg ttaattattt caaataataa ccttcttgag
    25681 attgttgata aaaagacacc tttattagaa gcacttagtg aagctgataa tgttttacgt
    25741 cagggagttc aagggataac cgacttaatt actagtcctg gccttatcaa tctcgatttt
    25801 gccgacgtga aaacagttat ggcaaataaa gggaatgcct tgatggggat tgggattggt
    25861 tctggagaag agcgcattgt tgaggcggcg cgtaaggcaa tctattcacc cctattagaa
    25921 acgactattg atggtgcaca agacgttatt gtgaacgtta caggaggtct cgacatgaca
    25981 cttacagaag ctgaagaagc ctctgaaatt gttgggcaag ctgctggtca aggcgttaac
    26041 atttggttag gaacatctat tgatgatact atgaaagatg acatccgtgt gactgttgta
    26101 gcaactggag tgcgccaaga aaaagctgaa caagtttcag gttttcgtca gcctaggact
    26161 tttacccaaa ccaacgcgca gcaagtagcg ggtgcacaat atgcatcaga tcaagcaaaa
    26221 cagtcggttc aaccagggtt tgatcgtcgc tcaaattttg attttgacat gggggagtct
    26281 cgcgagatac caagtgcaca aaaggtaatt tctaatcata atcaaaatca aggttcagct
    26341 tttggaaatt gggatttgag acgtgataat atttctcgtc caacagaagg tgaattggat
    26401 aaccatctta atatgtcaac gttctcagct aacgatgaca gtgatgatga attagaaacg
    26461 cctccattct ttaaaaaccg ttaataatgg atttactgac aaataaaaag aaaatttttg
    26521 agactatccg cttatctaca gaggcagcaa ataggactaa tgatagtgtt tcagttattg
    26581 ctgtaacaaa atatgtggat agtacaattg caggtcagct tatcgaatca ggaattgagc
    26641 acattgccga aaaccgtgtt gataaatttc ttgaaaagta tgatgcgtta aagtatatgc
    26701 cagtaaagtg gcatttaatc ggtaccttac aacgtcgtaa ggtcaaggaa gttatcaatt
    26761 atgttgatta ttttcacgct ctagattctg tgagattagc tttggaaatc aacaagagag
    26821 ctgaccatcc tgtgaagtgt tttctacaag ttaatatttc taaagaagag agtaaacatg
    26881 gttttaacat ttctgagatt gatgaagcga ttgaagaaat aggtaagatg gagaagatac
    26941 agttagttgg tttaatgact atggcaccag caaatgccag taaagaaagt attataacta
    27001 tttttcgaca agcaaatcaa ttaagaaaaa acttgcagtt aaaaaaaaga aagaatatgc
    27061 cttttacaga attgagcatg ggcatgagta acgattatcc aattgctatt caagaaggct
    27121 caacttttat tcggattggt agagctttct ttcactaatg gagaataaga tggcttttaa
    27181 agatacattt aacaagatga tttcttattt tgacacggat gaggttaacg aagttgaaga
    27241 agatgttgca gcatcaactg ataacgttat tccaagatca caacaatcag tcagagcaag
    27301 tagtcatcca aaacaagaac ctagaaacaa tcacgtacaa caagatcatc aagcgagatc
    27361 ccaagaacag acaaggtcac aaatgcatcc aaaacatggt acttctgaac gctattatca
    27421 gcagtctcag ccaaaagaag gccatgaaat ggttgacaga agaaaacgga tgagcacttc
    27481 tggtattgca aatcgccgtg agcagtatca acaatcaact tgttcagatc aaacaaccat
    27541 tgccttaaag tatcctcgta aatatgagga tgctcaagaa attgtggatc ttttaatagt
    27601 taatgaatgc gttttgattg attttcagtt tatgctagat gctcaggcta gacggtgttt
    27661 agattttatt gatggtgcta gtaaagtgct ctatggtagc ttacaaaagg tcggctcttc
    27721 aatgtactta ctggctccgt caaatgtatc cgtcaatata gaagaaatga ctatcccaca
    27781 tactacacaa gatattggct ttgattttga tatgaaaagg cggtaaataa atgatattaa
    27841 tactatctat tcttcttcgt ctgatcaaag tttacactta tttattgatt gcttacgcac
    27901 taatgtcatg gtttcctggg gcatacgatt caaaaattgg gcgtttgatt agtggtatcg
    27961 ttgaaccaat tttaaaacct tttagagcat ttaatttaca atttgccggt cttgacttca
    28021 ctatttttgt cgtcattatt agtttgaatt ttttagctca agttttggtc cgtgtgttta
    28081 tttaatgatt agtcatagta agatttatca gcattttcac caagaagaat atccttttat
    28141 tgatagaatg tctgatatga ttaatagagt tgaagattac tatcttttag aagttactga
    28201 gtttttaaat cctagagaag tgatgatttt aaaaagtttg attgctttaa cagatctaaa
    28261 aatgttcgta tcaacagatt actacctaag cgaatatggt cgtgtcatta ttgcacctgg
    28321 ttactatgac ttagaacaaa gtgattttca aatagcttta gtagagataa gttatcaggc
    28381 aaagtttaat cagttgacac atagtcaaat tttaggaact ttaattaatg aattaggagt
    28441 aaagcgaaat ttatttggag atgtttttgt tgaaatggga tacgcccagc tcatgattaa
    28501 gcgggagtta ttggattatt ttttaggaac aattactaaa atagctaaaa ctagtgtgaa
    28561 attaagagaa gttaactttg atcagttaat taggtctatt gataacagcc agcccctgga
    28621 tattctagtt tctagttttc gattagatgg tgtagttgct actatcttaa aaaaatctcg
    28681 aacgcaagtt atagcattaa ttgaagcaaa taagattaag gtaaactatc gactcgctaa
    28741 taaagcttca gataatctag tcatagggga tatggtgagt atcagaggtc acgggcgttt
    28801 tactctttta gcagataatg gagtgaccaa acatggccaa caaaaaataa cactaagtaa
    28861 aatgatacat aaataaggag atacaatggc acttacaacg ctagaaatta aagataaaac
    28921 ttttaagaca aaattccgag gatactgtga agaagaagtc aatgaattcc ttgatattgt
    28981 tgttgatgat tacgaagctc ttgtacgtaa aaatcgtgat aacgaagcaa gaattaaaga
    29041 tcttgaagaa aaattatctt actttgatga aatgaaagag tcacttagcc agtctgtaat
    29101 cttagctcaa gaaacagctg aaaaagtgaa agcaacggct aatgcggaag caacaaactt
    29161 ggttagtaaa gcgacttatg atgctcagca tttattagat gaatctaaag ctaaagccaa
    29221 tcaaatgttg cgtgatgcaa ctgatgaggc taagcgagtt gcgattgaaa cagaagaatt
    29281 aaagcgtcaa acacgtgtgt tccaccaacg tttaatctca tctattgagt cacaattaag
    29341 cttatcaaat tcacctgaat gggatgaact gctacaaccg actgcaatct atcttcaaaa
    29401 ttctgacgat gcttttaagg aagtcgtgaa gaccgttctt aatgaagaca ttcctgaatc
    29461 tgatgatagt gcctcttttg atgcaacacg tcagtttact ccagaagagt tagaagaatt
    29521 gcaacgtcgt gttgatgaaa gcaataagga gttagaggct taccaacttg actctcaatc
    29581 tgattctacg actgagccag aggtaaatct cagtgaaaca caaacgttta aattaaatat
    29641 ctaaataaag aaaaacaaga tgatttgctt ataatcacag caagcgggag atgatgagag
    29701 tctcgtattc cctaagtatt atcattatca ttttctaaaa ttttcgctga actacagtaa
    29761 gcgaggaggt ttgttcacct tacgagcaaa gagggagcgg taagtcttat gatatattat
    29821 cgctctgaac taaggtggta ccacgagctt tcgtcctttt tgagacgagg cttttttcgt
    29881 tatagtcgca agtttgttta aaaggagttt gaaataatga aattaaaaga gacacttaat
    29941 ctaggaaaaa cagcctttcc aatgcgcgca ggtcttccta ataaagagcc acaatggcaa
    30001 gcagcttggg aacaagcaga gctttacaaa aaacgtcaag aattgaatgc aggtaagcct
    30061 gcctttcatc ttcatgatgg acctccatac gctaacggca atattcacgt tgggcatgcc
    30121 cttaataaaa tttcaaaaga tatcattgtg cgttctaagt ccatgtctgg ctttcaagcc
    30181 ccttatgtac ctggttggga cacacacggc cttccaatcg aacaagtctt ggctaagcaa
    30241 ggaatcaaac gtaaggagat ggatttagca gaataccttg agatgtgtcg tcaatacgct
    30301 ttaagtcagg ttgataaaca gcaagatgat ttcaaacggt taggtgtttc ggcagactgg
    30361 gaaaatcctt atgtcacttt ggacccacag tttgaagctg atcaaattcg tgtttttgga
    30421 gcgatggctg aaaaaggtta catctatcgt ggtgctaaac ctgtttattg gtcatggtct
    30481 tcagaatcgg ccttggcaga agctgaaatt gaataccatg acatcgattc aacctcttta
    30541 tactacgcca ataaagttaa agatggtaaa gacatccttg atactaatac gtatatcgtt
    30601 gtttggacca caacaccatt taccgttaca gcatcacgcg gtttgactgt tggtcctgat
    30661 atggattatc ttgtggtgaa acctgctggt tcagaccgtc aatatgttgt ggcagaaggt
    30721 cttttggata gccttgctgg aaaatttggc tgggaatctt ttgaaacttt agccagccat
    30781 aaaggagctg atttagagta cattgtgaca gaacacccat gggatactga cgtagaagaa
    30841 ttggttatcc ttggtgacca tgttaccctt gagtcaggga cagggattgt ccacacggcg
    30901 ccaggttttg gtgaagatga ctacaatgtt gggacaaaat ataaactgga agttgctgtg
    30961 actgttgatg aacgtggcct aatgatggaa aatgcaggtc cagatttcca cggacaattt
    31021 tataacaagg taacgccgat tgtcattgat aaacttggtg atcttttatt ggcacaagaa
    31081 gtgatcaatc actcttaccc atttgactgg cgaacgaaaa aaccaatcat ctggcgtgct
    31141 gtaccgcaat ggtttgcttc tgtttctgat ttccgtcaag atattttgga tgaaattgaa
    31201 aaaacaacct tccatccatc atggggtgaa acacgccttt acaatatgat tcgtgatcgt
    31261 ggcgactggg ttatttctcg tcaacgtgct tggggagttc cgcttcctat cttctatgcc
    31321 gaagatggca cagctattat gactaaagaa gtgacagatc atgtggctga tttgttccaa
    31381 gaaaatggat caatcatttg gtggcaaaaa gaagctaaag acctattacc agagggcttc
    31441 actcatccag ggtcaccaaa tggcgagttt acaaaagaaa ctgatatcat ggacgtttgg
    31501 tttgactctg gttcttcttg gaatggagtc atgaatgcta gagaaaatct ttcctatcca
    31561 gcggatctct acttagaagg ctctgaccag tatcgtggtt ggttcaattc atccttaatt
    31621 acatctgtgg ctgttaatgg gcatgctcca tataaggcta ttttatcgca aggctttgtt
    31681 cttgatggta agggcgaaaa aatgtctaaa tcaaaaggca atatcatttc tccaaatgat
    31741 gtggctaaac aatatggtgc agatattctc cgtctctggg tagcttctgt ggataccgat
    31801 aatgatgttc gtgtttctat ggagatcctt ggtcaagtct ctgaaactta ccgtaaaatc
    31861 cgtaacaccc ttcgcttctt gattgctaat acatctgatt tcaaccctgc tacggataca
    31921 gtagcttatg cagacttagg agccgttgat aagtacatga caattgtctt taatcagttg
    31981 gtagcaacga ttactgacgc ttatgagcgt tatgacttta tggctattta caaagcagtg
    32041 gtgaactttg ttacggttga tttatcagcc ttctatcttg attttgctaa agacgttgtc
    32101 tatattgaag ctgccaatag cttagaacgt cgtcgcatgc agacagtctt ctatgatatc
    32161 ttggttaaga ttaccaagtt attgacgcca atcttgcctc acaccactga agaaatctgg
    32221 tcttatctag agcatgagtc agaagcattt gttcaattgg cagaaatgcc tgtggcagaa
    32281 accttctcag ctcaagagga tattttagaa gcttggtctg ctttcatgac tttgcgtacc
    32341 caagctcaaa aagctttgga agaagcgcga aatgctaaga ttatcggtaa atcattggaa
    32401 gcccatttga ccatctacgc tagtgaagaa gtgaaaacct tattgactgc tttagatagc
    32461 gatattgctt tgcttttgat cgtgtctcaa ttaaccattg ctgacttggc agatgcgcct
    32521 gcggatgcag tggcatttga aggtgttgcc tttatggtag aacatgccat aggtgaagtt
    32581 tgtgagcgtt cacgccgcat cgacccaact actcgcatgc gttcttacaa tgcatttgtc
    32641 tgtgatcaca gcgctaaaat cattgaagaa aatttcccag aagctgtggc tgaagggttt
    32701 gaagagagtg gcaaataagt cttatcaaga cttgaagtga cactgagtaa gaagacaacc
    32761 atcgggtctt aggacctgat ggttttttag tagagctgat tacgtccatt agccagcttt
    32821 aacgagagac aaagtaggag aaatttagac tactttttta atttctttta agaaaattgc
    32881 tggcttcata taaggactat taagatagag ttcacctttc gctaataaaa aaacttagct
    32941 cttttagaag ggctaagttt tgtctgaata gctggctgct gtttatacag aagtttgaaa
    33001 tgaaatttca ataaggttat tcgtgtgaag tgtttttgat tgtccaggaa taacaatttt
    33061 aggatcaatt ttacgtttta aaaaaaattc gcgaatgata tcaagttcat cctccttgat
    33121 ggcacggtat ttatttgaaa taagtagttc gtaatgtttt ggtgcttggg taaaaatgac
    33181 atctgtattt cctgctgagt atacttcgac taaataggca tcggtgtttt ttagctgatt
    33241 tctgatgagt tctgggtgac tgctagtggt attgatgagt ctcataaatg tcctccttag
    33301 tattcctgta cctattatag cactaattta aagccttagt tagtagaatg atgctttttt
    33361 tgccattcct tgactcccca ttgatggctc tctcgtttta atttagcaat tgcctcgata
    33421 ggagaaaacc aacttaagtt attaaaatct tctaagggct tagaaacggc ttgaaatgcg
    33481 gttacttcat aaagataggc aggatggtag aaatgggtat cacgatggcg agagtagaaa
    33541 tattcatcag cctgaccgta atatgaaccg atagtagcag aaaaaccaag ttcttcaatc
    33601 agttcacgct ctagggcctg aagctgacct tcacctgctt caatttcacc accaggtaaa
    33661 aaccaggaac cattaggagc ttgaacaaga ataatttttg tttgttcgtg attgggaatg
    33721 atagcataga caccgtaacg tgtgacatag tctttatgtg catttttatg tccaaatgtt
    33781 ggaatcatca ttttatttac ctttcctttt tcttcattat actaaatttt tgctaattat
    33841 tcttatcaat ttgtttagtt taataaaaaa ttgatagaaa aagagagagt ctccttatag
    33901 aaactctctt agctaacgtt aatctagaga ctcttcgtta agaaaagaat ctccctcttt
    33961 aacagcttta atcgtgatgt tttcactgtt tgtcatcagt gcacgtaact gtttttcagt
    34021 tgggtgttct aaataatagt ctgtaatggc atcttcgata taatcttgga tagtacgacg
    34081 gagcggccga gcgcccattt taggatcata gcctaaatct actaattttt ctttgacctt
    34141 ttgtgtcaca tcaagatgaa tcccattata gcctaagcgc tcattaacat cttccagcat
    34201 taaatcaacg atatgcagca aatgctcttt agataaagct ttgaattcaa taataccatc
    34261 gaaacgattc ataaactctg ggctgaagaa gttgcttaat tcaccaagga cagaacttgt
    34321 ccgtccttct ctagcagcac caaatccgac agaagcttcg cttttacctg ttccggcatt
    34381 agaggtcatg ataataatgg tgtccttgaa gctgactgtt cgcccttggc cgtctgttaa
    34441 gcgaccgtca tcaagaactt gtaagaacat gtgcatgacg tcaggatggg ctttttccac
    34501 ctcatctaag agaataaggg aataaggatt gcgacgaact tgttcggtta gctgtccagc
    34561 ttcttcatag ccgacataac ctggaggagc cccgactaat ttggcgacag cgtgtttttc
    34621 catgtattcg gacatgtcaa agcgaatcat attgtttgtc gaaccaaaga gttcaatggc
    34681 tagttgttta gacaattcag ttttaccaac cccagtcggt ccaacgaata agaaagaacc
    34741 aatagggcga tttggagttc ctaatcccac acggttacga cgaatagcct tagcgatttt
    34801 atcaacagca tcgtcttgcc cgatcacgtg tgctttcaga tcattggcta agtttacgag
    34861 ttgagactgt tccttttctt ttaagtcccc aactggaata ttagtttttt gctctacaat
    34921 agcttcaatg gttttttcag taatgatggg aatatcttgc tcatcgactt tttgagcctg
    34981 catttctttg tattttgtaa tttgatcgcg gaaataagct gcgcgttcat agtcttcgtc
    35041 tcgagtagct tgcgccttga gattctcagc ttcaataaga tgtttgtcaa tttctttagg
    35101 atcaacaaag ttgagggtta gattcatttt ggaaccagct tcgtccagaa ggtcaatagc
    35161 cttatcagga agaaaacggt cttgaatata gcggttagat aaatgagcgg cagcttcaat
    35221 agcggctggg ctatatttga catgatgata gtcttcgtat ttcggttgga taccttttaa
    35281 aatcgtgatg gtttcctcaa cagaaggttc atcaacttta acgggttgca tacgtcgttc
    35341 taaggcagcg tctttttcaa taatacgata ttcatttaag gtggtagcgc cgaccaactg
    35401 caattcaccg cgggccaagg ctggttttaa aatattacca gcatccatat tgccgtctcc
    35461 tgcagaacca gcaccgacaa tctcatgaat ttcatcaata aagagaatca catccttgcg
    35521 attgcgaatt tcttccatta atttttgcat gcgctcttca aactgaccac ggatacctgt
    35581 tccctgaacg aggctaacca catcaagacg aatcacttgc ttgccttgga gtttttgagg
    35641 aacagtacca tcaataattt tttgagccaa accttctaca acagcagttt taccaactcc
    35701 aggctcacca attagcacag gattattttt agtacggcgg ttgaggatct cgataatgcg
    35761 tgtaatctct tcgtcacgac caataacagg atcaatatta ccatttcttg caatatctgt
    35821 gacattaatc ccaaactctt ctaacaagcc ctttgcttgc tgatttggtg tttgtggctg
    35881 agcaggtcgt tgtccgttgt agttaccacc atagcgtcct ccgccatttc cattttgccc
    35941 tgcctgagta ggtggggtat ttggaagatt accaaaagct ctaaaattat tcaaatcacc
    36001 aaaaaagtca tcaaagaaag gacttgtgga tctatcttgt gctctatatc ctggggttag
    36061 gccatttaaa atagaattgg caggatcgga tttcatgatt tgataacaat tttgacagag
    36121 atcaacctgt ctttgttttc cattaacact tgtataaaga tgaatagtag attcgtttaa
    36181 attacaattt tgacacagca taatatacct ccgagggttt atctaaaagt caaagtcatt
    36241 tagtcaaaaa tggtcaaact ttatattcat attatagcac cacggcttgg gaaatcaagt
    36301 aaaaagttta tcgctttagc gttagctttt agagagtaac atgacagagt aactttatta
    36361 agtttccaat gagcaaatgt ttaaaatcat tgaaaagagt aaa
//
LOCUS       DAUGSW010000015        32690 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUGSW010000015 DAUGSW010000000
VERSION     DAUGSW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32690
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.015"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            18..98
                     /locus_tag="VIB18_000879"
     tRNA            18..98
                     /locus_tag="VIB18_000879"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VIB18_000880"
     tRNA            105..175
                     /locus_tag="VIB18_000880"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VIB18_000881"
     tRNA            187..259
                     /locus_tag="VIB18_000881"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VIB18_000882"
     tRNA            268..339
                     /locus_tag="VIB18_000882"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VIB18_000883"
     tRNA            359..442
                     /locus_tag="VIB18_000883"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            701..886
                     /locus_tag="VIB18_000884"
     CDS             701..886
                     /locus_tag="VIB18_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765902.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWPEP"
     gene            1515..1823
                     /locus_tag="VIB18_000885"
     CDS             1515..1823
                     /locus_tag="VIB18_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ8765903.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSDVPYCLLSGCAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            1878..2090
                     /locus_tag="VIB18_000886"
     CDS             1878..2090
                     /locus_tag="VIB18_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ8765904.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            2200..2643
                     /locus_tag="VIB18_000887"
     CDS             2200..2643
                     /locus_tag="VIB18_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEQ8765905.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLSGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2647..3366
                     /locus_tag="VIB18_000888"
     CDS             2647..3366
                     /locus_tag="VIB18_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765906.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEAETDDEKGGHGHA"
     gene            3359..4174
                     /locus_tag="VIB18_000889"
     CDS             3359..4174
                     /locus_tag="VIB18_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8765907.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVIGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4214..4597)
                     /locus_tag="VIB18_000890"
     CDS             complement(4214..4597)
                     /locus_tag="VIB18_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8765908.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWEGITINQENWDLAPFLKHL"
     gene            complement(4648..5904)
                     /locus_tag="VIB18_000891"
     CDS             complement(4648..5904)
                     /locus_tag="VIB18_000891"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEQ8765909.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            5996..8308
                     /locus_tag="VIB18_000892"
     CDS             5996..8308
                     /locus_tag="VIB18_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8765910.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKNNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIVDYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8572..12138
                     /gene="rpoB"
                     /locus_tag="VIB18_000893"
     CDS             8572..12138
                     /gene="rpoB"
                     /locus_tag="VIB18_000893"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8765911.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12229..15870
                     /gene="rpoC"
                     /locus_tag="VIB18_000894"
     CDS             12229..15870
                     /gene="rpoC"
                     /locus_tag="VIB18_000894"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEQ8765912.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDRLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIADAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16022..16387
                     /locus_tag="VIB18_000895"
     CDS             16022..16387
                     /locus_tag="VIB18_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEQ8765913.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLSTFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16480..17418
                     /gene="tadA"
                     /locus_tag="VIB18_000896"
     CDS             16480..17418
                     /gene="tadA"
                     /locus_tag="VIB18_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEQ8765914.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYVRLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17402..18388
                     /locus_tag="VIB18_000897"
     CDS             17402..18388
                     /locus_tag="VIB18_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEQ8765915.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQDLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18390..18716
                     /locus_tag="VIB18_000898"
     CDS             18390..18716
                     /locus_tag="VIB18_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEQ8765916.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18691..19119
                     /locus_tag="VIB18_000899"
     CDS             18691..19119
                     /locus_tag="VIB18_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEQ8765917.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19124..19360
                     /locus_tag="VIB18_000900"
     CDS             19124..19360
                     /locus_tag="VIB18_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8765918.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEITLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19353..19787
                     /locus_tag="VIB18_000901"
     CDS             19353..19787
                     /locus_tag="VIB18_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEQ8765919.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19771..20097
                     /locus_tag="VIB18_000902"
     CDS             19771..20097
                     /locus_tag="VIB18_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8765920.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20195..21148
                     /locus_tag="VIB18_000903"
     CDS             20195..21148
                     /locus_tag="VIB18_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8765921.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSEEHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMQNFKKWKQDNVN"
     gene            21207..22403
                     /locus_tag="VIB18_000904"
     CDS             21207..22403
                     /locus_tag="VIB18_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEQ8765922.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHAEAVKILLNDLIHFGIIAAYDEITGVGHRIVAGGEYFKESVV
                     VDDTVVEQVEELSALAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQAPELKDAADVVNMLNKKSGLGG
                     VSGISSDMRDIEAGLQENNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22590..22898
                     /locus_tag="VIB18_000905"
     CDS             22590..22898
                     /locus_tag="VIB18_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765923.1"
                     /translation="MYVFIEPNDLKDYLITIYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLPLIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(22981..23751)
                     /locus_tag="VIB18_000906"
     CDS             complement(22981..23751)
                     /locus_tag="VIB18_000906"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEQ8765924.1"
                     /translation="MKIGIIGVGKMASTIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDLIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23799..24866)
                     /gene="pepA"
                     /locus_tag="VIB18_000907"
     CDS             complement(23799..24866)
                     /gene="pepA"
                     /locus_tag="VIB18_000907"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEQ8765925.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEDAGVNFQYYCGKGGTDAGAAHLQNDGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            25322..25615
                     /locus_tag="VIB18_000908"
     CDS             25322..25615
                     /locus_tag="VIB18_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEQ8765926.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25612..25929
                     /locus_tag="VIB18_000909"
     CDS             25612..25929
                     /locus_tag="VIB18_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEQ8765927.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25947..26591
                     /locus_tag="VIB18_000910"
     CDS             25947..26591
                     /locus_tag="VIB18_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEQ8765928.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMLAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKGQKNQLK"
     gene            26724..27119
                     /locus_tag="VIB18_000911"
     CDS             26724..27119
                     /locus_tag="VIB18_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8765929.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLISIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27379..28020)
                     /locus_tag="VIB18_000912"
     CDS             complement(27379..28020)
                     /locus_tag="VIB18_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEQ8765930.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRNFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28040..29017)
                     /gene="dusB"
                     /locus_tag="VIB18_000913"
     CDS             complement(28040..29017)
                     /gene="dusB"
                     /locus_tag="VIB18_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEQ8765931.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELTDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(29004..29876)
                     /gene="hslO"
                     /locus_tag="VIB18_000914"
     CDS             complement(29004..29876)
                     /gene="hslO"
                     /locus_tag="VIB18_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEQ8765932.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIINDKA"
     gene            complement(30023..31516)
                     /gene="rofA"
                     /locus_tag="VIB18_000915"
     CDS             complement(30023..31516)
                     /gene="rofA"
                     /locus_tag="VIB18_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEQ8765933.1"
                     /translation="MIEKYLESSIESKCQLVVLFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVQHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
     gene            31748..>32690
                     /locus_tag="VIB18_000916"
     CDS             31748..>32690
                     /locus_tag="VIB18_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEQ8765934.1"
                     /translation="MVSSYMFVRGEKMNNKMFLNKEAGFLAHTKRKRRFAVTLVGVFF
                     MLLACAGAIGFGQVAYAADEKTVPSHSSPSPDFPWYGYDAYSGWIPRYHDLKVNLKGS
                     KEYQVYCFNLKRSFPRRTHSITNNFYKKIVGSGSVFKSYAENPRVLDENLDKLEKNIL
                     NVIYNGYKSNANGFMNGIEDFNAILVTQTAIWYYSDSSPASATAVEKMWDREVKDGDI
                     SLEQVKLMREALKKLIDPNLEATAVNKIPSGYRLNIFKSENEDYQNLLSAEYVPDDPP
                     KPGDTSEHNPKTPELDGSPIPEDPKHPDDNLEPTLPPV"
BASE COUNT         9829 a         5886 c         7062 g         9913 t
ORIGIN      
        1 aaaatttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tgtaaacctt gttttttgtt
      481 ttgatcttaa ctgtagctac gtagtacaat ctcttatatt actgataagg tctatttaat
      541 gcgcaagatt tgtggtatga tgaatatgat tgagtattga tgctttatgg gattaccggt
      601 aaggttttga aaaaagtttg tcactactag gtgctttttt agctatagaa agacagttat
      661 ggattgatgt attgtaacta atgttggagg ttaatggtgg ttgagttttg agatatttac
      721 actgataatc gggtggaaac tggttgggta tcgggtaatg gagtgtggtt cttcgtttaa
      781 gcaaggagat tatcgtttgg tggttcatat ttgcttgtta aatgttaggg atgagatgct
      841 gagtcagcaa ggccatgaag ataaagctga ctggccagag ccttgagatg tgacgtttgg
      901 tggaagtcct ttttggtgag atggcacagc atatagtaat attagatcct gaggaagaat
      961 tgggactttc attaggctta tgacctcact ttacaattca tttcgatgat gggtttgatg
     1021 atatgttttt agttcaggac tttgtagagt tggagaattt ggttctttat gaggaagaag
     1081 tgcaggtaat tcgttgagcc agtcgtgaag atattttagg tatgattgat gaaggttcgt
     1141 tcattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggc caatataaag
     1201 tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt atatttgata
     1261 gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga gcttctgtaa
     1321 aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac gatttatcga
     1381 tggtcatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata gatgacaata
     1441 agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat gatgtttata
     1501 agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc gtttacttgg
     1561 aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct gttactatca
     1621 gagcattaaa tcagttatgg ctccttactc ttagccgaaa agatatgatg gatattggta
     1681 taccgattgg tagtgatgtg ccttattgct tgctttcagg ttgtgcccaa gtcactggta
     1741 aaggtgaagt ggtttgtcgc attttggggc tgttatcgtc ttgggtggtt ttggttaaac
     1801 cagattttgg tatctcgact tgaacatttt ttctagatat taattgtaaa atcatttcaa
     1861 gagtgtctac tactcatttg gttgcggcga ttgaagcggg taactataat gatgggatat
     1921 tgactgaaat gaacaatttg ctggaagata ttttcattgc caagcgaccc tttattcaaa
     1981 aaataaaaga gaaaacactg caagctggtg ctgctactac tttgatgaca ggaagtggac
     2041 cgactgtttt tgctttgtgc cagaccgaaa aacaaactat aatagtttaa aaggactttg
     2101 caaggaagtt tttaaggtga gaatgttgta atattttgtt gggattgctt ctttggaagc
     2161 ttcatgttat aattaactgg ttaatgaaag aggagattta tggggacttt agaaaaaaaa
     2221 cttgataact tagtaaatac tattttatta aaagcagaaa atcagcatga gttattattt
     2281 ggagcttgtc aaagtgacgt taagcttact aatacgcaag aacatatttt aatgttacta
     2341 tctcagcaac gtctcactaa tacagatttg gctaaggcat taaatattag tcaggcggca
     2401 gtaactaagg ctatcaagag tttggtcaaa caagacatgc tatcaggaac taaggatacg
     2461 gttgatgcta gggtgactta ttttgaatta accgagttag ctaagcctat tgcgtcagaa
     2521 catacccatc atcatgatga aaccttaaat gtttacaacc gtttattaca aaaattctcc
     2581 gcgaaagaat tagagattgt agataagttt gtaacagttt ttgctgagga attagaaggg
     2641 taatccatga gatacatatc agtgaaaaat ctctcctttc aatatgaaag tgagccagtt
     2701 ttagaaggga tcacttatca tttagatagt ggagaatttg tcaccatgac cggtgaaaat
     2761 ggcgctgcaa agtcaacctt aataaaagca accttaggaa ttttacaacc aaaggctgga
     2821 cgagttacta ttgctaaaaa aaataaagac ggtaaacaat taaggattgc ttacttgccg
     2881 cagcaagtag ctagctttaa cgctggtttt ccatccaccg tttacgagtt tgtcaaatca
     2941 ggtcgctacc cacgtagtgg ttggtttaga catttgaaca aacacgatga agagcatgta
     3001 caagcaagct tagaagcagt cggcatgtgg gaaaaccgtc ataagagaat tggtagttta
     3061 tcaggtggtc aaaaacaacg tgtggttatt gcccgtatgt ttgcttctga ccctgatatt
     3121 tttgtgctag acgagccaac aacgggaatg gatagcggta ctactgatac cttttatgaa
     3181 ctgatgcacc acagtgcaca tcaacatggg aaatccgttc tgatgattac ccatgaccca
     3241 gaagaagtga aggcttatgc tgatcggaac attcatttag tcagaaacca aaaacttcct
     3301 tggcgttgtt tcaacattca tgaagctgaa acagatgacg aaaaaggagg tcatggtcat
     3361 gcttgatatt ttatcctatg atttcatgca acgggcggta atggcggtag ttgccattag
     3421 tatttttgct ccgattttag gtattttcct tattttacgt cgtcaaagtt tgatgagcga
     3481 tacccttagt catgtttctt tggctggggt agcgcttggg gtagtcattg gtatttcacc
     3541 aaccatcact actattattg ttgtggtttt agctgctatt ttgttagaat acctgcgtgt
     3601 agtttacaaa cactacatgg agatttcaac ggcgattttg atgtcacttg gcttggccct
     3661 atctctgatt attatgagta agtcgcatag ttcatcaagc atgagtttag aacaatacct
     3721 ttttggatcg atcatcacga ttagtatgga acaagttgtc gccttgtttg ctattgctgc
     3781 gattatttta atcttgaccg ttctcttcat tagaccgatg tacattttga cctttgatga
     3841 agatactgct tttgtagatg gtttgcccgt tcgcttgatg tctgttctat tcaatatcgt
     3901 cactggggtt gctattgctt tgaccattcc agcagcagga gcacttttgg tttctaccat
     3961 tatggtcttg ccagcaagta tcgcaatgag attgggtaaa aactttaaaa cagttatctt
     4021 actgggaatt gtcatcggtt ttagcggtat gttatctggt attttcttat cttatttctt
     4081 tgaaacgcca gctagtgcca ctattaccat gattttcatt agtattttcc tcttagttag
     4141 tctaggtgga atgcttaaaa aacggttatt ttaataagaa aaatcctcac atgtttaaca
     4201 tgtgaggatt tatttataaa tgctttaaaa agggggcaag gtcccaattt tcttgattaa
     4261 tggtgatgcc ctcccaaaag ctatcattag ttaaacgagg aatcaaatga aggtgaaaat
     4321 gagtcccctc atccatcaac tccttgtcat tgctgacgct agtgacgcct gaaatgggaa
     4381 ggtgctgctc tagcttagca actagagcgg cttgtaagtc gatgagatca tagcgcactt
     4441 cctttggtag ttgtgtcaga ctagtgtaat ggtctttgga aatcagtaaa aggtgcccct
     4501 tttggatagg atcaatatca aaaacaacct tgaaatattg actttgagtc agtagctgat
     4561 ttgctttgag ctgatggcaa aagatacatt ctgtcatagg tacatctcct tatgaaaaaa
     4621 cgagccagag ctcgtttaat cggttatcta gtaagtgaga acagcgtatt ttttcttacc
     4681 gcggcgaata acggttaatt gatcatcaat tttatcatca ttacttaatt ggtaatctaa
     4741 atcttgaacg cggtctccgt taatgtagat tgctccattt tgcacgtctt cacgcgcttg
     4801 gcgttttgat ggggaaatac ctgcggtgac aagcatgtca acaaggttaa ggctgtcttc
     4861 tgattgaacg tgataatttg gtacattgct caatccttgt tttaattcat tagcagaaag
     4921 atttttgatg tttccagcaa ataactgctc ggtaatgtta agagcttgtt tataagcttc
     4981 ttcgccatga accaaggtaa ccacttcgcg tgccaaggtt ttttgagcga gacgctcgtg
     5041 acgagcggca ttaaattgag tttcaatttc tgcaatctca tctagagata agaaggtgaa
     5101 gattttcaag aaacgcactg catcatcatc catgacattt aaccagaatt ggtacatctc
     5161 gtaaggagac gtcttatcgg catcaagcca gacagcatta ccttctgatt taccgaattt
     5221 tttcccggtt gagtcagtga tgagtggtac agtcatgacg tgcccagttt tatcagcctt
     5281 tttgcggagc aattcagtac cagctgtcat attaccccac tggtcagagc cgccaatttg
     5341 taaggttaca ttatgcttgt cattgagttc gtagaagtcg tagccctgca tgatttggta
     5401 agcaaactca gtgtaagaaa tgcctgtttc aatgcgtttt ttaacagagt ctttactcat
     5461 catgtagtta acggtgaagt atttaccgac atcacggagg aagtcaataa agctgatttg
     5521 cgagaaccag tcgtagttgt tgacaagctc tgctttatta tcaccatttt caaaatcaag
     5581 gaaagtagac aactgccctt taatcttgtc actccactcc aaaactgttt ctttggtttg
     5641 aaggctgcgc tctgcatctt taaaggaagg atcaccaatt aaacctgtgg caccacccac
     5701 aagagcgtaa ggtttgtgcc ctgctagttg caagcgacga gatgttaaga tagccactag
     5761 atggcccaga tgaaggctgt cagcggttgg atcataaccg gtataatagg atacttgccc
     5821 ttctgttaat gctttgacaa gggcttgttc atcagtcgtt tgaaagacca agccacgagc
     5881 tttgagttct tcaaaaatat tcataggctt tctccatttt cattatagtt tcgaatcatt
     5941 atatcaaaaa acgctactgc tatgcaagct ttatcaaagt ttggtataat gataaatgag
     6001 gtattttatg gtgaaatgga acacgaaaca aaagcgtata agtcatcaaa gattaggtct
     6061 cttggatttg gggccggtgc tattacgtac gttgagacta ctgtctaact ttttttatat
     6121 tgttatcttc ctttttggaa tgatgggatt tggtatggca tttgggtatt tggctagtca
     6181 gattgaatct gttaaggtac caagtaaaga aagtttagtc aaacaagttg aatcattaac
     6241 gatgatttcg caaatgaact attctgataa tagtttaatt tctactttag atacggattt
     6301 acttcgaaca ccagtagcta atgatgcgat ttcagagaat atcaaaaaag ctattgtatc
     6361 aacagaagac gaacattttc aagaacataa aggtgtcgtg ccaaaagctg tttttcgggc
     6421 aacattggct tctgtattgg gatttggaga agctagtgga ggttcgacct taacacagca
     6481 attggtcaag caacaagttt tgggagacga tcccacattt aagcgcaagt ctaaggagat
     6541 cgtttacgct cttgccttag agcgttatat gtccaaaaac aatatcttat gtgattatct
     6601 taatgtttca ccttttggtc gtaacaacaa gggccaaaat attgctggtg ttgaagaagc
     6661 tgcgcgtggc atttttggcg tttctgccaa agatttaacg gtgccacagg cagcattttt
     6721 ggcgggtctt ccgcagagtc ctattgttta ctctccttat ttgtcaacgg gacaactgaa
     6781 atcagaaaag gacatggctt atggcatcaa gcgtcagcaa aatgttctct ataacatgta
     6841 ccgtacaggt gttctgtcta aaaaagaata cgaggactat aaggcttatc cgattcaaaa
     6901 ggattttatt caaccgggaa gtgcaatagt aaataatcac gattaccttt attacacggt
     6961 gttagcggat gctaaaaaag ccatgtatag ctatttgatt aagcgagata aggtgtctag
     7021 tcgtgatttg aaaaatgacg agactaaagc tgcttatgaa gagagagcct taacagaatt
     7081 gcaacagggt ggctatacca tcaccacaac cattaataag cctatttaca atgcgatgca
     7141 gacagcggca gctcagtttg gtggcctgtt agatgatggc actggtacag ttcaaatggg
     7201 aaatgtcttg acagacaatg cgactggtgc tgtgttaggt tttgttggtg gtagagatta
     7261 tgctctgaat caaaataatc atgctttcaa tacagttaga tcgccaggtt ctagcattaa
     7321 accgataatc gcttatggtc ctgctattga tcaaggttta atggggagtg ctagcgtttt
     7381 gtctaattac ccaacaactt actcgagtgg ccaaaaaatc atgcatgctg atagtgaagg
     7441 aacagccatg atgccacttc aagaggccct aaatacttct tggaacatcc cagctttttg
     7501 gacacagaaa ttactgcgtg aaaaaggggt cgatgtcgaa aattatatga caaaaatggg
     7561 ttataagatt gtagactact cgattgaaag tttacctcta gggggcggta ttgaagtctc
     7621 ggttgctcaa caaaccaatg cttaccaaat gctttcaaac aatggcttat atcaaaagca
     7681 atatattgta gataagatta ctgctagcga tggtacagtc gtttacaaac atgaaaataa
     7741 gccaattcgt attttttctg cagcaacagc aacgatttta caagaattgt tgagaggtcc
     7801 gattacttca ggcgctacga ctactttcaa gaaccgtttg gcggctatta atccgtggct
     7861 tgctaatgct gattggattg gtaagaccgg aacaactgag aattatacgg atgtttggct
     7921 agtcctgtct actccaaaag ttaccttagg cggttgggca ggacatgatg ataatacctc
     7981 attagcgcca ttaacaggat ataacaataa ttctaattac cttgcctatt tagctaatgc
     8041 cattaatcag gccgatccca atgttattgg agtagggcaa cgcttcaact tagatccagg
     8101 agtcattaag gcgaatgtct tgaagtcaac aggtttacaa ccaggaactg ttaatgtcaa
     8161 tggacatact ttttctgttg gtggagaaat gaccaccagt ctatggtccc aaaaaggacc
     8221 gggggctatg acttaccgat ttgctattgg tggcacggat gccgattatc aaaaagcctg
     8281 ggggaacttc gggttcagaa aaaattaggt tgccatttat cgataaaaag ggtataatag
     8341 taataactat ttgtcgtcca atctagctga aatattgtcc agttaggaag aacagcagtt
     8401 aaatcacact gataaagtca gatttagctg ctctttttgt gtctattttt agaaaagata
     8461 gggtttgtaa cctatattta aatattctaa aaattaacat ttagggcaaa tgataactta
     8521 gttgcgattt gctgaaacag caaagcttaa atagaagaag gagctaaaaa cttggcagga
     8581 catgaagttc gatacggaaa acaccgtaca cgtcgtagct tttcaagaat caaagaagtt
     8641 cttgatttac caaatttgat tgaaattcaa actgactcat tccaagattt cctcgattca
     8701 ggtttgaaag aagtatttga agatgtactt cctatttcaa actttacgga tactatggaa
     8761 cttgaatttg ttggttacga atttaaagaa cctaaatata cccttgaaga agctcgtatc
     8821 cacgatgcaa gttattctgc accaatcttt gttaccttcc gtttggtcaa taaagaaact
     8881 ggtgagatta aaactcaaga agtcttcttt ggtgatttcc caatcatgac ggaaatgggt
     8941 acctttatta tcaatggtgg tgaacgtatc atcgtttctc agttggtgcg ttctccaggt
     9001 gtttatttca acgataaagt tgataaaaac ggtaaagttg gttacggatc aacagtgatt
     9061 cctaaccgtg gggcttggtt ggaattagag actgactcaa aagacattgc ctacactcgt
     9121 attgaccgta cccgtaagat tccattcaca accttggttc gtgcccttgg tttctcaggt
     9181 gatgatgaaa ttgttgatat ctttggtgaa agcgaccttg ttcgtaatac cattgaaaaa
     9241 gacattcaca aaaatccaag tgattctcgt acagacgaag cccttaaaga aatttacgag
     9301 cgtcttcgtc caggtgagcc aaaaactgca gatagctctc gtagtctttt gattgcgcgt
     9361 ttctttgatg cacgtcgtta cgatttggct gcggttggtc gttacaaagt gaacaaaaaa
     9421 cttaatatca agactcgtct tttgaaccaa atcattgctg aaaaccttgt ggatgctgaa
     9481 actggcgaaa ttttggtaga agctggaact gagatgactc gtagcgtcat cgaatccatc
     9541 gaagaacacc ttgacggtga tttgaacaag tttgtttaca caccaaatga ttacgctgtt
     9601 gttactgaac cagttgttct tcaaaaattc aaggttgtgt caccaattga tcctgaccgc
     9661 gtggtaacta ttgttggtaa tgccaatcca gatgacaagg tacgtgcttt gacacctgct
     9721 gatattttgg cagaaatgtc ttacttcttg aaccttgctg aaggccttgg aaaagttgac
     9781 gatattgacc acttgggtaa ccgtcgtatc cgtgccgttg gtgaattgct tgccaaccaa
     9841 ttccgcatcg gtcttgctcg tatggagcgt aacgttcgtg agcgtatgtc tgttcaagac
     9901 aacgatgtgt taacaccaca acaaatcatc aatatccgtc ctgtcacagc agctgtcaaa
     9961 gaattcttcg gttcgtctca gttgtcacag ttcatggacc aacacaaccc attgtcagag
    10021 ttgtctcaca aacgtcgttt atctgcctta ggacctggtg gtttgacacg tgaccgtgct
    10081 ggttatgagg ttcgtgacgt gcattacacg cactatggcc gtatgtgtcc gattgaaaca
    10141 cctgaaggac caaacattgg tttgattaac aacttgtctt catttggaca tcttaataaa
    10201 tatggtttca tccaaacacc ttaccgtaag gttgaccgtg cgactggtag ggtaactaac
    10261 gagattgttt ggttgactgc cgacgaagaa gacgaataca cagttgcaca ggccaattcg
    10321 aaactaaacg aagatggcac ttttgctgaa gaaatcgtta tgggtcgtca ccaaggtaat
    10381 aaccaagaat tttctgcaag tgttgttgat ttcgttgacg tttcccctaa acaggtagtt
    10441 gctgttgcga cggcatgtat tcctttcttg gaaaacgatg actccaaccg tgccctcatg
    10501 ggtgccaaca tgcaacgtca ggctgtgcca ttgattgatc caaaagcacc atatgttggt
    10561 actggtatgg aatatcaagc tgcccatgac tcaggcgctg cggtgattgc tcagcacaat
    10621 ggtaaagttg tcttttctga tgctgaaaaa gtggaaatcc gtcgtcaaga tggctcactt
    10681 gatgtttacc acattaccaa attccgtcgt tcaaactcag gaacagccta taaccaacgc
    10741 acccttgtta aagtaggaga cattgttgaa aaaggtgatt tcatcgctga tggaccttct
    10801 atggaaaatg gtgaaatggc tcttggacaa aacccagtcg ttgcttacat gacttgggaa
    10861 ggttataact ttgaggatgc cgttatcatg agtgagcgcc ttgtgaaaga agatgtctac
    10921 acatctgttc acttggaaga attcgaatct gaaacgcgtg atacaaaact tggccctgaa
    10981 gaaatcactc gggaaatccc aaatgttggt gaagaagccc tcaaagacct tgacgaaatg
    11041 ggcattatcc gtatcggtgc tgaggttaaa gaaggcgaca tcttagtagg taaagtcaca
    11101 cctaaaggtg aaaaagacct ttctgctgaa gaacgtttac ttcacgccat ctttggggat
    11161 aaatcgcgtg aagtgcgtga tacctcactt cgtgtccctc atggtggtga tggtattgtt
    11221 cgtgatgtga aaatctttac acgcgctaac ggcgatgaat tgcaatcagg tgttaatatg
    11281 cttgtgcgtg tttacatcgc tcaaaaacgt aaaatcaagg tcggagataa aatggccggt
    11341 cgtcacggaa acaagggtgt cgtttcacgt attgtaccag ttgaagacat gccatacctt
    11401 ccagacggaa caccagttga catcatgttg aaccctctcg gggtgccatc acggatgaat
    11461 attggtcagg ttatggaact tcaccttggt atggctgctc gtaatcttgg cattcacatt
    11521 gcaacacctg tctttgacgg ggcttcatca gaagaccttt gggacactgt tcgtgaagct
    11581 ggcatggata gcgatgctaa gacggtcctt tatgatggtc gcaccggtga accatttgac
    11641 aaccgtgtat ccgttggtgt catgtatatg atcaaacttc accacatggt tgatgataaa
    11701 cttcatgccc gttctgtagg accatactca cttgttaccc aacagccact tggtggtaaa
    11761 gctcaatttg gtggacaacg ttttggtgag atggaggttt gggcccttga agcttatggt
    11821 gcatcaaatg ttcttcaaga aatcttgacc tacaagtcag atgacgtcac aggacgtttg
    11881 aaagcctatg aagcgattac taaaggtaaa ccaattccaa aaccaggtgt accagaatcc
    11941 ttccgtgttc ttgtaaaaga attgcaatcg cttggtcttg atatgcgtgt gcttgacgag
    12001 gatgataatg aagtggaact tcgtgatctt gatgaaggtg aagacgatga tattatgcat
    12061 gttgacgatc tcgagaaggc acgtgaaaaa caagctcaag aaacccaaga agtttctgaa
    12121 acaactgacg aaaaataagc aatcaattct tattaaataa ttatttactg gtctggggca
    12181 aaggccccag gaactggtaa agtcatcaaa ggcagaaagg taaaactagt ggttgacgta
    12241 aatcgtttta aaagtatgca aatcacatta gcctcaccaa gtaaggtccg ttcatggtct
    12301 tatggtgaag ttaaaaaacc tgaaacaatc aactaccgta cattaaaacc agaacgtgaa
    12361 ggactctttg acgaagtcat ctttggtcca acaaaagact gggaatgtgc gtgtggtaag
    12421 tacaaacgta tccgttataa agggatcgtt tgtgaccgct gtggggttga ggtaactcgt
    12481 gctaaagtac gtcgtgaacg tatgggtcac attgagttaa aagctcctgt atcacatatc
    12541 tggtatttca aagggattcc atctcgtatg ggattgactc ttgatatgag tcctcgtgcc
    12601 cttgaagaag tgatctattt tgcggcttat gtggtcattg atccaaaaga tacaccgctt
    12661 gaaccaaaat cattattaac agaacgtgaa taccgtgaaa aactacaaga gtatggtcat
    12721 gggtcatttg tcgctaagat gggtgctgaa gccattcaag atctcttgaa acgtgtggac
    12781 ttggcagctg aaatcgctga attaaaagaa gagttgaaat ctgcttctgg tcaaaaacgg
    12841 attaaagcag ttcgtcgttt agacgtcctt gatgccttta acaaatctgg aaataaacca
    12901 gaatggatgg ttcttaacat cctgccggtt attccaccag atcttcgtcc gatggttcaa
    12961 ttggatggtg gtcgttttgc ggcatcagac ttgaatgact tgtaccgtcg tgtgattaac
    13021 cgtaataacc gtttggcacg tttgttagaa cttaatgccc ctggcatcat tgttcaaaat
    13081 gaaaaacgaa tgcttcaaga agccgttgat gctttgattg ataatggtcg tcgtggtcgt
    13141 ccaatcactg gaccaggaag tcgtccattg aaatcattga gccacatgct taaaggtaaa
    13201 caagggcgtt tccgtcaaaa cttgcttggt aaacgtgtag acttctctgg acgttccgtt
    13261 atcgctgttg gtccaaccct taaaatgtat caatgtggtg tcccacgtga aatggctatc
    13321 gagcttttta aaccatttgt aatgcgcgaa attgttgcca aagaatatgc tggtaacgtt
    13381 aaagccgcta aacgtatggt tgaacgtggc gacgaacgca tctgggatat cttagaagaa
    13441 gttatcaaag aacacccagt cctacttaac cgcgcaccga cccttcacag acttggtatt
    13501 caggcttttg aaccggttct tattgacggt aaggcacttc gtcttcaccc acttgtgtgt
    13561 gaggcctaca atgccgactt cgatggagac caaatggcta tccacgtgcc actttcagaa
    13621 gaagcacaag ctgaagctcg tcttttgatg cttgctgcag agcacatctt gaaccctaaa
    13681 gatggtaaac cagttgttac cccatctcag gatatggttc ttggtaacta ctatcttacg
    13741 atggaagatg ctggtcgcga aggcgaaggt atgattttca aggataaaga cgaagctgtg
    13801 atggcatatc gtaatggtta tgctcatctt catagtcgtg tgggtatcgc tgttgacagc
    13861 atgccaaaca aaccttggaa agacaatcaa agacataaaa tcatggtgac aactgttggt
    13921 aagattctct ttaacgatat catgccagag gaccttcctt acctccaaga gccaaacaat
    13981 gccaacttga cagaaggaac acctgataaa tacttccttg aacctggtca agacatccaa
    14041 gaagtgattg atcgcttaga catcaatgtg ccatttaaga agaaaaacct cggtaacatc
    14101 attgcggaaa ccttcaaacg tttccgtaca acagaaacat cagccttcct tgaccgcttg
    14161 aaagaccttg gttactacca ttcaaccctt gctggtttga cagtgggtat cgctgacatt
    14221 cctgttattg ataataaagc tgaaatcatt gatgctgctc accatcgtgt tgaagaaatt
    14281 aacaaagcct tccgtcgtgg tttgatgaca gatgatgacc gttatgttgc cgttacaaca
    14341 acatggcgtg aagctaaaga agcccttgaa aaacgtctga ttgaaacaca agatcctaag
    14401 aacccaatcg ttatgatgat ggactcagga gctcgtggta acatctcaaa cttctcacag
    14461 cttgctggta tgcgtggttt gatggctgct cctaacggac gcatcatgga acttcctatc
    14521 ttgtcaaact tccgtgaagg tttgagcgtt ttggaaatgt tcttctcaac ccacggtgca
    14581 cgtaaaggga tgaccgatac ggcccttaaa acagccgact caggttatct tactcgtcgt
    14641 ttggttgacg ttgcccaaga tgttatcatt cgtgaggacg attgtggcac tgatcgtggt
    14701 cttcttatcc gtgctattac agatggtaaa gaagttaccg aaacgcttga agagcgtctt
    14761 caaggtcgtt acacacgtaa atcagtcaaa caccctgaaa ctggtgaagt cttgattggt
    14821 gctgaccaat taatcactga agacatggct cgtaagattg ctgatgcagg tgttgaagaa
    14881 gtgaccattc gttctgtctt tacctgtgcg actcgtcatg gtgtctgccg tcactgttat
    14941 ggtatcaact tggcaactgg tgatgctgtt gaagtgggtg aagcagttgg tactattgct
    15001 gcccaatcta tcggtgagcc tggtactcag cttaccatgc gtaccttcca cacgggtggt
    15061 gtagcctcaa ataccgatat cacccagggt cttcctcgta ttcaagagat ctttgaagca
    15121 cgtaatccta aaggggaagc ggtcattact gaagtgaaag ggaatgtcgt cgagattgaa
    15181 gaagatgcgt caactcgtac caagaaagtc tacgttcaag gaaaaactgg catgggcgaa
    15241 tatgtcgtac catttacagc acgtatgaaa gttgaagttg gcgacgaagt taatcgcgga
    15301 gctgccctta cagaagggtc aattcaaccg aaacgtctcc ttgaagtgcg tgataccttg
    15361 tcagttgaaa cgtaccttct tgcagaagta caaaaagttt accgtagcca aggggtagaa
    15421 atcggagaca aacacgttga ggtaatggtt cgccaaatgc ttcgtaaagt tcgtgtcatg
    15481 gatccaggtg atacagacct ccttccaggt acacttatgg atatttctga tttcacagat
    15541 gctaacaaag atattgttat ctctggtggt attcctgcga cctctcgtcc tgttcttatg
    15601 ggtattacta aggcttccct tgaaaccaat tccttcttat cagctgcatc cttccaagaa
    15661 acaactcgtg ttcttacaga tgctgctatc cgtggtaaga aagaccactt acttggtctt
    15721 aaagaaaatg ttatcattgg taaaatcatt ccagctggta ctggtatggc gcgctaccgt
    15781 aacattgaac cacaagcgat gaatgagatt gaagtgattg atcatacaga agtctcagca
    15841 gaagccgttt ttacagcaga agcagaataa tctcatgaaa gagtccttag gggctctttt
    15901 ttgtctgagt ttgttggcag taaaaagcat tgacaatcag tcttagtccc aatgagcaga
    15961 tgtttttcaa aatacttatg atttagctat aataatgcat aagaggaata ggtaatgtgt
    16021 tatgtatcaa gtaattaaaa tgtatggtga ttgggagcct tggtggttca tcgatggatg
    16081 gcaagacgat attatagatg agcaacaatt tagtgactgg caagaagcgc ttgattattt
    16141 taatcaagaa tggcagcgca tgaaagctat ttttcctagt tatcatagtc aaaagaattt
    16201 gttatctact ttttgggaaa aagaagataa aagatggtgc gaggactgtg acgaagattt
    16261 acagcagttt cattctcttt tactccttaa aaataaagat attgtaccaa gcaataatta
    16321 tatccctgaa tttgaacaac gaaatgattc accacaggta gcttatcttt gcaagttaaa
    16381 cctttaagtg tttgttaaaa acaaaataag ttaaaagaaa atatcacttc ttctgatatt
    16441 ttcttttttt gtttacgaat aaatgagtaa ggaggaatta tggtacaagc attagcaaaa
    16501 gctattctag caaaagctga acaggttcag gcacaagata tttatatttt gccaagagca
    16561 gatcaatatg atcttttttt acgaatagga gatgaaagga gattagttga tgtttatcag
    16621 agcgatcgga tggctcctct tattagtcac tttaaattcg ttgcaggaat gatagttggt
    16681 gaaaagagac gttgtcaggt gggttcatgt gattataagc ttagtaaaga taagcagtta
    16741 tctttgcgct tatctagcgt gggtgattat cgcgggcaag aaagcttagt gattcgtctg
    16801 cttcatcatc aaaataaaag tgtacattat tggtttgatg gattgacaaa agtagccaat
    16861 caagttggcg gtagagggtt gtatttattt gcaggaccag ttgggtctgg gaagacaacc
    16921 ttgatgtacc agctgatttc gaattatcat caaaaagcac aggttattag tatagaagat
    16981 cctgtagaaa ttaaaaatca ccagatttta caattacaag tgaatgatga tattggtatg
    17041 acttatgaca atttgatcaa actgtcttta cgccatcgac cagatatttt agttattggt
    17101 gagattcgag atagtcaaac agcaagagcc gttattaggg ctagtctaac aggtgccatg
    17161 gttttttcaa cggttcacgc taaaagtatc tcgggtgttt atgtaagatt gttagaactt
    17221 ggtgtaacga aagcagaact gtctaattgc ttagcattaa ttgcttacca aaggttactt
    17281 aatggaggag cattgattga ctctactcaa aacgaatttg aatattattc ctcatcgaac
    17341 tggaatcaac aaattgatca gcttcttgag gcaggacatc tcaatcccaa gcaagctaag
    17401 cttgaaaaaa ttatctagta aacatcagca taaattcatt caattactag ctaatctttt
    17461 atctacagga tttagcttcg cagaggttat tgctttttta aaaagaagcc agttgcttca
    17521 gctagattat gttcttaaaa tggaagagtc tttattaaaa ggacaagact tagcagatat
    17581 gttgtcgggt ttaggttttt cagatgctat tcttactcaa attagtttag ctgatagaca
    17641 cggtaatatt gaaacaacat tagtagcgat tcaacattac ttgaaccaaa tggcaaggat
    17701 cagacgaaaa actgttgaag ttatcaccta tcctcttatt cttttacttt ttctttttgt
    17761 gatgatgcta gggttgagac gctatttagt ccctcaatta gaaactcaaa atcagataac
    17821 ttactttctt aaccattttc ctgccttctt tataggtttt tgctcaggtc ttattttgtt
    17881 gttcgggatg gtatggctac gatggcgatc tcaaagccgc ttgaaactct atagtcggct
    17941 aagccgttat ccttttttag gtaaactgtt aaaacaatac ttaactagtt attatgctag
    18001 agaatggggt acgttaatag gtcaaggtct tgatttgatg actattttag acattatggc
    18061 cattgagaaa tcctcactaa tgaaagaatt agctgaggac atcagaatga gtctgcttga
    18121 agggcaagcc tttcacatta aagtagctac ctaccctttt tttaaaaaag aattaagttt
    18181 aatgattgaa tacggtgaaa tcaaatcgaa actgggggct gagttggaaa tctatgccca
    18241 ggaaagctgg gaacaatttt ttagtcagct ttatcaagtg acacaactta ttcaaccagc
    18301 tattttttta gtagttgctg tgacaatcgt catgatttat gcggcaatcc tattaccaat
    18361 ttaccaaaat atgggaggta ttttttaaga tgattaatca atggaacaac ttacgacaca
    18421 agaagctaaa aggatttact cttctagaaa tgttattggt gattcttgtc atcagtgttt
    18481 tgatgctatt atttgtgcct aatttaagca agcaaaaaga cagggttaca gaaacaggta
    18541 atgccgctgt tgttaaatta gtggagaatc aagcagaact atatgaatta tctcaaggct
    18601 caaaaccaag tttgagccag ttaaaggcag atggtagtat cactgagaaa caagaaaaag
    18661 cttatcaaga ctattatgac aaacataaaa atgaaaaagc ccgtcttagc aattaaagct
    18721 tttactttac ttgaaacttt actaagtttg tcagtgatga gtttcattat attgggattg
    18781 tctgtaccag tgacaaaaag ctatcaaaaa gtagaagagc atctattttt tagccatttt
    18841 gaacatttgt atcgacatca gcaaaagtta gccatattac agcaaaaaca gcgcgtcttg
    18901 gatatttctt caacaaaaat tgttacagaa ggtaatagcc taacagttcc taaatcaata
    18961 acagtgaatc atccttatcg gttagttatt gatcagatgg gaggcaacca ttccttagct
    19021 aaaattattt ttgacatgac tgatcgacgc tttaaatacc aattttatct agggagtggg
    19081 aattatcaaa aaacaagtca aagcttacat agcccttgaa agtatgatcg caacaggcat
    19141 cctctttagt attgtcattc tcgtcttaag tagtttacag cagagtcagg ctgctctaac
    19201 gtactatcga aagcagcaag aaaagcttaa tctagccttg atggcagtac aaactagaac
    19261 taaagagata acattgaatg gttgtcatat tactatttta cgtacggata gatacattag
    19321 tattcacgat gacgaaggag aagtgatgaa gattgagtaa acaattaagt aacataaaag
    19381 cttttaccct tctagaggcg ttaatagcct tactcgtgat atcagggtct ttattggttt
    19441 atcaaggttt gacccaaacc ctccttaaac gtagccatta tctagcccgt catgatcaag
    19501 acaattggct cttattttct catcaattgc gagaggagtt aagtggagca agattttaca
    19561 aagtagctga taataaacta tacgttgaaa aaggaaagaa agtactagct tttggccaat
    19621 ttaaaagtca tgattttcga aaatcagcta gtaatggaaa agggtatcaa cccatgttat
    19681 ttggaatatc acgtagtcat attcacatag agcagtcaca gatttgcatt actttaaagt
    19741 ggaaaagtgg gttagaaagg actttttatt atgcctttca agactaatct caaagcaggc
    19801 atccttttgt atgctatgtt tatggctagt atttttttgc tggttttaca ggtttacctt
    19861 tctcaagtga cagctctaca caaggaatac caagctcaaa ctgactatgt taaagcccga
    19921 ctgatagcag aaatagttta tcaagatcat agatataaag cttctaatcc tgtctttttt
    19981 aaaggtggtc aagtcatttg tcgagagcga aaagagagat ggatgttaat tgttaaatta
    20041 gatcagcaac gacagtatca gtttgaatac cttaaaccca aacaatatag tcaataaata
    20101 gtattgttgt cataaatcct taaaatgatc caatatatag taattaaagg tgacacttct
    20161 tttcatttca agtgtaattt ggtatgataa ggttatgact tttgaaaaaa ttgaagaagc
    20221 ttatcagctg ctcttagaga actgtcaact aattgaaaat gatctaaaaa cacatatata
    20281 cgatgccatt gttgaacaaa actcctttta tttaggggct gagggagcta gtcctcaagt
    20341 tgctcaaaat agtgataaac tgaaagcctt gtgcctgaca aaagaagaat ggcgtaaggc
    20401 ctaccagttt ctttttatta aggcagctca gactgagcaa ctccaagcca accatcagtt
    20461 cacaccagat gctattggct tcattctgct gtatcttttg gaacaattga gtgataaaga
    20521 tagcttagag gtacttgaga ttggaagtgg aacagggaac ctagcccaaa cccttctcaa
    20581 caacacgagc aagagccttg attatgtagg gattgaactt gatgatctct tgattgatct
    20641 gtcagccagt attgctgaga taatggattc ttcagctcat tttattcaag aagatgcggt
    20701 aaggcctcaa ttactaaaag aaagtgacat tgtcatcagt gacttaccag ttggttatta
    20761 tcctaacgat gatattgcca aacggtacaa ggtagctagt tctgaggaac acacctatgc
    20821 tcatcattta ctcatggaac aatctttaaa gtatttgaaa aaagatggtt ttgccatttt
    20881 cttggcacct gtcaatttgt tgacaagccc tcagagccag ttattgaaac agtggttaaa
    20941 agattatgct caggtggtga ccttgattac gctaccagat tctatatttg gtcatccctc
    21001 taatgctaag tccattattg tcttgcaaaa gcagacagac catccgatgg aaacctttgt
    21061 ttatcctatt cgagacttga aacttgcaga gaatattcat gactttatgc aaaatttcaa
    21121 aaaatggaaa caggataatg tcaattaact gattttttgt tataataaaa tagcatcata
    21181 gaaaacgatt tcaagagagg ttaaaaatgt ccaagacaat tgcaattaat gcaggtagtt
    21241 ctagtttaaa atggcaactt tatcagatgc cagaagaaga agtgttagca caaggaatca
    21301 ttgagcgtat tggtctcaaa gactctatct caactgttaa gtacgatggt aaaaaagaag
    21361 agcaaattct tgatattcac gatcatgccg aagccgttaa aatcttgttg aacgatttga
    21421 ttcattttgg tattatcgct gcttatgatg aaattacagg tgtcggtcac cgcatcgtcg
    21481 caggtggtga atactttaaa gaatcagttg ttgtcgacga tactgttgtc gaacaagttg
    21541 aagaattatc agccttagct ccacttcaca atcctggagc ggcggcaggg attcgtgcct
    21601 tccgtgatat tttgccagat attaccagtg tttgtgtgtt tgacacatca ttccacacca
    21661 gcatggcaaa acatacttac ctttacccaa ttcctcaaaa atattatacg gattataaag
    21721 ttcgtaaata tggagctcat gggacaagtc ataaatatgt ggcagaagaa gctgcaaaaa
    21781 tgcttggtcg tccattagaa gaattaaaat taattactgc tcatattgga aatggtgtct
    21841 caattacagc taattaccac ggtaaatcag ttgatacctc aatgggattc actccattag
    21901 ctggtcctat gatgggaaca cgttctggtg acattgaccc agctatcatt ccttatttaa
    21961 ttgagcaagc cccagagtta aaagacgctg ctgacgttgt taatatgtta aacaaaaaat
    22021 caggtcttgg aggagtatca ggtatttcta gcgatatgcg tgatatcgag gctggcctac
    22081 aagaaaacaa tccagatgct gttttagctt acaatatttt cattgatcgc attaaaaaat
    22141 gcatcggtca atactttgct gttttgaatg gggcagatgc tttagtcttt acagctggta
    22201 tgggtgagaa tgcaccattg atgcgtcaag acgttattgg tggcttaaca tggttcggaa
    22261 tggacattga tcctgagaaa aatgtttttg gataccgtgg cgacatttca actcctgagt
    22321 caaaagtgaa ggtgcttgtt atctccacag acgaagaatt gtgcatcgcg cgtgacgttg
    22381 agcgtttgaa aaatacaaaa taaaagagac taagtctcaa tagattaacc aagtaaggca
    22441 acactttact tggtttttta agaggtttat ctgttagtta tggtgcctag gtattagttc
    22501 tgatcagtct ccttgctttt tgtaatcttg tgctaggcga tttggatgtc agccttattt
    22561 agaagttttt aattgcttca acgcttttct tgtatgtgtt tatagagccc aatgatctaa
    22621 aagactattt gataacgatt tatgatgagc gtaatcgtgc gattcgaaaa cagacacaag
    22681 tttactgctt ttacctgatg attgttctat ttgttgcctt attctttttc ttcccttgct
    22741 taaccattcg agatcttgtt tcttataagc tacctttgat ttttgcttac ctttacttga
    22801 ttatcagaag tctggtggct aagaaaatgg aggcactagg gaaaataaca actaatagtc
    22861 aaaaacctcc gtttgatacg agtcaggttc tttgttagat gacttgtcta acggttgagt
    22921 ttcctgtctg gtcaacggag gtgtttgtat tgttgtctga tttgtattgg ggcacttatt
    22981 ttacaagctt ttagccttat cgatggtttt gtcaatggca gagctgacag tagttgtgag
    23041 gccaaggcgt tctaactcca tcagaccagc aatagttgtg ccaccggggc tacaaatagc
    23101 gtcaatgaga tcgtgcggac tttgagaact ggtcttgaga ttgctggcgc tagccaagac
    23161 tgtttgagta acaatctcca gcgcctttgc tttaggcatg ccattcttga cgccagcctt
    23221 agccaaagcc tcaataaaga gataaatata ggcaggactt gaccctgcta aagcggtaaa
    23281 ggtgtcaaaa tccttttcac taatatcaaa tgtgctacca aagctatctg ttaagtctcg
    23341 aacacgtgct tgtaattcct gggacaccaa agcatttccc gttaaagcgg tactgctttg
    23401 gagaatttgt gcattcatgt ttggcatgat acgtagcagc ggaaggtctt gtcctacgaa
    23461 tgttgctagt cgttgaaggg aaatgcctgc tgccatagat ataataggct gtttgaagtg
    23521 aagcggtttg agtaccgttt caaatagttg aggcttgatg cctaaaataa caagatcaac
    23581 ctggtcaata aggtcttggt gggacatagc ataaggcagt gttaactgct ccgcaatttc
    23641 cttggaccgt tctaaagatg atcctgaaat gataagttca tggggtgttt gtttaaggcc
    23701 tttgatgata gtgctagcca ttttgccaac accaataatg ccaattttca ttctgttgct
    23761 ccttgtggga tattatggtt aatcaggcta acgctagttt agtaacgttt aatcaagtca
    23821 acggttgagc gatccagttt tttgataatg gcttgtaaga aggcttgggc ttctacgaaa
    23881 tcatccatag cgtagagggt ttgatgagag tgaatgtagc gtgcacagac tccgatagtt
    23941 gttgatggga caccatcatt ttgaaggtgt gcagcacctg catctgtgcc tcccttgcca
    24001 caatagtatt ggaaattgac accagcgtcc tcagcagtag tcagtaagaa gtcgcgcata
    24061 tctttgagca tgacatggcc tgggtcgtag aaacgcaaca aggtgccatc tccgattgtt
    24121 ccaggattgc cataaatatc accagcaggc gaacaatcta ctgcgaaaaa gagttcaggg
    24181 tcgaacttgg tggttgagac gtgggctccg cgcagaccaa cttcttcttg aacgttagca
    24241 cctgcaatta gggtgttgtt aaggtcttgt ccttttaacg cttcaagcat ttctgttatc
    24301 atgagaacgc catagcgatt gtcccaagct tttgaaataa tatttttttg attggctgtt
    24361 aggatcgttt cagattgagg gacaataata tcacccggtg taatgccaaa gctttcagct
    24421 tctgccttat ccgtaaagcc accatcaaac acaatatctt cgatatgtgg tagactagca
    24481 gagccatttg ccccacgtaa aaaatgggga ggtaccgatc ctgaaataag gggaataact
    24541 tggccagtgc gtgtgtaaag ggtaaaccgt tgtgaactga caacaagtgg gttccaacca
    24601 ccgataccaa ccacgcgtag cgttccgtca actttgatat cactgaccat aaaaccgact
    24661 tcgtccatgt gcgcagctac taaaatacgg ggggcttttt cagctttact atctctgata
    24721 ccaaaaatgc caccaagccc gtctgtttca acacggtcaa ccagcggggt tattttggtg
    24781 cgtaggtagt cacgaacgct atgttcatag cccgcaatgc catccagttc ggtaacttct
    24841 ttgatttttg agaataagtc tgtcattttt catctccatt taaaaggttt cagaccagtt
    24901 caacgcggtc atctccttat attctaccac tttttaagta agaatgggtt tcacagaaaa
    24961 gaaaaatccc agagactaga gatctctgga agaagtgttt gtcttttggc gataacctgt
    25021 ttttttaggc agcaaggaaa tcattaaaat gataaagcac aagctggtta ataagaatag
    25081 tagggcgctt aggatgcgaa aagactcttc actagcgaaa agtaaggata atggagtcat
    25141 aaggagaacc ttccatttta ggttaatcag tgatttttat agcgtggtta aattaataat
    25201 aaaccacacc taatcaacgt acctttagtt tagttgtttt tactattttt gtcaatacat
    25261 aacagtagaa atctttagtt ttcttatttc agatcgtcca atttgatctt tttatgataa
    25321 aatgagggat atgagtaaaa agaaaatagg tatgatttca ggtatctttg gatttagttt
    25381 agctattggc ctaggaatag ttatcaaaga ttattgccaa gacaggcagc gtcgacaaat
    25441 gacaagggat ttacgcacct ttttttcacc tttaggacaa atcgaagttt tatatatcaa
    25501 tccttgtcag gtcaaacaag attatatttc aggtggggtt gttatgtcaa acggcaaaca
    25561 gtaccaattc acctatcaca gtcgacaaat tagttttgag gaggacaagg gatgatcaga
    25621 ccgacttctt atgagtcatt agcggctctt attgaaaaag aagataagct ggtgttattt
    25681 tttacggcag actggtgtcc agactgtcaa tttatttatc ctattatgcc agaaattgaa
    25741 gcagaactta cagatatgac ttttgtttgt gttaatcgtg atcagtttat agaggtagca
    25801 caaaagtgga atatttttgg tattcctagt tttgtcgtga ttgaaaaagg tcaggaagta
    25861 gggcgtctgg ttaacaaaat gagaaagaca aaaactgaga ttatgcattt tttagctgct
    25921 tatcaataag aaaagaggaa gaataaatga tttttgcata caataaagaa caagttggcg
    25981 atgtcttgat ggttatctta caagacacca aagatatcaa acgtcaagta gaacgaaaag
    26041 gcaaagtagc ccgtgttttt gcagaagaaa gcggcaaaac ccttgcttgg aatatctttg
    26101 aagcgtcaag cttgattact attgaaggca atggacagat ttttttgaca gacgaggacc
    26161 ttgcaagatt aaatgcagag cttgctaagg aaggattttc agaaaggctt gaaccgactg
    26221 tgggacctgt ttttgtggtt ggtcaaattg ttgagatgtt ggctcatcca gatagcgacc
    26281 atcttaatat ctgtcaagtg gctattggtg aagatcaaac ggttcaaatc gtagcgggcg
    26341 caccaaatgc tgcgcttggt ttaaaaacga ttgttgcctt accaggtgct ataatgccaa
    26401 atggtagtct gattttccca ggaaaattgc gtggtgaaga aagttatggt atgatgtgct
    26461 ctcctcgtga gttagccttg ccaaatgcac cgcaaaaacg tggcattatt gaacttgatg
    26521 agtcagctgt ggtaggagaa gcttttgacc cagccaaaca ttggaaaggt cagaaaaacc
    26581 agctgaaata ggactgtatt taactaaatg accagaaaaa aggattagga gcccctagtc
    26641 cttttttctt atgttttcaa aaacgtttaa aatgaaactt attttaccac aatttttacg
    26701 aataataagg taaggaggtc agtatgtata ataaagtgat agcaatcggt cgtttggtag
    26761 ctaagccaga attggtaaaa acagctacgg ataagcatgt agcacgtctc tctttagctg
    26821 ttaatcgaag atttaaaaat gcttctggag agcgagaagc tgattttatt tcagttgttg
    26881 tttggggaaa gttagcagaa actctggttt cttatgctag caaaggtagt ttgatatcta
    26941 ttgatggcga acttaggacc cgcaagtatg ataaagatgg gcaagtgcat tatgtgacag
    27001 aagttctctg ccaatcattt caactgcttg aaagtcgtgc tcagcgcgct atgagagaaa
    27061 ataatgttac taatgatcta gttgatttag tcttagaaga agatactctt cccttttgat
    27121 agaggataat gcttctcatc agggttcagc tgattactga aatatatgat gaggtgatat
    27181 ccgagcaaca aaagtgtgac tagatacttc tgataaaaat aaaaaaacac cttacgagta
    27241 tgaacaaagt ttcaagtgct agatgttgga actttgttca tcataggaat agtagggtgt
    27301 tttttagtgt attacttctt tttgttgcta gtgttaaggt ttacttgctt acaagcggtt
    27361 atcaggccac tagaactctt ataataaatg gagctctttg agtttggtgt caatcatttt
    27421 taagacagtc gccaaatctt gtgggttttg aacgaaatca agggaattgc catcaatttt
    27481 catttttgga gagaccttgt agtcttcgta ccaggttggg tattcaccgt ggacttgatg
    27541 gtaatattgc tcaagactag gattgccgtc gacctgctca aaatttcggc cacgtttttc
    27601 aatgcgctca agcattttgt caaaagacac atcaatgtag atgagaagat cagggcgttt
    27661 tttaggcatg ccttctagtt cttctaacat gttggcgaga agttcctgat agatgtcaag
    27721 ttctgtctta gtgacattgc catttttgta gttaagtttt aagaagagtt cgtcttcaaa
    27781 aatagagcgg tcaagaatgt tgttatcggc ttgataagct tctttgatgg acttaaaccg
    27841 tttattcaaa aaataaattt gaagtaaaaa ggcgtatttt ttagggtctt ggtagtagag
    27901 gtctagcacg gggttattat caacagcttc gtaaaaaacg tcagttccta aatgctctcc
    27961 aagtgcagca gcaagcgagc tcttgccagc cccaattgtt ccagctagta caatcaacat
    28021 gcgtctcctt ctaatgtcat tagcgtactg tttcgaagat ggcttcaacc tcagctagag
    28081 tctcagcgcg tgaaacagca ccacgaactt tggcagcacc tgctgttccg cgaagatagt
    28141 gtggtgctaa gccccgaaat tcccgaacag caatggtttc acctttgagg ttaatcaggc
    28201 gtttaaggtg gtctttggcg atgtctaatt ttttggcaaa gggaagatca gtcaattctt
    28261 gaccagtttc aaagaaatga ttgatttggg taaaaagata aggattgttc atagctgcgc
    28321 ggccaatcat cacggcatct acaccgattt cttcaatcat aaatttggcg tcttgcaccg
    28381 aacgcacgtc cccatttcca ataaagggaa tcttagtgat agccttagaa actcgggcta
    28441 atgtctcatg gtcgcaggtt cctgtataca tttgctcacg ggtacgaccg tgcatggcaa
    28501 gagcagatac gcctgccgac tcagccgcaa gggcattttc aacagcaagt gaactatccg
    28561 cccaacctgt acgcattttg acagtcagtg gaatatctaa aacagacgtg acttccttga
    28621 caatgtggta aatcttatca gggtcacgga gccacttggc accagcctcg tttttgacaa
    28681 ctttattaac agggcagccc atattaatat caacaatatc ggccttggta ttggtttgaa
    28741 tgaaatcagc tgcacgtttc aacccttctg cgtcaccacc aaataattga atggacatag
    28801 ggtgctcatt ctcgtcaata tggagcatgt gaagggtctt ttcgttgttg tagagcagcc
    28861 ctttttcgga aatcatttcc ataaccacca aaccagcacc aaattctttg gcgatggtac
    28921 gaaaggcaga gttggtcacg ccagccatgg gagcaaggac agtgcggtga gggatttcca
    28981 catcaccaat cctaaaggaa gaattaagct ttatcattga tgatggcctc caaatcactt
    29041 tcattaaatt ggtacttggt accacaaaat tggcaaacaa tctcagcacc cttatcttcg
    29101 tcaatcatgg cctgtaaatc tgcttttggc aaagtcatta gggctgcttc aaaacgttct
    29161 ctagaacagt cacactgaaa actcagaggt tcttcagaaa gacgtttgta aggttcatct
    29221 ccatagatgg cctccaaaag ggcatccaca tgatttttgg aagctagtag gtgagaaatg
    29281 gcaggcattt cttgtaggcg tttttcatag cgagcaatct cttcttcaga agctcctggt
    29341 agcacctgca ccataaagcc accagcaacc ttaaccttat cattttcatc taaaagcaca
    29401 ttaagtccga ttgcagatgg tgtttgttct gattcggtta agtagtaggc aaaatcctca
    29461 ccaatttccc cagtaataag aggcgttgtt gaggtgtaag ggttacctgt gccataatca
    29521 ataatcgtca caaaatgacc attccccata aaaggcccaa caaggacttc acctgttgcg
    29581 gtctttttaa tatcgacacc agtattttga atgtaacctt tcacatgtcc tttggtatct
    29641 gccacagaga taatgtgtcc aaaagaagaa tcaccaatca ctttgacggt gattttacta
    29701 tcgccttttt gattagccgc caaaatctgg ttggcgatca aggtacggcc aagcgcaaca
    29761 gtagacgatg acagcgtgtt gtgtttttct tgagctaatg caaccgtctc agtgctatca
    29821 aggacataag ccctaaaagc tcctgattgt gctattgatt taattatttt atccataact
    29881 tagattatag cataaagtgt aaaacttgta ttgacaggat tacttgaaaa atcaatacag
    29941 atagacagta aaaaatccca gagaatgact cgggattaag ttaaggtgtg gtctaaagtc
    30001 gcgcaatatg gtgacatggc gcttatgtta attgcttggt taaatcagct tggaattttt
    30061 cctctttaac ttgatacatc aattcttgga tagacagaat cgattcatca aaagatattt
    30121 cagcaacagc aattcctttt gtaagctcat gctgaacaaa aggaatcagt tggctgtgag
    30181 tgatgactaa atctggtttt aaatcaggaa tttgataaac attatcttgc aatagataat
    30241 aggaatgaaa atcaatgctt ttatccgaga aataccttgg aaaagaatcc gttaggagat
    30301 gagcattgat aaaattactg gctacgaaaa caacaactaa aggaggttgg atatttctta
    30361 gaatttgctc gacatagtgg caaaaaagat gaaaatgctt atggttcaag taacgcttac
    30421 caggaagttt ggccatccac tcttcgacaa ttaactttaa ggacgtatag agtttttggt
    30481 ttcctttata gtacggagaa acgaataagt tggtctcagg aataaaatgt tgcagattaa
    30541 acaagaatga ttttgaaaaa aacataagag cttttactaa actagccttt tgctctttta
    30601 ggttaggtaa aagagtgatg ataggattta aaagcaggcg aaaagtatca ttttcttcaa
    30661 aaagttgaca acattgtctg atatgctcag gtgtccattg taagctcgca aaagaattat
    30721 tagcggtgat ataaattaaa tagaggtagt ccaaatctcc tgctgaaaag tttagttggc
    30781 agtaagtttc gataatatca cggctacttt ttttcaaaga atcgtagaca aaaagttttt
    30841 ttaattgttg aaaaattctg gtttggggaa tagttaccga aaattgatgc cgcttccacg
    30901 ataaagccaa taaaatgtca tagaaagaaa acgattccga taaccaagga gaggttttaa
    30961 ggtgggtgga actatgggat aaaaagctat gaatagtgtt tttgtcttgc tgcgtcaagt
    31021 cataaacttt aatgccaaac ttactatata gcagagcgat gaggtaacgg atgcgatatt
    31081 cctcaccgac aatcttgttc ttagagagtt ttaattcaaa gtttcttaat aaaggaatca
    31141 atgcttcgcg catccgataa gctgaggagt ttgataaaaa atgacttctt gcaaaatccg
    31201 taaggggacg agagtgtgaa ccatttttta ttaaaaaggc tagtaattgt aagacattag
    31261 atgatgcata gagttggtaa agataagttt ctttaaaagg atgtgtaaat tggcaagata
    31321 tcatcctttt ttggatggtc atagacagac taccagggaa aaaggcattc agttcctcac
    31381 aataatggtt tagttgtaaa aaggttaagc cagttttttc tgctacctca gttattggca
    31441 aataagatgt cttaaaaaac aagacaacta actgacattt tgattcgatt gatgattcca
    31501 agtatttttc tatcaaggaa aggggtcctc tcttcctaca cttagaaagc caaataagtc
    31561 tttgataagt gtattctcct atttcaattc tatctaagct aaaaatagaa atcaaatcta
    31621 atggtttttg gtgaaaagtc gaaacctttt gaaatagctt taaagcaata ttttctcaaa
    31681 aaatcatttt caaaaacact aatttggtga aatatacaat caaaaaaata tctttcttga
    31741 caataacatg gtaagctcat atatgtttgt gagaggagag aaaatgaata acaaaatgtt
    31801 tttgaataaa gaagccggtt ttttggcaca cacaaaaaga aaaaggcgat ttgctgtcac
    31861 tttagtggga gtctttttta tgcttttggc atgcgcgggt gctatcggtt ttggtcaagt
    31921 agcctatgct gcggatgaga agactgtgcc gagtcatagt agtccaagtc ctgattttcc
    31981 ttggtacggt tatgatgctt atagcggatg gataccccgg tatcatgatc ttaaagtcaa
    32041 tttaaaggga agtaaggaat atcaagttta ttgttttaat ttaaaaagaa gctttcctcg
    32101 ccgcactcat agtattacaa ataattttta caagaaaatt gttgggagtg gatcagtgtt
    32161 caaatcttat gcagagaatc ctagggtttt agatgagaat ttagataaat tagaaaaaaa
    32221 tatactgaat gtaatttata atggatataa aagtaatgca aatggtttta tgaatggtat
    32281 agaagatttt aatgctatac tagtaaccca aaccgcaatt tggtattatt cagatagctc
    32341 cccagcatct gcaactgcag ttgaaaagat gtgggacaga gaagttaagg atggggatat
    32401 ttccttggag caagtgaaac taatgcgtga ggcattgaaa aaactaattg atcctaattt
    32461 agaagctact gcagttaata aaatcccatc aggatatcgt ttaaatatct ttaagtctga
    32521 aaatgaagat taccaaaatc ttttaagtgc tgaatatgta cctgatgatc cccctaaacc
    32581 tggtgatacg tcagaacata atcctaaaac tcccgagttg gatggtagtc ctattcccga
    32641 agacccaaaa catccagatg ataatttaga acctacattg ccgccagtga
//
LOCUS       DAUGSW010000016        31836 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUGSW010000016 DAUGSW010000000
VERSION     DAUGSW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31836
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.016"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..737)
                     /locus_tag="VIB18_000917"
     CDS             complement(<1..737)
                     /locus_tag="VIB18_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEQ8765935.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYN"
     gene            complement(757..3243)
                     /gene="gyrA"
                     /locus_tag="VIB18_000918"
     CDS             complement(757..3243)
                     /gene="gyrA"
                     /locus_tag="VIB18_000918"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEQ8765936.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIDEINTDRENSISKNKDN"
     gene            3434..4417
                     /locus_tag="VIB18_000919"
     CDS             3434..4417
                     /locus_tag="VIB18_000919"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEQ8765937.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            complement(4576..5946)
                     /locus_tag="VIB18_000920"
     CDS             complement(4576..5946)
                     /locus_tag="VIB18_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEQ8765938.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGIDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(6187..7914)
                     /locus_tag="VIB18_000921"
     CDS             complement(6187..7914)
                     /locus_tag="VIB18_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765939.1"
                     /translation="MIKTDHHLLKRMLQDLLKKPLLVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WIMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            complement(7911..9635)
                     /locus_tag="VIB18_000922"
     CDS             complement(7911..9635)
                     /locus_tag="VIB18_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765940.1"
                     /translation="MKRLRPYLKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDPLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGEQK"
     gene            complement(9645..10244)
                     /locus_tag="VIB18_000923"
     CDS             complement(9645..10244)
                     /locus_tag="VIB18_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEQ8765941.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            complement(10245..11222)
                     /locus_tag="VIB18_000924"
     CDS             complement(10245..11222)
                     /locus_tag="VIB18_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEQ8765942.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            complement(11229..12485)
                     /locus_tag="VIB18_000925"
     CDS             complement(11229..12485)
                     /locus_tag="VIB18_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEQ8765943.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            complement(12475..12927)
                     /locus_tag="VIB18_000926"
     CDS             complement(12475..12927)
                     /locus_tag="VIB18_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8765944.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLMALESQA
                     RQEGIAFIRLSSASHCKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            complement(12945..13535)
                     /locus_tag="VIB18_000927"
     CDS             complement(12945..13535)
                     /locus_tag="VIB18_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEQ8765945.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPNHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            complement(13519..14358)
                     /gene="prmC"
                     /locus_tag="VIB18_000928"
     CDS             complement(13519..14358)
                     /gene="prmC"
                     /locus_tag="VIB18_000928"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEQ8765946.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            complement(14358..15437)
                     /gene="prfA"
                     /locus_tag="VIB18_000929"
     CDS             complement(14358..15437)
                     /gene="prfA"
                     /locus_tag="VIB18_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEQ8765947.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            complement(15472..16041)
                     /locus_tag="VIB18_000930"
     CDS             complement(15472..16041)
                     /locus_tag="VIB18_000930"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEQ8765948.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPDI"
     gene            16179..16364
                     /locus_tag="VIB18_000931"
     CDS             16179..16364
                     /locus_tag="VIB18_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEQ8765949.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            16417..17352
                     /locus_tag="VIB18_000932"
     CDS             16417..17352
                     /locus_tag="VIB18_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEQ8765950.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETDMLSLTVMAPSSLDCEIWTTRLFGLDKATV
                     ISCLNSLKHIEGLVVTKDQKIWMSKGLRPYFQALY"
     gene            complement(17494..18756)
                     /locus_tag="VIB18_000933"
     CDS             complement(17494..18756)
                     /locus_tag="VIB18_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEQ8765951.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGVM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLLLK"
     gene            complement(18756..19337)
                     /locus_tag="VIB18_000934"
     CDS             complement(18756..19337)
                     /locus_tag="VIB18_000934"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEQ8765952.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     regulatory      complement(19424..19519)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(19642..20625)
                     /gene="guaC"
                     /locus_tag="VIB18_000935"
     CDS             complement(19642..20625)
                     /gene="guaC"
                     /locus_tag="VIB18_000935"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEQ8765953.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAGQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAYEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHFESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     gene            complement(20903..22429)
                     /locus_tag="VIB18_000936"
     CDS             complement(20903..22429)
                     /locus_tag="VIB18_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEQ8765954.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVAMMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKIGLIQK
                     "
     gene            complement(22422..23150)
                     /locus_tag="VIB18_000937"
     CDS             complement(22422..23150)
                     /locus_tag="VIB18_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8765955.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENITIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVVNLFGGDEHA"
     gene            23570..24259
                     /locus_tag="VIB18_000938"
     CDS             23570..24259
                     /locus_tag="VIB18_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEQ8765956.1"
                     /translation="MKNAISILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     QSNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLNTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            complement(24453..25208)
                     /locus_tag="VIB18_000939"
     CDS             complement(24453..25208)
                     /locus_tag="VIB18_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEQ8765957.1"
                     /translation="MGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(25335..26330)
                     /gene="pta"
                     /locus_tag="VIB18_000940"
     CDS             complement(25335..26330)
                     /gene="pta"
                     /locus_tag="VIB18_000940"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEQ8765958.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            complement(26334..27239)
                     /locus_tag="VIB18_000941"
     CDS             complement(26334..27239)
                     /locus_tag="VIB18_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8765959.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            complement(27236..28072)
                     /locus_tag="VIB18_000942"
     CDS             complement(27236..28072)
                     /locus_tag="VIB18_000942"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEQ8765960.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            complement(28047..28718)
                     /locus_tag="VIB18_000943"
     CDS             complement(28047..28718)
                     /locus_tag="VIB18_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8765961.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            28806..29384
                     /locus_tag="VIB18_000944"
     CDS             28806..29384
                     /locus_tag="VIB18_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEQ8765962.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFANSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHIAFKYAKSKVARCINTLKKFNDK"
     gene            29524..30504
                     /locus_tag="VIB18_000945"
     CDS             29524..30504
                     /locus_tag="VIB18_000945"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8765963.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAADVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            30501..31628
                     /locus_tag="VIB18_000946"
     CDS             30501..31628
                     /locus_tag="VIB18_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8765964.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALTHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            31618..>31836
                     /locus_tag="VIB18_000947"
     CDS             31618..>31836
                     /locus_tag="VIB18_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8765965.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAI"
BASE COUNT         9823 a         6603 c         5552 g         9858 t
ORIGIN      
        1 tggttataag aatgattaaa agctttcaat acatcggcgg gcgctttatc aaaatcgtat
       61 tctgttttta gttctccttt gacaataata cgttctgttg cttcgatatc tgtacaagtc
      121 actaaagtca cttctttgag accagctgta tcatcgataa catcaacgcg ttcaggagct
      181 accgtgaaaa catcttttat gatgtattcg taaatttttt ctttatctgt taaatagatg
      241 gacatcccat tttgtgctct ttcaagcggc gaaaagagca tttgagatga acctgtaatt
      301 ccaaaaatat gatgactggc aagagaataa ttattttctc ctcccataac ttgttcttct
      361 ttcatcgttc ctgcgccata aataagctca gtatttccta aacctttaaa aattggtaaa
      421 ttaatgccaa gctctggtat ggcaatgccc cctataacag gaagttgctg agccgccatt
      481 tgtgcttgca agacactctc tgtactaact ggctctacgg cttggaaatc aaatgttgac
      541 ttagcctctt tattcttttt gatttgtttt ttcgaaactt tcgttacttg atatttatta
      601 gagtttcgag caattaatgt atttcggata ggtttgttaa aaagcaatgc taaacctaga
      661 attaaaagta cagctattag tagttttctt gcccaagaca tggattttat ttttcgacgc
      721 ttttgttttt ttaccatttt ttactccttg ttatgattaa ttatctttat tttttgaaat
      781 actattttca cgatcagtat tgatttcatc gatactactg tcttcaggct gaaccaaggt
      841 aaatgttaca atcttagcat cagcatctag tttcataatt ttaacaccca aagtagcacg
      901 acctgtttgc gaaatatttg caacatttgt gcgaataatg acacctttat ttgtaatcac
      961 catgatatct tctgtaccat ctacggtaac caatccagct aattgaccat ttttaggggt
     1021 aatattagct gtttttattc cttttccccc cctacctttt gtaggatagt ctgtagcact
     1081 tgttctctta ccaaagccat tttcggtaat tacaagaact tcttggttat cttgaatacg
     1141 tgacgcgcca acaacgcgat catcttcacg aagcttaacc ccgcgaacac ccgtagctga
     1201 tcggcccatg ttgcggatgc ttgcttcatt aaaacgaaca gaatatccgg aatgagttcc
     1261 aatgataatg tcatcctgac cgcttgtcaa aaggacgtta atcagctgat ctccctcttt
     1321 caacttaaga gcacggagac cgttttgacg gatattatta aattctgaaa cttctgtacg
     1381 tttgacaatg ccttgtttcg ttgtaaagaa gaaggattta cctgctgttt cttccttacg
     1441 tgcgttgata atagtttgaa tggtttcacc atcttctaat ttcaatagat taacaattgg
     1501 aagacctttt gctgtacgac catattctgg aatttcgtaa gctttcaacc gatagacacg
     1561 cccaaaattc gtaaagaaga gcaaagtatc atgggtactt gttgatacca attcacgtac
     1621 aaagtcgtca ttgttgactc cagttccttg gacgccacgt ccaccacgct tctgggcacg
     1681 aaattcatct tgagcaagac gcttgatata acctttattt gacaaggtaa tcaaaacatc
     1741 ttcttcttca attaggtctt catcttctag agaaaggact tcaccgacca ttaattctgt
     1801 acggcgtggg ttagcgtatt tacgcttgat ctcatccatt tcttctttga tgatagtgat
     1861 aatacgttct ggtttggcta aaatatcaga taagtcagca atcaaggcca acaaatcatc
     1921 atattctgat tgaatcttat cacgttccaa accagtcaaa cgacgcaaac gcatatccaa
     1981 aatagcttgg ctttggcgtt cagacaagtc gaaacgtgac atcaattctg tctgagcaat
     2041 gacatctgtc tcgctgttac gaataatagc aatcacttcg tctaaatgat caagggcaat
     2101 cagtaagcct tctaaaatat gagctctggc ttcagcttta tctttatcaa atcgggtgcg
     2161 acgtataata acttcttttt gatgactaat gtaattatca atgatttgtc tgagtgacaa
     2221 tattttaggc acaccatttt caatagccaa catattaaaa ctgaaattcg tctgaaggct
     2281 tgttaattta aagaggttat ttaagataac tgtcgcggat gcttctcgac gaatctcgat
     2341 aacaaaacgc actccttcac ggctagattc gtcacgaact gctgtaatac cttctagtct
     2401 tttttcttgt gctaaacgaa caatgtgttc atgcactttc gttttattga cgccataggg
     2461 aaattcagta accacaatac gttcccgacc tgtttgagtt gtttcaattt ctgttcgaga
     2521 gcgtaaaacg atagaacctt taccagtatc ataagcccta tgaatacctg agcgccccat
     2581 aacaagggca ccagtcggaa agtcaggtcc agggatcact tccatcaact ctcttgttgt
     2641 acagtctgga tgttccatta ccatcttgac agcgtcaata gattctgcca aattatgagg
     2701 cggaatgtta gttgccatcc caacggcaat ccctgtcgct ccattgacta ataaattagg
     2761 aaagcgagct ggtaatacta ctggttctct ttcgcttcca tcgtagttat cttgaaaatt
     2821 aacggtattt ttattgatat cccttaataa ttcaagcgca attttactca tgcgcgcttc
     2881 agtataacgt tgagcggcag caccatcacc atccatagaa ccaaaattgc catgcccatc
     2941 aacaagcata tggcgataac tccaccactg agccatacga accatagctt cataaataga
     3001 agaatcccca tgcgggtgat atttacccat gacatcaccc gtaatacgag cagatttttt
     3061 atgcggttta tcaggtgtca caccgagttc attcatccca tagagaatac gacgatgcac
     3121 aggtttcaga ccatcacgca catctggcaa agctcttgcc acaatgacac tcatggcata
     3181 gtcaatgaaa ctcgttttca tttcacttgt cagattgacg tcaattaaat ttcgatcttg
     3241 catttaagga atgctccttt tctagtcaat actagatttc attataccat aaattcctta
     3301 ttttttctta ttggaagcgt tatcagtaaa ctattttcat tatttttctg aattcaatga
     3361 caaacaatta tcaatatgtt aaaataagac cgtatgagct tttgctctaa taaaattaag
     3421 gagatgttta gaaatgactg caactaaaca acacaaaaaa gtaatcttgg tcggtgatgg
     3481 tgccgtcggt tcatcatacg cttttgcatt ggtaacacaa aatattgctc aagaacttgg
     3541 tattattgat atttttaaag aaaaaactca aggagatgca gaagatttaa gccacgctct
     3601 agcttttaca tcacctaaaa aaatctatgc agctgactac tcagactgtc atgatgctga
     3661 tcttgttgtc ttaacagctg gtgctcctca aaaaccaggt gaaacacgcc ttgaccttgt
     3721 tgaaaaaaac cttcgtatca ataaagaggt tgttacacaa atcgttgcat ctggtttcaa
     3781 aggaatcttt cttgttgctg ctaacccagt tgacgttttg acttactcaa catggaaatt
     3841 ctcaggtttc cctaaagagc gtgtcattgg ttcaggtaca tctctagatt cagcccgttt
     3901 ccgtcaagct ctggctgcta aaatcggtgt tgatgcgcgt tcggttcacg cttacatcat
     3961 gggagaacac ggtgactctg aatttgctgt ttggtcacac gctaacgttg ctggtgtagg
     4021 tctttacgac tggctccaag ctaatcgtga cattgatgag caaggcctag ttgatctttt
     4081 catttctgta cgtgatgctg cttactcaat catcaataaa aaaggtgcta ctttctacgg
     4141 tattgcagtt gccctagctc gtattacaaa agctattctt gatgatgaaa atgctgttct
     4201 tccgctttct gttttccaag aaggccaata cgaaggtgtt gaagattgct atattggtca
     4261 accagctatc gttggagcgt atggaattgt tcgtccagta aacattccac ttaacgatgc
     4321 tgaattgcaa aaaatgcaag cctctgcaaa tcaattgaaa gctatcattg atgaagcctt
     4381 tgctaaggaa gaatttgctt ctgctgctaa aaactaatca caaaagagac ttcggtctct
     4441 ttttgttttg cctgatattc cttttccaac gtgctataag agtataatca taagtttaga
     4501 acttttcggg ttgcaacaat taaaaagcaa aaaagccagt gctgctgaac tgctctggct
     4561 ttttcctatc agatactagt ctttggcacc aagtgctgcc attgtgatgt agttgtaagg
     4621 tttgttgaaa tgtggtaaga agaaaatatc agttaatgcc aacttttcaa tggtcactcc
     4681 ttcttggata gcaagtgaga acatgtgaat tcccattgac atatcttcac gggctgccat
     4741 ttgagcaccc aagatacgac gtgagtcttt atcgtaaaca atcttaatgg ttactgggaa
     4801 gttaccgtgt tcgataaatt caggtttttg gttatcagta tactcagtca ctgcagcatc
     4861 aaaaccaagt cgttttgctt tttcaagtgt caaaccagtt gataccatgt gcaagccgta
     4921 aatggaaata ccgtttgagc cttggacacc gattccttca aggtctatac cacaagcgtt
     4981 atgtgctgct acaattcctg tacggacggc atttgaagct aaagcaatgt agtttgtatc
     5041 gcgagtagca ttatcgtaga tagttgcaca gtcaccgata gcataaacac ctggaataga
     5101 agtttcttgg cgtttattga caaggaaagc accattacgg aaaagatcaa tcttaccatt
     5161 tccaagagtt gtgtttggac ggaaaccaac ggcgaggata accatatcca catcgtactc
     5221 atttttgtca gtaatgatct tttcaacctt accattacca gctacttctt taactgtttc
     5281 accaaaggct agttgaatac catgttcttc catgttttta gccattaagt cagtcaaatc
     5341 acggtcgtaa taacctgcca agcaagtgtc cacgacatca atcagaacca cttctttgcc
     5401 tttgcgttgg aaagcttcag ctaactcaac accaatgtaa ccagcaccaa ctacggctac
     5461 acgtttaatg tctttgtttt caagctttgc aatcacatca gctgagtttt ggtataactt
     5521 cacaaattga agattttcaa gagttgcttc aaattcaagt gatccttctt tgatttcggc
     5581 acctttaatc ggtggtaaga taggttgtga gccagttgca aaaatcaact tgtcgtaagt
     5641 ttccacgtgg tttttaccat caacaagcgc tgtcactgtt ttggcatcgt agtcgattga
     5701 ttgaacaggt gattccatgt aaactttagc ccctaaagac tctaattctt ctttatctga
     5761 atagaaaagt ccttctggtc cagcaatttg ctcaccaatc caaagtgcca taccacaacc
     5821 taaaaatgaa atatttgagt tttggtcaaa tacaacaatc tcattagcat caccgtagtt
     5881 tgttaacata gtcttgatac aggccgtacc agcatggttt gcaccaacaa caacgatttt
     5941 actcatatat tttgttcctc atttcacaat attatatagg gctctattat accacagtca
     6001 aaaaacgctt ccaaatatat tgctcacttt tttgagttat ttcttcttta gtcaactgtt
     6061 ttttctcact tataaaaaaa gatcgtccgc tttttcgctg ttattttttt atataacagc
     6121 ttaaagtttg ttaattaact aactttagga agacttaaaa agttcacctt tgttaaaaga
     6181 cgaactttat tctatctttt gtaatctagc ataacagccg ttttttgaca ttaagctggc
     6241 atgtgttccc cactcaacca atcgaccttg atccataaca agaatcaaat cagctgattg
     6301 aatcgttgat aaacgatggg caatgataaa gctggtcctt cctctcatga gttcttttag
     6361 tgcctcttga ataacagctt ctgttctaat atcaatagag gaggtggctt catctagaat
     6421 caagactttt ggttttttca aaaacattct agcaatagct aataactgga gctgcccttg
     6481 ggacaaagca tcatcagaag cacttaagta agtatcataa gtcttaggaa gctgcataat
     6541 aaagaagtgt gcatgggctg ctttggctgc tgccactact tcatcacggc tagcctcttc
     6601 actgccgtaa gcaatcaact catgaacagt cgcatctttc aaccaggttt cttgcaatac
     6661 catgccagta atggacctaa gttcttcctt agcataacac ttaataggaa ctttatctaa
     6721 cttgatgcta ccagcatcaa gttcataaaa gcgcatgagt aaattgatta aagttgattt
     6781 gcctgcacct gtaggcccta caatcgctac cttggaaccc gcaggaacag aaaaattaat
     6841 atctttcagt aagggcctgt ctttttgata agaaaaactt acttcttcaa agtcaatttg
     6901 ccccttaacc gctgatgcct taaatgttag aaagtgctct tgctctttta tttcaatatc
     6961 taaaaggtca taaagccttt gcgcacaagc taaagaactc tgtatctctg ccaagacaga
     7021 tgaaatatcg ttgaaaggtt tggtatattg gacaacaaca tttaaaaaag tggttagctg
     7081 acctactgaa aaaagtccag ccatgatacg aacagcccct aaacctgcca gtaaagcata
     7141 aatgacacta ttaataaagc gagtggctgg attgactgtt gaggcgtaaa aaatggcttt
     7201 ttgtgaagcc tcgcaatagg ttttatttaa aacatgataa tcacagatag actgctcttg
     7261 agcattaaac agttgaacca aaccttcttg acgaaggatt tcttcagtaa actgagctaa
     7321 atttcctctg cttttggtct gtgcttgtgc ataatgaaaa ctcttttgag caataaaacg
     7381 agctaaaaag agggagcttg gtgttaacac caaaaccaag attaacatga tccagtcaat
     7441 ctgtgccata gctataatgg tacacagaat cgtcaatagt ccaagtataa actggttaaa
     7501 aaccatttgt agaccattga tcagttgctc agtgtcggtt atcactcgac taaccaaatc
     7561 tccaatggtt tgacgatcta gatatgcaaa aggaagacga tgaatttttt ccaaaagctt
     7621 atctttcaat tgctggctat attgatatag caaacgacta tagacaagag gcatcaccca
     7681 ttgaatcaat gtgttgacca caataacaac taacatttgc cccaacagcc attttaaagt
     7741 ttgccaagaa ttgactgaca aactcatatc aacggcttta ccgataagaa caggcaagta
     7801 aacacttaaa ccaacttgta caaaactagc tatcacgaga atacaaacaa gtagaggttt
     7861 ttttaacaaa tcctgaagca ttcgctttaa gaggtgatga tctgttttaa tcatttttgc
     7921 tcccccttca cgtaaagcgc tagcatttct tgataaagtg cattgcttac ttttaactgg
     7981 tcatgactgg caaaatccaa ttgatggccc tgttccaaca ctaaaatctt atcagcaaac
     8041 tgcaaattct taatagattg cgtgactaga atcactaaaa catctgataa ctcttctttt
     8101 agagctttaa aaagtcgtcc tcgagtctca ttgtctaagg cggaactggc atcatccaaa
     8161 atcaaaatgg gttttggctt cagaagtgct ctggcaatag ctagacgttg ccgttgccct
     8221 cctgaaaaat gacggccgaa ggcttcaaca ggtgcctcta attgttctgg taaggcagcg
     8281 acaaactctt ttgcttgagc caattcaaga gcccgccaca gttcctcatc actaataggc
     8341 attgattgtc ccagtaggag gttacttcta atcgttcctt taaataattg agctttttga
     8401 ggaacaagag caatcacatt tcgccactcg gttagtgttt ttggcacttc tccttgccaa
     8461 ttaagactaa tctcaccact atattgtgaa taagtttggc agatcaagtc aatcaaagtc
     8521 gttttgcctg ctccagtacc accaatgatg ccaatccatt ctccctgatc agcacttaac
     8581 tgaatatcat acagacttgg ctctgctgct cctggataag taaaggtcaa gtgccggatg
     8641 gtcaacagat gagttgaaat aggaccatct ttaagtaagg gcaaaggcgc ttcatcagct
     8701 aaaacaaaca cctgattaat ccgttttgcg gctgttacac tttgattgat ggttcccatc
     8761 aacatggtca ttttcaaaag ttctgccaaa atctgcaaga ggtaattaat taaagcaacc
     8821 aacatgccct gactaagcga tctatgagct acttgccaac ttccttgcca aatcaagatt
     8881 aacagggtaa gattgaccac taaaaaagtc ataggattca agacattggc tagggtagca
     8941 gcttgatatt ggtggcgact taagagcata ttttgctgct taaatgcttg gagttctttt
     9001 tgggtttgat taaaagcctt aattactcgg attccttgta actgttggct agtcaaacga
     9061 accaagtgat ctgtttctcg gcggattaag agataaaggg gacctaataa atgtgacata
     9121 acaaaaacaa gtgttagtaa gacaatcacc atcatcacaa accatagggt tagacttgga
     9181 ctaatccaat aagccattac catagcacca catacgataa taggggccct tagaaaaaga
     9241 cgcaaaaatt gattgatacc agtttgaatt tgaaaactat cactggtcaa tcgtgataac
     9301 agactagcat aaccaagagg gtcttggtcc tccttgctca aaaacatgat ttttttaaac
     9361 aaatcatctg tcatttgtct tgtaaaacca acagctgctt tcgaagaaaa atactgggct
     9421 gtaacggaaa gcaataagcc aatggttgct aaaccaaata atgttaaaac aaccctcaaa
     9481 attccctggc tgttgtgttg actaatcgat atatcaatca tgttagcaat taacaaaggg
     9541 actaataatt caaataaagc ttctaataat ttaaaaagag gacctaagat actttctttt
     9601 aggtaccctt tcaaatatgg acgtaatcgt ttcatgataa ctttctaaaa aaggctcatc
     9661 agttcaatta aataaagatt gaaatgaact tctcgtgagt aatagatatt gccgccattc
     9721 ttataaagct tacctccaga aatcaaggcg agggggtggt aataaaaata ggtttgacca
     9781 ctagtgttgc ctaggcttgg cgccacaacg gttttggaat aggtagtcgc taaatcaacg
     9841 gtattttgac ctccatgttt agcaatataa tcaatataag ctgttccaaa attataggcc
     9901 tgaacagccg tccaagaatc tactcctgct tcctcagcta gagcaagatt atgagacagt
     9961 aaattcaccc cgtgctcaat actggcctga ctatctgtaa tcgagttttt ttgtcctgaa
    10021 ctgctttcac tggattgcat gacatctgct tctcctcctt ttgtctcggt gtatatcata
    10081 gctaagacta agtctacatt tgcctttgta tcattttctg ctaatgtttt ctcaaccata
    10141 ggcttatatg ccaaaacacg ttgaacattg tgatgaataa caaaggattg gtaaatgaca
    10201 aaaagaagaa gaaaactgca ggcacgcttt aaaagtctaa acatctattt ggttttaata
    10261 tcctctatat ttttaatcaa gattgaataa gtcccatcat catttaacaa aaattcaacc
    10321 gcttcagcat cctgataaat ggcatttggt actgttaatt ctatcccgtt tgataacgat
    10381 agcttttgat tttctagttt ttttatctgt ctagaatgat caatatcgct aatttttata
    10441 ggttctggaa tgacatcttt gacttgatcc acaaaggtta aacgggctgt taaattatca
    10501 tcaaagagtt ggtcagctaa tttttctggt gataaaacgt cgtctgcttc taactgctta
    10561 aaaagagtgg atttcatctt tgactgaaaa gtaaaatcat cttgattaaa atgctctgca
    10621 attttttgag cggtttgttc tatcattttg atagactttt taacagattg ctcaggtgta
    10681 actttcaaga ggtgttctga aaaataatta gcaaaactgc cattatgctt cacacgcttt
    10741 tcaatcaagt agtactgacc agatttgaga ttaatgacta gtgcttcatc tggtgtctgg
    10801 gtgggactcg gcagattatt ctgcgtcacc gtaaatggat gttcataatt gtcagaaagg
    10861 tgagcaaact gttctttcaa agcaattcgc aagaaagcaa aaaagggttc gccatcctta
    10921 tcaaactgaa caaagactaa gtcattggtt ttttgatcct ctgaaataac aaaggcttcc
    10981 ttccataact gggcaatggt aacagacgtt tccaacaaat catcaccaat ggttgtaaaa
    11041 aaggtattat tagcctcaaa ctgaccacgt ttggcttcgt ccgagaacac tttggccaat
    11101 tttttccgga aatattcatc aattcgcggt gtaatgctca ctaaacgatc tgataacagt
    11161 aactcagtgt cattgggaga aaattgatga atgacaatac gttttatata actatctaac
    11221 atgattcctt actttttata gagtgggaag gcatcggtta actgacgcac ttcctgacgg
    11281 acttcttcaa gaatagtttc ttgatcatga ttaaccaagg ctttgatgat aagacgggca
    11341 atggtctgac tctctttaac acccatacca cggctggtta tggcagcaca accaatgcga
    11401 atacctgagg ttttaaatgg cgacaaggtt tcaaaaggaa tggcattttt attaagggta
    11461 atattaacct catccagaag attttgcgct agtttaccat tagcaataac cttagtgaca
    11521 tctactaaaa agacatgatt atctgtacca cctgagatca gacggaaacg atcatcttgt
    11581 gcaaaaactg ctgccatagc cgcagtatta tcaataatag cttgtgcata gtctttaaag
    11641 gctggatcca aggcttcttt gaaggcaacc gctttggcag caatcacgtg ttccagaggt
    11701 cctccttgta aaccagggaa aacggccgaa ttaatctttt tagcaagagc ttcgtcattg
    11761 gttaatatca agcctccacg aggaccacgt aaggttttat gggttgttga cgtcacaata
    11821 tgcgcataag ggacaggact cgggtgcaca cctgctgcta caaggccagc gatgtgagcc
    11881 atgtccacca ttaagtaagc acctacgtga tcagcaatgg cacgaaactt ttcaaaatca
    11941 atgcttctag agtaggccga agcccctgca acgataagct ttggctggac cgcctttgct
    12001 tgttctaaaa tcgcctcata atttaacatt tcagtatcag catctactga ataacccaca
    12061 aaatggtaag tttttccaga aaaatttact ggagagccat gcgtgagatg accacctgca
    12121 gccaaatcca ttcctaatac ggtatcacca gcctcaatta aggccatata agctgctgca
    12181 ttggcttgac ttccggaatg ggcttgaaca ttggcaaatg cggcaccgaa aagtttctta
    12241 gcacgttcaa tagcaagcgt ttcgacaata tccacacatt ctgttccacc ataatagcga
    12301 ttacctggat agccttctgc atacttattg gttaaaacag aaccttgagc tgccatgaca
    12361 gcttttgaaa ccatgttttc agatgcaatc aattcgatat gatgttcttg tctttcttct
    12421 tcagcatgaa tggcatccca aagctcttta tcaaagtctt caacattacc tttatcaaaa
    12481 atcattgtca tctccttgta agtttttgat gaatcgtaat tgtgttttat catctgcata
    12541 gtcgaggttt cggtaaaaag catgcgcttc tttacaatga ctggcagaac tgaggcgaat
    12601 aaaggcaatg ccttcctgcc tagcttggga ttccagggcc attagtaagg cactcccaat
    12661 tccccttctc tgataggctg gtaaaacagc caagcccaag agattaagac catcagaagc
    12721 ataaagggtc tcataacgtt cagcgtgaac atagcctaat aattgattgg tatccttgtc
    12781 ggcataagct aaaaaatagt gatggcaatc ctcaatcaat cgttcatatt gcctttctaa
    12841 caagtcaagc gaaactaaat agccaagggc tttggcgtta atttcttgta gcataggaca
    12901 gtccgtttta cttaatggtc tcaacattcc aagcggctcc tctcttaaaa gcgaagttca
    12961 ggcacgttgg ctaataattc ttctttggtg atagcacctt gacgtaaaat cacagcacgc
    13021 tcacctgata agtctaagat ggttgaatcc ttacctgtta gaaaaggatc atctgcataa
    13081 ccaaacactt gaaagtcaaa atcttgcata atatgatcaa aaactcgacc actagctttg
    13141 ccagataaat ttgcagaagg accaattaaa gggcctgttt tttgaattaa agctgcggta
    13201 attggatgat ttggtaagcg aaaaccaacc gttgaaagac ccgaattaat ccaataagga
    13261 acctggtcat tagcttttaa aataatcgtt aacggacctg gtaaaaaggc ttggtataat
    13321 ttcttgaggt atctcggctg ttcttttgaa aaggctaaga tactattaaa atcagccaca
    13381 ttaaggttca ttgctttatc tcggggtctt tgttttaagt cataaacagc atttactgct
    13441 ttttcatcta aagccttggc aaaaagacca taaaccgttt ctgttggtaa aacaagggca
    13501 tcacctgatt caatgatact agctagatac tccataatca acaaccacca tcctttcttt
    13561 gccaaatata tccgttacga ctcgtatatg tctttgagga aaataggctt gtaacatatc
    13621 ttttatacct tcagcttgct tataaccaat ttcaaagtaa agcttcccct ccttagttaa
    13681 gtaattgtca gcttgttcaa taatcttacg gtaaatagca tagccatttt ctttagcaaa
    13741 aagtgccaaa tgaggctctg attgcaaaac atttagactg acttcttcct tatcctcgta
    13801 ggatatgtag ggaggatttg acacaataat atcaaatgtt cctgaaatga gactaaaaac
    13861 atctgattca ataaacgtta tatcaagctg gtaagcatca gcattggctt ttgccaagtc
    13921 aagagcagct ctagaaatat cagatgccgt tacttgccag ttaggccttt cttttttgag
    13981 agaaatagca atcgctccac tacctgtacc aatatctaaa acattcaacg gtgcatcaag
    14041 attttcagct aaaatcatgt caactaattc ttctgtttct ggccttggaa ttaatacacg
    14101 cttgtcgact gcaagcttca aatcacgaaa ataagcatta cctgtaatat attgaggaga
    14161 taaatgctga cttagagaac agaaaatatg ttccaaaaga acagcatctt caggagtcac
    14221 agcttgattt tggtgaatca acatatctag acttgaccat tctttgattt ctctaaaaac
    14281 ataggcgaga ttttcgcgat cctcatctat ttgttctagt ttatcttcat aagttctgat
    14341 taatgtagca tagttcatta gttattgaga gattctaatt tctttgtctg atcatacata
    14401 acgagtgcat caataacttc atccattttt ccagataaaa tagtatctaa tttttgaagt
    14461 gtcaaaccaa tacgatgatc tgttacacga ttttgtggga aattataagt acgaatacgt
    14521 tctgaacgat caccagtacc aactgttgat ttacgttcag catcttgttc atcttgagca
    14581 atttgcgcaa aatggtcagc aacacgagca cgaatgattt tcatcgcttt atcacggttt
    14641 ttttgctgag tacgctcttc ttgcatttca actttgattc ctgtaggaat gtgtaccata
    14701 cgaactgcag tagcaacttt attgacattc tgaccaccag caccagacgc gtggtaaata
    14761 tcgacgcgaa ggtctttagg atcaatgtcg tattctactt cttcaacttc tggcattacc
    14821 aaaacagttg cagttgaagt atgaacacga ccctgactct ctgtcactgg gacacgttga
    14881 acacgatgag ctcctgattc atatttaagc ttagaataaa ctgactgacc agaaaccatg
    14941 gcaaccactt ctttaatacc accaacacca ttaacggatg attccataac ttcaaaacgc
    15001 catccttgag tttcagcata tttttgatac attgttaaaa gatcaccagc aaaaagcgct
    15061 gcttcatcgc caccagcagc accacgaatt tctaaaataa tgtttttatc atcgttagga
    15121 tctttaggta atagaaggat ttttaatttt tcttcatact cttctttagc tgcttttgat
    15181 tctttaagtt cttctttagc catttcttct aattcaggat caccactggc atctttgatc
    15241 atttcttcag catctgaaat ggtttgaatg acttgcttat attctctata agctgtgaca
    15301 gtttctcgag tattagcttc ttcacgtgat aattccataa atcgctttgt atctgaaaca
    15361 acatctggat cactaagtaa ctcacctaac tcttcataac gatcttcaac tgcctgcaat
    15421 tgatcataaa tattcatttt tctttgtatc tcctttaaaa ccgattacct tttagatatc
    15481 tggattaaaa taatgttttc gacaaactgg gatatatgtt tcattaccac caatttgtat
    15541 ctgatcacct tcatagacag gttttccgtt ttctgtcctt aaaaccatag ttgctttctt
    15601 actacagtat tggcaaattg ttttgatttc atcaatctta tcggccaata atagcaaatg
    15661 ttttgaacct tcaaaaagat tgttttggaa atcatttttc aaaccaaaag ccatgacagg
    15721 aacatttagc tcatccacca cacgcgccaa atcataaaca ttttgcttgc ttaaaaattg
    15781 gctttcgtca atcaggacac aataaggttt ttcctccaat tgggcaataa atgtgaaaat
    15841 atccatgtca tttgaaatgg ggatagcttc tcgtcgcata ccaatacggc ttgagacgat
    15901 gccaaaacca tcacgtgtat caagagcact tgtcataatg acaacaggtt tgccttgttc
    15961 ttcatagtta tgagcaactt ttaaaatttc aatggtttta ccagaattca ttgtcccata
    16021 tttataatag agttgagcca aagcggaaaa tcctactttc tatagtattc tacctatttt
    16081 accacaaagg ctgaagtttt cccagccatt gaaaacagtg tatacttttt cacagcatta
    16141 tgttacaatg atgcccaata acataaagga gtaacattat gccatttgta acaattgact
    16201 tgtttgaggg acgctcacaa gaacaaaaaa atcaattagc tcgcgaggtt accgaagtag
    16261 tctcacgcat tgcaaaagca cctaaagaaa atatccatgt ttttatcaac gatatgcctg
    16321 aaggaactta ctatcctcaa ggtgaaatga aacaaaaatc ataatgacct tcccccactc
    16381 cttagtgggg gtattctgct aaaaagagga ctaattatgt ttgttacgca acaattaaag
    16441 ctaatgggaa cagttattga tattcagatc gaatctgaca aagcttgcca acaactaagt
    16501 agagtcattg acttattata tacttacaaa aatcgttttt cagctaatga ttcaaactct
    16561 gaattgatgg ctattaatca ggcggctggt gttaaacccg tcagcgttca ctctgattta
    16621 tttaacctaa tccaaattgg taaagctcat agcttgtcaa caccaagtaa tcttaatatc
    16681 gccattgggc cacttgttca agcctggcga attggatttg aagatgctag agtgcctagt
    16741 cataacctta tctcacaaca gttagctcta acagatccta gacaggttct tatagatgac
    16801 aaaaaacaga ctgtcttttt acaacaagta ggaatggctt tagacttagg agccttagca
    16861 aaaggttata ttactgataa gattatggcc tacctgattg aagatggtat tgactctgcc
    16921 cttattaatt taggtggaaa tgtacgcgtt catggaccta atccgaaaag ccctgacaag
    16981 acttttcgaa ttggcattca aaaaccagat gctaaacgtg ggcaacatct tggtgtcatc
    17041 aaggttaaca atcactctgt tgtgacctct ggtatttatg aaaggcagtt tacagccaaa
    17101 gggaaacagt atcatcatat cttagatcgt cagacaggct atcctataga aacagatatg
    17161 ctcagcttaa cggtcatggc tccttcttct ttggattgtg aaatatggac tacccgactc
    17221 tttggactcg ataaagccac tgttattagc tgtttaaata gtctaaaaca cattgaagga
    17281 cttgtggtca caaaggatca aaaaatctgg atgtcaaagg gactaagacc atacttccaa
    17341 gccttgtatt agtaaaaaca actaggagtc tttctagcta actgattaaa cctatcaaaa
    17401 aaacgactct ctctgagtcg tttcaacttg aggacaaact tcatttttga ggtttgtctt
    17461 ttagtatgat cactgatatc ttaataatct ttactatttt aagagcaggt ttaagacaac
    17521 agatgtcaag gttgcgatca caataccatt cgttaagaac atttgagctg tctctggtaa
    17581 gctggcaaaa agattagtgc cattaaagcc taaacctgct gagatggaaa cggcagcaat
    17641 aataaaatta tactcgttct tttggaaatc aacacgatta agcatttgca ttccttgaag
    17701 agcaaccata ccaaagagaa caagcatagc tccaccaaga actgggcttg gaatcatttg
    17761 tgccattgct ccaaatttag ggagtaggcc aatgaccaca aggatacctg ctgcgtagta
    17821 aatcggacga cgggttttaa tacctgagat ttggacaagt ccaacgtttt gagaaaaacc
    17881 agtgtaaggg aaggtattaa ataacccacc gagaaagact gcgatccctt ctgagcgata
    17941 accattgcgc aaacgttttt catctaattg atcattagtc aaatctgaaa gcgctaagta
    18001 gacacctgtt gattcaacca tagaaaccgt tgcgatgata cacatcatca caatagaagt
    18061 gatttcaaaa gttggcatgc caaaataaaa tggggttggc acatgaatcc aagaagcctc
    18121 tacaacagga gttgtatcta ctaatcccat catggctgaa accaaagttc ccgctacaag
    18181 cccaatcaaa atggaaatgg atttcacaaa acctttggta aatttttgga ctaaaagaat
    18241 aatgacaatc gtcaacaatg ataacatcat gctttgtgcc gtaggctctt tgacgttatc
    18301 tcccatattc cccatagcaa cacctacgag acttaagcca ataacggtaa tgaccgatcc
    18361 tgtaacaatt ggtgggaaga aacgagcaat cttagaaaaa atacctgcca ctaaaatgac
    18421 ataaattcct gacgcaatga gggctccaaa catgacacct gaaccttgtt gcgctccaat
    18481 aatggataga ggtgccactg attgaaaagc acatcctaaa acaactggta atcccactcc
    18541 cgtatgcttg gttaacttta actgtaagaa agtagccaca ccacacatga aaatatctgt
    18601 cgaaatcagg taggtcaact ctctagcgga ataacctaaa gcacctgcga tcataattgg
    18661 tactaaaata gatccggcat acatcgaaag cacatgctgt aagccaagga cagctgattg
    18721 cgagtgagaa tgttcctgct ttgttgaatg tgtcattatg cgtcagcctc caagaagttt
    18781 agattgccat tttcaaagtt tttaatacgg gctaatgagg tcacttcaat gcccatatct
    18841 tcaatcaatc gacgaccatc ttggaaagat ttctcaatca caataccaac gccgacgact
    18901 tgtgcccctg cttgaccaat aatctcgatc aagcctttgg ctgcctgacc attagctaaa
    18961 aagtcatcaa taatcaaaac cttgtcttct ttagatagga atttaccagc gatagacacc
    19021 gtgctcgtca cttgtttagt gaaagaataa acttctgctg tcaaaatgcc ttctgtcatg
    19081 gtaatgtttt tatgtttttt cgcaaaaatc ataggaacat ccattgcttc tgcagcgtat
    19141 acggctggtg caatacctga agcttcgatt gtaaccactt ttgtaatgcc agcctcagca
    19201 tatttttgag caaacacttt accaattgct ttcatcaacc ggtaatcaac ttgatgagtt
    19261 aaaaaattat ctacctttag aatattctct cctagaatat tgccatctgt taagatgcgt
    19321 tcttcaagta actgcataaa tctccttttg attcaaatag aaaaagcctg ccgcaaagtg
    19381 agaaactctt atagtttctc actttgcaag gttaaaaacc aagcaagcct aaaagcttac
    19441 ttattgttag acattaaggt gtcttgtaga gacgctgcgc caattcacag cataaataag
    19501 tatgtcatta ttgaattcat tatgataatt tactatttta ccatgtttct tatttttttc
    19561 aatacctaca gagatatgat aaaagcatct ccagcattaa gctaaaaaat gctttactgg
    19621 tcctagctaa ctccatatca tttaaatgga atcaccattc caaatggaat ttttgacaat
    19681 aacataatca acatgacgca aactgtctaa atctttacca cccgcgtaag aaatggacga
    19741 ttgcaaatcc tgttgcattt cggtcagggt atctgataag tgaccttttg taggcaataa
    19801 gatttttttg ccttctacat ttttatgctc gcctttttga tattctgacg ccgagccata
    19861 atattcttta aacgtttcac catccacttc taccgttttt ccaggacttt caaaatgtcc
    19921 tgcaaaaagc gatccaatca tgaccatact agctccaaag cggatggatt tagcaatatc
    19981 accatgtgtg cgaatcccac catcagcaat gataggttta cgagctgcct ttgcgcacca
    20041 gcgcagtgct gctagctgcc aaccacctgt accgaaaccg gttttaactt tagtgataca
    20101 tactttgcct ggaccgatgc ctactttagt agcatcagca cctgcatttt cgagttctcg
    20161 tacagcttct ggcgtaccaa catttccagc aatgacaaat gtttctggta attcagtctt
    20221 gatatgctta atcatatcaa taacactgtt agcatgacca tgagcaatat caatggtaat
    20281 aaactcagga gcatcctctt tcaaagaagt cacaaattca tattcgtaag ctttaacccc
    20341 aacagagatt gatgcaatca agccttgttc atgcatgcgc ttgataaaag gtttgcggct
    20401 atcttcatca aaacgatgca taatataaaa ataaccctct tttgccaact gcccagcaat
    20461 tgtttcatca ataatggttt gcatatttgc tgggataact ggtagcttga actggtattt
    20521 tccgagtgtc acacttgtat ctgcttgtga acgactagta ataatgcact tgttaggaat
    20581 cagttgaata tcttcataat caaatacagg gatgtcatta aacataagtt tctcctcttt
    20641 agacacagat gaaagaaaat aagtcagttc tcatcttctt ctccacgtcc tttatacaaa
    20701 atgaccttcc tatgacctct gatgattaga ggcatcgcta ggtaaaaact tacctttcat
    20761 tttatagatt acttatttgt ttatattttg tcaaatttaa atactatttt taatttaaat
    20821 gttcggtttt tgtatttatg aattgttact tcttgaactt aagagacgaa aaaatgccag
    20881 tcctacggac caacatttct gtttatttct ggattaagcc tattttcaac agataatctc
    20941 gagcgacctt attagcatct gctcctttaa cagatacctc gtagttcatg tcctgcatct
    21001 ctttttcagt aatttttccc gctaattgat taagaatgcc ttttaattct ggatgttttg
    21061 ttaataagga agttttcatc aaaggagctc cctgataagg tggaaacaac tgtttatcat
    21121 cttttaaaac tttcaaatgg tatttcgtaa tttcagcatc cgtagagtaa gcatctgtta
    21181 cttggatatc tcctgattga attgcttgat aacgaagagc tggctccatc atcgccacag
    21241 atagctgtaa tccatattga gattgcattc ccttatagcc atctgctctg tccttaaatt
    21301 ccaaagtaaa accggccttt aaagtatcag catgcgcttt taaatcagaa atggtttcaa
    21361 tctgatattc cttagccaat ttttctggca tagcaacagc atacgtattt tggtaagcaa
    21421 atggcttgag aagggtcagt ttatcttgct tagcaatgcc ttttttagca tcctcataga
    21481 cctgcttagg gtcattagac aaaggtggtt tgtcgcgtaa aagacttgat gttatggttc
    21541 ctgtaaattc aggatacata tcaatatctc cagatttaag ggcttcatat aagaagctag
    21601 ttttcccaaa attagatttc aactcaacac ttatatctga ttggtcttca attaattcct
    21661 tatagagatt aatcagaata tcgggctctg ctcccaattt accggcaata accactgtat
    21721 cttttccttt tgaaaactga ctaagcgcca taggagtata cgatgctagc agtgcaagta
    21781 aggtaattcc aaaactaatc ataatccgtc gcaaggaagc tttctcaagg tactgtaaca
    21841 aactattgaa aataatagct agcagagctg aagaaatagc ccctatcaga atcaggttag
    21901 cattattacg atcaatccct aataagatga aagagccaag tccaccggct cctatcaagg
    21961 aagctaaagt agctgtgccg ataatcatga ctgctgacgt ccgcacacct gacataataa
    22021 caggcatggc aattggaatc tcaaatgttt tcaatcgctc ccatttggtc atcccaaaag
    22081 ctattcctgc ttccacgaga cttgggtcaa taccatttaa tcctgtgatg gtgttttgta
    22141 aaatcggaaa aatcgcatag ataactaaag ctgtcactgc aggcaacgtt ccaattccca
    22201 ttaaagggat gaaaagacca agcaaagcca gtgagggaat ggtttgaaaa acacctgtta
    22261 cctgtaacat aatgtctgac caacgtttgc tgcgactgag aagggctgct aaaggcacac
    22321 ctattagcaa ggcgatcata agagataaaa gggaaatttg caggtgttcc cccagagccg
    22381 ccagccattc attaaaacgg ttttggaaag ttacaaacaa actaggcatg ctcatcacct
    22441 ccaaataaat tgaccacaaa agcattagca gggtgggtct taatcatttc tgggcgatcc
    22501 agttgcacaa tttctccctc atttaaaata gctacgcggt ctcctaattt aatggcctca
    22561 tcaatatcat gtgtcacaaa tacaatcgtc atgtcaaatt ccttgtgaag actcaacatt
    22621 aactcttgca attgtttacg tgaaatagga tctaaggctg aaaatggttc atccatcaat
    22681 agaattttag gatgagaaat gatagcacgt acaataccaa tacgttgctg ttcacctccc
    22741 gataaatcac ttgggtaacg atcaagataa tctttagcag gtaggcccac cttatccaat
    22801 aattcttcag ttttttgtct aatttcttca gctgaccatt gcttcatctc agggataatc
    22861 gtaatatttt cagctactgt gagattgggg aaaagagcaa tttgctgcaa cacgtatcca
    22921 atagatagcc tcatctcacg taaatctaac tctttctgtg ggacgttatt cagtaaaata
    22981 tctccagagc ttggttcaat aaggcagtta atcattttta aaagtgtggt tttccccgat
    23041 ccgctggggc caaccagcac aaaaaattca cggtcattaa tttgaaaggt ctgctcttgc
    23101 aaaacctttg tctgaccaaa agttttagaa acattattaa aacgtatcat tatttctcca
    23161 attcattggt taaagtaaca gcataaaagc tgatgagttc attcaacctg tctctctgtc
    23221 attttttctc aaaacgttct gagtaactac aaggaatcac tgcatgccct accattttta
    23281 gacaaacgca tctactaatt aaagggactc ttaggtatcc tcagtaaggt aaaaactacc
    23341 aattctcaaa aacattttct ctcattattt tcttgtcgtt tgttgttgac cattataaaa
    23401 agtttcccac tataagtcaa ataatgagac tattaccccc ttatagaaaa acaggtcact
    23461 gggtcagcct atctctccaa aattacctta tcaaaaatcc tagacttgcc tatgatgata
    23521 gataagcaga ttaattgtct tttctagaaa atacagctat catacaatta tgaaaaatgc
    23581 catttccatt ttagcgctct taacacctga aaaccaactt gaagagacgt ttattagaga
    23641 gctttcccac cacttctcac acctttttga ggtgactatt ctcactagca aagccaacat
    23701 tcagtcaaat caattgtcga ctttccaagg aattttcagt ttccatgagc atgacattga
    23761 cttgcctaca ctctatttca aaacttctca acatggtcag ggctttttag tgacagaaag
    23821 tgtctttgat caagcaacag cagtcttatc gttaagccaa tacctcactg gattttacca
    23881 aaaatttgat ggacattttt tacagtacct tcctttgcaa gcaaggttat ctgatgcaaa
    23941 tggaaacatc atagtcgata atcatgcttt taatggaagt tttttgccaa ctactgataa
    24001 agaaatagaa gattggattc ttgctgaatt gcgtttatca gataaccctt gtaaaacctt
    24061 cctacttcct tcgggttcat tggatcatat ttacatgcag cattatcaag ctcttaaaaa
    24121 tcctcaaggt cagctggtgg gagttttgaa taccgttcaa gacattaaac cgttattaaa
    24181 ccagtattta gaagaaactg gacaagccat tgttggctgg tccgatgtca catcaggccc
    24241 ttccatttta gatcactaaa cttgatttta aatagggagt tcagcctaaa tcatcaacgc
    24301 acaagaagca atcatgaacg cttgaagacc ccaaaacctt cttcttgatt gctttttttg
    24361 atgactaaat cggtaagtct cacttataaa gaataatcca taccagtaaa ccatttttct
    24421 aaagattatt attcttatgg actcatccct tgctagtcac gactaactgg ttgcggtcca
    24481 taactttgcg acactggcat cagctcaata cgattaacat taacatgagg gggctgatga
    24541 atcacccatg atacagtcga cgcaatatct tgaggttgaa tggcatgtgc tccttgataa
    24601 atggccttca cccgtgcctc atcaccatta aagcgaacct ttgaaaattc tgtcccttca
    24661 catagaccgg gctcaatatt ggtcacacgt atatggctac ctgctaaatc agctcgtaaa
    24721 ttgagtgaga actgcttaac aaaagccttg ctagccccat aaatattagc tcccggatag
    24781 ggaattgtcc ctgcggttga ccctaaatta ataataatac catcatcttt ggagaccata
    24841 tgtggtaata attgacgtgt gagataaatc aacccaacaa tattagtgtt aatcatcgtc
    24901 atccaattct caaaatcggc ttcataagcc ttatcaagtc ccaatgccaa gcctgcatta
    24961 ttcactaaaa tagtaatatc ttgccactga tttggtagac ttgtcaaagc atcatcaatc
    25021 gctttggtat ctgtgacatc catctgcaaa gggtaaaagt tgtccgaccc aaagctcgtt
    25081 tctaaggcct tgagtttctc aagacgacga gaagcaccaa taacctttat cccatctgca
    25141 attaagtgtt cgacaatggc tctgccaaaa ccggctgaag cccctgttac taaggcaata
    25201 tttcccatac atttcctcac cttcaaaaaa aacgagatgg tctggccaac tcgtttttaa
    25261 taatgtcaat tagtcttagg acaacttcta acacatcact tagcggttag gatcctatat
    25321 caaggggtct taagttaccc ttggctttca atagcttgtg ctgctgtaat aatagctaat
    25381 ttgtaaatat cttcagcgct tgagccacga gataaatcat taacaggttt gttcaatcct
    25441 tgtaagattg gtccaatagc atcaaacatt cctaaacgtt gtgcaatttt gtaaccaata
    25501 tttccagatt gtaagtcagg gaaaataaaa gtattggctt ggccagcaac tgctgaatct
    25561 ggtgctttga tagctgctgt ttcaggaaca aaggctgcat caaattgcaa ctcaccatca
    25621 agtgccaaat cagggttcaa ccctttagca atttctgttg cttctcttac cttatcaact
    25681 tgaggcgctt taccagaacc ttttgttgag aagcttaaca tagcaatttt aggatcaata
    25741 tcaaagattt tagctgtttc agctgtgtta acagcgattt ctgccaattc ttgtgctgtt
    25801 gggtcaatat tgatagcaca atcagcaaac acgtaacgct cactcgtatt ttcgcgattc
    25861 atcaagaaaa cacctgaagt tcttgaaata cctggtttgg ttttaatgat ttgaagggct
    25921 ggacgaacag tatcagctgt tgaatgaata gcaccagata ccattccatc tgctaatccc
    25981 attttaacca acataacacc aaagtaattc acatcacgaa gcattttatc agcatcttca
    26041 agcgttgctt ttcctttacg gatgtcaaca aaagcttctt tcattttgtc aaaatccgca
    26101 tattcatttg gattaatgat agtatagtct tgatcagcga aacctaattt tgtcaaaagg
    26161 ttgcgtacct cttctgactg tccaaggata atcggttcta agagtccttc aaatttcaaa
    26221 cgagcagctg cacggacgac gcgctcatca ttaccttctg ggaaaacaat cttcatgttt
    26281 ttaccaagaa ttttttctct taaaccaccg aataaactac gaatactcat tctttaataa
    26341 cctctatctt ttttctgtaa acctatgata acgctatcaa agtcatctgt caagtgtatt
    26401 gcatagctac aatcactttc tgtaaatgga tctttgaaat tcaaataatg acaatgtaaa
    26461 gcttgccttg ttattcctaa gtccaaacga cctccgtaaa ggtcatcccc taaaagtgga
    26521 aaaccaatat gggcaaaatg aactctgatt tgatgggtac gtcctgtatg caatttgata
    26581 tccactaaat gcacattttc tgaatagcgc gccacaacct tatagctagt cttggcatat
    26641 ttgcccatag ggtcaactgc cctggtaata atactatctt ttgaacgccc aattggagca
    26701 ataatatctc cttcatctgg caacgtccca tttccagaaa ccagagcaaa ataacgtttc
    26761 tctattgagc gagtttggag ttgcttgtcc aaccttgcat gagcataacc atgcttagca
    26821 aataacatca agccactcgt atctctgtct aaacgagtca cgatatgcac ttgttggtct
    26881 aggtaatgat tgtccacata atatgccttg ataaagttag caatggtatt ggagtggatg
    26941 gcacttggaa tactggcaaa gccaatgggt ttattaatca ccaaaaaatg atcatcctcg
    27001 tgaacaatat ccaaatcaaa agggatggct tcaagctttt caaagggctc ttcgtttgga
    27061 atgtcaatgg tgacaacatc tcccacttgc aataaataaa tggcattttg ttcaatacca
    27121 ttcactaata tattaccgcc cttatatttg attttagcca atagtccttt agagacatca
    27181 tgacttttta aaagggtttt tacttttatt cgtttgtctg ctacaaattc aaatctcatg
    27241 agtcaatctc tccaataaag gcatccttga ccctttccca aaagctcgta tgactcggag
    27301 aggaaacaaa atgaattttc tcatcgtcga taaaatactc caccttcgtc acatttttta
    27361 actgataggt tttattatca atggaaatgg tataaattcc taatcgtttt ggcactaact
    27421 caatcttatc ttttttggga ataatgattg atgagcccaa ggttctaaag acacggttat
    27481 taagactgga aatttccgtc aattgcagcg cttcaatcgt cggatgcaag acagcaccac
    27541 ctaaagattt attgtaggct gtgctccctg tcggggtcga tactgaaatc ccatcacctc
    27601 ggaagctttc aaatttgaca tggttaataa taacatctgc taccatcgtt ttttcaatac
    27661 gcttaaccgt cgcttcattc aaagcacgcg ctttaaccac acgaccatca tctaaagtaa
    27721 tagcaacttt taaaatcgga taagagattt gttctccctt gtcttttctt aaattatcaa
    27781 tcaatttatc aacttcaaaa tccctataat cggtataaaa gccaagatga ccggtgtgga
    27841 ttcctacaaa acgtacctta tctaattctt tttcatacat gtgaaaggca gataagagca
    27901 tcccatctcc gccaatagaa atcacaatat ccggattttt ctttgaaaga tagaaatcag
    27961 gatcatcttt aaatacggag aaaagtttgg aggcgacgcg tttactttgg tacttaccat
    28021 ttgcaataat agcaactcgc tttaccttac ctgtataatt catctgtgtc atcactattt
    28081 cctacaccat cacttaaatt tcgtgtcacg gggtcaaaca ataattgagc ctcccggata
    28141 tcttctcgaa tcttacgcat ttcttcgtct aattctaaag caattttagc agtcacttca
    28201 agacgctttt taatttcttc tgggaagtct ccaccatatt tataatttaa agaatgctca
    28261 atggtcgccc aaaagttcat tgccaaagta cgaatctgaa tctccgctaa gacctttttt
    28321 tgaccttcaa tggtgtcaac agggtactca accaccacat gataagacct gtagccactg
    28381 gacttcatat tgcgaatata atctcgttca taaacaattg tcatgtcttg tcgttgacgc
    28441 aatagagcta agacttcttc cacatcatca acaaactgaa ccataatacg tagtccagca
    28501 atatcttgaa tatcttgtgc tatattttct tcaataacac cacgtaaaat cattttttct
    28561 ttaatacttt caattgactt aacacgtccc gtaacaaatt caatcggaga ataacgattt
    28621 tgcttacgat attgcttgcg aataccccgt agttttattt ttaattcacc aactgtttgg
    28681 atataaggat ctaaaaattc ttcccaatct aaggtcatct attgtctcct ttcttgtcaa
    28741 agccaggata ataatataaa attgaaataa caatttatta tagcacaaat taaaaggaat
    28801 ttcccatgac taacctagaa atcgaatata aaactctact tacaaaaaac gagtataacc
    28861 gtcttttatc tcaaatgaaa catgtgacgc ctgttacaca aactaattac tatattgata
    28921 caaaagcatt tgatttaaaa gctaacaaaa tgtcattacg tattcgaaca tttgcaaata
    28981 gcgccgaatt aaccttaaaa gtgccagaaa aagtggggaa tcgtgagtac aatgtccctc
    29041 tttttcttga acaagcaaaa gatatgatta aacatgggaa tcttcctgaa tcaactgctc
    29101 ttgatattat tatttcaaaa ggtatcaaac catctgcact ggtaactttt ggcaatttaa
    29161 ctaccgttcg tcgcgagaca gtgataccga taggtaaatt ggccttagac tataacctat
    29221 atgccaatac caaagactat gaattagaat tagaagtaag tgacgctctt caaggaaaga
    29281 ttgattttga ttctttttta tctgaacatc acattgcttt caaatatgct aaaagcaaag
    29341 tagctcggtg tattaatacc ttaaaaaagt tcaacgataa ataatggcta aaagcgacag
    29401 aaaaactgaa atttttctgt ttttctgtta aaatagggat gtcaattaaa cacttttggg
    29461 taatgtgact cattaataaa acagtttacc caattttatt gaagttaagg agctaaatct
    29521 atcatgactg aacgatatgc tgacaagcaa atcaaactgt tctcactcac atcaaatctt
    29581 ccaattgctg aaaaaattgc taaagctgct ggaatccctc ttggaaaaat gtcttcacgt
    29641 caattttccg atggagaaat tatgatcaat attgaagaaa cagtgcgtgg agatgatatc
    29701 tatattattc aatccactag ttttcctgtc aatgataatc tttgggaatt actcatcatg
    29761 attgatgctt gtaaacgtgc aagtgctaat accgtcaata ttgtattgcc atactttggt
    29821 tactctcgtc aagaccgtgt cgctaagccc cgcgaaccga ttactgctaa actagtagct
    29881 aatatgttga ctaaagctgg tattgatcgt gtagtgacgc ttgacttaca tgctgttcag
    29941 gtacaaggtt tttttgatat tccagtggat aacctcttta cagtccctct ttttgcagaa
    30001 cgttacagta aattaggctt atcaggttct gatgttgttg tcgttagccc taaaaattct
    30061 ggaattaaac gtgctagaag cttggctgaa tatcttgatt ccccgattgc tattatcgac
    30121 tatgcacaag atgattctga acgtgaacaa ggttatatta ttggtgatgt ttctggtaaa
    30181 aaagccattt taattgatga tattttaaat actgggaaaa cctttgcaga agctgctaaa
    30241 attcttgaac gctcaggcgc tactgatact tacgcggttg ctagccatgg cttatttgct
    30301 ggtggagctg ctgatgtatt agaaacagct ccaatcaaag aaattatcgt tacagattct
    30361 gttaaaacta aaaatcgtgt gccagaaaac gttacttatc ttagcgccag tgatttaatc
    30421 gcagaagcta ttattcgtat ccatgaaaga agacccttaa gtccgctttt ttcttatcaa
    30481 cctaaaggca aaaataacgc atgacttact ttgataacgc cgccaccaca ccacttagtc
    30541 ctaatgtgat tagggcgatg acagcagcta tgcaagataa ctttggtaac ccctctagta
    30601 ttcatttcta cgggcgccga gccaataaaa tccttcgtga atgccgacaa gctatcgcta
    30661 gaaacttggg ggcaagtgaa cagcaaatta tagtaacgtc cggtggaact gaaagcaata
    30721 atatggccat aaaaggctat gctttaactc atcaagcaaa gggcaaacat ctcatcacaa
    30781 ctactattga gcaccactct gtgcttcata ccatggccta tctcgaagag cgatttggtt
    30841 ttgaggtcac ttatttgcct tgtcaaaatg gacaaataaa tttatctgac ttaaaacaag
    30901 ccttgagaga tgacaccatt ttggtaagca taatgtatgc caataacgaa acaggtgacc
    30961 tgttacctat taaggacatt gggaatctgc tcaaagacca tcaagctgct tttcatgttg
    31021 atgccgttca agctgttggc aaactcaaga ttattcctag cgaacttggg attgactttt
    31081 tatctgcttc tgctcacaaa tttcatggtc ctaaaggatg cggcttttta tacagtaacg
    31141 gacaaccaat cgaccctctt cttcacgggg gtgatcaaga aggaaagcga cgcgcaagta
    31201 ctgaaaatat gttaggtatt attggtatgg cacaagcttt gactgatgct atgacttgtc
    31261 ttgaccaatc aactgatcac attatcagtt tacgtcatca cttgattagc ctcctagaag
    31321 gactacccta ctatattaat caaggtactc attatcttcc tcatgttctc aatattggat
    31381 ttttaggcta ccaaaatact attttactaa cacaacttga cttagcaggc attgcagtat
    31441 caactggttc tgcttgtact gctggagctg ttaatccaag tcatgtttta gctgcgtact
    31501 atggggatga ctcttctcgt ttaaaagaat caattcgtat cagtttttca gatcaaaata
    31561 gcattgaaga tgttaatcaa ttagctcaaa cattaaaaaa tattttagga ggaacagatg
    31621 gcttttgaaa aagaaattaa gcttaaagac tgtaaatacc tttatacaat cagtccaaac
    31681 attaaaaaat ataccctaag agatactaca tttagtcaaa ctaaagtagg gcactaccaa
    31741 ttaatacgtt tactcgaaaa aatacctaat tcaggggatg gtttcccttt aaaaatcact
    31801 attaataaag aactcacagg ttttaaatta gctatc
//
LOCUS       DAUGSW010000017        29530 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUGSW010000017 DAUGSW010000000
VERSION     DAUGSW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29530
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.017"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            27..353
                     /gene="gpsB"
                     /locus_tag="VIB18_000948"
     CDS             27..353
                     /gene="gpsB"
                     /locus_tag="VIB18_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEQ8765966.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            367..735
                     /gene="rnpB"
                     /locus_tag="VIB18_000949"
     ncRNA           367..735
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VIB18_000949"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            799..1953
                     /locus_tag="VIB18_000950"
     CDS             799..1953
                     /locus_tag="VIB18_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEQ8765967.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVEKGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKINGVVISNPPYGERLLDDKAVGILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            1967..3436
                     /locus_tag="VIB18_000951"
     CDS             1967..3436
                     /locus_tag="VIB18_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765968.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQITKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAVLKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(3581..4063)
                     /locus_tag="VIB18_000952"
     CDS             complement(3581..4063)
                     /locus_tag="VIB18_000952"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEQ8765969.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(4137..5468)
                     /locus_tag="VIB18_000953"
     CDS             complement(4137..5468)
                     /locus_tag="VIB18_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEQ8765970.1"
                     /translation="MEIIGSLGVLVGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIVIAFDLFS"
     gene            complement(5539..6318)
                     /locus_tag="VIB18_000954"
     CDS             complement(5539..6318)
                     /locus_tag="VIB18_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEQ8765971.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            complement(6351..7010)
                     /locus_tag="VIB18_000955"
     CDS             complement(6351..7010)
                     /locus_tag="VIB18_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8765972.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            complement(7012..7662)
                     /locus_tag="VIB18_000956"
     CDS             complement(7012..7662)
                     /locus_tag="VIB18_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8765973.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADVALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            complement(7686..8873)
                     /locus_tag="VIB18_000957"
     CDS             complement(7686..8873)
                     /locus_tag="VIB18_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8765974.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVSRQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGIENMSQAAYVSTQHRFGQHLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAARALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            9074..9970
                     /locus_tag="VIB18_000958"
     CDS             9074..9970
                     /locus_tag="VIB18_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8765975.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            10100..11707
                     /locus_tag="VIB18_000959"
     CDS             10100..11707
                     /locus_tag="VIB18_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEQ8765976.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            11817..12452
                     /gene="gmk"
                     /locus_tag="VIB18_000960"
     CDS             11817..12452
                     /gene="gmk"
                     /locus_tag="VIB18_000960"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEQ8765977.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            12468..12785
                     /locus_tag="VIB18_000961"
     CDS             12468..12785
                     /locus_tag="VIB18_000961"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEQ8765978.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            12850..15234
                     /locus_tag="VIB18_000962"
     CDS             12850..15234
                     /locus_tag="VIB18_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEQ8765979.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFIIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKSDRDFLFEGKPSVLYSTLDREKEKIALKAIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERPIDRSESYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEAKILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            15296..16231
                     /locus_tag="VIB18_000963"
     CDS             15296..16231
                     /locus_tag="VIB18_000963"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEQ8765980.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMELGADGIITAAFGQFLPTLLLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            16221..17543
                     /gene="rsmB"
                     /locus_tag="VIB18_000964"
     CDS             16221..17543
                     /gene="rsmB"
                     /locus_tag="VIB18_000964"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEQ8765981.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLIYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRAVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            17581..18321
                     /locus_tag="VIB18_000965"
     CDS             17581..18321
                     /locus_tag="VIB18_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEQ8765982.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            18318..20216
                     /gene="pknB"
                     /locus_tag="VIB18_000966"
     CDS             18318..20216
                     /gene="pknB"
                     /locus_tag="VIB18_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEQ8765983.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIIFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            20339..21031
                     /locus_tag="VIB18_000967"
     CDS             20339..21031
                     /locus_tag="VIB18_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEQ8765984.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            21028..22032
                     /locus_tag="VIB18_000968"
     CDS             21028..22032
                     /locus_tag="VIB18_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8765985.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            22025..22666
                     /locus_tag="VIB18_000969"
     CDS             22025..22666
                     /locus_tag="VIB18_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8765986.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            22703..24103
                     /locus_tag="VIB18_000970"
     CDS             22703..24103
                     /locus_tag="VIB18_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEQ8765987.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            24103..24480
                     /locus_tag="VIB18_000971"
     CDS             24103..24480
                     /locus_tag="VIB18_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8765988.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(24498..25439)
                     /gene="cysK"
                     /locus_tag="VIB18_000972"
     CDS             complement(24498..25439)
                     /gene="cysK"
                     /locus_tag="VIB18_000972"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEQ8765989.1"
                     /translation="MTKIYKTITELVGQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(25567..26199)
                     /locus_tag="VIB18_000973"
     CDS             complement(25567..26199)
                     /locus_tag="VIB18_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEQ8765990.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNRQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIELPCD"
     gene            26255..27580
                     /locus_tag="VIB18_000974"
     CDS             26255..27580
                     /locus_tag="VIB18_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8765991.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            27552..28217
                     /locus_tag="VIB18_000975"
     CDS             27552..28217
                     /locus_tag="VIB18_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEQ8765992.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            28297..28845
                     /gene="raiA"
                     /locus_tag="VIB18_000976"
     CDS             28297..28845
                     /gene="raiA"
                     /locus_tag="VIB18_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEQ8765993.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
BASE COUNT         9574 a         5244 c         5998 g         8714 t
ORIGIN      
        1 aagattgacc gttcggagag taaagaatga caagtattat ttatagtcct aaagatattt
       61 ttgagcaaga atttaagact agtatgcgag ggtttgataa gaaagaagtt gatgaatttc
      121 ttgataatgt aattaaagat tatgaaaatt tcaatgctca aattgaagct ttaaaagctg
      181 agaacgaagc cttaaaaaag gcgaagtttc aagctagaaa tacagtttca gcgactgttc
      241 aacaaccagt accgcaaccg actcgtgttg ctcaatcagc tactaatttt gacatcttga
      301 aacgtattag taaattggaa aaagaggttt ttggtaaaca aattattgag taatgaaaac
      361 tgtgcaattt ttggataatc gcgtagtatt ttaatactat gaggaaagtc catgctagca
      421 ctggctgtga tgccagtagt gattgtgcta ggcgaacaca taagcctagg gatgtatata
      481 cacattacgg cgaaggaaat ggctaagtcg tttgatatgc caaagtactt ctgaaagtgc
      541 cacagtgacg tagtttttat ggaaacgtaa aaaatggaac gcggtaaacc cctcaagcta
      601 gcaacccaaa ctttggtagg ggcatgggat agttggaaac gaacaagcta tcctgactgt
      661 caacagacgg tagacagatg attatcgaag gaaataattc ctagttattt ccggaacaaa
      721 acatggctta tagaaaattg cataataggt taagctagca cttgctagct tttatttgat
      781 ttaaaagaaa gagatagtat gaaagaaaca tttagattag tcgcaactgc agccgcaggt
      841 ttagaagctg tcgttggtaa agaagtcaga gcactaggct ttgattgtca ggttgaaaag
      901 gggaaagttt attttgaagg tgatgtagaa gcgattgtta aaacaaatct ttggttacgt
      961 gcagcagatc gtatcaaaat tatcgtagga caatttcctg ctagaacctt tgaagaatta
     1021 ttccaaggtg tctttgcctt ggattgggaa aattatttac cgctaggagc taaatttcca
     1081 atctcaaaag ccaaatgtgt taagtctaaa ttgcataacg agccaagtgt tcaggcgatt
     1141 accaaaaagg ccgttgttaa gaaactgcaa aagcatttcc acaggccaga aggagttcct
     1201 cttcaagaag ttgggtcaac gtttaacatt gaggtatcta ttttaaaaga ccaagccact
     1261 attatgattg acacgacagg atctagccta tttaaacgag ggtaccgcgt tcaaaaaggt
     1321 ggagcaccga tcaaggaaaa tatggcagct gctatcttgg ccttatctaa ctggtttcca
     1381 gataaacctc tggttgatcc cacctgtgga tcgggaacgt tttgcatcga ggcagccctg
     1441 attgggatga atattgctcc aggatttaac cgttcgtttg cttttgaaga atggagctgg
     1501 gtagataaag acatggtgca acaagttcgt gatgatgctg aacaagaagc taattatgaa
     1561 atcgaattag atatttctgg ctttgatatc gatggccgca tgattgagat tgctaaaagt
     1621 aatgctgaag aagctggttt atctgatgtg attaccttta agcaaatgcg tctgcaagac
     1681 tttcgaacag acaagattaa tggtgtagtg atatcaaatc ctccttatgg agaacggttg
     1741 cttgatgaca aagcggttgg catcttgtat aatgaaatgg gacaaacctt tgcaccattg
     1801 aaaacatgga gcaaatttat ccttacaagt gatgaacttt ttgaactaaa atacggtcaa
     1861 aaagctgata aaaaacgtaa actttataac ggcaccctaa aagttgattt gtaccaattt
     1921 tatggggaaa gggtaaagcg acatctgata tagagaggta gtaagcgtgt cagaagaaag
     1981 caaagaagtc gaagtaacaa aagaatcgca aacattgggg cttaatgaag ccaagtcaat
     2041 gacaattggt gaagctgtac gcaaacagtc agagataaaa gcaggtgtta ctaaggatga
     2101 tagtatttta gataagtaca ttaagcaaca ccgtgacgaa gtttcttctc aaaagtttga
     2161 tgctaagtat acagagcttg atacagctag tttagataac tttatcaaaa aacaaagaga
     2221 agcattgagt aaagccggtc ttgttgatga cgaacctgtg tctgcggagt ctgctgagca
     2281 agatagcact ttggttgaag aagtagctga agacttagct ccaatggaga ctactgcggt
     2341 ggtaactggg attccggtgg aagcgacagt ccctgtgtta gatctagatc catcagagag
     2401 agtcattccg gaaccacaga taaccaaaga agagccaaaa agagatcagt ttctttctga
     2461 agatagccac catccagcca aacaaaatac gaaaaaaggt tggttaatag ctttatttct
     2521 gctattattg gccattcttg cagttgtatt tggttggaac catttcttga gacaagacag
     2581 tggtaaaaca actcaaacag caagtaaaca gacaaagacc tctttgcaga ccgacagtgc
     2641 taaaaaagca acgcgcttga aggctgctgc taaagctttc gaaaaacaat atggtacttt
     2701 ttatacagat gccacaaaga gcaaattaaa aaatagtgcc tttgctactt tgccagattt
     2761 agaagctgtc ttgaaagctt tggaaggctc tgcttactat gataaggcga aagcaaaagt
     2821 cgattccctt aagaaagcta ttgctgctat tacagcggtt aacggtaaat ttgtttccga
     2881 tgttgttgta gatggtgaaa aggtttcggc tgaagtcaag gctgatgcta attttgatga
     2941 tttatcaagt gcaaccttga caacaggaaa tgcaaatctt gatgctgtct tgcaggcaag
     3001 catcacagaa ggtcgtcagc aactagccag caaggctgag gccgctaaag cagctaatga
     3061 gcaagcagcc caggctcaag cagctcaagg acaaagtaca tcagtagcac catctggcta
     3121 tggcttgaca agttatgacc ctgcaagctt acaacggcat ttatcacgtg taccttacaa
     3181 tcaagatgtt attgctgaca gagctaaccc atcttgggca tttaatccag gagttcttga
     3241 aaaaattgta gcaacctcac aagctagagg ttatatttca ggcaaccaat atattttaga
     3301 accggttaat attattaatg gcaatggtta ctataatatg tttaagcctg atggcactta
     3361 tctgttctct attaattgta agacgggtta ttttgtagga aatggcaaag gttatgctga
     3421 tgctttagat tactgagaaa atcaaaaaaa ctgagataag gcaacttgtc tcagtttttt
     3481 gattaataaa gtatgttgtc ttaaaatctg cagatagact tgttttttgt aacaagtcaa
     3541 ataggtcagt aggattgtta tgtttgacaa cacactagta tcagatgaca tggcgactaa
     3601 aaggatcgtc tgaaatccct tgatcaataa tcaattgagc ccattctttg gcggcaaaga
     3661 ggctatgatc cttatagttc ccacaggatt caagagttgt tccaggaaca tcttcccaag
     3721 taatcccagt tgcaatttct tctaggctgg atttaatcac cttggcaata tcagtagaac
     3781 tgtgttttcc ccacatgata aggtgaaaac ctgttcgaca gccaaaagga gagcaatcaa
     3841 tcatcccatc aatgcgttgg cggatgagct tggcaagtaa gtgttcaatg gtatgcaaac
     3901 cggctgtttc aatagaattt tggttaggct gcactaggcg aacatcaaaa tttgtaatac
     3961 gatcgccctt gggtccaaat tcttcagaaa taagacgaac ataaggggcc tttacaatag
     4021 tatgatctag ctcaaaactt tcgacgataa cttcttttgt catttcaatc tcctttgttt
     4081 tacactttat cataacacaa atagtgagaa agtggctact tgtggaggag aaaaggctaa
     4141 gaaaacagat caaaggctat cacaatgacc tgtgcgataa aagtacttac agaaacagta
     4201 ataaaggttt ctttaaaagc atttttgtgg ttaagtcctg tcaatgctaa gaaggtgaga
     4261 aagacaccac tttggggcac aatggtaaag atattcgaag caatagtggc aacacggtga
     4321 atcatttcgg gattaaggcc ttgatctaaa taatactggg caaaattagg catgacaatt
     4381 cctagagcac ctgaagaaga accggtaata gctgacatag aggaagtcaa cacggctaaa
     4441 ctaataagag gattaccggg aatattcaaa atgagatctg agaagaatgt gaaacctggg
     4501 gcaatcatca caacggctcc gaaggcaact gcagatgctg tcgcaaaaat aggtgcaata
     4561 gagctgctag ctcctaaatt aaagacagca atcttattag gaataaactg tctaaagagc
     4621 cagcttgcgg tgagaatggc agctaaaagt gctatgaaaa taatgttctt cttaaaaaaa
     4681 tcgtttccga aaaggctacc ggttagggcg ataataatga gcaacaataa aggtaagata
     4741 ctggcaagga aatgtgggag attttttgtt ttcacttgta tctcattgtc aaaagcataa
     4801 gtggcataag tttcacccct tgccatactt tttgctagac aatatttcat ataaaagagc
     4861 ccaaaagtca cgcagccaat tgagccaacg atactcggaa tggcggcagc agttagtgag
     4921 gtgtccaagt attgaatagg aataacattt tgaatggcag gtgttccggg taaaatcgtc
     4981 atggtaaaag ttgcaatacc gagccaaaga ggaacttgaa ttaagttcca agccaagtcc
     5041 atttttttga atagacttcg tgcaagcggc aagacagcaa acatgacaac aaagaggctg
     5101 attcccccat aagttaatat agcactgatc agaaaaatag caacgagtac tttataagga
     5161 ctatcatgac caactttttt taaaatataa tctgcaatag aagtggttgc accgcttgtt
     5221 tccattaatt tggctaagat agaacctaat aaaaagatag caaaataatt gagaatataa
     5281 gtggagagtg cccccataaa ttggttgggt tcttttccaa gtaaggttgt ggttggatcc
     5341 atttgattaa acaaaatgac caagctggta gcaagaggcg cagcgatgat aatgttaact
     5401 tctttgacag acaggtaaat aataacaata acacctacca agacccccag agaaccaata
     5461 atttccatag ttttatgacc tccttattag aaaataaaga gacagatcac aagatacagc
     5521 ctctttatct ctccaaattt attgagcagt gtagccaccg tctaagatac aggcttgacc
     5581 tgtaacacct tttgccttat cactggcaag gaaagacaca tagtctgcaa tttcttgaac
     5641 gtcaatgagg cgtttttgag gaacaagtgg gtatagcact tcttcaagaa cattttcaag
     5701 gggaatacct cttgttttgg aaaggtcttc aaactggcca cgaaccagtg gtgtgtcaac
     5761 atatccagga caaatggcat tgaccgtaat gcctgaatca gcagcttcta aggcagttac
     5821 tttggtcaga ccgatcaagc cgtgcttagc tgaattgtag gcggatttgc cagcaaaacc
     5881 aatgacacca ttgatagaag ccatattaat aatacgaccg tgtttttgag ctttcattgt
     5941 aggaaaagca cgtttaatgg caataaatgg tgctgtcaac atgattttaa tcatgaattc
     6001 aaatttttca gttggaaaat cttcaatcat ggcaacatgt tgaaggcctg cgttgttaac
     6061 caaaatatca atacgaccat atttttcaac aaccgtatca atagcagcat tgatggcttc
     6121 ttctttggtg acatcgcaca caacactaaa agcgtcatag ccttctttag tatagtcagc
     6181 aacaacctga tccagttttt cttgattaat gtcagaaaaa acaaccgttt taccttcttt
     6241 taataaggtt tccccgattt gttttccaat tccgcttgca gcaccagtga taaatgcaac
     6301 ttctttagta tgtgtcatga tactatcctc gtctttcttt tggttagtct ttagtttgtt
     6361 ttatcaatta gggtaacttc ggtaacgttt tgcacgtctt caaaggtgta atctgggtta
     6421 atttcaaggg cgcatagacc ttcatcttga tattcaaaga ctcccatttc agtaatgatt
     6481 aggttaacaa cattttgagc agtcagagga agggtgcatt tgtctaaaat ttttgctttg
     6541 cctttattgg tatgctccat tgcaacaatg acttttttag cacctaccaa taagtccatg
     6601 gcccctccca tcccaggaac catttttcca ggaatcaggt aattagcaat gctagcttct
     6661 ttatcaactt gtaaggcacc taagacggtt gcggccacat ggccgcctcg aataatacca
     6721 aaggaagttg agctatcgaa gaaagcccct ccaggagcaa tactaacagg ttgcccacca
     6781 gcattaacaa tagtaggatc gtagtgatca tctgttaatc cagtgagacc gacaaaacca
     6841 ttttcggact gcagggtaat ggttacacct tcaggaatat agttggctac ttttgttggc
     6901 aaacctatgc ctaagttgac cagtgtattg tgttctaatt cttgtgcaac gcgcttagca
     6961 atacgtgttt gaatctcttc ttttgaaaga acagtagctg atgttcccat gttaggctcc
     7021 tttcactaag tagttaacaa aaatgccagg agtatggaca aaattaggat ccatttgccc
     7081 cacgtcaaca atttctcttg cttcaacaat ggtggttttc gcattagcag ccatcacatg
     7141 attaaagtta ttttcagaac ctgcgtattg caaattgcca tttttatctg ccttgttagc
     7201 aaaaataagt gcgacatcag ctttcaaagg tttttcaaga aggtagtctt tgccgtcaat
     7261 agtaatgact tcttttcctt tggcaacttc ggttcctatt ccagtaggtg ttaagaaacc
     7321 gcctagccca aaaccgccac tgcggatgcg ctcagctaat gttccctgag gtacaagatc
     7381 aattacagtc tcgccctcag tcatttgtcg gcccgcttca cggttgagac cgatatgtga
     7441 tgcaataata gttgaaaact gtttattggc aaccatctta ccaacgcctt tgtcaggaaa
     7501 accggcatcg ttacagatta aagtgaggtc tttgacacct ttttccacaa gtgcatcaat
     7561 taatttttct ggtgtgccat ttgtcatgaa gccaccaacc ataatggtat caccatcttt
     7621 aacgtgagct accgcttctt ttattgtgat ttctttacac attttttcta ccaactttca
     7681 cgagactaag tattgttttt cacgataaca gcagttcctt gtcctccacc aatgcaaagt
     7741 gttgctagtc ctctggttac ttggcgtttt ttcatttcgt ggattaatgt gactagaatg
     7801 cgagcgccac tggcaccaat aggatgacct aaagcgatgg ctcctccatt aacattcacg
     7861 atttctgggt ttaactttaa atcttttaaa accgccaagg actgtgctgc aaatgcttca
     7921 ttggactcca ctaagtccaa atcagaaatt gttaatccag ctttcttaag ggctttttga
     7981 gtggcaggaa ttggtccagt tcccatcagt tcaggtgcaa cacctgcact agcatagctt
     8041 tcaatagtga ctaaaggtgt taaccctaat tcaagagctt tttcttcagt cattaacatc
     8101 aataaggctg caccatcgtt tattcctgag gcattcccag cagtaacggt tccttcttta
     8161 gggaggaaag caggacgtaa ttgctgtaat ttttcaaggc ttgtgtcaac ttttgggtat
     8221 tcatccgtcg taacaattaa aggatctttg cgtcgttgag gcacagagac agggacaatt
     8281 tcgtcagcaa aacgatgatt ttctaatgcc ctagcagctt tttcttggct ttctaaagca
     8341 aattgatctt gctcttctct tgagatgcca tatttctgag caacgttttc agcagtaata
     8401 cccatgtggt aattgttaaa agcatctgtt aagccatcat gaacaagagt atcaatcaat
     8461 tgactattac caagatgttg accaaagcgg tgctgagttg agacataagc tgcttgtgac
     8521 atgttttcga taccaccagc aataacgata tcagcgtcac caagcatgat gctttgcgca
     8581 gctaactgga ttgctttaag tccagaaccg caaaccatat ctaatgtgaa agctgtttta
     8641 tcttcaggaa ttcctgagtg gactgcaact tgtcttgaca cattttgtcc taggcctgca
     8701 tgaaggacgt ttcctaggat gacttcatca accatttcag gctttacttg cgttttatca
     8761 aggatttttt tcagtacagt tgttccaagt tcaacagcag agacactttt aaaggagcct
     8821 ccaaaagctc cgataggagt tcgtaaagct tcaacgataa ctatgttttt cataaaataa
     8881 acatcctttc agttctagaa agcgctttct atgtctctaa gataacaaga aaacgctaaa
     8941 aataaaaata tagaattttt ataagcatat aaattttttt gatagagttg gcaatagcat
     9001 ttaacatcta cttgtgtcat aatataggta attataccgg aaaaagcaat tgataagaca
     9061 aggagaatcc tatttggata ttaaacaaat tcgttatttt atcgcaatcg ttgaaaatca
     9121 ttttaacttg agccaggcgg cggaactgtt gtatgtgtcg cagccgacac ttagcatgat
     9181 gatcaatgat tttgaaaaaa gggaaaatgt taagctcttc aaacgaaaaa gaggtcgtat
     9241 tattgggtta acctatcttg gtgataatta ttataaggac gctcaaaagg ttctcagtct
     9301 ctatgatgac atgtttttga aattgcatga tcacagtaaa gggttaaagg gaagtatcaa
     9361 tattggtatt cctcctctta ttttatcagt tgttttctca gaagtaatgc caaaactgat
     9421 tttagaaaat ccggggattc aattcaatgt taaggagatt ggtgcttacc aactaaaaaa
     9481 tgaactactc gtgggaaatg ttgacgtcgc agtcttgtta tccccaacag gcatcgctga
     9541 taatttggtt gagacttatg aaatccagag atcagaatta tctgtatgcc tgtctccacg
     9601 ccatcgttta gcttccaaaa aagttattca gtgggaagat ttaacagatg aacaacttgc
     9661 cctatttgat cctagtttca tggttcacca tttagtgctt gaagcttgcg agcgtcacca
     9721 agtcagacct aatattattt tgacgtcctc ttcctgggat tttatgctta attctaccaa
     9781 gattaatcac aacgtcttaa ctatttgtcc caaacctatt acagaattat accaattaaa
     9841 ggacattaag tgtattccaa tggaacgtcc catttcttgg cgtgttgtct taacacgcct
     9901 ccggaaaaaa agttattctg aaatagaagc ctacatcatg gacgacttgc tacagtcttt
     9961 ttttaagtag ggttctcaac cacttggtcc aaatgttaat ttttttaaaa atgaattgga
    10021 attgtgtaaa cgctcaattt atgataaact aagagatggc tttctattaa tgaaatctag
    10081 aatatattga ggtacaaaca tggttaatat tattttatta attgtttctg ccctcattgg
    10141 tttaatatta ggttatgcac ttatttcgat tagactcaag tctgcgaagg aagctgcaga
    10201 gttgactctt ttaaacgctg aacaagaagc tgttgatatt cgtggcaaag cagaagtaga
    10261 tgctgaacac atcaaaaaaa cagctaaacg tgaaagtaaa gcaaatcgta aagaattact
    10321 tttagaagca aaagaagagg caagaaaata tcgtgaagag attgaacaag aatttaagtc
    10381 tgaaagacaa gagcttaaac aactcgagac acgcttagcg gagcgctcct taactcttga
    10441 ccgtaaagat gaaaacctat caagtaaaga aaaggtacta gatagtaaag aacaaagtct
    10501 gaccgataaa tctaaacaca ttgatgagcg gcaacttcaa gtggaaaaac ttgaagagga
    10561 gaaaaaagca gaactggaaa aagttgctgc gatgacgatt gcagaagcgc gtgaagtgat
    10621 tttaatggag acggaaaaca aactgaccca tgaaattgcg acgcgcattc gagatgccga
    10681 acgtgacatc aaggaccgaa cagttaaaac agccaaggac ttgttagcgc aagccatgca
    10741 acgccttgct ggtgagtatg tgactgaaca aactattacc agtgtccatc tcccagacga
    10801 caacatgaag ggccgaatta ttggacgtga aggccgtaat attcgtactt tagagagctt
    10861 gactggcatt gacgttatta ttgacgatac tcctgaagtt gttatcttgt caggatttga
    10921 tcctattcga cgtgaaattg ctcgtatgac cttggaatct ctgattgctg atggtcgcat
    10981 ccatccagct cgtatcgagg aattggttga gaaaaatcgt cttgaaatgg ataatcgtat
    11041 tcgtgagtac ggtgaagctg cagcctatga gattggtgca ccaaaccttc atcctgattt
    11101 gattaaaatc atgggacgcc tgcaattccg tacctcgttt ggtcaaaatg tcctacgtca
    11161 ctctgttgag gttggtaagt tagctggtat tttagctggt gagttaggtg aaaatgttgc
    11221 tcttgcccgc cgtgctggtt tcttgcatga tatgggtaaa gctattgacc gtgaggttga
    11281 aggtagtcac gttgagattg gaatggaatt tgcacgtaaa tacaaagaac atccagttgt
    11341 tgtcaacact attgctagcc accacggaga tgtggagcca gattctgtga tcgctgtgct
    11401 agtagctgca gcagacgctc tcagttcggc tcgtccaggc gctcgtaatg agtcaatgga
    11461 gaattacatc aagcgtcttc gtgatttaga agaaatcgcg acaagttttg atggggtaca
    11521 aaatagtttt gctctacaag ctggacgtga gattcgtatt atggttcaac ctgaaaaaat
    11581 ttcagatgat caggttgtca ttttgtcgca taaagtaaga gaaaaaattg aaaacaatct
    11641 agattaccca ggaaatatta aagtaactgt tattcgtgag atgagagcgg ttgattatgc
    11701 caagtagaaa aagaggaatt atcctctttt tctttatgac ttgcctttga aaatgttctt
    11761 gaaaaagact agcctttttg ataaactatt aaaaagcaac taataaggag aatacaatgt
    11821 ctgaacgcgg tttgttaatc gtcttttctg gcccttcagg tgtcggaaaa ggaacggtaa
    11881 gacaagaaat tttttcaacg ccagatcata aatttgaata ttcggtttca atgacgactc
    11941 gtccgcaaag accgggcgag gttgatgggg ttgattattt cttccgcaca cgtgaagaat
    12001 ttgaagaact cattaaaact ggtcaaatgc tagagtatgc tgaatatgtt ggtaattact
    12061 atggcacccc tttaacttat gttaatgaga ctcttgataa gggaattgat gtctttttag
    12121 aaattgaagt tcaaggagct cttcaggtta agtcaaaagt accagatggt gtttttgttt
    12181 ttttaacacc accagattta gatgaattag aagaccgcct ggttggtcgt ggtacagata
    12241 gtcaagaagt catagctcaa cgtattgaaa gagcaaaaga agaaattgcc cttatgcgcg
    12301 aatacgatta tgcagttgtt aatgatgaag ttgccttggc agctgagcgg gttaagcgta
    12361 tcattgagac agaacacttt cgtgtggagc gcgtgattgg tcgttatgat aaaatgatta
    12421 aaataacaaa aaatcccttt aaagctaaat agaaaagagt aagcattatg atgttaaaac
    12481 cttccattga taccttatta gataaagtac catccaagta ttcacttgtg attttacaag
    12541 ccaaacgtgc ccatgaacta gaagctggtg ccactccaac tcaagaattt aaatcagtga
    12601 agtcaacact tcaggcactt gaagaaattg aatcaggaaa cgttgtgatt cacccagatc
    12661 cttcagctaa acgtgaagct gtccgtgcta agattgaggc agaacgcttg gccaaagagg
    12721 aagaggaacg taaaatcaaa gaacaaattg ccaaagaaaa agaagaagaa ggagaaaaaa
    12781 tctaaggttt cagaaatctt agattttttc atatttagta cgatgtccat gacagaaaag
    12841 gagaagcaaa tggaaaaagt agctcatgtg attgtagata ttccattgat gcaaacggac
    12901 aagccatttt cttatggtat tccaaaagag ttagtttctc tcgtgcagct tggttctcgt
    12961 gtgcatgttc cttttggaaa agggaatcgt ttgttgcaag gctttattat tggttttggc
    13021 caagaagatt caagctctct taaactgatt cagaccgttt tagatcctga gccagtccta
    13081 aaccaagaac aattgaccct tgctgatcag cttcgaaaaa cagttttttc ttataaaatc
    13141 acgctcttaa aagcaatgat tcctaatctt cttaactcta actatgataa agtgctaagg
    13201 ccagagtcag gtctaaaaaa gtctgatagg gactttcttt ttgaaggaaa accatctgtc
    13261 ttatattcta ccttagaccg cgagaaggaa aaaatagctc ttaaggccat acaagctggg
    13321 catattactg ttagttattt agccaaagac aagaaaaacc taaagacaga aaaatattat
    13381 cacgtcgact tagacgcctt agcggtacat cccatctcta gtcgtgccaa aaagcgtcaa
    13441 ttattaaaag actatctgct aacccatacg aaggaagcta aacttgcaac gctttatcaa
    13501 gccttttctc gagatgtggt ggcttacttt gtgacaaatc acttaattcg tattgacgaa
    13561 cgtccaattg atcgcagtga gtcctatttt gaccagatca aaccatcttc ttttttaacc
    13621 ttaaatgaac agcaggcgtc agctgttact gaaattgttg aacaaattgg gaaaccgagt
    13681 aaaccttttt tgattgaagg gattacaggt tcgggtaaga cagaagttta tcttcatatc
    13741 atcgaagcgg ttttaaaaca ggataagaca gccattgttt tagtgccaga aatttcgttg
    13801 actcctcaga tgacctctcg ttttatttcc cgtttcggaa agcaagtggc tattatgcat
    13861 tcaggcttat cagatggtga aaagtttgat gagtggcgca agataaaaac aggacaggct
    13921 aaggttgtgg ttggtgcccg ctctgctatt ttctctccac tagagcggat tggtgcaatt
    13981 attatcgatg aggagcatga atcaacctat aaacaagaaa gcaaccctag ataccatgcc
    14041 agagaggttg ccctgctcag agctaaacac catcaagcag ttgtggttat gggctctgct
    14101 acgccaagta ttgaaagccg agcaagggct agtaaggggg tctatcattt tattcaatta
    14161 acgcaaagag caaaccctct tgctaagatt ccagaagtaa cgattgttga ttttcgtgat
    14221 tatattggac agcaagcagt tagtaatttt accccatatt tgattgataa gattaaagaa
    14281 cgtttggtta aaaaagaaca agttgtctta atgttaaata gacgtggtta ttctagtttt
    14341 gtgatgtgtc gggactgtgg ttatgtggac aaatgtccca actgtgatat ctctttaacc
    14401 cttcacatgg atactaaaac tatgaattgc cattactgtg ggtttcaaaa acctatccca
    14461 attacttgtc ctgagtgtca tagcaatagt atccgctatt atggcactgg aactcaaaaa
    14521 gcttttgatg aattgcaagg ggttattcca gaagctaaga tcttgagaat ggatgttgac
    14581 actacacgaa aaaaaagaag tcacaaaacc atactagata gttttggtcg ccaggaagca
    14641 gatattttgt tagggacgca aatgattgcc aaaggactgg attttccaaa tgtgacttta
    14701 gttggggtac taaatgcaga tacctcctta aatttgccag attttcgagc gtcagaaaaa
    14761 acgtttcaat tgttaacaca agttgctggt cgggcaggcc gtgcccataa gccaggggaa
    14821 gtcttgattc aaacttataa tcccgatcac tatgctattc aattagctaa gaaacaagat
    14881 tttgaagcct tttaccgtta tgaaatggcg attcgccgtc agatggctta tcccccttac
    14941 tactttacag tgggtattac gctttcgcat cgtttagaag catcggttgt aaaaaaagct
    15001 tatcaagtta cagaactgct aaagagtcac ttatcggata atattaaaat attaggaccg
    15061 actcctaagc caattgctag aacacacaat ttataccact atcaaatttt gttaaaatac
    15121 cgttttgaag ataacctaga agagacgctc aatcgtattc ttgattggag tcaagaagca
    15181 gataatcgtc atttaaaact aattattgat tgtgaaccgc aacaattttt ataaggtaaa
    15241 tcactaaatc taggatgatc agttatgata taataaaaat acaaagagga aagtcatgat
    15301 aaaattatta tttatgggaa ctccccaatt ttcagcaact gtattgaagg gcttgctaga
    15361 taatcctgcc tatgagattt taggagtggt tactcagcct gatcgagctg ttggacgcaa
    15421 aaaagatatt aaggtaacac ctgtaaagca attagctctt gagcatggaa tatcaatcta
    15481 tcagccggaa aaattatcag gctctcaaga actcattgag attatggaac ttggtgcaga
    15541 tggtattatt acagcagcat ttggccaatt tttaccaaca ctattacttg attcagtttc
    15601 atttgctatt aatgtacatg catcattgtt acctaaatat cgaggtggag cacctatcca
    15661 ttatgctatt atgaatggag ataaagaggc tggcgttact attatggaaa tgattaaaga
    15721 aatggatgca ggtgacatgg tcgctaaagc aagcactcca attcttgaaa ccgataatgt
    15781 aggtactctt tttgagaaat tagccatcat tggtcgagac ttacttttgg atagtttgcc
    15841 agcttatctt tctggagaat taaaacctat tcctcaagat cacagccaag ctactttttc
    15901 acctaatatc tctccagaac aagaaaaatt agattggaca atgtctaatc aagaagtgtt
    15961 caatcatatt cgaggtatga acccttggcc ggtagcgcat acgtttttag aggggcaacg
    16021 tttaaaaatt tacgaagctc aactagctga aggagaagga ttacctggac aagttattgt
    16081 caaaaccaaa aaatctttgg taatagctac tggacaaggt gctttgtcct tgatcgttgt
    16141 gcaaccggct ggtaaaccta aaatgtcaat aatagacttt ttaaacggca ttggtagaaa
    16201 acttgaagta ggggacatca ttggcagata attggaaaaa aagtacgcga ggcaaagctc
    16261 tccttgtcat tgaagctatt tttgatcagg gggcttacac aaacatagcg cttaatcagc
    16321 aactaagcaa taaagcttta tctgctaagg acagagctct attaactgag attgtatatg
    16381 gtaccgtttc acgtaaaatt agcttggaat ggtatttagc ccattatgtc aaagatcgag
    16441 ataaattgga caaatgggtt tattatctcc ttatgctcag tctttatcaa ctgatttatt
    16501 tagataagtt accagcgcat gccattgtta acgatgcggt tggtattgcc aaaaatcgtg
    16561 gcaataaaaa gggtgcagag aagtttgtca atgctatttt acgtcaattc actagccatc
    16621 ctctcccaga tatggaaaca attaagcgtc gaaataagta ttattcggtc aagtattcac
    16681 tgcctgtttg gttggttaaa aagttagaag accaatttgg ctccgacaga gcagtggcta
    16741 ttatggagag tttatttgtg cgtagtaagg ctagtattcg cgtgacagac cctttgaagt
    16801 tagaggaagt tgctgaggct ttagatgcag aacgttccct tttatcagca actggtttaa
    16861 ccaaagcgtc aggtcatttt gcagccagtg attatttcac aaatggggac atcactattc
    16921 aagatgaaag cagtcagctt gtagctccta ctttaaacat tgacggtgac gacataattc
    16981 ttgatgcgtg tagcgctcca gggggcaaga cctctcatat agcatcttac ttaaaaacag
    17041 gtaaagttat tgccttagat ctctatgatc ataaactaga gttggtaaag gaaaatgcta
    17101 accgcttagg agttgctgat aacattgaga caagaaaact agatgccaga gaggttcatc
    17161 gtcattttga aaaggatagc tttgataaga ttttggtgga tgctccttgc tcaggaattg
    17221 gtttgattcg tcgaaaaccc gatatcaaat ataataaaga aagtcaagat ttcaatgctc
    17281 tgcaagctat ccagctagag atattgtcta gtgtttgtca aaccttgcgt aaaggtggta
    17341 taataacata cagtacttgc actatttttg atgaggagaa tcgtcaagtc atcgaagcat
    17401 ttttacaaag tcatcctaat tttgaacaag taaaactgaa ccatacacaa gcagatattg
    17461 tcaaggatgg ttatcttatt atcacaccag aacaatacca gactgatggc ttctttattg
    17521 gacaagtcag acgagtcttg tagtatttta ggaggaaact gactgagtca gaaaaaacgt
    17581 atgaagattt cattaaaaac agacattggg caaaaacgct caaacaatca agattttatc
    17641 aataagtttg ataataaaaa aggcatcact ttagtgattt tagcagacgg tatgggtggc
    17701 cacagagctg gaaatattgc tagtgagatg acagtcacag acctgggaag agaatgggta
    17761 aaaacagact tcacagagtt aagtcagatt agagattggt tatttgaaac tatccagtca
    17821 gaaaatcaac ggatttatga tctaggccaa tcagaagact ttaaaggaat gggaacgact
    17881 gttgaagcag tagctttagt tgaatctagc gccatttatg ctcatattgg tgattcacgg
    17941 attggtcttg tccatgatgg gcattatacc ttattgacca gtgatcattc tttagtgaat
    18001 gagttggtta aggcaggaca gatcacagaa gaagaagctg ctagccatcc acaaagaaat
    18061 attatcactc aatctattgg tcaagcttcc ccagtagagc ctgatttagg agtgagggtt
    18121 ttggagccag gggattatct tgtcattaac agtgatggtc taaccaatat gatttcaaat
    18181 gatgaaattg tgactatctt gggcagtaag gttagtcttg atgaaaaaaa ccaagaaatg
    18241 attgacttag ctaacctaag aggaggccta gataatatta caatcgcttt ggttcacaac
    18301 gaaagtgagg acgtcgaatg attcagattg gcaaattatt tgctggtcgt tatcgcattc
    18361 tgaaatctat tggccgcggt ggtatggcgg atgtttattt agcaaatgat ttgatcttgg
    18421 ataatgaaga cgttgcaatc aaggtcttgc gtaccaatta tcaaacagat caggtagcag
    18481 ttgcgcgttt ccaacgagaa gcgcgggcca tggctgaatt gaaccatccc aatattgttg
    18541 ccatccggga tataggtgaa gaagacggac agcaattttt agtaatggaa tatgtggatg
    18601 gtgctgacct aaagagatac attcaaaatc atgctccatt atctaataat gaagtggtta
    18661 gaattatgga agaagtcctt tctgctatga ctttagccca ccaaaaagga attgtacaca
    18721 gagatttaaa acctcaaaat atcctactaa ctaaggaggg tgttgtcaaa gtaactgatt
    18781 tcggcatcgc agtagccttt gcagaaacaa gcttgacaca aactaattcg atgttaggca
    18841 gtgttcatta cttgtctcca gaacaggctc gcggctccaa agcgacgatt caaagtgata
    18901 tttatgcgat ggggattatg ctctttgaga tgttgacagg ccatatccct tatgatggcg
    18961 atagtgctgt tacgattgcc ttgcaacatt ttcaaaagcc tcttccatct attatcgagg
    19021 agaaccacaa tgtgccacaa gctttggaga atgttgttat tcgagcaaca gccaagaaat
    19081 taagcgatcg ttacgggtca acctttgaaa tgagtcgtga cttaatgacg gcgcttagtt
    19141 ataatcgtag tcgggagcgt aagattatct ttgaggatgt tgaaagtacc aaacccctcc
    19201 ccaaagtggc ctcaggtccc accgcttctg taaaattgtc tccccctacc ccaacagtgt
    19261 taacacagga aagtcgatta gatcaaacta atcaaacaga tgctttacag ccccccacca
    19321 aaaagaaaaa aagtggtcgt tttttaggta ctttattcaa aattcttttt tctttcttta
    19381 ttgtaggtgt agcactcttt acttatctta tactaactaa accaacttct gtgaaagttc
    19441 ctaatgtagc aggcactagt cttaaagttg ccaaacaaga actgtatgat gttgggctaa
    19501 aagtgggtaa aatcaggcaa attgagagtg atacggttgc tgagggaaat gtagttagaa
    19561 cagatcctaa agcaggaaca gctaagaggc aaggctcaag cattacgctt tatgtgtcaa
    19621 ttggaaacaa aggttttgac atggaaaact acaaaggact agattatcaa gaagctatga
    19681 atagtttgat agaaacttat ggtgttccaa aatcaaaaat caaaattgag cgcattgtaa
    19741 ctaatgaata tcctgaaaat acagtcatca gtcaatcgcc aagtgcgggt gataaattta
    19801 atccaaacgg aaagtctaaa attacgctca gtgttgctgt tagtgatacg atcactatgc
    19861 ctatggtaac agaatatagt tatgcagatg cagtcaatac cttaacagct ttaggtatag
    19921 atgcatctag aataaaagct tatgtgccaa gctctagctc agcaaccggc tttgtgccaa
    19981 ttcattctcc tagttctaaa gctattgtca gtggtcaatc tccttactat ggaacgtctt
    20041 tgagtctgtc tgataaagga gagattagtc tttaccttta tccagaagaa acacactctt
    20101 ctagtagctc atcgagttca acgtcaagtt caaacagttc ttcaacaaat gatagtactg
    20161 caccaggtag caacactgaa ttaagcccat cagaaactac tgctcaaaca ccttaacaaa
    20221 gaatagttag tctcatgttt tactagcatg ccactaacta ttctttttaa ctactcgtca
    20281 tataaagatg caattttcca ggaattctga taaaatacaa agaaataagg ggaaactaat
    20341 gaaaaaattt caattctttt tacttatcga gtgtatactg ctagctatgg gtatcatgac
    20401 aatcttggat aatgatttat caagttttat cctaattcta gttcttatct tattagcatt
    20461 acgcttttat aaccaagata gccgcaataa ttttttacta actgtcagtt tattgtttct
    20521 ttttttaatt ttcatgctta atccctacat tatcatggct gttcttttgg ggatagttta
    20581 cattttcatt aaccattttt cacaagtcaa aaagaagaat cgctttgcct tgattcgttt
    20641 caaggaagaa aagattgaag tgaacaatac caagcatcaa tggattggta ctgctaatta
    20701 tgaaagtgat tattattgtt ttgatgacat taacatcatt cgaatctcag gaaatgacac
    20761 ggttgactta accaatgtta ttgtgacagg aatggataat atcattgtga tacgtaaaat
    20821 ttttggaaat acgactatat tggtacctat tgatgtcact gttactttag atgttagttc
    20881 catatacgga agcgttgatt tttttagatg tcagcaatat gatttgcgca acgaatctat
    20941 taagttaaaa gaaacggata accaatccct taaaaaagtc aaaattatcg ttacaactat
    21001 tgccggaaat gttgaggtgg ataggcgatg aaaaaacgtt actatgctct tgtttggctc
    21061 tactcaacca ttaccatttt atctattgtt tttgtggtca tggataattt aggaatcact
    21121 tttaactacc ttcgcaatca tttatggcag gtcgaacgtc tagggttttc gattttattg
    21181 ttgattgttt ctgtgacttt attattgttg ttattgtgga ttattatgga tgataacagt
    21241 aagcgtaaca tcaaccaaaa tctaaaatat attctcaata atcgacgact ctatctagat
    21301 gagacatcag aaatcaatac taatttaagt cgactttcta aaaaaatgtc tcacctgact
    21361 gctaacatgc aaaagaaaga aagtgcttat attcttgata gccaagaagt tgtaaaacaa
    21421 gagcgcaaac gaattgcaag agatttacat gacacagtca gtcaagagct attcgcttcg
    21481 tcattgattt tatcagggat ttcgatgagt ttggaacaac tggacaaaac acaattacaa
    21541 acacagttaa caacggttga agcaatgttg caaaatgctc aaaatgatct acgcattctc
    21601 cttttgcatc ttagacctac cgagctagct aatcggactt tatctgaggg ccttcatatg
    21661 attcttaagg aattaacaga taaaagtgat attgaagtca tttataagga aaccattgct
    21721 cagcttccta aaacaatgga agataatctt tttagaattg cccaagaatt cattagcaac
    21781 acgttaaaac atgctaaagc tagtcgaatt gaagtttatc tcaatcaaac ctcaacagaa
    21841 ttacaattga agatgattga tgatggtgta ggatttgata tggatcaggt aagggatttg
    21901 agttatggtc tgaagaatat tgaagaccgt gtcaatgatt tagcaggaaa cctacattta
    21961 attagtcaaa aaggcaaagg agtttccatg gatattagac tgccgatagt gaagggagat
    22021 gacgatgagt aagataaaag tgatattggt cgatgatcat gaaatggtcc gcatgggact
    22081 caagagtttt ttgaatttac aagctgatat tgatgtcgtt ggtgaggcct ctaatggacg
    22141 tgaaggggtt gatttggcat tggctttgaa gccagatgtt ttggttatgg atctagtgat
    22201 gccagagtta ggcggtgttg aggcaacttt agaagtccta aaaaaatgga aagaggctaa
    22261 ggtacttgtg ttaacttcct atctagataa tgaaaagata taccctgtca ttgatgcagg
    22321 agcgaagggt tatatgttaa aaacatcgag tgcggctgaa attttaaatg ccattcgcaa
    22381 ggtttcaaag ggagagttag ctattgaaac agaagttgac aaaaaaatta aggcgcatga
    22441 tcaacaccct gacttgcatg aggaactaac agcgcgtgag tatgatattt tacacctttt
    22501 agctaaaggg tatgataatc agaccatcgc tgatgaactc tttatttcct taaaaaccgt
    22561 caaaacacat gtgtccaata ttctagccaa gttagaagtt gatgaccgaa cccaagcggt
    22621 tgtctatgct tttcgacacc atttagtccc ccaagacgat aattaatgct ataatatagg
    22681 gtatagcaaa ttggaggaaa gtatggacgc aaaactaaaa tacaaagcta aaaaaatcaa
    22741 aatggtgttc tttgatattg atgatacctt gagggtcaaa gatacgggtt atatgcctga
    22801 gtcgattcaa agagtattta aggctttgaa ggcaaaaggc atcttggttg gtattgcttc
    22861 aggtcgcgct cggtacggtg ttccacaaga agttcaagat ttacatgctg actattgtgt
    22921 caaattaaat ggagcttatg tcaaagacga tgctaaaact attattttcc aagctccgat
    22981 tccagcagat gttgttgtgg cctataaaaa atgggcggat gatatgggca ttttttatgg
    23041 aatggcgggt cgtcatgaag cggtgttgtc cgctcgaaat gacatgatta gcaatgctat
    23101 tgataatgtc tacgctcaac tagaggtctg tccggattat aatgagtatc atgatgttta
    23161 ccagatgtgg actttcgagg acaagggaga tggcttgcag ttgcctgctg aattagcaga
    23221 gcaccttcgt ttggtcagat ggcacgataa ctcatcagat gttgtcttga aaggtacgtc
    23281 aaaagcgcta ggtgtttcaa aagtagttga ccatttagga ttaaaacctg aaaacatttt
    23341 ggtttttgga gatgaactca atgacctaga gttatttgac tatgctggta tcagtattgc
    23401 aatgggagta tcacatccat tactgcaaga aaaagcagat tttatcacaa aaaaggttga
    23461 agaagatggc attttatatg ccttggagga attaggattg attgacaaag aattacagtt
    23521 tccacaattg gatttgccaa accataaagg accaaaagca accattaaaa caaaccatgg
    23581 cgatatgacc ctggtcttgt tcccagatca tgctcctaaa acagtagcca atttcttagg
    23641 tttggctaaa gaagggtact atgatgggat tatcttccac cgtattattc ctgaatttat
    23701 gattcaaggg ggcgatccaa caggaacagg aatgggtgga caatccatct atggtgaaag
    23761 ttttgaagat gaattttcgg atgaactcta taatctccgt ggggccttgt cgatggctaa
    23821 tgcgggacca aatactaacg gcagtcagtt ctttattgtt caaaatagta agattcctta
    23881 tgccaaaaaa gaactagaac gtggtggttg gccggctcca attgcagctt cttacgctgc
    23941 aaatggtgga actcctcacc ttgatcgtcg tcatacggtc tttggtcagc ttgtggacga
    24001 aacttcattc caagttttgg atttgattgc tggcgttgaa actggcgcac aggataaacc
    24061 taaagaagac gttatcattg aaacaatcga ggtatttgac taatgaaaat tggcgacaaa
    24121 ctgcatggca cgatcactgg gattaaacca tacggagcct ttgttgccct tgaaaatggg
    24181 acaacaggtc tcattcatat ttcagaaata aaaacgggat ttattgacga tattgatcaa
    24241 ttattggcta taggcaacca ggttttagta caagtaattg atattgatga atatagtaaa
    24301 aagccaagtt tatctatgcg gaccttagca gaagaaaaac agcatttttt ccatcgtcat
    24361 cgttattcca acagtcggca caagattggc tttaggccac ttgaagagca gttacctcag
    24421 tggattgaag aaagcctgca gtttttaaaa aagaacacta aaaagagtct ggaaccttag
    24481 tagttccaaa ccctttttta tttcgtctta attactggta catcatagag ttcagtcgat
    24541 aaatagcgtt cgccattatc tggtaaaata gttaacacat gtttgccttt tcctaactgt
    24601 ttagcgactt caatagcggc gtaaagagca gctccagaag aaatcccaac caggaagcct
    24661 tccttagctc ctgttagtcg agcagtttct aaagcatctt tcgatttaac acggataatt
    24721 tggtcatagg ctttggtatc taacgtgttt gggataaatc cagctgatat accttgaatt
    24781 ttatgtggtc caggctcttg accagataag acagcagatt cttcagcttc aacagcatag
    24841 ataacagttt cagggctagc ttttttcaag acatgtgaaa caccagaaag tgttcctcca
    24901 gtaccaacac cagatacgaa tgcatctaaa gaaatctctt taaaagcttc caaaatttct
    24961 tgagctgttg ttttttcatg gatgcttgga ttggcagggt tattaaattg cataggcatc
    25021 caagcaccta gttctattgc taaagtttca gcttttgcaa tagccccttt cataccttct
    25081 gctccaggtg ttaagacaag ctctgcacca taagcctgaa tgatttgccg tctttccaag
    25141 ctcatagttt cgggcataac aataatgact cgataccctt tagcagcacc tacccatgca
    25201 agaccaatac ctgtattacc acttgttggt tcgataataa cgtcaccagg acttatcaga
    25261 ccttcagctt cagcagcttc aatcatcgat aaagcaatac gatctttaac agaagatcct
    25321 gggttaaaag cttctaattt tacataaacg tcagcagctt cgtttggaat taaacggtta
    25381 agtttgataa taggtgtttg acctactaat tctgttatag ttttgtaaat tttagtcata
    25441 gtttagcctc ttttcttgat acaaaataaa tacgctgtgt atttaagtat aaggagagat
    25501 attattaaag taaaatacag atttactatc actctgataa taaagccata tcacttttgt
    25561 tgatgattaa tcacagggta attcaataac tttggatccg attttctcac agcttatctg
    25621 accatgataa taatttgtta aagtatcaat gagattttcc acacgttcag tatcacaata
    25681 aagtgttgtc tttatcgtgt ctgaaaactt agtttctgtt tcggttaaag ccaattgatc
    25741 tagcaagtta gagtatagtt gatattgggg ataagaaagt gtgatttcta gtcctatctg
    25801 ctgtttaact tcaatgatgc caaatcgttt aatagctgtt gcggtcatgt tagagtatgc
    25861 tctgattaac ccacctgttc ctaatttaat accaccaaag taacgcgtta ccacaactac
    25921 tacatttgtt aaacactgct tttctaacac agaaaggata ggtattccag cagttcctga
    25981 aggttcacca tcatcacttg agcgcttgat ctgtctgttg ttaccgataa tcatcgcaaa
    26041 gcaggaatga ttagctttgt aatgttcttt tttgatagca ttaacaaaat tcttaccatc
    26101 ttcttcagtg ctcactcgtt tgatatgaca aatgaaacga gattttttaa tactttcttc
    26161 gaaaaaacca ctggctttga ttgtcttaaa atgttccata aaaaaattgt acaagaaaag
    26221 ataaaaatta gcaaaaaaaa gcgaataata aagtatggag tctattgaaa atagttatgg
    26281 acggttgttg ctagaaagcc agttaccaga ttcagcaaag cagcttgctc aacctttaaa
    26341 aagtgtagta atattgagag gaaaaatgat ttgtcaacgt tgtcactatc agcttgatga
    26401 agaagcacga ttgccaagtg gcgcctatta ttgccgattt tgtcttgtct ttggacgaaa
    26461 tcaatcagat aaattgctct atgctatccc acctatgcat tttccaaaag gtaattatct
    26521 ggtttggggc ggtcaactaa ctgcttatca agagatgatt tcccaacaat tattaatcaa
    26581 tatgcaaaat caaaaaacaa cattagttca tgctgtaact ggtgcaggaa aaacagaaat
    26641 gatttatgct gcgattgagg cggtaattaa cacaggtggc tgggtttgca ttgccagccc
    26701 aagagtagat gtttgtgtag aggtggctac tcgtttatcc caagccttct cctgcagcat
    26761 ctgtttaatg cacgcagagt ctcttcctta tcaaagagct cctattatag tagccacaac
    26821 gcatcagctg ctaaaatttc acaaggcttt tgatctctta attattgatg aagtagacgc
    26881 attccctttt gtaaataata ttcaacttca ttatgctgca agtcaggctt taaaagaagg
    26941 tggcgcaaag attttattaa ctgcaacttc aactagaact ttagaaagaa aggtaaacaa
    27001 gggagaagta gtcaagctga cattggcgag acgctttcat aataggccat tagttattcc
    27061 aaaatttata agaagtttta atctatttaa aatgatacat cggcaaaaac ttcctcctaa
    27121 aattttaaaa tacttaaaaa aacaaagaaa aacaggctat ccccttttaa tttttctacc
    27181 cactattata atggcagaat ctgttacagc aatcttaaaa gagttattgc ccgccgaaca
    27241 aatagcttgt gtttctagtc aatcacaaaa caggaaagaa gatatcacag cttttcgtca
    27301 agggaaaaaa acgattttaa ttacaacaac aattttagaa aggggtgtga catttcccca
    27361 aattgatgtt tttgttcttg ggtctcatca tcgtgtctat agttcccaaa gtcttgttca
    27421 aattgctgga cgagttggaa gatctataga cagaccagac ggaacgttat atttctttca
    27481 tgaaggtatc agtaaagcaa tgctactagc aagaaaagag attaaagaaa tgaattataa
    27541 agggtattcg catgatctgt ctactatgtc aacaaattag tcaaacacca ataagtatta
    27601 cagaaatcat ctttttaagg cgtatctctt caccgatttg tcaacaatgt caaaaaagct
    27661 ttcaaaagat aggaaaaagt gtttgtgcga catgttgtgc aaactcagat ataatagctt
    27721 gtcgagattg tctaaaatgg gaaaacaaag gatacaatgt aaatcataga agcttatatt
    27781 gttataatgc tgctatgaaa gcatacttca gtcaatataa gtttcaagga gactatttat
    27841 taagaaaagt ttttgcagta gaacttgccg atgttattac caagtactat aaaggctata
    27901 tcccagtccc ggttcctgta agtcccggtt gttttcgaga aagacaattt aatcaagtga
    27961 gcgctattct tgaggcagct aatgtcagct acctttctct ttttgaaaag ctagataata
    28021 ctcaccaatc ttccagaaca aaaaaagaga gattattagt agaaaaatct tatcgactac
    28081 taaaagtatc aaacattcct gataaaatcc ttatagtaga tgatatttat actactggta
    28141 gtacaattat cgctcttaga aaacaattgg ctaaagtagc aaatagtgac attaaaagtt
    28201 tgtcaattgc acgttaaaac ttgcaaattt tcatgaaagc agtataatag tattaaagat
    28261 aaagtaagcg cttcaagcgc gagaaagagg tatcctatga ttaagttcag tattcgtgga
    28321 gaaaatatcg aagtgacaga agctattcgc gattatgtag aatcaaagct tactaaaatc
    28381 gaaaaatatt ttgctaaaga ccaagaaata gatgcacgtg ttaatttaaa agtttatcgg
    28441 gagagatctt caaaagttga ggtaacgatc ccattagatt cagtaaccct tcgtgctgaa
    28501 gatgtttcac aggatatgta cggctctatt gatttagttg ttgataagat cgaacgccaa
    28561 attagaaaaa ataaaaccaa aattgctaaa aaacatcgcg aaaaggttcc aactggtcaa
    28621 gtctttacaa ctgagtttga agctgaagaa gtcgatgaga taccagaagt acaagttgta
    28681 cgtactaaaa atgtgacatt aaaaccaatg gatgttgaag aagcgcgttt acagatggaa
    28741 ctattgggac atgatttctt tatctacact gattctgaag atggtgcaac aaacatttta
    28801 taccgtcgcg aagatggaaa cctaggatta atagaagcta aatagttcac aactaaaacc
    28861 tacagggatg attatacgta ttttaaaagt gggaaaaagc tattcatgtt tagaggtgac
    28921 atgatgaaaa tgagattaag tgatagatac gacagtcatt atgctaacaa aagtatctat
    28981 tacagttcct ctttaagtaa atcttacgta aaattagttt gaaaaaagat tagtcccaat
    29041 tctgggctag aaattctcaa aaaatatgaa aaagcgcgtt ttcagaatat aaagcgcgtt
    29101 tttttctttt tccatttaac aataaaaaaa ctcatgacga acatggtatc ataagagaat
    29161 ttttactttt taaacaaagg tcaaagactt tctgacacca aataaaaata gaattttttc
    29221 taactaaaaa taatagcaca atctttggca gcaatctgaa ttgtttttcc atacgtttgc
    29281 ttaaaatata ggttatgtga cgtgcgtgca agatcagatt ataacaaaat agttccaaat
    29341 aagcctatca ctgagaaagc atcacagaag ggttaaactt tttttgtatt agcgttttat
    29401 cagtacaacc taacacttat ttttataaaa aaataaaaaa gctattgaca atcttataca
    29461 agataacgta tactaataaa gctgttgtaa atatggtaaa gcaatagatg ctatcaggaa
    29521 aaaatgtgaa
//
LOCUS       DAUGSW010000018        28617 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUGSW010000018 DAUGSW010000000
VERSION     DAUGSW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28617
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.018"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..155
                     /locus_tag="VIB18_000977"
     CDS             <1..155
                     /locus_tag="VIB18_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765994.1"
                     /translation="SLFMIATAAVAGLSLATLGEHQTVSANDASYSNGFYGHTGPDSW
                     LLYTVW"
     gene            567..773
                     /locus_tag="VIB18_000978"
     CDS             567..773
                     /locus_tag="VIB18_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765995.1"
                     /translation="MKKKLSLFMIATAAVVGLSLATPENQTVSASETTTTQACDYSFY
                     GYCGPISWLFYNTRDFLFGSTTVK"
     gene            complement(1058..1435)
                     /locus_tag="VIB18_000979"
     CDS             complement(1058..1435)
                     /locus_tag="VIB18_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8765996.1"
                     /translation="MKQQSYQPLRFVYLVVALFAAMLLIARPVMADEEDKDPWRLGYN
                     QGLTKGKEDGKVAEWTDLTPPDPEVPKSPKDIDDSNHEHYRDGYKDGYKEGYNEGFGG
                     SYPLLIPVQFIWGLILHWWGKLN"
     gene            complement(1690..3405)
                     /gene="slo"
                     /locus_tag="VIB18_000980"
     CDS             complement(1690..3405)
                     /gene="slo"
                     /locus_tag="VIB18_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEQ8765997.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTSEQPKPESSELTIEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKDLQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRT
                     EYVETTSTEYTSGKINLSHRGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(3429..3914)
                     /locus_tag="VIB18_000981"
     CDS             complement(3429..3914)
                     /locus_tag="VIB18_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEQ8765998.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSIVANMTKALKDAHIREAMAHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(3919..5274)
                     /gene="nga"
                     /locus_tag="VIB18_000982"
     CDS             complement(3919..5274)
                     /gene="nga"
                     /locus_tag="VIB18_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEQ8765999.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFASPM
                     HIGRVLIVNGDTSSKENYYKKNRIAKADVKYYKGNKLVLFHKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNIERDIFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAIQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            complement(5645..6184)
                     /gene="nusG"
                     /locus_tag="VIB18_000983"
     CDS             complement(5645..6184)
                     /gene="nusG"
                     /locus_tag="VIB18_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEQ8766000.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(6357..7400)
                     /locus_tag="VIB18_000984"
     CDS             complement(6357..7400)
                     /locus_tag="VIB18_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8766001.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIETAK
                     KAIIEGTITVPEN"
     gene            complement(7727..9019)
                     /locus_tag="VIB18_000985"
     CDS             complement(7727..9019)
                     /locus_tag="VIB18_000985"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEQ8766002.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGERIDHYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVCISTFSVGPGREQTNILESVWASI"
     gene            9457..10335
                     /locus_tag="VIB18_000986"
     CDS             9457..10335
                     /locus_tag="VIB18_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766003.1"
                     /translation="MIRKYDRTSTKNKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            10348..11610
                     /locus_tag="VIB18_000987"
     CDS             10348..11610
                     /locus_tag="VIB18_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEQ8766004.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTRA"
     gene            complement(11730..12356)
                     /locus_tag="VIB18_000988"
     CDS             complement(11730..12356)
                     /locus_tag="VIB18_000988"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEQ8766005.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLEETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(12401..13816)
                     /locus_tag="VIB18_000989"
     CDS             complement(12401..13816)
                     /locus_tag="VIB18_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEQ8766006.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(13817..15592)
                     /locus_tag="VIB18_000990"
     CDS             complement(13817..15592)
                     /locus_tag="VIB18_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEQ8766007.1"
                     /translation="MNQGKIITVSGPLVMASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEAGKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            complement(15793..16113)
                     /locus_tag="VIB18_000991"
     CDS             complement(15793..16113)
                     /locus_tag="VIB18_000991"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEQ8766008.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(16110..17108)
                     /locus_tag="VIB18_000992"
     CDS             complement(16110..17108)
                     /locus_tag="VIB18_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEQ8766009.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            complement(17124..17708)
                     /locus_tag="VIB18_000993"
     CDS             complement(17124..17708)
                     /locus_tag="VIB18_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEQ8766010.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(17776..18255)
                     /locus_tag="VIB18_000994"
     CDS             complement(17776..18255)
                     /locus_tag="VIB18_000994"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEQ8766011.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(18257..20257)
                     /locus_tag="VIB18_000995"
     CDS             complement(18257..20257)
                     /locus_tag="VIB18_000995"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEQ8766012.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQASQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKQHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(20247..20567)
                     /locus_tag="VIB18_000996"
     CDS             complement(20247..20567)
                     /locus_tag="VIB18_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766013.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(21021..22040)
                     /locus_tag="VIB18_000997"
     CDS             complement(21021..22040)
                     /locus_tag="VIB18_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEQ8766014.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(22077..22442)
                     /locus_tag="VIB18_000998"
     CDS             complement(22077..22442)
                     /locus_tag="VIB18_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8766015.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            22616..23296
                     /locus_tag="VIB18_000999"
     CDS             22616..23296
                     /locus_tag="VIB18_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8766016.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(23418..24065)
                     /locus_tag="VIB18_001000"
     CDS             complement(23418..24065)
                     /locus_tag="VIB18_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8766017.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(24068..24727)
                     /locus_tag="VIB18_001001"
     CDS             complement(24068..24727)
                     /locus_tag="VIB18_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8766018.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANQA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(24739..25923)
                     /locus_tag="VIB18_001002"
     CDS             complement(24739..25923)
                     /locus_tag="VIB18_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8766019.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTLLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            26044..26955
                     /locus_tag="VIB18_001003"
     CDS             26044..26955
                     /locus_tag="VIB18_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8766020.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEVKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKTSHLKHYIKHTILDYFTNQRF"
     gene            complement(27027..28433)
                     /locus_tag="VIB18_001004"
     CDS             complement(27027..28433)
                     /locus_tag="VIB18_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEQ8766021.1"
                     /translation="MNNSKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
BASE COUNT         8685 a         6132 c         5013 g         8787 t
ORIGIN      
        1 tatctttatt tatgatcgca actgctgctg ttgcaggcct tagccttgca acactgggag
       61 agcaccaaac tgtttcagca aatgatgcta gctatagtaa cggtttctac ggacacactg
      121 gtcctgacag ctggttactt tacacagtat ggtaaacctc ataccgtaac atagaagcta
      181 tcttcttcgt aagactacgg ttatgaaaag cctaaggctg cataagcagc cttaggcttt
      241 ttgattggct aaaacgtttt tgccaatgac ccctcaaggt aaaaaagaaa aggcataccg
      301 cctataaaag gagaggagcc caaaacacaa gtcgtaacag ttgctagcta accagcacca
      361 aaaaagctgt aacacctcaa atagaatgat aaccagatta atattattag taattcatgt
      421 gatttttata atataaataa atgctttaat attagatttc tttgcctttt tcggtcaaac
      481 acatcacaaa aagattaaaa tgtgatattg aatcgttaat ataatatgag tataatatag
      541 gtatactata atttaaggag ttacaaatga aaaagaaatt atctttattt atgatcgcaa
      601 ctgctgctgt tgtaggcctt agccttgcaa caccagaaaa ccaaactgtt tcagcaagtg
      661 agactacaac tactcaagca tgtgattaca gtttctatgg gtactgtgga cctatcagct
      721 ggttattcta taacacaaga gattttttat ttggtagcac tactgtaaaa taaaaaaatc
      781 tcttcatagt gagactacag ttataaaaaa gcccaagctc gcttacgcag tcctgggctt
      841 ttttgctgtc ctaaagtcaa ggtgtggcca caacttcaaa cccaaagaca attaaaccgc
      901 accccaacaa ttagacatag gctatgtccc cagaatcctg gacacatatc actaaagcct
      961 aatgattaag gtgcggtagc aaggaactgt tttaaattcg tctgcgtcta actataccca
     1021 ctggctatgg agtcagctta gagttgattg tcaaatgtca gttcaacttc ccccaccaat
     1081 gtaaaatgag tccccatata aactgaacag gaattaacaa agggtagctt cccccaaatc
     1141 cttcattata accctctttg tacccatctt tataaccatc tctataatgc tcatgattag
     1201 agtcatcaat atccttaggt gattttggta cttcagggtc aggtggggtc aaatcggtcc
     1261 attcggctac ttttccatct tctttcccct ttgttaaacc ttggttatag cctaatctcc
     1321 aagggtcttt atcctcctca tccgccataa caggtcttgc tataagcaac atagcagcaa
     1381 atagagccac cacgaggtag acgaagcgta gaggctggta agattgttgt ttcatgataa
     1441 tagttatctc tcccttttat gttatgcttt acttgttaaa aaacagcttg ttagtattat
     1501 agattagaag caacttagct tcaaggtcac gatgtgagaa aaaaataact ttttgatata
     1561 ctaatcaaaa aagcttgtct atgaaggtat ctcatagaca agcttttttc tgtatttgtg
     1621 agaggagtag gcacaaggcc tcaagagata agcagcatca aagtgcttga cgaacctctt
     1681 gaaccagtcc tacttataag taatcgaacc atatgggctc agggttgatc ctgagatgtt
     1741 gacattgatt tctttagaca gtttcacatc tctttcgtcg atcacttttc gccaccattc
     1801 ccaagctaag ccggtgcact ctctagccat gatacggata tttcgtgaat tagctcctag
     1861 tgggataact gtgctaaatg gtgatgtctt actataccag ttgttgtccc aacgtcgttt
     1921 tgtaatcact tcttttcctt tgtcatcata attgatttca tcccaaagga tttcatattg
     1981 agcaacatac gcgccgcgat gagacaggtt aatttttcca ctagtgtact cggtagatgt
     2041 tgtttcaacg tattcagttc tgttattgac acccgcaatt ttattatttt taaggaaaac
     2101 actggtgtat gaaataggat aagctgggtt ttttctactg aaagtagcat tgtctttgat
     2161 aacgtttcta ataacatcaa agtcttttgt gactacctta ttgtgctctg cagcatctcc
     2221 tcctaaaacg acagctgtaa atgaactatt ttctaagata tcagagtatt ttccattcgt
     2281 tttaacatct gttcctttta gagctgcact aaaggccgct tcaacatcat tacttttaga
     2341 acttgtttct agtttgacaa aaacagttcg accataggct acgttactca caaagagtgg
     2401 cggagcttca ttgctgacac cttttcgttg caaatcttta aaggtcactg atttatcaaa
     2461 cacatccgca ggattattag gaaggtttgc tgatacggtg taaaagattt gcttgtatgc
     2521 tgcaatcatc accttctttt caccttttga aatcgacttg aaatcaatgc ctaaagtacc
     2581 atctaagatt ttgctattaa catttagagc tgcttcaatc tgtgacttag aatataccat
     2641 tgattcagta tattgtgttc tggcaggaag cgtattacca ccagaataat tatcatgcca
     2701 ttggttaaca agattatcaa tagctgttga aacattggca taggtagggt cattgacctc
     2761 aaccgttgct ttgtctccca tacctggtaa atcaatatgg attttttgtg ggtttcgctt
     2821 ggtgactacc gcgtctggtt tgttttcggt aaaaccttta tcagccagct gaagggctgc
     2881 tggataggtc atatcagtga cagagtcaat gatggaaata tcgactggtg tagtgttgat
     2941 attttttttc tttctttcaa tgacaataaa tttatcagct ttcttaacgc cttctttagg
     3001 aacaaaattt tcaatggttt caccattttt agcaagtact tcaagctcat tataatttag
     3061 tgaataaatc ttgtcattga tttcttcagt gtgatcttct tcgctctttt ttttgtcttc
     3121 tgactttttt tcttcttttt ctgcagattc tagtggcatt tctttgggag caagcttaat
     3181 catatcgtta gagttaagca tatcatccat tttctgacct gctttttcga tagttagctc
     3241 actactttct ggttttggtt gctcacttgt cgttgtggtt tctgtactag cagtgttttg
     3301 tttgttcgat tcagcattag cagtaacaag attaccaatg ataagagctg ccgttagtag
     3361 cccagcgacg cgactgtatt ttttaaatgt ttttttatta gacatgtcct tcataccttt
     3421 ttatcattct aaaatgtttc tattgttctt tcgaccatat caagcatagt atcttgatag
     3481 tgagcaaatt ctcctaattt gtaatgtgcc atagcctctc taatatgcgc atcttttaac
     3541 gctttggtca tattagctac tatgctttga cggtttaaat aaaatggcaa gctttcgtaa
     3601 taatttaata acatgttttc agcgtttagg gtttgaaccg cttggtaaat gtctaatgct
     3661 tgaccgctat ttgacatttc taataatgct tcttcgatgt tagctttcaa ttgggtatag
     3721 ccttttatga aagcagggta aaccccatac tctaaaataa cttctggatc agaaatatct
     3781 cccatataag agtctctcct agtgatacga tactctttgt cactacctat caagtatttt
     3841 tttaaatcat taacagttac ttctttttga aacatttttt ggtaatgttc taaacccttt
     3901 ggcaccttat acatattgtt acttcctatc ttgcattcta tcttgcattt tcttaatttt
     3961 gaagcgacca gttacttttt tatggtcacc atttggagca atgatggtag gatcaataat
     4021 ttcaaaatag cctttggcat caatctctgc taagacagct ttagatttta gatctttaac
     4081 actaatcgat gggaaaatta attcactttc tgaattttca atgtgttttc ctgaccacgt
     4141 ttggcaacca ggaatgttga gcgaatttgc tccaggagta tctccgctag ctgttcggat
     4201 atagcctagc ttatcaatgt tttttgttag ttcagaatcg tactcatatt gataaacccc
     4261 atcactatat tttccgctat cgacaccttt tatattttca atttggtcag ctgattttaa
     4321 cttaccttga tcagtaaaga gcaatgccat atcttcagca aaacttgtca caaaaagacc
     4381 gttttcttgt cgaccaatcg ttgactttct tttagcatcg tcaaaagcta acatcaaatc
     4441 ttttttgctt gtaacgtggg aagctccgct ttctttgtag acttgtttta gtttttcaac
     4501 aaactctttt ttgtagtggt atttgcggct aacatacatc cggtaatact cagcacgtga
     4561 cgcaacagca gacatctgaa tagctttatc agcatacttg tcggcagttt caataaactc
     4621 atctgcttgt ttatctgtta cccatttatc tttaatttct ttaaactttt tttcaaaaat
     4681 atcgcgttct atattgccaa aagtgacctc tgacaaggct aaaatatcct tgttttgtcc
     4741 ctgatggacc tctgttacct caatatcaat acgatcaaca tctaattttt tatcaatctc
     4801 aatgtgatgc ggttttttag tgtaggtgtc gcctaattca attttgtgaa agaggaccaa
     4861 tttattccct ttatagtatt taacatcagc ctttgcaatt ctatttttct tgtagtaatt
     4921 ctccttgcta gatgtatctc cattcacaat taaaactctc ccaatatgca tcggggacgc
     4981 aaacttgtag gaaagtactt caccaacacc accaccaggt gaattttcct cccagacagt
     5041 actcattgag ccgtctaatg tgtgcatgac atgattgtct tctttagagg aagttgcgtt
     5101 agcttccata actttggtcg tttcatattt gacatcgctt tttttatttt ctttgccact
     5161 aacagcgtac gttgtgctat tagctaataa actgctaccc attgctccag ccaaagcaat
     5221 agcaacactt gtctttgcga caatatgagc taatgttact tttttgtttc tcatgtaaac
     5281 caccttatat tatttttaag taaactatac attagcaaat agtttttgtc aatgcgattt
     5341 attaacatcg ttttagactt ttctatcaaa aaaatgaaca caaaaaaaca agtagccaac
     5401 tgttacaagt ttcaagggga tatttccatc ttattatcac agaaccttca catctgttct
     5461 atttaaacca gattaaaagt actagttaaa tatttgatag tagcaccgtt atcagtaata
     5521 gatctgttaa ttatctctga ttacaatgat gttaacgata gtcatacctt tgtttgtaca
     5581 cacgcttcac ttccaactaa aaaaggtctg atggtaatat ttataccatc agacctttga
     5641 gagcctatag ttctgcaatt tgataaagtt caacttctgc tactgtttca gagccaaaca
     5701 tgttgagcat cagcttcact ttgttgtttt cgatttctac cacacgacct tcttgtccca
     5761 taaaggcacc gtctatgatc tgaaccacat cgccttcttt gatattggta tcaaagacat
     5821 caatggtttg ccccatagac aacaagatag cacggatttc ttcttcaaga agtggtgttg
     5881 gttttgatcg gttcccgtgt gatcccacaa aacctgtaac gtttggtgtg ttacgcacaa
     5941 caaaccaagc ttcatctgtc atgaccattt caaccaagac ataccctgga aagcgatttt
     6001 cttcgatttc tttggtttgc ccattttttt caacgttaac cgtttgtgtc ggaatttcga
     6061 cgcgcaaaat attgtccaac atgttatagg tttgggcacg ttgcaagagg ttttctttta
     6121 ctttgttttc gtagcctgag taagtttgga ggacgaacca gcccttatca aatgaatcta
     6181 gcatgatgtt tcctttcatt ataaaaaagc cctttatttg gcttttgcgc tgttttctat
     6241 caccttcatt ataataaaag acagggccgc tgtcaacgta tctgtggagc tacttgacac
     6301 ctttattaaa aagtccaaag tcggttcgtg acgactctgg acggtattgt acagttttag
     6361 ttttcaggaa ctgtgatggt tccttcgata atcgcttttt tagcagtctc aatagctttt
     6421 ttagtgtctt gtgtcagagc atccgttgta agactaacac caccttcttt taaaccaaaa
     6481 gtggttattt gaccacctgg gaattggcct tctgaggttt ttacggctac ttttactaaa
     6541 gcttttccga cttccttgat acttgaggtc aaaacaaaat tagctgactt gccatctttt
     6601 gtggtgtatt ttccatcttc actttggtca cggtcaacac caataaccca aaccttatct
     6661 tcttctttac gtttttcgtt gatagactta gcttcgctaa agacacccgc ccctgtgcct
     6721 cctgctgcat gataaataac atctgcgcct tcagcgtatt gagcagctgc aatcgtcttg
     6781 cctttggcag catctgcaaa agagcctgca taagcaactc ttactttgat ggtatcatct
     6841 actgatttca caccagcttc aaaacctttt tcaaagcgct tgacaacatc tccttccata
     6901 ccacctacaa aaccaacttg cttggttttt gtcgttttag ctgctgcaac accggctagg
     6961 tatgccgctt catggtctga aaaggtgata cttgcaacat ttttttgacc tttaatcaca
     7021 tcatccacaa ttgcaaaatg gttgtcagga ttgtttgcgg ctactttttc tacagcgtca
     7081 tgtaatggaa atccaatccc aaaaacaaga ttataaccat tggttactgc tgactcaagg
     7141 tttgtggtaa actctgattc attggctgat tggaaataat catagccttt tcctttttca
     7201 agtttatttt cttttcccca agcttgcaag ccttcccagg ctgactggtt aaatgacttg
     7261 tcatcaatac ccgtctgatt agtaatcata gcgattttta atgaattgtc agttgtttgt
     7321 ttagaggagt tattggtaca gcctcctaat gtgaataggg cagtcgaaac aagaccaagt
     7381 gacattactt ttttgttcat gtgaaaatga acctcctaaa tgtttaatcc taaagtgatg
     7441 tgtcattgtt aacgttctac ttatgctcta gaacgaaaag tttagtatat caaaaaaatc
     7501 agttttatcc tactattttt gttgaaaaat ctctttttca ccaaaatgac cgaacaataa
     7561 agtgagatca actggtaaat cccattatct cctcaaaaat cacctcttaa ggagataagt
     7621 caacgacaaa actcaagcta ctagtaatag catgactaac tatacaatcc aacaagcggt
     7681 aaaaagagct ggaaacgcta tccaactctt tgtcatacta gacaccttag atagatgccc
     7741 agaccgactc aagaatattg gtctgttcac gtcctggacc aactgagaag gttgaaatgc
     7801 aaacgccaac caattctccc acgcgacgaa cgtagttgcg ggcattttca ggcagctcat
     7861 caaggctacg aacacctgtg atgtcctctt gccagcctgg taattcttca tagattggtt
     7921 tgcaacgttt gagttgttca agacttgctg ggtagtgatc aatacgttca ccatctaaat
     7981 cgtaagccac acaaatctta accgtatcaa gtcctgaaag aacgtcaatg gaattgaggg
     8041 aaaggttagt aatccctgac acacgacgac tatggcgcat aacaactgag tcaaaccaac
     8101 cgacacgacg tggacggccg gtcgttgtcc cgtactcatg acccacttca cgaatgcgct
     8161 cacccacttc atcaaagagt tctgtaggga atggcccatc accgacacgg cttgtgtagg
     8221 ctttacagac accaactact ttgttgattt tacttgggcc aacaccagaa ccaatggtta
     8281 caccaccagc aactgggttt gaagacgtta caaatgggta agttccttgg tcaatatcaa
     8341 gcataacccc ttgtgcacct tcaaaaagaa cacgtttacc ggcatcaagt gcatcattta
     8401 aaattacaga agtatctgtc acatattgct tgatttcttg accgtaagca tagtattctt
     8461 caaaaatagc atcaaaatca agaggtgtac tgtcatacat tttttcaaat aaacggtttt
     8521 tctcagctaa attaatgcgt aggcgctctg caaagatatc cttatccagt aaatctgcga
     8581 tacggatacc aactcgagca gctttatcca tataagctgg accaatccct ttaatagttg
     8641 ttccgatttt attgtcacct tttgcatctt cttgcagttg atccagctgg atatgataag
     8701 gtaaaatgac atgagctcgg tctgaaatgc gaaggttatc tgtcgtcact ccttcatcat
     8761 gcaggtacgc caactctttg accaaagatt tggggttgac cacaacgcca ttaccaataa
     8821 cggaaatttt ttgcgggaag aaaattcctg atgggatcaa gtgaagttta aacttcttac
     8881 catcaatcac gatcgtatga ccagcattat caccaccttg atagcgtgca attacttctg
     8941 catccgctga caagaaatca gtgattttac ctttaccttc gtcaccccac tgggtaccaa
     9001 caacaactac agatgtcata tcattgtcct aactttctga aacacttatt ctcaataaaa
     9061 atcataggca agctaaccac tgcttaaaaa ccaaaaagaa ggtcagatct gtaagatcag
     9121 caatgtagct cttgatattt aaagaaaaca ggcaggaatc tcacctgcta gcatatatct
     9181 tacaacttat tatagcaaaa aatgattttt tctgctagat ttcttagcat tattaaggaa
     9241 aaagagaaac tcttttttta accatgataa acaatcctaa aaaaacgaac attataagag
     9301 aaaagctttt aacctcgttt ctcctaagct ttagcagggt taaacgattc tcttaaaaca
     9361 ttagctcttt tctttcagaa atagtggttt taaggtaaaa taatagtaag ttacctctat
     9421 gagatagcca gtaaaaacat atcgaggaaa tatcacatga ttagaaagta tgaccgcacg
     9481 agcacaaaaa ataaatcact aaactggatt tggctaatca ttgctttttt tatgatttca
     9541 agctttatag gtggctcttc ttttactgag tcacttctag acattttgcc tgccatagcc
     9601 attggtggta caggttatgc tatttttcgt gttagatctc atcaaaagcg gctagcaaag
     9661 gccaagattg ccaaacaatt agaagatcta aaagcaaaaa ttcagctagc tgatcgtaaa
     9721 gttcggctgt tagacactta tctggcagac catgatgact tccaatataa cgtacttgct
     9781 cagcaattat taccacaact tagtgacatc aaagcaaaag ctattacgtt aaaagaccag
     9841 ttagatccca aaatttatcg tcgtatcacc aaaaaagcca atgacgttga aagtgatatt
     9901 acccttcaac tcgaaacact gcagattgcc acaactctta accctcagcc tttgaaaacc
     9961 ccatctccta atcttattaa caaagcacct gagctcaaac cgtattatga taatattcag
    10021 acagatcatc aagctatcct tgctaaaatc caaggagccg acaatcaaga agaattgctt
    10081 gcgctgcatg aagctaacat gagaaggttt gaggatatct taacaggcta cttaaaaatc
    10141 aaagaagaac ctaaaaatta ctataacgct gctgctcgtt tagaacaagc caaacaagct
    10201 atccaacaat ttgatgaaga tcttgacgaa acccttcgtc gactcaatga aagtgacctt
    10261 aaagattttg atattagcct tcgaatcatg caaggtgcta ctcaaagacg aacaacgcat
    10321 caccaaaaag actaaaggag tccctttatg gcagatttta attttgacat tgaccaaatt
    10381 gctgacaatg ctgttgtcaa aaccgataaa actaccgata ttatctcaga cttaccaact
    10441 gacacaaatg gccaaatctc tttttttgag aaactaagtg ctgaccagca gacagctatt
    10501 actgccaaag ccccggcatt ggtagatacc tttttggcag accaaaatgc gctacttgat
    10561 tttggtcagt ctgctgttga aggggtcaat gcaacggtta atcatatctt ggcagagcaa
    10621 aaaaaattac agattccaca agtggatgat cttttaaaat caaccaatcg tgaactcaat
    10681 ggttttatcg ctaaatacaa ggatgccaca cctgtggacc ttgataaaaa gccaaacttt
    10741 cttcaaaaac tctttaaaca aagccgtgat accctgcaag agttttattt tgattctcaa
    10801 aacattgagc aaaaaatgga tagtatggct gcagcggttg tcaagcaaga agatacctta
    10861 gctcgcaata ttgtctcagc agaattgtta attgaagata atactaagtc cattgaacat
    10921 ttggtaggcg tcattgcttt tatcgaagct agtcaaaaag aagctagtca gcgcgctgcg
    10981 gctttacaaa aagacctaaa aaccaaagac agtgctacac cagactatca aataaaagct
    11041 gatcttttgg caagaactac cgaagtcatc aacaccctcg aacaacaaca caccgaatac
    11101 ttgagtcgcc tctatgttgc ttgggcgaca actccgcaaa tgcgtaatct agtcaaggtc
    11161 tcttctgaca tgcgtcaaaa actaggcatg ttacgccgca ataccattcc aacgatgaaa
    11221 ctatctattg ctcagttagg catgatgcaa caatcggtta aatctggaat gactgctgac
    11281 gccattatta atgctaataa tgctgccctt cagatgctag cagaaacaag taaagaagcc
    11341 atcccagcat tagaacaatc agcacaaaac cctactttgt ctatgaaatc tgtgacaagt
    11401 ctggcagaaa gtttagtagc acaaaataat gggatcattg cggcgattga tcatggacgc
    11461 aaagaacgag cacaactaga aagtgctatt atcaggtctg ccgaaaccat taacgattct
    11521 gtcaaactac gtgaccaaaa tattgtgcaa gcacttctta gtgaaggcaa ggaaactcaa
    11581 aaaacaattg ataaaacaac tcgcgcataa gctaaacatc acctgtcacg ctacttaaaa
    11641 agcaagtcat cagttaggtt aatccctttg atggcttgct tttttactac ttaacgaata
    11701 atcgccttgt ttgatataac acttatcttt tatgatgtta ttttcataat acgaacaagg
    11761 ctagcacgct cggcctcttc taatttcaac tcaatgtagt gaatcgtctc ttccagttgc
    11821 gggataatag aatactctaa gccattgacg cgacgtctag tcttttcaat gtcatcagcc
    11881 attagttgac aagttttttc aacttcagct aaccgtaaga gcttttctaa tagttctttt
    11941 gtcttttgga tagtattgtc catctcacta tttgagctga ggtaactata agcaaactca
    12001 ccttgttctt gctctcttgc cgtattagac tggacatgga atttaggcac attgacactc
    12061 atgatatttt caatatcaat ccataaggtc acttcatgga ctggaacagc aaagagttct
    12121 tctaccatta gactattttc agatgctttt gccaagacaa actccttcat attggcagca
    12181 agttcttttt cgatagtttg acgaagctca ttgttttcac gaattaaatc aacgaagcgg
    12241 cgcatcaatt catctcgctt gtcctttaat aatttatgac ctcttgtagc tgtcttcaag
    12301 cgatttttca agttactaag ttccatgcgt gttggtttaa catttaatcg tgccattgat
    12361 ataactcctt tcgtcaaggg cttgaaattg catggtcaac tcaatcattt gcaacaaaaa
    12421 cctttgtcat cgtggtatct gctttaggca aataacgatc taacatatca tctttaatgc
    12481 gttttaattc ggtacgtggc aaaatcgaca acaattccca acccaagtca agactttctt
    12541 caatgctacg gttggtgtaa aatccttggt taatgtattc ttcttcaaac cggttggtaa
    12601 aggccacata tagtttatcc gtttcagaaa gggctgattc accgagcaca acagccaatt
    12661 ccttagcttg ttttccttgg gcataggctg caaagagctg attcattgtg gcagcatggt
    12721 cttgtcgagt cttaccttca cctgagcctt tatcttttag gcgagatagc gatggcaaga
    12781 cattaatagg cggtctaaaa ccatttttat atagttcttg cgacaaaata atctgacctt
    12841 cggtaatata acctgtcaaa tcggggatag ggtgggtaat gtcatcttct ggcatggtta
    12901 aaataggaat ttgagtcact gacccttttt tcccgatcaa gcgaccagcc cgttcatata
    12961 aggtggagag attagtatag agatagccag gataacctcg tctgcctgga acttctctgc
    13021 gagcggctga tacttctcgt aaggcttcac aataatttgt catatctgtc atgatgacta
    13081 aaacatgcat acctttttca taagccaagt attcggctgt tgtcagagct atacgtggtg
    13141 ttgcaatgcg ttcaatagca gggtcattag ctaaattgat aaataaaaca gatcgatcaa
    13201 tggcacccgt ttcacgcaag tcattcataa agaattctgc ctcttcaaaa gtaataccca
    13261 tagctgcaaa cacaaccgca aagttatcat cagagtttag aacagttgcc tgacgagcaa
    13321 tctgtgcggc caattcatta tgaggtaacc ctgagcccga aaaaactggt aacttttgac
    13381 cacgaacgag ggtattgagg tgatcaatag ctgagatacc tgtctggata aattcgtctg
    13441 ggtaatcacg agcgacagga ttgatcgctt gaccatcaat atcaaggtat ttttcgggaa
    13501 taagttctgg accgccgtct atgggctgcc ccattccatc aaagatgcgc cctaccatat
    13561 cttctgatac ggctaattcc aaaggatgcc ctgtaaatcg aaccttggtt ttggctaggt
    13621 tgatgccagt tgatccttca aatagctgta ccatagcctt gtcaccttgg acttctaaga
    13681 cttgaccttt acgcctttct ccattatgca aagtaatatc taccaattcg ttgtagtgca
    13741 ctcctgcaac ttgatcaaca atcatcaaag ggccaaccac ttcgctaacc gtccgatatt
    13801 ctttgagaac gctcatctaa attcctccct ttgctaaaac gtggtgaatc tctttggtaa
    13861 ccttctgagt aagcccttta atctgctcta agttttcttc tgggataaat ttgctgcgtg
    13921 cgatgcgatc gcgtacctga gcagtgcctt ccataatctc attaaaataa gctcccaaag
    13981 aaagggcttt gccggcttcc tcattaaagg tcaaaatatt ggttagcatg gcctcttgtt
    14041 tcggaaagga agtaaaggta tccaccgaat caaaggcatt ttgctggaga taatcctccc
    14101 gaatttgccg ggcaacagcc atggtcaaac gatcttgttc agacagtgaa tcaagcccca
    14161 ccaagcgtac aatttcttct agactggctt cacgctgcaa aatagccatg gcacgagtta
    14221 ccttgttgga ccaattagat tgctgtttac ggtcaatata gcttcctaca tcatcttgat
    14281 acaatgaata agacgtcagc cagttaatcg ctgggaagtg acgccgttgc gcaagaggcg
    14341 cgtcgagccc ccagaaaact ttgacaatcc gaagggtgtt ttgagtgaca ggctctgaaa
    14401 tatcccctcc gggaggagaa accgcaccga tggctgtaat ggttccctca cgttcttgac
    14461 ttcccaaggt ccgaacacga ccagcccgtt cataatattc ggcaatgcga ctccctaagt
    14521 aagccgggta gccttcatca ccaggcattt cttgtaggcg tcctgacatc tcgcgcagag
    14581 cttctgccca acgtgatgtc gagtctgcca tgatagccac agaatagccc atatcacgga
    14641 aatattcggc aatggtaatg cctgtgtaaa tcgacgcttc acgcgctgct actggcatat
    14701 tagaggtgtt tgcaattaac accgtgcgct ccataatgga ctggcctgta tttgggtcaa
    14761 ttaactctgg aaactcattc aaaacgtcgg tcatctcgtt gccgcgttcc ccacaaccga
    14821 cataaataac aatatcaacg ttggcaaatt tagctatttg atgctgcaca actgtttttc
    14881 ctgccccaaa tggtccagga acggcagcgg caccaccttt tgtaacaggg aaaaaggtgt
    14941 caataacccg ttgacctgta accaaaggct cgactgggat aagcttttga gcaacagggc
    15001 gactttgacg aactggccaa gtctgcatga ggctaccttg gtaaatggaa ccgtcttcct
    15061 gcttaatttc ataaactgta tctgttactg tgaagtcccc tgcatgaata gccaccaagg
    15121 tccctgaaac tttataagga accatgatac ggtgctcaat gacagctgtt tcttgcacag
    15181 ttcctaaaat atcacctgca actacttctt gaccaacact tagcttggga ataaatgccc
    15241 acttagcctt tcgatcaaga cttgggatag ccacaccacg gattaaaaag tcgctgtccg
    15301 ttgctttttg aaaacgatca agcggtcgct gaataccgtc aaacatttct gaaatcaggc
    15361 ctgggcctaa ctcgaccgac aaaggacaac cagtagtcac tactggttct cctggaccaa
    15421 tccctgatgt ttcctcataa acctgaatag atgcttgatc gcggcgcatt tcaataattt
    15481 ctccgactaa gccaagatgt cccacacgac aaatatcttg aatattagct tcttgcatcc
    15541 cagaagccat aacaagaggt cccgaaacgg ttattatttt tccttggttc acctttttcc
    15601 tcctttattt tttccaaatc atactaacta atctatactg tcaaggttta atgtgactat
    15661 tttgaatagt cagcaaacta tcctatgcgt tcagctgcta acttcaccaa ttttcctgtc
    15721 cttgcatttc atcagttagc tactcataag cctcaaacag agtataagtc ctctttgcct
    15781 aacgtcttag tgttataaaa tattttgacc gacagccttt tcaaccatgg cttgtatacg
    15841 tgacaggcct atcccttgcg ctccttgatg agttggtaat ggtatgactg ctggtagaac
    15901 ttgattgtca tagtgagtga gggcttctgg aatagctgca gcaatatctt ctgtgatata
    15961 aataatacca aagtcttcca ttgctagttg acgcaactgg ttaatagcgt cttgtggttt
    16021 tattactgga aaagtttgaa acccaatcat ctgaaaaggt aaaataacat ctctgttacc
    16081 aattaccccg actttataca atgttttggt catgctattg gtctcatcct ttctatgaca
    16141 cgttctttgg gtaaatcatt agctaaagca gccgctaaaa gccgtaggtt ttttacttca
    16201 aacgatttag cgagcaaaaa gcgagcaagc acataaggcc catcgacttg atatttggcc
    16261 ttcgcaaata aatggtaaag gcattcatca acaaggtatt ctaactcagt cgtttgaaga
    16321 gtgccttggc gaagtttctc tgaataaggt tttagggctg tcatatagct atcaggtgtt
    16381 acattttcaa accacgtcat cagatcctta tcatcttcaa gtgtgataaa tgttttactt
    16441 ggcctacttg cttcatcaga taataactgc atcatgaaac ttattggttt attttgcgac
    16501 ttggcccgtc tgacggtaat cagattatac aaatcaatca caataagaac agcttgttgg
    16561 aaaacagggt cctctaatct ttgtgctatt tgtttcaacg ccttaaaata agctaagtca
    16621 gtaccaattt ctaagacgcg tatgtcttga taatcttgat attcggccca aatggactgg
    16681 atttctgtta ccacctcttt tggaaactca tcagaagtca tcgtcctaat caaatgttcc
    16741 aaagccacca aaggcttgtc accaattggt agtaataagt gactcagatc tgcttgacta
    16801 gctttagctt ttaacaacac tttgacatta tgataggtgt aacgcaaggt aaataattgt
    16861 actatgtcag gttgaggggt ttctgcaaaa gcccagcgat aggtcttggt tagctcagcc
    16921 attaagatag attctagccg atccaaatcg ttgagatcgt caacagttag gtgatagact
    16981 gactggtgca acagtcgagc taaggttgtt gtattgggag cctgcaatag cttatcaaat
    17041 tgctctttag tcaataactc tttttcttta acactgatag tagtgtttaa ttctagaaat
    17101 gttggcatcg ctagtcaaac ctcctatatc tctgaaaaaa gcatatcaat gatgcgggag
    17161 ctttcttctt taagaactga ttctaaaagg taacggtata aataattgtc atcgacttgg
    17221 tctaaactga ctaaaaatcc tgcttcctga ggaattagct cttgattata gcttaattga
    17281 ggaaatgcta atctcagctc agcacaatca taagaactaa acttttgccc tgttttttcg
    17341 ccaaaagtaa cttgcaatgg ctgttctgga tatttagaca agacttgctt caaaaaagcc
    17401 aattcttctt ccttagaaaa gttcgtcatc ttctccaaag aagcttcaaa tagctccttt
    17461 atactgtctt gttttaatgc tagtagagct tgtctttctt ggtttttgag ttgctgctgc
    17521 gcaacctgaa attgctgttc aagagctttt aactcttttt gacgctttgc ttttaaatcg
    17581 tgtagtcctt gctgttgacg ctctttaaag tcagtatcaa gactatctgt cgctatcttt
    17641 aggcactgtt gaccttcttg atgtgctttt tcaagaacat tttgtcttaa ctgtgttata
    17701 tcattcacct aatttccccc ttttgatagt gttagtggta ccaccatttt ttaaaatcta
    17761 gataaggacc ataccttatc caattttatt taagagaata aaggagacga caaaggcaag
    17821 aatagcatag gtttcaacca tagctgctaa aatgacaccc ttcataaaat ctttagggcg
    17881 cttagccaag atttgcatac cagctacaga aacattgcct tggtgcttgg ccgaaaaata
    17941 accaacaata gcaattggaa gagataccaa aaagtaagct aatccttggt taactgaaag
    18001 ttctggtgtc agtttcatcc aaattaaaat accaatagca aagccgtaga ttccttgact
    18061 accgggtaac agttgcaaga taagcgcaga cgtaaatttt tcgggttctt cttttaagag
    18121 tgcagctgcc gcttgaccac ctttaccgac accataagct gagcccatgc cactaagagc
    18181 tacggctaaa acaattccta aggctgcgaa gaaaacgcca ccatgtgctg taaaataatg
    18241 tgctaaatgt tccatgttaa ttgtcctcca aatctgtttc ttcattgaca ttgacataat
    18301 tatcagctaa ctttaaagga ttgaaagctt ttcctccacc ttcataaaat tttccaaaaa
    18361 actctacgaa aataagacga gcaccatgca catatcctga aagcattgat aagaaaatat
    18421 tgatcgcatg caaaagaata aaaataaaga tacctactgt aaagcgcgtg actggtggaa
    18481 aaatcccaac aatcatgtta aaagccgctc caatactagc tccagaaagc cctaatgcca
    18541 ttagacgagt aaagctaacc aaatcactta agtaagagct aatgccatat aaattatata
    18601 atccactacc tagacctaaa aggcttttgc tttttagtaa agaaacaacc aaaatcccaa
    18661 aggcattgcc caatgcaagc cacttaccaa taaccgataa gtaagcaagg ccagatacat
    18721 tcttaccaag aataaataac agcaggccta ataaaataaa agtccaagct agacttgacg
    18781 tataggccgt agcatatgct ttcatcctta cttgttgcca tgctcctaac aaaagcccaa
    18841 atataagtgt aacaaaccca aatagcaaag aaacaaccaa aatagtaatc acatccgttt
    18901 tagttgataa taatgccaca ggtaagtcaa aaccaaagaa agaaccgtaa ataagccccc
    18961 atatggctac tgaaatagct aaaatattaa agaaggtcac taaccgttta ctggtttttt
    19021 ggagattaaa aaagaccaat gcagctagtg tcacagcata tagcaacaaa ccatagccca
    19081 aatcagctac catcatgcca aaaaaagtaa ggtataaagg agctaaaaaa ggtgtcggat
    19141 ctttttcttg atattttggc aaggcgtaca tttctgtaac caattcaaac ggtgcaatgt
    19201 agcggtgatt acgtagctta atgggaacat cttcccaatc gtctggcgtg acatcgtaac
    19261 tatccagata aaacatatca cctagtgtct tagtcattag cccttttaat tggttaaccg
    19321 aatcagcttc tatccaccct tctaaggcta ttagatgtct tgtaccgagt aattgctttt
    19381 tagtttgctg ccgttgatac tgactaagga catagtctat ttcaacctgt aactgtgcca
    19441 gtatcttttg agactgccta agctctttta gtagactatc tttttcagct agccaattcg
    19501 ttagtaactc tttgtttata cgaagttgtt ctgatggcag tagctgttct ttatataata
    19561 agggtttaaa ctgatatttc tgtaaatgaa tcgtatcttg tgcttgccaa aataagacaa
    19621 ggccgtactc aaattctgta tggtatactt cctcaataaa aagacctttg tgctgcttta
    19681 gctgatgata aaaatgatca tttgctgtac taggaatcgt tccaactctt gccgacaaaa
    19741 aatgaaattg cgctaagtcc tgaggcaaaa cagtcaagga acgccacttt tctaactcct
    19801 gacagtattc tgttagctgg tctattttgt tttgcagctg ctctagtcgt tctatctttt
    19861 gtgacatcat tttcaaagcc gtttgagatg cttgttgtcg atggcgttct tcgaactgtt
    19921 taaacgaaag agatggcgtt ttttgtctca aggctgttaa ctttcctatt ggtggtaaaa
    19981 acgctgataa gctagcaagg ccgttttcta actcttgttg gctttgtaaa aggtattgta
    20041 aagcttcatc atctagtaga ggtttttgat gcgtcagatc gtattggacg atttgtggca
    20101 acttgacgtt gcctttgtta aaagcatctt gccaatgttt tagttgcttc atgtcacgaa
    20161 cttcaactaa ttgagattgt tgaagtgttt ttaaaacaag atcaagataa tctttttcaa
    20221 aaaccattgc cagctttttc atttgactaa tggccatatg tctccaccac cttatccact
    20281 aactccctaa caacggttag cttatgctct tctaaaatgg catgaagggc tagctgttgc
    20341 gtcgctaacc tcttttttga agctttttgt tcttgacgat tagcttcaaa aaacacctca
    20401 cgtttagctt ctaatagtag ctgagtttct tgttcgtact caaggaacag ctgctttaac
    20461 tcttcttctt ttttgtcagc tagagctttt ttcttagcat cgtaactgtc ataaattgtt
    20521 ctagcctctt gttcgatact attcattagt gacaataggg tattcatcac atatcaactc
    20581 cttatcttta tctattgcta attctttgac tcactaggta cttaaaaaca aagctacaag
    20641 aaaggctact tttgggggtt aatcaaccag cgactataag ctagagctaa atctctaacc
    20701 tatctactaa cagctttttt gagataggat aattgcttga ttaagcgaac agcatcttca
    20761 ggttaagcgc tttcaattct atccataaaa acaatggctt agttcagaaa aaggttagct
    20821 aaaaacctgt caaagcagta agatgacaca gaactctaaa gctttgtatt gctgtctttc
    20881 gtgtattatc ttatacttct ttaggcattt agtaaccttg atctagttga cggtaaggaa
    20941 cctttaccag ccaatagcca agccaatgtg ataacagtat aactgctatc gtgttaaaag
    21001 tcctgtcaaa aagatgttta ttagtttctc gcttgtaatt cttgttttgt tactaaacgg
    21061 taatttttaa agacagaacc tccaatataa cccacaatta agctgataat aatacatcca
    21121 agggctgtta tcaacacttt agcgacagga ttataggcaa acatcaccgc aaaaccggca
    21181 atcggagtag ctgttcctgg cgtatcatta accaatttca ttagggcgat caaaacacca
    21241 catgcagcac caccaacaaa attagtcaca taaatcggaa tgggattggc tgacgtcaca
    21301 tctgcctgag tcaacggttc aatagcaaaa gcaatattgt cttttctttc acccaatttt
    21361 aatcggtaaa aaagaacacc attcataaaa gaagagccaa agacagataa ggcacctata
    21421 gccatcggaa tacctgtcag accaagcatg gctgtcaaag ccattgatga cagcggagct
    21481 gttgctacaa caacaatcgt accgcctagt atcattccca tgataatagg gttgctatta
    21541 gcacttgagg tcaggatgtc tccaatagtc aataaagtac tattgatcac tggcgtaatt
    21601 aactgcgcca agaaacgagt taatggtgca ccgacaataa taatcgagat taaatcaagc
    21661 ccaccaggaa tatttttttc catccacttg attaaaaaag ataccacata cccagccaca
    21721 aaacctggga taatacctgt tcctgaaact gacaaaccaa tcaaaacggc ataacctgga
    21781 gacacaccaa ttgcaatggc aaccaagata gcagcagcta cccctgataa tgagccattt
    21841 gctccgccta cttcacttag aaactgaaag cctaaaacct taccaaaaaa agaatcttga
    21901 aaggcttcaa ctaaaaaaga ggcacaagct gccgaagcca aagctcccat tgccttggca
    21961 ccatgaggag ccttatagtt aaacaagcta aaaatagcta aaacaagaat caaaagactt
    22021 gttccaataa taatatccat aatctattcc accaatctat ctcattacat aagacactat
    22081 aactgcttca ctctggcgac agcttcgact tcaatcaaag cttgcaaagg aagcgccgat
    22141 acttgaaccg ctgtccgaac agggtaaggc tcttcaaaca aatcagtcat gacatgattt
    22201 aatatttcca cattggtcac atctgttaaa tacacattta gcttatagat atgattcaag
    22261 tccaactttt gctctgccaa aatagattgt aaattaacaa aaacctggcg acactgtgcc
    22321 tcaaaaccat ctgacaattg acctgtcact ggattaaggg gtaattggcc tgcggtgtat
    22381 agaaaatgtc cttcaatcgt ataagttgaa taagggccca ttggttctgg gtagctcttc
    22441 atatacgaac ctcctcattg ataatatagt taaattttac aggaaaccgc attcacagtc
    22501 aataataaat tctctttttg ataaaaaatt attattaagg tgactggcaa ttgtttttta
    22561 gtctaaaatg tattactata tttgtaaata agaagataga tataggaggt ttgacatgga
    22621 taaagaaacg ctaaactact ggaaaacggt tatcacattt cttcacgatg tcttaggtga
    22681 taactatgaa attattttac atgtgattga taaaaatgat atctatattg gagaactcgt
    22741 taatagtcat atcagtggac ggtctaaaca gtctcctctc accacctttg ctcttgattt
    22801 gattaccaat aaagtctata aggaaaaaga ttttgtgacc aattacaaag caatcgttag
    22861 tcctcagcac aaagaagttc ggggatctac tttttttatt aaagataaaa agggtaatct
    22921 cgagggaatg ctatgtatta acttagatat ttcagcctat caaggagtag ctagggacct
    22981 cttaaaactt gtcaatctca atttagaaca tttcatccca actgctaaag aacctaaaac
    23041 agtcacaccc cagccagaag aagctgttga aattttaacc tctaacatcc aagatattat
    23101 cggtcaaatt attgatccct cgttactgag acacaatgta catcttagcc aagatgtcaa
    23161 aatagacatt gttgccaagc tttatgaaaa aggagtcttt caactaaaag gagccgtctc
    23221 aaaagtcgct gatattctat gtatttccga accaagtgtt taccgctacc ttaaaaaaat
    23281 tgaagccgat caataactaa atcaccataa aacgccagtt aaaagtattt cagataagca
    23341 tcacaatctc tgatataccg atgactgacg ttttttttac tcaatatgcc tttatggcaa
    23401 gaaaaggcta ctagtcatta accttcagct atgcttagag gtacacctgt cgcagcttga
    23461 acctcatcaa aagtaaaccc ttcactgatt tcaattactt ggataccatc tggcgttact
    23521 ttaaacacac ccatttctgt gataataagg tcaaccacac cttttgctgt taaaggtaag
    23581 gtacattctt ttaggagctt atgctttcct ttattggtat gctccatagc tacgatgact
    23641 tttttagcac caactaataa atccatcgct cctcccatac caggaaccat tttgcctgga
    23701 atcaggtaat tggcgatatc tccattttct gcaatttcta aagcacccaa gacagtcaag
    23761 tcaacatgac caccacgtat aatgccaaaa gaatctgcac tattaaagaa agcggctcct
    23821 ggataaaccg tcacaggctg tcctcctgca ttaacgatag tcgaattcgg atcatctgac
    23881 ttaggaccta gtccaataaa cccattttca gattgaaaat acactgtcat ttcttcaggc
    23941 acaaaatttg ctactttggt tggtagacca atacctaaat ttaccaaagt accatcttct
    24001 aattctttgg ccacacgctt tgcaatacga ttttgaatct cttctttact taatgcaacc
    24061 gccataacta tactccttct ttaacaatgt aatctacaaa aatgtgtggt gtatgaacgc
    24121 attctggttg tatggtgccg actggtacta tttctcgcgc ctgaacaatt gttgtttttg
    24181 cacaagctgc catcaattga ttaaaattat tttcagaacc actatactgt aaatttccca
    24241 tttcatcagc ttgattagca aatatcaagg cgacatctgc ctcaaatggg tattctaaga
    24301 gataggtttt tcccttgatg gtttttgttt ccttgccttc tgccactaag gttcctaccc
    24361 ctgttggcgt gtaaaagcca ccaatgccat aagctccgat gcgaattttt tcggcgaagg
    24421 ttccttgagg aatgagctca atcgtcgttt caccggcagt catttggcgc ccagcttctt
    24481 tatttaatcc aatatgtgtt gcatagatgg ttttgaattg atgattagcc accatttttc
    24541 caacaccgcg atcaacaaaa ccagcatcat tacagatcaa ggttaagtct tttgtgcctt
    24601 tgtcaaccag tgcatcaatt aacgcttctg gtgttccatt agccataaaa ccaccgacca
    24661 taatcgtgtc accatcttta atatgactga tagcttctgc tattgctatt cttttattct
    24721 ctttcatacg gttaccttct atcttgttac gatgatactt tgaccttggc caccaccaat
    24781 acaaagcgtt gctaagccat gtctcacatc acgcttagcc atttctgcta ataaggtgac
    24841 taaaatacga gcacctgatg ctccaatcgg gtgacccaaa gcaatagctc ctccattgac
    24901 attaactttt tcattgtcaa aaccaaggtc tcgtgaaacc gctaaagcct gagcagcaaa
    24961 agcttcgttt gcttcaatca aatcaatgtc atcaattgtc agctgagcct ttgcaagagc
    25021 ctttttcgta gcaggtattg gtccgcagcc cataatactt gggtctacac ctgcacttgc
    25081 ataactagtg attttagcta aaatagggag ccctaattct tcagcttttt ctttactcat
    25141 caataaaatt gccgctgctc catcattgat tcctgaagca ttaccagcag ttactgtccc
    25201 ctcatctttg ataaaagcag ggcgtaactt tgctaactta tccactgtcg ttccaaattt
    25261 agggtattca tcttgatcaa cgagtaaagg ttcaccttta cgctgaggaa tagtgacagg
    25321 tgcaatctct tctttgaaac gacctttttc tatggcaagt tgggctttac gttggctatc
    25381 agctgcaaag gcatcttgtt cttctctggt cagtccatac tgttgcacaa tattttcggc
    25441 tgttataccc atgtgataac ctgcaaaagc atcactcaac ccatctttaa gcagggtatc
    25501 tactacttta ctatctccca tacgagatcc ccaacgttgg ccttgtaaaa cgtaaggtgc
    25561 ttgactcatg ttttcggtac caccaactaa aacaatatca gcgttgcccg tttgaatctt
    25621 ttgagcacct aactcaactg cttttaagcc agaaccacag accatatcaa tcgtaaaagc
    25681 aggggtatca taagaaagcc ccgcatttag cgctacttgc cgggcaacat tttgacccag
    25741 acctgcatgt aacacattcc caaagatcac ttcatcaatg gcatcacttt taagaccggt
    25801 atcagctaaa atttttgtaa caactgtcac ccccaaatct acggctgata aagatttaaa
    25861 gactcctcca aaatttccta tcggggtacg ataagcagat gtgatcacca cttctttagt
    25921 catagaaact tctccttttt cattattgaa acgcttacat ttttattata taatgtgaac
    25981 tataataaac aaatatcgtt tttttatata tgctataact aaacgttatc gaaagaggaa
    26041 aatatgaata tctcaagctt ggcttatttt attgagattg ttaattgtga ctttaactta
    26101 accaaagcag cccaaaaaag tcatatttcg caacccgccc ttagtagtta tatcaagact
    26161 atcgaaaaag aagaaggagt cgttttattc cagcgtcaaa aagggcgtct agttggacta
    26221 acctcagtcg gcgaacgctt ttttgaaaat gctaaggtgg ttatcgcatc acatgagcaa
    26281 ttaatggctg atttgcggag tgaatccaaa aaatacaaag gagaaatttc aatcggtatt
    26341 cctcaactca tctctggcat tgttttttct gagctcattc caaaactcat cgaagaaaat
    26401 cccgaagtta aatttcatat tgtagaaacg ggtgcttatg aactgcaaaa aaaactgttt
    26461 ctaaaagaag tcgattttgc gattttatta acacccacta cactagatgc tactattgct
    26521 gatatcgaca ttctcctaag agatcaactc tgcctttata tgagtcacaa aacctttcaa
    26581 gagacgtttg atagtaatcc taacatctct atcaaagcat tacatcgtca aaacttagta
    26641 acttttgata aaacctttat gattaatcat cagcttacca ccttatttga agaagcaaat
    26701 agtcttcctg tagtcaaatg ttattctgcc tcgtgggatt ttttattaaa ttgcacgcgc
    26761 tattcctctt acctaacaat cctaccaaga cctattactc attttgctca tatggacggt
    26821 ttagtggagg tccaactgac cgaacatcca aaatgggaag ttgttctagc ctctctcaag
    26881 cacaataaaa caagccattt aaaacattat atcaagcaca ccatcttaga ttatttcacg
    26941 aaccagcgct tctaattgct tgactcagac cttaaaaaaa aaaacgcctg aaggaaacaa
    27001 tcccaagcgt ttcatatagt tatttcctaa aatacaaata ggtaaatgat ggcaatacct
    27061 gtgaccacca agacacaagg aatagtataa gccacaattt gattgaattt tagtttgaag
    27121 tttgagaggt aagataaggc ccaaaaagga actatcaagt ttgttgtggc atctcctaat
    27181 tgatacgcct gcaaaatctt acctaggtca ttaccaactt cgatggttgc agggacgata
    27241 tagggagctt caatcacaaa ttttgagcct cctgatggta ccgcaatatt cagcaaagcc
    27301 gagtaaagat aagcaaagac cggccatgtt gtcccatttg aaatagcgac aaagaaatgg
    27361 gaaatctcta gtcctagacc tgtactttga atgattccaa aaataccagc gtaaaatgga
    27421 aactggagca ccaagcccca agatgacatg accccgtctt tgaataagga accataatat
    27481 tctggtcctt gttgaccaca aagaagcaac cctaagccta aaaataaaaa gttaaaacta
    27541 ttgagatcta gaccagacaa gcccaccacc gaaaaatgat aaaggctata gctaacaatg
    27601 gccccaccaa caagatacat cactaagcga gatgcgttca tcttctcagc aggtgtgttt
    27661 cttgcaataa caacatgtga agcggtatca agactatggt gatagatctc atcatcaagt
    27721 tccatgattt tagtttcatc ttttgggtgc gccaataaag caaagcaaag cggtaccagc
    27781 atacacacca ctaaaagact gataaatgga agattcaaaa ctgattctgt cagaggaaca
    27841 ctttcaggaa caacctgttt ataagcatct gcgacactat ttcgcaaata atctggagta
    27901 gccgaataaa gcaccgcagc accagataaa ccagaagtag ctggtaaaaa ggtaaaaaat
    27961 aaagtagcaa caaacaaagg tgtatgcacc ttaatccctt tttgcctagc ctgaacaagc
    28021 aactctttcc caaacacaat ggcaaccatc ataccaagac cccagtgtaa aaaaccaaag
    28081 atagagccta ctacaataga aaaaataaaa atctgagtcc tggtttgagg cagtttggca
    28141 agggacttaa acattttatg agcaggtgga gaactcgcta cagcattccc tgtcgcaagt
    28201 aaaatagtca tctgcatggc aaaggacaac agcccccaaa aaccatttac ccagccatag
    28261 ataatcccgc ccgtcttttc cgtaccaata aagggactat ccgtcatcaa cacagacata
    28321 gtaacgacta aaaaggttaa aataaaacag ataaaaagcg attctggcat ccatttcata
    28381 aagccatcaa tatagcgatc cataaacctt tttttggttt tgctgttatt catgttgtca
    28441 attcctttca cattgtccac aagcactttt gttcttttga tcagtaacct atcgataata
    28501 ttaataagcg tttctttagt tcatttagtt atcaataagt ttaaacccac aaaaaacact
    28561 tttgttccct ttttattatg acaacgtttt cataaacaaa caactatgat tttttta
//
LOCUS       DAUGSW010000019        27650 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUGSW010000019 DAUGSW010000000
VERSION     DAUGSW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27650
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.019"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            125..4231
                     /gene="cas9"
                     /locus_tag="VIB18_001005"
     CDS             125..4231
                     /gene="cas9"
                     /locus_tag="VIB18_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEQ8766022.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENLINASRVDAKAILSARLSK
                     SRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSDILKE
                     YPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLGGD"
     gene            4231..5079
                     /gene="cas1"
                     /locus_tag="VIB18_001006"
     CDS             4231..5079
                     /gene="cas1"
                     /locus_tag="VIB18_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8766023.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSEIVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCITQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTFNGKEMYLTNIISDYTKKVVKALNNEGKG
                     VPEFRI"
     gene            5076..5417
                     /gene="cas2"
                     /locus_tag="VIB18_001007"
     CDS             5076..5417
                     /gene="cas2"
                     /locus_tag="VIB18_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8766024.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKVYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5407..6069
                     /gene="csn2"
                     /locus_tag="VIB18_001008"
     CDS             5407..6069
                     /gene="csn2"
                     /locus_tag="VIB18_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEQ8766025.1"
                     /translation="MNLNFSLLDEPLPLRGGTILVLEDVCVFSKIVQYCYKYEEDSEL
                     KFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
     repeat_region   6172..6537
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6172..6207
                     /rpt_unit_seq="gttttagagctatgctgttttgaatggtcccaaaac"
     gene            6665..7054
                     /locus_tag="VIB18_001009"
                     /pseudo
     CDS             6665..7054
                     /locus_tag="VIB18_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            7178..9010
                     /gene="lepA"
                     /locus_tag="VIB18_001010"
     CDS             7178..9010
                     /gene="lepA"
                     /locus_tag="VIB18_001010"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEQ8766026.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK"
     gene            9198..10193
                     /locus_tag="VIB18_001011"
     CDS             9198..10193
                     /locus_tag="VIB18_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8766027.1"
                     /translation="MNKTKQNKTKQNKTKHSLLCRYGLTSAAALLLTFGGASAVKADS
                     QGIRETQEALQGVRSKFPKLTKYIPNDNISDKTPIYQYLQELERNLDSYLSILDERMD
                     HLKGDRGETGPAGPAGKDGEPGEQGPMGPAGARGPEGPMGPRGEQGAPGAKGDRGETG
                     PAGPVGKDGERGPVGPAGKDGQDGLPGKDGKDGQDGKDGLPGKDGKDGQDGLPGKDGK
                     DGQDGKDGLPGKPAPKTPEAPQKPDTAPDTPKTPQIPGQSKDVTPAPQNPSNRGLNKP
                     QTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN"
     gene            10379..10816
                     /gene="msrB"
                     /locus_tag="VIB18_001012"
     CDS             10379..10816
                     /gene="msrB"
                     /locus_tag="VIB18_001012"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8766028.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            10946..11965
                     /locus_tag="VIB18_001013"
     CDS             10946..11965
                     /locus_tag="VIB18_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEQ8766029.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSFPIIISTIATALL
                     VAYGLQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVS
                     ADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            12172..12597
                     /locus_tag="VIB18_001014"
     CDS             12172..12597
                     /locus_tag="VIB18_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8766030.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            12616..13107
                     /locus_tag="VIB18_001015"
     CDS             12616..13107
                     /locus_tag="VIB18_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8766031.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            13124..13933
                     /locus_tag="VIB18_001016"
     CDS             13124..13933
                     /locus_tag="VIB18_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8766032.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAINKQTTFDSKESEEEDFFA"
     gene            13930..14757
                     /locus_tag="VIB18_001017"
     CDS             13930..14757
                     /locus_tag="VIB18_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8766033.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLLVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            14893..16542
                     /locus_tag="VIB18_001018"
     CDS             14893..16542
                     /locus_tag="VIB18_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8766034.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPNQGLLFASNPHLGNTFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSKYLHHYFVFQDNRAFITRKVSLQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            16546..17331
                     /locus_tag="VIB18_001019"
     CDS             16546..17331
                     /locus_tag="VIB18_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8766035.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDTLVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSMS"
     gene            17328..18374
                     /locus_tag="VIB18_001020"
     CDS             17328..18374
                     /locus_tag="VIB18_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8766036.1"
                     /translation="MTKLKGKWFIGLLCLVILALSGGALALKTLSSKQQMPKELVILS
                     PNSQTILTSTIPAFEEKYGIKVRLIQGGTGQLIDQLRQKNKQLKADIFFGGNYTQFES
                     HKDLFKSYVSPQVATVISDYQLPSHRATPYTINGSVLIVNNELAQGLTITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTNADAWAYMKRLLVNMNSIRATSSSEV
                     YQSVAEGKMIVGLTYEDPCINLQKSGANVSIVYPKEGTVFVPSSVAIIKHAPNMTEAK
                     LFINFMLSRDVQNAFGQSTSNRPIRQDAQTSHDMKALETIATLKEDYAYVTKHKKKIV
                     ATYNLLRQRLEKAK"
     gene            18471..18976
                     /locus_tag="VIB18_001021"
                     /pseudo
     CDS             18471..18976
                     /locus_tag="VIB18_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            19153..19719
                     /locus_tag="VIB18_001022"
     CDS             19153..19719
                     /locus_tag="VIB18_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEQ8766037.1"
                     /translation="MTTEFDKMTRGEWYDANFDSELIQKRMMAQDLCFDLNQLKPSRE
                     EERSAVLNQLFGQSFEGLVLLSPFICDYGKNITFGKNCFINSNCYFMDGAKIALGDNV
                     FVGPSTGFYTANHPLDYKRRNEGLEKALPITIGDNVWFGASVNVMPGVTIGSGCVIAS
                     GSVVTHDIPVNSLAAGVPCQVVREIEQE"
     gene            19735..20424
                     /locus_tag="VIB18_001023"
     CDS             19735..20424
                     /locus_tag="VIB18_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEQ8766038.1"
                     /translation="MHYNFLFFDLDHTLLDFDAAEEVALTKLLEEYQVIDIKAYKDYY
                     KPMNQNLWKQLEGGDTSKADLVNSRFALLFAHFGVTVDGRQLAEGYQKHLKDQGQVYA
                     GAKELLADLTAQGYNLYAATNGIATIQQGRLQASGLAPYFKAIFISEQSGSQKPKKAF
                     YDWMTQQVSHYQPDQALMIGDSLSADVQGGINAGMDTLWYNPKHLLNNSPVHPTYEVS
                     DYQALLNCIAE"
     gene            20519..21916
                     /locus_tag="VIB18_001024"
     CDS             20519..21916
                     /locus_tag="VIB18_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEQ8766039.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQGVADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSMPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            22018..23814
                     /gene="uvrC"
                     /locus_tag="VIB18_001025"
     CDS             22018..23814
                     /gene="uvrC"
                     /locus_tag="VIB18_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEQ8766040.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTESNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDRGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            24001..24603
                     /locus_tag="VIB18_001026"
     CDS             24001..24603
                     /locus_tag="VIB18_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEQ8766041.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            24728..26137
                     /gene="pepV"
                     /locus_tag="VIB18_001027"
     CDS             24728..26137
                     /gene="pepV"
                     /locus_tag="VIB18_001027"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEQ8766042.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDQLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITSPHDLNVLEAALEQFLSEYGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGINGATLLAKFLNQFTFEGAAKYYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGLTKVSLSEHEHTPHYVPIDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(26205..27581)
                     /gene="mnmE"
                     /locus_tag="VIB18_001028"
     CDS             complement(26205..27581)
                     /gene="mnmE"
                     /locus_tag="VIB18_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEQ8766043.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAITQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDWALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
BASE COUNT         8614 a         4908 c         5873 g         8255 t
ORIGIN      
        1 agagatattt tgaaaaagaa aaattaaagc atattaaact aatttcggag gtcattaaaa
       61 ctattagtga aatcatcaaa ctcattatgg atttaattta aactttttat tttaggaggc
      121 aaaaatggat aagaaatact caataggctt agatatcggc acaaatagcg tcggatgggc
      181 ggtgatcact gatgattata aggttccgtc taaaaagttc aaggttctgg gaaatacaga
      241 ccgccacagt atcaaaaaaa atcttatagg ggctctttta tttgacagtg gagagacagc
      301 ggaagcgact cgtctcaaac ggacagctcg tagaaggtat acacgtcgga agaatcgtat
      361 ttgttatcta caggagattt tttcaaatga gatggcgaaa gtagatgata gtttctttca
      421 tcgacttgaa gagtcttttt tggtggaaga agacaagaag catgaacgtc atcctatttt
      481 tggaaatata gtagatgaag ttgcttatca tgagaaatat ccaactatct atcatctgcg
      541 aaaaaaattg gcagattcta ctgataaagc ggatttgcgc ttaatctatt tggccttagc
      601 gcatatgatt aagtttcgtg gtcatttttt gattgaggga gatttaaatc ctgataatag
      661 tgatgtggac aaactattta tccagttggt acaaacctac aatcaattat ttgaagaaaa
      721 ccttattaac gcaagtagag tagatgctaa agcgattctt tctgcacgat tgagtaaatc
      781 aagacgatta gaaaatctca ttgctcagct ccccggtgag aagagaaatg gattgtttgg
      841 gaatctcatt gctttgtcat tgggattgac ccctaatttt aaatcaaatt ttgatttggc
      901 agaagatgct aaattacagc tttcaaaaga tacttacgat gatgatttag ataatttatt
      961 ggcgcaaatt ggagatcaat atgctgattt gtttttggca gccaagaatt tatcagatgc
     1021 tattttactt tcagatatcc taagagtaaa tagtgaaata actaaggctc ccctatcagc
     1081 ttcaatgatt aaacgctacg atgaacatca tcaagacttg actcttttaa aagctttagt
     1141 tcgacaacaa cttccagaaa agtataaaga aatctttttt gatcaatcaa aaaacggata
     1201 tgcaggttat attgatgggg gagctagcca agaagaattt tataaattta tcaaaccaat
     1261 tttagaaaaa atggatggta ctgaggaatt attggcgaaa ctaaatcgtg aagatttgct
     1321 gcgcaagcaa cggacctttg acaacggctc tattccccat caaattcact tgggtgagct
     1381 gcatgctatt ttgagaagac aagaagactt ttatccattt ttaaaagaca atcgtgagaa
     1441 gattgaaaaa atcttgactt ttcgaattcc ttattatgtt ggtccattgg cgcgtggcaa
     1501 tagtcgtttt gcatggatga ctcggaagtc tgaagaaaca attaccccat ggaattttga
     1561 agaagttgtc gataaaggtg cttcagctca atcatttatt gaacgcatga caaactttga
     1621 taaaaatctt ccaaatgaaa aagtactacc aaaacatagt ttgctttatg agtattttac
     1681 ggtttataac gaattgacaa aggtcaaata tgttactgag ggaatgcgaa aaccagcatt
     1741 tctttcaggt gaacagaaga aagccattgt tgatttactc ttcaaaacaa atcgaaaagt
     1801 aaccgttaag caattaaaag aagattattt caaaaaaata gaatgttttg atagtgttga
     1861 aatttcagga gttgaagata gatttaatgc ttcattaggc acctaccatg atttgctaaa
     1921 aattattaaa gataaagatt ttttggataa tgaagaaaat gaagatatct tagaggatat
     1981 tgttttaaca ttgaccttat ttgaagatag ggagatgatt gaggaaagac ttaaaacata
     2041 tgctcacctc tttgatgata aggtaatgaa acagcttaaa cgtcgccgtt atactggttg
     2101 gggacgtttg tctcgaaaat tgattaatgg tattagggat aagcaatctg gcaaaacaat
     2161 attagatttt ttgaaatcag atggttttgc caatcgcaat tttatgcagc tgatccatga
     2221 tgatagtttg acatttaaag aagatattca aaaagcacaa gtgtctggac aaggcgatag
     2281 tttacatgaa catattgcaa atttagctgg tagccctgct attaaaaaag gtattttaca
     2341 gactgtaaaa gttgttgatg aattggtcaa agtaatgggg cggcataagc cagaaaatat
     2401 cgttattgaa atggcacgtg aaaatcagac aactcaaaag ggccagaaaa attcgcgtga
     2461 gcgtatgaaa cgtattgaag aaggaataaa agaactagga agtgatattc taaaggagta
     2521 tcctgttgaa aacactcaat tacaaaatga aaagctctat ctctattatc tccaaaatgg
     2581 aagagacatg tatgtggacc aagaattaga tattaatcgt ttaagtgatt atgatgtcga
     2641 tcacattgtt ccacaaagtt tccttaaaga cgattcaata gacaataagg tcttaacgcg
     2701 ttctgataaa aatcgtggta aatcggataa cgttccaagt gaagaagtag tcaaaaagat
     2761 gaaaaactat tggagacaac ttctaaacgc caagttaatc actcaacgta agtttgataa
     2821 tttaacgaaa gctgaacgtg gaggtttgag tgaacttgat aaagctggtt ttatcaaacg
     2881 ccaattggtt gaaactcgcc aaatcactaa gcatgtggca caaattttgg atagtcgcat
     2941 gaatactaaa tacgatgaaa atgataaact tattcgagag gttaaagtga ttaccttaaa
     3001 atctaaatta gtttctgact tccgaaaaga tttccaattc tataaagtac gtgagattaa
     3061 caattaccat catgcccatg atgcgtatct taatgccgtc gttggaactg ctttgattaa
     3121 gaaatatcca aaacttgaat cggagtttgt ctatggtgat tataaagttt atgatgttcg
     3181 taaaatgatt gctaagtctg agcaggaaat aggcaaagca accgcaaaat atttctttta
     3241 ctctaatatc atgaacttct tcaaaacaga aattacactt gcaaatggag agattcgcaa
     3301 acgccctcta atcgaaacta atggggaaac tggagaaatt gtctgggata aagggcgaga
     3361 ttttgccaca gtgcgcaaag tattgtccat gccccaagtc aatattgtca agaaaacaga
     3421 agtacagaca ggcggattct ccaaggagtc aattttacca aaaagaaatt cggacaagct
     3481 tattgctcgt aaaaaagact gggatccaaa aaaatatggt ggttttgata gtccaacggt
     3541 agcttattca gtcctagtgg ttgctaaggt ggaaaaaggg aaatcgaaga agttaaaatc
     3601 cgttaaagag ttactaggga tcacaattat ggaaagaagt tcctttgaaa aaaatccgat
     3661 tgacttttta gaagctaaag gatataagga agttagaaaa gatttaatca ttaaactacc
     3721 taaatatagt ctttttgagt tagaaaacgg tcgtaaacgg atgctggcta gcgccgggga
     3781 attgcaaaaa ggaaatgagc tggctctgcc aagcaaatat gtgaattttt tatatttagc
     3841 tagtcattat gaaaagttga agggtagtcc agaagataac gaacaaaaac aattgtttgt
     3901 ggagcagcat aagcattatt tagatgagat tattgagcaa atcagtgaat tttctaagcg
     3961 tgttatttta gcagatgcca atttagataa agttcttagt gcatataaca aacatagaga
     4021 caaaccaata cgtgaacaag cagaaaatat tattcattta tttacgttga cgaatcttgg
     4081 agctcccgct gcttttaaat attttgatac aacaattgat cgtaaacgat atacgtctac
     4141 aaaagaagtt ttagatgcca ctcttatcca tcaatccatt actggtcttt atgaaacacg
     4201 cattgatttg agtcagctag gaggtgactg atggctggtt ggcgtactgt tgtggtaaat
     4261 acccactcga aattatccta taagaataat catctgattt ttaaggatgc ctataaaacg
     4321 gagctgatcc atttatcaga aattgatatt ttgttattag aaacgaccga tattgtcttg
     4381 tccactatgc tggtaaaacg gctagtggat gagaatgtcc ttgtcatatt ctgtgatgat
     4441 aaacgattac caacagctat gctgatgcct ttttatggtc gtcatgattc gagtctacag
     4501 cttgggaaac aaatgtcctg gtcagaaata gtcaaatcgc aggtttggac gacgattatt
     4561 gctcaaaaga ttttgaatca atcttgctat ttaggagcat gctcctattt tgaaaaatcc
     4621 caatctatta tggatttata tcatggtttg gaaaattttg atccgagtaa tcgagaaggg
     4681 catgcagcga gaatttattt taatacactt tttgggaacg atttctcaag agatttggag
     4741 catccaatca atgcaggtct ggattatggt tatactttat tattgagtat gtttgcgcgt
     4801 gaagtggttg tgtctggatg tataactcag tttgggctta aacacgctaa tcagtttaat
     4861 cagttcaatt ttgctagcga tattatggaa ccatttaggc ctttagtgga taagattgtt
     4921 tatgaaaatc gaaatcagcc ttttcccaaa ataaagagag agttatttac ttttaatggt
     4981 aaagagatgt atctcacgaa tattattagc gattatacta aaaaagttgt caaagctctg
     5041 aataatgaag ggaaaggagt tcctgaattt aggatatgag ttatagatat atgagaatga
     5101 tacttatgtt tgatatgccg acggacaccg ctgaggaacg aaaagtctat cgaaaatttc
     5161 ggaaattttt acttagtgaa gggtttatca tgcatcaatt ttctatttat agtaagttgc
     5221 tgttgaataa tacagctaac aatgccatga ttggtcggct gagggagcat aatcctaata
     5281 aaggaaatat tacattacta acggtcacgg aaaaacagtt tgcacgaatg atttatttac
     5341 atggtgaaag aaataattgt attgcaaact ccgatgaaag acttgtattt cttggggagg
     5401 cttttgatga atcttaattt ttccttacta gatgaaccgc ttccattaag aggcggtaca
     5461 attcttgtgc tcgaagatgt ctgtgtattt tcaaaaatag tgcaatattg ttacaaatat
     5521 gaggaagatt ctgaacttaa attttttgat cgcaagatga aaaccatcaa agaatcagaa
     5581 atcatgcttg taacagatat tttaggattt gatgttaact cctcaaccat tttaaaattg
     5641 attcatgcag atttagaatc tcaatttaat gagaaacccg aagtgaaatc gatgattgac
     5701 aaattggttg ctacgattac agaactgatt gtctttgaat gcttagaaaa tgaattagat
     5761 ttagagtatg atgaaatcac aatcctggaa ttgattaagt ccttaggagt aaaagtagaa
     5821 acgcaaagtg atactatttt tgaaaaatgt ctagagatac ttcaaatttt caaatatctc
     5881 actaagaaaa agttgcttat ttttgtcaat agcggagctt ttctaacaaa ggatgaagtg
     5941 gctagtttac aagagtatat atcattgaca aatttaacag ttctcttttt agaaccacgt
     6001 gaactatatg attttccgca gtatatttta gatgaagact atttcttaat aactaaaaat
     6061 atggtataat actcttaata aatgcagtaa tacaggggct tttcaagact gaagtctagc
     6121 tgagacaaat agtgcgatta cgaaattttt tagacaaaaa tagtctacga ggttttagag
     6181 ctatgctgtt ttgaatggtc ccaaaacgtg tgcttggctg gcgcatcgca atattaagtt
     6241 ttagagctat gctgttttga atggtcccaa aacgctagcg aagatagagc tagacagaca
     6301 aaggttttag agctatgctg ttttgaatgg tcccaaaacg actaaatttg tcagacaaga
     6361 tacctttgag tttcagagct atgctgtttt gaatggtccc aaaacgtcag actgcccaca
     6421 aataatttta gatgggtttt agagctatgc tgttttgaat ggtcccaaaa ccgagcaata
     6481 ccaaaagcgt tacagctgtg tgttttagag ctatgctgtt ttgaatggtc tccattcaac
     6541 attgccgatg ataacttgag agagggttaa taccagcagt cggatacctt tctattcttt
     6601 ctgttaaagc attttcatgt tataataggc aagagaagag tagtgtgatg gaacaaacat
     6661 ttttatgatt aagccagatg gggttaagca aggggggtta gttggagagg ttttgcggca
     6721 gattgaacgc ctaagactta cgtttgagcg attcgagcta agacaagcta gttcgaaata
     6781 cttggctaag cacgacgagg ccttggtgat aaaccttttg atcctaaact taaagcttac
     6841 atgacaagtg gtcctgtttt aattgggaca cttcttgggg actaaggtgg ttttgtcttt
     6901 ttgaaccatg atgagagtaa ccaatcctac ggatgctctt tgcggaacca ttcgtgggaa
     6961 ttttgctcag gctcctggtg atgatggagg tgtttttaac atggcgtatg ggcctcattc
     7021 aagagactct gctaggcgtg agatcgctct ttgatctcat caaagtaatc atggtagctc
     7081 cgctattctc ttgcaagata atccgtaaga aaagataggc aaaggcctac cttttttgtt
     7141 ataatagaag gaaagactaa atgtatagga aaatagaatg aacagtcaag atttaaaaaa
     7201 acgtcaggag aagattcgta atttctccat tattgcacat attgaccatg gaaaatctac
     7261 tctcgctgac cgcatcttgg aaaagacaga gacggtttcg tctcgtgaaa tgcaggctca
     7321 gttattggac tccatggatt tggagcgtga gcgtgggatc accatcaagt taaacgccat
     7381 tgagcttaat tacacggcta aagatgggga aacctacatt ttccacctta ttgatacccc
     7441 agggcatgtg gactttactt atgaagtatc gcgttcgttg gcagcctgtg agggagcgat
     7501 tctagttgtg gatgcagcgc agggcattga agcgcagaca ttggctaatg tttacctagc
     7561 cctcgacaat gatttggaaa ttttacctgt tatcaataaa attgacttgc ctgctgctga
     7621 ccctgagaga gtccgccatg aagtagaaga tgtgattggg cttgatgctt ctgaggctgt
     7681 tctggcgtca gccaaggctg gtatcgggat cgaagagatt cttgagcaaa ttgttgagaa
     7741 ggttcctgct cctacgggtg atgtggatgc gcctttacaa gccttgattt ttgactctgt
     7801 ttacgatgct tatcgaggcg ttatcctgca agttcggatt gtgaatggta ttgtcaagcc
     7861 tggcgataaa atccagatga tgtcgaatgg aaaaaccttt gatgttacag aagttgggat
     7921 tttcactcct aaggcagttg gacgagattt ccttgcgacg ggagatgttg gttatgttgc
     7981 ggcctctatc aaaacggtag cagatacccg tgtgggggat acggtgactt tagctaataa
     8041 ccctgctaag gaagccttgc atggctacaa gcagatgaac ccgatggtct ttgcagggat
     8101 ttatccgatt gaatcaaata aatacaatga cttgcgtgaa gcgcttgaaa aattacaact
     8161 gaacgatgcc agtttacagt ttgaacccga aacgtcacaa gcgcttggct ttggtttccg
     8221 ttgtggattc ttaggtttgc ttcatatgga tgtgattcaa gaacgtttgg aacgtgagtt
     8281 taacattgat ttgatcatga cagcaccatc tgtagtctac catgttcaca caacagatga
     8341 ggacatgatt gaagtgtcta acccttcaga atttccagac ccaacccggg tggcttttat
     8401 tgaagagcct tatgttaaag cgcaaatcat ggtgccacaa gagttcgtag gggctgttat
     8461 ggaattatcg cagcgcaagc gtggtgattt tgtgaccatg gattacattg atgataaccg
     8521 tgtcaatgtg atttaccaaa tcccgctggc tgaaattgtg tttgatttct ttgataaatt
     8581 gaaatcctca acgcgaggct atgcgagttt tgattatgac atgtcagaat accgcaggtc
     8641 acaattggtg aaaatggaca ttcttttgaa cggtgataag gtcgatgcgc ttagcttcat
     8701 tgttcataaa gaatttgctt atgaacgcgg gaaaattatt gttgagaaat tgaaaaaaat
     8761 cattccacgt caacagtttg aagtgccgat ccaagccgct attggtcaaa aaattgttgc
     8821 gcgttcagac atcaaggccc ttcgtaaaaa cgttttagcg aagtgctatg gcggtgacgt
     8881 gtctcgtaaa cgtaaattgc tcgaaaaaca aaaggctggt aaaaaacgga tgaaggctat
     8941 tggttctgtc gaagtccctc aagaagcctt cttgagtgtg ctttcaatgg atgacgatac
     9001 caagaaataa ccaagcttaa ccgcttagtc ttcagaggag aactcttgtg ggtctacatg
     9061 accaaaaaat tgattatctc ataaaaaaag aactttacaa tctctttcag ataacactat
     9121 aatggtatta tagtgttatc tcattattag gtgagcctac atttaatctt attaaagaga
     9181 aagaggaaac aaaaactgtg aacaaaacaa aacaaaacaa aacaaaacaa aacaaaacaa
     9241 aacatagtct tctttgtcgc tacggcttaa cgtcagcggc tgctcttttg ctgacctttg
     9301 gaggtgcaag tgcagttaag gcggatagcc aaggtatcag agagactcag gaggcgttgc
     9361 agggagtacg tagtaaattt cctaagttga caaaatatat tcctaatgac aatataagcg
     9421 ataagacccc aatttatcaa tatttacaag aacttgaaag aaatttagac agttatctta
     9481 gcatactaga tgaaaggatg gatcatttaa agggtgatcg cggtgaaacc ggccctgcag
     9541 gtcccgccgg aaaagatgga gagcctggag aacagggtcc tatgggtcct gctggcgcac
     9601 gaggtcctga aggtccaatg ggtccacgtg gtgaacaagg tgcgccaggt gccaaaggtg
     9661 accgtggcga aaccggccct gcaggtcctg tcggaaaaga tggtgaacgt ggtccagtag
     9721 gtccagctgg taaggacggc caagatggtc tcccaggtaa agacggtaag gatggccaag
     9781 atggcaaaga tggtcttcca ggtaaagacg gcaaggacgg ccaagatggt ctcccaggta
     9841 aagacggtaa ggacggccaa gatggtaaag atggtcttcc aggtaaaccg gctcctaaaa
     9901 caccagaggc ccctcaaaaa ccagataccg caccagatac tccaaaaacc cctcagatcc
     9961 ctggccaatc aaaagacgtg acacctgctc ctcaaaaccc ttctaataga ggtctaaaca
    10021 aaccacaaac acaaggtggt aatcagctcg caaaaacacc agcagctcac gacacacaca
    10081 gacaattgcc agcaacaggc gaaacaacca atccattctt tacagcagct gctgtagcta
    10141 tcatgacgac agctggagtt gtagctgttg caaaacgtca agaaaacaac taatcctctt
    10201 tttgctacct aactgatgga aagtaaaact cagagagaac ctcaaggttc tctctttttt
    10261 gaatcaagat agtagctcta ggtataacgt cttgtctgag gtgctgtgaa caaatcagtt
    10321 accgctcacc tctttttttg gtaaaatgta agcactaaaa catcaaaagg agttttccat
    10381 ggaaacatca gatgagttaa aacaacgcat tggtgatctt tcttacgagg tcacccagca
    10441 tgcagcaaca gaatctccct ttacaggaga atatgataat ttttttgaga agggtatcta
    10501 tgtcgatatt gttagtggtg aagtcttgtt ttcatcactg gataaattta attctggctg
    10561 tggttggcct gccttttcaa aacctattga aaatcgtatg gtcacaaacc acgatgactc
    10621 ttcttatggg atgagacgag ttgaggttaa aagccgtgaa gcaggatcgc atttggggca
    10681 tgtctttagt gacggcccca aagaagctgg aggcttgcgt tactgtatca attcagcagc
    10741 tcttaaattc attccttatg accagatgga aaaagaaggc tatgcccaat ggctcacatt
    10801 gtttgatgag acataacagg gtttcaaaat gactaaaaaa gaagcgtcag tgattcccac
    10861 aagcactgga ttggtgaggc gtacgggtca attttacaag cctttgtaaa aggtctataa
    10921 tagggaatga aaaaaggagg ttagtatgtc aactcactta agaaaacttc caggcctgtt
    10981 actttgctta ttgttagctc ttccagcctg gtgtttaggg cgcttgtttc ccattattgg
    11041 agcacctgtt tttgctattc ttttaggaat gttgttagcc ttgttttatg aacatcgtga
    11101 caagactaaa gagggaatta gttttacatc caagtatatt ttgcaaacag cagtggtttt
    11161 gcttggtttt ggattaaacc taacccaagt tatggcagta ggcatgcagt ctttcccgat
    11221 tatcatttca actattgcga cagctctttt ggtagcttat ggcttacaga aatggctgcg
    11281 cttagatgtc aatacagcca ccttggtggg tgtagggtct tccatttgtg gggggtctgc
    11341 tattgcagcg acagctcctg tcattaaggc aaaggatgac gaggttgcta aggcaatttc
    11401 agtcattttt ctctttaata tgttagcagc tttgctattt ccaagtttag gacaattact
    11461 aggcttatct aatgaaggtt ttgctatttt tgctgggaca gctgttaacg acacctcttc
    11521 cgtgactgca acggccacgg cctgggatgc ccttcaccat tccaatacac tagatggggc
    11581 aaccattgtc aaattgactc gcaccttggc tattctccca attactttag gtttatccct
    11641 ttaccgagcg aaaaaagagc acgacatcgt tacagaagaa aacttcagcc ttaggaagtc
    11701 attccctcgt ttcatcctct tctttttatt agcttccctc atcacgacat tgatgaccag
    11761 ctttggtgtt tctgccgata gtttccatta cctaaaaacc ttatcaaaat tctttatcgt
    11821 gatggctatg gcagcgattg gtttaaacac aaacttggtt aaactgatta agacgggcgg
    11881 tcaggctatc cttttaggag ctatttgctg ggtagctatc acccttgtca gtttagccat
    11941 gcaattaagt ttgggcattt ggtaatcaga cacgagaaat cagtttgact gatttctttt
    12001 tttgtatctt atttgtgtag aattgtctac attttaaaga gaatagtgca ttttaaaaac
    12061 gttttcattt gataaaataa acctatcgtt acaccagttc agtaaagaca actggttgag
    12121 ataagcaatt accgtttact cagcggtttt tgttaataga ggaggatagg aatgaaacga
    12181 aaatttctca ttgggagtca cggcagacta gccagtggtt tgcaaagctc tattgacatt
    12241 ttagcaggta tgggacaggc acttgaaacc attgatgctt atgttgatga tagtgactac
    12301 actagccaga ttgatgactt tatcgctggg gtagcagcag atgagcaggg ccttattttt
    12361 actgatttgt taggcggcag tgtgaatcag aaaatggtaa ccgctgtaat gaacagtggc
    12421 aaagacaata tctttttaat cacaaacagt aacttagcca ctttattgtc gttggtgttt
    12481 ttaaaaccag gcgaagcgct tactaaagat gaaattgtaa ccgttatcaa tgaatcgcaa
    12541 gttcagttag tggatttggt ccctgagaca aattcagaag atgacttttt tgattaatat
    12601 ctaggaggaa gacaaatgat tactcaaatt cgtgttgacg accgtttgat tcacgggcaa
    12661 gtggcagttg tatggaccaa agagttaaat gcgccacttt tagtagtggc taatgatgaa
    12721 gctgcaaaaa atgaaatcac acaaatgacg cttaaaatgg ctgtgccaaa cggcatgaaa
    12781 ctgcttattc gttcagttga agactcgatt aagctcttta atgatccacg cgcaactgac
    12841 aagcggattt ttgtgattgt caattctgtt aaagatgctt gtgccattgc taaagaagtt
    12901 ccagacttag aagctgttaa tgtggctaat gtggggcgtt ttgacaaatc agacccagca
    12961 agcaaagtca aagtgacacc aagtctttta cttaacccag aagaaatggc agccgcaaag
    13021 gaattagtca gtttaccaga acttgatgtc tttaaccaag tcttaccatc aaataccaag
    13081 gtccatttga gccaattagt caactaaaga gaggtaaaaa agtatgttag taccagcaac
    13141 aatggcagct ttagctgtat tgatttgttt tgggggaaat tatttaaccg gtcaaagcat
    13201 gatggaaaga cccctagtag ttggactggt cacaggtctt cttttaggag atatgaaggt
    13261 cggtatctta atgggggcct ctctagaagc tcttttccta ggaaatgtga atattggggg
    13321 tgttattgca gctgagcctg taacagcgac tgccatggca acaaccttta ccattatttc
    13381 acatattgac caaaaagcag ccatgaccct agctgttcca attggaatgt tggcagcctt
    13441 tgtggttatg tttttgaaaa acgtcttcat gaatatcttt gctccaatgg ttgataaagc
    13501 tgcagcagct aaccatcaag gtaaactagt gatgctccac tatggcactt ggattatcta
    13561 ttacttaatc attgcctcta tttctttcat tggtatttta gtaggtagtg gacctgttaa
    13621 tgcctttgtg gaacacattc ctcaaaatct catgaatggc ttgagtgctg cgggaggcct
    13681 tcttccagct gtcggttttg ccatgctgat gaaattattg tggaccaaca aattagctgt
    13741 tttttaccta ttgggctttg tcttaacagc ttatttgaaa ttaccagcgg ttgcagttgc
    13801 tgccctagga gcagttattt gcgtcattag ttcccaacgt gatctagaat tagacgcaat
    13861 tactagaggt gcaattaata aacaaacaac ctttgactct aaagaatcag aagaggagga
    13921 cttcttcgca tgacatcaca agataatttg actaaagaag accgtaaaat gcttcgctca
    13981 gtcttttggc gctcatggac gatgaatgct agtcgtactg gggcaacaca ataccacgca
    14041 gtaggggtta tttacacttt actaccagtc atcaatcgtt tttataagac tgataaggat
    14101 aaagcagagg cactggtccg tcatacaaca tggttcaatg ccaccatgca catcaataac
    14161 tttatcatgg gtcttgtggc atcgatggaa aagaaaaaca gtgaagatcc tgattttgat
    14221 gctagtgcta tcaccgctgt taaggcttcg ttgatgggac ctatatctgg agttggagat
    14281 tccttcttct ggggaatttt aagggttatt gcggcaggta tcgggatttc cttggcaagt
    14341 gcaggctcag ccatgggagc tgttgtcttc ttactcttgt acaatattcc tgcttttatt
    14401 attcactact atagccttta tggtggttat tctgtaggtg caggatttat caaaaaactt
    14461 tacgaatctg gtggtataaa aatcgtcact aaaacctcaa gcatgcttgg gttaatgatg
    14521 gtaggctcaa tgactgcttc aaatgtaaaa tttaaaacga ttcttacagt tgctgcgaaa
    14581 ggtgccaaag aagcagcttc tattcaagat taccttgacc aattgtttat tggtattgta
    14641 ccattactgg taacactagc agctttttgg cttctacgaa agaaagtgaa tatcaactgg
    14701 attatgtttg gtatcatgtt ccttggcatt atccttggac ttttaggtat ttgctaataa
    14761 tctcctagca ataaaggtaa gtaagacaag gtttcttgtt ttgcttacct ttttcctttt
    14821 aagatgatga gacttgtttt gatgaaaaac gtagtagcat taagaaattt gttataatga
    14881 aaggagctta agatgcgagg tgaacaggtg gaagaacatt ttaaaaaaca attacaagat
    14941 gatatttcta gacatttttc gtaccaatcg ttaatgttat cattgttgct aattggtctt
    15001 tttattattt tttcattagc gccacaacaa ttaggcctct atcgtgatat caatgccact
    15061 gcaacccgtt atcaccgttt gattagcaaa caagaagcct tgctggatga attagggaaa
    15121 aatagcttac tacctttttt aaataaaaac ctcagcactg ctgatttaag caagcactat
    15181 tttcatttgc gccatagcag ccaaacgtca ccagaacttt tactattttc acctaatcaa
    15241 ggccttttat ttgctagtaa cccacattta ggaaatactt ttagtaaatc tgtttatatt
    15301 caagaagtct tgagagcagc tcatcctcca aaaaccttgt ttaaagttgc tatggatagt
    15361 gaagatggtc actacttgat gatcattaag ccaatgattg atcaaaacca actaaaggga
    15421 tatgcttttt tagtgatgag tggcaaagat tttcttcatc ctacaaaaac attgacgtca
    15481 gagttggtca ttgctgataa gctggacaac acgtttacgt tttccaatcg tgagtttata
    15541 gcatctagtc tagataagat caatagcaag tatttacacc attattttgt ttttcaagat
    15601 aatcgagcct ttatcacaag aaaggtttcc ttacaaggag gtctttggct ttacatgtat
    15661 aggcccttga ttccaatggt atcggtgatg ttattttcac ttatttcatc agctgttatc
    15721 tttgtgatct tgcaacgtaa atcaagtggt ttagctaacc gaattgcagc taaaaattca
    15781 agagcaatca atcaaatggt tagagatatg agtgcgatct ctcggcaaga aaaaagacgt
    15841 attgaccttg agagtcaaga tgaatttcaa tatttatctg atcaaatcaa tcaaatggta
    15901 gagcgattgc aacagttaca tgataaaacg ttagatttgg aaactcaaaa attattattt
    15961 gaaaaacgga tgttagaagc tcaattcaat ccgcatttcc tctacaatac gctagaaacc
    16021 attttgatta cgagccatta tgattctgcc ctaacagaaa aaattgttat ccaattgaca
    16081 aaattgttgc ggtatagtct cacggattct agcaaacctg tcttgctcaa agatgattta
    16141 agtgtcatcg agtcttattt agtgattaat caggtgcggt ttgaagaatt gcaatatagc
    16201 attaacctat ccccagacct tgatagtctt gcagtgccta aattgttctt gttacctttg
    16261 atagaaaatg ccatcaaata tggcttgaaa gaacgacacg atgtcaagat taacattgct
    16321 tgttattatc aagatgacca cattattttt tctgtgcgag ataatggttc gggaattgat
    16381 gctcatcacc aaaaagtgat tcgagagcaa ttggaagctg gagagtcaca ccatgggtta
    16441 attaactctt atcgtcggct taagtatcat ttttcagaag tatccttggt ttttgatcaa
    16501 ggtgataaac agtttaatgt tagttaccat gttaaggagt agtctatgta caaattagtc
    16561 attattgaag atgaacatat tattaggaaa tggttgcgat acgctattga ttataaagct
    16621 ttagatactt tggtcattgg cgaggctaaa gatggcaaag aaggagctgt tttaatcaaa
    16681 gagagtcaac cagatatcgt tttaaccgat attaacatgc ccatcatgac agcttttgac
    16741 atgtttgaag caacaaaaga tcaaacttac gccaaaatta ttttatctgg ctatgctgat
    16801 tttccaaatg caaggtctgc catacactac ggtgtacttg aatttttaac aaaaccgatt
    16861 gaaaaagcag ctctttggga atgtcttcaa accattattg ctaaaataga aaagcaaaag
    16921 gggtctaatc aaaaaacaga tgcttgcgtc tatattccct taccccagat gactgatcag
    16981 attcctgaag tagtcaaaga tattttggag tgggtacatg ctcattttca agacaagatc
    17041 agcacgagcc gcctagctca tgacttaggg tatagtgaga gttatatcta tcaaaatatc
    17101 aaaaagcatc ttcagatgcc tttaagtgat tacattaatc aatatcggat taatcaggca
    17161 attcaattga tgcaacaaga accagattta atggtatatg aaatagcaca agctgtaggt
    17221 atttatgact atcgctattt tgatagggtt tttaaaaagt atctaggaca aactgtaaag
    17281 gcttttaaag aagagcattt tatgaaagat accgatagga gtatgtcatg acaaagctta
    17341 aagggaagtg gtttatcggt ctattgtgtc ttgttatact ggctctgagt ggcggagcgt
    17401 tggctctaaa gacgttgtct tcaaagcaac agatgcctaa ggaactagtg attttgagcc
    17461 caaacagcca gacaatttta acaagcacca ttccagcttt tgaagaaaaa tatggcatta
    17521 aggttaggct gattcaagga gggacaggtc aattaattga ccaattgcgt caaaaaaata
    17581 agcagttaaa ggcagatatt ttctttggtg ggaactacac gcagtttgaa agtcataaag
    17641 atttgtttaa atcctatgtt tcccctcaag tggctaccgt tatttcggac taccaattac
    17701 ccagccaccg tgccacacct tacaccatta atggcagtgt actgattgtt aataatgaat
    17761 tagcacaggg ccttaccatt actagttatg aggacttgct tcagccggcc ttaaaaggga
    17821 agattgcttt tgctgatccc aacagttcat caagtgcctt ctcacagctg actaatatat
    17881 tgttagctaa gggggggtac acaaacgctg acgcttgggc ttacatgaag cgcttgttgg
    17941 tcaatatgaa ttctattagg gctacgagtt cttcagaagt ctatcaatct gtcgctgagg
    18001 gtaagatgat tgttgggcta acctacgaag atccttgtat caacctgcaa aaaagtggtg
    18061 ccaatgtttc cattgtttat ccaaaagaag gaacggtgtt tgtgccctcc tctgttgcta
    18121 ttatcaaaca tgcgccaaac atgacagagg ctaagctctt tattaatttt atgttatcac
    18181 gtgatgtgca aaatgccttt ggccaatcaa ccagtaaccg acccattcgt caagatgccc
    18241 aaaccagtca cgacatgaaa gccttagaaa cgatagctac tttgaaagag gattatgctt
    18301 atgttaccaa gcacaagaaa aaaatagtgg ctacgtacaa cctgttgcgc caacggttgg
    18361 aaaaagctaa gtaggagtta aaagtatggt attgtcaact tgaaaaaggt cctaaggcct
    18421 tttttctatg ttataattaa gaatcatctt cagttgagaa agtaaggatt atgccaccaa
    18481 aaaccattga tattgaaaag taccaccagc ttgcttggca aaggcaggct gaacaccgaa
    18541 agtttttagc gactttaaag aaaaaaccac ctaaacatct agacaaaatt gtccaggaca
    18601 ttcatcagga ggtttttcaa gagattgatt gcacgtccag tgctaattgt tgcaaagacc
    18661 ttggacctga tttgacagag accgatattg tcaaaatcgc taaactattc cgaatgaaat
    18721 tagcgacttt tgaaaagact tacttgcgcg tggatgagga tgatgataag gttttccggt
    18781 tcatgccctg tcctttttta ggaggggata acctttgaag cacttatgat gtaaggccta
    18841 aagcttgccg agaattccct cacacagacc gtaaaaaaat ctaccagatt aatcacctca
    18901 cttcaagaac accttgattt gtccagccac ctacgagttt gtggagcggt taagcaaacg
    18961 tttgacccgt tcttaggcta gaaaaaggtg ttcttgtagt agaaagtgta tttattatca
    19021 cttttgacaa aaaatctctt tccctaattg ttctaaagag gcgacaatcc ttaatcactg
    19081 ttaacaaaca gttaaccgat aagtggatta aggtttgtca tctcaaataa aataccctca
    19141 aaaggagacc ttatgaccac agaatttgac aaaatgacta gaggcgaatg gtatgatgct
    19201 aattttgatt cggaactgat tcaaaaacgc atgatggcac aagacctctg tttcgattta
    19261 aaccaattaa agcctagtcg agaagaagaa cgctctgccg ttttaaacca actttttgga
    19321 caatcttttg agggcttggt cctgctcagc cctttcatct gtgactatgg taagaacatt
    19381 acttttggga agaattgctt tattaacagc aattgttatt tcatggatgg ggcgaagatt
    19441 gccttgggcg ataatgtctt tgtaggtcct tcgacaggtt tttacacggc aaatcaccct
    19501 ctagattata aacgccgcaa tgaggggctt gaaaaagctt taccaattac cataggagat
    19561 aatgtctggt ttggtgccag tgtcaatgtt atgcccggcg ttactattgg cagtggttgt
    19621 gtgattgcgt caggatcagt tgttacccat gatattccag tcaattccct tgcggcaggt
    19681 gttccttgcc aagttgtacg ggaaattgag caggagtaga aagtgaggca aaaagtgcat
    19741 tacaactttc tttttttcga ccttgaccat accctacttg attttgatgc ggcagaagag
    19801 gttgctttga ccaagttgct agaagagtac caggttattg atattaaggc ttacaaggac
    19861 tactataagc cgatgaatca gaacttatgg aaacagttag aaggtgggga tactagtaaa
    19921 gctgatttgg ttaactctcg ctttgctctg ctatttgctc attttggagt gacggttgat
    19981 ggcaggcagt tagcagaagg ttatcaaaag catttaaaag atcaagggca agtttatgct
    20041 ggtgctaagg agctgttagc ggacttaact gcccaaggct ataatcttta tgcggcaact
    20101 aatggtatcg caacgattca acaaggccga ttgcaagcgt ctggtttggc accttacttc
    20161 aaagccattt tcatttcgga acagtcgggt agtcaaaaac ctaaaaaagc tttctatgat
    20221 tggatgaccc agcaggtttc ccattatcaa cctgatcaag ctttgatgat tggtgatagt
    20281 ttatcggctg atgttcaagg tggaattaat gctggcatgg ataccttatg gtacaaccca
    20341 aagcatctcc tgaataacag ccctgttcat cctacctatg aggtgtcaga ttatcaagct
    20401 ctgctgaatt gtattgcgga gtaacagaca atagccttta aaaatagcgt agtcattttt
    20461 tgaaatcgat ttcataatct ggtagactaa ggttatcacg aaaaggaggc tatatgtgat
    20521 ggcttatcaa actatttacc cttatacaaa tgaagtcctt catacatttg ataatatgac
    20581 cgaccaaggt gtggcagatg tccttgaaag agctcacctt ctctataaaa aatggcgcaa
    20641 ggaagatcat ttagaagaac gtaaagccca gcttcatcaa gtggctaata ttcttcgccg
    20701 tgaccgcgat aaatacgctg aaatcatgac caaagacatg ggaaaactgt tcacagaagc
    20761 ccaaggtgaa gtagaccttt gtgccgatat tgctgattac tacgctgata aggcagatga
    20821 attcttgatg tctatgccac tagaaacgga ttcaggtcaa gcttactatt tgaaacaatc
    20881 aactggtgtt atcctagctg ttgagccttg gaattttcct tactatcaaa tcatgcgggt
    20941 ttttgcgcca aactttattg ttggaaaccc aatggtttta aaacacgctt ctatttgccc
    21001 acgctctgcc caatctttcg aagaattagt tcttgaagct ggtgctgaag caggtagtat
    21061 taccaatttg tttatttctt atgaccaagt atcacaagtg attgctgata aacgtgtggt
    21121 tggtgtctgc ttgacaggtt ccgaacgtgg aggagctagc attgcagaag aagctggtaa
    21181 aaacttgaaa aaaacaaccc ttgaattggg tggcgatgat gcctttatta tccttgatga
    21241 cgcggattgg gatcaattag agaaggtgct ttacttctct cgtctctaca atgcaggtca
    21301 agtatgtacc tcatcgaaac gttttatcgt gcttgacaaa gactatgacc gtttcaaaga
    21361 gttattaaca aaagtcttca aaacagctaa atggggtgac ccaatggatc ccgaaacgac
    21421 gttggcgcca ttatcatcag ctcaagctaa agcagatgtt cttgaccaaa ttaagttggc
    21481 cttggatcat ggtgcggagt tggtttatgg tggtgaagcg attgatcatc caggtcattt
    21541 tgtcatgcca accattattg ctggcctcac aaaagacaac cctatttact atcaagaaat
    21601 ctttggccca gtcggtgaaa tctacaaagt gtcttctgaa gaagaagcga ttgaagtggc
    21661 gaatgattct aactatggcc ttggaggtac tatctttagt agcaatcaag aacatgcgaa
    21721 agccgtagct gctaaaattg aaactggtat gtcttttatc aactcaggct ggacaagtct
    21781 tccggaactc ccatttggtg ggattaaaca ttcaggctat ggccgtgaat tgagtgagct
    21841 tggctttaca tcttttgtga atgaacacct tatctatatt ccgaataaaa cgaataatag
    21901 caatactaaa gtttgatcta gattgttaaa ggagatctgc tcgccttaat aaacaatcaa
    21961 ggcgttacac tcttcttttt taaagtcaaa attttaaaaa tttgataaac tagtaacatg
    22021 aacgaactga ttaaacataa actagaactc ttaccagaca gccctggctg ttacttacat
    22081 aaagataaag aaggaactat tatctatgtc ggtaaggcca agaatttgaa aaaacgcgtc
    22141 cggtcctatt ttcgtgggag ccatgatacc aaaacagaat tattggtgtc tgagattgct
    22201 gattttgaat ttattgtgac cgaatcaaat actgaggctc tcttgcttga aatcaacttg
    22261 attcaagaaa acatgcccaa gtataatatc aagctcaaag atgacaagtc ttatcctttt
    22321 atcaaaatca ccaatgagtc ttttcctcgg ttagtgatta caagatatat taagaaaaat
    22381 gatggattgt actttgggcc ctacccagac tcttacactg ctaatgaagt taaaaagtta
    22441 ttagatagga tttttccatt taaaaagtgt aaaaatccta tcaataaggt ctgtttttat
    22501 taccatttag gccagtgctg tgctcatacc atttgtcata cagacaaggc ctattgggat
    22561 cgtttaattg atgatgttaa gcacttttta aatggtaaag atgacaaaat tattgaagat
    22621 cttcgttcta agatgttagc agcttctgaa gaaatggcat ttgaacgtgc cgctgaatat
    22681 cgagatttga tttcaggtat tgccaccatg cgcaccaagc agcgggtgat gagcaaggat
    22741 ttgcaagata gagatatctt tggctattat gttgataggg gatggatgtg tgtccaagtt
    22801 ttctttgtgc gtcaagggaa attaattcag cgtgatgtta acctttttcc ctattataac
    22861 gatgcagaag aagatttctt aacttatatg gggcaatttt accaagataa acagcatttc
    22921 atccctaaag aagtctttat tccagaagct attgatgaag aactggtagc cgctattgtg
    22981 ccaaccaaaa tcatcaaacc caaacgcggt gaaaaaaaac aactggtagc tttggctact
    23041 aagaatgctc gtgttagtct gcaacaaaaa tttgatttat tagaaaaaga tatcaaaaaa
    23101 acgagtggtg ctatcgaaaa tttaggtcag ttacttagga ttgacaagcc tgtgcgcatt
    23161 gaagcctttg ataattctaa cattcaaggg acaagtccag ttgcggctat ggttgttttt
    23221 gttgatggca aacctagtaa gaaagattat cgtaaattta agattaaaac agtggtggga
    23281 ccagatgatt atgccagtat gagagaagtg ctttttcgaa ggtacagtcg ggtgaaaaag
    23341 gagggactgc aagctcctaa cttgattatt gttgatggag gcgttggaca agtcaatgtg
    23401 gccaaagatg tgatagaaaa acaacttgga ctcactattc ctgttgcggg acttcaaaaa
    23461 aacgataagc accagaccca tgatttgctt tttggaaacc cacttgaagt tgtaccgttg
    23521 ccgcgccgtt ctgaagagtt tttcttactg catcggattc aagacgaagt gcatcgcttt
    23581 gcagttacat ttcatagaca agtgcgacgt aaaaattctt tttcatcaac attagatcat
    23641 atttcagggc ttggcccaaa gcgaaaacag ttattactaa gacactttaa aaccataaca
    23701 gcgattgcat cagctacctc tgaggagatt caagctttag gtatacctaa aacagtagtt
    23761 gaagcaatac agcaacagat aacagacaat aaaaatgata gatcgtctcc ttaaataagt
    23821 gttatgtttt cagtactgat gaggtaaaaa ggcgctactt gttacgcacg acatttcagt
    23881 tcgttatttt gaaactttca gaaagttgcg aagtgtagtg agtttatgat tttaaaaact
    23941 attttatggt aaaataaaat ggtataaaaa aaaaaacaga tttagatagg aagttttgaa
    24001 atgaaatttc tagagttaaa caaaaaacgc catgccatta agacctttaa tgaccagcca
    24061 gttgactacg aggatttgcg aacagccatt gagattgcaa ccttagcacc tagtgccaat
    24121 aacattcaac cttggaaatt tgtagtcgtt caagagaaaa aagctgagtt agcaaaaggg
    24181 ttacctctag caaataaagt gcaggttgaa caggctcaat atgtagtggc gctattttca
    24241 gacactgatt tagctttacg ttctcgtaaa attgcccgta tcggtgtcaa atcattacca
    24301 gacgacttaa ttggttatta tatggagact ttgccaccac gttttgctgc ttttaatgag
    24361 gttcaaaccg gtgagtactt agctattaat gcaggcattg tggctatgaa cttggtgtta
    24421 tccttgacgg atcaaaagat tgcttccaat attatccttg gttttgataa gtcaacgacc
    24481 aatgagattt tagacatcga tccgcgtttt cgtccagaat tattgattac tgttggctat
    24541 agtgacgaga aaccagaacc aagttatcgt ttgcctgttg atgaagtcat cgaaagaaga
    24601 tagagtcagg acaattagtt aaatgtaatg tccagatgcg ctactgagcg accactattg
    24661 ttagactgat actattttgg cttattttaa gttaaacatt atccctaaaa cgaataagga
    24721 gagtataatg acaaccattg attttaaagc agaagttgac aaacgtaaag aagctatgtt
    24781 agcagattta gttgacctat tacgcattaa ttcagaacgc gatgaccaat tagctgatga
    24841 taaacaccca tttggcccag gtccagttaa ggctttggag catttcctcg caatggctga
    24901 gcgtgatggc tacaaaacgc gtaatattga taactatgca ggtgactttg aatttggtca
    24961 aggtgatgaa gtactaggaa tctttgggca ccttgatgtt gtgccagctg gtagcggttg
    25021 ggatacagac ccttatgagc cagtgattaa agacgatcgc atctatgcgc gtgggtcttc
    25081 ggatgataag ggaccaacca tggcgtgcta ctacgctctg aaaatcatta aagaattggg
    25141 tcttcctgtg tctaaaaaag ttcgtttcat tgttggtacc gatgaagaat ctggctgggg
    25201 ggatatggat tattactttg cccataacgg tttgaaaaat ccagactttg gtttctcacc
    25261 agatgctgaa tttccaatta tcaatggtga aaaaggaaat atcaccgaat acctccattt
    25321 cgctggtgac aacaagggtg cttttgtgct tcatcgcttc caaggtgggt tgcgtgaaaa
    25381 catggtacca gaatctgcaa cagctgtcat cacgtcaccg catgacctta atgtgctaga
    25441 agcagccttg gagcaatttt tatcagaata tggtgttaaa ggctctatga aggctactga
    25501 tggtaaaatt gaagtaacta ttattgggaa gtctgctcac gggtcgactc cagaagctgg
    25561 aatcaatggt gccaccttgc tggctaaatt cctgaatcaa tttacctttg aaggggctgc
    25621 taagtattat ttacatgtgg caggtgaggt gcttcatgaa gactttgcgg cagaaaaact
    25681 aggccttgct tataccgatg accgtatggg agccctgagc atgaacgcag gtgttttcac
    25741 ctttgatagt caatcagctg acaataccat cgccttgaat ttccgttatc caaaagggac
    25801 tgatgcggca accttaaaag caggattgga aaaattacca ggattaacta aggtaagcct
    25861 ttctgagcat gaacatacac ctcattatgt gccaatagat gatgaattag tagctacctt
    25921 acttgctgtt tacgaaaaac aaacaggtct taaaggctac gaacaagtta tcggcggagg
    25981 aacctttggt cgtttgctag aacgtggtgt ggcctttgga gcgatgttcc caggtgatga
    26041 aaacactatg caccaagcta atgaatatat gcctttagaa aatatttatc gctcagcagc
    26101 tatttatgct gaagcaatct acgaattaat taaataagat gcttatgaca gcaaaaagag
    26161 ctggaacact gttccagctc ttttgcgatg attagagaat ggtcttattt accaagacag
    26221 aattggctaa agagttgggt aatgagttca tcaggagcag catcccctgt gatttctccg
    26281 agaatttccc aagttctggt taaatcaacc tgtagtaaat caactggcat gccaagggct
    26341 aaaccatcat tgacagcttc taaactctgg actgcctttt caatcaaaga aatgtggcgg
    26401 gcatttgaca ggtaagtggc atcttgttct actagtccag cattatcaaa gaagagctgg
    26461 ttgatacgat cttcgattag attaatgttc tggttggtta aaacggaaat gggaatgtag
    26521 tcatctggta attgctctaa ttcaatcttt tgttccaaat ccgttttatt caacaatata
    26581 atacggttac tgtcctgact gagatttaac aaagcccagt cttggtcggt cagtttttca
    26641 gaagcattca gcacaagaag aacaaggtca gcttcttgaa gagctttttt agaccgttca
    26701 actccgattt gttcgaccag atcatctgtc tcacgaatac cggccgtatc gacaagtttt
    26761 agaggaactc ccttgatatt aacgtattct tcaatgacat ctcgggtggt tcctgcaata
    26821 tcagtcacaa tagccttgtc ttctcgcaac aaattattaa gtaagcttga cttaccgacg
    26881 tttggacgac caataatagc tgttgataag ccctcacgca gaattttacc gcgtttagct
    26941 gttcgaagga gattttccaa aaggctttgg aattcttgtg ttttctcacg tagcagagca
    27001 gtggtcattt cttccacatc gtcgtattca gggtagtcaa tattgacttc gacttgagct
    27061 aaggtgttga gaatttcctg acgggtgtca ttgataagct gggaaaggga gccatccagt
    27121 tgcttgactg caatcgtcat agccttgtct gttttggcac gaataatgtc catgacagcc
    27181 tcagcttgag tcaaatcaac tcgcccattt aagaaggcac gtttggtgaa ttcgccaggc
    27241 tctgccattc tagcgccttg gcgaatcaat agttgcaaga tttcatttgt cacagcaata
    27301 ccaccgtgcg tattgatttc aaccacattt tcacgggtaa aggttttggg ggctagcatg
    27361 actgacacca taacttcatc gataatagtt cctgtcttag gatcaatgat atggccatag
    27421 ttaatggtgt gtgaggcgac ttgctctaag ttctttccct taaaaacaga ttgtgtaatg
    27481 gcaagcgcat ctgtcccgga tagacgaaca atgccaatag ctccttcacc aagaggggtt
    27541 gaaatggcgg taattgtatc aaattcttta gttatactca tgccctctat tttaaatcaa
    27601 gtcctagtag aaagcaaggt attattttgt atagaaaata ggactagcac
//
LOCUS       DAUGSW010000020        27132 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUGSW010000020 DAUGSW010000000
VERSION     DAUGSW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27132
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.020"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            3..500
                     /locus_tag="VIB18_001029"
     CDS             3..500
                     /locus_tag="VIB18_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEQ8766044.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            520..690
                     /locus_tag="VIB18_001030"
     CDS             520..690
                     /locus_tag="VIB18_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766045.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            820..2049
                     /gene="clpX"
                     /locus_tag="VIB18_001031"
     CDS             820..2049
                     /gene="clpX"
                     /locus_tag="VIB18_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEQ8766046.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            2059..2658
                     /locus_tag="VIB18_001032"
     CDS             2059..2658
                     /locus_tag="VIB18_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEQ8766047.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            2806..3549
                     /locus_tag="VIB18_001033"
     CDS             2806..3549
                     /locus_tag="VIB18_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766048.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(3607..5706)
                     /locus_tag="VIB18_001034"
     CDS             complement(3607..5706)
                     /locus_tag="VIB18_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8766049.1"
                     /translation="MTHFSGKDPFINMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSESNTMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQNDQ"
     gene            6084..6767
                     /gene="rpiA"
                     /locus_tag="VIB18_001035"
     CDS             6084..6767
                     /gene="rpiA"
                     /locus_tag="VIB18_001035"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEQ8766050.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPKAG"
     gene            6844..8055
                     /locus_tag="VIB18_001036"
     CDS             6844..8055
                     /locus_tag="VIB18_001036"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEQ8766051.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLGHLK"
     gene            8074..8514
                     /gene="arsC"
                     /locus_tag="VIB18_001037"
     CDS             8074..8514
                     /gene="arsC"
                     /locus_tag="VIB18_001037"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEQ8766052.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYMKEDGEIVNPIEVKGEKDVIDD"
     gene            8498..9307
                     /locus_tag="VIB18_001038"
     CDS             8498..9307
                     /locus_tag="VIB18_001038"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8766053.1"
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            9892..10605
                     /gene="deoD"
                     /locus_tag="VIB18_001039"
     CDS             9892..10605
                     /gene="deoD"
                     /locus_tag="VIB18_001039"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8766054.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGRRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            10598..11386
                     /locus_tag="VIB18_001040"
     CDS             10598..11386
                     /locus_tag="VIB18_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEQ8766055.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(11466..12371)
                     /locus_tag="VIB18_001041"
     CDS             complement(11466..12371)
                     /locus_tag="VIB18_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8766056.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHSKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            12593..13129
                     /locus_tag="VIB18_001042"
     CDS             12593..13129
                     /locus_tag="VIB18_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766057.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     ETFIKYYQSPKVPTGEFE"
     gene            13406..14098
                     /gene="pyrF"
                     /locus_tag="VIB18_001043"
     CDS             13406..14098
                     /gene="pyrF"
                     /locus_tag="VIB18_001043"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEQ8766058.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVWYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            14156..14785
                     /locus_tag="VIB18_001044"
     CDS             14156..14785
                     /locus_tag="VIB18_001044"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEQ8766059.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLRKFKEDQVNWQQ"
     gene            14982..16436
                     /locus_tag="VIB18_001045"
     CDS             14982..16436
                     /locus_tag="VIB18_001045"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEQ8766060.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPTTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELAP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            16554..17417
                     /locus_tag="VIB18_001046"
     CDS             16554..17417
                     /locus_tag="VIB18_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8766061.1"
                     /translation="MKKSVTLLSIGLASLLLAACVPHQSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            17446..18096
                     /locus_tag="VIB18_001047"
     CDS             17446..18096
                     /locus_tag="VIB18_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8766062.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            18229..18882
                     /locus_tag="VIB18_001048"
     CDS             18229..18882
                     /locus_tag="VIB18_001048"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEQ8766063.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESSHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            19014..20282
                     /locus_tag="VIB18_001049"
     CDS             19014..20282
                     /locus_tag="VIB18_001049"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEQ8766064.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(20340..20981)
                     /gene="plsY"
                     /locus_tag="VIB18_001050"
     CDS             complement(20340..20981)
                     /gene="plsY"
                     /locus_tag="VIB18_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEQ8766065.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            21116..23065
                     /gene="parE"
                     /locus_tag="VIB18_001051"
     CDS             21116..23065
                     /gene="parE"
                     /locus_tag="VIB18_001051"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEQ8766066.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMAEILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKVSYAWTDGEL
                     EDLRKEFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            23156..25615
                     /gene="parC"
                     /locus_tag="VIB18_001052"
     CDS             23156..25615
                     /gene="parC"
                     /locus_tag="VIB18_001052"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEQ8766067.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVRSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            25693..26760
                     /locus_tag="VIB18_001053"
     CDS             25693..26760
                     /locus_tag="VIB18_001053"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEQ8766068.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            26824..27054
                     /locus_tag="VIB18_001054"
     CDS             26824..27054
                     /locus_tag="VIB18_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEQ8766069.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
BASE COUNT         8473 a         4853 c         5682 g         8124 t
ORIGIN      
        1 taatgacaaa ggaaattatt gctatttggg cagaggatga agcagggctt attggtgttg
       61 cgggtaagtt accatggtat ttaccaaaag agttagaaca ttttaaaaag acaacgctac
      121 atcaagcaat cttaatgggc cgtgtgactt ttgaaggaat gaattgcaaa agacttcctc
      181 aacgtcaaac ccttgtcatg acaagaaata gagattatca agtagatgag gtgttgacaa
      241 tgactagtat tgaaaaagtc ttggagtggt accatgcgca ggataaaaca ctttatatca
      301 ttggtgggaa taaggtttta gaagcgttta atggttattt tgatcgtatc ataaaaacag
      361 ttatccatca tcgttttaaa ggagatacct accgacccaa tctagatttt agtcatttca
      421 cgcaagaaag ccaaacgttc tatgctcgag acgctaaaaa tccttatgat tttaccgtta
      481 ctgctttaaa acacaaatag tctgaggaga tgataagcga tgcaacgtag tatttttgga
      541 gtatttacgg cttttttgtg cgtgatttgt gttctttgtg ccatcccagc ttttaaaaag
      601 aatcgttatg gcttaggaag tctgttctta ttaaatgcgt ttactaatct ggttaatagt
      661 attcacgcct tctatggtac attgttttga gatacgactt gcaaagacag cactggtgaa
      721 gatttagcta tcaagcaaga atcaccaaaa accaatacaa cacattgact aatattaaaa
      781 ttcagtaaaa gataagagaa agtaagagaa ttataagaaa tggcaggaag tagaactaac
      841 gatattaaag tatactgttc attttgtggt aaaagccagg atgacgttaa aaaaattatc
      901 gcaggaaata atgttttcat ctgcaatgaa tgcgtagctt tatcacaaga aattataaaa
      961 gaagaattgg ctgaagaagt ccttgccgat ttgacagaag ttccaaaacc aaaagagctc
     1021 cttgatgttt taaatcaata tgtggttggt caagatcgtg ctaaacgtgc tttatcagtt
     1081 gctgtgtaca atcattataa gcgtgtctcg tttacagaaa gtcgtgatga cgatgatgtg
     1141 gatttacaaa agtccaacat tttgatgatt ggaccaacag gttcaggaaa aaccttctta
     1201 gcacaaactc tggctaaaag cctcaatgta ccatttgcta ttgcagatgc aacttctttg
     1261 actgaagcag ggtatgttgg agaagatgtg gaaaatattt tactcaaact gattcaggct
     1321 gctgactata atgtcgaacg agcagagcgt ggtattattt atgttgatga aatagataag
     1381 attgctaaaa aaggtgagaa cgtatctatc acacgtgatg tatctggtga aggtgtacag
     1441 caagcccttc ttaaaattat tgaaggtacg gtagcaagtg ttcccccaca aggtgggcgg
     1501 aagcacccta atcaagaaat gattcaaatt gataccaaga atatcttgtt tattgttggg
     1561 ggagcctttg atggcattga agacattgtc aaacaacgtt taggagaaaa agtcattggt
     1621 tttggtcaaa acagccgaaa aatcgatgac aatgcttctt atatgcaaga gattatttca
     1681 gaagatatcc aaaaatttgg tcttatccca gagtttattg gacgcttgcc agtcgtagct
     1741 gctcttgaac aattaaacac atcagatttg attcaaattt tgacggaacc aagaaatgcc
     1801 ctagtcaagc aatatcaggc tcttctttct tacgatggtg tcgaattggc atttgataag
     1861 gaagccttag aagccattgc aaataaagcc attgagcgta agacaggcgc gcgtggtctt
     1921 cgttctatta tcgaagaaac gatgttagac attatgtttg aaattccaag ccaagaagat
     1981 gtcacaaaag tgcgtatcac caaggctgct gtcgaaggca agtcaaaacc cgttttagag
     2041 acagcttaag gagaaataat ggctgaagaa caagtcttaa atacccataa cgcctcaatt
     2101 ttgttgagcg ctgcgaacaa atctcactac cctcaagatg acctgccaga aattgccctt
     2161 gctggacgtt caaatgttgg taaatcaagt tttattaata ccatattggg gcgcaaaaat
     2221 ttggcaagaa cctcaagcaa gccaggaaaa acccaactat taaatttttt caatattgat
     2281 aacaagctta gatttgtgga tgtccctggt tatggctatg ccaaggtttc taaaagtgaa
     2341 cgggccaaat ggggaaagat gatcgaagaa tacttaacca gcagagacaa tctgcgtgca
     2401 gtcgtgagtt tggttgattt acgtcatgcc ccttcaaaag aagatattca gatgtatgac
     2461 tttttgaagt actatgacat tcctgttatt gttgtggcaa ccaaagcaga taagattcct
     2521 cgtggcaaat ggaacaaaca tgagtctgtg gtcaagaaag ctttgaattt tgacaaatct
     2581 gatactttta tagtattttc ttcggtagaa cgtattggta tcgatgattc ttgggatgct
     2641 attttagagc aggtctagcg ataggtgttg atttatctat gctaaaacat tctcagtaga
     2701 gggtgttttt cttatcgaaa acataaaaaa tcatagttag gtttaccgat tttacttgac
     2761 gccttaatga tgacatgcta gtattttata ttaaggagat gagtcatgac acaagtagcc
     2821 caagggcgct ctaaaggaaa gtcattgtta tgccatcaat gcaatgccct ttttgtattt
     2881 attatttttc ttatcttgct tgctgtactt tttggtgttc gatatcgtaa tagctctatt
     2941 gaaggtatct ggcgaacaac aagcattgat cagaagttag gcgatgattt tgctaaacgt
     3001 cttactggtt tgcatcagag ccctcttatt gatgatagtt tattaacgtc atctcagatg
     3061 atactaacag ttaaaaataa caacgttgac ttgagtttta gtgttcaagt tgaacgagac
     3121 atttttgtca aacgtttagc tgcttatcac caaaatgaat tattaaagac attaaaggaa
     3181 aatcatttag ttgttggtga cttgagtagt aaagaacgcc aaattattga gaatagtatg
     3241 ccagctagcc atgaattaga aatgatttta gatcaagctt ttgagaaatt agcttctcag
     3301 atcggaggca aatataatca aaaaacagga catttatctg ctgttgttct caaaggaaaa
     3361 gttaatcgta ttttgcacac cattgatatc aaagaagaag tagcagcggg acatacttct
     3421 ttttcaaaag gattgctcac acctaatggt tattttgatt acaccagatt tggaaagaaa
     3481 cttgagttat taggcgatga aaaaattatt tttaaaaaag cgctaaaaaa aagtccgtca
     3541 agtgtataac gtagtcacaa gacggatttt ttcatgtttt gaaaattatt caattgaaga
     3601 agtttattac tgatcgtttt gcctaatcac tagttgtcct tcttttagga ttgcctgaag
     3661 ttttttgact tctggatggt caagataata atcagttata cggtcacgaa tttcctgttc
     3721 gataatacgt cgtaatggac gagctcccat agcgtgattg taccctaaat ctatcaaatg
     3781 agctttagcg tcatcagcaa tcgttaaact aatacctttt tttgcggtgg tttgatttac
     3841 ttcagctagc attaaatcaa caatttcttc taaattttct ttttgcagat gattaaattt
     3901 aatgatacta ttaaaacggt tcaaaaactc tggtctgaaa taaggtgcaa tgcgatccat
     3961 agtgttagac tcagaagttt ccgtatcttg ttggccaaaa ccggcatttg atgtagcaat
     4021 aataacggta tttttaaagt taatagtatt tccttgtcca tctgtcaatc gtccatcatc
     4081 taacacttgt agaagaagtg taatgatttg aggatcagct ttttcaattt catctagtaa
     4141 gacaatagca taagggttac gacgaacacg ctcagttagg gtattattat tatcatcgta
     4201 gccaacataa ccagccgttg tcccaatcaa ttttgacaca gcagtgcgat cgttatattc
     4261 ggacatatca agtcgaataa tagcatcttt ggaaccaaat aaatcaagtg ctaattgttt
     4321 agctaactct gttttaccaa caccagttgg acccacaaaa aggaaagaac ctattggacg
     4381 gttaccatca tcaaaacctg ctcgatttcg tcgaatagcg cgtgctactg ctgcaacagc
     4441 ctcatcttgt ccgatgacat ggctttttaa gcggctgcta attcctttga gcctttctaa
     4501 atcattagtc cccatgttag agacaggaat accagttaag cgctctacag actctgcgat
     4561 atcattgact gtagcagtga cattttggct ttggttatgt tgctcaattt gcttttgtaa
     4621 tgtttcaatc cgtgtttttg ctgctaaagc tttttcaaag tcttctttgg cgacagcttt
     4681 ttcttgactc tctttttgtt tagctatttc agtttcgagt gtttttaagt cagtgaccgg
     4741 gtgttgcgca gctaaatgag cagctgtcat atccagtaag tcaattgctt tatctggcag
     4801 gctacgctgt gggatgtatt gaatagaata atcaacagca gcttttagaa cattatcagg
     4861 aagggtaata tggtggtgtt gttcataaag attacgaata cccattaaaa tgtgaaaagt
     4921 atcttcagct gatggtgcat tcactttaac ttcattaaag cgacgagcga gagcagcatt
     4981 ttttaaaata gtattgcggt attcgtcttg agtagtagca ccaatcagtg ttaattctcc
     5041 tcgtgacaag gctggtttaa gaatatctgc aagtcccttt gagcctgaat cactgcttgt
     5101 ggcaccagca ccaactattt gatgaatttc atcaaaaaat aagatgatat tcccagcttc
     5161 ttttacttct tgaatcaagt tttgaatggt ctcttcaaag gaaccacgat attgtgtacc
     5221 agcttcaaga ctagaaatat caattgatac gatttccttg tttttaatag cagctgggac
     5281 atctccatta acaatggctt gagctaaacc ttcaatgact gcagttttac cgacaccagc
     5341 atctccgaca aggacaggat tatttttagt tcgtcgtgcc aagatttcag cggtatcttg
     5401 aatttctttg ttacgaccaa tgacggggtc aagatgtcct tgacgagctt cttgtgttaa
     5461 gttagttccg agttgagtca atacactatc agctttaggt gttaacattt gagaatttgt
     5521 tgctttggtt gtcgctacag ggagttgtcc tgtttgacga tagtgttgga attcttcggg
     5581 agttatttcg cgaccgttaa cgagatagcg gggattttcg ctacgataac cacccatgtt
     5641 tgccattaat tggttgaaaa tatcatccat atttataaaa ggatctttac cagaaaaatg
     5701 tgtcatatca gttacctcgc aataaaaaat agactataag atgtttgtaa gcagtcgcag
     5761 aatcgttgtt aggatttcac atgataggaa atcctttgct aataaaatga ttcagacatt
     5821 atttttactc atcttatagt attattataa tcaaaaggtc agtaaaggtc aaacaaaaac
     5881 gcttgatttt caaaaagcta aataaacacg aaaagtaagt gcttatatga tgactttaga
     5941 ataaatcata agttttaaaa agatcatcct attctatagc acttaggctg tcaatgagag
     6001 aaaaacaaat gttttcatta acaagttggc gctttcatgg tataataaag tgctaagacg
     6061 caattctatt ataaggggga atcatggaag cactcaaaaa aattgccggt gttaccgctg
     6121 cgcaatatgt gactgatggc atgaccattg ggcttggaac tgggtcaacg gcttactatt
     6181 ttgttgagga aattggccgt cgcgtaaagc aagaaggact gcaagtggtt ggtgtgacca
     6241 cgtcaagtgt gactagcaag caagcagaag gcttaggcat tcctttaaaa tcgatagatg
     6301 atattgatag cattgacctc accgtagatg gtgctgatga agtggataag gatttcaatg
     6361 gaatcaaggg tggtggcgca gccttactaa tggaaaaaat tgttgcaaca ccaacaaaag
     6421 aatacatctg ggttgttgat gcttctaaaa tggtagagca tctgggtgcc tttaagttac
     6481 cagtcgaagt cgttcaatac ggtgctgatc gtttgttccg tgtctttgaa aaagctggtt
     6541 acaaaccgtc ttttcgtatg aaaggtgata gtcgtttggt gacagacatg caaaactata
     6601 ttattgatct tgatttgggt tgtattaaag atcctgttgc ttttggtcac ctgctagatg
     6661 gaacagttgg tgttgtggaa catggtctct ttaatggtat ggttgataag gtgattgttg
     6721 ctagtaaaga cggcgttact gttttagaag cgcctaaagc aggctagtct tagcatataa
     6781 cagtgttaat atattttata ggtattgggg agtcaaccgt aacctcccct agattggaga
     6841 cttatgtcaa aatttaatcg tattcacttg gttgttttag actctgtcgg tattggtgca
     6901 gcaccagatg ctgacaaatt ctttaatgct ggtgtagctg atacagattc tgacaccctc
     6961 ggtcatattt cagaaacagc aggcttatcg gttccaaata tggcaaaaat tggacttgga
     7021 aacatttctc gtccaatacc actaaaaact gttccaacag aagataatcc tactggttac
     7081 gtgaccaaat tggaagaagt atctcttgga aaagatacca tgacaggcca ttgggaaatt
     7141 atgggcttga acattacgga accttttgac actttctgga atggtttccc agaagagatt
     7201 ttaactaaga ttgaagaatt ctcaggtcgc aaaattattc gtgaagctaa taaaccctat
     7261 tcaggaactg cggttattga tgattttggt ccgcgtcaaa tggaaacagg tgagttgatt
     7321 gtttacacct cagcagaccc agtgcttcaa attgcagccc atgaagacat tattcctgtg
     7381 gaagagcttt acaagatttg tgaatatgct cgctccatca cgcttgaacg ccctgccctt
     7441 ttaggccgta ttattgcgcg tccttatgta ggcgaaccag gaaactttac acgtacggct
     7501 aaccgtcatg actatgcagt gtctcctttc caagataccg ttttgaacaa actggctgac
     7561 gcaggtgtcc caacttatgc cgttggtaag attaatgaca tctttaatgg ttcaggtatt
     7621 acaaacgaca tgggacacaa taagtcgaac agccacggta ttgacacgct tattaagact
     7681 cttcaattac ctgagtttac taagggattc tcctttacta acctcgttga ttttgatgcc
     7741 aactttggtc atcgtcgtga cccagagggt tatcgcgact gcttgcatga atttgacaat
     7801 cgcctacctg aaatcatcgc aaatatgaaa gaagacgatt tgcttctcat cactgctgac
     7861 catggtaatg acccaaccta tgcaggcacc gaccacactc gtgaatacat tccattgctt
     7921 gcctactctg catcctttac tggaaatggt cttattccac aagggcattt tgcagatatt
     7981 tcagcgactg ttgcagaaaa ttttggagtt gatacagcca tgattgggga gtcattcctt
     8041 ggtcacttaa aataaaaaag ttagtaattg ataatggaag aaatcacgat ttatcataat
     8101 ccaaactgtg gcacttcacg taatgttctt gccatgattc gccatgcagg tattgagcct
     8161 actattattg agtatttgca gacgccacct aatcgggaga ctttaattga gctcttacaa
     8221 tcgatgggaa tctctgcgcg agaactcttg cgaaccaatg ttcctgaatt tgaggctcat
     8281 ggattagcaa atcaagcagt agctgagaaa gacgttatta atgccatgtt gacggatcca
     8341 attttgatca atcgtcctat tgttgtgact cgcaaaggag taaaactttg ccgtccttct
     8401 gagaccttac tggatattct tcctgttccc ctgcctagtc cttatatgaa agaggatggc
     8461 gagattgtga accctattga ggtaaaagga gaaaaagatg tcattgatga ctaaaattaa
     8521 cgaaacaaaa gactttttag ttgctaaagg aattgaagct ccagaatttg gattaattct
     8581 gggttcagga cttggtgaac ttgctgaaga agtagagaat cctgttgtta ttgattatgc
     8641 agatattcca aactggggca aatcaacagt tgttggccat gctggaaaat tagtctacgg
     8701 tgatttagct ggtcgtaaag tacttgccct acaaggtcgt ttccattttt acgaaggaaa
     8761 tccgcttgaa gtggtgactt tccctgttcg tgtcatgaaa gctcttggat gtgaaggcgt
     8821 tcttgtcaca aatgcagctg gtggtatcgg ctacggccca ggtaccttga tggcaatcac
     8881 agaccatatc aatatgaccg gaaataaccc actaatcggt gaaaacttgg acgagtttgg
     8941 tccacgcttc cctgatatgt ctgatgccta tactaaggtt tatcgcaata aggcacatga
     9001 agtggctgaa aaaatgaaca tcaaactaga agatggtgtt tatatgggct taactggtcc
     9061 aacttatgag acaccagcag aaatccgtgc tttcaaagta ttaggagcag atgctgtcgg
     9121 catgtcaact gtgccagaag ttattgtggc tgctcattct ggacttaaag tacttggcat
     9181 ttcagccatc actaactttg cagctggttt ccaatcagaa ttgaaccacg aagaagttgt
     9241 tgaagtgact gaacatatta aagaagattt caaaggtctt gttaaagcta ttttagctga
     9301 gttgtaggac gaacaaaatc aactggagca ttattacagg aatgttattt tatgtcgtca
     9361 gtttggcaca tctgttcgca ataaaaaaat caaaaaataa tcacggggtg tgagttctat
     9421 gaatgttgaa ctcagattct agcttttcta actaacataa ccaacgaagg gaaagagacg
     9481 tattcggttt aaattaagca tggactcgaa catttcttcg tattaatttt taaataataa
     9541 aggaaagaga gttagtcctt tcttatttga actcgatttt tagctctctt cttctattca
     9601 atatcaatta tgaaaggaat ggggttgtat tcaattgaat acgggcggaa agctcggaaa
     9661 ctagataaac taacttttgt gctcacacat ggcgttagtt ccctaaattt cagttgcttt
     9721 ctgtccgccc tctgaccttc tacaaaataa aaggaaaggt agggctaact gtattcattg
     9781 aattgaatac gggcggagaa ctgtgtaaaa aagataaact gtctagcatc tgggatgcgt
     9841 cgtcagtttc ctatttttac tttgttcttt gtcgccttta atatcttaat aatgtctatc
     9901 catatttctg ccaaaaaagg tgatattgct gataaaattc ttctacctgg agaccctttg
     9961 cgcgcgaaat ttatcgctga aaatttccta gaagatgcag tgtgttttaa cgaagtgcgt
    10021 aacatgtttg gctacacagg aacttacaaa gggcgccgcg tttctgtcat gggaactggt
    10081 atgggcatgc cttcgatctc tatctatgct cgtgaattaa tcgttgatta cggtgtcaaa
    10141 acattgatcc gtgttggtac tgcgggtgcg attgacccag aagttcatgt gcgtgaattg
    10201 gtgcttgccc aagcagcagc aaccaactca aacattatcc gtaatgactt cccagaattt
    10261 gatttcccac aaattgctga ttttggttta cttgacaagg cttaccatat cgccagagaa
    10321 atgggagtaa caactcacgt tgggaatgtg ctttcttctg atgtctttta cactaacatg
    10381 cctgagcgta atatggctct tggtaaattg ggtgttaaag ccatcgaaat ggaagcagca
    10441 gctctttact atttagctgc tcagcaccat gtcaaagccc ttggaatcat gacgatctca
    10501 gataacttga atgatccaac cgaagatact acagctgaag agcgccaaac cactttcact
    10561 gatatgatga aggtcggctt ggaaacctta attgccaatg actaataatc aaacactaga
    10621 catccttttg gatgtctatg cttataatca cgcctttaga attgctaaag ccttgccaaa
    10681 tatccctaaa actgccctct atttactaga gatgttaaaa gagcgcagag aattgaacct
    10741 tgcctttctg gcagaacatg cagcagagaa tcggaccatt gaagaccagt accactgttc
    10801 attatggctt aaccaatcgc ttgaagatga gcagattgcc aattacattt tggatttaga
    10861 agttaaagta aaaaacggtg ctattattga ttttgtcagg tcagtgtcgc ctattcttta
    10921 tcggcttttt ctcagactaa tcacgtcaga aattccaaac ttcaaggctt atatttttga
    10981 tacaaagaat gaccaatatg atacctggca ttttcaggcc atgttggaat ctgatcacga
    11041 ggttttcaag gcttacctgt ctcaaaagca gtctcgcaat gtgacgacca aaagcttagc
    11101 agacatgttg acgttgacct ccttacctca ggaaatcaag gacttggttt ttttgttacg
    11161 acattttgaa aaggctgtcc gtaatcctct ggctcatttg attaagcctt ttgatgaaga
    11221 ggaactgcat cgcaccactc atttttcttc tcaggctttt ttggaaaaca ttatcacctt
    11281 ggcgactttt tctggtgtaa tctaccgacg tgagcctttt tactttgatg acatgaatgc
    11341 cattattaaa aaggagttga gcctttggag acaatctatt gtctgatatt tatcaaaaaa
    11401 cacgataact tgaccgatac aggtcttact accgtgtttt tttagtatga cgattgaaaa
    11461 agaaattaat caaaggttac ttcttcgaga aggtattcga taaaacgttc ccccattttg
    11521 gacaagttgg ctttttcatg cttgataaaa acaatgtcaa tttcgtcagg gacatctagc
    11581 gggatagcca caatctggtc accatttaga ttgctattta gaataccact ggcaacggtg
    11641 tagccatcta aaccaatcat taagttaaag agggtggcac ggtcactgac cacaattgat
    11701 ttgctgtggg gcatctggga catcatctct tctgaaaaat aaaaggagtt gtgaatccct
    11761 tggtcatagc tcaggtaagg aaaatctctc aagtcgtcca tgcttaatag gcttttagtt
    11821 gctagaggat ttgatttgct gacaaaaata tgaggctgtg ccttaaataa tggagaggcg
    11881 gtcaaatgat tgtcatcaaa taatttggtc aagacatctc ggttatagtc gttgataaag
    11941 agaacaccaa tttcagatcg aaagtttttg acatcatcaa tgatttccca agttcttgtc
    12001 tcgcgcaaaa agagttcata ccgagtcatg tcggtccgct tgaggagtga gacaaatgca
    12061 ttgactacga aggcataatg ttgagatgaa acgctaaaga gctctcggcc agtattgtgg
    12121 tttttatagc ggtcttctaa cagtgaggtt tgctctataa tttggcgagc ataagataaa
    12181 aattccaccc catcttttgt caaggtgatc cctttaggat ttcggttgaa aatggtaatg
    12241 cccatctcca tttccaaatc cttgaccgca ttggatagac ttggttgtgt gataaataat
    12301 tgcttagcag cttcattcat agagccgcac tcaacaattt tgataatata atgcagttgt
    12361 tgaattctca taagtacagt ctagctcaaa aaaaataaag acgcaagcac aaacgtcatc
    12421 atgggtttag aactttgaaa aagcgctgga gtcttttctc aatatggcct aggataaata
    12481 tgattcaatt ttgagagttg aatctatcaa tttcattgcc cttttatttt tcttgtgtta
    12541 tattaatagt attaacaaat aggtattttt ctaatcaaag ggtggtggtc gtgtgaatgt
    12601 tactgaacaa aatagtcatc aaatcttaat ccaaaagtta ttggtcagta tccactattt
    12661 gactcttttt cgagatgaac tgaagcttgt agaacgaact ccttctatac ttggagggga
    12721 atttccagct catttagtac agtctgagtt gggagatatt gttgcggcca ttgatacctt
    12781 ggatatgcag caacgcttga ttgagtctac cttttggtat gaagaatcag cttttaagtt
    12841 gatgaacaaa actttggata ttgtcgataa ttggattaaa ggagtggatc atctgataga
    12901 tttatgccag tccaaagaag tctttcaaat tattattgga gataaacgca ttcgagtttt
    12961 tggggtctta agtgatgttt tttcatcttt aaaagtgagt gctttgtcac ttaaggaagc
    13021 tcctattccg gatgtgctct atgaacatat ccagagggtt aatcttgaag aagaaacttt
    13081 tataaaatat taccaaagcc ctaaggtacc cacaggtgag tttgaataaa tgattgggta
    13141 aaaatgataa aatgagttga cgtaagtata caaaaaaaga tatagtagga aaaatgtgtt
    13201 caaataacaa aaagttttga catcttgttt taaaaaagct ataatagttt aaatttagac
    13261 acctttaagt gagtccagag aggcaaacaa ggtatacaag ataaaaaaag ggaattccct
    13321 tttagtttgc tgtggcctcg cttctttggt agcgaggctt tttggtgctt aatgagatat
    13381 tgacgcatta tagaaaggat aagttatgaa agaagaacgc ccaattattg ctttagactt
    13441 ttcatcattt gaggagacta aagcattttt agacttattt ccagcagaag aaaagctata
    13501 cgtgaaaatt ggtatggaat tatattatgc gcaaggacca gatattgttt ggtatatcaa
    13561 atcgttaggg cataatgtat ttttggattt aaaattacat gatattccaa atactgttcg
    13621 tgctgctatg gcagttctta aagaattaga tattgatatg gcaactgttc atgcagctgg
    13681 tggtgtagag atgctaaaag cagctcgaga aggactaggt caaggcccta ccttaattgc
    13741 ggtaacgcag ctaacttcaa ccagtgaaga ccaaatgcgt ggtgatcaaa atattcaaac
    13801 gagtctttta gagtctgttt tgcattacag caagggggca gctaaagctc agctagatgg
    13861 ggtggtttgt tcggcacaag aagtagaagc tatcaaggcg gtgacaccta cgggatttac
    13921 ttgcttaact cctggcattc gtcctaaagg cagtaatatt ggcgatcaaa aacgagtgat
    13981 gactccaaac caagcaagac gcattggaag tgattatatt gtggtagggc gaccaattac
    14041 ccaggcaaaa gacccagtgg ctgcttacca agccataaaa gctgagtggg caggctaaca
    14101 gataagatta ggaaaccaac acttgtctgt taaagaagaa aaaggagaat aagaaatgac
    14161 actagcaagc caaattgcaa ctcaattact tgatattaaa gctgtttatt taaagcctga
    14221 agaccctttt acgtgggcat ctggcattaa atcacctatt tacactgata atcgtgtcac
    14281 cctttcttat cctaagactc gtgatttaat tgagaatggg tttgtggaaa ctatcagggc
    14341 tcatttccca gaagttgagg tcatcgctgg tacagctaca gcaggtattc ctcacggtgc
    14401 cattatagca gataaaatga ctcttccttt tgcttatatt cgcagtaagc caaaagatca
    14461 tggagcaggc aaccagattg aggggcgtgt gcttaaaggt caaaaaatgg ttatcattga
    14521 agatttgatt tcaacaggtg gttcggtact agatgcagcc gcagcagcca gtcgtgaggg
    14581 agctgacgtt ctgggagttg ttgcgatttt cacttatgag ttaccaaaag ctagtcagaa
    14641 ttttaaagaa gctggtatca agttgattac gctttctaat tatactgagc taattgcagt
    14701 tgcaaagttg caaggctata ttactaatga tggtttacat ttacttagaa aatttaaaga
    14761 agaccaggta aactggcaac aataaggaac tatcagccag gtttattttt aatgaaaaaa
    14821 tctctttagc cccaattcaa aatgttatgt tttgattgtt ttgtctacac tccttacaca
    14881 tcacattcta atttctaacc ttttaatggt ggttttcttt tatttgtgtt ttaataaaaa
    14941 agaatgtttt aggattcata tcttagaaag gaagagtagc tatgacttat caagatgcga
    15001 cggctatggc tattgctgtt cagactggtc agaccacacc actagaatta gtaacccagg
    15061 ctatttataa ggctaaaaag ttgaacccta ccttaaatgc tattacctca gaacgctttg
    15121 aagcagccct agaagaagcc aaacaaaggg atttttcagg taagcctttt gcaggagttc
    15181 ccattttttt gaaagatttg ggacaagaat taaaaggtca ctcatcaacc tcaggttcca
    15241 gattgtttaa agagtatcaa gcgactaaaa cggatttatt tgtgaaaaga ttagaagctt
    15301 taggctttat tattttaggg cgctccaaca cgcctgaatt tggctttaaa aatattagcg
    15361 atagcagttt gcacggacca gtgaatttac caaaggataa tacacgaaat gctggtggct
    15421 catctggggg agctgctgct ctagtgtcat caggaattag tgcactagca actgctagtg
    15481 atggtggtgg ttctattcga attccagcct cgtttaatgg cttaattggg ctcaaaccta
    15541 gccgtgggcg catgcctgtc ggacctggtt cttatcgaag ttggcaagga gcctcagttc
    15601 attttgcctt gaccaaatcc gttagagata ctagaaatct actctactat ttacagatgg
    15661 aacaaatgga aagccccttc cccctagcca ccttaacaaa agatagtatt tatcaatcgc
    15721 tacaacgtcc cttgacaatt gctttttatc aacggttaag tgacggtagc ccagtatctt
    15781 tagatactgc aaaagcttta agacaagcag taacttggct aagagaacaa gggcatcagc
    15841 tagttgaatt ggaagagttt cctgtaaata tgacagaagt gattcgtcat tattatatta
    15901 tgaatagtgt ggaaacggct gctatgtttg ctgatattga agacactttt ggacgtccga
    15961 cgaccaaaga cgatatggaa accatgacct gggctattta ccaatcaggt aaagacatcc
    16021 cagcttggcg ttactcacag gtccttcaaa aatgggatac gtacagtgca accatggcta
    16081 gttttcatga gacttatgac ctgttgttga cgttcacaac caacacacca gctcctaagc
    16141 acggagaact tgccccagat tcgaaactca tggctaactt ggctcaagct gaaattttca
    16201 gcagtgaaga gcaattcaat ttggtcgaaa ccatgtttgg taagagtctg gctattaatc
    16261 cttacacagc tctgcctaat ctaactggcc agccagctat tagtttacct acttacgaaa
    16321 ctaaggaagg gctcccaatg ggcattcaac taattgcagc caaaggtaga gaggacctat
    16381 tattaggaat tgcagagcag tttgaggcag caggattatt gaagattcct caataataat
    16441 cttataaaac agtttaacta ttatagatta actttttaaa gagattgagc gctcactgat
    16501 aacacaactt aatcaaaatg ttatactatt cttatcttaa taaaggagtt actatgaaga
    16561 aatcagttac attactgtct atcggacttg ccagcctttt attggcagca tgtgtgccac
    16621 atcaatctca aaaatcaagt tgggacacta tcaaagaaaa aggggtgtta aaagtagcta
    16681 ccccaggaac ctatcagcca acttcttttt acaacgataa taatgagtta gtaggttacg
    16741 aagtagatat ggtcaaagaa atcggtaaac gacttaacat taaagtcaag tttgttgaaa
    16801 caggatttga ccaagccttt acctcagttg atagtggtcg agtggatatt tctttgaaca
    16861 actttgacat taccccaaaa cgtcagaaaa aatacaatat ctctacgcct tataaatacg
    16921 gggtaggagg catgattgtc cgtgctgatg gcagctcaaa catggctaaa aaagatctta
    16981 gcgactggaa aggaaaaaaa gcagccggcg cttctggaac agaatacatg aaagtagcgc
    17041 aaaaacaggg agctgaactg gtgacctacg ataatgttac aggagatgtt tatctaaacg
    17101 atgtggctaa cggtcgaaca gatttcattc caaatgatta cccagctcaa aaattatttg
    17161 tggattacat gttatctcaa aatccaaatc taaatgtcaa aatgagcgat gttcagtaca
    17221 acccaaccga acaaggaatt gttatgaaca aaaaagacga tagcctcaag aaaaaaatag
    17281 atgctgttat taaagacatg ataaaagatg gtagcttgaa gaaaatctct gaaacctact
    17341 atgctggtca agatttgaca aaaccttttg gcaaagacaa aaaaattccc gtcattgata
    17401 cgaaagacgt taactaatac ttgatgttaa aggagtccta accacatgat taatatccca
    17461 ttaatgaaag atagtttagg atttgtgtta tcgggattac cttataccct tggtatttcg
    17521 ttgctcagtt tttttacggg tctgttttta ggtttaggcc tagcccttct gggaaggtca
    17581 cgtcagccgt tgattcatta tcttgttaga gcgtacatct ctattatgcg aggtgtgccg
    17641 atgatcgtgg tgctctttgt tctttatttc gggttgcctt attatggttt agaattgcca
    17701 gctttacttt gcgcttatct tggtttttct atggttagcg ctgcctatat ttctgaagtt
    17761 tttcgctctt ctatagaagc tattgacaag ggacagtggg aagcagctaa ggctttaggg
    17821 ttgccatatg ctcttatggt taagaaaatt attcttcctc aagcttttcg aattgcagtt
    17881 cctcctctag gcaatgtcat tattgatatg gttaaaagtt cgtcgctagc tgccatgatt
    17941 accgtaccag atatttttca aaatgccaaa attattggcg gtagagagtg ggattacatg
    18001 tccatgtata ttttagtagc ctttatctat tggcttattg cttttttgtt agaacgttac
    18061 caagaattct tagaaaataa gctagcactt gtttaatatc ctgtaaaaaa cgaatattaa
    18121 ccctggaaat atcatatttt cagggtcttt ctatttaaaa tgtggtaaac tagatagaaa
    18181 aggacatcgt atttaactta gaaactgacg tgattagaaa ggaatcttat ggctcattca
    18241 atttggcatg agaaaatcaa atcatttttg ccggagcatt actatggtcg catcaatcac
    18301 tttttagatg aagcctatgc ttccggtctt gtctatcctc cacgagaaaa tgtctttaaa
    18361 gccttacaag tcactccttt ggaagaaacc aaagtgttga ttttaggaca agacccttat
    18421 catggcccca aacaggccca gggcttatca ttttcagttc cagaagagat ttctgctccg
    18481 ccatccctta ttaatatttt aaaagaatta gcagatgaca ttggtcctcg tgaccatcat
    18541 gatttaagca cttgggctag tcaaggggtt ctgcttttga atgcttgctt aacagtgcca
    18601 gcaggacagg ctaatgggca tgcaggctta atatgggagc catttacaga cgctgttatt
    18661 aaagtgctga atgagaaaga cagccctgta gttttcattt tgtggggagc ttatgcaagg
    18721 aagaaaaaag ccttcattac taatccaaag caccacatca tcgagagctc tcatccaagc
    18781 cctttgtcat cttatcgtgg cttttttggc agcaaaccct tttcaagaac caacgctatt
    18841 ttagaaaaag agggcatgac tggcgtagat tggctaaaat aagccagcca tttcaactaa
    18901 atagcttaag ctagacattt tgataccttt aataagtgaa atgagtgcag tagatttttc
    18961 ctattaaaga acgtaaggtc ttatggttaa aacagataaa taaaggagaa aacatgatac
    19021 tcatcaaaaa tggacgcgtt atggacccga aatcgcagag agatcaagtg gcagatgtct
    19081 tgattgatgg taaacagatt gtaaagatag cttcagctat tgaatgccaa gaagctcaag
    19141 tgattgatgc tagtggtctt attgttgccc cgggtttggt cgatattcat gtgcatttta
    19201 gagaacccgg tcaaacgcac aaagaagata ttcacacggg agccttggca gcagcagcag
    19261 gtggtgtgac tacggttgtc atgatggcta ataccaatcc tgtcatttca gatgtcgaaa
    19321 ctttacagga agtgctagct agcgcagcta aagaaaagat tcatatttac accaatgcca
    19381 gtgtcaccca agcctttaat ggaaaagacg tgactgattt taaagctttg ttggaagcag
    19441 gagcagtaag cttttcagat gatggtattc ccttagaaag ttctaaagtt ttaaaagaag
    19501 cctttgattt ggctaatgcc aaccaaactt tcatttcttt gcatgaggaa gatcctcagt
    19561 taaatggggt tcttggtttt aatgaaggta ttgctgagga gcattttcat ttttgtgggg
    19621 caactggtgt agcagaatat agtatgattg caagagatgt catgattgct tatgacaggc
    19681 aagctcatgt tcatatccaa catttatcta aagcagaatc ggttcaagta gtggcttttg
    19741 ctcagcagtt gggtgctaag gtaactgctg aagtgtcccc acaacatttt tcaacaactg
    19801 aagatctctt attgatcgca ggtaccagcg ccaagatgaa tcctcccctt cgtacacaaa
    19861 gagatcgctt agctgtcata gaaggcttga aatcgggtgt tatcacagtc attgccactg
    19921 atcatgctcc tcatcacaag gatgaaaaag ctgtggatga tatgactaaa gccccatctg
    19981 gtatgacagg acttgaaact tctttgtcat taggtttgac gcatttggtt gaaccaggtc
    20041 atcttacact tatgtcacta ttagaaaaaa tgacgcttaa tccagctttg ctttatggtt
    20101 ttgatgcggg ttatttggca gaaaatggtc cagcagattt ggttattttt gcagacaagc
    20161 aagaacgtct gatcactgag aattttgctt ctaaagctag taattcccca tttattggta
    20221 acaaactcaa aggtgtcgtg aaatacacta ttgcagacgg agaggttgtt taccctaatt
    20281 aacaaatgag ttaaaacaaa aaagcttgac tttcagagaa agtcaggctt ttagtaaatt
    20341 tattttttag gcacttgttt gcttaaattt agcccccaag gtattagatt ttcagtatga
    20401 tgtttgatac gactaatgtt atctttgtgt cttataataa taatgaacgc aagtaatatc
    20461 acaataaaag ttaaaaagta gtcataattt ggtaaaagaa aatgaatggc aggaaatgtt
    20521 aaaacagata acacaccaac gatagctgaa accacactag ctaaagatat catactaaat
    20581 aaatagagaa ctaaaacaaa gatagatgct aaaaaaaaga gatataacgg agcaaagcct
    20641 agcaatacac cagcacttgt tgctacggcc ttaccacctt taaagttggc aaaaatagga
    20701 aaagtatgcc ctaaaactgc gaaaaagccg atagcaatgg atgaaattga agtcatacca
    20761 aaaataattg gtaacaatat tgaaagtgtc cctttaaaca tatcaatagc taaggtagct
    20821 gttcctgcct tgacacctaa aatccgaaaa gtatttgtgg ttccagtatt tcctgatcca
    20881 tgctctcgta agttgatgtg gtaaaagtac tgtccaatcc atagtccagt tggaatagaa
    20941 ccaagtaaat aggcaatggt aataaaaagt agtaatttca taatccttat tataacatat
    21001 tcatagattg gagaactaga tctggaaaag aattcggaaa aaattagcaa attattttgc
    21061 aaaattggta aaaaacttgt aagataaaaa agatgaaact gtctggaggt cggtgttgac
    21121 taagaaagaa attacaatta ataattataa tgacgatgct atccaagtcc tagaagggtt
    21181 agatgctgtt cgcaagcgtc cagggatgta tatcggttca acagatgcta cgggattgca
    21241 ccacctgatt tgggaaattg ttgataatgc tgtcgatgag gccttgtctg gttttggaga
    21301 tgatattaag gttgttatca ataaagatgg ctcggtcagt gtggcagata gcggacgtgg
    21361 aatgccaaca ggccagcatg ccatggggat tcccaccgtt caagttattt ttacgattct
    21421 tcatgcaggt ggtaaatttg gtcagggtgg ctacaaaacg tcaggtggtt tgcacggtgt
    21481 tggctcctct gttgtcaatg ctttgtctgc ctggttagaa gtcgaaatca caagagacgg
    21541 gtcagtgtat cgtcagcgct ttgaaaatgg tgggaaacct gttacaaccc ttaaaaaagt
    21601 tggcacagct cctaagtcta aatcaggaac ggttgtaacc tttatgcctg atgataagat
    21661 tttttcaact attgacttta agttcaatac catttcagaa cgattgaaag aatctgcttt
    21721 tcttttgaaa aatgtcaaga tgagcttgac agatcttcgt ggagatgacc cgattattga
    21781 agagtttcat tatgaaaatg gggttcaaga tttcgtcgaa tacctcaatg aagataagga
    21841 aaccttgaca cctgttattt acatggaagg tcaagaccaa gactttcaag tcgaggttgc
    21901 tttgcagtat aacgatggtt tctccgacaa tatcttatcc tttgtaaaca atgtgcgcac
    21961 caaagatggt ggaagccatg aaacgggact aaagtcagct attaccaaag cgatgaatga
    22021 ctatgctcgt aaaaccaatc tcttaaaaga aaaggataaa aatctagagg gctcagatta
    22081 tcgagaagga ctctcagcag tattatctat cttagttcct gagcagcact tgcaatttga
    22141 aggacagacc aaagacaaat tgggaagtcc cttagctaga cctattgtag agagcattgt
    22201 ttctgaaaaa ttaaccttct ttttactcga aaatggagaa gtagcttctc atctagttcg
    22261 caaagccatt aaagctagag atgctcgcga agctgctcga aaagcgcgtg atgactcacg
    22321 taatggtaag aaaaacaaaa aagacaaagg cttgttgtcg ggaaaattaa ccccagctca
    22381 gtccaaaaat gccaagaaaa atgaattgta tctggtcgaa ggagattctg cgggaggttc
    22441 agccaaacaa ggacgagacc gcaaatttca ggctatttta ccattacgtg gcaaagtttt
    22501 aaataccgaa aaagctaaga tggctgagat cttgaaaaat gaagaaatta acactatggt
    22561 ttataccatt ggagctggag tgggagctga ctttaacctc gaggatatca actatgataa
    22621 gattattatc atgaccgatg ctgataccga tggggctcat attcagactc ttttgctgac
    22681 tttcttttac cgttatatgc gaccgttggt ggaagcaggt cacgtttata ttgcgcttcc
    22741 cccgctttat aaaatgtcaa aaggtaaagg taaaacagag aaagtgtcct acgcttggac
    22801 agatggtgaa ttagaagatt tacgtaagga atttggtaaa ggagccattc ttcaacgcta
    22861 taaagggcta ggtgaaatga acgccaacca attgtgggaa accaccatgg atcctgaaac
    22921 cagaaccctt attcgtgtta ctattgatga tttagcaaga gcagaacgac gcgtttctgt
    22981 tttgatgggt gacaaagccg ctccacgccg tcagtggatc gaggacaacg tcaagtttac
    23041 cttagaagaa aatacggtgt tttagtcata caagtttctc acagataatt acaagtgcta
    23101 aagacgattg ttttttaggt aattaataaa taatgaaaaa gaaagctatt tgaatatgtc
    23161 aaacattcaa aacatgtccc ttgaggatat tatgggagaa cgcttcggcc gttattccaa
    23221 gtatattatt caggaacggg cacttcctga tattcgagat ggattgaaac ccgttcagcg
    23281 ccgcattctt tattcgatga ataaggatgg taatactttt gaaaaaggtt accgtaaatc
    23341 agccaaatca gttggtaata tcatggggaa tttccacccg catggggatt cctctattta
    23401 tgatgccatg gtacggatga gtcaagattg gaagaaccgt gaaattcttg tggaaatgca
    23461 cggaaataat ggttcaatgg atggcgatcc gcctgcggct atgcgttata cagaagctcg
    23521 cttgtctgaa attgcgggtt atcttcttca agacattgag aaaaatacgg tctcttttgc
    23581 gtggaacttt gatgacacag aaaaagaacc caccgtttta ccagcagctt ttcctaactt
    23641 acttgtcaat gggtcttctg gtatttccgc aggttatgcg acagatattc caccgcacaa
    23701 tttgtcagaa gtgattgatg ccgttgttta catgattgac catcccaagg ctagcttaga
    23761 gaaattaatg gagtttttgc ctgggccaga tttcccgaca ggaggcatta tccaaggagc
    23821 tgacgaaatc aaaaaagcct acgaaacagg taagggacgt gtcgttgttc gctctaggac
    23881 ggaaattgag gaacttaaag gtggtaaaca acaaattatt gtcactgaga ttccttatga
    23941 agttaacaaa gcagtcttgg tcaaaaagat tgacgatgtt cgtgttaaca ataaagtccc
    24001 aggcatcgta gaagtacgtg atgaatctga tcgcacaggt cttcgcatag ctattgagtt
    24061 gaaaaaagag gctgatagcc aaaccatttt gaattatttg ttgaaataca cagatcttca
    24121 agttaattac aatttcaata tggttgctat tgatcacttt acgccacgcc aagtaggtct
    24181 tcaaaaaatc ttatcaagct atatcagcca ccgcaaagat attattattg agcggtctaa
    24241 attcgataaa gccaaagctg aaaaacgcct ccacattgtt gaaggattga ttcgtgtctt
    24301 gtccatctta gatgagatta ttgctttgat tagatcgtct gacaataagg ctgatgctaa
    24361 agaaaatctg aaagtcagct atgatttctc tgaggaacaa gcagaagcga ttgtaacctt
    24421 gcagctttat cgtctaacta ataccgatat tgttactctc caaaatgaag aaaatgattt
    24481 aagagactta atcacgaccc tttccgctat tatcggtgac gaagcaacca tgtataacgt
    24541 catgaaacgt gaattaagag aagtgaaaaa gaaattcgcc aatcctcgtt tatcagagtt
    24601 acaagcagaa agtcaaatca ttgagattga cactgccagc ttgattgcag aggaagaaac
    24661 ttttgttagt gtgacacggg gcggatacct caaaagaacc agcccacgat ccttcaatgc
    24721 gtctagtttg gaagaagttg gcaagagaga tgatgacgaa ctcatcttcg ttaaacaggc
    24781 caaaacaaca gaacaccttt tgttatttac aactttaggc aatgtcattt accggccaat
    24841 ccatgaattg accgatttac gttggaagga tatcggtgaa catttatcac aaaccatttc
    24901 aaacttcgcg acagaagaag agattctcta cgctgatatt gtgacttcct ttgaccaggg
    24961 cttgtatgtg gctgtcacac aaaatggttt tatcaaacgc tttgatcgta aagaactaag
    25021 tccttggcga acttataaat ctaaatcaac caaatatgtg aagctaaagg atgacaaaga
    25081 ccgcgtggtt accttgtcac cagttattat ggaagacctc ctattagtga ctaaaaatgg
    25141 ttatgctttg cgattctcca gtcaggaagt gcctattcaa gggttgaaat ctgctggtgt
    25201 taaaggcatt aacttgaaaa atgatgacag ccttgcctca gcctttgctg tgacaagtaa
    25261 ctctttcttt gtcttaactc agaggggttc tctcaaacgg atggctgtcg atgatattcc
    25321 tcagacaagt cgtgccaatc gtggactatt ggtcctacga gagttaaaaa ccaaacctca
    25381 tagagttttt ctggccggag gcgttcgatc agatacttca gctgagcagt ttgatttgtt
    25441 cactgatata cctgaagaag aaactaatca acaaatgctt gaagtcatta gtaagactgg
    25501 tcaaacctac gagattgctt tagaaacgct ttcgttatcg gaaagaacca gcaatggctc
    25561 ctttatttca gacactattt cggatcaaga agtactggta gctagaacac gttaaaaaga
    25621 gtgaaaactc tttttaattt tatggtaaat ttagaatatt aatgcaaaag agtataataa
    25681 acttgaaaat tattgaaaaa aagttacaat agaaaaaagc agaaaagagg tacgatgatg
    25741 acaatagcaa ttgattggga caacctagga tttgaatatc ataagttgcc atttcgttac
    25801 atttcttatt acaaaaatgg tcaatgggat aaaggtcaat taacagaaga tgccacctta
    25861 catatctcag aaagcgctcc agcgcttcat tatgggcaac aagcttttga aggtttaaag
    25921 gcttatcgca ccaaagatgg ctctattcaa ctatttagac cagaccgtaa tgcagtgcgt
    25981 ttacaagcca cagcagaccg cttgttgatg ccacaagtat caacagagca atttattgat
    26041 gcagctaagc aagtggttaa agccaatgaa gactttgtac caccttacgg aacaggtgca
    26101 acgctttacc tgagaccgtt attaattgga gttggagata ttattggggt taaaccagcc
    26161 gaagaatata ttttcaccat ttttgccatg ccagtaggaa actatttcaa aggtggactt
    26221 gctccgacta attttattgt ttctgaagcg tttgaccgcg ccgctcctta cggaacaggt
    26281 gctgctaagg tgggaggaaa ctatgcagga agtttgctac caggtaaggc cgctaaatca
    26341 gcaggctttt ctgatgtgat ttacttagat ccagcaaccc atactaaaat tgaagaagtc
    26401 ggagctgcaa acttttttgg cattactgca aataatgaat ttgttacgcc acttagtcca
    26461 tctatcttgc catctattac gaagtattca ctcttacaac tagctgaaga aagacttggt
    26521 atgacagtaa ttgagggtga tgttccaatt aatgaattgg ataaatttgt ggaagcagga
    26581 gcttgtggaa cagcagctgt tatctctcca attggcggta tccagtacaa ggataactta
    26641 catgtctttt acagtgaaac agaagttggt cctgtgacac gccgtttata cgatgagttg
    26701 gtcggcattc aatttgggga tattgaagca ccagaaggtt ggattgtaaa agtagattaa
    26761 aatagagctt gctcttgcaa gcttttttga ttttgtgtaa aatagacaaa gtgaggtaaa
    26821 gtgatgagta aaaaagataa aaaaattgaa atccaactga ttgatcataa agttatggtt
    26881 aatgagacta agattgatgg ctatcaatta caaattggta aacgtgtggt tggagaaatt
    26941 gcagaacttg atgagaaatt tgctgtctta aaaaatgatg gagtagattg cttcttcaaa
    27001 acgctcgaac aagcggttga aaatatcatt gaaaactaca atttgaacca ttaaaattag
    27061 acaaaaacac ttgccagctt acaaaaacta tgatagaata gtttttgttg ttacggaaag
    27121 atagcgaaga gg
//
LOCUS       DAUGSW010000021        25788 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUGSW010000021 DAUGSW010000000
VERSION     DAUGSW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25788
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.021"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            192..1475
                     /locus_tag="VIB18_001055"
     CDS             192..1475
                     /locus_tag="VIB18_001055"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEQ8766070.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSGEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            1692..2267
                     /locus_tag="VIB18_001056"
     CDS             1692..2267
                     /locus_tag="VIB18_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEQ8766071.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            2524..4128
                     /locus_tag="VIB18_001057"
     CDS             2524..4128
                     /locus_tag="VIB18_001057"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEQ8766072.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQYSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNRN"
     gene            4296..5222
                     /locus_tag="VIB18_001058"
     CDS             4296..5222
                     /locus_tag="VIB18_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8766073.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLVKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            5276..5361
                     /locus_tag="VIB18_001059"
     tRNA            5276..5361
                     /locus_tag="VIB18_001059"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5310..5312,aa:Leu,seq:aag)
     gene            5569..6450
                     /locus_tag="VIB18_001060"
     CDS             5569..6450
                     /locus_tag="VIB18_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEQ8766074.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEVKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            6832..7020
                     /locus_tag="VIB18_001061"
     CDS             6832..7020
                     /locus_tag="VIB18_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEQ8766075.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            7172..7537
                     /locus_tag="VIB18_001062"
     CDS             7172..7537
                     /locus_tag="VIB18_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8766076.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            7537..9201
                     /locus_tag="VIB18_001063"
     CDS             7537..9201
                     /locus_tag="VIB18_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEQ8766077.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKEFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATCTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            9438..10328
                     /locus_tag="VIB18_001064"
     CDS             9438..10328
                     /locus_tag="VIB18_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEQ8766078.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     VAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            10558..11412
                     /locus_tag="VIB18_001065"
     CDS             10558..11412
                     /locus_tag="VIB18_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEQ8766079.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYFQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            11605..12801
                     /locus_tag="VIB18_001066"
     CDS             11605..12801
                     /locus_tag="VIB18_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEQ8766080.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            13064..13615
                     /locus_tag="VIB18_001067"
     CDS             13064..13615
                     /locus_tag="VIB18_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8766081.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            13682..14053
                     /locus_tag="VIB18_001068"
     CDS             13682..14053
                     /locus_tag="VIB18_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8766082.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            14091..15437
                     /gene="glnA"
                     /locus_tag="VIB18_001069"
     CDS             14091..15437
                     /gene="glnA"
                     /locus_tag="VIB18_001069"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEQ8766083.1"
                     /translation="MAITVADIRHEVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(15665..17347)
                     /locus_tag="VIB18_001070"
     CDS             complement(15665..17347)
                     /locus_tag="VIB18_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8766084.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWRESTVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(17349..17579)
                     /locus_tag="VIB18_001071"
     CDS             complement(17349..17579)
                     /locus_tag="VIB18_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEQ8766085.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            17863..18561
                     /gene="tsaB"
                     /locus_tag="VIB18_001072"
     CDS             17863..18561
                     /gene="tsaB"
                     /locus_tag="VIB18_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEQ8766086.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHASLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            18533..18988
                     /gene="rimI"
                     /locus_tag="VIB18_001073"
     CDS             18533..18988
                     /gene="rimI"
                     /locus_tag="VIB18_001073"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEQ8766087.1"
                     /translation="MIVTMLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            18978..20006
                     /gene="tsaD"
                     /locus_tag="VIB18_001074"
     CDS             18978..20006
                     /gene="tsaD"
                     /locus_tag="VIB18_001074"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEQ8766088.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLVKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(20177..20446)
                     /gene="rpsN"
                     /locus_tag="VIB18_001075"
     CDS             complement(20177..20446)
                     /gene="rpsN"
                     /locus_tag="VIB18_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEQ8766089.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(20682..21425)
                     /locus_tag="VIB18_001076"
     CDS             complement(20682..21425)
                     /locus_tag="VIB18_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8766090.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSC"
     gene            21665..22444
                     /gene="udp"
                     /locus_tag="VIB18_001077"
     CDS             21665..22444
                     /gene="udp"
                     /locus_tag="VIB18_001077"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEQ8766091.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            22465..23667
                     /locus_tag="VIB18_001078"
     CDS             22465..23667
                     /locus_tag="VIB18_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEQ8766092.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            23697..24368
                     /gene="deoC"
                     /locus_tag="VIB18_001079"
     CDS             23697..24368
                     /gene="deoC"
                     /locus_tag="VIB18_001079"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEQ8766093.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIKNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(24463..25632)
                     /locus_tag="VIB18_001080"
     CDS             complement(24463..25632)
                     /locus_tag="VIB18_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8766094.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSADQTFTCQKLIV
                     TTGGKSYPSTGSTGFGYDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNTLKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
BASE COUNT         8183 a         4286 c         5459 g         7860 t
ORIGIN      
        1 ttgaaaatag tcagttagta agcgaaaaag tctaacatta acctttataa attgaaaata
       61 actgttagta gactaatgac aggtagatac tcttaatagc gcgtttgatt tcacgcataa
      121 aaagctttaa aaacgcttta aattatgata aaatgaactg tatcgaaatt attttaagga
      181 gaaatgactt aatgtctaca tcatttgaaa acaaagctac aaatcgtggc gtgattacat
      241 ttacaatcag tcaagataaa ataaaaccag ctcttgataa agcttttaat aaaatcaaaa
      301 aagacttaaa tgcaccaggt ttccgtaaag gacacatgcc tcgtccagtc ttcaaccaaa
      361 aatttggtga agaagttctt tatgaagatg ctttgaatat tgtattgcca gaagcttatg
      421 aagcagctgt gacggaactt ggtcttgatg tggttgcaca accaaaaatc gatgttgtgt
      481 caatggaaaa agggaaagag tggacacttt ctgctgaagt tgtgacaaaa cctgaagtga
      541 aacttggtga ttacaaaaac ctagttgtag aagttgatgc ttcaaaagaa gtttcagatg
      601 aagacgtgga tgctaaaatt gagcgcgaac gtcaaaacct tgcggaactc attattaaag
      661 acggtgaagc agctcaaggt gacactgttg tgattgactt tgttggttca gttgatggtg
      721 ttgagtttga tggcggtaaa ggagataact tctctcttga acttggttca ggacaattta
      781 tcccaggttt tgaagatcaa ctagttggtg ctaaagctgg cgatgaagta gaagttaatg
      841 tcacattccc agaatcttac caagcagaag atcttgcagg taaagccgct aaatttatga
      901 caactattca cgaagtcaaa acaaaagaag taccagagct tgatgatgag cttgcaaaag
      961 atattgatga agatgttgac acacttgaag acttaaaagt aaaatatcgt aaagaacttg
     1021 aagcagctca agaaactgct tatgatgatg ctgttgaagg agctgcgatt gaattagcag
     1081 ttgcaaatgc tgaaattgtt gatttacccg aagaaatgat tcatgaagaa gtcaaccgtt
     1141 cagtgaatga atttatgggc aacatgcaac gtcaaggaat ctcacctgaa atgtacttcc
     1201 aattgactgg tacaactcaa gaagatttac ataaccaata ttcaggtgaa gctgacaaac
     1261 gtgttaaaac aaaccttgtt attgaagcaa ttgctaaagc agaaggtttt gaagcaacag
     1321 atagtgaaat tgaacaagaa attaatgacc ttgcaacaga atataacatg ccagctgacc
     1381 aagttcgttc tcttctttca gcagatatgt tgaaacatga tattgcaatg aaaaaagcag
     1441 ttgaagtgat tacaagcaca gcaagcgtta agtaatctta ttaaggaaca aaacgtacaa
     1501 gccggattag aacgtctttc tagtctggtt tttctttttc taaagaaata ataaggaatt
     1561 agttagacgt tattttaatg aattagcttt aaagatttgt caagaagaag ttatatgagt
     1621 tgataaaagt tttgacgaat tacttttttt agcgtaaaat ggtagagaat gataaaataa
     1681 ggagaactgc cttgaaatta gacgtatttg caggacaaga aaaaagcgag ctttccatga
     1741 ttgaagtggc gcgtgccatt ttggaagaac gcggtcgcga caatgagatg tactttagcg
     1801 atttagtcaa tgagattcaa aattacttag gaaaatctga tgcaggtatt cgtcatgcat
     1861 taccattttt ctatactgac ttaaatacgg atggctcatt tattcctcta ggtgaaaaca
     1921 aatggggact tcgttcgtgg tatgctattg atgaaattga tgaagaaatt attactctag
     1981 aagaagatga agatggcgca caaaaacgta agaaaaaacg cgttaatgct ttcatggatg
     2041 gagatgaaga cgctattgat tatagagatg atgatccaga agatgaagat ttcacagaag
     2101 aatcagctga ggttgaatat gatgaagaag atccagatga tgaaaaatca gaagtggagt
     2161 catatgattc agaattgaat gaaattatcc ctgaagatga ttttgaagaa gttgatatca
     2221 atgaagaaga cgaagaagat gaagaagatg aagaaccagt tctctaatgt ctttagttca
     2281 gaaataaaaa tgtgattatc atttgacaaa ttgtctatta tagtttatat tattattcgg
     2341 gcacctcttt aagaggtcag gcaaaagctc tctagttaat agggggctat ttttgttttc
     2401 tagaataatg ccagtttgcc tctatattta gaaaactaag gtgataccta accaatgtgg
     2461 aaccaactaa tagggaatta acaagaaagc aatgctttta ttcagcttat ataaaggagt
     2521 actatgacga aatacatttt tgtaactggt ggtgttgtat catcaattgg caaaggaatt
     2581 gttgcggcaa gtcttggccg attgttaaaa aatcgtggac ttaaggtgac gattcaaaaa
     2641 tttgatcctt atattaatat tgatccaggg acgatgagcc cctatcagca tggagaagta
     2701 tatgtgacag atgacggtgc tgaaaccgac ttggatttgg gtcactatga acgttttatt
     2761 gatatcaatc ttaataaata ttccaatgtt acaacaggta aaatttatag tgaagtcctt
     2821 cgtaaagaac gtaaaggtga gtaccttgga gcgactgttc aggtgattcc tcatatcaca
     2881 gatgccctta aagaaaaaat caaacgcgca gcttcaacaa cggactctga tgtaattatt
     2941 actgaggtcg gggggactgt tggcgatatt gaaagtttac cgttcttaga agctcttcgt
     3001 cagatgaaag ctgatgttgg ttctgaaaat gtgatgtata ttcacaccac cttgttgcca
     3061 tatttaaagg cagcgggtga aatgaaaact aagccaacgc aatattccgt taaagaattg
     3121 cgtggtttag ggattcaacc gaatatgttg gttattcgta cggaagagcc agttgagcag
     3181 gggattaaaa ataaattggc tcagttctgt gatgtgaatt cagaagctgt tatcgagtca
     3241 cgtgatgtag aacacttgta tcaaattcca ttgaacttgc aagcccaatc aatggatcag
     3301 attgtttgtg atcatttgaa attgaatgcg ccacaagctg atatgactga gtggtcagct
     3361 atggttgaca aggtgatgaa tttaagaaaa acaacaaaaa ttgccttggt tggtaaatat
     3421 gtggaattgc cagatgccta cttatctgtt gtggaagcct tgaaacattc tggttatgcc
     3481 aatgataccg caattgacct aaaatgggtc aatgctaacg atgtgacggt ggataatgca
     3541 gctgacttgt tgggagatgc ggatgggatt attgtaccag gtggttttgg tcaacgtggt
     3601 acagaaggca agatccaagc gattcgctat gcccgcgaaa atgatgtgcc aatgcttggt
     3661 atctgtcttg gcatgcagtt gacttgtgtt gaatttgctc gtcatgtcct caatatggaa
     3721 ggtgcaaact cttttgaatt agagccaagt actaaatacc ccatcattga tatcatgcgt
     3781 gatcaaattg atattgaaga tatgggaggt acgcttcgtc tgggattgta cccatgtaaa
     3841 ttgaaaccag gttcaaaagc agcaatggct tacaataatc aagaggtggt gcaacgtcgt
     3901 catcgtcacc gttatgagtt caacaacaaa ttccgtccag aatttgaagc agctggtttt
     3961 gttttctcag gggtatcacc tgacaaccgc ttagttgaaa ttgtagaatt gaaagagaaa
     4021 aaattctttg tagcagctca ataccaccca gaattgcaaa gccgtccaaa tcgtcctgag
     4081 gagctataca ccgcttttgt tacagctgct attaaaaata ggaattagtg gttttaaggg
     4141 taagtttgtg gcattctact tggctggcag atactgataa agattactag ctattagagg
     4201 gatcttttct ataaaaatag cattagaaaa agaaaaacgt gatattttta ggttagcact
     4261 ttctttttca gtcatttttt tgtaaaatac ttggtatgaa aactattcga atagcaaagt
     4321 atttaggaat tctattcctt ttgataactc ttattagcgt aggtgctagt ttttatttct
     4381 ttcatgttgc acaaataaga gaagagaaat cgtttattaa taataagaaa cggagtacga
     4441 ataatccatt atacccagct gaacagtctt ttgacgcttt accttacgaa aaacgtcaac
     4501 taacaaatcg tgggttaaaa caagtggggt ggtacttacc agctgctcaa aaaacaaaaa
     4561 agacagctat tgttgttcat ggttttacga atgacaaaga agatatgaag ccatatgcca
     4621 tgctttttca tgatttgggc tataatgtct taatgccaga caatgaggcc catggggaaa
     4681 gtgaaggaaa cttgattggt tatggctgga atgaccgcct taatgtcatg gcttggacag
     4741 accaactggt taaggaaaac cctgaaagcc aaatcacact ctttggctta tctatgggtg
     4801 ctgcaacagt aatgatggca agtggtgagc gattgcctgc gcaagtcacc tccctcatcg
     4861 aagattgcgg ttataccagt gtttgggacg aattgaagtt tcaggccaag gctatgtaca
     4921 acttgcctgc ctttccttta ctctatgaag tctctgcctt atctaagatt cgagcaggtt
     4981 ttagttacgg agaagcgagc tcagtgaaac agctggctaa aaataaacgt ccaactttat
     5041 ttatccacgg tgataaggat gattttgttc ctacaaaaat ggtttatgac aattataagg
     5101 ccacgaaagg tcctaaggaa atcttgattg ttaaaggggc aaaacacgcc aaatcctttg
     5161 aaacaaaccc agaacaatac cagaaaaaaa ttgccgcttt tttgaaaaaa gttgagaaat
     5221 aagtattgac agttaaactc acagttgcta taataattta tgttactgat gagtagcggg
     5281 gatggcggaa ttggcagacg cgcaggacta aggatcctgt gaccgcttta ggtcgtgtgg
     5341 gttcaagtcc cactctccgc ataatgtaag aggtgaatca ttgattcgtc tctttttgtt
     5401 tggttaaatg aaggataaga aggcatagat ttactgaaga aaacttttga taatctgctt
     5461 ttggaaaacg ctttaagctt gtgaaagact agaaatttat ggaaaattgt gctagaatga
     5521 acaatgtaaa cggggagtta tcccgaaaaa taagaggagg ccttacaaat ggcaatcgtt
     5581 tcagcagaaa aatttgtcca agcagctcgt gaaaacggat atgctgttgg tggatttaac
     5641 acaaacaact tagagtggac tcaagcaatc ttgcgtgcag cagaagttaa acaagctcca
     5701 gttcttatcc aaacatcaat gggtgcagca aaatacatgg gtggttataa agtatgtcaa
     5761 tctcttatta ctaaccttgt tgagtcaatg ggtatcactg ttcctgttgc tatccacctt
     5821 gatcatggtc actacgaaga tgctcttgag tgtatcgaag taggttacac ttcaatcatg
     5881 tttgacggtt cacaccttcc agttgaagaa aaccttgcta aaactgcaga agttgttaaa
     5941 attgcacatg ctaaaggcgt ttcagttgaa gctgaagttg gtacaatcgg tggtgaagaa
     6001 gacggtatca tcggtaaagg tgagctcgct ccaatcgaag atgctaaagc aatggttgaa
     6061 actggaattg acttcttggc agctggtatc ggtaacatcc acggtccata cccagaaaac
     6121 tgggaaggtc ttgctcttga ccacttagaa aaattaacag cagctgtacc aggtttccca
     6181 atcgtattgc acggtggttc tggtattcct gacgatcaaa tcaaagaagc aatccgtctt
     6241 ggtgttgcta aagttaacgt taacaccgaa agtcaaatcg ctttctctaa cgcaactcgt
     6301 gaatttgctc gtaactacga agctaacgaa gcagaatatg atggtaaaaa attatttgac
     6361 ccacgtaaat tcttggctcc aggtatgaaa gctgttcaag gtgctgttga agaacgtatc
     6421 gatgttttcg gatcagctaa caaagcataa tttagagtat taaacaccct aaagccctct
     6481 tgagggcttt tttagatata attgacaccc taaaatggat accagtttct gtgaaacaat
     6541 ctttgattgt gaacaaacaa agcataattt agagtattaa aatctggacc ctgctatcta
     6601 tggtaagtct ttttgttatt gttaaagagg ttaagcggaa tgttaatatg ttttagctaa
     6661 aaaatgtagt gaaaaatgag tacgtagact attgtaatag taattccgta aaattgttga
     6721 aaaagaaaat gggaaatacc ttgtcaaatt aagcacccta tgatagaata gataggtatg
     6781 tggtgctagc acatccgtaa acatattcta cgtaggagga aacagatcaa aatggctaaa
     6841 gtatgttatt ttacaggacg taaaaccgtt tctggaaaca accgttcaca cgcgatgaac
     6901 caaacgaaac gtacagttaa accaaacctt caaaaagtta ctatccttgt tgatggtaaa
     6961 cctaaaaaag tttgggcttc tgctcgtgcg cttaaatctg gtaaagtaga acgcatctaa
     7021 tagaaataag ccttagggct ttttttatta gcttatttct atccataagc tagtcagggt
     7081 aataaacgct atcgttaact attctatctc ttttacatta cttctaaaat atgataaaat
     7141 aggatgataa aaactttttg aggtagtaac tatgactgta aaaattaata caaaagatgg
     7201 tctaatcgag ctatccgacg atgtgattgc aactgtcgtg ggaggatcag caacggaaat
     7261 ttttggtgtt gttggaatgg ccagcaaaag tgcaataaaa gacaattttc aatcactact
     7321 tcgcaaagaa aactacgcta agggtgttgt agtaaaatca acagatctgg gtatttctgt
     7381 tgatgtctac actgtgatga gttatggtgt gaaaatcagt gaagtctcta aaaatatcca
     7441 agaacgcgtg aaatttaacc ttgaaagtca gcttggtctc actgctgata tggtcaatgt
     7501 ttacgtgcaa aatattaagg ttgtaggaga aaattagtgt caaatattac aacaagctta
     7561 ttccaagaaa tggtccaagc ggcagcgact cgccttggca aacaagcaga atatgttaat
     7621 tccttaaatg tttttcctgt tccagatggt gatacaggaa caaacatgag catgactatg
     7681 gacaatggtg ccaaggaagt tgctgataaa cctgcgtcaa ctgtgggaga agttggacaa
     7741 atgttatcaa aaggtctttt gatgggagcg cgtggaaatt ctggagttat tacttcacaa
     7801 ctttttcgtg gttttggtca aagcattaag ggaaaagatg agctgacagg taaagatttg
     7861 gcacaagcct ttcaagtggg tgtagaagtt gcctacaaag cagtgatgaa acctgttgaa
     7921 gggacaatct tgacagtatc tcgtggagca gcaaccgctg ccttaaaaaa agcagatctt
     7981 acagacgacg ccgtggaagt catgcaagct gctttagacg gtgccaaagg tgcccttgct
     8041 aagacacctg atttattacc agtccttaaa gaagttggtg tggttgattc aggcggtcaa
     8101 ggtcttgtct ttatctatga aggtttccta tctgctttga atggcgacta tgtgacttca
     8161 gcagacttta aagcgactcc tgctaacatg tctgaaatga ttaatgctga gcatcacaaa
     8221 tccgttgttg gtcatgtggc tactgaagac attacctacg gttattgtac tgaaatcatg
     8281 gttgccctta aacaaggccc aacctatgtg aaagaattca actatgatga gtttcaaggc
     8341 taccttagtg gccttggtga ctcgctgtta gtggtcaatg atgatgagat tgttaaagtt
     8401 cacgtccata ctgaagaccc cggacttgtg atgcaagaag gtcttaaata tggttcgctc
     8461 atcaagatta aagtggacaa tatgcgtaac cagcatgaag cacaggttca aaagactgat
     8521 gtcgaaaaaa acaaggctga agtaaaagaa tttggcttga ttgcagtagt agctggagaa
     8581 ggtttatctg aaattttcaa ggcgcaaggt gttgattacg tgatttctgg tggtcaaacc
     8641 atgaatccat ctacagaaga tattgttaaa gctattgaag cagttaatgc caaacaagtc
     8701 attatcttgc caaacaataa aaatatcttt atggctgccc aatctgctgc agaagtggtg
     8761 gatatcccgg ctgctgttgt tgcaacatgt actgttccgc aaggatttac cagcttgttg
     8821 gcctttgatc cttcaaaatc tttagaggac aatgtagcag atatgtcaac tagtctttct
     8881 gacgtggtca gtggaagcgt tactttggca gtccgtgaca ccaccattga tggtttagaa
     8941 atccatgaaa atgatttctt gggaatggtt gatggtaaaa tcatcgtttc aaacccagac
     9001 atggaagcaa ctctaaaagc tgcctttgaa aagatgattg acgaagatag cgagattgtg
     9061 actatctttg ttggtgaaga aggtgatcaa gacttagcag aagaacttgc tgggtattta
     9121 ggagagactt acgaagatgt ggaagttgag atccatcaag gagatcagcc tgtttaccca
     9181 tatctcatga gtgtagaata atagaataca ataaaaaaag aggagttagg caaaggtctg
     9241 actctttttg tctatattgg tgtcgtaatg agtggtttta gtgatggtaa gcccctaaaa
     9301 aatgagggta atccatcaca aagctaatgg ttacgattta atttgacaaa acctagaaaa
     9361 acattataat tgtattataa caataagtca agaactgaaa acggttcagt tctaagacat
     9421 gacaaggagg agattttatg ttaggaccat ttatctttat tgcttttggg gttattgtaa
     9481 tcctagctat tgttgccagt accctttatg ttgttcggca acaatctgtt gccatcgtgg
     9541 aacgttttgg taggtaccaa aaaacagcga ccagtggtat tcatgtccgc cttccgtttg
     9601 ggattgacaa aattgctgcg cgtgtgcagt tgcgactttt acagtcagaa atcatcgttg
     9661 aaaccaaaac caaggacaat gtgtttgtaa ctttgaatgt tgccactcag taccgtgtta
     9721 acgaacaaaa tgtaacagat gcttactaca aattaatgaa acctgaatct caaatcaagt
     9781 cttatattga agatgccttg cggtcatccg tgccgaagtt gaccttagac gaattgtttg
     9841 agaaaaaaga tgaaattgcc ttggaagtac aacatcaagt ggcagaagaa atgtcaacct
     9901 atggatatat tattgtcaaa accttgatta ccaaggtgga gcctgatgct gaagtcaaac
     9961 agtcaatgaa tgaaatcaat gcggctcaac gcaaacgtgt agctgctcaa gagttggcaa
    10021 acgcagataa aattaaaatt gtgacagcag cagaagcaga ggctgaaaaa gatcgattgc
    10081 acggggtagg ggttgcccaa cagcgtaagg ccattgtgga tggtttggcg gagtctattc
    10141 aagagcttaa agaagcgaat atttccttaa acgaagaaca aatcatgtcc attttgttga
    10201 ccaaccaata cctggatacc ctcaatacct ttgcggcaaa aggaaaccaa accctttttc
    10261 taccaaatac accaagtggg gtagaggata tccgtacaca agttttatct gcccttaaaa
    10321 caaaataacg tgtaaaaact tggctaaaaa gttgctcaat actggattta gcagaaggct
    10381 atcatacctt gtgaagtggc aaacgacgaa atgaatacat tacttttatt ggagaaatga
    10441 aagtaaaaaa agcctttttc atgattaaca acatagtatt gattaaatgt taagttgtat
    10501 tgacttttaa attaaataag tttaaaatca acttaataag caaaaaggag attttcaatg
    10561 aaatccaaaa aagttgttag tgttatatca cttaccttat cccttttttt ggtgacaggt
    10621 tgtgctaaag ttgataacaa caaatcagtt aatcgtaagc ctgctactaa acaaacctat
    10681 aatagctata gtgatgacca attaagatcg cgtgaaaata ccatgtctgt tttatggtac
    10741 cagcgagctg cggaaactca agcgctttat ttccaggggt atcagttagc aacggatcgc
    10801 ttaaaagaac aactcaataa accaacggat aaaccttatt caattgtatt agatattgac
    10861 gaaacagttc ttgataatag cccttatcaa gctaaaaatg ttttggaagg aacaggattt
    10921 acacctgaaa gctgggatta ttgggtacaa aagaaagaag caaaaccggt tgctggtgct
    10981 aaagactttt tgcaatttgc agaccaaaat ggtgttcaaa tttactacat ttcagacaga
    11041 tcaactactc aagtagatgc tacaatggaa aatctccaaa aagaaggtat tccagtacaa
    11101 ggtcgtgatc atcttctatt cttagaaaaa ggcgtaaaat caaaggagag tcgtcgtcaa
    11161 aaggtcaaag aaacaactaa tgtaacgatg ctatttggtg ataatcttct agattttgct
    11221 gatttttcaa aaaaatctca agaagataga acagctttat tatcagattt gcaagaagag
    11281 tttggaagac gctttatcat tttccctaat cctatgtatg gttcatggga aggtgccatt
    11341 tataaaggtg aaaagctgga tgtgcttaag caactagagg aacgccgtaa aagtttaaaa
    11401 agctttaaat aaagtaattg aaaaagaggt gcaaaagaaa atgtaacctc tttttaagta
    11461 ctattatttt ctgaaaatag ggttaatgac tgaaaaaaat gttgattttg tgaaatgatt
    11521 attttattat tttcatattt tatctttatg ctaggaattg tggtataatg gaggagtata
    11581 aaaaatatta aggagtctat tcacatggct aaattgactg ttaaagacgt tgatttgaaa
    11641 ggtaaaaaag tcctcgttcg tgttgacttt aatgtgcctt tgaaagacgg cgttatcact
    11701 aacgacaacc gtatcactgc ggctcttcca acaatcaagt atatcatcga acaaggtggt
    11761 cgtgctatcc tcttctctca ccttggacgt gttaaagaag aagctgacaa agaaggaaaa
    11821 tcacttgcac cggtagctgc tgatttagct gctaaacttg gtcaagatgt tgtattccca
    11881 ggtgttactc gtggttcaaa attagaagaa gcaatcaatg ctttggaaga tggacaagtt
    11941 cttttggttg aaaacactcg ttttgaagat gttgacggta agaaagaatc taagaatgac
    12001 gaagaacttg gtaaatactg ggcttcactt ggagatggaa tcttcgttaa cgatgcattt
    12061 ggtacagcac accgtgctca cgcatcaaac gtaggtattt cagcaaacgt tgaaaaagct
    12121 gtagctggtt tccttcttga aaacgaaatt gcttacatcc aagaagcagt tgaaactcca
    12181 gaacgtccat tcgtagctat tcttggtggc tcaaaagttt ctgataagat tggtgttatc
    12241 gaaaatcttc ttgaaaaagc tgataaagtt cttatcggtg gtggtatgac ttacacattc
    12301 tacaaagctc aaggtatcga aatcggtaac tcacttgtag aagaagacaa attggatgtt
    12361 gctaaagacc tccttgaaaa atcaaatggt aaattgatct tgccagttga ctcgaaagaa
    12421 gcaaacgcat ttgctggtta cactgaagtt cgcgacactg aaggtgaagc agtttcagaa
    12481 ggcttccttg gtcttgacat cggtcctaaa tcaatcgcta aatttgatga agcacttact
    12541 ggtgctaaaa cagttgtttg gaacggacct atgggtgtct ttgaaaaccc tgacttccaa
    12601 gctggtacaa tcggtgtcat ggacgctatc gttaaacaac caggcgttaa atcaatcatc
    12661 ggtggtggtg attcagcagc agctgctatc aaccttggcc gtgctgacaa attctcatgg
    12721 atcagtaccg gcggaggcgc tagcatggaa cttctcgagg gtaaagtatt accaggtttg
    12781 gcagcattga ctgaaaaata atagtcatta taatatatag taaagggcat gctgatgcat
    12841 gtcttttttt agttgatcat gtacagttat tgaactttcc ctaacttcac ttatcattta
    12901 ctagttttta gatatagtgg tatttggctg acactgcaat tttcaaaagt ttatgacgat
    12961 ttcatatcaa ttggtttata aaagatatcc taattattaa taaaacgttt accaaaaggg
    13021 ttttatggat tgatatgtta aaatagatag tgaagggata ggtatgaaaa cgttaagaaa
    13081 attattatct aattacaagt ttgatattaa aaagtttaaa ttgggaatga gaacattgaa
    13141 aacaggctta tcggtctttt tagttttatt ggtttttcat ttatttggtt ggaaagggct
    13201 ccaaattggt gctctaactg ctgtatttag tttaagagaa gactttgata aaagcgtgca
    13261 ctttggcttt tctagaatta ttggtaatag tataggtggc ctactctcct tagtattttt
    13321 tgcattcaat gagatatttc atcaagcttt ttgggttact ttattaattg ttcctatttg
    13381 taccatgtta tgtatcatgg ttaatgttgc atgtaataat aaatcaggta ttattggggc
    13441 agtggctgct cttttgatta ttacactgtc tattccaaca ggacaaacgt ttatttatgt
    13501 gacttcgcgg gtatttgaaa cattttgtgg cgtctttgta gctattttag ttaatactga
    13561 tgttgaactt attaaaaata aatggtttaa caaaaaacat agtgatgtta gataatataa
    13621 catatatact tgacaggtta tttttttcag cctataataa ggaagatgaa aggagtttgt
    13681 catgaaagaa aaagaactta gacgctcaat ggctgttttt cctattggaa cggtgatgac
    13741 attaacagat ctctctgcga gacaaattcg ctattatgaa gatcaaggtt taattaagcc
    13801 tgaacgaacg caagggaatc ggcgtatgtt ttccttaaat gacatggacc gacttttgga
    13861 aattaaagat tttttgtctg agggattaaa tattgcagct attaaacgcg aatatgtcga
    13921 gcgtcaaggt aagttaatgc aaaaacaaaa agctctaaca gatgcagatg tcagacggat
    13981 cttacatgat gaaatgctga cacaaagcgg tttttctact ccctcacagc atattggtaa
    14041 ttttcgtatt taagatatga attgtataaa atttaaagga gacctattta atggcaatca
    14101 cagtagctga cattcgtcat gaagtcaaag aaaaaaatgt aacgtttctt cgcttgatgt
    14161 tcactgatat catgggcgtt atgaaaaatg tggagattcc tgcaacgaaa gaacagttag
    14221 acaaagtatt gtctaacaag gttatgtttg atggttcatc tatcgaaggt tttgtacgga
    14281 tcaatgagtc agatatgtac ctttaccccg atttagacac ttggattgtt tttccctggg
    14341 gagatgaaaa tggagcagtt gcaggtttaa tttgtgatat ttatacagca gaaggaaagc
    14401 cttttgcagg agatcctaga ggaaatttaa aaagagccct gaaacacatg aacgagatcg
    14461 gctacaaatc atttaatctt gggccagaac cagaattttt cctttttaag atggatgata
    14521 aaggtaatcc gacacttgaa gttaacgata atggtggtta ttttgattta gcgccaattg
    14581 acttagcaga caacacgcgc cgtgaaattg tgaatatttt aacgaaaatg ggttttgaag
    14641 tggaagctag tcatcatgaa gtggctgttg gtcaacatga gattgatttt aaatatgcag
    14701 atgttttgaa agcttgtgat aatattcaaa tttttaagct agttgtaaaa acgattgccc
    14761 gtgaacatgg actttatgct acttttatgg ctaaaccaaa atttggaatc gctggatcag
    14821 ggatgcactg taacatgtct ttgtttgata accaaggtaa taatgctttt tatgatgaaa
    14881 ctgataagcg aggaatgcag ctatcagaag atgcttatta tttcttggga ggactaatga
    14941 agcatgctta taactacact gctatcacta accctacagt gaattcttac aaacgattag
    15001 ttccgggtta tgaggcacct gtttatgtcg cttgggctgg aagtaatcgt tcaccgctta
    15061 tccgtgttcc agcatcacgt ggtatgggaa cgcgtttgga gttacgttcg gttgatccga
    15121 cagctaatcc ttatttagcc ttggctgttc tcttggaagc tggattagat ggtatcatta
    15181 acaaaattga agctccagaa cccgttgaag ctaacattta taccatgaca atggaagaac
    15241 gaaatgaagc aggcattatt gatttgccat caacgcttca taatgcctta aaagctcttc
    15301 aaaaagatga tgtggtacaa aaggcactag gttaccatat ctacactaat ttcttagaag
    15361 caaaacgaat tgaatggtct tcctatgcaa cttttgtttc tcaatgggaa attgaccatt
    15421 atattcataa ctattagact tatcaggacc tgctcaagtt gagtgggtct tttggatgag
    15481 ctattgtatt tgagctagca agctattatt agctgatcgg acaccaattg attttccatt
    15541 atagaaaact aaaaaccagt ccatgttcta tgaggactgg tttttagttt gataattatc
    15601 tgaactagaa ctgatatgtt aaatatatag acagatagta ttaagaaatg agtcttattt
    15661 gattttagtg tttatcaggt gttaagacca tcggaatgat aattggttca cgctcagtct
    15721 tttcatacaa gaatggacga agagcattga cgatagcacc gttaactgat tggatgctag
    15781 catccttatt ttttaaagca atacggatag cgttaaagag cacacgttgg ctttcgcgga
    15841 tcaagtcacc tgactcacgc atataaatga aaccacggct cagaatatct ggtccagcta
    15901 aaatcatttg tgtgttaaaa tcaacagttg caacagctaa gacaacacca tcttctgaca
    15961 aatcacggcg gtcccgtaaa acggctgctc caatatcccc gatgccatta ccatccacgt
    16021 agatgtcttg ggcattaaag tgaccagcaa tacgcgcact gtcactggtt aaagctagaa
    16081 cgtctccatt ttccataata aagatatttt cttttggaat accaatatcc atcgccagtc
    16141 ctgcatgaac tttttgcatg cgatactcac catgtactgg catgaaatat tttggtttaa
    16201 tcaaactaag catgagcttt tgttcttgct gtcctccatg accagaagta tgaatattat
    16261 tgacttttcc atgaataaca tcaacaccag cttcttggat ggtattgatt aatttattga
    16321 cacttgtggt attaccaggg attggacttg atgagaaaat cacagtatca ccaggctgta
    16381 aagttacttg acgatgagtg ccattagcga tacgagcaag tgctgccata gactcacctt
    16441 ggctacctgt acacataatt aaaacttcac tagcatgaag atttttaagt tcgcttggct
    16501 caatgaaggt accttttgga actttaatat agccaagttc aataccgtta acaattgctt
    16561 tttccataga acgaccaaaa acggcaattt tacgtcccgt tttaacagca gcttctgcag
    16621 cctgttgcaa acggtagatg tttgaagcga aggaagcaaa aataatacga ccatgaatac
    16681 cttcgataat ttttaaaatg gattggccaa caactttttc agagttagta aaggttggga
    16741 tttcagcatt agttgagtct gataataagc aaaggacacc ttcttcacca agcgctgcca
    16801 tacgttgtaa atctgcagga tctcctactg gcgtgaagtc aaatttaaaa tcaccagtac
    16861 agataatctt accttgaggg gtgtggataa caataccgac cggttctgga atggaatgag
    16921 tagtcttgaa gaaagtgacg ctcatgtttt taaaagttaa ctcggtgttg tgattgattt
    16981 cgtaaacagt cgattcacgc caaagaccat gttcttccaa tttaccacga ataagagcaa
    17041 gtgctaaagg tcctgcgtag atagggatat tagcctgttt gagaagaaat ggaataccac
    17101 caatgtggtc ttcgtgacca tgtgtaataa caagagcttt gacccggtct aagttatcga
    17161 caatgtaaga atagtctgga ataacgtaat caattcccaa aagatcatct tctgggaatt
    17221 tgataccggc atcaacgata atgatctcgt cttgatactc aataccataa gtattcttcc
    17281 caatctctcc cagaccacca atggcaaaca ccccaacttc attaggtttt aaactgatat
    17341 ttgtcatctt agaactccgt taattcaaaa acaccggtct ctttttcgta atcgaggtgt
    17401 ttgtcagaaa gtagctcgat aaattccacg ttataatagg tgttatcttc aacgagacga
    17461 cgagccttga tacggccatc gagttcatca gtagcatcaa tattaagata gagtgcttta
    17521 gtactttcac gacgtgggct ttgatccttt gtttcttgat agaaaacttt ataaatcatt
    17581 tgttttttat tcctttcgtt atgaatcaat tatccaaaca ataataaata ggtcaaaagg
    17641 taggtgttcc attttgacgg ttttatatgt tgtcattatt gtgtagtaga ttaattcctg
    17701 attctgtgca attattataa ttataccata aacttagctt ttagtaaaaa atttaggtac
    17761 atttatggta tagtctaaat caaattaaga gtcagccttt ttgtttatga ttcttaattt
    17821 gtgttataat tgatactaga acttgcagta gaaaggcata aaatgaagac acttgcattt
    17881 gatacctcaa ataaaacctt gtcccttgct atacttgatg atgagacact tctagcagat
    17941 atgaccctta acattcagaa aaatcatagt gttagcctta tgcctgctat tgattttttg
    18001 atgacttgta ctgatcttaa acctcaagat ttagaaagaa tagtggttgc aaaaggccct
    18061 ggatcttaca caggtttacg agtggcagtt gctactgcaa aaacgttagc gtacagttta
    18121 aatattgcat tggtcgggat ttcgagtcta tatgctttgg ctgcgtctac ttgtaaacag
    18181 tatccaaata ctttggtggt gccattgatt gatgctagaa ggcaaaatgc gtatgtaggt
    18241 tattatcggc aaggaaaatc agtgatgcca caagcccatg cttcactaga agttattata
    18301 gaacaattag tagaagaagg acagctgatt tttgttgggg agactgctcc ttttgctgag
    18361 caaattcaaa agaaactacc tcaggcgata ctacttccaa cccttccttc tgcttacgaa
    18421 tgtggtcttt tggggcaaag tttggcacca gaaaatgtag acgcctttgt ccctcaatat
    18481 ctcaagagag tggaagctga agaaaactgg ctcaaagata atgagataaa agatgatagt
    18541 cactatgtta agcgaatcta atatgaaaac agttgaagaa caagcaaaaa atatttatca
    18601 gcttttggaa atggtttatg gcacgtctcc ttggacttta gaacaagtat taatcgatat
    18661 acggcgggat caaacagatt atttcctact atatgatcat gataaattgc taggtttttt
    18721 agctattcaa gatttagctg gtgaagttga aatgactcaa attgctatac tacctagtca
    18781 tcaaggactt gggctagcgt ctcaattgat gacgcattta gatagcattg aaagtgacat
    18841 ctttttagag gttagagaat ctaatcatag agcacagggt ttatatcaga agtttggttt
    18901 taaatttatt ggcaaaagac cagactacta tagaaatcct atagaaacag ctttattgat
    18961 gaaacgggaa ggaaaacatg acagataggt atattttagc agttgagagt tcttgtgatg
    19021 agaccagtgt agcgatttta aaaaacgaaa gtaccctctt aagtaatgtc attgcaagtc
    19081 aggttgagag ccacaaacgc tttggtggtg tggtgccaga agtagctagt agacaccatg
    19141 tcgaagtgat tacgacttgc tttgaggatg ctttgcaaga agctggcatc agtgcttcag
    19201 atttatcagc agttgcggta acttatggcc ctggacttgt tggagccttg ttagttggat
    19261 tagcagctgc gaaggctttt gcttgggcaa atcatttacc tttgattccg gttaatcata
    19321 tggcaggtca cttaatggca gcgcgtgaac aaaagccttt agtttatcct ttaatagcac
    19381 tgttggtttc aggaggacac acagaattgg tttatgtccc agagccaggg gattatcata
    19441 ttattggcga aacgcgtgac gacgctgttg gtgaggctta tgataaagtt gggcgtgtga
    19501 tgggcttaac ctatccggca ggacgtgaaa ttgaccagtt ggctcataaa ggtcaagata
    19561 cttatcattt ccctcgtgct atgataacag aagaccactt agaattttct ttttcaggac
    19621 tcaagtccgc ttttatcaat cttcatcata atgctaagca aaaaggcgat gaactgattc
    19681 tagaagattt gtgtgcatct tttcaagcag ctgttctaga tattttattg gtcaaaacaa
    19741 aaaaagctct gagcagatac cctgcaaaga tgcttgtagt ggctggtggt gtagcggcaa
    19801 atcaaggatt acgagataga ttagcacaag aaattacaca tatagaagtt gtgattccta
    19861 aactaagact ctgtggagat aacgcgggta tgattgcttt agcagcagct attgagtatg
    19921 acaaacagca ttttgctaat atgagcctaa acgcgaagcc tagtttagct tttgaccagt
    19981 ttccagacag ttttgtaata aactagtcac acttgctagt tagtaagatt tataatggat
    20041 aagaatctcc ctttgaaaaa acaacccggt atcttggcat accgggttgt catgatgata
    20101 agtaattggc ttctatggtt actaataatt cagataatta cctgcaaaat aattgtctgc
    20161 ctaaggtgaa gtaagcttac cagctagctt tagtgacgcc aggaagctgt cctttgtgag
    20221 ctaagtcacg gaaattgata cggctaacac caaacttacg catgtaagca tgaggacggc
    20281 cgtcaatttt gtcgcggttc ttcaagcggt ttggatttga atcacgaggc aatttgcgca
    20341 gtgattcata atcgcccttc gcttttaagt cacgacgaag gtcagcgtac tgttcaatca
    20401 gttggagctg cttttggtat ttagcaattt ttgacttttt tgccattgct ttctccttct
    20461 taatatttaa taacctcaga gtcgttatca gcgctctgaa tccacttaac tggtatttaa
    20521 ctggttaagt ggatatataa tcattataca ataaataaaa gcaaaagcaa ataaaaaaaa
    20581 ttaactagtt atctttttta gccataatat caaaaaactc cacatctaag tgtgggagtc
    20641 aggtattaat aactgtttaa aggtgtttaa tgagtgtcgc tttagcaact ttgagattga
    20701 acttttaagt caaataaatc agcaggaacg tagtgtttgg ttgagaccaa gatgtcttta
    20761 ccattgtaga gagtttcttg gattaaaata aaagcactat tttctgatag agtatactta
    20821 gttgctgtgt aattgccagt cttggtatag ccgatttggt tgcaggaatg agaagcttta
    20881 ccagattcat agattttctc ttctaagaaa gtaagaaggg gctcttcttg attgagattt
    20941 atagcatatt tagaaataac ctcaataggg ataaaagata aactataagc aatagcttta
    21001 ttttggctat gataccagcg atcaacaata atcacaacag gagtttcttg ttttagggat
    21061 gctgtaatgg caacagtggg cacttcaatc cgatattcca attcaacctt tgtgatgtca
    21121 gatgataggc ttgcatatat ggggtgttga agatattcga aaccttggtg atatttagtt
    21181 tcaggagtct tgagtataaa atttcccttt cctctgatat tttttatgag atgatcctct
    21241 tggaggaggg ctagggattt acgcagtgtc atccgactga cattgagctg tctagcaagt
    21301 tcaggttctg atggcagttg catgccagga ctatatgtac catcttgaat aagttgaaaa
    21361 atagtattat atacttgcac atgtttaagt tttttgagtt ttttggttaa gtcgttagta
    21421 gacatatcac ttacctcatt aataatcttt agtggagttt aacttgtcta aaaactattt
    21481 tagcactaac agtatttctt gattagaatt gtacccatct atagtgttag tatctcacac
    21541 tcaggtactt tttgtcaaaa aagagatgaa aaacacctta aaaaagcgtt tacaaaatag
    21601 agtgtgtgtg atactataca agtgtatcaa aaattagaca agtaaaatac aggaggtttt
    21661 taacatgcaa aattattcag gtgaagtcgg attgcaatat cacctacaga ttcgtccagg
    21721 tgatgtaggt cgttatgtta tcatgccagg tgatccaaaa cgttgtgcaa aaattgcaga
    21781 acattttgat aatgcagttc ttgtagcaga cagccgtgaa tatgttacgt atacaggtac
    21841 attaaacggt gaaaaagtta gtgttacttc aactggtatt ggtggtccat cagcgtctat
    21901 tgcgatggaa gaattgaaac tttgtggcgc tgataccttt atccgtgttg gaacatgtgg
    21961 tggtattgac cttgatgtta aaggcggaga catcgttatt gcaactggag ctatccgtat
    22021 ggaaggtacc agtaaagaat atgctccgat tgaatttcct gctgtagctg acttggaagt
    22081 gacaaatgct ctagttaatg cagctaaaaa gcttggttat acaagtcacg caggagtagt
    22141 tcaatgtaaa gatgcatttt acgggcaaca tgagccagaa cgtatgccag ttagttatga
    22201 attattaaat aaatgggaag catggaaacg tctgggaaca aaagcgtctg aaatggaatc
    22261 tgcagctctt tttgtagcag caagtcatct aggagttcgt tgtggatcag atttccttgt
    22321 tgttggtaat caagaacgca acgctttggg tatggataac ccaatggctc atgatacaga
    22381 agcagctatt caagttgctg ttgaagcact ccgcacactt attgaaaatg ataaatcaca
    22441 ataagcgagg ttttggaagt catcatgcaa tttatttata gtattattgg tattttattg
    22501 gtattaggaa ttgtgtatgc aatttctttc aatcgtaaga gtgtttctct aagtttaatt
    22561 ggaaaagctc ttatcgttca attcattatt gcgctaatct tagtacgtat cccactaggc
    22621 caacaaattg ttagtgttgt ttcaactgga gttactagcg taatcaactg tggtcaagct
    22681 ggtttaaatt ttgtgtttgg gtcattagca gatagtggcg caaaaactgg ttttattttc
    22741 gctattcaaa cgcttggtaa tattgttttc ttatctgccc tagttagtct actttattat
    22801 gtaggaatcc ttggatttgt agtaaaatgg ataggtaagg gcgttggtaa aattatgaaa
    22861 tcctcagagg ttgagagttt tgttgctgta gctaatatgt ttcttggtca aacagacagt
    22921 ccaatcttgg ttagcaaata cctaggtcgt atgactgata gtgagataat ggttgtgttg
    22981 gtatcaggta tgggaagtat gtcagtttct attcttggtg gctatattgc attaggcatt
    23041 ccaatggaat atctcttgat tgcttcaaca atggttccta ttggcagtat tctcattgct
    23101 aaaatcttat tgcctcaaac agaacctgtt caaaaaattg atgacattaa gatggataat
    23161 aaaggtaata atgctaatgt gattgatgca atcgctgagg gtgcaagcac aggtgcacaa
    23221 atggctttct caattggtgc tagtttgatt gcctttgttg gtttagtttc tttgattaat
    23281 atgatgttaa gtggattggg aatccgctta gaacaaatct tttcatatgt ttttgctcca
    23341 tttggttttc ttatgggatt tgaccacaaa aacattcttc tagaaggaaa ccttcttgga
    23401 agtaagttga ttttaaatga gtttgtttcg ttccaacaat tgggtcacct aatcaaatct
    23461 ttagattatc gtacagcatt ggtagcaact atttcactct gtggttttgc taatttatca
    23521 agtttaggta tttgtgtttc aggtattgct gttctttgcc cggagaaacg tagcacccta
    23581 gctcgacttg ttttccgtgc aatgattggc ggtattgctg taagtatgct tagcgccttt
    23641 atcgtcggta ttgtaactct attctaaaag ttgacaaaag aaagaaggat agtaacgtgg
    23701 aagtaaaaga tattttaaaa acggtagacc atactttgct agcaacaaca gcaacatggc
    23761 cagaaatcca aacaatttta gatgatgcca tggcttatga aacagcttca gcatgtattc
    23821 cagcttctta cgtcaaaaaa gcagcagaat acgtttcagg taaattagct atttgtactg
    23881 ttattgggtt cccaaatggc tatagtacaa ctgcagcgaa ggtttttgaa tgtcaagatg
    23941 ctattaaaaa tggtgctgat gaaattgaca tggtcattaa tttgacagac gttaaaaatg
    24001 gggattttga tactgttgaa gaagaaattc gtcaaatcaa agccgcatgt caagaccata
    24061 tcttaaaagt tatcgttgag acatgtcaat taactaaaga agaacttatc gaactttgtg
    24121 gagttgtcac acgttcaggt gcagacttta ttaaaacctc tactggtttt tcgacagcag
    24181 gtgctacatt tgaagatgtt gaagtgatgg caaaatatgt cggcgaaggt gttaaaatta
    24241 aggcagcagg tggaatctca tcattggaag atgctaaaac atttattgct ttaggagctt
    24301 cacgcttggg tactagccgt atcatcaaga ttgttaagaa cgaagctaca aaaaccgata
    24361 gctattaact taatcacacc gatttagctt gagacttaaa caaaaaactc atataatagg
    24421 agttaaaaag cctactatct tagtgataat aggctttttt agctatgaag acttccctgc
    24481 gatccatcct gaacaaagag ctgaggtaat attaaaccct ccggtgtgag cattaatatc
    24541 taagacctct ccagcgaaat acaggccagg aactttcttg ctttccaagg ttttagggtt
    24601 gatttctttt aaatctacgc ctcctttggt cacaaatgat ttagccaaag acatttttcc
    24661 tgtaatgggt atctggaggt gtttgagttt atcaagcaat tccttttctt gttttggaga
    24721 gagttgtttg accttttcgg ggtaatcttc tgataaaaaa tcagctactc gttcaggcag
    24781 taggccttta agagtatttt tgatgttttt atcacgttga tcactcagat aagcggttaa
    24841 gtcatctgtt gataagtgtg gcaaaaagtc cagctctgca atttctccac ctttcacaaa
    24901 agaggacaga cgaagagctg caggtcctga aaggccaaag tgggtgaaga gtaagtcgtg
    24961 tgtgatgacg tgtttgtcat aactaagagt aacgtcgtct agggaaatac cttgcaagac
    25021 tttgtgaggg aaatcagtta acagagggct ctcagcagct tctaaatcag tcacggtcag
    25081 tttaaaatgc cgtgcaatat catatccaaa acctgttgaa cccgttgaag ggtaggactt
    25141 gcctcctgtg gtcacaatca atttttggca ggtgaaagtc tggtctgcag atttgaggta
    25201 gaagaggtca tcttgttttt taacggaaac cacttcagtg ctggttagca cctgaccccc
    25261 aagagccttg atttttttct ccagagcatc aatgattgtc ctagatttat ctgttgtggg
    25321 gaacatccgt ccatggtctt cttctttgag tttgacgccg ttttcctcga aaaaggcaat
    25381 gatgtcatgg ttgtcaaact gggaaaaaac actatataaa aagcggccat tcccaggaat
    25441 gcctgccata aggtcatcaa gattaccact attagtgaca ttacagcgtc caccaccggt
    25501 tcccgctaat tttttaccta agcggcgatt tttttcaatt aagagagttt tatagccata
    25561 gtagctgctg gagatggcgg ccatcatacc agcagggcca cctccaataa taatcgtatc
    25621 gtattgagtc atagccttat tttagcataa aagcggggga tttaatagtc aggtatggca
    25681 taccgttttt tacgcattta aacaatgcct ccatgacatc aaaaagctag aaaaatagtc
    25741 cagatgatta aaattatctt tttatgaaaa cggttgcttt tttattta
//
LOCUS       DAUGSW010000022        25292 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUGSW010000022 DAUGSW010000000
VERSION     DAUGSW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25292
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.022"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(528..914)
                     /gene="rplQ"
                     /locus_tag="VIB18_001081"
     CDS             complement(528..914)
                     /gene="rplQ"
                     /locus_tag="VIB18_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEQ8766095.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(929..1867)
                     /locus_tag="VIB18_001082"
     CDS             complement(929..1867)
                     /locus_tag="VIB18_001082"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEQ8766096.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1913..2296)
                     /gene="rpsK"
                     /locus_tag="VIB18_001083"
     CDS             complement(1913..2296)
                     /gene="rpsK"
                     /locus_tag="VIB18_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEQ8766097.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2314..2679)
                     /gene="rpsM"
                     /locus_tag="VIB18_001084"
     CDS             complement(2314..2679)
                     /gene="rpsM"
                     /locus_tag="VIB18_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEQ8766098.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2697..2813)
                     /gene="rpmJ"
                     /locus_tag="VIB18_001085"
     CDS             complement(2697..2813)
                     /gene="rpmJ"
                     /locus_tag="VIB18_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEQ8766099.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2839..3057)
                     /gene="infA"
                     /locus_tag="VIB18_001086"
     CDS             complement(2839..3057)
                     /gene="infA"
                     /locus_tag="VIB18_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEQ8766100.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3175..3813)
                     /locus_tag="VIB18_001087"
     CDS             complement(3175..3813)
                     /locus_tag="VIB18_001087"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEQ8766101.1"
                     /translation="MNLLIIGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3963..5267)
                     /gene="secY"
                     /locus_tag="VIB18_001088"
     CDS             complement(3963..5267)
                     /gene="secY"
                     /locus_tag="VIB18_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEQ8766102.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5284..5724)
                     /gene="rplO"
                     /locus_tag="VIB18_001089"
     CDS             complement(5284..5724)
                     /gene="rplO"
                     /locus_tag="VIB18_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEQ8766103.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5938..6120)
                     /gene="rpmD"
                     /locus_tag="VIB18_001090"
     CDS             complement(5938..6120)
                     /gene="rpmD"
                     /locus_tag="VIB18_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEQ8766104.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6135..6629)
                     /gene="rpsE"
                     /locus_tag="VIB18_001091"
     CDS             complement(6135..6629)
                     /gene="rpsE"
                     /locus_tag="VIB18_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEQ8766105.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6648..7004)
                     /gene="rplR"
                     /locus_tag="VIB18_001092"
     CDS             complement(6648..7004)
                     /gene="rplR"
                     /locus_tag="VIB18_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEQ8766106.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7109..7645)
                     /gene="rplF"
                     /locus_tag="VIB18_001093"
     CDS             complement(7109..7645)
                     /gene="rplF"
                     /locus_tag="VIB18_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEQ8766107.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7848..8246)
                     /gene="rpsH"
                     /locus_tag="VIB18_001094"
     CDS             complement(7848..8246)
                     /gene="rpsH"
                     /locus_tag="VIB18_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEQ8766108.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8397..8582)
                     /locus_tag="VIB18_001095"
     CDS             complement(8397..8582)
                     /locus_tag="VIB18_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEQ8766109.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8598..9140)
                     /gene="rplE"
                     /locus_tag="VIB18_001096"
     CDS             complement(8598..9140)
                     /gene="rplE"
                     /locus_tag="VIB18_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEQ8766110.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9164..9469)
                     /gene="rplX"
                     /locus_tag="VIB18_001097"
     CDS             complement(9164..9469)
                     /gene="rplX"
                     /locus_tag="VIB18_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEQ8766111.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9548..9916)
                     /gene="rplN"
                     /locus_tag="VIB18_001098"
     CDS             complement(9548..9916)
                     /gene="rplN"
                     /locus_tag="VIB18_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEQ8766112.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9941..10201)
                     /gene="rpsQ"
                     /locus_tag="VIB18_001099"
     CDS             complement(9941..10201)
                     /gene="rpsQ"
                     /locus_tag="VIB18_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEQ8766113.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10227..10433)
                     /locus_tag="VIB18_001100"
     CDS             complement(10227..10433)
                     /locus_tag="VIB18_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEQ8766114.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10443..10856)
                     /gene="rplP"
                     /locus_tag="VIB18_001101"
     CDS             complement(10443..10856)
                     /gene="rplP"
                     /locus_tag="VIB18_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEQ8766115.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10860..11513)
                     /gene="rpsC"
                     /locus_tag="VIB18_001102"
     CDS             complement(10860..11513)
                     /gene="rpsC"
                     /locus_tag="VIB18_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEQ8766116.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11526..11870)
                     /gene="rplV"
                     /locus_tag="VIB18_001103"
     CDS             complement(11526..11870)
                     /gene="rplV"
                     /locus_tag="VIB18_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEQ8766117.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11886..12164)
                     /gene="rpsS"
                     /locus_tag="VIB18_001104"
     CDS             complement(11886..12164)
                     /gene="rpsS"
                     /locus_tag="VIB18_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEQ8766118.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12303..13136)
                     /gene="rplB"
                     /locus_tag="VIB18_001105"
     CDS             complement(12303..13136)
                     /gene="rplB"
                     /locus_tag="VIB18_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEQ8766119.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13154..13450)
                     /locus_tag="VIB18_001106"
     CDS             complement(13154..13450)
                     /locus_tag="VIB18_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEQ8766120.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13450..14073)
                     /gene="rplD"
                     /locus_tag="VIB18_001107"
     CDS             complement(13450..14073)
                     /gene="rplD"
                     /locus_tag="VIB18_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEQ8766121.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAVFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14097..14723)
                     /gene="rplC"
                     /locus_tag="VIB18_001108"
     CDS             complement(14097..14723)
                     /gene="rplC"
                     /locus_tag="VIB18_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEQ8766122.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILVKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14971..15279)
                     /gene="rpsJ"
                     /locus_tag="VIB18_001109"
     CDS             complement(14971..15279)
                     /gene="rpsJ"
                     /locus_tag="VIB18_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEQ8766123.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15478..16767)
                     /locus_tag="VIB18_001110"
     CDS             complement(15478..16767)
                     /locus_tag="VIB18_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEQ8766124.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKLPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDT
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEIIFH"
     gene            complement(17156..18172)
                     /gene="adhP"
                     /locus_tag="VIB18_001111"
     CDS             complement(17156..18172)
                     /gene="adhP"
                     /locus_tag="VIB18_001111"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEQ8766125.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLQVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18424..21066)
                     /gene="adhE"
                     /locus_tag="VIB18_001112"
                     /gene_synonym="adhC"
     CDS             complement(18424..21066)
                     /gene="adhE"
                     /locus_tag="VIB18_001112"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEQ8766126.1"
                     /translation="MTEGHNTVETTSVSVTINALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21375..23150)
                     /locus_tag="VIB18_001113"
     CDS             complement(21375..23150)
                     /locus_tag="VIB18_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEQ8766127.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMIGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGSLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23147..23548)
                     /locus_tag="VIB18_001114"
     CDS             complement(23147..23548)
                     /locus_tag="VIB18_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766128.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23571..24008)
                     /locus_tag="VIB18_001115"
     CDS             complement(23571..24008)
                     /locus_tag="VIB18_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEQ8766129.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            complement(24146..25144)
                     /gene="ruvB"
                     /locus_tag="VIB18_001116"
     CDS             complement(24146..25144)
                     /gene="ruvB"
                     /locus_tag="VIB18_001116"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEQ8766130.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25175..25273)
                     /locus_tag="VIB18_001117"
                     /pseudo
     CDS             complement(25175..25273)
                     /locus_tag="VIB18_001117"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
BASE COUNT         7477 a         5332 c         4456 g         8027 t
ORIGIN      
        1 aattttgttg gaaacgactt aaagtgacag attttaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt aaaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttacgat gcaagttttt ttcggacatt taaacgaggg
      181 gattacaccg tttatttgcc catgagaggt ctttaaacac ctgcataagg ttttcttatt
      241 ctgatgacct tattgtctct gaaaaaactt tataaacgca tcagaagagg cttctgtgtt
      301 attgttttgc tcagcttaaa agcggggggg tgttcacctc ataatacaac aaaacgcctg
      361 cttataaaaa gtttctatag cttagatacc tttcataaac aagcgttaca tattaacaat
      421 atgatgagtg ttcccgctag gaaaaatcct agcggtagac cagagctaga ctaagaataa
      481 tctctcgatt actccatcat cataacactc aacaaaattg ataaaaatta aactaattca
      541 ataattgcca ttggagcagc atctccacgg cgtggttctg ttttaagaat acgagtgtat
      601 ccaccgttac gttctgcata acgaggtgca atttctgaga aaagtttttg aagagctgtc
      661 gttgatgtgt atttatcggt agcttcatca taattttctg atgcgatttc gttacgaacg
      721 tatgcagctg cttggcgacg agcatgaaga tcaccacgtt taccaagagt aatcattttt
      781 tcaactgttt tacggatttc ttttgcacgt gcttctgtcg ttacaattga ttcgttgatc
      841 aaaagatctg tcgtcaaatc acgaagcatt gctttacgtt gtgagctagt gcgtcctagt
      901 ttacggtaag ccattttgtc ctcctatatt atttatcgtt ttttagtccg agacctaagt
      961 cagcaagttt aaccttaact tcttcaaggc tcttacgtcc aagattacgg actttcatca
     1021 tttcaggctc agatttttct gttaagtcga agacagtgtt aatgcctgca cgttttaaac
     1081 agttatatga gcgtacggat aaatcaagct cctcgatggt gcggtcaagt accttttcat
     1141 cgttcacttt ttcagtttct ttcattactt cggtagcttt tgcaacctct gttaaatcag
     1201 taaacaggtt taaatgttcg atcaaaactc gagcagatag acctaaagca tcttcaggaa
     1261 taattgttcc gtttgtcatg atttcaatcg ttaatttatc aaagccatca ttgctaccta
     1321 cacgggcagg ttcaacttga taattaactt ttttaactgg cgtatagatt gaatctactg
     1381 ccaatgtacc cacaggtgca tcatcttttt tatttccttc tgctggcaca taaccacgtt
     1441 tcttagcaac agtcattgtt gcacgtagag aatgtccttc agcgattgta aaaagataat
     1501 gatccgggtt aacaagttcg atatcactgt cagtaagaat atcaccagct gttacctctg
     1561 ctggtccttc tacttcaagt tcgataatct tttcgtcttc gacgtatgat ttcacagcaa
     1621 gtcccttaac attaaggata atttgcatga catcttcacg tacacctggg attgtatcaa
     1681 attcgtgtag tactccatca attttaattg atgttactgc tgcacctgga agtgaagaca
     1741 agagtacacg acgaagagaa ttacctagag ttgttccgta gccacgttca agtggttcga
     1801 tgacaaatct accgtaatct ttattttcat caatttttgt tattattggt ttttcaaact
     1861 caatcatttt ttcacccctc gaaacgaaac ttgtgtacta tttgttatat gattatacac
     1921 gacgacgttt tggaggacga gcaccattat gtggcacagg ggtcacatca cgaattgcag
     1981 ttacttcaag acctgcagct gctagagcac gaatagctga ttcacgacct gaaccaggac
     2041 cttttacagt cacttcaaca gtttttagtc cgtgttcttg tgcagatttt gcagcagctt
     2101 ctgcagccat ttgagcagca aatggagtag atttacgaga acctttgaaa ccaagagcac
     2161 cagctgatga ccatgcaaga gcattaccat gcacatctgt aatcataaca atagtgttat
     2221 taaatgtagc gtgaatgtgt gcaacaccag attcgatgtt ctttttcaca cgacgtttac
     2281 gtgttggttt agccaattgt tttacctcct attttatttt ttcttacctg caatcgcaac
     2341 agctttccct ttacgagtgc gagcattgtt tttagtattt tgtccacgga caggaagtcc
     2401 acgacgatga cggattccac ggtatgaacc gatttccatc aaacgtttaa tgttcatgtt
     2461 tacttcacgt cgaaggtcac cttcaacttt gattgcatcc acttcacgac ggatagcatc
     2521 ttcttgatct gatgtcaaat ctttaacacg gatatcttca gaaatacctg cagctgctaa
     2581 gattttttta gatgttgcaa gaccaattcc gtaaacataa gtaagtgaaa ttactacgcg
     2641 tttatcattt ggaatatcaa ctccagcaat acgagccatt ttttctcctt tctattttat
     2701 ccttgacgtt gtttgtgttt tggatttgtc ggacaaatta ccataacacg accattacgg
     2761 cgaataactt tacagtattc gcaaattggt ttaaccgatg gtcttacctt catgttttaa
     2821 tccctccaat tatttcgatt atttaaagcg gtatgtgatg cgtccacgtg tcaagtcata
     2881 aggactcatt tctactgtaa cacggtcacc tactaaaata cgaatgtaat ttttgcggat
     2941 ttttcctgat acagttgcta gaatttgatg tccattttcc aattcaacag taaacattgc
     3001 atttggcatc gtttctacta ctttgccttc aatttcaatc acgtcttctt ttgccacgca
     3061 aaagtacccc ctaaatttcg atttgatgtc ctctgagcac agaggtaaca attataagtc
     3121 agactaaact agtatatcat tactaatcta cttatgcaag tagattagta taatttattt
     3181 gagttctagc aacgcttttt caacatctgc aaaaacgtct gttatttctt gattaccttc
     3241 aatatctgta acaagaccaa gcttacgata gtgttcaaga ataggttctc cttgagccat
     3301 attgacgtcc aaacgacgtt taacagtttc aggcttatca tcttcacgtt gatagtaatc
     3361 ttcttcttta taatctactg gtgggttgaa cactttatgg aacgtttcac cagttttacg
     3421 attgataata cgaccactca aacgctctac aagacatgat ggatccactt taatattaat
     3481 aacaccatct aagcggagtc ctagttcttc aagtgttgca tctaaggcgt gtgcttgttc
     3541 aatagtacgt ggatacccat caagcaaaaa acctttttct gcgatatcat cctcagctaa
     3601 gcgctctttt acaatcccgt ttgtgacttc atcaggaacc aattcacctt tatcaatata
     3661 acttttagct aaacgtccca tttcggtttg attagccatt gcggcgcgga acatatcccc
     3721 tgttgagatg tgagcaacac caaattcttc aacaatctta gctgcttggg tccctttacc
     3781 agctcccggc aaacctatga ttaaaagatt catcttttcc tcctctttta aaataaatac
     3841 atagtaggaa attattttcc ttggtttttg ttttcaaatg gcaacaagaa atcgtttgat
     3901 gataaccaag tcttattgtc atttaaaaac aaaatagaag gttgacaatg tcaacctgta
     3961 ttctattctg ctgtattcat aaatccgaca tattttctct ttagaagata tccctcaagc
     4021 tgtttcatac cttcgatacc agttgaaatc aaaatgagca aactagttcc acctaaagca
     4081 atactagaag aaaggttgag agcttgttgt gctgctattg gcgctaaaga gataaatgct
     4141 aagaagatag ctcctacggt tgctagtttt tttagcaatg cggacataaa ttgttctgtc
     4201 tcacgtccag ggcgaacact tggtatatat gaggaattct tctgaagatt ttctgctgtc
     4261 ttctcaggat taacttgtac aaaggtatag aagaatgaga acaatataat caacaaggcg
     4321 taaactatca ttccgactgg agtttgataa ttaaaaattt cttgcaaacg gtttaaccac
     4381 ggtaaatctc taccattttg aacaaaagga ataatcgtac ttgggatagt tgtaatcgag
     4441 ctagcaaaga taacgggaat aacgccggct ggatttactt ttaatggaag atatgaactt
     4501 gtaggtgcac cttgcattag ctttgtgtat tggattggaa ttttatattc cgcttgttgg
     4561 acatatgttg taaagaaaac aatagcaaga acagctatga ttaaaatccc aacaatgaga
     4621 taagacgagt gtaaatcact tgccttaaca tttacaaaat agtcttcacg aattgttgca
     4681 attgcacttg gaatagacga aataataccc gcaaagataa tcattgatac gccattacca
     4741 aatcctttat cggtgatttg ttctccaagc caggtaacaa taacgctacc tgttgtcagt
     4801 aatgccccga tcagtaaata tgttttgatg tctggtgtct taacaagtgc aacgttcgac
     4861 aaagtattaa accctgcagt gataccaatg gattgggcaa aagccaaaac aagtgaaata
     4921 tagcgcgtcg cttgatttaa tttacgacgt ccaacctcac cttgtttgcc ccactcaaca
     4981 aacttaggta aaatatccat ctgcaataac tgaacaacga tagaagcagt aatatatggg
     5041 ctaaccccca ttgaaaatac tgagaaattt ctcatcgcat taccactaac taagtttaac
     5101 atatttaaga aagggagttc acttaattgc tctaagctct tggcatttac accaggtacg
     5161 gtaatatgtg tcccaattcg gaatacaaga atgataaata tagtaaagaa aattttattc
     5221 cgtacagtct ttatctttaa cgcgtctttt agtattttta agaacataat gagtatcccc
     5281 tcattagatg acttcgattg aaccaccttt agcaataata gctgcttcag cagattttga
     5341 gaacttagct gcttttacag tcaatttttt agtcaattca ccgttaccaa gcactttaac
     5401 gcctgatttt tcagctcgga caataccagc atcttttaaa atagccggag tcacttctgt
     5461 accatcatca aaaacattca gttgatcaag attcacaagt gcatattctt tagtattgat
     5521 atttgtaaag ccacgttttg gaatacgacg gaacaatggt gtttgtccac cttcaaaacc
     5581 taaacgtaca ccgccaccgc tacgagcttt ttgacctttt tgaccgcgac cagatgtttt
     5641 accattacct gatgatgtcc cacgaccaac acggttacgt actttacgtg agccttcagc
     5701 agcttttaat tcatgaagtt tcattttttc tccttttttt gtaaaatgct agcgcctcta
     5761 tgagggaaaa ggactcccta tagaaactcg cctatacatt aatgatactt aagttatcca
     5821 aaataactta atacagatac gcactaaccg actactgttt gttgccaaaa agcaaactac
     5881 aagagtcggt tttgtgctcg tttttaatta tgaaatcaga gatttcacag ttataactta
     5941 tttaacatct tcaacggtaa ccaagtgaga aatagctgtc accataccac ggatagcagc
     6001 attatcttct ttgactactg aagagtttaa tttaccaagt ccaagagcaa caacagtttt
     6061 acgttgttct ggcttacgtc cgataggaga cttagtcaaa gtaattttaa tttgagccat
     6121 gatgatcccc tttcttatgc taagtcagaa actgagatgc cacgaagtgc ggcaacttct
     6181 tctgcacgtt taagttgttt caatccttca acagttgcac gaacaatgtt gattggagtg
     6241 tttgaaccaa gagattttga agtaatatca gcaacacctg ctaattcgat gacggcacga
     6301 actgcaccac cagcagcaac tccagaacct tctacagctg gtttcaataa tactttagct
     6361 ccaccgaagt tagtgtaaac ttcgtgaggg attgttgtac caaccattgg tacttcgatc
     6421 atgtttttct tagcagcttc aactgcttta cggatagctt ctggaacttc ttgagcttta
     6481 ccagtaccaa atccaacacg accatttcca tcaccaacaa ctacaagagc tgcaaagcga
     6541 agacgacgtc cacctttaac aacttttgta acgcggttaa tcgcaacaac gcgttcttca
     6601 agttcaactg cattatcttt aaatgccatt attttgtgtc ctccctatta gaatttcaat
     6661 ccgttttcac gagctgcatc agccaaggct ttaacacgtc cgtgatagag atatccaccg
     6721 cggtcaaaca ccacttcaga aataccttta gccactgcac gttcagcaac aagtttgccg
     6781 actacaacgg cttgttctgt ttttgttcct ttagaaacgt ctttatcaag agttgatgca
     6841 cttgcgagcg ttacacccgc tacgtcatca ataacttgag cgtagatgcc tgtattagaa
     6901 cggaatacgt tcaaacgtgg gcgatcagca gttccagaga gtttaccgcg gacgcgacgg
     6961 tggcgttttt ggcggatttt gtttttatct ggtttcgaaa tcacaatttt cacctcttaa
     7021 ttttaatcaa tttgtctcat tgacaagttg tcgattgaac ttatcgagca tgttaaggtg
     7081 caatacttcc catacccgac taagaacatt atttacctgt tttaccttct ttaaggcgta
     7141 cgtattcacc aacgtaacgg atccctttgc ctttgtaagg ctctggtgaa cgcaagctac
     7201 ggatgtaagc agctgtttga ccaacaactt ctttgttgat tccttcaact gagattgaag
     7261 ttgggttagc aacagtgaaa gtaattcctt ctggagcttc aacttcgtct tggtgagatt
     7321 tacctactga aaggacaagt ttagtacctt gaagttgagc acggtaaccg acacccttca
     7381 tttcaagatc ttttttgaaa ccttcagaaa cacctacaac catgttattc aagttagcac
     7441 gggttgtccc atggattgtt ttcatttctt ttgagtcgtt aggacgtaca actgtgattt
     7501 cagtcccttc aactttgatt tcaatatttt tgttgaactc acgagtgagt tcgcctttag
     7561 ggcctttaac agtaataaca ttgttgttat ttgttaattc aacacctgca ggcatagtaa
     7621 ttactttatt accaatacgt gacatgttta ttttctcctg ttaaattgtc aagccgcata
     7681 gcgactagtt ttcacggggg tttgatagaa tgatatactt caatttatat ttcaaaattg
     7741 aacacgagct gtggtctgtg tgaaaaagat aaatcctcct tgagtgtaaa cacgctacgt
     7801 cagatttcct attttcactt tgtccacgac gctcttagta tcttaaatta ccaaacgtaa
     7861 gcgatcactt ctccaccaac attcttttgg cgagcttctt tgtcagttaa aagaccttct
     7921 gatgttgaaa tgattgcaat tccaagtccg ttaagaactt taggcatgtc atcacgtttt
     7981 gcgtaaacgc gaagacctgg ttttgaaata cgttttaagt tagtgataac acgctcacca
     8041 ttttttccgt attttaagaa cacacgaatg atgccttgtt tatcatcttc gataacttca
     8101 acatttttta caaaaccttc acgtttaaga atctcagcaa tccctttttt aatgtttgaa
     8161 gcaggtactt ctaacacttc gtgttttact tgattagcat tacggatacg tgttaaaaag
     8221 tctgcaattg ggtcagtcat aaccattttt tatattctcc tcttactagc agtttgatgc
     8281 tatcacttac tagttaatgt tgtccttaaa ggactttggt atcagcttat gctcacaccg
     8341 ttttaattaa gcacaagact taatctgaag aacaaattaa gttttgtgtc atatttttac
     8401 caagaagctt tgacaacacc tggaatttga cctttgtaag ccaattcacg gaagcaaaca
     8461 cgacaaagtt taaacttgcg gtaaactgaa tgtggacgtc cacatttttc acagcgagta
     8521 taagcttgtg tagagtgttt tgcaggacgt ttgttcttag caatcataga ttttttagcc
     8581 aatttattta ccccctatta ttttgcaaaa ggcattccaa ggcccttaag caattcacgt
     8641 gattcttcgt cagtatttgc agtagtgacg attacaatat caagaccacg tactttatca
     8701 acatcatcaa agctgatttc tgggaagata agttgttctt tcacaccgag agtgtagttt
     8761 ccgcgtccat caaacgactt tgttggaacg ccatggaagt cacgtacacg aggaagtgaa
     8821 acgctaacca atttgtctag gaattcgtac atacgttcgc cacggagggt aacttttgca
     8881 ccgatcgcta caccttcacg aagacggaag ccagcgattg atttcttagc tttagtaata
     8941 agtggttttt gacctgagat aagtgctaat tcagctgcag ctttctctag gttttttgcg
     9001 ttggatacag catcaccaac acccatattg agaacaattt tctcaacttt tggcacagcc
     9061 ataactgatg tgtaattgaa tttctctgtc aacgcaggaa ttacttcgtt agtatatttt
     9121 tcttttaaac gatttgccat tatgcttctc ctttccttcg tgattaatca agcacttcgc
     9181 ctgatttttt gctgtaacgt acttttttac cgtcaacaac tttataacca acacgtccag
     9241 ctacaccatt tttatctaat acttgaacat tagagacatg gataggtgct tctttttcga
     9301 cgatagctcc ttgaggattt tcagtgttag gtttttggtg ttttttaatc attccaacac
     9361 cttcaacaat aactttgtta acttttggaa gtgctttaag aactacagct tcagtgcctt
     9421 tgtccttgcc agcaattacg cgaactttgt cgcctttttt tacaaacatt ctggtttctc
     9481 ctattatttc ttacgccccg atgggcaccc taggaaaacc taggggacta cgtttgttaa
     9541 cctgagatta aagtacttct ggtgcaagtg atacgatctt catgtagcca ccctcacgca
     9601 attcgcgtgc aactgggcca aagatacgag ttccgcgagg agttttatca tcacggatga
     9661 ttacagcagc attgtcgtca aatttgatgt atgaaccgtc tggacggcgt gcaccagttt
     9721 ttgtacgaac gataacagct ttaaccacat cacctttttt aactgctcca ccaggagtag
     9781 cttgttttac agaagcaacg attacgtcac cgatgttagc gaatttacgt cctgaaccac
     9841 caagtacttt gatagtcaag atctcacgag caccgctatt atcagcaact ttcaagcgag
     9901 tttcttgttg aatcatttca attttctcct tttagtttga ttagataata acagcttttt
     9961 ctactacttc cacaagacgg aaacgttttg tagctgaaag tgggcgagtt tccatgatac
    10021 gaacgatatc gccttcttta gcaacgttgt tttcgtcatg tgctttatat tttttagaat
    10081 agttgatacg tttaccatag actgggtggt tacgtttagt ttcaactaca actgtgattg
    10141 ttttgtccat cttgtcagac actacgcgtc cgtaaagagt tttacgttga ttacgttcca
    10201 tttagaattt ctcctttccc aatctattat ttcatttctg attgcacagt tttaacacgt
    10261 gcaatttgtt tcttaacttc gtcaaggcga gcagtctttt caagttgacc tgctgcagct
    10321 tggaaacgaa gatcaaacaa ttcttttttg agttcgtttt ctttcttagc aagttcttct
    10381 tgagacaatc cacgaagctc tttaacaaaa tctttaattt cttgaagttt catgtcttct
    10441 ccttattctg cttcacgttt tacgaatttg cacttaactg gtaatttgtg gctagcaaga
    10501 cgtaatgctt cgcgagcaat ttcttcagaa acaccagcaa tttcaaacat cactttacca
    10561 cgtttaactg gtgctaccca accttcaggt gcccctttac cagaacccat acgtacaccg
    10621 atagcttttg cagtgtatga tttgtgtggg aagattttaa tccaaacttt accaccacgt
    10681 ttcatgtaac gagtcatcgc aatacgggca gcttcgattt gacggtttgt aatccagtgg
    10741 ctagttgtgg cttgaagtcc gtattcaccg aatgaaactt ctttaccacc tttagcctca
    10801 ccgcgcattt ttccacggaa ttcgcgacgg tgtttaacac gtttaggtac taacatttgt
    10861 tatttgcctc ctttagtgtt tttacgagct ggaagaactt ctccacggta aatccaaact
    10921 ttaacgccaa gtttaccata agttgtgtca gcttcttccc aagcatagtc gatatcagcg
    10981 cgaagcgtgt gaagtggaac agttccttct gaataacctt cagcacgagc gatatcagca
    11041 ccgttcaaac gaccagaaac ttgagtttta atccctttag ctcctgcacg cattgtacgt
    11101 tggattgctt gtttttgagc acgacggaaa gcaacacgtt gctcaagttg acgagcaatg
    11161 ttttcaccaa caaggtgagc atctaaatca ggttgtttga tttcgatgat gttgatgtgt
    11221 acttgttttc cagttaattt gttaagttga ccacgaagag cgtcaacgtt tgcgccacct
    11281 ttaccgataa ccatacctgg tttagcagtg tgaagtgaaa caataacttt gtttactgca
    11341 cgttcaattt caatagttga aactgatgcg tcagctaatt ctttattaat gaatttacgg
    11401 attgcaagat cttcatgaag gtaatccgcg tattcttttt cagcatacca tttcgcatcc
    11461 cagtcacgga tgattccgac acgcatacca attggatgta ctttttgacc cacgatttta
    11521 cctccttatt tttctgatac aactacagtt acgtgagttg tacgtttgtt gattggtgaa
    11581 gctgaacctt tcgcacgtgg acggaaacgt ttcattgttg gtccttcgtt agcgaatgtt
    11641 tcagatacta ccaagtttgc tttttccaaa ccaaagttgt tttctgcgtt agcaattgct
    11701 gagttaagag ttttctcaat aacacgagct gctttgtttg gagtgaattt taagattgcg
    11761 attgcgtcag caactttctt accacggata agatcaagta ctaaacgtgt tttacgaggt
    11821 gaaacacgca ctgtacgagc cattgcttta gctgaagtaa tttctgccat tgtgtcctcc
    11881 tcctattaac gacgtgtttt cttgtcgtca gctgcgtgac ctttgtaagt acgcgttggt
    11941 gcaaattcac caagtttgtg acctaccatg tcttcttgga tgtaaacagg tacatgttta
    12001 cgtccgtcat aaactgcgat tgtatatccg atgaaacttg ggaaaatcgt tgaacgacgt
    12061 gaccaagttt tgattacttt tttcttttcg tcgtttgctt gagcttcaac ttttttcatc
    12121 aaatgctcat cgacgaaagg tcctttttta agactacgtc ccattttgta gttttctcct
    12181 ttaaaaaatg taccacagcg gcttgagttc aaaagcaaga ctccaaactc taccgagttg
    12241 gcggaataaa tagcaaagct attgtaacgc tatttcagca agttttaagc aacttactaa
    12301 gattattttt cgttacgacg acgaacgata agtttgtctg atttagcttt cttgttacga
    12361 gttttaagac caagcgctgg tttaccccat ggagttgatg gcgctttacg tccaactggt
    12421 gctttacctt caccaccacc gtgtgggtga tcgttagggt tcattacaga accacgaact
    12481 gttgggcgga tacctttcca acggctacgt cctgctttac caatgttaac aagtgattgt
    12541 tgttcgttac caacagtacc gatagttgca cggcatgtac caagaatcat acgaacttcg
    12601 cctgattgaa gacgaacaag aacgtattta ccttcttgac caagtacttg agcagaagct
    12661 ccagctgcac gaacaagttc tccaccttta ccaggtttca actcaatatt gtgaacaact
    12721 gtaccaacag gaatgtttgc taatggaagt gcgttaccaa ctttgatatc tgcatctgga
    12781 ccagaaacaa tacgttgacc tacttcaaga cctttaggtg caatgatgta agctttcaca
    12841 ccgtcagtgt aatgtacaag tgcgatgttt gcagtacggt ttggatcata ttcgattgtt
    12901 ttaacaactg cttcaacgcc atctttgtta cgtttgaagt cgatcaaacg gtaatgacgt
    12961 ttgtgtccac caccttggtg acgaactgtg atgcgaccat tgttgttacg accagctttg
    13021 ctcttaagag aaacaagcaa tgatttctca ggcgtgcttg ttgtgatttc cgcgaaatcc
    13081 aaagaagtca tgttacgacg gccatttgtc gttggtttat aaactttaat acccacgtta
    13141 tttcctcctt agattattca gcttcagctg cgaacaactc gattgcttta gaatcagctg
    13201 taagagtgat gatagctttt ttagtttttg aagtgaaacc tgtgtaacga ccaacgcgtt
    13261 ttgcttttgg tttaacgtta acagtgttta cacttgcaac tttaactccg tcaaaagcag
    13321 cttcaacagc ttgtttgatc aaaagtttgt gtgcacgagt atcaacttcg aaagtgtatt
    13381 tgcctgcttc aagagcaatc attgacttct cagtgataac tggttttttg attacgtcgt
    13441 acaaattcat tatgcaagaa cctcctcaat tgtagagatt gcttctttag taacaagaag
    13501 tttgtctgcg ttcacgatat caagaacact tgcagttgct gcagttgcaa cagttacgtt
    13561 tggaaggtta cgtgcagaaa gtgctgcaaa ttcatttcct tcttcaacaa gaacaagtac
    13621 ttttgtatca atgctaagag ctgaaagcac ttttgcaaat tcagcagttt ttggtgctgc
    13681 aaatgaaagg ccttctacag ctacaaattt atcttcagca acttttgctg agtaaactga
    13741 tttcaacgca aggcgacgaa ctttttgtgg aagtttgtat ccgtatgaac ggggagttgg
    13801 tccaaagaca acaccaccac cacgccattg tggtgagcgg atagaacctt gacgagcgcg
    13861 tccagttcct ttttgacgcc atggtttacg tccaccacct gatactgctg aacggttttt
    13921 aaccgcatga gtaccttggc gaaggctagc gcgttggcta attacaacat caaaaacaac
    13981 tgattcgttt ggttcgatac cgaagacagc gtcgtttaat tcaactgagc taacttcttt
    14041 accagtttgg tcaaatagtt ttacgtttgc cattttaact gttttctcct ttcttattat
    14101 ttagcagctt taactgctga cttgatagtg ataagagatt tcttagcacc tggtacgtta
    14161 cctttaacaa ggataacgtt cttttctggg ataacttgta caatttcaag gttttgaact
    14221 gttacacggt taccgcccat acgtcctgcc aagcgtttgt ttttgaaaac gcggttaggc
    14281 gcaacaggtc ccatagaacc tgggcgacga tggtaacgag aaccgtgagc cataggacca
    14341 cgtgattgac catggcgttt gataacacct tggaaacctt taccttttga tgtccctgtg
    14401 acgtcaacaa catcaccagc ttcaaattgt tctacagata attctgcacc aacttctaag
    14461 ccttcaatgt ttttgaattc acgaatgaag cgcttaggag ctgtgtttgc ttttgcaaca
    14521 tggcctttgg caggtttgtt actcaagact tcacgtttgt catcaaaacc aacctgaact
    14581 gcttcataac cgtctgtttc aacagtttta acttgaagca caacgtttgg agttgcttca
    14641 atgacagtaa cagggatgaa ttcgcctgat tcagtgaaga tttgagtcat tcccactttt
    14701 ttccctaaga ttccttttgt catgagaaaa tatttccttt tcttaataat atttcaaaaa
    14761 gttttttatg agcgtttttt gtgctcaaaa aagtttttta cgagcgtttt ttgtgctcat
    14821 agcaagatac aaagagcgtc aaactcaaaa taaaaataga aaatctaaca caaaaacttc
    14881 tgtttcgagg aagatttatc tttttcatgt agagtttagc tcgtgttcaa gttccatcaa
    14941 acactaactg tacttgcaaa atctcaccga ttaaagtttg atttctacgt tgacaccact
    15001 tggaagatca agtttcatca aagcatcaac agttttttgt gttggattga tgatgtctac
    15061 caaacgtttg tgtgtacgca tttcaaattg ttcgcgagaa tctttgtatt tgtgagtcgc
    15121 acgaataatt gtgtaaagac tgcgttcagt tggaagtgga actggtccag caactgtagc
    15181 acctgtacgt gttgcagttt caacgatttt ttctgccgct gtatcaagtg tacggtgttc
    15241 gtacgctttc aaacggatac ggattttttt gtttgccatc ttttctcctc tcgtctattt
    15301 acgataatag gctagctcct caagaaaacc gacacctgtt gcgtggcaat gcaaccgagc
    15361 gtgtcgcaac ctcttgtatc attgctaaag ctgtattttt acagcaccac aatataataa
    15421 cagaatcatt tagtcattgc aagcttttta ggcatttttt tcaaaaaaac taccttccta
    15481 atgaaagata atttcttggt actttttaaa ttgtttagag agaataaacc accgactggt
    15541 attatctaac actgtcgcca tccagacccc tatgagtcca tattgccaaa ccacaccaat
    15601 cacataacca aggccaatgc gaatcaccca cattcctatg gttgttgcat agaaaggaag
    15661 ctttgctttt cccaaaccct gccagacggc tgtataaact aaagtgcctg ccgttgcggg
    15721 agctcctagt aaagaaaaaa gtaaaacaac catggcggac ctttgagtat cagtattctg
    15781 agtaaatagc ggcaagagac taggacctag cagataggtc aaggctccca taaccagcat
    15841 catgagggtg gataaaataa aagcttctct aataatatac cttatctcag tcaccttacc
    15901 gccccccagt tgcctggcca ctagaataat tgttgccgtt gccatggcta agccaggcat
    15961 gtaattaaac tgagtcaagg tttctccaat agcattacct gccaaggccg ttgtcccaaa
    16021 gcgaacaaca atgccaataa ttaggacatc tcctgctctc atcatcaaac gttcaccagc
    16081 agcaggtagt gataaatcaa aaataatttt gtccaaaggt ctcatcaatc gtttcgcaac
    16141 ctgtttaata ggaataaact gacaaagtaa aaacactccc actaaacgag ataaaaccgt
    16201 cgcccaagca acaccaagaa gaccaaatcc ccatacatag atagacaagg cagaaaaaat
    16261 ggcattgagt acgtttatta ataagctcac ttgcatagga agcttaggat acccttgagc
    16321 tcgaacaata gctcctaagc tagttaaaag tcctagacta acaatcatac cgccgacaat
    16381 ggatagatat tgccctccaa ccaatgttac agaagcttca gctcctagcc attctaacac
    16441 ctgatgatgt ccaacaactg ataacaaccc taagccgacg gaaaggagga gtgttacttg
    16501 caagacacct gccatatagt ttaattgttt gttctgatta ttttctccaa tacttcgagc
    16561 aatcagacta gatacagcag ctcccagcgc gataaagagg gactgataaa tactgataat
    16621 gttgttagct atggagacac cagagactgc tacaagtcca atttgagcca ccaggtaatt
    16681 atcaaccatt cccattaaca tctgtaaaat attttctatc atagaaggca gagctaaaga
    16741 gaaaattttt cttctattat atatcattta tgtcccctaa taaaaaattc ttgatcaaac
    16801 gatttttttc aaacacagtc actggactca ttcagttatt ttggtccatt aatgaattca
    16861 taaagtctat cttaatagca gagtcccaag gtacacgaca cttagtgcta cagtaacaat
    16921 tgaccacatg ccaatcctta acatttacct aacgtttata actaagaaga tgaagaacaa
    16981 aaggactcca aacgaatttt ttctattata taatatattc ttcatttagc aactttcaat
    17041 gtatcaaaat agcactctcg agtcaaaaat gttttctgat actcgagagt gctattttat
    17101 ttggaatcaa gtttaagcaa cttaggctta tctcatattt aatacatttg tatgtttagc
    17161 tgatgaaatc taagaccttg cgcccttgga ttaaaccacg ttccatttca tcaaagactt
    17221 ctggagcagt gtcaactgga actttttcga caaccggagc aaccagacct tctgcaccaa
    17281 aggcaaaggc ttcttccaag tctttacgtg tccctacaag tgatccgacc actttgatac
    17341 catctaaaac agtttttacg atagacagtt ccatgtattc tgatggaaga cctacggcta
    17401 caactgttcc accggcacgg acactatcaa ttgcttggtt aaaagcaact ttagaaacag
    17461 ccgttaccac aacaccatgt gctccaccgg ttttttcttg aatatagcct ggaacatctt
    17521 caatttcttt gccgttaact aaaatatctg cgccaacttc tttagctaac tcaagtttat
    17581 cattattaat gtccactgcg acaacatgtg cattaaagac ttttttagcg tattgaacag
    17641 ccagatttcc aaggccacca gccccaaaga taacaatcca ttggcctgga gcagcacccg
    17701 cctctttaat agctttataa gttgttacac cagcacaagt aatggaagaa gcttgagccg
    17761 ggtctaaacc ttctggaact ttaactgcat aatcagctgt tactactgca tattcactca
    17821 ttcctccatc aacactgtat ccagcatttt taacactacg acaaagtgtc tcacgtcctg
    17881 tagtacagta ttcacaatgg ccacaaccct caaagaacca agcaatagag acacgatcac
    17941 caacttgtaa tgaggttaca ccttcaccaa tttcttcgac aataccaatg ccttcatggc
    18001 ctagaatacg cccaggaact tgtccaaaat cgccatgtgc aacgtgtaaa tcagtatgac
    18061 aaacgccaca gtattctact ttaacaagcg cttcaccatg accaatattt ggaagatcat
    18121 gctcaacaac ttcgacacct gtactagctt gattaacaac tacggctttc atatcagtcc
    18181 tccatctaat aatgactttt ttgtaatcgg ttacaaataa attgtacatc ttttcacaat
    18241 gaaagtcaat agaaacctga aaagtttctg aaacttaact ggttaatctt atagctgttt
    18301 gcctatctgc aaaatactta actacatttt ctgacactgg atataaatga tatatttaga
    18361 aaataaaatg atttcttatg actttaatca taagaaatca tttcctggta tcaacattaa
    18421 aaatcactta cgtcgtcctg gacgttcagc ataaccatag taagcatctt caataatttc
    18481 ttgcatgtga tcaaccattg gaagacgtgg gttagcaggt gaacattggt cttcataagc
    18541 aaggtaagcc aattcacgag aatgttcttt ccattcattt tcgtcgatac cttgagcttt
    18601 gaagttcatt tgaataccaa ctcggcaacc cagatcataa acagctttcg cataagattc
    18661 cactgcttct tctggtgtag aagctggaag ccctaacaat ttcgcaatgt cttggtattt
    18721 ttcatccgca cggtagtaat tatacttagg ccatgtcgcc gttttagctg gacgagttcc
    18781 attatagcgg ataacatacg gcaaaagaat tgcatttgta cgtccgtgta cggtatggaa
    18841 ttgtgcgcca attttatgcg ccattgagtg agaaatacct aagaatgcat tggcgaaagc
    18901 catacctgcc atagttgacg cattgtgcat cttttcacgt gcttcaaaat cggctgtttt
    18961 aactgatttt tcaagattat caaaaacaat tttaatggct tgaagagcta aaccatccgt
    19021 aaagtcattg gccatttgtg acacgtaagc ttcggttgcg tgtgtcaaaa cgtccatacc
    19081 agtatcagca gcaataaagc ctggaacagt caacaccaaa gctgggtcaa caatggctac
    19141 agttggtgtt aatgagtaat cagcgattgg atatttacga ttatttgctt tgtcagagat
    19201 aacggcaaat ggtgtcacct ctgaacctgt tccagaagtt gttgggatag caacaaattt
    19261 tgttttctta ccaagttctg ggaatttgaa cgcacgtttg cggatatcca tgaatttttg
    19321 aacgaggtca tggaaatcaa cttctggttg ctcgtagaag agccacataa ctttggctgc
    19381 atccatagga gatcccccgc caagggcaat aatggtgtct ggtttgaagg tacgcattaa
    19441 ttcagtacct ttcataacag ttgtaatgtc tggatctggt tctacttcag caaagatctg
    19501 ataaacaact ttgttgcgac gaagatcaag ttgttcaatg atacgatcca agaaaccaag
    19561 ctcaaccata gcgtgatctg taacaatcat gacacgttca acgtcacgac atttttgcaa
    19621 atattgaatt gaatcacgtt cgaagtatgt ttttgaagga actttaaacc attgcatatt
    19681 atttctacgt cttcctactt ttttgatgtt caagagattt atagcactaa cattatcacc
    19741 aactgcgtta cgtccatacg aaccacaacc aagagtcaat gatggcaaga aagcattgta
    19801 aacatccccg ataccaccaa atgtagaagg tgaattccag atgacgcgga tagcacggat
    19861 tctagttcca aattcttttg ccaactctgc atctgctgta tgaatggcag ctgagtgacc
    19921 gagtccatta aattcaacca tttgacgagc tttttcaaca ccgtcttcac gtgattcaga
    19981 tttcaaaaca gcaatgactg gagataattt ttcacgtgtt aaaggctcat tttctgaaac
    20041 ttctttacat tctgcagcaa gaatattggt tccttctgga acagtaaatc cagcttgttc
    20101 tgcaatccaa gtagctggtt ttcctacaat atttggattt aattttgcac cagcacagtt
    20161 tttgctattt gctttggcac caaaacagaa ttcttcaaga agggcttttt cttttttatt
    20221 tacaaaataa gtatggtaag atttgaattc tgctacaaaa tcgtcataga tttctttatc
    20281 gatgataaca gcttgttcag aggcacagac cataccatta tcaaatgatt tagacatcac
    20341 aatatcatga gcggcttgac ggatattagc tgatttttca acataagctg gaacgttacc
    20401 agcacctacc ccaagggcag gtttcccaca tgagtatgcc gctttaacca tcgcatttcc
    20461 acctgtcgca aggatagtgg caatgccgtc atgattcatc aaagcatttg ttgcttcaag
    20521 tgatggtgtt tcaacccact gcacacaatt ttcaggagca ccagcggcaa tagcagcatc
    20581 acgaacaata cgagcggcat gtgctgatga ttcttgtgct gatgggtgaa aggcaaaaat
    20641 aattggatta cgtgttttta acgagatcaa agatttaaag atagctgttg aagttgggtt
    20701 agttgtgggt gtaataccac agataacacc caccggctca gcaattaatg tcaaacctgt
    20761 cacatcatct tcttcaataa ttcctactgt tttttgatgg cgcatgttat taaccacatg
    20821 ctcacaagca aatagatttt ttgttgcttt atcttcaaag acaccgcgac ctgtttcttc
    20881 ataagcatgt ttagcaagtt caccgtgagc atccaaggca gcaacagaag ctttggctac
    20941 gatataatca acttgttctt ggtcaagctt acgcatctct tcaagagcag ctaaaccttt
    21001 ttgaacaaga gcattaattg tcacagaaac agaggttgtt tcaacagtat tatgtccttc
    21061 agtcatttga gactccttta tcttgttaaa agtttcacaa ttttgtttac aaaattatta
    21121 tagcactttt tgaaattttg taaatcattt cacaataaat ttgtgaagtt tttttcaaat
    21181 tatttctgaa atcctatggt atcaatatta ttcattaact ctttttcaga aatatatcta
    21241 aaaaaagccg ttttatttct gaaatcgctt tcttttaaaa acctcaaagt actactattt
    21301 taccatcatc atttgttcac aagaaaaagc cagagcacaa tggatctgac ttatctctta
    21361 gacatttctt aactttattt agctggtttt ttagctgact tctcaacagc agtctggatt
    21421 gtggagacat atagttctgc tccttgacta tcttcactat aatgaacacc gtcactgcca
    21481 taccaaatat ctggatgttc aacagcaact ttataccagt ctgcaatagt gacatacttg
    21541 tattttttgg acaatttaag accatagtct ctagcttctg caacctgact ggcatttttg
    21601 gcattatatg gagaaaccaa aactaaacga tgtccttttg gcaatgcctc aataaaagac
    21661 tgaactgctt gagaatagtt gtcaagcgag ttaacaccta ctgctaagac aacagtctta
    21721 gatagactct tagacttaat ttggttatta aataaatcga aagcttcttt aaaattccga
    21781 ctgaccgctg catccagttg cgcttgtggc ataatttttg agaatgctgc actagagcgt
    21841 aatgctacag aatcaccaat aatacctacg tcactcaaag cattagcgtc tcctgcagct
    21901 agtgtatgtg tccgctccat attactttga gcctgttgta gggaactgac caacaattgt
    21961 ttctcaaact taccaacttt aggcgctatc atacaagttc ctaaagttaa taatgctaag
    22021 gcgagagacc ctcctacaat ccacttatag taaggagaac agtcaatttc taaaccaagc
    22081 aggtttggtt ttctcccttg gaccaaaggt tccacaatat agtaagacac agtggcaaac
    22141 aagattgaaa agaaaactgt tagaataact gccaaaatat gagacattaa ttggctaaaa
    22201 ataatgtaaa atggccaatg gaagaggtaa atcccatagc taatatcagc tatataagtg
    22261 atagctttag gctcttgtac atctggtgtt tgctcatgaa gaacacgcgc tgcataaatc
    22321 ataattgatg cgaataagct agccaaagca aagccaaata gataggtcgt gatatggtta
    22381 aaatccaatg tgaccgttag cacaagcaaa agtgtaaatg ctccaatcat agcagcaagg
    22441 acatactggc gcggccataa acgtacattt ttttgaaatc gaacagtagt ctcgttaata
    22501 cctgttattg tggcaaacat cgcccctaaa aagaagggaa aactgtgaga aagactcgaa
    22561 aaataaatca gggaaaaatt tgaggtcata aaagatctta taaacatgct caagaaacta
    22621 atagcaaata ttcccaaaga aatcaaaaac agtagtcctc tcagttgttt ctgagtctcc
    22681 ttgcgtctag ctaataacca aacaaataca ccccacaaca agtaaaaatg aacttcaata
    22741 gctaagctcc acgtatgaac aaagagatgt ggaataaatt ggctttcata actacttccc
    22801 gtcaatattt cataaatatt agtggtaaat cctaaaacag ctgtaatctg acttcctata
    22861 ttagcaatga aatccttctt aattaaaaac gtaaaaggaa tggtcaataa aatcattaac
    22921 accaaaggag gaacaattcg ataaaagcgt ctttttaaaa aaccgataat atcgatagac
    22981 tctttttttg tgtattcatc aatcaagagg gctgtgatta gatatcctga aaaggtgaag
    23041 aaaatatcaa caccaataaa acctcctgga aatacatttt taaaaaagtg gtagagcaaa
    23101 accagtaaaa gtcctgttac cctaacaaac gaaaaccatt ttattctcat ttttgaaata
    23161 tcccctgttt aaaaatccct ttatagactt tattattctt tgcttttaac acacctttgc
    23221 catttgcttg tcctttatga aactccccgt tatataacca gcccgtctta gcagtaaaag
    23281 ttccttttcc ttcaaatagg ccattcttaa aagtaccctc atagatatca ccgttggggt
    23341 agacaagctt cccttctcca ttcattttat ggttaatcac gtaaccagta tagtgcatac
    23401 gccctttatc ataggtcaaa cttgtcttat tcgaaattct tacgctaaaa acagaaattg
    23461 cacaaaccaa tatgacaatc accgagacaa tttccaactt cgcccgtgta atactccatt
    23521 tttttactat atcttgcata tctatcattt cttttactca acttctaata tcaatactct
    23581 ttactcatta aacgagaaag ccaatcctgg catccttttc taactaattg gtaggtttct
    23641 tcaaaatcgt tagtgtacca aggatcagga acaccccctt ctctaaacag gtagatttta
    23701 gagtcccatt gatgttgcga catctctttg agatttttca cattatcgct atccatacca
    23761 ataatatagt caaaggtgtt aaaatcagtt atagttatct gcttggagca tttagttata
    23821 tcataattaa tttggtaagt ttttaatata gactgtgtac ctgagtgaat agggtttcca
    23881 tgctcccaat cagaagtagc acgactttct atcatcataa catcacttga tactattgac
    23941 ttcattacaa actcagccat ggggcttcga caaatattac ccagacagac aaaacatact
    24001 tttttcatta aatactcctt tgaattatta tatcaaattt ctaactgata tcggagaaat
    24061 caatctaata attttctgtc aacttatcaa aaaatccgaa cacaaaaagc aggttcagat
    24121 taattttctt agatttgaaa aatcattaag tgttttgata gggatagcca agatgacgat
    24181 aagccttttg cgtcgctaca cgacctgttc gtgttcgcat gagaaagcct ttttgaatta
    24241 agtagggttc atacatctct tcaactgtat tacgctcctc ggcaatattc acagataatg
    24301 tccccaaacc aactggccct ccctgataca tctcaatcat cgttcgtaaa attttttgat
    24361 caatgtaatc gagaccttcg cggtcaacat ctaacatagt caaagctcta tcagttattt
    24421 gagccgttat gatgccatca ccaataattt gagcatagtc acgcactcgt tttagtaatc
    24481 gattagcaat gcggggcgtt cctctactgc gacaagctaa tttccgtgca gcttcatggt
    24541 ctatttttat ttcaaaaata gtagctgtac gctccacaat ctctgtcaaa tccttttctt
    24601 gatagtattc catgtgacca gtgataccaa aacgagctct gaggggatta gataacatgc
    24661 ctgcacgtgt agtagcacca atcaatgtaa atggaggcag atccaaatga atactacgac
    24721 tagtatctcc agcgccaatc ataatatcaa tatagaagtc ttccatagca ctatatagta
    24781 cttcctcgac agacattggc atgcggtgaa tttcatcaat aaacaaaata tcccctggtt
    24841 ctaattcatt taaaatagct accaaatctc cagctttctc aacggcagga cctgaagttt
    24901 gctttaaatt aactcccaat tcattggcaa tcacaaatgc cattgttgtt tttcccagtc
    24961 ctggaggtcc aaataataaa acatggtcta aagattcgtc acgtctttta gctgcttcta
    25021 taaaaatagc gaattgttcc ttaactttat cttgtccaat atattcgtgt agatattgag
    25081 ggcgaagagt ccgatccgaa aactcctcat ttcccattac attattgtct aaaattctag
    25141 ccataggact attataacat aaagtaaaag agaattaacc aagattccac caatcaaatt
    25201 catgcattac acgagcaact ttaaatgcaa ctactgcggc taatagtaaa aatggcttaa
    25261 ctttttttaa catcttctat ctcccaaaaa at
//
LOCUS       DAUGSW010000023        23923 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUGSW010000023 DAUGSW010000000
VERSION     DAUGSW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23923
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.023"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            19..546
                     /locus_tag="VIB18_001118"
                     /pseudo
     CDS             19..546
                     /locus_tag="VIB18_001118"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            671..823
                     /locus_tag="VIB18_001119"
                     /pseudo
     CDS             671..823
                     /locus_tag="VIB18_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(870..1400)
                     /locus_tag="VIB18_001120"
     CDS             complement(870..1400)
                     /locus_tag="VIB18_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEQ8766131.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(1393..2727)
                     /locus_tag="VIB18_001121"
     CDS             complement(1393..2727)
                     /locus_tag="VIB18_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HEQ8766132.1"
                     /translation="MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNIL
                     LDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTA
                     LSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYK
                     QIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVE
                     DIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKL
                     LGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKS
                     IDFWHKTGGGLAEETINELIEKGYRIARNGISNYTTFKHSRVIFLDQIPDDTDDIVTT
                     KDVPSWKRMCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE"
     gene            complement(2949..3248)
                     /locus_tag="VIB18_001122"
     CDS             complement(2949..3248)
                     /locus_tag="VIB18_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766133.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(3405..3872)
                     /gene="perR"
                     /locus_tag="VIB18_001123"
     CDS             complement(3405..3872)
                     /gene="perR"
                     /locus_tag="VIB18_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEQ8766134.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(3924..4379)
                     /locus_tag="VIB18_001124"
     CDS             complement(3924..4379)
                     /locus_tag="VIB18_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEQ8766135.1"
                     /translation="MIYSFQNPSENVLKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEAQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNH"
     gene            complement(4566..7208)
                     /gene="polA"
                     /locus_tag="VIB18_001125"
     CDS             complement(4566..7208)
                     /gene="polA"
                     /locus_tag="VIB18_001125"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEQ8766136.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMSQEPVAALSYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPVKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(7339..9066)
                     /locus_tag="VIB18_001126"
     CDS             complement(7339..9066)
                     /locus_tag="VIB18_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEQ8766137.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMAMTSGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAQKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(9082..10278)
                     /locus_tag="VIB18_001127"
     CDS             complement(9082..10278)
                     /locus_tag="VIB18_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8766138.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(10766..11857)
                     /gene="ulaG"
                     /locus_tag="VIB18_001128"
     CDS             complement(10766..11857)
                     /gene="ulaG"
                     /locus_tag="VIB18_001128"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEQ8766139.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(12110..13756)
                     /locus_tag="VIB18_001129"
     CDS             complement(12110..13756)
                     /locus_tag="VIB18_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEQ8766140.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWM
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(14081..14785)
                     /locus_tag="VIB18_001130"
     CDS             complement(14081..14785)
                     /locus_tag="VIB18_001130"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEQ8766141.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVARMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(14787..15650)
                     /locus_tag="VIB18_001131"
     CDS             complement(14787..15650)
                     /locus_tag="VIB18_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEQ8766142.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDSATEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLT"
     gene            complement(15655..16317)
                     /locus_tag="VIB18_001132"
     CDS             complement(15655..16317)
                     /locus_tag="VIB18_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEQ8766143.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     IKEVRGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(16408..16893)
                     /locus_tag="VIB18_001133"
     CDS             complement(16408..16893)
                     /locus_tag="VIB18_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8766144.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVRLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            complement(17016..17294)
                     /locus_tag="VIB18_001134"
     CDS             complement(17016..17294)
                     /locus_tag="VIB18_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8766145.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(17365..18798)
                     /locus_tag="VIB18_001135"
     CDS             complement(17365..18798)
                     /locus_tag="VIB18_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8766146.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGIIQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(19105..21606)
                     /locus_tag="VIB18_001136"
     CDS             complement(19105..21606)
                     /locus_tag="VIB18_001136"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEQ8766147.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFKLDIIPVLEGGNVEEAAFTEDGLHINSGFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEAKLFSDYVKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(21817..22956)
                     /locus_tag="VIB18_001137"
     CDS             complement(21817..22956)
                     /locus_tag="VIB18_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEQ8766148.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLQTPSNPLLKICDISELVQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
     gene            23440..23733
                     /locus_tag="VIB18_001138"
     CDS             23440..23733
                     /locus_tag="VIB18_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766149.1"
                     /translation="MKNKLFLVALATVTVLGPSLATPRHQTVHAANVSPAGTCTHPKE
                     DSTISVCYESTDGTSEEEEKTVKTTTNSDSFLTWLWTTITTWFSSLMNKMGIS"
BASE COUNT         7159 a         5218 c         4413 g         7133 t
ORIGIN      
        1 cgttcttcat gaactcgtcc caatcttgtt aatcaatgtt tccaagcgac tggtaagaat
       61 aaattatggc taggagactt aacctacatt cctacacaag aaggaatact ttatgtgtct
      121 gtctttatag acgtttatag tagaaagatt gttggttggg caatgggccg acgtatgcaa
      181 gacaagttgg taacagaagc tttcaatcaa gcttataata gagaaaagcc taaagaaggg
      241 gtaatcgtcc atacagatca gggttctcaa tataccggag cacgatttca ggacctactt
      301 agatggaaaa aatgtaagtc caggatgagt cgaaaaggta atccatacga taatgcactc
      361 atggaatcct tttataaaac attaaaaaga gagcttgtca atgatgctca tttcgcaact
      421 attaagcaag ctcagcttga gatttttaaa tatagtgaga cttactataa ccctaaacgt
      481 ctgcattcag ctttagggta tctctcacct gttgaatttg aaaaaaatag ttactcatta
      541 gcttaacttt atgtctattt tttcttgaca agtccagggt atgaagtccc cttatacaca
      601 tactttcaaa acagctctca atcctctgtc cgctacaaaa atacgtcacc gctgccctcc
      661 agctgcttca ttcaacgaca aacttgaagc cacaaacaga ctcatcaagg gcattaagta
      721 caatgccttt agatttcaga actttgacaa ctttaaaacc aaaatcctca tcgctttgaa
      781 catccaaaaa gagagaacca atctgattct ctctcgttgt taatgataag tcacccacta
      841 cagttgacaa tgagtctctt acttcctgtt tactcattta atagctcttc tggttcccaa
      901 gattgattaa actcatggtc cttaaaaaga gaagccaatc ctgttatttg tttcagtctt
      961 aaaatttcat ctttatccat tcctaaatgt tttgcaatcc agttatcact tcgcccacac
     1021 tcatgaagat cctttacaat ctgactcatc aaatcaacat catgacttcc tctagctcta
     1081 ttatgtcgaa tggtagaagc cattcgatag tctaatgact tatcaataac agaaacaggt
     1141 aatctcccac tttccctttc ataaatatct gaataatcta gcattatacg atatctatga
     1201 aaaccatcaa caatactata ccgatcctct tccttatcgt aatagcaaac aatcggcata
     1261 gtataaccat cagattttat actatcatac aataatttca tttcaggcgg agcaactgaa
     1321 ttcggattat aatcatttgg agaaatcttt tcaattggaa ttgatttaat ctcatagact
     1381 ggactaataa aattactcac tttctaactc ctttaaactc gtcttatatt tctcttttaa
     1441 aaaggctact attttttgtt gctctcttgt caaaccaaac cccatagttc gacaaatatg
     1501 atcatttttt aaaatacaga aacacattcg tttccagctt ggtacatcct ttgttgttac
     1561 aatatcgtct gtatcatcag gaatttgatc taaaaaaata acccttgaat gtttaaaagt
     1621 ggtataattt gaaataccat ttctagcaat acgatatcct ttttcaatta gttcattaat
     1681 tgtttcctcc gcaagtcctc cgcctgtttt atgccaaaag tctattgatt tattaaattt
     1741 tctaacataa ttatttctta acctcactgg tagcgttgat aaaagaaact gagtgtacga
     1801 cttccacgaa tgaccctttg gtaaagcaat tgatttatat cccattgctt tagtacgtcc
     1861 ataaatattc gaaaagttaa ctccttgaac acgtcccaaa agctttaccc aagtttcttg
     1921 atctattatt ctataaagat ttaggctatc aacagcatag tcttgaaaag gagatgcaac
     1981 tctcatttgt gatggtttta aacccgcttt atagaataga tcataaagtt cgttataaga
     2041 ataagaaaac ttatagtaag catgccatat gtcttccact gaccaatcat ataagggaga
     2101 tgctgtccag acatctttga attgtttggt aatccagcat tccttttgat aaccatactt
     2161 tttattgata aaaccactat atctgtgtaa ggattctgaa gcacggtttc ctaatataca
     2221 aactgttttt tgatttccgt gaatttgttt ataccaccta ccaaattgtt tcgctaaatc
     2281 ctcctgattc attttataac gataagtagt aattgaatta ttttccaaat taataacata
     2341 atcttgagat ggcattggtc ttacccagat atcttctgtt ttgtcatccc acggatacca
     2401 aaacatttca taactactaa gtgcagttct agtagccatc ggtaagcaca cccaatacaa
     2461 agaaactttt tttctacctt ctaaagaagt gaatgtttct tgaacatatt ttgttgttaa
     2521 actgtactgt gcttcaaaat cttgatgaaa cacacctatt tctctatccg gataatattt
     2581 atctctaaaa tccagtaaaa tattaagaag taacccacta tcttttccac ctgagaagga
     2641 aatatagaca ataggaaatt cattaaacaa aaaatgtaat ctttctatca atgcatcata
     2701 aacattttga tttaaatact ttttcactaa acttcctcat tatgcattta aaaatattaa
     2761 tacatagatt cactaagaat ctctttttcg agctttttgt tttttaattt ttcaagttga
     2821 ataattaaac cttgcttttc tttttcaagg taatagactc tactccttgt aagtctaact
     2881 tattcttaat cttatttatc gctcattttt taaattccga tgctctcaca gatattatca
     2941 ttgtttagtt acatgtctgt caatctattc gccaccacac taggggccat ctgattgaaa
     3001 aataaaattt cggagtccat tgtttgctca agaatcatat ctgtcacaat tacgtcatac
     3061 tctgaagaca gtgacaccat atcaaccatg gtcagcctca agtcatcaaa gttgataatc
     3121 tcaaaaaatc ctccaaaata ctcttttaag aagttgccaa cattgttata acttctctca
     3181 accactaata gtttcaagcg acgacgcgat tgatttgtaa gaaagagatt ttcccaggtg
     3241 aggaacaaac aaatagagga gatgattgat ggttctttcc tttaattcct tatgatcccc
     3301 agcaaataac tctttaacat aagcaacaaa ggtctggtat tgaactgggg gtttttgatt
     3361 tgtaaaggca ctatatttat aatgccttta tttaagggtt aactctaaaa atcagattgg
     3421 tcttttgctt ggcaatccgg acaaatcccg taagcaataa ctgggatacg cgtgacctta
     3481 taacctgttt gctcatgggc ttctttggca atatccataa catcaacatc cataaagtca
     3541 gcaatcttcc cacatatttc acaaaccaca ttgacgtgtt gatggcccat aaagtcatag
     3601 taggtggtta aatcattgct gattttcaac tctgagacaa aaccttcatc aactaaaact
     3661 ttcaaattat tatagactgt ggcaaggctc atgttaggaa agttaggctg taagtcacgg
     3721 taaatcttat cggcactagg gtgttctgtg gactgaatca tgtaagaaat aatggcttta
     3781 cgtgtctctg taattcgaat atgtttttcc cgtagatgct ctaggacatt ttcataggca
     3841 tctagggctt gctgatgtga atgaatgtcc ataagctgct actcctatcc ttttttcctt
     3901 tattatcacg cacgtctcta gtttcaatga tttgtgatgc attctggttt agcgactaat
     3961 tgcaaatagt ctatttttag gcagcgattc atcacaatag cctctttgcc tgccgaccgt
     4021 aaaatggttt gtgcttcttg gttttcaagg cctaattgcg cccaaaagac tttggcctga
     4081 cctgctaaaa agtctctggc aacttctggt aaaaactcac ttctgcgaaa gacatctaca
     4141 atgtcaacct caaagggaat tgccttgata ctggcataga ccttctctcc caaaataagc
     4201 tgacctgcta atttgggatt gactggaatg atccgataat ccatagcctg cataaatttg
     4261 gcgacaccat aagctgctgt gtctttgcgg tcagaaagac caacaaccgc aatggttttg
     4321 gctgactcca agtaagcttt taggacattc tctgagggat tttgaaacga ataaatcact
     4381 tgttccccta tctatttaat aacctctaca gctgttcaat atagcaggat aactcctaaa
     4441 gcatggcttc aatcactttt aaccttatcc gtcaaaaagc tcaaagcagc ttcatgactt
     4501 ctcctacaat tttttagttt attataacat aagttgtcaa aatgagaaat aacaagtaag
     4561 aaaacttatt tggcttcgta ccagctctgc ccagtacttt catcgacaca taaaggaaca
     4621 gctaaatcaa cagcagcttc catggtgtct ttgacaagtt tttttatagc agtcaactca
     4681 tcatttggca cttccaaaac gatttcatca tgcacttgaa gcagcatttt agctctaaaa
     4741 ccacctgctt gcaaggcctt atccagatta atcatagcga ttttgagaat atcagctgcg
     4801 cttccttgaa tgggcgagtt gatggctgta cgctccgcaa aagagcgaac gttgaaatta
     4861 cgagagttga tatccggtaa ttcacgacga cgcttaaaga gggtctctac atagcccttg
     4921 tctttagcct cacgcaccac attttccata taggctttaa tcccaggata gcgttcaaaa
     4981 taggtatcaa tgtaagactt ggcctgttta cgggtgatac caaggttatt tgacaaacca
     5041 aaatcagaaa tcccatacac aattccaaag ttaacagcct tggcattacg gcggtcattg
     5101 gcagtaacat ctgctgcctt gtcaatccca aacacacgca tagccgttga ggtatgaatg
     5161 tctgcccctt cattaaaggc agcaatcaaa tgctcatccc ctgaaatatg tgccagtacc
     5221 cgcaattcaa tctgtgagta atctgaactc aacaagacgg catcttcatg agatggggta
     5281 aaggccttac gaatcaaacg cccctgttcc aaacgaatgg gaatgttttg aagattaggg
     5341 tccacactag acaaacgccc tgtctgggtg agatcctgca catagcgggt atgaatcttg
     5401 ccatcagcca gaatataatc ctgtaaacca atcacatagg tggattgcaa tttagtaatc
     5461 tggcggtaat ccaaaatttt agccacaatt ggagcaatcg gtgccaaacg ttccaaaaca
     5521 tcaacagctg tagaataacc tgttttggtc ttcttagtca tctcaagagg tagttgcatc
     5581 ttctcaaaca agatactgcc cagctgttta ggcgaattaa tgttaaattc ttggccagcc
     5641 atatcataaa tctcttgggt gagcgcttca ataatgacct tgttttgctc tgccatatct
     5701 tgcaaagtcg ccctattaac cttgatccct tcaatttcca ttttagcaag gacattagcc
     5761 aaaggcaatt caatattctg atagaggtct agttgctcat gggcagtgag cttgtctagc
     5821 atttgagact tgctatctaa taatactttg accttacgag ctaagtgttc tagtaaaacg
     5881 tctttaacag gaacagcccg tttagcacct ttaccataga ctgtatcgtc ttcttccaaa
     5941 gagatgtcag taaaaatgcg ggcaatggtg ctaagctcat tgtcttctac agttgacaga
     6001 aggtaattag ctaatctagc atcatagcta ggtgctacca actcaattcc taagtggctc
     6061 aacaagacct tgctacgttt aaaatcataa gtagcaatgg gtttttggaa gacctgctta
     6121 aaactatccg tcgctaatag gctaaggtca gtggatgcgt aaatctgctc accatgtccc
     6181 caagcaaaac caatgatggc ctcacgatgg taattatccc gaagcgtttc aaagtagaag
     6241 atgtcttctg cgctaaacaa atcagcagac acattggtca cttcttgata ggaaagggca
     6301 gctactggct cttgagacat ctggctagca agacctttct tgagttgcac aaaatccatc
     6361 tcatcgtaaa attgagagag gctagcaaca tctggaccat tgtagacaat atcatctaag
     6421 ccaattgtga taggagatgc tgtattgata gtggcgagcg ttttagatag gaaagcttgg
     6481 tcacggtcat tgatcaagtt ttctttcatt tttgaggcct tgaatccatc aatatgctcg
     6541 taaatgcctt ccaaactacc aaattcatga aggagcttaa ggcctgtttt ttctccaatt
     6601 tttgtcactc caggaatgtt atccgattta tctcccatca aggctttgag gtcaataaac
     6661 tggtttggcg tcaagcccat tttttccatg aggtaagccg gtgtgaattc ttcaaattcg
     6721 gcaacccctt ttttagaaat ttcaaccacg gtattttcgt cagttaactg gatcaaatct
     6781 ttatcaccac tgacaatggt cacatcaaaa ggcacttctg tgcgctccgc cattttatca
     6841 agcgtcccga taatatcgtc tgcttcgtag tgttccaact cataataagc aatcccaagg
     6901 gctgtcaaca tctcacgaat ataaggaaac tgctcacgaa attcctctgg tgtcttggcg
     6961 cgacccgcct tataatcggc atacatttct gttcggaagg tggttttgcc cgcatcaaaa
     7021 gccaccagca cgtgagtagg ctggactctt ttcatcatgt ggtctagcat caaatgaaag
     7081 ccataaatgg cattggtatg aagaccacta tgatttttaa agcggtcaat ttgattgtag
     7141 agggcaaaaa aggcacgaaa ggcaacagat gagccatcaa ttaatagtaa tttattcttg
     7201 ttttccatag ccttattata acacagaggg acgggctttt ctcctttaag ccattggttt
     7261 tgctgataag taaatagtta acctaaaaag cctaggaaaa ttcctagact tctctatttg
     7321 ctatttagac aaaagcactt attttgtcca acttgatact ttagatttgt tagcctctac
     7381 ccattttttg gcggcagctt ctgggctcat gcctttattg atgtcaagca tgactgcttc
     7441 catatctttt tgggtccagt ggaacttatc aatgattttg tagacatttg gaagatcttt
     7501 tttcaagcct ttacgagcaa tggtattgat gttctcagtc gagccaaagg tttctttagg
     7561 atctttaagg tacttcaagt catacttggc aaacatccag tgtggtgacc aagctgtcac
     7621 gacaatagga tcttttttct tgatcgcttg atccaaggaa gtcgtcatgg ctcctgttga
     7681 tgccgccact aactcccaac tagatagatt atgatactct tttagagtct tttgggctgc
     7741 tgccatgata cctgcacctg gttcgatccc tgtgattttt tgatcggctt gtttgcttaa
     7801 gtcctcaata ctattaacat ctgtcatgta ttttggaaca gctaaaccaa gtttggtccc
     7861 ttttaggtta ggtcctaaat catctaattt tgacttgtat ttctgatact gttgcccatg
     7921 agttactggc aaccaagcac tagttgaaaa atcagcgttc ccatttgcaa cggtttgcca
     7981 cataacggca ttgtcaagcg gagtcaaggt cacatggtaa ccttcgtttt tcaaaacttc
     8041 tgcaatcaca tgagttgagg caacctcaga atcccactgc acgtaagcga tgttaacagt
     8101 ttcaccctta tctgccatac cagaagtcat agccataata ccgcgtccta aagcagctat
     8161 caaaaagaca gcaagggctg ctagaccaat ccatttattg gttttgccag ctttggcttt
     8221 ttcttgaggt ttgctattga acaactgtgt catacggtca agcacaatcg ctaagataac
     8281 caaggcaaga ccactgacaa atccactacc aatatcagcg tgttgaaggg ctgacaagac
     8341 ttcacgtcct aaaccaggag caccaatcat ggagcctgtt actaccatgg aaagggctaa
     8401 catcatggtc tgattaacac ctgccataat agtattttta gctaaaggca attccacttt
     8461 aaagagcttt tgtttcccag ttgacccaaa ggcatctgag gcctcaatca attctgttgg
     8521 aatgtcacga atggccaaat ttgtaaaacg aactgttggg ggcaaggcaa agatgactga
     8581 agcaaatact ccaggcacca taccaatacc aaaaaaggca acggcaggaa tcaagtaaac
     8641 aaaagccggc atggtttgca taaagtccaa aataggattc acaatctgac ggacagtggc
     8701 atttttagcc atccaaatcc ccagcggaat accaataagt accgaaatca aactagctac
     8761 taacaccaga gtaaaggtat tcattagctg cttccataac ccttgattgt aaataaagag
     8821 caatcctaac aaggtaaagg ttggcaaagg ccattttttc ttagcaagga aaaacatccc
     8881 tgctgttact agaacaataa aaagtaacgg gtggataaat aaaagtgttt tggtcatcca
     8941 atccatcaaa aagctaccaa ctacttgcat aatatcaaat agacctgaga aagttttagt
     9001 tagccactcc gttagctgct ccaccagttg agctactggt aattttgttt gtaatatcgt
     9061 ttccaaaatg catcactcct tttagttaag gtcttcgtct gagatattag ccaaggcttc
     9121 aatcactcgt cctcgaataa tgacacctag cagacgatta ttatcatctg tcactgcaat
     9181 cggagcagat gaatcataga taagaggcaa aatatctgta ataatagtat cttttgagac
     9241 agttctcaca tcgcgatcaa tcacttctga tagcggtaac ccttttttgc gcgcctctat
     9301 agcggcatcg gccgtcaaac taccgactaa ttggcggcgg cgattcgtcg ccatcaacat
     9361 agacacctct tcgttgtgca tacggttcaa ggcaacttga ggtccatcta attcaacagt
     9421 agttgttaac ggtttgatca tgatattttg tgctgtcaag actttagaac ggtccacatc
     9481 ctcaacgaat tcacgcacaa agtcattagc tgggttagtc aagatttcct caccagtacc
     9541 aatttgcata atttgtccgt ctttcatcaa agcaatccga tcaccaatac gcaaagcttc
     9601 attcaagtca tgactgataa agatgatggt ttgtttcatg ctatcttgca aatcaagtaa
     9661 ttcatcttgc atctcacgac gaatcaaagg atcaagcgct gagaatgcct cgtccattaa
     9721 gagaatttta gggctattag ctagcgcacg ggctaggccg acacgctgct gcatcccacc
     9781 agatagttgg tttgggtact ggtctttaaa atctaatagg cctgaattat caagggcttt
     9841 ttctgccaat cgctggcgtt cttctttggg aacgccacgt aattccaaac caaattcggt
     9901 attttccaaa atggttttat gaggaaagag ggcaaagctt tggaaaacca tgttaatgtc
     9961 atggcggcgc acctcacgca gctgatctgc tgacatggtt gagatgtctt taccttccag
    10021 caagatagat cctgctgaag gttcaatcaa acgatttagc atgcggacaa gggttgattt
    10081 cccacttcct gatagcccca taataacaaa gatttcacct tttttgacct caaaactagc
    10141 gtcatagaca cctacagtag cgcctgtttt cttaaaaatc tcactcttat ttttgccagt
    10201 ctttaccatc tcaagagctg ctttttgttt tttgccaaaa attttactga gatgtttgac
    10261 ttctaaaatt gtttccattc gttttttctc ctaggtaatc gtttatcatg tgaaatagtg
    10321 acatagcttt ggcgaaatat tagccaatat ttaacaaagt agctctacac aattaataaa
    10381 cgtgtggtca cttttttact taaaaaaaga atctgccgga acagaacata actatattat
    10441 cacgtgtggt cactttttgt caaggacaat aactcgatct ggtaatgcca caatgatagg
    10501 tgatcgcttt cattctttta ggtatggtct tttaaccagt acaatttttt atcacaactg
    10561 atgactattt ctttgctgat taggctattg ttacattaga aatccttctt ttacctataa
    10621 tatctctttt gcggccatcg taaataacga ccacggtgac tcttaaacat ttgctcatct
    10681 ctccaaaaaa actcacctaa gacagtgtcc tatgaagcga gttagcttaa tcaggcacta
    10741 tcatcttagg tgagtagggt gttgcttata gtaaagcttt aaattggata ttagaatctt
    10801 ctaagaagca gtcatcaaat ccacgaggat gatggtattc gatacgattt tggtcttgtg
    10861 gataggtgta cttgccacca acctcccaga taaagggatg gaaatcgtat tggagacgtt
    10921 ctttgcgcat tttccacagt tcaaggattt catctgttga tgccataaag tttgaccaaa
    10981 tgtcataatg aactgggata acgactttag cacggagatt ttctgccata cgaagaaggt
    11041 caacagaagt catcttgtct tgaatcccaa ttgggttttc cccatagtta tttaacacaa
    11101 cgtcaatatc ataatcacgt ccatgtttag caaagtagtt cgaaaaatga gaatccgcac
    11161 cgtgatagat ggtaccacct ggtgtttcaa aaatatagtt aacagctttg cgagccatgt
    11221 catcatctgt gatagctaaa cctgctaaat caccatcttg agcatcagct ccttgtattg
    11281 ggagagttac cagacaggtg cggtcaaacg actctacagc ggtgatctta atatctttga
    11341 attcaaagct atcacctggc tttaagatca taatacgatc ttttggcaca ccccaatttt
    11401 tccaaacttc accacattca taaggtccta caaatttaac atgattaagt tttgggttat
    11461 taataatggc tgccgcagta ttgatatcga tgtggtcact atgataatga gaaaccaaat
    11521 aataatccaa ctcgttaatc ataaatggat caatcaccat tggttgggcc ctaagattgg
    11581 gctgtaattt acgagctcct gccatattag ccatttgatg tccacgaacc atatccttaa
    11641 cttgcttggt cgctttccca cgatttgacc ataagtccat gacaacatta gcaccgcctg
    11701 gtgtcttaat ccagatacca cagtttccta accaccacat cgcaaagttg tcagctggta
    11761 cgacttcttg ctcgatttct tcatttaacc atgttcccca ttctggaaac gtgttaagga
    11821 tccatgattc acgtgtaata tcttgtactt tagtcattag ggtttcctcc gaatttgttc
    11881 ttcgtttcta tactttaagt atagactttc ttgtcaatga taaaaagacc aagtgtcaca
    11941 cagatctgtg ttcaaaagtg gactgacttt ttcattagct cagtctaata ctgtctcatt
    12001 ttgcacactg tatctcgcat ccatactgta ttcaaagcta tattaaaaac ctcagttata
    12061 tttttctatg tcatagaaaa ctgaggtact ttgacgactt aacacttact catagcagct
    12121 cgcgatgaat gagtttttca attttagaaa ccaaggcata acgatctgat tcatctttta
    12181 caacagcttc aatagctttt gtgagctctg tagaaaagcg ggagtgctca ctcaagcgtc
    12241 cttgctttga aaagcgtatc aatttgatga tatcatcgtc acttaaaata gggttaacaa
    12301 taagcatcgg gattttagtc tttagcgtat ctgtagtagc aacaatcata tcgactgcta
    12361 aaagatcgta aacactctga tactgttctg tcgtaaaaac agcttcaatc tgaccatttg
    12421 ctagatacct ttgacactgt ttgaacaata acttttgaat gcctatccca tcatctgaaa
    12481 caataacgag tttggtcttt tcttgctctg tattattgtg acgcagctct cccccgagat
    12541 ggatagtcaa gtaggcaata tcatcgtctg tcaagctaat catccaatct tgttccaaaa
    12601 tagtggcaca agattgagtc atagcaaaca attcttcgta tttttcttta atatggtctg
    12661 ttaagggatt aactaaaaaa atcccataag ctttacggta aacgagcgcc ttacagtggg
    12721 tcgtcaactg cttcagcaaa tcctgtttat gcgtgaaatg taactgataa cggctctcca
    12781 actggtcaat aaagtgacta atggttgctc gcatgtcatc ataatcttga ctttccacgt
    12841 gatgatcttg atcttttcga aaagacaaca tcaacatcgc taccatacta acttcgatat
    12901 catccaaatg aagcttaaaa ttatggtaaa gctctctagc taagtcctga gcaatgtgat
    12961 attctttacg tttccaaatc aaatgaaatt cttgtttaag agcagacttt gtttctgaat
    13021 caagacgcat attacgataa cttaaaagca tgaaaggtaa aatctgcaac atgaattggc
    13081 tatcttgggt attaattgtc tttcctaagc tagcttgaga taaaaaaaga tactcatgaa
    13141 aataagtcaa aatatcttta gaaaaataaa ccgataagcc ttgtatctct gagagtttac
    13201 ggttgaatat atcaataaag ctagtattgc caccttggta aacgtccact aacaatttgt
    13261 acaggtattg aataagagcc attggatgac aaccaaaata atatccccta gcctttgtcg
    13321 catgaagctg aatcttgtat tgtttgtctt ccagttcttc ccttaactca gtcaggtcat
    13381 ttaaaatcgt gttacgagac acatcattga tctgcatcag tttatcaatg gtcacgcgct
    13441 cagtggaaac cgcaatataa atcgaggata ggcgtctgcg ctcatcactt ttcatgacat
    13501 aattataatc agtcacttct tctaataata agcgacaagc agctttttga tccgccgtta
    13561 aaagaatgcc aagtctagga taagagataa tctgatctac tccctttggc aaagcctgat
    13621 taattttgtc aagctggtaa taaactttac gacgtgactg atttaaagca tgagaaatgg
    13681 ccataactgt ctcaggtgtt tctagtttaa gtaaataaga cagcaagtca taactctttt
    13741 tatctaaaat catcatgttt acaaacctcc tctctgaaaa tccatccttg cttattttat
    13801 catgatttca gtgactgcgc agccaagttt ttaaaaactc accataataa gattcactta
    13861 atatgattcg agctaatcac ctcaactgat ccaacaccaa caccttatat ctggtctcta
    13921 agaactccac aacatacggt tcatccagtt tgtgctcatt ggcgtttaaa cagttcatcg
    13981 aaaaggacaa gtcaaaagga cttgcccaaa caatgattaa caaaaccttg aactttttgg
    14041 cttctagtga gaacctgtgc taataagcca tatcgcgacc tcatttttga ccgtaataag
    14101 catttggacc atgtttacgc aaataatgct tatccataat gtatcgtggc gctggctcta
    14161 cgcgtggatt gatttgttct gtcaagcgat tcatcctagc cacttcttct aagacaaccg
    14221 agtggtaaac ggcttgctct ggggttttcc cccacgtaaa tgggccatga ttgcgaacca
    14281 cgattcctgg aaccgccatc gggtcaagac ctcgcttgct aaactcttct aaaatcacgt
    14341 tgccagtttc ttgctcgtaa gccccatcaa cttctgcttt tgtgagagag cgagcacaag
    14401 gaaccgggcc ataaaaatag tcagcatgcg tagtcccata aaacggaata tcacgacctg
    14461 cctgagccca accaacagct tctgtggaat gagtgtggac aataccgccc acttctggcc
    14521 aagctttata aagttccaca tgggttggca gatctgaaga agggttcaaa tcaccttcga
    14581 ccacattccc atcaaggtct gtaacaacca tattttctgg tgtcaagagg tcgtagtcca
    14641 ccccagaagg cttgatgaca atacgtccta attcacgaca aacttcagag acattgcccc
    14701 acgtaaattt gacaagaccg tgttgtggta gagacttgtt agccgcacag acacgttcac
    14761 gcatttcttg caagtttttc gccatattat gtcaaccccg ctttctcaat aagtgggtaa
    14821 aggaagtcct gagcttcttt gatagcagct tttgtttcct ccaccgtgtc acaattttct
    14881 gaccacattt caatcaaaaa aggcccattg tagttggttt tcttgaggac cgcaaacagc
    14941 tcttgccagt ccacacaacc ttgaccaaat ggcacatcac gaaactgccc ttttgaggtt
    15001 tccgtgacag cataagtatc tttcaagtgg agggctgcaa tggatttgtg cccattgtaa
    15061 aattcactcc acaaatcatt atgccaggca gaaacattgc ctgcatcagg ataaacaaag
    15121 agataaggcg agtcaatctc tttttcaact gccaagtatt tttcaataga gttgataaaa
    15181 gggtcatcca taatctcaat agaaagcatc acttgggctt cttcggccca gtcacaagat
    15241 tgtctcaagt ttttgataaa acgagcacgg gtttcaggcg atttttcttc atagtaaacg
    15301 tcataaccag ctaattgaat ggtacgaacg cctaagtcct gtgccaattc aatacattgt
    15361 ttcatcagtt taagagactt ggcttcagta gcagaatcat ttgagcctag tgggtaacgt
    15421 ctatgaccag aaaaacaaat ggtcgggatg cgaatgcctg tttcataaat ggctttcact
    15481 aaatcaagcc gttcttcctt agtccactct aagcgcgcta agcgagcatc tgattcatca
    15541 acagacattt ccacaaagtc aaaacctaag tcttttgcaa attgcaagcg ttcacgccag
    15601 gtaaactgtt ttggagttgc tttttcataa ataccaatag gacgcgccat aaagttaccc
    15661 ccagatacgt ttgatttcat ctttgaaggc acgcgccgct gcagcaggat cttctgcttc
    15721 agtaatgcct cgccctgcga taaaggtaaa gacatccacc ccttcaaaaa gtttcaaagt
    15781 gtctacatca agcccaccag ttactgagac acgaaagccc atgtcaatca atgttttcac
    15841 cttgttaagg tctttttcac cccaagtttc tccagcaaga agggcatcac gagattggtg
    15901 gtaaatcgct tgggaaatcc cagcgtcaag ccataattga gcttgctcat aagtccaatc
    15961 accataaagt tcgatttgaa tttccccacg gtctccgcgc acttctttta tggctttgag
    16021 ggctgcttcc atggttggaa tcgtcgcaca gcaaatgcag gtcatccagt cagcaccacg
    16081 ttttgcattg tttttagcga ccgtgccacc agcgtcagca catttggtat ctgctacgat
    16141 aattttctct gggaagaggc tgcgtaatac ctcaaccaac tcgcttccca cttgaagcaa
    16201 acaaacggta ccagcttcaa tcacatctac ttcgtgaccc acagcaacgg ctgctttaac
    16261 agccccctgt aagtcagaat ggtctaaagc aacttgtaaa tttggaatat gtgtcatctc
    16321 tttttcctaa aactcttagc caccgtgcaa actggttaag agttcttatc ctttccatca
    16381 ttcgttagta tcctgtgtaa ggaaagctta agcattcaag tccatacctt ctaagtaagg
    16441 actatcttta gattcttcta ccatttctag aacctcttta ggactttggc aggccaccaa
    16501 gcgttcaatg gcgttatcta gttcaaacaa ggccacaatt tgtgggatag ccactgttgt
    16561 gtgaatagaa gggtctgtag cggccaacgt caaaagaaca gaaacctctt taccatctga
    16621 gaaggtgact ggttttgtta gtgtaatcaa agcaaatgca ttgcgattaa cgcctaaacc
    16681 tgcttctgca tggggcatag ccatacctgg catcaacaca taataaggtc cgtatttttc
    16741 tgttgatgca atgatggcgt cgtagtaagc tgacgtcact gctttgctat caatcaaagg
    16801 ttgaacagct aatcgaacag cctcttgcca agtatcagca cttagcccca atcggatgga
    16861 gttgttgtca ataaaggctt gttttaaatt cataaaaact atctctttct agtgtcttgc
    16921 tttgcaacac acaccatttt tactagtttt atcctactaa agagaaagag ctgaaaacct
    16981 tcgtcacaac tccttcgttt tgattcagaa ttagcttata gcacttcttg tagtttggtt
    17041 ttaatttcat tatcatccat caggttatca agaccaacca agtggccttt ggtacgacca
    17101 tcaagctcat gaatcaagtg gtttgatgcc actacaatat cataaccaga agctagacct
    17161 ttagcttcac caactgagca agaagctgac tgaatatctg tcacaccaag ttgacgaagc
    17221 gcattttcaa ctttcatttt gatcaccata gatgacccca tgccattgcc gcatgctgtt
    17281 aagactttaa ccattgtttt ttcctccgaa aatgttttat tattgttttg ttaaaatagc
    17341 agagctattt cttaagatgc agtgttattg agcttcccca cggtagtaag cttctttgtc
    17401 cttagctttt gcgaattgca attgtggaat ggcaagtaag aagatgcaaa caagcacata
    17461 ccctgcaata ccaaggaatt tgaagaggta cccaaatggt aaccatggaa gaaccaagtc
    17521 gatattaccg tgataaccac ctgtaagtcc taaaagacct acagcaacag caccaagtgc
    17581 cacctgaata atacctgaga taaatgacaa tgctaccgct gctttccagc caccacgttt
    17641 atctgcataa accgcaattg ccgcattatc aaagaatacg ggaacgaatc ctgtgataat
    17701 taagattgga tttttaaaga taacaagaag agcaatggtg attaattgac caatcaaacc
    17761 aaaagcaaat cctgaaagca ccgcatttga agaaccaaag ccataggaag ctgcaacgtc
    17821 aaccgctggg aatgaccctg gaagcaattt gcttgagatc ccttgaaagg cattggtcaa
    17881 ttcagaaaca aacatgcgaa caccctgcat caagataaag agataaactg agaaggtgag
    17941 agaggtttgc aaaatataca tgaagaaagc ttgcttagct gggttgaatg ctccaggtcc
    18001 gattaagtcc acatcagaca taatgtctgg accaaggaca gccaagatag ctccgaaaaa
    18061 gaccaacatc aaagttgctg acgcaacaac agtatcatgg aaaatgttta agaaggttgg
    18121 taattttagg ttatcaaggt tttcttcttt tttaccaaag aacggtgcaa ccttatccac
    18181 aaaccaaatc gcaaattgtt gttggtgacc aatcgcaaac ccaccgccac ctgtaaggcg
    18241 ttgagttgct tcaacggtca tgtttgagct gatagcccag taaagcccac agatgatacc
    18301 gactgcccat gccccaaaag cattttggaa ttgagggatt aaaagaagga caaagaccga
    18361 aatcgtcgct gcctgttgga ccatgatgtg acctgtgatg aaaagggtac gaactttagt
    18421 gaccttgcga agtgcaacca aaagaatgtt gaccccaaat ccaatcaaga gagctgtcgt
    18481 agcaacactg atgaagccca tctcttctaa cttagtatta gcagcagcca aaccaaaata
    18541 aggatcaata acggcggctt tcaattcaaa tttcttagca agagcaacca agatcggacg
    18601 aaaagtcgtt acaagaccgc ctgctccaac gttcaaaatc aagtaaccaa cggtagcctt
    18661 tacaaaacca gcaaagactt cataaatggg ttttttaagg agtaaatacc cgattaaaac
    18721 caaaagacct acaaagaacg ctgggttttg caaaatattt tgcgagaacc agtttagggg
    18781 agctaggagc atttccataa gaactacctc ttttcaaagt taataaagat aaagtgttta
    18841 tatgttcatt ataggtaatg aaagcgtttt aaaaaagacc aactatcaca caaagaagtg
    18901 ttcaatatta gacttaagtt aacttatttt aaaatttaac tacacttaat aataaggaga
    18961 aaatatccct aaacaacgat taaaaaccac aagaacgaag gttcttgtgg tttttctaga
    19021 taaattgctt tttgaataga tcagctcttt ggcattaact gtgacgtgac gcaaataacc
    19081 attgaagggc tgtgtcacct caaactattt gataacaata ttaacgagtt tgtttggtac
    19141 tgcgatgact ttgatgatgt ctttgcctgc gatttcggct tggacttttt cgttagcaag
    19201 agcaacttct tgtaattctt cgcgtgaaag gtctttagca acgacaagtt tagctttgac
    19261 cttacctttg atttggacaa cgatttccac atcgttttca accaatttgc tttcatcata
    19321 acttggccat ggcacgtaag agattgactc acctgaggct gtcaaggctt gccagagttc
    19381 ctcacctaag tgcggtgcaa atggtgcaat caattgaaca aagcctttga catagtcgct
    19441 aaagagtttg gcttccttgt tggctgcgtt gacaaagacc atgagttgag cgatagctgt
    19501 gttgaatttc atttggtcaa cttgctcagt aacagcctta acagtttcgt tgtaaacctt
    19561 gtcaagggct ccgctatttt cttcagtaat ctctttagtc gtgatcaaac ggtaaacacg
    19621 gtccaagaac ttacgtgagc cttcaagacc ttcttcagac caagcgatgg aagcatcaag
    19681 tggtcccatg aacatctcgt aaacacgaag ggtgtcagca ccgtactgct caacaacatc
    19741 atctgggttg acaacgttct taagtgattt agacatctta gctggtgctt gttccagctc
    19801 ttcaccagtt tccacatgga agaagctgcc atcacgtttt tcaaccttgt cagtcgctac
    19861 aagcgctcca cggctgtcgc ggtagcttgt tcccaaaatc atcccttggt taaagagttt
    19921 ttggaatggc tctttggttg gtacaacacc gagatcgtaa agaaccttgt gccagaagcg
    19981 agcgtagaga aggtgaagca cggcatgctc tgcaccaccg acatagatat caactggcaa
    20041 ccattgtttg aggagttcct cgtcagccag tttttcagtg ttgtgtggat cgatgtaacg
    20101 aagataatac cagcttgaac ctgcccattg tggcatagtg ttagtctcac gacgaccttt
    20161 cacaccatct tcacgagtca cttccaacca gtctgtcacg ttagcaagtg ggctctcacc
    20221 agtacctgaa ggacggatat ccttcgttac tggaagaacc agtggcaact cactctcagg
    20281 aaccgctgtt gaggtcccat cttcccagtg gatgattggg attggctcac cccaataacg
    20341 ttgacggcta aagagccagt cacgaagacg gtaagtgact ttctcattac cgacgccttc
    20401 tgcttcaagc cattcgacca ttttggcaat agctgacgct ttgtcaagac catctaggaa
    20461 gcctgagttg atgtgaagac cgtcttctgt aaaggcagcc tcttcaacat taccaccttc
    20521 aagaacaggg atgatgtcta gcttaaattg ttttgcgaat tcccagtcac gttcatcgtg
    20581 ggctggaaca gccatgatag caccagtacc gtagctggca aggacatagt ccgcaatcca
    20641 aactggcatt tctttgccgt tgaccgggtt aatagcgtag ctacctgtcc agacaccagt
    20701 tttttctttg gcaaggtctg tacgagcaag gtctgatttg agacttgctt gacgtttgta
    20761 gtcagccacg gcttctgctt ggtcagctgt cgtaatagca tcaaccaagg catgctcagg
    20821 agcaagaacg gcgtaagttg caccaaaaag ggtgtcagga cgtgttgtaa agacagtgaa
    20881 gtccttatct gtatccttaa ccttgaaggt tacattggca ccagttgatt taccgatcca
    20941 gttgcgttgc atgtccttga ttgactctgg ccagtcaact tcttccaagt cttctagcaa
    21001 gcgctctgca taggcagtga ttttgagcat ccattggcgc atgggttttc tgacaactgg
    21061 gtagccgcca cgttctgatg tcccatctgg aagaacctct tcgttggcga tagctgttcc
    21121 caattcttca acccagttaa cgggaacttc agcttcgtag gctagacctt tttcataaag
    21181 cttggtaaag atccactgtg tccacttgta gtagttaggg tcagttgtgt taacttcacg
    21241 atcccagtcg tatgagaaac caagagcatt aatctggcgt ttgaagttag cgatgttttc
    21301 agctgtaaac tcggctgggt cattaccagt atccatagcg tattgctcag caggaagtcc
    21361 aaaggcatcc caacccattg ggtggaggac attgtgacct tgggcacgtt tgaaacggct
    21421 gagaatatca gttgctgtat agccttctgg gtgaccaacg tggagaccag ctcctgatgg
    21481 gtatgggaac atatctaggg cataaaactt aggttttgat gcgtctgttc ctgttttaaa
    21541 ggtgtgatta tctgcccaaa aggcttgcca tttgggttca atagcggtgt gatcgtaaaa
    21601 tgtcatgtga aatctcccat gtaaaaaatc tagtcttctt attatagcat gagatgaagc
    21661 ttttaggaat ggtcaagaca tgactagcac cttggctttt gagacttcag acgattagct
    21721 atttttaaac cctgctttag catcaaccat cctcacaaaa agctaataaa aaagccagac
    21781 ttgctctgta aacagagcca atctggacaa gtagacttaa aaagcaagtg cttgctcaaa
    21841 atcggccaat aaatcttcga tattttcaac accacaagac aagcgcagca aaccatcaac
    21901 aaccccttgt tccaaccgcg cttgtgacga taaacaagca tgagacatcg ttgctggatg
    21961 tgacaaaatg gactctactc cacctagact aacggctaaa atcggcaact gaatacgatg
    22021 ggtaaaggtc atcagctcct ccttagaagc caactcaaag gataaaacag caccaccatt
    22081 cttagcttgt tgcaggtggg tatcgtgatt aggatgactg tctaagccag ggtaatgtac
    22141 cttaagaact ttggggtgct tcgctaaata gttagcgagc tgctgagcat tttttaccgc
    22201 ttgttccata cggatcccca tagttttcat gccacgaaga atcagccaag cgtcttcgac
    22261 cccaacaatt gctccaaagt ttttttgaaa aagcttgagc tggttgtaga tagcctcatt
    22321 attggtagca gctaaaccag ctaccacatc actatgacca ttgataaatt tggtcacact
    22381 ttctaccaca atatccacac ccatagctaa gggttcttga tacaaactgg tcataaaggt
    22441 attatcagcc acagttagca caccataagc tttggcgagt tgcacaagct ctgaaatatc
    22501 acaaattttc aagagcggat ttgacggtgt ctgtagataa atcatacgcg tattaggcct
    22561 gatacttgct tttactgttg ctaaatcagc catatctaca aagcttgttt caatctgata
    22621 attgggtaaa atagctgtcg caaattgaca agtccctcca tagacctcca atgggaaaat
    22681 cacatgatct ccagctttta agagcatcaa aacagttgaa atagcagcca taccagatgc
    22741 ataagccacc gcataagttg ctttttctaa acaggctaac ccgtcttcta aagcttcagt
    22801 cgttgggttt gaaaagcgtg tgtacaaatg tttttgacta ggacaataca gttctgaatt
    22861 gtggaacgtc gaagtctgat agatgggaac tgaagctgct cctgtaaact cgtcaataac
    22921 cgtatagcca tgtaataagg tcgtattttc tctcatttcg tgcacctctg caatagcgtt
    22981 aactccaatg aactctcttt tagacaatgg tcccacccca atggttgcac aaaccaaaaa
    23041 gctcttcaaa aaagcgtgat ctgctaacct ataagaaaag tagtgggcac cttttaaatg
    23101 gacaatgaat ttttccaaca atatcatttt tagatcgatt acgtttatta tacaaccttt
    23161 agctaagttt gcaagccctt ttatcatctt tgaccaagct gccaacacct ctccagcaag
    23221 ttaaagtata gctacctttg gccccatcgt ctcaaaagct tagcttatca cactgacagt
    23281 cctactttgc atcgtcacct actcaatagg gcaatattgc catcaaactt tcattaaaag
    23341 gtcacaattt atttcattta atgagaaaca gaacttgttt tcaccatgcg tcttatagta
    23401 cactgctaaa gtactattta tttttaggag agaaatatag tgaaaaacaa attattttta
    23461 gttgcccttg cgaccgtaac tgtcctaggg ccctctttag caacccctcg tcaccagacc
    23521 gtgcatgcgg ctaacgtctc acctgcaggt acatgcacac atccgaaaga agattcaact
    23581 attagcgttt gctatgagag cacagatggc acttccgaag aagaagaaaa gactgttaaa
    23641 actacaacaa atagtgattc attcttaaca tggctttgga caacaataac aacttggttt
    23701 tcttcattaa tgaataaaat gggaattagc taaaacaaat tcacttatga atgttaaaca
    23761 gttctcatag ccaattatca acaaccatct cgtggcggtt ttctaatcct agatcgccac
    23821 acttcttatt cagataaata ataataaaaa cattaaaaca acacttgatt tattaacaaa
    23881 aagttagtat aatatagtca tactacaaat taaaggagtt atc
//
LOCUS       DAUGSW010000024        20693 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUGSW010000024 DAUGSW010000000
VERSION     DAUGSW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20693
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.024"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(115..1251)
                     /gene="dnaJ"
                     /locus_tag="VIB18_001139"
     CDS             complement(115..1251)
                     /gene="dnaJ"
                     /locus_tag="VIB18_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEQ8766150.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(1532..3358)
                     /gene="dnaK"
                     /locus_tag="VIB18_001140"
     CDS             complement(1532..3358)
                     /gene="dnaK"
                     /locus_tag="VIB18_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEQ8766151.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(3539..4111)
                     /gene="grpE"
                     /locus_tag="VIB18_001141"
     CDS             complement(3539..4111)
                     /gene="grpE"
                     /locus_tag="VIB18_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEQ8766152.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(4114..5148)
                     /gene="hrcA"
                     /locus_tag="VIB18_001142"
     CDS             complement(4114..5148)
                     /gene="hrcA"
                     /locus_tag="VIB18_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEQ8766153.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILSEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(5283..5852)
                     /locus_tag="VIB18_001143"
     CDS             complement(5283..5852)
                     /locus_tag="VIB18_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8766154.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(5849..6592)
                     /locus_tag="VIB18_001144"
     CDS             complement(5849..6592)
                     /locus_tag="VIB18_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEQ8766155.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDSQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGT
                     SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            complement(6582..7289)
                     /locus_tag="VIB18_001145"
     CDS             complement(6582..7289)
                     /locus_tag="VIB18_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8766156.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEEQSDEI"
     gene            complement(7682..7921)
                     /locus_tag="VIB18_001146"
     CDS             complement(7682..7921)
                     /locus_tag="VIB18_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8766157.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(8136..8351)
                     /locus_tag="VIB18_001147"
     CDS             complement(8136..8351)
                     /locus_tag="VIB18_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766158.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTAYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNHHVCLHYY"
     gene            complement(8348..9787)
                     /gene="gatB"
                     /locus_tag="VIB18_001148"
     CDS             complement(8348..9787)
                     /gene="gatB"
                     /locus_tag="VIB18_001148"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEQ8766159.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLLD"
     gene            complement(9787..11253)
                     /gene="gatA"
                     /locus_tag="VIB18_001149"
     CDS             complement(9787..11253)
                     /gene="gatA"
                     /locus_tag="VIB18_001149"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEQ8766160.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(11253..11555)
                     /gene="gatC"
                     /locus_tag="VIB18_001150"
     CDS             complement(11253..11555)
                     /gene="gatC"
                     /locus_tag="VIB18_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEQ8766161.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(11787..12122)
                     /locus_tag="VIB18_001151"
     CDS             complement(11787..12122)
                     /locus_tag="VIB18_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
                     /protein_id="HEQ8766162.1"
                     /translation="MKDRYFFCDVVGKYLEEYVDRGIFDKEPFQTFDQKGIGRLFSTA
                     VSLGRSVKSKLKLGICGEHGGDPASIAFCHSQGLTYVSCSPFRVPLTRLAAAQAAIKA
                     SGHSLTQDK"
     gene            complement(12566..13120)
                     /locus_tag="VIB18_001152"
     CDS             complement(12566..13120)
                     /locus_tag="VIB18_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEQ8766163.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSHMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(13267..14049)
                     /gene="codY"
                     /locus_tag="VIB18_001153"
     CDS             complement(13267..14049)
                     /gene="codY"
                     /locus_tag="VIB18_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEQ8766164.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(14267..15481)
                     /locus_tag="VIB18_001154"
     CDS             complement(14267..15481)
                     /locus_tag="VIB18_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8766165.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            15712..16164
                     /locus_tag="VIB18_001155"
     CDS             15712..16164
                     /locus_tag="VIB18_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEQ8766166.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(16287..17675)
                     /locus_tag="VIB18_001156"
     CDS             complement(16287..17675)
                     /locus_tag="VIB18_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8766167.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGVAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDVEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            17747..18712
                     /locus_tag="VIB18_001157"
     CDS             17747..18712
                     /locus_tag="VIB18_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEQ8766168.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQNIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(19061..19765)
                     /locus_tag="VIB18_001158"
     CDS             complement(19061..19765)
                     /locus_tag="VIB18_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766169.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(19778..20680)
                     /locus_tag="VIB18_001159"
     CDS             complement(19778..20680)
                     /locus_tag="VIB18_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766170.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
BASE COUNT         6285 a         4358 c         3583 g         6467 t
ORIGIN      
        1 tttgacaaga gaaaaaacga tatctataaa agaaaacgtt ttctataact gttttgacat
       61 aaaaaaaacg tataacttcg ggaaaattat cctgagatta tacgtttgac atctttaaat
      121 atcctctaag gcatctttca ctttatcaaa aaaacctttt ttctttggat gtaacatttt
      181 ttcaccactc gcttctgcaa atgcttgcaa ggcttccctt tgagcgtcat tgagtttggt
      241 tggggtcaca atattaacgg taacatgttg atccccttga cctccaccac ggagttttgg
      301 tgctcctttg cctttgagac ggaaggtttt acctgtttgt gtcccagcag ggatagccat
      361 ctcaacatcg ccatgaaccg ttggaatttc aacagtatct cctaaggctg cttgagtaaa
      421 agaaatatct aagttgtagt aaatagtgga accattgcgt tcaaattgct tacttggtaa
      481 gacattcaaa ataacaaata aatcaccata aggtccgcca ttaaagccag cttctccttg
      541 accttgtaaa cggatttgct gaccagtctc tacaccagct ggaatcttaa cagacacttt
      601 atgagcttgc ttttcatgac cagtaccgtg acaggtttga cagggttctt taatttcctt
      661 accactacca tgacaaatat cgcaggtgac ttgtcgacgc atcataccaa gtggtgtttg
      721 ggtgtcaatt gtcattacac ctgaaccatg gcacttacga caagttactg gagcggtacc
      781 aggttttgca cctgagccta aacaagtgcc gcaggttgct tcgcgattat agctaacttc
      841 tttttcaaca ccaaatacag cctcttcaaa agataaatta acacgatatt gcaaatcgtc
      901 accttgacga ggggcatttg ggtttcggct tccaccgcca ccaaagaagc ttgagaagat
      961 atcttcaaaa ccaccaaagc cacctccgtc aaaaccacca aagccgcctg ctccgccacc
     1021 aaagccgcct tgagcacctg cagcgccgta ttgatcataa gcagcacgct tttgtgaatc
     1081 acttaaggtt tcgtaagctt cttgaacatc cttatacttt tgctccgctc cagcttcttt
     1141 attgatatct ggatgatatt tcttagacat ttttcgataa gcttttttga tatcgtcctg
     1201 agaagcgtcc ttagaaaccc ccagacgatc gtaatattct gtattgttca taatgtaaga
     1261 taccaagccg taaaacgact caatgaaaaa taggaaatcc aacaaagata ctctcgtatc
     1321 taggaggtat ttctcttttt tcgcagagtc gtaggcgtgt tcgaatccgc aaaagagtct
     1381 ttacacgctt tagcctgtgt tcgaataatc gaacttgtat tcctttctta aaatattttg
     1441 acgtcagcat ttttacattt tatttagcca aaaacagagg tttggtacaa cctctgaatt
     1501 cggatattaa tgttactaga taactaaatc attacttttc tgtaaattcg ccatctacaa
     1561 catcatcatt atttgctgaa tcattagctt gtgcaccttc tgcaccttgt gctgcctgtt
     1621 gagctgctgc agcttgctcg tacattttaa cagccaaagc ttgcgctttt tcatttaatg
     1681 cttcaagttt agctttcatg tcgtcaaggt tgccagattc ttgcgcagct tttaactcgt
     1741 caagagctga ttgcgctgca tcgcgttctg tatcaaagcc tttaccttca gtttctttga
     1801 ttgttttttc agtagcaaag atagcttggt caacttcgtt tttaaggtca acttcttctt
     1861 tacgtttcgc atcggcttcg gcattagctt cagcgtcttt catcatgcga tcaatttctt
     1921 cttcagaaag tccgtcgttt gatttgataa cgatgtgttg ttccttttgc gtaccaaggt
     1981 ctttagcttt tacagaaaca ataccgtttt tatcgatatc aaatgttact tcaatttgtg
     2041 ggattccacg aggtgcagct gggatatcag tcaattggaa gcgaccgagt gttttgttat
     2101 ctgctgccat tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg
     2161 ctgctgttga gaagacttgt gatttagatg ttgggatagt ggtgttgcgg tcgatcaatt
     2221 tagtgaagac accacccatt gtttcaatac caagtgacaa tggtgttacg tcaagaagga
     2281 caacgtcttt cacatcccca gtgataacac caccttggat agcagcaccc atagcaacca
     2341 cttcatcagg gtttacagat ttatttggtt ctttaccagt ttcagctttt acagcttcga
     2401 caactgctgg gatacgagtt gatccaccaa caaggataac ttcatcaatt tctgacaatg
     2461 acaatcctgc atctgaaagg gcttgacgaa ctggagtttt cgtacgttct acaaggtcgc
     2521 gagtgagatc gtcaaattta gcacgagata agctcatctc caagtgaaga ggaccagcag
     2581 aaccagcagt gataaacggt aagctaattt gtgtttgtgt cacacctgaa agatcttttt
     2641 tagctttttc agctgcatct ttcaagcgtt gaagtgccat cttatcttgt gataagtcaa
     2701 taccattttc tttcttaaat tcagccacta agaaatcaat aattttttgg tcaaagtcgt
     2761 caccaccaag tttgttatca cctgctgttg caagaacgtc gaagacacca tcacctaatt
     2821 caaggattga tacgtcaaat gtaccaccac caaggtcaaa aactaagatt ttttcatcct
     2881 tgtcagtctt gtccatacca taagcaagtg cagctgctgt tggttcgtta acgatacgtt
     2941 ctacttcaag acctgcaatt ttaccagcgt ctttagttgc ttgacgttgt gcatcgttga
     3001 aataagctgg aacagtaata actgcttttt ctactttttc tccaagatag tcttcagcat
     3061 aacctttaag gtattgaaga atcattgctg aaatttcttg aggagtatat tctttaccat
     3121 ttgcagaaac tttttcagaa gttcccattt tagatttaat agagattact gtttctgggt
     3181 ttgtcactgc ttggcgtttt gcagcatcac ccacgataat ttcaccattt ttgaatgata
     3241 ctactgaagg agttgtacga ttgccttctg ggttagcaat gatttttgat tcagtccctt
     3301 caagaactgc tactgctgag tttgttgtac ctaagtcaat accaataatt ttagacatgt
     3361 taatacctct tattttataa tactttatta ctttttattt caatttatct tagtaagcac
     3421 tcgaattatt ttacttccaa ttctaagcaa tcactatagt ttaatcagca agcgaaatag
     3481 cttctaactt gctatctagt ttactgtcat tacggacaaa aacgaaaact catttacctt
     3541 agttataaac aactaccatc gctggtctta gcagacgctc gtgcaattta tatccttttt
     3601 gaaagacttc tgcaatgcta tcggctggat gttcatcatc ggctgggagg gtctgaactg
     3661 ccatatgaaa gttgtggtca aatgagtcga cttctacttc ttctacgcct tcttccttta
     3721 gtgcttgaat aaggctatca cgagtcattt ctaaaccttt tttaacatca tctgtcaacc
     3781 cttcaacagc caaggcacgt tctagattgt caagcgatgg taagattgct tttgccagat
     3841 cctgagaacg atagcgttga agttgttgac gttcttcact agagcgacgc tgtatattct
     3901 gcatttctgc atgagctcgc aagtatttat tttcaaactc atcagcacgt tcgtttgcaa
     3961 gttctaactc tgatttttca ggagtttctt caataacttc ctcaactgtc tcttcagttt
     4021 cagtggcttc cacttcttct tgtaaatcgt cttttttaat ttcttctgac actgagtgcc
     4081 tccttttaaa taacttattg aatactgcca ttatcagtgg acttcataat ggttagaatt
     4141 taggtatcga taataatcac ctaatttagc agccaatacc tttccaataa tgtttaccaa
     4201 actaacagac ctacgataat ccatatcaat aggaccaatc aaactcagga gtccaaaccc
     4261 acggtaagga atcaaaaatt tgtgagtcaa aactgacaca tctgcaagtg cggcttcttg
     4321 actatctgcc acttggacag aagccatctc accttctttc agactttgcc tcaaagaaat
     4381 tgctacttgc tgttcattat ccaaaaactg atacgttgat agatctgaat acgttaaaga
     4441 atttaccttg ccagcaacaa ataccgtttc caaaaacagc tctgaaaaaa cataatcaaa
     4501 tagttgtaaa acattatccg tagtcacaaa atacttttga acgatctgag gaatttctgt
     4561 cctcaactta taatgaatat ctatgacact actatccagc aagcgctcct ctacgatagc
     4621 tttaaatgct atcaagtcac gtgtcaaaaa gtttcttgga atagcaaact gcactgtcac
     4681 tggcttagat tcatctaaag tcatgactgc tagagcatca tggttgctaa gctgaacaac
     4741 atcaaaccct gttaaacgtt gacgagctgg ctccacatct aaaataacgg atgtatagcc
     4801 cgtcatctcc gataaaatgt gactagcttt ttgaagcatg tcttctaatt tgaatgcttc
     4861 aaaatcaaaa gcttttatga catgataaat atcttgctca tcaatactat ctagtctaag
     4921 ggagtgctct acaaaatact taaaaccagc tggacttggc atccgtccac tagaagtgtg
     4981 cgctttttcc aacaatccca acttctctag ttttgccata tcattacgaa tagtggcgct
     5041 actagaatca atcgttctct gtaaagcttt agaccctact ggttcatgag tttgtgtaaa
     5101 tagctcaacg attaaattca aaatatcatt ttgacgttgt gtaatcacaa accaaccact
     5161 ccctttcgtt tagcactcta tttagtagac tgctaattta taattctatt atactcttta
     5221 tgggagacat gtcaagaaaa aaactcaaaa aaattagcac tctttataaa agagtgctaa
     5281 tttcagtcat agtttgttaa atcgttactt tcaatgacct gaatcagtcg cctagcatag
     5341 gttttatcag tataatgcaa atacttttgt aaacttttag ctggtgcttt ataacctttt
     5401 tctgtagcaa gattacgata caaacgctta tcgacttctt tgccctgccg aagcattcgt
     5461 aaataatctc taattgcact agcgtcatct ttataaatag catatctcac gttttggttg
     5521 gtttgtttag gggactttag ggtaatggct gcttgtcctg gagttgcttt cttgctaaaa
     5581 agattatgat acttagacgc tagtaatgtt tttccatcat gggtttccaa aagaatttga
     5641 gcaatcaaaa tagatggtct aatgccataa tattttgcca atggtttaac ttctttaccc
     5701 atttttgtaa taaattgttt ttggctgtag ttcaccctta cttctttatc tgcactagct
     5761 atcctttggc tactcagtaa gggacaaaca atcagcaata aaaagcaagc tagaagcgtt
     5821 aaaaaatacg gaaactttag tcgttttctc atcgtttctc ctttaaagca gcaatgtact
     5881 cttccaacgt taggttgtgc tgagccatat aacgagcaga cgccttacct acatagcggt
     5941 aatgccaatc ctcataatca acccctgtac tagtcttttt tccttctgga aagcgcaaga
     6001 caaacccata atcaggtgca attttttgaa ctgctttagc taccgatggg tcactggcat
     6061 ttaaagtatc tacagtgctc atgtcaatag caagaccagt gtgatgttca ctagtccctg
     6121 gcggctgtga ataggtttgc accaaagcct ccgcagcttc ttgtgtcaat gttggatcgt
     6181 tagccatctc ttttttaata taagattggt aaagctctgt ttggtagtct acggaacggt
     6241 acccagagat aagatgttct tgcgagtcga tagcttgtgc tgctgctaaa aagtcactag
     6301 tggcttgctc aatgcgttta tccacagaaa taccattaat gtcagctaat tcaggactca
     6361 tttcttttgt aatgtgatcg cggtttacta aaaccagctc ccaatcttca acagatacct
     6421 taggtaaagc tcgtaaacgg tccgtttttt tgatatcttt ttgttggatt tcttttttat
     6481 tcaactgagt tggtgttact gactcttctg gttttataaa gaggtaaagc cctcctaaaa
     6541 aaacaataac aattagcaat tgcactaaat agtttaacga attatatttc atctgactgt
     6601 tcttctatta tttcacgacc gcggtagcgg taactcatat ctccaatagt ctttatcgta
     6661 aattggccat catcaaattc aacaactgta acgctcccat tatcaatata ctgtttgtct
     6721 cgatctggat caatcaacca cagaaacgtt ccaattgtca taccatggct aaccacaaga
     6781 gcatttccgc cgccagcatt ttgaatggac aaggcaatag cttcaaaccc ctcccaaatg
     6841 cgcttacgaa gaacttccca tggttctgcc caattagcgg tatctacttc cacgatgctt
     6901 tctgccagtt cagaataggg aacatcacgt aggttatcac gattttcaaa ggcttttgtt
     6961 cttggaagga cacctagaaa taattctgaa tcataagtcc cttctagact cccaaaacac
     7021 cactcacgaa tacgattatc tttagtataa ggcaaaaatt cgttttctga ttctcttaaa
     7081 ataatttcta ttgtctgcat ggttcgacct gaatcacttg aaaacgcagc cttaaatggt
     7141 atagttgcat cttttaaacc taagccaagt tctcgaatac cttcttctcc tttttttgta
     7201 agaggtgtgt cactccaacc ctgagcgcga ccaatggtat taaacatcgt ttttccatgt
     7261 ctggcaatat acaaccttgt ttttgtcatt tcaacctcct aaactgtctt attaattatt
     7321 atagcattta aagaaaacac ttgcaaaaca cttcctgatg gctatttgag atcaaataga
     7381 ccactgactt attgtctatt ttattaaaaa taatgctatt gctacaattc aaatcatcac
     7441 ataaatttcc aaacgattac atttgtgtgt ttcgctcaaa tatatataac aacagaccca
     7501 cactacaact aaactgacgt tacaaaatga tgtcaaaaca gtaacaaaat ctaactattt
     7561 gtcaagaaaa tgatattaaa ttttcacaca actgtcttat aatgaggatg caaccaataa
     7621 aaagataaga cattttatgt tgcaaaaaag gctgcttgga aacttccatg cagccttttt
     7681 tttaatacct ttttccaaaa atagctgaaa caagtacaat tacaattgct gctcccaaaa
     7741 tggacgggaa aatagccata cctgccaact gaattcccca atccccaaaa agcctttgcc
     7801 caacagctga ccctatgaga cctgcgataa tattagtaaa acaacccatg gactggcttt
     7861 tttcagtcat tttacctgct atcatgccga taaaggcacc tacaattaaa gaccatatca
     7921 tcattaacac ctcctttctt gtaaaatcct tttagaagaa ctgctatcca ttaaatgtgc
     7981 ttaactttag ttgattcctt taccttcttc tttagtaagt gtttccgtgc ctgagtaaaa
     8041 tagaaaaaac aattcattct attaagatag atcgagaacg actagaagtc ttcgcacact
     8101 aaataactta acaaacttta tcacacagct aatcgctaat aatagtgtag acaaacgtga
     8161 tggttcatta aatacccgtc agaaactcct gaaggttcta aagcaatacc tgtcagtctt
     8221 attttagcat agatgatggt ctttttatag gcggtcacta acatgacata caaaaaggca
     8281 gcctgtgaaa gaccgaccgc ctttttttca gagacaaaat actttaactt attgctatca
     8341 gcaactatca atctagcaat ttttgcaatt cttgtgccaa taattgttga gcgacttgtg
     8401 gattagcttg acctttggtt gccttcatca agaagcctgt gaaagcctta tcagcgttac
     8461 gtttacctga tttgaaatca gctactgcag cttcattatc agcaaagact tggtgaataa
     8521 ttggtaccaa aacagcggga tcagaaatct gaacaagtcc tgccttttcg acgtaggcgc
     8581 gagctgagcc accattttta gccaaatgca caaagacctt cttagccatt ttagaagaga
     8641 ttgtaccatc agcaatgata gcaatcatct ccaccaaatt ttctggtgtc agagcgattt
     8701 cttcaatggt tttgccttct gcatttaaga attgggcaac ttctccttgc aaccagttag
     8761 agacttgctt ggcatcgcca ccaagactta ctgcagtttc aaagaaatct gacaaggctt
     8821 tggtagctgt tagctggcta gcatcataag ctgagaggcc aagttcctct tcgtatttag
     8881 cacgacgttg agctgggaat tgaggtaatt gagcacgcat ctcgtcaatc caagcatcat
     8941 caatttcata taagggtagg tctggttctg ggaaataacg atagtccgct gccccttctt
     9001 tgacccgcat caaaatagtc cccttattcg cttcgtcata gcggcgcgtt tcttggcgta
     9061 tcaccccacc tgaacgcaag agtttggctt gacgttccac ctcaaattca agccctttac
     9121 ggacatttga gaaggagttc aagtttttca attcggtctt tgttccaaat tgttcttgcc
     9181 cgtaaggacg aagggaaata ttggcatcca cccgcataga gccttcttcc atcttgacgt
     9241 cagaaatacc cgtatactgg atgatttctt tcagagctgt caaataagca taggcttctt
     9301 caggagaacg catgtcggct tctgacacaa tctcaatcaa aggaactcct tggcggttaa
     9361 ggtctacata agaataacca tctgtgccgt gagtgttttt accagcatct tcttccaagt
     9421 gtgcgcgttc aatacgaatt ttcttggttg aaccgtcttc caatttaatc tcaatccatc
     9481 cgttgtagcc aatcggctcg tcaaactgtg aaatttgata agctttagga ttatctgggt
     9541 agaaataatt tttgcggtcg aaatgcatct ctttatggat gtccatattg agggcaagcg
     9601 cagcttttat gcccgcatca ataacgcctt tgttcatgac tggtaagacc cctggaaaag
     9661 accaatcaat cacattcgtg ttggcatttg ggtcctcacc aaagtgagct gacgaaggtg
     9721 agaaaatttt ggaattggta tttaattcca catggacttc aagcccaata atggtttcaa
     9781 aattcattac ttgtcacctc caaaaataat cggttgttgc ttgtgataat ctgtcaccgc
     9841 ttcaaaggct gctgccgctt gatagatggt ttcttcagcg tatttcggac caattaattg
     9901 aagccctact ggcaagccat cgacgaatcc tgccggaata gaaatacctg gcagaccagc
     9961 caagttaacc ggaatggtca ataagtcggc caaatacatg gcaacaggat cgtggttgag
    10021 tgtgtctaag ccaaaagcaa ccgtcggtgt tgttgggcct aaaataagat cataatccgc
    10081 aaagaccttg tcaaaatctt caataatcaa ggtacgcact tgaccggcct ttttgaaata
    10141 agcgtcataa taacctgatg acaaactaaa ggtcccaagc atgatacgac gtttaacctc
    10201 atcaccaaag ccttggctac gagtgttaac atagatttca tccaagtttt tagcatcgtc
    10261 agcacggaat ccataacgaa tgccatcaaa acgttgtaag tttgaggacg cttctgacga
    10321 agcaataatg taatagacag ccacaccata tttgctatgt ggaagactaa cttcctcaac
    10381 agtagctcct aaggcttcaa attgtttagc tgccgcaaga accgtttcct taatctcagg
    10441 atcaatccct tcgccaagat actctttagg aagggcaatc ttcatgcctt taatgtcacg
    10501 accaatctta gatgtgtagt ctgcaatgcg gacaggcgct gaagtggcat ccttgacatc
    10561 gctacttgca atcacattta ataattgggc gttttcttta actgtcggag caaaaggtcc
    10621 aatctgatca agtgaacttc caaaagcaat gagaccatag cgagaaacag tgccataggt
    10681 tggtttcaaa ccgacaacac cattaaatgc agctggctgc cgaatagaac caccagtgtc
    10741 tgaaccaaga gataaacgga cttgtcctga agcgactgct gttgccgaac cacctgatga
    10801 gccaccaggt acttttgtgt ggtcccaagc atttttcgtt ttcttgaaat aagaggtttc
    10861 tgttgaacca cccatggcaa attcatccat gttggttttt ccaatgacaa tcatgtcttt
    10921 agcgtaggca tttgctactg atgtggcatc aaaaatcggc tcgtagttat acaacatttt
    10981 tgaagcggct gtggttagga tgcccttggt tgagatatta tccttaacag ctagtggaat
    11041 acccgacatg aggttatcag catcaatacc tttggcatca attgccgcag cttgtttaag
    11101 agcagcttct tctgaaacag tgataaacga cccgacagcc tcctcacgag acttgatgtc
    11161 ttcaagtgtt ttttgagtca attcggttgc ggaaatctcc ttagctacaa ggaggtcatg
    11221 caactcttca atggttttat gattaaaaga cattaggcat ctcctccgtc atccaaaata
    11281 gcaggtacct tgataaagtg attttctttt tcaggaacat ttttaaagag caaggcacgg
    11341 tctgttcctt cttcagcgac atcttgacgc atcacatttt tcttatctgc catggttgtt
    11401 gtaatggcca caccttcggt atcaacttcg ttcagcaatt caaccatgtc aacgatttta
    11461 gatagggtcg ttgcaaaggt tgttgtctca ctttctgaga atgataattt tgatagcttc
    11521 gcgacatggc gaacttcttc ttcagaaatt ttcatgattt ctcccatcca agatgacaag
    11581 aagtattcca gttccaaaga acagctctgc tattctctaa aggtagcgga aaaacttctc
    11641 acatcatttt tacatagtct caattattat atcacaattg ttcccattta ccataggtga
    11701 ctaatgcaat tctagaaagc catccagcaa aaaacttcct gactaaggtc agaaaacctt
    11761 agtcaggaag tgtgacaaac taaactctat ttgtcttggg taagactgtg gcctgaagct
    11821 ttgatggcag cctgagcagc cgccaagcga gtaagcggca ctctaaatgg cgaacaagaa
    11881 acgtaggtca ggccttggct gtggcaaaag gcaatggaag caggatcgcc accatgttcc
    11941 ccgcaaatgc caagtttcaa cttagactta accgaacgac ctaatgaaac agcggtacta
    12001 aagagacggc caatcccttt ctgatcaaag gtctggaacg gctccttatc aaaaataccc
    12061 ctgtcaacgt attcttccaa gtattttcct acaacatcac agaaaaagta acggtctttc
    12121 aagtcggtaa tatgtttacg aaggtaataa aggggtgctt tattctaatt taccaaatcc
    12181 tcaacgattg tgacaacatg tgatgtgata agcctaagat aaaaatggta cagactctag
    12241 cattcaagag tttgaagctt tatttatatt ctaatgctga aaagactaga gtttgtctaa
    12301 tggctgtgag acgatccttt aaaccatcaa ctcaaatcat ttctcaaaca gctaaaatcc
    12361 tgtcttcttc aaaaaaacat gtgttctatc tgacacagtc caaagtttag ttgcctttta
    12421 gacagcacaa gaatcatcag gactaattct gaccagcatg tcacatacct catctaccta
    12481 acccatacat acggtaaaac cacatagagc aatgattacg gttcccaaac tcttagtcac
    12541 tgaatcaata gtttggtagg ctcttttagt aatcgttaat aagcttagca ccaagaacct
    12601 gctcaaagtg agccaaagac cactcataag attcttttgt aaggctagcg acagctgatt
    12661 taacaatctc taattgataa ccaagatgat aagcgtcaat agcagtatgt aagacacaga
    12721 tatcagataa aactcctgtt aacactaatt gagtgatacc tctttctcgt agtctaatat
    12781 ctaaatcagt ccccgaaaaa gctgaataat aacgcttatc aatccaaaaa actctgggat
    12841 gttgcttcat atgactgtaa acttcagcta gtggaccata aagatggcgt ccagtagttc
    12901 ctttgatatt atgtgctgca aatagcttac tctcaggatg ccaaggatca ttttgatcat
    12961 gacaatcaat agcaaaaaaa atatagtctc cttgatcaaa tgccgtttta gttacctctg
    13021 ctattttagt ggcaatagcc tgagcagatt tacctgcact taatttacca tcatctgcta
    13081 caaaatcatt tgtgtaatca attgaaatca atgctctcat cactatctcc taaacaggga
    13141 aacctctccc cttatctctt atatatggca ttgtatcagt ttttattaca ggtatcaaga
    13201 catctatttg catctaccat taacagcaaa aaacatctct tttcaagaga tgttgtcttt
    13261 ttctatttaa aattctttta atttagcaaa aataccttcg ttgataactt tgaggtatgt
    13321 ccctttcata ccaagagaac gactttcaat aatccctgca ctttctagtt tacgcagagc
    13381 attgacaata acagaacggg taataccaat acgatcagca ataacagaag ctgtcaatcg
    13441 tccttcgtta ccatctaact ctccaagaat tgctgcaaca gctttcattt ctgaataaga
    13501 aagcgtatta attgccatgt tgaccgctgt ttgtttacgg atggtgtctt ctaagttttc
    13561 tgtctgaaga tttaatagtt gaatccccac aacagtactt gagatctcaa ccaaaatcaa
    13621 atcatcatca ctaaactcat tgtcattacg ccagataatg agtgatccaa ggcgcatccc
    13681 tccaccataa atcggcgcaa tagtcgttag acctcctgga taagtgtctt tagactcaac
    13741 agggaatata gtcaattcat tttcgacaga aaggttagct tctgtatcgt aaactcggct
    13801 agcagccttt acataagtat ctggaaattg tttagcttca aaaaattcct caacacgatc
    13861 agtgttagtt ttatatttca tggcataacc aagcaatgtg ccgccgccat tgataataca
    13921 agcattgcag tcaatgatat ctgctaggcg agatgccatt gtgttatacg gtaattctgt
    13981 ttctaggcta tctacggaac gctgcaaaat agatgtgatt ttacgagttt tttctaataa
    14041 gttaggcatt tttttccttt tcctttgaat tatttgcgct ttcattataa caaagctaac
    14101 tcgcttttgc aaggaattat cagaaaattt tctattctta ctacaattcc aactattaat
    14161 gccttattat cacttcattt aaaggagata agcactagct tgttagagca tagggtcaca
    14221 ttcttttaag aaacgctatt tttattaatc aaagatgagc attgcattaa cgtctatact
    14281 ggtataagac acgtgtaatc ttttcttgga catcttctaa ttcttctaca cttggtaggt
    14341 aaacaatacg gaagtgatct ggatctttcc agttaaaacc acgtccatgt accaacatca
    14401 ctttttcttg ctttaataac tgtaagacaa attcttcatc atcatcaata cgatacatct
    14461 gacgatcaat tttcggaaat aaataaagac ctgcttcagg tttaactgcc gataagccag
    14521 ggatagcatt aatagcttca taaataaaat tacgttgctc aaaaatacgc cctcctggca
    14581 gtaacagtgc atcaactgat tgatggcctc ctaaggaagt ttgaacaact tgttgggcta
    14641 aaacattgga gcataaccgc atattggcaa gcatgttcaa cccttcaata taacctttaa
    14701 catggtcttt aggacctgat aagaccatcc atccaacacg aaaaccagca atacgatgag
    14761 atttggaaag gccattcata gatacacaaa aaacatcagg tgccaaactt gcaatagcaa
    14821 tatgctcttt accatccatc accaaacgat catagatttc atcggcaaaa ataatcagct
    14881 ggtgttctct tgccaaagca acgatgtctt ctaaaatctc cttaggataa agggctcctg
    14941 ttgggttatt aggattgatg accacaatag ctttggtgcg actcgtgatt tttgatttga
    15001 tatcagcaat atcaggatac caaccagctt cttcatcaca aagataatgg actgcttttc
    15061 ctccaccaag actcacacaa gccgtccata aaggataatc cggcattggt actaaaactt
    15121 catcgccatt atctagcaaa gcttgaaggg acatggatat caactctgac acgccatttc
    15181 ccaaataaat atcttcaatg tcaacatctg ggaagccctt gagttggcaa tactgcatga
    15241 tagccttacg cgctgaaaaa atccctttac tgtcagaata gccctcactt agcctcgcgt
    15301 tgacaattaa atcacgaatc acttcatctg gtgcttcaaa accaaaggca gcaggattgc
    15361 cagtatttaa acgcagaatt ttttcaccac tcgcaatcat gcgattagct tcatccaaaa
    15421 caggccctcg aatatcatag gcaacatgtt ctaattttga tgatttttca ataattttca
    15481 tagtctcata cacctcgtat tccatattat aaaccaaaat acttaaaata gaaagaattt
    15541 atccatcaaa gcttaggaca gctaatcgtt ttaacacagg tcttatgaga cgataataca
    15601 gtctttagtt tagctaaaat aatggatcgc tttcaaaatg actcaaaaaa gagtataatg
    15661 aaaaaaagaa taaaagctat tcttgtcaaa ctgttaaagg aggacagttc tatgtcacta
    15721 aaatataaac gtatcctcgt tgctattgat ggctcttatg agtctgaatt agctttcaat
    15781 aaaggcgtta acgtagcact acgtaacgac gctaccttac tactagtaca cgttattgac
    15841 acccgtgcct tgcaaagcgt agctactttt gatacttaca tctatgaaaa attagaacaa
    15901 gaagctaagg acgttttaga tgattttgaa aaacaagcac agatagcagg aattacaaac
    15961 atcaaacaaa ttattgaatt tggcaatccc aaaaacttac tagctcacga tattccagat
    16021 cgtgagaacg ctgatttaat tatggtagga gctactggtc ttaatacctt tgaacgcctc
    16081 cttattggct catcttctga gtacattatg cgacacgcta agattgactt acttgtagtc
    16141 cgagatagca ctaaaacact ctagtctatt acaattttca aacaccaaaa aacaagcagc
    16201 atctacaacg aaattgcttg tttttttgtg ctgagctaag gctagtcaat atctttttat
    16261 ttcttgatat ttaaaagagt aaacctctat ttatcgaatc gttgtagtga tttttgtaat
    16321 tgtttgtcta actctttttt tatggctact tcaggtgcgt gacgctcttg ccaatagtca
    16381 ggtttttgaa ttttatgggt aacggggtca aagtgtgcct tgccatctgg aaaaatttta
    16441 gccatatttg cttcatgtac tgcttcaaat ataggttgtg gatctactcc catcagtaca
    16501 aaagaaccat aagtaaaata aagcaaatcc gctaaggcat caacttgccc aatcaggggc
    16561 gtttcaacat gttttttagc ttgtacctta ttagctgctt ggtcaacagc accatgcaaa
    16621 tcgaaaatag cctgtgtaaa ttgttgttgg tctcccttgc ttgctgcgta aagaaactca
    16681 acaatttctt ctactttgaa gcctgaccta taaccagctt ctgaaatggt ataactacgc
    16741 ggtgtttcaa tagtatctga gtccatcaga cgatgaaaat ctttgacttt attaaaattt
    16801 tcatcacggc ttttaaagct cttctctaca tcaaaatgga tgagaccgta gtgagctaag
    16861 gctttggaaa tcccatcatt attattagag tcggtagtga aatgggctcc atcttttacc
    16921 acagtttcag catttcccat agcaacaccg ataccaactc ctgataacat ttcaaggtca
    16981 ttatctgaat ctccaaaagc catcacttca gacaagtcaa atccaaacat ctctcccaaa
    17041 cgttcaattc cttttatttt tgattgatca acagagatca gatccaagga ataaggacta
    17101 cttcttgtaa tttttatatg agggaacttc tcttgtattt tcttagtttc agcttgtgac
    17161 gctaccagaa caacctgata aataggctcc cgcataatag ttactaaatt tctaaaactc
    17221 tgtggcttga ttcggcgaat caaatgctta aaactaccct caactgttct tgcccaactt
    17281 ttgggcacaa aactactaat gacttgtcca aatgggctag tccccatatc aataatacgt
    17341 gatcctgcta atccagaagc tgttccaaga gaaatttctc gctttttttc gttggcatag
    17401 cgaatcactt tgtaaatcat cgactttggc aattgattct gatataagac cttatctctt
    17461 gttaagatat attggccatt gtaagtaacg gcaaaatcta atccaaaatt ttctagaaaa
    17521 ggttgcacaa atcccggtcc acgaccagtt gctaaaccga ccataatgcc ttgttttttg
    17581 agttgttgga tggctttttg cgttgttttt tggatatttt tacgatcatt gagaagggtc
    17641 ccatcaatat caaaaaagac tgcttttact gtcaaaatct tcttttgcct cctgtgttta
    17701 tgatagaata gattatacca taaataaaag gaagtttgac aatcaaatga aaaaaatcct
    17761 agtcttacac actggtggaa ccatttctat gcaagctgat aactctggta gggttgttcc
    17821 aaatcaagat aatcctatga cgaaaataca tgctgcagcc caaaatattc agcttaccgt
    17881 tagtgatttt ctaaatcttc cgagtcctca catcacgcct caccacatgt tatctattta
    17941 tcatcatatt caagaaagaa ctgatgtttt tgatggtata gtcatcacac atggaacaga
    18001 taccttagaa gaaactgctt attttttaga taccatggca ttgcctacta atatacctgt
    18061 tgtcctaaca ggtgctatga ggtcttctaa tgaagttggt agtgatggca tatataatta
    18121 ccttaccgca cttagagttg caagtagtga taaagctaaa gaaaaagggg tacttgttgt
    18181 tatgaacgat gaaatccatg ctgctaaata tgttactaaa acacatacaa ccaatatttc
    18241 aactttccaa acacccacac acggaccgct tggtatcatc atgaaaaatg acctactttt
    18301 tttcaaaact gctgaacctc gtattcgttt tgacttgaga tgcatttctg gaaccatccc
    18361 cattatcaaa gcatacgcag gtatgggcga tggtagtatc ttgagcctat taactccagg
    18421 tagcattcaa ggtctagtta tcgaagctct aggggcagga aatgtcccac cattagcagt
    18481 tggggagatc gagcacttaa ttactttagg tattcctgtc gttcttgttt cccgttgttt
    18541 caatggtatg gcagaacctg tctatgctta tgaaggtggt ggtgcgatgc tacaagaagc
    18601 aggtgttatg tttgtaaaag aattgaatgc tccaaaagcc cgtctaaagt tattaattgc
    18661 tctcaacgcc ggacttactg gtcaagagct aaaagattat attgaaggat aatctacctt
    18721 cctgtagaaa tgtcccacta aaacatatta gtgggacatt tctagtactt taagctttaa
    18781 attaggacat ctcctaaatg tctataataa acaactatgt ttcaaactat gagattgtgc
    18841 actcataatc atttctataa cagtttgaga ccagtattcc aataaatcca actcttagca
    18901 atcagatacc gggtaaacaa gtctttattt tgtctcatta agtatgagct tgcttgaata
    18961 ataacaaaac tacttgctca tcctttttta gtaatgatga agacgacctt tttctaagaa
    19021 cttctttgtc ttttaaaata aacaaggcac atattaccct ttattttagt tctcgtttgg
    19081 aaaaaagaaa gacattgcct aaaagataac aaagagttaa accaaaggcc actaatatgc
    19141 tagtactaga aaggtgttta tcaccaagag acaaggatag gtgtttaaac atcaaaactg
    19201 ggctaatatc taacttaaaa aaatggtttg ctaaagtagc agatacttta tcaaaaagaa
    19261 ggacataaag tatataagct gtgattgact gataagtttt acgaagtata ttaaacaaaa
    19321 attgacacaa agcaataata gcaatataaa aaggcagttg tttaatcatc cgatctatga
    19381 ctattccata gtatgcttga ccagtaaata aatgaaatgc taaagcacta agaagataag
    19441 ttaaactaat aaataaaaga gataagccaa aactaactag cagtttatag attataatta
    19501 aagtacgatt ttgttgtttg accacaacat tattaatcgt acggtagtta tagtcatcac
    19561 taaaaaagat acgggctggt gttaaaaaga aaagcgtcac aaaatcagta ataatattaa
    19621 tgatttgtat catgatgact tggttaggtg tcttgcgaaa actataggct acaccaacag
    19681 caatgacaac aagtagcata caagaaaata gagctaaacg ctcttgacgt atccgaaata
    19741 aatctgcttt aagataggaa atcataaaaa cctctttcta aattaatggt gatgctgcat
    19801 ctttacctaa caaatcgagg taataatgtt caaagctcac ttgatgatga taaatgtcaa
    19861 aaatctcaac aggcagatct agaacaattt tgataagctc cattactgat aaagttggtt
    19921 ttattagtag catctgacca tcagtctcaa ctctaagccc caattctaaa agtctatttt
    19981 ttaccagctg atcatcgctt gtatgaaggg caatttgtac ttttacttga gctttaagct
    20041 ctgctttgtc catactctta ataactttgc ctttatgcat aatcacgtaa cgatcaacaa
    20101 ctaagtctaa ttctgataaa atatgactgg aaatcaaaat cgtaatacca tagcaatctc
    20161 ttaggttcaa aataatctga cgcatttctt tgattcctgc tggatcaaga ccattaatgg
    20221 gttcatctaa gattaaaaat tctggaaaat ctagtatcga aagaccaata gccaaacgtt
    20281 ggcgcatccc caaagaataa tctttcacct ttttcttttt gctcactttt tctaacccaa
    20341 taagttccaa aacctcatgt atgcgctctt ttgcatcagc taatctcaat tgcaacgctg
    20401 catagtaaag attatcatga gctgtcatat tgggataaag tgtcggtgac tcaataattg
    20461 atcccattcg atagggttgt aactgtttga tttgccctga atcttttcca attaggccag
    20521 ataaaatacg cattaacgtt gtctttccag caccattttg acccacaagg ccgcaaattt
    20581 ctcctttgta aatatcaaaa gagatatcac ttaaaacctg atttttacca taggatttat
    20641 ttacttgttc aatacttagt aacattgatt gctgtgtcat tttccgctcc ttt
//
LOCUS       DAUGSW010000025        20112 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUGSW010000025 DAUGSW010000000
VERSION     DAUGSW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20112
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.025"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            268..642
                     /locus_tag="VIB18_001160"
     CDS             268..642
                     /locus_tag="VIB18_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766171.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEESLGQAKEKVEGIGEATSQ
                     TIQSKMEKLTSDKTDADDDDEK"
     gene            complement(692..1603)
                     /locus_tag="VIB18_001161"
     CDS             complement(692..1603)
                     /locus_tag="VIB18_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8766172.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(1720..2370)
                     /locus_tag="VIB18_001162"
     CDS             complement(1720..2370)
                     /locus_tag="VIB18_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEQ8766173.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(2367..2807)
                     /locus_tag="VIB18_001163"
     CDS             complement(2367..2807)
                     /locus_tag="VIB18_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEQ8766174.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLSQEVTQ"
     gene            3026..3874
                     /gene="ylqF"
                     /locus_tag="VIB18_001164"
     CDS             3026..3874
                     /gene="ylqF"
                     /locus_tag="VIB18_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEQ8766175.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNRPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFREYY
                     PNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDAD"
     gene            3864..4655
                     /locus_tag="VIB18_001165"
     CDS             3864..4655
                     /locus_tag="VIB18_001165"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEQ8766176.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKA
                     IQAELAEEERLEAMLSYEKALYKKGYQAIAGIDEVGRGPLAGPVVAACVILPQHCKIK
                     GLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     SQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            4720..5556
                     /gene="dprA"
                     /locus_tag="VIB18_001166"
     CDS             4720..5556
                     /gene="dprA"
                     /locus_tag="VIB18_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEQ8766177.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            5663..7792
                     /gene="topA"
                     /locus_tag="VIB18_001167"
     CDS             5663..7792
                     /gene="topA"
                     /locus_tag="VIB18_001167"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEQ8766178.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSINFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMEEGENVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(7867..8751)
                     /locus_tag="VIB18_001168"
                     /pseudo
     CDS             complement(7867..8751)
                     /locus_tag="VIB18_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            8764..9330
                     /locus_tag="VIB18_001169"
                     /pseudo
     CDS             8764..9330
                     /locus_tag="VIB18_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
     gene            9345..10337
                     /locus_tag="VIB18_001170"
     CDS             9345..10337
                     /locus_tag="VIB18_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEQ8766179.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESSLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWRLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNA
                     DLFKSFKKGAILMNMARGALIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            10442..11107
                     /locus_tag="VIB18_001171"
     CDS             10442..11107
                     /locus_tag="VIB18_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEQ8766180.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            11100..11816
                     /locus_tag="VIB18_001172"
     CDS             11100..11816
                     /locus_tag="VIB18_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEQ8766181.1"
                     /translation="MINGVSHYLAQPPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILVITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGLCMIMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            11973..13319
                     /gene="trmFO"
                     /locus_tag="VIB18_001173"
     CDS             11973..13319
                     /gene="trmFO"
                     /locus_tag="VIB18_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEQ8766182.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIDVIRDEITEIPDDAITVIATGPLTSDALAEKIHAVNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            13472..14878
                     /locus_tag="VIB18_001174"
     CDS             13472..14878
                     /locus_tag="VIB18_001174"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEQ8766183.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQARQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLV
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            14921..15235
                     /locus_tag="VIB18_001175"
     CDS             14921..15235
                     /locus_tag="VIB18_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766184.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            15235..15585
                     /locus_tag="VIB18_001176"
     CDS             15235..15585
                     /locus_tag="VIB18_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ8766185.1"
                     /translation="MKRYEVTVNGQVYEVSLRELADGETVEVSQPAAPATEKEMNANS
                     AGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            15595..16725
                     /locus_tag="VIB18_001177"
     CDS             15595..16725
                     /locus_tag="VIB18_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8766186.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDNPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(16926..17810)
                     /gene="citG"
                     /locus_tag="VIB18_001178"
     CDS             complement(16926..17810)
                     /gene="citG"
                     /locus_tag="VIB18_001178"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEQ8766187.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFI
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTTHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(17803..18498)
                     /locus_tag="VIB18_001179"
     CDS             complement(17803..18498)
                     /locus_tag="VIB18_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8766188.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(18656..20059)
                     /locus_tag="VIB18_001180"
     CDS             complement(18656..20059)
                     /locus_tag="VIB18_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEQ8766189.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
BASE COUNT         6353 a         3740 c         4063 g         5956 t
ORIGIN      
        1 ctttgacaac catttattgg tccttttaga taagacaatt ttgtggctct tcagttgaaa
       61 ggatgtgttg ttgatgttag aggaaacaat catgttaaat taactcaggc ttaaagacca
      121 aaaaaggagt gaagtctatt atgaaaaaaa gaaattttaa acttacagaa atgttacaat
      181 tggttttatt agtggttcct gctgtaaaac ttgctaaaaa aatttttaac gatagtaaaa
      241 caccgtctaa aagaaagtag gtctacaatg actaaaaaaa atcatggcgt tttttggggg
      301 ttgttgcttg gatcagcagc agctagcatt gcttacttaa gtttatcgtc ttccaaaaaa
      361 gatcaactct tgaaagatag tgctaaaaaa atagatgatc tcaacgctta cttgcaagat
      421 aaaagtaagc aagttctgga tgcagtatcg gaaaaagtac aagaatccaa agatgctgtt
      481 gaagtttatg gtggtattgc cgcagaaaca gttgaagaat ctttgggaca ggctaaagaa
      541 aaggtagaag gaattggcga agctactagt caaactatcc aatctaaaat ggaaaaactc
      601 accagcgata agacagatgc tgatgatgat gatgaaaaat aggttttaaa atacctttaa
      661 gataagacaa aaagtgccat taggcacttt tttaatcttc tgttggaaca ataatcgaaa
      721 tggcttttgg aatgatatct aattgaatgg gcagatagtc acttttatcc ccatcaatcc
      781 tggtacgtgg taatatcgct tgttttttag cttgtggtag taagctaagc gtattggctt
      841 gaaaatgact gatttcctct gctttggaaa aatcaccctg tttaaaatca ttaatatgcc
      901 ataaaaattt aaagaaagag acttttttca tggtataaac ttggaaatag ccatcgtcag
      961 cttgagcacc aggagaaaaa gaaggaaaac cagcaatggt atttgtcatc gtgattaaga
     1021 gaaacttcgt ttttaggtga atacgatggt tgtggctaat taaagagatg gcatagctgc
     1081 gatttctttt cagtattcga atactatctt ttaaaaatgc tagaggacca aagcgtcgtt
     1141 tttcctcagc cgttacgtcg gcagcaatat cagccagtaa tcctaaggtt aaactggaaa
     1201 tcatgtattg ctggttagct ttgcaaatat caacttgttt gatttgtccc gtcaagatag
     1261 tatccaacgc ctcagtaatt tgtaaaggga tatgcatagc cttggcaaaa ttattgactg
     1321 tccctgaggg cactaagcct attaaacaat gagctcctcc ttcatagatg ccaccgatga
     1381 ttttatttag tgtcccatcg ccaccaagag ggataaccaa gtcaatcttg tccttagcag
     1441 cttgttttgc taattgaaaa gcctggtcag catctttagg ggtaataact tctacagaat
     1501 cttcggaaaa accatgttgg caaaaatagt ctttgacttg cccagcaagt tggtcttctt
     1561 tctttccaga attaggattg taaaaaatcc gaacggtttt catcaggtct ctcctttgac
     1621 agcttattac ttgctatcca ttataccact tctaagaatt gatgtcttac accaactcat
     1681 cacattaagc ctctcaatca gtctgagcat ctatttatct taaagcataa agaaagtgat
     1741 agcgataaat tggagggcag aggccaataa aataaagaga tgccaaatca tgtggaagta
     1801 gggtcttttt ttggcataaa ataccgctcc aatggtataa gacaagccac caaataacat
     1861 gagaagacca aaagcaagac tagttttttg aatgatgact ggcaagataa acacaacgag
     1921 ccagcccata acgatataaa gcatcaaact gaatttttca ttgatacgtt tggcaaaaat
     1981 tttgtataaa atcccaaaaa gcgtaatgcc ccactgcaaa acaataatga tatagcctag
     2041 ccaaccagaa acaagggata aggcaacagg tgtataactt cctgcgatag caatgtaaat
     2101 catactgtga tcaataatgc gtagaatgta tttgtgaacc gaaccataag ccatggagtg
     2161 gtaaatcgta gaggataaaa acatcaaaaa gagactgatg acaaagatgg agataccaat
     2221 agcggcttta aggtcataag tttgataagc atagctggct gaaataggaa gtagaatgag
     2281 catagcaaat gctccgatag cgtgtgtcac gctgtttgct acttcctcac taaaagataa
     2341 gggtaaactt tgtttaaagg tttggttcat tgggtcacct cctgtgataa ataaatagtt
     2401 ttgtggtaat ctttgaccgt ttgacaggca acctgcacaa tcggtggaat gtcctcctca
     2461 atgggagcct tctgattcca acaggttaca aaagtattgt aaagactttc agaatcagcc
     2521 tgtgcctgaa gttcctccaa tacgcgacta atatcttgaa taggaaatac cgttttaaac
     2581 aaactgatgg caattaagcg cgctagttgt tgcttttggt attttttctt gataggttta
     2641 gtcacatacc catgcttgac gtaattatta atcatagatg ccgttagtga tttattatct
     2701 gacacttctg aaaaatcagt gcactggttg acataaagta agacttgatc caaatataag
     2761 tctaaatcag ggaggtcctt ccaataaggt aatgatggaa aaatcatagt ttcgtctctc
     2821 tatctagttt ttataactag attatatgat taatgaaaac ttattgcaag caaaaactgt
     2881 aaagacttaa aagaggaaag tagaaatggc gaagtgaagc taatcatgct ataatgttaa
     2941 agaattgatt gggatagatg ccttctgtcg caatcagact attttatcac gaagaagatg
     3001 atgctacgaa aggaatgata cactcatggc aatgattcaa tggtttcctg ggcacatgtc
     3061 caaagccaga agacaggttc aggaaaatgt aaagcatgtt gactttgtaa ctattttagt
     3121 ggatgcacgc ttaccacttt ctagtcaaaa tcccatgctt acaaaaattg ttggtgataa
     3181 acctaaatta atgattttaa ataaagctga cttggccgat gccactcgta cgaaagagtg
     3241 gaaggcttat tatgaaagtc aaggtattaa aacattagcc atcaattcta aagaacaatc
     3301 aacggttaaa aaagtaacag aagcagccaa ggaactcatg gctgataaaa ttcaacgctt
     3361 gcgagagcgc ggcattcaaa aagaaacctt gcgaaccatg attattggca ttccaaatgc
     3421 tggtaaatct accttgatga atcgcttggc tggtaagaaa attgctgtgg ttggcaatag
     3481 acctggtgtg actaaaggac aacaatggtt gaagtccaat aaggaattgg aaattctaga
     3541 cactcctggt attttatggc caaaatttga ggacgaattg gtgggcttaa aattagcttt
     3601 aacaggtgct atcaaggacc aattactacc aatggatgaa gtgactatct ttggcttgaa
     3661 ttactttagg gaatactacc ctaatcgttt aaccaaacgt tttaagaata ttcctcttga
     3721 ggaagaagct cctgaaatca ttatgacctt gacacgccaa cttggattta aagacgatta
     3781 tgaccgtttt tacactttat tcgttaagga agttcgtgat ggtaaattag gtcaatacac
     3841 cttagatcag gtgggagata tggatgccga ctagtattaa agctattaaa gaaagcttag
     3901 aggccgttac tagcctcttg gaccccctct ttcaagaatt ggcaaccgac actaggtcag
     3961 gcgtccaaaa agctctaaaa agccgacaaa aggctattca ggccgagtta gcagaagaag
     4021 aacgattaga agccatgctt tcttatgaaa aagctcttta taaaaaaggt tatcaagcca
     4081 ttgcaggtat tgatgaagtg ggacgtggtc ccttagcagg tcccgttgtc gcagcatgtg
     4141 tcatcttacc tcaacattgc aaaattaaag gtctgaatga ttctaaaaaa atccctaaat
     4201 ctaagcatga gaccatttat caggcagtga aagaaaaggc tttggctatc ggtatcggta
     4261 ttattgacaa tcagcttatt gatgaggtca atatttatga agcaaccaaa ctagctatgc
     4321 tagaagccat taaacagtta gagagccaac tcacacagcc agattatctc ttgattgatg
     4381 ccatgacatt ggatattgct atttcgcagc agtctattct taaaggcgat gccaattcct
     4441 tgtctattgc agcagcatca attgtagcta aggtcaccag agatcagatg atggctaact
     4501 atgatcgcat ttttcctggt tatggcttcg ctaaaaatgc aggctatggc accaaagaac
     4561 atttacaggg attaaaagct tacggcataa cgcctatcca tcgtaaaagt tttgaacctg
     4621 ttaaatccat gtgctgcgat tcaactaatc cttaaaaagt tctgttttta gcagaatttt
     4681 tttctttttt acgaataaat gaagtaagga ggtaacttag tgaatcattt tgaactttat
     4741 aagctaaaga aagctggact gactaataaa aacattctca atattcttga ctaccaagaa
     4801 caccaggaaa aatcgttgtc acttcgagat atggccgttg tttctggttg taagcatccg
     4861 tctcacttta tagaagccta taagcagtta gatattcaaa atttaaaaat agaatttaaa
     4921 cagtttccta gtatttctat cttagataag cattacccaa tggcattgaa agaaatatac
     4981 aatccacctg tcctcttgtt ttttcaggga aatttagacc ttcttgagaa acctaaatta
     5041 gccattgtcg gctccagacg ctcaagcgat accggagtaa agtctgtccg taaaattctt
     5101 aaagaactcg ggaaccgttt tgtgattgtt agcggacttg ctcgaggtat cgacactagt
     5161 gctcatttag cctgccttaa aaatggggga caaaccatcg ctattattgg aacagggttg
     5221 gatcgctttt accctaaaga aaatagggag ttgcaaactt tcttagggaa aaatcatctt
     5281 gtgctaacag aatacggtcc aggagaagaa gctttatctt atcactttcc agaacggaat
     5341 cgtattatcg caggccttag ccgaggtatt cttgtcgttg aagcaaaaaa tcgttcaggt
     5401 tccttgatta cttgtcaaat tgggatagaa gaaggccgag acatttttgc tgtcccagga
     5461 aacattttgg acgggaaatc cgaaggttgc cttcagttaa ttaaagaggg agcaacatgc
     5521 gtcacgtcgg gcatggatat cctttcagag tactaaaaaa gttaaagttt cttcctatgt
     5581 agcatttttt tattgacagt ttcttaaaaa tgggatatta tgctataagc tttaaacaaa
     5641 ctgttatagg aagtgtgtcg aattgggaac aaaaactaca actaagccaa aaacgggtac
     5701 taaaaagtcc accactaaaa agaaatcaac agcgaaaaaa aatctcgtta ttgttgaatc
     5761 acctgccaaa gctaagacta ttgaaaaata tcttggacgc agttataaag ttgttgcttc
     5821 ggtaggacat attcgtgact taaaaaaatc gtctatgtct attaattttg ataataatta
     5881 tgagccacaa tacattaata tccgtggtaa gggacccctt atcaattctt taaaaaaaga
     5941 agccaaagct gctaaaaaag tttatttagc tagtgacccg gatcgtgagg gagaggctat
     6001 ttcttggcat ttgtcacata tcttaggact tgatcctcaa gataataacc gagtggtttt
     6061 taatgaaatt acgaaagatg cagttaaaca tgcctttgtg gagcctcgtc agattgatat
     6121 ggacttggta gattctcaac aagcacgtcg tgttttggac cgtattgtgg gatattccat
     6181 ttcaccaatt ctttggaaaa aggtcaaaaa aggactttca gcaggacgtg tccagtcggt
     6241 tgctttaaaa ctcatcattg accgtgaaaa tgacatcaaa gcatttgttc caaaggaata
     6301 ctggtctatt gatggtcttt ttaaaaaagg aactaaaaag tttcaagcga ctttttacgg
     6361 tattaatggc aaaaaaacaa agcttgataa taacaacgat gtcaaagagg tattagcaaa
     6421 gctaacaaat gaagattttc ttgtcagcaa ggttgacaag aaagagcgac gtcgtaatgc
     6481 tcccttacct tacacaacat catctcttca acaagatgct gctaataaaa tcaatttcag
     6541 aacgcgtaaa accatgatgg tagcccaaca actgtatgag gggattcatt taggagaaaa
     6601 tggaactcaa ggtttaatta cctatatgcg tactgattct actcgtatca gtccagtagc
     6661 acaaaacgat gctgctcaat ttattatcaa tcgctttgga gctaattatt caaaacatgg
     6721 taatcgtgtc aaaaatacca gtggtgccca agatgctcac gaggcgattc gtccatctag
     6781 tgttaatcat acgccagact ctattgccaa atacctcaac aaggatcagt taaaacttta
     6841 tacgcttatt tggaatcgtt ttgtggctag ccaaatgaca gcagctgttt ttgataccgt
     6901 aaaggtgaac ttggagcaaa atggcgtgat ttttgttgcc aatggaagcc aaatgaaatt
     6961 tgacggttat atggctgttt ataatgactc agataaaaac aaaatgttac ctgaaatgga
     7021 agaaggagaa aacgttaaaa aggtatcaac ttctccagaa cagcacttca cgcaacctcc
     7081 ggctcgctac tccgaagcaa ctctgattaa aactttagaa gaaaatgggg tcggtcgacc
     7141 atcaacttat gccccaacct tagaagtgat tcaacgcagg tactatgtta aattatctgc
     7201 taagcgcttt gagccaactg agcttgggga aattgtcaac aagcttattg tcgaattttt
     7261 cccagatatt gttgatgttg cctttactgc cgagatggaa ggtaagctag atcaagttga
     7321 aatcggtgaa gaagaatggc aacatgtcat cgatcaattc tatcaaccct ttgtcaaaga
     7381 attgaataag gctgagtctg aaattgaaaa gattcaaatc aaagatgagc cagctggttt
     7441 tgactgtgat gtttgtggcc acccaatggt cattaagtta ggacgttttg ggaaatttta
     7501 cgcgtgtagc aacttcccag agtgccgtaa tacaaaagcc atcactaaag aaattggtgt
     7561 tacttgtccg gtttgtcata aaggacaagt tatcgagcgt aaaaccaaaa aaaataggat
     7621 attttatggt tgtgatcagt atccagattg tgagtttatc tcgtgggatt tacctattgg
     7681 acgtgcttgc cctaagtcag gtgactatct tattgagaaa aaagttcgtg gtggcaaaca
     7741 agtaatgtgt agcaatgaga cctgtgatta caaggaagaa aaaattaaat aaaaaaagaa
     7801 ttggaactcc ttgtcttgtt ccaattcttt ttttatttac aaaggtattt ttaactacaa
     7861 aaatcgctag ttcgttttta aaaggcttaa aaattcctca ataactggac tgaaactcgc
     7921 atcatctcgg taagcaatcc caatagggta aaaattattt ttatcttgca aaggaatcca
     7981 aactaagtta tctacctgat taagactctc aaaatcactc gggaggatag tcaaggtatt
     8041 taaatcgtgc aaactatgaa taagaacttc ccaatcattg tgtttaaaga caatatctgg
     8101 ttcaaaaccg agagctcggc attttctagg aagcatttcg cctaacatgt agtgatcgtt
     8161 taaagaagca atcttatagc cttttaaatc tttaagtttt aactgaggat gttgcgccaa
     8221 agggtgctgt ttgaggagaa cgatactgac cttatagcct tttgtggacg tttgtaatag
     8281 ctcaatggta atatcctttt gaatacttag aaaggagagg agaccaatat cgatttttcc
     8341 ttgggacaat aattcttata atttgcgaga accatcctgt ataagtgata cttcaacatt
     8401 tgagtgagta gccataaaga ttgaaatttg tttcatgaat tgtatagcaa acagtgatgt
     8461 taattcaaca cgaatcatct ctttttttct tgatttaatt gctgaatatc cgcaacaatt
     8521 tgattaaagt catccacaag gtctttgcct ttgtgataaa gaatatctcc agcttcggtt
     8581 agtagtagct gtcaatcact ttgtgtaaaa agcgtggtgt tcaaactagg actctagcct
     8641 tttaattgat tgagaaagag tatgttgcgt tacaaacaaa cttttagcag cgtgggaatg
     8701 attttttgtt tcagcaactg caataaaata ggttaattat ctaatatcca tagtagatcc
     8761 ttcatgatta gtcagggaat tgcgtctcta cttggtttac aacctatttt gatgtctctc
     8821 cttattgcca tgattttctg cttccttatt gtttctccaa ttacaacggt aggaattgct
     8881 cttgcgatta acttatctgg tattggttca ggtgctgcaa acttaggtat ttgtgccgca
     8941 agctttggac tttgtttagc aggttgggct gttaattcaa aaggaacttc acttgctcac
     9001 gtcttgggat caccgaaaat ttcaatggcc aacgttttat caaaaccaaa aatcatgttg
     9061 ccaatgttat gttctgcagc tgtacttggt gttattggtg ctatctttaa tattcaagga
     9121 acacctgcta gtgcaggctt tgggattagt tgtttgatcg gacctatcaa tgcccttaat
     9181 ttagctaaag gcggatggtc tctagtaaat atcctactta tcattatcat ttttgtaagg
     9241 gcaccaattg ttctcaatat gatctttaac taccttttta tcaaggtgct taaagtgatt
     9301 gatccaatgg attacaaact tgatatctaa gaaaggaact tttgatgaaa ttaaaattat
     9361 ataatgttag aggcgaagaa gcagtcttag caaaaaaatg ggctgatgac aatgggattg
     9421 agatttcctt gacagagtct tccttaactc ctgaaacggt taaagaagct gaaggctttg
     9481 acgggattgc caatgcccaa attggtcctt tagatgatgc aatctatcct ctcttaaagg
     9541 aaatggggat taaacaaatc gctcagcgca gtgctggtgt cgatatgtat aaccttgatt
     9601 tggccaccga aaatgacatt attatcacaa atgttcctag ctattctcca gaatccattg
     9661 cagaatttac ggttactatt gcccttaatt taattcgtca tgtggagttg attcgtgaaa
     9721 atgttaaaaa acaaaatttc acttggagac tccctatccg cggccgtgtt ttaggtgata
     9781 tgacagttgc gattatcgga actggccgta ttggtctagc tactgctaaa atctttaaag
     9841 gttttggctg caaggtcgtt ggatatgata tttaccaaag cgatgctgcc aaagctgtct
     9901 tggactataa ggaatctgta gaagaagcga ttaaagatgc tgatcttgtt tccttacaca
     9961 tgccaccaac tgcagagaac acacaccttt tcaatgctga tttatttaaa tcattcaaaa
    10021 aaggggctat tttgatgaat atggcgcgtg gtgctctcat tgagacgcaa gatttactgg
    10081 atgctttgga tgcaggctta ctgagcggag ctggtattga cacttacgaa tttgaaggac
    10141 cttatatacc taagaatttt gaaggtcaag aaattacaga ttcactattt aaagctttga
    10201 ttaaccatcc taaggttatt tatacgcctc atgcagctta ttatactgat gaagccgtta
    10261 aaaacctagt tgaaggtgcc cttaatgcta cagtagagat tatcaaaact gggacaacga
    10321 caactcgtgt taactaacaa ctgatttgac gtccattata aaggaataat tttaaaaatt
    10381 cctttataat ggactttttt gcattagtcc gttataatag actgtaagaa aggggactct
    10441 tatgacatat atagcgctta ttggagatat tatccagtcc aaacaattga cggatcgttc
    10501 caaagttcaa aaaactttag cagcttattt agacgacctc aacaaaacct ttgctcctta
    10561 tattatttct aaattatccc taacgttggg agatgaattt caaggacttt ttcaggtgga
    10621 tactcctatt ttccatctga ttgatttgat taatcatcac atggatatcc ctattcgatt
    10681 tggagtagga gtaggttcta ttctaacaga catcaatcct gatattagta ttggggctga
    10741 tggacctgct tattggcatg ctcgtgaggc tattcgttat attcatcaaa aaaatgatta
    10801 tggtaatact acattagctc ttcggactgg tcatcacaac caggatgatg tattaaacag
    10861 tttactagca gctggagatg ctattaaagc caactggcga gctagtcaat gggaaatttt
    10921 tgacacgctt ttagatttgg gcatttatga ggaatacttt gatcaacaac gactaggaaa
    10981 gcaattatct cttagctcta gcgctttgtc aaaacgtcta aaaagtagtc atgttaaaat
    11041 ttatctgaga acacggcaga gtgcgctaaa ctgtctcaaa caaatcaagg aggaaactga
    11101 tgattaatgg tgtctctcac tacctagctc aaccccctac acttaccctg tttctcattt
    11161 gtcatgtgtt atcagactac cagttacaaa gtcagcaagt agctgattta aaagaaaaac
    11221 atttgactta tttaggttac cacttgattg gagttagcat tcccctaatt tgtttaaccc
    11281 tcattatccc acaagcatgg ttgatgagcc tattggttat gataagtcac gcgcttattg
    11341 actggctaaa gccaaagatg gctaactctc taaaatggaa aagagagtgg atttttctgc
    11401 tggatcaatg cttacatatc gctattagtt catttgctgg gctaaggtta gcaggggtga
    11461 ccttgcctaa ttggcttccg atatctattt tgatgaccgt tttatttatc ctagtcatta
    11521 ccaaaccaac taatattgtc tttaaactct ttttcagcaa ataccagcct gaccaaggag
    11581 aaaaaatgga cacgatcata ggagcggggg ctaccatagg aattctagag agaattgtta
    11641 ttggtttgtg tatgatcatg gggcaatttg cttcaatagg tctggtcttt accgctaaat
    11701 ctattgctcg ctacaataaa atttcggaaa gtccagcttt tgcagaatac tacctgattg
    11761 ggtctttatt tagtattctc agtgttttta tcgcagcatg gatttgtttc ttctagttga
    11821 aaagggttcc cgtagaaaga ggttatcgct tagtctcttt ctctttcttt ttctttcttc
    11881 ttatttctgt tataataagt caggtaacta cattagaaag atttgtgggt ctgtcatcta
    11941 agagatgtca ttcccgaaga ggtattagtg acttgtctca atcaactgca acttatatta
    12001 atgttattgg agctgggcta gctggttctg aagctgccta tcagattgct aagcgcggta
    12061 tccccgttaa attgtatgaa atgcgtggtg tcaaagcaac accgcaacat aaaaccacta
    12121 attttgccga attggtctgt tccaactcat ttcgtggtga tagcttaacc aatgcagtcg
    12181 gtcttctcaa agaagaaatg cgtcgcttgg attccattat tatgcgtaat ggtgaagcta
    12241 atcgtgtacc tgctggagga gcaatggctg ttgaccgtga ggggtatgca gagagtgtca
    12301 ctgcagagtt ggaaaatcat cctctcattg atgtcattcg tgatgaaatc acagaaatcc
    12361 ctgacgatgc cattacggtt atcgcgacgg gaccgctgac ttcggatgcc ctggcagaaa
    12421 aaattcacgc ggtaaatggt ggcgatggat tctatttcta cgacgcagca gcgcctatca
    12481 ttgataaatc tactattgat atgagcaagg tttacctcaa atctcgctac gataaaggcg
    12541 aagctgctta cctcaactgc cctatgacca aagaagaatt catggctttc catgaagctc
    12601 tgacaaccgc agaagaagcc ccgctgaatt cttttgaaaa agaaaagtat tttgaaggct
    12661 gtatgccgat tgaagttatg gctaaacgtg gcattaaaac catgctttat ggacctatga
    12721 aacccgttgg attggaatat ccagatgact atacaggtcc tcgcgatgga gaatttaaaa
    12781 cgccatatgc cgtcgtgcaa ttgcgtcaag ataatgcagc tggaagcctt tataatatcg
    12841 ttggtttcca aacccatctc aaatggggtg agcaaaaacg cgttttccaa atgattccag
    12901 ggcttgaaaa tgctgagttt gtccgctacg gcgtcatgca tcgcaattcc tatatggatt
    12961 caccaaatct tttaacggaa accttccaat ctcggagcaa tccaaacctt ttctttgcag
    13021 gtcagatgac tggagttgaa ggttatgtcg aatcagctgc ttcaggttta gtagcaggaa
    13081 tcaatgctgc tcgtttgttc aaaagagaag aagcacttat ttttcctcag acaacagcta
    13141 ttgggagttt gcctcattat gtgactcatg ccgacagtaa gcatttccaa ccaatgaacg
    13201 tcaactttgg catcatcaaa gagttagaag gcccacgcat tcgtgacaaa aaagaacgtt
    13261 atgaagctat tgctagtcgt gctttggcag atttagacac ctgcttagcg tcgctttaac
    13321 actaaaaaag agttcctttt cagttgagtt gctgaagagg acttttttac ttgctgattt
    13381 gagcgctagc tatgcaaaag aatgcacaaa aaatacatga atagactatg gtcactagaa
    13441 gcaatattat ataatgaata gtactcatta gttgattcag tttggaggtt ttagcatgca
    13501 gcagcaagtc gcaataacag aaacagtttt acgggatggt catcaaagtt tgatggcaac
    13561 gcgtttatct attgaggata tgcttcctgt ccttaccatc ttagacaaga ttggttatta
    13621 ttccctagag tgttggggag gagcaacctt tgatgcctgt attcgttttt tgaacgaaga
    13681 cccttgggaa aggctgcgca cgttaaaaaa aggcttacct aatacccgtt tgcaaatgtt
    13741 attaagaggc caaaaccttt taggctaccg tcattatgca gatgacatcg ttgacaaatt
    13801 cattagttta tcagctcaaa atgggattga tgttttccgc atttttgatg ccctaaatga
    13861 cccacgaaat atccagcaag ccttaagagc tgtgaaaaag acgggtaaag aggctcaact
    13921 gtgtattgcc tatacaacta gcccagtgca cacgcttaac tattaccttt ctttagtgaa
    13981 agaattggtt gagatgggag ctgattctat ctgcatcaaa gatatggctg gtattctaac
    14041 tcccaaagcg gctaaagagt tggtatctgg tatcaaagcc atgactaact tacctcttat
    14101 tgtgcatacc catgcaacta gtggcatttc tcagatgacc tatctagcag cagtagaagc
    14161 tggtgctgat agaattgata ctgctttgtc accttttagc gaaggcactt cacaacctgc
    14221 tacagaatcc atgtatttag ccttaaaaga agcaggttat gatatcacat tagatgaaac
    14281 gctactggaa caggctgcta atcaccttcg acaagctcgt caaaagtact tagcagatgg
    14341 cattctggat cccagtcttc tctttccaga cccaaggaca ctacaatacc aagttcctgg
    14401 aggcatgtta tctaatatgc tatctcagct gaaacaagcc aatgccgaat caaaattaga
    14461 agaagtttta gtagaagttc ctcgggtaag aaaagacttg ggttatcctc ccttagtaac
    14521 accgcttagc caaatggtcg ggactcaagc tgctatgaat gtgattttag gaaaacctta
    14581 ccagatggtg tctaaggaaa ttaaacaata cttggcaggc gactatggca aaacaccagc
    14641 accagtcaac gaagacttaa aacgaagtca aattggctca gctcctgtca ccacaaatcg
    14701 tcctgcagat caactaagtc ctgaattcga ggttttaaaa gcagaagtag cagatttagc
    14761 ccaaacggac gaagatgtgc tgacttatgc cctcttccca agcgtagcaa aaccgttttt
    14821 aacaaccaaa taccaaactg atgacgtcat taaagtgact gcctttatca aagcataata
    14881 ggctatctta atcagataga aacaaaaata tggagatcaa atgacctatt cctttattga
    14941 tatcttacaa gttaccttag tatccttgtt cttagtgtta acctgtttaa cagggattat
    15001 gggattaatg atgctaagtg gtaaattatt gtcacaagaa aaaaaaactc tctctcaaca
    15061 agcttccagc attcctcaag agcaagaagc tgacaagttg agtggagaag ctctcgaaac
    15121 tcttttagcc aaagacgaat tggctagaat tgctgttatg actagtcttg cttatgctag
    15181 ccaagaagag tcaggaaaac ggtttgaagt tattgccgtg gaaaggaaat cctaatgaaa
    15241 agatatgaag tgactgtcaa tggacaggtt tatgaagtga gtttacgtga actagctgat
    15301 ggagaaactg ttgaagttag ccagccagca gcacccgcta ctgagaaaga aatgaatgcc
    15361 aactctgctg gcggtggcat tcaggtaaag gctccaatgt ctggaacagt cttgtctatc
    15421 tttgctacag aaggaaaagc tgttaaaaaa ggagaagctg ttctggtctt agaggccatg
    15481 aaaatggaga atgaaattct agcacctgca gatggtctgg tttcaaaaat tcatgttgtg
    15541 gctaaccaaa cggtcgagtc tgaacaagtt ttgatttcat tctaggagga aaccatgcta
    15601 gacgtactca atcaaatggt ccaatcgtca ggattggctc atctaactgt taataatctt
    15661 atcatgattt gcttggcctg tttcttttta taccttggta tcaaaaagga atatgagcct
    15721 taccttatgg taccaatcgc ctttgggatt ttactcgtta atttgcctat ggcgggattg
    15781 atggacaacc ctgccaatgg taatcctggt ggccttcttt attacctata taagggaact
    15841 agcctaggga tttacccacc tttaattttt ctttgtttgg gggcatcaac tgactttggt
    15901 cccttgattg ccaatcctaa aaccatttta ctaggaggcg cagcacaagt tgggattttc
    15961 ttagcctttt tccttgctat tatgttaggc atgacacctc aagaagcggc ttctgtcggg
    16021 attattggtg gtgccgatgg accaacagct atttatgtga cgacaaagtt ggcgcctgat
    16081 ttactctcta ctatcgccct agcagcttat tcttacatgg ctctggtacc tattattcaa
    16141 cctcctatca ttaaactctt gactaccaag gcggaacgcc aagtgaaaat gactcaagca
    16201 agaactgttt cacaaaaaga aaaaatcatt ttcccgatta tggtaacaat ctttgtcagc
    16261 cttttggttc caagtgctac aaccttggtt ggctgtttga tgctgggaaa tctggtcaga
    16321 gaaattaaaa ttgttcctaa aattgtagag aatctccaac aagtggttat gttttgcatt
    16381 actatcattt taggattaac cgttggtgct aaggccaatg gagatctctt tttatcagcc
    16441 acaaccttga aaattattgc ccttgggcta atcgcctttg ctgctgggac agcagggggt
    16501 gtcttgatgg ggaaggtcat gtactattta tctggtaaca aagtgaaccc tatgatagga
    16561 gcagcaggtg tttcagctgt tccgatggca gcgcgagtgg tccaaaaggt cggacaagaa
    16621 gaagatccaa gtaatttctt actcatgcac gccatggggc ccaatgtagc tggcgttatt
    16681 ggctcagcca ttgcctcagg tgccttgctg gccttctttg gctaattgtg aaaaaggatt
    16741 agtaaattaa tcttaataaa tcattatcag gagttggaag caatctagct ccttttttag
    16801 tagaaagctc gagtgataaa ctattccaaa ataattataa aaaaagactg tcctgattgt
    16861 acggactata tcagttgact tttatagtct agctgaaata gcagtgcaaa actaagacac
    16921 tcgttttaaa gtagtttttc taaaaaagca aaataaaagg tcagagccaa taaatctgcc
    16981 gcgcccccag ggcttaaatg ctgattaatg aggcattgat tgtaggagga caaagccaat
    17041 cttagatcag ttgttgataa atcttgttgc aggagtagtc gcatatctgc cttaacgcct
    17101 ttccatgctt caatccctcc acgatgaatc agatttccat cttcaacaat agacatcaaa
    17161 taaacaagaa gacgaagctg actggtttcg gggtcatttt gacttatcat ctgacgaaag
    17221 tagggcaagg catggtctgt taaggtcgtg aatccctcgc ttgcctcacc ccgaggtcct
    17281 ttgatgccat aagttacaaa gagttgctcc ccataagtga actctttttt agtgttcaaa
    17341 tgaccaaggt ctgtttgaat caaatgtgtc gtcataggtt ttactaaacg acagatagct
    17401 agagtatctt ccttgctaaa acaccctaaa tcagtcatta agtgaggtgt tcttgctaga
    17461 taggccccag ttgcaccaag aagtaaagcc atggaaaaat tcaggccttt atgagtgtta
    17521 attccctgag tagcacaaaa catggtttcc tcggcctttt gacctagttg tctaagacgg
    17581 ttaaacagaa gaagtggctc ttcttttgca taagcaaaac ctgtttcgat ataagcctga
    17641 aaaaaaggag agagtgctat catactgtcg ataaaggtta taaaggacat gtcatcatgg
    17701 gcaccgttat caaatcgatc aactaaacca ggttttggag atagtgagac ttcataaagc
    17761 aaagctttta aggccagttg actaatactt gttagaactg ccttagtcat tttgctcagg
    17821 cctcatttct tttaagataa attcaagtga gctattcaag tgttcatgtg taatcaacgt
    17881 aatttgctca tgatctttgt tcttcatacc tcggtaaatc atccagtgtt cagatagagc
    17941 tcgtttacgg cgttcaactg aagaaatcga aatttttcta aagtagacca aataagcttg
    18001 caattctgtc acaatttctt ttaagcggac catttggcta tagctgtaaa tcaaattgtt
    18061 aaaggcatta aaattatcca aaatacgatt ggtgtcatcc tctgcgataa aggtttcaca
    18121 gtcttccaac aagttatgca tgactttaaa atcttcttct gtcattaaat gcatcgcttg
    18181 cactgttgcg agagtctcta gagcttttcg aatttcaaaa atttcacagg catccttgat
    18241 actaactcct ttgacaataa tgcctttttt aggaatgtgc tctacaaggt gttcttcaga
    18301 caataatccc aaagcgtagc gaataggtgt cctgctaata ttaagcgcaa tggaaaactc
    18361 tttttcatta atgcggcttc caacaggaat ttgtcgcaaa ataatggtct ttttaagagc
    18421 gttataaaag gctattttca aagggatatt tcttgatagg tcaagatttt gtttaacggc
    18481 ttcgataata ggattcatgt catctcctta atgctagtgt cctcacttta ttatacttaa
    18541 atttgtgaaa cattccaata ggactagatg agttctgaaa aattaaagcc atgctcacaa
    18601 aaggacatga ctttaatcat ctcataagga ataaggtagt agtgttatcg ttggtttatt
    18661 gtggaatgta aagtggcatt tgtcccatgg caataatggt taccacaaag ataacaaaga
    18721 tgataagggc atatttagca gcctcttttt gccattcccc catgtcaaga cctgtcaagc
    18781 gaagaagaag ataaatgaag gcaactaatg gactaagtaa gtggaaggct tgtcccatga
    18841 gggaagcaag tgccatagcc atgttactga aaccatattc agcaccagct tctgcaagaa
    18901 caggcaagat accatagtaa aaaccatcat tggagataaa gaaggtacca ggtgcagaaa
    18961 ctaaggcaat aacaagaccc cagaaacctg ccagttgttt tggaataatg gttgcaaaac
    19021 tttgtgcaag agcgctagcc ataccagaac cttggaaaag acccataaag ataccagcag
    19081 caaagactaa gataaccact tgaaccgcat caccagcatt atcaccaatg cgttttgatt
    19141 gatctttaag cactgggtaa ttgaccatca aggcgataca agttcccacc gcaaaaagaa
    19201 gaagcggtgc catagcaata gatttgttga aagagccagc aactaaccaa gtgattaatc
    19261 caatggttag gatagcattg aaaacaaagt ttttaggacg acgaataaaa agggtatctg
    19321 ggtcagtaat gtctgtgagt tgacgcatgt cttcttcaga caagtcaata acaccaagtc
    19381 ttgcacgttc tttacgcccc atgcttggag caacccaaca aatcacataa agaagagata
    19441 aaatcatacc cggtgcaaga tagccaagaa tttcaggacc gacaccaaga acagacatcg
    19501 cacgagcagt agggccaccc catggcagta agttcataat agtattttga agaataatca
    19561 agacacctag gttcatgatt ttcatgtcca attttttata gataggtaag aaagcagagc
    19621 aacaaattaa agtagtggtt gttccatcac cattaagaga tactgcggca gcaacgacag
    19681 ctgttgcgat aagcaccttc attggatcac ctttagcaaa gcgaatcatc ttttcagtaa
    19741 tcggatcaaa caatcctgca tctaacatga cagagaagaa caaaatggca aatagcaaca
    19801 tgatacctgt tttagcagta ttgttgatac catacataac cattggtccg atagctgtta
    19861 ggtctttagc aattccaccg tcaccaacaa aggcaacaaa tttggcatct gcattgaagt
    19921 cagctgaacc agtcagtata acagcaatcg tcatgattaa tggaatcatg accaaagcag
    19981 taaaaggggt catttttttc ttcattacca cgtacataaa gacaataatc atggcataag
    20041 ccagcattgt taataacatc attgttatct cctttttcaa gttatgattt cagtatagat
    20101 gaaagcgctt at
//
LOCUS       DAUGSW010000026        20011 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUGSW010000026 DAUGSW010000000
VERSION     DAUGSW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20011
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.026"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            240..1841
                     /locus_tag="VIB18_001181"
     CDS             240..1841
                     /locus_tag="VIB18_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8766190.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSSAIGVKDKELSKTLNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGRAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIE
                     KQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSP
                     SKSHSDKEVQKPEKPDNSVKQATSS"
     gene            2029..3276
                     /gene="mrp"
                     /locus_tag="VIB18_001182"
     CDS             2029..3276
                     /gene="mrp"
                     /locus_tag="VIB18_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Mrp"
                     /protein_id="HEQ8766191.1"
                     /translation="MSTRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKADLS
                     TQEHPRVTEAREKALEEVITKMPLEELQHTLAGSYRKNRELEKTIEKKDGEASFLSKV
                     LDETAKKYRESSDKYKQEIGQLKAAAEAEAQKALDALNNKNKQISDLTNENAQLKEAI
                     EGYVQTIQNASREIAAKQQELAAVKSQLEAKNAEIEALKQQDASKTEEIAKLQSEAAT
                     LENLLGSAKHELTELQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKLDAAN
                     AEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEE
                     LAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMPQTKRQLPSTGEETTNPF
                     FTAAALTVIASAGVLALKRKEEN"
     gene            3501..4469
                     /locus_tag="VIB18_001183"
     CDS             3501..4469
                     /locus_tag="VIB18_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407885.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEQ8766192.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVALTVLGAGFANQTEVKAEGV
                     SVGSDASLHNRITDLEEEREKLLNKLDKVEEEHKKDHEQLEKKSEDVERHYLRQLDQE
                     HKEQQERQKNLEELERQSQREIDKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASR
                     AAKKDLEAEHQKLKEEKQISDASRQGLSRDLEASREAKKKVEADLAEANSKLQALEKL
                     NKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQAN
                     RSRSAMTQQKRTLPSTGETANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            4678..5796
                     /gene="enn"
                     /locus_tag="VIB18_001184"
     CDS             4678..5796
                     /gene="enn"
                     /locus_tag="VIB18_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Enn"
                     /protein_id="HEQ8766193.1"
                     /translation="MARQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRADEP
                     KKMEVKESEKESQYKTLALRGENADLRNVNAKYLEKINAEEEKNKKLEATNKELNENY
                     YKLQDGIDALEKENEDLKTTLAKTTKENEISEASRKGLSRDLEASRAAKKELEAKHQK
                     LEAENKKLTEANQISEASRKGLSNDLEASRAAKKELEAKHQKLEADHQALEAKHQKLA
                     EEHQVSETSRKGLSRDLEASREANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAK
                     LDAQGKALKEQLAKQAEELAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPSQNKG
                     MRTQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            6131..9625
                     /gene="scpA/B"
                     /locus_tag="VIB18_001185"
     CDS             6131..9625
                     /gene="scpA/B"
                     /locus_tag="VIB18_001185"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEQ8766194.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTTVSEEVPSSKETKTPQTPDDAEETVADKANDPAPQAPAKTADTPATSKATI
                     RDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKAKARYQSKEDLEKAK
                     KEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPTETKEPYRLEGA
                     MPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETK
                     KAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPD
                     KQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIE
                     RGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDNS
                     KKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKL
                     SGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFS
                     PRQQGAGAVDAKKASAATMYVTNKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYY
                     QATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKN
                     GYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDA
                     KDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTF
                     AKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAQNLVAEVLDKEGNV
                     VWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISS
                     GAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDED
                     LPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEG
                     HSNKPEQDGSDQVPDKKPETKPEQDGSGQAPDKKPETKPEQDGSGQTPDKKPETKPEK
                     DSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTRDQLPTTNDKDTNRLHLLKLVMT
                     TFFLGLVAHIFKTKRTED"
     gene            9722..10957
                     /locus_tag="VIB18_001186"
     CDS             9722..10957
                     /locus_tag="VIB18_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEQ8766195.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSVQEN
                     TANTSQKWYDINQHGIIPVGISFEAAKKDFKEEVEKSRLSEEQQKTYKQKIETAKNKD
                     DLLFTYHSEYMTAVKNLPTSTEPTTQPVEVPVQETQASASDSMVTGDSTSVTADSPEE
                     TSSTETPAPSIPAVPEAPASSPESEKSSVAASSEENSSPETPAAPEAPALSEAPAQPA
                     ESEKPSVAAPSEETPSPETPEEPAAPSPSPESEEPSVAASSEETPSPETPAAPETPAL
                     PETPAQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVS
                     EQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIATMT
                     LMSLFGSLLVTKRQKETKK"
     gene            11193..12113
                     /gene="lmb"
                     /locus_tag="VIB18_001187"
     CDS             11193..12113
                     /gene="lmb"
                     /locus_tag="VIB18_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEQ8766196.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            12126..14597
                     /locus_tag="VIB18_001188"
     CDS             12126..14597
                     /locus_tag="VIB18_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEQ8766197.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNP
                     GQGHQPDNGGYHPEPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGL
                     IFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSK
                     PSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHY
                     IGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVG
                     YMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKNHYRYDIVDTGIEPRLAVDVSSLP
                     MHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHE
                     ESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETF
                     VWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQAD
                     KSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQP
                     EGVQFYNKNGELVTYDIKTLQQINP"
     gene            14766..14966
                     /locus_tag="VIB18_001189"
     CDS             14766..14966
                     /locus_tag="VIB18_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8766198.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(15048..15674)
                     /locus_tag="VIB18_001190"
     CDS             complement(15048..15674)
                     /locus_tag="VIB18_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766199.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHDFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(15658..16461)
                     /locus_tag="VIB18_001191"
     CDS             complement(15658..16461)
                     /locus_tag="VIB18_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766200.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARSLWRTLPQQDFLKGVTHDLRG"
     gene            complement(16473..17294)
                     /locus_tag="VIB18_001192"
     CDS             complement(16473..17294)
                     /locus_tag="VIB18_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766201.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(17291..18268)
                     /locus_tag="VIB18_001193"
     CDS             complement(17291..18268)
                     /locus_tag="VIB18_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766202.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKA"
     gene            complement(18381..20009)
                     /locus_tag="VIB18_001194"
     CDS             complement(18381..20009)
                     /locus_tag="VIB18_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8766203.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         7057 a         3963 c         3912 g         5079 t
ORIGIN      
        1 aaatgtcgct aaaaaaatag atagaagagt ctaaaatttc agttttaggt cacgttttat
       61 gaatgtaaat cagaatgatg accttaagtt gtgatttgcg cgtcattgac cgctttcctc
      121 gttttaatga aagaatttga aagatatttt atggtatact tttccttaat atggttcata
      181 cggacttgat aaatctattc acaaaaataa taaaaaatta agataaggac atgaagttaa
      241 tgcatgtaag taaattattt actagccaac aatggagaga attgaaactg atctcatatt
      301 taacagaaaa ctccagtgct atcggagtta aagataagga gcttagcaag actctcaata
      361 tttccatgtt aacattacag tcatgtctca ctaatatgca gttcatgaaa gaagtaggtg
      421 gaattaccta caaagacggc tatattaaca tttggtatca ccagtgttgt gggctacaag
      481 aggtctatca aaaagctctt cgagaatcgc cttctttgaa attactggag cttttgtttt
      541 tcagagactt tagttcctta gaagagttag ctgaagagct gtttgtcagc ttatctaccc
      601 tcaaacgcct catcaaaaaa accaacactt acttgtctca tacctttgct attagtatcg
      661 tgacaagtcc agtgcaggta tcaggagatg agaggcaaat ccgcctgttt tacctcaagt
      721 atttttcaga agcctataaa atctcagaat ggccatttgg ggacatttta aacctgaaaa
      781 actgtgaacg cctattgagc ttattgatca aagaagtaga tgtcaaagtt cattttacac
      841 tatttcagca cttaaaaatc ttaagtggtg tcaacttgat ccgttactac aaggggtatt
      901 cttgcagtta taacaataaa aaaaccagtc accgtttttc tcaactcatc caacattcct
      961 cagaaatcca ggatctttct cgcttgttct acctcaaatt tgggttacat ctcgacgagt
     1021 ataccatagc tgaaatgttt tctaaccatc ttaacgacaa gctagaaatt ggccgtgctt
     1081 ttgagattat caatcaagac ccaacatcag gaggcagaca agtaaccaac tggatccatc
     1141 tattagatga gatggaaatc aagctcaatc tcagcatcac caataaatac gaagttgccg
     1201 taaccctcca taacgcttcg gtgttaaacg aagaagacat tacagccaat tatttgctgt
     1261 ttgattataa aaagagttac ctgaactttt accaaaaaga acaccctcgt atctatgagg
     1321 cctttgtgac aagtgtcgag aagctgatgc aggcagataa tgctcaagtt agcaaagaac
     1381 tgatcaatca gctcacttat tgtttcttta ttacctggga aaatagtttc ttaaaagtaa
     1441 atcaaaaaga tgaaaaagta cgactcctag tgatagagag aagttacaat agtgtcggta
     1501 attttttgaa aaagtacatc ggtgagtttt tcagcattac taattttgat gagttagatt
     1561 gtttgacaat tgatctagta gagattgaaa aacagtacga tgttatcgtg acagatgtta
     1621 tggtgggtaa aagcgaagag ttagagattt tctttttcta caagatgatc ccagaagcta
     1681 ttattgatag attaaacgaa tttttgaacg ttagtttcac agataacaac gttatggtca
     1741 aaaacctcga agccccttcc ccttcaaaat ctcatagcga caaagaggta caaaaaccag
     1801 aaaagccaga caattcagtt aaacaagcaa catcatcata ggatttcaga cgtcatggta
     1861 agaaaaaaag aatcatttac agcccataga ggtaaggtca aaagctgaaa acagctcaaa
     1921 aaaactgacc tttacctttt ggcttttttt atttagaata attttattgg agagatgctt
     1981 aataatttaa gcacaattct tagaaagtta agaaataagg agtaaacaat gtctacaaga
     2041 aatccaaaca aacactactc actgagaaag ttaaaaacag gtactgcatc agtagcagta
     2101 gctttgacag ttttggggac tggattagca aacacaactg atgtaaaggc tgacttaagt
     2161 actcaggagc atcctagagt aacagaagca agagaaaaag ctttagaaga agttataaca
     2221 aagatgcctt tagaagaact tcagcacact ctagcaggat cttaccgcaa gaacagagag
     2281 ctggaaaaga caatcgagaa aaaggatggc gaagcttctt tcctttctaa agttttagac
     2341 gaaactgcaa aaaaatatag agaatctagc gacaagtata aacaagagat tggacaacta
     2401 aaagcagcag cagaagcaga agctcaaaaa gcattagatg cattaaataa caaaaacaag
     2461 caaatctcag acttaaccaa cgaaaacgca cagttaaaag aagccattga aggttatgtg
     2521 caaactatcc aaaacgctag ccgtgaaatc gcagcaaaac aacaagaact tgcagctgta
     2581 aaaagccagt tagaggcaaa aaatgctgag attgaggcat tgaaacaaca agatgcctct
     2641 aaaactgaag aaattgctaa attgcaatca gaagcagcaa ctttagaaaa cctcctaggt
     2701 tcagctaagc atgagttgac tgaattgcaa gctaagctag atacagcaac tgctgaaaaa
     2761 gcaaaactag aatcacaagt aacaacctta gaaaacctcc taggttcagc taagcgtgaa
     2821 ttgactgatc tgcaagctaa gctagatgca gctaacgctg aaaaagaaaa gctccaatca
     2881 caagcagcag ccctagaaaa acaactagaa gcaactaaaa aagagttagc tgatttacag
     2941 gctaaattag cagcaaccaa ccaagaaaaa gaaaagttag aagctgaagc aaaagctctt
     3001 aaagagcaat tagcaaaaca agctgaagag cttgctaagc taaaagcaga taaagcttca
     3061 ggagctcaaa aaccagatac caaacctggc aataaagagg ttccaacaag accgtcacaa
     3121 acaaggacaa acactaataa agctcctatg ccgcaaacaa agagacaatt accctcaaca
     3181 ggcgaagaaa caaccaaccc attcttcact gcagcagcat tgacagtgat cgcatctgca
     3241 ggcgtacttg ccctaaaacg caaagaagaa aactaagccc aacccacact atcttttcta
     3301 gcccaagaaa aaaacaaaaa aagaggaaga ccattcctct ttttttgaac ggttaaacag
     3361 caaaaaggtc aaaaaggtac taaagtctca aaaacctggt ctttaccttt taccgcttat
     3421 tatttagaat agaattatta gagagaagtc ttagaaaaat gaggctaatt ccctaaagat
     3481 gaaaaaataa ggagcaaata atggctagaa aagatacgaa taaacagtat tcgcttagaa
     3541 aattaaagac aggtacagcc tcagtagcag ttgctttgac tgttttagga gcaggctttg
     3601 caaaccaaac agaagttaag gcggaagggg tttctgtagg ttcagatgca tcactacata
     3661 accgcattac agaccttgaa gaggaaagag aaaaattatt aaataaatta gataaagttg
     3721 aagaagagca taaaaaagat catgaacaac ttgaaaaaaa atcagaagat gtagaacgtc
     3781 actacctcag acaactagat caagagcata aagaacaaca agaacgtcaa aaaaatctag
     3841 aggaactcga acgccaaagt caacgagaaa tagacaagcg ttatcaagaa caactccaaa
     3901 aacaacaaca attagaaaca gaaaagcaaa tctcagaagc tagtcgtaag agcctaagtc
     3961 gtgaccttga agcgtctcgt gcagctaaaa aagaccttga agctgagcac caaaaactca
     4021 aagaggaaaa acaaatctca gacgcaagcc gtcaaggtct aagccgtgac cttgaagcgt
     4081 ctcgcgaagc taagaaaaaa gtagaagcag acttagcaga agcaaatagc aaacttcaag
     4141 cccttgaaaa actaaacaaa gagcttgaag aaggtaagaa attatcagaa aaagaaaaag
     4201 ctgagttaca agcaagacta gaagctgaag caaaagctct taaagagcaa ttggctaaac
     4261 aagctgaaga acttgctaaa ctaaaaggca accaaacacc aaacgctaaa gtagccccac
     4321 aagctaaccg ttcaagatca gcaatgacgc aacaaaagag aacgttaccg tcaacaggcg
     4381 aaacagctaa cccattcttt acagcagcag ctgcaacagt gatggtatct gcaggtatgc
     4441 ttgctctaaa acgcaaagaa gaaaactaag cattagactg atgctaaagc taagagagaa
     4501 tcgaatgatt ctctcttttt gagtggttaa gtaactaata atctcagtta gaccaaaaaa
     4561 tgggaatggc tcaaaaagct ggcctttact ccttttgatt aaccatatat aataaaaaca
     4621 ttaggaaaat aatagtaata ttaagtttgt ttcctcaata aaatcaagga gtagataatg
     4681 gctagacaac aaacaaagaa aaattattca ctacggaaac taaaaaccgg tacggcttca
     4741 gtagccgttg ctttgaccgt tttgggcgca ggttttgcaa accaaacgga agtaagagct
     4801 gatgaaccta aaaaaatgga agtaaaagaa agtgaaaaag agtcccagta taagacgttg
     4861 gctttaagag gtgaaaatgc tgaccttaga aatgtaaatg caaaatattt agagaaaatt
     4921 aacgcagaag aagaaaaaaa taaaaagctt gaagcaacta ataaagagct aaatgagaat
     4981 tattacaaat tacaagatgg tattgatgct ctagaaaaag aaaacgaaga tctcaaaaca
     5041 actttagcta agactactaa agaaaatgag atttcagaag ctagccgtaa agggttgagc
     5101 cgagacttag aagcttctcg tgcagctaaa aaagagctag aagctaagca tcaaaaatta
     5161 gaagcagaaa acaaaaaact aacagaagcc aatcagattt cagaagctag tcgtaaaggt
     5221 ctaagtaacg acttagaagc ttctcgtgca gctaaaaaag aactagaagc taagcaccaa
     5281 aaattagagg ctgatcacca agccctagaa gctaagcacc aaaaattagc agaagaacat
     5341 caagtttcag agactagccg taagggtcta agccgtgacc ttgaagcatc acgtgaagct
     5401 aataagaagg ttacatctga gttaacacaa gcaaaagctc aactctcagc gcttgaagaa
     5461 agtaagaaat tatcagaaaa agaaaaagct gagttacaag caaaactaga tgcacaagga
     5521 aaagccctca aagaacaatt agcaaaacaa gctgaagaac ttgcaaaact aagagctgaa
     5581 aaagcagcag gttcaaaaac acctgctacc aaaccagcta ataaagaaag atcaggtaga
     5641 gctgctcaaa cagctacaag acctagccaa aataaaggaa tgagaacaca attaccgtca
     5701 acaggcgaag cagctaaccc attctttaca gcagcagctg caacagtaat ggtatctgca
     5761 ggtatgcttg ctctaaaacg caaagaagaa aactaagcct ttagaacttg gtttttgtaa
     5821 cggtgcaata gacaaaagca agcaaggcca aaaactgaga aagtcctaaa aagctggcct
     5881 ttacccctaa agattaatgt tttataatga agatgttagt aatataattg ataaatgaga
     5941 tacatttaat cattatggca aaagcaagaa aaatagctgt atcatatgca aataacccct
     6001 gtttgctctt taaaaaagac gttatcctta tttctccacg cacagatgga cagctaggag
     6061 agaatcgttt gattctctct tttcttaatg gtcataaaga caaagtctct catcatgaaa
     6121 ggacgacaca ttgcgtaaaa aacaaaaatt accatttgat aaacttgcca ttgcgctcat
     6181 gtctacgagc atcttgctca atgcacaatc agacattaaa gcaaatactg tgacagaaga
     6241 cactcctgct accgaacaag ccgtagaaac cccacaacca acaacggttt ctgaggaagt
     6301 accatcatca aaggaaacca aaactccaca aactcctgat gacgcagaag aaacagtagc
     6361 agataaggct aatgatccag cccctcaagc tcctgctaaa actgctgata caccagcaac
     6421 ctcaaaagcg actattaggg atttgaacga cccttctcag gtcaaaaccc tgcaggaaaa
     6481 agcaggcaag ggagctggga ctgttgttgc agtgattgat gctggttttg ataaaaatca
     6541 tgaagcgtgg cgtttaacag acaaagccaa agcacgttac caatcaaaag aagatcttga
     6601 aaaagctaaa aaagagcacg gtattaccta tggtgagtgg gtcaatgata aggttgctta
     6661 ttaccacgac tatagtaaag atggtaaaac cgctgtcgat caagagcacg gcacacacgt
     6721 gtcagggatc ttgtcaggaa atgctccaac tgaaacgaaa gaaccttacc gcctagaagg
     6781 tgcgatgcct gaggctcaat tgcttttgat gcgtgtcgaa attgtaaatg gactagcaga
     6841 ctatgctcgt aactatgctc aagctatcag agatgctgtc aacttgggag ctaaggtgat
     6901 taatatgagc tttggtaatg ctgcactagc ttacgccaac cttccagacg aaaccaaaaa
     6961 agcttttgac tacgccaaat caaaaggtgt tagcattgtg acctcagctg gtaatgatag
     7021 tagctttggg ggcaagaccc gtctacctct agcagatcat cctgattatg gggtggttgg
     7081 gacacctgca gcggcagact caacattgac agttgcttct tacagcccag ataaacagct
     7141 cactgaaact gctacggtca aaacagccga tcagcaagat aaagaaatgc ctgttctttc
     7201 aacaaaccgt tttgagccaa acaaggctta cgactatgct tatgctaatc gtgggatgaa
     7261 agaggatgat tttaaggatg tcaaaggcaa aattgccctt attgaacgtg gtgatattga
     7321 tttcaaagat aagattgcaa acgctaaaaa agctggtgct gtaggggtct tgatctatga
     7381 caatcaagac aagggcttcc cgattgaatt gccaaatgtt gatcagatgc ctgcggcctt
     7441 tatcagtcga aaagacggtc tcttattaaa agacaattct aaaaaaacca tcaccttcaa
     7501 tgcgacacct aaggtattgc caacagcaag tggcaccaaa ctaagccgct tctcaagctg
     7561 gggtctgaca gctgacggca atattaagcc agatattgca gcacccggtc aagatatttt
     7621 gtcatcagtg gctaacaaca agtatgccaa actttctgga actagtatgt ctgcgccatt
     7681 agtagcgggt atcatgggac tgttgcaaaa gcaatatgag acacagtatc ctgatatgac
     7741 accatcagag cgtcttgatt tagctaaaaa agtattgatg agctcagcaa ctgccttata
     7801 tgatgaagat gaaaaagctt atttttctcc tcgccaacaa ggagcaggag cagtcgatgc
     7861 taaaaaagct tcagcagcaa cgatgtatgt gacaaataag gataatacct caagcaaggt
     7921 tcacctgaac aatgtttctg ataaatttga agtaacagta acagttcaca acaaatctga
     7981 taaacctcaa gagttgtatt accaagcaac tgttcaaaca gataaagtag atggaaaaca
     8041 ctttgccttg gctcctaaag cattgtatga gacatcatgg caaaaaatca caattccagc
     8101 caatagcagc aaacaagtca ccgttccaat cgatgctagt cgatttagca aggacttgct
     8161 tgcccaaatg aaaaatggct atttcttaga aggttttgtt cgtttcaaac aagatcctaa
     8221 aaaagaagag cttatgagca ttccatatat tggtttccga ggtgattttg gcaatctgtc
     8281 agccttagaa aaaccaatct atgatagcaa agacggtagc agctactatc atgaagcaaa
     8341 tagtgatgcc aaagaccaat tagatggtga tggattacag ttttacgctc taaaaaacaa
     8401 ctttacagca cttaccacag agtctaaccc atggacgatt attaaagctg tcaaagaagg
     8461 ggttgaaaac atagaggata tcgaatcttc agagatcaca gaaaccattt ttgcaggtac
     8521 ttttgcaaaa caagacgatg atagccacta ctatatccac cgtcacgcta atggcaagcc
     8581 atatgctgcg atctctccaa atggggatgg taacagagat tatgtccaat tccaaggtac
     8641 tttcttgcgt aatgctcaaa accttgtggc tgaagtcttg gacaaagaag gaaatgttgt
     8701 ttggacaagt gaggtaaccg agcaagttgt taaaaactac aacaatgact tggcaagtac
     8761 acttggttca acccgttttg aaaaaacgcg ttgggacggt aaagataaag acggcaaagt
     8821 tgttgctaac ggaacctaca cttatcgtgt tcgctacact ccgattagct caggtgcaaa
     8881 agaacaacac actgattttg atgtgattgt agacaatacg acacctgaag tcgcaacatc
     8941 ggcaacattc tcaacagaag atcgtcgttt gacacttgca tctaaaccaa aaaccagcca
     9001 accggtttac cgtgagcgta ttgcttacac ttatatggat gaggatctgc caacaacaga
     9061 gtatatttct ccaaatgaag atggtacctt tactcttcct gaagaggctg aaacaatgga
     9121 aggcgctact gttccattga aaatgtcaga ctttacttat gttgttgaag atatggctgg
     9181 taacatcact tatacaccag tgactaagct attggagggc cactctaata agccagaaca
     9241 agatggttca gatcaagtac cagacaaaaa accagaaact aaaccagaac aagacggttc
     9301 aggtcaagca ccagacaaaa aaccagaaac taaaccagaa caagacggtt caggtcaaac
     9361 accagacaaa aaaccagaaa ctaaaccaga aaaagatagt tcaggtcaaa caccaggtaa
     9421 aactcctcaa aaaggtcaac cttctcgtac tctagagaaa cgatcttcta agcgtgcttt
     9481 agctacaaaa gcatcaacaa gagatcagtt accaacgact aatgacaagg atacaaatcg
     9541 tttacatctc cttaagttag ttatgaccac tttcttcttg ggattagtag ctcatatctt
     9601 taaaacaaaa cgcactgaag attagtacaa ctgatcagat ggctactatt gatgatgagt
     9661 tagataagtc ttcttttcaa aagaaggcat agcagtataa aaatagatat gtgaggacaa
     9721 tatgcgtaga gcagaaaata acaaacacag ccgctattcc attcgcaaac tgagcgttgg
     9781 ggtaacgagt atagcaattg cgagtctctt tttgggaaaa gttgcctatg ccgtagatag
     9841 cgttcaagaa aacacagcta atacatccca aaaatggtat gatattaatc agcatggcat
     9901 tattcctgta ggtataagct ttgaagctgc caaaaaagat tttaaagaag aagtagaaaa
     9961 atcacgtttg tctgaagaac aacagaaaac gtataaacaa aaaattgaaa ctgcaaaaaa
    10021 taaagacgac ctattattca catatcatag tgagtacatg acagccgtta agaatcttcc
    10081 aacgtctact gagcctacta ctcagccagt tgaggtaccc gtgcaggaga cacaggcatc
    10141 agcttcagat tcgatggtga caggtgattc aacatcagtt acggctgatt ctcctgagga
    10201 aacctcatct acagaaaccc cagctccatc aattccagcg gtcccagaag ccccagcttc
    10261 atcacctgag agtgagaaat cttcagtagc agcttcttct gaggaaaact catctccaga
    10321 aactccagcg gccccagaag ccccagcttt atctgaggct ccagctcaac cagctgagag
    10381 tgagaaacct tcagtagcag ctccttctga ggaaacccca tctccagaaa ctcctgaaga
    10441 accagcagct ccatctccat cacctgagag tgaggaacct tcagtagcag cttcttctga
    10501 ggaaacccca tctccagaaa ctccagcagc cccagaaacc ccagctttac ctgagactcc
    10561 agctcaacca gctgagagtg aagaatcttc agtagcagct acgacaagcc cgtctccatc
    10621 aactccagcc gaatcagaga ctcagacgcc accagctgtt actaaagact ctgataagcc
    10681 atcttcagca gctgaaaaac cagcagcctc ttcacttgtt tcagaacaaa ccgttcaaca
    10741 accaacttca aagagatctt ctgataaaaa agaagagcaa gaacagtctt actctccaaa
    10801 tcgctcattg tcaagacagg ttagggccca tgagtcaggt aagtacttgc cttcaacagg
    10861 tgaaaaagca cagccactct ttatagctac tatgactttg atgtctctat ttggcagtct
    10921 tttagtcaca aaacgccaaa aagaaactaa aaaatagtat tacttaaact gataagagct
    10981 tatttaatag agagaaccaa tttggttctc tctatttttt tagatgtgct gcctcatcaa
    11041 aaagaagtta ggacaaatag ctgtcaacaa ttgtcttttg cttatctctt cagttgctgt
    11101 gataaaagat ggtagttgcc attgacaaag cattgataaa ggagtaaaat taactggtta
    11161 ataactggtt aaattataat tgaggaggta ctatgaaaaa aggttttttt ctcatggcta
    11221 tggtcgtgag tttagtaatg atagcagggt gtgataagtc agcaaacccc aaacagccta
    11281 cgcaaggcat gtcagttgta accagctttt acccaatgta tgcgatgaca aaagaagtat
    11341 ctggagacct caatgatgtg aggatgatcc aatcaggtgc aggcattcat tcctttgaac
    11401 cgtctgtaaa tgatgtggca gctatttatg acgcggattt gtttgtttac cattcacata
    11461 ccttagaagc ttgggcaagg gatctagacc ctaatttaaa aaaatcaaag gttgatgtgt
    11521 ttgaagcgtc aaaacctctg acactagata gagtcaaagg gctagaagat atggaagtca
    11581 cacaaggcat tgaccctgcg acactttatg acccacatac ctggacagat cccgttttag
    11641 ctggtgagga agctgttaat atcgctaaag agctaggacg tttggatcct aaacacaaag
    11701 acagttacac taaaaaggct aaggctttca aaaaagaagc agagcaacta actgaagaat
    11761 acactcaaaa atttaaaaag gtgcgctcaa aaacattcgt gacgcagcac acggcatttt
    11821 cttatctggc taaacgattc ggcttgaaac aacttggtat ctcgggtatt tctccagagc
    11881 aagagccctc tcctcgccaa ttgaaagaaa ttcaagactt tgttaaagaa tacaacgtca
    11941 agactatttt tgcagaagac aatgtcaatc ccaaaattgc tcatgctatt gcgaaatcaa
    12001 caggagctaa agtaaagaca ttaagtccac ttgaagctgc tccaagcgga aacaagacat
    12061 atctagaaaa tcttagagca aatttggaag tgctctatca acagttgaag taaaggagat
    12121 tattagtgaa gaaaacatat ggttatatcg gctcagttgc tgccatttta ctagctactc
    12181 atattggaag ttaccaactt ggtaagcatc atatgggttc agcaacaaag gacaatcaga
    12241 ttgcctatat tgatgatagc aaaggtaagg caaaagcccc taaaacaaac aaaacgatgg
    12301 atcaaatcag tgctgaagaa ggcatctctg ctgaacagat cgtagtcaaa attactgacc
    12361 aaggctatgt gacctcacac ggtgaccatt atcattttta caatgggaaa gttccttatg
    12421 atgcgattat tagtgaagag ttgttgatga cggatcctaa ttaccatttt aaacaatcag
    12481 acgttatcaa tgaaatctta gacggttacg ttattaaagt caatggcaac tattatgttt
    12541 acctcaagcc aggtagcaag cgcaaaaaca ttcgaaccaa acaacaaatt gctgagcaag
    12601 tagccaaagg aactaaagaa gctaaagaaa aaggtttagc tcaagtggcc catctcagta
    12661 aagaagaagt tgcggcagtc aatgaagcaa aaagacaagg acgctatact acagacgatg
    12721 gctatatttt tagtccgaca gatatcattg atgatttagg agatgcttat ttagtacctc
    12781 atggtaatca ctatcattat attcctaaaa aagatttgtc tccaagtgag ctagctgctg
    12841 cacaagccta ctggagtcaa aaacaaggtc gaggtgctag accgtctgat taccgcccga
    12901 caccagcccc aggtcgtagg aaagccccaa ttcctgatgt gacgcctaac cctggacaag
    12961 gccatcagcc agataacggt ggctatcatc cagagcctcc taggccaaat gatgcgtcac
    13021 aaaacaaaca ccaaagagat gagtttaaag gaaaaacctt taaggaactt ttagatcaac
    13081 tacaccgcct tgatttgaaa taccgtcatg tggaagaaga tgggttgatt tttgaaccga
    13141 ctcaagtgat caaatcaaac gcttttgggt atgtggtgcc tcatggagat cattatcata
    13201 ttatcccaag aagtcagtta tcacctcttg aaatggaatt agcagatcgg tatttagccg
    13261 gccaaactga ggacaatgac tcaggttcag agcactcaaa accatcagat aaagaagtga
    13321 cacatacctt tcttggtcat cgcatcaaag cttacggaaa aggcttagat ggtaaaccat
    13381 atgatacgag tgatgcttat gtttttagta aagaatccat tcattcagta gataaatcag
    13441 gagttacagc taaacacgga gatcatttcc actatatagg atttggagaa cttgaacaat
    13501 atgagttgga tgaggtcgct aactgggtga aagcaaaagg tcaagctgat gagcttgctg
    13561 ctgctttgga tcaggaacaa ggcaaagaaa aaccactctt tgacactaaa aaagtgagtc
    13621 gcaaagtaac aaaagatggt aaagtgggct atatgatgcc aaaagatggc aaggactatt
    13681 tctatgctcg tgatcaactt gatttgactc agattgcctt tgccgaacaa gaactaatgc
    13741 ttaaagataa gaaccattac cgttatgaca ttgttgacac aggtattgag ccacgacttg
    13801 ctgtagatgt gtcaagtctg ccgatgcatg ctggtaatgc tacttacgat actggaagtt
    13861 cgtttgttat ccctcatatt gatcatatcc atgtcgttcc gtattcatgg ttgacgcgcg
    13921 atcagattgc aacaatcaag tatgtgatgc aacaccccga agttcgcccg gatgtatggt
    13981 ctaagccagg gcatgaagag tcaggttcgg tcattccaaa tgttacgcct cttgataaac
    14041 gtgctggtat gccaaactgg caaattatcc attctgctga agaagttcaa aaagccctag
    14101 cagaaggtcg ttttgcaaca ccagacggct atattttcga tccacgagat gttttggcca
    14161 aagaaacttt tgtatggaaa gatggctcct ttagcatccc aagagcagat ggcagttcat
    14221 tgagaaccat taataaatct gatctatccc aagctgagtg gcaacaagct caagagttat
    14281 tggcaaagaa aaacgctggt gatgctactg atacggataa acccaaagaa aagcaacagg
    14341 cagataagag caatgaaaac caacagccaa gtgaagccag taaagaagaa gaaaaagaat
    14401 cagatgactt tatagacagt ttaccagact atggtctaga tagagcaacc ctagaagatc
    14461 atatcaatca attagcacaa aaagctaata tcgatcctaa gtatctcatt ttccaaccag
    14521 aaggtgtcca attttataat aaaaatggtg aattggtaac ttatgatatc aagacacttc
    14581 aacaaataaa cccttaacca aaagaagatc tcattgttaa agcactgctt tgtcaaagca
    14641 agttacggtg attttgaagt cattttatgt aacgagtagt gataaaagtt ggataatagc
    14701 ggttttcttt tgcaaagaaa tggtatccat gttagaataa taaaaaaaag aggaggattc
    14761 taatcatgtc agaagaaaaa ttaaaatcaa aaattgagca agcatctggt ggcctaaaag
    14821 aaggtgctgg taagttgaca ggtgataaag agctagaagc aaaaggattt gttgaaaaaa
    14881 caattgctaa aggcaaagaa cttgcagacg atgcaaaaga agcggttgaa ggtgctgtag
    14941 atgccgttaa ggaaaaatta aaataattaa aaaaaccagc ttacagctgg tttttttaat
    15001 ggtgtgattt tgttagaaaa agactcaata ggtaataacc gtaggtgtta ggtatgcttg
    15061 aacagttgag tacgattctc ttcaatcata tagcacgcgt cacagagttt ttctaacata
    15121 tcaaaatcat gactaataat gatgagacct aaatttctat cctttacaat ctccaacagg
    15181 cttttccata cactagcttg tgtaatgcta tccaacatag tagtcatttc atctgcaata
    15241 aggtatttcg tctctggatg taatgaacgc acaatcgaaa agcgttgcaa ttcccctccc
    15301 gagagttcac taggacgacg ctttagccat ttttcttgaa tgccaaaagc atctcgcaaa
    15361 tcttgacttg gatagtaggc ttcttccaaa ctttttttca taggccataa aggattcatg
    15421 gtttgttcag gatgttgttg gataagttgt acaggtctaa atgctttgtt aggcaaatga
    15481 ctgccatcaa ctaatacttc accagattta ggctgcaaaa aaccggcaag cactctggat
    15541 aaactcgttt ttccacaccc actttgtcca aatatcccta agatttgacc aggtgctacc
    15601 tctaaatcaa tctccttaaa aagccattga tcttttttat gataaaagcc aagcttttta
    15661 gcctctaagg tcatgagtaa ctcctttcaa aaagtcttgc tgagggagtg tgcgccataa
    15721 acttctagca aattctgttt gtaattgctc cccacctccg ctaaaaaagc tagctggggc
    15781 tgtttcaata gcttttccct ctttaaaaat agttatacga tccgcaattt gactagctgc
    15841 tacaatatca tgagtgataa atatgacgct tattccttta tctgcaaagg agcgtagttg
    15901 atctaaaacc atttgcagag catctggatg taatccaggg gtgggctcat ccgcaataat
    15961 caaagaaacc gtatcactaa tacacgttgt aaacaaaaca cgtcggagca ttccgccaga
    16021 aagttggaaa ggatacaagt caccatcact ttcttttaat ccaaactgtt gaaacaatcc
    16081 ttcttgagta gccttagcat tttctgagat acccaagcgc acctgatgct tgactttcat
    16141 agatggatct aaataattaa cggattgtgg aatcaacgtc atttcttttc ctcgcaactg
    16201 tttgatgcgt ttagaagtta gtgattgacc acgataaatc atatctcctg ttacagctgc
    16261 atttttagga agaatatcca taatagcatg tgctaataaa ctcttgcctg aaccactagc
    16321 acctataata gctaataact cacctttttt aacttctaaa ttcagcgctt ggatcggtgt
    16381 ggattgaaat ggttttaaaa atcttccgta ttgagtgaag gtgatggaga ggtctttaat
    16441 gcttaataat gtttctgtca tatctctacc tcctaaaaat gatccgtttg agggtaaaag
    16501 agtttcttta aagattctcc gatagtatca aaggcattga caaccaaaat aagataaagg
    16561 cctggaaaaa tcaccaacca ccaattgcca agagagatat gcttagctgc ctctgacaaa
    16621 atgataccaa ccgaaggttg ttcggcagaa aggccaaatc ctaagaaagt catggatgct
    16681 tcatgcaaga tgacgtgtgg aaataagagg ataaacccaa tgaaaatttg agaagcaatc
    16741 aaaggtagga tatgatgcct cacaatataa taaggcgttt ttcccatgct tttagagagc
    16801 tggacaaagg ctttattctt tagatcatag acttcattgc ggataagcct tgctagagag
    16861 ggccaatggg taacagctgt tgcaatgata accccttgag cccctttacc aacaacaaaa
    16921 gaaatgagaa tcataaaaat caaatgaggc ataccaataa acaaatcaac caaccaggct
    16981 attattttat caataaggct atttcctaga cctgcaagca ctccaaaaac ggtcgcaaga
    17041 aagactccca taagggcacc taataagccg acttgtaaag agaaataaag ccctttaatc
    17101 gttctgacaa acatatccct acctaaacca tctgtcccaa aaagatggtt taaggaagga
    17161 gcgaggttgc gtaaagctgc attggtttcc aaaggcgtcc tatagaaata aaggtttaag
    17221 gctagaatac taagaatgag agaaatggcg atacctagtt gccataaaac catcgttcga
    17281 cgtttcaata tcatgctttt ctccttaact gtggattgat gatgctattt aaaatgtccg
    17341 caataagatt gcccgcaaaa acaaataatg tccctatcat cacgatagct agaaggagcg
    17401 gtgtatcact tttaagtcct gcttcagtga gggtagaccc taagccagga tatgagaaaa
    17461 cttgctcagc aagaacagat cctccaaaca attctccaaa ataagaaaaa tgcaatgtaa
    17521 tagctggtac gatagcattt ctaagacaat gatgtttaaa aatttgccac tgtgtttccc
    17581 cacgcgctct ggcaaataag acatattcac tagaaagcac cgacatcatt ttagttctcg
    17641 tatgaagggt gacattggca atgcctagaa tacttaacgt gaaaacaggt aacataaggt
    17701 gcttaatccg atcagctaac gtaatatctt gactcaaagt ccctatcggg gaagaaatac
    17761 caatcgggaa ccaccccagc tggacagaaa agattaataa aaaaatgagt ccaatccaaa
    17821 acgttggtac tgatatctga aggtaagaaa accacctgac aactcgatca agtaatttcc
    17881 cttgatggaa agcggataac gttcctaaga taaatccaat aagacccgat aagatccaag
    17941 agagtcccat aagtatgaaa gaagcacctg cccgtgatct aataatatca ctaacaggtt
    18001 gccgataaac gagcgaggtc cctaaatctc cctgtatcac atttttcaac caaataaaat
    18061 attggactag agctggctta tccaagccat agtggtgagc aatcgctttg tactgagcag
    18121 gggttagtga tgtgtcataa ttgacacttg ccatgactgg atctactgga gattgtttta
    18181 acaaaacgaa ggtcaaaaca gataccccaa aaataagcgt gacacatctg atgattttcc
    18241 agatgataat aatggtagta cgtttcacaa tgaaatctcc ttaatcgata agaaaaggag
    18301 ccgaggaaac gatcagcaca gttttgtgta tcttgttttc tcagactcca aacttaaagt
    18361 cgctgtatta actaaacgcg ttacttagtt gattcatccc aagtccactc ggcaatgtta
    18421 gtcaataatg accaatcatg accatgactg tggacgcctt gtttacctac attgatacgt
    18481 ttatcaccaa tataagtatg gttaaggctc accaaccata catttggcaa atctccaaga
    18541 gtagaagcac ctgttttgcc atcccactgc gctaacttcc aatattcgtt agctttgtca
    18601 aggtcagaag atgtcattgc tttgtcaagg tacttagtca cggtaggatt gttataaaac
    18661 gtaatattgg tccaaccttt acctgctagg cttggatgat gtgattcata aaattgctgc
    18721 gcgtgatgac gtcctccggc ataaagtaag gctgagtcat gtgacttcgt tgccatttca
    18781 tcccagttac tagctttgag tttaatagta atccctaggg ctttggcttg ctctgctact
    18841 tcaacggcta agttcgctcg caattgatca ttagtagggt agtacagatc aaacgctgca
    18901 tcaaggtcac cttttttacg gctaccgtct gcttgttctt tccatcccgc ttttgtcaac
    18961 aattgcttag ctttagctac tttattatct ttaatggctg tttttggatt ccaaaatggt
    19021 gttttatcaa taattgaata agctggttta ccataaccat ttaaaaccgt atcgagaact
    19081 ttttgcctat ttaaaccaat agtcaaggct ttgcggattg ctggatcact agtgacatca
    19141 tttcctacag gataaccatc aggagaatca gtgatgacgc cttttttcac ataaggtaat
    19201 gataagccgc gcacatcatt tgatggaatg tcaaggaggc gagtgccttt gactttctta
    19261 ctagcaagtt ctggtgtcgc gtagatcata tcaacatcac cagattctaa agcagctagt
    19321 gctgtgtttt catcaagtaa gacccaagtc cactttttaa agtatggttt tttcccatgc
    19381 caataagggt tacgaacaaa aatagcttgt tctccagcct tatattcttt taccatgtaa
    19441 ggtcctgaac cgataggatt gctcttatac ttatcattgt aatgtttttt agggacgatt
    19501 gggatttcag tcaactgtgc tgtaaatgtc gaatgcgcct cagtcaaatg gatattgacc
    19561 tgatttttcc caactacttc aacgttcttg atgaaggtta gatcccaagc ctttccatct
    19621 gctttcaaca tatcataagt aaacttaaca tcatcagcag taacaggctc accatttgag
    19681 aatttaaaat catcatgcaa gtcaaacgac caagtcagcc catcttcaga gagatggtat
    19741 gttttagcaa gctctccttt tatatctagt tcaggagaac gtttcaatag agtgctatga
    19801 gtgatattcc cttcattgtg gactccataa cggtcctttg gatcgaattc atgagggagc
    19861 tttgccccca tagaaacgac aagttcgtct tttggacgtt gtttgcgctg acgttctttt
    19921 gtttgaggct tttgttgttg acatgcaact aaaataagcc cagtcaaaaa taacgtgata
    19981 atagagaagt attttaggta ttttgacaca a
//
LOCUS       DAUGSW010000027        18239 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUGSW010000027 DAUGSW010000000
VERSION     DAUGSW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18239
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.027"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(40..1206)
                     /locus_tag="VIB18_001195"
     CDS             complement(40..1206)
                     /locus_tag="VIB18_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEQ8766204.1"
                     /translation="MENQLGQLALEQAKTFGGKLEVQPKVDIKTKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEVGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(1238..2569)
                     /locus_tag="VIB18_001196"
     CDS             complement(1238..2569)
                     /locus_tag="VIB18_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEQ8766205.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            2730..4271
                     /locus_tag="VIB18_001197"
     CDS             2730..4271
                     /locus_tag="VIB18_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8766206.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNYLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            4252..4917
                     /locus_tag="VIB18_001198"
     CDS             4252..4917
                     /locus_tag="VIB18_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8766207.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRTQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(4972..6045)
                     /locus_tag="VIB18_001199"
     CDS             complement(4972..6045)
                     /locus_tag="VIB18_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8766208.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(6038..6814)
                     /locus_tag="VIB18_001200"
     CDS             complement(6038..6814)
                     /locus_tag="VIB18_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766209.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGIFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            complement(6811..7605)
                     /locus_tag="VIB18_001201"
     CDS             complement(6811..7605)
                     /locus_tag="VIB18_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766210.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGHVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            complement(7589..8743)
                     /locus_tag="VIB18_001202"
     CDS             complement(7589..8743)
                     /locus_tag="VIB18_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766211.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEEGLINAIEEERNEENF"
     gene            complement(8789..9676)
                     /gene="murB"
                     /locus_tag="VIB18_001203"
     CDS             complement(8789..9676)
                     /gene="murB"
                     /locus_tag="VIB18_001203"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEQ8766212.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPQGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVSDGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            complement(9826..10326)
                     /gene="folK"
                     /locus_tag="VIB18_001204"
     CDS             complement(9826..10326)
                     /gene="folK"
                     /locus_tag="VIB18_001204"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEQ8766213.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            complement(10323..10682)
                     /gene="folB"
                     /locus_tag="VIB18_001205"
     CDS             complement(10323..10682)
                     /gene="folB"
                     /locus_tag="VIB18_001205"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEQ8766214.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            complement(10689..11489)
                     /gene="folP"
                     /locus_tag="VIB18_001206"
     CDS             complement(10689..11489)
                     /gene="folP"
                     /locus_tag="VIB18_001206"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEQ8766215.1"
                     /translation="MKIGRFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSAADEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWIDPGFGFAKSVQQNMELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            complement(11498..12082)
                     /gene="folE"
                     /locus_tag="VIB18_001207"
     CDS             complement(11498..12082)
                     /gene="folE"
                     /locus_tag="VIB18_001207"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEQ8766216.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            complement(12117..13394)
                     /locus_tag="VIB18_001208"
     CDS             complement(12117..13394)
                     /locus_tag="VIB18_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8766217.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYP
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRRYWKKHIEKNVLLTH"
     gene            13722..14684
                     /locus_tag="VIB18_001209"
     CDS             13722..14684
                     /locus_tag="VIB18_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8766218.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEMGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            complement(14801..16036)
                     /locus_tag="VIB18_001210"
     CDS             complement(14801..16036)
                     /locus_tag="VIB18_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8766219.1"
                     /translation="MIKRWAILFFVVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSEPHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDNRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(16194..17381)
                     /locus_tag="VIB18_001211"
                     /pseudo
     CDS             complement(16194..17381)
                     /locus_tag="VIB18_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943304.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(17384..17605)
                     /locus_tag="VIB18_001212"
     CDS             complement(17384..17605)
                     /locus_tag="VIB18_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEQ8766220.1"
                     /translation="MNIGFLEHTARNIIREAKRIAIKKFEEARELEQNAVQLSKSPFD
                     NRRLGIAPKDIVEELVGILLSEESLESEN"
     gene            17692..17835
                     /locus_tag="VIB18_001213"
     CDS             17692..17835
                     /locus_tag="VIB18_001213"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766221.1"
                     /translation="MGISPTGLLRWQPECSEVSLSLFVVMADREPLYFIANNYRSYHG
                     ASH"
     gene            complement(17892..18122)
                     /locus_tag="VIB18_001214"
     CDS             complement(17892..18122)
                     /locus_tag="VIB18_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8766222.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNKKVSP"
BASE COUNT         5726 a         3935 c         3105 g         5473 t
ORIGIN      
        1 tgtgatttaa agtataactt tctctttttt tcatatattc tatgatttaa ggactaccga
       61 cctgacgctt ttagcgacaa tctcagcgac tccttcttta aaggcatctg gaataatatt
      121 agtagtgctc aaagcgtcat ctgggacaag actggcaata ccttttgcgg cagcaatttg
      181 catctcaaca gtaatggttt ttgcccgtgc atctaatgct cccctaaaaa tacctggaaa
      241 ggcaaggaca ttattaatct ggttaggaaa atcactgcgg ccagtaccta caatgtaagc
      301 ccccacttca agggcttcat cagggtaaat ctctggaata gggttggcca tggcaaaaat
      361 tactgggcgc gctgccattt tactaatcca ctctgctttt aagactcctg gtgctgatac
      421 gccaatgaag atatctgctc cttcaagagc atcttctaag gtacctgatt taaactcacg
      481 attagtgact ttcgctatat ccaaatgatg tggcgctaat tgagcggctt cttgttcatt
      541 gataatgcca aatttatcca ctactgtcac tttcgtagca cctgctgcta ataatttacg
      601 ggtaatggat aatccagcag atccaccacc gttcaccaca atggatacct catcaaggga
      661 ttttttaaga agtttcaaac tattgaagat ggctgctaac accacaatag ctgttccatg
      721 ctgatcgtca tggaaaacag gaatatgaca ttccttaatc aagcgctgct caatttcaaa
      781 acagcggggc gcactaatat cctctaaatt aataccacca aaggttggtg caagcgcctt
      841 gacaatacta ataatttctt cagtatcttt ggtatctaat acaatcggaa tagcatcaac
      901 acccgcaaat gctttaaaaa gggctgcttt tccttccata actggcatgg ctgcttcagg
      961 gccaatatcc cccagaccaa gaaccgcagt accatcactg ataacggcta ctgtattttt
     1021 cttggtggtt aagtcatatg ctaatgtttt atcttttgcg atggcagatg acacactcgc
     1081 tacacctggt gtataggcaa tgctcaaatc atgtttagtt ttaatgtcaa cttttggttg
     1141 aacttccaat ttaccgccga acgttttggc ttgttcaagg gcaagttgac ctaattgatt
     1201 ttccataggg aatacctctc ttttttattg gtttggatta actaaaaata attcttaaaa
     1261 tagctgtcat agtgataacg gtaatagccc cacctagacg ggtagcgact tgggcaaacg
     1321 gcattagatt catgcggtca gccgtactca aaatagccac atcaccggtt ccacccatac
     1381 cactttgaca agctgaaata atagctgctt ccactgggtt catgttaagg aaacgagaga
     1441 caaaaaaacc gacactgaca accgttaaca ccacactaat caccacaata aaatattgcc
     1501 agctaagggt tgccacaacc tcttttaagg ggatataaag tagaccaagc cctgccatta
     1561 acggaaaagt aaagttgctg gaaatgaatt tataaagttg cttggcacca ttttgggttt
     1621 cttggggaat aacattcagg tatttcaaga aggctgccag aataatcatc aacaccggtc
     1681 ctggaaaacc tgttaaatgc tgtaacaagc caccagcaat aaaaagtgaa caagctgtta
     1741 aaacgcctgc ccccattaat ttaacatcta gggctccaga attgtctttt agggcatcag
     1801 acatgtcttc gctgtgacca attttaacca gttgcccttg accagaataa cttgggtgct
     1861 tctctccaaa acgattgagc aaagccgtgc acaagatagc aaagaaattc ccaataatgg
     1921 tggctggaat cagttgagcc actaattgct cacttccgac tcctgtaatg gcactgtaac
     1981 caagagataa gggtaaaata ccttcaccaa ttcctccagc aaggactggc gtcacaacat
     2041 aaaagagggt atgttgccag tctaatccta aaatgacgcc aaccaaagtc cctacaccca
     2101 ttgcacaaac cattccaagt aacatgggaa taatcatccg aaaaagacct tgaatcaaga
     2161 tttttcgatt catgcctaaa atactaccgc agaccaggca ggcaatataa aaataaagaa
     2221 aattggcttg cttcatcaag acattcgtcg cttctaagac attgggattg aggagattaa
     2281 aaaaaaccaa aatcgaaggg actaagagtg ataaaatagc tgggccacca aaatgtttga
     2341 ggcctggaat ggtcgctcca atggttccta gtagccaacc aagggttaaa ataacagcaa
     2401 agccacccag catattaaca ggcaattgtt ggagccagcc tgtgactaaa attaaggtag
     2461 ctaaaaccag ataaacaggc aagggaacgg agcctattcg cctattttgc catgcttttg
     2521 aatgctcaga caagtctttt tgaggcattt tcttgcttat tgtttccatg aaacaacctc
     2581 ctttagtgat aaggctagta taaaagagaa catgtcaaaa gcatagttta tttaagttgt
     2641 ttaactactt taattttttc aagttattta attaatttaa gctagcaggt catttcttat
     2701 cgtgttatac tcaataaaga ggagacctta tgaaaaaacc actacgttta tgggccagtt
     2761 tatcgttgat tttggtatct atgattgttg tcacaacctc tctattttac gggattatgc
     2821 tacatgatac gcaccaatcc atcaaaaatc aggaaaccca tttgctaacg tcaactggaa
     2881 aaatgttagc aagtcatcaa gcgattaaag aattactcct aaacaaccaa ccaaatgcta
     2941 aaacaacagc ctataccaac tccattgcct ccatctataa ccttgattat gtggtcgtga
     3001 tgaacatgaa agggattcga ctcacccatc ctaacccgaa aaatatcgga aaaccttttc
     3061 aaggaggtga tgaggaggct gttctagcag gaaaaaaggt tatctctacc gccaagggca
     3121 ctttaggaaa gtcacttcgc tatctagtac ctgtgtttga cggtgacaaa cagattggtg
     3181 ctattgcggt tggcattaaa ctaactaccc taaatgatgt ggctttaacg tcaaaacgca
     3241 attataccct gtctttactc ctttgtcttc ttattagttt actggtcacc agttttattt
     3301 cttttcgact caagcgtcaa ctgcaccagt tagaaccaag tgaaatttat cagctctttg
     3361 aagagcgtaa tgccatgttg gatcaaatcg aagccgccgt atttgtggta gataaagctg
     3421 gtatcttaca gctctgcaat caggctggac aaaaattaat tgctcggaaa tgccagttgg
     3481 gaaaacctac tggcaacagt ttcaattacc tctttcctga ttttccaaaa cttagtttgc
     3541 aagaggggca tgaacaactc tttcggtatg gtgaggaaga ctacttgtta gccatttcac
     3601 ccatctgtgt caaaaacgat caccgaggcc acattatttt catgcgagaa gcagttaagg
     3661 ctattgatac cttggatcag ctagcctata ccactgccta tgcttctgct ctacaagccc
     3721 aaactcataa attcatgaat caattgcatg ttatttatgg cttagtggat attgcttatt
     3781 atgaccaatt gaaaatttat ttagacagta ttttggaacc cgaaaatgaa attctcacta
     3841 gcttatctgt ccttgttaag gagcctcttc tagctagttt tctcattgga gagcaagaga
     3901 aataccaaga attaaatgtc catctcaaga ttgatgtttt aagcgagatt cctcattctg
     3961 ccaccaagaa tcaacttaat aatggtttga tgatttaccg ctttatccat actaatcttc
     4021 taaccacact gagacccaaa tcactcgttt tgagtattca acatgaccag aatcatttaa
     4081 tcagccatta caccttgaca gacaattgga ttgatttgga gcgggtacag cctatttttg
     4141 acttacctta ttttcaacag ctcttgaccg atacaaattc ccaattccat caacatcaaa
     4201 ccgtaaccga gttacagttc tcagtgacaa caccttatgt aggagggcaa catgaacgtt
     4261 ttaatcattg aagatgatcc tatggtggat tttatccatc gcaattacct cgaaaaacta
     4321 aatctttttg atcgcattat atccagcgac tctatgaaag ctgttcaaag catacttact
     4381 gattacgcaa ttgacctcat tttactggat attcatatta cagatggcaa tgggattcaa
     4441 tttttggaga aatggcgtac tcagcatatt ccttgcgaag tcattattat ttcagccgca
     4501 aatgatggga atattatccg agatggtttt catttaggaa ttatcgacta cctcatcaag
     4561 ccctttacct ttgaacgctt tcaagaaagc atccaacagt ttgttacaca tcgagaacat
     4621 ttggccaatc agcaactaga gcaggcccaa attgaccaac tgaaatgttt gactagcaaa
     4681 aaagacacta aaaacaaaca attgttagaa aaaggcttat ctgaatccac tttccagtgg
     4741 attatggaaa atatcaaagc ctttgatcaa ccttttacta tccaagaatt agcttccgct
     4801 tgtcacttat cccatgtctc tgtccgtaaa tacattgctt atttagaaga aaataagcag
     4861 ctgaacagcc aacaaatttt tacaaaggtt ggccgcccct atcgcgtgta ctggtgacgt
     4921 cacctgtcga tacattaaaa aggctggaga aataccagcc tttttgagtg cttatttgcg
     4981 atacatttta aattggaggt ataaatcatt ataaatcccc aaccatcttg accctaaatt
     5041 gtcataaact tccaattttt tgataatgtc atctgttgga taaaaagcag gatcattttt
     5101 tatctcatct ggaagtaagg ccttggcttt tttatttggt gtcgcataac caatatatgc
     5161 agcattttgc gcagcatttt caggacgatt gataaagttc aaaaaagcat aagcttcttt
     5221 ttcgtgtttc atggtttttg gtagtaccaa attatcaaac caaaggttag acccttctga
     5281 aggcacgatg tagtgaaggt gttcgttact atctaacatc tcactggctt caccagaaaa
     5341 ggtaattcca atagcagcgt caccttgaat catgtagcct ttcatctcat ctgctacaat
     5401 ggctttaaca ttcggcgtca actgctgcag ttttctctcg gctgcctgca actgctctag
     5461 atttttagaa ttcacactat aaccaaaagt tgttaaacca acccctagca tttcacgcgc
     5521 tccatcaatc agcataatac tatttttata ttctggacgc cacagatctt cccagtgcat
     5581 aggcgcctta tcaactaatt gatcattata aacaatccca acggttcccc agaaataagg
     5641 caaagaatag tcgttttgtg ggtcaaagct tttccctaaa aattctttcc cgatattatc
     5701 catgccaact aattttgact tatcaagctt attgagtagg ttttctttga tcattttatc
     5761 aatggtgtaa tcactaggaa cagcaatgtc gtaagtggtt ccgccctgct tgattttagt
     5821 gtacatggct tcattggaat cgaaagtttc atactgcact tcaatgcccg tttctttggt
     5881 gaattttttg agcaaagctg gatcaatgta atctccccag ttataaataa ctaatttatc
     5941 cgattgacta ccagaacccg attttttctg caagatgaaa gaaagacttg ttaaaataac
     6001 aataacaccc aaaactcctg ctagaaagga ataaagttta cgcatgtttt tcctccttgt
     6061 cctgtgacat ataataataa ccgatcacta agaggatgga gaaaaagaaa acgatggttg
     6121 acaaagcatt gatatccaag gaaattccct gacgagcccg cgaataaatc tcaacagata
     6181 aagtagtaaa accatttcca gtcaaaaaga aagtcactgc aaaatcatct aaggaatagg
     6241 taaaggccat aaaataacct gcaataatcc ctggtgttaa gtatggcagc atgacttctt
     6301 tgagcatttg gaaataatta gctcccaaat cataagcggc gttgaccatg tcctgattca
     6361 tctctttcaa gcgcggcaat accatcaaaa ccacaatagg aatcgaaaaa gcaatatgac
     6421 ttaataaaac tgaagacatg cccagctgaa acttcaatga tgtaaaaaga attaaaaagg
     6481 aagccccaat catgacatct ggtgatacca tcaagacatt attggctgat agcatggcat
     6541 tttggtactt acctctaaca tggtggataa agatagctcc aaagatccca ataatcgttg
     6601 ctagtagagc gctactaaaa gcaagaacaa aggtttgcag taagattgtc atgagacgac
     6661 tatcctcaaa catggtttgg taatgctcaa gggtaaatcc tgtaaaacca ttcatatccc
     6721 cacctttgtt gaaagaatag aaaatcaaat aaaaaatagg aatgtagagt aaaacaaaga
     6781 cactcgctaa ataaagattg gcaaattttt tcatttactt ttctcctttg tgagccacat
     6841 aatagcaacc atggtcaaaa tcaagacgac accaatggtt gatcccattc cccagttttg
     6901 ggtggtcaaa aaatgttgtt caatggctgt accaagtgta atcacccggt ttccaccaat
     6961 caaacgggtt aacataaaga gactcaaact tgggataaag acagactgaa cacctgccct
     7021 aaccccattt aaagaaaggg gaaaaataac ttttgagaag gcctgaaatt cactagctcc
     7081 taggtcgcga ctggcattga tgacattatg gtcaatatca tccaaagcgt taaaaatcgg
     7141 taacatcata aaagggagct caatgtaaga ggctacaaaa atgaaggaga aatccgtgaa
     7201 aaggatttgc tgcgggccaa tccccataaa ggttaaaaag ctgttaatcc ctccttgttg
     7261 accaaagatt cccataaagg cataggcctt tagcaataaa tttacccagg ttggcaagat
     7321 aatgagcata agccacaact gcttgtgctt taggcgcgtt aaaaagagag ccgtaggata
     7381 tgaaatcaag agcgtgacga gtgtgataat accagcgtat aaaatagaat tcacactcat
     7441 tctcaaataa gtccaagagc taaaaaacgt ttcgtaattg gctaaagtca catgcccttc
     7501 aatgtcaaaa aaggacttgt aaaacaagag agtgactggt gccacaacaa agaagagaat
     7561 ccataagaag taaggaatcg aaaaaagact agaagttttc ttcattacgc tcctcctcaa
     7621 tggcattaat caatccctct tcaggctcat ccatttccac atattcttca atacgggcat
     7681 caaattcctc ttcagtctca ttaagacgca tgatatgaag atcttcaggg gtaaaatcta
     7741 atccgataac ttctccctcg atagctttgc gggtagaatg aatcatccat tcattaccca
     7801 attcatcata ggcaataatt tcgtagtgaa ccccgcggaa taattgggta tcaaccttaa
     7861 cttgtaattt cccttcttct ggcaaagtaa tttgaagatc ttcaggacga ataaccactt
     7921 caacaggctc attagggcgc attccaccgt ccacagattc aaattctttc ccgttaaagg
     7981 agacaagata gtcttcaatc atggtaccgt taataatatt agattctcca ataaaattag
     8041 caacaaaatg attaattggc tcatcgtaaa tatccactgg tgttcccgac tgaacaattt
     8101 caccttcatt catgacaaaa atccaatcac tcatggccaa ggcttcttct tgatcgtgag
     8161 taacaaaaac aaaggtaatg cctagacgtt gttgcaattc acgtaattca tattgcatct
     8221 ctgttcttaa tttcaaatca agggctgaga gtggttcgtc aagtaagacc acacgcggtt
     8281 gattgataat cgcacgcgca atggcaacac gttgacgttg accaccagat aacttctgga
     8341 tagaacgatt ttcataccct tctaattgaa ccattttcaa ggtttctttc acgcgcttag
     8401 caatctcttt cttgtccact ttcttcagct tcaaagcaaa ggcaacattc tcaaaaacag
     8461 tcatatgagg gaagagggca taattttgga aaacggtatg aatgtcacgt ttattaatcg
     8521 gcaaatcatt aatacgttcc ccatctaaat aaatgtctcc gctgctggca tctagtaggc
     8581 ccgccataat atttaaaata gttgattttc cagagccaga agctccaagc agggtgtaaa
     8641 attttccttc ttcaaggtca aagttaatgt tctttagaac ctgtgttcca ctgtcctcaa
     8701 atgtttttga aacattgtta aatgtgataa ttggcttagt caattgtcat aaatcctcca
     8761 cggtactttc tttaattatc aataatggtt acaggttttc cccaataatc cgaacttctg
     8821 gttcaagcct gacaccagaa tggttttcaa ctgtctcaat gacataagca atcaaatctt
     8881 cataatcttt agctgtgcca tctgacacat taatcataaa accagcgtgt ttttcggaaa
     8941 cttccacacc accaatccga tgccctttaa gatttgcttc catgattaat tgacctgcaa
     9001 agtgtccttg cgggcgctta aacacagatc cacaagatgg aaattctaaa ggttgtttta
     9061 gttggcgaag gtgatttaac cgattcattt cttggctgat cgtatcataa ttacccggtt
     9121 taagagcaaa cttagcagaa atgacaatgt cacctgtttc ttgaatggca gagtgacggt
     9181 aaccaaaagc catatcccta gctgaaatgg ttttgatctc tccacttgag gtaagcacct
     9241 tagcggataa gaaaatatgt gatatttccc caccataagc acccgcattc ataaaaacag
     9301 cacccccaat gcttccagga atgccacatg caaattcaaa ccctgttaaa ctatggaatt
     9361 tggcaatctt cgttgtttca atcagattgg caccagcttc agcttctaag gtataaccat
     9421 ttaagtgcac tgcatttagc ttatcaaaca tgatgacaaa gccacgaata ccaccatctc
     9481 gcacaatgag attgctggca tttcccaaaa caagccaagg catattttct ttgttggcat
     9541 aagcaacgat gcgtgatagc tcgtagtgat ttctaggaaa agccaagaaa tctgctgggc
     9601 cacctacctt agtgtaagtg taatgtttta ggggttcatt ctctcgaata tcaatcccat
     9661 gaagttcagt tatcatagtt atcttctttc ttttatcact tcttatacgc gtaaaaaaat
     9721 cggcataaag ccgatactat tatatcaaat tttagaaaaa ataacgatga atttggcaaa
     9781 actttatgga ttggcttata gcaggcatta ctccgaaaac agagtctaga actctgtctg
     9841 ttgagctgaa aagagcgtga tatctgattg atctaaagct gcaagataat cccttaaaaa
     9901 cttatgatta ggaggcaatt ttaaatctgg ctgcaattcc aataagggga ttaaaacaaa
     9961 agcacgctca gtcatataag ggtgtggcac tttcaattcc tttgtgtcat aaacctcttc
    10021 tccaaatagc aagatatcaa tgtcaatagt tcttgatccc catttttcat gcctcacacg
    10081 accaagagat tgctcaatag cttgtgtttc ttttaagaaa tcagccgcgg ttaattgtgt
    10141 atctaattga caggccatat tgagaaaatc agcctggcct gtcttgcccc aagcagtcgt
    10201 ttcataaatg gatgattgag caagcaaccg tgtttgaggt aagtcagcta aagcctcaag
    10261 agctttttgc aagtaagctg ctcggtcccc catattggtg cctaaactta aataaacaat
    10321 ggtcatctct gtctctccaa ttcaatacca actgccttat agtggcctgc aatcggtggg
    10381 ttttcctttt taatggccac tttgatggct tcaataggcg gaaattcgtt aaaaagctgt
    10441 tcacaaatcg cacctgctaa acgttcaatc aaaataaact tttccccttc cactaactga
    10501 cggacactgt caaacaccat cccgtaatgg accgtatctg ttaattggtc tgacaaagaa
    10561 gctgcttgca aatcgactga caattctaaa tcaaccagaa aaatttgccc aagggtctgt
    10621 tcttctttaa aggctccatg gtagccataa aaacggcaac cttctaatac gattttatcc
    10681 ataagtcttc acatcaactg gctcaacaca gccacaatgt cttgattagc cttgacatcg
    10741 tgtacgcgta caatctgaca gccttttcca agggcataag cagacaaggc tgctgtcgct
    10801 ccgtctcgct ctttagcttt ggtgttgccg cctaacaagg catctacgac acgctttctc
    10861 gaaataccaa acaagacagg atagcccaac tgacagacgc ggtccaatcc ttttaataac
    10921 tccatattct gttgaacaga tttggcaaat ccaaatcctg gatcaatcca aatattgttt
    10981 tttggcacgc cagcatcaag agctgcttgt gctctattgc ctagaaaatc acaaacgtct
    11041 tgtgttacct cttgataaac ttcttcgtct tggttatgca tcaagatgat aggcgcatcg
    11101 tactcggctg ctaaggcaaa catttgtccg tcgtacaaac ctgcccaaac atcattgaga
    11161 atatcggcac ccgcctctaa agctgctcta gctgtttcgg ttttataggt atcaatgctg
    11221 attagaatat catagttttc tttgatagcc ttgatcacag gaaccacccg gtcaatttca
    11281 tcggcagcgc ttacaaattg gcaacctgga cgtgttgatt ctccaccaac gtcgatgatt
    11341 ttagcaccat cagcaatcat ttgctcaacg tgatctaatg ctttttgcac agtagtgtaa
    11401 gaccccccat ctgaaaaaga atctggagtc acatttaaaa tccccatgat agccgcattg
    11461 ccctcaatca caaaccttcc aattttcata agtcctccta atcttttgtc attagagaaa
    11521 taacttcttg cctctcagca cgactttcct tgtataagcc tctggcagtg gtggtaatgg
    11581 ttttactacc tggctttttg atgcctcgca tggtcatgca catgtgctct gcttctacca
    11641 taactaaagt ccctttagga ttgagggctt caactaaagc atccgctatt tgagaggtca
    11701 aacgctcttg gagttgaggt cgtttactag ctacttcaac tgctcgcgct aatttactca
    11761 aacctgttac tcgaccatca cttggtaagt aagcgatatg agccttgcca taaaaaggaa
    11821 ctaagtggtg ttcacatata gaataaaaac taatgtcttt gacaatcacc acatcctcat
    11881 gttgttcttt aaagacagcc gtaaactcct ctttaggatc ttttcccagt cccaaaaaca
    11941 tctccgcata cattttagca acccgtttag gcgtgtcaag aagaccttcc cgatttggat
    12001 tttcaccaat agcctctaaa aactgataaa tggctgcttc tgctttttcc ttattaatag
    12061 acattagtct ttcccttttc attagttttt tccttttcct tttcattttc tcttttttaa
    12121 tgggttaaaa gaacgttttt ttcaatatgt tttttccaat accgtctaat ttctgaaata
    12181 aaatatagtg accctgtaat cacgaaaaag tcatctgctt tagcatgctt acgcagggcc
    12241 aagaaatctt tgaaatcagc aaccctacca aaacgttctg ggtatttttc caatggatag
    12301 gcgttagggt aatgaaagcc agtaacctgc aagtcaccta tttgctcaag agcaaccaac
    12361 atatccgcaa taggcttggt gtcgatcgca ccaaacaaaa tatgaagctt tttatcattg
    12421 tagttatttt ttaagacggc taccaaagca gcaacgcttt cattgttatg agccccatca
    12481 atcattagat ttggtgctaa taattcggta cggcctagcc acaaactatt tgccagacct
    12541 tcccttatat gatctgaagt tagcctagga tagcggtctt tcaaggttaa gcaagtcata
    12601 atagctaaag ctgcattaga cacttggtgg tgtcctggca tagcgatgtg aatatctgaa
    12661 ataactccta aaggactagt aaaacgatag ccagatgcgt tctcagccat ttgaaactgc
    12721 tcttgccatt cccagattga agcaccaacc tgctcagctt ttgttaaaaa aacctctcga
    12781 gctgacgggt tttcaacggc aaaaacaagg gtctcgcccc cttctaaaac accagctttt
    12841 tgggcggcaa tatcagcgta agtctctccc aaaatagctt ggtgatctaa accaattgag
    12901 ggacatacca caaccattgc ttgaaaaaca ttggtcgaat cataaagacc gccaaggcct
    12961 gcttcaataa tagcaatatc tacaggatgc atgtctccaa aatagaggaa catgatcaaa
    13021 gtaatcactt caaattcagt tacctctcca aaatcagtct cttgaactag acgctctgtc
    13081 aaaggacgaa tacgattagc agcaataacc aaatcttttt ctgaaatcat tcgaccattt
    13141 atgctaatac gttctttgaa atccataatg taaggagagg taaaggtccc cacttcataa
    13201 ccagctgtcg taaagatatg ttgtaaatga ttgaccgtgg aaccttttcc gttagttcca
    13261 acgatatgca ctcccttgac atttttttgg ggatttccta actgtccaag aacccaaagc
    13321 atacgtttta agcctggctt gatgccgaaa actaagtgat catgaatcca ttctagagtc
    13381 tcttcataag tcatttcata cctcacatct atctttagta taccatatat aaaaaaaagt
    13441 gacagcagat aacctagagt agtacccttt ttttatcctc accaaacact caaataagtt
    13501 ctaaagtaca ctacactttt atcttcattg ctttttttac gtgataagaa taccagcccc
    13561 acatagtctt tgctacctcc taaagtgtta tctgtgacaa caattttttt actccttaat
    13621 acacgttctt ccaaaaaaca agaaaaaagg ctgacttcaa gccttctttt ctctaaaaaa
    13681 tgttacaata gaggtactta tatcaaaaaa aggagcaagt aatgaacaat agacataaac
    13741 ggcgccaaaa aagaaaagcc ttcactctca ttaaccttat actattattt gcctgcattc
    13801 ttggtttgac cctcattttc tatttatatc aagggtctaa caaattcggc ttgtcagatg
    13861 tctctcaatt tgtacctaaa ataagtcttt ttcatcacaa aaagacggca aaaaaagaaa
    13921 cgacaaaact taagaagact catttcgatt cctcaaaatc tcaaaaaaag gcccattcta
    13981 aattaacttg gaccaagcaa gaaacacctg tcaagatccc aattttaatg tatcatgcta
    14041 ttcatgtaat gtcccctgaa gagacggcca atgctaattt gattgtcaac ccagatctct
    14101 ttgatcaaca acttcaaaaa atgaaagacg agggctacta ttttttgagt ccggaagagg
    14161 tctaccgcgc tctttcaaat aatgaattgc ctgctaaaaa agttgtatgg ctaacatttg
    14221 atgacagtat gattgatttc tacaacgttg cttacccaat cttaaaaaaa tatgatgcta
    14281 aagccaccaa taatgttatt acaggactaa ccgaaatggg aagcgctgcc aatctgactc
    14341 ttaagcagat gaaagaaatg aaacaattcg gtatgtcttt ccaagatcat acagtgaatc
    14401 atcctgatct agagcaggct agtcctgatg ttcaaacaac tgaaatgaaa gattcaaagg
    14461 actatcttga taagcaatta aaccaaaaca ctattgccat tgcttatcca tctggtagat
    14521 ataatgacac taccttacaa attgcagcta gacttaacta taaattaggt gttaccacta
    14581 acgaaggaat agctagcgcg gctaatggac ttctttctct taaccggatt cgtatcctcc
    14641 caaacatgag tccggaaaat cttttacaaa caatggaacc ataacatcaa tttttttatc
    14701 attccaaatc atactcaccg taaactaaaa agacagttat gaaaaaattc tttcataact
    14761 gtcttttttt gattgtttta aaattatttt attcttatct ttaacgtctt ttttcaagaa
    14821 aatctcgcca ccacagctgt aagtcagagg cttttttaag agattggcta gctttaagag
    14881 gaatacgctt aggttccttt aaatacctca ctgactgatc tgttattctt ggagacgtca
    14941 aataagcaac cacttcacct ttagtaatcg gtgctagtaa agaagtctct gatatcataa
    15001 attgtttagg tttgggaact tgttcaccct gttgcaaaat gatggttaca tcttcggcaa
    15061 cagataccgg tagttctttt acttggccat cttgaatagg gagcgaccgc tccgagacaa
    15121 gacttccttt tttaagaatc ttacgacgac aataagttct agccacatag tccaacaaac
    15181 gatttgcttg ctcaaaccgc gtgttttggt ttttatcaga tccatcggca tttagaataa
    15241 cggtaatcac tcgcatacca ttttcaatag aagttaccac aagacaatga cctgccaagt
    15301 ctgttgtccc agtctttaaa ccatccactc ctgctctacc cttagccata cctggtaaga
    15361 gttgattaaa acttttaata gaattgccag caaaattaac ttctgtttgt ttggtgatct
    15421 ctaaaatctc aggaaaatct tctaacaaat gcatcgtcac aactgcaaca tcttgagcac
    15481 tcaaggtatt ttcttcttcc aacgcagaac caggataacg attatccttt aacacctcat
    15541 ttggcagacc tgaggcgttg aggattttac cagaagtaat cccccaatga gatagctgtt
    15601 ctctcatttg atttacaaaa tgaggctctg agcccgccac tttttcggcc aacgcaatag
    15661 cagcgctatt tgagcttgct accaaagtag ctgtcaacag gtcttgaact gaataagttt
    15721 ttttgtcaaa aggtacatta cttaaagacc tatcttttgt taactcgaag gcataatctg
    15781 agagattaac ttgatctgat aattgcagct ggcctgattt aaccttatct aaaaccagat
    15841 aagccgtcac caatttggtc aaagaggcaa tagcatctgg cgtcttagcg tctttctcat
    15901 acagaactct cccagagtct gcctctacga caatcgcatg ttctgctccc acttgaaaat
    15961 cagctgcgag aactgtttta ccaaaccctg aacaagttaa taccacaaaa aaaaggatag
    16021 cccacctttt tatcattata tctttcatag ttactattat aacaaaaatt ctcagaaatt
    16081 tggaaggaag tatagtggca cacaccttta gtagcttaaa caagctcata aagcaagtac
    16141 cctgtaacaa taacacatcc tgttatatgg gcgatataat aagcttcgtt atatcaatta
    16201 gttgtttggc aggaattttg gtataaaatg gaatctaatc ctgaacttat tacattttgg
    16261 gttatttctt cagatactgt tttatctaat gcgttaaatc agtgactata tgtattcaaa
    16321 gttgtagact tatcagcatg tcccatacac tttgcaacat acagaatgtc ttttttcaaa
    16381 acattaataa gataggaagc atgactatgt cgcaatcctt ttccagttat tacgggaact
    16441 ccaatacttt gagctttacg cttaataact cgacaaatcg ttgatttaca aaacggttca
    16501 ccaaatcgtg aaataatgaa atctgtgtca gtattgacta cttgatttct tctccaattt
    16561 tccaatacta ctattgtcac atcatctaac tcaataagac gttctcctgc tggcgttttt
    16621 gtttggtctt tacgatacca atttccattt tcatcctttt ccaaggttgt atgaactttc
    16681 aaaaattttt gttcgaaatc gatatcttcc catcataatg ataaaccttc acttacacga
    16741 acacctgtca tataatatag ccaaatagtt gtaaatcttt gtagctcttc ataatcttgc
    16801 aaatcaaacg attttataaa attctgaaac tcaatataag tccaaaatgg agtatcggga
    16861 tgtttccctt taggattatc caaagcctta cacggcactt ttgaaatata gtctaacctt
    16921 tcagcatacc ccatgcaagc tttgaatcgc gaccataaat tctttgcata attttcaata
    16981 atatgtaaac taaaagattc acaatctcaa gctgttattc cctttaaaag tttagaacca
    17041 aaatactgaa taaataactt atgatgtggt aaggctattt cataagttac agcctgaacc
    17101 ttttgcttat atgctcttag gtaaatagta ttcatatagt tttcaaacga tatattgtca
    17161 ttttcaatac taagattatt actaaactca tacctaatcc gaaccagttc atcatacgct
    17221 tctttcattg taccaaatgg ctttccatac taattctttc tggctttctt ttgaactcgt
    17281 ttacctgtta ctggatctac accaagatca gcttgataaa atatcttacc attcttatca
    17341 caataaacac ctttgtactt tttttgattt tttatagtca tctttaattc tcactttcta
    17401 aactttcttc agagagtaga atacctacta actcttctac aatatcttta ggagcaatac
    17461 caagtcttct attgtcaaag ggcgatttac ttaattgtac cgcattttgt tcaagttcgc
    17521 gagcttcttc aaactttttt atagctattc tttttgcttc tctaataata tttcttgcag
    17581 tatgttcgag aaaaccaata ttcatcaagc tttttatatg ttactatttt cacacctcca
    17641 ctcctttcaa aaaaattaca acctccgtgg gtatgactgg ttaaatcact catgggaatc
    17701 tcacccactg gccttttacg ctggcagcct gaatgttcag aagtatcatt gtccctattt
    17761 gtggtcatgg cagatagaga accactctat tttatagcta ataattatcg ctcctatcac
    17821 ggcgcatctc actaaattgc tcgacaaaca agaaagtccc acctcggttt attcagttgt
    17881 caatgaataa atcaaggcga gactttttta ttatgaaaac gatacggata atctgtttgc
    17941 cctaataaat aatcaatact gacgttatag agtttagaaa actgcacaag aacatctgcc
    18001 attaaggcaa cctctcctct ctcaattttt gcataatttg catgagagaa ggaaagtaaa
    18061 tttgcaacaa acttttgagt gaaatcgtta tcttctctca aattcctaat acgcgggtac
    18121 atctaacatt ctcctaatat cagtataaag gagatttgat taaaaaatgt ttaattgtcc
    18181 tatttggaca agtctattaa atataagcta gtaaaccatt gaaattttat agtcatttt
//
LOCUS       DAUGSW010000028        18229 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUGSW010000028 DAUGSW010000000
VERSION     DAUGSW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18229
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.028"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..542)
                     /locus_tag="VIB18_001215"
     CDS             complement(<1..542)
                     /locus_tag="VIB18_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEQ8766223.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKP"
     gene            634..981
                     /gene="ssrA"
                     /locus_tag="VIB18_001216"
     tmRNA           634..981
                     /gene="ssrA"
                     /locus_tag="VIB18_001216"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            1283..1903
                     /locus_tag="VIB18_001217"
     CDS             1283..1903
                     /locus_tag="VIB18_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEQ8766224.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(2160..4424)
                     /gene="glgP"
                     /locus_tag="VIB18_001218"
     CDS             complement(2160..4424)
                     /gene="glgP"
                     /locus_tag="VIB18_001218"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEQ8766225.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHDFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKYIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLVFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(4459..5952)
                     /gene="malQ"
                     /locus_tag="VIB18_001219"
     CDS             complement(4459..5952)
                     /gene="malQ"
                     /locus_tag="VIB18_001219"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEQ8766226.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(6067..7086)
                     /locus_tag="VIB18_001220"
     CDS             complement(6067..7086)
                     /locus_tag="VIB18_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8766227.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            7331..8578
                     /locus_tag="VIB18_001221"
     CDS             7331..8578
                     /locus_tag="VIB18_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8766228.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALIGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLNQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            8852..10213
                     /locus_tag="VIB18_001222"
     CDS             8852..10213
                     /locus_tag="VIB18_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8766229.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAILDLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            10213..11049
                     /locus_tag="VIB18_001223"
     CDS             10213..11049
                     /locus_tag="VIB18_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8766230.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            11230..12058
                     /locus_tag="VIB18_001224"
                     /pseudo
     CDS             11230..12058
                     /locus_tag="VIB18_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_037603748.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12572..13555)
                     /locus_tag="VIB18_001225"
     CDS             complement(12572..13555)
                     /locus_tag="VIB18_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8766231.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTALQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFQIREAKQARKQIAELVLKTVEHT"
     gene            complement(13586..14836)
                     /gene="dltD"
                     /locus_tag="VIB18_001226"
     CDS             complement(13586..14836)
                     /gene="dltD"
                     /locus_tag="VIB18_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEQ8766232.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNFYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(14829..15068)
                     /gene="dltC"
                     /locus_tag="VIB18_001227"
     CDS             complement(14829..15068)
                     /gene="dltC"
                     /locus_tag="VIB18_001227"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEQ8766233.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(15086..16342)
                     /gene="dltB"
                     /locus_tag="VIB18_001228"
     CDS             complement(15086..16342)
                     /gene="dltB"
                     /locus_tag="VIB18_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEQ8766234.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSRTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(16339..17877)
                     /gene="dltA"
                     /locus_tag="VIB18_001229"
     CDS             complement(16339..17877)
                     /gene="dltA"
                     /locus_tag="VIB18_001229"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEQ8766235.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(17889..18032)
                     /locus_tag="VIB18_001230"
     CDS             complement(17889..18032)
                     /locus_tag="VIB18_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEQ8766236.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT         5875 a         3553 c         3070 g         5731 t
ORIGIN      
        1 ggtttagtta ttaaaagaat agttacaaag cgctttaaag acatgtccgt caatcccgta
       61 atcataacca taatatcagc tggagaaaca ggcgatgcca tacaaaaaat aaataatttt
      121 tcatatcctg gtgtctccaa acgcctttca tacttgtaaa atgttttgtc atttacaaag
      181 agtaagataa atttacgacc ataagtctta acaagcaaga agaggactat actgccaata
      241 atgatgccta cataattata aataaaacct gttacagggc caaagattaa aaaacctgca
      301 actgtcgtaa ggcctccagg aatcacagga aaaacaatct gtatgatctg cacgacaata
      361 aaaacaaacg gcccccataa tctatagcgc tgcactaagt ctttaagagc attactatcg
      421 tttaatatac ctagtctata cagccaaaaa gcgaggaaaa aagtaccaat tagtgcaata
      481 attcctaaaa ttttgataat tttttgccat aatatatagg cttttgaatt acgttttgtc
      541 atagactaat cataccataa gctgtaaaat tttgctattt aaaaaaagtt ttgatagaat
      601 agttagtgta agaaattggt taattatcta tttggggttg ttacggattc gacaggcatt
      661 atgaggcatg ttttgcgtct catcggcaga tgtaaattgc cagttaaata taactgcaaa
      721 aaatacaaac tcttacgctt tagctgccta aaaaccagct agcgtgactt ctacaagatt
      781 gcttgtgtcc tgttagaagt ctcaaaatag caagctacgg ttacgaaatt gtctagtttc
      841 gtgacaagag attgatagac tcgcaaacta atggcttgag ttatgtgtct ttagtttgtt
      901 aaatgaagac ataacctatg gacgtagaca aatatgttgg caggtgtttg gacgtgggtt
      961 cgactcccac cagctccatc aatgcttacc gtaagtaatc ataacttact aaaaccttgt
     1021 tacatcaagg ttttttcttt ttgtcttgtt catgagtttc cgttatccct atagccatac
     1081 catcacgctt accgatactc catcaatacc actcaaaacc ttgtcatatc agatcttttt
     1141 gaccattttt ttcatgaata tctaaaaaaa agaatcaaaa tagtactaaa ttccccatag
     1201 cgcatgcgct atggggaatc atagctatat cttgtttata atttatgata taatacagca
     1261 aaaatagttt aggaaataac atatgacaaa aaaacactta ctaacacttc ttctcatctc
     1321 tttttttact agctttttgg tagcttgttc aacaacgaaa gataaagagc ctcaaccgtc
     1381 tgattcagaa atcattactc cccgactaca ccaagccgct catcaagata aacgcgctaa
     1441 ctttgaaaaa attaaacttg cgactgttga ttcctcattt acaggaggga caagccttga
     1501 agaacttatt tcactctttg gagagcctag ccaacatgat ccaaaaacag caggcgaagt
     1561 aacaatcgac gcttatactt ggcagtttga tcaagttact ctcactgtta atctttatca
     1621 aaatagtagt attgttaaaa ccatctctaa ttttaccttt gcaagagagt taggcttatc
     1681 gcaaaaggaa taccaacaat tacaaaaagg aatgtcttat gaagacgtta aaaagatctt
     1741 aacagaacct gataattata gccaagcgtc atctagtgat catcaaactt tgcaagcgat
     1801 ttgggttagt ggcttaaaga cagatacaag cggagctaat atttctctcg tttttgaaaa
     1861 taatcagtta acagaaatgt ctcaggtagg acttgaagaa taaaaaatgc gtaatatatt
     1921 ttgctaaaaa gattgatttc gatgtacacc gaaatcaatc tttttatatc attttaataa
     1981 aaaactttag tgtaatttct tataattgcc ttcatagatc gataaacaga cttgttttac
     2041 gcttaatgta ataattaatc taagtctgaa gaaaaatcat aagacagcat aaactactgt
     2101 cttatgattt agtttaagca tgttacggta ccgctacccc acattgcaat tattattttt
     2161 tatcgtgaat gccaaatatc ttcgttatac tgctcaatgg tacggtcaga tgagaagaat
     2221 ccagcttttg cgatgttatg gaccactttt gtcatccata aatcttggtc ttcatagtct
     2281 gctaacattt tttctttcac ttcaatgtac tcttcaaggt caatcaaagt catgaaccag
     2341 tcttttgaaa tcaattcttt ataaagacga tcaagacgtt cttcgttgcc aaatactagc
     2401 aattctggac tgataataaa gttcactgct gctttaatag caggatggtt atcatagtaa
     2461 tcttttgcta cataagaagc agtcgcataa aggttgatga tggtgtcaga atctttacca
     2521 aaggtataga tattctccat gcctgcaagc tcagcgattt ctacgttagc accgtccatt
     2581 gtaccaagtg ttaaagcacc gttaagcatg aatttcatat taccagttcc agaagcttct
     2641 ttggatgcta gtgaaatttg ctcagaaata tcagttgctg gaatcaagtg ctctgctact
     2701 gtcacgttgt aattttcaac tagatgcaca ttaaggtatg ggcttacttc agggtcattg
     2761 ttaatcaatt cagacaagca aaggatcaag tgaatgatgt cttgagcaat gatgtaagca
     2821 ggcgctgctt tacctccaaa gataacagtg attttacgtt ttggaaggtt gcctttttta
     2881 atttccaaat atttgtgaat cacgtaaaga gcattcatct gttgacgttt gtactcgtgg
     2941 aaacgtttga tttgggtatc aataatagaa tgttcatcaa gctcaatgta tttattgtct
     3001 ttaaggtaac gtttaagagc taatttgttg ttgaatttga tttcagccaa tttagcatga
     3061 acagctttgt catctgcaaa ggccatcaat ttttctagtt ttgttgcgtc agtcaagtac
     3121 tcatcgccaa taagttcttt aatgtaatca gccaagtctt ggttagcaaa ttctagccaa
     3181 cgacggaaag taatcccgtt ggttttgttg ttgaattttt ctgggtaaag gtcatagaaa
     3241 gcttttaatt cgctgttttt caagatttct gtgtggagtg ctgctacccc attgacactt
     3301 gttgcaaaat gaatatccat atgggccatg tgcacacgac ctgattcgtc aataatttga
     3361 acagctggat cagacacttc tgaacgaaca agagcatcca atttttcaat gatggttacc
     3421 aagtgtggca ctacttcgtt taagtaagca gttggccatt tttcaagggc ttctgcaaga
     3481 atagtgtggt tagtgtaacc aaccatattt ttcacaacag ctaccgcttc atcaaagtca
     3541 aagtcatgtt tttcagtcaa gagacgaatt aattctggga tgaccattga tggatgcgtg
     3601 tcattgattt gcacgtaagc gtagtctgca aggtcatgaa ggtttgaacc acgttcgata
     3661 gcttcatcaa tgattaattg cgctgcattt gacaccataa agtactgttg gtaaatacgg
     3721 agcaattccc catttttgtc agaatcgtct gggtagagga acaaggtcaa gtttttagca
     3781 atttgcgttt tatcaaatga aataccgtct ttgattaacc cgtaatcaac gccctcgata
     3841 tcaaacaagt taaggtagtt tttagtgtcg cgtttgtaac ccaaaacatc gatacgatca
     3901 agacgagatt tcaaggtgaa gttcttaaaa ggcacatcgt aagaaatgtc tgttggaacc
     3961 aaccatgagt catcttcaat ccagaagttt ggctcagctt cttgctcatt gtgtttgaag
     4021 acttgcttaa acaacccaca atgatagttt aaaccaaccc cttcaccatt aataccaaga
     4081 gatgaaatag agtcaataaa acatgaagca aggcgtccta aaccaccatt acctagtgat
     4141 ggttctaatt caacatcttc gacttctgcg atagacttac cagcagctgc caattcttct
     4201 ttgatgtctt tataaattcc taggttaatc aggttgtttg atagtaattt accaatcaaa
     4261 aattccgctg agatatagta aactttgcgt ttggcagtat ttttagcttt gtggctagct
     4321 tcttctttga caaagtttaa taatgataga taaatctctt cattgctagc ctgcgtaagt
     4381 gattttccta gtttagtttc aacatattct gtaaagcgtg tcatgtcttc ctcttttcaa
     4441 taatgtaaca tttaaatatt atcttgcgcg accataaaga tctgttaaat aaataaggta
     4501 atctttgtga tcttggttca attcaccgtc aagcatacgc cattgccaat tacctccaat
     4561 tgtatttggc atattcatac gactcttacc atctttatct aataaatctt ggatgcaaag
     4621 aatggctgta tcacaaacag aagcgaagat tgttcttagc atggcttttg taatactttc
     4681 atctgcatgt ttgtgaagat agttatttac aaagtgtact tgttcttcac taagattgtc
     4741 ataccatccg ttaaccacct cgttatcatg agtccctgtg taagcgacac aattacggtc
     4801 atagtaatgt ggtaaatcta tactttgact cgttatatca aataaaccaa attctaatat
     4861 cttcatgcca ggaaagcctg ttgatgctaa tagctgctct gctttttcat caatataacc
     4921 aaggttttct gcgatgatag gaagctctcc taaggcctca cgaaccgcag aaaataacgc
     4981 tatacctggg gctgaggccc aatggccatt tctagcagtt ttatcaccag caggaatttc
     5041 ccaaaaatct gagaagcctt taaaatgatc gattcttagc tgatcatata gtttgaaact
     5101 ttcttgaata cgataaatcc accatgcaaa attagacttt tcatgagcag accaattgta
     5161 ggttggattt ccccacagct gaccatcttc actaaagcca tctgctggta cacctgcaat
     5221 aaacaatggc tttttatcac tatctacttt aaatagctca ggcatcgtcc aaacttctac
     5281 actgtccgca gaaacataaa taggcatatc accaataatt tctatccctt tatggttagc
     5341 gtaagttttc aaggctgacc attgttggta aaagaagtat tgacagactt tatgataggt
     5401 aatctttttt gcaagcaact cacggtaatt attaagtgag tcttcttggc gtttaatgac
     5461 agtttcgtcg tcccaatctt gtaaggcttt attgttaaaa tattctttta aagccataaa
     5521 ttcagcaaaa tcagttaacc agctagaagc tgtttcaaaa gcttctaatt tacacacatt
     5581 ttcttgttca gcaacaaaag ctctcactgc tttttctaaa agtggacgcc taacttgaaa
     5641 aagctgagca tagtctactg cttcaggatt tgtgccgaat gtaatatcac acaaatctgc
     5701 tgcttctaaa agttcatcat ctactagcaa ttcaaaatca atgaaatgtg tgttcccagc
     5761 aatagctgaa aatgactgat aaggagaatc tccaaaactc gtcgttgtta aaggcagaat
     5821 ttgccaatag gtttgtttcg tctctgctag aaaatcaaca aattcaaaag ctgattttcc
     5881 aaaagtgcct atcccaaatt tcccaggcag ggaactaata tgcattaaga taccgcttgc
     5941 acgtttgttc atgatttttc tccttgtgaa atctattcat gatgagatta taacgcaagc
     6001 gcttgcgtaa gtcaaccagt ttcctaaaag aaagtaacat tccttaaaaa tgctactttt
     6061 ttgttcttaa tgactaatat cacggacgct ttctctttgt tttaaactaa aaggaacaaa
     6121 aatagtctga ctaagattct gttcattgga attgataata tcaagtaatt gcttaaaaga
     6181 catttttcca agattttcaa catttatatc aaatgtcgtt aaataagggt gaattaattt
     6241 agcgtaatta gaattattaa aagtgataat tgacatatca tctggcactt ttatatcata
     6301 aaaagataat aactgtacca tacgaatagc cagaacatca ccaacaacaa ccaaggcagt
     6361 tgctttaaag gaagatatag tttccatcaa tatttctacg ctaacaggat ccttacgatc
     6421 aaataacagc attggcttcg tttttaaaga tcgcttaaaa caacccttca aatagccaag
     6481 ataacgctca gaagttactt ctgatagtaa atcatctgtt ataaataata tgttgtgatg
     6541 gcctttttga taaaggtgtt ctactgctgt tttagccatt aactgattat cattatcaat
     6601 ataagtggtt ttattagtgt caccttgtgg agcacctaca atgacaaatg gtaagttatt
     6661 tgtcatcaaa tattttttga caggatcatc ttgatcagaa taaagaataa taaaaccatc
     6721 aactcgtttt tgaagatgca tcagtttcac ttgctctatc aggtcatcaa gagatatacc
     6781 tgtagcaatc gatacagtaa aatgagattc tttagcttcg ttagtaatag tcgacaaaat
     6841 ttccataaag aaaggctcac ttaatctatc gctagttgta ataggaggaa aaacaagtcc
     6901 tatattgtgt gtcaaaccac tcgctagaat ctgtgctgcg acatttggaa catatcccaa
     6961 atctgccatc gcttttctaa ccttctcttt tgttttcata gaaatagatc gattatcttt
     7021 taatacccta ctcaccgtcg aagggttaac acctgccttt tgagcgacat cttttattgt
     7081 taccatatta acctcgttac tatatttacc aaagataaac cttatcatgg gtttgtcatg
     7141 tatttcgttt ccattataca attatctttc aaaaaatcaa cttcaatcaa gattcccttg
     7201 tcattttaac tcaaattctc taaactattt tttaaaaaaa acgacctttt tttaaaaaaa
     7261 aggcttgact ttttctgcaa gcggttgcat aatattaagt gtaagaaata tatcttagga
     7321 ggaaatagct atgaaatcat ggcaaaaagt tatcgtcggc ggagcaagtt tgacacttgc
     7381 aagtaccttg ttagtgggat gtggatcagg ttcaaaagat aaaaaggaag ctggcgctga
     7441 ctcaaagact attaaacttt gggtaccgac tggctctaaa aaatcatatg cagataccat
     7501 tgcaaaattt gaaaaagatt ctggttacac cgttaaagtg gttgaatcag aagatccaaa
     7561 agcacaagaa aaaatcaaaa aagatgcctc aactgctgcc gatgtctttt cacttcctca
     7621 tgatcaactt ggtcaacttg tagaatctgg tactattcaa gaagttccag aaaagtacaa
     7681 taaagaaatt gctgctactt ctactgatca ggcgctcatc ggtgcacagt acaaagggaa
     7741 aacgtatgct ttcccatttg gtattgaatc acaagttctt ttctacaata aatcaaaatt
     7801 agctgctgaa gacgttactt catatgatac aattactaca aaagcaactt ttggtggtac
     7861 ctttaaacaa gctaacactt acgctactgg tccattattc atgtcagttg gtaacacttt
     7921 atttggggaa aacggtgaag atgtaaaagg tactaactgg ggcaatgaaa aaggcgctgc
     7981 tgttcttaaa tggatcgcag accaagcttc aaataaaggt tttgttagct tagatgctaa
     8041 caacgttatg tctaaatttg gtgacggttc agtagcttcc tttgaatcag gaccgtggga
     8101 ctatgaagct gctcaaaaag ctatcggtaa agaaaacctt ggtgttgcta tttatccaaa
     8161 agtaactatt ggaggcgaaa cggttcaaca aaaagcattc ttgggtgtaa aactttacgc
     8221 agtcaaccaa gcaccagcta aaggtgatac aaaacgtatc gcagctagct acaaattggc
     8281 atcctacttg actaatgctg aaagccaaga aaaccaattc aagactcgta acattgtccc
     8341 agccaacaaa gaagttcaat cttcagaagc tgttcaatca aacgaacttg ctaaaaccgt
     8401 tatcactatg ggttcttctt cagactacac tgtcgtaatg ccaaaactta accaaatggg
     8461 cacattctgg actgaaagtg ctgctattct tagtgatgcc ttcaacggta aaatcaaaga
     8521 aagcgactac cttactaagt tgcaacaatt cgacaaagat attgctgcaa caaaataata
     8581 tgatctcatg tcatcactgc tatactaaaa caagcacaag gtaagtactt ctaaaaagtt
     8641 ctttccactt accttatgaa gagtggaact aggctccatc acattttatt caagcttagt
     8701 ctcactctta cttgtttttg ttttactagt agcttagtgc tacttaaatt tttaactctt
     8761 taaaagttta cgtaacactt agctatttca tcctaacaag agattgaatc tgaactacca
     8821 ctctagtatc ctaaaataaa ggagaatcta tatgactcag tcaaacttga caccaaatat
     8881 atctgtaata gaagccttaa aaagaggcag ttgggatatt aaactttcga gtattatcat
     8941 gggatttgcc aactttgcta acaaacagtt tatcaaagga atcttatttt taataagtga
     9001 acttatcttt ctagtagctt ttgtctccca aatcatccct gctatccttg accttgtcac
     9061 tcttggtact caaactcagg gaatgactac aaaaactatt gatgggatta acatccaagt
     9121 tgctgttgat ggcgataact ctatgctaat gcttattttt ggtttagcat cactcatttt
     9181 ctgcctagtc tttgcttaca tttactggtg taatctcaaa agtgctcgta acctttatct
     9241 tttcaaacaa aaaggtcaga agataccaag cttcaaagaa gatcttgcca cacttacaaa
     9301 tggtcgcttt catatgactt taatggctat cccactgatt ggtgtgcttt tattcaccat
     9361 tcttcctttg atttacatga tctgtttggc ctttaccaat tttgatcata atcacttgcc
     9421 tccaaaatct ttatttgatt gggtgggact tgctaacttt ggaaatgttt taagcggccg
     9481 tatggcagga accttttttc ctatcttctc atggactttg atttgggctg tttttgccac
     9541 agtaactaat ttcttctttg gtattattct tgctttgtta atcaatacca aaggattaaa
     9601 gtggaaaaaa atgtggcgaa ccatctttgt tatcaccatt gcagttccac aattcatctc
     9661 attattgatt atgcggaact tactcaatga cgaaggccca ctaaatgctc ttctcaataa
     9721 aatcggcttg attaatggct cactgccatt tttatctgat cctctttggg caaaattctc
     9781 aatcattttt gtcaacatgt ggatcggtat tccatttacc atgttgattg cgactggtat
     9841 tatcatgaac cttccaagtg aacaaattga ggctgctgaa attgatggcg ctagcaaatt
     9901 ccaagtcttc aagtctatca cgttccctca aattctcttg atcatgacac caaacttgat
     9961 tcaacaattt atcggaaata tcaataactt taacgtcatt tacctcctta ctggtggtgg
    10021 tccaacaaat tcagaatact atcaggcagg aacaacagac ttgctggtca cttggctcta
    10081 taaattaacc gtcacagctg ctgactacaa tttagcttct gttatcggta tcttaatctt
    10141 tacagtttca gctatcttta gcttacttgc ttatacaagg acagcatctt acaaggaagg
    10201 agcggctaaa taatgaaaaa caaacgtcga tttcaacttg gacttgttta tgctacttta
    10261 atcatcctct caatcatttg gctcttccca atcgcttggg ttattcttac tagcttccgt
    10321 agcgaaggaa ctgcttacgt caattatttt attcctaaga cttttacatt aaatcactac
    10381 attaatcttt ttactaatga aacctttcct tttggaaaat ggtttatgaa tactcttatt
    10441 gtagccactt ttacatgtat tatttcaacc ttcataactg ttgccatagc ctactctctt
    10501 agccgaatta agtttaagtt tcgcaatggc tttttaaaac tagcccttat tttaaatatg
    10561 ttccctggtt tcatgagcat gattgccatc tactatatct taaaggcctt aggtttgacg
    10621 caaaccctaa cagcacttgt ccttgtttat tcctcaggtg cagcccttgg tttttacatt
    10681 gcaaaaggat tttttgatac cattccttat tcacttgatg aatcagctat gattgatggc
    10741 gctactcgta tggatatttt ctttaaaata acccttcctt tagcaaaacc aatcattgtc
    10801 tatactgccc ttcttgcttt tatggggcct tggattgact ttatctttgc acaagttatt
    10861 ttaggtgatg ctacaagtaa atataccgtt gctattggac tattttcaat gcttcagcca
    10921 gataccatta acaactggtt tatggccttc actgctggtt ctgtcttaat tgccgtccca
    10981 atcactctcc tcttcatgtt tatgcaaaaa tactatgttg aaggcatcac aggtggttct
    11041 gttaaataag ttacaacata ccaaaccttc taagggcaag ccctttagga ggtttttgat
    11101 aaataagacc gtagataatc atattagtcc tcacatttat cttcagatcc cgcgttgtaa
    11161 aatgaagtgc aacaaaaaag acatgttcgt ctgatatact agaattcccc aattcagtat
    11221 ggaaagcaga tgaacatgtc taatattaat tctaccagaa aatcctccta ttctcatctt
    11281 tcagccacag aacggggtga aattgctgct tatcttaaaa tgggaaagaa acccgttgag
    11341 attgctcgac tcctgggttg tcaccgttct acaatctgcc gagaaataaa acgtggttca
    11401 gtagaacagg taaaggataa gaatgaaaaa caaaccttct tcaacgccta tttcgctgat
    11461 agtggacaac gtgtctacga aactaatcgt caaaagagtt cttacctcaa gttgaatgat
    11521 tgcttcgcta ggttcattgc acaattagaa tctgccttga cggctaacat tcgtctccat
    11581 agtgtggata gttttgttca gacttacaac gtgaaccacc ctgaagaagt cgtcccctct
    11641 accaaaacga tttatcatta tatcaaagag ggggtgttag ctattaaact aatcgatttg
    11701 cctaagatgg ttagtatcag aaaacgttct aagaaagtca tgaagacgaa taagaagact
    11761 ttaggtaaat ctatcgaaga acgtccagaa tatattaatg atcattctga atttgggcat
    11821 tgggagattg atttgattct cggcaagaaa accaaaggtg aagctgttat gttgactttg
    11881 gtagagcgcc agacacgcta tgcactagga gttaagctag aagacaagcc gtcccaaacc
    11941 attaaccgtg ctgtcacgca tctcatcagt cagtatccta ttgcatccat cacagcggat
    12001 aatggttctg agtttagttt actctcacaa tgagcgccca agacgacttc ttcaatagca
    12061 atcctcaaaa ttcctgtttg agctatcccg aacagcttaa cctctggaac tctagttatc
    12121 tatgaactcg ttgcacttga cttgacaact tgcgagagca tatcagtagt ttttctgcta
    12181 attgaaaaca gggtatttac tgtcacacaa gtctgtcctt tctttttttc tacaacttta
    12241 tttcgtcagc gtaaataaaa caaaagctct ataatctctt gaatgggtaa atccactgta
    12301 gagattatag agctttttga atatcaaaaa agtcccataa gatttataat gaaaagcaac
    12361 caaactctca ttagaaagac tcttatggaa catatcaatc ataccttaca acacatcgga
    12421 attaaagaca aaaatatcac tctaaacaat gttttgaagg atgaatctcc tactgagctc
    12481 gttactactt atcagaaagg tagataggaa atcctgatga agagtgtgtc caagggatta
    12541 tcaattaggt cttagattac aaaatagtaa ttcaggtatg ctctactgtt ttcaacacta
    12601 gttctgcaat ttgttttcga gcttgcttag cttctcttat ttgaaaaata acatacgcat
    12661 gaatcatttt ttctgcaata atcagctgat tagcaattcg ttgtcttgtt aattgatcat
    12721 gtaaagacat aatgtctggg taaaaaattt cttttgtccc aacaaaggtc gttatttcag
    12781 gcaaatcctc ataatcacca tacaaaggac tgacataagg aagttgcata ttaccttgac
    12841 cacctgccca tagttcacct atatcacgaa gacgacgagc atctaggtaa gcttcttctg
    12901 cttcaaaatc cttgtaggct tgatttttaa aactaacatc taaccaagga gatataagaa
    12961 ttaattgctt tggctgtagt gctgttttag tatctcgtat atacttagca aacgccaaag
    13021 ccatcccccc accagaagaa tcaccaatga cactaacttg actcggtcca ttagacaagc
    13081 aaaattgctg gtaagcttca actaatttag gatagacatc ttgataagta gcatacggta
    13141 ctttaggaaa gttaggaaaa acaaccttgg cattagtcag ctgtataaga tgcttaaccg
    13201 tcttaaaatg aagtttttcg ggtcgtcgta aatagacact gccataaaga taataaataa
    13261 caggctgatg actttgcttt tgatcattaa taataaaaac ttgcatcccg ttcacatcgt
    13321 attcttgagt tgaaaaacct actatctctt caggattatc tagatgataa gggatattac
    13381 gattacgctg cgtctcaacc cccttataat tatcaacttt tttagataac ttatactttc
    13441 tataagcaaa cattttctca accaaccaac ttgaaaagga gcgcttttga ccatattcaa
    13501 ctatcaaaat acctagtatc actccaaaaa aaatcaccac agcaataatg accacttatt
    13561 atcctcgttt tctaatatta ttttactatt gcaagtcttt cctatttgcc caaattttac
    13621 tataaaaata agggttcatt ttatagttgg gtactggttg cttcgtttct agaaatggtt
    13681 gcactttctt atcaaaagct aaccagccat tccaaccgag atggatggta tcttgcataa
    13741 agtaggactc accaccatct tttgagaagt cagcaatgcg atgaaatcct tgtgacttta
    13801 actggaattt tattttacga actgccgctt gatacttatc ttgatttaag ccggtataat
    13861 ccgcccaagc tttattaaca ggagttataa caaagagtac atctgttttt cgtttagcaa
    13921 attctgataa caaaagctga aaatcattgt attctggtga cgccaggtaa ctataattaa
    13981 cttggaaatt cttataaaaa ttgtatttag gtgctattcg tttacgataa aatgtatttt
    14041 taatcccaaa acggttgttg gttgttgcta attggcctct cttagttgct aacgcattca
    14101 attgtttata cgaaaatact ttaggtaatc ccttaacgcg aggcaaaatt cttttttcat
    14161 agttagtaga tttgcctaaa aaactaaaaa gggactcttc tctcaatgct acttgatgtt
    14221 gacatttcaa aatagctctg tctaaccgac taagagactt acccttactt acttttttca
    14281 ataagtttga tttagacaca ccagggttaa gctcaagcaa acgctttgct gcaaactgtg
    14341 attctttatc agttctagct tttagtaaaa attcaatcac ttgagtgtta gacaagtaca
    14401 tctgaaccgc actaggatta atcccttgag cagtaaacca ttgaggagat actacaaaga
    14461 tggctttttt cttttgcatt tcattggtaa tttgttgcat accataataa tgcgacaaag
    14521 atgctgatcc tctcttacca attaaaaatg gtctatagct ccgcttgtag cgctctgcaa
    14581 gcaccgaagg gtgcatacta tccattcgac tccattcgct agaaccaaaa aaaggcacaa
    14641 aacgacaagt ctcatctgat aaagcttgtc ttttaatcaa accattttta aaagaactat
    14701 ctgtgatcgc aacggcattt gctttttcct gagctatgga atgatcaagt tgtgtaggaa
    14761 aactaaaaat agtaatcact actaaaacaa aggcaataag aagaggacct agaattaacc
    14821 agagtctctt aagcatgttg caattcctct acaccttgaa caatcttagt tactgtgttc
    14881 caatcatcac gaccaaattc tgaaataggt actttaatat tgaacgttga ctctaactca
    14941 acaatcaatt cgactgtccc aagactatcc aacacacctg catcaaacaa gtcttcgtcc
    15001 atcatctctg aaacatcttc cataaacaaa cggtcaaaca attcaattac agtttcttca
    15061 atagacattt ttatacttcc ttttattaat gtagtggtct gttaaaccaa aggtcattta
    15121 aaaaaccaga gaataacaga agtgaaaaca tgacaacgtg gaaagttacc acgatacata
    15181 agacatggaa tgccctgctt tgaaagaggg gtgataagcc ttttttctta cggtgacggt
    15241 tgatttcttt tttcttacga atccaagcat cattaataat aagtcctata ccatggaaaa
    15301 gcccataagc gatataatac caggttaagc catgccaaaa tcccatgact agcatattaa
    15361 ccagataggc aacacctgaa gtgacatttc ggtttttaaa ggttttatgc ttaatcaata
    15421 gatgaaccaa tcgcataaac acataatctc taaaccagaa ggacaaactc atgtgccatc
    15481 tattccaaaa atctttcaaa cttgcagata agaaaggcat gttaaagttt tctggtgttc
    15541 gaatacccaa taggtaggaa ataccaatcg caaacatcga ataaccagca aagtcaaaaa
    15601 agagattcaa gccatacacg tacataacca gaatagtttc cttattaaag tagccaccaa
    15661 ccatcaaagc cttattttca aggagaggaa gtaagatgcc acccaaacaa taggaaatga
    15721 tatgcttgta taggaaacct aacatgagat acatgactgc cttattgagc attgcaaaat
    15781 aatcatcacg ttcaggaagt ttatgataat cttcctgaaa acgtctgaag cgatcaatgg
    15841 ggccacttga gaaagtgggg aagaaaatca tgaagcgaat aaaatccggt aaacgaacct
    15901 cttggagagt cccgtcacgc atctcaataa tcattccaat acttttaaag gtcaaatatg
    15961 aaatccctag aaaactaaag agtgttcgag aagaaggacc tgttagggga gcaactttga
    16021 cccagataag ggggaataag gccatcgcaa tagctaagta aaacactcct gcactattag
    16081 ctttctcacg atatttctgg taagcaaaaa cactgatgat ttgccacaaa agataaaaga
    16141 gaaaagcaac taattgttga taatgatctc ctccaaacat aaagagaata aataccaaac
    16201 tcaccaaggt ttcataagtg cttaagcgct tttgtttaaa aatcccaatg atgactggta
    16261 agaaagccaa aataagatag acaaagtaaa tggggttacc gtaaggttcc atgtagggaa
    16321 tgtggctaaa aaacatcatc atcggttatt gacctcatta atcaaagttt taatatctat
    16381 cttaccattt ggagttaatg gtagactatc tcgataaaga aacttagaag gcatcatata
    16441 actcatcata tgatccttaa cagaggcttt gatagctttg gttaactcca attccctatc
    16501 aaaacgctct ttaaccccat ctttgacaac gatataggcc aagagatttt gaaccttatg
    16561 ttctttattg taccttggaa cagccacagc cgatgctacc attggtgatt gattcaactg
    16621 ttgggaaaca tcttctagtt caatacgata accagcatat ttaatctgaa aatccaaacg
    16681 cccaccatac agcaaaatat tatcttctgt caatgagcca atgtcccctg tatgataagc
    16741 aggctgtcct ttaaaagtaa agaaagcttc tgcggttttc tcaggattgt tgaggtaacc
    16801 ttttgacaca gcaggccctg taacaataat ttcaccctgc tcccctgaag ataactcctt
    16861 accatcttca tcaataatat aggtcggaga atctggtttg gggtagccaa tcggcaagcg
    16921 ggtataatta tccaccattt ctctagtaat ttcaatagcg gataaggcta cagtcgcttc
    16981 tgttggtcca taggcattga taatcttggc actcgggaaa cgttcaaaga gttttcgagc
    17041 cgtagaaacg gttaattctt cgccatcaaa ataaaaatgc gttaaagctg gcatcttagc
    17101 ctggcaaaaa tcatcgctaa gcatggccat atcagcaaat gaaggagtcg atgtccaaat
    17161 gccaactgga agttgcgcaa tcgttgtaaa taactgttta aagtctgcca ccaattcttt
    17221 tggaagtgca aataaggttc cacctaaagc caaggtaggt gcccagtaca tgacagaaag
    17281 gtcaaaggaa tagggtggct gcgccagcat ttgtggctgt ttaggtacat caaatgctgc
    17341 atcttcgatc atccagttgg taaagctcaa aagattgtca tgtgaaattt gcaccccttt
    17401 tggttggccc gttgttccag aggtgaaaat aatgtaataa ttatcatctc ctttaacaga
    17461 atgtgttcgc tcatagggca tttctgctaa ttttgctgac tcaatctctg atagtgagac
    17521 aagggaaatc ccttcaatag taagagggaa ttcctcaata gcaatgatta aactgggctt
    17581 tgcaatctca ataatcgcta aaatacgttc tggtgctgaa tgcacatcta ctgggatata
    17641 ggcatgacca gatttggtta aagctacaaa agtagctaac atatcataag tttgcgcccc
    17701 aaaaaccaaa actggagatt ttgccagtaa agctaagcta tctataaatg cagcaatgct
    17761 atcagaatct cttttgagtt gtccgtaagt gcggcgttcc cctaaacaat cataaactgg
    17821 aaaatcagcc tgtgtctgag caaactgctc aatactgtca atcatatcct taatcatcag
    17881 tcaatctcct aaaattcatt ataaataaag ttactttgac catgtcctag ataaccaaag
    17941 aaatagacca gcaacattaa aatcagataa aataaaattg tcttgccaat aaaaacagca
    18001 attcctctca ttcttgattt gttttttatc atactttacc ttcttgtatt agtgaaataa
    18061 tgtcctaaaa aattctactc gaaaaaacct aacttgacaa gctaaaagtc atattattaa
    18121 aaagaaaatt tttttaaagc ttaactattt agacagttaa attttatgcc tttttactaa
    18181 acttactaag ttaatcttta ctttaaaaag ttaacttaaa attgtccta
//
LOCUS       DAUGSW010000029        16926 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUGSW010000029 DAUGSW010000000
VERSION     DAUGSW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16926
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.029"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(21..2012)
                     /gene="uvrB"
                     /locus_tag="VIB18_001231"
     CDS             complement(21..2012)
                     /gene="uvrB"
                     /locus_tag="VIB18_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEQ8766237.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     TEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            2205..4379
                     /locus_tag="VIB18_001232"
     CDS             2205..4379
                     /locus_tag="VIB18_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8766238.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQANALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTIKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFKTPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            4379..5119
                     /locus_tag="VIB18_001233"
     CDS             4379..5119
                     /locus_tag="VIB18_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766239.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEAAKKHGMALLEKVGLSDKADTFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(5267..5419)
                     /locus_tag="VIB18_001234"
     CDS             complement(5267..5419)
                     /locus_tag="VIB18_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766240.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(5416..6795)
                     /locus_tag="VIB18_001235"
     CDS             complement(5416..6795)
                     /locus_tag="VIB18_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8766241.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVITAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(6973..7422)
                     /locus_tag="VIB18_001236"
     CDS             complement(6973..7422)
                     /locus_tag="VIB18_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEQ8766242.1"
                     /translation="MIISAEGDVSIHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYQLEALGENRTRITYSYD
                     YHPLDIFQKANQFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(7419..7754)
                     /locus_tag="VIB18_001237"
     CDS             complement(7419..7754)
                     /locus_tag="VIB18_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8766243.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(7757..8068)
                     /locus_tag="VIB18_001238"
     CDS             complement(7757..8068)
                     /locus_tag="VIB18_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8766244.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(8091..10085)
                     /locus_tag="VIB18_001239"
     CDS             complement(8091..10085)
                     /locus_tag="VIB18_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8766245.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEIIHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVI
                     NNLVLHIALMVQRIRSGCPLELFSIPTAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPTQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(10191..11285)
                     /locus_tag="VIB18_001240"
     CDS             complement(10191..11285)
                     /locus_tag="VIB18_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEQ8766246.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEEHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDNLRPWQEFCLEIAPS"
     gene            complement(11294..12694)
                     /locus_tag="VIB18_001241"
     CDS             complement(11294..12694)
                     /locus_tag="VIB18_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8766247.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSNAPEDVKAARIAELFQTKSFLDPSVLGIYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVKGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            12919..13614
                     /locus_tag="VIB18_001242"
     CDS             12919..13614
                     /locus_tag="VIB18_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEQ8766248.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDSSQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            complement(13619..13777)
                     /locus_tag="VIB18_001243"
     CDS             complement(13619..13777)
                     /locus_tag="VIB18_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766249.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(13846..15159)
                     /gene="obgE"
                     /locus_tag="VIB18_001244"
     CDS             complement(13846..15159)
                     /gene="obgE"
                     /locus_tag="VIB18_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEQ8766250.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAEAEKEFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD"
     gene            complement(15216..15344)
                     /locus_tag="VIB18_001245"
     CDS             complement(15216..15344)
                     /locus_tag="VIB18_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEQ8766251.1"
                     /translation="MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM"
     gene            15586..>16926
                     /locus_tag="VIB18_001246"
     CDS             join(15586..16036,16036..>16926)
                     /locus_tag="VIB18_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8766252.1"
                     /translation="MKFNQETKVKIYELWQMGESIKSISKKFDMAESDLKYMIRLIDR
                     YGVTIVQKCKNHYYSLELKQEIINKVLIDGQSQKQTSLDYALPTSSMLSRWIAQYKKN
                     GYTILEKPRGRPSKMGRKRKKNLEEMTEVERLQKELEYPRAENAVLKKPERIPLEGRS
                     KAQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDE
                     HKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADN
                     LIKRHFEGSKPYEKCYTDVTELALPEGKLYLSPVLDGYNSEIIDFTLSRSPNLKQVQT
                     MLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILPSMSRKGNSPDNGMMDSFF
                     GILKSEMFYGLKTTYQSLDKLEEAITDYIFYYNNKRIKAKLKGFSPVQYRTKSFQ"
BASE COUNT         5158 a         3574 c         3067 g         5127 t
ORIGIN      
        1 atataagctt tattcaaaac ctagtccatt aatttaagtt ctaaaatcaa gtctcgcatt
       61 tgagctgcca attcgaaatc aagtaattca gctgcctctt gcatttgttt ttgcagagca
      121 ttgatcgctt cttttcgttc tcctcttgac atactttcat aatccatctc ttctttcgat
      181 atatcattgt ggcttgtttt acttatacta ataaggcctc tgatgtcttt ttttatagtt
      241 tgtggaacga tgccgtgcgc tttgttatat gctatttgaa tctcacgacg acgagccgtt
      301 tcgtcaatag cccgctgcat agaatctgtc atcttgtccg catacataat gacatgacca
      361 tctacgtttc gagctgctct accgatggtc tgaatcaagc cgcgttcatt acggaggaaa
      421 ccctctttat cagcatccaa aatggctaca agactaactt ctggcacatc aatcccttca
      481 cggagcagat tgattccaat caagacatca aaaacaccaa gtcgtaaatc acgaataatt
      541 tctgtccgct ctaaggtttt aatatcactg tgcatatact tgaccttgac acccatctct
      601 tttagataat cagtcaaatc ttctgccatt tttttagtta aggttgtgat gaacgtccgt
      661 tcatcgcgcg ctacgcgctg gttaatttct cccaacaaat catccatttg ccccatactt
      721 ggccttacat caatttcagg atcaagtagc ccagtcggac gaataatttg ctcaataatt
      781 gtattagtct gtgacatttc gtattcacca ggcgttgctg aaacatagac aatttggtgc
      841 acatgacttt caaattcctc gcgtcttaag ggacgattat caagagctga tggcaatcga
      901 aaaccatagt caactagcat ttgttttctg gcttggtcac cattatacat gcctttgatt
      961 tgtcccattg tcatgtgact ttcatcaatc ataattaaaa aatcttctgt gaagaaatct
     1021 aacaaggtat aaggaggttc tcctggtgac ctgccatcca tatgacggga atagttttcg
     1081 actccgctag tatagcccat ttcacgtaac atttcaatat catattccgt tctttggcgt
     1141 aatcgctgtg cttctagtag tttaccttca gattcaaata actgtaactg ctctgctaac
     1201 tctgcttgaa ttttggctat tgattgctcc atatgctcat catttgttac aaagtgagta
     1261 gctggaaata aaaccaaatg gtcaacttct ccaatagttt tcccagttaa actttcgatt
     1321 tcacatatac ggtcaatctc atccccgaaa aattccaccc gaaaagcatg ttcatccctg
     1381 gatgctggaa agacctcaac aacatcgcca cgtacacgaa aacagccgcg ttgaaaatca
     1441 atatcattac gctcaaattg aatatctact aattgattta gcaaagtgtc acgtgatatc
     1501 tcctgacctg gacgtaggct gactgctgaa tctgcgtact cttttggcga acctagtcca
     1561 taaatacaag atacagaagc taccactatg acatcgttac gctcaagtaa agaagaggtg
     1621 gctgaatggc gaagtttatc gatttcatca ttgactgaac tatctttttc gatataggtg
     1681 tcgcttgatg ggacatatgc ttcaggttgg tagtaatcat aataagaaac aaaatattcc
     1741 acagcattgt ctggaaaaaa ttctttaaat tcaccatata attgtcctgc taaggtttta
     1801 ttgtgagcta tcactaaggt aggtttattt actttactaa ttacttggct catggtgtat
     1861 gtttttcccg ttcctgtagc acctaggaga atctgagctt tttctccgcc ctcgatatta
     1921 tcaactaggc tttcaatagc ttgtggctga tcaccagacg gtttatactt tgattttagt
     1981 ttaaatggtt tatcatcacg tttatcaatc attttatacc ctctaatagt cttactctct
     2041 tatagactat tttaacatag ataagccaga atcacctcca ataagcgtaa aaaacatgtc
     2101 atttacatgt tatgttttat gacatataaa taacaaattt cttgcttaat gttcaatatt
     2161 ttgttataat taaccatatt ttttagtttt ataaggagat tagtatgacg cacaaaataa
     2221 aagtattgct gcttgcgata atgtctattt ttttgacatg caatattgca agtgctgaaa
     2281 ctattgctat tgtttcagat acagcttatg ccccatttga atttaaagac tcagatcaaa
     2341 tttacaaagg aattgacgtt gatattatta atgaagtagc caaacgtcaa tcttgggatt
     2401 tcagtatgag tttcccgggt tttgatgcag ctgtaaatgc tgttcaatct ggtcaagcga
     2461 atgctctaat ggccggtaca accattacga atgctcgtaa gaaagtcttt catttctcag
     2521 agccatatta cgataccaaa attgtcattg cgacacgtaa agccaatgcc atcaaaaaat
     2581 acagtgactt aaaaggaaaa acggtcggtg ttaaaaatgg aacagcggct caagcctttt
     2641 tgaataacta taaaaaaaag tatgattata ctattaaaac atttgacaca ggtgatctta
     2701 tgtataatag tttatctgct ggttctattg ccgctgttat ggatgatgag gcggttatcc
     2761 aatacgcaat cagccaaaac caagatattg ctattaacat gaaaggagag cccattggaa
     2821 gctttgggtt tgctgtcaaa aagggaagcg gatatgatta tctagttaat gatttcaata
     2881 cagctcttaa agctatgaaa gctgatggta cctaccaagc tatcatgacc aagtggttag
     2941 gcacagatga taaagctacc accagtcagg caacgggaaa tccatctgcc aaagctacac
     3001 ctataaagga cagttataaa attgtctctg attcgtcttt tgcacctttt gaatttcaaa
     3061 acggtaaggg caaatacgtt ggtattgaca tagaattaat caaagctatt gctaaacaac
     3121 aaggtttcaa aattgaaatc gctaatccag gtttcgatgc tgccttaaat gctgtgcaat
     3181 ctagccaagc agatggggtc attgctggtg caactattac tgacgctcgt aaagctatct
     3241 ttgatttttc tgatccttat tatacttcta atatcatttt agctgttaaa gctggaaaaa
     3301 acatcaagaa ctatgaagac ttagacagaa aaacagtcgg tgctaaaaac ggcacttcat
     3361 cttactcttg gttaaaagaa aacgctccta aatatggtta taatgtcaag gcatttgatg
     3421 atggttctag catgtatgat agcttaaatt caggttctgt agatgctatc atggatgatg
     3481 aggcggttct taaatacgct atctctcaag gtcgtcgctt taaaacacct cttgagggca
     3541 tttctactgg tgaagttggt tttgctgtca agaaaggaac taatccagaa ttaatcgaaa
     3601 tgttcaacaa tggcttagct gctctcaaaa aatctggtca gtatgatgac attatagata
     3661 aataccttga ctctaagaaa gctgcaactc cttctgaaaa aggtgctgat gagtctacta
     3721 tttcaggcct attatcaaat aactacaaac aactattggc aggacttgga accacgctca
     3781 gtttaaccct tatttcattt gctattgcta taattatcgg gatcatcttt gggatgatgg
     3841 ccgtgtcacc aactaaatca cttcgactca tttcaacggt ctttgtggac gttgttcgag
     3901 ggattccttt gatgattgtg gctgccttca ttttctgggg agtaccaaac cttatcgaga
     3961 gtatgaccgg ccaccagtca ccgattaatg atttcttagc tgctacaatt gcactgtcac
     4021 ttaatggcgg agcctatatt gctgaaattg ttcgcggtgg tatcgaagct gttccagcag
     4081 ggcaaatgga agctagtcga agtcttgggt tgtcttacgg aaccacgatg agaaaagtaa
     4141 ttctcccaca agctgtgaaa ctaatgttac ctaactttat caatcagttt gttatttcat
     4201 tgaaggatac aacaatcgtc tcagcaattg gtttagtgga actcttccaa acaggtaaaa
     4261 tcattattgc tagaaattac cagtcgttcc gtatgtatgc tattttagca attatttacc
     4321 ttatcatgat tacactctta acaagacttg caaaacgttt agaaaagagg cttaactaat
     4381 gacagaatta aaaattgatg ttcaagattt acacaaatct tatggtcaaa atgaagtctt
     4441 aaaaggaatt gatgccaaat tctacgaagg cgatgtcgtt tgtatcattg gtccttctgg
     4501 ttctgggaaa tcaacctttc tacgtaccct caacctccta gagacgatta ccagtggtaa
     4561 ggtcatggtg gacggttttg aattatcaga tcctaagact aatattgaca aggcacgtga
     4621 aaatatcggg atggtattcc aacacttcaa ccttttccct cacatgactg ttcttgagaa
     4681 tattatcttt gctcctgttg aattaggtaa agagtctaaa gaagctgcta aaaagcacgg
     4741 catggcactt ctagaaaaag tcggactttc tgataaggcc gacaccttcc caggaagttt
     4801 atccggcggg caaaaacagc gtgtcgccat cgccagaagt ttagcaatga acccagatat
     4861 catgcttttt gacgaaccta cttctgccct tgacccagaa atggttgggg acgttttgaa
     4921 cgttatgaaa gacttggcag aacaaggcat gaccatgtta attgttactc acgaaatggg
     4981 atttgctcgc caagtagcta accgcgttat ctttacagac ggtggtcaat tcttggaaga
     5041 tggtactcct gaagagattt ttgatcatcc taagcaccct cgtctcattg aatttttaga
     5101 caaggtctta aacgtctaat agagcagaca ccatactaac ttccaaaaaa taaaaaggca
     5161 aggaaacagg tttccttgcc ttttttggtt actgttatta ttcaaaccag caaaataggg
     5221 atactcttat gactctctcc ttcataagag tgtcccctat gcttttttat gggcgtttat
     5281 gtttagtgag gtaataacct aatcccgtaa gagctagtcc cgtcactatg tgtaagtatt
     5341 tgttaccaac catcggacta atggcaatga gaaaaaagcc aacagccatt aaaaaagttg
     5401 ctccattttt ttctgtcatg caaggtcact cgctttttct ttattggcca aaatgacaaa
     5461 tggtgcccag ataaggaagg caacaaagag gttaaacagt gaaaccaaac ctgccataat
     5521 attacctcca gtagctaggt aagcataaag tccaacaggg gtaatccaag gtactgataa
     5581 gaataccggt ggaatcaaac ctattgcagt agcaaaataa gctatgctag cacaaattgg
     5641 tggcacaatt agccatggaa tcacaaaggt tggattcaaa acaattggca tcccaaatgt
     5701 aattggttcg ttgatattga aaacacccat tggtgcggac aatttggcaa tggttttatg
     5761 ctcttctcgt tttgagaata tgaagatagc aataatcaat gccaaggtta ctcctgaacc
     5821 acccatttga gcataagcat caaaggaccc gcgtgtccaa aggtatggta aattagcagc
     5881 gctatgcgct gtattgtaag cagctgtatt ttctgttaaa gctaccatat aaataccatc
     5941 catcactggg gctaagacat tatgaccatg caagccgaag aaccagagca gttgaactaa
     6001 gaaggttaac aagataactg aaccaatacc ctgtgataag cctagcaatg gtaattggat
     6061 ataggttgaa atgacatcac ttagggaaga acctgttaat gcgaagatga ggtaggcgaa
     6121 aattgccgaa gcgtaaatcg caactgttcc tggaataatg gcagcaaagg ctttattaac
     6181 cgcaggtggt acattatctg gtaaggtaat agtaatatta cgtttggtca aagccgcata
     6241 cacaaaactt gataaaaagc caataattaa agctgtgaac aagcctgtgg caccgacata
     6301 ctttagagct attgctcccc attgactagt ttcaatactt gaagctccac ccgcagtaat
     6361 gactgaaagc cccatttctt tcaaattgct aattaggtta gcagaggcat tttcaagtgg
     6421 tgtcgaaatg gttaaagtct gaggtagggt ggcaataaat gagccaaaag aaatcaatcc
     6481 tcctgccaat ggattaatct tatgcataac agctaaattg taaccgaaag caaaggcaaa
     6541 aaagagcgcc atgataccaa ttgtcccaaa ataaacatag ccattgatgt cgataacagg
     6601 ttgcatagct tttgcaaatc ctgtccatcc catattgttt ggaatatcgc gtaaaaaaac
     6661 gttcaataag acagcaactg aacctgccat ggtaataggc atcattgaaa taaaggaatc
     6721 acgaatagct actaaatgcc gttgtgaccc aatttttcct gaaatctcca taaacttatc
     6781 agaaaaatgc gacataaatc ttctcctctt tttatttttt taatgtaaca aaggtaacct
     6841 taaaagcagc ggtgtctgcc taacacaatt atctcaaaat catccttgtt aaacgtgatg
     6901 cttagagata accggtaatc ggctcttatc caaatgaacc cttctctctc attcaaggtc
     6961 tgtgaataat cttcacaaag acgatggttg ctgcaactgt ttagcatatt ggataagggc
     7021 tgctaactga gcttgagatt ggcgttctag gctttttttg aacagtttgc caacaataaa
     7081 ttgatttgct ttttgaaaaa tatctagagg atgatagtca taagaatagg taattctagt
     7141 ccgattctcc cccagagcct ctaattgata agccaattcc tttatcccat gattggaact
     7201 aaaacaagca gtatataatt gcggagcttc tagggccgta ataagcaccc tcactgtacg
     7261 ttctttgtat ttaccataat gtttaacata gtttatcccc gctttgatat catctcttga
     7321 caactgtctc aaggtatttt gtcgataatc ttcttggagc gatatcagca tggcttcaaa
     7381 acaatgatga atggaaacat ctccttctgc tgaaataatc atgactcacc tctttgtatt
     7441 gctgacattt tgtcgtaaac ggtaaccaat tccttggcta aatcaataaa ggctaaggca
     7501 gtcatcatgt gatcttgccc atgcaccatc aataaagaca attcaaccgc atcaccagct
     7561 gcttcttggg acagcaaatg tgtctgcgat ttatgggcaa tatttaacga gtttgtcgct
     7621 tcttgaagta agtgctgagc ctcctcaaac tgcccatctc gtgctgcatg aatagcctct
     7681 acagccttgc ccttggcttc gcctccatac atgattaagc ccataatagc ttctaagttg
     7741 gatggttccg tcatgcctac tcctccatca ttgctagggc tgtttcaagg actttttcac
     7801 cgttcataag accataatca gccatgttaa tggcatctac tttaatatct ggttcaaact
     7861 tatctttaaa atcctttagt aagaatttga cttgtggacc taacaagaga acgtcaatgc
     7921 tattagcagc cacttcgttg tcagcttcac tcacaggaac tgcccaaata gaaacttcaa
     7981 ggtcacgcgc ttgggctgct ttttgcatct tagtcaccaa catactagtt gacataccgg
     8041 cattacaaac taacataata gatttcataa ggtttctcct tttaatcgtt ttaatcatga
     8101 ataagtgggg taaacactgt catgaatttg gaataatttg gttcttctag taacgcttgc
     8161 tgaagctcca cctgattgac aaaagatgcc aaacctggtg atacatattt taacctatga
     8221 ttatgccctt tagacgggga taatagaaag acaaaatgaa cagcttgatg cgccttgtcc
     8281 cactcaagag gctctcggca aatagccact actacctgtt cagaataagt catgggatta
     8341 gcaggatgcg gaaaggcaag cacttctcca tagatgactg ggctgtaatt ttccctcagt
     8401 accatttgat gatagaagtc ctctacaaac gtttctgttc ccgcctcgtc aagacaagca
     8461 atcatccgta aaagcaagtc ttcctttgag attttctcgt ctaaataaag aaaacgatta
     8521 gggctaaaaa cacctgttag aagctgctct gcttttgcta aactcatctg tgtcggtaaa
     8581 ctgacctctt tcttgatacc ttcttgttct ccaataaatt gtcgaatagt ttcaatatcc
     8641 tgatttgaca aaaaaacact gacagtaatc actggtgtta aaaacatcag attggcaagg
     8701 ctgatagagg aaataatcaa atcaacggtt ttcagtcgct cttcggttat ttcatagtaa
     8761 ctgataacat cgacaatacg caaacgtcct tcaaattcct tttccaagcg atttttcaac
     8821 atcatggcac taccataacc tgtggcacaa actactagaa ccctcaattt atgacggttt
     8881 gaataacgct caatggccgc cattaaatgc aaactaatat aagcccattc atcatctgag
     8941 acatcattct tttgacatac aagcaaatcc gaaaaggtct gcttggtaag ggtaaatatt
     9001 tcaggatact ggcttttaat ttcctcagtt aaaggattag tcagctgaat atggttttca
     9061 agacgtgtgg tcaagggcat catgtgggct aataaacctt gaaataaatt ggtatctgtt
     9121 tctaaagtca tgcctgtcaa ttgactaatc ttggcaatac atgcttttaa atggtcctgc
     9181 aacttttcat cggtattatc atcttgccaa tgcttaccaa cagaatgttt gacctttaga
     9241 tgcagtgcaa tataattagc ctcctcttta ggaaaacgta tccccatcac ttcttccact
     9301 cgatacaaaa tgcgcagagc tacttgatac tcatcagact gacgaatagc tgttggaatg
     9361 gaaaacagtt ctaatggaca ccccgatcga atacgctgaa ccattagggc aatatgcaag
     9421 actagattat ttatgacaaa atcagaaagt ttcaacttag catcccgaca ttcatccaag
     9481 acaataatca tgatttctgc aaaattaata ccttcaagaa aggtattacc taccatggtg
     9541 gacaaggtat tatcaaaact agtaacaaaa aaatagtcca tgataaaatg cctaatgtcc
     9601 tcttctttac ctcttatttg aatatgttgg tgaattattt caagctctaa ctggtaaggt
     9661 attatgcgct ccttaatgcc tgctaaaaca tgttttaaag ttgtccgact gatatacaat
     9721 tcttgacaaa gctcttcaaa atcctgaacg gcatcttcaa aaaagaattt atgaagcaca
     9781 taatcttctc gatcaaccga ttcttccact tgagtcacat ctgccaaacg ttttttagac
     9841 gtcacacttt cttgccaaaa gatgtcaaat gccatagaat ggtcaatttc taagcagtaa
     9901 cctcgacctt gtttagaaat gatgtgagct ccgtgttcag gaaggctact gatcagttct
     9961 ttgaggtatt tcctaaccgt acggtcactc ataccaataa cctcagccag agttgcacta
    10021 gagacaaact gctctttgtg atggattaga aatgttatga tggccagttc tttttttgat
    10081 aacattagtc ctccttacta ctttggaaaa cgctttctaa cctcttttag tgtaccaaat
    10141 atttcctgaa aaaggtgacc atcattttcc gcattgattg tgaaaagaat ctatgatggg
    10201 gcaatctcca aacaaaattc ctgccaaggt cgcaaattat ctaacaaact aagatagtcc
    10261 tctctgacct cagcaaccac attagctttt gaactgaccg taaaattttt caaagcaatt
    10321 tgcagttctc ccttatatcg atgatagcgg tcattgtcaa taataatgct acctcgtttg
    10381 acctccttag attggtctct tggagcaatc gattcctgag cataaactag acgtggcatg
    10441 gttgatcgaa tcacataatc agatacatcg ccacgataac aatgcggata gccaatgatt
    10501 tgctcctcaa cttctgtcaa atcgatgata ggcctaacct tgatcgtcgt gactggtctt
    10561 gctaaagcct gagtacatgc tgccaattct tcttccgaaa tgaattggtt agatatgagg
    10621 atattatcaa tggttcctat cgctttcatt aattctactt gcaggccaat gggcaagtgc
    10681 ctatgctctt ccactgtcgg caagccttct gccagtagcc aaggaccttc agatgctgac
    10741 tgagcggtaa taaaagcagc cgtttcaata tcatgctcat gataaaaacg tgacatatcc
    10801 ttaaaatgtt gccatgacaa accggtaaat tcatgtggat aaaaattatg gcaaccaata
    10861 atattgctcc gttctgcatc tgtcgctagc aatgacatca ataattgttt atcagtgctc
    10921 atattaagtt caattttaag cccaaaggga tttcttgtta aagttacaat ctctgctaga
    10981 gggagagcct cgtctaagcg taagcccgct aacccgaagg catgagctcg ttcaataagc
    11041 tgatctgacc aaccagcttg gctaataaag cttggactaa cgtcagcaat cactcgaatg
    11101 cctaattgat ttgcataagc aatgagctct gcgtagcaat gaaacatctg gtgatcagct
    11161 ggtgccagct gtaagagact cataaacaag cgcttggctc catagctatg acataagtca
    11221 atataagctt tactcttggt aacatcatac cgctcagggt atagagaaaa tcctaaatca
    11281 accatattgc ctcctattta tcaaaaccat ttgactcgct caacgcctta aaccagtaac
    11341 ctgatttttt tatggttcgc ttttgactct ctaaatccaa agctaccaaa ccatatcggt
    11401 ttttataagc atttaaccaa gaccagcaat caataaaagt ccacaagagg tagcctttgc
    11461 agttggctcc ttctcccaaa gccttatgaa gctggataag atgatcctcg ataaaggtga
    11521 tgcggtagtc atcttgtatc tggccatctg ctaaaaaagc ttcttcacct ttgacaccca
    11581 taccattttc cgtgactagc cattcgatgt taccatagtg ttcttttaaa ttaagagcaa
    11641 tatcataaag tcctggttca taaatttccc aaccccggtg aggattgact tttttaccag
    11701 gcatatcata aggttcaaaa taaatatcta agataagggg gtccccctct tgctgtgact
    11761 tactaggtgc ctgaacccgc aaaggctgat aataattaac tcccaaaaaa tcaacagtat
    11821 tgtttttgat aatctctaat tcatcagcac tatattgagg taataaatca gcttcctcta
    11881 aaatggaaac taactctgct gggtaaatac ccaaaactga tggatctagg aaggatttgg
    11941 tttgaaaaag ctctgcgatt ctagcagcct tgacatcttc aggagcatta ctccgaggat
    12001 aagcaggtgt catgttaagc acaatactaa tcttgtggtc gggatgaagc ttatgacaag
    12061 ctttgaccgc cagtgaactg gccagttgtg tgttgtaagc cacttgaact gctgccttgg
    12121 catctacttt acaagggtag tgataataac ctaaatagcc acattcgact ggaacaatcg
    12181 gttcattaaa ggtaatccaa gtgtttacta aatcaccaaa aagctcaaaa caggtttttg
    12241 cgtaggtttc ataagcccag acagtagctt tgttttccca gccacctttt tcttgcaagg
    12301 cataggggag gtcaaaatga tagaggttaa caatcaattt aataccttga gcaataatgt
    12361 cttgaaatac ttctcggtaa aatgtcaccg cctttggatt aacctccccg actccttctg
    12421 gaatcaatcg agaccactgg attgaggtcc gaaaaatcgt gtggcctgtt tctttcaaaa
    12481 gggcaatgtc acccttatag ttttcataaa aggttgaggt tttttctgga ccaatttggt
    12541 gatgaaactt agctgactca atactaaacc agtaatccca gttgctaggt cctttgccat
    12601 ctccaggaac cgttccttcg ctttgaggcc cagatgtgga acttccccat aaaaagccat
    12661 ctggaaattg ataacggtgt tttctttgtt tcatatcctt tgtcctttct ttgctcactt
    12721 ctctttttat tataagaaga aaaacaggtg atgtaaacgc tttaaaaaat ctgttttttc
    12781 cttatcatca cggaaaataa gtgatttaaa gcttgacata ttttattatc ttaaagagcc
    12841 tatctaacct gccctgctac ttcttatcaa aaccaagccc ctattgacag atgccttagc
    12901 ctatgtttga ataggggtat ggcttattta aactacttta caaaaaccga gtgggcactt
    12961 tggttaagct ctgtcttggc cattttaatt agcgcccttt tattcggtaa gcaagctccc
    13021 ttagctttaa tagcttcttt gattggtgtg acctctctca tttttagtgc taaagctaat
    13081 cctattggtc aagggctcgt cattattttt tccattatct atgcctatct ttcattacga
    13141 aacagttact atggagagtt aatgacctat cttttcatga ccctccctat gactattttt
    13201 tcacttttta cttggttaaa ccatcctttt gaagggaaaa aatcacaagt gactatttca
    13261 cgattaacac ccactgatcg aagatgtctt ttcgttttta ctatactggt cactcttatt
    13321 ttctacggca tcttggcttc tattcaaaca gcctatttac ttgtctccac tttatcgatt
    13381 gccacttctt tctcagccgt ttatctcagt tataagcgta gcccttattt tgctttagca
    13441 tacgggctca atgatctagt cctcattctc ttatggatgc atgctgctca aacagattct
    13501 agccaatatg cagtagtcat ctgctttgcc acctttctta ttaatgatag ttacactttt
    13561 tatagttggc taatgctcca acgttaccaa gaaaaaaagg tcaaaaaagg atgagggcct
    13621 aagcctcatc ctttttcaat ttttcacgtt ctaagcgcaa acgtctattg ggatttaaaa
    13681 gattaaacaa ttcttctaat ttctcagcat tccaaacatc tgctgccgat acaaaatttc
    13741 catccttatc cttaaaggat atcggtttat cacccataat cagaaacctc catcttaaag
    13801 ataaaacaca aggttgctat ggcaatgcca tttctaaaga ccacattaat ccacaaattc
    13861 aaattcaaat ttgccaatac gaacaagatc cccgtctttt gctccacgtt cacgaagggc
    13921 ttcgtcaacc cccataccgc gcaattgacg ggcaaatttc atgatggatt cgtcacgttc
    13981 catattggtc atgacaaaga gacgttctaa cttctcacca gacaagaccc aagtagcgtc
    14041 atcgtcacgt gtgatctcaa attctttctc agcctcagca aaaccatagt aagcttcctc
    14101 gtccaccaga tcagattcat catacaataa gaattcatcc gtcttagcaa gtaattctgc
    14161 cgttgcttct aacaagttct ctaagccttg atgtgctagg cttgaaatag ggaaaatcat
    14221 tggcaaatca tcaaactcgt catattgggc agccaatttt ttcttgaagg ctttcaagtt
    14281 ttcttgagcc tctggcatgt ccattttatt agccacaata atctgtgggc gctccatcaa
    14341 tcgcaaatta taggtttcca gctcgttatt aatggaaaca taatcttcgt aaggatcacg
    14401 accctcacta gcagacatgt caatcacatg aagaataacc cgtgtccgct cgatatgacg
    14461 gaggaattga gttcctaaac caaccccttg gctagcacct tcaatcaaac ctggcagatc
    14521 tgccatagca aagctatcac ctgactttgt acgaaccatt ccaagattag gaacaatagt
    14581 ggtaaaatga taggcaccaa ttttcggttt agctgatgac acaacactta acaaggttga
    14641 tttcccaaca gatgggaatc cgaccaagcc aacgtcagct aagattttga gttctaactc
    14701 taactgacgt tcctcacctg gctcaccatt ttcagcaatc tctggcgcag gattacgagg
    14761 agtagcaaaa cgaatattcc cacggccacc acgaccaccc ttagcaatga ccacttcttg
    14821 accatgttct actaagtctg taattacttt tccagtttca gcatcacgaa ccgttgtccc
    14881 ttgaggaaca aagacaatca aatcttctgc accacggccg tgcatgcctt tggtcatacc
    14941 tttttcacca gatttcgcct tgaatttacg attataccgg aaatccatca aggtacgcaa
    15001 accttcgtcc actcggaaga taactgagcc acctttaccg ccgtctcctc cccaaggacc
    15061 gccatttggg acgtactttt cacgacgaaa agctaccata ccatcgccac cacggcctgc
    15121 ttggacactg atttttgccg tatctaaaaa catactcata ctttttttat tctctaactt
    15181 tcttttactt taaaaaaacg cctttcagcg tttccttaca ttaatactga tagggcactc
    15241 gcaataagcc cgccaacagt tacaagaacc attaggataa caacaaacat tgttactttt
    15301 tcaaaggttg tttttttgcg aggtccattt tctccaaatg ccacgttaaa tacctcatct
    15361 attgattttt cttcttatat attaacatga aagatcgttt taggcaaata ccagatgaat
    15421 atttacgcta tgtagactat tactgagtat tgtatcttgt gaatttcata tgaatatgat
    15481 acattagcat ttgcaaaata atgttacaga taaaaacctc ctcgtctggt gaactgcacc
    15541 ccaaaagtta gacacaaaat ctaacgattg gggtgctatt tttttatgaa atttaatcaa
    15601 gaaacgaaag ttaagattta tgagttatgg caaatgggag agtccattaa atccatatca
    15661 aaaaagtttg atatggcaga atccgatctc aaatatatga ttcgcttgat tgataggtat
    15721 ggggtaacca ttgttcaaaa atgtaagaat cattattatt ctctagaact gaagcaagag
    15781 ataataaata aagtcctgat tgacggccaa tctcagaaac aaacatcctt agattatgct
    15841 ttaccaactt ctagtatgct ctcaaggtgg atagcgcaat acaagaaaaa cggttatact
    15901 attcttgaaa aaccaagagg gagaccgagt aagatggggc gtaaacgtaa gaaaaatttg
    15961 gaagagatga cagaggttga acgtcttcag aaggaattag aataccctag agcggagaat
    16021 gctgtgctaa aaaagctgag agaataccgc ttgagggacg aagtaaagct caaagagcaa
    16081 cagaaatcat tcaagcatta aggaatcaat ttcccttaga gatgctactt gaaatccttg
    16141 atttatcacg ctccacctat tactatcaag tgaagcgact agctcaagga gataaggata
    16201 tagaactaaa gcatgtgatt cgagagattt atgatgagca taaaggtaat tacggttatc
    16261 gtcggattca tatggagttg cgtaaccgag gatttgtggt caatcataag aaagttcaac
    16321 gtctcatgaa agtcatgggc ttagcagccc gcattcgtcg gaagcgcaag tattcttctt
    16381 acaaaggaga ggttggtaag aaggctgata atctgattaa acgtcacttc gaaggctcta
    16441 aaccttacga aaaatgttac actgatgtga cggagttggc cttacctgaa ggaaaactct
    16501 acttatcacc tgttcttgat ggctataaca gtgagattat tgatttcact ctatctcggt
    16561 ctcctaactt gaaacaggtt caaaccatgc ttgagaagac ttttccagcg gattcataca
    16621 gcggaactat tcttcatagt gaccaggggt ggcaatacca acaccagtcc taccatgatt
    16681 ttttagagtc taaaggtatt ttgccatcca tgtcccgcaa agggaatagc ccggataacg
    16741 gcatgatgga ttccttcttt ggcattctca aatctgaaat gttttatgga ctcaagacaa
    16801 cttatcaatc acttgacaag cttgaagaag ctattacaga ttacattttt tactacaaca
    16861 acaaacgaat caaagcaaaa ctaaaaggat ttagtcctgt ccaatacaga actaaatcct
    16921 ttcaat
//
LOCUS       DAUGSW010000030        16832 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUGSW010000030 DAUGSW010000000
VERSION     DAUGSW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16832
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.030"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..381)
                     /locus_tag="VIB18_001247"
     CDS             complement(<1..381)
                     /locus_tag="VIB18_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4238 domain-containing protein"
                     /protein_id="HEQ8766253.1"
                     /translation="MTKKVMTKKQHYYPRCLLKHFADVHGKVNVYIRQANKVSKINYE
                     KLCASNFSYESDDVVDNILENKLGVYEAKMGSIIDYILKNITSPDFTVTKEQQKFLYQ
                     YMWLQYIRTDAGRINFMNMFANTFS"
     gene            complement(548..697)
                     /gene="rpmG"
                     /locus_tag="VIB18_001248"
     CDS             complement(548..697)
                     /gene="rpmG"
                     /locus_tag="VIB18_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8766254.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(713..895)
                     /gene="rpmF"
                     /locus_tag="VIB18_001249"
     CDS             complement(713..895)
                     /gene="rpmF"
                     /locus_tag="VIB18_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEQ8766255.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            1115..2395
                     /locus_tag="VIB18_001250"
     CDS             1115..2395
                     /locus_tag="VIB18_001250"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEQ8766256.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRSAYRQALIDYLTPMRDQLSKDSQRRLNENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKAMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGLALPIETEMDVYLA
                     VLGDSANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            2733..4481
                     /gene="aspS"
                     /locus_tag="VIB18_001251"
     CDS             2733..4481
                     /gene="aspS"
                     /locus_tag="VIB18_001251"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEQ8766257.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSDAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            4474..5415
                     /locus_tag="VIB18_001252"
     CDS             4474..5415
                     /locus_tag="VIB18_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8766258.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            5435..6313
                     /locus_tag="VIB18_001253"
     CDS             5435..6313
                     /locus_tag="VIB18_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8766259.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGVLSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            6356..7228
                     /locus_tag="VIB18_001254"
     CDS             6356..7228
                     /locus_tag="VIB18_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8766260.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(7255..7563)
                     /locus_tag="VIB18_001255"
     CDS             complement(7255..7563)
                     /locus_tag="VIB18_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8766261.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKACHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(7651..9342)
                     /locus_tag="VIB18_001256"
     CDS             complement(7651..9342)
                     /locus_tag="VIB18_001256"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEQ8766262.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFTKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWHWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            9633..10070
                     /gene="argR"
                     /locus_tag="VIB18_001257"
     CDS             9633..10070
                     /gene="argR"
                     /locus_tag="VIB18_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8766263.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            10067..10419
                     /locus_tag="VIB18_001258"
                     /pseudo
     CDS             10067..10419
                     /locus_tag="VIB18_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            10406..12961
                     /gene="mutS"
                     /locus_tag="VIB18_001259"
     CDS             10406..12961
                     /gene="mutS"
                     /locus_tag="VIB18_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEQ8766264.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQESGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPP
                     QVESSSAVRQGQLSLFGDDEKAHEIRQALEAIDVMNMTPFQAMTTLYELKKLL"
     gene            complement(13359..13979)
                     /locus_tag="VIB18_001260"
     CDS             complement(13359..13979)
                     /locus_tag="VIB18_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766265.1"
                     /translation="MKKKLMLAMTLLTVSVATNVKADTSATTLVQNKFILDGPQQKVK
                     QVTVSDFAVGDSEIKVRLPQAWSVKVSRESNQTPDKEQKPSSNQSENKEGNFSKRLPY
                     NTQHTIKLSSQLKKGEKVTFTFKDEDFWGAGYSFYRDSASIEEDKQYDEEIKKIEEEL
                     EKRDQEDDALKLFKQQQQEEANKTWYQRVGDSFQDQWWNFKDWLRG"
     gene            complement(14187..14570)
                     /locus_tag="VIB18_001261"
     CDS             complement(14187..14570)
                     /locus_tag="VIB18_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEQ8766266.1"
                     /translation="MSKKNAIRKLKEFHRWQRIANSLGLSYNELYQFDIEYHPTRRKH
                     LEISRECALEELDAIKFAINQLSKIEYRQILIECYLISEKKPQQDIIAELNRSQSWYY
                     ETKKRALLEFSENYRGGALKNNIRL"
     gene            complement(14545..14907)
                     /locus_tag="VIB18_001262"
     CDS             complement(14545..14907)
                     /locus_tag="VIB18_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ8766267.1"
                     /translation="MSAKEQLKELKLLFALITLFEEQRDKDIKLINAFHNPEAIRHIE
                     KGTAKKLLYLAKERDKRLAMIATLQDERQIAVIKARYVDGLSWDEIPDKLGHSRNTVF
                     KLHREALEVLDEQEERYS"
     gene            complement(15311..15799)
                     /locus_tag="VIB18_001263"
     CDS             complement(15311..15799)
                     /locus_tag="VIB18_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766268.1"
                     /translation="MLELSIENIIKSMKTQGKTRVTGSIGDQAIRIDLDGLVIHYNGQ
                     GLLLETIPGTYGGKRYFFVCPDCERRCRKLFKASHAFACGSCQKIHQATLNRSKTDCC
                     YYWQLAFKECLKVNPEARHIHGYYSRDDFPKRPKYMRLTKYLYHWRRFHYYMDKGDRY
                     WL"
     gene            complement(15873..16382)
                     /locus_tag="VIB18_001264"
     CDS             complement(15873..16382)
                     /locus_tag="VIB18_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766269.1"
                     /translation="MRTFSDTPKTFTFHYTFKDFDTAQVACHAILGYMTGTYEQPVID
                     ATYHNDDQGGRANQLVLKYAEDRKLNKVFKRICDSFKDYYNQPEDMTDEELDHQRVVS
                     LSKSTQGKVNNRATLIAFISDQNQLAEHLSMNYKEMTPEDLGAILESISQAFNHLYDM
                     VVEGQLLVK"
     gene            complement(16384..16557)
                     /locus_tag="VIB18_001265"
     CDS             complement(16384..16557)
                     /locus_tag="VIB18_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766270.1"
                     /translation="MKLKLHTRGGNTITIQGDRTLYDELIKYLLSGQQPNWVACPSAI
                     INLSDIIAITKEK"
     gene            complement(16563..16736)
                     /locus_tag="VIB18_001266"
     CDS             complement(16563..16736)
                     /locus_tag="VIB18_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2758 domain-containing protein"
                     /protein_id="HEQ8766271.1"
                     /translation="MKIKLFYQKHNESLDDFEYRVNLFTLSVSVIDIKFQEATYGNYE
                     DMDSRTGLLVLYR"
BASE COUNT         4879 a         2949 c         3504 g         5500 t
ORIGIN      
        1 tgaaaaggta tttgcaaaca tattcataaa atttatacgt ccagcatcag tccttatata
       61 ctgtaaccac atgtattggt ataaaaactt ttgttgctct ttggtaactg taaaatctgg
      121 agaagtaata ttttttaaga tataatctat gattgaaccc atttttgctt cataaacgcc
      181 aagtttattt tctaaaatat tatcgacaac atcatcgctt tcatatgaaa aatttgaagc
      241 acaaagtttc tcatagttta ttttagagac tttgttagct tgtcgtatat agacattcac
      301 tttgccatga acatcagcaa aatgttttaa tagacatctt ggatagtagt gctgtttctt
      361 tgtcatcacc ttctttgtca ttaaaactat acctctttaa caattaatta tactacaata
      421 attatatcaa aaaactacta tatctacagc acgaagaaat tttaatcagt taaaaataag
      481 ttcttctgct aaaaccaaaa gaaaaaagcc tttgaaacgt tcatttcata ggcttttctt
      541 atcttgatta ttttacttct gtaaatgtaa cgtgtttacg taattttggt gagtattttt
      601 tcaattgaag acggtctgga gtgttacgtt tgttttttga agtaaggtac aagcgttcac
      661 cagattcttt atgttcaagt gtaatattta cgcgcatggt atctcccttc tattatttag
      721 cttcgttagc tttagcgatt ttacgtcctt tgtagtatcc tttaagggat acacggtgag
      781 aacgtgagta atctccagta gtttcgtcga attgtacaga tggagctgtc aatttgtagt
      841 gtgtacgacg tttgtttttc ttcgcttttg acgtgtgacg tgcaggtact gccattttat
      901 tgttcttcct ttcgatgtgt aagttttgat tttcatcaac ttcactatga taacatatct
      961 tttttgtaaa gtaaagttac ttgacaaaac tttttatttt tacaatttca tggtgaaaat
     1021 actatcaaac taaagcaaat gatatatgct tgtttaaaat ataagaaaaa atggtagaat
     1081 gtttaaagag aaaactaatc aaagaggtaa acttatgaaa cttcaaaaac caaaaggaac
     1141 ccaggatatt cttcctgggg atgctgcgaa atggcagtat gtggaatctg ttgcgcgtga
     1201 tacgtttagc caatataatt atggagaaat tcgtactcct atgtttgaac actacgaggt
     1261 aatctcgcgg tctgtaggtg atacgactga tattgtgacg aaggaaatgt atgatttcta
     1321 tgataaagga gatcgtcaca ttaccttgcg accagagggt acagctccag tggtacgttc
     1381 ttatgttgaa aataaattgt ttgcgccaga ggtccaaaaa cctgtcaaac tttattatat
     1441 cggttccatg ttccgctacg aacgccctca agctggtcgt ttacgtgaat ttcaccaaat
     1501 tggagtagaa tgtttcggtg ctgctaatcc agcaacagat gttgaaacca ttgcgatggc
     1561 ctatcacctc tttgaaaaat tgggcattaa ggatgtcacc cttcatttaa atagtttggg
     1621 gagtcctgag agtcgttcag cttatcgtca agccttgatt gactacttaa caccaatgcg
     1681 tgatcaatta tctaaagata gtcaacgtcg cttgaatgaa aacccactgc gcgtgcttga
     1741 ttctaaagaa aaagaagata aactagccgt tgaaaaggcg ccttctattt tggattactt
     1801 agatgaggaa agtcaggcgc actttgaggc agtcaaagct atgcttgaag cacttgacat
     1861 tccttatgtg attgacacca atatggtgcg tggccttgat tactataacc acactatttt
     1921 tgaattcatc acgtctgtgg agggttctga cttaactatc tgtgcgggtg gacgttatga
     1981 tagtttggta ggttattttg gtggaccaga aacccctggc tttggctttg gtcttggttt
     2041 agaacgtctc ttgatgatta ttgaaaagca gggtcttgcc ttaccaattg agacagagat
     2101 ggatgtttac cttgctgtgc taggtgatag tgctaatagc aaagctttag aattggttca
     2161 agccattcgc cgtcaagggt ttacagctga acgagattac cttggccgta agattaaggc
     2221 tcagtttaaa tcagccgata cctttaaagc aaaattggta atgactttag gagaaagtga
     2281 agttgaagca ggcaaagctg tgattaagaa taatcgtagt cgtcaagaag tggaagtcag
     2341 ttttgaagat atgatgacaa actttgcaaa catctcagag caattattat cttaatgatt
     2401 ttattgtcgt cataagcttg tgttgatatg attgtttaga agataatcac taaaacaggt
     2461 gtaacttctc tttttagaag ggagttgcac ctgtttgttt tctgtaaggg gattgattag
     2521 ctttcttagt attctgtgag gacacctgat atgtcaaaat actgacggct cagtattctt
     2581 gctttatctt tagaaaaact ctttttaaat gggtggggtt tttaagggct ttttgctata
     2641 atagtaggga atgaattaat tgatttatat agtgaaagga attggaaacg agcaggtttc
     2701 acaggattct gtttgtttta gggaatttat ttatgaaacg tagcatgtat gcagggcgtg
     2761 ttcgcgaaga acacattgga acgacaatca cattgaaagg atgggtcagt cgtcgtcgtg
     2821 acttgggtgg tctcatcttt attgatttgc gtgaccgtga gggtgtgatg caattagtca
     2881 ttaaccctga ggaagtttcc agtgatgtga tggcaactgc tgaacgctta cgtagtgaat
     2941 atgtgattga agtggaaggt tttgttgaag ctcgacaaca agccaatgat aagttggcga
     3001 caggaatggt tgagttaaaa gtatctgctt tgaccatttt aaacacagct aaaacgacgc
     3061 cttttgaaat taaagatgac gttgaagtaa gtgacgacac gcgtttacgt taccgttact
     3121 tagatttacg acgtccagaa atgttagaaa acttcaagct acgtgcaaaa gtgactcatt
     3181 ctatccgtaa ttaccttgat gaccttgagt ttatcgatgt cgagacacct atgttgacaa
     3241 aatcaactcc agaaggtgcg cgtgactatc tggtaccaag tcgtgttagc caagggcatt
     3301 tctatgcttt gccacaaagt ccgcaaataa ccaaacagtt attgatgaat gctggctttg
     3361 atcgctatta tcaaattgtg aaatgtttcc gcgatgaaga tctacgtggt gaccgtcaac
     3421 ctgagtttac acaagttgac ttggaaacgt cattcctttc tgaacaagaa attcaagaca
     3481 tcgttgaagg catgattgct aaagtgatga aagagacaaa agaaatagat gtaaccctac
     3541 cattcccacg tatgagctac gatgtagcaa tgaatagcta cggctctgat aaaccagaca
     3601 cacgttttga aatgctttta caagacttga cagtaactgt caagggaatt gacttcaagg
     3661 ttttctcaga cgcaccagct gtcaaggcga ttgtggtaaa gggaaatgca gatcgatact
     3721 ctcgtaaaga tattgacaaa ttaactgagt ttgccaaaca atttggtgct aaaggccttg
     3781 cctgggttaa ggtgacagat ggtcaattgg caggcccagt agccaagttc ttgacagcta
     3841 ttgagacaga gttgtcaagc caattaaaac ttgctgagaa tgatttggtt ttatttgtag
     3901 cggatactct tgaggttgct aataatacat taggtgccct tcgtaatcgt attgccaagg
     3961 accttgacat gattgatcag tcgcagttta atttcctttg ggtggttgat tggccaatgt
     4021 ttgagtggtc agaagaagaa ggacgttata tgtcagctca tcaccccttc actcttccaa
     4081 cgccagaatc tgctcatgag ttagagggtg atttggctaa ggtacgggct attgcttacg
     4141 acatcgtttt aaatggttac gagcttggtg gtggtagcct gcgtatcaat caaaaagaga
     4201 tgcaagagcg catgttcaag gctcttggct ttaccgctga tgaagctaac gaccaatttg
     4261 gtttcttact agaagcgatg gactacggct ttcctcctca tggtggcttg gcaattggtc
     4321 ttgaccgttt tgtcatgttg cttgctggaa aagacaatat tcgagaagtt attgccttcc
     4381 ctaaaaataa caaagcctct gatccaatga cgcaagcacc tagtcttgtt tctgaaaacc
     4441 aattagaaga actcagtctt caaatagaaa gtcatgatta agaaaacaac ctataagaaa
     4501 aaagttaaat atgtcattag tagaggggcc aagaaagttg gcctactcca cgctctaaga
     4561 agtatttcaa gagaaaaata tgcagagaag atttcggctt ctctgcttta tggcattctc
     4621 tctagtattg ctgtgaattt tttcttccag cctgggcatg tttattcaag tggagcaact
     4681 ggtctagcac aggttttttc agctcttagt catcgtcttt taggctatga ttttcccatc
     4741 gcctttgcgt tttatttgat taatattcct ttgcttattt tagcttggta taaaattggg
     4801 catcaattta ccatttttac ctttatcaca gtcagcatga gttctttctt tattcaaatc
     4861 atgcctcaag tgacgctgac gactgatcct cttatcaatg ctatttttgg tggtttggtt
     4921 atgggaatgg gaattggtac aggtctcaaa tcacgtatct ctagtggggg gactgatatt
     4981 gtcagtttga cccttagaaa acgaacaggc aaggatgtgg gcagtctctc attgatggtt
     5041 aatggtgcaa ttttagcctt tgcagggatt ttatttggct ggcagtacgc cctttattct
     5101 atggtctcta tctttgtatc aagtcgtgtt acggatgcca ttttcaccaa gcaaaagaaa
     5161 atgcaggcaa ctattgttac cagccatcca gagcgtgtga ttcatatgat ccataaacgt
     5221 ctgcatcgcg gggtgaccag tatcaacgac gcagaaggga cttacaagca tgaacaaaaa
     5281 gcagttttga ttaccatttt gacatgtgaa gaatacccag aattcaaatg gctgatgtta
     5341 aaaacagacc cacaagcctt tgtttcagtg gctgagaatg ttagaattat cggtcgtttt
     5401 gtggaagatg attaagaaaa acacaggagg tgtcatgtca attgaccaac gtttacagtt
     5461 aaagaaattt tgctttatta ttttaggagc tgctatctac gcctttgctt ttgtttattt
     5521 ttacatggct aatcgcattg cagccaatgg tttagctggt ctcaccctag ttggtaaggc
     5581 actttttgag attgatcctt ctttgatagg ctatttgatt aatttgcctt tggtcttgct
     5641 gggagctaga tgttttggga aaagagccat ggtttacaca gtaacgggtg ttttatcact
     5701 ttactttttt gtgtggctgt ttcaacgctt tcctttggtc gttgacttgg accatgacaa
     5761 tttagtcgtt tccttgatgg ctggaattat tggtggtcta ggtggcggtc ttgtgtttcg
     5821 caatggtgga accatcggtg gagcagatat tattgctaag ttattagaag acaagttagg
     5881 actacagctg aatcaagctc ttttaggcat tgatcttttt gtcatgattg tctctttgac
     5941 ttatatttcc ctgccgcaaa tgatgtatgc tctgattgct agctttatgt atggtcaaat
     6001 tgttcgcttg gtacaacaag gtggttattc agcccgaggc atttttatcg tttcagaaca
     6061 agcggagaaa attgcccggt tcatcatgga cgaattggga agaggagtta cttatctaac
     6121 aggtgaagga gcctactctg gtcgccgtaa aaaagtgatt tatgtggctt tggggcgaag
     6181 agatattagg gaattaaaag cttttttaac tcaggttgat cccaatgcct ttatcactta
     6241 ttttgatgtt aatgaagtca atagcccaga atttttaact attaaaagca aataccataa
     6301 aaagagaaaa taaatgagca ttagagttgc ctgcgaagaa tagtgaggat taaggatggc
     6361 acatcacgat aaattgacta aactactaaa actgtttttg attgccctag gtgtagccat
     6421 ttataccttc ggttttgtta attttaacat ggctaatgct ttggctgaag gtggtgtggc
     6481 aggaataacc ttgattttac acgcgcattt tgggattaat cctgcttact cttctctctt
     6541 atttaatctt ccacttttta ttttaggggc aaagattttt gggaagcgtt ctttggctct
     6601 aaccatctat ggaacagttc tgatgtccgc ttttatctgg atgtggcaaa aagttcctat
     6661 cgaacttggt ttggaaaatg acatgatgtt ggtggctgta gtggcaggtc tcttttcagg
     6721 gattgggagt ggcattgttt ttcgctatgg tgcaaccaca ggtggaacgg atattattgg
     6781 tcgcattgca gaagaaaaat ttggagctaa gctaggtcaa actttgcttt tggtggatgc
     6841 tcttgtattg acagcttcgt tgacttatgt ggatttaaaa cacatgcttt atactttggt
     6901 ggcaagcttt gtttttagcc aaatgattag tgtggttcaa aatggtggtt acactatccg
     6961 tggaatgatt attattacca agcattcaga ggctgccgct caagctatcc taaccgaaat
     7021 caatcgtgga gtgacttact tgaaaggtca aggagcttac tctggtaatg attacaatat
     7081 catgtatgtg accttgaacc caactgaagt tcgggaagtc aaacgtattt tagctggttt
     7141 ggatccagat gcctttatct ccattattga tgtggacgaa gttattagct ctgattttaa
     7201 aattcgccga agaaattatg ataaataaaa atacaggtca aacagcctgt atttttattt
     7261 tggtccccca cttaagaaac taccaagcat aatagctgat atagcagttc ccttgtaatg
     7321 gcaagctttt gtttttacca agcgactaag atcaaatatg cttttaggag catcaaattg
     7381 atgtgttaag atgtattgat tgataagtga gtcaattttt gtagctagga gtgagctcat
     7441 cccctctttt tcaagttgac tggcgagctc gaagatcgct tgacgaaaat aatcatcggc
     7501 ttgtattact tgttcgctat aaactttact aagagcatct aatatttctt tttctgatgg
     7561 catggcattc tcctgtaaca tattgtgcta ttattataat ataaaaaact aagactgtca
     7621 taaatgtgac agccttagta attttattac ttacatttca tttggtgcgt caacaccgag
     7681 taagcgaagc gcttctttaa gaacagtagc agttgcatag cagagagcta agcggttatc
     7741 acgttctgag ttgtcgtcaa gaatgcgagt gtgagcataa tatttgttaa agctttgggc
     7801 taagttaata gcaaatttag ccataataga aggctcaaag ttatctgatg ttcgcttgat
     7861 aatgcgtggg aaatcttgga taagtttgat aatttcccag ctttcagcat cagctaaact
     7921 gtaagtggtg gttgcagatg gcgtaaagtc agctttacgt agaatagatt ggatacgagc
     7981 atgagcatat tgaacgtaag gtccagtttc tccttcaaag gaaaccatgg cttcaaggtc
     8041 aaagtcatac ccattcatac gatctgtttt gagatcgtaa aacttgatgg caccaacacc
     8101 aacggcatgg gcaacggctt ctttgtcagc aaggtttgga tttttcgctt caatttgaga
     8161 agctgcacgg ttaatggctt cagcaaccgt aggttcaaga agaataacat tacctttacg
     8221 tgttgataat ttagcaccgc cttttgtgac aagtccaaaa gcaacgtgtg tcatatcatc
     8281 tgaccaatcg taacccattt cttttagcac tgcttttaat tgtttgaagt gagcagcttg
     8341 ctcattacca acaacataaa cggatttagc aaagtcataa gtgcgtttac ggtaaagtgc
     8401 ggcagctagg tcacgggtaa tgtaaagagt agcgccatct gattttttga tcaaggcagg
     8461 gtgttcaatg ccatattttt caagattaac aacttgggca cctttggatt ctacaagaag
     8521 gtttttcgct tctaatagct caagaacctc atccatttta tcattataga aggcttcacc
     8581 gttgtaacta tcgaaggtga catgtaattg gtcataaaga cggttaaact caagcaaact
     8641 ctcgtcacgg aaccaatgcc ataattcagt agcttctttg tcgccatctt ccaatttacg
     8701 gaaccattca cgagcttctt catcaacggt gggatcagtt tcagcttcag cattgatacg
     8761 aacgtaaagt tttaagagtt catcaatagg atgtgcctga acagcagctt catctcccca
     8821 ttttttgtag gcaacaatga gcataccaaa ttgtttaccc cagtcaccaa ggtgattgat
     8881 ttttacaggt ttatagccca ttttggtaaa aatgtgagcg agactatcac caataactgt
     8941 tgagcggagg tgaccgattg aaaatggctt agcgatgttt gggcttgaca tgtcaatagc
     9001 aacatttcgc ccttgacctt cgtcttgctg agcatagtct gaacctgctg taatcacttg
     9061 ttcaaggacc tgtgaggaaa tcttagcttt atcaaggaaa aagttgatgt aagggccgac
     9121 agctacgact ttttcaaatt ggctctcatc aatctgttca gctaactcgc tagcaatcat
     9181 ttgaggggct ttgcgaagga cttttgctaa gctaaaagct ggaaaggcaa ggtctcccat
     9241 gtcagaattt tttggggttt caagcaagtt aaaaatagca tcttgttcta attctggaac
     9301 aactttagct atttcacttg cgattagagt tttagtatcc atacagcgtc tcctaaaaat
     9361 tgtttgtcac cctattctaa catatttctt taaaataaac gaggagagga ttgataaatt
     9421 atactgaaac tttcaaggaa atgaattgct tgaggttgtt gtttttctga aaatgttata
     9481 aaaagagaaa tgaggtttct tttcaacagt tttcaagtga aattctagtt gaatttgata
     9541 aaaaattgct gaaaatagct gggcgaagat gaaataatac actttttttg ttataatttg
     9601 agaggataat tatacaattg gggtgatata tcatgaataa aatggagcgt caacagcaga
     9661 ttaagcgaat cattcaagca gagcatattg gcacacaaga agatattaaa aatcaccttc
     9721 aaaaagaagg cattgtggtc acccaagcaa ctctatctcg ggacttaaga gaaattggcc
     9781 ttttgaaatt gagagatgaa caaggcaaac tctattatag tttgtctgaa cccgttgcaa
     9841 caccatttag tcctgaggtg cgtttttatg ttttgaaagt tgatcgagca ggttttatgc
     9901 tggttctcca taccaattta ggagaggctg atgttctagc taatttgatt gacaatgatg
     9961 ccattgaaga tattctagga accattgctg gtgcggatac cttgcttgtg atttgcagag
    10021 acgaagagat tgctaaacgc tttgaaaaag atttggctgc aggcctatga ctagctatta
    10081 agaatctttg acacaattga ttcttgctat ccatgaattc tagtatcgtt gcttataaag
    10141 aagtgaagca atagctgtct aagctccatg attttaaaaa gtaagcttat cagatgaaac
    10201 gctatcaaca agatgccctg cttttcaaaa aaaatagata aagaaaaggc tgcgacagta
    10261 tctgcaagca gggcaaaaga actagaagat aggctcagtc atcagccatt aattgatgat
    10321 tatcgagaaa agatgcaaga tgcaagtgat gtgattcagt atatcaccaa acgtatagaa
    10381 gatcagttaa acaaggagtt aacaaatggc aaaaactaac atttctcctg gaatgcaaca
    10441 gtatctggac atcaaaaaag attatccaga tgcttttttg ctttttagga tgggtgactt
    10501 ttatgaatta ttttacgagg acgctgtcaa agcagcacaa ctcttagaaa ttggtttgac
    10561 cagtcgcaac aagaatgcgg aaaatccaat tcctatggca ggcgtgccac atcattctgc
    10621 ccaacaatac attgatgtgt taattgagtt gggttacaag gttgctgtcg cagaacaaat
    10681 ggaagaccca aagcaagctg ttggggtggt gaagcgtgag gtcgttcaag tcataactcc
    10741 tggaacggtt gtggattcag ctaagccaga tagcgccaat aactttttgg tagctgttga
    10801 ctttgatggt tgccgttatg gattggctta tatggatgta tccacaggtg aattttgcgt
    10861 gacagatttg gcggacttta cgagtgttcg tagcgaaatc caaaacctca aggcaaaaga
    10921 agtcttacta ggttttgatt tatctgaaga agaacagacg attttggtca agcagatgaa
    10981 tttgctgctt tcttatgaag aaacggtcta tgaagataaa tctttaattg acggccaatt
    11041 gacaacggta gaactgacag cggcaggaaa actcttgcaa tacgttcaca aaacacaaat
    11101 gcgagaactc agccacttgc aagcattggt tcactatgag atcaaggatt atttgcagat
    11161 gtcgtatgcc actaagtcaa gtttagattt ggtagaaaat gctaggacta ataaaaaaca
    11221 tggaagtctc tattggctgt tagatgaaac caagacagct atggggatga ggcttttgcg
    11281 ctcatggatt gatcgacctt tggtttctaa agaagctatt ttagagcgtc aagaaattat
    11341 tcaagttttt ctgaatgctt ttattgagcg aaccgattta agcaatagtt taaaaggtgt
    11401 ttacgacatc gaacgcttat ctagtcgcgt gtcttttggc aaggcaaatc cgaaagattt
    11461 acttcaattg gggcatacct tagcccaagt gccttatatc aaagctatct tagagtcttt
    11521 tgacagtcct tgtgttgaca aacttgtcaa tgatattgac agtttgcctg agttggaata
    11581 cttgattaga acagccattg atccagatgc accagcaact attagtgaag gaagtattat
    11641 ccgcaatggt tttgatgagc gcttggacca ttatcgtaaa gtaatgcgag aggggacagg
    11701 ctggattgcg gatattgagg ccaaagagcg tcaagaaagt ggcattaata acctaaaaat
    11761 tgattacaat aaaaaagatg gttattattt tcacgttacg aattcaaatc ttagcttagt
    11821 tcccgagcat tttttcagaa aggcaacttt aaaaaattct gagcgttatg gaacagcaga
    11881 attggctaag attgaaggtc agatgttaga ggctagggaa gagtcatcta gtttagaata
    11941 cgatattttt atgtgtattc gagctcaagt tgaaacctat attaatcgtt tacagaaact
    12001 ggctaaaact ttggcaacgg tggatgtttt gcaaagttta gcagtcgttg ctgaaaccaa
    12061 tcattatatt cggccgcagt tcaatgataa tcatgtgatt acaattcaag aaggtcgtca
    12121 cgccgttgtt gaaaaggtta tgggagtgca ggaatacatt cccaatagta tctcttttga
    12181 ccaacagacc agtattcagc tgattacagg tccaaatatg agtggtaagt cgacttatat
    12241 gagacagctg gccttaacgg ttatcatggc ccagatgggt tcatttgtgg ctgctgacca
    12301 tgttgattta cctttatttg atgcgatttt tacgcgtatt ggggctgctg atgatttgat
    12361 ttctgggcaa tcaaccttta tggtggagat gatggaagca aaccaagcaa tcaaacgcgc
    12421 aagtgacaac tctcttattc tatttgatga actgggacga ggtacggcaa cttatgatgg
    12481 tatggcttta gcccaggcaa ttattgaata tatccatgat agagttggtg ctaagaccat
    12541 atttgcaacg cattatcatg aattgacaga tttgtcaact aagttgacaa gtctagtcaa
    12601 tgttcatgta gcaacgcttg aaaaagatgg cgatgttacc ttccttcata agattgctga
    12661 gggaccggcg gataaatctt acggtattca tgttgcaaaa atagcaggac tgccaaaatc
    12721 cctattaaag agagcagacg aagttctgac ccgtttagaa acacagtcac gatctactga
    12781 gataatgtca gtccctccac aagttgagtc aagcagcgct gttagacagg ggcaattatc
    12841 cctttttggt gatgatgaga aagctcatga gattaggcaa gcactggaag ctattgatgt
    12901 catgaacatg accccgtttc aagcaatgac aactctttac gaattgaaaa agttgttata
    12961 gtctttcagc tgaaaatgaa aaagatgctt tctatattga aggcatcttt ttgttctgtc
    13021 aaaaacggtc cgaggccttc ggctatttat taagtgtgtt ataatagtcc ataagaatgc
    13081 gaggaaatta tgacaaacat tattggactt ggattggcag tctttacagg aaattgacag
    13141 tccttaagca ttgatatgac tgtgtttttg aaaaaatata ggttttaagt ttccttagac
    13201 ttccctcaaa agtccacaaa aaggtgaaca aaaaaagacc tttacaggtc ctttacacaa
    13261 tgagttcagc aggcaagaac tagcgtggtt tagatactac gctttttagt ttgccttatg
    13321 gtttattata gcatgattag tgtcattgag gaaagaaact accctctcaa ccagtcttta
    13381 aagttccacc attggtcttg gaagctgtca cctacacgtt ggtaccaggt tttattcgct
    13441 tcttcttgtt gctgttgttt aaataatttt aacgcatcat cttcttggtc tcgtttctca
    13501 agttcctctt caattttttt tatttcttca tcgtactgct tatcttcttc tatagatgct
    13561 gaatctcgat aaaaggagta tccagctccc caaaaatctt catccttgaa tgtaaaagtg
    13621 actttttcac cttttttaag ttgagacgat aatttaatag tatgttgagt gttgtaaggt
    13681 aatctcttag aaaagttacc ttctttattt tctgattgat tgcttgaagg tttttgttct
    13741 ttatcggggg tttggttact ttctctggaa actttgacag accatgcttg aggaagccgg
    13801 acttttattt cagaatctcc aacggcaaag tctgagacag taacttgttt tactttttgc
    13861 tgtggtccat caaggataaa tttattttgt actaatgttg tagcactggt atccgccttc
    13921 acattcgtcg ctacgctaac cgtaagcaac gtcatagcta acattaattt ctttttcact
    13981 ttattctcct tttaagtgtt ttttataatg attagctaca caataacaat tagacgccta
    14041 aaaattccat tctatttttt gtggttttat aaaattctga cctatttaat cagctttcca
    14101 aacgttaaaa acacctttac gttaaattgt ctatgttgag acgtattccc taaccatatt
    14161 agagatatat tgatttttag ttattgttaa aggcgaatat tattttttaa cgctccacct
    14221 ctgtaattct ccgaaaactc gagcaaagct cgtttcttag tctcataata ccagctttga
    14281 cttctgttaa gttctgctat gatgtcttgc tgaggttttt tctcactgat taagtaacac
    14341 tcaatcagta tttgtctgta ttctatttta gacagttggt taatggcaaa cttgatagcg
    14401 tctagttcct ctagagcgca ttctcggctt atttcaaggt gttttctgcg cgtgggatga
    14461 tattctatat caaactggta aagctcgtta tagcttaaac caaggctatt ggcgatacgt
    14521 tgccatctat gaaactcttt tagtttacga atagcgttct tcttgctcat ctaatacctc
    14581 taaagcttct ctatgtaatt taaaaacggt attccttgaa tgacctagtt tatcgggtat
    14641 ctcatcccat gataagccat ccacgtatct agccttaata acagctatct gtctctcatc
    14701 ttggagtgtg gcgatcatgg ctagtctctt atcacgttct ttagctaaat ataagagttt
    14761 tttagctgta cctttttcga tatgtcttat tgcttcagga ttatgaaaag catttatcag
    14821 cttgatgtct ttatctcgtt gttcctcaaa taaggttatt aaagcgaaaa gtagtttcaa
    14881 ttctttaagt tgttctttag cgctcatggt cttttctcct ggttatggta taatttattt
    14941 aagcttaaat ttaaccaagg gggcgttccg tgtggacgtc tttttgtttt gttcgttttg
    15001 taaactagat attttttgta gtacttcgct tttggcttct aaaatcgttt ctaagcactt
    15061 tttagagttt atagtataaa tcatcaactt agtagctaga agcgctaaaa caatgtttta
    15121 ttttagtctt agatggttat tctttgtggc agggttatag gctaaaatga gatgtcaaat
    15181 cctttcatat caagttttta atcttcggcg aaaatttcaa aaagggaatt ttttgcacgg
    15241 aaaagggcgc gttcttaagt ttccgaacaa tatagccccg tttaaaaatg aagggggtag
    15301 tttccgaata ttatagccaa tacctgtcac ccttatccat atagtaatga aatcttctcc
    15361 agtgataaag gtatttggtt aatctcatgt actttggacg tttaggaaag tcatcacgac
    15421 tataatatcc atgaatgtgt cttgcttctg gatttacttt caaacactct ttaaaggcta
    15481 attgccagta gtagcaacag tctgtcttgc ttcgattgag tgtggcttga tgaatcttct
    15541 gacaagaacc acaagcaaag gcatgagaag ccttaaataa tttccgacaa cgtctctcac
    15601 agtcaggaca cacgaaaaag taacgtttac caccataagt tcctggaatc gtttcaagca
    15661 ataggccttg accattgtag tgaatcacta gcccatctag gtctatgcgg atagcttggt
    15721 cacctattga tcctgtaact cttgtcttcc cctgtgtctt cattgattta atgatatttt
    15781 caatagatag ttctaacatt ctttctcctt aaaactcaaa caacccaaaa ctattgataa
    15841 aacgacaaaa agagggaaaa ccctctgaat gtctatttaa cgagtaactg accttcaaca
    15901 accatatcat acaaatggtt aaaggcttga ctgatagact caaggatggc ccctaagtct
    15961 tctggcgtca tctctttata attcatagag aggtgttcag ccagttggtt ctgatcggag
    16021 atgaaagcta taagtgtggc tcgattatta actttccctt gagtactttt agataaagaa
    16081 accacgcgct gatgatcaag ttcttcatcc gtcatatcct caggttggtt gtaatagtcc
    16141 ttgaaactat cacagatacg cttgaagact ttgtttagtt ttctgtcctc ggcatatttt
    16201 aagactaact gattagcacg accaccttgg tcatcattgt gataagttgc gtcaatcact
    16261 ggttgctcat aggtcccagt catatagcct aaaatagcat ggcaggctac ttgtgcggta
    16321 tcaaagtctt taaacgtgta gtggaatgtg aatgtctttg gtgtgtctga aaatgttctc
    16381 atgctatttc tcctttgtga ttgctataat gtctgataaa ttgatgatgg cagaaggaca
    16441 tgctacccag tttggttgtt ggccagataa aagatatttg atcaactcat catagagggt
    16501 gcggtctcct tgtatggtga tggtgttgcc acctcgtgtg tgtaatttta gtttcatatc
    16561 agttacctgt acaagaccaa tagtccggtt cttgaatcca tgtcttcata attgccataa
    16621 gtggcttctt ggaatttaat gtctatcaca gataccgata gggtaaagag attgacccga
    16681 tattcaaaat catctagtga ttcattgtgt ttttgataaa atagtttgat tttcattata
    16741 taacctccga attttatacg ttttatacgt ttggtttttc aaacgtataa aatttaaagt
    16801 cagtcgtatc aagggtttaa gtctcttttt at
//
LOCUS       DAUGSW010000031        16081 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUGSW010000031 DAUGSW010000000
VERSION     DAUGSW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16081
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.031"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            64..294
                     /locus_tag="VIB18_001267"
     CDS             64..294
                     /locus_tag="VIB18_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEQ8766272.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            421..1107
                     /locus_tag="VIB18_001268"
     CDS             421..1107
                     /locus_tag="VIB18_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8766273.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            1107..1841
                     /locus_tag="VIB18_001269"
     CDS             1107..1841
                     /locus_tag="VIB18_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766274.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            1990..3399
                     /locus_tag="VIB18_001270"
     CDS             1990..3399
                     /locus_tag="VIB18_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEQ8766275.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVTTFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            3577..5271
                     /locus_tag="VIB18_001271"
     CDS             3577..5271
                     /locus_tag="VIB18_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8766276.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            5479..6333
                     /locus_tag="VIB18_001272"
     CDS             5479..6333
                     /locus_tag="VIB18_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEQ8766277.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGRFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            6486..7826
                     /locus_tag="VIB18_001273"
     CDS             6486..7826
                     /locus_tag="VIB18_001273"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEQ8766278.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRWIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            7804..8019
                     /locus_tag="VIB18_001274"
     CDS             7804..8019
                     /locus_tag="VIB18_001274"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEQ8766279.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            8019..8891
                     /locus_tag="VIB18_001275"
     CDS             8019..8891
                     /locus_tag="VIB18_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEQ8766280.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            8884..9711
                     /locus_tag="VIB18_001276"
     CDS             8884..9711
                     /locus_tag="VIB18_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEQ8766281.1"
                     /translation="MPKERVDVLAYKQGLFKTREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQEVVAKAHKEFEKHEKE"
     gene            9698..10168
                     /locus_tag="VIB18_001277"
     CDS             9698..10168
                     /locus_tag="VIB18_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8766282.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            10190..11851
                     /gene="recN"
                     /locus_tag="VIB18_001278"
     CDS             10190..11851
                     /gene="recN"
                     /locus_tag="VIB18_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEQ8766283.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLEAELKSLEKQLVAAASELSVSRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            12023..12961
                     /locus_tag="VIB18_001279"
     CDS             12023..12961
                     /locus_tag="VIB18_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8766284.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFNDDSFISQNETDKMFENLTDDR
                     LLNELDEEDEEDTIEPEQNVMMPSDDELFDLTDAVETRLTVSSASHLEAELPKPHLRS
                     LSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAHY
                     EDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVAKR
                     KIALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            13177..14028
                     /locus_tag="VIB18_001280"
     CDS             13177..14028
                     /locus_tag="VIB18_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8766285.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKVLDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            14021..14863
                     /locus_tag="VIB18_001281"
     CDS             14021..14863
                     /locus_tag="VIB18_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEQ8766286.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            14841..15428
                     /locus_tag="VIB18_001282"
     CDS             14841..15428
                     /locus_tag="VIB18_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEQ8766287.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            15527..15802
                     /locus_tag="VIB18_001283"
     CDS             15527..15802
                     /locus_tag="VIB18_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEQ8766288.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
BASE COUNT         5134 a         2631 c         3440 g         4876 t
ORIGIN      
        1 cttgttagtt tcccttgttt tgtgttaaaa taagagggat aaaaaacgaa taggagaaac
       61 gaaatggaat cacatttggt gagaatcatc aatcgtttgg agttgatggt gacagatggc
      121 ggtaatctca agcgaaattt tgaacgcgat ggtgttgttg ttgcagaagt tgccttttca
      181 aatgatcctg aaaatggacc tgttttcaca ttgcgtgatg ttgaagcgcg tgagtcatat
      241 tcctttgata gtattgactt aattgcaatg gaaatctacg atttattata ttaagcttga
      301 catagtaaag agacttgcct gaggcaggtt tttttattgt caaaaagtat tgtattaata
      361 ttcatcagat ggtataatta tctttattgt aatgaaccta ggacttatga ggagatataa
      421 atggatttgt catttttgcc caaatactgg gcctacttta actacggtgt acttgtcacc
      481 attatgattt cagtcagcgt tgtctttttt ggaaccctta ttggtgtctt ggtaaccctg
      541 attaagcgta gtcatgtgaa gccgttgacc tgggtcgtta atctttacgt ttggatcttt
      601 cggggaacac ctatggtggt tcaaatcatg attgcctttg cttggatgca ttttaacaat
      661 atgcctacta ttggttttgg ggttttagac ttagactttt caagactact tcctggaatt
      721 attatcattt cattgaatag cggtgcttat atttcagaaa ttgttagagc aggtattgag
      781 gctgtaccaa aagggcaatt agaagcagct tattcactag gtattcgtcc tcaaaatgcc
      841 atgcgttatg tgattttgcc tcaggccttt aaaaatattt tgccagcctt aggaaatgaa
      901 tttattacca ttattaagga tagtgctctt ttacaaacca ttggagtgat ggaactttgg
      961 aatggtgccc aatcagtggt aacggctact tattctccaa tttccccttt actggtggct
     1021 gctttttact acttaatggt cacaacagtg atggcacagt tattggcagt cttagaacgt
     1081 cacatggcgc aaggaggtaa tcattgatga ctgaggccat tatttcaatt aaagacttgc
     1141 acaagtatta tgggcacaat gaagtgctta agggaattga tttagacatt atgccaggag
     1201 aggttgtggt gattattggc ccgtctggtt ctggaaaatc gaccttactt cgaaccatga
     1261 atcttttgga agtaccaact aagggacaga ttaggtttga ggggattgat attaccgata
     1321 agaagaacga tattttcagc atgcgtgaaa aaatgggaat ggttttccag cagtttaacc
     1381 tctttcccaa tatgactatt ttagaaaata tcactttatc gccaatcaaa actaagggaa
     1441 tggctaaagc agaggctgac aaaacagcct tgagcttgtt ggacaaagtt ggattatcag
     1501 aaaaagccaa ggcttatcct gctagtcttt ctggtgggca acagcagcgg attgcgattg
     1561 cgcgtggact ggctatggat ccagatgttt tactctttga tgaaccaact tcagctctag
     1621 acccagaaat ggtgggtgag gtcttggctg tcatgcaaga tttggctaaa tctgggatga
     1681 ctatggttat tgtgactcat gaaatgggct ttgctaaaga agtcgcagac cgtgtgattt
     1741 ttatggatgg cggcgttatt gtggaagaag gaagtcctaa ccaacttttt gatctgacta
     1801 aagaagaacg tacaaaagat tttttgagta gagtattata aatctgttct atgaattata
     1861 aaaggaagtc ctaaatgatt taggacttcc ttttataatt tgctaaggca ttttatagga
     1921 gattactttt ctttttgtta aaataaaaaa aaatagttgc attatttgca tagaagaaag
     1981 ggatctgtta tggtttcagt gatgtggttt cgtagagatt taaggattga tgatcaaaaa
     2041 gctttagctc atgctattgc tagtcaatca ccaaccttat gtgtgtttca atttaacaag
     2101 gagcaattaa atctgctaca tagtcggaat caatctagtt ttattactag cgttttggct
     2161 tttagaaagt tattaaaatg tgaaggtatt gacttatatc taatgtatgg agacttaatg
     2221 acctgttttg aacaattatt gacacaatta aaagactgga cagatgtgta ttttaattat
     2281 gatgaatctg gatatggtcg tttacgtgat caaaaagcag cacaattttt caaaaaaaat
     2341 gggattgctg ttcataccta ccaagatcac tatttacatg gtagtcaaga gatcattaac
     2401 caatcaggtc agccttataa agtttttacg ccctactata ggatttggca aaattatccg
     2461 aaagagactc ctattaaagt agaactatcg caaggcaggt ggttaaatct tgagacacca
     2521 gatgatgttt taaggactgt tgagagcttt aaagatgaaa aatatcagga tgttacaact
     2581 tttgatgaag cgtcaaaaca actaaatcga tttattcaag accaattagc agcttatcac
     2641 gctaatcgag attttccagc gcagctaggg acgagtcggt tgtctccttt tttaagaata
     2701 ggagctattg gcattcgcac ggtatatcac gctgtgcgtc aagcaccaaa tagtctaggg
     2761 caagctactt ttttaaaaga attagcttgg agagactttt acaatatggt ctatgtggct
     2821 tatcctgatc agaaaactca gcctattcaa aaagcctttt ctcaaatcga atgggttaat
     2881 aatcctgact ggtttcagtt gtggaaagaa ggtaaaacgg gttaccctat tgtcgatgct
     2941 gcaatgcttc agctacaaaa gacaggatgg atgcataatc gtttacgaat gatagtagct
     3001 tcttttttaa ctaaagatct tttatgtgat tggcgtttag gagagcagta ttttcaacaa
     3061 caactaattg attatgatgc tgccagtaat attggaggat ggcagtgggc tgcttccact
     3121 ggaacagatg ctgttcctta ttttagaata tttaatcctg ttactcaagg taagcgcttt
     3181 gatcccaaag gcgagtttat taaagcgtat ttgcctcaac tagaacacgt tccagagaag
     3241 tatctccacg aaccgtggaa gatgccaaaa taccttcaag agagtgtgtc ctgtattatt
     3301 ggcacagact atcctcaacc aattgtcgat catgctaaac aacgtgaaca agctattgca
     3361 aagtatgagt gggcaaaaga aaaagcaaaa atagaatgac tgttctcatt ataagagttt
     3421 aaacaaaaag ttatcatgaa ttaagattat ttaatttaaa aaataagttg actttattta
     3481 gattatttga tactattcag ttgtctccct tagagaaagc gatttcttgt tttggagctg
     3541 atttttacca tttggtctta gaataggatg agtaatatga cttacaacga ggtatatcaa
     3601 gaatggttgc acaataatga tcttagtgat gatattaaag cagatttagc agccataaaa
     3661 gacaatgagg ctgagattca agatcgtttt tacaaaacac ttgaatttgg aacagcaggg
     3721 ctaagaggaa aacttggagc aggcaccaat cgcatgaata cctatatggt tggtaaggca
     3781 gcacaagctt tagctaatac tattattgat catggacctg aagcggttaa aaagggcatt
     3841 gcggttagtt atgatgttcg ctatcaatct agaacatttg cagaattaac atgctctatt
     3901 atggcagcta acggtattaa ggcgtacctt tataaaggga ttcggccaac accaatgtgt
     3961 tcgtacgcta ttcgtgcttt gggatgtatc tctggtgtta tgattacggc tagtcacaat
     4021 ccccaagctt acaatggtta taaagcttat tggcaagaag gttctcaaat tttggatgac
     4081 attgcggatc aaattgcaca acacatggct gcactaactc agtatcagga aatcaaacaa
     4141 atgccttttg aaaaggctct ggacagtgga cttgttactt atattgatga gagtattgaa
     4201 gaagcatata aaaaagaagt gcttggttta acgattaatg atactgacat tgataagtca
     4261 gtccgagtag tctatacccc tttaaatggt gttgggaatc taccagtgcg tgaggtttta
     4321 agacgccgcg gttttgaaaa tgtttatgtg gtacctgagc aggaaatgcc cgatcctgat
     4381 tttacaacag ttggctatcc taatcccgaa gtccctaaaa cttttgcata ttcagaaaaa
     4441 ttaggtaagg cagttgatgc tgatattttg attgcaactg atccagattg tgaccgtgtg
     4501 gctttagaag ttaaaaatgc agtcggtgac tatgtttttc tcaatggcaa taaaatcgga
     4561 gcgcttttat cttactatat cttttcgcaa cgatttgact taggcaattt accggctaat
     4621 cctgttttag tgaaatccat tgtaacagga gacttgtcac gggctattgc tagccattat
     4681 ggtattgaaa ccgttgaaac attgactggt tttaagaata tttgtggcaa ggcaaacgaa
     4741 tatgatgtga cgaaacagaa aaactacctg tttggttatg aagaaagtat tggtttttgc
     4801 tatggcactt ttgttcgtga caaagacgct gttagcgcct ctatgatgat tgtagaaatg
     4861 gcagcttact acaagaaaaa ggggcagaat ttactagatg ttttgcagac tatttatgcg
     4921 acatttgggt attataatga acgtcaaatt gccttggagc ttgaggggat agaaggacaa
     4981 aaacgcattg cgaggataat ggaagatttc agacagacac caatagctag tgttgcagag
     5041 atggcgttag acaagacaat tgattttatt gatggctatc aagattttcc aaagcaaaac
     5101 tgtctcaaat tttatttgga tgatggttct tggtatgcac ttagaccatc aggaacagag
     5161 cctaaaataa aattttattt atatactatt ggccaaacac aagaaaatag tgcaacaaaa
     5221 ttagatgcta ttgaagcagc gtgtcgcaca aaaataaatc aggttaatta aacatcaaaa
     5281 atggataaca cttttacact atttttccat ataaacaact acaaaaggag gtgagacttt
     5341 taggcacctt ctttttcttg taggtgccac taatcaattt aatcgactca aaccaatact
     5401 aaaaaataag taagagtata aagaacaggc atctattttt ttgttataat agaaaaatga
     5461 aattaaaggg agatgtcaat gacagaacta attgatggta aagccttagc tcaaaagatg
     5521 caacaagagt tagcagctaa agtcaacaat ctaaaacaaa aaaaaggaat tgtaccaggc
     5581 ttagccgtta ttcttgtagg tgatgatcct gctagtcagg tgtatgtccg taataaagag
     5641 cgtgcagctc ttactgtagg ttttaaaagt gagaccgtta gattatcaga attcatttgt
     5701 caagaagagc ttattgcagt aatcgaacgt tacaacgcag ataacactat tcatggtatt
     5761 ttagtgcagt tacccctgcc aaatcatatt aatgataaaa aaattatcct cgccattgat
     5821 cccaaaaaag atgtggatgg ttttcacccg atgaatacag gtcacctttg gtcaggacgt
     5881 cccttgatgg ttccttgtac tccatcaggg attatggaat tgcttcgaga atataatgtt
     5941 aaccttgaag gtaaacatgc cgtcattatt ggcagatcga atatcgttgg aaaaccaatg
     6001 gcacagctct tactggacaa aaatgcaaca gtcacgttga cacattcaag aacacgtcaa
     6061 ttagaagaag tatgtcgctg tgcagatgtg ttgattgtgg caatcggaca aggtcgtttc
     6121 ataacaaaac aatatataaa agatggtgcg atagtgattg atgtgggaat gaaccgtgat
     6181 gataatggca agctaattgg agatgtggcc tttgatgagg tggcagaagt tgcagcgaaa
     6241 atcacccctg taccaggagg tgtcggtcct atgacgattg ctatgttgct agagcaaact
     6301 tatcaatctg ccctccgtag tactcataaa tagttataat tagacaattc aacataagag
     6361 aatataagaa gtcagcaatg gcttcctttt ttgtttttct gctcactatt tattcagaaa
     6421 aatggtataa ttgcattagt atgcaaaggg actatgtcag gtccaactaa gtgaaaggtg
     6481 gcttgatggc agattattta accgtcactc atttgacgaa atatttaaaa ttaaaatttg
     6541 accgtgaccc ttatttggaa cgggtttatc tgactggtca agtgtccaat tttcgaaaac
     6601 gaccaactca tcaatatttt tccttaaaag atgaaagtgc tgtgattcaa gccaccatgt
     6661 gggcaggagt ctataaaaaa ctaggattcg acctagaaga aggcatgaaa attaatgtaa
     6721 ttgggcgagt ccaactttat gaacctagtg gctcttactc tatcgtgatt gaaaaggcag
     6781 agccagatgg tataggtgcc ttggctttgc agtttgaaca attaaagaaa aaattaacgg
     6841 cagaaggtta ttttgagcaa aaacacaagc agcccttgcc acagtttgta tcaaaaattg
     6901 gggtcattac aagtcctagt ggtgctgtga ttcgagatat tatcacaacc gtttcacggc
     6961 gttttccagg ggttgagatt ttattattcc caactaaagt acaaggtgat ggagccgccc
     7021 aagaagtagt ggctaatatt cgaagagcca atcaaagaga ggatttggat ttgctcattg
     7081 tcggccgtgg aggtggctcg atagaagacc tttgggcctt caacgaggaa atagtggttc
     7141 aggctatctt tgaatcgcaa cttccagtga tttcgagtgt gggtcatgaa acagacacga
     7201 ctttagcgga ttttgtggca gatcgcagag cagccacacc aacagcagca gcagagttag
     7261 caacgcctat tacaaaaaca gatcttatgt cttggatagt agagcggcaa aatcgttcct
     7321 atcaggcctg cttgaggtgg attaagcaac ggcaagagtg ggtggataaa ctctcgcaat
     7381 ctgttatttt taggcaacca gaacgattat atgatgccta cctgcaaaaa attgatcgcc
     7441 ttagcatgac cctgatgaat acgatgaaag atcgtctgag ttccgccaaa gaaaacaagg
     7501 ttcagttgga ccatgccttg gccaatagtc aattacagac aaaaatcgag cgataccaag
     7561 accgtgttgc taccgctaag cgtttactga tggctaatat ggctagtcaa tatgatagtc
     7621 agctggctcg ctttgaaaaa gcacaggatg ctttgttatc actggatgcc agccgaatta
     7681 tcgcccgtgg ttatgcaatg attgaaaaaa atcaagcact ggtagcctct gtaagtcaga
     7741 taacaaaggg tgatcagtta accattaaga tgcgtgatgg acaattagat gtagaggtaa
     7801 aagatgtcaa aaacgaaaac atttgaagaa aatttacaag atttagagac tattgtgaac
     7861 aaacttgaaa atggggatgt ccctttggaa gaagctattt cagaatttca aaaaggaatg
     7921 cttctctcaa aagaacttca aaagacctta caagcggcag aaaaaacact cgtcaaagtg
     7981 atgcaagctg atggcacaga agtagatatg gatgattaat ggacaaatta gctagaattg
     8041 acgaagccat tcgtcgctac tataagacga ctagtaacgg tgtatctgaa gagttgattg
     8101 atgctatctt gtattctgtt gacagtggtg gcaagcgcat tcgaccactt atcttattag
     8161 agatgattga gggatttggg gtatcgttac agaatgctca ttttgatttg gctgcagccc
     8221 ttgaaatgat tcatacagga agtctgattc acgatgattt gccagccatg gataatgatg
     8281 attaccgacg tggtagactg accaatcaca aacaatttgg agaagccacg gccattttgg
     8341 cgggagatag cttattttta gacccctttg ggttaatagc tcaagctgaa ttaaatagcg
     8401 aggttaaagt agccttaatc caagaacttt ccctagcttc aggaactttt ggcatggttg
     8461 gtggtcagat gctagatatg aaaggggaaa atcaagcttt gagtctccct cagttgtcac
     8521 tgattcacct caataaaacc ggaaaattat taacttttcc ttttaaagca gcagctcttg
     8581 taacagaaca ggctattact gttcgtcaac aactagagca ggcgggaatg ctcatcgggc
     8641 acgcctttca gattagggat gatattttag acgtgacagc tagctttgaa gatcttggaa
     8701 aaacgcctaa aaaggattta tttgcagaaa aagctactta cccaagttta ttggggttag
     8761 aagcctccta ccaactgttg acagagagtt tagatcaggc tttgacgatt tttcagacac
     8821 tcgaaagcga tgtaggcttt aagcctcaaa taattacaaa actgatagaa gggttacgac
     8881 ttaatgccta aagaaagagt agatgtgtta gcctataagc aaggattatt taagaccaga
     8941 gagcaagcta agcgtggtgt catggcaggc ttagtggtct ctgtgattaa tggccaacgc
     9001 tatgacaagc caggtgacaa aattgacgat gggactgagt taaaacttaa aggtgaaaaa
     9061 ctcaaatacg tcagtcgtgg tggattaaaa ctggaaaagg ggctgcacgt ttttggtgta
     9121 tcagttgcta atcaaattgg gattgatatt ggcgcttcaa caggtggttt taccgatgtt
     9181 atgttacaag atggggccaa actagtctat gccgtcgacg ttgggactaa ccagttggta
     9241 tggaaactca gacaagatcc acgagtaaga agtatggaac agtataactt tcgttatgct
     9301 cagccagaag actttaatga gggacagcct gtatttgcca gtattgatgt gtcctttatt
     9361 tctctcagct tgattttgcc agccctgcat aacgttttgt cagatcaggg acaggttatt
     9421 gctctcatta aaccgcaatt tgaagctggg cgcgagcaga ttggtaaaaa aggcatcgtc
     9481 aaggacaaac agattcatga aaaagtgatt caaaaggtca tggattttgc ctcaggttac
     9541 ggatttacag ttaagggact tgatttttcc cctattcagg gtggtcatgg caatatcgaa
     9601 tttttagctc atcttgctaa gtcacagaca cctgaaacgt tagccccgca tttgattcag
     9661 gaagttgttg ccaaggcaca taaggagttt gagaaacatg aaaaagagtg aacgacttga
     9721 attaatcaaa aaaatggttt tgacgcatcc aattgagacg caacatgacc tcttaagatt
     9781 attggcagag catgggttag aattaaccca ggctactatt tcaagagaca tgaatgaaat
     9841 tggtatagta aagattcctt ctggcagtgg acgttacatc tatggtcttt ctcaagatag
     9901 tggaaaaaag atcgttcaag gacctagatc gataaagagc actattttag ctgtatctga
     9961 caaaacaaaa ggtttagaac aacacctcta tttaaaagtc gtacctggca atagtaaatt
    10021 aatcaaacgt tatttattag cagatttttc aaaagctatt tttagtctta ttgctgatga
    10081 tgatagttta ttgttaattg caaagtctcc ttcagaagca gatatgatac gccaagaaat
    10141 tttgctttgg atgcagggta taacctagaa aaaaataggg gagaaagtga tgttattaga
    10201 aatttctatt aaaaattttg ctattattga tgaaatttcc ctaaattttg aaaatggtat
    10261 gacggttttg acgggtgaaa ctggagcagg aaagtctatt attattgatg ctatgaatat
    10321 gatgcttggt gcgcgtgcta gtacagaagt gattcgtcgt ggagctaata aagcagaaat
    10381 tgaggggttc ttttcggtag atgctacccc agaactggtt gcgtgtctgg aatcatcagg
    10441 tattgctatg gaagaagaac ttattattcg ccgagatatc tttgccaatg gcagaagcgt
    10501 gagccgcatt aatggtcaga tggttaacct agccacctta aaacaggtcg gacagttttt
    10561 ggtagatatt catgggcaac atgaccaaga agaattaatg cgaccacagc tccaccagca
    10621 aattttggac gcttttggtg ataaggcttt tgagcaattg aaagagaact atcagcttat
    10681 ttttgatcgt tataaaagct tgcgtcgcca ggttattgac aaacaaaaaa atgaaaagga
    10741 acacaaagat cgtattgata tgttggcctt tcagatagca gaaattgaag ctgctgcctt
    10801 gagtcgaggt gaggacgacc ggttaaatca agaacgtgat cgcttaatga accacaaaca
    10861 aattgctgat accctgacca atgcctacgt catgctagat aatgacgatt tttcaagtct
    10921 atccaatatt cgctctagca tgaatgactt actatcaatt gagcagtttg attcagagta
    10981 caaagggatg tcgacttcga tttctgaagc ctattatatt cttgaagaag tgagcaagca
    11041 attatcagat accattgacc aactggattt tgatggtggg cgattacagg aaattgaatt
    11101 tcgcttggat acactcaata gcttaacccg taaatacggt ggtaatgtga atgatgtgct
    11161 tgactactac gataatatta tcaaagaata ccagctatta acaggagatg acttgtcttc
    11221 aggggatcta gaggcagaat tgaaaagctt ggaaaaacaa ttggttgctg ctgcttcgga
    11281 gttaagtgtc tctcgccatc aattggcgga gcaattagaa gctgagatta aagctgaact
    11341 taaggaactt tatatggaaa aagcagattt caaagttcac tttaccacat caaaattcaa
    11401 tcgtgatggt aatgaaagct tggaatttta catctctact aatccaggcg aaggattcaa
    11461 gccccttgtc aaggtggctt ctggaggaga gttatcacgc cttatgttag ccatcaaggc
    11521 tgctatttct agaaaagaag ataagacgag tattgttttt gatgaagtag atacaggtgt
    11581 ttctggtcgc gttgcgcaag ccattgccca aaaaatttat aaaattgggc gacatgggca
    11641 agttctcgct atttcacact tacctcaagt tattgctatt gctgattatc agtattttat
    11701 ttctaaagaa agtaaagaag agtccaccgt ttctaaggta aggttattaa ctcctgaaga
    11761 acgtgtggaa gaaattgcta gcatgattgc aggaacagat atgacacaag ctgctcttac
    11821 gcaggctcgt gaactacttg ccaaacatta agattatgtt tggtatttga tattttcata
    11881 attagatgaa attgattttt taggtgctaa aataatcatt gtgctagacc atttttcctc
    11941 tgttaatctg gcttggtttg ccttgacaaa cctctgagaa atagtagaat agataagaga
    12001 attttaagct gaggggatag aaatgactag taaaaaagcg tgtttatcaa gcatcattgt
    12061 gttagcaagt ttaacgtgtg gaaatgatac tgttagtgcc aatcatctct cagcaactgg
    12121 agataagttt gatgattgct caacacttgt tgaaaaagat gtggccccta aagatgaact
    12181 tgagatgtta gcatggtcct cgtctcaaac aactgatgat gctgacagag actatgaaga
    12241 ttttctcgat gatgattctt ttaatgatga ttcttttatt tctcaaaatg aaactgataa
    12301 gatgtttgag aatttaactg atgataggtt attaaatgaa ttagatgaag aagatgaaga
    12361 agatacaatt gagccagagc aaaatgtaat gatgcctagt gacgatgagc tatttgattt
    12421 aactgatgct gttgagacac gccttactgt ttctagtgct tcccatttag aggctgaatt
    12481 gccgaaacca catttgagga gcctatcaga tacagcactg cggtctggtg aaattagagg
    12541 acatttagat aacaaactgg acgctttgtc tgtaacagct acaaagttag cattaacgat
    12601 ggctcaaaaa tttgatttga caacgcatgt ctattctata ggtgaaagct ttagtgaagt
    12661 attagctgct cattatgaag atagaaaagc agaatcagct ttttctaaga aaaagagatt
    12721 tcaccttcct attgctactc cagatgttgt tatagaggag ttaaggcgcc tagtctcttc
    12781 tattggaagt tcaaaagaag atgtttcagt tccttataat cggaagctag gtatggcagt
    12841 tgcaaaaaga aaaatagccc tgccacaaac gggagaggag ttctcttatt atccagcttt
    12901 acttggttta atgatattag gattaacgcc gattatgata ccaaagaaga taaataatta
    12961 ggtaataagt tattgtagtt gtaaaaaacg gggcaaatgt tcaagcgtga aaaggttgac
    13021 ttttgcctcg ttttgtatct cgttattgct aaggcatttt cttcgagcag ctagtgctcg
    13081 ccatacctat ctaccgagtg attattcaat agcactacca gttttgcttt atttagcaag
    13141 gagtgttaga ataaagaggt gagaaactag tttagaatgg aaaaatacat gggaactata
    13201 aaaattgtta cagattcatc aataactatt gaaccagaat taattaaagt tttagatatt
    13261 actgtagtac ctttatctgt catgattgat agcaaattat attctgataa tgatttaaaa
    13321 gaagaaggtc attttttgag ccttatgaag gctagcaaat cccttcccaa aaccagtcag
    13381 ccaccggttg gactctttgc tgaaacttac gaaaatttgg tcaaaaaagg agtaactgac
    13441 attgttgcta ttcacctctc accagcttta tcaggtacta ttgaagcttc ccgtcagggg
    13501 gctgaaatcg ctgaggcacc tgttacagtt ttagattcag gatttactga tcaagccatg
    13561 aaatttcagg tcgttgaggc agcaaagatg gcaaaagcgg gtgcaagttt gaatgagatt
    13621 ttggctgctg ttcaagctat caaatcaaaa acagagctct acattggtgt atctacctta
    13681 gaaaatttag taaaaggagg tcgtattggt cgtgtgacgg gtgttttgag ctcgctactt
    13741 aatgtcaaag ttgttatggc acttaaaaat gatgagttaa aaacgcttgt caaaggtcga
    13801 ggtaataaaa catttacgaa atggttagat agttacctcg ctaaaaatag tcatcgcccg
    13861 attgcagaga tagctatttc ttatgctggt gaagctagcc tggcattaac cttaaaagaa
    13921 agaatcgcag cttattacaa ccactctatt tcggttttag aaacaggctc tatcatccaa
    13981 acacatacag gagaaggagc ttttgcggtt atggttcgtt atgaataatc gtcatttatt
    14041 tagtgggata tttttctttg ttattagttt atgtctggcc tttttattgc taaatattat
    14101 tatccctaag tcaaattcac gtttgaaaaa gagtgatttt ctgaaaaaag aacaagtagc
    14161 tatccaatat gttgctatag gagactcatt gacagaagga gtaggtgatc taactcatca
    14221 aggtggtttt gttcctttgt taacgaatga tctcagtgaa tattttaagg ctaatgttaa
    14281 tcatcaaaat tacggcgtat ctggtgatac cagtcaacaa attcttgata ggatgataaa
    14341 acaaaagcag atacagttat ctttaaaaaa agcagatata atgacgttaa ccgttggtgg
    14401 taatgatgtt atggcagtta ttcggaagaa tttagcggat ttgcaagttt ctagttttag
    14461 aaagccagct cgtcagtatc aaaaacgatt aagacagatt atcgagttag ccagaaaaga
    14521 taataaagat cttcctattt ttattttagg catctataat ccgttttatt tgaattttcc
    14581 agaactaact gatatgcaaa aagtgattga tgactggaat accaaaacta aggaggttgt
    14641 tggagaatac gatcgtgtgt actttgtgcc aataaatgac ctcttgtata aagggataaa
    14701 tggacaagaa ggaattgtcc attcttcagg agatcaaact acaattgtca atgatgcctt
    14761 gtttactggg gaccattttc acccaaataa tactggctat caaatcatgt caaatgcagt
    14821 aatggagaaa ataaaaaagc atgaaaaaaa aatcaaacct taattggtgg aagtggagct
    14881 tcttatgtct gcttgctttt aataccgcct ttttgatggt tattgcaagt cgtctcattc
    14941 aagtaagaga acctgagtca gaactgattg ctaaaaaacc agttaaaaat atcaaaattg
    15001 gtacatttgt cacaaccaga gaacagctta acgaaactgt agcaagttat cttaaagatt
    15061 atcagactaa aaaaatgtct tataaatttt atgcgacatc ttcttctatt ttgtttgaag
    15121 gaacttatca attattaggg tatgaagtcc ctttatatat ctattttcaa cctcatcgtc
    15181 tagaaaatgg agctgtccaa ctacaggtga tctctttttc agtgggaact ctgccactcc
    15241 cagaaaaaga tgttttgcag tatttgaaat caagctacaa attgccaagc tttgttaaag
    15301 tgatgccaaa tcaatcagct atcgttgtta atttacaaga tatccaaaat gatgctaagg
    15361 tttatttaaa ggccaagaaa attgatttat ttaatgatga aatcagtttt aacatctata
    15421 agaaataagc tcaaataacg ttaaatactt gacctaatcg ctttttttag atatgataat
    15481 atctgttaaa gcattaagct tactaattat ttggaggatt tgttaaatgg ctaacaaaca
    15541 agatttaatc gcaaaggttg cagaagcaac tgaattgact aaaaaagatt cagcagcagc
    15601 agttgatgcc gtgttttcta caatcgaagc tttccttgct gaaggtgaaa aagtacaatt
    15661 gatcggtttt ggtaacttcg aagtacgcga acgtgcagct cgtaaaggtc gtaacccaca
    15721 aactggtgca gaaattgaaa ttgcagcttc aaaagttcca gccttcaaag ctggtaaagc
    15781 tcttaaagac gctgttaaat aattcgtcta gaaaaatctt gttgctatcg atgtttattg
    15841 atagcgacaa ggttcttttt ttatatttgg ggcataaagt tagtagtttt ctcttcagtt
    15901 aagccaagtt ctaaagcatg cactctataa tggtcagtca tccttctatt agtatatcat
    15961 ttccgcaggt agggggagtt tttttcatat ttgcaaatag ttgaagttag gatttttgaa
    16021 agcaaaaggt aagtttaaaa aagtttattt agaatgtttc taaattactt gacttattta
    16081 t
//
LOCUS       DAUGSW010000032        15412 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUGSW010000032 DAUGSW010000000
VERSION     DAUGSW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15412
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.032"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            147..395
                     /locus_tag="VIB18_001284"
     CDS             147..395
                     /locus_tag="VIB18_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8766289.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            432..1043
                     /gene="amaP"
                     /locus_tag="VIB18_001285"
     CDS             432..1043
                     /gene="amaP"
                     /locus_tag="VIB18_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEQ8766290.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1054..1242
                     /locus_tag="VIB18_001286"
     CDS             1054..1242
                     /locus_tag="VIB18_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEQ8766291.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1255..1794
                     /locus_tag="VIB18_001287"
     CDS             1255..1794
                     /locus_tag="VIB18_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8766292.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1835..2035
                     /locus_tag="VIB18_001288"
     CDS             1835..2035
                     /locus_tag="VIB18_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8766293.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2046..2534
                     /locus_tag="VIB18_001289"
     CDS             2046..2534
                     /locus_tag="VIB18_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8766294.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2697..3338
                     /locus_tag="VIB18_001290"
     CDS             2697..3338
                     /locus_tag="VIB18_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8766295.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3481..4023)
                     /locus_tag="VIB18_001291"
     CDS             complement(3481..4023)
                     /locus_tag="VIB18_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8766296.1"
                     /translation="MTKRHTETKACVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4141..4842
                     /locus_tag="VIB18_001292"
     CDS             4141..4842
                     /locus_tag="VIB18_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766297.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4857..7493
                     /locus_tag="VIB18_001293"
     CDS             4857..7493
                     /locus_tag="VIB18_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8766298.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLTSHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELVVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSTTSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQFYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNANHIKSVQ
                     LVVTSLNQVMTLLVFLSILLVIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7585..8181
                     /locus_tag="VIB18_001294"
     CDS             7585..8181
                     /locus_tag="VIB18_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8766299.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8192..9148
                     /locus_tag="VIB18_001295"
     CDS             8192..9148
                     /locus_tag="VIB18_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8766300.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9245..10585
                     /locus_tag="VIB18_001296"
     CDS             9245..10585
                     /locus_tag="VIB18_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEQ8766301.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELKKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKVANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10701..11585
                     /gene="truB"
                     /locus_tag="VIB18_001297"
     CDS             10701..11585
                     /gene="truB"
                     /locus_tag="VIB18_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEQ8766302.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRCLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11614..12546
                     /locus_tag="VIB18_001298"
     CDS             11614..12546
                     /locus_tag="VIB18_001298"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEQ8766303.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLTRNFEGQVYTIKEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12589..12993
                     /locus_tag="VIB18_001299"
     CDS             12589..12993
                     /locus_tag="VIB18_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEQ8766304.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            12995..13273
                     /locus_tag="VIB18_001300"
     CDS             12995..13273
                     /locus_tag="VIB18_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEQ8766305.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13263..14051
                     /locus_tag="VIB18_001301"
     CDS             13263..14051
                     /locus_tag="VIB18_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEQ8766306.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPDYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            14054..15364
                     /locus_tag="VIB18_001302"
     CDS             14054..15364
                     /locus_tag="VIB18_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEQ8766307.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDDTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALVMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
BASE COUNT         4971 a         2534 c         3192 g         4715 t
ORIGIN      
        1 aaacaaaaaa taaactaaca ctttattatt tagtttatat agtcactttt tgaaagtcga
       61 ctattaaaag actattgctt gaagaataac agctgttatt cttccttgga caaaaggtac
      121 aggagtatct aaaaaggaga attatcatgg gacttatttg gactttaatc gtcggtgcgc
      181 ttattggtgt gattgctgga gcacttacta aaaaaggcgg ttcaatgggc tggattgcaa
      241 acatcgctgc tggtctagtt ggttcttccg ttggtcaagc tttacttggt tcatggggcc
      301 cttctttagc aggaatgtct ttgatcccgt cagttattgg tgccgttatc gttgttatga
      361 tcacttcttt tgtactaaac aaaactaaca actagtttcc tctttattta gtaagtactt
      421 acaaatagag aatgttaagt agaaaagagg tctgtatgtc aaaattgtta aagattagtt
      481 attgtcttgt cggacttgtt ctattgtctg tttttggatg ggtagttgga ataaccggag
      541 gctatatata tttaccttat agttatcgtt ggctaagttg gggtatggat agttttccca
      601 atctcttaga ttcagcttta tcctattatt acttctggac agcccttgta ttatttgtta
      661 taacatttct tgctttatta gttattattt tatacccaag aatttatact gaggtccagt
      721 tacgccataa aaataaaaaa ggaacacttt tattaaaaaa atcggctatt gaaagttatg
      781 ttgcgaccgc tattcaaact gcaggtttga tgccaaaccc aacagtcaca gctaaattat
      841 ataagcggaa gtttaagatt atcgttaaag gacgtttagc ttctcgtgta gcagtggcag
      901 atcaaattag tggcgtgaaa gaagggatcg aaaaaggttt aaccgagttc ttcggtatta
      961 attatcctgt taatttcaaa gtttatgtta aagatattgc tgattctgat cgtaaacata
     1021 ttaccagaaa tcgtgtagaa taggagatct atcatggaat tttatgaaaa attcaagtac
     1081 cctattattg gtggcttggt ggggctaatt attgccatat tgctcatggc ttttggttta
     1141 ttcaaaacgc tactagcaat tattttcatt attttaggaa tatatggcgg cctgtatgcc
     1201 aaaaaaacag gtattattga tcaatttctt aatcgcaaat aaaggagact tattatgact
     1261 gaaacttata ttaaaaacac atctaaagac ttaacttcag caattcgtgg tcaattaaca
     1321 tatgatgata aagtaattga aaaaattgtt ggtttagcac ttgaaaatgt cgatgggtta
     1381 ctgggtgtaa atggtggttt ttttgctaac ctaaaagata aattagtaaa caccgaatct
     1441 gtacgtgatg gcgtgaacgt ggaagttgga aaaaaacaag ttgccgttga tcttgatatt
     1501 gtcgctgaat atcaaaagca tgtgccgact atttatgact ctattaaatc gatcgttgaa
     1561 gaagaagtga agagaatgac cgatctggat gtgattgaag ttaatgttaa agtagtcgac
     1621 attaaaacaa aagaacaatt tgaagctgaa aaagtaagtt tacaagacaa agtttcagac
     1681 atggcacgtt caacatctga atttacgagt catcaagttg agaatgttaa agcttcagtg
     1741 gataacggtg ttgaaaaact tcaagatcaa aaagctgagc cacgtgtaaa ataattatat
     1801 gtcgtcaatt aggtaagcta aaggagggtt tattgtgtca gatgaaaaat ataatgcgaa
     1861 attagatcaa gctggtggca agttaaaaga aggatttggt aagatttctg gagataaatc
     1921 tttagaaact gaaggtaaag tagataaagt tactggaaaa gttaaagagg ttattgcaga
     1981 cgccaaagat actgtaaaag gattagctaa aggcttagat aataaagata aataaagggg
     2041 acatgatgga aaaaactcaa attaaaagca ctcttactta tgacgataag gtcatcgaaa
     2101 aaattgtcgg tcatgctttg gaaaacgttg gcggattact agctgtaaca ggtggatttt
     2161 tctcaaatat taaaaataat ttggtgaatt ctgagtctgt aactgatggt gtttcagttg
     2221 aagttggtag caaggaagta gcagttgatt tagcaatcat tgtagaatac ggtaaagata
     2281 ttcctgctat tgcagaatct attaaagcta ttgtttctca aaacgttgac agtatgacac
     2341 atttgaaagt tgttgaagtc aatgtgaacg ttgttgatat tcgtactaag gaagaacatg
     2401 aagctgctag cgttactgtt caagatcgtg tcactagtgc agcttcaagt acttcacaat
     2461 ttgtatcaga acaaacagaa aaattaaaag atactatctc tgatactgta aatagtgatg
     2521 aggcagctaa ataagcaatc gtctaggaag tattattgac tagtggtgat aagtttgagc
     2581 tggtatttac cagctctttt tgtcacggtt aaaaagatac ggactattgt catctctcta
     2641 aaaatatgat ttaattagat ataaattttt caaattgtta gaaaggagta aattaagtga
     2701 taagtcctaa aaaagagata acaagttcaa aatatcaaaa aattgctatt tcagtagctc
     2761 agcgtatcgc aaatggcgaa tatgaagtgg gcgaaaagtt aaagtcaaga actactatcg
     2821 cctcgacatt taatgtatca cccgaaacgg ctcgtaaagg cctgaatatt ttagctgact
     2881 tgaaaatttt gactttaaaa catggtagtg gagctattgt gctgtcaaaa gaaagagcta
     2941 ttgagtttat aaatcaatac gaatcaaccc attccatcgc tgttttaaaa gaaaaaatac
     3001 gtgagactat taatgatcag ggaaaagcaa tggaaaaaat ggctgttttg gtcaatgatt
     3061 ttttaatgca aagtcaatct gttagtaagc aatacccatt agcaccttat gagattattt
     3121 gtagtcaaga ttcggaacat tttggcaaat ctattggtgt gttaaatatc tggcaccaga
     3181 caggagcaac tatcgtcgct attgaacatg ctggtcagtt tatcgtttca ccaggtcctt
     3241 attctgttat tgaaaaaggc gatcatattt atttcgttgg tgatgagtca gtcatttcac
     3301 gaatgaagac cttttttaat ttacgaaaag gattataagt ttgagggccc acctcaaact
     3361 ttttttgttg ctgttgagca ttattaaaag aggcagatca tcatggtttg tctttccaaa
     3421 atatctgttt agacagttgt tttggattgg gagcatgatt tcagactctt ttgatgtttt
     3481 ttaattgtct agagtaactg ctttgagaat aatatcggca acctcttcag tggtttcttg
     3541 atagccatta gcaatccaat agctgataat gctctcaata ctggcaaggt aaacttctaa
     3601 agcataggga taaggaatat ggtattgatt ggtcacaatg tcttggaaac cagtaatagt
     3661 agtcaaaaat tggtaacaga aatccttgat gagttgcgga aatttgaggt aagaaatagt
     3721 agcgagtgcg gttataaatt ctctatgttc tataaggtag gacaaggttt gattgaggac
     3781 ttgtcgagtg tctgtgtaga tttcagcctg atttaacaaa cggtacaaat catccagagt
     3841 gtcatttttg aaatgattca tcatgtcaaa tttatcagtg tagtggaggt agaaggttcc
     3901 tctattgata ccagcctttt tagtaaggtc agagacagta agagtttcaa aagattgttc
     3961 agttagtaag gtggttaagg cggtctttac acaagctttg gtttcagtat gtcttttggt
     4021 cattctcagg tgctccttaa atcaacagtt gcgtcagatt tgttcttgtt aaatacttat
     4081 ggccattata taataaggct ataattaaat caacactatg ttcaaataat ggaggggcag
     4141 atggctttta ttgaattaaa acaggtttca aaatcttatc aggtaggaga gacgactgtt
     4201 tttgccaacc acgaagtgtc ttttgagatt aataaaggag aactagtggt tattttggga
     4261 gcatccggag ctggtaaatc gacagtcctc aatattttgg ggggcatgga cacagtagat
     4321 gcaggtcaag taattattga tggcaaagac attgctcatt acacgtctaa ggccttaact
     4381 cagtatcgtc ggaatgctat tggtttcgtt tttcaatttt ataatttggt tcctaatttg
     4441 acagctaaag aaaatgttga attagcagtt gaaattgtag cagatgcttt agatcctgtg
     4501 accattttaa aggaagtagg actcagtcat cgtctggatc attttcctgc tcagctctca
     4561 ggtggtgaac agcaacgggt ttcgatagca cgtgccttag ctaaaaaccc taaattgctt
     4621 ctttgtgatg aacctacagg tgcccttgac taccaaacag gaaagcaaat tctaaccctc
     4681 ttacaggata tggcacgaac taaggggacc acggtagtta ttgtaaccca caatgctgct
     4741 attgctccga tagctgatcg tgtcattttt atgcatgatg cacaggttac caagacagtc
     4801 attaataagg aacctgcaag cattgagaca attgattatt aagaggaagg tgtcgtatga
     4861 taaagaaaac cttatggaag gatattttga gagctatcaa gaatagtaaa gggcgattca
     4921 tttccttatt tttcctaatg gccttaggct cctttgcttt agttggactt aaagtcaccg
     4981 gtccagatat ggaacgaaca gccagccgtt acctcgaaag acaccaggtg atggacctaa
     5041 cggtactgac ttctcatcaa ttttcccaag ccgataaaca agagttagat acgttaaaag
     5101 gggctcattt agaatatggt catttacttg atgtcagtct aactagcaac cagaaatctc
     5161 ttaggctcta tagcgtgcca aagaaagtgt ctaagccagt cttggttaaa gggagttggc
     5221 caaagcgaga gacagatttg gttttatcct cctcacttgc taaaaactat cagattggag
     5281 atgaactagt agtcacctca cctatggaag gtttgctgac gacaacccat tttcaagtgg
     5341 ttggttttgc gaattcttca gaagtttggt ccaagtccaa tttaggaagt tcctcaaccg
     5401 gagatggaag tctctacgct tatgcttttg ttaatccaaa cgtttttaaa agtgccttta
     5461 acctgctgcg catccgtttt agtaatcttc gtctgacaaa cgctttttcc aaagactatc
     5521 aaaaaagggt aacccaaaac caagctcatt tggataatct acttaaagat aatggccaga
     5581 agcgttatga tgacctccaa aatcagtatg accttgcctt aaaaaatggc agagcagcac
     5641 ttgcaaagga aacagtgaaa ctagctgcga gtgaggagaa cttaactttt ttagaaggct
     5701 ctgctttaca agaagctaag catcagattg aacaaggcaa acaagcatta gccaaggagg
     5761 aaaagcagtt agagcaggtg caggctacaa aagataagct agaaaaaccc agttacctga
     5821 cttataatcg ctcgacccta ccaggaggag aaggatatca tacttatgca acttcaacga
     5881 cctccatttc aaatgttgga aatatttttc ctgttgttct ttatctcgta gctgctctag
     5941 tagcctttac caccatgaca cgttatgttg atgaagaaag aacaagctct ggtctattaa
     6001 aagccattgg ttattctaac aaggatatca gtttaaagtt tcttatctat gggcttttag
     6061 ccagtttttt agggacaact ttaggtatta ttgggggaac ttacctctta tctgccttga
     6121 tttcagagat cttaacagga gctttgacta ttggaaagac tcacctttat agttattggt
     6181 tttataatgg gatagcttac ttgctggcta tgttatctgc tgttttacca gcctacttaa
     6241 ttgtcaaaaa ggaattattc ctcaatgcag ctcagttatt gctgcccaaa cctcctagta
     6301 agggggcaaa aatctggttg gaacacctta cttttgtctg gaaagctctg tcctttactc
     6361 acaaggtgac catacgtaat atttttcgct ataaacaaag aatgctgatg accattgtag
     6421 gcgttgcagg ctctgtagcc cttttatttg caggcttagg gattcagtcg tcattagcca
     6481 aagtagttga gcatcaattt ggtgatttaa cgacttatga tattttggct gtcggttcgg
     6541 ccaaagcgac agcgacagag caaactgact tagctagcta tcttaaacaa gaacctatta
     6601 cagggtacca aaaggtatct tatgccagct taacccttcc tgtaaaggga ttacctgata
     6661 agcaaagtat ttccatttta tcaagttcaa ctacctctct tagcccctat tttaatctgc
     6721 tggatagtca ggagcaaaag aaggttccca ttccaacctc tggtgttttg atttctgaga
     6781 aattagcctc ctattacaag gtaaaaccag gtgatcagtt ggtattgact gatcggaaag
     6841 gacagtttta taaagtgacg attaaacagg ttattgacat gacagttggc cattacctga
     6901 taatgtctaa tacctatttt aagaatcatt ttaaaggatt ggaggctgct cctgcctatc
     6961 tgattaaggt aaaagacaaa gatagcaagc acataaagga gacagccagt gacttgttaa
     7021 ccttaaaagc gattagagca gtttcacaaa acgccaatca tattaaatct gttcagctag
     7081 tagtcacctc tcttaatcag gtcatgaccc tccttgtctt cttgtctatt ttattagtaa
     7141 tcgttatcct ttataactta acgactatta atattgctga gcgtattcga gaattatcca
     7201 ctattaaagt tctaggattt tacgatcagg aggtcacctt atatatttat cgagaaacta
     7261 tttcgctatc cctagtaggc attcttttag gtatctattt aggaaaaggc ctgcatactt
     7321 atatcatgac aatgatttca actggggata ttcaatttgg tgtaaaggtt gatgcttatg
     7381 tttatctagt gccaattcta gtaatcctta gcttgttagc ggtattaggt atctgggtta
     7441 atcgccattt aaaaaaggtt gatatgttag aagctttgaa atccatagat tgattggtga
     7501 aaagacagat atagacatca cttgaaaagt taatcatatt atgatagtat ctaaatacta
     7561 taatttaata gaaagatact atggatggaa aatagcattg aggcctatct agcagatagc
     7621 agagaaaagg taacattagg tacagttgtt gattgtttta aaggaaaagc agtctcaagt
     7681 aaggttgtgc caggtgatgt gggattgatt aatttatctg acatgggcac cttagggatt
     7741 caatatcacc aattaagaac tttccagatg gatcgtaggc agctcttgcg ttaccttttg
     7801 gaagacggag atgtcttaat cgcctctaag ggaaccctaa aaaaagtctg tgtttttcat
     7861 aagcaaaatc gagatgtggt ggcatcatca aatatcactg tcttacgccc tcaaaaactg
     7921 ttaaggggct actatatcaa gttctttttg gactcaccta ttggtcaagc gctcttggat
     7981 gcagcggacc atggcaaaga tgtgatcaat ctctcaacga aagaattgtt ggatattcca
     8041 attcccgtta ttcctttagt gaaacaggac tatttgatta atcactactt gagaggatta
     8101 acagattatc atcgtaaact caatcgagca gaacaggagt gggaatatat tcagaatgaa
     8161 attcaaaaag gattaggtta ggagtcttgt catgggttca gttgaacgta cattaaaaat
     8221 gaccttggct accattgttg ccattttaat tgcttaccaa cttcatctgg attatgcaat
     8281 gtcagcgggg atcattgccc tgttaagtgt tttagacacc cgtaagtcca gtttggtggt
     8341 cgctaggaat cgcttgctat cttttttcct ggctttcggg attgcgatga tgtgctttag
     8401 cttgtttggt tttacgacag taggttttat gtgttatttg ttaattatta ttcctttgct
     8461 ctatcacttt cagatagagg caggactggt tcctataaca gtacttgtaa cacatttgat
     8521 tgctaaaaaa agtattgcat tacctatttt atcgaatgag tttatgctct tttttgtagg
     8581 gactagtgtc gctttactat ttaatgctta tatgggtcca caagatcagc aaattcggta
     8641 ctatcaccaa aaagttgaat cggatctgaa aggtatctta taccgttttg aaagttttct
     8701 actggaagga aaaggtcaaa atgaagggct cttgatcaaa aaccttgata aaatattaga
     8761 tgaagctcta aaactagttt atcgagaaag gcataatcaa ctatttcagc agaccaatta
     8821 tcaagttcat tattttgaga tgcgacgaca acaaaataga ctattgggac aaatggctat
     8881 caacgtaaac acgttaatga gacaaagtaa ggaaagtatt cttttgtcac atctttttca
     8941 cgaaactgct tgtcagctaa gcgaacaaaa tccggcttta accttgattg atgacatcga
     9001 acaattgctt gaaacctttc gtcatggtga tcttcctcaa actcgggagg aatttgagcg
     9061 acgtgcggtt ttatttcagc tcttacaaga cttagagcgc tttatcttat taaaggtaga
     9121 gttttatcag gattatcaaa atgactaaat ctctattgca cacttcttat ctatgacagc
     9181 ttgggactta acttcctgag cttttttgct ataataaaaa gaagaatctc agaatggaga
     9241 caagatgaac gaaataaaat gccctcattg tcatacccta tttactatca atgagtcaga
     9301 gtatagtcaa ttattggaac aagtcagagg gcaagccttt gatgaagaat tgaaaaaacg
     9361 gctaatcaat gagatagcct tgctggaaga aaaagcgaag catcaattgc atgaggttgt
     9421 cgcaaaaaaa gaaacagcta ttaccagctt gacaaaccaa ttagagcaaa ttgaaaaaga
     9481 acaagcctac ctcagacaag aagaactggc taaaaaagac cagcttattg cttctttaga
     9541 agcgaaactt gataaattag cctcgcaaaa tgctttggaa ctggccaatc aattagctga
     9601 gaaggacaaa gaagtggtta gtttgaccaa tcagctggac aaattagcac ttgaaaaaga
     9661 tgccacgttc cagtcaaaac ttgctacaat cgaaaaagaa cgcgatggaa tcaaaaatca
     9721 attggcgctt caagctaaag aaagtgaatt gtcgttggct tcggtgcgca gcgactacga
     9781 agcacagtta aaagtggcta acgagcaagt tgaattttat aaaaatttca aagcgcagca
     9841 atctaccaaa gcaatcggag agagtctaga actctatgct gaaacagagt ttaacaaagt
     9901 aagaagctat gctttcccca atgctagctt tgtcaaagat aaccaattgt ctagtcgtgg
     9961 gtcaaaaggg gactatattt accgagaggt tgatgccaat ggtgtagaaa tcctctctat
    10021 catgtttgag atgaagaacg aggcagacac caccaaaaca aaacataaaa atagtgattt
    10081 tttcaaggag ttagataaag accgtcgcga aaaagattgt gagtatgctg ttttggtaag
    10141 catgttagaa gctgataatg attactacaa tacagggatt gttgatgtca gtcatgagta
    10201 tcaaaagatg tatgtggttc gtcctcaact ctttattcag ttgataggga ttctgcgaaa
    10261 tgcggccctg aatagtttac attataagca agagttggcc ttgattaagg aacaaaatat
    10321 tgacatcact cacttcgaag aggatttgga tcaatttaag aatgcctttg ctaagaacta
    10381 tcagtctgcc agcaacaact ttaaaaaggc tattgacgag attgataaat cgattaaacg
    10441 catggaggaa gtgaaacgct ttttaaccac tagtgaaaat cagttacgct tagctaataa
    10501 taaattagag gatgtttcag ttaaaaaact gacccgccaa aacccaacca tgcgagagaa
    10561 atttgaagcc ctcaaggacc agtaagcctg aaagtgagtc tttccctgct aaaattggtt
    10621 aagtgtttat tttggcaaaa ctgatgataa agcggtagaa tagaatcagt aataattact
    10681 aattagagag aaaaatagac atgataaatg gaatcattaa tttaaaaaaa gaagccggca
    10741 tgacctctca tgatgcagtt tttaaattac ggaagttgtt acaagaaaaa aagattggac
    10801 atggggggac cttagatcct gatgtggtcg gtgttctacc aattgcagtt ggtaaggcta
    10861 ctcgtgtgat cgaatacatg acagaagctg gtaaagttta tgaaggacaa gtgactctcg
    10921 gttactcaac aacgactgag gatgctagtg gagaggtagt tgcgaggtcc tctttgccag
    10981 ctgtgctaac agaagaactc gttgatcaaa cgatgacgac tttccttggg aaaatcacac
    11041 agaccccacc tatgtattca gccgtaaagg ttaatggccg taaattatac gagtatgcgc
    11101 gtgctggtga aagtgtggaa cgtcctagaa gagaagtgac tatttctctg tttgaacgca
    11161 ccagcccttt gaattttact gaagacggtc tttgccgatt ctcttttaaa gttgcttgta
    11221 gcaaagggac ttatgtgcgg accttagcag ttgatttagg tcgagctcta ggggtagaga
    11281 gtcatatgtc cttcttgcag cgatcagctt cagcaggatt aaccctcgag actgcctata
    11341 ctttgggaga aattgctgat atggtttcta aacaagagat gtcttttttg ttaccgatcg
    11401 agtatggcgt tgctgatctt cctaaaatgg ttattgatga tactgaatta actgaaattt
    11461 catttggtcg ctgtcttagt ctccctagtc aagagccact gttagctgct tttcatggcg
    11521 aaaaagtaat tgctatttta gaaaaaagag atcaagaata caaacccaaa aaagttctta
    11581 tttaaatagt ttgagtaagt agaatggata attatggaaa ttgaatatat caaagattat
    11641 cgtgatatta accaagaaga tgatacagtc ttggtattgg gatattttga tggattacac
    11701 cgtggtcata aagccttatt tgacaaagca agagaggttg caaataaaga agggttaaaa
    11761 gtagtcgttt ttacgtttac agagtctccg aaattggctt tttcgcgttt ttctcctgag
    11821 ttattgcttc atattactta tccaaagaag cgttatgaaa aatttgccga ttacggtgta
    11881 aataaattat atttggttga ttttacttct aaattctcta aggtctcatc tgatcatttt
    11941 ataactcatt atattaaaaa cctgaaagca aagcatattg ttgtcggttt tgactataag
    12001 tttgggcata attgtacaga tagtgattat ttaaccagaa attttgaagg acaagtttat
    12061 accattaagg aaataaaaga agatcatcga aaaatttctg ctacatggat aaggaagctt
    12121 attcaagaag gtaatgtagt taaagcaaac cacttgttag gctatgactt atcgacaagg
    12181 gggagagtcg ttcacgggga tgcgcgtggc cgtactattg gtttcccaac agccaatcta
    12241 gctccaattg acaacacata cttaccagct gatggagtct atgttacaaa tgttattgtt
    12301 gctaataaaa tctatcgctc tatgacgagt ttaggtaaaa atgtgacatt tggggggaaa
    12361 gagttgcgtc tagaagttaa catttttgac tttgacgaag agatctatgg agaaattatt
    12421 gagattgttt ggttagataa gattcgagac atggaaaaat tcgagggaat cgaagatttg
    12481 actgatagat tggaatatga taaacgaaca gcattaaatt ggaaaaaaga tagcaaatta
    12541 tcttaaattt ttgtataata aggtaagtaa atttgataga ggaaaaatat ggttacctta
    12601 tttttatcac ctagctgtac cagttgtcgt aaagcaaggg catggttagt aaaacacgaa
    12661 gttgactttc aagagcataa tattattaca agtccattaa gccgtgatga attaatgtca
    12721 atcctctctt ttacagagaa tggaacggag gatattattt caacacgttc aaaggttttt
    12781 caaaaacttg atattgatgt agaagagctt tcaatttcag atttaattga tttaattgct
    12841 aaaaatccaa gtcttcttcg tcgccctatt atcatggatc aaaaacgcat gcaaattggt
    12901 tttaatgaag atgaaattag agcgttttta tcgagagatt atcgcaagca agaactacgt
    12961 caagcaacga taaaagcaga aattgagggg tgatatgtca ggtaattatt attatccact
    13021 tgacttaagt tggagcactg aagaaatatc ctcagtgctt cattttttga ataaagtgga
    13081 gttagcatat gaaaaaaaag tagatgcaaa acaactccta gatagttata agacttataa
    13141 aaccattgtc aaaagtaaag ctcaggaaaa gcaaatcgac cgtgattttc aaaaagttag
    13201 tggttattcg acctatcaag ttgttaaaaa agcgaaggca attgagaaag gattcttttc
    13261 ccttggaaac taaatacgca tttgcaaggc aaatcattaa agaagcaggg ctttttatca
    13321 agtcaaaaat gtcagagcag ctagatattc aggtgaaaac acaatttgat gatctggtta
    13381 ccaatgttga tcaagaaact caacagttac tgatggatcg tattcatcag acctatcctt
    13441 gtgatgccat tttagctgaa gaaaatgacg ttcgtcaccc cattaatcaa ggaaatgttt
    13501 gggtcatcga tcccattgat ggaacggtta actttattgt gcagggatca cagtttgcag
    13561 tgatgattgc ctattatgaa caaggaattg gtcaatttgg gcttatttat gatgtgatgg
    13621 cagatcaatt actagctggt ggtggtgatt ttgaagttac tttaaacggt gataagcttc
    13681 cagattacca agaaaaacct ttagagcgta gcttaattgg ctgcaatgca ggcatgtttg
    13741 ccagaaatga tcgtaacctt gctcatctaa ttgcaaagac tttaggtgta agggtttatg
    13801 gtggtgcagg tatctgcatg gttaaggtca tgaagcagga attactggcc tatttttcat
    13861 ttatccaacc atgggattac gcagcagcaa aagtactagg cgataaactg ggttatgttt
    13921 tactaactat tgacggatat gagcctgatt ttcaaacacg tcaaaaaatc atgtttgttc
    13981 ctaaatgcca actcactagg atagcgtctt ttctaacaaa ggactctgcc gtcacacttg
    14041 aagatcaata gaaatgatgt cattaccaaa agaatttatt aacacttatc aagcaatact
    14101 aggcaaagaa ttagaagatt tcttggcaag ttttaaccaa gagccggtca atgcttttcg
    14161 gattaatccc ttaaagaatc aactaaaaac ctttgaacac cccattccaa ataccttatg
    14221 gggatattat ggtaaactat ctggcaagtc tccagagcat gtgtcggggt tggtttattc
    14281 ccaagaacca gcggctcaaa tggtggcaca agtagcggct cctcaaaagg ggagtcgtgt
    14341 tttagacttg gcagctgcac caggaggaaa atcaactcat ttattagctt atttagacga
    14401 tacaggtctt ttagtcagca atgaaatttc taagaagcgc agcaaggttt tagttgaaaa
    14461 tatcgaacgt tttggcgcta gaaatgttgt ggtgactaat gaatccgcag atcgtttagc
    14521 caaggtattt tctcattatt ttgatactat cgtctttgat ggaccatgtt ctggtgaagg
    14581 aatgtttcgc aaggaccctg atgctattca atattggcat cacgggtatc ccgcagaatg
    14641 cgccaagttg caaaaatcta ttttagaaga cgccttagtc atgttaaaac caggaggaga
    14701 attgatatac tccacctgta cttgggctcc tgaagaaaat gaagatgttg tgcagtggct
    14761 cttagagact tatacctttt tagaattggt cgatgttcca aaactaaatg gaatggttag
    14821 tggtatcgga cttccagaga ctgctagaat gtaccctcat cgttatcaag gggaagggca
    14881 atttgtggcc aagctaaaag ataagcgtca agaaggacaa agcactaaac taaaagcacc
    14941 taaatccaac ttgaccaaag accagttacg tctttggaaa atgtttgaaa aagaccatct
    15001 aaaccttacc ctatcaggaa cactacaaac ctttggtgat tacctatacc tcttgccaga
    15061 tggtcttcct gctttagatg gccttaaaat tgctcggaac ggtttagaat taggcgtctt
    15121 caagaagaaa cgctttgaac cctcttacgc cttgggatta gctttaaagc ctgatgaggt
    15181 ccgatcatct attgagctta gagaggaaga ctttagacct tatgtgtcag gtaacgtcat
    15241 tactttgccc caatcttatc caacaggctg gtaccaatta ctcattaatg gcaatggtct
    15301 aggatttgcc aaggtcgttg acaagaccat caaaaataat ttccctaaag ggttaagatt
    15361 ttagcgtaaa aaataagatt aaaaagttaa atatttaaag aaaaaatgct tt
//
LOCUS       DAUGSW010000033        14945 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUGSW010000033 DAUGSW010000000
VERSION     DAUGSW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14945
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.033"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            55..759
                     /locus_tag="VIB18_001303"
     CDS             55..759
                     /locus_tag="VIB18_001303"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEQ8766308.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVIAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            883..4608
                     /locus_tag="VIB18_001304"
     CDS             883..4608
                     /locus_tag="VIB18_001304"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEQ8766309.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFENYKADDFAAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDDVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLSQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNDETIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARITSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKDNFSQFEAIQAQHKIT
                     AASAVKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEKVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKDGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            4769..6223
                     /locus_tag="VIB18_001305"
     CDS             4769..6223
                     /locus_tag="VIB18_001305"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEQ8766310.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNPSCMGKVKE
                     ALNTVKGGFAYLLMTENRLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDSGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTVDEVCEIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6251..7273
                     /locus_tag="VIB18_001306"
     CDS             6251..7273
                     /locus_tag="VIB18_001306"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEQ8766311.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERARVMGVLGGFG
                     GMFDLSQTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYIATGKNNPVKLEEVVSGVAEGCVQAGVALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVKAALPLIKEELVNGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            7468..8022
                     /gene="purN"
                     /locus_tag="VIB18_001307"
     CDS             7468..8022
                     /gene="purN"
                     /locus_tag="VIB18_001307"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEQ8766312.1"
                     /translation="MKIAVFASANGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKVAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8206..9753
                     /gene="purH"
                     /locus_tag="VIB18_001308"
     CDS             8206..9753
                     /gene="purH"
                     /locus_tag="VIB18_001308"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEQ8766313.1"
                     /translation="MTKRALISVSDKSGIIDFAKELKNLGWDIISTGGTNVALDDAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTAQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPIDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9812..10936)
                     /locus_tag="VIB18_001309"
     CDS             complement(9812..10936)
                     /locus_tag="VIB18_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ8766314.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            11189..12454
                     /gene="purD"
                     /locus_tag="VIB18_001310"
     CDS             11189..12454
                     /gene="purD"
                     /locus_tag="VIB18_001310"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEQ8766315.1"
                     /translation="MKLLVVGSGGREHAIAKKLLVSKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWTFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVRPVLEGMIAEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGVKFAENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            12732..13223
                     /gene="purE"
                     /locus_tag="VIB18_001311"
     CDS             12732..13223
                     /gene="purE"
                     /locus_tag="VIB18_001311"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEQ8766316.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRVLSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            13210..14283
                     /gene="purK"
                     /locus_tag="VIB18_001312"
     CDS             13210..14283
                     /gene="purK"
                     /locus_tag="VIB18_001312"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEQ8766317.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPTNDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IFEKDFLANKAGVTVAPYKVVTSSLDLGGLDFTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIINEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVAQNPSAHLHMYGKLE
                     AKHNRKMGHVTVFSDLPDEVEEF"
     gene            14285..>14945
                     /locus_tag="VIB18_001313"
     CDS             14285..>14945
                     /locus_tag="VIB18_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766318.1"
                     /translation="MYLKYIFKIKDRNLVSDYESLVRNLTINLQKLVIKDITALIGDK
                     QLPITIYYRGENEKFPTGIVKVESDSVEGLELFDKTIKEIVGNESRFGKFTCIYDGIS
                     TYYSTEIYSELHEIERRTQEFLREAFFLSDKSGELKEYQATIKKMDSSDFSFSKLINE
                     IFKASDITDTFIDHVRACVEFGTVPNGDLLPKSFWDSLDNSLLDDKEQGLEINNLLNE
                     IR"
BASE COUNT         4287 a         2906 c         3503 g         4249 t
ORIGIN      
        1 ttttatagag tatgttactc ttaaatgaaa acagaaagaa aggcgaataa tcaagtgact
       61 aaccagctta tttataaagg aaaagcgaaa gatatttata gtacaaaaga tgaaaatgtg
      121 attagaacgg tctataaaga ccaagctact atgttgaatg gagctcgtaa ggagactatt
      181 gatggcaagg gagcactaaa taatcagatt tcatctctta tttttgagaa attaaataag
      241 gctggtgtgg tgacacatta tattgagcaa atttcaaaaa acgaacaatt gaataaaaaa
      301 gttgatatta ttccacttga ggtggtgtta cggaatgtga tagcaggctc attttcaaaa
      361 cgttttggag tggaagaagg acgtgttctt gaaacgccaa ttgtggaatt ttactacaaa
      421 aatgatgatc tgaatgatcc ttttatcaat gatgagcatg tgaagttttt gggtattgtt
      481 aatgatgagg agattgctta tctgaaagga gagactcgcc gtattaatga actcttgaaa
      541 ggttggtttg ctcagattgg gcttaacttg attgacttca agttggagtt cggatttgat
      601 caagaaggta caattatctt agcagatgaa ttttcgcctg ataactgtcg cctatgggat
      661 aagaatggta accatatgga caaggatgtt tttagaagag accttggcaa cctgacggat
      721 gtctatcaag ttgtacttga gaagttgata gcattgtaac tagaagagga aggaattgaa
      781 tccgttcggg aaactccgaa aaaaagatgg aacttactga aatctcaatt tcagatgtcc
      841 tcctattttc cagtcgctcc cttgtcggac ttggtatctt atatgaataa acgtattttt
      901 gttgagaaaa aggctgactt tggtattaaa tcggctagtc ttgtgaaaga gttgacgcat
      961 aatctacaac tgacctcttt gaaggctttg cgtattgtgc aggtctatga tgtcttcaat
     1021 ttggctgagg atttgctggc gcgtgctgag aagcatattt tctctgagca ggtgacagac
     1081 tgtcttttga cggaaactga aatcactgcg gagcttgata aggttgcctt ctttgccatt
     1141 gagtcgcttc ctggtcaatt tgaccaacgt gctgctagtt cgcaagaagc tttgctatta
     1201 tttggaagtg acagtcaggt taaggtcaat acagcccagc tttacttggt caataaggat
     1261 attacagaag cagagcttga agccgttaag aactatcttt tgaaccctgt tgattcgcgt
     1321 ttcaaggaca ttactttgcc gcttgaagag caggctttct ctgtgtctga taagacgatc
     1381 cctaatcttg atttctttga aaattataaa gctgacgatt ttgcggccta taaggcagag
     1441 cagggcttgg ctatggaggt cgatgacctt ctcttcatcc aagattattt caaatcaatc
     1501 ggacgtgtgc caactgagac tgagttgaaa gttttggata cttactggtc agaccactgc
     1561 cgtcacacaa cctttgaaac tgaattgaag aacattgatt tttcagcttc taaattccaa
     1621 aaacaattgc agacgactta tgacaaatat atcgccatgc gtgatgagct tggccgttct
     1681 gaaaagccac aaacacttat ggatatggcg actatctttg gtcgttatga gcgtgccaac
     1741 ggtcgtctgg acgatatgga agtctcagat gaaatcaatg cctgctcagt tgagattgaa
     1801 gtagatgttg atgatgtgaa agagccttgg ctcctcatgt ttaagaatga gactcacaat
     1861 cacccaacag aaattgagcc attcggtgga gcggcgactt gtatcggtgg tgctattcgt
     1921 gacccattgt cagggcgttc atacgtttat caggctatgc gtatttcagg cgcaggcgat
     1981 atcacgactc cgattgcgga aacacgtgct ggtaaattgt cacaacaagt tatttctaaa
     2041 actgcggcgc acggctattc ttcatatggt aaccaaattg ggcttgcgac aacttatgtg
     2101 cgtgagtact tccaccctgg ctttgtagcc aaacgtatgg agcttggagc tgtggttggt
     2161 gctgcaccta aggaaaatgt ggttcgtgaa aaaccagaag caggtgatgt ggtcatcttg
     2221 ctcggtggta aaacaggtcg tgatggtgtc ggcggtgcga caggttcatc taaggttcaa
     2281 acggttgaat ctgtggaaac agcaggagca gaggtacaaa aagggaatgc cattgaagaa
     2341 cgtaagattc aacgtctttt ccgtgatggc aatgtcactc gtctgatcaa gaaatcaaat
     2401 gacttcggtg caggtggtgt ttgtgttgcc atcggtgaat tggctgacgg tcttgaaatc
     2461 gatttggaca aggtgcctct taaataccaa ggtcttaatg gtactgaaat tgcaatctca
     2521 gaatctcaag agcgtatgtc agtcgttgtt cgtccaagtg atgtggatgc cttcatcgca
     2581 gcctgcaaca aggaaaatat cgatgcagtc gtagttgcga ctgtgactga aaaaccaaat
     2641 cttgtcatga cttggaatga tgaaacaatt gttgatttgg agcgccgttt ccttgatacc
     2701 aatggtgtcc gtgtcgttgt tgatgctaaa gtcgttgaca aggacttgac agttccagaa
     2761 gcacgcataa catcagcaga gacacttgaa gcagatacgc ttaaggtctt gtctgacctc
     2821 aaccatgcta gtcaaaaagg tctccaaacc atctttgact catctgttgg tcgttcaacc
     2881 gttaaccacc caatcggtgg tcgttaccaa atcacaccga cagaaagttc tgttcaaaaa
     2941 ttgccagttc aacatggtgt gacaacaact gcatctgtta tggctcaagg ttacaatcct
     3001 tatattgcag agtggtcacc ttatcacggt gctgcctatg ctgttattga agcgacagct
     3061 cgcttggtag caacgggtgc tgactggtct cgtgcacgtt tctcttacca agagtacttt
     3121 gagcgtatgg ataaacaggc agagcgtttt ggtcagccag tatcagctct tcttggttct
     3181 attgaggctc agattcaact tggtttgcca tcaatcggcg gtaaggactc tatgtctggt
     3241 actttcgaag acttgacagt accaccgacc ttggtagctt tcggcgtgac aacagcggac
     3301 agccgcaagg ttctctctcc tgagtttaaa gcggctggcg aaaacattta ctatatccca
     3361 ggtcaagcta tttcagaaga tattgatttt gaccttatca aggataactt tagccagttt
     3421 gaagctattc aagctcaaca taagattaca gctgcctcag ccgttaaata cggtggtgtc
     3481 ctagaaagtc ttgctctcat gacttttggt aaccgtatcg gtgcttctgt tgaaattgca
     3541 gagcttgaca gcagcttgac agctcaactc ggaggttttg tctttacatc agctgaggaa
     3601 attgctgacg cggtgaaaat cggtcaaact caggcagact ttacagtcac tgtcaatgga
     3661 aatgaccttg ctggcgctag ccttctagca gccttcgaag gcaaattgga agaggtttac
     3721 ccaacagaat ttgaacagac agatgttctt gaaaaagttc ctgctgtggt atcagatact
     3781 gttatcaagg ctaaggaaac aattgaaaaa ccagtggttt acattccagt cttccctggt
     3841 accaactcag aatacgattc agctaaggcc tttgaacagg ttggagctag tgtcaacttg
     3901 gtaccatttg taaccttgaa tgaggttgcc attgctgagt cagttgacac tatggttgct
     3961 aatattgcta aggcaaatat catcttcttt gctggaggtt tctcagcagc ggatgaacca
     4021 gatgggtctg ctaagtttat cgtcaatatc ttgcttaacg agaaggtccg cgcagctatt
     4081 gacagcttca tcgaaaaagg tggccttatc atcggtatct gtaatggttt ccaagccctt
     4141 gttaaatcag gtcttcttcc atacggaaac ttcgaagaag ctggtgagac aagtccaact
     4201 ctcttctata atgatgcgaa ccaacacgtt gccaagatgg ttgagactcg tatcgcaaat
     4261 accaactcac cttggttggc aggagttgag gtcggcgata ttcatgccat tccagtttca
     4321 cacggtgaag gtaaatttgt tgtcagcgct tctgaatttg cagagctaag agacaatggt
     4381 caaatctgga gccaatatgt ggactttgac ggacaaccat ctatggattc taaatacaat
     4441 ccaaacggct ctgtcaatgc catcgaaggg attaccagca aggatggtca aatcatcggt
     4501 aagatgggac actcagaacg ctgggaagac ggactcttcc aaaatatccc tggtaacaaa
     4561 gaccaaaccc tctttgcaag tgctgtaaaa tactttacag ggaagtaaaa aggttcagtg
     4621 aaccttttta gccctcgcct tgaattagtg aagggcgagg ttagaaagaa tctcgcttaa
     4681 tttttgagaa atagtaaaca cgggcgataa gttgtgcgaa aaactttcta ttttcgcttt
     4741 acttgacagc ctttgtatcg aggtaaaaat gacatacgaa gtaaaatctc taaatgaaga
     4801 atgtggagtc tttggtatct gggggcatcc tcaggcagct caagtcactt actttgggct
     4861 tcatagcctt caacatcgcg gtcaagaagg agctggtatt gtttcaaatg acaatgggaa
     4921 actctatggt tatcgaaatg ttgggctcct ttctgaagtt tttaagaatc aatctgaatt
     4981 agataattta actgggaatg cggctattgg acatgttcgg tatgctactg caggttctgc
     5041 agatattcgc aatattcagc cttttcttta taaatttcat gacgggcaat ttgctttatg
     5101 ccataatggt aatttgacaa atgctatttc tttaaggaaa gaattagaaa agcaaggtgc
     5161 aattttcaat gcctcctcag atactgaaat tttgatgcac ttgattcgtc gaagccataa
     5221 cccaagttgt atggggaagg taaaagaagc tctaaataca gtaaagggtg gctttgccta
     5281 tctactgatg acagaaaata gattaattgc tgctcttgac cctaatgcct ttcgtccttt
     5341 gtcaattgga caaatgcaaa atggtgcctg ggttatttcc agtgagacct gtgcttttga
     5401 ggtggtaggc gcaaaatggg ttagagatgt tgaacctggc gaagttattc ttatagacga
     5461 tagtggtatt caatgtgatc gttatactga tgaaacgcaa ctggcaattt gttcgatgga
     5521 atatgtctat tttgcaaggc cggattcaac tatacatggt gttaatgttc atacggctcg
     5581 aaaaaatatg ggaaagcgtc ttgcacaaga atttaaacag gatgctgata ttgtaattgg
     5641 tgtcccaaat tcgtccttat cggctgctat gggctttgct gaagaatccg gattaccaaa
     5701 tgagatgggt cttgtaaaaa atcagtatac gcagcgaacc tttattcaac cgacacaaga
     5761 attaagggaa caaggtgttc gaatgaaact atcagcggta tctggtgttg tcaaaggaaa
     5821 gcgcgttgtt atgattgatg actcaattgt aagaggaacg acttctagaa ggattgtcgg
     5881 attattaaga gaagcaggag ctagtgaagt ccatgtggct attggtagtc cagaacttaa
     5941 gtacccatgt ttctatggta ttgatattca gactcgtcgt gagttgattt cagccaatca
     6001 cacggttgat gaggtctgtg agattatcgg tgcagatagt ctgacctatc tctcactgga
     6061 tgggttgatt gaatcaattg gactcgaaac aaaagcacca aatggtggtt tatgcgtagc
     6121 ttactttgat ggacattatc caacgccgct ctatgattat gaagaagaat acctcagaag
     6181 tttagaagag aaaacaagtt tttatattca aaaagtgaaa taagctctgc taattatata
     6241 aggagaaaac atgtctgaaa aaaatgctta tgcaaaatct ggtgttgatg ttgaagctgg
     6301 ttatgaagtg gttgaaagaa taaaaaaaca cgttgctcgt acagaacgtg cgagagtcat
     6361 gggagttcta ggtggctttg gtggtatgtt tgacctgtca caaacaggag ttaaagagcc
     6421 tgtcttggtt tcagggactg acggtgtcgg aacaaaactt atgcttgcta tcaagtacga
     6481 caagcacgac acaatcggtc aagactgtgt tgccatgtgt gtcaacgata ttattgcagc
     6541 aggtgctgag ccattatatt ttttagatta tattgcgaca ggaaaaaata acccagtcaa
     6601 acttgaagaa gttgtttctg gtgttgcaga aggttgtgtt caagcaggag tagcactcat
     6661 tggaggtgag accgctgaaa tgcctgggat gtatggcgaa gatgattatg accttgctgg
     6721 ctttgctgtt ggtgtggctg aaaaatctca gctcatcgac ggttcaaaag taaaggaagg
     6781 cgatattctt ttgggacttg cttcaagtgg tatccattca aacggttatt ctttggtacg
     6841 tcgtgtcttt gctgactata ctggtaaaga gctgcttcca gaacttgaag gaaaacaact
     6901 taaggatgtc ctccttgagc caactcgtat ctatgttaaa gcagctctgc cattaatcaa
     6961 ggaagaacta gtcaacggta tcggccacat cacgggtggt ggctttatcg agaatattcc
     7021 tcgtatgttt gcggatgatt tggctgcgga aatcgatgag gacaaggtgc cagtgcttcc
     7081 gattttcaag gcgcttgaaa aatatggtga catcaagcac gaagaaatgt ttgaaatctt
     7141 caatatgggt gtcggtctta tgctagctgt tagtcctgaa aatgttaacc gcgtcaaaga
     7201 gctcttggat gaaccagttt atgaaatcgg tcgtatcatc aagaaagcag acgatagtgt
     7261 ggttattaaa taagtcacta aattttataa gaaaggagtg tttagttagt ttgcctaact
     7321 gaacacggga ttaaatttct aggaaaaaag ataaaacgac ttagacgcaa gcgtcgttgt
     7381 tcgtttttct atttttctac gaaatttttc ggcaagccga atcatccctt atttttcggc
     7441 aagccgaatc atccctttgt atcgaatatg aaaatcgctg tttttgcttc tgctaatggt
     7501 tccaactttc aggtcatagc agagcagttt ccagttagtt ttgtcttttc agatcatcgt
     7561 gatgcctatg ttttagagcg tgctcagaat ttagctattc caagcttcgc ttttgaactc
     7621 aaggagtttg agaataaggt ggcttacgag caagccatcg ttgatttgtt ggacaaacac
     7681 gagattgact tagtctgtct ggcaggctat atgaagattg ttggagaaac cttactcttg
     7741 gcctatgagg ggcgtattat caatattcac ccagcctacc tgcctgaatt tccaggtgcc
     7801 cacggtatcg aggatgcttg ggaagctggt gttgaccagt ctggcgtgac catccactgg
     7861 gttgactctg gtgtggatac cggtcaggtc atccaacaag tgcgcgtgcc acgcctagca
     7921 gacgatagcc tagaaagctt tgaaacccgt atccatgaaa ccgaatatca actctaccca
     7981 gctgtcttag atagcttggg agtggagaga aaagtaatct agcctttatc ttaaaatttt
     8041 aggtaaagtt aggaaagata gtaaagaaga attaacgttc caaaaagaaa ggaattgaac
     8101 ccgtctggaa ggcacagaaa aaagataaac atctcctagg cgcaagcgtc ttcgtcgagt
     8161 ttcctatttt tccttggcct tctagtcgga cttggtatct taaatatgac taaacgtgct
     8221 ttaatctcag tgtctgacaa gtcaggaatt attgactttg caaaagaatt gaaaaacttg
     8281 ggttgggata ttatctcaac tggtgggact aacgttgccc ttgacgatgc tggtgttgag
     8341 actattgcca tcgacgatgt gactggattc ccagaaatga tggacggtcg tgttaagacc
     8401 ctccatccaa acattcacgg tgggcttttg gcccgtcgcg atgctgacag ccaccttcag
     8461 gctgctaagg ataacaatat cgagctgatt gacctcgtgg ttgtcaacct ctatcccttc
     8521 aaggagacta tccttcgtcc agacgtgacc tatgatttgg cggtggaaaa tatcgatatc
     8581 ggcggtccat caatgcttcg ctcagccgca aaaaaccatg ctagcgtaac cgtagtggtt
     8641 gacccagcgg actatgcgac tgttttggga gaattagctg acgctggtca gacgacattt
     8701 gaaacgcgtc aacgcttggc agctaaggtc tttcgtcaca cagcagccta cgacgctttg
     8761 attgctgagt acttcacagc tcaagtggga gaggctaagc ctgaaaaatt aaccatcact
     8821 tacgacctta aacaggctat gcgttacgga gaaaatccac aacaagacgc tgatttctat
     8881 caaaaagcct tgccaataga ctactcaatc gcttctgcta aacagctcaa cggaaaagaa
     8941 ttgtccttca ataatatccg tgatgctgat gcagcaatcc gtattatccg cgatttcaaa
     9001 gacagtccaa cggttgttgt cctcaaacac atgaacccat gtggtatcgg acaggctgat
     9061 gatattgaga cagcttggga ttacgcttat gaagctgacc cagtttcaat ctttggtgga
     9121 attgtcgtcc ttaaccgtga agttgacgca gcgacagcta agaagatgca ccctatcttc
     9181 ttggaaatca tcatcgcacc atcatactca gaagaagcgc tagctattct cacaaataaa
     9241 aagaaaaact tgcgaatcct tgagttgccg tttgatgccc aagctgccag cgaagtggaa
     9301 gctgagtaca ctggcgtagt tggtggactt ttggtgcaaa accaagacgt tgtggctgaa
     9361 aatccatctg actggcaagt ggtgacagac cgccaaccaa cagaacaaga ggcgactgcc
     9421 cttgagtttg cctggaaggc tatcaagtat gttaagtcta acgggattat tattactaac
     9481 gatcacatga cgcttggact cggtgcaggt caaaccaacc gtgtcggctc agtcaagatt
     9541 gctatcgagc aggctaaaga ccaccttgac ggtgccgttc tagcatcaga tgccttcttc
     9601 ccatttgcgg acaacattga agaaatcgct gccgcaggga tcaaagcaat catccaacca
     9661 ggtggttcag ttcgtgacca agactctatt gacgccgcaa acaaacatgg cttgaccatg
     9721 atcttcacag gtgtgagaca ttttaggcat taataaaaaa atgtggtcta attaaaacca
     9781 cattttttta ttaaaagaaa atataagtta actataattt gttagcttta tcagcattta
     9841 cccatgttcc acgagatccg atttgaacat aaataccatt acttggttga tcaattttta
     9901 atactttata actaccagtg acggtaaaat attcacccac acggagaatt tgatctccta
     9961 aaacttttcc ttggttatct gtttcatcta atggtgtggg atcaatccag tttagtggag
    10021 ttgggtctcc tccggctaat tctttattaa cgatcaaatt attaacaagc tgatctacac
    10081 gaaaaacgcc agggaaggta acagtatcac cgaccttaat ggaaggtttt gtattgtcat
    10141 tttgaaccac agactgtgcg ggctctttaa tgggaatata gcgtcggttt ccagaaaaac
    10201 tgaggtagct aagccatgta taacctccag cagtcacgac tttatcgtaa taaacagatt
    10261 gacctgcttc atagtaagca agatcagggc tatcgatact ggtttgtcct ttgactggta
    10321 atctggttgt aaagtgataa gttccagagg ggtcaaatga agcttgagaa atgtgtttta
    10381 gttgtcttgg gtaggaatga cttgtctgag atgataagtc tttaaaatgg atataaccac
    10441 ttacctgaga ttttggaatt tgacgcttat ggtatctttc agggccttgt ccagcgttgt
    10501 aattatactc ttcgatagtg acagtgtctc cacggatatc agctacccat gctacatgac
    10561 cgtaagcagc atttgactga taagcgtttt tatcaaacca agcgatagcc cctatgcttg
    10621 gtgtcttatt cacaggataa ccctgatttt tcgcgatatg tccccacgtg caggcattac
    10681 cgtagccttt aggtaactga aaaccattag cagagcttaa acgaaaagct gcaaaagaag
    10741 tgcattggcg gatatacatg ttccacgaat cgattccatt gccttttttc cacttactcg
    10801 gatagttatc gcctaaaaca gctgcatgaa caagattttc ctgttgcgaa ataagtgtag
    10861 atggcatagt aggtactaga ccattaaaac ctaaaaggat tactcctgag accaaaaaac
    10921 gatgaaattt tttcattaat tacctcctgt aacttattat tcgaaagcaa gaaacaaaaa
    10981 atgttatttt tagatgatta ttttgaaaat tggctttact tgatattaaa taactatttg
    11041 attggctaat agagtgttcc ttatttcaag aattgtggtc tactatcaca tttttacaat
    11101 gtttcaatta ttgataacta atacattgta taaaaaagcg aacgtttatg atataatatc
    11161 taattataat acgaaagagg tggatgtttt gaaattactt gttgttggtt caggtggtcg
    11221 tgaacatgcg attgctaaga agttgttagt gtctaagggt gtggatcagg tttttgtggc
    11281 acctggtaat gatggtatga ccttggatgg tctggacttg gtgaatatag tagtttccga
    11341 acattccagg ttgattgcct ttgctaagga gaatgagatt tcttggacct ttattggtcc
    11401 tgatgatgcg ctagcagctg gtatcgttga tgatttcaac agtgctggac tcagagcttt
    11461 tggtccaaca aaggcagcag cggagctaga gtggtcaaaa gactttgcca aggaaatcat
    11521 ggtcaaatac aatgtcccaa cagcagccta tggcacattt tcagactttg aaaaagccaa
    11581 agcctacatc gaagagcagg gcgcacctat cgtggtcaag gctgatggct tggcgctagg
    11641 taagggtgtg gtcgtggctg aaaccgttga gcaggcggta gaggcggcgc aagagatgct
    11701 tctggacaat aagtttggcg attcaggagc gcgtgtggtt atcgaggaat tcttggatgg
    11761 cgaggagttt tccctctttg cctttgttaa tggtgataag ttctacatca tgccgacagc
    11821 tcaggatcac aagcgtgcct ttgacggaga caaggggcca aacactggtg gtatgggtgc
    11881 ctatgcgcca gttcctcatc tacctcagag cgtggtggat acagcggttg agacgatcgt
    11941 taggcctgtc cttgagggta tgattgccga agggcgtcct tatctaggcg tcctctatgc
    12001 ggggcttatc ctgacggctg atggtcctaa ggttatcgag ttcaactcac gtttcggtga
    12061 ccctgaaact cagattatcc tccctcgcct gacttccgat ttcgctcaga atattgacga
    12121 tatcatgatg ggcattgagc cttacatcac ttggcagaag gacggtgtga ctttgggtgt
    12181 tgtcgttgcc tcagaaggct atccactcga ttatgagaaa ggtgtgccac tgcctgaaaa
    12241 gaccgacggc gatatcatca cctactacgc aggagttaag tttgcggaaa atagcgagct
    12301 acttctctca aacggaggac gtgtctatat gctcgtcacc acagaagaca gcgtcaaagc
    12361 agggcaggac aaaatctata cccaactggc ccaacaagac acaacaggtc tcttctaccg
    12421 aaatgacatc ggaagcaaag ctataagaga ataagactaa ccattcaaat attagcgtca
    12481 gcaatcaacg accgaaggtc gctccaaaaa gaaagaagaa aggaactgaa cacgggacta
    12541 atttcctagg aaaaaaataa aactacctgg acgcaagcgt catcgttagt tttctgcgtc
    12601 gtaggcgtct gatgctaaag cacctagtcg ccctgacgtg ggttcgtctt cgaaatcaaa
    12661 gatttcggac ttaccgcata tttttctacg gaaagtttcg acaagtcgaa acgccccttt
    12721 gtatcttaat tatgaaaact ccaattattt ctattatcat gggctccaaa tctgactggg
    12781 caaccatgca aaaaacggct gaagttctag acaactttgg cattgcttac gagaagaaag
    12841 tcgtctctgc tcaccgtacg cccgacctca tgttcaagca tgctgaggaa gcacgtggtc
    12901 gtggcatcaa aatcatcatc gcaggagcag gtggggcagc tcacttgcct ggtatggtgg
    12961 cagctaaaac aacgctgcct gttatcggtg tgccagtcaa atcacgtgtc ctttcaggtt
    13021 tggattcgct ctattccatt gtgcagatgc ctggcggtgt gcctgtggca accatggcta
    13081 tcggagaagc gggagcgact aacgctgccc tgacagccct ccgtatcctt tctatcgagg
    13141 accaaaatct ggctgatgcg ctagctcatt tccatgagga acaaggaaaa atcgcagagg
    13201 agtcaagtgg tgaactcatt taagactatt gggattattg gtggtggtca gctagggcag
    13261 atgatggcaa ttgcggccat ctatatgggc cacaaggtca tcacgctgga tcctactaac
    13321 gactgccctg cctcccgcgt tagcgaggta attgtggcgc cttacgatga tgttgaggct
    13381 ttgggacaat tggctgcgcg ttgcgatgtg ttgacttatg agtttgagaa tgttgatgcg
    13441 gacggtttgg atgccgttgt gtcagcttgt cagctaccgc aggggaccga tctgctccgc
    13501 atttcccaaa accgtatctt tgaaaaagac tttctggcaa ataaggctgg tgtgactgtt
    13561 gctccctata aggtggtgac gtctagcctt gacctagggg gacttgattt taccaagacc
    13621 tatgtcctca agacagcgac aggtggttat gacggtcatg ggcaaaaggt tatccgctca
    13681 gcagaagatt tgccagaggc gcagcaatta gctaactcag ctcagtgtgt cttggaagag
    13741 tttgtcaact ttgaccttga aatctcagtc atcgtgtctg gaaatggaga ggatgtgacg
    13801 gtctttcccg ttcaggaaaa tatccactgc aacaatatcc tgtcaaaaac tatcgtgcca
    13861 gctcgtatct cagatcaact ggctgataag gctaagaaaa tggcggtgca gattgccaag
    13921 aaactccagc tgtcaggaac tctctgtgtg gaaatgtttg cgaccgcaga tgatatcatt
    13981 atcaatgaaa ttgccccacg tccccacaac tcagggcact actcaatcga ggcttgcgac
    14041 ttttcacagt ttgacaccca cattttgggc gtgctaggag cgccgctccc aaccatccac
    14101 ctccatgctc cagccgtcat gctcaatgtc ctcggacaac acgtccagca ggcaattgac
    14161 tatgttgccc aaaaccctag cgcccacctc cacatgtatg gtaaactaga agcgaaacat
    14221 aaccgcaaaa tgggacatgt gacggtgttt agtgatttgc ctgatgaggt ggaggagttt
    14281 taggatgtat ctaaagtata tatttaaaat aaaggatagg aatttagtat cggattatga
    14341 atctttagtt cgaaatttga caatcaatct tcaaaaacta gttattaaag atataactgc
    14401 attaataggg gataaacaac ttccaattac gatatattat cgtggggaga atgaaaagtt
    14461 tcctacggga atagtaaaag ttgaatcaga ctcagttgaa ggattagagt tatttgataa
    14521 aacgataaag gaaatagttg ggaatgaaag tagatttgga aagttcacat gtatatacga
    14581 tggaataagt acatattatt caacagaaat ttattctgaa cttcatgaaa ttgagcgtcg
    14641 aacacaagag tttttaagag aagcattttt tctgagcgat aaaagtggag aattgaaaga
    14701 atatcaggca actatcaaaa aaatggatag tagtgatttc tcattcagca aattaattaa
    14761 tgaaattttt aaagcaagcg atataactga tacatttatt gatcatgtta gagcgtgtgt
    14821 tgaatttgga acagttccaa atggagattt attaccaaaa agtttttggg atagtttaga
    14881 taactcttta ctagatgata aagagcaagg tttagagatt aataatttat taaatgagat
    14941 tcgtt
//
LOCUS       DAUGSW010000034        12678 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUGSW010000034 DAUGSW010000000
VERSION     DAUGSW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12678
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.034"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(9..578)
                     /locus_tag="VIB18_001314"
     CDS             complement(9..578)
                     /locus_tag="VIB18_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8766319.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(636..1181)
                     /gene="coaC"
                     /locus_tag="VIB18_001315"
     CDS             complement(636..1181)
                     /gene="coaC"
                     /locus_tag="VIB18_001315"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEQ8766320.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(1174..1866)
                     /gene="coaB"
                     /locus_tag="VIB18_001316"
     CDS             complement(1174..1866)
                     /gene="coaB"
                     /locus_tag="VIB18_001316"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEQ8766321.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNEHLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            2047..2898
                     /locus_tag="VIB18_001317"
     CDS             2047..2898
                     /locus_tag="VIB18_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEQ8766322.1"
                     /translation="MKGRIVITVRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            2895..4094
                     /locus_tag="VIB18_001318"
     CDS             2895..4094
                     /locus_tag="VIB18_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEQ8766323.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            4091..5089
                     /locus_tag="VIB18_001319"
     CDS             4091..5089
                     /locus_tag="VIB18_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEQ8766324.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEKAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            5131..5463
                     /locus_tag="VIB18_001320"
     CDS             5131..5463
                     /locus_tag="VIB18_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEQ8766325.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            5456..6268
                     /locus_tag="VIB18_001321"
     CDS             5456..6268
                     /locus_tag="VIB18_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEQ8766326.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            6261..7142
                     /locus_tag="VIB18_001322"
     CDS             6261..7142
                     /locus_tag="VIB18_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEQ8766327.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILGTKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            7189..8208
                     /locus_tag="VIB18_001323"
     CDS             7189..8208
                     /locus_tag="VIB18_001323"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8766328.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            8336..10006
                     /locus_tag="VIB18_001324"
     CDS             8336..10006
                     /locus_tag="VIB18_001324"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8766329.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIAIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            10091..11668
                     /gene="cls"
                     /locus_tag="VIB18_001325"
     CDS             10091..11668
                     /gene="cls"
                     /locus_tag="VIB18_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEQ8766330.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGIPYALAKTYYKALMSSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            12008..12346
                     /locus_tag="VIB18_001326"
     CDS             12008..12346
                     /locus_tag="VIB18_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766331.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
BASE COUNT         3938 a         2179 c         2631 g         3930 t
ORIGIN      
        1 aaagctaatt acctttttag tcttgatagt gttggaataa gtacaaaggt aataatagct
       61 gagatgatca tctcaacaat agcgtttgat gagatgatgg ctgttagtag tgctttaata
      121 tttccatcaa aaactgtcgc gaaaaaaata aatatcccag ataatacaaa tatagtattt
      181 gttagagaac caatgatacc ggatactatt aaaccaaact gattaggaat caatttatag
      241 caataataag gggtaatacc aatcaaaata cgtgggataa tagcaattat taaagaagcg
      301 aaagttccat gatcgacaaa aggtgaaaag agataatttg taggcagtag aatgatggta
      361 tttgtaatga cacttataat ccccattaat cctcctaaaa tagcacctat tcttgggcca
      421 tataagacag aagcaataat aactgggata tggacaagcg ttggtttgat tggaataggc
      481 caaatattaa agacaagact gctcacaaaa tgaatgacta acatgatggc aaaaaagata
      541 gcaatacgag aaatatctgc tgatttacgg tgattcattt tactctccaa aaaatataat
      601 acttaattct aaaaaggtga tcagaaaaac gactgttaaa gtttccaaat cgtatcaata
      661 gtagctaaga taacatcaat atcagccaaa gcaccaggtc ctttatctcc acaggctaat
      721 aagctagatt ttggaggaat ttctgtaaac cctattgtcg ataagcgttt aatattttct
      781 tgggtaatag ggttttgata cattttggta ttcatggctg gggctattaa ttttggtgtg
      841 gtagctggta gggcaagagc aacacttgtt acaatattat cagcgaatcc atatgctaga
      901 tgagcaatag tattagcaga ggcaggtgca acaataaata aatctgtgcg ttttgctaat
      961 tcgatatggt tgataacttt tgggtcatgc tcatccataa catctaaatg aatagcattt
     1021 tttgataaca cttgcagggt taatggtgta ataaattgtg tagcagcctg agtcattatg
     1081 atgtgaacat catagccaat tttagttaat tgactcgtaa gatctgctgc tttataggca
     1141 gatatactac cagaaacagc taaggtaata tgtttagtca tgtttggtca tcctttcata
     1201 taataagtca gcaattgcct ctttggtatc tgcagatgca acttcgttat tggatatcaa
     1261 aagagccttg tgcatacctg tttggatatc aactaaatca ttggcgagaa tataatcagc
     1321 atggttttta gctagacttg ctctggctac tttaattaac tcttcttgag gcacattaac
     1381 tagaagttta aagccgacta gtttaatatt aggattccac tgtttaacat aagagataac
     1441 tttgggtgtt tttttcaaaa aaagaacctg ataatcagat gcagatgaga ttttcggctc
     1501 actgttatgt tcacatagaa aacaattaag gttatcagct tgagagactt gttccaaatc
     1561 agtcatgtag actggagtat agtcagaaac agccatacta tgaattagaa tgtcatggtg
     1621 aggaacctga tctttgagtg cagccattaa gtcgttaact gtttccactt caataatcct
     1681 taggtgctca tttggcagag gtttagtggc tgttttagta gtgactaggg taacgtcatg
     1741 atgatattgt aaaaatcgct ctgtgattaa ttttccaagt tgcccagttg agtgattagt
     1801 gatacctcgt actgcatcta taggttcagt tgttccacct gatgttatta ttaatttcat
     1861 agtcatattt tatcaaaaaa ggagctgata gtaaacggaa gataatgacg ccagacattg
     1921 tcttgcgttt gtattaatat ggaatagtaa tagatttcta gtaattaaaa cgaagttctg
     1981 gaaagcaaga cactatagta gctaaaatct aaattttaag gtaaaataga gcaagcggtt
     2041 tcaagtgtga aaggaagaat tgtgataact gttagagatt tagcgtcact gccgattttt
     2101 gtttacggtg atggaaataa aaaagttcca ggagctttga gtccttttgt gtggacagag
     2161 gtgtttttaa aaactatcaa tcaagaacct aatcaactga tcttacatat ttggccgatg
     2221 acaagaacag ttatattagg aatgttagat agacagcttc cctactttga gctggctaaa
     2281 acagagattg gcaataatgg ttatgttcct gttactcgta atattggcgg tttggctgtt
     2341 gtcgctgatg atgggatttt gaatttttcg cttgttattc cagaccattt ttcggaatct
     2401 atcagtatta gtaatgctta tttaataatg gttgatgtca ttagagagag tttttcggat
     2461 tattatcagc gtattgaata tcacgaaatt aaaaattctt attgccctgg taattttgat
     2521 cttagtattg caggccgcaa gtttgcaggt atcgcccagc gtcgtatcaa aaagggaatt
     2581 gttgtgtcta tttacttgag cgtttgtggg gatcaagcag cgcgtggtca actcatcaag
     2641 gatttttatg aggccggaac acaaggagaa gttaccaagg ttaattaccc tcaaattgat
     2701 ccagaatgca tggcaactct ttcagaactc cttgagacgc cttttacagt ggcagaagtc
     2761 cttgaacgtc ttcgattgac cttgcgacag cttggctttt ccctcacgga aaaaagtcca
     2821 gatcaagcct tactgactaa ttttgatgct gtctatgaac ggatgcagct agaagtcgtc
     2881 agaaaggaag gcaaatgaaa gaaagattta gtcctttatt tgagcctttg actttgccaa
     2941 atgggagtca attggataat cgctttgttt tgtctcctat ggtgaccaac tcatccacaa
     3001 aagacggtta tgtcacccaa gatgatgtat cctatgcttt gagacgagca gcttctgccc
     3061 ctctacaaat tacaggagcg gcctatgtgg atccttatgg tcaattgttt gaatatggtt
     3121 ttagtgttac aaaagatgcc gatatttctg gcttgaaaga gctagctcaa gcgatgaagg
     3181 caaagggagc taaagctgtc ttacaactga cccacgctgg ccggtttgct agccatgcct
     3241 tgactaaata tggctttgtc tatgggccta gttacatgca gttgagatct ccccaacctc
     3301 atgaagtcaa acctttaaca ggtcagcaaa tagaggaatt gattgcagct tacgctcagg
     3361 ccactcggcg ggcaattcaa gcaggctttg atggcgtgga agtatcttcg gcgcagcgct
     3421 tattgattca aacgttcttt tcgacttttt cgaacaagag gacagatagt tatggttgtc
     3481 aaacactttt taatcgctct aagttaactc tagctgtttt gcaagctgtt caacaggtga
     3541 ttaaacaaga agctcctgat gggtttattt ttggatttcg tgctacacca gaagaaacta
     3601 ggggaaatga tattggttat agtattgacg agtttttgca gttgatggat tgggtactta
     3661 atgttgcaaa acttgattat ttagcgatag caagttgggg ccgtcatgta tttcgaaata
     3721 ctgttcgttc tcctggccct tattatggaa ggcgagttaa tcaggtagtt agagattatt
     3781 taagaaataa gctacctgtt atggctacag ggggaatgaa cacacctgac aaagctattg
     3841 aagcactagc tcatgctgat tttattggag tatctacacc ttttgtcgtg gatccagaat
     3901 ttgctcataa aatcaaagaa gggtgtgaag agagtattca tttaaggatt cgacctgctg
     3961 atttgaaaag tttagcgatt cctcaggctt ctttcaaaga tattgtacct ttgatggact
     4021 acggggaatc attgcctaaa gaatcaagaa ctttatttcg tagtcttact cacaattata
     4081 aggagattaa atgaaagtca gtattcttga ttatggggtg attgataaag aaaaaacacc
     4141 ccaagaagct ttattagaaa cgcgctgctt agcacaagta gccgacaaac ttggttttca
     4201 tcgtttttgg gtagcagagc atcataatat ttatgccttt gcaataagca gtccagagct
     4261 gttgatgatg catttagcag atcataccaa acagattcgg ataggttcag gaggtattat
     4321 gcctctacat tatagtagct ttaagattgc agaatggata atgactttag aggccttgca
     4381 ccctaatcgg attgatttag gtattggcaa ctctttagga actacgttag ttcaaagagc
     4441 tctatcaagt atccattgca aagacagcta tagtcaggtt gtcacagaat tataccagta
     4501 tcttaatcct gaccatttgt caccactacc gatttttgtt aaccctaggg gtaatactta
     4561 ccctcagatt tggacgctaa gcaatagttt ggagacagca gaactggctg gtcaattagg
     4621 tttaggctat acctttggta ttttccccta tataccaaaa gatcctataa cagaagctaa
     4681 aagagtatcg gcacattata gaaaggcttt taggccttca aagctattaa aaatccccaa
     4741 gttaatatta gcagttttta ttgtcctttc tgataccgac gagaaagcag aagctttggc
     4801 taaaccgttg gacatttgga tgcttggtca gcaagatttt aatgaattta agacctaccc
     4861 tgatgttgag gaggctagaa actatcactt aacagagaaa caaagagaag ccattgcagc
     4921 aaatcgtagt cgcatggtta ttggatcacc tcacacagtc aagaaacaat tggataggct
     4981 gatagaagct tgtcaagctg acgaattatt agccatcccc ttagttcctg aatttgccaa
     5041 tagacaacga accttagagc tgctagcaga cttatacgtg accatttaac cttaccaaaa
     5101 acaattccct aaactgaaag gaaagaaaca atgaaaaaaa ttgcaaatta cttattaatt
     5161 gagaaaacag atgaccgcta taccattagc atgacaccag aattacaaga cgatattggt
     5221 actattggtt acgctgaatt tacggataac gaccaccttg ccgttgatga cattatctta
     5281 aatctagagg cttctaagac cgtcatgtct gtcttgtcac cattggctgg ggcagttgtt
     5341 gagcgcaatg aggcagccac actaacacca acccttttga attcagaaaa agctgaggaa
     5401 aattggattg ttgtgctaac agatgttgat caagcagctt ttgatgccct agaagatgcc
     5461 tagttcattt gatttattag gggaaatgat tggtctgttg caaacagagc agcttactag
     5521 ttcttgggcc tgtcccttgc ctaatgcttt aacaaagcga caagacttgt ggcgggcgct
     5581 cattaaccag cgccctgctt tgcccttatc aaaagattac ttgaatctgg aagatgctta
     5641 tctagatgat tggcgtgctt cttttgttcc tgtatcagtc aaggattgcc aaaaaactaa
     5701 ttataccagt ctttttcttt accatgggga tattaggtac cttgctgtgg atgctattgt
     5761 caacgctgct aatagtgagt tattgggatg ttttattcct aaccatggct gtattgataa
     5821 tgcgattcat acgtttgccg gaagtcgttt acgcttagct tgtcaggcaa tcatgactga
     5881 acaaggccgt aaggaagcca ttggacaagc aaagcttacc agtgcttatc atctaccagc
     5941 ctcttatatt attcataccg tagggccaag aattaccaaa ggacaccacg tttctccgat
     6001 tcgagctgat ttgttagcac gttgttatcg ttctagtctt gatttggcgg ttaaagcagg
     6061 attgactagc ctagcttttt gctctatttc aacaggagaa tttggctttc ctaaaaaaga
     6121 agccgctcag attgctatta agacagtttt aaaatggcaa gcagaacatc cagaatctaa
     6181 gaccttaact atcattttta atacctttac atcagaagac aaggccttat acgacactta
     6241 tttgcaaaag gagaataact gtgagtaatt ggacaaccta tcctcagaaa aacctcaccc
     6301 aggcagaaca actggcccaa ttaatcaaag aagcagatgc acttgtagtt ggtattggag
     6361 ctggcatgtc tgcagctgat ggttttactt atatcgggcc gcgttttgag acggcattcc
     6421 cagattttat tgctaagtat cagtttttgg atatgctgca agctagcctt tttgattttg
     6481 aagattggca agaatattgg gcttttcaaa gtcgctttgt cgctttgaat tatcttgatc
     6541 agcccgtagg ccagtcttat cttgatttaa aagagatttt gggaaccaaa gactatcata
     6601 ttattactac taatgctgat aatgcttttt gggtggctgg ttatgatcct cataacattt
     6661 ttcacattca aggagaatat ggtttgtggc aatgtagcca gcactgccat cagcaaactt
     6721 ataaggacga tacggtcatc cgtcaaatga tcgcagagca aaaaaacatg aaagtcccag
     6781 gtcaactgat tcctcattgc cctgaatgtg aggcgccttt tgaaatcaat aagcgtaatg
     6841 aagaaaaagg aatggttgaa gatgctgact ttcatgccca aaaagcacgt tatgaggctt
     6901 ttttatcaga acataaagag ggtaaagtgc tttatctaga aattggtgtg ggacatacga
     6961 cgcctcagtt tatcaaacac cccttttgga aacgtgtctc agaaaaccct aatgccttat
     7021 tcgttacctt gaatcacaaa cattaccgca tccctctgtc aataaggcga caaagcctag
     7081 aactgacaga acacattgca caattgatta gcgccacaaa aaccatttac caaaaatcgt
     7141 aaccaaagcc aatagacggt taattaagag atagagaagg agactaacat gtaccttatt
     7201 gaaccgattc gtaacggtaa acgtatcacc gatggagctg ttgctctagc catgcaagtt
     7261 tatgttcaag aaaatctatt tttagatgat gatattttat ttccctacta ttgtgatccc
     7321 aaagttgaaa ttggaaaatt ccagaatgca gttgtagaaa ctaatcaaga gtatttaaaa
     7381 gagcatcata tccctgttgt tcgcagagat actggcggtg gtgccgttta tgtagattct
     7441 ggtgctgtta atatttgcta cttgattaat gataatggta tttttggtga ttttaaaaga
     7501 acctatcagc ccgctattga agcccttcat catttgggag caacagaggt tgaaatgtct
     7561 ggacggaatg acttggttat tgatgggaaa aaggtatctg gcgctgcgat gactattgct
     7621 aatggccgtg tttatggggg atattccctt ttgctagatg tggactttga agccatggaa
     7681 aaagcattaa aacctaatcg caaaaaaatt gaatcaaaag gcatcaggtc agttcgtagt
     7741 cgcgttggaa acatcagaga acatttagca ccacaatacc aaggtattac gattgaagag
     7801 ttcaaagatt taatggtttg ccaattgtta cagattgaga cgattagcca agctaagcgt
     7861 tatgatttaa cggaaaaaga ctggcaacaa attgatgctt taacagagcg taaatatcac
     7921 aattgggaat ggaattatgg caacgcgcct caataccgtt accatagaga tggccgtttt
     7981 accggtggaa cagtagatat tcatttagat attaaaaaag gctatattgc agcttgtcgc
     8041 atttacggag atttttttgg caaggcagac attgcagaac ttgaaggtca cttgatagga
     8101 acacgaatgg aaaaagagga tgtcttagct accctcaatg caattgattt agccccttat
     8161 ttaggtgcga ttacagcaga agaattagga gatttgatat tttcttgata aaaaagatac
     8221 ctcagaccgg taaagtgcga ttaaaaacga acaataattg ttttaattca aataaatgta
     8281 cgtatgatat gaattgtgat ataatgacgt cattacgtaa aattgaggag tcatcatgaa
     8341 atcagatatc gaaattgccc aaagtgtcgc cctacaacca atcactgaca ttgttaaaaa
     8401 agttggaata gacggcgatg acattgagct ttatggcaaa tataaggcta aattgtcttt
     8461 tgagaaaatg aaagctgtcg aagctaatga gcctggaaaa ttaatcttgg taactgctat
     8521 taaccctact ccagcgggag aaggaaaatc aaccatgtct attggactgg cagatgcctt
     8581 aaatcaaatg ggaaaaaaaa ccatgcttgc cttacgtgaa ccctcccttg gtcctgttat
     8641 ggggattaaa ggcggggcag caggtggtgg ttatgcccaa gtattgccta tggaagacat
     8701 taatcttcac tttactggtg acatgcatgc cattacaact gctaataatg cattatctgc
     8761 tttgattgac aatcatttgc agcaaggaaa cgatttagga attgatcctc gccgcattat
     8821 ttggaagcgc gtgttggacc ttaatgatcg cgctcttcgt caggtaattg ttggcttagg
     8881 tagtccagtg aatggtgtgc cacgcgaaga tgggtttgat atcacagtag cttctgaaat
     8941 catggcaatt ttatgtttgg caactgactt aaaagatcta aagaaacgtc ttgctgatat
     9001 cgtcgtggct tatacctatg atcgtaagcc tgtctatgtg cgtgacttga aggttgaagg
     9061 agcattgaca ttaattctaa aagatgctat caagccaaac ttggtgcaga ctatttatgg
     9121 aacaccagct cttattcatg gggggccatt tgctaatatt gctcatggtt gtaattctgt
     9181 ccttgctacc tcaacagctt tgcgattagc agattacact gttaccgaag caggattcgg
     9241 ggccgaccta ggagctgaaa aattcctaaa tatcaaagta cctaatcttc ctaaagcacc
     9301 agatgctatt gccattgttg caaccttgcg cgcccttaaa atgcatggag gtgtcgccaa
     9361 atcagattta gccgctgaaa attgtgaggc tgttcgctta ggatttgcca acttaaaacg
     9421 tcacgtggaa aacatgcgcc aattcaaagt tccagttgtg gtggctatca atgaatttgt
     9481 agcagatacc gaggctgaaa ttgctacctt aaaagcgctt tgtgaagaga ttaaggttcc
     9541 agtagaatta gccagtgttt gggcaaatgg agctgaggga ggcttagcat tagctaaaac
     9601 agtggttcgt gtgattgatc aagaagctgc tgactacaaa cgtctctatt cagatgagga
     9661 tactttggaa gaaaaagtga tcaatatcgt tacccagatt tatggtggca aagctgttca
     9721 atttggcccc aaggccaaaa cacaattgaa gcagttcgca gaattcggtt gggataaatt
     9781 gcctgtttgt atggctaaga cccaatacag tttttcagat aacccatcct tgcttggagc
     9841 gccaaccgat tttgacatta ccattcgtga atttgttcct aaaacaggag caggttttat
     9901 tgttggttta acaggtgatg tgatgaccat gcctggtttg cctaaagttc cagctgccat
     9961 ggcaatggac gtagcagaaa atggcacagc tctcggtctc ttttaggaaa aattgctcga
    10021 ataattcgag caagcgctcc tttcttcccg ctttactgtg atataataag gtaaatgaga
    10081 ttttggaggg atgattatca aaaagaaagc aaaagtaaaa tatttgctcc ataaagggaa
    10141 acatggattt ttaagaggaa tttttagtag aacaacaatc attgtattat taattatttt
    10201 gcaattagtt ttcttatttc aatcttatgc ctggatggag cagtaccgtg tttggataac
    10261 gattcttgaa agtgtctttg ctattactat tgttttatat ttagttaata gtgatatgga
    10321 tgctatttca agaatgacgt ggttaatttt gattatgatt gctccattac tagggtcact
    10381 gtttttaatt tatacaaaat tggattgggg ttacagaggg ctaaaacaga gaataaatca
    10441 tcttgtagat ctgtctgcac cttaccttag cgatgatgac gctatattag aggtattaaa
    10501 ggatagcaca tcaaccacat atcatttagt acagtactta gaaagaagtc gtggcaactt
    10561 tccgatttat aataatacaa gggtaactta cttcccaaca ggtgaaactt tttttgatag
    10621 tttaaaagaa cagttattct tagctaaaaa gtacattttt cttgaatttt ttattattgc
    10681 agaaggccaa atgtggggag aaatccttag tattctagaa aaaaaagtca gtgaaggtgt
    10741 agaagttagg gtgttgtttg atggcatgaa cgaactatca acgctatcat cagattacgc
    10801 caagagatta gaacaaatag ggattaaagc taaatcattt ttaccgatct caccctttat
    10861 ctctacctat tacaattatc gagatcatcg aaaaattgtc gttattgatg gggaggtatc
    10921 attcactgga ggtattaatc tagcagatga gtacattaat gaagtagagc gttttggcca
    10981 ctggaaagat gctggtttaa tgcttgaggg tgaagcaaca gacagctttt taattttgtt
    11041 tttacaaatg tggtctatca cagaaaaaga actgattatt gatccttatc tttcagatca
    11101 ttctttaaaa cttccttcag atggctatgt tattccctac ggtgattccc cgcttgatac
    11161 tgataaaata ggtaaaaatg tttatataga cattttaaat catgctaaag agtacgttta
    11221 tatcatgaca ccttacctta ttttagatag cgagatggaa cacgctttac ggtttgcatc
    11281 agaacgtgga gtagatatcc gaattattat gccaggagtg ccagataagg ggataccata
    11341 tgccttagct aaaacctatt ataaagcttt gatgtcttct ggagtaaaaa tttatgagta
    11401 tcaaccaggg ttcgttcatt caaaggtatt tatctctgat aatacaaaag cagttgtcgg
    11461 aacaattaac ttagactatc gtagccttta tcatcatttt gaatgcgcga cttatttata
    11521 tcgtgtgtca gttattgctg atattgtgaa tgactttaat gaagctcaaa agcaatcact
    11581 attgatgaca tcagatcatt tgacgcaacg tccttggtat caaaaattga taggattatt
    11641 agtacgaaca attgcccctc tcttgtaatt ttcgtaaaat atgttataat ttctgtatgc
    11701 gatgagtcga ttgtgactgc aaagtcactt ttgcgcaggg gaggtcatta aggcgggaag
    11761 ccgactttga taatctgtgt gaaccatttt atcacaatct tatttattaa gaatgcccct
    11821 tggattgaga tattctcaat ccttttttta attttattaa cttagttaaa attcagaatg
    11881 tatcagtgat tactgtgttt caaaataaga aagtagtttt tcgggtatga gtgctatgac
    11941 ttgacaaatg ctaataacat ttgcataatg taagtagaga tgaaaactta tgaaaagaga
    12001 tgatcttatg caaattatta agcgtgatgg ccacgttgct gattttgatc cagataaaat
    12061 ttatcaagca attattaaag cagcaaggac ggtctatgtt attgatgaca cgtggcgaca
    12121 aaacttaaca catgtcacta aaaaagtagt tattgattta gaagaagcac atgtagaacg
    12181 tcctactatc aatatggtcc aatcccttgt ggagaatcgt ttgatggatg ctggatatat
    12241 taccattgca gaacattaca tttcttatcg tcttcagcga gatttagagc gcaatggcta
    12301 tggtgataag attgtggttc acttgcgttt tgaacaaata aaataaaaac gcttctaatg
    12361 gcattttagt gtctttgagg ggataaggtt taaataccta acagataaaa atctgttagg
    12421 tatttttttg ctactattag gtgtattcta tattacatag aacttaagca ttcaagcttt
    12481 agtttaactt tctgtttatt ttttgctaca ttttgggaaa ctcccctcct ttcttagttg
    12541 aggtgaataa acttttattt gataaatcat atccttagtc ttaatgaaac agtctaagat
    12601 aatactactt cgaagtgaca gctagtagtt tccaattttt aagtagtcta aaatgatgtt
    12661 tttttaattt caaaacca
//
LOCUS       DAUGSW010000035        12641 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUGSW010000035 DAUGSW010000000
VERSION     DAUGSW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12641
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.035"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..776)
                     /locus_tag="VIB18_001327"
     CDS             complement(<1..776)
                     /locus_tag="VIB18_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEQ8766332.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAETSTLTQ
                     AQRAEKIKKIKEHIAKYPKTAEDRFWYSTFWGRRFDDNLYQEKLDEFTQRALNDIVDL
                     IEKGATQGPAGPKGERGPAGPEGKQGKPGEKGAKGDKGEAGAPGKDGAVGAQGPKGDK
                     GDTGERGEKGDTGAQGPQGEAGKDGAPGKDGAPGEKGEKGDRGETGAQGPVGPQGEKG
                     ETGEQGPAGPQGEAGKPGEQGPAGKPGEKAPEKSPEVTPTP"
     gene            1160..1642
                     /gene="nrdI"
                     /locus_tag="VIB18_001328"
     CDS             1160..1642
                     /gene="nrdI"
                     /locus_tag="VIB18_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8766333.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            complement(2036..2854)
                     /locus_tag="VIB18_001329"
     CDS             complement(2036..2854)
                     /locus_tag="VIB18_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEQ8766334.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILFSAMDDETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLDWR"
     gene            complement(2937..5123)
                     /locus_tag="VIB18_001330"
     CDS             complement(2937..5123)
                     /locus_tag="VIB18_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8766335.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAIIVNLHLLFALTIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDLINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQTRPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPEVNMSQLT
                     SKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL"
     gene            complement(5481..6230)
                     /locus_tag="VIB18_001331"
     CDS             complement(5481..6230)
                     /locus_tag="VIB18_001331"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEQ8766336.1"
                     /translation="MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLTDEAEVVLVFDDG
                     VKYLAKVTSSMAHELEIIETLPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEQKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEIPQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            complement(6230..7183)
                     /locus_tag="VIB18_001332"
     CDS             complement(6230..7183)
                     /locus_tag="VIB18_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEQ8766337.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            complement(7254..7724)
                     /locus_tag="VIB18_001333"
     CDS             complement(7254..7724)
                     /locus_tag="VIB18_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEQ8766338.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEAASYPYPRY"
     gene            7924..9681
                     /gene="pabB"
                     /locus_tag="VIB18_001334"
     CDS             7924..9681
                     /gene="pabB"
                     /locus_tag="VIB18_001334"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEQ8766339.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKTLDQVGPVIENVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDGITIP
                     NQWVSATQKKAYQKAIETIHREMQQGNTYQVNYTIQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNTWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTSTIVGDLKANCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPNPRGIYCGTVGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFL
                     EQHLNRLKEAATYFAYPYNEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFIQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            9714..10280
                     /locus_tag="VIB18_001335"
     CDS             9714..10280
                     /locus_tag="VIB18_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEQ8766340.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADA
                     LVLSPGPGWPKEANQMPKLIQDFFQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            10313..11581
                     /locus_tag="VIB18_001336"
     CDS             10313..11581
                     /locus_tag="VIB18_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEQ8766341.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTSTNGDLRSAYNSLDLAVMSTSPNEDGSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            11670..11866
                     /gene="ssrS"
                     /locus_tag="VIB18_001337"
     ncRNA           11670..11866
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VIB18_001337"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            11867..11939
                     /locus_tag="VIB18_001338"
     tRNA            11867..11939
                     /locus_tag="VIB18_001338"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11900..11902,aa:Lys,seq:ctt)
     gene            12153..>12641
                     /gene="smeZ"
                     /locus_tag="VIB18_001339"
     CDS             12153..>12641
                     /gene="smeZ"
                     /locus_tag="VIB18_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal mitogenic exotoxin SmeZ"
                     /protein_id="HEQ8766342.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKDGDKIAMFSVPFDWNYL
                     SEGTVIAYTYGGMTPYQEEPISKNIPVNLWINGKQISVPYNEISTNKTTVTAQEIDLK
                     VRK"
BASE COUNT         3541 a         2937 c         2486 g         3677 t
ORIGIN      
        1 ggcgttggtg tcacttctgg gctcttttct ggagcttttt cgcctggttt gcctgctgga
       61 ccttgctcac ctggtttgcc tgcttcgcct tgtgggccgg ctgggccttg ttcgcctgtt
      121 tcaccttttt caccttgtgg gcctactgga ccttgagctc cagtttcacc gcggtcacct
      181 ttttcaccct tttcgcctgg agctccgtct ttacctggag cgccatcttt accagcttca
      241 ccttgtgggc cttgagctcc ggtgtcacct ttttcaccgc gctcaccggt atcacctttg
      301 tcgcctttag gtccttgggc accaactgcg ccatctttac ctggggcacc ggcttcaccc
      361 ttatcacctt tagcaccttt ttcaccaggt ttaccttgct tgccttctgg accagctggg
      421 ccgcgttcac ctttaggacc ggctgggcct tgtgttgcac ctttttcaat caagtctaca
      481 atatcattaa gtgctctctg agtaaactca tcaagttttt cttgatataa attgtcatca
      541 aatcgtctac cccaaaaagt gctataccaa aatctgtctt cagctgtttt tggatatttg
      601 gcaatatgtt ctttaatttt tttaattttc tcagctctct gcgcctgcgt cagagtagaa
      661 gtctcagcct taacgctgct tgccccgcct ccaaaggcta gaaggacggc agcggctgag
      721 gttagcccgt agcgccagac cagtttgttg agattatggt gctttgatgt caacatatgt
      781 tgttctctct ttctttattt agatggtgtg ttttagataa aataacatgg tagctagacc
      841 tgattattta taatagtatt ataatagagt gtgaaaacga ttgtaaagtt ctcttttgtt
      901 gttcatcttt tagattttga ctgatcgctc ttttgtggag atcagagggc cactttggca
      961 cttgcctgcc tcgtttttaa gtcgaggggg catccggatc ctttctttaa ggtcactctt
     1021 ttttgaaatg ttgctttttt tgactgcttg taccttcttg tctggttgga taccgctagg
     1081 tttcttcttt acttgtttgt tggtcttgat tgtggtaagc ttatgaagaa accttgtagg
     1141 ataaaaaaag gagacactta tgcctcagat tacccttgtt tttattagcc tcagtggcaa
     1201 cacccttagc tttgtcaagc ggctatccct ttatctagca gacaattacg attaccatgt
     1261 caaacagatt aacattaaag atttgaagca cgagactttt cccgtcaaag aagagtttgt
     1321 ggcgattcta cccacttatc tagaaggcgg aaatggcgtt gactctggtg aggtggagat
     1381 cctcaccact cctttgggag agtttattgc tgcccatggc aatgcccagc gttgtcttgg
     1441 gattattggt tcaggcaaca aaaactttaa ccatcagtat tgcctgacag ccaaacagta
     1501 tgccaaacgc tttggctttc cactgctagg tgattttgag ctgcgaggga ctcctgatga
     1561 catttcgcgg ttagcccagg tcatcatgga ggccagctcc agacactcgt ctaacgacac
     1621 acagacattg cctaacagct agacagtcta tagatgatca tagctgtttt aaaaaagagc
     1681 gcttttagga caataactac agaggtctct taccctacgc cttgtgattt ctcagccttt
     1741 gaagaggtgg tccatggtgc ttcgtggggc ttgggatcac accaagcact cctagaaata
     1801 cccccatgca gactttagca aggcagctat acgcttggtg gtactttctg tgaagctcag
     1861 atggttggtg acaaaaaagc cctggttttc taaggtcact gatatgacta aagaggtcta
     1921 accagctcaa gatagagctg gttagacctc tttgtgttct cctaatcccc ctagacgatc
     1981 gcagtttctt atgtgtcttg gtttctccta tgtggtgtgc ctgttagcac atgctctaac
     2041 gccagtctaa tgtcacttct aaaccatagt ggtcactgac gactggcgca tccccgcctt
     2101 caaaggtaat cttagaagat cggatgatga agtccttgct ggtaaagaca tggtctacct
     2161 tgagggcttc tttgttacct tgccagccat caatatcagc cacgatgcta tgatcaccaa
     2221 acacatggtc agcaacctta tggctatctt gtaggtctag ggggctaccc atcatcactt
     2281 gataaccgtc ttgatccgtt ggattgttaa aatctcccat aagtagcaag ggacagttta
     2341 gtgtgagcag ttctttttct aatttctccc actcccctaa aaaccccttg tcaaaccaag
     2401 ataggtgcac attgacaaca gcgacttctt tgccatctaa cgtggttttg gctatgagtg
     2461 agcgtctggt gtggtagtct gtttcatcat ccatcgctga aaagagaata tctgaaacat
     2521 gaataggttg ttttgataag attgccacgc cttcctggta aatgtcatag ccaatatggt
     2581 tataagccca agaccaataa tagtgctgcc ctcgtttttg taaataatgg atcaagagca
     2641 gggcaaaatg gtctttatga atgcttggtg tccctgaaag agcttgatat cttggtaaat
     2701 ctgtggccag ctcgctctcg attaactgat tgatttcttg caagcaaatg atatcgtatt
     2761 tttcagctaa aatatgctca gccaaagcaa ctaatttttt aagagtgttg gcttgcatcc
     2821 acgaatgagt attcagtgtt aataccttgg tcattaatcc tcctttataa gacaagaaga
     2881 gccatagggc ctaaaccagc tatggctatt acctatcact atctcgtgat gttttgttaa
     2941 agttctacgg tagctacttt agtcttagca ggctgagctc ctaaagatgt caaggtcaca
     3001 tcttggatct ctgttgtgtt ggtaaaagca acaacaatgg ttgtttcacg ctctgctgat
     3061 ttaatagcag caagatctgc tacgactaat aggtcacctg catgaacccg ttgcccttct
     3121 gagactttga ctgaaaaagg cacaccattt aaggcgacgg tatcaagtcc cacgtgcacc
     3181 agcacttcaa gaccattatc tgtcagtaaa ccaaaggcat gcttggtcgg aaagacactg
     3241 gtcacaaggc cagctacggg tgcatagata ttaccatggg ttggttcaac cgcaaaccca
     3301 tctcccatca tcttagccgc aaacacctgg tctttcacac ctgtgattgg gagaaccatc
     3361 ccgtctgcca ctgatagcac ttcttctgtc acgtgtttaa aatcttttgc gggagtcggt
     3421 ttgctagtga gctgtgacat attgacttct ggaataacag cccctgagtc cagcaaatct
     3481 tgaatatctg atttcaaaat atctgcttta ggtccataga ccgcttgaac gccattgcct
     3541 ttttggatca agcccatagc gccagctttt ttccaatcgt cctcagcgcc aatcttagcg
     3601 gggtctttga ccgtcactcg taagcgcgtc atacaagcat caacatcatc aatattgcct
     3661 gccccaccaa ggagattaat gatttgtacg acttgagagt tgctatctgc tacttgggta
     3721 ggtcttgttt gagtgttacg gtcacccagt atatcggcat cgtagttgcc taaacggcca
     3781 gctgttgcga gatgcatttt cttgatcatc atatccgcaa taaagtacat gataactgca
     3841 aagaggatag aaacccaaac aaagttaatc aaatccatgc ctaggcctgc tttaagggcc
     3901 ataggggtgc gggttagtag ctctatattt ccaaatgagt gaacacgaag gttcacaagg
     3961 tcagccatgg caaatgaagc tccttgaaca agggcataga cgatgtaaag tggcattgct
     4021 gcaaacataa ataggtactc aagtggctca gttacccctg tcaaaaagac cgctgccgct
     4081 gctgagatga acatcatttt gtatgtgtgt tttttatcgg catccacatt acggtacatg
     4141 gctaaggcaa cccccatcaa tgttccggta gctccaatca tttgtcctac cttaaagcga
     4201 gctggagtca cactatccat taagtgacta taggctgaag cgtctgatcc tttaaggtga
     4261 acaaggtcag ttacccaagc aagccacaaa gggtcttgac caaatacttt tgtccccgct
     4321 gctgcacctg tcatgacctc ataagttcca ccaagagctg tatagttcat tgggatcgtc
     4381 aacatgtggt gaagaccaaa tggcaacaag agacgttcca aggtaccata taggaatggg
     4441 gctaggattg gagctgaatc ttgtgaagag gcaatccaca tcccaaaact gttaatccca
     4501 gactggatca ccggccaaac aacaaccaaa ataagggcta caaaaataga acgtaaaata
     4561 acgacaaatg gtacaaaacg cttcccatta aagaaggtca aaacttcagg aagtttacgg
     4621 taattatagt atttgttata ggccgttgct cctacgaacc ctgcaataat cccaacaaaa
     4681 acccctgtgt ttaaagctgg agattccaag acactggtga aataatcttt aacgatcatt
     4741 tgagtgccaa ggaggcttgt gatttttgct tctggatcag ctagcatagt actagacacg
     4801 ccataaaaag cgcctgttat ccgattgatc aagacaaaag caagacctga agcaaaggct
     4861 cctcctgcac gttctttagc ccaactacca ccaatggtca aggcaaatag caagtgaagg
     4921 ttaacaatga tagcccaacc aatctgagca ataatgtttc ctagagatgc caaaaatgct
     4981 gagtcgtggt taatcattgg aatagagttt ccgatactga tcattaaacc agctgctggc
     5041 atgacagcaa taacgaccat aagacatttc ccaaattttt gccaaaattc gaaacgaaac
     5101 agttgcttga atgatgtttt cattctatct ctcctttatt atcccctttt agccatagct
     5161 gcccttaagg cgcttttgtg acacaatgat atagactaca actcagcgat gcaatcgctt
     5221 gcattgatct gataccttta ttatactagt ctcgcaacaa tttgtaaagc gttttcttag
     5281 acagatgtta gtcgtttttc ttcattaata tagtagtgta actcaccaaa aagatgacaa
     5341 gagcccattt ccttttttgg tgatgagccc atcaacgatc ttcaaaaaaa caagaaacaa
     5401 taaaaaaagg ccgttgacac aatcgtgaac tgcctgttcg tttctttagc ctcttctttc
     5461 taaagtaagc aacagcctac ttattttgat gcctgcaatt ccaaagcata actaagagca
     5521 cttaaggcat atagcggcgc tgtctctgct cgcataatgc gagggcctaa gcccaccttg
     5581 atggcacctg ctgcctcaaa ctgagggatt tcagttgggg aaattccccc ttctggtcca
     5641 aagataaaga ggatttttgc ccctggctta acttctttta cttcacgcgc caaggtcgct
     5701 agctgacctg ccttagctgt ttcctcataa gcaatgaaga tatgatcaaa gctagaaagg
     5761 ctttttagaa actctgcttt ctgttcaaaa aggtgaactt caggcaccct atttcgtttg
     5821 ctctgctcag ccgctcctaa tacaatctta gccaatttgt cttctttttt agctaatttt
     5881 ttgccatccc atttgaccac tgaccagtct gctgggtagc cccatagcgc actggctccc
     5941 aattcagtca ctttctgggc aatcgtatct aacttatcgc ctttaggaaa tccagaagca
     6001 atagtcacct taacaggcaa ttccacctga tctggcaagg tctctataat ctctaactca
     6061 tgagccatac tactggttac cttggctaaa tacttcaccc catcatcaaa gaccaagaca
     6121 acttctgcct cgtcagtcaa gcgcatcact tgaaacatgt gcttgatggt atctttatcg
     6181 gtaattgtta cctttttttc tgctttgcct ttaataaaat actgttgcat tagccgccaa
     6241 tcactcctga gatatcatct gtttttttaa agacaagggc attccactcg ccttgaacca
     6301 tgtgagtttc taagaaaaag cctgcgctaa aggcagcttc cagaaccata tccaatttct
     6361 cagaaatgat gcctgataag ataaggtaac cttccttttt gaccaaacgg taagcatcat
     6421 cagtcaataa gactaagata tccgccaaaa tattagctac gatcacatcc gcttcttggc
     6481 taaccccttt taaaaggtcg ccagcagcca catgaatgtt gtctgttcct tgattcaaat
     6541 caatgttttc ctgagccact cgaacagcca catcatctaa atcataagca tagatggttt
     6601 tagcacctag taaggaactg gcaatcgaga ggacacctga tccggtccct acatcgataa
     6661 ctgtctcacc accacgaagg acttgttcca aggcaaaaag gctcatctta gttgtgggat
     6721 gtgtccctgt cccaaatgcc attccaggat ctaatttaat aaccttttcc ccagcagaag
     6781 cgtcataatc tgtccaacta gggacaatgg ttaaatcatg cgtgatgcga gctggttcat
     6841 agtatttttt ccaattgtct gcccagtctt cctcagctaa ttcttgactg tccacagtaa
     6901 cctgaccaac ctgtaaccca aaactagcta actccgctaa ctgttcatta atggtcgcaa
     6961 taacatccgc caaattagtg ctacttgggt aataggctgt gatagctatc atatcagact
     7021 gctccacatc tgggtataac tccccaaagc ggtccttttg cccaatatag tctgcgctat
     7081 ccgcgatagc gaccccttgg ctgcctgtct caatcaacac atgtgaaaca gcctcttgcg
     7141 catcacgatg cacatgaacc gtcacttctt gccacgtttc cataagtatg tcctttctat
     7201 tttgaccttt tggttattgt cctaatagtg ttagcaccat ctcgtgtgtc accttagtac
     7261 cttgggtaag ggtaacttgc tgcttcttct agtccttgtt gaccttcttc aaaagcttgc
     7321 gcgttccact ccaagaagaa atcagccttg ctgtcatctg ctaagaaatc catcaaatcg
     7381 ctgtgccctt caatagcaac atcgttgaga aattgcgcaa agtaagctaa gaattcacga
     7441 gaaaagccct ttttggcgtc aaaaggaata gtaaccaaat aatctgctgc atcaaattga
     7501 gacttggcag ggttgtaaaa gagcacatag tcctcaaaga caatgtcgtc ttgagtcact
     7561 tcgccactat cgtcaatggt ttttatggcc tctttatttt gagcttctaa aacaaaagtc
     7621 acttcaaccg catgattttt cttgtcccaa tccatagcat aatcatactg aaaatgctta
     7681 tccatttctt cttctaatac tgataaaaag ccgtattttg ccatcttttt tatacctaat
     7741 ctttctaact gttgctgcat aaggctttgt aagacctcat tagtttactt actttgacat
     7801 gctgagcgta ctgttataac ttttattaac tgaattataa catatttgac taatattgac
     7861 cataagagaa ggtcttaatg gctggatcac ttctagcaac cgcttttatg atataatttg
     7921 ggtatgcata gaaaaacgat tattgatttc aaagagctcg ggcaacgcta tctttttgat
     7981 gagccgttag tagaattggt agccaaaacc ttagatcagg tcggtccagt cattgaaaac
     8041 gtacaacact accaacagct gggctattac gtggtgggct atctcagtta tgaagcagct
     8101 gctttttttg acaatgcctt acaaacccat aatgacagac taggcaacga gtaccttgcc
     8161 tattttacag tgcacaaaac ctgtcaaaaa aaagacctac ctcttgatta tgacggcatt
     8221 actatcccta accaatgggt cagcgcaact caaaaaaaag cctatcaaaa agccattgaa
     8281 accattcacc gtgagatgca acagggcaac acttatcagg ttaactacac tattcaatta
     8341 actcaggaac tcaatgcagc tgacagctta gccatttaca ataaactcgt cgttgaacag
     8401 gctgctggct acaatgccta tatcgcccat gatgactttg ctgttatttc agctagtcct
     8461 gaattgttct ttaaacaaga gggcaacagg ttaactacta ggcctatgaa aggcaccact
     8521 aagcgcgggg ttaacacctg gttggatcag caggaacatg actggctcca agctgacggg
     8581 aaaaatcgct ctgaaaacat gatgattgtg gatttgctcc gcaatgacat ggggaaaatt
     8641 tgccaaacag gcagtgtttg tgtcgatagg ctctgtgagg tcgagcgata ctctaccgtc
     8701 tggcaaatga cctcaaccat tgttggtgac ctcaaagcga actgtgacct gatagacatt
     8761 ctcacagctc tctttccttg tggctctatc acaggggctc ctaaagtctc caccatggcg
     8821 attatcacat ctctggagcc aaacccaagg gggatttatt gtggaactgt tggcatttgc
     8881 ctacctgacg gtcgccgttt cttcaatgtt cccattagaa ccatccagct cagtcataat
     8941 caagctactt atggtgtcgg aggcggtatc acttggcaaa gcaagtggga agacgaatac
     9001 gaagaagtcc atcaaaaaac agcttttctc tatcggcaca aacaaatctt tgacctcaaa
     9061 acaaccgcca aggtggaaca caaaaaaata gccttccttg agcaacacct caatcgcctt
     9121 aaagaagcag ccacttattt tgcttaccct tataatgaaa aagctttgca gaaacaactg
     9181 tcaacctatt tggaaaataa ggataatgct gcctaccgct tgatgattcg tttatccaag
     9241 gatggaaaga ttagcctctc tgatcaaccc ttggaacctt tgtcagccga ttttctgaca
     9301 gctcaactct ctttacagaa aaaggacgtg acagcttcgc cttttaccta ctttaagacc
     9361 agctaccggc ctcatattga gcaaaaatct tatgaacagc tattctataa ccaagcgggg
     9421 caattattgg aaacgtccat tggcaatctt tttatccagc tgggtcagac cctctacaca
     9481 ccaccagtgg ctgtggggat tttaccagga ctttttcgcc aagagctgct agctactggt
     9541 caagctcagg aaaaagaggt gacactagct gatttaaaag aggctagcgc tatttttgga
     9601 ggaaatgctg tccgtggcct ctatcctctc aaccttgagc ttactcacct tgatgccctc
     9661 ttagctaaga gtcaagccta aactgccact catcttttgt tattaaggaa cctatgatac
     9721 tcttaattga taattacgat tcatttacct acaacctcgc ccaatattta agtgaatttg
     9781 acgagacgat tgtcttgtat aaccaagacc caaacttata tgacatggcc aaaaaggctg
     9841 acgctctagt cctctcacct ggtcctggtt ggcccaagga agccaaccaa atgccaaaac
     9901 tcattcaaga ctttttccaa acaaaaccta tcttaggagt gtgtctggga caccaagcga
     9961 ttgctgaaac attaggggga accttacgct tggccaaacg cgtcatgcat gggagacaaa
    10021 gcaccattga aacgcaaggc cctgctagtc tttttcgctc cctgccacaa gagatcaccg
    10081 tcatgcgcta ccattccatc gttgtggatc agttaccaaa aggttttagc gtaactgcta
    10141 gagactgtga cgatcaagaa atcatggcct ttgaacacca caccctgcca ctttttgggc
    10201 tacaatttca cccagaaagc atcggaactc ctgatggcat gaccatgatt gctaacttca
    10261 tcgcagctat tccccgttaa tcccatcccc caaaagaaag gaggacagtt acatgcctga
    10321 tcatttagcg ctcagaatgc gccccaaaac catttcagag gtcatcggac aaaaacacct
    10381 tgttggcgaa ggcaaaatca tccgtcgcat ggtggaagca aatagactat cgtccatgat
    10441 cctctatggc cctccaggaa tcggtaaaac ttccattgct tctgctattg ctggtactac
    10501 tagatatgcc tttcggacct ttaatgccac cattgacagc aaaaaacgtc tccaagaaat
    10561 tgcggaagaa gctaaatttt ctggtggctt ggtattatta ctagacgaga ttcatcgcct
    10621 tgacaagaca aaacaagatt ttcttttacc tttacttgag aatggcacca ttatcatgat
    10681 tggcgcaacc actgagaacc ccttcttttc agtgacaccc gctatcagaa gcagggtcca
    10741 gatttttgaa ttggaaccac tttctaacga ggatattaaa acagccattc agctagcaat
    10801 ttccgacaaa gaacggggat ttcctttttt agtgacaatt gatgatgagg cgctagattt
    10861 cattgttacc tccacaaatg gagacctacg atctgcttat aattccttgg atctagcagt
    10921 catgtctact tctcctaatg aagatggtag ccgtcatatt agtctagaga caatggaaaa
    10981 tagtctgcag cgtagttata ttaccatgga taaaaacggg gacgggcatt atgatgtttt
    11041 atctgcctta caaaaatcca ttagaggttc tgatgtcaat gctagcctgc actacgccgc
    11101 tcgtttagta gaagctggag acttgcctag tttagcaaga cgattgacca ttattgctta
    11161 cgaagatatt ggcttagcca accctgacgc ccaagttcat accgtcaccg cactagatgc
    11221 cgctcaacgc attggttttc cagaagctcg tattcttatc gctaacgtgg tcattgattt
    11281 ggctctatca cctaaatcca attcagctta tttagctatg gatgcagctt tagctgattt
    11341 gagaacatca ggtaacctcc ccattccaag gcatcttaga gacgggcatt atgctggcag
    11401 caaggaccta ggcaatgcca aagattacct ctacccacac gcctaccctg aaaaatgggt
    11461 caaacaacaa tacctaccag ataaattagt aggacatcat tattttgaag ccaatgaaac
    11521 cggtaaatac gaacgcgcac ttggttcaaa taaagagcgt attgataagc tctcagactg
    11581 actgctagtt ttaaaaatcg caaccgattt caaaaatcga taattttgct tgaaaaaatt
    11641 ttaaaaagtg gtattataaa agtacagaaa cattgctgtg gcatacgaat ccacatctaa
    11701 gtgttgaccg actatttctt tgtattttcg ggaaacaaag actctttcta gtctgcaagc
    11761 cgtttcacgc ggacgcaact tccaagaaag agcgcgttac ccacctgctt atactgcgcg
    11821 ggctcaatac aaaaacgtgg atcaccggtg ccaatacagc attcttgcct ccttagctca
    11881 gttggtagag cagtagactc ttaatctatg ggtcacaggt tcgagccctg tagggggtat
    11941 aaactataca taaaaaagcc tttgtttaaa ggcttttttg cttgtttcat aactaatcgg
    12001 cttaattaaa agcgtcaatc cacttttagt atcatgtctc aattttcatt tgatagtcag
    12061 caagtatatc tacaaaattg ttaatgatta tttcttttga aagtgttata ttaaaacata
    12121 ataaaataat aactcctgaa aagaggctat ttatgaaaaa aacaaaactt attttttctt
    12181 ttacttcaat attcattgca ataatttctc gtcctgtgtt tggattagaa gtagataata
    12241 attcccttct aaggaatatc tatagtacga ttgtatatga atattcagat acagtaattg
    12301 attttaaaac cagtcataac ttagtgacta agaaacttga tgttagagat gctagagatt
    12361 tttttattaa ctccgaaatg gatgaatatg cagccaatga ttttaaagat ggagataaaa
    12421 tagctatgtt ctccgtccca tttgattgga actacttgtc agaaggaaca gtcatagcat
    12481 atacctatgg tggaatgacg ccttatcaag aagaaccaat atctaaaaat atccctgtta
    12541 atttatggat taatggaaag cagatctctg ttccttacaa cgaaatatca actaacaaaa
    12601 caacagttac agctcaagaa attgatctaa aggttagaaa a
//
LOCUS       DAUGSW010000036        12534 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUGSW010000036 DAUGSW010000000
VERSION     DAUGSW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12534
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.036"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            42..563
                     /locus_tag="VIB18_001340"
     CDS             42..563
                     /locus_tag="VIB18_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8766343.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            778..1296
                     /gene="rimM"
                     /locus_tag="VIB18_001341"
     CDS             778..1296
                     /gene="rimM"
                     /locus_tag="VIB18_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEQ8766344.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DQFVQEVTIVSHRKQKNFDIIKFKDMYHINAIEKYKDYTLKVSKANQGDLQEGEFYYH
                     QIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLSVDVPNKRV
                     DVELMEGLDDED"
     gene            1286..2017
                     /gene="trmD"
                     /locus_tag="VIB18_001342"
     CDS             1286..2017
                     /gene="trmD"
                     /locus_tag="VIB18_001342"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEQ8766345.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALGQGED"
     gene            2017..3009
                     /locus_tag="VIB18_001343"
     CDS             2017..3009
                     /locus_tag="VIB18_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8766346.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            3187..4245
                     /locus_tag="VIB18_001344"
     CDS             3187..4245
                     /locus_tag="VIB18_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEQ8766347.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNRFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            4258..5181
                     /locus_tag="VIB18_001345"
     CDS             4258..5181
                     /locus_tag="VIB18_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEQ8766348.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     IVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
                     ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            5437..6150
                     /locus_tag="VIB18_001346"
     CDS             5437..6150
                     /locus_tag="VIB18_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8766349.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            6147..7058
                     /gene="pfkB"
                     /locus_tag="VIB18_001347"
     CDS             6147..7058
                     /gene="pfkB"
                     /locus_tag="VIB18_001347"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEQ8766350.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISQEQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            7055..9001
                     /locus_tag="VIB18_001348"
     CDS             7055..9001
                     /locus_tag="VIB18_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8766351.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEVAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            9094..9693
                     /locus_tag="VIB18_001349"
     CDS             9094..9693
                     /locus_tag="VIB18_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8766352.1"
                     /translation="MKVKKRRRRARSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            9846..10553
                     /locus_tag="VIB18_001350"
     CDS             9846..10553
                     /locus_tag="VIB18_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8766353.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(10610..10927)
                     /locus_tag="VIB18_001351"
                     /pseudo
     CDS             complement(10610..10927)
                     /locus_tag="VIB18_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(11125..11469)
                     /locus_tag="VIB18_001352"
     CDS             complement(11125..11469)
                     /locus_tag="VIB18_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766354.1"
                     /translation="MLRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFDFKIRKF
                     LMESKEIHLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVLKKYKDNKTINMK
                     DFSYFDIYLWTK"
     gene            complement(11510..>12534)
                     /locus_tag="VIB18_001353"
     CDS             complement(11510..>12534)
                     /locus_tag="VIB18_001353"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEQ8766355.1"
                     /translation="RKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIIYSEVTP
                     YHVTSVWTKGVIPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNML
                     HWWLDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAF
                     PGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQ
                     SKLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNG
                     NLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQD
                     SWNQTN"
BASE COUNT         3835 a         2088 c         2604 g         4007 t
ORIGIN      
        1 gcacctgttc aatagtgaac aacatttaga aagtgtccga tatgacaaaa gacagacaaa
       61 tcaaaaaaac aaaaacagct atctatagtg cttttattgc tttattacaa aaaaaagaat
      121 attcgaaaat aactgttcga gatatgatta cacttgctaa tgtagggaga tcaacctttt
      181 atgcacatta tgaaagcaaa gaaatgttac taaaagaact ctgtgaagaa ctttttcatc
      241 atttgtttag gcaaaaaaga aatgtgactt ttgaagacta tttggtacat attttaaagc
      301 attttgaaca aaataaagac agcattgcga cgttgttact ttctaatgat ccctattttt
      361 tattaagatt taaaaacgaa ctagaacatg atgtttaccc taacttgcgc tgcaagtata
      421 tcgacaaaac gactattcca gaagtattcc tgaaacaatt tgttctatct agttttatag
      481 aaaccttaaa atggtggctc catcaaaggc aaaggatgtc tgcaaatgaa ctattaaagt
      541 attatttaga gctcataaaa taatgactag tgagtcatct tgccaaattc aattttttaa
      601 tacagacgga ttttaacaat ttaacagaga aagacaaaac tgtaagtgca aaatagacta
      661 taacgtgata aaataatagg taatttggtt ctgaaaaaga agtgtctatc aaactttaga
      721 atcaagagag gtcgctaaag tgacgtgaga taaagagtta acgatttagg agctaccatg
      781 gaatatttta atgttggaaa aattgtcaac acgcaaggcc tgcaaggaga gatgcgcgtg
      841 ttgtctgtca gtgattttgc tgaggagcgc tttaagaagg gatcgcaatt ggctttgttt
      901 gatgacaaag accagtttgt tcaagaggtc acgattgtta gccatagaaa gcaaaaaaac
      961 tttgatatca tcaaatttaa agacatgtat catattaatg cgattgaaaa atataaggac
     1021 tatacgttaa aagtgtcaaa agctaatcaa ggagacctgc aagaaggaga attttactac
     1081 catcagatta tcggtatggc tgtttatgaa aaggaccggt tgattggcta tgtcaaggaa
     1141 atcttgcagc caggtgctaa tgatgtttgg gtagtgaaac gccaaggaaa acgagacttg
     1201 ctcttaccat atattccccc agtagttctt agcgtagatg ttcctaacaa gcgcgtagat
     1261 gttgaattga tggaaggctt agacgatgaa gattgatatt ttaacccttt ttcctgaaat
     1321 gtttgccccc ctagaacatt ccattgtagg caaagcaaaa gaaaaaggat tacttgacat
     1381 tcactaccat aactttcgag attatgctga aaaagctcgt catgtggatg acgaacccta
     1441 tggtgggggc caaggcatgt tattgagagc gcagcccatt tttgacacca ttgaacagat
     1501 tgaagccaaa aaaccaagga ttattctttt agatccagca ggtaaaccct ttactcaggc
     1561 ttatgctgaa gaattagctc ttgaggaaga gttaattttt atttgtggtc attatgaagg
     1621 ttatgatgag cggattaaga ccttggtgac ggatgaaatt tcattaggtg actttgtatt
     1681 aacaggaggt gagttggcgg ccatgactat agtggatgcg accgtcaggt taattccaca
     1741 ggtacttggg aaagaaagta gccatcagga cgattctttt tcatcaggac ttttagaata
     1801 ccctcaatac acaagacctt atgattatcg tggtatgaca gttccagatg ttctaatgag
     1861 tggtcatcac gaacgtattc gcttgtggcg tctagaagaa agtctcagaa aaacctattt
     1921 gagaaggcca gatttgttag agcggtacga tttttccgag gaagagcgca agctattgga
     1981 taagattaaa gaagcattgg gtcaaggaga agattagtga aagataaagc atatgatatt
     2041 acgattattg gtggtggtcc aataggttta tttgcagcct tttatgcagg tcttaggggc
     2101 gtaacagtaa agattattga gagtttgtca gaacttggtg gacagcctgc cattctttat
     2161 cctgagaaaa tgatttatga tattccagct tatccatctt taacaggtgt tgagttgaca
     2221 gaaaatttaa taaaacaatt gagccgtttt gaagatcgta caaccatttg tttaaaagaa
     2281 gaagtattaa cctttgacaa ggttaaaggt ggtttttcga ttaggactaa taaggcagag
     2341 catttttcaa aagccattat cattgcttgt ggaaatggcg cttttgcacc aagaacttta
     2401 gggttagaaa gtgaggaaaa ctttgctgat cataaccttt tttataatgt tcaccagttg
     2461 gaccagtttg cgggacaaaa agttgtgatt tgtggtggtg gagattcagc agttgattgg
     2521 gctttggctt tagaagatat tgctgagagt gtgacggttg tgcaccgtcg tgatgctttc
     2581 agagcacatg aacacagtgt ggaattattg aaagcatcaa cggtcaacct cttaacacct
     2641 tatgtgccaa aagcattgaa aggaattgga aacctggctg aaaaattagt tattcaaaaa
     2701 gtgaaagaag atgaagtgtt agaacttgaa ttggacagtc ttattgttag ttttggtttt
     2761 tcaacttcta ataagaattt gaaaaattgg aatctcgact ataagcgttc aagtattact
     2821 gtttcaccac tttttcaaac aagtcaagaa ggtatttttg ccattggtga tgcagccgct
     2881 tataatggga aagtggattt gattgctact ggttttggcg aagcaccaac agcagttaat
     2941 caggccatta actatattta tccagatcga gataaccgtg tggtgcattc aacctcttta
     3001 attgactaag ggagtcggaa gtttcaagag cagtagcaac agctaatatt cagtttgtca
     3061 ggagaggaca aatggttttt acctaagtct tcgtgacaag ttttatactt tgtgataaaa
     3121 tagtcattgt gaaaaaagtg tgatggtttt cacagattaa cacattacaa tgaaaagggg
     3181 tctatcatga caacaacaga taaagagaca tttagttctt ttatgaataa ggtcttggct
     3241 ggtacagcga ttgctatcgt tgtggcactc attccaaatg ctattttagc gactttctta
     3301 aaaccgcttt tgccaaacat ggcagctgct gaatttttac acattgtgca agtcttccaa
     3361 ttcttcacgc cgattatggc tggtttcttg attgggcaac aatttaagtt taatcctatg
     3421 caacagttgg ctgttggtgg agctgcttat atcggttctg gggcttgggc ttatacagaa
     3481 gtcattcaaa aaggtgtggc gacaggaaca ttccaactta gaggtattgg ggacttaatc
     3541 aatatgatga ttacagctag ccttgcggtt ttagctgtga aatattttgg gaatagattt
     3601 ggctctttaa ccattatctt gttacctatc actataggaa ctggcgtagg ttatattggt
     3661 tggaaatttt tgccttatgt gtcttacgtg acaaccctga tcggacaagg gattaattct
     3721 tttacaacct tacaacctat tttaatgtct attttaattg cagttgcttt ctcgcttatc
     3781 attgttagtc cgatttcaac tgttgcaatc ggtttagcta ttgggcttaa tggaatggct
     3841 gcgggagcag cttctatggg aattgcatcg acagcagcag tcttagtgtg ggcgacgctt
     3901 aaagttaata aatctggtgt accaattgct atcgcacttg gggctatgaa aatgatgatg
     3961 ccaaacttct tgaaacatcc tatcatggct attccgatgg tgttcactgc agcaattagc
     4021 tcattaacag taccattgtt taatcttgtt ggaacaccag cttcatctgg ttttggctta
     4081 gttggtgcag taggtccgat tgcttcttta gcaggtggta gctcaatact tattattatc
     4141 cttgcttgga tcattgttcc gtttgcggtt gcttttgcgg cgcataaggt ttctaaagat
     4201 attctaaaac tttataaaga agacattttc gtctttgaag gctaatagga ggaaaatatg
     4261 ttagtttata ttgctggctc aggagccatg gggtgccgtt ttggttacca aatttcaaaa
     4321 acaaataacg atgtgatttt gttagataac tgggaagatc atatcaatgc cattaaagaa
     4381 aacgggttga ttgtaacagg tgatgtggaa gaaacagtta agcttcctat tatgaaaccg
     4441 actgaagcca ctcaagaagc cgatttgatt atcttgttta caaaagcaat gcagttgcca
     4501 caaatgcttc aagacattaa aggcattatt ggaaaagaaa ccaaagtgct ttgcctttta
     4561 aatggtcttg gacacgaaga cgttattcgt cagtacattc cagagcacaa cattttgatg
     4621 ggggtcactg tctggactgc tggtctagaa ggaccaggtc gtgctcatct tcaaggagtt
     4681 ggtgctctta acttacaaag tatggatcca aacaatcaag atgcgggaca tcaagtggct
     4741 gacttgctaa ataaagctaa cttaaatgcg acttatgatg agaatgttgt gccaaacatc
     4801 tggcgaaaag cttgcgtgaa tggtaccatg aactcaactt gtgctctttt agattgtacg
     4861 attggcgaat tatttgccag tgaagacggt ctcaaaatgg taaaagaaat catccatgag
     4921 tttgttatcg ttggtcaagc agaaggtgtc gaactaaacg aagaagaaat cacacaatat
     4981 gtaatggata catctgttaa agctgctcac cattacccat caatgcacca agaccttgtg
     5041 caaaatcacc gattgactga aattgatttt atcaatggtg cagtcaatac caaaggtgaa
     5101 aagcttggta tcaatactcc atactgccgt atgattacag agctagttca cgctaaagaa
     5161 gcagtgttga acatccaata aacgctatca aatcgttata ctcaatatta tggctaaagc
     5221 tttaatattg agttttttgt tatgctgata gtatttttct taggcgtcat tatttgtgag
     5281 cctagattat gagttaataa aagaaataat aattggtaga atttgataga ttttgaaagg
     5341 ttatgcttga cttttagtta taaaatagta taataattgt aaacgatttc agttaggggt
     5401 ggttctatct taaaatcaaa acgaaaacaa ttaatcatgg caaagatcac tgaagaaaac
     5461 tatgtttctt tagaggattt aatgcaatta ctcaactcct ctgagtctac tatccgtaga
     5521 gatctaggag agttggagca agaaggacgg ctacatcgtg ttcatggagg tgctgaactt
     5581 tttcactctt tacaagagga actttctaac caagaaaagt ctgtcaaaaa cagtcatatt
     5641 aaaaaagcta ttgcgcaaag agcctctcag cttatctatg acaacgatgt gatctttatt
     5701 gatgctggga caacgactga atttttatta ccttttttac aagctaaaaa tttaactgta
     5761 gttactaatt ctattcatca tgctgctaga ttagttgaac tctctattga gacgattatt
     5821 gtaggtggtt atgtcaaaca aacgaccgat gccagtattg gtaatgtagc tttggaacag
     5881 attaggcaga tgaattttga caaggcattt cttggaatga atggtgttga tgattcttac
     5941 ctgacgactc ctgatatgga agaagcagtt attaaaaaag cggttctgtc aaatgcaaaa
     6001 ttagcttaca ttttagtaga tggcactaaa attggtcagg tatcgtttgt aaaagtagct
     6061 cctattaatg atgtgactat tattacatta ggaggatcag caagtattct taaacaaata
     6121 aaggaaaagg caaaggtgat tgaattatga tttataccgt gaccttaaac ccttctattg
     6181 actttattgt cagaattgac caaataaatc ttgggtcagt gaatcgcatg gcgagtgatg
     6241 ataagtttgc tggaggtaaa ggcattaatg tgagtcgtat cttgcaacgt ttagacattg
     6301 ctagcacggc gacagggttc ttgggtggtt ttacaggacg ttttatcgaa gaaagtttga
     6361 gtgcagaagg cgttaaaact gattttgtaa aaggtgatca agatactcga atcaatgtta
     6421 aaatcaagtc acaagaagag accgaattaa atggtcaagg acctatcatt agtcaggaac
     6481 aactggagga tttgaaaact aagctttccc agctaacagc agaggataca gttgtctttg
     6541 caggttcagc gccagctaat cttggcaatg ctgtttataa ggaattactt cctttagtta
     6601 ggcaaagcgg tgctcaggtg gtttgtgatt ttgaaggtca gactttaata gatgcgcttg
     6661 catataatcc tctgttggtt aaacctaata atcatgaact agaagctatt tttggtacga
     6721 ttctgactag tcttgatgat gttgaaacct atgcccgtcg tcttttagag atgggtgctc
     6781 aaaacgtcat catttcaatg gctggtgatg gtgctttgct ggttactaaa gaagcgactt
     6841 attttgctaa accgattaag ggagaagtta aaaattctgt cggtgctggt gattcgatgg
     6901 ttgctggctt tacaggcgaa tttatgaaga gtcaaaatcc aatagaagcc ttaaaatggg
     6961 gcgtggcttg tggtacagcg acggctttct ctgatgactt ggcgacaatt gcatttatta
     7021 aggaaacata tcataaagtt gaggtagaaa aacgatgaaa attcaagatt tattgagaaa
     7081 agatattatg attctcgatt tacaggctat ttctaaagaa gttgccattg acgagatgat
     7141 tactaaatta gttgaaaaag atattgtaca tgattttgat gtctttaaaa agagtatcat
     7201 gacacgtgaa gaacaaacat caacagggct tggtgatggg attgccatgc ctcattctaa
     7261 aaatattgta gtagataaac cagcggtctt gtttgcgaaa tcaaataaag gtgtggatta
     7321 taaggcttta gatggtcaac caacggatct cttctttatg attgctgcgc ctcaaggagc
     7381 aaatgatact cacttggctg cgctagcaga attatcacaa taccttttga aagacggctt
     7441 tgctgataaa cttcgtgctg cagcgacacc agaagcagtc attgctgttt ttgatgaagc
     7501 gtcaacagct aaagaagaag tggttgctcc aacaagtggt caagacttta tcgttgctgt
     7561 tacagcttgt ccgacaggaa ttgctcacac ttatatggca gaagaggctt tgaaaaaaca
     7621 agctgcagaa atgggagtag ctattaaagt tgaaacaaac ggtgcttctg gtgtggctaa
     7681 tcgtttaacc gctgaagata ttcagagagc taaaggagtt attgttgcag ctgataaagc
     7741 ggttgaaatg gaccgttttg atggtaaaca attcattgct cgccctgttg cagatggtat
     7801 caagaaaagt caggaattga tttctttgat tttaaacaat gaaggaaaca cttatcatgc
     7861 taaaaatgga aaatctgaaa cagcagtatc aactgagaaa acaagtttag gcggtgcttt
     7921 ctataaacac ttgatgggcg gtgtctcaca aatgttgcca tttgttattg gtggcgggat
     7981 tatgattgct ctagcatttt tattggataa catgcttggt gtgccaaatg atcagcttgg
     8041 aagtcttgga tcctatcatg aagtagcagc tatttttatg aacattggtg gagcagcctt
     8101 ttccttcatg ttaccagtac tagcaggtta tatcgcttat tctattgctg aaaaaccggg
     8161 cttagtagct ggttttgtgg caggtgccat tgcctcaaat ggtcttgctt ttggtaaggt
     8221 accatttgca gcaggaggag aagtgagctt gggcttaacg ggcgtgccat caggtttcct
     8281 tggggcgctt gtgggtggtt tccttgccgg tggtgttatt cttgcccttc gtaaattgtt
     8341 ggcaggccta ccacgttctc tagaaggggt taaatctatc ctcctttacc cattacttgg
     8401 cgtccttgtc actggtttct tgatgctttt tgtcaatatt ccaatggcag ctattaatac
     8461 agcccttaat gatttcttac aaggtctttc aggaagctct gctgtcctta tgggacttct
     8521 tgttggtgga atgatggctg ttgacatggg tggtcctgtt aataaggcag cttatgtttt
     8581 tggtacagga actttagcag ctactgtggc aaatggtggt tcggtcgtta tggccgctgt
     8641 tatggcaggt ggtatggtac ctcctcttgc tgtttttgta gccactctct tgtttaaaga
     8701 taaatttacc aaagaagaac gtgaatcagg cttgacaaat attgttatgg gactttcatt
     8761 catcaccgaa ggagcaattc cgtttggtgc agctgaccca gcacgtgcga ttcctagctt
     8821 tatcgcaggt tctgccttga caggagctct tgttggtttg gctggtatta aattaatggc
     8881 gccacatggt ggtatcttcg taatcgcttt aacaagcaat ccaatcttat atcttgtctt
     8941 tgttgtgatt ggcgcccttg tatcaggtat cttatttggc gctcttcgca aaaaagccta
     9001 aaaggtaaag aacttttttc ttactaaaac tagaatctgt caaggttcta gttttttgct
     9061 atactagagt taaaggataa gaaacgagga cctttgaagg tgaaaaaaag gagaagaagg
     9121 gctagatcat cagtaaatcg acttgtctta gggttagtat tacttaatct gattgttagt
     9181 atgtggacac taaaattggg aaaccagcga ttagctccgt atgcggatca cgaaactctg
     9241 acatttgtca ggaagattag tcatgctgct caatcagtcg ctcaaaagaa acagttatac
     9301 agttcggtga tgatggctca ggccatttta gaatccaata atggcaagtc acaactaagt
     9361 caaaaacctt attataattt tttcgggatt aaggggagct ataaagaacg gtcagtcatt
     9421 tttccaactt tagaagacga tggacaaggg aatctttatc aaattgatgc tgcttttcgt
     9481 tcctatggga gcctgacagc ttgtttttta gattacgcaa gagttttgaa tgatccactt
     9541 tatgacaaaa cccacaaaaa gttttggtct cattatcaag atgctactgc aaccttaaca
     9601 ggcacttacg ccactgatac aacttaccat accaaattaa atgaattgat tgaatggtat
     9661 caactcacta attttgatgg tctaatgaaa tagttatcca caattttaaa aaaaatcaga
     9721 agaaatatgt cgatttcaag acaaaagtta tcaatctcat taaattatct gtggaaaagt
     9781 taatttaaac gttcgtgtgc tataatagaa acatagaaaa tgtaataaaa aaggatatgt
     9841 gaataatgac aaaaaagaaa ggtaagcttg tacttatcag tctttttgtt ctagcagctt
     9901 gtttaggagc ttatagtgca atgagacaat ctcataaaac ttcaaacgtg tcagctgaga
     9961 ctatcgccag ttcttcaacc cgacatttta ttgatgaaat tggtccaact gctagtacta
    10021 ttggtcaaga acgtgatctt tatgcgtctg ttatgatagc acaagcgatt ttagaatcaa
    10081 gtaatggtaa atcaagtcta agtcaagcac cttattataa ttttttcggt attaagggtg
    10141 cctataacgg ttcttctgtg acgatgtcaa cttgggaaga tgatggtaat ggcaatacct
    10201 atacgattga tcaagccttt agagcttatc caagtattgc agactccctt aatgactatg
    10261 cagacttgct aagttctagc acttatatag gtgctagaaa atcaaacacg ctatcgtatc
    10321 aagatgctac agcagctcta actggcttat acgctacaga caccagttat aacttaaaac
    10381 taaataatat tattgcaacc tatggtttga cggcttatga tgttgctaat agctcagctc
    10441 aagaaactgg tctagcaact tcgggttatg tttggaatga gtatcgtcgt aattacactg
    10501 atgcggagac cctagcagtt gatgaggctt gggctaaacg catgacttat taatgtaaca
    10561 ctaacaacaa tctgcttgca ctgaccccaa aaaagctgga tactctattt taagtaaagg
    10621 atttagttct gtattgtaca gaactaaatc cttttagttt tactttgata tgtttatcgt
    10681 tgtaataatc aatgtcattt gtaatcgctt attctaagtc ttctagtgat ttatagttat
    10741 tctcataacc atagaacatt tctgacttta agatgccaaa gaaagattcc atcatgccat
    10801 tgtcaggact gtttctttta cgtgacatag acggacgaat tcctttagag tttaggaaat
    10861 gatgataata gttgtgttga tattgccaac cttgatcact ctattatata gttccgtcat
    10921 agcatttatt tggagatgcc tttttccatt attggtttaa tgtgatttaa gcaaggttat
    10981 tagctaaact taatgccaga caaaaacacc ccaattatta gattttttgt ctaacttttg
    11041 gggcgcaatt caatctgagc agttttagat ttggtatcaa tgttattata ggtcaattga
    11101 tcatatttat ccaaagcttt tagcttattt agtccaaaga taaatatcaa aatagctgaa
    11161 atctttcatg tttatagtct tattgtcttt atattttttt aagacatcag atctggtgct
    11221 attgggtttt gcgtcatata aattgatttt ttcatgtttc ctatttttac tgtgaatttc
    11281 taaactcccc cttatataag gagacttagt caaatgaatt tcttttgatt ccatcaaaaa
    11341 ttttcttatt ttaaaatcga actcttgaat cgtaacaata tccttatcga tttttatagg
    11401 atttattaat gttttttgct gttgcccatc tataaaaaaa ttccctgcaa tagtattagt
    11461 ccttagaata ccatcatctg ttgaatgtaa tctttcttat tgatacgctt taattggtct
    11521 gattccaact atcttgccct gttgaaagtg taaataaccc tagtacttga gcaccaatat
    11581 tatcttcttt tatttcttta gcagaaatag ctacttttcc agcggaatta acaccaacaa
    11641 agtatttctt cataccaata gatgcattac tatcagagtc tgttacataa atagctttaa
    11701 ggttcccgtt agaatcaaag tcagctcccc acaggtttat aacatggttg atgcgtacgt
    11761 tagcgtaggt gtgtgatagg cctagagcct tgccttcggt taactctttc ttaatgagat
    11821 cactgatttc tttgagattt ttttctttaa aatcatgacg acttgtcaat agcttacttt
    11881 gatcacctct tgtaaatacg gcgtcaaaaa taccacctcg gcgatctttc tcttgatagg
    11941 ttctattgac atcagtagtc tgtgtcttat aaacatttaa gtaataacca ttgataaaca
    12001 tatctaaaac aagatcaggc ataactccaa ttcggcgtgc tgacaaaccg gggaaagctt
    12061 tatctcggaa ataattaaaa agctcgctat ttgtttggtc acctttagta ttaataactt
    12121 ttcttacatc caataattct tgatcaccaa acatgatttt ttgtttatct gggtgttttt
    12181 ttagatatgc ttcaattttt tcgttgtttt gatctaacca ccagtgaagc atattccctg
    12241 ctgtggcagc cccgcaaaga aggtcgtctt ttccattgaa tgttttggta atatcatacc
    12301 atccttggtt agcaacataa ggagcgtgaa aaacatcttc gccttgagtg aattttgctg
    12361 gaggaataac tcctttggtc caaacggaag taacgtgata aggtgttact tccgaatata
    12421 taatctcttg attagcagaa aaactatctg ctataacacc acgatctacc gatagagcaa
    12481 ataaagtcac tgctgccaat actgcagctg aagttgaata gcatcttttt ctca
//
LOCUS       DAUGSW010000037        12145 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUGSW010000037 DAUGSW010000000
VERSION     DAUGSW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12145
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.037"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(113..418)
                     /locus_tag="VIB18_001354"
     CDS             complement(113..418)
                     /locus_tag="VIB18_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEQ8766356.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            complement(430..849)
                     /gene="ruvX"
                     /locus_tag="VIB18_001355"
     CDS             complement(430..849)
                     /gene="ruvX"
                     /locus_tag="VIB18_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEQ8766357.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            complement(846..1115)
                     /locus_tag="VIB18_001356"
     CDS             complement(846..1115)
                     /locus_tag="VIB18_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEQ8766358.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            complement(1229..1627)
                     /gene="spx"
                     /locus_tag="VIB18_001357"
     CDS             complement(1229..1627)
                     /gene="spx"
                     /locus_tag="VIB18_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEQ8766359.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            complement(1918..3054)
                     /gene="recA"
                     /locus_tag="VIB18_001358"
     CDS             complement(1918..3054)
                     /gene="recA"
                     /locus_tag="VIB18_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEQ8766360.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            complement(3143..4414)
                     /locus_tag="VIB18_001359"
     CDS             complement(3143..4414)
                     /locus_tag="VIB18_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEQ8766361.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDKQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            complement(4483..5043)
                     /locus_tag="VIB18_001360"
     CDS             complement(4483..5043)
                     /locus_tag="VIB18_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEQ8766362.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFESLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADALENPSIIRHKLKLAATVNNAIA
                     VQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            complement(5053..5649)
                     /gene="ruvA"
                     /locus_tag="VIB18_001361"
     CDS             complement(5053..5649)
                     /gene="ruvA"
                     /locus_tag="VIB18_001361"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEQ8766363.1"
                     /translation="MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
                     LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            complement(5651..6871)
                     /locus_tag="VIB18_001362"
     CDS             complement(5651..6871)
                     /locus_tag="VIB18_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8766364.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLASFQNYRQVFHDRA
                     FVFFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRANMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            complement(6882..8864)
                     /gene="mutL"
                     /locus_tag="VIB18_001363"
     CDS             complement(6882..8864)
                     /gene="mutL"
                     /locus_tag="VIB18_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEQ8766365.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGVFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            complement(8959..10110)
                     /locus_tag="VIB18_001364"
     CDS             complement(8959..10110)
                     /locus_tag="VIB18_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8766366.1"
                     /translation="MIMKITEHKKKNGTIVYRASIYLGIDQMTGKRVKTSITGRTRKE
                     VNQKAKHAQLDFLSNGSTIKRKVVIKTFKELSHLWLETYKLTVKPQTYDATVTRLNRH
                     IMPTLGNMKVDKITASDIQMLINRLSKYYVNYTAVRSVIRKVLQQGVLLGLIDYNSAR
                     DIILPRKQPNAKKKVKFIDLSDLKSFLEHLETSQHKRYNLYFDAVLYQLLLSTGLRIG
                     EACALEWGDIDLENGTIAINKTYNKNLKFLSTAKTQSGNRVISVDKKTLRSLKLYQMR
                     QRQLFNEVGARVSEVVFATPTRKYFNASVRQSVLDTRCKEAGIERFTFHAFRHTHASL
                     LLNAGISYKELQYRLGHANISMTLDTYGHLSKDKEKEAVLYYEKAMNNL"
     gene            10380..10523
                     /locus_tag="VIB18_001365"
     CDS             10380..10523
                     /locus_tag="VIB18_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEQ8766367.1"
                     /translation="MSRGDAYVCKSQKPKERRRQGLSVYETLTLMIAFGTLIVAIMNN
                     KNK"
     gene            complement(11384..12064)
                     /locus_tag="VIB18_001366"
     CDS             complement(11384..12064)
                     /locus_tag="VIB18_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8766368.1"
                     /translation="MIKTNFAVLMAERGLKIADVYEDTGISKTTLMALSENTGKGVQF
                     DTVDKLCNYLGIELKDFFVYSPYIWKAYNKEDYEYKEEGDNLIAINLKSTHSERVYIL
                     KLFFFSPKHIDSPTDDTTVKLWVRLSLDEDSGNYGYNEFYDFISSLPISFQTHFYNDV
                     IEVLKKHYLNSGAVISAYRYDFHPDKEYLSEIVLNKNDKVIVSFFDSYGNSHAPKAIQ
                     IDKLIKVD"
BASE COUNT         3740 a         2508 c         2042 g         3855 t
ORIGIN      
        1 ataaatttat catttaattc ttttatcatt atcacctcct gcttatttat tcgaaaataa
       61 cattaaaaaa atagccctca cggctacttt ttaacatagt gtcactaaca atttagttct
      121 catctagaaa actattaaat acctcttcaa tcatatccca ttcagcatct gaatcctcag
      181 gaatcggttg taaatcccct tcagtaccat cttcattttc agtaaatgaa taggcttgga
      241 tttcaatttc accagactca tcttcttcag atcccgctgg aaccaagaga acataatttt
      301 taccaaactc ttcacgaccg tcaattgtta ataaaatttc aaacaaggtt tcatttcctt
      361 gttcatccac aagtgtgata acttcgtgtt ggtggtcatt ttcatgatta tgtgtcattt
      421 tttatctcct taaaaattcc gatttaaata gttctgtaaa atgagttgtg cagctaattt
      481 atcaatgact ttttttcgct taccacgact aatgtcagct tgctcaataa gcatacgctc
      541 tgcctcaaca gtcgtcaatc gttcatcttg ataatggact ggaagtccaa agaggtgctc
      601 tatgtggttt ccataagtta tacttgcatc aacacgtgga ccattggtgt tattcatatt
      661 ttttggcaat ccaataacaa actgttcaac ttggtactgc ttaacaagct cttctaaacg
      721 tgtaaagcca aattctgctt tttcctcatc aatcttgata atttcaagtc cttgggctgt
      781 aaagccaaga ggatcactaa tagctacacc aaccgttttc gagccaacat caagtcccat
      841 tattctcatt taacatcaat tccatttcct tgtaaatagt agcgaacaag ttcttctaca
      901 atttcatcac gttcatattt acgaatctga tttcgagcat cattataacg aggaacataa
      961 gctgggtccc cactcaagac ataaccaaca atttgattaa ttggattata acccttttca
     1021 tcaagtgaat gatagactgc tgttaatgtt tcactaattt gtcgtttgtc gccatcatcc
     1081 aacttaaagc ggactgtttc atctgtaaat cccatactta caccttcttt ctaaaattaa
     1141 gtgctatgct ttattatagc ttatttctat taaataaaca agaatttcaa gcgaagaagg
     1201 tatttaaaaa aaagctctac aagagctttt agagtgcagc acgtaatcgt gcttcagtat
     1261 tttcaatatt acgaatagag cgaggtaaaa aagcacgaat atcgtcttct ttgtagccta
     1321 cttgcagacg tttatcatca atcaaaatgg gacttttaag gatgcgcggg ttatcttgaa
     1381 tcaaatcaat aacctcacta acacttaatt cttcaatatc gcaatcgaga gctttggcat
     1441 aacgattttt agatgaaaca atgctctcca ctccattttc ggtttttgat aaaattgcta
     1501 aaatttcttc tttagttagc ggttcttttc ctaagttctg ttctttataa gcaagcttat
     1561 gggcatttag ccaagttttg gctttcttgc agctcgtaca acttgaaatc gtgtaaattt
     1621 taatcatgtt gctgactcac tttctatttc gtgatagctt tattgtagca cagtttctta
     1681 tctataaata taggtctttg gacctatttt tttaatttta aagatattat cttggtaaaa
     1741 taaggttttt cacctgtatt ctcttgaatt attagttatt ttaattttat atcagttaac
     1801 ctaagttctg ctctctcaca tctttttaaa tgatggtttc tattcaccca cacacctatg
     1861 aacagtagtc ctactaacct ttaaaaatac attttaaaaa gccctgaagg gctcttttta
     1921 atcttcaatt tcaataccat tatctaaatc taaagcaaga tcatcggttt cttctgatgc
     1981 tactgccata gcagattctt cttcactttc ttcaagcaaa ccaaatttaa cacgtacttt
     2041 acggtcgatt tcatcaaaca attgtggatg atcggccaaa taacgcttag cattttcaga
     2101 accttggcca atcttctcac cattataaga gaaccaagca cctgcttttt ggataatgtc
     2161 caaatcagaa gcaattttca caagctcccc tgtacgagaa ataccttccc catacatgat
     2221 ttcaacttct gctaccttaa atggcggagc gaccttgttt ttaacaacct tgattttggt
     2281 ctccttacca atgctgctat ctttttggtc accagttcct ttaatttgag ttgttccacg
     2341 cacatccagc cgaacagaag cataaaattt caaagctcga ccacctggtg ttgtttcagg
     2401 atttccaaac atcacaccaa ctttttcacg caattggtta ataaagatag cgatagtttt
     2461 tgttttatta atagaagctg ataatttacg catggcctga ctcatcatac gtgcttgcaa
     2521 tccgacatgg ctatcgccaa tatcaccatc aatttcagca cgtggcacta aagctgctac
     2581 tgaatcgaca acaaccagat caaccgcacc agaatcaatc aatttacctg caatttcaag
     2641 tccttgttct ccagaatctg gttgagacaa gaggagttca tcaatattaa ccccaagcgc
     2701 agcagcataa gctggatcaa gcgcatgctc ggcatcgata aaggctgcga ttccaccttc
     2761 tttttgagct tgtgctacag catgtaaagc cacagtcgtt ttaccggaag actctggacc
     2821 atagatttcg atgatacgtc ctttaggata accaccagct ccaagcgcaa tatcaagagc
     2881 tagacttcct gaactcataa cctgaacttt ttgctctgca cgttctccta atcgcatcac
     2941 tgcgccctta ccaaaatctt tttcaatatt tttcaaagca tcatcaaggg ctttgcgacg
     3001 ttcgtcacca aacttcttag tgatttcttc attctttttt aatttttttg ccaatacttt
     3061 ctcctctttt ttaacaaacc atcgtcagca ggattaatct acataatcgt aaaccatatc
     3121 ctactatagc tactaaataa cattatagca aattctcaag ttttaataaa gttttacgga
     3181 ccatattaaa ggcatgtaaa gtagcgatat agcgcacatc caaacgactt cgcccgctaa
     3241 tcaaaacctt tattgattct accttatttt gagtggcaag accaatgaaa actgtacctg
     3301 caggctgttc ctccaacata tctggtccgg caacacctgt taaacttacc ccaatatcag
     3361 caccagtcaa taaccttgct tgctccgcca tcccctcggc tgtataagca ctaacaacgc
     3421 catgcgattt caactcctct aaaggaaggc ctagcatttt cgctttttct tccatgctat
     3481 aagtcacaaa gcctccattg aatacttgag aagctcctgg aaaactcgcc aaagttgact
     3541 gaaataatcc cgcggttaga ctttctgctg ctgtaattgt cttatcatat tttactaaga
     3601 gctcaaatgt ctcacgcgct aaggaattat cctccccata gccataaaag acatcagcta
     3661 agggttgacc ttcaagagtt tttcgggata gtagctgcgc ttctagctga cctaactttt
     3721 tatctgccag agcttggttt tcagtttttg ttgataagcg aagagtcact tcgccagtct
     3781 tagcatacgg agcaatggtt ggatcagttt gattctcaat aaaatctgac aagactgtta
     3841 ccaactgact ttccccaata ccaaaaaagc gtagtacctt tgaatacaat gtactgtatt
     3901 gttttgacag aagtggtacc aattcttcat ttaccatcgg cttcaattca cttggaggac
     3961 ccggtaagac aacataacta ataccatcga ctgtgatgaa cccaccaacc gcaagaccag
     4021 ttttatttgg caaagggatt gacccttcaa tcacttgtgc ctgtcgctca ttatttggtg
     4081 tccgtgatga aggcttgcgc ttagcaaaaa agtcatctag tttctgacaa gcttgcttat
     4141 cataaaccaa gtctttccta aggtactttg ctaaagtttg tttggttaaa tcatctttcg
     4201 ttggaccaag gccaccgcat aaaatgacca agtcactacg ctgactagca gttgtaatca
     4261 ctgaaagtaa acgctcctcg ttgtccccaa cagccgtttg aaaatagaca tcaataccta
     4321 gctctgccat tttttccgac agaaattgag cattggtatt cacaatttga ccagtcaaaa
     4381 tttcggtacc tactgcaatc agttcagctt tcatttcccc acctacttat ctattcgtaa
     4441 tctgatctca ttttatcaaa aaatcttcca attcacgaag aattagaaga ttctattgaa
     4501 aacacaagcc tcttcatggt catttaccag acccgatgct tgcataaaag aataaaccgt
     4561 tgtaggccct aaaaatttaa atcctctttt ctttaaatcc ttagctaagc gaatagataa
     4621 ttctgtttga gcaggaacaa gattctcttg attgacaagg ttgttaattg gctttccccc
     4681 aacaaaattc cagagataag ttgaaaaact accaaactct tcttgaattt tctgtactgc
     4741 gatagcattg ttgacagttg ctgctagctt tagcttgtgg cggatgatgg atggattctc
     4801 taaagcgtca gccatttcct ccgaggtaaa ggctgcaacc gatgcaatgt cgtaatgatg
     4861 aaaaacagtt ctgaaagctt ggcgtttttt caaaacagtc agccaggata agcctgactg
     4921 gtaactttca aggcagagtg attcaaaaaa atctctatca tcatgtaggg gttgacccca
     4981 ttctaaatcg tggtaatcac agtaaagctg gttatcctta ggaacccatg aacaacgttt
     5041 catgtgaaac acctagcctt tcattaatag tttaagggct gatttgatgt attgttcggc
     5101 cgtttcagag gttccttcaa agaaggcacg aattttcttc aattccgctg ccttataacc
     5161 gagggcaagg agggcttcaa tcgcttcgtc cagttgagta ttgcctgctt tattgctgcg
     5221 cgctttggta ttaccagtct cttgtggagc ctccacaaat ttgccagcta agtcaagaac
     5281 catttgctgc gctgtttttt taccaatttt aggaaatttc attaggtact taatgtcact
     5341 gttatcaatg gcattcacaa gtccctcatt atcatcaact gctacaatag caagagctgt
     5401 tgtggggcca atgccagata cagaaattaa tttcagaaaa acatcttttt cgtcttccgt
     5461 atgaaaccca aacaacaagt gagcatcctc acgaatcact tgatgcaggt aaatagttac
     5521 cagttggttg acactatctg taaagctata aggattggct acattgataa tatagcctag
     5581 tccatttgtt tcaacgacaa tgtattttgc cgtaattttg gtcaattgac ctttaatata
     5641 atcgtacata ctacaccttt ttcatttttg cagaaacaac cgtaaaataa atccctagca
     5701 aagcaatgac tacaaataag cattgcacac ctaaaggacc tgtaaaatgg ctgacagata
     5761 ctagtagact agccaaaata gcacctaggg gttgtgccat tgacacaaaa cctgtataag
     5821 atcctatttg ggaatgatcc atcatattag cacgtaggac ttgactagca ggaacattta
     5881 tcatttcccc aaaagttaac aaaacaactg atagccaaat agcatagaac tgcgtaaagg
     5941 taaatgccaa gagcatccct agagtaaata gtaaagaacc aaccacaagc tgaggtaata
     6001 gtttccattt ttccgttaat ttatttacta ctgtcatgaa aaggacaatc agcaatgtat
     6061 tagttaaaac cattaatgat aacattttag aactagttac ttggaaacct aacacagccg
     6121 ttggctgaaa atacagtttc aaatggactg gcacatagtt atccatctgc atccaaatac
     6181 taccagaaaa gatggcacct aaggtaaaaa agacaaaggc acgatcatga aacacctgac
     6241 ggtagttctg aaaactcgcc agtaatcctt taccatggtc aaaagcgtgt gtttctggtc
     6301 tagtctcatc aaaatagtag taagcaacgc caaaacaaag tacattaacg agtaataagg
     6361 ctactaacaa ggctaaaaaa tgatggtcat aaaaaagccc agatagccct gcaccaaaca
     6421 tgacggcaat attgataaac caataattga tggtgtaaac aaatcgacga ttactctcat
     6481 cagtcaaatc aattaacata gcttcatagg caggaccata aaaactagaa gcaatctcta
     6541 ccaataaaat acccgcaaag gttaaccaag gaatagctgc attaggcaaa ttagctaaaa
     6601 tagtcagaaa ccagcctagt gttgttccta ctgacccaat cataatgact tttttgcgac
     6661 caagagcatc tgacagatgc ccaccgtata aagttccaac aaatcccatc aaactggtaa
     6721 tcatcattaa gaggcctgtc caaaacgtac caaagtaagt cgtataatac atggccataa
     6781 agggaaaaat actactgcct aaggtaatgg tcacaaagcg taccagttgc ctcagctgaa
     6841 tctgcttagg aaggtttaaa aactcttgca tctcatcctc tctaatattt tcctagctct
     6901 cgcaggctag tgtgattttc ttggatacga cggaacattt tttccatatc tgccttacta
     6961 aaattaatca atacgggtct accatgaggg cagttataag gattttgaca ttgggccaat
     7021 tgcagtagca gatttcttgc tgaataatca tccaagctat gatttgcctt gatagatcgt
     7081 ttacaactca tcataatagc taactctgct cggtaagttt taatagatac ctcattggtt
     7141 agaagtaaca tgtcacacat ttcatagaca ccagatgcaa tctcttcttc tttcatccag
     7201 ataggatgct ccctcaaaat gaaagtattg tgcccataaa cttctaagaa gacaccaact
     7261 tcatttaaga gtgccatttt ctcctgtaag ttaatgaaat cagaaccaga aaactcaaac
     7321 aaatagggca ccaacaattg ctgtaaacta ctgtcaacct cacctatctt atcacgataa
     7381 tattcgtatt taacccgctc ttgagcagca tgctgatcga taataaataa gccatcttta
     7441 ccttgagcaa agagataagt tccgtgcatc tgaccaaaat aatccaattc gggaaacact
     7501 gattgctctt cattttccaa acgggttagc atttgagata acttttgtct gttttttaag
     7561 tcaagattag gatgatcagt ctcggtaaag gtattctggg gacgacttgc gtgtttaacc
     7621 gaagaaggtc ctataacttc ttctgagtgg ggtaacagct ctgctttttc aacctttaca
     7681 ctgttgtcaa cagcaccgga ataaaaatca gtttcaggta ttttttccga gacagccgac
     7741 tctttgacaa aaaagtcatt cttttgagga tcataataaa gccccctaga ctgtaaagga
     7801 agttgtgttt gctctggttt agagaaatgt cgtgtgcttg acttggctaa gttttccaga
     7861 gcatctggaa tcaaatcttg ttccttaaga ctctctgaaa tagccgtgct aattaaagcc
     7921 attaattcac gctcttttga aatacgaacc tcttgttttg tggggtgaac attgacatcg
     7981 gccaaatagg gatcaatctg aatatcaatc acaacaattg ggaaacgtcc aaccatgagc
     8041 ttagaaccgt aaccatcaag aattgctcga ttaagcaaga aattcttgat gtaacgccca
     8101 ttaaccaaaa tcgtcatgta attacggttg gcgcgtgtca actctggcaa gctaacatag
     8161 ccggaaactt caaaatccaa atcagcatta gagatagcca gcattttttt ggtagtattc
     8221 aaaccataaa tccctgcaat tgcttggcgt aaatcgccag ttcctgatgt ctgagttaat
     8281 tggcgaccat cactaatcag tgtgaaagca acttctggat gtgccaaact caaccggttg
     8341 accacatcta caatgtgagc taattctgcc tgtaaacttt tcatgtattt gagacgagca
     8401 ggcgtgttgt aaaaaaggtt ttcaacctta attttggttc cagtaggagt tgagatcgct
     8461 tcaagtgtct caatttcccc accagtagct ataagaagag aaccgtgagt gacttctttt
     8521 gttgctgttt ttatcgtgat tttactgata gaggcaacag acggtaaagc ctctccacgg
     8581 aagccaagtg ttctaattct aaacaaatca ctctgactct taattttact agtagcgtgg
     8641 cgacgcagac ttaaaggtaa atcttcatga gacattccct caccgttgtc tgtaacctgt
     8701 atcatcttaa ggccagactc ttcaatttca acggtaatct ggctactttt agcatcaata
     8761 gcattctcaa ccaattcctt gacaacactc gctggccttt ctacaacttc accagctgca
     8821 atttggttgg cgagaacttc cggtaattca ataatgtttg tcataatttt gtttttaaca
     8881 ctttctaaac gttgatataa caaggtttca ttaggtttac acctctcaaa atattaattt
     8941 gtggactttt ttgtggactt ataaattatt catagccttt tcataatata aaacagcttc
     9001 tttttctttg tccttagaaa gatggccata ggtatccaaa gtcatgctga tattcgcatg
     9061 tcctagacgg tactgaagtt ccttataact aataccagcg ttcagcaata aactagcgtg
     9121 agtgtgtcta aaagcgtgaa aggtaaagcg ttcaatccct gcttccttac acctagtatc
     9181 taaaacgctt tgtctaaccg aagcattaaa atactttcgt gttggtgtgg caaacactac
     9241 ctccgacaca cgcgcaccaa cctcattaaa taattgtcgc tgtctcattt gatagagctt
     9301 taggcttcta agggtctttt tatcaacact aatcactcta ttgcctgact gggttttagc
     9361 tgtactcaaa aacttcaaat ttttattgta agtcttatta atggctattg taccattttc
     9421 taggtcaata tctccccact ctaatgcaca ggcttcgcct atcctcaagc cagtggataa
     9481 taaaagttgg tagagaactg catcaaagta aaggttatag cgtttgtgtt gactagtttc
     9541 taaatgttct aaaaaagatt tcaaatcaga cagatcaata aacttaactt ttttcttagc
     9601 gtttggctgc ttccttggaa ggataatatc tcttgctgag ttataatcta ttagccctag
     9661 caatactcct tgttggagaa cttttcggat gactgaacgt accgcagtat aattgacgta
     9721 atatttagat aatctattaa tcagcatttg aatatcacta gcggttatct tatcaacctt
     9781 catattgccc agagttggca taatatgtcg attaagtcta gtaacagtag catcataagt
     9841 ttgaggcttt actgttaact tataggtttc aagccataaa tgactaagtt ctttaaatgt
     9901 tttaatcaca acttttcttt taattgtaga tccattagat aggaagtcaa gctgcgcgtg
     9961 cttggctttt tgattaactt cttttcttgt tcttcctgtg atgcttgttt ttactctctt
    10021 acctgtcatt tggtcaatgc ctagataaat actagcacga taaacgattg taccgttttt
    10081 cttcttatgt tctgttattt tcatgatcat aaacctttcc atcagcaggc aagctattat
    10141 taaaagggtt ttagattagt tcatatcatg gtataatatt agtcttttta agaccttgcg
    10201 aacgtggaaa acttgcgggg ccttttttat ttggttttgt aaggtataga gagtttcaga
    10261 agaagttttg catgtctaaa aactaggtca aggtttacat agattcgagc tcttgagaat
    10321 gtctgtccct atgatacaat aaacctcgta acaaagtaaa agacggtagt cgtagcctta
    10381 tgtctagagg tgatgcttat gtatgtaagt cacagaaacc aaaagaaagg agacgacaag
    10441 gtttgtcagt ttatgaaacg cttactttga tgattgcctt tggtactctg atagtagcta
    10501 tcatgaataa caagaacaaa tagaaaaacc gtcccacact ttagccaatc gtggacggtt
    10561 tatagaaaat ataaacaaat acggtaaggc tgccgtctta aacggtgtta ccacaggaga
    10621 ttgtttgcgc aatctccttt ttctatgtcc attatagctt tgtttgataa agaagtcaaa
    10681 gggtatagtt agaaagtata gtctttagcg ctcttagcat tccttagtgt taccaaaatg
    10741 aataaaaata attttatgca agaatttata atgctttatg caaccactga ccacacgcag
    10801 acagtttttt taattaccgc cgacaaaaag ttcagattat acctcaattt ttgtcaactt
    10861 ttgagggtct tgtaattaaa gaaaattaaa ggcgtatcaa agtatttgcg cgtaggtaaa
    10921 gataataaaa ttggcattta gacatgaaaa tttaacaggt cgttattgag tggtaactgt
    10981 aaggtagcta aatttgttcc acgcgcataa tgctgaactt cgagcgaact tagagaatag
    11041 aaggttacta ctcccaaaca cgaacacatg gtcgcatttc ggaatgctgg aaaatgttgg
    11101 cacatactga cataatacgt caacctattt caatagttgt aaaacgctcg gtaaattcac
    11161 ttaaagaact tgatatatcg gtcgtttatt aatttacttt ttccgttgtg acagcttcta
    11221 aaatcagttg atatttttag cgtatagtat ccagaaaatc ggactttttt ccaccctaaa
    11281 aagtgacaag gtttatacaa ggtcagcgga cttgctgaag cacgagggaa gcacgcgctc
    11341 agagtggatt gtgtacatac ttttctatac agtggcgcgt gggttagtct actttgataa
    11401 gtttatctat ttggattgct ttaggagcat gactgttccc gtaactatca aaaaatgaaa
    11461 caatgacctt gtcattttta ttcaaaacaa tttcagaaag atactctttg tctggatgga
    11521 aatcatatcg atatgcagaa atcactgccc cagaattaag gtagtgtttt tttaatactt
    11581 caattacatc attataaaaa tgcgtttgaa aagaaattgg taaggaagat ataaagtcat
    11641 aaaactcatt atatccataa tttccgctat cttcatccaa tgacagacgt acccaaagtt
    11701 taacagttgt gtcgtcagta ggtgaatcaa tgtgtttagg tgagaaaaag aatagtttga
    11761 gtatataaac tctttcacta tgggtagatt tgaggtttat agctataaga ttatcccctt
    11821 cttctttgta ttcataatct tctttattat aagctttcca aatatacgga ctataaacaa
    11881 agaaatcttt taattctatt cccaagtaat tacacaattt atcaactgta tcaaattgca
    11941 cccctttacc agtgttttct gataaagcca tgagtgtagt ttttgaaata ccagtatctt
    12001 cataaacatc tgctatttta aggccgcgtt cggccattaa gacagcaaaa tttgttttaa
    12061 tcatttgttt tagacctccg tacttaaatt ataactaaca ttatttaaaa aaacaaacat
    12121 caaaaaaata taacaaagta ttgac
//
LOCUS       DAUGSW010000038        10902 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUGSW010000038 DAUGSW010000000
VERSION     DAUGSW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10902
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.038"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            36..4136
                     /locus_tag="VIB18_001367"
     CDS             36..4136
                     /locus_tag="VIB18_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding adhesin SdrG C-terminal
                     domain-containing protein"
                     /protein_id="HEQ8766369.1"
                     /translation="MYSRLKRELVIVINRKKKYKLIRLMVTLGLIFSQLAPPFGTLMA
                     LSGHSRSKSPVTEVKADSVSTPKTGSFKLKKFDEDGKTPIKDVTFQLTSETNPSNYKI
                     EQTTSDAGDATFANIPPGTYLLKEVAPPSGYQVMTDYYKITVSPDGYTQYTYVKVGTT
                     TSSPTTSLPSLSGGGTGGTVLRTPKTSGVVTVTDYNFTTKNKAQGNTDYTKLWATSGE
                     FFDMSFKLKVNEGTQAGDSFTIKLSDYLSPNGIREKFISAPPLMLDQQVVATGIYDEA
                     TNSYIYTFNDLINHKQNAEIKVNYTFSPEAKKVDREWYVNTYNITNTIDGQKQDSGNF
                     TIDYGEGQYMAGSLNDGLRLRNNITYLNRTTGEVEYTIYLNNGAPSRDSKYTVSDPWV
                     ALHYVNIAEKSSVVSFNKDDITVYRVPLSQKTTMMPYSMSGETDGLTTIPVSYDGQGF
                     SLPKRSFLDSETGKNTAGILIKIKAKINSSLRNADVSLNAIWKYTQVGGQSNAKASVF
                     ELGNTSSGVANNIEPTVTIRNYKTKKGSIVFTKQDVETKKALSGVAFKLEKKEENDWQ
                     VVEKYKDVQTGTDGKLILSDLDAGEYQLIETKPLDGYLAVSGPVASFTITDQGLETSI
                     KPSDKIIPNTKPGKQKIKVIKKDEQSRVPLAGAKFQLESNKGVVLTGETDGKGEYTFT
                     NLPFGDYILTEIAAPKGYILDKTPRSIAIGDTVDKEPEPTVVEAATPRTVRSVSPSAT
                     VSGKDVSRNILVKKVEFTTTNGQTPLQVKPNQGENLIARSEFELKKEIDIKKGDYFAV
                     KLSDNIDPFGVSTGETTTFNITGPYGTLAVGKYDHQSRSIIYTFTDYVEKYDVSNFST
                     ILPYFIDRYAVTSDADINISTSVGSQTNNAQVRVLYTPYYGYTDSKSPVNVGSMLTKL
                     DLKNKTFTNYVYINPKHESIRNGKLYFVGDGAAIINEATHITLYKALNNADMPPSWGV
                     TDDNLTEEVSLPIVKENGRIYIDFGNSLQYRDSFILKIVGHYDADSDAPIKTSATLYQ
                     NYYNYYGYYTEKGRWIPQGPYSEYFTYNAGAVLKSGESSADGALRVTVTNRKNNVEFM
                     KTNAAGTPLEASFELRKVKPDKTFTNLKTVKSDKDTGKFAFEGMESGNYEVWETQVPS
                     GYLKPDKAVATFKVDKDGTIKDLTPDNGKIINYPNTAKIIFTKMLASEKGELSPATKE
                     KSATFSLWRRKDSNGKEIDTPTQAYDEQYYEPVLMNGATRTATSDDKGNVLFDNLSPG
                     FYAIKEESAPDGYVKQKGIVRIFQVDATGKVIKYRLLNDKIVTDKLVEIKESDGDLQK
                     EFNEIINHKFVFPMTGGQGITLFMVVGGAIMGIAYLGHRRKQRLND"
     gene            4257..6392
                     /locus_tag="VIB18_001368"
     CDS             4257..6392
                     /locus_tag="VIB18_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEQ8766370.1"
                     /translation="MKTKIFSRLAAVLLVLGSLLPTVVAVAEAESSHKTDVVIHKIKM
                     TSLKGWPKEKNPDGTYTGENSKIYNGEKINDISQYFGAKSGAEELDGVSFIYWKVDKK
                     EDYEKLTKNPQNYDTVLKVQALLKNAGESSGTTTEKTANQKGVKVANLTDGYYWFVEN
                     SGSNIANGETLSSSAAVPFGLELPAYKADGSMIEELHVYPKNTTTKPKIDKNFSIEEK
                     DAKLAGGAKYEYYQKDKGHVSRTVGAEVSYQIKTEIPAGAQYQTLRWEDTMTKGLTYK
                     NGSLNLGITHSGNNIDNFKVGTDYSLTENQSGFVLKFTESGLEKVKKAVQATKNDKGQ
                     ITDDGNPMTVELTYKATVNSDAVVDQPDKNTVIFDYGNNPKEYKDPRDKSIKPKDRSI
                     TVNKIWASQPAPSGVEVTYYLYQKGTTANEDKVVDSVILTKDYNHTFTNLDDSKDYYV
                     KESAIGYIPEYTSAQDGTISIKNTKDDKNPDPLKPTSPAIVTHGKKFVKTSQEDERLQ
                     GAAFVVTNQKTGGKYLAIKADNEQNAEEKAYQEAEKKYQEEIKKATTDKPNTLEIEKA
                     KKARDDAFKKARTAYQWVDDKEKAIKLTSNSKGQLELTGLAAGTYYLEELTAPIGFAK
                     LQERVEFKLGFNSYNGHKDQSGQSLEGHIQYEKGTPDFGYGQRIINKKITIPQTGGIG
                     TVIFTMVGLAIMTVTGLMMIRRNKNDKSE"
     gene            6405..7250
                     /locus_tag="VIB18_001369"
     CDS             6405..7250
                     /locus_tag="VIB18_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HEQ8766371.1"
                     /translation="MGGTQLKIGRLIRLMLSICACLYFLTSPIFALQKTSSVTIHFEK
                     SDKDTQLALWQLPEGQTLPELETLFEKTDAELTHQYPQVSTVTVPKGETKLVLSNLPV
                     GAIYYVREAEERLGVHSLAPFILKVDTDDDQAVYTKKAKPQKRGSYPFVKVSAQGGSL
                     EGATFEVWKQTQKQLQPVIKGGSRYLLTSSKDGSFMAKDLPFGSYVLKEITAPKGYLL
                     SKKTISFEVTDYSEKQAPVKVVNQPKIPPRIEIPYTGNAIMILVVLLSFALFTLGVYL
                     VRKNG"
     gene            7332..8168
                     /locus_tag="VIB18_001370"
     CDS             7332..8168
                     /locus_tag="VIB18_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEQ8766372.1"
                     /translation="MKQQSKRHRLNQNIALIVVFLIGLTILLYPQISRIYYTIESNNQ
                     SKQFDREKSTLHQEDISQRIALAKAFNASLHDVNLKDPYSDDEKTKGRAEYARMLELH
                     EQIGHVEIPKIRVDLPIYAGTSDEIISKGSGHLEGTSLPVGGENTHTVLTSHSGLPSA
                     KLFSDLAKLKKEDIFYIHNIKEILAYQIDQIKIIEPDNFSDLLIVPGKDYATLLTCTP
                     VGINTHRLIVRGHRVPYVSNEHKNNKQKASSGYMCYLFVLLALLTLLFGYWFYRQKKK
                     KS"
     gene            8191..9024
                     /locus_tag="VIB18_001371"
     CDS             8191..9024
                     /locus_tag="VIB18_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEQ8766373.1"
                     /translation="MLKNKQSLSLRERLIQVMFPLLFLMGCLIVLYPLMSNYYYRVKQ
                     NQAVTSFESAKVIVNKDDIKRRMALARAYNATLDPGRINDPYTDLEKKGVAEYARMLE
                     LNEQIGYIEVPRFDINLPIYAGTSDDVLQKAAGHLEGTSLPIGGDSTHTVITAHTGLP
                     QAKLFTNIHKMKKGDLFFIHNIDKTLAYKVDQILVVEPDNFTPVLVKNGFDYATLLTC
                     TPYGINSHRLLVRGYRVPYQKAFEKADAQRPWYTKAIFLVSFLLFVILVIILLINWHR
                     K"
     gene            9044..9901
                     /locus_tag="VIB18_001372"
     CDS             9044..9901
                     /locus_tag="VIB18_001372"
                     /inference="COORDINATES: protein motif:HMM:NF033745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEQ8766374.1"
                     /translation="MSKQKCVGYVLMILGLGLPLFFLTLMSLNQFQEQVAYQKFQTEN
                     RSWKNSQKEWVNRHNQEQALTDRATTDPFVDAQNQLKQSPFDDNIIGYIIIPKLRMAQ
                     PIRVGASERHLEKGVAQVTGTSLPIGGLGTRSVIAGHRSWYDNERFLRIAELSIGDQI
                     VIDLGVYQLEYRVKSVEIIDAKDWRQLTAKKSQDLITLLTCNPLYPPFNERLLVNAER
                     VSPSLSDLPTKTRNKMDQSQLESPLASHKTSLVKLPLVLPFGIWVCLGWLIESYFIYR
                     LFHQCKGDS"
     gene            complement(10244..10855)
                     /locus_tag="VIB18_001373"
     CDS             complement(10244..10855)
                     /locus_tag="VIB18_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766375.1"
                     /translation="MLFSSYKSVHAHDNIDEKGKVHLYWQGNYYVDNYVDYTKTLVDN
                     SIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPTQITVQDHWQNGKIDSKTVQNTQWHYD
                     WENQQTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHVLVDTYGRQSHTYFSHKMV
                     WKFKTELEEGYKNKWDKLPFIAGIKQNNPLAASFPSYKGEFGE"
BASE COUNT         3666 a         1878 c         2246 g         3112 t
ORIGIN      
        1 tagatatgtt agaaactgta tttttgtaaa gtttaatgta cagtagattg aagagagagt
       61 tagttatagt gataaacaga aaaaagaaat ataaactaat tagactgatg gttaccttag
      121 gccttatttt ttcgcagtta gcacctcctt ttgggacttt aatggcttta tcaggacatt
      181 cgaggtcaaa aagtcctgtc acagaagtca aagctgatag tgtgagtacc ccgaagacag
      241 gaagttttaa gctcaaaaaa tttgatgaag atggaaaaac acccattaag gatgtaacgt
      301 ttcagttaac atcggagacc aatccgtcaa actataagat tgaacaaaca actagtgatg
      361 caggtgatgc aaccttcgct aatatccctc caggaacata ccttttaaag gaagtggcac
      421 caccaagtgg ttatcaggtg atgactgatt attataagat aaccgtcagt ccagatgggt
      481 acacacagta tacttatgtc aaagtaggga caacgactag tagcccgaca acctctcttc
      541 cttcgctaag tggtggagga acaggtggga ctgtccttag gacgccaaaa acctctggcg
      601 tagtgacagt aactgactat aactttacaa ctaaaaataa agcacaagga aatacagatt
      661 atacaaaatt atgggcgaca tcgggagagt ttttcgatat gtcctttaaa ttgaaggtca
      721 acgaaggaac gcaagcgggt gattctttta ccataaagct aagcgactac ttatctccaa
      781 atggtattcg tgaaaaattc atctcggcac ctcctttgat gctcgatcag caagtagttg
      841 ccacagggat ttatgatgag gccaccaata gctacatcta tacctttaat gatctcatta
      901 atcataaaca gaatgctgaa atcaaagtga attatacctt cagcccagaa gccaaaaagg
      961 ttgatcgaga atggtatgta aatacctaca atattacaaa tactattgac ggtcagaagc
     1021 aagattctgg taactttacg atcgattatg gtgaaggcca atacatggca ggttcactta
     1081 acgatggcct taggttaagg aataatatta cttaccttaa tcggacaact ggtgaagttg
     1141 aatataccat ttatttgaat aatggagcac cgtctagaga tagcaaatac acagtatctg
     1201 atccatgggt ggcgttacat tatgtaaata tagcagaaaa atcgagtgtt gtgtcattca
     1261 ataaggatga tattactgtt tatcgggttc ccttaagtca aaaaacgact atgatgccct
     1321 acagtatgtc aggagaaaca gatggcttga ctactattcc tgttagctat gatggtcaag
     1381 ggttctcact gccaaagaga agctttctcg attcagaaac tggtaaaaat actgcgggta
     1441 ttttaatcaa aataaaagct aagattaatt cttcgcttag aaatgcagat gtctctttaa
     1501 atgctatttg gaaatacaca caagttggag gacaatccaa tgccaaagcc agtgtttttg
     1561 agttaggaaa tacatcatct ggggtggcga ataatattga gcctactgta accattcgta
     1621 actataaaac aaaaaagggt tcaatcgtct ttacaaagca agatgttgaa actaagaagg
     1681 ctttgagtgg tgttgccttt aaattagaga aaaaagaaga aaatgactgg caagttgtcg
     1741 agaaatacaa ggatgtccag accggaacag atggcaagtt aattctgtca gacttagatg
     1801 ctggagaata tcagttaatt gaaacaaaac ctttagacgg ttatctagcg gtatctgggc
     1861 cagtagcatc ctttacgata acagaccaag gattagagac ttcgatcaag ccgtcagata
     1921 aaatcatccc gaacacgaag ccagggaaac aaaagattaa agtcattaaa aaggatgagc
     1981 aaagcagggt accattagcc ggagccaagt ttcaacttga gtccaataag ggtgtggtac
     2041 taactggtga gacagatggt aagggagagt atacctttac aaacttacca tttggtgact
     2101 acattttgac agagattgcc gcgccaaaag gatacatttt ggataaaaca cctcgctcta
     2161 ttgcaatagg agatacagtg gataaagagc cagaacctac ggttgtggaa gctgctaccc
     2221 caaggacagt ccgatcagtg agtccttcag caacagtgtc cggcaaagat gtgtccagaa
     2281 atattctagt caaaaaagtt gaatttacta caacaaatgg tcaaactccc ttacaagtta
     2341 aacctaatca aggtgaaaac ctgattgctc gatcagaatt tgaacttaag aaagagattg
     2401 atattaagaa gggagattat tttgcggtta aactctcaga taatatagat ccctttgggg
     2461 tttcaacagg agaaacaaca acctttaaca tcactggtcc ttacggaact ttagctgttg
     2521 gtaagtatga ccaccagagt cgcagtatta tttatacttt tacagactat gttgaaaaat
     2581 atgatgtttc aaatttttca acgatcttac catactttat agatcgttat gctgttacta
     2641 gcgatgctga tattaatatc tcaacaagcg ttgggagtca gacaaataac gcgcaagttc
     2701 gggtgctcta tactccttat tacggatata ctgatagtaa atcgcctgtc aatgtaggtt
     2761 ctatgctcac taagctagat ttgaaaaata agacctttac aaactatgtc tatattaatc
     2821 ctaagcatga gagtattcgt aatggcaaat tgtatttcgt gggagatggt gctgctatta
     2881 taaacgaggc aactcatatc actctttata aagcacttaa caatgcggat atgcctccaa
     2941 gttggggagt gactgatgat aatttaacag aagaggttag tttacctatt gtcaaggaaa
     3001 atggaagaat ttatattgat tttggtaata gccttcaata cagggattca tttatcttga
     3061 aaatcgttgg tcactatgat gctgattctg atgcgccgat aaaaactagt gcgaccctgt
     3121 atcaaaacta ctataactac tatggttatt ataccgagaa gggacgttgg atacctcaag
     3181 gaccatattc agaatacttt acttataatg ccggagctgt tttaaaatca ggtgaaagta
     3241 gtgctgatgg tgcgcttaga gtaaccgtga ctaaccgtaa aaataatgtc gagtttatga
     3301 agaccaatgc cgctggaacc ccactagaag ctagctttga gttgcgcaaa gtgaagccag
     3361 ataaaacatt tactaatcta aaaacagtaa aatctgataa agatacgggt aaatttgctt
     3421 ttgaaggtat ggaatcaggt aactacgagg tctgggaaac acaagtacca tccggttatc
     3481 tgaagccaga taaagcagta gctactttca aagttgataa ggacggtaca attaaagatt
     3541 tgacacctga taacggtaag attattaatt atcctaatac tgctaagatt atttttacaa
     3601 aaatgttggc ttctgaaaaa ggggaattgt ctcctgctac gaaagagaag tctgcaacgt
     3661 ttagtttatg gcgacgtaaa gatagtaatg gaaaagaaat tgatacacct acacaggctt
     3721 atgatgagca atattatgaa cctgtcttga tgaatggtgc tactcgaaca gcaacttcag
     3781 atgataaggg taatgtcttg tttgacaact tgtccccagg tttttatgcc atcaaagagg
     3841 agtcagcacc tgatggttat gtgaagcaaa aaggaatagt tcgaatcttc caagtagatg
     3901 caaccggaaa agtcattaaa tatcgtcttc ttaacgataa aatagtgacc gataagctag
     3961 tagaaattaa agaatcagac ggagacttac agaaagaatt caatgaaatc attaatcaca
     4021 agtttgtctt ccctatgact ggtggtcaag gcattacatt atttatggtg gttggtggtg
     4081 ctattatggg gattgcttat cttggtcatc gtagaaaaca aagattaaat gattgatggt
     4141 tgttatttga atattgtgga gaccctcctt ttagagaggg agttgccagt aatttaacaa
     4201 tcaaaagagt caaaaaaaca tttagataaa tattttttac aaataggaga gaacagttga
     4261 aaacgaagat atttagtaga ttggcagcag tattgctggt tttgggaagc cttttaccga
     4321 cagttgtagc tgtggcagaa gcagaatcat cacataaaac cgatgttgtt attcataaaa
     4381 tcaaaatgac gagcttaaaa ggctggccaa aagaaaaaaa tcctgacggg acttatacag
     4441 gagagaatag taaaatctat aatggtgaaa agatcaatga tattagtcaa tacttcggtg
     4501 ccaaatcagg agctgaagag cttgatggtg ttagctttat ttactggaag gtagacaaaa
     4561 aagaagacta tgagaagtta actaaaaatc ctcaaaacta cgatacagta ctaaaagtgc
     4621 aagcactttt aaaaaatgcg ggggagtctt cggggactac tactgaaaag actgctaatc
     4681 aaaagggtgt caaagttgcg aatcttacag atggttacta ttggtttgtc gaaaactcgg
     4741 gttccaatat tgcgaatgga gaaaccttgt cttctagcgc agcagttcca tttggtttgg
     4801 aattgccggc ctataaggct gatggatcaa tgatcgaaga gttacatgtg tatccgaaaa
     4861 ataccacaac aaaaccaaaa attgataaaa actttagtat tgaggaaaaa gatgcaaagc
     4921 tagcaggtgg agcgaaatat gaatattatc agaaagataa aggtcatgta tcgcgaacag
     4981 ttggtgcaga agtttcttat caaattaaaa cagagattcc ggctggtgcg cagtatcaga
     5041 cccttcgctg ggaagatacg atgacaaaag ggttaactta taaaaatgga agtttgaatc
     5101 ttggaattac tcattcaggt aataatatcg ataattttaa ggttggaaca gattatagcc
     5161 taactgaaaa tcaaagtgga tttgtcttga aattcactga atcaggtcta gaaaaagtta
     5221 aaaaagctgt tcaagcaact aagaatgata agggtcaaat cacagatgat ggtaacccaa
     5281 tgacagtgga gctaacctat aaagctactg tcaatagcga tgccgtcgtt gaccaaccag
     5341 acaaaaatac ggtgatcttt gattatggta ataatcctaa agaatataaa gacccaagag
     5401 ataagtcgat aaagccaaaa gacaggtcta ttacagttaa caagatatgg gctagccaac
     5461 cagcgccttc aggtgttgaa gtgacctact acctttacca aaaaggcacg acagcaaatg
     5521 aagataaggt ggttgattct gttatattaa ccaaagatta taatcatacc tttacaaact
     5581 tagatgactc caaggactac tatgtaaaag aaagtgccat tggttacata ccagagtata
     5641 cttcagctca agatggaaca atttccatta agaataccaa agatgataaa aatccagatc
     5701 ctcttaaacc gactagtcca gcaattgtaa cacatggtaa aaaattcgtt aagacaagtc
     5761 aagaagatga gcgtctacaa ggtgcagcct ttgttgtaac taatcaaaaa acaggtggta
     5821 agtatttagc cattaaagct gataatgaac aaaatgctga agagaaagct tatcaggagg
     5881 ctgagaaaaa gtaccaagaa gagattaaga aagctactac agacaagcct aatacattag
     5941 aaattgaaaa ggctaagaaa gcgcgtgacg atgccttcaa aaaagcaaga actgcttatc
     6001 agtgggtaga tgataaagaa aaggccatta agttgacatc aaacagcaaa gggcaactgg
     6061 agctaacagg gcttgctgct ggcacctact atttagaaga attgacagct cctatcggct
     6121 ttgcaaagct tcaagagaga gttgaattta agcttggttt caactcttat aatgggcata
     6181 aagatcaatc tggtcaaagt ttggaaggcc acattcaata tgaaaaagga actcctgatt
     6241 ttggttatgg acagcgtatc atcaacaaaa aaatcaccat tcctcaaact ggtggtattg
     6301 gtacagttat ctttactatg gttggtttgg caatcatgac cgttactgga ttgatgatga
     6361 tccgtcgtaa taaaaatgat aaatcggaat agtttgttag aaaaatggga ggtacacaat
     6421 tgaaaatagg acgattgatt cgcttgatgt tatcgatctg tgcttgtttg tactttttga
     6481 cgtctcctat ttttgctttg cagaaaacgt catccgtgac gattcatttt gagaagtctg
     6541 ataaggatac acaactagcg ttgtggcaat tgcccgaggg acaaactttg cccgaactgg
     6601 aaacactatt tgagaagaca gatgctgagt taacccatca gtatcctcaa gtatcaactg
     6661 tcacagtacc aaaaggtgag accaagcttg tattatcaaa tctacctgta ggagcgattt
     6721 actacgttag agaggcagaa gaacgcttag gtgttcactc gctagcgccc tttatcttga
     6781 aggttgatac agatgatgat caggccgttt atacaaagaa agcaaagcct caaaaacgtg
     6841 gttcgtaccc ttttgttaaa gtttctgctc aaggtggtag tctagaagga gcaacttttg
     6901 aggtttggaa acaaacccaa aaacagctac aacctgttat taaaggtggc agtcggtatc
     6961 tcctaacgtc ctcgaaagat ggttctttta tggcaaaaga tttaccattt gggtcttatg
     7021 ttttaaaaga aatcactgct ccaaaaggtt atcttttgtc aaaaaaaact atatcatttg
     7081 aagtaacaga ttattcagaa aaacaagccc ctgtgaaagt cgtcaaccag cctaagatcc
     7141 ctcctagaat tgaaattccc tatacaggta atgcgattat gattttggtg gttttactta
     7201 gttttgcact atttacacta ggtgtctatc tggtacgtaa gaacggttaa tgaagagaca
     7261 aggcactaag attactagag gtcccgtaag gtgcctctag ttttttaaat aaaaggaata
     7321 aaggtgatag catgaaacag caatccaagc ggcatcgctt aaatcaaaat attgctctga
     7381 tagtagtgtt tttgataggc ttgactattt tattataccc gcaaatttct aggatatact
     7441 acactattga atcaaacaac cagtctaagc aatttgaccg ggagaaatca acgttgcatc
     7501 aagaagatat tagtcagagg atagctcttg caaaggcatt taatgccagt ttgcatgatg
     7561 taaacctcaa agatccctat tccgatgatg aaaaaacaaa aggtcgtgcg gagtatgcac
     7621 ggatgcttga acttcatgaa caaataggac atgtggaaat ccctaagata agggtcgatt
     7681 tgccaattta tgctggaaca agtgatgaaa ttatttctaa agggagtggg catctagagg
     7741 gaacatcttt gccagttggt ggggaaaaca cgcatacggt gctgacgtca cattcaggtt
     7801 tgccctctgc gaaactcttt tcagatttag cgaagcttaa gaaggaagat attttttata
     7861 tccataacat taaagaaatt cttgcttacc aaatagatca gattaaaata attgaaccag
     7921 ataatttttc agatttactg attgttcccg gtaaagatta cgctacgctt ctaacatgta
     7981 ccccagttgg gattaatacg catcggttga ttgttcgtgg gcatcgtgtt ccatacgttt
     8041 ctaatgagca caagaataat aaacaaaaag cgtcatcagg ctacatgtgc tacctgtttg
     8101 tacttcttgc tttacttaca ctacttttcg gttattggtt ttaccgtcag aaaaaaaaga
     8161 agagctagaa agttaagaga gaggagtttc atgctaaaga ataagcaatc attatcgtta
     8221 agggaacgac taattcaagt catgttcccc ttgttattcc ttatgggatg tcttatagtg
     8281 ttgtatccct tgatgtcaaa ctattattat cgtgtgaagc aaaaccaagc agtaacgtca
     8341 tttgaatcag ctaaagtcat cgttaataaa gatgatatca aacgacgtat ggctctagct
     8401 agagcctaca atgccacttt agatccagga aggattaatg atccttatac agatttggaa
     8461 aaaaagggtg ttgcggagta cgcgagaatg ctagagctta atgagcaaat tggttatatt
     8521 gaagtgccgc gttttgatat taatctcccg atttacgctg gaacaagtga cgacgttctc
     8581 caaaaagccg cagggcatct agaaggaacc tctttaccaa ttgggggcga tagcacccat
     8641 accgttatta cagcgcatac tggactacct caagctaaat tgttcacgaa tattcacaag
     8701 atgaaaaagg gagatttatt ttttattcat aatattgaca agacccttgc ttacaaagta
     8761 gaccagattt tagttgtaga acccgataat ttcaccccag ttttagtgaa aaatggtttt
     8821 gattatgcaa cattactaac ctgtacacca tacggaatca atagtcatcg attattagta
     8881 cgcggctacc gtgttcctta tcaaaaagcg tttgaaaaag ctgatgctca aagaccatgg
     8941 tatacaaaag ctatttttct tgtaagtttt ctactatttg ttatactagt gataattctt
     9001 ttaatcaatt ggcatcgcaa gtaatacaga aaggaatagt ttagtgtcta aacaaaaatg
     9061 tgttggctat gttttaatga ttttgggact tggtcttccc ttatttttct taacactaat
     9121 gtcccttaac caatttcaag agcaggttgc ttatcaaaag tttcaaacgg agaatagatc
     9181 gtggaaaaat tcacaaaaag aatgggttaa tcgtcacaat caagagcaag cgttaaccga
     9241 cagagccaca acagacccgt ttgtagatgc acaaaaccag ttgaagcaga gcccttttga
     9301 cgataatatt attggttata ttatcattcc aaagcttcgc atggcacaac cgattcgtgt
     9361 aggtgcaagt gaacgtcatc ttgaaaaggg agtagcgcag gttactggaa ctagcctacc
     9421 catcggcgga ttagggacgc gatcggttat tgcagggcac cgtagctggt atgataatga
     9481 acgttttctt aggatagcag aattatctat tggagatcag attgtgattg atttaggtgt
     9541 ttatcaatta gagtatcgtg ttaagagtgt tgagattatt gatgccaaag attggcgcca
     9601 attaacggct aaaaaaagcc aagatttaat aacgttactg acctgtaatc ctctttatcc
     9661 cccttttaat gaaaggctac tagtaaatgc agagagagta tcgcctagcc tttctgattt
     9721 accaactaaa acgcgaaata agatggatca atctcaacta gaaagtccac tggcgtctca
     9781 caagacttca cttgtcaaat taccgctagt attacctttt gggatttggg tctgtttggg
     9841 ctggttgata gaaagttatt tcatataccg tctatttcac caatgcaaag gtgatagcta
     9901 atacttctga cgacgttcca tcccctctca ttagtttagg taatattagt tactgcatcg
     9961 tttacgttga gccataacct attacaagca gattaaaggg gtgaaaatga gtctatgaca
    10021 aaagcttagc agtttggtca tatcattaac tacaagagac cagagctgct tgttaagtag
    10081 ttcaaaaagg cagagcctta aaaggttttc tgccttttta atcttgttgg gcacttacga
    10141 aagtatttcg gccacttcaa gcataataaa aagagtctga gcaatcatgt tgtctcagac
    10201 tctgactgta attatgcaaa agatgatgga ctggcagctt catttactca ccgaactccc
    10261 ctttataact tgggaatgat gctgctaatg ggttgttttg tttaatacct gctataaacg
    10321 gtaatttatc ccatttattt ttgtaacctt cttcaagctc agttttaaac ttccaaacca
    10381 ttttatgaga aaaataagtg tgcgattgac ggccgtaggt gtctactaaa acgtgagaaa
    10441 attttccgtc gttttttagt ttgtaaaatt tatctagaga aggactccag ccagtataac
    10501 cagggaattt atcaaattct tgattaaaat ttgtttgttg gttttcccaa tcataatgcc
    10561 attgtgtatt ttgtactgtt tttgaatcaa tttttccatt ttgccaatga tcttgaacag
    10621 ttatttgagt aggagctttt acacccttgg gaaggaaaac tgagaaatca gggtaaaccc
    10681 attgttcttt agctgaatta aaggttacag tccattcgat actgttatcg actaatgttt
    10741 tagtatagtc gacatagtta tcaacatagt aatttccctg ccagtaaagg tgcactttac
    10801 ctttctcatc aatgttatca tgggcatgta ctgatttata cgaactaaac agcatcgaag
    10861 ctgctagtag tgaagtgaag agatatttat tacatcgttt ca
//
LOCUS       DAUGSW010000039        10554 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUGSW010000039 DAUGSW010000000
VERSION     DAUGSW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10554
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.039"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            111..434
                     /locus_tag="VIB18_001374"
     CDS             111..434
                     /locus_tag="VIB18_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766376.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSAIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
     gene            491..886
                     /locus_tag="VIB18_001375"
     CDS             491..886
                     /locus_tag="VIB18_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ8766377.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQAEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGQGQVVNPGDGLITIG"
     gene            931..2052
                     /locus_tag="VIB18_001376"
     CDS             931..2052
                     /locus_tag="VIB18_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ8766378.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            2240..2548
                     /gene="citD"
                     /locus_tag="VIB18_001377"
     CDS             2240..2548
                     /gene="citD"
                     /locus_tag="VIB18_001377"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEQ8766379.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEKTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
                     "
     gene            2536..3423
                     /gene="citE"
                     /locus_tag="VIB18_001378"
     CDS             2536..3423
                     /gene="citE"
                     /locus_tag="VIB18_001378"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEQ8766380.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGVLDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            3426..4958
                     /gene="citF"
                     /locus_tag="VIB18_001379"
     CDS             3426..4958
                     /gene="citF"
                     /locus_tag="VIB18_001379"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEQ8766381.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELVNIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEGLVEKILDVQDFDHP
                     SAVSLGKHAEHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            4951..5529
                     /gene="citX"
                     /locus_tag="VIB18_001380"
     CDS             4951..5529
                     /gene="citX"
                     /locus_tag="VIB18_001380"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEQ8766382.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            5544..6938
                     /locus_tag="VIB18_001381"
     CDS             5544..6938
                     /locus_tag="VIB18_001381"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEQ8766383.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFV
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREVGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVITCRPADLIEPQMIYLRDEIAPYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(7048..8100)
                     /gene="citC"
                     /locus_tag="VIB18_001382"
     CDS             complement(7048..8100)
                     /gene="citC"
                     /locus_tag="VIB18_001382"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEQ8766384.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSVYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWELLAKLLPKTSLDYFCSLEA
                     QPIIKKLQATSSVKHY"
     gene            complement(8189..8671)
                     /locus_tag="VIB18_001383"
     CDS             complement(8189..8671)
                     /locus_tag="VIB18_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEQ8766385.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQTHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            complement(9402..10472)
                     /gene="xerS"
                     /locus_tag="VIB18_001384"
     CDS             complement(9402..10472)
                     /gene="xerS"
                     /locus_tag="VIB18_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEQ8766386.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGAPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT         3212 a         2089 c         2100 g         3153 t
ORIGIN      
        1 attgaaagcg ctcttagaaa gaacacaaaa aagccatctc aaaaaagatt ggtggtatat
       61 aataaactta ctagttccct aaataggtaa atgtgaaaaa gaggtagctc atgcagtttt
      121 tacaaaaatg gtttaaacac tctaaaaaag agaagttgaa agaatcctcg ccccttagta
      181 cagaaataga accttctgaa aactgggaaa agattcccgc ttatattcct gcagacaaaa
      241 gcgattacaa aaaggttact ttaattacca gtgctattgc tgctggcgat agacctaata
      301 gtcaattcaa ggttaaacgc attctcaagc gcaatcctga ggcaatcact gtttctttaa
      361 ttgcttcaag tatcgctgca ggtgtttacc cagaaagtca gtttcgggtg acatccatct
      421 attgcaaaag gtagtcggtg aacgatactt tagacgaact catgacacaa taacatatag
      481 gagaaaaatg atgttacgaa aatttaaaat taccattgac ggtaaagaat atcttgtaga
      541 aatggaagaa atcggtgctc ctgcccaagc agctgccccc gctcaaccaa tatccactcc
      601 agtacctgtc cctactgaag caagcccaca agcggaggaa gcgcaagcac cacagccagt
      661 agctgcagcg ggagcggatg ccattccatc accaatgcct ggaaccatct taaaagtctt
      721 agtagcagtg ggagaccaag taactgaaaa tcagccacta ttgattttag aagccatgaa
      781 gatggaaaat gagattgtgg cctcatcagc aggaaccatt acagctatcc acgtcggtca
      841 aggtcaagtg gtcaatcctg gtgatggtct cattacaatt ggttaatagt actataacta
      901 gaataaatag acagaaaagg aagtgaattt gtggacactt taatcgcagg aataacctcc
      961 atcaccattc ctcaaattgt tatgatggtc atcggtgccc tcttaatgta tctaggaatt
     1021 aaaaaagaat acgaaccaac cttacttgtc cccatgggac ttggaaccat tctcgttaac
     1081 ttccctggtt caggagtttt aacccaagtg gttaacggag tcgagcaaga aggggttttt
     1141 gaggctctct tcaattttgg gattggaaca gaacttttcc cactgttgat tttcattggt
     1201 ataggagcca tgattgactt tggtcccttg cttcaaaacc cattcatgct cttgtttggt
     1261 gctgcagctc aattcggaat tttctttgtt gttgttgttg ctgtactggc tggctttgac
     1321 attaaagaag cagcttcaat cggcattatc ggagcagcag acggaccgac ttctatcttt
     1381 gttgccaacc aactggccaa ggatttactg ggtccaatta cggttgcagc ctattcttac
     1441 atggctctgg ttccgattat tcaaccattt gccattaaat tagtgacaac gaaaaaagag
     1501 cgccgtatcc gtatgactta caaagctgag aatgtatctc aaatgactaa aatcttattc
     1561 ccaatcatca ttaccttagt agcagggttc atcgccccaa tttctctacc tttagttggc
     1621 tttttgatgt tcggtaactt attacgtgag tgtggtgtgc tcgatcgcct gtcacaaact
     1681 gctcaaaatg aattggtaaa cattattagt atcttgcttg gattgaccat ctctattaaa
     1741 atgcaggcag acctgttctt aaatgtacag acactcttaa tcatcgtctt tggtttactt
     1801 gcttttatca tggattctat cggtggggtc atgtttgcca aatttctcaa tctcttccga
     1861 aaagagaaga ttaatccaat gattggcgct gcgggtattt cagcttttcc aatgtcaagt
     1921 cgtgtcattc aaaaaatggc aacagatgaa gacccgcaaa actttatcct catgtatgct
     1981 gtaggtgcca atgtctctgg ccaaatcgcc tctgttatcg caggtggttt gttgctagct
     2041 tactttagct aagaaaggaa ggaaacctta tgacaattaa tatggaccat ttgattagtt
     2101 cctttgagct aatggcgctt ggtatggcag gtgtctttat cgtgttaggc attctctatc
     2161 ttgtcgcaga gatcctgatc aaacttttcc cagttagtaa ataacaatat catttaagaa
     2221 aatcaaggag gtaaacgcaa tggatattaa acaaactgcc gttgctggtt cacttgaatc
     2281 aagtgaccta atgattacag tatcccctaa tgacgagaaa actattacaa taaccctaga
     2341 cagtagtgtt gaaaaacaat ttggcaatca cattcgtcaa ctcattcatc aaaccctagt
     2401 gaatttgaag gtgacggctg ctaaagtaga ggctgttgat aaaggtgcat tagattgcac
     2461 cattcaagcg agaaccatcg cagctgttca tcgcgctgct ggtattgacc aatacgattg
     2521 gaaggagatt gactcatgga acgtttaaga agaacaatga tgtttgtgcc tggtgccaat
     2581 gcagccatgc ttcgagatgc tcctttattt ggcgctgatt caatcatgtt tgacttggaa
     2641 gattctgttt cactcaaaga aaaagacacc tctagagctc tcgttcattt tgcgcttaaa
     2701 acttttgatt attcaagcgt tgaaacggtt gttcgtgtga atggtcttga ttcttgtggg
     2761 gttttagaca tcgaagctgt tgttttggca ggtgtcaacg tgattcgtct tccaaaaaca
     2821 gagactgccc aagatattgt tgatgtggag gctgttattg aacgtgtcga acgcgaaaac
     2881 ggcattgaag ttggtcgcac acgcatgatg gcagccattg aatcagccga aggtgtccta
     2941 aatgctcgtg agattgccaa agcttctaag cgcttgattg gtattgctct tggagcagaa
     3001 gactatgtca caaatatgaa aacgcgtcgt tacccagatg gtcaagaatt attctttgct
     3061 cgtagcatga ttttacacgc tgctcgtgct gctggaattg ctgccattga tactgtttat
     3121 tctgatgtca ataataccga agggttccaa aacgaagttc gcatgatcaa acagttagga
     3181 tttgatggta aatcggtcat caaccctcgc caaattcctc tggtcaatga gatttatacc
     3241 ccaacaaaaa aagaaattga ccatgccaaa caagtcatct gggcaattcg tgaagctgaa
     3301 agcaaaggct ctggcgttat ttccttaaat ggaaaaatgg ttgataaacc aatcgttgaa
     3361 cgtgcagaac gtgtgattgc cctagcaaca gcagcaggtg ttttatctga ggaggatatt
     3421 taaagatggt aacaaataaa ctcggtagag atattcctca accctacgcc gaccaatacg
     3481 gtgtctttga aggagaactc gtaaatatca aacagtatga cgaatcaagt cgccgtatta
     3541 aaccagttaa gcctggagat tctaaattac taggatctgt tcgtgaagcg attgaaaaaa
     3601 caggtttaac agatggcatg accatttctt tccaccacca tttccgtgaa ggggatttca
     3661 ttatgaatat ggtcttggag gaaattgcca aaatgggcat taaaaacctg tctattgccc
     3721 caagttccat cgctaatgta catgagcctt tgattgatca catcaaaaat ggcgtggtca
     3781 ctaacatcac ttcatctggt cttcgtgaca aagtaggggc agccatctca gaaggactaa
     3841 tggaaaatcc tgtggttatt cgctcccatg gtggtcgcgc tcgtgccatt gctagtgggg
     3901 atatccatat tgatgttgcc tttctgggcg ccccaagttc agatgcttac ggaaatgtta
     3961 atgggacaaa agggaaagca acctgtggtt ctttgggcta tgccatgatt gatgccaaat
     4021 atgcggatca ggtggttatc ttgacagata atttggttcc ttatcctaat accccaatca
     4081 gcattcctca aacagatgtt gactatgtgg taacagtgga tgctatcgga gatcctcaag
     4141 gaatcgccaa aggggcaact cgttttacga aaaatcctaa agaactctta attgcagaat
     4201 acgccgctaa agtaatcacc aactctcctt attttaaaga aggattttct ttccaaactg
     4261 gaacaggtgg cgcttctttg gcagtaaccc gtttcatgcg tgaagctatg attaaagaaa
     4321 atatcaaagc tagctttgct cttggtggta ttaccaatgc tatggtggag ttgctcgaag
     4381 aaggactggt tgaaaaaatt cttgatgtcc aagactttga tcacccatca gctgtttctc
     4441 ttggtaagca tgctgaacat tatgaaattg atgccaacat gtatgcctca cctttgagca
     4501 agggtgctgt tatcaatcaa ttagacactt gtattttatc agcccttgaa gttgatacta
     4561 acttcaatgt taatgtgatg acaggatctg acggcgtgat tcgtggcgct tctggaggac
     4621 actgcgacac tgcctttgcg gctaagatga gtttggttat ttcaccactt atccgcggac
     4681 gcatcccaac ttttgtagat gaggttaata cggtcattac accaggaaca agtgtcgatg
     4741 tggtcgtcac agaagtggga attgccatta acccaaatcg tcaagactta gtagaccatt
     4801 tcaaatccct caatgtgcca caatttagta ttgaggagct aaaagagaag gcttacgcta
     4861 tcgttggcac acctgagcgt attcaatatg gtgataaggt tgttgctctt attgaatacc
     4921 gtgatggtag cctcatggat gtggtttaca atgtgtaaag acacttattt ttcaggcgaa
     4981 gctatccaac ttagtgatat gttaagagcc cgcgaagaaa gagctctgcg tcagctgcat
     5041 ttattaaagg agtacccaga aggtagctta ttatcggtca ccatgaatat ccctggacca
     5101 attaaaacct ctcctaaact tcttgaagct tttgatatag tgattaaggc cattcaaact
     5161 gccttagctg acgataagat ttgttaccag ttgcgattac tgcctacaac gggttatgag
     5221 tattacctca tcacaagtct acctagccgc gacctgaagt taaaaatgat agccttagag
     5281 acagagttgc caataggtcg tctcatggat ttagatgtct tggtcttgca aaatgatctg
     5341 cctcattcaa ttagcagaac cgtattagga ggctccccta ggcaatgttt tatctgttct
     5401 aaagaggcca aagtctgcgg tcgcctacgt aagcacagtg tcgaggagat gcagactgct
     5461 atttcaaaat tactccattc atttttcaat aaagacaacc aatcatcgtc atcagataag
     5521 acaggttgat gaggagaaca attatgacga aaatccgtat aacggaaaca gttttacgtg
     5581 atggtcaaca aagtcagatt gccacacgta tgacaaccaa ggaaatgatt cctattctcg
     5641 aaacgctaga caatgctggt tatcatgccc ttgaaatgtg gggaggagca acctttgatt
     5701 cctgcctacg ctttttaaat gaagaccctt gggaacggct aagagccatc cgtaaagcag
     5761 tgaaaaagac taaacttcag atgctcttac gcggacaaaa ccttcttgga tatcgcaatt
     5821 atgctgacga tgtggtcaga tccttcgttc aaaaatccat tgaaaacggg attgatattg
     5881 tccgtatctt cgatgcttta aatgaccctc gcaacttgca aacagctgtt tcagcgacta
     5941 aaaaatttgg agggcatgct caagttgcca tttcttacac gacaagtccg gtacatacca
     6001 ttgattactt tgttgaattg gcgaaagctt accaagctat cggagcggac tccatttgta
     6061 tcaaagacat ggctggtgtc ttaactcctg aaataggtta ccaattggtc aaatgtatca
     6121 aggagaatac aactatccct cttgaggttc atacccatgc taccagtggt atttcagaaa
     6181 tgacttactt aaaagtagca gaagcaggag ctgatattat tgatacggcg atttcctctt
     6241 tttcaggggg aaccagtcag cctgccacag agtcaatggc gattgccttg acggatttag
     6301 gctttgacac aggcttggat atgcaagagg tggccaaagt tgcagaatat ttcaacacta
     6361 ttcgtgacca ctatcgagaa gtagggattt taaatcctaa agtcaaagat actgagccaa
     6421 aaacattgat ttaccaagtt ccaggtggca tgctatcaaa cctattgagc caattaaccg
     6481 agcaaggcct agctgataaa tacgaagaag tcttagcaga agtacctaaa gtaagggccg
     6541 atcttggata tccaccactt gtaacgccat tatcacaaat ggttggcaca caggccttga
     6601 tgaatatcat ctcaggggaa cgctacaagg tagttccaaa tgaaatcaaa gactatgttc
     6661 gagggctata cggtcaatca ccagcgccat tagcagaagg tattaaagag aaaatcattg
     6721 gtgacgaagc agttattact tgcagaccag ccgacctaat cgagcctcaa atgatttatc
     6781 tacgtgacga gattgctcca tacgctcgtt cagaagaaga cgtgttaagc tatgcgagtt
     6841 tcccacagca agccagagat ttcttgggac gccgtgaaga tcctttctat gatgttccgg
     6901 ttcaagaagt tactgtacaa ctggacattc aagactaaca gggaatgact aatcctctta
     6961 accattaatc tccttggtga aacgcatttg ctgtaagaac aataccaaaa acctacctga
     7021 ttttgataat cagataggtt ttttatctta gtaatgtttg acagatgaag tggcttgtag
     7081 ctttttaata atgggttggg cttctagcga acaaaaataa tctaaagacg ttttgggaag
     7141 gagttttgcc agaagttccc aatcattatc tttcaatgcc tgcctagccg ttgaggcact
     7201 gataggatct tgctgctgat tgatagcttt ccttggcaaa atatctagga ggataccagc
     7261 ttgctgcaac tgctctgcca taatttcatt gtaaatagca gttactcggc tggttggctc
     7321 ttctccaacg tatctttttg taatctgtaa ggtttgagca atctttagaa aaatagcggt
     7381 atccagcaaa gcttggctct taatcacgtc attgtcttct ttttggaaat aggctgggaa
     7441 agtcgcttgg ctaatcaaat aaggacctgt ttcatgatat atgacattat caagatgagc
     7501 tagaccttct tgaatcaacc tctttctcac cgaaaaagga attagactgc ggtcttcact
     7561 gaccataaac agatgaaccc aatcattttc tcttgcagct ttctctacta aaaattgatg
     7621 ccctaaggta aaggggttag cattgataac aatagcagcg actttaccag gtgtttgctc
     7681 aggcttatta agtgtcatca gataatcttg aaaaccagtt tttttatttt ccaagaaact
     7741 gatgtgattg tcgatatgga caatttcagt aaaaccaaga tctttgaaaa aagcagcaga
     7801 agaggtcttc gtataaacaa aaagatgata gttgccaagg gcatattctt catcaatgag
     7861 atgactcaca atcctattaa gaagtccttc accttgatag acactggata cgcaaagaca
     7921 gcgcaagcta tttccaaagt aagaaccggt agcaatcaca tcattttgcg cattcatgat
     7981 ggcacaagta taatctaaat gagcatccaa acgaatacct tcttgatgaa gcaggttctt
     8041 tacactagcc attgtcgttt tatctgaagg aaagactttt gaaatagtgt agtaaggcat
     8101 ttcttctcct tatctttaat tttattgaat cataacataa cttagtacca aaacaggctg
     8161 atctatctaa aggcaactct gttttttatc aacgccattt tttaaaagga aatcgaatgt
     8221 gtttgacaga ctcaaaagta tcagcgattt tttgattgcg ttccacagtc cgcaagtttt
     8281 cttggtctaa taagtcttga cttttttcca aaacatcaac agtaatgtag tagagtttga
     8341 tcaggcttcc tatcttatat ttaccagatt ttggagacat agcaaccact tcattgagat
     8401 tactatgaag ccatttttta tgaggcttag caggtatagt ggctactaca aagccaagtt
     8461 gttccaaatg agtttgtgcc tgatcaacag gaagattaat cacatcatct atcgtgcgta
     8521 gttgcatctc tttttcatgt ttttgttcca tacgtttttc gataattggt cgactgttat
     8581 caatcgtttt tccaataatt tcagtagtgt caggaacaat tgacatcagt ttcccaacta
     8641 ctcctagagc ttttcttatt ctctttggca tcttttatct cctcaagtcg tttcttttta
     8701 ttataacaaa atgtctaaaa atagtatgcg ataaaccttg ttctaaaagg ttaaatagat
     8761 caattcaagg aaaaaatagg aggggatccg acaaaaaaac acaaagattc taaaaaagtc
     8821 aagctatttt agtttagcct ttgtcaatcg tatcagttca aatagaaaat acaagttttg
     8881 acaagaattt atttatgtaa caaactgtgt ttttgattct tcagtctatc tagcgataat
     8941 gttatctgat tcttgttttc aaccaattga tgttaaagaa gctgtcttca tgattatcta
     9001 atattccttc aattttagct ttatattact ctaagttatc agtaatgaca ttaagtagtt
     9061 taacaagaat aatcctaaaa gctactttac aaaacaacgt attatcatac taaataaaag
     9121 tactgacata ctaaaaacag gcttatctca tctttttgat gagaacccta ctagatttaa
     9181 tctataaaca tcacaaaaaa gtcattcaaa gaagggacaa agttagcagt aatattcctt
     9241 tttctaagtg gcttgagtag tttggaaaac ggcctgacac caaactgtca cggttaatag
     9301 tagctatcta ttaaagttaa ttttgaagct atttttacct ttaatgttac ataaaaacaa
     9361 ttatgtaaca ttaaaggtta tctaaaaaca attatgtaac attaaaggtt atctaaagca
     9421 tttttttgct catcattgac aatatgggta taaagatccg tgacttgagt agaggaatgg
     9481 cctaattgat gactaactaa cacctgagat ttagtagcat catatagtct tgtcgctagc
     9541 gtatgacgca atttgtgagg agtcacacga attttaaaat cctcagagta cttgccaacc
     9601 atcttttcta tactagaagc atccattcga tttggagcgc cacggtattc tgttaaaaag
     9661 aaagcaagat cctgtttttc agccttgtaa cgtctctgac gaacagctag ataagactcc
     9721 aaataacctt tcgcaaaacc tgctacattg actgaatcac gttttccgcc tttgcgaata
     9781 acttcgataa tcatcatatt tagattgaca tcttttaaat caagattcac tgcttcagac
     9841 aaacgaacac cagaagcaag tagtagagca ataatagcca aatccctctc cttattttta
     9901 cggaaagaag atttggcacg attagacaat ttttgctcat attccttatc cacataatcc
     9961 aagaaagcta gagtttcatc acctaaaaac agtttctgct taatattttc tgctctggaa
    10021 gccagggttt cttttttctt ttttgttgac acttttttca taacattccg ataaaaataa
    10081 ggctcccctt ggtcattttc aacctcttca gtcaagtact tgtaaaggct tgataaggca
    10141 gacaaggtcc gattaatagt ggtttgagaa agcccctctt tggtggaata ggtgttgaga
    10201 gaaggtcgtt cccgcaaata aagtacaaag gcctctaaat ccttcttggt aaggtgctca
    10261 agcgtgctca agtcaatatc agcaatcttt ggcgcctgcg ttaaatcagc atccatcagc
    10321 caatcaaaaa agcgtttgta ttcttttaaa tactcatata aggtggtaaa gctgtatgga
    10381 acagctaatt tggattggta ataatctaaa acataccaag gcatgatggc cttgtaggtt
    10441 tcaatttttt ctagtaataa ttcgcgtctc atatcatcat aattccttaa caataacaat
    10501 tttttcaaaa atgaattttc gcaaattgtc tcatgtattt tatgccattc attc
//
LOCUS       DAUGSW010000040        10020 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUGSW010000040 DAUGSW010000000
VERSION     DAUGSW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10020
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.040"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            4..1140
                     /gene="dnaN"
                     /locus_tag="VIB18_001385"
     CDS             4..1140
                     /gene="dnaN"
                     /locus_tag="VIB18_001385"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ8766387.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            1216..1407
                     /locus_tag="VIB18_001386"
     CDS             1216..1407
                     /locus_tag="VIB18_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEQ8766388.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVL"
     gene            1743..2858
                     /gene="ychF"
                     /locus_tag="VIB18_001387"
     CDS             1743..2858
                     /gene="ychF"
                     /locus_tag="VIB18_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEQ8766389.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            2928..3497
                     /locus_tag="VIB18_001388"
     CDS             2928..3497
                     /locus_tag="VIB18_001388"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEQ8766390.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            3500..7003
                     /gene="mfd"
                     /locus_tag="VIB18_001389"
     CDS             3500..7003
                     /gene="mfd"
                     /locus_tag="VIB18_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEQ8766391.1"
                     /translation="MDILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSHGVLIVSLSGLRTLLPNPDVFTKSQIQLTIGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GIFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYKRLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQISSLSKYVSADGKEPKVNKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYISDERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            7165..7437
                     /locus_tag="VIB18_001390"
     CDS             7165..7437
                     /locus_tag="VIB18_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEQ8766392.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            7424..7795
                     /locus_tag="VIB18_001391"
     CDS             7424..7795
                     /locus_tag="VIB18_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEQ8766393.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKRTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            7930..9216
                     /locus_tag="VIB18_001392"
     CDS             7930..9216
                     /locus_tag="VIB18_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEQ8766394.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPVGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            9213..>10020
                     /gene="tilS"
                     /locus_tag="VIB18_001393"
     CDS             9213..>10020
                     /gene="tilS"
                     /locus_tag="VIB18_001393"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8766395.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLTIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTKL"
BASE COUNT         3535 a         1502 c         1833 g         3150 t
ORIGIN      
        1 ctcatgattc aattttcaat taatcgcaca ttatttattc atgctttaaa tgcaactaaa
       61 cgtgctatta gcactaaaaa tgccattcct attctttcat caataaaaat tgaagtcact
      121 tctacaggag taactttaac agggtctaac ggtcaaatat caattgaaaa cactattcct
      181 gtaagtaatg aaaatgctgg tttgctaatt acctctccag gagctatttt attagaagct
      241 agttttttta ttaatattat ttcaagtttg ccagatatta gtataaatgt taaagaaatt
      301 gaacaacacc aagttgtttt aaccagtggt aaatcagaga ttaccttaaa aggaaaagat
      361 gttgaccagt atcctcgtct acaagaagta tcaaccgaaa atcctttgat tttaaaaaca
      421 aaattattga agtctattat tgctgaaaca gcttttgcag ccagtttaca agaaagtcgt
      481 cctattttaa caggagttca tattgtatta agcaatcata aagattttaa agcagtagcg
      541 actgactctc atcgtatgag ccaacgttta atcactttgg acaatacttc agcagatttt
      601 gatgtggtta ttccaagtaa atctttgaga gaattttcag cagtatttac agatgatatt
      661 gagaccgttg aggtattttt ctcaccaagc caaatcttgt tcagaagtga acacatttct
      721 ttttatacac gcctcttaga aggaaattat cccgatacag accgtttatt aatgacagaa
      781 tttgagacgg aggttgtttt caatacccaa tcccttcgcc acgctatgga acgtgccttc
      841 ttgatttcta atgctactca aaatggtact gttaagcttg agattactca aaatcatatt
      901 tcagctcatg ttaactcacc tgaggttggt aaggtaaacg aggatttaga tattgttagt
      961 cagtctggta gtgatttaac tatcagcttc aatccaactt accttattga gtctttaaaa
     1021 gctattaaaa gtgaaacagt aaaaattcat ttcttatcac cagttcgacc attcacccta
     1081 acaccaggcg atgaggaaga aagttttatc caattaatta caccagtacg aacaaactaa
     1141 gtaagaaaaa gctccctttt aggagttttt tttgttatta taaatattaa cgataatata
     1201 agtggagaaa agggaatgta tcaaattgga tcatttgttg aaatgaaaaa acctcatgct
     1261 tgtgtaatta aagaaactgg taaaaaggct aatcaatgga aggtactgag agtaggagct
     1321 gatattaaaa ttcagtgtac taactgtcag catgtgatta tgatgagtcg ttatgatttt
     1381 gagcgaaaat taaaaaaagt actgtaacca tgaaagtcct tttaaataaa taattctagc
     1441 tatatttgca accaatactt tcctaaaaaa ttgctagtat gccgttggaa aatcagctat
     1501 tctaatgtta ttgaaagaag aaaggtggcc attgacaatg acgaaagttg tagcacagtt
     1561 acttagtttc tcggcaaact atatcaaaat gagaataata caccaaactt tgataattta
     1621 aatgaaggtg aaagagtggc ataatgataa gcaaatctga aattttcttc ttattcatac
     1681 cgctttttct tctatttttt ggtataataa tcttgattga aatttgaatg gagattcgct
     1741 aaatggcttt aacagcaggt attgtaggct taccaaatgt tggtaaatca accttattta
     1801 acgcaattac aaaagcagga gcagaagctg ctaattatcc ttttgcgact attgatccca
     1861 atgttggtat ggtagaggtt ccagatgagc gtctgcaaaa attgacagaa ttgattacac
     1921 ctaaaaaaac agttccgaca acctttgaat ttactgatat tgcaggtatt gttaaaggtg
     1981 cttctagagg ggaaggtcta ggaaataaat ttttagctaa tattcgtgaa gtcgatgcta
     2041 ttgttcatgt ggtacgtgct tttgatgatg aaaatgtcat gcgtgaacaa ggtcgtgagg
     2101 atgctttcgt tgatcctata gcagatattg acactattaa tcttgaatta atcttagctg
     2161 atttagagtc aatcaataaa cgttatgcgc gtgttgaaaa aatggcacga actcaaaaag
     2221 ataaagaatc agtagcagag ttcaatgttt tgcaaaagat taaacctgtt ttggaagatg
     2281 ggaaatcagc taggacaatt gagtttacag aagatgaagc aaaagttgtt aaaggtctct
     2341 ttttattaac aactaaacct gttttatatg tagctaatgt cgatgaagat aaagttgcta
     2401 atccagatgg tattgattat gtcaaacaaa ttcgtgactt tgcagctact gaaaatgctg
     2461 aagtagttgt tatctcagcg cgtgcagaag aagaaatttc agagcttgac gatgaggata
     2521 aagaagaatt tttggaagct atcggtctta ctgaatcagg cgttgataaa ttaaccagag
     2581 cagcttatca tctcttaggc cttggaacct attttacagc aggtgaaaaa gaggttcgtg
     2641 cttggacgtt taagcgtggt ataaaagctc cacaagctgc tggtattatc cattcagatt
     2701 ttgaaagagg ttttattcgt gcagtaacca tgtcttatga tgatctaatg acctacggtt
     2761 cagaaaaagc cgtcaaagaa gctggacgct tgcgtgaaga aggaaaagaa tatgttgtcc
     2821 aagatgggga catcatggaa ttcagattta atgtgtaatt atattaaaac aataccagaa
     2881 ggttggaaga acattccagc ccttttggca ttttagaaag agaaaatatg gtaaaaatga
     2941 ttgttggtct gggaaatcca ggctctaaat atgaaaaaac aaagcacaat attggtttta
     3001 tggctattga caatattgtc aagaaccttg acgttacctt tacagatgat aaaaatttta
     3061 aagcacagat aggaagtact tttattaatc atgaaaaagt ttactttgtg aaacctacta
     3121 cttttatgaa taatagcggc atagcagtaa aagcattact aacctactat aatattgaca
     3181 taacagattt aattgttatc tatgatgatt tagacatgga agtcagtaaa ttacgtttac
     3241 gtagtaaggg ttcagcagga ggacataatg gcattaagtc aatcattgcc cacattggaa
     3301 ctcaggaatt taaccgaatc aaagttggta ttggacgacc tttaaaaggt atgactgtta
     3361 ttaaccatgt gatgggccaa ttcaataccg aagataatat tgctatttcg ttaactcttg
     3421 acagagttgt caatgctgtc aagttttatt tacaagaaaa tgattttgaa aaaacaatgc
     3481 agaaatttaa tggataatca tggatatttt agaattattt agtcagaata agaaagtcca
     3541 atcctggcac tctggattaa ccaccttagg aagacaactg gtaatggggt tatcgggttc
     3601 aagtaaagca ttggctatag cttccgctta tttagatgat caaaaaaaaa tagttgtggt
     3661 tacatcaact caaaatgagg ttgaaaaatt agccagcgat ttatctagtt tacttgatga
     3721 agaacttgtt ttccaatttt ttgcagacga tgtggctgca gcggaattta tctttgcgtc
     3781 aatggataaa gctctatcaa gaatagaaac cctgcaattt ttaaggaatc ctaaatctca
     3841 tggcgtttta attgttagtt tatcaggctt aagaacttta ttgccaaacc cagatgtttt
     3901 tacaaagagt cagattcaac taacaattgg agaagattat gatagtgata ctcttactaa
     3961 acaactgatg acaattggct atcagaaggt ctcacaggtt attagtccag gagaatttag
     4021 ccgtcgaggg gatattttag atatctatga gattacacaa gaattgcctt atcgattgga
     4081 attttttggc gatgatattg atagtattag gcaatttcat ccagaaactc aaaaatcttt
     4141 tgaacaacta gaaggtattt ttattaatcc agcaagtgat cttatttttg aggctagtga
     4201 ttttcaacgt ggcattgagc aattagaaaa ggctctacaa acagcacaag atgataaaaa
     4261 atcttattta gaagatgtat tagctgtttc aaaaaacggt tttaaacata aggatatccg
     4321 taaatttcaa tcattatttt atgaaaaaga gtggtcatta ttagattata ttcctaaggg
     4381 aacgccaatc ttttttgatg attttcaaaa actagttgat aaaaatgcaa gatttgattt
     4441 agagattgct aatctcttga cagaagattt acagcaagga aaggctcttt ccaatcttaa
     4501 ctactttgca gataattatc gagagcttag gcactataag ccagcgacct tcttttcaaa
     4561 ttttcataag ggacttggaa atatcaaatt tgatcagatg catcagctaa ctcagtatgc
     4621 catgcaggaa ttttttaatc aatttccttt gttgattgat gagattaaac gatatcaaaa
     4681 aaatcaaaca acggttattg tacaggtaga gtctcagtat gcttacaaac gacttgaaaa
     4741 atcttttcaa gattaccaat ttcgccttcc tttagtgagt gctaatcaaa ttgtttcacg
     4801 tgaatcacaa attgtaattg gagctatctc cagtggtttt tattttgctg atgaaaagtt
     4861 agcgttaatc acagagcatg aaatttatca taaaaagatc aaacgacgcg ctagacgatc
     4921 taatattagc aatgctgagc gtttgaaaga ttacaatgag ttagcagtag gtgattacgt
     4981 ggttcataat gtccatggta tcggtcgctt tcttggaatt gaaacgattc agattcaggg
     5041 aatccatcga gattacgtta ctattcaata tcaaaattca gaccgtattt ctcttccaat
     5101 tgaccaaatt agtagcttat caaaatacgt ttctgctgat ggaaaagaac ccaaagtcaa
     5161 caaactgaat gacggtcgtt ttcaaaagac aaagcaaaag gtcgctagac aagtagagga
     5221 tattgctgat gaccttctaa aattatatgc tgaaagaagt cagcaaaaag gattttcatt
     5281 ttcaccagat gatgacttgc agcgcgcttt tgatgatgat tttgcttttg tagaaacaga
     5341 agatcaactt aggtctataa aggaaattaa agctgatatg gagagcatgc agcctatgga
     5401 tcgtctttta gtaggcgatg taggatttgg taagacagaa gtagctatga gggcagcctt
     5461 taaagcggtg aatgatcaca aacaagtagc tgtcttagtt ccaaccacag tcttggccca
     5521 gcagcattat gaaaacttca aagcacgctt tgaaaattac cctgttgagg ttgacgtctt
     5581 aagtcgtttc cgtagtaaaa aagagcaagc tgaaacacta gaacgtgtac gaaaaggtca
     5641 aattgacatt attatcggaa cccatcgact cctatcgaaa gatgtggtct tttctgattt
     5701 aggattgatt gtgattgatg aggaacaacg gtttggtgtt aagcataaag aaactttaaa
     5761 ggaattaaaa actaaggttg acgtcttaac cttaacagct actccgattc ctagaacctt
     5821 acacatgtct atgttaggta tccgagattt atcggttatt gagaccccac caaccaatcg
     5881 ttatcctgtt caaacctatg ttttggaaaa taatccaggt ctcgttagag aagctatcat
     5941 tcgtgaaatg gatcgtggag gacaaatttt ttacgtttac aataaagttg acactattga
     6001 aaagaaagtt gcagagctac aagaattagt cccagaagct tctataggtt ttgttcatgg
     6061 gcaaatgagt gaaattcaac ttgaaaatac cttgattgac tttataaatg gtgattatga
     6121 tgtccttgtg gctacaacaa tcatcgaaac aggagttgac atttctaatg taaacacttt
     6181 gtttattgag aatgctgatc atatgggatt gtcaacattg tatcaactga gggggcgcgt
     6241 cggaagaagt aatcgtattg cttatgctta cctgatgtat cgtcctgata aggtcctaac
     6301 agaggtttct gaaaagcgtt tagaggctat taaaggcttt actgaattag gttcaggctt
     6361 caagattgct atgcgagatt tgtctatacg aggagcaggt aatattttag gggcttctca
     6421 gagtggcttt attgattcgg tcggttttga aatgtattct cagttattgg aacaggctat
     6481 tgctagcaag caaggaaaaa cgactgttcg ccaaaaaggt aatactgaaa tcaatcttca
     6541 gattgacgcc tatttgccag atgattacat atcagatgag cgtcaaaaaa ttgacattta
     6601 caagcgtatt cgagaaattc aatcaagaga agattatctc aatttgcagg atgagctgat
     6661 agatcgtttt ggagagtatc ctgatcaagt tgcctatttg ttagagatag ctctgctaaa
     6721 acattatatg gacaatgcct ttgcggaatt agttgaacgc aaaaataatc aggtcattgt
     6781 tcgatttgaa gtaacttctt taacttattt cttgactcag gattatttcg aagccttatc
     6841 gaaaacccat cttaaagcta aaattagtga acatcagggg aaaatcgata tcgtctttga
     6901 cgttcgccat caaaaagatt atagaatttt agaagaattg atgttatttg gagaaaggct
     6961 tagtgagata aaaatcagaa aaaacaattc agtttttaaa taataatttg aaacaacttt
     7021 tagactgaat agtattaatg acaatggaac gaactagctc tttatacttt tgtcaaaaat
     7081 ctaagatctt tgctgcgaaa ttaggatctt ttctaccatt taaaaaataa aaatgataaa
     7141 atgaagagga ttgtaggaga aattatgaga ctagataaat atctaaaggt atcgcgcctt
     7201 attaaacgtc gttcagtagc aaaagaagtt gcggataagg gacgaattaa agttaatggg
     7261 atacttgcta aaagttcaac gaatataaaa ctaaatgatc acattgaaat tagttttgga
     7321 aataaattac tgacagtaag agtcattgaa ataaaagata gtacaaaaaa agaagatgct
     7381 cttaagatgt atgagataat cagtgaaaca aggataacat taaatgaaga agcctagtat
     7441 tgttcaatta aataaccatt atattaagaa agagaatctc aaaaaaaaat ttgaagaaga
     7501 agaatctcaa aaaagaaatc gttttatggg atggatcctt gtaagtatga tgtttttatt
     7561 tattttgcca acttataatc ttgtcaaaag ttatgttgat tttgaaaagc aaaatcaaca
     7621 ggtggttaaa ttaaaaaaag agtataatga attgtcaaag aggacaaaaa aagaaaaaca
     7681 attagcagaa cgactaaaag atgataattt tgtcaaaaaa tatgctaggg caaaatacta
     7741 tttatcgcgt gaaggagaaa tgatttatcc tattccagga ctattaccaa aatgatgatg
     7801 gacaatattg taaaaaaaat agaagcattt cttgcttttt ctgataaaaa attagcagag
     7861 ctgcaacagg aaaatcaaaa agttaaagaa gaaagtcagt atattcaaaa aaactagaaa
     7921 ggagtcaata tgagaaaatt attagcggct atgttaatga ctttttttct gactccttta
     7981 ccagtgatta gtacagaaaa aaaacttata ttttcaaaaa atgctgttta tcaattgaaa
     8041 caagatgtcg ttcaatcaac acaattctat aatcaactac cctctaatcc aaatctttat
     8101 caagaaacgt gtgcctataa agacagtgat ttaactctac cagtaggaag attaggtgta
     8161 aatcaaccat tacttattaa atcgcttgtg cttaacaaag aatctttacc ggtttttgag
     8221 ttagctgatg gtacctatgt tgaggctaat cgacaattga tttatgacga tattgtactt
     8281 aatcaagtag atatagatag ctatttttgg acacaaaaga aacttaggct ttattcagcc
     8341 ccttatgttt taggtacgca aacaattcct tcttcttttt catttgctca aaaagttcat
     8401 gccactcaaa tggcacaaac aaaccatgga acttattatc ttattgatga taagggctgg
     8461 gcatcacaag aagatctagt tcaatttgat aaccgcatgt taaaagtcca ggaaatgctc
     8521 ttacaaaaat ataataaccc aaattattca atttttgtaa agcaactcaa cacacaaaca
     8581 agtgctggta ttaatgctga taaaaaaatg tatgctgcaa gtatctcgaa gttagcacca
     8641 ctttatattg ttcaaaaaca attacaaaaa aagaaattag cagagaataa aactttgact
     8701 tatactaaag atgttaatca tttttatgga gactatgatc cattaggaag tggtaaaatt
     8761 agtaaaatag ctgataataa agattatcgt gttgaagacc tactgaaagc tgtagcacaa
     8821 caatcggata atgtagcaac taatatttta ggttattatc tatgtcatca gtatgataaa
     8881 gctttccgct cagagataaa agctttatca ggtatcgatt gggatatgga gcagcgctta
     8941 ttaacttctc gttcagctgc aaatatgatg gaagctattt atcatcaaaa aggccaaatt
     9001 atttcttacc tttcaaatac cgaatttgat caacaacgta tcacaaaaaa tattactgtt
     9061 ccagttgcac ataaaattgg tgatgcttat gattataaac atgacgttgc tattgtttac
     9121 ggtaatactc catttatttt gtctattttt acaaataaat caacctatga agatattacg
     9181 gctattgcag atgacgttta tggtatttta aaatgatgac ctatcaagaa atttttaatg
     9241 aaataaaaaa taaagcctac tttaaaaatc atagacatgt gttaatagcc gtatctggtg
     9301 gagtagattc aatgaattta ttgcactttt tgtacctgtt tcaagacaaa ttgacaattc
     9361 gtattggtat tgctcatgtt aatcacaaac aaagatcaga atcagattca gaagaagctt
     9421 atttaaagtg ttgggctaaa aaacatgaca tacctattta tgtttctaat tttgaaggaa
     9481 tattttcaga aaaagcagca cgtgattggc gctatgcttt ttttaagagt attatgttaa
     9541 aaaataacta ttcagcttta gtaacagctc accattcaga tgatcaagca gaaactattt
     9601 tgatgaggct aattagagga agccgattga ggcacttgtc gggtataaaa agcgtgcaac
     9661 catttgccaa tggtcaactt ataagacctt ttttaacttt ctcaaaaaag gacttgccag
     9721 aaatttttca ttttgaagat tcttcaaata gagaattatc atttttaaga aatagagtta
     9781 gaaataatta tttaccactg ttaaagcagg aaaatcctag gttcattcag ggattaaatc
     9841 aattagcact tgaaaatagc ttactttttc aagcttttaa ggagctaaca aatcatatta
     9901 ctaccactga tttaacagaa tttaatgagc aatctaagtc aattcaatac tttttgttac
     9961 aagattattt agaaggtttt ccagatttag atttaaaaaa atctcaattt actaaattat
//
LOCUS       DAUGSW010000041         9742 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUGSW010000041 DAUGSW010000000
VERSION     DAUGSW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9742
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.041"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            16..882
                     /locus_tag="VIB18_001394"
     CDS             16..882
                     /locus_tag="VIB18_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEQ8766396.1"
                     /translation="MKMKKKFFLLSLLALSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANSKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLKLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            893..1828
                     /gene="pstC"
                     /locus_tag="VIB18_001395"
     CDS             893..1828
                     /gene="pstC"
                     /locus_tag="VIB18_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEQ8766397.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRAIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAIIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1818..2705
                     /gene="pstA"
                     /locus_tag="VIB18_001396"
     CDS             1818..2705
                     /gene="pstA"
                     /locus_tag="VIB18_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEQ8766398.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            2721..3524
                     /gene="pstB"
                     /locus_tag="VIB18_001397"
     CDS             2721..3524
                     /gene="pstB"
                     /locus_tag="VIB18_001397"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766399.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            3537..4295
                     /gene="pstB"
                     /locus_tag="VIB18_001398"
     CDS             3537..4295
                     /gene="pstB"
                     /locus_tag="VIB18_001398"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766400.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            4363..5016
                     /gene="phoU"
                     /locus_tag="VIB18_001399"
     CDS             4363..5016
                     /gene="phoU"
                     /locus_tag="VIB18_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEQ8766401.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEISASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5221..7758
                     /locus_tag="VIB18_001400"
     CDS             5221..7758
                     /locus_tag="VIB18_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEQ8766402.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQSTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            8105..8779
                     /locus_tag="VIB18_001401"
     CDS             8105..8779
                     /locus_tag="VIB18_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8766403.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
     gene            8772..>9742
                     /locus_tag="VIB18_001402"
     CDS             8772..>9742
                     /locus_tag="VIB18_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8766404.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVN"
BASE COUNT         3019 a         1616 c         1981 g         3126 t
ORIGIN      
        1 aataggaaat aaataatgaa aatgaaaaaa aaattctttt tgttaagtct tttggcccta
       61 tcaactttct ttttatccgc atgttctagc tggattgata aaggtgagtc aataaccgct
      121 gtaggatcaa cagcactaca acccttagta gaagcagtag ctgatgaatt tggaagcagt
      181 aatctaggca agactgtcaa tgttcaaggt ggtggttcag gtacagggtt gtctcaagtt
      241 caatcaggag ctgtccaaat tggaaatagt gatgtctttg cagaagaaaa agatggtatt
      301 gatgcttcta aattagttga tcatcaagta gctgttgcag gacttgcagt tattgccaat
      361 tctaaagtca aggtttccaa tctcagtagt cagcagttgc aaaagatttt ttcaggagaa
      421 tataccaatt ggaaacaagt tggaggagaa gatcttgcga tttcagtgat caaccgagca
      481 gcaagttctg gctcacgagc aacctttgac agtgttatca tgaaaggggt caacgctaaa
      541 caaagtcaag agcaagactc caatgggatg gttaaatcga ttgtttcaca aacaccaggt
      601 gccatttctt acctttcctt tgcctacgtt gattcatctg ttaaatcttt gaaattaaat
      661 gggtttaagg caaatgctaa gaacgtggct acaaatgatt ggccaatctg gtcctacgaa
      721 cacatgtata ccaaagataa accaacaggg ttgaccaagg aatttcttga ttatatgttt
      781 tcagatgaag tacaacagaa cattgttaca catatgggat atatttcgat aaatgatatg
      841 gaagtggtca aatctcatga tggaaaagta acaaaaaggt aatggaggaa ttatggaaaa
      901 tcaggaattg gctaaaaaat tagcctcacc atcaaagaat tcaagacttg aaacctttgg
      961 ccgcaccatt acgtttttgt gtctggcttt gattgttttt atcgttgcga tgattctgat
     1021 cttcgttgct caaaaagggt tgtcaacctt ctttgttgac aaggttaatc tttttgattt
     1081 cttgtttgga aaggagtggc aaccaagtgt gaaaaatgcg gccggcattc cttatcttgg
     1141 tgctctgcca atgattacag gatccttttt ggttaccatt ttatctgcta ttattgccac
     1201 cccatttgcc attggcgcag ccgtttttat gactgaaatc tcacctaaat atggcgctaa
     1261 attattacag cctgcggttg agcttttggt tggaattcct tcggttgttt atgggtttat
     1321 cggtttgcaa gtgattgttc cttttatgcg cgctatcttt ggtggcacag gttttggaat
     1381 cctatctggg gtctgtgtct tgtttgttat gattttacca acagtgactt ttatgacaac
     1441 agacagtctg cgggcggtgc ctcgtcatta ccgcgaagcg tctatggcta tgggagcaac
     1501 ccgttggcaa accatttggc gtgttgttct taatgcagct cgtccaggta tttttactgc
     1561 cattattttc gggatggcga gagcttttgg tgaagcctta gccattcaaa tggttgtcgg
     1621 taactctgct gtaatgccaa gttcactaac gacaccagcc gcaaccttaa cgtctgtctt
     1681 gacaatgggt attggtaaca cggttatggg aacggtccaa aataatgtgc tttggtccct
     1741 tgccctagtc ttattattaa tgagtctggc cttcaattcc cttgtcaaat taatcacgaa
     1801 agaaagaaag agaaattatg aacgctaaaa aagtcgataa agtagcaact ggtactcttt
     1861 ataccattgc tggaattatt gtagctattt tagcttcctt aattctatat atccttgtcc
     1921 gtggcttgcc acacatcagc tggtcctttt taacaggaaa atcgtcttcg tacgaagctg
     1981 gtgggggaat tggtatccaa ttgtataatt ccttcttcct attgattgtt accttgatta
     2041 tttccattcc tttatcaact ggagcgggga tttacttggc tgaatatgcc aaaaaagggc
     2101 ctgttaccaa ctttattaga acctgtattg agattctgtc ttccctacca tctgtggttg
     2161 tagggctctt tggttacttg attttcgttg tgcagtttga atatggcttt tctattattt
     2221 caggggctct tgctttgacg gtctttaatc ttcctcaaat gacccgtaat gttgaagata
     2281 gtttactgca tgttcatcat acccaaagag aagcaggatt agctttaggc ctgtcacgct
     2341 gggaaacggt tttttatgtg gttatcccag aagctctccc gggaatggta acaggtattg
     2401 tcttagcttc aggtcgtatt tttggtgaag cggcagcgct tatctatact gctggtcaat
     2461 cagcaccagc tctggattgg tcaaattgga atccacttag tgttactagt ccaatctcta
     2521 ttttccgtca atctgagacc cttgctgttc atatttggaa agtcaatagc gaagggacaa
     2581 ttccagatgc tactcttgta tccgcaggaa gtgcagcagt gctattaatt tttatcctta
     2641 ttttcaactt ttcagctcgc tttattggga agaaacttca ttctaaaatg acagcggcca
     2701 aataaaatag tggagaaatc atgacagaat acaattggaa tgaacgtcat atcatcactt
     2761 ttcctgaaga aacgcttgct ctagctacca aggatttaca tgtttactat ggtgcgaaag
     2821 aagctatcaa agggattgat atgcagtttg aaaaacataa aataacagcc ttgattggtc
     2881 catctggttg tggcaaatca acttatcttc gtagtcttaa ccgcatgaac gataccattg
     2941 atattgctcg ggttacaggt gagattcttt atcagggcat tgatgttaat cgaaaagaca
     3001 tgaatgttta cgagattcgc aagcacttag gaatggtttt tcaaagaccc aatcctttcg
     3061 ctaaatccat ttataaaaac attacctttg cccatgaaag agctggtgtg aaagacaaaa
     3121 aagttttaga tgaaattgtt gagacttcac tgaaacaagc cgcgctttgg gatcaagtta
     3181 aagatgatct tcacaaatca gccttcactt tatcaggggg gcagcaacaa cgtttgtgta
     3241 ttgctagagc catttctgtc aaacctgata ttctattaat ggatgaacca gcctctgccc
     3301 ttgacccgat tgcaacgatg cagctggaag aaaccatgtt tgaattgaag aagaattaca
     3361 cgattattat tgtgacccac aatatgcaac aagcagctcg tgccagtgat tacactgcct
     3421 tcttctattt aggcaacctc attgaatatg ataagacacg taatattttc caaaatgcgc
     3481 aatgtcagtc aacaaacgac tacgtttcag ggcactttgg ttagaaaggc aatatgatga
     3541 cagaacctat tttacagatc agagaccttt ctgtttacta caatcaaaag aaaacgttaa
     3601 aagatgtctc tttggacctt tatccaaatg aaataacagc tttaattggt ccttctggat
     3661 ctgggaaatc aacgctcttg cgttctatca accgtatgaa tgatttgaat cctgaagtaa
     3721 ccattacagg ctctatcgtc tataacggac acaatattta tagtccaagg acagatacgg
     3781 ttgatctacg caaagaaatt ggtatggtat tccaacaacc caacccattt ccgatgtcta
     3841 tttatgagaa cgtggtttac ggccttcgct taaaaggtat cagagataaa tcaatcttag
     3901 accatgctgt tgaaagctct cttaaagggg cttccatttg gaatgaagtc aaagatcgtt
     3961 tacatgattc tgcggttggc ttatcaggcg gacagcaaca gagagtttgc atagctagag
     4021 ttcttgctac cagccccaga ataatccttt tagatgaacc tacctcagct cttgatccta
     4081 tctcagctgg gaaaattgaa gaaacattat tgttattaaa aaaagattat acactggcta
     4141 ttgtgacccg ctcaatgcag caagcctcac gtttatcaga tcgaacaggt tttttcttgg
     4201 agggtgactt acttgagtgt ggtcctacaa aagccatgtt tatgaatcct aagcgcaaag
     4261 aaaccgaaga ctatatttct ggtaaatttg gttgagaaag acgtatatgg ttgacccctc
     4321 tgtgttttta ttataatgac tagattgtag gaagaaaaaa tcatgttaag aacgaaattt
     4381 gaagaagaat tagataaatt gcataaccag ttttattcaa tgggaacgga agtattggca
     4441 caaatcaata aaactgttcg tgcctttgtt agtcatgatc gtgaattggc caaagaagtt
     4501 atcgaagaag atgacactat taataatttt gagacaaagc ttgaaaagaa atcgctggaa
     4561 attattgccc tacaacagcc agtttcgaat gatcttagaa tggttattac tgttttaaag
     4621 gcatcaagtg atattgaacg tatgggtgac catgctgctt cgattgccaa ggccactatt
     4681 cgtatgaaag gtgaggagcg tattccagtg gttgaagaac aaatcaacct tatgggaaaa
     4741 gctgtgaaac agatggtaga agaagccctt aatgcatata tcaatgctga cgatacaaaa
     4801 gcttatgaaa tctcagcttc tgatgagatt atcgatcaat atttccgtaa tatccaaacc
     4861 ttagctgttg aagaaattcg taagtctcca gatgctgtct ttgcaggaaa agaatatttt
     4921 caagtattaa tgtatttgga acgtattggt gactatgctc gcaacatttg tgaatggatt
     4981 gtttatctta aaactggaaa aattattgaa ttataagaaa ttatgctata atgagactgg
     5041 gaaacagctt gccagtccct ggttttatac gaaattgtgc aagttagaaa atgaactaac
     5101 aagaaaagtt ttctttgctg aatctgattt tgttaggtta acaaatatat gtagacagag
     5161 atgatactta ggtatcatct gttgatctat tatgatttgt tattagaatt aaggagttat
     5221 atgaagacag tagaacatct catcgaaaca tttgtgcctg aaaattataa catcttttta
     5281 gatattaatc gtcagactaa aacatttacg gggaatgttg cgattaatgg tgaagcttta
     5341 gataatcatg tggctttcca ccaaaaagat ttggacatta agtctatttt gctcgataat
     5401 gaagctgtta tttatcaagt ggataacgac aatgaagttg tgcgtgttga attacctgaa
     5461 acaggaatga tgacgcttgt cattgaattt tcaggtagca ttacagataa tatgacaggt
     5521 atttaccctt catattacac taaaaatggt gagaaaaaag aagtcatttc aactcagttt
     5581 gaaagccatt ttgcgcgtga agctttccca tgtatcgatg aaccacaagc aaaagctact
     5641 tttgatttaa gcttgacctt tgatcaagaa attggtgaga tagcgttatc gaatatgcca
     5701 gaagtcaata ttgaccgtcg cgaggaaact ggtctttgga catttgatac gacaccaaga
     5761 atgtcatctt acttgctagc gtttgcgcta ggagaacttc atggaaagac tgtagaaagc
     5821 aaaaaaggaa caactgttgg tgtgtatgcg acaacagcgc atcctcttag ctcgcttgat
     5881 ttttcattgg atattgcagt tcgtgttatc aacttttatg aagactattt tggagtacat
     5941 tacccaatcc cgcaatctct taatattgcg cttccagatt tttcatctgg tgctatggaa
     6001 aattggggtt taatcactta tcgtgaaatt tatttattag tagatgaaaa ttcgactgtt
     6061 caaagccgac aacaagttgc acttgtaatc gcccacgaga tagcacacca atggtttgga
     6121 aacttggtta caatgaaatg gtgggacgat ctgtggttaa atgagagttt tgccaacatg
     6181 atggaatatg tctctatcga ggctattgag ccgtcttgga aaataataga agatttccaa
     6241 acaggcggta ttcctcttgc tttaaaacgt gatgctactg atggtgttca atcagtgcat
     6301 gttgaagtca atcatccaga tgagataaat acattgtttg atcctgctat tgtctatgca
     6361 aaaggtagtc gtttgatgca tatgttacgc cgttttattg gtgatcgtga ttttgccatt
     6421 ggtttacatc actactttga aaaatatcaa tatcgaaata ctgtcgggcg tgatttatgg
     6481 aatattttat cagatacttc aggcaaagac gtagctgctt ttatggatgc ttggcttgaa
     6541 caaccaggtt atccagtttt aacagctcgc cttgaaaacg atcaattgat tttgagtcaa
     6601 aaacaatttt ttattggaaa aggtgaagaa aaaggtcgcc tttggccgat tcctttaaac
     6661 actaattggc atggccttcc tgaaactttg acagaggcag aaatggtcat tccaaacttt
     6721 agtcaattgg cagcagaaaa tgaaggagct ctacgtttca atattgataa tacagctcat
     6781 tacattacag attaccaagg atcattatta gatgccttag tcactgaact tgcccaactt
     6841 gataatactt ctgctttaca agttattcaa gaacgtcgtt tattggcaga tagtggcttg
     6901 atttcctatg ctgaattggt tgacttaatt gctcaattgg acgattctaa gtcttatatg
     6961 gtagcagaag cggttcagca agtggtctct ggtttgaaac gcttcattga tgaaggaagc
     7021 ttagcagaaa aatcctttaa tcgcttggta accaccatct atcaagaaga ctttaatcag
     7081 catggttttg agaaaaaagc tgacgaatca gatgaagatg agatggtacg tcaggttgcc
     7141 ttgggacgct tgtggctagc agaaaatcag acgattattg acggattgag aactattttt
     7201 gaagcatatc aaaacaatat tgcaagtatt ccagcagctg ttcgtcgctt ggttttagcc
     7261 aaccaaatga aatattttga aacagatagc ttggttgata tttattttga gacttatgta
     7321 gcaactactg ataataattt acgcagtgat ttaacggttg cttttagtca aacaaaacaa
     7381 tcaactacta ttagacgtat tcttgttagt ttaaaagata aagatattat taaacctcag
     7441 gatttatctt attggtacaa tgctttgctt ggacaaagct ttactcaaga tatcatttgg
     7501 gaatgggcta gagaaaattg ggattggatt aaatctgcac ttggtggaga tatgagcttt
     7561 gataaatttg ttatttatcc agcaagtaac tttaaaacac caaaacatct agcagaatat
     7621 aaatctttct ttgaacctaa gctagatgat atggctatta gccgtaatat taccatggga
     7681 attaatgaaa ttgaagcacg tgttgctttg atcactaaag aaaaagaagc agttattgca
     7741 gctctcagtc attactagac cataagcaaa agagttgggg ggactttcca gctctttttt
     7801 gtagtgagct agcttccttt cttagttccg tctataacta aatgattatc catagtttaa
     7861 ttcaaaagga gattgcactt taaagcgaag gctattagcc tcttaaatac ttttttacca
     7921 ggtggtgaat aagaacaatt ataaatgatt taaccattat gctttaaatg ccttaaagga
     7981 gtattaatat tttagtaaac cttaagcttt ttgtagtata gtctcgttag aaattgttat
     8041 cagaaatgag actaagttaa atgaagtgat agttacttta tttaagaaca attgaggtag
     8101 agacatgata aaaatattat tagtagaaga tgacttgagc ttatcaaatt ccatttttga
     8161 ttttttagat gattttgcag acgtcatgca agtttttgat ggcgatgaag gtttatacga
     8221 agcagaaagt ggtatttatg atttgatttt gttagacctt atgttgccgg agaaaaatgg
     8281 ctttcaagtc ttaaaagaat tgcgagaaaa agatattaaa attcctgtgt tgatcatgac
     8341 agctaaagag ggtttagatg ataaaggtca cggatttgaa ttaggtgctg atgattatct
     8401 gaccaagccg ttctatttag aagagttaaa aatgcgaatt caagcactgt taaaaagaac
     8461 agggaaattt gcagataaaa atattagttt tggcaattta gtggttgact tagctcgaaa
     8521 agaggtgaag gttgaaggga aagtagttga attacttggc aaagaatttg atttgttggt
     8581 gtatcttttg caaaatcaaa acgttatttt accaaagaca caaatttttg atcgtttatg
     8641 gggattcgat agtgatacta cgatttcggt tgttgaagtt tacatttcta aaataaggaa
     8701 aaaattaaaa ggtacccgtt ttgttaacag gcttcaaact ttaagaagcg tagggtatat
     8761 tctaaaaaac aatgaataaa ttaaaaaaag agattttatc agataactat aaccactttt
     8821 ttcatttttt tgcggttttt acaggtattt ttgtcattat gactattatt atcttacaga
     8881 ttatgcggtt tggcgtttat tcgtcagttg acagtagttt agtttctgtt agtaataatg
     8941 caagtagcta tgctaatcgt acgatggcta gaatatcttc tttttacttt gatactgaaa
     9001 ataacattat taaggcgctg cctgattcag atagttctaa gttattagga acgcctgcag
     9061 ctaatacaga tatcattttg tttagtgcta atggaacaat tttaaatgct tttgatgcgt
     9121 tttctaacta tcaaaatttt catttagata aacgccggtt ggggagtatt gaaaccacca
     9181 gtttaatgaa tttttatgga caagaagaaa aataccatac gataactgta agggttcata
     9241 tcaaaaatta tcctgcagtt gcctatatga tggcagtagt aaatgtggaa caattagacc
     9301 gcgctaatga acgttacgag cgcattatta ttatagttat gagtgttttt tggctaattt
     9361 ctattttagc aagtatttat ttagccaagt ggagcagaaa acctatttta gaaagctatg
     9421 aaaaacaaaa aatgtttgtt gaaaatgcta gtcatgaact aaggacccct ttggcggtct
     9481 tacagaatcg tctggaatcg ctttttcgta agcccaacga aacgatatta gaaaatagtg
     9541 agcatctcgc ttctagttta gacgaggttc gcaacatgcg catcttaaca actaatttat
     9601 taaatttagc aagacgagat gatggcatta atccacagtg gactcattta gatacagatt
     9661 tttttaatgc tatttttgag aattatgaac tagttgctaa agaatatgga aaaatatttt
     9721 attttcagaa ccaagtcaat ag
//
LOCUS       DAUGSW010000042         9141 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUGSW010000042 DAUGSW010000000
VERSION     DAUGSW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9141
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.042"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(110..1252)
                     /locus_tag="VIB18_001403"
     CDS             complement(110..1252)
                     /locus_tag="VIB18_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEQ8766405.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITSNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFYQKTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
     gene            1533..4511
                     /locus_tag="VIB18_001404"
     CDS             1533..4511
                     /locus_tag="VIB18_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEQ8766406.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTTSAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRHLTNTFRNSRWYGFTGTPIFMENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLNSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            4524..5699
                     /locus_tag="VIB18_001405"
     CDS             4524..5699
                     /locus_tag="VIB18_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8766407.1"
                     /translation="MTKSKQPQYRFDGFEGEWEEKELGDIVQITMGQSPSSQNYTTNP
                     SDYILVQGNADIKNGYVFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIGRG
                     VAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIPSLPEQEAIGE
                     LFQMVDQLIQLQDQKLATLKEQKQTFLRKMFPAQGQKVPEIRLQGFDGEWEEKKLGEI
                     SRMFSGGTPNVGIPEYYNGNIPFIRSAEINSDQTELSITDKGLSNSSAKLVEKNTLLY
                     ALYGATSGEVGLSRISGAINQAILAIIPEKKYSSLFIKNWLYKQKSSIIEKYLQGGQG
                     NLSGSIVKGLELYLPSLPEQEAIGDFFQTLDQQMSQIEDKLTELKALKQTLLNRLFV"
     gene            5712..7292
                     /locus_tag="VIB18_001406"
     CDS             5712..7292
                     /locus_tag="VIB18_001406"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEQ8766408.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLLAVCDNLEKHFNTFTEAQKIFEDAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLGQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(7839..8444)
                     /locus_tag="VIB18_001407"
     CDS             complement(7839..8444)
                     /locus_tag="VIB18_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8766409.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPHLKVVVLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(8425..>9141)
                     /locus_tag="VIB18_001408"
     CDS             complement(8425..>9141)
                     /locus_tag="VIB18_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766410.1"
                     /translation="DASTLFCLVVISCIFYYLENSKQNFDYENRRLNYFMKSEENMRV
                     EFSNYLHDDVLQNIIAIKNLLSLENSNITHGFIVNELNDLVSGIREEIDTYHPIVPAN
                     QTMKENIQSLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGD
                     GKDIRLSLTIQSDIIIIEESNQVVEKVHSISYGRGLKSFQETLAAFDGDLELQMDTKQ
                     FTIRILLPIDWKLCYEDFIN"
BASE COUNT         3060 a         1746 c         1557 g         2778 t
ORIGIN      
        1 aaatgtttct gtttttcata ctatgctaat gagttagctc gtacgtctcc ttcttcatag
       61 gttactttta accgccaaat gaatgctaca caatcgaaaa tagatgagtt tacttattaa
      121 actgggctat caatagcata aggttagctg ctaatatttt gatattggaa agtgttgttg
      181 ttttatctat cgctgcttct aaggaaattg gctgctgttg tattgaaaaa acagccaaaa
      241 agtcttctgc tgctagtcct gtctcaatct ttacagaacc acatagagca atcgttggaa
      301 cttgatattt tttagccatt cttgcaatcg caacaggtac cttgccagat tgtgattgtg
      361 tatccaggca tccttctcca gtaataacta aatcacagga ctgaagggaa ttatccagat
      421 ttagtagctc tgcaatcctg ctaaaaccac tagttaaggt gcctcctaat aggacaatgg
      481 cacctcctaa tcctccagct gctccacttc ctggtattgt ctgtaaatca atggtttttt
      541 ggtaaaaaac ttttttagca aagttacttg caatttgatc agtttcttca atttgactaa
      601 gactcccacc tttttgaggg ccaaagaccg cagcaaatcc ttgagggcca tgatatggat
      661 tggtcacatc agtcagccct aatagcgtaa caggtgatgc taaagtatca agataagatc
      721 ttcctgtcat gaaatcatag tttaaacttt ccaaaaaccc tttgccacca tcagaagtgc
      781 ctgttcctcc tagcatgatt tcgatttgag tagctccttt ttgaatggca tctttaactg
      841 ccaaacccaa accataggaa gtggcttgtg cataggttac tgaattggag gtgatcttat
      901 caataccaat aatactcgca gattcaataa aagcttgctt tgcgtgacga taataagcga
      961 ctttaatcgg acgtcttaat agatcaatgg tttttacttg atgccacctc cccgccacgg
     1021 tttgtgagag ggctgctaaa cttccttctc ctccatcagc gatagctctt gtttcaataa
     1081 ctaactgctt atcgacagaa agaagggctt gagctacact agtgttaagt tctggagacg
     1141 ttaccgatcc cttaaaagaa tctatggcta ccaaaatttt catatcttca ataaattcct
     1201 tttctgtata ttgtagcaga ttatcgtcct ttaaaaccct attaatagtc aagctagatc
     1261 tgtcttaagt tttttatcta ttttgagaac tcgacctttt tactagtgtt gtcttattac
     1321 tttcttcacc ttaaattatt gtcaagcaaa ctcaaaaata caagaacttt ctcgattgca
     1381 tttacatagt catagctttg tttagttgct aggatcttaa gcattcaact aatcaaaaaa
     1441 agactgtttg gaaggtttca atagctttgc cattctaaaa aggatccgcc aatgatataa
     1501 tactactata tcatgccgaa tggggattaa aaatgggaaa tcaaactaaa acggaacttg
     1561 aacttgaaaa agagttgatc catctcttag aaacaggtga aagtcaatgg acatatcgta
     1621 aagaattaaa aactgaagat gctttatggg ataatttctt taagatctta gcgcaaaata
     1681 acacgcaata tctgaatgag gagcctttaa cagctagtga aaaagagcag attaagaatc
     1741 aacttaactt tgttaattac tatgaagcgg ctaaatggtt agctggtgaa aacggcattg
     1801 ctaaagtaca agtgcaacgc gaagatgcaa aactaggaac gattcgttta gaagtcgtta
     1861 aagcagacaa tgtggctggt ggaacttctg tttatgagat tgccaatcaa gttgctttct
     1921 ctggttctcg tgatagacga ggtgatgtga cacttctcat caatggctta cctatgatcc
     1981 aaattgaatt aaaatctcag aatcatcaat gcattgaagc ttttaaccaa gtcaaaaagt
     2041 atgataaaga aggccagttt agaggtatct tttcaacctt acaaatgttt gtggtctcaa
     2101 ataaaacaga tacaaggtat atcgctgcag ctaaagaaaa taaattaaac cctaacttct
     2161 tgacccaatg ggtagatcaa aacaacaaac cacaaaaaga tctctttgcc tttgccaaag
     2221 aagtcctatc tatccctcgt gctcaccaaa tggtcatgac ttactctgtc attgatgatg
     2281 ataaaaaagc actaattctc cttcgtcctt atcagattca tgcaatcgaa gccgttgctg
     2341 aagcgagtcg tcaccgcaag tctggctata tctggcacac aacaggttct ggaaaaacct
     2401 taacttccta taaagtggct cgcaatatcc ttcaaatacc ggccgttgaa aaatccatct
     2461 ttgtcattga ccgaaaggat ttagataatc agaccacttc tgcttttcaa tcttatgcgc
     2521 aaaatgatat ctttgatgtc gatgagacag aagatacgag acaactcatc aaaaatttag
     2581 aatccagtga tcgtcgtgtt gtggtcacca ccattcaaaa actcaatgct atgatcagtc
     2641 agatggaaag ttatgacact ccaaaattca agaaactaaa agagcgtctt gcacacctaa
     2701 atgtcgtctt tgttgtagac gaatgccacc gtgctgtcac gccagaacgt caacgtcatc
     2761 tcacgaatac ttttcgaaac agtcgctggt atggctttac aggtactcct atctttatgg
     2821 aaaataagcg tgctcaatta ggtgatttag cccaaacaac ggaacagcaa tacggcaaat
     2881 gtctccatca atacactgtc aaagaagcca ttcacgataa agcggttcta ggcttccaag
     2941 ttgagtataa gacaaccatt cctgatatgc ctgaagacag tattcctgaa gaagcttatg
     3001 atcatgaaga acatatgtta gctgtcttaa atagtatcat taatcaatca cgtaagaagc
     3061 ttggctttaa taatgggatt ggtcagacat tcgaaggctt attaaccgtt aagagtattg
     3121 ctcgtgccca agcctattat gatctgattc agaaagttaa agctggtgaa acggatttag
     3181 tcatttctaa gaaggtcaaa gaaaaactac cagactttcc aaaggtagct attacttatt
     3241 ctatcactga aaatgacaat gcgtctatca gccgacaaga taaaatgacc aaaaatctag
     3301 aagactataa tcacctcttt ggcactaact ttaccatcga taacttacaa ggctataaca
     3361 gagatttaaa tgatcgctta gcccgtaaaa aagataaatt caaagaccgt catgaacaat
     3421 tagacctcgt gattgtggtt gaccgtctct taacaggttt tgatgcgcct tgtttatcaa
     3481 cgatctttat tgatcgccag cctatgaaac ctcagcacat tattcaagct ttctcacgaa
     3541 ccaaccgtat ctttgaaagt agaaaacatt acggtcaggt tgtgactttc caaacaccac
     3601 ttcgttttaa agaagctgtc gacaaagcgc ttagcctcta ctctaatggg ggtgaaaacg
     3661 acgttttggc cccttcttgg gaagaagaaa aagcaagatt ctttgaaaaa gtaacagtat
     3721 taaaaaatat agttcctgat ccagacgctt tcccaactat tgagagcgca cagacagctt
     3781 ttctcaaaca atacgccaaa gcctttcaag catttgataa actctttgca tctgtacaag
     3841 tctatagtga ctttaatgaa acactgttga gcgaggttgg gttatcagat gaagtgattg
     3901 atacttataa aggcacttac caaaatgtca ttgcagaaat acgaaaacga agagaagatg
     3961 acgaagccat cccagagatc aatatcgact atgagctaga aagtgttcag atggatgata
     4021 tcaactatca ctatatcttg accttaattc aagcctttgt cgatcaagaa caagaagctc
     4081 ttcaagaaag gctcaatgac aatcccatgg atcaatacat ccaagatttg gcaaaatcaa
     4141 accctgctat ggctgactca ctagctgagt tatggcaaga tatccaaaaa gaacccaaag
     4201 cctatgaagg gaaaagcatt gcttatgagt tggataacct cattggtgat aagatccaaa
     4261 gggccatcaa acactttgcg gaccaatgga aggcagatcc tgacaaatta gcctttgtgg
     4321 cgactaatta tcatagtgct aactctacca aacaagtggg catgtcaacc ttaaaagaat
     4381 ccctagacta ccaagcctat aaagaaaaac aaggtgattc tgccatgaat aaactcaaat
     4441 acaagagcca atttgaacgg gagttagttc aattcattag agatcaaatc caacccttaa
     4501 aagggcacta ggaaaggaaa gagatgacaa aatctaaaca gcctcaatat cgctttgacg
     4561 gttttgaagg ggagtgggaa gaaaaagaac taggggatat tgttcaaatt acaatgggcc
     4621 aatctccatc aagtcaaaat tatactacaa acccttctga ttatattcta gtacaaggaa
     4681 atgccgatat aaaaaatgga tatgtttttc cgcgtgtctg gacaacacaa attacaaaac
     4741 aagctgacaa aggtgatatt attcttagtg ttagggctcc agttggtgat gttggaaaga
     4801 caaattatca tgttattatt gggcgtggag ttgctgctat aaaaggtaat gaatttatct
     4861 ttcaaatatt aaaatacttg aaagaaattg gttattggaa aagaattagt acaggttcaa
     4921 cttttgatag cattagctct agtgatatca aatatgctaa aattcaaatt ccctccctcc
     4981 ctgaacaaga agccattggc gaacttttcc aaatggttga tcaattgatt cagttgcagg
     5041 atcaaaagct agcaaccctt aaagaacaaa agcaaacctt cctcaggaaa atgttcccag
     5101 ctcaaggaca aaaagtccct gaaatccgtt tacaaggttt tgatggtgag tgggaagaga
     5161 agaaattggg ggagatatct cggatgtttt caggtggcac tcctaacgta ggtatccctg
     5221 aatactataa tggtaatatt cctttcatta gatctgctga gatcaacagt gatcaaacag
     5281 aattatctat cacagacaaa ggtctatcaa attcatcagc aaaattagtg gaaaaaaata
     5341 cattattata cgctctctac ggtgcaacta gtggagaggt tggactttca agaataagtg
     5401 gagctattaa tcaagcaatt ttagccatta ttcctgagaa aaaatattct tctcttttta
     5461 taaaaaattg gttatataaa caaaaatctt caattattga gaaatattta cagggtggtc
     5521 aaggaaattt atctggttcc attgtgaaag gattagagct ttatctaccc tccctccccg
     5581 aacaagaagc catcggtgac ttcttccaaa ccctagacca acaaatgagt caaatcgaag
     5641 ataaattaac agaacttaaa gcactcaaac aaacattact caatcgttta ttcgtataag
     5701 aaaggactca catggcagag aaaacaactt cactccgtca agcactatgg cattcggccg
     5761 accaattacg tggccaaatg gatgccaatg actataaaaa ctatcttctt ggacttattt
     5821 tttacaaaca cttatctgat aaattactct tggctgtttg tgataatcta gaaaaacact
     5881 tcaatacctt tacagaggct caaaaaatct ttgaagatgc ttatcaagat gaaggcctaa
     5941 aagatgacct catttctgtt gttactggtg atttaggtta ctttatcgaa ccaacactga
     6001 cctttgaaaa actcatccaa gatgtttatc acaatacttt ccaattagaa tcattagctc
     6061 aaggttttcg cgatattgaa caaagtggtg aagactttga aaacttattt gaagatattg
     6121 acctctactc taaaaaatta ggctctactc ctcaaaaaca aaatcaaacc atttctaatg
     6181 tcatgaaaac attaaatgaa attgactttg aggcagtaga tggggatact ttaggcgatg
     6241 cttatgagta cttgattggt gaatttgcca gtgagtcagg aaaaaaagca ggtgagttct
     6301 ataccccaca agctgtctct cacttgatga ctcagattgt ctttttaggt cgtgaagatc
     6361 aaaaaggaat gaccctctat gaccctgcta tgggatctgg atcactcctt ttaaatgcta
     6421 agaaatatag taaccaatcc gataccgttt cttactatgg tcaagaaatc aatacttcta
     6481 cttataactt ggctcgtatg aacatgatgc ttcatggcgt tgccatcgaa aaccaacact
     6541 taagtaacgc tgataccttg gatgcagact ggccaacaga tgaaccaacc aactttgatg
     6601 gggtgttgat gaacccacct tattctttaa aatggtcagc gactgctggt ttcttaacag
     6661 atccacggtt ttcaagttat ggtgtattag caccaaaatc aaaagctgac tttgcctttt
     6721 tacttcatgg tttctatcat ttaaaaaata caggaactat ggcaattgtc ttacctcatg
     6781 gtgtcctttt ccgtggagct gcagaaggta aaattcgcca aaaactactc ggacaagggg
     6841 ctatcgatac cattatcgga ctcccatcaa atatctttta taatacaagc atccctacga
     6901 ctattatcat attaaagaag aacagaacca acaaagatgt cttctttatc gatgcttcaa
     6961 aagaatttga taaaggcaaa aatcaaaaca caatgacaga tagccatatc aaaaagatcc
     7021 ttgatgctta taagagtcgt gataattctg ataagttttc atatttagcc tcatttgatg
     7081 aaatcattga aaatgactat aacttaaata tcccacgcta tgttgatacc tttgaggaag
     7141 tcccagttaa accactgcca gaattagcta aacagctcag tgacattgat caagaaattg
     7201 ccaaaacaaa tgccaaacta gatcaactca tgaaacaact agtcggaaca accaaagaag
     7261 cacaagacga attggatact tttagaaact aaaagacaaa aaaacaccac agtagatgat
     7321 tactactgtg gcgttttatt taaaattgag tagtgaacct ttattgagta cttatcaaac
     7381 aagattctcc ttcttcacct ataaatcaaa atagaatcat ctcatctaac tttactttgt
     7441 ccgtttcttt gttttattta aaatagttat ttgaagttac aatgatttct caaacgttta
     7501 gaaagcttaa acacggttaa gagaaatttt caggacaact tttgatcctt ccacaaaaac
     7561 catggtgcga accataaatt agttccaatc gttgatatat aagcatatat taacgttctg
     7621 ggagttgtga agctttacga gtttttttag acctggttta aacaactttt gtttgactaa
     7681 atttaaaaag cttttcatat caggcattgc cctacttttt ataaaagcgt tatctcaatc
     7741 aaaaagaact caaaaacaat gagtttaaat ctgggtattt aacaggaaat ccctagcaac
     7801 gacacaagta aaacttatgt cgtttgatta tctgcaactc agaaatccat aaaataccct
     7861 aattgttcgg ctttgtagat agcctcttgc ttattattta ccaaaagctt tgagtagatg
     7921 tgggtcaaat gattaaatac tgttctccta ctaatttgta acgtttcctc tatttctttt
     7981 atagagaatc ctttcttact caaatttaag atagctattt cctggtcagt taaagattca
     8041 acataatcct gagattcgat ttgttcaaaa tacttttttc cagaatccac tttttttaag
     8101 atagaaatga gttgtttagg gtctatattt ttatctacaa aaccgtatgc tcctactttt
     8161 tttgccctct ctctatagat tgatttaaca tatcctgtca acacaacaac tttcaaatga
     8221 ggagtagact gtatgagttc ttttgctatc tccaatccat tttctttaga aatatttgtt
     8281 aaattaatat caagcaatat aatatcgtac ttagacaaat caatcgtcac atcgttaaaa
     8341 tgagaagtaa tcgtatctat gacatctact tcatcatact gttggaataa cagttggata
     8401 ctctttgcaa atagtctgtg gtcatcaatt aataaaatct tcataacaca atttccaatc
     8461 tatgggaagt aatattctga tagtaaattg tttagtatcc atttgtagtt ctagatctcc
     8521 atcaaaagct gctagtgttt cttgaaatga tttcaatcct ctgccataac ttatagagtg
     8581 tactttttcc actacttgat tgctctcctc aatgataata atatcagatt gaatcgttaa
     8641 agataaacga atgtcttttc catctccata ttttatagca ttgtttatta gctcttttat
     8701 aaacctataa acaatatctc catatgggga tggcactacc atattatctg aacagttaaa
     8761 atacaataag gtattacttt ttctactttt aacaatatca tcaaaaagag actgtatgtt
     8821 ttctttcatt gtttgattag cgggaactat tgggtggtaa gtatcaattt cttctctgat
     8881 accagaaact aaatcattca actcattaac aataaaacca tgtgttatat tactattttc
     8941 tagagaaagc aagtttttta tcgctatgat attttgtaaa acatcatcat gcaaataatt
     9001 tgagaactcc actctcatgt tttcctctga tttcataaaa tagttcagtc ttctattttc
     9061 atagtcaaaa ttttgtttgg agttttctaa ataataaaag atgcaagaaa ttaccactag
     9121 acaaaataac gtgcttgcgt c
//
LOCUS       DAUGSW010000043         8628 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUGSW010000043 DAUGSW010000000
VERSION     DAUGSW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8628
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.043"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            438..640
                     /locus_tag="VIB18_001409"
                     /pseudo
     CDS             438..640
                     /locus_tag="VIB18_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            842..1222
                     /locus_tag="VIB18_001410"
     CDS             842..1222
                     /locus_tag="VIB18_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEQ8766411.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            1222..2070
                     /locus_tag="VIB18_001411"
     CDS             1222..2070
                     /locus_tag="VIB18_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8766412.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            2195..3403
                     /locus_tag="VIB18_001412"
     CDS             2195..3403
                     /locus_tag="VIB18_001412"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEQ8766413.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDH
                     IEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            3400..5277
                     /locus_tag="VIB18_001413"
     CDS             3400..5277
                     /locus_tag="VIB18_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8766414.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLEFLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKGGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNLINGDLEPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGNYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(5375..5452)
                     /locus_tag="VIB18_001414"
                     /pseudo
     CDS             complement(5375..5452)
                     /locus_tag="VIB18_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            6168..6578
                     /locus_tag="VIB18_001415"
     CDS             6168..6578
                     /locus_tag="VIB18_001415"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8766415.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLYGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(6660..>8628)
                     /locus_tag="VIB18_001416"
     CDS             complement(6660..>8628)
                     /locus_tag="VIB18_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEQ8766416.1"
                     /translation="TSFTLLVTDVQADQVDVQFLGVNDFHGALDNTGTAYTPSGKIPN
                     AGTAAQLGAYMDDAEIDFKQANQDRTSIRVQAGDMVGASPANSALLQDEPTVKVFNKM
                     KFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEASHQTIVIANVIDK
                     KTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEHYQFLDVAETIA
                     KYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHSIDIIFAGHNH
                     QYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAPGIKTENSDI
                     KAIINHANDIVKTVTERKIGTATNSSTISKTENNDKESPVGNLVTTAQLTIAKKTFPT
                     VDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDVLNQQYDE
                     NQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVNDFLYGGG
                     DGFSAFKKAKLVGAINTDTEAFITYIKNLQASGKTVNATIKGVKNYVTSNLESSTKIN
                     SAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTINKNTISSSTLPI
                     TGDNYKMSPIMTILALISLGGLNAFIKKRKS"
BASE COUNT         2744 a         1379 c         1794 g         2711 t
ORIGIN      
        1 aattttttaa aataatactt aattttttaa ataattttta ataaacgtaa acaagcgatt
       61 gacaatggag atatcacaag aggtacagta gtggttgtgc ttaaaatgga cggttttttg
      121 atgatatgtt gccgcatgag gaagtgagca ataggagagc tgtgatagaa gaaagagagg
      181 aagaagcgtt gatgaaatta gacaaataaa aaaaagacct catccagaag aggtcgtggt
      241 ataactgggg acgataggtt caattgataa aaaatcttgt tagcttacga tctatgttgt
      301 tttgaatgcc tttaactcaa catcgttaat ggattttgag ataaaaaaat aaatccaata
      361 gtctggtact ttcctatttt ttgtctgtta aaacgttttt attttataat ggataaaagg
      421 agaagaaggg cggagcgatg attaagctct atgggtttaa gtatgggtta gttggagagg
      481 ttttgcggcg gattgaacgc ctaggattta cgtttgagcg attagagcta agacaagcta
      541 gttcgaaata cttggctaag catgatgagg ccttggtgat aaaccttttt atcctggact
      601 taaaacttac ctgaccagtg gttctgtttt aattgaggtg cagtacaaga ccactaacgg
      661 gtgttttttt gatataatgt cagtataagg acgactaaat ataaataggt gaaaaaatag
      721 atatctgttc gagagatagc actgtttaaa acgttatgcg aaaatagtag tttaggggct
      781 actttaataa tcttcaaatc tatgctataa tggatcatat tgataccaag gagaataaaa
      841 aatgcaatta gttcgtgaaa aagaatttgt caaccagtac cattatgatg ctagaaattt
      901 agagtgggaa aaagaaaacg gaacaccaga gaccaatttt gaagtgactt ttcagttgat
      961 tgataaagat gagcagcaaa aagaaacagt aattgtatct gtattgcaat ttgttattgt
     1021 caaagaagaa tttgttatta gtggggtcat ctcacaaatg gttcgtattt tagatcgttt
     1081 agtggataaa ccaagcgaat ttacgcaaga ggaagttgaa tccttagctg ctcctttgct
     1141 agacatggtt aagcgattga cttatgaagt cacagaaatt gccttggatc gtccaggtat
     1201 tcatttggag tttaaaaatt aatgaaatta gcagtaatta ctgacagtac agcaacacta
     1261 ccaacagatc tgaaacaaga taaagctatt tttagccttg atataccagt tatcattgat
     1321 gatgagacct attttgaagg tcgaaatttg agtatagatg atttttatca aaagatggct
     1381 gactcccaaa atcttcccaa gacaagtcag ccaagtttat ctgaactaga taatctttta
     1441 ggacttttgt cttctaaggg ctatacacat gttattggct tgttcttagc tggaggaatc
     1501 tcaggctttt ggcaaaatat tcaattttta gctgaagaac atcctgagat tgaaatggca
     1561 tttccagaca gtaagatcac atctgctcct ttaggtagta tggtaaaaaa tgtgctagat
     1621 tggtcacgtc aaggaatgac atttcaagct attttaaaca agctgcaaga acagattgat
     1681 gggacgacag cctttattat ggttgatgac cttaatcatc tggttaaagg cggacgcctg
     1741 tcaaatgggt ctgctcttct tggaaatctt ttgagtatta aacctatctt acgctttgat
     1801 gaagagggaa aaatcgttgt ttatgaaaaa gtgagaacag aaaagaaagc catgaaacgc
     1861 ttggttgaga ttttaaatga cttgatagca gacggtcagt ataatgtgtc tattattcac
     1921 tcaaaagcac aagacaaagc tgattatttg aaacgactct tacaagacag tggttatcaa
     1981 tatgacattg aagaggttca ttttggagcg gtgattgcta ctcatttagg agaaggagcc
     2041 attgcatttg gcgtaacacc gaggctttaa ttgtcgatta gaaaaaatag ttaattgcaa
     2101 gaatcactaa aacaataaca aaatgtgata gaacccaagt agcctaatca cactttagat
     2161 tgggctagtt ggatgatagg ttagaaaaca acgtatgaaa ttaatgacaa tgccttctga
     2221 gtttcagaag gctttaccca tattgactaa aataaaagaa gctggttatg aagcctactt
     2281 tgtgggagga agcgtcagag atgttttact cgagcgtccc attcatgatg tagatattgc
     2341 aactagttcc tatcctgaag agactaaagc gatttttaac agaactgtcg atgttggcat
     2401 tgaacatggt acagtgctcg tgcttgaaaa tggcggtgag tatgaaatca caacctttag
     2461 gacagaagat gtctatgttg actatcgccg tcctagtcag gtttcttttg tgcgctcttt
     2521 agaggaagac ttaaaacgaa gagactttac cgtcaatgcc ttggccttgg atgaaaatgg
     2581 tcaagttatt gataaattta gaggactcat tgatttggag caaaaacggt tacgagcagt
     2641 gggtaaagca gaggaacgtt ttgaagaaga tgcactacgc attatgagag gctttcgatt
     2701 tgcggcgagt ctggattttg acattgaagc tgcaactttt gaagctatga ggagccattc
     2761 acctctattg gaaaagattt ctgtggaacg ttcttttact gaatttgata aattattgat
     2821 ggcaccgcac tggcgaaaag ggatttctgc catgattgct tgtcaggctt atgactattt
     2881 accaggcttg aagcagcagg aagcaggctt gaatcatctg atagtttctt tgaaagataa
     2941 ctttaccttt agtgatcacc accaagcttg ggcttatgtg atgattagtt tagccattga
     3001 ggatcctaaa agcttcctaa aagcatggaa gacttcaaat gattttcagc gttatgtcac
     3061 aaagttgatt gctctttata gaattcgtca ggaaagatct tttgaaaaat tggatattta
     3121 ccagtacggc aaggaaatgg caagtctagt ggaaggcctc cgaaaagctc aaagcttatc
     3181 tgttgacatg gaccacattg aagctttaga tcaggcgcta gccattcata acaaatacga
     3241 tatcgtcctt aatggttctc acctgattaa ggattttggg atgaaaccag gtcctcagct
     3301 agggcttatg cttgagaaag ttgaattagc gattgtagag ggacgcctag ataatgattt
     3361 cactacaatt gaagcatttg ttagagagga attagcaaca tgagccattt tttggtggag
     3421 aaattgacaa aaacggtggg agataaaaca gtctttcagg atatttcctt tattattcat
     3481 gactttgacc gtattgggat tattggggtt aatggaacag gaaaaacaac tcttttagat
     3541 gtcttgtcgg gaaggcttgg ttttgacgga gaccattcac cattttctaa agccaatgat
     3601 tacaaaatcg cttacttaac acaagatcct gaatttaacg atgcatcctc tgttttagat
     3661 acggtattgt catctgatgt taaggcgatt cagctgattc gtcagtatga actattgatg
     3721 gcgaattata ctgaagataa acaagagacc ttagagttcc tcatgtctga aatggatcgc
     3781 ttagatgctt ggtctattga aagtgatgtc aaaacagtcc tatcaaaatt aggcatcacg
     3841 gatttggaac aaaaagtggg agacctatca ggtggtatga gaagacgtgt ccagttagct
     3901 caagtattgc taggagctgc tgacttactc ttgttggatg agccgaccaa ccatcttgat
     3961 attgacacca tcgcttggtt aacaacctat ctcaaaacag ctaaaaaaac cgtccttttt
     4021 attacccatg accgttattt ccttgatcat gtggccaccc gtatttttga attggataag
     4081 gggggactga cagaatatca aggcaattac caagactatg tgcgcttaaa agcagaacaa
     4141 gacgaacgag atgctgctaa tttacacaag aagaagcaac tctataaaca agaattagcc
     4201 tggatgagga cgcagccaca ggcgcgtgca accaaacagc aggctagaat caatcgtttc
     4261 actgacttga aaaaagaagt tcaccaagac agttctgcgg ataagttgga gatggctttc
     4321 gaaacgagcc gaattgggaa gaaggtgatt cactttgaag acctttcttt tgcttatggc
     4381 gaccgacagt tgattaagga ttttaacttg attattcaaa ataaagatcg tattggaatt
     4441 gttggagata acggcgtcgg aaaatctacc ctgttgaatt taattaatgg agatcttgaa
     4501 ccaacttctg ggaagcttga tattggagat actattcgtg taggttattt ctctcagcag
     4561 ctcaaagata tggatgagac caaacgggtc attaattacc ttcaagaagt ggctgatgag
     4621 gttaaaacaa gcgtgggaac aacgagtatc agtgagcttt tagagcaatt tctttttccg
     4681 agatcaagtc atggcacgct gattgctaaa ttatctggtg gggagaaaaa acggctctac
     4741 ttgctaaaac tgctcattga aaagccaaat gttcttctcc ttgatgagcc aacaaatgat
     4801 ttagacattg ccaccttgac ggtcttagaa aactttttag ctaactttgc aggaccagtc
     4861 attacggtta gtcacgatcg ttatttccta gacaaagtag ccactaagat tttagccttt
     4921 gaagaaggcg atattcgtat tttttatggg aattacagtg attaccttga tgaaaaagct
     4981 tttgaaaaag aaacagttga ggctgactta gctaaagcaa tagtcactga agaagtgcca
     5041 cttcctccga aagaggagaa aaagcgcatg tcctaccttg aaaaacaaga atgggctcag
     5101 atagaagata aaatagcaac tattgaggct aatattgaag aaattgaaaa ccaaatgtta
     5161 actgtagtta gtgattatgg ccagttagct caattacaaa aggaactcga tcagcgcaat
     5221 aatgatttat tattggcgta tgaacggttt gagtatttga gtggactaga catataagta
     5281 tactatggta atgttatgtt tataataaac aagtgataat agaaaagaag tgctcttgca
     5341 ctgagcccca aaagttggct actctatttg aagtaaagga tttagttctg tattgtagag
     5401 gactaagtcc ttttcgtttt attttgatac gtttattgtt gcaataatcg atgataatag
     5461 taggtagaac gagtcaattt agccgttctt aaaagaaaat ctaatcagaa ctcgtctttg
     5521 tccattcttt ataatggttt tttgtcttct tctttgcaga gatgcttctt tcaaacggag
     5581 ttccctcagt ttttaagcgc taaatgtcta gcttatcttc atagcttaat gtcatacaaa
     5641 aacaccccaa acgttagatt tttttatcta acgtttgggg tgtagtttac attatggcgc
     5701 ttcttttcta ttattacgtg aggaaaaatc aagtaaaaaa gttaagtcaa ctgaaaaact
     5761 tgacagaaat attcagaaaa tttataatac taactattaa caacatatca gctattaaag
     5821 catttcaaac agcaggtgtt ttgtttggac ctatcaaggc tgcaaatgca agagaaagca
     5881 gtatctggtt tgaaaatctc acaaagcaat aacgatctct cttagacatt tgaagaagca
     5941 gacagtaaat tcgataatat tgtgatgaga atttaccaac aatctgctga tgcaggtcaa
     6001 tttttattta gtactcatat tgcagaattt cataaagttg cccaagatat cttgaaataa
     6061 ggaatcacct gatgttttaa acagatgata ctaagtctat cctatggtga taatagtcca
     6121 ttgaacatgt agtttatgaa ttaaaaagaa ggtttaagga gataagaatg attagagaaa
     6181 tcataacaga tcatttttta ttacagcaaa aagcgcaagt cgccaagaaa gaagatctat
     6241 ggattggcca agatttacaa gataccttag ccttttatag acaggaatgt cttgggatgg
     6301 ctgccaatat gattggtgaa caaaagcgca ttgttattgt gagtatggga tttattgatt
     6361 tggtgatgtt taatcctgtg atggtttcta aaaagggaat ttaccaaact aaagaatctt
     6421 gtttgtcgtt atatggctat cgcaaaacac agcggtatga taagattact gttgagtatt
     6481 tggaccataa ttggcgacca aagcgattaa gcttaacagg cttaactgct caaatatgcc
     6541 agcacgaatt agatcatcta gaaggtattt taatttaaca aaaaacctag agtaggacgc
     6601 tttaggtttt tttggcaaag atgcctgatt atataagggt gatcgattac tagtaaacgc
     6661 taggatttcc tttttttaat aaaagcgttt agtccaccta agcttatcaa ggcaaggatt
     6721 gtcataatag gagacatttt ataattgtcc cctgttattg gaagagtgga actagagata
     6781 gtatttttgt ttatcgttgt ttcttttttg ccaaggctgt tattagtgtt ttcagtagaa
     6841 gtcaaaaggt ctgaaatgac ttcactagac actatattgc catcacgatt tctaaaaacc
     6901 ttactaatga tactgtgttt accagcacta ttaatttttg ttgagctttc aaggtttgaa
     6961 gttacataat ttttaacccc tttgatagta gcattaacag ttttacctga tgcttgtaaa
     7021 tttttgatat atgtgatgaa agcttcagta tctgtgttaa tagctccgac taatttagct
     7081 tttttaaatg ctgaaaagcc atcaccgcca ccataaagaa agtcgttgac aacaacggtg
     7141 taagtagttg ttaagttaat ttcttcacca ttgtctttat aaaccttaac tatcttgaag
     7201 ggggtatcag agttcttagg atcattatct gtataagtgt atgttaaacc tgacatttga
     7261 agaaaatagg tctggttttc atcgtattgc tgatttagga catcgtaaat gtgttgacca
     7321 gtcatttgaa tgacttgaag gatattacca aatggttgta cagcctgtgc agctccccag
     7381 gtgatggtcc ggtcattttt gacaactagg tcacttcgaa taccaccatt attggtcata
     7441 gcaaagtcaa cagttggaaa agttttctta gcaatagtaa gctgagccgt tgttactaag
     7501 ttaccgacag gggattcttt atcattattt tctgttttag aaatagttga agaattagtt
     7561 gcagttccga tttttcgttc agtaactgtt ttaacaatat cattagcatg atttattata
     7621 gctttgatat ctgaattttc tgttttgata cctggtgcta cagcaacaac atttgctgat
     7681 ggagttttaa taaaatcatt ggtatcagta tctagcgtac cacggacatc tgcataagct
     7741 tttccttgag agagggcttg aacgatacgt gttttaccga tagttccatt agtgtattga
     7801 tgattatgtc ctgcaaaaat aatatcaata ctatgttcgg gatagatttg gttcactttt
     7861 tccataaccg tagccatttc atgatcaaca acaccatctt tacttgttgc aggaatatga
     7921 gctaaaacca caatagcatg aacatgttgt tcttgcagtt ctttagcata tttggcaatg
     7981 gtttcagcta catctaaaaa ttgatagtgt tcatagtttt gctttaaaac gagatttgga
     8041 atctctgtag tcacaacacc aatgaagcca atcttaacga ttttgtcatt aatggctatg
     8101 tcttttatag cataaggttt ccaaccatag gggatatcat tggttttttt atcaatgaca
     8161 ttagcaatga cgatggtttg atgcgaagct tcgtgctcat attgtttggt gatatcatta
     8221 attgttgatt caggatcagg cgcttgacct gtcatgatac ggttaaattc atctagtcct
     8281 tcgtcaaatt catgattacc aagagtgcca tattcaaatt tcattttgtt aaagactttc
     8341 acagtaggct catcttgtaa aagtgcagag ttagcaggac tggctccgac catatctcca
     8401 gcttgaacac gtatacttgt tctgtcttga tttgcttgct tgaaatctat ctcagcgtca
     8461 tccatataag cacctaattg agcagccgtc ccagcatttg gtattttacc acttggtgtg
     8521 taagctgttc cggtattatc aagagcgccg tgaaaatcat tgacgccaag gaattgcaca
     8581 tcaacttgat ctgcttgaac gtctgtaact aatagagtaa aactagtc
//
LOCUS       DAUGSW010000044         8613 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUGSW010000044 DAUGSW010000000
VERSION     DAUGSW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8613
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.044"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(72..2648)
                     /locus_tag="VIB18_001417"
     CDS             complement(72..2648)
                     /locus_tag="VIB18_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ8766417.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLRLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPIKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPPNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(2731..4350)
                     /locus_tag="VIB18_001418"
     CDS             complement(2731..4350)
                     /locus_tag="VIB18_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8766418.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(4429..5301)
                     /locus_tag="VIB18_001419"
     CDS             complement(4429..5301)
                     /locus_tag="VIB18_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8766419.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    5424..5665
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5720..6742
                     /gene="trpS"
                     /locus_tag="VIB18_001420"
     CDS             5720..6742
                     /gene="trpS"
                     /locus_tag="VIB18_001420"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEQ8766420.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNETKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     gene            7021..8502
                     /gene="guaB"
                     /locus_tag="VIB18_001421"
     CDS             7021..8502
                     /gene="guaB"
                     /locus_tag="VIB18_001421"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEQ8766421.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         2889 a         1391 c         1633 g         2700 t
ORIGIN      
        1 tctagctctt gagatgcttt tagtatattg acttatttgc caaattgata aaaaaatctg
       61 attttttcgg actaaagtaa tttagacttt atatctatgt acttatacaa aagcatataa
      121 gcgataattc ctacacaaga tagagataac cctaatttaa aaccattagg aataaaggta
      181 aggataacac gtccctttcc tttaggaata gtaactgata gaaatcctcc ttgtgctttt
      241 ttgactggaa gatttttccc atctttttgt gctgaccaac ctttatcgta aggaagtgta
      301 aaaataagag aacctttcgt ttttgaatta taatcagtga ttaccgtatt acttttagcg
      361 taagtatgaa catttttttg tttaatacta ttcattgctt caaggtaaga ttcaatagac
      421 aaactataaa aatgaggttc cttaaaacta atttgtttat tttttggaaa aacaaacgaa
      481 aatgtagcaa ctttggcatc ggcgaaatat cctaaatcaa aaaaagagta agcgttatct
      541 gtagtatata tgaaattatg attatctgtc tgaatacgca cctctttagc atcaggattt
      601 gaaaatataa tattgggtat gctaacatag agttgactat gtttagggat gttaatttga
      661 taattaaggg taacggagtt ttgataatca gaagcttgtg cagatatttg tccgttaaat
      721 tgattagcac cagaaataag ttgagctggc tgtaagttaa aataggttaa agatttccca
      781 cttagttggt taagtaattt ggtttggtta tcaagggtat tgacatttag gttgacatct
      841 ttgtaaacat tacgtgttaa tatagctaaa gggctactat agtgattttg ataaagagta
      901 gtattcccgc tagtttttag ttttgtaaat ccaaatttat ttggaggtcc ttcgctaaga
      961 ttatatttta taccaagtag actgtccata ataatagtat tgttttggta tctaaggttt
     1021 aaatttgtgc ctttagactg aaatcccaat cgatccaata aagaactaga tagtctattt
     1081 cttacagagg aaaattgtga aatgccgtaa taattaaatt tcatgctatc gttccctgtt
     1141 tggggaagta gcctttccat tctaaaaaaa ggttgactat tttttgacac agagttgaca
     1201 aggttgttaa tatcctttaa ttgactatta tatatctgtc gtgatgggaa tccccactcc
     1261 ttattaattc cttgaagctg gtagtaggtg tttaaccctg attcaagaag gctaaagata
     1321 agtatgaaag cagaaataaa agtagatggg atttgagaat ttctaaacga aaatagtgaa
     1381 atagtataac ctaataataa aaaaacacta agtaaaaaaa gagttaaagg tagaaaatta
     1441 tattgttgag aaaagctata aggaagagat gtcagtataa tgaggaaaat aaaagcaaaa
     1501 cctgctttta tttgagtcac ttcttttagt cgagagagag tctcacatgc gagtaatagg
     1561 ataactatgg aaaaagacca agcgtagcga tgcaaaaaca tatttggtga gtgcatcccc
     1621 tgccaaaaaa gatcaagtgg ctgtaggtaa aaacttatta taataaaagt taacaagcag
     1681 gcattggcta attttatttt taaagggata ctttctaaag taaaataaat aacactaagc
     1741 attaggggaa ataatcctac gtaaatcata ggcagagcat taaacttggt agtatcgtac
     1801 actcctattg agagcttagc aggtatatcc aaaaaccaag cattgttcgt aactaactgt
     1861 tttatcgggg atagattctc tccataagtt gacaaatcta gataggtagg aagtattact
     1921 agagcacttg ttaaagcagc acatattgac acagctgtaa acctaacaaa agcgataaac
     1981 attttgttaa aatcattgag acgtaaaaga caaactaagg cgtaaagaat acaaaaaaga
     2041 gcaatcatgt agccaaagta gtaattttga atgaataata atgatatcga aagataataa
     2101 gttctggttt tattttctgt gataagttta tttaatccaa gtacaacaag tggaagaaga
     2161 atgaaaacat ctaaccaaga atttagttcc atttgacttg tcaagaagct cattaagcta
     2221 taaaaaactg agatggaaat catcaagaaa gcactgattt ttggatataa tctatgaaaa
     2281 gaatagcatg cagctaatcc tattaaccca aattttatca aggtaaacaa atagatagca
     2341 tctggcatag aggttaaatt aaaaaagaaa agtaatggag aaaagaaact gccaagataa
     2401 taacacatta aagcataaaa atttatccct agtccgcttg taaaggtata aaaaaaacta
     2461 tcagaaccgt gcatgatgtt acgaaagttc tgcgcaaaaa taacatactg atgaaaagca
     2521 tcactagcta gaattgtttt atcactatta taataaatgc ccatcgatag aaggatgata
     2581 aatataatac taagagggaa caaaaaacta gcaagtccag caattatcca tttattatta
     2641 tttttcataa attatatggt ctttcgttta caaattttaa aaaagaggct aggaagagat
     2701 cttcttagcc acctcattta tcataaggtt ttatttccaa agttcagcaa ctcgggcttg
     2761 gacttctgga ttgtcaagga attcgtcata agtttcatct atacggtcga taacaccatt
     2821 ttttgaaata acaacgatgt ggttagcaat cgtttgaata aattcatggt catgactggc
     2881 aaagataaca gattctttga agtctttgat cccatcatta agacttgaaa tagattccaa
     2941 atccaagtga tttgttggat catcaagaat aagaacgttt gatttcaata gcatcaactt
     3001 agaaagcatg acacgcactt tttcgccacc ggaaagaacg ttaacagatt ttttaacttc
     3061 gtctccagag aaaagcatcc gtcctaggaa accacgtaaa aaagtatcgt catcttcacc
     3121 ttttgaggca aattgacgta accattcaag aatagattct tccgtggcaa aatcttttga
     3181 attgtcttta ggcaagtaag aacgacttgt tgtcactccc catttaatgg ttccttcgta
     3241 gtcaatatca tctgctaaag cacgcataag agcggttgtt tgaatatcat tttgaccaat
     3301 aatagcagct ttgtcacctg gacgtaaaat gaaactgata ttatcaatga ttttctctcc
     3361 atcgatcgtt acagaaagat tttcaacagt gaggaagtca ttccccattt cacgctctgc
     3421 tttaaaatta ataaatgggt atttacggct tgagggaaca atttcttcta attcaatctt
     3481 atcaagcatt tttttacgag aggttgcttg ttttgattta gatgcgtttg ctgagaaacg
     3541 ggcaacgaat tcttgtaatt ctttgatttt ttcttcggct ttagcattgc ggtcagcttg
     3601 taaacgagcg gctagctcag aagattgttt ccagaaatcg tagttaccca caaagagttt
     3661 gattttacca aagtcaaggt cggccatgtg agtacatact ttattcaaga agtgacggtc
     3721 atgggaaaca acgatgactg tattttcaaa atcaatcaag aaatcttcca accatgaaat
     3781 agattgaata tcaagaccat tggttggctc gtcaagtaat aaaacgtcag gcttaccaaa
     3841 gagcgcttta gcaagaagga ctttcacttt atctccatta gccagttcac tcatattttg
     3901 gtagtgaagg tcttctggaa tatttagatt ttggagaagt tgagaagctt cactttctgc
     3961 ctcccagcca cctaattcag caaagatacc ttctagctca gcggcacgaa ccccatcttc
     4021 ttctgaaaaa tctgctttca tatagatagc gtctttttct ttcatgatat tgtaaagttg
     4081 ctcattaccc atgattacaa catcaatcgc acgttcttct tcataatcaa aatgattttg
     4141 gcgaagaaca gataagcgtt cgtcaggtcc taaagagata tgaccagtac ttggttcaat
     4201 atctccagca agaattttaa gaaaagttga ttttccggca ccattcgcac cgattaagcc
     4261 gtaagtattg ccggctgtga atttgatatt aacatcatca aatagttttc gatcactaaa
     4321 gcgtagtgat acatcagaaa ctgtaagcaa tttgtcacct cattttattt atctaagctt
     4381 cattgtacct aaaatagtcc cctttttcaa tcagaaaagg gctaatcact acataggcaa
     4441 taaaacgtct ttgtcttcac gtttgtattg tttagtcaaa ctaaatcctc ttcccataac
     4501 ttgagctgct ggcatgacaa caataaaggc tgtgtcgtca atttcgagga ttttttcttg
     4561 gagagtgggt aattcgtgac ttgatacaat agccattaac ataattttat cagaagtagt
     4621 ataaccaccg cgaataggaa gtttagtcac tccacgatcc ataacagttg tgatatattc
     4681 tcgaatagct tgataatctt tggaaataat cataacattt ttggatgagt caaagccatt
     4741 ttccataacg ctaatcacat aaccaattac gaaaagtcca atcgtagaat acatcacgtc
     4801 atctgcagaa agtgcaataa atcccataag gacactaata ccatctacaa ttgtcattgc
     4861 aactccaaga gataaaggag agtatttatg aagtatttgt gttagaattc cagttcctcc
     4921 tgtcgaagag tttccccaaa aaaccattcc taaaccaatg ccacagataa taccaccaaa
     4981 aatagctgct aacaactgat tgtgtgtcag agtaggtaat gaattggttg aacggatggc
     5041 aataggatat atccaagaac cataaagtgt tttaataaaa ttttgttttc caagaaagaa
     5101 gtaacacatt aataataagg gaatattact agccattaaa aaaagcgacg gactaatgcc
     5161 aaatagagct tttataacaa ctgcaatacc aaccataccc cctgatgcaa tatgattgtc
     5221 gacaaacatt gtattgaaac caatagctgt tatgaatgag ccaattgtga caagtagtaa
     5281 atcaatccct cgttttttca tgcttttaat ctcctttata actggttaaa aatagtagac
     5341 tcattatctc ttaaatgtac tgagaccgtc aagtcatatt ttcaaaaaat ctggtgaact
     5401 tgacaagaag tttaaaattt catagaataa atctaaatta gaagagtatt cttttcatgt
     5461 ttttagagag ttagtggttg gtgcaagcta acaacagaaa aggtgaaatg gactaatgat
     5521 tatttgaaag gaaaccataa ctttcaggtt ggcacccctt accgtgcagc ttctttcatt
     5581 gagaagattg agatagtatc tcgttttgat aaagcagatg ctaattgagg tggtaccgcg
     5641 tattacttgt aataacgccc tcacgtttta atagcgtggg gactttttgc tatatcaaga
     5701 gatagttagg gagaaaatga tgacaaaacc tattatttta actggagata gaccaactgg
     5761 aaaattacat ttaggtcatt atgtcggaag tcttaaaaat cgtgtctttt tacaaaatga
     5821 aaccaagtat aagatgtttg ttttcttggc cgatcaacag gcactgacgg atcatgctaa
     5881 agaatccgaa ttaattcaag aatctattgg aaatgttgcc ttggattacc tctctgtcgg
     5941 tttggatccg aagcaatcaa cgatttttat tcaaagtcag attccagagc tagctgaatt
     6001 gagcatgtat tatatgaatc tggtatcatt agcacgtttg gaaagaaatc ccactgttaa
     6061 aaccgaaatt gctcagaaag gttttggcga aagtattcca tctggttttt tggtttatcc
     6121 agtgtcacag gccgctgata ttacagcatt taaagcgaat ttagtacctg taggtaacga
     6181 ccagaaaccg atgattgaac aaacacgtga aattgtgaga agttttaatc atacttacca
     6241 tacagactgt ttagtagaac ctgaaggtat ttatccagaa aatgaaaaag ctggacgctt
     6301 acctggtctt gatggcaatg ccaaaatgtc taaatcattg ggaaatggaa tctatctctc
     6361 agatgatgca gataccgttc gcaaaaaagt gatgagcatg tatactgatc caaatcatat
     6421 taaaatagaa gatcctggtc aaattgaagg gaatatggtc tttcattatt tggatatttt
     6481 tgctagaaaa gaagatcaag ctgatatcga agcaatgaaa gagcattatc aaagaggtgg
     6541 tttaggagat gtgaaaacga aacgctacct tctagatatt ttagaacgtg aattagcacc
     6601 tattcgtgaa agacgtttgg agtacgctaa agatatggga gaggtgttcc gtatgttaca
     6661 agaaggtagt caaaaagcaa gaactgtggc agccaagact ttatcagaag tgaagtcagc
     6721 aatgggtatt aattattttt aatgttttag agaaaaagct aagttagtaa tgataagata
     6781 attactatta tcaaagcagg acctaatttg tcatttcttt acaggatagt agagattatg
     6841 ttttatatag tcttattttt gattaataaa aaacggataa tactgatata ttatgctgat
     6901 agtgacttca gctgtaggaa tattttattg acaaatgatt ttagcgtgat atgatagtaa
     6961 caataaaaaa tagactaggg taatattccc taaaaaataa aagaaaagag gattatctgg
     7021 atgtcaaatt gggacactaa atttttgaaa aaaggctaca cttttgatga tgtcttgctt
     7081 attccggcag agagtcatgt tcttccaaat gaagttgatt taaagacaaa gctcgcagac
     7141 aatttgacat taaatattcc tattattaca gcagctatgg atacggttac tggtagtaaa
     7201 atggctattg caattgcgcg tgcgggtggt ttaggtgtta ttcataaaaa catgtctatt
     7261 actgagcaag cagaagaagt tcgcaaggta aaacgttctg aaaatggtgt catcattgat
     7321 ccattcttct taacacctga acacaaggtt tcagaagctg aagaattaat gcagcgctac
     7381 cgtatcagtg gtgtgccaat tgttgaaact ttagcaaacc gtaagttggt cggtatcatt
     7441 actaatcgtg atatgcgttt tatttctgat tacaatgcac caatctctga acatatgact
     7501 agtgagcacc tcgttacggc tgctgttggt acagatcttg aaactgcaga acgtattctt
     7561 catgaacacc gtattgaaaa acttcctttg gttgataata gcggtcgtct gtctggttta
     7621 atcactatca aagatattga aaaagtaatc gaattcccac atgctgctaa agatgaattt
     7681 ggtcgtcttc tggtcgctgc tgcggtaggt gttacctcag atacttttga gcgtgccgag
     7741 gccttgtttg aagctggtgc agatgcgatt gttattgaca cagctcatgg tcattcggct
     7801 ggtgttctta gaaaaattgc tgaaattcgt gctcattttc caaatcgtac tttgattgct
     7861 ggaaatattg ccactgctga aggtgcgcgt gctctttatg atgcaggtgt tgatgttgtt
     7921 aaagtgggta ttggtcccgg atctatctgt accactcgtg tggttgcagg tgtcggtgtt
     7981 cctcaagtga ctgctattta cgatgctgct gctgttgctc gtgaatatgg caaaacgatt
     8041 attgctgatg gtggtatcaa gtattctggc gatattgtta aggctcttgc agccggtggt
     8101 aatgctgtta tgcttggatc aatgtttgca ggtactgatg aagctccagg tgaaactgaa
     8161 atctaccaag gccgtaagtt caaaacttat cgtggaatgg gttccattgc agctatgaag
     8221 aaaggatcaa gcgatcgtta cttccaaggt tccgtaaatg aagctaataa actagttcca
     8281 gaaggtattg aaggccgtgt tgcttataaa ggagctgctt cagatattgt cttccaaatg
     8341 ttaggtggta tccgctcagg tatgggttat gttggcgcag gtgacattca agaattacat
     8401 gaaaatgctc aatttgttga aatgtcaggt gcaggcttga ttgaaagtca tccacatgat
     8461 gtccaaatca caaatgaagc accaaactat tctgtgcact gataatttaa tttagtaact
     8521 ttaagggctg acatattgtg ccagctcttt tttatattaa aaaacgataa aatataataa
     8581 taattttcgg ataactttta ttgttttttc tta
//
LOCUS       DAUGSW010000045         8574 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUGSW010000045 DAUGSW010000000
VERSION     DAUGSW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8574
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.045"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            67..693
                     /locus_tag="VIB18_001422"
     CDS             67..693
                     /locus_tag="VIB18_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8766422.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLKTLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSIKQT"
     gene            1346..1735
                     /locus_tag="VIB18_001423"
     CDS             1346..1735
                     /locus_tag="VIB18_001423"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEQ8766423.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            1829..2881
                     /locus_tag="VIB18_001424"
     CDS             1829..2881
                     /locus_tag="VIB18_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8766424.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            3020..4552
                     /locus_tag="VIB18_001425"
     CDS             3020..4552
                     /locus_tag="VIB18_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766425.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            4545..5609
                     /locus_tag="VIB18_001426"
     CDS             4545..5609
                     /locus_tag="VIB18_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766426.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            5611..6567
                     /locus_tag="VIB18_001427"
     CDS             5611..6567
                     /locus_tag="VIB18_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766427.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(6780..8498)
                     /locus_tag="VIB18_001428"
     CDS             complement(6780..8498)
                     /locus_tag="VIB18_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8766428.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKSKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFETLRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSAGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
BASE COUNT         2633 a         1397 c         1747 g         2797 t
ORIGIN      
        1 tatttgtaat atagataaaa ttgttaaaaa acaagcgtct tgtaaaccat ttcaaagtat
       61 gatagaatga aaaagtacct taaaaagata ggaaaaatga tgacaaagat gtattatgat
      121 gaaaatccag atagcctaca cgatattcat gaagtaaaag tagagctgct taatcatccc
      181 tttacttttt tgacggattc aggtgtcttt tcaaagaaaa tggttgattt cggtagccaa
      241 gtattattaa agacactaaa tttcaaggag aacgaacgtg tactggactt aggttgcggc
      301 tatggccctc ttgggattag tctagccaag gttcaaaggg tagacgcaac cttagtggac
      361 atcaataatc gtgctcttga tttagctaga aaaaatgcaa ctaataacca agtggcagta
      421 actatttttc aatcaaatat ttatgaaaat attagtggcc attttgagca tattattagt
      481 aatcctccta ttagagcagg aaagagagta gttcatagta ttattgaaaa aagcatagat
      541 tttttagtgg ttaatggtga cttaacgatt gtgattcaaa aaaaacaagg agctcctagc
      601 gctaaagcaa aaatggcaac tatttttggt aatgttgaga tattaaggaa agataaaggt
      661 tattatgtat taagaagtat aaagcaaacc taatttaaat aatcaacaat tgctcattta
      721 aattaggttt gcttaaatag taaagagtta tttttaaatt acagataact aatattatac
      781 tagggtagcc cctctactcg agtaaccttt tttaatgtat tttaactgaa aaaggctttc
      841 ataattttaa aaaaatgtta aaataggtgt ataacaactg attaccaaga gattattatc
      901 attatcttct aaggtgtcat tgttatggtg acaatcaacc atacgctact aaagataggt
      961 agcgttcgat cacaggttga tcaagtgatt gaaaagtcaa tatttataat tttacaaata
     1021 tctgtatcaa tccatgttga atagtctatg cttctaaggt gtcgacgtta atgtactgac
     1081 gggaccgtta tagtctttct ttttggagaa acgtcggatg ccagtgaact agttgaagtt
     1141 aaagatgtta attcaaacag tgctgaagag attgatatcg ttttgaacgg tcgtttactt
     1201 caaagcaaag aaattaccag tctatcggag atgatataag tgctaaagtt agatcacgtt
     1261 aattatctat caagtcgggt gcatatttcg ttaaagtatc tacaggggtt tcaatagatg
     1321 tagctattat gaaaggtgat gttaaatggg gactactgat ttagttagtt gtgctgtaca
     1381 agctagtgag tatgcttatg tcccttactc tcattttcca gtaggagcag ctttaaaaac
     1441 aaaagatgga acgatctata ctggctgtaa tattgaaaat gttagttttg gtctgacaaa
     1501 ttgtggagag cgaacagcta tatttaaagc catatctgat ggtcataaag aattggttga
     1561 aattgctatt tatggagaaa ctatgcaacc tgtatctcct tgtggggctt gtcgtcaggt
     1621 aatggcagaa ttttttgatc cttcttcttt agtcacttta attgctaaaa atggtcaaac
     1681 tgttgaaatg actgttggag atttactccc ctattctttt acagatttaa tataatctgc
     1741 tttaatttct gttatctagc cgtcttggct ttatatttac tttcagcaac ttatttgcta
     1801 gaaatctttt ttaggagggt tcatattcat gaacaagaaa tttattggtc ttggtttagc
     1861 gtcagtggct gtgctgagtt tagctgcttg tggtaatcgt ggtgcttcta aaggtggggc
     1921 atcaggaaaa actgatttaa aagttgcaat ggttaccgat actggtggtg tagatgacaa
     1981 atcattcaac caatcagcat gggaaggcct gcaatcttgg ggtaaagaaa tgggccttca
     2041 aaaaggaaca ggtttcgatt attttcaatc tacaagtgaa tctgagtatg caactaatct
     2101 cgatacagca gtttcaggag ggtatcaact gatttatggt atcggctttg cattgaaaga
     2161 tgctattgct aaagcagctg gagataatga aggagttaag tttgttatta tcgatgatat
     2221 tatcgaagga aaagataatg tagccagtgt tacctttgcc gaccatgaag ctgcttatct
     2281 tgcaggaatt gcagctgcaa aaacaacaaa aacaaaaaca gttggtttcg tgggcggtat
     2341 ggaaggaact gtcataactc gatttgaaaa aggttttgaa gcaggagtta agtctgttga
     2401 cgatacaatc caagttaaag ttgattatgc tggatcattt ggtgacgctg caaaaggaaa
     2461 aacaatcgca gcagctcagt atgcagcagg tgctgatgtt atttaccagg cagcaggagg
     2521 cactggagca ggtgtattta atgaagcaaa agctattaat gaaaaacgta gtgaagctga
     2581 taaagtttgg gttattggtg ttgaccgtga tcaaaaagac gaaggaaaat acacttctaa
     2641 agatggcaaa gaagcaaact ttgtacttgc atcatcaatc aaagaagttg gtaaagctgt
     2701 tcagttaatc aacaagcaag tagcagataa aaaattccct ggaggaaaaa caactgtcta
     2761 tggtctaaaa gatggcggtg ttgaaatcgc aactacaaat gtttcaaaag aagctgttaa
     2821 agctattaaa gaagcgaaag caaaaattaa atctggtgac attaaagttc ctgaaaaata
     2881 gtgtttaaga acaagaagcg cgacctttgt cggtcgctct ttttaaactg agataatttt
     2941 tatctcagta aagtttgtga taggtgatag atcataggct ttactgaaat aaaagattgc
     3001 attgaaagga aatgatccta tgacacagca tgtcattgaa atgagagaaa tcacgaaaaa
     3061 atttggtgat tttgttgcaa atgaccacat taacttaaat gtcagaaaag gtgagattca
     3121 tgccttattg ggtgaaaatg gggcaggtaa atcaactttg atgaatatgc tagctggtct
     3181 cttagagcct actagtggag aaattgtcat taatgacaag ccagttcaaa ttgattcgcc
     3241 atctaaatca gctaagcttg gtatcggaat ggtacatcaa catttcatgt tagtagaagc
     3301 cttcacggtt gctgagaata ttattttagg aaatgaagta gtaaaaaatg gatgcttaga
     3361 tcttaaccaa gcatcaaaag atattaaggt actatccgaa aaatatggcc ttgcaatcaa
     3421 tccatcagct aaagtttctg atatttcagt aggagcacaa caacgtgttg agattttgaa
     3481 aaccttgtat cgtggtgcag atattcttat ctttgatgag ccaactgccg ttttaacacc
     3541 tgcagaaatt aaagaattga tgactatcat gaagaatctc gtgaaagaag gaaaatcaat
     3601 tattttaatt acccataaac tggacgagat tcgtgctgtc gccgaccgtg tcacagttat
     3661 tcgtcgtggt aagagtatcg aaacagttga tgtggcagga gcaacttcac aagatttagc
     3721 tgagatgatg gtgggacgct cggtttcctt tacaactagc aaaaaagctg ctgaaccaaa
     3781 agatgtggtc ttatccatca aaaatcttga agtagatgaa aatagaggga ttccagcagt
     3841 taaggggcta tctctagatg tccgagctgg tgaaattgta gggattgctg gaattgacgg
     3901 aaatggtcaa tctgagttaa ttcaagctat tacaggttta cgtaaagtca aatctggaag
     3961 tattatgatt aaaaacaatg aagtcactca tttgtcttca cgcaaaatta ctgagttatc
     4021 agtgggtcac gtgccagaag atcgtcatcg agatggtttg atactagatc tttctttagc
     4081 tgaaaataca gccttacaaa cctattacaa acaacctcta agtcaaaatg gaatcttaaa
     4141 ttatactaaa attaatgact atgctcgtca attaatgaaa gaatttgatg ttcgcggagc
     4201 caatgagcta gtaccagcta gaggattttc tggtggtaac caacaaaagg ccattattgc
     4261 tcgtgaagtg gaccgtgatc cagatttact tattgttagc caaccaacac gtggtcttga
     4321 cgtaggagct attgaatata tccataagcg tttgattaaa gaacgtgata aaggtaaagc
     4381 tgtcctcgtt gttagttttg aacttgatga aatattgaat ttatctgatc gaattgctgt
     4441 tattcatgat ggtaaaattc aaggtatcgt attgccagaa aataccaata aacaagaatt
     4501 gggtatttta atggcaggtg gttcaattca taaggaggaa ggtcatgtct aaaaatgcgc
     4561 aaaaaattgc tgtaccattg atttctgtct tgctaggatt tttacttggc gctattatta
     4621 tggttatctt tggttatgat cctatctggg ggtatgaagg tttattccaa attgcctttg
     4681 gtagtgttaa aaacattgga gaaatattcc gttcaatggg gccattgatt ttaatagcgc
     4741 ttggctttac tgttgctagc cgtgcaggct tctttaacgt tggtttgtct ggacaggctt
     4801 tagctggatg gatttcagca ggttggtttg cactcttaaa tccagatatg cctcgtccat
     4861 tattgattct tatgacagct cttatcggaa tgattgctgg tggtattgct ggagctattc
     4921 cagggatact tcgtgcttat cttggtacaa gtgaagttat cgttacgatt atgatgaact
     4981 acatcatttt atatgtcgga aatgctattg ttcaacgtgg ttatcctgag agtgtcaaac
     5041 aaagtattga ttcaactatt caagttagtg ataatgctag ttatcaaacg cattggttat
     5101 cagccctaac taataactct cgtattaata ttggtatttt ctttgccatt attgccattg
     5161 ccctaatctg gttcttgctt aacaaaacta ctttaggttt tgagattcgt tcagttggtc
     5221 tcaacccaca tgcttcagaa tacgcaggga tgtcatcaaa acgtactatc attttatcaa
     5281 tgattatctc tggagctctt gcaggtcttg gaggagtagt tgaaggtcta ggaacctttg
     5341 aaaatgtttt tgtacaagga tcttctttag cagttggttt tgacggtatg gcagttagct
     5401 tattagcagc aaattcaccg cttggaatat ttttctcatc attcctattt ggtgtcttaa
     5461 atattggtgc tccaggaatg aatattgcag gcattccacc agaacttgtt aaagtagtaa
     5521 ctgcatcaat cattttcttt gttggttcac attacctcat tgaacgttac attattcgcc
     5581 ctaaaaaatt agtgaaaggt ggtaaataag atgagtttag taacaatttt tgccttattg
     5641 gtgtcatcta tgcttattta tgcaacacca ctcattttca caagtattgg aggaactttc
     5701 tcagagcgct caggcgttgt taatgttggt ttagaaggta tcatggtcat gggagcgttc
     5761 tctgggattg ttttcaactt agagtttgct gaaacatttg gaaaagcaac gccttggata
     5821 gccgttttag tcggtggtat tgttggtttg attttttctt tgattcacgc tgtagcaacc
     5881 atcaactttc gagctgacca cattgtcagt ggtacagtgt tgaacttgtt agcaccttct
     5941 tttgctgtct tcttggttaa agctatgtac ggtaagggac aaacagacaa cattcaacaa
     6001 tcttttggga agtttgattt cccaggttta tcacaaattc ctgtgattgg tgatattttc
     6061 tttaaaaata ctagccttat tggttacttc gccattgctt tttcgttctt tgcttggttt
     6121 ttgctttata aaaccaggtt tggtctgcgt ttacgatcag ttggggaaca ccctcaggca
     6181 gctgacacac ttggtattaa cgtctatttg atgaaatact atggtgtgat gatctcaggt
     6241 tttcttggtg gaataggtgg agctgtttat gctcagtcaa tctccgttaa ctttgctgta
     6301 acaactatct taggtcctgg atttattgct ttggcagcta tgatctttgg taaatggaat
     6361 ccagttggcg ccatgctatc tagtcttttc tttggcttat cgcaaagttt agccgttatt
     6421 ggtgctcaat taccattact agaaaagatt ccaacggttt acttacagat tgcaccttat
     6481 atggtaacga ttattatttt agctgctttc tttggtcaag cagttgcacc aaaagctgat
     6541 ggaatcaact atattaaatc taaataacgt tatattagta agcctcttag tgaggtttaa
     6601 cagcactcct aaagcaagat agttaggtct agctttaagg gtgctttttt gggacttacc
     6661 gcaagtttgg attgccagtc accatcacaa tagaagcaag aatagactaa aaagaactaa
     6721 gtcagcggct tagttctttt tgcttgtctt ttgtttttac tgatagctct taagttgttt
     6781 tagccaacaa aggtattgat ttctgtttca atgttagcaa ttttttcttg agcgatgtca
     6841 agagtatcac ctattgtggc aatatagaac ttgatttttg gttcagttcc tgaagggcga
     6901 actgcaatcc atgaatcatc agctaacgtg tacttcaaaa cattacttgg aggagttgtt
     6961 aagttagata ttgttccatc atttttagta gcggtttgtt tttggaaatc ttctaataat
     7021 acaatatcag tattgttaaa ttgttttgga ccattttcac ggaatttgtc cataatcttc
     7081 ttaatttcag cagctccatc cacacctgaa agtgttactg aaatcgtttt ttcagcaaaa
     7141 tagccatatt ctttgtaaat ttcatcaata ccatctgcaa gtgttaaacc acgcgaacgg
     7201 taataagctg cgatctcagc aaccaaaaga actgcttgaa tagcgtcttt atcacggaca
     7261 aatggtttaa taagatatcc gaagctttct tcaaaaccaa acatataggt gtggttatgt
     7321 ttttcttcaa actcttgaat tttctcagcg atgaatttga atccagttaa aacgttaaac
     7381 attgtagcgc cataactttc ggcaattttt gttactaatt ctgttgatac gattgattta
     7441 gcgagagcag cattttctgg aagtgttcct gctgttttat gagcttccag gatgtatttc
     7501 gcaataatcg ctccaatttg atttccagaa agatttttat aagaaccatc tggttggcga
     7561 atttcaacgc ctaggcggtc tgcatcagga tcggtagcta ctaagacatc tgcatcaact
     7621 tctcgtccga gttcttcagc aagagcaaag gcagcttggc tttcagggtt aggcgattta
     7681 acagtagaaa agtctggatc tgccttagct tgtgattcta ctacaacaac agattcaaaa
     7741 ccggcttgag caagggcacg gcgtgtcaac atctcaccag ttccgtggag aggagtatag
     7801 acaattttca tgtcttttcc aaagttattg attaaatctt gattgatatt aacatcttta
     7861 acctctctaa gatattccat atcaacatct tcaccgataa cttgaataag acctgctgat
     7921 ttgctttcat ctaaatcagc aagttcaact gcaaatggat tttcaatagc acggataaag
     7981 tctgttagtg catcagcatc agctggtggt agttgacctc cgtcttgtcc atagacttta
     8041 taaccattga aaggtgctgg attgtggctt gcagtaacca taataccagc ataggcattt
     8101 aaatggcgaa cagcaaaaga aagttctggt gttggacgaa gagtttcaaa tacgtaagat
     8161 ttaattccat gctgtgccaa gacctgtgca gattcaaaag caaattctgg agagaagtgg
     8221 cgcgaatcat aagcgatggc tacaccacgt tttttagctt cctctccctt agtttcgatt
     8281 aattttgcta atccttcggt tgcttgacgg acaacataaa tattaatacg atttgtacca
     8341 gcaccaatat aaccacgcat accagcagta ccaaattcta agtttgtgta aaaagcatct
     8401 tcttttgatt tttcatccat tgatagtaat tcttgacgaa gatagtcagg aagctgctca
     8461 aaatctaacc atttttgaaa attttctgtg taagtcattg aaatactcct tcaatattta
     8521 taaacgcttt cattatatca ttttgaagga aaaaaaacac taattatttg cagc
//
LOCUS       DAUGSW010000046         8398 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUGSW010000046 DAUGSW010000000
VERSION     DAUGSW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8398
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.046"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            229..927
                     /locus_tag="VIB18_001429"
     CDS             229..927
                     /locus_tag="VIB18_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8766429.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            complement(1044..2606)
                     /gene="ffh"
                     /locus_tag="VIB18_001430"
     CDS             complement(1044..2606)
                     /gene="ffh"
                     /locus_tag="VIB18_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEQ8766430.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGVKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(2621..2962)
                     /locus_tag="VIB18_001431"
     CDS             complement(2621..2962)
                     /locus_tag="VIB18_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEQ8766431.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            complement(3051..3749)
                     /locus_tag="VIB18_001432"
     CDS             complement(3051..3749)
                     /locus_tag="VIB18_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8766432.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            complement(3832..5265)
                     /locus_tag="VIB18_001433"
     CDS             complement(3832..5265)
                     /locus_tag="VIB18_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766433.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKKPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            5432..6994
                     /gene="guaA"
                     /locus_tag="VIB18_001434"
     CDS             5432..6994
                     /gene="guaA"
                     /locus_tag="VIB18_001434"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEQ8766434.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSDTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            complement(7036..8259)
                     /locus_tag="VIB18_001435"
     CDS             complement(7036..8259)
                     /locus_tag="VIB18_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8766435.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
BASE COUNT         2513 a         1593 c         1488 g         2804 t
ORIGIN      
        1 ttgtttagct cagaactaaa tgataatttt atctttaaag taattaactc tttatcagat
       61 atagacctgc tagtacacga atctagtcgc tatgttatgt tttaggtgtt cccccttttt
      121 gacagtgtta ctatcacatg aattaattgt aggaaatgtt acacttgctt tcgttttatt
      181 tttttgatac tattagtaaa gttataactt tactaaagga gctaccaaat gttttctgga
      241 catcaactaa aaacagcacg attatcaaag ggaataactc aatcagaatt gggaagattg
      301 ttgcatgtca ataaaatgac aatatctaat tgggaaaaag gtaagaatat accaaatgaa
      361 aaacatttaa atgccttatt gcatctattc aatgtgacat ctgattattt cgacccaaac
      421 tatagattgc taacgcctta taaccagctg acaatatcta ataaagaaaa agtaattggc
      481 tattcagagc gattgttaaa tcatcaaata gacaaaaaat ctaaagatct catagataaa
      541 ccatcacaat tatatgctta tcgggtctat gaaagtttat ctgctggtac tggttactcc
      601 tattttggtg atggtaactt tgatgttgtc ttttacgatg aacaattaga atacgatttt
      661 gcgtcttggg tttttggaga ttctatggag ccaacttatt taaatggtga agttgttctt
      721 ataaaacaaa atagttttga ttacgatgga gcaatttatg cagtcgaatg ggatgggcaa
      781 acatatatca aaaaggtatt tcgtgaagat gagggattac gtctagtgtc cttaaataaa
      841 aaatattctg ataagtttgc tccctatagc gaagaacctc gcattattgg caaaattatc
      901 gctaatttta ggcccttaga aatttgagtt agattgataa tgaacccatc atggtatgta
      961 acacggtctt ccgtaatttt aataatcttg tatacaagat aaatgaattt cacatcaaaa
     1021 agagacgaaa attttcgtct cttttatttt cgttttttct ttgctttttt tagtttgtta
     1081 gcctgccgtt tcatggcctg tttcatggca aattggccaa tttttccttt aaccccttta
     1141 ccaaatagtt gactcatatc catatcacca ccaaggccag ataaatcagg cataccacct
     1201 tgtcccatca tcccttctaa ggaagacata tctggcatac cagcaggcat gtttttagga
     1261 agattattgg gattaatgcc catatctttc atcatcttag acatatcgcc cgacataacc
     1321 ccttgcatca tgcttttggc ttggttaaag tctttgataa atttattaac ttccacaaag
     1381 ctgttcccgg aaccagctgc aatacgacgg cgacgactcg ggtttagtaa gtcaggattt
     1441 tcacgttcag cgggtgtcat tgaagagaca atagcacgtt tgcgagcaat ttggttttcg
     1501 tcaactttga tattggccaa agctgggtta ccagccattc ctggaatcat tttcaagagg
     1561 tcttccatag gccccatatt ttgcacttga tctaactgtt caataaaatc attgaaatca
     1621 aaggtgtttt cacgcatttt ctcagctaac tctaaggatt ttttctcatc atattcctgg
     1681 ctagcttttt caataagagt gagtaagtca cccattccca aaatccgact ggacatgcgg
     1741 tctgggtgaa atgtttcaat atctgtgatt ttttcaccaa tacctgtaaa tttaattggt
     1801 ttcccagtga tttcacggac agatagcgcc gcacctccac gggtatcacc atcaatcttt
     1861 gttaacacaa cccctgtgat gctcaactga tgattaaact cgtaggctac attggcagct
     1921 tcttgaccaa tcatgctatc tacaaccaaa agaatttcat ttggttgtgc taaagccttg
     1981 acatcgcgca gctcttccat cagtttttca tcaatttgca agcgacccgc agtatcaatc
     2041 aagacatagt cattacggtt ttcgcgagct tgttccaaac cttttctgac aatatcgact
     2101 gctgagtggt ctgtccccat atcaaaaaca ggtacattga tttgttgccc cagtgttttt
     2161 aactgatcaa tggccgctgg acggtaaata tcggcagcaa tcatcagtgg tcgcgcgttt
     2221 tcttctttaa ttaatttatt agcgagtttt cctgcaaaag ttgttttacc agccccttgc
     2281 aaaccgacca tcatgataat agttggaatt ttgggagatt tatcaatctc tgcagtttct
     2341 gagcctaaaa tactcgttaa ttcttcatta acaatcttaa gaatttgttg tgttggatca
     2401 agagtatcaa taatctcatg gccaatagcg cgctcacgta cgcgcttaat aaaggtttta
     2461 acaactggta aagcgacatc ggcttctaaa agagctagac gaatctcttt tgtcacttct
     2521 tgaacatctg attctgataa tttcttttta ccgcgaatgt gtttaaacac atcttgcaaa
     2581 cgttgggtta agctttcaaa agccatagtc aaaactcctc ttactctcta ttgtcaatac
     2641 tggttagaat ggaaattttt tcttgcaaat actcatcatg agggtagtga gcaatcatgt
     2701 cgtcaaagat ttcacttcga acaacataat ccgaatacat atgaagtttc atctcataag
     2761 tctctaaaat tttttccgta cgcttaatat tatcatagac agcctgacga ctgacaccaa
     2821 attcatcagc aatctcagct aagctataat catcggcata atacagttca atataattca
     2881 tttgtttatc tgttagcaaa gctgcataaa attcaaaaag ggcattcatc ctgtttgttt
     2941 tttcaatttc cataatgttc attttatcat actatgattg tttttaacag tagcaaatta
     3001 attgccttgt gctgttcgtg taaaaaaaga agtcataaat gacttcttta ctaattattt
     3061 tctaagtaaa attcaaaacg gtcaccgata tactgactgc ggacatactc aaaaggtttg
     3121 ccgtctgtaa agtaagacac ctgagttaga gccaaaatgg catgtccttt agcaacttcc
     3181 aagtaggagg ctacacgctc acttgctagc ttagcgtaga ttgtctgttt acttttacca
     3241 atctcgtaac catttgctat caatgagtga aaaaagtgtt ctgtaatatc agctcgttta
     3301 accgttttta taaatttttc tgggattgaa gcaatttcgt acaccaaagg gacactgtct
     3361 gcatagcgga tacgttccat tcgaatgacc aagtctgttt tgtctaagtt caattcttta
     3421 acttcggtat cactagctaa ttgcttttga taggataata atttagagga gggttgtcgt
     3481 ccttgggagc gtataatttc tgtgaaactt gttgttcctc gcattttttc ttgaacacga
     3541 tgactggcaa cataagtacc acttcctatc cgcctttcaa gaatcccttc ttctactagt
     3601 aatgtaatag cctgccgtag agtcattcga ctaacggtga aatgttccgc taaatgtcgt
     3661 tcacttggta agcgactacc aattggccag atgcccagat caatgtcttt tttaattgca
     3721 tcatgaattt ttatataagc tggtaacatg ccacactcct caagtcggtt attcatctat
     3781 tttatcatat ttttgatgaa aattgaattg taaatattga ggtatttggc atcaattaat
     3841 gatattacct gcgacaataa ctggtgaatt tggtggaaaa tgaataggtt ccataaacca
     3901 actagtgagc ttcgctttag taacaatgga tgaggtaaaa acattattta aaaccctaat
     3961 aactcctact tttgaggaat gctgaccaat agaaccacta taggctctca ggcaaccagt
     4021 cggatctata taaggtaaaa attgattttg gcttacagta atattgtgac atagatgtcg
     4081 agtttggtta aatgcttcat agtttggagc aatattacta agtagacctc catcccatgc
     4141 aaaatgatga acagcagcat caaactgaat gacttctgaa aaaaaatcat gcccttgagc
     4201 ctttgatagc agctgttggt cttgtactaa ttctggcgca tagccaataa attggttttt
     4261 ctcaaacaat gaattttgta gagatcctaa atcaaaaata tgactattac gcttatgaac
     4321 catagtaaat ttgttatcgt aaatatgcca atcagtacca tgatcagcca taatcataaa
     4381 gtggtctcct tttttcaaat catttgcttt gaaatgcact ccagtcaaca cgagattacg
     4441 aacaccttgt tcagcctttg gtcctgtagg gaatccaaac cacaacattt taccgtgaat
     4501 aatgaactct gtctgatgac caataatagc tgtatcagat ggaagctcaa aataatcttt
     4561 ttgtgaaggc aaagagccaa tgtgaaattg cccctttgga aaagatataa cgctatttgg
     4621 atgctgcttt gcataggcga aagcttttcg caaaagacga ttgttttgct caggggaatt
     4681 tcctttattg aacctaatat aataaggttt aacaaaatct tgctctgaaa ttccatctaa
     4741 tcttagatta tctttcaggt taatatcgta ctgatatcct cctaacgaat agtcatagcg
     4801 ttttttaact tgtttaatag tcgctaattg accttgatac acttttatat gtggcttttt
     4861 agttaatgaa gataatttaa cgatatctcc ttttttaaac ctcggtttat caggcttttt
     4921 caggttatgt tctggcaaag aaacagtgac ttttcctatt ggaaatacca cttcataatg
     4981 ataactcact cggtaatttt cggctatatc ttctacctgt ttattaatag ttccaatcca
     5041 ttgatgatat ggaccacttt tttgtacttg aatagcttgt ccaatgtgat agcgaggctg
     5101 ttgatctttg cttcgttcca ctattccgac agttgctaat atattgtgaa gtgttgcaaa
     5161 actattggtc cacgcaaggt acgaaacaac taaactcaac aataatccta ggaaaattaa
     5221 ttcaacaggt cgaaataaac ccaaaattct cttttttctt agcatagacc ctccctgttg
     5281 tcttaattcc ctttcatagc ctctattgta acataacgat tacgtttttt tccaacgagc
     5341 tagagaaatt gtaatgtctt ttcgatgaaa atatgctaca ataagttgac aactatcagc
     5401 ctgacggttg gtatagaatg aaaggattat aatgactgaa atttcaattt tgaatgatgt
     5461 tcaaaaaatt atcgttcttg attatggtag ccagtacaat cagcttattg ctagacgtat
     5521 tcgagagttt ggtgttttct ccgaactaaa aagccataaa atcaccgctc aagaacttcg
     5581 tgagatcaat cccataggta tcgttttatc aggaggtcct aactctgttt acgctgataa
     5641 cgcctttggc attgaccctg aaatctttga actagggatt ccgattcttg gtatctgtta
     5701 cggtatgcaa ttaatcaccc ataaattagg tggtaaagtt gttcctgctg gacaagctgg
     5761 taatcgtgaa tacggtcagt caacccttca tcttcgtgaa acgtcaaaat tattttcaga
     5821 cacacctcaa gaacaactcg ttttgatgag ccatggtgat gctgttactg aaattccaga
     5881 aggtttccac cttgttggag actcaaatga ctgtccctat gcagctattg aaaatactga
     5941 gaaaaacctc tacggtattc agttccaccc agaagtgaga cactctgttt atggaaatga
     6001 cattcttaaa aactttgcta tatcaatttg tggcgcgcgt ggtgattggt caatggataa
     6061 ttttattgac atggaaattg ctaaaattcg tgaaactgta ggcgatcgta aagttcttct
     6121 aggtctttct ggtggagttg attcttcagt tgttggtgtt ctacttcaaa aagctatcgg
     6181 tgaccaatta acttgtattt tcgttgatca cggtcttctt cgtaaagacg agggcgatca
     6241 agttatggga atgcttgggg gcaaatttgg cctaaatatt atccgtgtgg atgcttcaaa
     6301 acgtttctta gaccttcttg cagacgttga agatcctgag aaaaaacgta aaattattgg
     6361 taatgaattt gtctatgttt ttgatgatga agccagcaaa ttaaaaggtg ttgacttcct
     6421 tgcccaagga acactttata ctgatatcat tgagtcagga acagaaactg ctcaaaccat
     6481 caaatcacat cacaatgtgg gtggtctccc cgaagacatg cagtttgaat tgattgagcc
     6541 cttaaacact cttttcaaag atgaagttcg agcgcttgga atcgctcttg gaatgcctga
     6601 agaaattgtt tggcgccaac catttccagg tcctggactt gctatccgtg tcatgggagc
     6661 aattactgaa gaaaaacttg aaaccgttcg tgaatcagac gctatccttc gtgaagaaat
     6721 tgctaaggct ggacttgatc gtgacgtgtg gcaatacttt acagttaaca caggtgtccg
     6781 ttctgtaggc gtcatgggag atggtcgtac ttatgattat accatcgcca ttcgtgctat
     6841 tacgtctatt gatggtatga cagctgactt tgctcaactt ccttgggatg tcttgaaaaa
     6901 aatctcaaca cgtatcgtaa acgaagttga ccacgttaac cgtatcgtct acgacatcac
     6961 aagtaaacca cccgcaacag ttgaatggga ataacagaat aaacattaaa agactcgctc
     7021 attttggcga gtcttttaat gtttattctt taactgtttt cgtattttgt acatggtatt
     7081 agcaatatga taaagtgggc tgacagggag attaaattct cctataaatt cttctattgt
     7141 cggagcaaag ttggccttaa atttggtaag tccatcatca agcgagcctt ctactcctcc
     7201 catgttagcc caaataatac catcttgata agcatcctga aaaacattag gatacagcag
     7261 atactgagga taaaacttct taaaatcatc attcatccca gcataaagca tttccataac
     7321 atttccataa gaaatagata atatacctgc tacaacaact tcctcaggat attggtctgt
     7381 aaagccttca aattcagtta tataacgttc taaagaagct ttttgatctt ctaatttttt
     7441 taaacgcttc ttttgatgag cttgggtgcg agtaatatct tggttaataa gaattaattg
     7501 ctggcggtat tgatctagtt tttgaggaat attcactttt gctagatgta agtaggcctt
     7561 atccccataa gtagtcatca acttttgaaa gtaagcttcg ttacgcaaag aaatattttt
     7621 acgtttttct gttaaggaga caatcttgga aaatttgtga agttctgatt gactggcacg
     7681 atatgtttct acaccacgct gcttagcatc ttttattaaa cgtctggtat gcttaggaaa
     7741 ttgcatctca aggttttctt gagtgtaaat attagcttgg aaacgaggtt ggatactatc
     7801 tgcaatctcc attgttaaac cagtccaatg aacaccagct tcttggagat tcttaatagc
     7861 tgctaaagct aaaggttttt cttcttcttc ctgtcccagt gcgtattgtt ttaacaggat
     7921 agctggatca tatttgataa agagggcctt tttagtttta ccataatcct ttagtgtttt
     7981 catggtaaat gccaccaaat cacggtcaag ataatccatg actggccctc ttggaatata
     8041 aataatgctt cttccaagtg gcaatagctt aatcaaaagt gataaagagg caacctgctt
     8101 ttcctcttta tagataccaa ttcgctcatt ctgccattga tttttgattt ttgcccaatc
     8161 actaccttgt aaaacgctaa tttgctgatg ttctttaaca aaagagtcat gctcttcttc
     8221 tgaaataccg atttttgcat aaaacgttaa attcgtcatt tattgtcccc atctattcgt
     8281 aatcttagca gatgtactta ctaagtatct tcactgtctt tatctattta ttcgtaataa
     8341 attttaaaaa aacataaaaa tagggaaact atttgaatca ctttttagta ataacgtt
//
LOCUS       DAUGSW010000047         8245 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUGSW010000047 DAUGSW010000000
VERSION     DAUGSW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8245
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.047"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(9..1058)
                     /locus_tag="VIB18_001436"
     CDS             complement(9..1058)
                     /locus_tag="VIB18_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEQ8766436.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCEDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVKPGDNVCIVGAGPVGLAALLTVQFFSPTNIIMVDLSQNRLEAAKTFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            1294..2025
                     /gene="aphA"
                     /locus_tag="VIB18_001437"
     CDS             1294..2025
                     /gene="aphA"
                     /locus_tag="VIB18_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEQ8766437.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            2203..3735
                     /locus_tag="VIB18_001438"
     CDS             2203..3735
                     /locus_tag="VIB18_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEQ8766438.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVMVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            3898..4512
                     /locus_tag="VIB18_001439"
     CDS             3898..4512
                     /locus_tag="VIB18_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEQ8766439.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQAYI"
     gene            4671..5819
                     /locus_tag="VIB18_001440"
     CDS             4671..5819
                     /locus_tag="VIB18_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8766440.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            5868..6548
                     /gene="radC"
                     /locus_tag="VIB18_001441"
     CDS             5868..6548
                     /gene="radC"
                     /locus_tag="VIB18_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEQ8766441.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(6550..7245)
                     /locus_tag="VIB18_001442"
     CDS             complement(6550..7245)
                     /locus_tag="VIB18_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEQ8766442.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(7255..7899)
                     /locus_tag="VIB18_001443"
     CDS             complement(7255..7899)
                     /locus_tag="VIB18_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEQ8766443.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(8151..>8245)
                     /locus_tag="VIB18_001444"
     CDS             complement(8151..>8245)
                     /locus_tag="VIB18_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8766444.1"
                     /translation="KTKDNQILQDKFYFLMDSLVEREIFSKTVV"
BASE COUNT         2611 a         1316 c         1552 g         2766 t
ORIGIN      
        1 ttttgtgatt agctaatatc attatcaata ataactttca aggcgttatt tgcaccagca
       61 tgtttaaagg tttcataagc tttttcaact tctgaaagtt taaaatgatg tgtaataagt
      121 cttgttgcgt caatctttcc agttttcaag acatttagta gcatttcagt tgtattggca
      181 ttaacaagtc cagtgtttaa ggtgatattt ttaatccata attcatccag gttgaaatca
      241 actggtttcc catgaacccc aacgttagca atatgcccac ctactgatat aattttttga
      301 caaatatcaa atgtcgcggg ataaccaaca cactccatgg aaatatcgac accacgtcca
      361 ttggttatat cgtcaatgat agccttaact tcttcactac ttcctgaaca aatcgtgtgt
      421 gtggctccaa atgttttagc tgcttcaagg cgattttgag ataagtcgac cataataata
      481 ttggttggag agaaaaattg aacggttagt agggctgcga gtcctactgg accggcacca
      541 acaatacaaa cattatctcc aggcttgaca tgtgatggca agacaccaat ttcatatgaa
      601 gttggtaaaa tatcagaaag catgacaagt gcctcatcat caatcgtatc aggagcatga
      661 tagagactac catctgcatg tgggatatgg acatattctg cttgtgttcc attaattaaa
      721 tggccaagaa tccaaccgcc atcttcacaa tgtgacgaaa ggcctcgttt acaataataa
      781 caggtatgac atgatgtgac gcaagaaata atcactttat ctccgatttt aaagttagta
      841 accgcatcac cgacctcctt aacaattcca attccttcat gaccaaggat tgttccttct
      901 ttacatgcgg gaacatcccc acctaagata tgcaaatcag ttccacaaat agtggttttt
      961 accaactgga cgatagcatc tgtaggcttt ataatgactg gttttggttt gtctatgagc
     1021 tgtagatttc cggttgaaag gtaagttgct gctttcatat ttaactcctt ataaggttga
     1081 gaggtaatca accaattcat ttttacacag atattataat agtttaagaa agggttttca
     1141 atatttttta aatcgattat gataattttt tagatcatct ttgttgaata acttcatcct
     1201 tattcagaac ttaaagggta ctattataag aatttgaaac cgctttactt aaaccgtgta
     1261 tttttgtaca ataatgatta aggaggtttt tagatgaaaa aagaatttac cagtatcctg
     1321 tttacagtta gtttttgtgg aatcatagca ttgcctgtcg aagctagtgg ccctaaagtt
     1381 ccttatacac aagaaggtat aacggccatt tcaaatcagg caacagtaaa attgatttct
     1441 attgctgata tcgcgagcag tttagaagga caaaaaccta taacggttag ttttgatatc
     1501 gatgatactt tgttatttac tagccaatat tttcaatacg gcaaagaata tataactcca
     1561 ggctcatttg attttttgca taaacaaaaa ttttgggact tagtcgctaa acggggagat
     1621 caggattcta ttccaaaaga gtatgcaaag caactaatcg caatgcatca aaaacgagga
     1681 gacaaaattg tctttattac tggccgaact cgaggatcga tgtataaaaa aggtgagatt
     1741 gataaaacag ctaagtcact ggctaaagat tttaagttag acaagccaat agctatcaat
     1801 tatacaggag ataaagctgt gaagccgtat cagtatgata aaacatatta tataaagaaa
     1861 aacggctcac aaattcatta cggagatagt gatgaagata taaatgctgc caaagaggca
     1921 ggtgcaagac ctattcgcat tttaagagct cctaattcaa ctaatcttcc tttgccaaaa
     1981 gctggaggat acggagaaga ggttttagaa aattcggctt attagtcaaa tatttgtgta
     2041 agaaaggaag taacagtaat ttctttcatc accccactga gtaaccaata gcccagtggg
     2101 ttttttgggt tacagaaatc agttctaaaa aagaatcact ggtaacttaa ggttgacttt
     2161 gatacaatgg taacagtgta tttaaaagaa agagaggaca acatggaaaa ccataaaaat
     2221 gaattcacct tttccaacaa atcaattatt gcctatgttt ggcgtggtgt tatggttggt
     2281 attattgctg gtgttattgt tagtttattc cggttgttaa ttgaagtgac agctgactgg
     2341 gtgattgaat ggtaccgata tgctcatatc aattcgctgt tgctacttcc tatactaagt
     2401 gtcagtttgt tagctgttct ttttgtaggt tttttagtaa agtctgattc tgatataaaa
     2461 ggatcaggga tcccccatgt cgaaggagaa ctaaaggggc taatgtcccc agattggtgg
     2521 agtgtccttt ggaaaaaatt tttaggagga atcatggcta tttctatggg atttatgctc
     2581 ggtcgtgagg gtccttcgat tcagttaggt gctatgtcag ccaaaggatt agctaagttt
     2641 ttaaaatcga gtcgtttgga aaagcgagtg ctaattgcca gcggagcagc agcagggcta
     2701 tcagcagctt ttaatgctcc aatagcaggc ctcttgtttg ttgttgaaga aatttaccat
     2761 catttttcgc gtttaatttg gattacagcg ctagtggcta gcttagtggc taattttatt
     2821 tctctgaata tttttggatt gaaaccagtc ttagcaatgt cagaggcgat gcctttttta
     2881 ggactcaatc aatattggtt gttgctttta cttggattat ttctaggctg cttaggctat
     2941 ttatatgaga tagttatcct taattttaat aaactttatg ttattttagg gagttggtta
     3001 catctgccag cttattttta cggtattatt atggtttttc taattttacc gattggctat
     3061 tatttaccac agttacttgg aggaggacat ggtttaatac tttctttatc caatcaacaa
     3121 ttgcctttga tgactatctt cttttatttt attattcgat ttattgttag tatgtttagt
     3181 tatggaagtg gcttacctgg aggtattttt ttacctattt taactttagg tgctttggca
     3241 ggcctattat ttgggcaaat agcttctcaa ttaggtttat tgaaccaatc ttttctttct
     3301 ctttttttga tattagggat ggcagggtat tttgcggcaa tttcaaaagc accactgaca
     3361 ggcatgattt tggtaactga aatggtaggt gatttgaaac ccttaatggc catagctgta
     3421 gttacttttg tctcctattt agtgatggat ttgttaaatg gacagccaat ttacgaagct
     3481 atgctagata agatggcaat gaagcatcca actaatcttg ttgaaccaac attaattgaa
     3541 ttgactgttg gtgataagat tgcagggaaa tatgttaaag agttaaagct tccagaaaat
     3601 gtcttaatta caacccaaat tcaccatcaa aaatctcaag ttgtgtcagg taacacgcgc
     3661 cttttatcag gagcaactat ctttttggtc gttaatgaag ctgatacagg ttttgtccgt
     3721 gaggtattga tgtaggtatt aatttatcac aattcggaaa gttcgagctt gtcttttaga
     3781 ctaagtcttc gaacgtttta ctgctagagt ttcatctgaa ccaaagtgaa acgcttttga
     3841 tgaagtcaag taggcttttt gttatactaa caataaagat aagctaagga ggctgagatg
     3901 ttagaaattg tttcagaaga gctacgtcac tatcaagaac aaaaattgat tgagtaccgt
     3961 aacaaaaatc agttagcccc aaaaggaggc attgtatttg caggtgattc tctcattgaa
     4021 ttttttcctt taaaaaaagc ttttggttca tgtttgccta ttattaatcg aggtattgct
     4081 gggatagata gtcagtggtt attgcgccat ttttctgtcc aaattactga tttagagcct
     4141 aaacatattt ttttattaat tggttgtaat gatatcgggc ttggatatga taaatgtcat
     4201 attgtcaaga ctattgtaga gcttattagc cagattcgta gtcattgtgt ctacagtcag
     4261 atttatctct tatctttatt accagtttcc aacaatcccc gatatcagaa gactgtcaaa
     4321 ataagaacaa atgctatgat tgatgctatt aataaagatt tagcaatgat tccaactata
     4381 gaatttatta atcttaatac ttgtcttaaa gacgaaaaag gtggtttatc agatgagaat
     4441 actctagatg gtttacatct taattttcca gcttatgcta aactagctga aattattcaa
     4501 gcttatatct agcaaataaa tgtactaata gcgatgaggc aagaagtcag atagcagatg
     4561 gttcatcaat caattaagaa aaaagttatc aagataccat taaaaatagt tgctcaaagt
     4621 tctttcaaat caaaagatta tgatatcgct atgttgagtt ttagtgtata atgataatta
     4681 aaggagttac catgaaattt gaaaaaaaac aagtcttcta tttagtcctt acgtttatct
     4741 tatgctatgg gatcctagca aactggcgaa atggaacggc tatcgttacg actatttaca
     4801 aaacaagcct tccttttttt tatggagcag caggtgccta tattgttaat attgtaatga
     4861 gcgcttacga aaaggtatat gtttatatct ttaaagactg gtcacatgtc ttaaaagtaa
     4921 aacggggtat ttgtttactg ttagcgtatt tgacattttt tattttaatt acttggatta
     4981 tttccattgt cattccagac ttaattacaa gtattagtac tctaacaaaa tttgatacta
     5041 taacgataca agaagttgtt aacaatcttg agcacaataa actgttagca cgtactattc
     5101 agtatattgg tggcgatggc aaacttacag agacgattgc taactatagt caacagttat
     5161 taaagcaatt tcttactgtt ttgacaaata ttttaacatc tgtcacggtt attgcttctg
     5221 caattattaa tctttttatt agttttgttt tttcgttata cgttttagca agtaaagaag
     5281 atctttgtcg tcagggaaat actttagtag atacttatac tggtaagtac gctaaacgca
     5341 ttcattactt gttagagttg ttgcatcagc gttttcacgg attttttgtt agtcagacct
     5401 tagaagctat gattttaggt tcgctgactg ctagtggcat gtttatatta agattaccat
     5461 ttgcagggac tattggcgtt ttagtagctt ttacagcatt gattccagtt ataggtgctt
     5521 caattggagc agctattgga tttattttaa ttatgactca gtccatgtca caggccatta
     5581 tttttatcat ttttttaatt attttgcagc agattgaagg caattttatt tatccgaaag
     5641 tagttggtgg atcgattgga ttaccggcta tgtgggtatt aatggcaatt acaataggcg
     5701 cttctttaaa gggaatagtt ggtatgatta ttgcagttcc tttagcagcg acactttatc
     5761 aagtgattaa agataatatt caaaaaagac aagctattca aaaaaaacaa gtttcctaaa
     5821 aggaacttgt ttttttgtcg aataaaaaga tggaggtaat atgataaatg tattctataa
     5881 aatgtgatga taataaagcc atgccaagag aacgtttgat gcgactagga gcagagtctc
     5941 taagtaatca agaattatta gcaattttat tacgaacagg taataaagaa aagcatgtct
     6001 tagagctgtc atcctatctt ttatcgcatt tagacagtct ggcagatttt aaaaagatgt
     6061 ctttgcaaga attacaacat ttggcaggta taggaaaagt taaagcgatt gaaattaaag
     6121 ctatgattga gttggtttcc cgaattttag cgacagataa gacattaact gatagcgtat
     6181 taaccagtgt tcaggtcgct gaaaaaatga tggcagcttt aggagataaa aaacaagagc
     6241 atttagtcgt attgtattta gataatcaaa atcgtattat tgaagaaaaa actattttta
     6301 ttgggactgt ccgacgttca cttgcagaac caagagaaat tttatactat gcctgtaaaa
     6361 atatggcgac tagtctcatt gttattcata atcatccttc aggaaatatt gaacctagtt
     6421 ctaacgatta ttgctttact gaaaaaataa aacgatcatg tgaagattta ggcattatct
     6481 gtctagatca cattatcgtt agctataaag attattatag ttttcgagaa aaatcaaccc
     6541 ttttttaagt cagaagtcat tgacgaataa gcggaacaat tgtagatctt catctcgaac
     6601 accttggaga agttcaggat gccactgaac acctaaaaaa ggaatggcat cgttggttga
     6661 tatgactgct tcgatggtac catcacgtgg atccctagcg attactttta aatccttagc
     6721 aacagttttt aaactttggc gatgaaaaga attaattaat gtcttatgac cataaatagg
     6781 atataagata gagtctggct caataatcat ttcgtgtgat aagaaatcag aaggcgcttc
     6841 ttgccaatgt gagtcaatgt gttggttaag atttcctcct aaggcaacat tcattaactg
     6901 tgtaccacga caaatcccta agattggttt ttttaatgtt atagcctcct tgatgatagc
     6961 tagctcaaat gtgtctcgct ctggtgaaaa atcatcatca aaagcagcct tctcttcttg
     7021 ataatatttt gggtcaacgt tttgcccacc aattaaaatg attttatcaa ccatagatac
     7081 ataagtttta gcggcggctt catcaccaat gggtaaaaga agcggcagcc ccccagattg
     7141 agtgactgcc tgtacaaatc cagtaggtgc atatgaccat gggagattat ccaaagccat
     7201 atttagtctt tgatttgcag ttattccaat aatcggtttg gtcattatac ctccttaatc
     7261 tagatgattt tgattcataa aatagagtag tgtctggagc tcactggtca aatcgacaga
     7321 ttgaacaata actcctttag gaacttgtag gtgaacagga gcaaaactca agattccttt
     7381 gattcctgct tcaataagtt gatcagtaac ttcttgagca tgaatgctgg gaaccgttaa
     7441 gatagccgtt tcaatgtcag tgttcgcaat ccgttctttg acagatgaga taccatggac
     7501 tggaatatta tcagctgttt tagtaccaac aagagcgtta tcatcggtat caaaacccat
     7561 ggcaatttgc atcttattac gatcatggaa gcggtaatgt aatagagcac gccctatatt
     7621 accgcatcca actaagataa cgtttgttgt agagtgatca ttaagcaagt cagcaaaaaa
     7681 attcatcaat ttggtaacat catagccaaa cccacgacgc cccaattctc caaaataaga
     7741 aaagtcacgg cgtacagtag cagagtcaat tcccattgca tctgcaattt gtttagaact
     7801 ggctttttca acttggtcag catggaatcg tttaaaaata cggtaataaa gtgataagcg
     7861 ctttgcagtc gcttttggaa tagatttgtc aataaccact attttactcc ttgtagattt
     7921 ctcgttaaat atgtctgtct ttattgtaac aaaaagattg tgaaaaatgc aacattttga
     7981 ttgtttttgt atgagttaaa aaagctaaaa ttagttttag cactatataa tagtattcat
     8041 taggaaagta agttatgaca gtcaaaatga acaacatgaa ttaatagcaa tagaagcgaa
     8101 atcatttatt gacattgtga tatgactaaa aaaacaaaat ttaaagttga ttagacgact
     8161 gttttgctaa aaatttcacg ttctacaagg ctgtccatca agaaataaaa tttatcttga
     8221 aggatttgat tatcttttgt tttaa
//
LOCUS       DAUGSW010000048         8003 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUGSW010000048 DAUGSW010000000
VERSION     DAUGSW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8003
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.048"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(153..938)
                     /locus_tag="VIB18_001445"
     CDS             complement(153..938)
                     /locus_tag="VIB18_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766445.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(948..1646)
                     /locus_tag="VIB18_001446"
     CDS             complement(948..1646)
                     /locus_tag="VIB18_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766446.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGVLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(1646..2017)
                     /locus_tag="VIB18_001447"
     CDS             complement(1646..2017)
                     /locus_tag="VIB18_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8766447.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            2202..5312
                     /locus_tag="VIB18_001448"
     CDS             2202..5312
                     /locus_tag="VIB18_001448"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEQ8766448.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLRELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQIYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSNYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLV
                     KIGLFDCFEPNRKKIMDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            5392..6405
                     /gene="pfkA"
                     /locus_tag="VIB18_001449"
     CDS             5392..6405
                     /gene="pfkA"
                     /locus_tag="VIB18_001449"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEQ8766449.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            6468..7970
                     /gene="pyk"
                     /locus_tag="VIB18_001450"
     CDS             6468..7970
                     /gene="pyk"
                     /locus_tag="VIB18_001450"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8766450.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICCETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
BASE COUNT         2534 a         1348 c         1657 g         2464 t
ORIGIN      
        1 cttggttctt acagcattaa ggtttggtgt taatttgata aaccgcgctt ctatttgatg
       61 gaagacggtt ttttaattta ctatgaacac tgaaaaaaac tttcttttaa actatagtgt
      121 gtcatagttt aaaagaaagt cttaacgctt acttactgta ggttgagttt atttttgata
      181 ataaaattag tggcgaggta aaacattatc atttcaataa attgttccaa aataagaaga
      241 taaattgttt tttgctcagt aaatgggaaa ctatcggcac ttgtattaat attaaagatg
      301 tgactgtgaa catatgttgc agcaacgcta atcagaataa ctaatataaa atatgcaata
      361 aaggccatca agcctcgccg attggaaaaa agttgaccta tagaaatgga aagataaatt
      421 aataagatac tcgtaaatgt tgataatagg acataggcta gtacagttag catattgatg
      481 aaataatcca tcttaaaact attaaagaat ccttctaata gttcgttgat gttaaacatt
      541 ggtacaatta caatagcgat agcaaatgca aggatgatag tattgaaaac actgcaaata
      601 aaagaagcta gtagttttga taaaataatt tgatgcgaat tgacgggtaa agtcaacgtt
      661 aagtatcctt cccgtccaaa aacacttttg ctaaaacgtt tgataatgat aagtaatgtt
      721 gataagaggg aaccagctat cagggagcca aaagttaaac ctaatgtcag aggcaacatc
      781 ttattggtta gtactccaaa tagtccatca ctattacttt gagcaaacag ttttatcgta
      841 aatgacaaaa tggcagcgat ggcaataacg aaagcattaa gcgcaaagta ccattttcca
      901 atagatctaa attcgtattt taataatttt ccaaacatga tatcctccta aaccttataa
      961 gtttccctaa agagggaatc aatggattgc tggtattctt gtcttagatc atcagcattg
     1021 ccagataaga aaagtcttcc ttgtttcaag aaaatgactt cgtcaaggat aggttcaatg
     1081 tccgaaatca agtgggttga gataataaca gaagcatttt cacaataact attaatgatg
     1141 gtttttagga tgtagtctct tgcagcaggg tcaactccac caataggttc atcaagtaca
     1201 tagagtctgg ctttacgact catcacaaga attaattgta ctttttcttt gtttcctttg
     1261 gatagagttt tgaagcggtc ttcagggtct agttctaaat ctcttagaag gcttgttgct
     1321 ttggatttgt caaagtcgct gtaaaaatca ctaaagaact ccaacatgtc cttaattctc
     1381 atattttcat tgagataagt agtatctggt aaataagaaa taattttttt tgtctcaaca
     1441 cagggacggt agccatcaat gacaatttct cctttatttg gttgtaaaac gccattaatg
     1501 agtttaatta aagttgtttt accacttcca tttggaccta ataatccgat aattttaccg
     1561 ttcgggatag taatggttaa gtcatcaata gctttttttt cacggtaaga ttttgaaaca
     1621 tgatgtagtt gcaataggtg tgccattatt gtgaatcctc ctttaaaaag ctcgtcaaaa
     1681 cagggataat ctcagtgtga ctaaatccca tttttgtcat attggtgata aatgattcta
     1741 attcactaat tgctaactct cgtcttttac gagcaattaa tttttgatcg tcagttacaa
     1801 aacggccagc agtacgttgc gaataaacca ttccttcccg ttcaagttct gtaaacgctc
     1861 gttgcatggt gttaggatta acacctgcga tttctgcata ttcacgaaca gttggaagtt
     1921 gatcaccact cttgatttct tggctaataa tttgcatcat gacatgttgt gctatctgcg
     1981 cataaatagg agatttttca tcaaatttcc aagacatgtg gtctcctttc tgagtaatat
     2041 agatatttgt actaattaaa tggtacagaa aaaaaaaggg aatgtcaagt tttatgccat
     2101 ttttcactct ttgagaagta gacgtagatt agagagaaaa ttgaagcaag aaaacctttt
     2161 tcatagtata atagggaaca agataaccaa aggaggaact tatgtttgct caacttgata
     2221 ctaaaactgt atactcattt atggatagtt taattgactt aaatcattat tttgaacgag
     2281 caaagcaatt tggttaccac accataggaa tcatggataa ggataatctt tatggtgctt
     2341 accattttat taaaggttgt caaaaaaatg gactgcagcc agttttaggt ttggaagtag
     2401 agattctcta tcaagagcgg caggtgctcc ttaacttaat cgcccagaat acacaaggct
     2461 atcatcagct tttaaaaatt tccacggcaa aaatgtctgg caagcttcat atggattacc
     2521 tctgccaaca tttggaaggg atagcggtta ttattcctag taagggttgg agcgatacat
     2581 tagtggtccc ttttgactac tatatcggtg ttgatcagta tactgattta tctcatatgg
     2641 attctaagag gcagcttata cccctaagga cagttcgtta ttttgcgcaa gatgatatgg
     2701 aaaccttgca catgttgcat gccattcgag ataacctcag tctggcagag acccctgtgg
     2761 tagaaagtga tcaagagtta gcagattgtc aacaactaac caccttctat caaacacact
     2821 gccctcaagc tctacagaat ttagaagact tagtgtcagg aatctattat gatttcgata
     2881 caaatttaaa attgcctcat tttaatagag ataagtctgc caagcaagaa ttgcaagact
     2941 tgactgaggc tggtttgaag gaaaaaggat tgtggaaaga gccttatcaa tcgcgcttac
     3001 tgcgtgaatt ggtcattatt tctgacatgg gctttgatga ttattttttg attgtgtggg
     3061 atttacttcg ctttggacgc agtaaaggct attatatggg tatgggacgt ggctcggcgg
     3121 caggtagtct agtggcttat gctctgaaca ttacagggat tgatccagtt caacatgatt
     3181 tgctatttga gcgcttttta aacaaagaac gttatagcat gcctgatatt gatatcgatc
     3241 ttccagatat ttaccgttca gaatttctac ggtatgtccg aaatcgttat ggtagcgacc
     3301 attcggcgca aattgtgacc ttttcaacct ttggccctaa acaggctatt cgtgatgttt
     3361 tcaaacggtt cggggttcca gaatacgaac tgactaatct cactaaaaaa attggtttta
     3421 aagatagctt ggctactgtc tatgaaaagt caatctcttt taggcaggtt attaatagta
     3481 gaactgaatt tcaaaaggcc tttgctattg ccaagcgtat cgaaggaaat ccaagacaaa
     3541 cgtccattca cgcagctggt attgtgatga gtgatgatac cttgaccaat catattcctc
     3601 taaaatcggg cgatgacatg atgatcaccc agtatgatgc tcatgcggtc gaagctaatg
     3661 gcctgttaaa aatggatttt ttggggttaa gaaatttgac ctttgttcaa aaaatgcaag
     3721 agaaggttgc taaagactac gggtgtcaga tcgatattgc agccattgat ttagaagacc
     3781 cgcaaacgtt ggcacttttt gctaaagggg ataccaaggg aattttccaa tttgaacaaa
     3841 atggtgctat taatctttta aaacggatta agccacaacg ttttgaagaa attgttgcca
     3901 ctaccagtct aaatagacca ggggcaagtg actataccac taatttcatt aaacgaagag
     3961 aaggacaaga aaaaattgat ttgattgatc ctgtgattgc tcccatttta gagccaactt
     4021 acggtattat gctttatcaa gaacaagtta tgcagattgc acagatttat gctggcttta
     4081 cgttaggcaa ggccgacttg ttaaggcgtg ccatgtctaa aaaaaatcta caagaaatgc
     4141 aaaaaatgga agaagacttt attgcttctg ctaagcacct agggagagct gaagaaacag
     4201 ctagaggact ttttaaacgg atggaaaaat ttgcaggtta tggttttaac cgcagccatg
     4261 cctttgccta ttcagcttta gcttttcaat tggcttattt caaagcccat tacccggctg
     4321 ttttttacga tatcatgatg aattattcta gcagtaacta tatcacagat gctctagaat
     4381 cagattttca agtagcgcaa gttaccatta atagtattcc ttacactgat aaaattgaag
     4441 ctagcaagat ttatatggga ctgaaaaata ttaaggggtt gccaagggat tttgcttatt
     4501 ggattattga gcaaagacca tttaatagcg tagaggattt tctcactaga actccagaaa
     4561 aatatcaaaa aaaggttttc cttgagcctc tggtaaaaat aggtctgttt gattgctttg
     4621 agcctaaccg taaaaaaatt atggacaatt tggatggttt actggtattt gttaatgagc
     4681 ttggttctct tttttcagat tcgtccttta gttgggtaga tacgaaagat tactcagcaa
     4741 ctgaaaaata ttctttggaa caggagatcg ttggggttgg catgagcaag catcctttaa
     4801 ttgatattgc tgagaaaagt acccaaactt ttactcccat ttcacagtta gtcaaagaaa
     4861 gcgaagcagt cgtactgatt caaatagata gcattaggat cattagaacc aaaacaagtg
     4921 ggcagcaaat ggctttttta agtgtgaatg acactaagaa aaagctcgat gtcacacttt
     4981 ttccacaaga gtatgctatt tataaagacc aattaaaaga aggagaattc tattacttaa
     5041 aaggtagaat aaaagaaaga gaccatcgac tgcagatggt gtgtcagcaa gtgcaaatgg
     5101 ctattagtca aaaatattgg ttattagttg aaaaccatca gtttgattcc caaatttctg
     5161 agattttagg tgcctttcca ggaacgactc cagttgttat tcactatcaa aaaaataagg
     5221 aaacaattgc attaactaag attcaggttc atgtaacaga gaatttaaag gaaaaacttc
     5281 gtccttttgt tctgaaaacg gtttttcgat aaaaatggac aattagtgaa gtattttgca
     5341 aatgaatgtg ctataataag accgttaaat taattaaagg agtaccagaa aatgaaacgt
     5401 attgctgttt taaccagtgg cggcgacgct cctggtatga acgctgctat tcgtgcagtc
     5461 gttcgtaaag caatttcaga aggaatggaa gtttatggta tcaaccgtgg ctatgcaggt
     5521 atggttgatg gcgacatttt cccactgggt tcaaaagaag ttggtgataa aatctcacgt
     5581 ggtggaactt tcttatactc agctcgttat ccagagtttg ctcaacttga aggtcaattg
     5641 gctggtattg agcaacttaa aaaacatggt attgaaggtg ttgttgttat tggtggggat
     5701 ggttcttatc atggcgctat gcgcttgaca gagcacggct tcccagcggt aggtatccca
     5761 ggaacaatcg ataacgatat tgcgggaact gactacacta tcggatttga tacagcagtt
     5821 aacacagctg ttgaagctat tgataaactt cgtgacacct catcaagtca cggacgtact
     5881 tttgtggttg aagtgatggg tcgcaatgcg ggtgatattg ctctttgggc aggtattgct
     5941 agtggtgctg atcaaatcat tgttccagaa gaagagtttg atattgaaaa agtggcatca
     6001 acaatccaat atgattttga acacaaaggt aaaaatcacc acattatcgt cttagctgaa
     6061 ggtgttatga gcggtgaagc ttttgctcaa aaactgaaag aagctggcga taagagtgac
     6121 cttcgtgtga caaatcttgg ccacattctt cgtgggggtt caccaactgc tcgtgaccgt
     6181 gtcattgctt cttggatggg ttcacatgct gttgagctac ttaaagaagg caaaggtggt
     6241 ttggctgttg gtattcacaa tgaagaactt gttgaaagcc caatccttgg tactgcagaa
     6301 gaaggtgctt tgttcagctt gactgaagaa ggcaagatta ttgttaataa tccacacaaa
     6361 gctcgtttag actttgcagc tttgaaccgt tcattgtcac aataagttta gttaaaattg
     6421 ttaaatcgtc aattattgac aaaaaaataa gggagtttca gagtaaaatg aataaacgcg
     6481 taaaaatcgt tgcaacactt ggtcctgcgg ttgaaatccg tggtggtaaa aaatacggag
     6541 aagatggcta ctgggctggt caacttgatg ttgaagaatc tgcaaaaaaa atcgctgaat
     6601 taattgaagc tggtgcgaat gttttccgtt tcaatttctc acatggtgac cacaaagaac
     6661 aaggtgaccg tatggcaact gtccgccttg cagaagaaat tgctcgtcaa aaagttggtt
     6721 tccttttgga tactaaaggt cctgaaatgc gtacggaatt gtttgcagat gatgctaaag
     6781 agttcagcta tgttactgga gaaaaaatcc gtgtagcgac tacacaaggt attcaatcaa
     6841 ctcgcgatgt tattgctttg aacgttgctg gtagccttga catctacgat gaagtagaag
     6901 taggtcatac tattcttatc gatgatggta aacttggttt gaaagtgatc gacaaagata
     6961 tcgcaacacg tcaatttatc gttgaagtag aaaacgacgg tattattgct aaacaaaaag
     7021 gtgttaatat ccctaacact aaaattcctt tcccagcact tgcggaacgc gacaatgctg
     7081 atatccgttt tggtcttgaa caaggactta actttattgc aatctcattt gttcgtacag
     7141 ccaaagacgt tgaggaagtt cgtgaaatct gttgcgaaac tggtaacgac catgtgcaat
     7201 tatttgctaa gattgaaaac caacaaggta tcgataatct tgatgaaatc atcgaagctg
     7261 ctgatggtat catgattgca cgtggcgaca tgggtatcga agtaccattt gaaatggttc
     7321 cagttttcca aaaaatgatt atcactaaag tgaatgcagc tggtaaagca gttatcacag
     7381 caacaaacat gcttgaaaca atgactgaaa aaccacgtgc gacacgttct gaagtatctg
     7441 acgtcttcaa tgctgttatc gatggtactg atgcaacaat gctttcagga gagtcagcta
     7501 acggtaaata cccggttgaa tctgttcgta caatggcgac tattgatcgt aatgcacaaa
     7561 ctcttcttaa cgaatatggt cgtttagatt catctgcctt tccacgtacc aataaaacag
     7621 atgttattgc ttcagctgtt aaagatgcca ctcattcaat ggacatcaaa cttgttgtga
     7681 ctattactga gacaggtaat acagctcgtg cgatttctaa attccgtcca gatgcggaca
     7741 tcttagctgt aacatttgat gaaaaagtac aacgtgcttt gatgattaac tggggtgtta
     7801 ttcctgttct tgctgaaaaa cctgcatcta ctgatgacat gtttgaagta gcagagcgtg
     7861 ttgctgtgga ggcaggctta gttcaatctg gggataatat tgttattgtt gctggtgttc
     7921 cagttggtac tggtggaacg aatactatgc gtgttcgtac agtaaaataa atgtgttata
     7981 actatttacc taaaggttag aag
//
LOCUS       DAUGSW010000049         7663 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUGSW010000049 DAUGSW010000000
VERSION     DAUGSW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7663
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.049"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            119..997
                     /gene="mvk"
                     /locus_tag="VIB18_001451"
     CDS             119..997
                     /gene="mvk"
                     /locus_tag="VIB18_001451"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEQ8766451.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLVIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            979..1923
                     /gene="mvaD"
                     /locus_tag="VIB18_001452"
     CDS             979..1923
                     /gene="mvaD"
                     /locus_tag="VIB18_001452"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEQ8766452.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTIFDEWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            1916..2929
                     /locus_tag="VIB18_001453"
     CDS             1916..2929
                     /locus_tag="VIB18_001453"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEQ8766453.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            2916..3905
                     /locus_tag="VIB18_001454"
     CDS             2916..3905
                     /locus_tag="VIB18_001454"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEQ8766454.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLFDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(4135..5412)
                     /locus_tag="VIB18_001455"
     CDS             complement(4135..5412)
                     /locus_tag="VIB18_001455"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEQ8766455.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWQFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(5399..6574)
                     /locus_tag="VIB18_001456"
     CDS             complement(5399..6574)
                     /locus_tag="VIB18_001456"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEQ8766456.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            6783..7622
                     /locus_tag="VIB18_001457"
     CDS             6783..7622
                     /locus_tag="VIB18_001457"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEQ8766457.1"
                     /translation="MTKADQIFKTNIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDRTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
BASE COUNT         2371 a         1448 c         1544 g         2300 t
ORIGIN      
        1 ttattgttaa tttcagtgaa gaaatgattt taaaaagata tatcatcgca ttttctaatc
       61 atttagtgta aaatagtaag gtaaaagttt agaagaatta gtaatgaaaa gataaaaaat
      121 gaacgaaaac attggatatg gtaaggcaca cagtaagatc attttgatag gtgagcatgc
      181 tgttgtgtat ggctacccag ctattgcttt gcctttaaca gatattgagg tggtttgtca
      241 tatttttcca gctgataagc cattggtctt tgatttttat gatactctat caacagccat
      301 ttatgctgcc ttggattatt tgcagcgact acaagaacca attgcttatg agattgtttc
      361 acaagtgcca caaaagcgtg gtatggggtc ttcggcagcc gtttctattg cagctattag
      421 agccgttttt tcttattgtc aagaacccct ctcggatgat ttgttggaaa ttttagtcaa
      481 caaggcagaa attattgccc acaccaatcc tagtggttta gatgccaaga catgccttag
      541 tgaccatgcc attaagttta tccgaaacat tggctttgaa actatcgaaa tcgccttaaa
      601 tggttatctt gtcattgcag atacagggat tcacggtcat acacgtgagg ccgtcaataa
      661 ggtagcacag tttgaggaaa cgaatttgcc ctatctggct aaactaggag ctttgacaca
      721 agcccttgaa agagcgatta accaaaaaaa taaggtggct atcggtcagc tcatgacaca
      781 agcgcactct gctttaaagg ccattggcgt tagcatcagt aaagctgacc aacttgtgga
      841 ggctgcccta agagcaggtg ctttaggcgc taagatgaca ggcggtggct tgggtggctg
      901 tatgattgcc ctagcagata ccaaagacat ggccgaaaaa atcagtcaca gattaaaaga
      961 agaaggagcc gtaaacacgt ggatccaaat gttataaccg taacatccta tgctaacatt
     1021 gctattatca aatattgggg aaaagagaat caagctaaga tgattccttc gacctctagc
     1081 atttctttga ctttggaaaa catgttcacc acaaccagcg tttccttctt accagatact
     1141 gcaaccagtg atcagtttta cattaacggt gtcttgcaaa atgacgaaga acataccaaa
     1201 atttctacta tcattgacca atttcgccaa cctggtcagg cttttgtaaa gatggaaact
     1261 caaaataata tgccaacagc tgcaggttta tcatcaagtt ccagtggttt atcagccttg
     1321 gttaaagcct gtgatcaatt atttgacact cagctagatc agaaagcttt agctcaaaag
     1381 gctaagttcg cctcaggatc atcttctcgt tctttttttg gcccagttgc tgcttgggac
     1441 aaagatagtg gtgctattta caaggttgag actgacttga aaatggccat gattatgctg
     1501 gtcttaaatg ctgcgaaaaa gccaatttct agccgagagg gcatgaagtt atgccgcgat
     1561 acctcaacta tatttgatga atgggtagaa caatcggcaa tcgattacca acatatgctt
     1621 acctatctca aaactaataa ttttgagaaa gttggtcagt taacagaagc taatgccttg
     1681 gccatgcatg ccacgacaaa gacagccaat cctccctttt cttacctaac aaaagagtct
     1741 taccaggcta tggaggctgt gaaagaactg cgtcaagaag gttttgcttg ttattttacc
     1801 atggacgcag gtccaaatgt gaaggtccta tgtttagaaa aagacttggc tcaactagca
     1861 gaacgacttg gcaagaacta ccgtattatc gtttcaaaaa caaaggattt accagatgtc
     1921 taattattgt gtgcaaacag gtgggaaact ataccttaca ggcgaatatg ctatcttaac
     1981 accaggacaa aaagccttaa ttcactttat tccactgatg atgacagcag aaattagccc
     2041 agcagcccat attcaattag cttcagatat gttttcccat aaagcgggca tgacacccga
     2101 tgcctcttat gcactgattc aagcaacggt taaaaccttt gctgattatc taggacagtc
     2161 aattgaccaa ctggagccat tttccctaat tataacggga aaaatggagc gcgatggcaa
     2221 aaaatttggc attggttcaa gtggtagtgt caccctctta accttaaagg ccttatcggc
     2281 ctattatcag atcactttaa ccccagagtt actctttaaa ctagcggctt ataccttgct
     2341 taagcaagga gataatgggt ctatggggga tattgcctgt atcgcttacc agactttagt
     2401 cgcctatacc tcctttgacc gagaacaggt cagtaactgg ctgcagacca tgcccttaaa
     2461 aaaacttctc gtcaaagatt ggggttacca tatccaagtc attcaaccag ccctgccttg
     2521 tgactttttg gttggctgga ctaaaatacc tgctatttca aggcagatga ttcaacaagt
     2581 gacagcaagc attaccccag ctttcttaag aacaagttac cagctaacgc aatcagctat
     2641 ggtagctttg caagaaggtc ataaggaaga actcaagaaa agtttagcag gagcaagtca
     2701 tctcctaaaa gagcttcatc cagctatcta ccatcctaag ctagtaacct tggtagctgc
     2761 ttgtcagaag caagatgctg ttgctaaatc ttcaggttct ggtggtggag attgtggcat
     2821 cgcgcttgcc tttaatcaga atgccagaga tacccttatt tccaaatggc aagaagctga
     2881 tatcgcatta ctttatcaag aaaggtgggg agagaatgac caaccgtaaa gatgatcaca
     2941 tcaaatatgc cctcaagtac caatcgcctt ataatgcttt tgatgacata gaactcatac
     3001 atcattcctt acctagctat gatttgtttg atattgatct cagtactcat tttgccgggc
     3061 aagacttcga ctttcccttt tacatcaatg ccatgacagg aggaagtcaa aaaggcaaag
     3121 ctgtcaatga aaaattggcc aaagtagcag cagcaacagg gattgtcatg gtgacagggt
     3181 cttatagcgc tgctttaaaa aatcctaacg acgattccta tcgtttacat gaggtggcag
     3241 ataacttgaa actagccacg aatattggtc tagataaacc tgtggcgcta ggacaacaaa
     3301 cggttcaaga aatgcagccc ctctttttac aggttcatgt gaatgtgatg caagagttgc
     3361 tgatgccaga gggtgagcgc gtctttcata cctggaaaaa acacctcgct gaatacgcta
     3421 gtcaaatacc agttcctgtc attctcaaag aagttggttt tggcatggat gtcaatagta
     3481 tcaagctagc acatgaccta ggcattcaaa cctttgatat ttcaggaaga ggagggacct
     3541 catttgccta tattgaaaat caaagaggag gagaccgctc ttacttaaac gattggggac
     3601 aaaccaccgt tcagtgcttg ctaaatgcac aaggactgat ggaccaagtg gaaatcttag
     3661 cttcgggtgg tgtcagacac cccttggaca tgattaaatg tttcgtccta ggagcacgtg
     3721 cagtgggact ctcacgcacc gttttagaat tggtcgaaaa atacccaacc gagcgtgtga
     3781 ttgctatcgt taacggctgg aaagaagaat taaaaatcat tatgtgtgct cttgactgta
     3841 aaactattaa agaattaaag ggagtcgact acttactata tggacgcttg cagcaggtca
     3901 attaggcttc atcacctcta caatagtgcc acctactaca aagatgatag agctttttta
     3961 gaacataata taaaatattt ataaatacct catcaaactc agaatagagt agatgagtaa
     4021 atagagtatg ttatggagac tatttctaag acttgtatgt atagaaacaa agattaaaca
     4081 cccatgtaaa ccaattgttt acatgggtgt ttgccttata ttagttgttt aaatctaaga
     4141 ctgtcttagc tgggataagt aaaaatgtgc tttttctaga tttattggtt tatcagctag
     4201 taaagcatta actaaaggag caatttcgtc ttgggttgcc cccgccaaaa gagctaatga
     4261 tttcgcatgt agtttcatgt gaccagcttg gatgccagat gaggtcagag cttttagtgc
     4321 agcaaagttt tgagctaacc ccacagatgc aatcaattgg gctaatgttt tggcatcagg
     4381 ttgattaaga agatcatgtg cgatagaaac agtagggtta agcccgatag atcccccctt
     4441 actagcaata ggcataggga gggtcatttg gccaagcaga acttgtttat cttggtcaaa
     4501 ctgccactga ctaagtcctt gatagctacc atttcttgag gcataagcat gggcccctgc
     4561 ttcaatagca cgccagtcat ttcctgtggc tattaccact gcatcaatac cattaaaaat
     4621 acctttatta tgagtagtag cccggtaagg atctacttga gctagtcggc tggctagctc
     4681 tattttttga gctaactgta gggattttgt tttatcgcga tctaaaaggc gcacgggaat
     4741 ctcacaacta gtagtaacaa gcgactctgt tgcgtaatta gataaaatcg ccattagaca
     4801 atgcccctta gacagtcttg ttaaatcagg aacaagagct tccatcatag tattgaccat
     4861 atttgctccc atagcttctt gggtatcaac agtcagatag aaaatcaaaa actctccttt
     4921 ttcttccaaa tgaatggttc tagcgcctcc acctctttta acaatggaag gataagcttt
     4981 atttgccaat gcaattagct tttttgtttt atgaaggatg gcggctttag cgttatctat
     5041 ttggtcgata tcgtaaagaa caatttgacc aatcatttgt cggtttaggg tttgagcttt
     5101 aaaaccacct gagcgtttga ttagttttgc tgcgaaagat gctgcagcaa caacagaagg
     5161 ttcttccgtg acaaaaggca tctgataagt tgaaccgttg acaagaaaat caggagctat
     5221 gctaaagggc aaagccaatc gtcctaagac attttcagtc atttgattag ctgtttggat
     5281 aggtaaaaga acgtctgttt tgagttgatt taagttttca gcattaagta gtttaaattt
     5341 ttcgataagt tggaggcgtt cttcgaatgt tttctttgaa aaaccgctcc agttaagatt
     5401 agtttttgtc attggtatga tagatccttc gatgctcctt gatggctgtt agagcaaatt
     5461 ttccagttaa gtaaatgtca aaattggcat taccattatc atctaattgg acttgttcgt
     5521 agaaaaggtc ttcgtattta gaaacggaaa gacgtgttcg ttgatccagt aaagcttgtc
     5581 gattagtcat taacatttta tcgtacccag caactaactg accggaataa aattcactta
     5641 cggcaccgga accatagcta aaaaaaccaa ttttatctcc agattgtaat actttactat
     5701 tttcaagtaa agataacaat cctagataaa gtgagccagt ataaatattt ccaatttgtt
     5761 tgctataagt aatagaagct tgaaaggctt ctattagttt ttccctgtgt tcaggaggta
     5821 ctgtgttatc cataatgtta tttagacctt ttagggctaa cttgggaaat ggaatatgga
     5881 aacaaactgc agcaaaatca gataactgaa ggttttctct tttctgataa gcttgccacg
     5941 tggtttctaa gcaattgaga tattgcttgg tagagtaaat accatcaaca taaggtgtga
     6001 aactatagtt aggcctccaa aagtccataa tatccctagt ttgagccaca ttatctttat
     6061 ttagagcaag aatacgaggg ttagcagtta ccaaaagagc aatactacca gagccttgag
     6121 ttgattcgcc aggagatcct acaccgtatc tagcaatatc actagcaata acaaggacac
     6181 gagaatctgg cttagaagcc acatgcagtt tagcatagtc tagagcagca gttgcgctat
     6241 agcaggcttg ttttacttca aaggaacgtg caaaaggctg gataccaact aagtgatgta
     6301 catagatagc tgatgccttt gactgatcag tactcgattc agttgccaaa ataaccatat
     6361 caatcttagc tcgatcttcg tcagttaaga tttgatctgc tgcagaagca gctaaagtaa
     6421 taatgtcttc agtgattggt gccacactaa aagattcaat gagtagccct tgactaaatt
     6481 ttgctggatc cacttggcgt gcaagcgcta aatcttccaa tttcaagaca tattgactgg
     6541 ttgcaaaacc aatcttatca attccaattg tcatatttgt ccttctttta gttattttta
     6601 tagtcttacc cattctatca cattttactg caaaattaga ctgataaagt tatttgtttt
     6661 atcctttaat agttaaaatg ttcatgacca catgaagttt ttcgaatgtt tatttattct
     6721 ggtatttttt ggtaaaatta gttagaatag tatgaagtat gcttacagaa aggttattag
     6781 agatgacaaa agctgaccag atttttaaaa ctaatattca aaaaattata aatgaaggat
     6841 cattgagtga gcaagcacgt cctaaatata aagatggtcg aacagctcat tctaagtata
     6901 ttactggggc gtttgctgaa tatgatttag ctaaaggaga gtttcccatc acaactttac
     6961 gacctattcc aattaaatct gctataaagg aattattttg gatatatcaa gatcagtcta
     7021 acagtttaga tgtgctagaa gctaaatata atgttcatta ttggaatgaa tgggaagttg
     7081 accagacacg tactattggg caacgttatg gtgctgtagt caaaaaacat gatatcatct
     7141 caaaaatact aaagcaatta gcagaaaatc cttggaatcg tcgtaatgtc atttctctct
     7201 gggactatga agcatttgag gagacaaaag ggttgttgcc atgtgccttt caaatcatgt
     7261 ttgatgttag acgtgtaggg gaagatcttt atttagatgc tagtttgacg caacgttcta
     7321 atgacatatt agttgctcat cacatcaatg ccatgcaata cgttgccttg cagatgatga
     7381 ttgctaaaca ttttggatgg aaaataggta agttctttta ttttgttaac aatttacata
     7441 tttatgacaa ccaatttgat caggctcaag aattactaaa acgacagcca gttgctagtc
     7501 agcctaagct tgttttaaat gttccagata ggactaattt ctttgatatt aaaccagatg
     7561 attttgaatt acaaaattat gatccagtga agcctcagtt gcactttgac cttgctattt
     7621 aaactttatt tagatttttt gtgagcattt tgttcataaa ttt
//
LOCUS       DAUGSW010000050         7547 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUGSW010000050 DAUGSW010000000
VERSION     DAUGSW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7547
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.050"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..309)
                     /gene="speG"
                     /locus_tag="VIB18_001458"
     CDS             complement(<1..309)
                     /gene="speG"
                     /locus_tag="VIB18_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEQ8766458.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     P"
     gene            complement(411..509)
                     /gene="ffs"
                     /locus_tag="VIB18_001459"
     ncRNA           complement(411..509)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VIB18_001459"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            709..1941
                     /locus_tag="VIB18_001460"
     CDS             709..1941
                     /locus_tag="VIB18_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEQ8766459.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(2555..3070)
                     /locus_tag="VIB18_001461"
     CDS             complement(2555..3070)
                     /locus_tag="VIB18_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEQ8766460.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(3070..3849)
                     /locus_tag="VIB18_001462"
     CDS             complement(3070..3849)
                     /locus_tag="VIB18_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8766461.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRNEFA
                     KLSIPDVSEGRAFDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PDGINSKNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(3989..4528)
                     /locus_tag="VIB18_001463"
     CDS             complement(3989..4528)
                     /locus_tag="VIB18_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEQ8766462.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(4532..4843)
                     /locus_tag="VIB18_001464"
     CDS             complement(4532..4843)
                     /locus_tag="VIB18_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766463.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(5060..6202)
                     /gene="tgt"
                     /locus_tag="VIB18_001465"
     CDS             complement(5060..6202)
                     /gene="tgt"
                     /locus_tag="VIB18_001465"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEQ8766464.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            6421..7284
                     /locus_tag="VIB18_001466"
     CDS             6421..7284
                     /locus_tag="VIB18_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEQ8766465.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGGSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
BASE COUNT         2358 a         1550 c         1351 g         2288 t
ORIGIN      
        1 tggggaaaaa ttataaggga gaccaaaaac atcgacctta tcccctttta taaactgatc
       61 agtaatgcct aaagatacaa tagaatcaac ataaagaata cattccgatc ttttttgttt
      121 agtattaata tgtatgctat ttgtagtaac aaatgcaatt tctacatttt cataatcgca
      181 tggggtaata ttataggcaa accttaaact tctttttaaa tcttttaaat tttcatctgc
      241 ataagctaat tgacttccat agctaaaaac acatgataat atgataattg tcaaaatgtt
      301 tgttttcatt taaaactttt tatgtcctgt tttatacctc ttaacctaaa taaaaatatc
      361 aatcggtttc aacaactgat gacactatag aaggaggaga tcactttagt aaagtcaaca
      421 aaaaaagagc acacacccga aaatcgctta gggctgctgg attcctcccc tgacccactt
      481 cacgcacaag tgttgctccg cctattatta tatcatatta cggacagttt gcaagttttc
      541 caactaagta aaatcacttt caagtgagca tagcttcatt ttgggacaag atggactgaa
      601 tacctagaaa aatcatgacc ctttccaaac acgattttgc tttttgaaaa tctttccctc
      661 tccccattcc agctattctc tatgttataa taagattatt agattagaat gggagttatg
      721 atgaaacaaa agattaaaat cttaacagta attggcctta tgacagttgg tatgtctgcg
      781 tgtcacaaca ctagcaaacc ttctaatacc gattctgttt tttctttaac cggaaaaaag
      841 cgccaacaaa tcgtcaaaca agtaagacaa cggtattatt tccaacaatt atccaaaacc
      901 gaacaagaaa attacctcac tttatacgat agtctagcac aatttcgtga aatcatcagt
      961 ttgacgccgg cttctaaaaa aagcttaatt aaaacaattg acgcctttgt gatggataat
     1021 cccgaatttt actggattac atctgccgat tatcgatttg agttttctga tcaaacggtc
     1081 tttgtcacct ttcctatccc agaagatgcc aagaacgttt atcaagactt gcaagcaatc
     1141 ggtaatgata tcgtcgcaaa cacgccatca aaggatcgct atgagcaggt caaatatttt
     1201 tatgaggtca tcattcgaga cacagactac aataaaaaag cctttgaagc ctatcaatca
     1261 ggcagtcaag cccaggtcgc ttctaatcaa gacattaaaa gtgtttttat tgatcattta
     1321 tctgtttgta atggctatgc ccaagccttt cagtttcttt gtcaaaaagc tggcattcca
     1381 gtcgcctata tccgtggaac tggtacatct cagcaacctc agcaatcttt tgcacatgca
     1441 tggaatgctg ttcaaattaa taacacttat tatggcgttg atgtcacttg gggtgaccct
     1501 gtttttgata accatctctc acatcaaaag caaggaacta tcaattacag ttttctatgc
     1561 ctgccagatt atctaatggc cttatcacat cagccaagca aagacattgc ttttaatact
     1621 aaagaacgtt ttgaaaatgt ttggactata ccttcttgta cagatgattc tttgctttat
     1681 tctaaacgtc atcaaagcta tatctcaacg tttgacagtg acgccatcct tgcaagcctt
     1741 gaaaatcagt tgttaaatag acaagagcca ctgtctctac aatttgctca tcaagatgat
     1801 tatcaacaga tggtaactga tttaacgacg aatcaaacag gttatcataa ccttttcaat
     1861 cagtattgga ataattatac gggctttacc tatggactct taccagagac tcttagtatt
     1921 tcatttgcta gtaggaacta ggtttagaca catgaaacac aaagttaaga tgattatctt
     1981 tgtcaaacat tacaagaaat tgatatacta acacaattga aggcgattat tattctaacc
     2041 gtcttcaata gatataacct tttcagattg agcacatcta atgcttgtaa cattagcaac
     2101 agtgatgagc tcttttttaa tgctttagca aaatatatca gctaagacaa aagattaaat
     2161 aactcaagct atgcctataa gtcacttgtt tttaatccct gtgtcagtgt caatctacgc
     2221 cacagataac tgacagctct gagccctaga agtctgaact tgataagttt actaaaaaca
     2281 aaaataaggt gagccattac tatctgtttt tagatagtaa atctttttaa gaatgactaa
     2341 ctcatctagt catcacgtgt tttatttttc gattgttttc atctcgattg ggtctgaaaa
     2401 agagcgcttc tagtacttgg aaacgccctt ttgtatattc tatcttcgta tgttgaatct
     2461 aacaaccatt ggaaaaatgg tctaacgttt cactcagtat tttgacaggc tacccttcac
     2521 caaaaatgca tgtgataaca aactccttaa aactctagtc aaagggatct gactgttcct
     2581 tgatcaaatg cttagctatt tttttgcgct ctcgcccttg gcggaaaaag gtttgcatga
     2641 tgttagcaca gtctgctgct agcaggcctc gttcaacttg cacgcggtgg tttaagcgct
     2701 catctgtcaa aatctggtaa aggctgtctg ctccaccaaa tttttgattg ctggctccat
     2761 aaataacatg cggaatcctt gctagcccaa tggcaccact acacatcaca caaggctcga
     2821 tggtcacaaa gagtgtggtg tccaataatc gccagtttcc ttcatgagca ttagcctcgt
     2881 taatggccat catttcagcg tgcataatgg cttggttact ctcttcacgc gcattgtgcc
     2941 cacgaccaat aatctcacca tccttgacaa tgacacagcc aatggggatt tcagctttct
     3001 gtaaggattt ttcggcttct tttaaagcct cttgcatgaa ataagtttgc tcttctaaac
     3061 tatatggcat caagaaagac tccccaagtt ccaagatttg tgtggtaagg caaggtcaac
     3121 aggaatatta cctgcatagg cctgtgtttc ttgcctcaac acttctaaat ggtttttgga
     3181 attaatacca tctggaggaa ccggtggcat gtgggtcaag acaagcttct taacacctgc
     3241 ctggctagcc attagtcctg cttccttact ggtcaaatgg gccatatgat tttcattgcc
     3301 ttcgtataag taaacatccg ctaagaaaag gtctgcttct tttgcgaagt ctgccaatcc
     3361 ttcaaaataa ccactgtctc cagtaaagac aagtacctga ccagtcgctc tttctacaat
     3421 tcgaaaggca taacacacaa ctggatgaac tgttttaaga aaggtaatat caaaaggacc
     3481 aatctgttca actccagtaa catcaaaggc tctaccttct gaaacatcag gaatgcttaa
     3541 cttagcaaat tcgtttcggt cctcatcatg cccataaatg ggcaatactt taggctgcca
     3601 caggtgttta ggataaagtt gaaaataatg gcgcagcacg cctaaatcgg ccacgtggtc
     3661 tggatggtaa tggctaataa tcactgcatc caaatcgaga ggactgattt ctttttccag
     3721 ctcattgagc gctcgactac cagcatccat caataactga aagccgtcat gtcctgtgac
     3781 caaataagag gttgtgcctg catcttgata gggataggct ccccaagacc ctaaggtggt
     3841 taatttcatc tcaaaccctt ctttcttgct ttaactctta ttataacaaa aattagtgtc
     3901 aaagaggatt gagacccacc aaaaacaggt cctagcagat aaatctgcca agacctgttc
     3961 aacacaactt aactatttga tgattagatt actgttttgt attcaaaaaa ctatctttgt
     4021 atttaacagc gataatggtc gcaatgattg ctttgatggt atctcctgga ataaagacca
     4081 agtttgacaa aagcgatgtc acaagagaca tgccagtgta ggctgccaac cagatagcac
     4141 ccagaacatc aaccagtaca actcctgaga ttaaaagagc taggaatgct aatggcgtgc
     4201 tttttgagaa ccagttgcgg taaagtaatg aaaagacaat aggcacaaga aggtaggcaa
     4261 taacatagcc agcagatggc cccatcaata ctggaatggt tgttcttgag cctgagaaaa
     4321 caggtaagaa aaggccaatc actaaaaata agaaaacaga taaggttccc tttttaccac
     4381 ccagcatcaa tccagccaac atgacaccta agttttgtaa aacaataggg actgggataa
     4441 agcctagcgg gatagcagga ataaagccta aaataataat caaagtggtc atcatagcca
     4501 ccttaacaag ttctttggtt gtaaacatca gttacgactc ctttaaaaaa tagatatcct
     4561 tgtgcctatg acaggctgga ttaaagggac tttgacaata aggacagcat ccacaaccat
     4621 actcagctag gctcaagagc tttcgacaat gcccacaaat aacaggagat gtttcttgat
     4681 gtcctgttgg cacaaaggca tgatctgtta actggtcatg gcaatggtaa caagcataat
     4741 aagtctgaca aaaagcacat ttgagcccaa caatatcaag cggggtatga taatgtaggc
     4801 accgatactc ttggtcaagg tcaattccaa aacagtccgt catatctcat cctcttgtaa
     4861 tagtttaatc aaaagcttat agtttgtcaa ctctattttt acaaaagggt gactgttttc
     4921 tgaaaaagaa cacgtaaaac aagaacttcc ctttaaagag tgacctatca gttgaaagca
     4981 ataggacatc cgtctataca aaaaaactga aaccaaagac gatagatcgc cctcagttcc
     5041 aggatcatag catttttaat tagaaattac ggtttgattt attataacca taccgttcaa
     5101 gaaaatcttg gcggaattca agtaagttat cgtccataat agcctgacgt acttttttca
     5161 tcaagttaac caagaaataa aggttgtggt agcttgtcaa acgaatacca aaagtttcgt
     5221 ccgcttttag caagtgacga atgtaggcac ggctatagtt ttgacaagtg tagcagtcac
     5281 agtcatgatc aagtggggta aaatcttcag cgaatttggc atttttaacc acaaggcgcc
     5341 cctcgctagt catacaggtc ccattacggg caatacgcgt tggtaagaca cagtcaaaca
     5401 tatcgacacc acgaatcaca ccatcaatca agctatctgg tgctcccact cccatcaggt
     5461 aacgaggttt attttctggt aagaggggag tcgtaaagtc aaggacggca ttcatttctt
     5521 catggctctc cccaacagct aaaccaccaa tagaataacc tgggaaatcc atagccacca
     5581 aatctgccgc agactgacga cgaaggtcct caaatccagc tccttgcaca attccaaata
     5641 atccttggtc atgaggacga cgatgggctt ttaggccacg ttctgcccaa cggctagtac
     5701 gttcaatgga ttttttcacg taatcataag gttggtaaaa ttgcgggcac tcgtcaaaac
     5761 tcatcatgat gtctgagcca aggttattct gaatggaaat ggctttttcg ggtgatagaa
     5821 acatttttga gccattcaag tgatttttga aagtcactcc ttcttcagtg atgtttcgtg
     5881 aatcggctaa agagtaaact tgaaaaccac ccgaatcggt taagattggc tgatcccagt
     5941 tcataaactt gtgcagtcca ccagagcgag caatcaactc atctcctgga cgcaaccaga
     6001 ggtgataagt gtttgataaa ataattcctg atccaattgc ttttaactct tctggagact
     6061 gtgttttaac agtagcctga gttcccactg gcataaacat tggtgtcgga aaggtcccgt
     6121 gaggggtgat aatttcgccc aagcgtgcac cggtgtgctt ttctgttttg ataaggcgat
     6181 acttaatcgg ataatctgtc atgtgctttc ttccttgcta tcaagataaa cagtcttgag
     6241 cttttttgat ctgcctgagt ttccatcata atgaagggct tcaagatgac atgttgttct
     6301 agcgcctatc attttatcaa aaaatccata atttgtcatg ctttcccaaa aaagtatagt
     6361 caaaataatg gttagctgtc tcattttgtt ttatggtata atgaaataaa ggagtctgtt
     6421 atgtcaatta aagcaatcaa aggtcaggct agagacacgt taaaaaatct ctctggcaag
     6481 tatttactat ttttaattcc aacccttctc tttatgtttc atttcggtat tgagattcat
     6541 caaggttacg tcctatctag tggtattgaa gtctcgctag cggctagtta tttcccatta
     6601 ctactaggac ttatccttag ccttttcatt ttatcagcat cctttacgat gattgatgtt
     6661 gttaggcatt ttcgtcagaa agtttctttt gccgaatcaa caacagcctt ctcaaaagaa
     6721 ttctttggga acctgctggt tttagcgatc actaagtggc tattctttct catctggtca
     6781 ctaatttggt tttttggcct ctttattttc ctttccggac tttcagcgtt tttggtcaat
     6841 gctaaatcag gtggctcaac agtcatttca ctgatctttt tactatttgg agcagttttg
     6901 tccttaattg gttttggtat ttatatcaac cgttattacg cttatagtct atcagaatac
     6961 cttctctacg ataaggttaa agaggggact tatctaggag ctatagccgt cattgaaaca
     7021 agtgtagcta tgatgaaagg ttataaatgg aagctttttt tcttacaact tagcttcacc
     7081 ggttggtttc tactgaatat tgttactttt gggttactta atatctatct tttaccatat
     7141 tttacaacag ccaatgtcat tttttatgat caactcaaga aacgtttcaa agacaaagat
     7201 gacccaattg aaggagaaca tttaagcctt catcagctta ataaaaagcc tactcctatg
     7261 atgtatgacg atcaaaaaga ctaaataaat cctccatcca taaaaatagc ccttgaactg
     7321 caccccaaaa gttagacaca aaatctaacg attgaggtgc tattttttta tgaaatttaa
     7381 tcaagaaacg aaagttaaga tttatgagtt acagcaaatg ggagagtcca ttaaatccat
     7441 atcaaaaaag tttgatatgg cagaatccga tctcaaatat atgattcgct tgattgatag
     7501 gtatggggta accatcgttc aaaaatgtaa gaataattat tattctc
//
LOCUS       DAUGSW010000051         7467 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUGSW010000051 DAUGSW010000000
VERSION     DAUGSW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7467
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.051"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(69..278)
                     /locus_tag="VIB18_001467"
     CDS             complement(69..278)
                     /locus_tag="VIB18_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8766466.1"
                     /translation="MRFSYNELWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
     gene            complement(268..1926)
                     /locus_tag="VIB18_001468"
     CDS             complement(268..1926)
                     /locus_tag="VIB18_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEQ8766467.1"
                     /translation="MLIEMWSPVFKKHGEIREPICFHHGLNVIMRMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHSIYFCFQFEKKFYFSRDTANPDIILVCDKSYSP
                     TGETMDLGIFLNRLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYAFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDIEKNQQKIQLRNTKLELDNSLRDKQRRLKLLAISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLATILDSEFSTERESLIAEIDEL
                     ESQLTTLNQELQELGNIPNLSSEYLENYSKLTATINALKEQNEAYLKESGLSKEKSEA
                     DADLKRSTEDILLDLEVKINSKMREVNNILYPDIRKAPQINLNAHNSYSFYTPDDDGT
                     GTKFKGMIVFDLVMLYLTNLPALAHDSLLLSNVSYQATEALLKLYDQSRSLNKQVFLA
                     FDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            complement(1917..2147)
                     /locus_tag="VIB18_001469"
     CDS             complement(1917..2147)
                     /locus_tag="VIB18_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766468.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEGEVKLCL"
     gene            complement(2147..3040)
                     /locus_tag="VIB18_001470"
     CDS             complement(2147..3040)
                     /locus_tag="VIB18_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766469.1"
                     /translation="MTTMVDFPFHHEFIESLGRWTHILITLPKRHHGQVDTAIPRYLL
                     VTIREKTGIVKLTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKIVTALKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTLYQLVKNQVI
                     DNYLTIQKIIVNLDKQGKIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHKATL
                     QDIYFCQTIVSYFIQKCEVLE"
     gene            2945..3232
                     /locus_tag="VIB18_001471"
     CDS             2945..3232
                     /locus_tag="VIB18_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766470.1"
                     /translation="MVPFGQGYKDMSPPSKGLYKLMMEGKIYHGGHPVVKWMGQNVVM
                     RQAPAGNIKPDKEKSVEKIDGIVGLILGLDRCICRQGDEASVYDERGILSF"
     gene            3287..3589
                     /locus_tag="VIB18_001472"
     CDS             3287..3589
                     /locus_tag="VIB18_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEQ8766471.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLSQLKENA"
     gene            3589..3894
                     /locus_tag="VIB18_001473"
     CDS             3589..3894
                     /locus_tag="VIB18_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8766472.1"
                     /translation="MKEYQVTMSDDAKADLLNIYHYVRDELCAPQAADNLLERLSQGM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            3913..4133
                     /locus_tag="VIB18_001474"
                     /pseudo
     CDS             3913..4133
                     /locus_tag="VIB18_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4238..4690
                     /locus_tag="VIB18_001475"
     CDS             4238..4690
                     /locus_tag="VIB18_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8766473.1"
                     /translation="MGLLDLIGRKRARDKPQNSYEGQDFSYLFGRTTSGENVDEFKTM
                     QTTAVYACVRILAEAVASLPIHIYERTENGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TIMSHLLIWGNAYVQIIRDKSGMVSLLLKQKASVLIRKLLLIIWQRMS"
     gene            4756..5070
                     /locus_tag="VIB18_001476"
     CDS             4756..5070
                     /locus_tag="VIB18_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766474.1"
                     /translation="MTRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNGNL
                     SIDTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVR
                     ID"
     gene            5487..5825
                     /locus_tag="VIB18_001477"
     CDS             5487..5825
                     /locus_tag="VIB18_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEQ8766475.1"
                     /translation="MKPPFTVTNTMLNKVVEISKIIGNLELQVQKDLKLRKENRIQSI
                     HSSLAIEQNSLTVEQITAIIDGKRVLGNPREIREVKNAYEAYEEILTLTPYDESHFLK
                     MKEFQQYIYR"
     gene            5849..6720
                     /locus_tag="VIB18_001478"
                     /pseudo
     CDS             5849..6720
                     /locus_tag="VIB18_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528389.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine ligase"
     gene            6734..>7467
                     /locus_tag="VIB18_001479"
     CDS             6734..>7467
                     /locus_tag="VIB18_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEQ8766476.1"
                     /translation="MKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFV
                     ETIETSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSF
                     RFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNF
                     SELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIY
                     TPLGITKKIVDEKLFMDEIGHIFPSN"
BASE COUNT         2354 a         1147 c         1545 g         2421 t
ORIGIN      
        1 tttttcaaag taaaggcact aagttgatct gatttacaca tcttatcaac tcagtgcttt
       61 ttttatttct agatattatt atctacaatt tctactatat cttcaatctt acaatcaagt
      121 gcaatacaaa tttccaataa aatatcagta gtgatatttt ccccttttcc caattttgcg
      181 atcgtggaag aactaatccc agcttcttgc ctgagctttg ttttggtcca acctttatca
      241 ataagaagtt tccataattc attgtaacta aatctcatct gagttttctc ctttgttcca
      301 tgaaataccg tagagttcat ttccgttact agagagtctc aataccgtat tttctgacaa
      361 gagttgatta gcatctggag aataagagct ggctttatcg aaggctaaaa agacttgttt
      421 gttcaatgac cttgactggt catatagctt caaaagtgct tcagtcgctt ggtagctaac
      481 attactcaag agtaatgaat cgtgtgcgag tgctggcaga ttagtaaggt agagcattac
      541 taagtcgaat acaatcatcc ctttaaactt agttcctgta ccatcatcat ctggtgtata
      601 gaaggagtag ctattgtgag cattgaggtt aatttgagga gctttgcgaa tatctggata
      661 tagaatgtta ttgacttcac gcatcttact gttgattttt acttctagat ctagaaggat
      721 atcttctgta ctgcgtttca agtcagcgtc cgcttctgat ttttctttgg atagaccaga
      781 ctcctttaag taggcctcgt tttgttcttt tagtgcattg attgtagctg ttagtttaga
      841 gtagttttct aagtactcac ttgaaagatt tgggatgttt cctagttctt gaagttcttg
      901 gtttagagtt gttaattgac tctctaattc gtcgatctca gctattaggg attcacgttc
      961 agttgagaat tcggaatcta aaatagttgc caattttttg tggtaagctt caacttcata
     1021 taattttttg agattagtat ctgggaagta ttgttgaagt tctgttaagt cagattcagt
     1081 aggatataag ccaaattcga tactgatggc caatagctta aggcgtcttt gcttatctcg
     1141 aagactatta tctagctcca gcttagtatt tctaagctgg attttttgtt gatttttctc
     1201 aatatcatca gagtcaattt tatcttgatg agtatcttgg agatgtgcta aatcatattc
     1261 caatcttttt atttctgaga cattcgcttc aaattgcttt ttaccgccaa ccaggttgga
     1321 gatgaaggca tactttcgag cattacgaaa agttgttaac tggtcgctct tatctttcag
     1381 acgttctttg tatcgtgcaa tgttatcata caaattaaac agttggatga gagtagtaat
     1441 agattcagaa gatttttggc tcgaataaac ttgtaagggg aaatcggtat tttgattact
     1501 ttttcctgca atcctaaaga agccactcat agctaatcgg aatgatagct ctggagaatc
     1561 taaatgatat cgtttcttaa gtctgttaag aaaaattcct aggtccattg tttcaccggt
     1621 tggagagtag ctcttgtcac acactagaat gatatctggg ttggccgtat ctcttgaaaa
     1681 ataaaacttt ttctcaaatt gaaagcagaa gtagatagaa tgatcaccta attttttaac
     1741 cgcaattgat tttagatagc tattacctcc aaagatgaaa tcaatggcta atagtgagga
     1801 ggatttgccg atagagttat cagctaaatc catcctcata atcacgttta acccatggtg
     1861 gaagcagatt ggttcccgaa tttctccgtg tttcttaaat actggagacc acatttctat
     1921 aagcataatt ttacttctcc ttctccttca ttagacattt caatagcgtt caatgcatac
     1981 aagcaatcca ttatagatag gaaatctgta ggatcatcca actcttctga gatagcgtga
     2041 aagatatctt tgacgtttga gtttccactt ttgatttcat ttagcactct aggcaaataa
     2101 gcaagggtgc ttttttgata ggagtaaagt ttatttggta attgcattat tcaagtacct
     2161 cgcatttttg gataaagtaa gagacaatcg tctgacagaa gtagatgtcc tgtagtgtag
     2221 ctttatggag tttttctgaa atagtattga aaatagccag attattatgc ttggctgctt
     2281 ttaacttttt atacatcgat cgcgtttgat attggatttc ctcgtaatca atttttcctt
     2341 gtttgtccaa atttacgatg attttttgaa tggttaagta gttatcaata acttggtttt
     2401 taaccaattg ataaagcgta cgattgttct caggtgatat cttatcagtc aattgcttcg
     2461 agtcatagga gatatcatat tcatcacatt ttagtttatt gagactagtc aaaactgaaa
     2521 caattccact gtctaacttc atatcagaaa tcgcttgttg gctgttatgt gcagagacta
     2581 gaatcttttt aacatttttt agagctgtta caattttttt gcgactatct gcttgatagg
     2641 ttaaaaaaca atctgggcag agggctatca gattcagtgg ttcagcgtcc ttatcttttt
     2701 caatggctga aacctcgtaa ttttctgctg ctaagttgcc actggttaga atgagtggtc
     2761 tatcacagcc tgggcatgca caacagttat tagattctgt taacaagaac tgcccgtatt
     2821 gttttttgag ttgattcgac tgggtagtga acgctgtatt ttgcacagtg gttaacttta
     2881 caatccctgt cttctctctg atggttacca gaagatacct tggaattgcg gtgtcgactt
     2941 gaccatggtg ccttttgggc agggttataa ggatatgagt ccaccgtcca agggactcta
     3001 taaactcatg atggaaggga aaatctacca tggtggtcat ccagtcgtta aatggatggg
     3061 acaaaacgtg gtgatgcgac aagctcctgc aggcaacatc aagccagata aggaaaaatc
     3121 tgttgagaag attgacggta ttgtaggtct tatcctgggg cttgaccgtt gcatttgccg
     3181 ccaaggtgat gaagctagcg tctatgatga gcgagggata ttgagttttt agttgagtca
     3241 actccaaaaa tgtgatacaa tgtcgttaca aaaaaggagg ataaccatgg ctaaaacggg
     3301 aactttgaat ttacgagttg atgattcagt aaaaagtgcg gcagatgata ttttgaaacg
     3361 cttaggtatt cctatgtcaa ctgcgattga tatgtttttg aatcagatta ttttgactgg
     3421 gggtatccca tttgatgttt ctctacctga agcgcctcaa cgagttaatg ttgattacat
     3481 gagtcaggag aagttttatg ataagcttat caccagcttt gaagatgcga aaactggcaa
     3541 ccgtcaggat gtcagagaat ttctatctca attgaaggaa aatgcttaat gaaagaatat
     3601 caggtcacca tgtcggatga tgctaaagca gatttgctga acatctatca ctatgttcgt
     3661 gatgaactct gtgcaccaca ggcagcggat aatcttcttg agaggttatc ccaaggaatg
     3721 ttatcactat ccatttttcc tgaacgttgt gccatcattg aggatctgat tggaaaaggc
     3781 tataccttca gacagctgat tgtcaaaaaa tatcgcattg tatatcatgt tctggaagat
     3841 gaagttataa ttgttgcggt cgtctatgga tcacgtcata tgaataattg gtaaagtaag
     3901 ggagagtgat gtatggaact cgtaaagacg atacaaattg gtgatgacat ctatcctccg
     3961 atacctgacc catttggcat tcaagagaat caggagttta acctttataa atcaactgat
     4021 ggaactttgg tgatgagcag atgacaacag ttgttgaaca agcaaggtta gatgagattg
     4081 cgacttcagt attatcacga catcttgacg catttaagga attgacagaa tgagaatact
     4141 aggttttgta agaaagactg ttgattactt tgaaagaaat ataccgaaag cacttcaaag
     4201 ggggtgcttt ttttgtaccc caaaataagg agggcttatg ggactacttg atttaattgg
     4261 aagaaaaagg gctagagata agccccaaaa cagttatgaa ggtcaggact tttcctacct
     4321 ctttggtcgc acgactagtg gcgagaatgt ggatgagttt aagactatgc agacgacggc
     4381 agtctatgcc tgtgtgcgta ttcttgctga agcggtggcg tcacttccta ttcacatcta
     4441 tgaacggaca gaaaatggga aggagaaaaa gctggaccac ccactgtact ttcttcttca
     4501 tgatgaaccc aatccagaga tgtcctcctt tatctttcga gagacaatca tgagccatct
     4561 tttgatatgg ggaaatgcct atgtacagat tatacgagat aaaagtggta tggtatcgct
     4621 actgctaaag cagaaggcga gcgttttgat aagaaagctg ctcttgatta tctggcaacg
     4681 gatgtcttag aagcacgagt tgcagcactt caaaaagcta agattgatga gttgaccgtc
     4741 tctagttcag catggatgac aaggcttatc tcccaacaga ttctatcaga gtatgtgaag
     4801 agcctagaag ttgaagctga taaggtcgtt attccaggac agaatactcc agtctttagt
     4861 tgggataggg atgggaatgg gaatctttcc attgacacac cgctcctaaa ggtgagaggg
     4921 gaaagtctag cgacacaagc tgaccttaca accatctctt taactcctgg tccaaaggga
     4981 gaactctggc agacaagtgt tgaaaggttg gatataaaag tagacaagca catcagccta
     5041 accttcaaaa atggcgtacg gattgattga taaaaggcaa gggcgtatca attcggcacg
     5101 tcctttttta gtttatctgt ggtataatga aagaagttat attgggagtt gagatagacg
     5161 attcatttga attttgcact ccctaaaaag ggtaaaggtt agattgtatg ataaaactaa
     5221 tagcaacaga aataggaata aagtggataa tacaataaaa gttctaaata gcttgaaaca
     5281 aagggactag gagtttgagt gggagtttta atactctagg gtaattttat gtagagtatt
     5341 tgaaaataat aacgttaaaa agttagtaat cgttaaagaa tttaaaataa attgtaatag
     5401 tttatcgctt gttttatcgc ttgaagaacg agcgataaat ttatttttat ggtataaata
     5461 agaaaaaaga ttgtaaggag aaaatgatga aaccaccttt tacagttacg aataccatgt
     5521 taaataaggt agtagagatt tctaaaatta ttggtaattt agaattacaa gtacagaaag
     5581 atttaaaatt aagaaaagaa aatcgtattc agtctattca ctcatcactc gctattgaac
     5641 aaaattcttt aacagtagaa caaataacag ccattattga tgggaaaaga gtgttaggga
     5701 acccccgtga gataagagaa gtaaaaaacg cttatgaagc ttatgaagaa attttaacgc
     5761 taactcccta tgatgaatca cattttttaa aaatgaagga atttcaacag tacatttacc
     5821 ggtaacaaca tcgtcaatca caagtcctat ggggttgggg agtgattcgc tacctgtaaa
     5881 aatttcctta tttgatgttg atacctatct tgcagattcg atgcagtttc acttagagta
     5941 tatacttaga ctttttccaa agtcaggagt tcatcactta atgcctactt ttagaggaga
     6001 agcagtagat catcgacatt tatcgcaatt ttatcattta gaggagaagc agtagatcat
     6061 cgacatttat cgcaatttta tcatagtgag tgtgagatag agggagattt acacgatgtg
     6121 atgaatttag tggatagata tattaagttt ctggttagtg aaattcttag agagtgtcga
     6181 gatagtattt ttgctataac aaaagatgta agtcatttgg aaagttttat tgatcgaaag
     6241 ataccaatta ttacgtttga agaggcttgt actatattgg aaaatgaaat agattcattg
     6301 gaatataatg atgaacatca tttttatgtg ttaacagatg ttggggaaaa gaaattaatg
     6361 gaacattttg agggagtagt ttgggtaaaa aattatccct gtaaaagtgt ccctttttat
     6421 caaaggttct caacagatca tctatttgcc tataatgcag atttgttgtt aggaataggc
     6481 gaaactgtag gttgtggaga aagatgcgaa acatatgaag aagttgtaga aaatatgaat
     6541 tatttacaag tagatgcttc tgaatatagt tggtatttag aaatgaaaaa aacaagacct
     6601 atgaaatctt caggatttgg tttaggagta gagcgtttaa tagcgtggat attgaagtgc
     6661 gatgatgttc gaaaagttca attaatcagt agagaaaatg ggattgatta tttaccataa
     6721 aggaggaaga aaaatgaaaa agaatatttt aattgtaggt ggaggtccag agataactat
     6781 atgttatgat ttaattaaca atagtacgga gtataatttc ttttcagtat cagaaattcc
     6841 tacgatgtat ccagagttgt ttgtagaaac aattgaaacc agctttagaa attttggaaa
     6901 gacgattgaa caaattaaag agctcaaata ttctattgat gctgttgctt gttgggatga
     6961 agctttaacg catatagctg atgatatttc aaaagaatta ggattgaacc ctatttcatc
     7021 gctagattct caatcattca ggtttaaaga tcgaatgaga atggtatgtg aagctggtgg
     7081 actaaaaatg cccaaatata aaattatcaa tcaattttca gatacaaata aaataatcaa
     7141 ttggaaatat ccattaatag tgaaaccaac ctctttttta gcaagtatag gagtgaaaaa
     7201 agtttataat ttttcagaat tacaacaagc agtttctcaa atgcttaatg taaaatttcc
     7261 ggtttacata gcttcagggg tatatgaatt gggggaatta tataatttag aacctagagt
     7321 tttggtggaa gagtttattg atggagaaga atatagctta gagagcgtgg taagaaatgg
     7381 aatctataca cctctaggga taactaaaaa aatagtggat gaaaaattat ttatggatga
     7441 aataggccat attttccctt caaattt
//
LOCUS       DAUGSW010000052         7229 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUGSW010000052 DAUGSW010000000
VERSION     DAUGSW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7229
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.052"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            322..561
                     /locus_tag="VIB18_001480"
     CDS             322..561
                     /locus_tag="VIB18_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8766477.1"
                     /translation="MRKQEQDHHKQDVNQMKPEEMTKLERLQEENEYLRTEVAYLKKT
                     RELRLKEATLQRRRQKTIIKNGQRRALIRFSFKNC"
     gene            579..671
                     /locus_tag="VIB18_001481"
     CDS             579..671
                     /locus_tag="VIB18_001481"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8766478.1"
                     /translation="MIIIDYCNNKRIKIKRKGLSPLQYKTKSFT"
     gene            complement(709..1632)
                     /locus_tag="VIB18_001482"
     CDS             complement(709..1632)
                     /locus_tag="VIB18_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766479.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1625..2695)
                     /locus_tag="VIB18_001483"
     CDS             complement(1625..2695)
                     /locus_tag="VIB18_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766480.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADDSGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2704..3630)
                     /locus_tag="VIB18_001484"
     CDS             complement(2704..3630)
                     /locus_tag="VIB18_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766481.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3630..5132)
                     /locus_tag="VIB18_001485"
     CDS             complement(3630..5132)
                     /locus_tag="VIB18_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766482.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYKKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPFLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5197..7167)
                     /locus_tag="VIB18_001486"
     CDS             complement(5197..7167)
                     /locus_tag="VIB18_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8766483.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYENAKEKWMKAKAKSNAKYAEKLADHVEK"
BASE COUNT         2257 a         1402 c         1338 g         2232 t
ORIGIN      
        1 ttttttgtac ttttttattt gcccgcgttg taaaatgaag tgcaacaaaa aagagaaaaa
       61 gccttgaact acaccccaaa cgttagacaa aaaaatctaa cgttcggggt attttttatg
      121 aaattaagtg atgaaggtac gaaatagaca tcgttaagaa agaaaaaaat acctactatc
      181 caccagagat aaagcaggaa ataatggata acgttttgat agaaggcccg ccacaatacc
      241 aagtatcact tgtttatggc ttgttacatg caggaactct cccaagttga atagcacaat
      301 ataagaaaaa cagttatact gttgagaaaa caagagcaag accatcacaa acaggacgta
      361 aaccaaatga aacctgaaga aatgactaaa ttagagcggc ttcaagaaga aaatgaatat
      421 ctcagaactg aggttgctta cttaaaaaaa acgagggaac tccgtttgaa agaagcaact
      481 ctgcaaagaa gaagacaaaa aaccattata aagaatggac aaagacgagc tctgattaga
      541 ttttctttta agaactgcta aattgactcg ttctacctat tattatcatc gattattgca
      601 acaataaacg tatcaaaata aaacgaaaag gacttagtcc tctacaatac aaaactaaat
      661 cctttactta aaatagagta gccaactttt ggggtcagtg catctctttt acaattcttt
      721 ttgatatttt tcaatttctg cttggtttgc ccaaacaaag tgatttggtt tgatttcaac
      781 cattgatggc ttatctaatg tataatcatg ctggtctgga tgatagacaa caagttcttt
      841 ttgacgctct aaaattggat ctgggatagg cacggctgat aacaaagatt gggtgtaggg
      901 atgaattggg ttattaaaca gttcttctgt ttctgcaact tctacaataa cccctttatg
      961 gataaccgca atacgatctg aaataaagcg aacgactgaa agatcatggg caatgaagag
     1021 ataagtcaaa cctttttcgg cttgcattct tttaagaaga ttcaagacct gtgcgcgaac
     1081 ggaaacgtcc aaagctgaaa tcggttcatc agcaataacg aattcagggt tcattactag
     1141 ggctctagcg ataccgatcc gctgacgttg acctcctgaa aattcatgag ggtagcgcgt
     1201 caaatgctct gatagcaaac caacttcggc catcatgttc ttaatttttt ctttacgttc
     1261 ttcctctgtt ttaaacagat taaaattata aagaccttct gaaatgatgt agtcaacggt
     1321 tgcccgttca ttcaaactag cagcgggatc ttggaaaatc atttgaattt tacgaatgag
     1381 ctcattggct tctgattttg attttctgcc attaattact ttcccatcgt ataaaatttg
     1441 acctgaacta gtatcgttca aaccaataat agcacgacca attgttgttt taccactccc
     1501 agattctcca actaaagaaa aggtttctcc ttttttaata aagaaattag catttttaac
     1561 tgcaacaaat tttttctttc cttctccgaa ggaaatttct aggtctttta cttcgactaa
     1621 tttctcagac atttccttcc tcctgttgtg acattttcct taagattttt tgatgcaaat
     1681 cttgaatgac ttctggtttt tgaacttttg gagcctctgg gtgtaaaagc catgttttgg
     1741 cccaatgagt ctcagatacg ttaatcgccg gaggtgcttt ttcaaagtct aaaaccatag
     1801 catattctga gcgaagtgca aaggcatctc cgataattgg tgaataaagt gatggaggcg
     1861 ttcctggaat agcgtaaagt tcaccagaat catctgccaa ctgcggtaag ctagacagca
     1921 aactccatgt ataggggtgt cttggatcat agaaaatctc ttcgactgtt ccaaattcaa
     1981 caatttctcc tgcatacatg acagccactt tatctgcaat gcttgccaca acacctaaat
     2041 cgtgcgtaat aaagataatg gtgaaatgat attctcgttg aagcgacttc aataactcaa
     2101 cgatttgagc ttgaatagtc acatcaaggg ctgttgttgg ctcatcacag ataagaatat
     2161 ctgggcgaca agctaaagca atagcgataa caatacgttg acgcattcct cctgaatact
     2221 caaatgggta atcttcaaag cgttttttgg catttgggat acccacttta ttcatgtaat
     2281 caagggccat ttctttagct ttggcatgac ttactttttg gtgcttaata atcacttctg
     2341 tgatttggct accgatagtt ttaatgggac taagactggt cattgggtct tggaaaatcg
     2401 ttgcgatttt tgagccgcga atctttgccc actctttatt tgtttttaaa tctgtcaatt
     2461 cttgcccacg atagacaatt gaaccattag caatgcgtcc attagactcc aacatccctg
     2521 taaaggtctt tgttaaaaca gatttacctg agcctgattc ccctacaaaa gcaaggactt
     2581 ctccttcaac aagttccaat gagacgttac ggatagctgt taaaacacga tcacgcacat
     2641 caaattctac caccacatct ttggcagtta agattacatt attttctttt gtcattttaa
     2701 ctcctatcta tgtgaacgtg ggtcactggc atcagccaag ttttgtccga caatgtatag
     2761 tggtaacgat actaaaatca atgttactaa gggaatccaa aagaggtagg catttgttgt
     2821 taagttgctt gaataattag caatcaaacg tcctaaactt ggagtggtgg ttggtaaacc
     2881 aatcccaaag aaggataaga aggcctcaga agatacataa actggtagca tttgtgacaa
     2941 catagtcatg ataactgaaa ccaattgagg caggaggttc ttaacagcaa tcttgtacat
     3001 tggtgttccc aaagtttgac tagcaaggtt gtattctaaa tcacggtaac gcaagatttg
     3061 aacacggatg gagtaggcga caccaatcca tccagtgata cagaaagcta gaatcaaatt
     3121 ccaaaatcct gcacctaatg aataggtcaa aacaatgata ataagcatag aagggatatt
     3181 tgagataatg ttataaattt caatcataac tttatcaaat gctttagaaa ctccccatat
     3241 ggctcctaac actaccccaa tggtgatatt aattagtgtc gctataactg agattaaaat
     3301 agaattacgt gccccatacc aaacaccatc aaacagagat tgcccatttt tgtcggttcc
     3361 aaaccagtac tctgcattcg gccaaatata acgctttgaa aagtcattga tattactaac
     3421 gtcattaaag tcgtagttgg caaacattgg ataaataaag ctcatcatca agactgtcac
     3481 taaaatcacg agcataaaga ctgtagattt tttagaaaaa aactgacgaa acactgattt
     3541 ccagtaagaa taagcagggg tatcaatcac ttcggaggct tcactatcgc gctcaacaaa
     3601 tcgaaattta gatttatcaa tcgattccat tacttacctc ctttttttgt tgacaattta
     3661 atacgtggat cgacaagggt catgacaata tctcctagta aaagtgaaac aattgacaag
     3721 acagtgaaga taaaggttaa tccaacaatc atagaattgt tagcagattt aatagaatca
     3781 attaacattt tacccatacc cgggaaggca aagacagtct ctgttaaggt tgcaccacca
     3841 atagcaagga taatacttgc aggaacccct gacacaattg ggaccatggc atttttgaag
     3901 agatgccctc tgtaaatttc agattctgat aatccttttg aacgcgcaaa acgtacccaa
     3961 tcactggcct gaaggtcaac aagatagcga cggaaccaga taaccgtagt tggaatattt
     4021 aaaattccta aaataagggc tggtaaaata taagatttag gatcagatgc ccccagcatt
     4081 gggaaactat ctggtaaacc aaccatgcca cctaggaagc gaacaacata gataacagca
     4141 atacttggta aagcaagcat gaaggtcatg gtcgctgttg agaaacggtc aaaataggta
     4201 tttttaaacc gagccataaa taaaccaaga ggcaaaccaa cgatatagga aaacataaca
     4261 ccaaaaaaac caattacaaa agaattgtga atcattgatg ggtcgacata attattgatg
     4321 gttttagtgt aggaatctcc cttaccatag tttaccttgg tgatatcatc caatgatttt
     4381 ggatttttgt agctacggct atagatatcc actgacgatt tcttagtgac acctgatggg
     4441 aaggtcacat cttgaagagc tgttcgtcct tgcccttgtg aaataacctg aagaaaagga
     4501 atattgctgt atgttggata agatgttcct aagtttaggg taacaaagtt ttggtgaaga
     4561 taaggaaatt ttccgttagt atagaggaga tatttatgtt ttgtccccga accaacaagt
     4621 gaccagccaa ctgatttatc tttttctaga cgaatatacc tagctaattt tggattatct
     4681 ttatcctgaa tcttccaagg gtgatcaata acaactagat ttgagaaaaa gttccaaaca
     4741 cgttcgtaaa taggaatatt gcgaattgca taaaactgtt tgctagtggg gaagcgtttt
     4801 agctgccagc cattgccaag agaatcaata tacttcttat agatagcttt gttagcacta
     4861 gttgcttctg tcgttacact actatctact ttagaagcat tatcttttaa ttctttgctt
     4921 gaaaaataat tgacataacc catacgttga aaagttagat tttcatacgc tactttttta
     4981 tctggtgttg ttgtcatttt attataatta gggtcttgtt taaagataag gctggtaggt
     5041 actagagtat atacgatggt gtatgttaaa gccgttacca aaactaccga cactaacgat
     5101 cgcatgatac ggtttaaaat gtattttttc atagttatcc tcaatagttc aaaagaactc
     5161 cctcacataa acgagaaagt tcttttgaac atcgttttat ttttcaacgt gatcagctaa
     5221 cttctcagca tattttgcat ttgacttagc ctttgctttc atccattttt cttttgcatt
     5281 ttcgtattgt tttgctgtga caggtttgtc ttgaagtttc attcctttat atgctagagg
     5341 acctttagac cctgcccaag agaagccccc gctaaatgga acggctttag taactcgtgg
     5401 agtgccaccc aatgccacaa ctggaatatc tacggcatta tctgtaaggt aggcttgtgc
     5461 ttttgcgtaa gctttatagc gcgcatcgtt gtcgtctgta attgctgctg cttcatcaag
     5521 aagagtttgg taggtatcaa gacctgcagc tgccacaaca tccttatttt gacctgcttt
     5581 gattccaagt ttttggataa cagatccacc acctactgga ctcatgatgt caaggtaggt
     5641 ccgtggatct tgatagtctg gtccccacca tgatgaaatg atatcgtagt cttgttgttc
     5701 tggggtctca gcatagaagc cttgggcttc gtgagttgat gtttctgttt caagaacatt
     5761 gacaatgaca ttttctttac caagagatgc ttcaacagat tgtttgaaag actgggcttc
     5821 ctgaacagtt gctgcgtttg cttggtcaac agggtaatct aattgaactg ggaaggttac
     5881 accttcagct gtcaaagctt ctttggcttt tgcaaactca gcttttgctt tttcaggatt
     5941 atagaaacca tcttgagcat cagctaagtt aacgtctttc cattcatcac caagttttgc
     6001 catttccttt tcaacttctg aaccaaaatc actttctcca atggtcacaa atgttggtgg
     6061 gacaagcatg ttacgtaagg cttttgtttt agcatcttga cctgcagttt gggcttggaa
     6121 tgacgctcgg tcaaaagcaa actgaatagc ttgacgaaaa tccttgttgt taagagcttt
     6181 cttaccggca tcttgttgtg cagggtcttt cttagtgttt ttgaaagaag tacggttcaa
     6241 attccatgtt aaatgacgga tatctccagt caacattccg taagtaatgt tatcagcata
     6301 gtttttctta gctgatttgt aggtagggtc atttgggtaa agtcgtgcaa cgctgaactc
     6361 acccttgtca aagttcttgt agaacgaacc tgggtctgaa ccatctgagt aagtcaattt
     6421 aacagattct atcccaacat tcttagcatc ccagtagttt tcatttttat ggaattccat
     6481 agatgatttt gaggtgaagg cgctcaagaa gtaagcacca ttaacaagga ttgatgatgg
     6541 atcggttgta ccaaaatctt taccttttga cttcaaaaat ttcgcattaa ctgggaaaag
     6601 cacactataa gttgtttttg aattccagta gctttcaggc ttgttcaaag tatactgaac
     6661 agttttatcg tcaagggctt tgacaccaac ttctttaaaa tctacttcac cattttggta
     6721 agcctttaag ttttttattg aatcttcaac aacgtaaaga gcatctgatt tatcgtcaac
     6781 cgcgtgcttc aaaccagtca caaaatcttc tgctgttact ggggcatatt cttcaccatc
     6841 agccgtatac caagagacac catcgcgaag agtataagta taagtcagac cgtcttttga
     6901 aaccttccaa tctttagcaa gtgatggtac taaattacca tactcatcgt tttccaaaag
     6961 accatcaacc atttgtgtta tcacatcagt cgttccaccg ccattagtca aaatataatc
     7021 caatgatttt ggatcgttaa caaaaacgta cttgtaggtt tttgtagctt ctgagccacc
     7081 tgaagcattt ttattaccac aagctgccaa agcggatact gacaagatcg caacacttac
     7141 agctgccaac catttacttt tcttcataaa agtcacccct aaactttatt tttcattttt
     7201 tggcaattgc taaatgaaat tggttaatt
//
LOCUS       DAUGSW010000053         7105 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUGSW010000053 DAUGSW010000000
VERSION     DAUGSW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7105
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.053"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(90..362)
                     /locus_tag="VIB18_001487"
     CDS             complement(90..362)
                     /locus_tag="VIB18_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEQ8766484.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            complement(379..1746)
                     /gene="dnaB"
                     /locus_tag="VIB18_001488"
     CDS             complement(379..1746)
                     /gene="dnaB"
                     /locus_tag="VIB18_001488"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEQ8766485.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            complement(1776..2228)
                     /gene="rplI"
                     /locus_tag="VIB18_001489"
     CDS             complement(1776..2228)
                     /gene="rplI"
                     /locus_tag="VIB18_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEQ8766486.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            complement(2225..4201)
                     /locus_tag="VIB18_001490"
     CDS             complement(2225..4201)
                     /locus_tag="VIB18_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEQ8766487.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            complement(4291..6189)
                     /gene="mnmG"
                     /locus_tag="VIB18_001491"
     CDS             complement(4291..6189)
                     /gene="mnmG"
                     /locus_tag="VIB18_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEQ8766488.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            complement(6313..6630)
                     /locus_tag="VIB18_001492"
     CDS             complement(6313..6630)
                     /locus_tag="VIB18_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8766489.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRAKVNQLAFMVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFMNGFQSIN
                     WIK"
BASE COUNT         2179 a         1487 c         1096 g         2343 t
ORIGIN      
        1 caaaataaaa agaatacagg cagaataatc ttctatcgct aataattata tcaatttatt
       61 gtaaagaaaa agcctctatg aggcaaaaat caatctaaat aacgaattaa tgttttttct
      121 gtcaaaatat ctgaataggt gtatgattcg acataagaat tatcaattgc tcctggagta
      181 tcagagctat cactatactc aatgataaag agtgaactgt aaacttcaat aagcctacca
      241 attttatttt tttcccgttt ccgtccattc tcaagggtta attctactaa ctgtccttca
      301 tgggctctta tgtcctcttt aatttttttc atttttgcaa catctgtaaa tgcatcgctc
      361 attttttgtc tctctttctt atctttcttc aaactgggct atacttgaga atttgttgta
      421 ttctttttgg aacatcagtt tgactgttcc acgcgcccca gctctatttt tctcgaggat
      481 aacttcaatt gtgttatctt caacagcttc ttcagcatca tcaccttctt tacggtaata
      541 atcgtcccgg tataagaagg ctacaatatc ggcatcctgc tcaatagatc ctgattcacg
      601 aatatctgat aaaactggtc gtttatcttg cctttgctca acgccacgag aaagctgact
      661 tagggcaata actggtactt tcaattcttt agctaggatt ttaagctgtc ttgaaatatc
      721 tgaaacctct tgctgacgat tttcgggttt agttcctgta atcaactgta agtagtcaat
      781 tacgataaga cctaaaccac catccacttc ttgagacaat ttccgtgatc ttgcgcggat
      841 ttcagtaatt ttaatcccgg gcgtatcgtc aatataaatc ggtgcttctg ccaaagctcc
      901 ctgagcaatt gttacattat tccaatcctg atctgtgagt tgccctgttc ttaaactgtg
      961 cgaatcaacc attccttctg ctgcaagcat acgatctact aaactttcag cacccatttc
     1021 caaagaaaaa atagcaacag tctttttttg cttagtcccc acattttgcg caatattaag
     1081 aacaaaggca gtcttcccca ctgctggccg agcagctaaa ataactaatt gatctgggtg
     1141 taaacctgtt gtaatcttgt caaggtctct aaaaccagtt ggtaaacctg taacatttga
     1201 agtctgctta gaacgtgctt ctaaagcctc gtaattaact tttagcacat ctgaaatttt
     1261 gcgaaatcca ctacgattac tatgttcatt gagttcaatt aaagctctct caactccagc
     1321 gataacctct tctggtttta aaatttcatc ataagctagg ttgacagatt ctgtcaacct
     1381 agcaataata tcacgcaaca tagctttctc agctacaatt ttagcataat attctgcatt
     1441 agcactagtt gggacactat taactagttc aacaatatag gataagccac caatactttg
     1501 cagatcatct tgatcatcta ggattgttct tatagtggtt gcatcaatgg catcattacg
     1561 atcgctgagg gtaatcattg cccgaaagat aattttatga gcgtacttat aaaaatcgtc
     1621 tggactgata aattctctca ctgcaatcag cttatcaggt gagataaaga ttgacccaag
     1681 aacagattgc tccgctagta aatcttgggg ttgaactcgt aattcagcta cttcaggcaa
     1741 cctcataacc tccaaatctt gtgatgtttt ttatattatg cttctgtgat agccaattta
     1801 atctcagctg ttacttcctt atgtaatttc acaggaactt caattagacc aatggcgcgg
     1861 ataggatgat ctaaaacaat atgacgttta tcaactttca caccaaattg cttttgcaat
     1921 tcttctgaaa tctttttagc tgtgatggaa ccaaatgtac gtccatctgg gccaactttt
     1981 tcttgaaatt gaacacgtgt tttgtcctca tccaaaacag ccttgacagc ttgagcttct
     2041 gctaatattt cagcttgagc tttttcttca gctttttgtt ttccttttaa ttcaccgatg
     2101 ctttgactag ttgcttcttt agctaaattt ttcttaataa ggaaattttg agcatagcct
     2161 gttgggacct ctttgatttc tcctttttta ccttttcctt ttacatctgc taaaaaaata
     2221 actttcatga ttctacttct cctgtttctt tcattgtcat attaatagtt ttcaataata
     2281 agtgcttcgc ttggggaaga ctgatatccg ttaactgaca ggcagcaaga ttaaagtggc
     2341 ctcctccacc taatttttcc atcacacgtt gaacattgat tttactacga cttctagctg
     2401 aaatagcaat cttatgagaa gctgtttcaa ctaatacaaa gctagcctca acgtgagcca
     2461 ttgacagtat cgtatctgca gctttactag caataacatt gctataaaga tgattttttt
     2521 ctcctgcagc tacaatgata ctgtcaccaa gacgttctcc ttgtaaaata atttcattta
     2581 tttgcttata ttcttcaaaa tctgttgcgg atatattttg aatttcaaca ctatcacttc
     2641 ctttacttct taagtaacta gcgacatcaa aggtacgact tgtcactcgc gtagaaaaat
     2701 ttttagtatc aagcataata cctgccatta aaacactggc ttggatctta tttaaacgtt
     2761 ttttagcatt ttgaaattga attaactcag tgacgagctc cgcagcacta cttgctccac
     2821 tttcaataaa agttaagata gcattatcag gaaaatcatc atctcttctg tgatgatcaa
     2881 ctacaataac attttgaaac tgttcataaa attctttaga aagtgttaaa gatatcttag
     2941 aatgatcaac cattactaaa agtgatcttg gagtcactaa acccattgct tgagaaacac
     3001 tgattagacg agtctttccg tcagcctgca atcgctcaat agccctttca atatctggac
     3061 tcatctcatc tggattgtaa acggcaaaac tattttcaat aatgttacct gcgaaaaatt
     3121 gcataccaac agctgaacct agtgcatcca tatcaagttt cctatgtcca acaataaaaa
     3181 cattgtccac catcttgatt cgatctgaaa tagctgtcat catagcacgg gtacgtgttc
     3241 ttgaacgttt aactgtagaa acagaccctc ccccgaaata aattggattc gtatgatccg
     3301 cattttcacg aatgacaatc tgatcaccac cacgaacaag cgcaatatta agattctcaa
     3361 gagctacctg tccaatctgg ctatgatttt cttcaccaaa agaaattcct atgctgagtg
     3421 ttaaagggcg ctgagcatct tgagcttctt tacgaaactc ttctaagaca gaaaatttat
     3481 tatccatcaa atcatttaat gttttaaagt ctgtaaagaa atagtagcga tccatattaa
     3541 cacgacggta aaaaatccgt tttgactcca taaactcatc aatgaagtta gctacaaatg
     3601 aattaatttt tgaggtatct gcatctgata aatcatcagt gatatcatca taattatcaa
     3661 ccgaaataat gccaacaacc ggtcttaaca tactagcatc agctaattgc ctgtttccca
     3721 caaagctatc aaaaaaataa aaaattcctg atgatacatc aatataagaa gtgtatttat
     3781 taccagaaac ttcaaatgtt tgagaaatat cttcacgacg tttttccgta ataatttgct
     3841 gaatcaaact gttttgtata aaaccctctt cagttgtaaa aattaattct gcataaggat
     3901 tataccattc tacagcgttg gtctcttgat caaattgaac tactccaaca ggcatattat
     3961 caagtagcgt ttttaggtta tcttctgttt gttcatttaa gagctcaata tgagctaagt
     4021 ctgataattg ataagcttct ttttgatacc ataaaagagc aacaacaaat agcaaaacga
     4081 gaaaaatagc taataatatt aatatttttg attgcataat actgacacaa agtgccagta
     4141 gtccaaataa aatcaatccc atcataatca aatgaatggt ttcaaaacga aattttttca
     4201 tcttataacc tcttaagcac acattatacc ataaaaaagc cctgaaatac agagcttcca
     4261 cttgctttga gattacaatt tcatttccat ttaatatttt cgatgagctt ttccgtttcc
     4321 ctctaaataa atcatcaaga tactgatgtc cgcaggattg actcctgaaa tacgactagc
     4381 ttgtccaatt gtttcaggat taattttctt aaatttctga cgcgcctcag ttgcaataga
     4441 atcaatagca tcccaatcaa tatttgcagg aatacgtttt tcttccatgc gtttcatctt
     4501 agcaacctga tctaaagctt tgcgaatata gccttcgtac ttgatttctg tttctaaaag
     4561 ttcaatgatt ttagcatcta aatcttcagc cgcaggacca acaaaagaga ctgcagtcgc
     4621 ataatcaatt tctgggcgac gcataaattc tttagctgtc atagcatccg tcaatggttt
     4681 aaaaccaagt tcctgcacac gatcgttggt tgcttttact ggttttaatt tgatactgtt
     4741 cagacgtttt aattcgttat caaattggtt tttcttaatt tcgaaggcct tccaacgctc
     4801 atcatcaacc aacccaatgt cgcgaccaat ctctgtcaaa cgcatatcag cgttgtcatg
     4861 acgtaaaatc aaacgatact cagctcgcga tgtcaacaat cgataaggtt ccaaggttcc
     4921 tttggtaacc aaatcgtcaa tcataacgcc aatataggca tcgctccgtt tcaaaataag
     4981 ttctggctta ccttgaactt tcaaagcagc attgattcca gcaataagtc cttggccagc
     5041 agcctcttca tacccagaag ttccattagt ttgcccagcc gtaaagagtc ctgaaattag
     5101 cttggtttca agtgtggcac gtagctggtg aggtaaaaca atatcatatt caatagcata
     5161 accagtgcgc atcatttcag ccttttcaag tcctttgatc gaatgaatca aatctttttg
     5221 gacatcttct ggaagactcg ttgacaaccc ttgaacatac acttcttctg tatcacgccc
     5281 ctctggctct aagaaaagtt gatgacgttc tttatcagca aagcgaacaa tcttatcttc
     5341 aatagatggg cagtaacgag ggcctacacc tttaacaatg ccagaaaaca tcggtgctct
     5401 gtaaaggttc tgattaatga tatcatgact agtttgatta gtataagtca accagcaggg
     5461 aatttgatct ttgaggtaat cagcatcttt tgacataaat gaaaaatgat taggtttatc
     5521 atcacctggc tgaatttccg tttgatcgta attaatagaa gatgctttga cacgaggagg
     5581 cgttcctgtt ttgaatctgc caatttctaa gccgagtttt tttaaattat ctgctaaggt
     5641 tactgatgcc aaactattat taggcccaga agaatatttg agttctccta aaataatttc
     5701 gccacgcaga gctgttcctg ttgtcactac aactgcctta gctgcaaact tttgtcctgt
     5761 ggctgttaaa acacctacaa ctcgtccatc ttcaactaga atatcatcaa tcatcgtttg
     5821 gcgaagagtc aaattagcct gtttttcaac cgtatgtttc atctcacgcg catacaggga
     5881 tttatctgct tgagctcgga gagcgcgtac agctggtccc ttacctgtat taagcatttt
     5941 catctggata taggttttat caatattttt acccatttcg ccgccaagag catcgatttc
     6001 tcgtactact atccctttgg cagatcctcc aatagaagga ttacacggca taaaagccaa
     6061 catatcaagg ttgattgttg ccaataaagt tttacaaccc atacgactag tggccaaact
     6121 ggcttcaaca ccagcatgac ctgcacctat gacaatgacg tcatagcttt ctgtaaattc
     6181 atgtgtcatt tttttaaaat cctttatttc agtctattca tttaaaatca tacgctttag
     6241 tttagccttc aatgcggaca atatgtcctg gccatttagc caactcggtt tgtaaaaact
     6301 caggaacaag attcatttga tccagttgat tgattggaat ccattcataa acctgtcgct
     6361 tgcattctct atcatttcta gtttagggtc ttctaagggg cttaccaaat aatgaaattc
     6421 aatattatgc cagaaaacat catcgatatc aaaatgattc tcaaccataa aagccagttg
     6481 attaacctta gctcgaatac caacttcctc taaggtttca cgtaaaacag tttcatgcgt
     6541 tttttcacct accaaacttg taccaccaat ggtgtaatat tggtcagctg catctctagt
     6601 taaaaaattc ttaccatttc taacaatcaa gcgctagctc gtaaactaaa gttatctgac
     6661 ctctagtgat tttaaattcc agtcctatta gccatctcat ttctagagct aaaccataaa
     6721 agggccaaaa ccctagaaga ttgcaggaca aaaaaaccta caactttcat gagctttgac
     6781 catcattccg attgttacta tctattttaa aaaaatgatt agtgattgtc aatattgatt
     6841 tcatcacaga cctttacagt aatgtcaatg tttttacagc tctgtcaatc tattgtaatg
     6901 tttttaaaat gattacaaaa gtatcactat gtctaatcta gcgaggcgag aaataaaaat
     6961 gtcatcagta ttatcatacg attttttgat atcttctaaa gtagtaaaat acagataccg
     7021 ttgtttctaa gtctacaagt aagaacgccg ataacaaaac cataaaagta taactagaaa
     7081 tttccaataa ttttttacac attta
//
LOCUS       DAUGSW010000054         6856 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUGSW010000054 DAUGSW010000000
VERSION     DAUGSW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6856
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.054"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            154..927
                     /gene="cfa"
                     /locus_tag="VIB18_001493"
     CDS             154..927
                     /gene="cfa"
                     /locus_tag="VIB18_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEQ8766490.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NFQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
     gene            complement(1297..2532)
                     /locus_tag="VIB18_001494"
     CDS             complement(1297..2532)
                     /locus_tag="VIB18_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEQ8766491.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLITSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVSVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQ
                     ITPIAKRQLHHTHYRIVKM"
     gene            complement(2652..3974)
                     /locus_tag="VIB18_001495"
     CDS             complement(2652..3974)
                     /locus_tag="VIB18_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEQ8766492.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDDGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFVLM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(4102..4188)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            4505..6823
                     /gene="pcrA"
                     /locus_tag="VIB18_001496"
     CDS             4505..6823
                     /gene="pcrA"
                     /locus_tag="VIB18_001496"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEQ8766493.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANIRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
BASE COUNT         2307 a         1280 c         1343 g         1926 t
ORIGIN      
        1 tgattatttt tgtgaaatcc tcttattttc tggaaattaa agaaatattg accttagtaa
       61 aaacaagtag tatgataacg ttataagcgc ttataaatta atttaacttc acttaactat
      121 ttaaataggt ttattatatt caggaggaat aatatgaaac ccaaacacct tctctgtctt
      181 tcaacagttg ttgctggatt agctttattt tcaactatga cgcactcagt tttagctgat
      241 gatgcttcaa atcccgatac tattttaatg aataacaacc aagcaaattt tcaaagagat
      301 gctctagtgc aaaagcttga tgagggacat caacaattag aagctattaa acatgaagct
      361 aaaggtactg atattgaggc tactgttaac aaagctatcg atgctgttga tcacatgaag
      421 agttctatac gcttcaatac tgaaacgatc tatgatttta gttcaattgg ggcaagagta
      481 gaagcattat cagatgctat caaagcaatc gtattttcca caacccaatt aactcataaa
      541 gtagaaaaag cgcatactga tatggggttt gctattacta aattagtcat tcgtattata
      601 gatccatttg catctgttga cgctatcaaa gctcaagtac aagaaattaa agcacttgag
      661 gaaaaagtta tcaattatcc tgatttacag ccaacagacc gtgctactat ctatactaaa
      721 gctaaactaa ataaagctat ttggaacact cgtttagaaa gagataaaaa ggttttgggg
      781 atcaaaccat ttgacgttta caatagactt aacaaagcta tcacacatgc ggttggtgtc
      841 caactaaatc cgacaaccac tgttcaacaa gttgacgatg aagttattgc tgtgcaaaat
      901 gctttggaaa cagctcttaa gtcatagagt gtataagtaa tgtgttgtat aggtagatga
      961 ttatattagg atatagaata ggtaaagatt ttaaatatct taccattgta gagtttgagg
     1021 tgatgttctc ataaacaatg agtcacctgt agcccttttt gcctttaaca tgatgtacca
     1081 atttaaggta ttgttcaacc gtcactattg aatcttgttt aacctcctaa actaataaga
     1141 ttcaatatga aaacgtgtat tcttaaaaaa atccctatga tctgtttaaa aacaaattgt
     1201 agggattttt ttaactattt aacttattat tttgggacta ggaatcgctt taggaatatc
     1261 atgaagtata gttatgttgt aagataagta atatttttac atttttacaa tacgatagtg
     1321 tgtgtgatgt aattgtctct tagcgatagg ggtaatttgg tggaagagta aggaccaaga
     1381 ttcatgacgc ctccaaatac tggtacgttg attgccattt aattggtaag ttaccaacat
     1441 cgttttttga ctaatggatt caatctgaaa atggttgaag ttacttggat aataaatttc
     1501 ttggttcaaa aattgttcat agttaactgt ttggccattc gcatcaatca gttggaaaga
     1561 cttagcaatg tagtggtcat agtcaggaac cttactcaaa attaattttt cgtagcggta
     1621 gagctttttg gcgacattat caaaaatctc ttcttcggga atcatggcag gctcaacgtg
     1681 aatgtcaatg tcataaatag aaaattggtc actcaataac tgctccactt tctctgtaat
     1741 agagtgactt tcatagactg aaagatcagg attcatttca agtacaatat caagatagac
     1801 attgctacca taggtcctag ctcgttgaga cttaacggag acaattttag ggatttctaa
     1861 aatggctttt tcgtattttt tcaaatgacg gctatcaaat ccatcagata aactaaacga
     1921 actttccata aagatatcaa aagctgtttt aagaataaag aacgtaatga tcatagcagc
     1981 tatatgatcg ataactggta aatgcaaaga agctgctata atagcaattg atgttccgat
     2041 agaagtaaca gcatcagcta gattatcctt agaagcagcg actaaggcac tggattttac
     2101 acgtttggaa agacgtttgt taaagacata aacccctaac ataacaaaag ctgaaacgat
     2161 accgacaata gccccaagag ggtcaatatc aacttgctga ccactaaaga tacttttaat
     2221 tgtgtgaatc agtacttgga aacctacaag aaacataata aaagaagtga taaggctgga
     2281 taagtcttca attttccaat gaccaaattt atgattggca tcggctggtt ggctagctaa
     2341 gtgaagacca ataagcaggg ctacatttcc cacaatatcc gataaattgt taaatccatc
     2401 agcaataagg gaacttgcat ttaacaaata accagctaat aatttggcaa cactaagcaa
     2461 caagtagaca ataatactaa cgattgggcc ctttctggct agttttaaat ttgcaatcgg
     2521 atcctgtgtc ataataactc ctttgatttc aactttatat tataccataa aaaggggctt
     2581 aagaaaaaag cctagcttct tgaacttggc agaagaagac taggtataac tgggtagtac
     2641 taacgtcata tttacttaat aaagtaatgc ttggtttcta aaataacaac tggcgagaga
     2701 gctaggaggg caatcaggtt aggaagtgcc attaaaccat tgacaatatc agccaaaacc
     2761 caaatcagtt ctaacttaag gaagcctcct aggcctacca ttaagacaaa gacaatacgg
     2821 aagtaggtga gatgtgtaat gccaaagagg aattcaaagc agcgttctcc ataataactc
     2881 catcctaaaa tcgttgtaaa ggcgaagaga actagggaaa aggttaggcc aaaagtccct
     2941 aaatttccaa acacagtggc aaaggcagat tgggtcagag gagccccttc gagctgccca
     3001 gtccattggc ctgttactaa aatagatagg ccggttaggg tacagataat aatcgtatca
     3061 ataaaagttc ctgtcatgga gatcagtccc tgctccacgg gttcattggt tttagctgct
     3121 gctgcagcaa taggtgcaga tcctagtcca gactcattgg agaagacacc gcgtgcaatt
     3181 cctttttgaa tggcatcctt catgagactt ccagcaaagc ctccaatagc agctgtcgga
     3241 gtgaaggctg attgaaagac taaacgaata acaggaagta gctgctggta gtgactaaaa
     3301 ataactgcta aactagatag aatataaaaa atagccataa aaggaacgac tttttcagcc
     3361 actttggaaa tggaatgaat gccaccaaaa ataatggcag ccacaaagat agctaaaaca
     3421 atactgacca tttgtgggga taagccaaag ctatgaccta aagacgaggt gatcgagttc
     3481 acttgagcaa aggttcctat tccaaatagg gcaactagga tccctgaacc cgcaaaaaga
     3541 atggctaagg gtttccattt tgtccccatg ccattaacaa tatagtacat aggaccacca
     3601 gaaatatgac cgttggcatc ctttgtacgg tatttaatcg ctagtacccc ttcagcgtac
     3661 ttagtggcca ttccaaaaaa agcggcaacc cacatccaaa agagcgctcc aggaccacca
     3721 gacttgatag cagtggcaac cccaacaatg ttaccagttc cgacagtagc ggcaagggca
     3781 gttgcaagag cagcaaagga tgaaatatct ccgtgaccat catcatctga aaaaataagt
     3841 ttaaaagctc ttggtagttt taagatttgg atgaggccta aacgactcgt aaggtaaata
     3901 ccagtaccaa ccagtaagat taacaagggc ggtccccaaa caaggttatc aattaattta
     3961 acgagtgcta tcatctttct ctcctaaaag tcatcgaaga cgccaaaaga aaaaagctat
     4021 ctctttcttt gagacaactt ctgaagcaat gataaaacag caaacacaaa aaagactaag
     4081 actgttctta atggtgtttg tattttacct tctgtccttt tgcctgagag attgagcagt
     4141 atgccttgcc ccttcggcgc ctaataaggt ctctccagaa gtccgtccat caaacagtcc
     4201 cgttcaaaaa ctgaacacct gagagtataa ctccttcggc gaaaaaaatt cttctcctgc
     4261 atgacatcat tcggtttatt aaattaggac tatcatacct caaaaaacga atgaagtcaa
     4321 ccaaaatagc aaaaaaaaat aaggaatgct ttaagaaatc gctattattt ttaaatatct
     4381 gaacctaaac tagaaaaaag aaatctcttt acttttgggg tcttctttgc tattttcctt
     4441 ggaaacatga tataatttta aggttgataa aagagatgtc actgaacgag attaaggaga
     4501 aagcatgaat cctttattaa atggaatgaa tgatcggcag gcacaagctg ttcaaacaac
     4561 tgaaggcccc ttattgatta tggcgggggc tggttctggt aaaacaaggg tactgaccca
     4621 tcgtattgcc tatttaattg atgaaaaatt tgtcaatcct tggaatattt tagctattac
     4681 ctttactaat aaggctgcgc gtgaaatgaa agaaagagcc ttggccttaa atccagctac
     4741 taaagatacc ttaattgcta cctttcactc catgtgtgta cggattctac gtcgtgaggc
     4801 tgatcacatt ggttacaacc gaaacttcac aatcgtggat ccaggtgagc aacgaacgtt
     4861 gatgaagcgc attttaaaac aattaaatat agaccctaaa aagtggaatg aacgctctat
     4921 tttaggaact atttcaaacg ctaaaaatga tttgcttgat gaaaagggat acgaggcaca
     4981 ggctgctgat atgtatagtc aaatcgtagc gaggtgttac aaagcttatc aggaagaatt
     5041 acgacgtagc gaagcacttg actttgatga tttaatcatg atgacgctac gcctgtttga
     5101 cgctaatcct gacgtgttag cttattacca gcagcgttac caatacattc atgtggatga
     5161 gtaccaagat accaaccatg ctcaatatca gctaattaaa ttgctagctt ctcgctttaa
     5221 aaatatttgc gttgttggag acgctgatca gtctatctat ggttggcggg gagctgacat
     5281 gcaaaatatt cttgattttg aaaaagatta cccagatgct aaggtagtgc ttttagaaga
     5341 aaactatcgc tctaccaaga aaattctgca agcagctaac gacgtgatta acaataaccg
     5401 taatcgccgt cctaagaaac tttggacaca aaatgcggat ggggaacaac tggtttatta
     5461 ccgggcaaat gatgagcgag atgaggcagt atttgtggcc tcaaccatta gcaatatgag
     5521 tcaagagctt ggaaaaaact tcaaagattt cgctgtttta taccgtacca atgcccaatc
     5581 tcggaccatt gaagaagcac tcttaaaatc caatattcct tacaccatgg ttggaggcac
     5641 caagttttac agccgtaaag aaattcggga tttgattgcc tatttaacca ttgttgctaa
     5701 ccctgctgat aatatttctt ttgagcggat tgtgaatgag cctaaacgag gtgttggtcc
     5761 aggaacgctt gataaactgc gtcagtttgc ctatgagagt gaccagtctt tattagaagc
     5821 agcttcaaat ctattgatgt cccccttgaa aggtaaagca gcacaagcta tcatggactt
     5881 ggccaatatt ctcggtcagc tacgtcaaga cctagatcag atgagtatca ctgacttagc
     5941 agaagctttg ttagaaaaaa caggttattt agatagctta cgcctgcaaa atacattgga
     6001 aagccaagcc cgtatcgaaa atatcgaaga attcttatct gttaccaaaa attttgacga
     6061 gtcaagtgcc tctcaagaag aagacgaaac cggtgttgat cgcttgggac gttttttaaa
     6121 cgatttagca ctgattgctg atacagatga ctcccaagca gaagctgctg aagtaacctt
     6181 aatgacccta catgctgcca aaggcttgga gttccctgtt gttttcttaa ttggtatgga
     6241 agaaggtgtc ttccccttat cacgtgcctc tgaagatcca gatgaattgg aagaagaaag
     6301 acgtttagct tatgtcggaa tcacaagagc tgaagaagtt ctctttatga ccaatgccaa
     6361 catcagaacc ctctttggta aaagtagtta taaccgtcca acacgcttct tgaaagaaat
     6421 ttcagaggaa ctactctctt ataaaggatt ggcaagacca gcacaatctt catttggtgt
     6481 gcgtttttct actgaaacac acacacagtt tggacaaggg atgagcctat cagaagcctt
     6541 acaagctcga aaggcccagg ctcaagtaag acaatcagca cagccaatgc aggcacatac
     6601 gataccatca gcttcaacta gctcagtttt accgtttggt tctaatagct ctgtagaaga
     6661 ggtcacttgg cagattggcg atatcgctca ccataaaaaa tggggagacg ggactgtgct
     6721 tgaggtttca ggctccggaa aaacgatgga attgaaaatc aaatttccag aagttggtct
     6781 aaagaaatta ctagcaagtg ttgctcctat tgagaaaaaa taagaaaaaa atgagcttcc
     6841 tactatataa gtgagt
//
LOCUS       DAUGSW010000055         6429 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUGSW010000055 DAUGSW010000000
VERSION     DAUGSW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6429
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.055"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            603..1214
                     /gene="rpsD"
                     /locus_tag="VIB18_001497"
     CDS             603..1214
                     /gene="rpsD"
                     /locus_tag="VIB18_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEQ8766494.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1364..1900)
                     /locus_tag="VIB18_001498"
     CDS             complement(1364..1900)
                     /locus_tag="VIB18_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8766495.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFRTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTVPK"
     gene            2035..4308
                     /locus_tag="VIB18_001499"
     CDS             2035..4308
                     /locus_tag="VIB18_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEQ8766496.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSIWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNANLSTMQVPKLNTDELGNNLAAIAQAAQQLLV
                     KEAAAHKEQLAVLQATSAYQSLTAEQQGELTAALTQTDKGEAVAPAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADG
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNTKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGHPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(4424..5497)
                     /locus_tag="VIB18_001500"
     CDS             complement(4424..5497)
                     /locus_tag="VIB18_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEQ8766497.1"
                     /translation="MKNISRKCFMTSVVCIVLGAILLGAGYATGGLQDIKHQTAPKKV
                     IQTFDHVTALDIDTNFSTITVETGPVKKPTVTYYTHSKFIDPLEIKIENETLHISEKP
                     RDVIITGGIELIGFGLNKSDRNHNYRTTTITLPKGTSLKELKGSSMPQATISDLTVQD
                     LEFSGGLTLLNTRIKKGKVFGTFNATDSLLANLELKADYSLSSLTNSSLENGTISLGH
                     GQLTTKNTNLKSVTIQSLSPGGVEAEETSLENVTFTVTSEQENEETNDNGAIFTAHAL
                     TLKGTNTITGGDIDVDITLTKAKAIAYRARTENGKVSLGSQLTPAKIGKESTSDVISY
                     VAENKAATGNLTVNLNKGDITIK"
     gene            complement(5494..6081)
                     /locus_tag="VIB18_001501"
     CDS             complement(5494..6081)
                     /locus_tag="VIB18_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEQ8766498.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEALEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATALLRFSGRAFVAFIKWISHKKGAQA"
     gene            complement(6068..6394)
                     /locus_tag="VIB18_001502"
     CDS             complement(6068..6394)
                     /locus_tag="VIB18_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEQ8766499.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
BASE COUNT         1953 a         1202 c         1243 g         2031 t
ORIGIN      
        1 ttgaaggaaa aaagaggtct tcaccatggt taagcaaatg atcttagtat taaggttaaa
       61 agattatcgt gaaataaagt tttgacacaa gtgtaattga tagaggaact tgaagtatcc
      121 ggtaaaacta tcttgaagtg aaaaaacgag taaacctccc ctgataaata caatatacta
      181 gccatttcag agcaattaag agtttccagt gaagtgcttt tgatagagag ctaagaaaaa
      241 acagtcaagg tttaagaact gcaaattagc atttaaatta ttttttgtta atgacagttg
      301 tctttattac cataactata acttcttata atatagtctt cttaattcat cagtggtggt
      361 tcgtctcata tctgacctta aaatattaaa ctgatcatca gatgatagat agactgactt
      421 tacaaaacaa ctttcttatg gtaaactgtt ctttgtgcga aataacagca gaaaaatatg
      481 aagctcgtca acaggtggtt atctattcaa gtaacctttg ctgtttaggc gaaaaccccc
      541 tgcacgaatc aggatttttt aaaccgttat ttcctcaaaa aatttagagg aggacatgta
      601 atatgtcacg ttatactggt ccatcatgga aacaatcacg tcgccttggt ttatcactta
      661 caggcacagg taaagaattg gcacgtcgta actacgttcc tggtcaacac ggtccaaaca
      721 accgtagcaa actctcagaa tatggtttgc agttagctga gaaacaaaaa cttcgtttct
      781 catacggttt aggtgaaaaa caattccgta acttgttcgt tcaagctaca aaaatcaaag
      841 aaggaactct tggtttcaac tttatggttc ttttagaacg tcgtcttgac aacgttgttt
      901 accgtctagg tttagcaact actcgtcgtc aagcacgtca attcgttaac cacggtcaca
      961 tccttgttga cggtaaacgc gttgatatcc cttcataccg cgttgatcca ggtcaagtga
     1021 tttcagttcg cgaaaaatca atgaaagtac ctgcaattct tgaagctgtt gaagctactc
     1081 ttggacgtcc agctttcgta tcatttgatg ctgaaaaact tgaaggttca ttgactcgcc
     1141 ttccagaacg cgatgaaatt aacccagaaa tcaatgaagc acttgtcgtt gaattctata
     1201 acaaaatgct ttaattttaa gattaaactt acaaaaagcc tatttaatag gcttttttta
     1261 tatctcataa caaatttatc ctgatccctt cattttacta tggcttctaa aaaagttatc
     1321 actaaggctg atgacttgta aaatgatact ttcgtaaggg ttactattta ggtaccgtaa
     1381 gcattttgag aacgaattgt gtcatttctt gaggtgattc ttttttacct ttagcaatcc
     1441 aactttgaca gacaccaaaa aaagcatggg ctaagtagat actttggtat tctttttccg
     1501 tttgagataa ctcttcggta cggaacttgt cctgtaaatc agtagtgatg agtaggcgaa
     1561 ctttattgat gataaaggcc tgtatttctt tggtaccgtt agcagacaaa agggaagaga
     1621 gaagctgttc tctttggaga aattcaaata cttcaaggaa ggcttgttct ttattttgat
     1681 attttttctc aaaaatatat tctaatttgt gaaaaaaggt ttgctgataa tagtcaatca
     1741 tttcatattt atctttatag tgtgtgtaaa aactagagcg actaattcca gctcttttag
     1801 ataatttaac tgtggtaata tcgtcaaaac tttcggtttt tagtaacata accattgctt
     1861 ttaaaattgc ttgcttcgta ttttctttac ggttgaccat ctaccatctc tccttttgaa
     1921 cacttttaga cataatgtcc aaaagtgaat ttttttctct tgtaaattta aatttaaatt
     1981 gtataatata ttttatcata atttttgaac agtatgtcca ttttaggaga aaatatgtta
     2041 gaagaattga aaacacttat taaaaatcca aaattaatga ttacaatgat tggtgtggcc
     2101 ctagtgcctg ccttatataa tttatccttt ctaggctcaa tttgggatcc ttatggtcgg
     2161 gtcaatgacc ttcccattgc tgttgttaat catgataagc ctgcaaagag agctgataag
     2221 tcattgacaa ttgggaatga tatggtggac aagatgtcta aaagtaaaga tttagagtat
     2281 cattttgtct cagctaagca agctcaagag ggacttaaag aaggtgatta ttatatggtt
     2341 attactttac ccgaagatct ttctcaacgg gcagcaacct tattaaatcc cgaaccccaa
     2401 aaattaacta tccgttacca aacgagtaaa ggacatggaa tggtcgctgc taagatgggg
     2461 gaaacagcga tggctaagct gaaagagtct gtttcgcaaa acattacgaa gacttatacc
     2521 tcagcagttt ttagcagtat gacagacctc caatcaggat taaaagaagc ctcagctgga
     2581 agtcaggcac ttgcttcagg agcgaagacc gctcaggcgg ggagtcaaac actttcgaca
     2641 aacttagcag ccttaacggg tgctagccaa cagtttcaac aaggtactgg tcgattgaca
     2701 tcaggtttga ctacctatac agatggtgtc aaccaagtca agaatgggtt aggaacatta
     2761 tcaacggaca tccccaatta tctgaatggg gtttctaggt tatcccaggg agcttctcag
     2821 cttaatcagg gtctttcaca gttgacacaa gcaaccacac tttctgacga gaaagctaag
     2881 ggaattcaat ccttaattgt aggactacca gtcctaaatc aaggcattca gcaactaaat
     2941 gcaaatctct caacgatgca ggtaccaaaa cttaataccg atgagttagg gaataacttg
     3001 gctgccattg ctcaagctgc gcaacagtta cttgttaaag aagctgctgc tcacaaggaa
     3061 caactagcag tcttacaagc cactagcgct tatcagtcac taactgctga gcaacaaggg
     3121 gaattaactg ctgctcttac tcaaactgat aagggtgaag ctgtggctcc tgctcaaacg
     3181 attttaagtt ctgttcaaac tttgtcaaca agtttacagt ctctctctca agaagatcag
     3241 tcaaaacagt tggagcaact taaggaagct gttgcacaga ttgctaatca atccaatcaa
     3301 gctttgccgg gagcaagttc tgctttaact gaattatcaa cgggattagc aaaggtaaat
     3361 ggtagcttaa atcaacaagt tctaccagga agtaatcaat tgacaacagg attagcacaa
     3421 ttaaacaggt ataatactgc cattggttct ggggtaataa aactctcaga aggtgccaat
     3481 gccttgtcat ccaagtccgg agaattacta gatggtagcc atcaattatc agaaggtgct
     3541 actaaactag ctgatggtag ttctcaattg agtcagggtg gtcatcaatt aacgagcgga
     3601 ttgactgaat tatcaacagg attgtcaacc ttaaatggtt ccttagccaa agcctctcag
     3661 cagttatcgc ttgtttctgt gactgataaa aatactaaag ctgtcgcaaa acctcttgtg
     3721 ttaaatgaga aagacaaaga tggtgttaag acgaatggga tcgggatggc accttatatg
     3781 attgctgttt ctctaatggt tgtggccctt tcaaccaacg tcatttttgc taattcttta
     3841 tctggtcatc cggtcaaaga taaatgggat tgggctaaac aaaaatttgt tattaatggt
     3901 tttatttcga ctatgggatc cattgttctc tacttagcta ttcaattatt agggtttgaa
     3961 gcccgttatg gtatggaaac cttaggattt attatgctaa gtggttggac gtttatggct
     4021 cttgtcacag ctttggtcgg ttgggatgat cgatatggct cttttgcttc tttggtcatg
     4081 ttattgcttc aggttggctc ttcaggtggc tcttacccca ttgagttaag tggagcattc
     4141 ttccaaaagt tacatccttt cttaccaatg acttatgtgg tatctggttt acgacaaacc
     4201 atttcattat caggtcatat tggagtagaa gtgaaagtct taactggttt cttactggca
     4261 tttatggtat tagcactact catttatcgt cctaagaaaa cagtctaaat aaaataacct
     4321 caaaaaaaac agcatctaag gcagttacac tagatgctgt tttttgtctt attttgacaa
     4381 taacttgaca atttctgtca agttttttat tgtcttgtta agattatttg atagtaatgt
     4441 ctcccttatt gagattaacc gttaaatttc cagtagctgc tttattctca gccacataag
     4501 aaataacatc tgaagttgat tccttaccaa tcttagctgg tgtcagctgt gagccaaggg
     4561 agactttacc attttcggtc cttgctctgt aggcgatggc ctttgctttt gtcaaggtta
     4621 tgtcaacatc aatatcacca ccagtaatag tattagtccc tttaagggta agagcatgag
     4681 cagtgaatat agcaccatta tcattggttt cctcgttttc ttgctcacta gtaacagtga
     4741 aagtcacatt ttcaaggctt gtttcttcgg cttcaacccc accaggagat agagattgga
     4801 tggtgacaga tttaagatta gtattttttg tggttaattg tccatgccct aagctaatcg
     4861 tcccattttc taaactagaa ttcgtaaggc ttgacaacga atagtcggct ttcaactcaa
     4921 gattggctaa caagctatca gtagcgttaa atgttccaaa aaccttccct ttctttattc
     4981 tagtatttag aagtgtcaga ccaccactga actcaaggtc ttgaaccgtt aaatccgata
     5041 tagtggcttg aggcatgctt gagcctttga gctctttaag actggtacct tttggaagcg
     5101 ttatggtagt ggttcggtag ttgtggttgc ggtcactttt atttaatcca aacccgatca
     5161 gttcaatacc tccggtgatg atgacatctc tgggtttttc agaaatatga agtgtctcgt
     5221 tctctatttt aatttctaaa ggatcaataa atttagaatg tgtgtaatag gtaacggttg
     5281 gttttttgac aggccctgtt tctactgtaa tagttgaaaa attggtatca atatcaagag
     5341 ctgttacgtg atcaaatgtt tggataacct ttttaggggc tgtttggtgt ttaatgtctt
     5401 gaagcccgcc agttgcataa ccagctccta aaagaatggc tcctaaaaca atacacacga
     5461 cactggtcat aaaacatttg cgtgagatat ttttcatgct tgagctcctt tcttgtgact
     5521 aatccattta ataaaggcaa cgaaggcacg tcctgaaaaa cgcaggagtg cagtggcaat
     5581 aatccaaatg agaagaccac caccaaaaca caacaaggcg ctgccgattc ccatagcttg
     5641 tgcaggaata gatgagccaa tcaaggtcaa gctttcaaac agggtcactc ctgcgacaag
     5701 aatacctgca agcccaaaaa tgtaggcggc aaagatagct gtgagcccga gcattaggca
     5761 ggcaataata aagagaatca acgccagcaa tacgggtaaa gcaatcggag cagcaaagag
     5821 ggacaaaatg gttaatccaa taattgttgc ccgatttttg ggagttttct cgggagttgc
     5881 caagtgtttt cctagaacat ttgaaatgat ttcactggca gcttccttag gatttcctaa
     5941 atcgtcgata acctggcttt ctttgtcagg accagcttca tcaaaatatt caatataata
     6001 ttccaacgct tcatggtagt cttctctagg tagtttgcgc aagtatttat ctagttctgc
     6061 tagatactca gtccttgtca tgtcttaagc tcccttcaat aatcccgtct aaggcaaatt
     6121 tatagctctg ccattctttt tttagaaaaa tcagctgtgc tctccccgaa gaagtgacag
     6181 cataatattt acgctttcgt ccctgatgtt cttgactata agttgtcaaa aaacctgcct
     6241 tctccaattt tttaagaata ggatagaggg tggattcttt gatattagcc actagtttaa
     6301 tggtttgact aatatcgtaa ccgtaagaat cgtttttttc gacaatggct aaaatcagaa
     6361 attcaatcaa ggtagccgat actggaaaat acattttagg ctcctttcat atataaaaat
     6421 tttatatat
//
LOCUS       DAUGSW010000056         6331 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUGSW010000056 DAUGSW010000000
VERSION     DAUGSW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6331
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.056"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(123..196)
                     /locus_tag="VIB18_001503"
     tRNA            complement(123..196)
                     /locus_tag="VIB18_001503"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(160..162),aa:Asn,seq:gtt)
     gene            complement(230..301)
                     /locus_tag="VIB18_001504"
     tRNA            complement(230..301)
                     /locus_tag="VIB18_001504"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(266..268),aa:Glu,seq:ttc)
     gene            complement(497..1474)
                     /locus_tag="VIB18_001505"
     CDS             complement(497..1474)
                     /locus_tag="VIB18_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEQ8766500.1"
                     /translation="MSNINSTRKSSYSHLSATERGEIAAYLKMGKKPVEIARLLGRHC
                     STICREIKRGVDQVKDKNGKQTFFNAYFADSGQRVYETNRQKSSYLKLNGCSARFIAQ
                     LESALTANIRLHSVDSFVQTYKVNHPEEVVPSTKTIYRYIKEGLLAIKPIDLPKMVSI
                     RKRSKKVMKTNKKTLGKSIEERPEYINDRSEFGHWEIDLVLGKKTKGEAVMLTLIERQ
                     TRYALGVKLEDKQSQTVNRAVTHLISQYPIASITADNGSEFSLLSTLEAVDVYFAHPY
                     SSHERGTNENFNGLLREYVPKGISLNPLTSEELDNDITAINERLRRLLQ"
     gene            1639..1712
                     /locus_tag="VIB18_001506"
     tRNA            1639..1712
                     /locus_tag="VIB18_001506"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1673..1675,aa:Arg,seq:tct)
     gene            complement(1869..2348)
                     /gene="rlmH"
                     /locus_tag="VIB18_001507"
     CDS             complement(1869..2348)
                     /gene="rlmH"
                     /locus_tag="VIB18_001507"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEQ8766501.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            2560..3783
                     /locus_tag="VIB18_001508"
     CDS             2560..3783
                     /locus_tag="VIB18_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEQ8766502.1"
                     /translation="MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            3842..4648
                     /locus_tag="VIB18_001509"
     CDS             3842..4648
                     /locus_tag="VIB18_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEQ8766503.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KTIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            4882..6237
                     /gene="dnaA"
                     /locus_tag="VIB18_001510"
     CDS             4882..6237
                     /gene="dnaA"
                     /locus_tag="VIB18_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEQ8766504.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQAKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
BASE COUNT         2114 a         1112 c         1092 g         2013 t
ORIGIN      
        1 aatcctgtta gttcacaatg ctgtatttag tggtttaata attagtaaat tgagcatttg
       61 acctgagtat ctgttttact aaataaaaaa atcctaagat tatcttagga aatatcttat
      121 cactccggca gtaggactcg aacctacgac atcatgatta acagtcatgc gctactacca
      181 actgagctat gccggaaaaa gaaaaaaatt gccaaaatga caattgcgat agtccgtacg
      241 ggattcgaac ccgtgttacc gccgtgaaaa ggcggtgtct taaccccttg accaacggac
      301 cagaagtttt ggaggatatc tccttaacac tcttactatt atagcagatt gatttttttt
      361 gtctatactt tttttaaaaa aaatttgatt ttttttaaac cgcaaattgt caagtcaagt
      421 gcaacgagtt catagataac tagagttcca gaggttaagc tgttcgggat agctcaaaca
      481 ggaattttga ggattgctat tgaagaagtc gtcttaggcg ctcattgatg gcagtaatat
      541 cattgtcaag ttcttcagag gttagtggat taagtgagat tcctttaggg acatattctc
      601 tgaggaggcc attgaagttc tcgtttgttc ctctctcatg tgaagaatag ggatgtgcaa
      661 agtaaacgtc aacagcttct aaggttgaga gtaaactaaa ctcagaacca ttatctgctg
      721 tgatggatgc aataggatac tgactgatga gatgcgtgac agcgcggtta acggtttggg
      781 actgcttgtc ttctagctta actcctagtg catagcgtgt ctggcgctct atcaaagtca
      841 acataacagc ttcacctttg gttttcttgc cgagaaccaa atcaatctcc caatgcccaa
      901 attcagaacg atcattaata tattctggac gttcttcgat agatttacct aaagtcttct
      961 tattcgtttt catgactttc ttagaacgtt ttctgatact aaccatctta ggcaaatcga
     1021 ttggtttaat agctaacaac ccctctttga tataacgata aatcgttttg gtagagggga
     1081 cgacttcttc aggatggttc actttgtaag tctgaacaaa actatccaca ctatggagac
     1141 gaatgttagc cgtcaaggca gattctaatt gtgcaatgaa cctagcggag cagccattca
     1201 atttgaggta agaactcttt tgacgattgg tttcatagac acgttgtcca ctatcagcga
     1261 aataggcgtt gaagaaggtt tgttttccat tcttatcctt tacctgatct actccacgtt
     1321 ttatttctcg gcagattgta gaacagtgac gccccagaag tcgagcaatc tcaacgggtt
     1381 tctttcccat tttaagataa gcagcaattt caccgcgttc tgtggctgaa agatgagaat
     1441 aggatgactt tctggtagaa ttaatattag acatgttcat ctgctttcca tactgaattg
     1501 gggaattcta gtatatcaga cgaacatgtc ttttttgttg cacttcattt tacaacgcgg
     1561 gatataatgt tattttctag ttttttcaaa ataaatattg acagttttag ataatttttg
     1621 ttaaaatgat gtggttaagg tctcatagct cagctggata gagcattcgc cttctaagcg
     1681 aacggtcgca ggttcgaatc ctgctgggat caaagataaa aaagcactgt tttagtgctt
     1741 tttttgtatt taccttagtg tattgaaaag ataggattta gtacgtcttt ttttaatatt
     1801 tgcttttaat tataccgaac tattatctaa taaagtggta agagttagtt attccaattc
     1861 acactctctt acttatgata aggactgcct tgtgtaatca taaaagcacg ataaatttgc
     1921 tcagtaagga ctagacgcat taactgatga ggtaaggtta acaatccaaa actcattagc
     1981 atattagctc tttttttaat aattgaatct aatccaagac tcccaccaat aataaacgtg
     2041 atagttgaat atcccttaac agtaacccct gatattaatt cactaaatgt ctctgaagga
     2101 aactgttttc cttcaatagc taatgcaatt acaaaatcac gttccccaat ttttttatgg
     2161 attcgctgag cttctttact cataatcaat tgattatcag caaaacttgc tttatctggt
     2221 gttctttcat cagttaactc aatcatttcg aattgacaaa aacgggaaag tcttttttga
     2281 tattctgaaa taccatcttt gaggtatctt tcttttagtt ttccaacaca aattagtttt
     2341 actttcatag cttaattgta tcacaagaac attacttttt acacaattta tccacaagtt
     2401 atttttcttc aactactaat aaaaaccttt gtacaaaggt ctttattagt aaaaagaaaa
     2461 gtaatccaca gcctgtggat tacttttctt ttttttattt ttaaggtata attaagcaaa
     2521 gttctataag ctatggacaa ataattcgga ggacaaaaca tgccaagtat gaaacatatc
     2581 ttaaaatcct taagtatttt actaattgga tttttaggag gattaatagc aattattaca
     2641 ttcaataatc tctacccaca ttctccttca aaaataaatt caggtaaggc aacaactagt
     2701 aatatggttt ttaacaacac aaccaatact actaaagctg tcaaagctgt tcaaaatgca
     2761 gttgtatcag ttattaatta tcaagataac ccttcttcat ccctttctaa cccttataca
     2821 aaactctttg gagaagggcg ttcaaaagag aataaggatg ctgaattatc tatttttagt
     2881 gaaggatctg gggtcattta tcgaaaagat ggcaactccg cttacgttgt tactaataac
     2941 catgttatcg acggagctaa acggattgaa attcttatgg cagacggatc taaagttgtt
     3001 ggtgaattag ttggagctga tacttattcg gatttagctg ttgttaagat ctcttcagat
     3061 aagataaaaa cagtagctga atttgcagac tctacaaaac taaatgttgg agaagttgct
     3121 attgctatcg gcagcccact aggaacacaa tacgctaatt ctgttactca aggaatcgtc
     3181 tctagtttaa gtcgtactgt aactttaaaa aacgagaatg gtgagactgt ctcaacaaat
     3241 gctattcaga cagatgctgc tattaaccct ggaaactctg gtggaccact aattaatatt
     3301 gaggggcaag taatcggaat taattcaagt aaaatttctt ctaccccaac tggtagcaac
     3361 ggtaatagtg gtgctgttga aggaattggt tttgctatcc catctactga cgttattaaa
     3421 attattaaac aactagaaac taatggtgaa gttatcagac ctgctcttgg aatatccatg
     3481 gtcaatttaa atgacttatc cacaaatgct cttagccaaa ttaatattcc aactagtgta
     3541 actggtggta ttgtagtagc agaagttaag gaaggaatgc cggcatctgg caaacttgct
     3601 cagtacgatg tgattacaga aattgatggc aaaacagtta attcaattag tgatttacaa
     3661 agtagtctat acggacacga tattaatgat actattaaag taacttttta tagaggaact
     3721 acaaagaaaa aagcagatat caaattaaca aaaactactc aagatttgac taaaacgcag
     3781 taaacaagct acctaaatac tattacattt tatcacataa aacagtccaa aggactgttt
     3841 tatgtttctt attctatcca ggaactccct tatgacaaaa gaattattga tagacctacc
     3901 aattgaagat attgttacaa atccctatca gccaaggata caatttaatc aaagagaact
     3961 ccaagaccta gcaacttcta ttaaatcaaa cggcctcatt caacctatta ttgttcgaaa
     4021 atctgacatt tttggctatg agttagttgc tggagaacga cgacttaaag cttcaaaaat
     4081 ggctggtcta aaaaaagttc cagctatcat caagaagatc tctacactcg agagcatgca
     4141 acaagctata gttgaaaatt tacaacgttc taaccttaac gctatcgaag aagctaaagc
     4201 ctatcagtta ttggttgaaa aaaaacacat gactcacgat gagattgcta aatatatggg
     4261 aaaatcaaga ccttatatta gcaacacctt acgtctgtta caactcccag cacctatcat
     4321 taaaacaatt gaagaaggaa aaattagtgc gggacacgcg cgtgctcttt taactttgag
     4381 tgatgataag caacaactgt acctcactca taaaatacaa aatgaaggcc taagtgttag
     4441 gcaaattgag caactggtta cttctactcc aagttcgaag ctatctaaaa aaactaaaaa
     4501 tatttttgct acttctttag agaaacaatt ggctaaatca ttgggactct ctgtcaatat
     4561 gaagctgaca gcaaaccata gtgggtacct tcagatatct ttttccaatg atgatgaatt
     4621 aaacagaatt atcaacaagc taaagtagct tgttgataat tctgtttttt cttttttagt
     4681 tttccacatg aaaaatagtt gaaaacaata gcggtgtcac cttaaaatgg cttttccaca
     4741 ggttgtggag aacccaaatt aacattgtta atttattttc cacaggttgt ggaaaaacta
     4801 actattatct atcgttctgt ggaaaactag aatagtttat ggtagaatag ttctagaatt
     4861 atccacaaga aggaacctag tatgactgaa aatgaacaaa ttttttggaa cagggtcttg
     4921 gaattagctc agagtcaatt aaaacaggca acttatgaat tttttgttca tgatgcccgt
     4981 ctattaaagg tcgataagca tattgcaact atttacttag atcaaatgaa agaactcttt
     5041 tgggaaaaaa atcttaaaga tgttattctt actgctggtt ttgaagttta taacgctcaa
     5101 atttctgttg actatgtttt cgaagaagac ctaatgattg agcaaaatca ggccaaaatc
     5161 aaccaaaaac ctaagcagca agccttaaat tctttgccta ctgttacttc agatttaaac
     5221 tcgaaatata gttttgaaaa ctttattcaa ggagatgaaa atcgttgggc tgttgctgct
     5281 tcaatagcag tagctaatac tcctggaact acctataatc ctttgtttat ttggggtggc
     5341 cctgggcttg gaaaaaccca tttattaaat gctattggta attctgtact attagaaaat
     5401 ccaaatgctc gaattaaata tatcacagct gaaaacttta ttaatgagtt tgttatccat
     5461 attcgccttg ataccatgga tgaattgaaa gaaaaatttc gtaatttaga tttactcctt
     5521 attgatgata tccaatcttt agctaaaaaa acgctctctg gaacacaaga agagttcttt
     5581 aatactttta atgcacttca taataataac aaacaaattg tcctaacaag cgaccgtaca
     5641 ccagatcatc tcaatgattt agaagatcga ttagttactc gttttaaatg gggattaaca
     5701 gtcaatatca cacctcctga ttttgaaaca cgagtggcta ttttgacaaa taaaattcaa
     5761 gaatataact ttatttttcc tcaagatacc attgagtatt tggctggtca atttgattct
     5821 aatgtcagag atttagaagg tgccttaaaa gatattagtc tggttgctaa tttcaaacaa
     5881 attgacacga ttactgttga cattgctgcc gaagctattc gcgccagaaa gcaagatgga
     5941 cctaaaatga cagttattcc catcgaagaa attcaagcgc aagttggaaa attttacggt
     6001 gttaccgtca aagaaattaa agctactaaa cgaacacaaa atattgtttt agcaagacaa
     6061 gtagctatgt ttttagcacg tgaaatgaca gataacagtc ttcctaaaat tggaaaagaa
     6121 tttggtggca gagaccattc aacagtactc catgcctata ataaaatcaa aaacatgatc
     6181 agccaggacg aaagccttag gatcgaaatt gaaaccataa aaaacaaaat taaataacat
     6241 gtggaaaaga atatctttta tgaaatagtt atccacaagt tgtgaacaac catttaatct
     6301 tggattctct cgtttattta gagttatcca c
//
LOCUS       DAUGSW010000057         5949 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUGSW010000057 DAUGSW010000000
VERSION     DAUGSW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5949
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.057"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            52..249
                     /locus_tag="VIB18_001511"
     CDS             52..249
                     /locus_tag="VIB18_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8766505.1"
                     /translation="MKNNLRVILARQRKKISDVHEATGVSKTTLTALYYERTENPDSK
                     TLLKIAKCLNVTLDELLTVED"
     gene            263..871
                     /locus_tag="VIB18_001512"
     CDS             263..871
                     /locus_tag="VIB18_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEQ8766506.1"
                     /translation="MRTETWNGYTIRFVENNGEWWAVLADIAKALDLKPKFIKQRLGD
                     EVVSNNHVADSLGRQQEMLIVNEFGIYETIFSSRKKEAKTFKLWVFEIIKQLRQSTGL
                     EGFQVFRMLDKEHQKQAMNRLVNGLEQIKQTDLIKANTIANKAVSNKYGLPKMISKSQ
                     MTEQMLKDREQLLDDTVELMVIKDKFDLGVSVSNAIYSRATH"
     gene            892..1299
                     /locus_tag="VIB18_001513"
     CDS             892..1299
                     /locus_tag="VIB18_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766507.1"
                     /translation="MARTPFTQELLHQIFDDTGTMSLELIAERLPDWSEKDIKLRLAA
                     WRYRNNIDYTMANGEIDIFEIINNRKAISEEVSAGRQLKLEEYFKQVQATAEIINKPT
                     ASDTNRLKAIQLQQVAMDEIPDQYFKELTELYG"
     gene            1312..1941
                     /locus_tag="VIB18_001514"
     CDS             1312..1941
                     /locus_tag="VIB18_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEQ8766508.1"
                     /translation="MNLVYMDGKKEPYTTHDIITEHAEIDIISVRKLIDKHKKDLEAF
                     WVLSFEIHKPEKGSLGGRPRRIYHLNEQQATLLVTYLGNTEPVREFKKNLVKAFFEMR
                     EELTQIRLQRSLEAPKQKTLNEAIKTWEHAPKMAYPTVYNLLLKAVTGKNSKQLKATR
                     GGYSGTDCLNSIELAQYTALEDMAIALINLNFTYQDIKTMALKNTLQCA"
     gene            2186..2518
                     /locus_tag="VIB18_001515"
     CDS             2186..2518
                     /locus_tag="VIB18_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766509.1"
                     /translation="MKYRVETNPFSKDRYTPEQLEMFKNRLLSKNKAEAYFTRLYNQH
                     IAWVIIANVMTEYVIKFRKSATSFEEAWDALDYQRTTEIVFRAVNGLPCSEKDSGELE
                     TYLSEVSA"
     gene            2518..2709
                     /locus_tag="VIB18_001516"
     CDS             2518..2709
                     /locus_tag="VIB18_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766510.1"
                     /translation="MQELNLTPTQTLILFFVLGLLGLLLSRSKPLIEIDLSEDTQVPK
                     PRQNANYGAYIQSQNHYYN"
     gene            2721..3050
                     /locus_tag="VIB18_001517"
     CDS             2721..3050
                     /locus_tag="VIB18_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766511.1"
                     /translation="MTLPENYRCVLNLIKVGADNPITGAEISLILKLEERSVQSIISS
                     LITRYNVPIIGIRHGFNRGYFIPANKEELLDGAKAFYNQVQKEQERLSVLLNADLTSY
                     KELLKGG"
     gene            3053..3325
                     /locus_tag="VIB18_001518"
     CDS             3053..3325
                     /locus_tag="VIB18_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766512.1"
                     /translation="MNVFSQDYEAKLLEQNLTAFNRFLEAYQKPKPRVLGLITAEQVK
                     EELNIKGKTLKRWENAGLRRYQPPLEDTRKHYYKVSDILIFLGVNV"
     gene            3326..4183
                     /locus_tag="VIB18_001519"
     CDS             3326..4183
                     /locus_tag="VIB18_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEQ8766513.1"
                     /translation="MAIYEARGFSSYLYPYKGPLEPFDYIAQFRPLKPPEDIDIEEYK
                     RTQAPYCLSGKVTAEKNGSYKRNNASLVYRDLIFLDYDEIETGVNLPKIVSQTLREYS
                     YIIYPTIKHTPEKPRYRLVMKPSDVMTEATYKQVVKKIADKIGLPFDLASLTWSQLQG
                     LPVTTGDPEDYQRSVNRGLDYPVPKNGSTPNRQVVTTYTPRPRSQRSITMRVIDTLFN
                     GFGDEGGRNVALTKFVGLLFNKWVDCDLETAYELVQIANSVTTKPLPIDEIDRTFTSI
                     AKAEYRKRR"
     gene            4152..5840
                     /locus_tag="VIB18_001520"
     CDS             4152..5840
                     /locus_tag="VIB18_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8766514.1"
                     /translation="MLKQNTEREGRTIEQEDLKNLENEITEARENEDKYFSTFKGVRG
                     QLIKECQEMKDEAFKIAYDGVMADSKHLENVKAGRLTKVQHEELAKEKGQEASEKALP
                     KTPLGVAIMLKHYLCFIRVKPEAQGQKAPLYFFHPDHGVWLEDNEFLQDLISVIFPNA
                     TEKQAFDTLYKIARQSQLKEIQREYTVIGNQLYNYKTGQFEELTPDITVTRKIKTGYN
                     KKAKEPTIKGWKPTAWLLELFDGDAELYNLAIQIIKASITGQSLQKIFWLFGEGGTGK
                     GTFQQLLINLVGMDNVASLKITELAKSRFTTSILLGKSIVIGDDIQKDAVIKDTSDIF
                     SLATGDIMTIEDKGKRPYSIRLNMTVVQSSNGLPRMNGDKSAIDRRFRILPFTKVFKG
                     KPNKAIRNDYINRKEVLEYLLKLAIETPITDINPKASIEILEEHHKEMNPVIDFVSKF
                     FTDELTSEFIPNSFVYHVWKGFLEYYDIKQIKSERGLHKEIKSNLPEGFEAGQKVIPV
                     GRQLHTGFYPKEDLPLFASASYANGRASPEKQKKPKNERGYYNHWPTHKKQKKT"
BASE COUNT         2123 a         1099 c         1174 g         1553 t
ORIGIN      
        1 gttagtgata acactaaaat atatcaaata tcaaaaaagg aggttgatat tttgaaaaat
       61 aatctaagag ttattttagc aaggcaacgt aaaaagattt cagacgtcca cgaagctaca
      121 ggggtttcta aaactacttt aaccgcactt tactatgaga gaacagaaaa ccctgatagt
      181 aaaacattgc taaaaattgc caagtgtcta aatgttacac ttgatgaact attgaccgtt
      241 gaggactaga aaggacacct tattgagaac agaaacatgg aacggatata ctattcgatt
      301 tgtagagaat aacggcgaat ggtgggcggt gctagctgat attgctaaag cactagatct
      361 gaagccaaaa tttattaaac aacgtttggg agatgaggtt gtttcaaaca accacgtcgc
      421 agacagttta gggcgtcaac aagaaatgtt aatcgttaat gagtttggca tttatgaaac
      481 tatcttctca agtcgtaaga aggaagccaa aacctttaaa ttatgggtat ttgagattat
      541 caaacaacta cgccaaagca caggcctaga gggcttccaa gtgtttagaa tgttagataa
      601 agaacatcag aagcaggcaa tgaatagact ggttaatggc ttagaacaga ttaaacagac
      661 tgaccttatc aaagccaaca cgattgccaa taaagcggta tctaataagt atggattacc
      721 aaagatgatt agcaaatctc aaatgactga acaaatgtta aaagatagag agcagttatt
      781 agacgatacc gttgaactta tggtaatcaa ggataaattt gaccttggtg tcagtgtttc
      841 aaacgctatt tacagtagag caacccatta agaaaggcag gtaaataaca aatggctaga
      901 acaccattta cacaagaatt attacatcag atatttgacg atacaggaac aatgagccta
      961 gagctgattg ctgagcggct tcccgattgg tctgaaaaag acatcaagct taggctggca
     1021 gcttggcggt atcgaaataa cattgattac accatggcaa acggtgaaat tgatatcttt
     1081 gaaattatca ataacagaaa agccatatcc gaagaagttt ccgcaggaag gcaacttaag
     1141 cttgaagagt atttcaagca agtacaggca acggctgaaa ttattaataa accgactgct
     1201 agcgacacca atcgtttaaa ggccattcaa ttacaacaag tggctatgga tgaaattcct
     1261 gatcagtatt ttaaagaact aacggaactc tatggataaa ggaggattac catgaaccta
     1321 gtttacatgg acggtaagaa agagccgtac accacacacg acatcataac tgagcatgct
     1381 gaaattgaca ttatttcagt tagaaagctg attgataagc ataaaaagga tttagaagcg
     1441 ttttgggttt tgtcatttga aatccataaa cctgaaaaag gttcactagg cggacgacct
     1501 agaagaattt atcacttaaa cgaacagcag gcgactttat tagttaccta tctaggaaat
     1561 accgaaccag tcagagagtt taaaaagaac ctagtcaagg cattctttga aatgcgagaa
     1621 gaactcactc aaattaggtt acagcgttct cttgaagctc ctaaacaaaa aacacttaat
     1681 gaagctatca agacatggga acacgcgcct aaaatggctt atccgactgt gtacaatcta
     1741 ttgcttaaag ctgttactgg taagaatagc aagcaattaa aagcaaccag aggtggttat
     1801 tctggtactg actgcttaaa ctcaattgag ctagcacagt acaccgcttt agaagatatg
     1861 gcaatcgctc ttatcaatct taattttacc tatcaagata ttaagacaat ggcattaaaa
     1921 aacacgctac aatgcgcgtg aaaacaacaa aaaaggcttt gacagcgacc aaacttccaa
     1981 gccttcaact agtataacta aactcaatta ataaagcagg caagctatta ttaaaagggt
     2041 tttatatctt atattatagc atattgaagc tattttgacc atacgtaggg agctatccct
     2101 taaaactagc atgaatctag tataagaaac aagcaatcaa taaaaacact acacagaaaa
     2161 taataattaa gcgagaaaaa acataatgaa atatagagta gaaacaaatc ctttttcaaa
     2221 agatagatac actcctgaac agctagaaat gttcaaaaat cgcctactca gcaaaaataa
     2281 agcagaagcc tatttcactc gactatataa ccaacatatc gcttgggtaa ttattgctaa
     2341 cgttatgaca gagtacgtca ttaaattcag aaaaagtgcc accagctttg aagaagcatg
     2401 ggacgcttta gactatcaac gaaccacaga gattgtcttt agagccgtta acggtttacc
     2461 ttgttcagag aaagactcag gggaactaga aacttattta agtgaggtat cggcatgatg
     2521 caagaactta acctcacacc aacacagacg cttattctat tctttgtttt aggtctctta
     2581 gggcttcttc ttagccgttc taagccatta atagagattg acttatcaga agatacccaa
     2641 gtccctaaac cacgtcagaa cgcaaactat ggggcttata ttcaatcaca gaaccattat
     2701 tacaattagg gaggaactga atgacactac cagagaatta tagatgtgtc cttaatctga
     2761 ttaaggtggg ggcagacaac cccattacag gggcagagat tagcttaata ctgaaacttg
     2821 aagagcgttc cgtccaaagt atcatcagta gcttaatcac acgctataac gtccctatta
     2881 tcggcattag acacggattc aatcgtgggt actttatccc agctaacaaa gaagaattac
     2941 tagatggtgc taaagccttt tataatcaag tacaaaagga acaggaacgc ctaagtgtgt
     3001 tattgaatgc cgatttaacc agttataagg aattactcaa aggaggttag gcatgaacgt
     3061 atttagtcaa gattatgaag ccaaactctt agaacaaaac ctgaccgctt ttaatcgctt
     3121 tttggaagcc taccagaaac ctaaaccaag agttttaggg ttgatcacgg ccgaacaagt
     3181 caaagaggaa ttaaatatca aaggtaaaac cctaaaacgg tgggaaaatg ctgggttaag
     3241 acgataccaa ccaccactag aagacaccag gaaacattat tacaaggtca gtgatattct
     3301 tatctttttg ggggtaaatg tgtagatggc tatttatgaa gcaagaggct ttagctctta
     3361 tttgtacccc tacaaaggac ctttagaacc atttgactat attgctcagt ttagaccttt
     3421 gaaaccgcct gaggatattg atattgaaga atacaagcga acacaagccc cctactgcct
     3481 gagtggcaag gtcacagcag agaaaaacgg tagctataag cgcaataatg ctagtttagt
     3541 ttatcgcgat ttgatttttc ttgactatga cgagatagaa acaggcgtca acctacctaa
     3601 aatcgtttct cagacgcttc gggagtatag ttatattatt tatccaacga ttaaacacac
     3661 ccctgagaag ccccgttatc gccttgtcat gaagcctagt gacgtgatga ctgaagcaac
     3721 ttataaacaa gtggtcaaga agatagccga taagattgga ctgccgtttg atttagctag
     3781 ccttacctgg tcacaattac aaggcttacc tgttacaaca ggcgacccag aggactatca
     3841 gcgctctgtg aaccgtggtc ttgattatcc tgttcctaaa aatggtagca cgccaaacag
     3901 acaagttgtt actacttaca cgccacgccc tagaagtcag cgttctatta ccatgagggt
     3961 catagatacc ttgtttaatg gttttggaga cgaaggcggg cgcaacgtgg ccttaactaa
     4021 gtttgttggc ttgctattta ataaatgggt ggattgtgat ttagagacgg cttatgagct
     4081 ggtacaaata gctaacagcg tgacaactaa gccactaccc attgatgaga tagataggac
     4141 gtttaccagc attgctaaag cagaatacag aaagagaagg tagaaccata gagcaagaag
     4201 atttgaaaaa cttagaaaat gaaatcactg aagcgcgtga gaatgaagat aaatatttca
     4261 gcactttcaa aggtgttaga ggtcagctta tcaaggaatg tcaagagatg aaagatgaag
     4321 ctttcaagat tgcctatgat ggcgttatgg ctgatagcaa acaccttgag aacgtaaaag
     4381 cgggtagatt gaccaaggta caacatgaag aattagctaa agaaaaagga caagaagcca
     4441 gtgaaaaagc tttacctaaa acacctttgg gcgtggctat tatgctcaaa cactatctct
     4501 gctttattcg agttaaacct gaagctcaag gacaaaaagc cccactttac ttttttcatc
     4561 ctgatcacgg ggtttggcta gaagataatg agtttttaca agatctcatt tcagttattt
     4621 tcccaaacgc gactgaaaaa caagcttttg acacacttta caaaattgct aggcaaagtc
     4681 aactgaagga gattcaaaga gaatatacag ttatcggaaa tcagctctac aattataaaa
     4741 ctggtcaatt tgaagaatta actccagata taaccgtcac tcgcaaaatt aagacgggtt
     4801 acaataagaa agctaaagaa cccacaataa agggctggaa acctactgct tggctcttag
     4861 aattgtttga cggtgacgcc gaactttata accttgctat tcagattatt aaagctagca
     4921 tcacaggtca atccttacag aaaatcttct ggttattcgg tgaaggtggg acaggaaaag
     4981 ggacttttca gcaattactc attaatttag tgggtatgga taacgtggca agccttaaaa
     5041 taacagaact agcaaaaagc cgctttacta catctatact tctagggaaa tccattgtaa
     5101 ttggtgatga tattcaaaaa gacgcggtta tcaaagatac gtctgatata tttagtttag
     5161 ccacgggtga cattatgacg attgaggaca aggggaaacg cccgtatagt atccgtttaa
     5221 acatgactgt ggtacaatct tccaacggtt taccacgaat gaacggtgat aagtccgcca
     5281 ttgatagacg ctttaggatt ttacctttta ccaaagtatt taaaggaaag cccaacaaag
     5341 ctatcagaaa tgattatatt aatcgcaaag aagttcttga gtacttactt aagctagcga
     5401 ttgaaacacc aatcactgac attaatccaa aagcatctat tgagatactg gaagaacacc
     5461 ataaagagat gaacccagtt attgatttcg tttctaagtt cttcacggat gagctcacca
     5521 gcgaatttat tcctaatagc tttgtctatc atgtttggaa aggcttttta gaatactatg
     5581 acatcaaaca aataaaatca gaaagagggt tacataaaga aatcaaaagc aatcttcctg
     5641 aaggttttga agcaggccag aaggtcatac cagtaggccg acagctccat acaggttttt
     5701 atcctaaaga agatctacct ctgtttgcta gcgcatctta cgctaacggt agagcatcac
     5761 ccgaaaaaca gaaaaagcca aagaatgaac gtggatatta caatcattgg ccgacgcaca
     5821 aaaagcaaaa gaaaacttag ccattttata cgttttagca tttaaaaaat taaacgtata
     5881 aagaaatagc ccagtcatat caaggggttt atacgtttat cacgtttaac acgttatttt
     5941 aaaaatttc
//
LOCUS       DAUGSW010000058         5706 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUGSW010000058 DAUGSW010000000
VERSION     DAUGSW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5706
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.058"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            74..1363
                     /locus_tag="VIB18_001521"
     CDS             74..1363
                     /locus_tag="VIB18_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8766515.1"
                     /translation="MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTV
                     GFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQ
                     TSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
                     LQNLFPKTSLANDIAGSKESIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLA
                     IQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLT
                     YRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHHFQFVLISLDTPEPIAM
                     SNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKET
                     YFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            1413..2438
                     /locus_tag="VIB18_001522"
     CDS             1413..2438
                     /locus_tag="VIB18_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8766516.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGDGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     DVSRMRRNSTDSRSKTSLFPIVILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2452..2994
                     /gene="pgsA"
                     /locus_tag="VIB18_001523"
     CDS             2452..2994
                     /gene="pgsA"
                     /locus_tag="VIB18_001523"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEQ8766517.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2996..3835
                     /locus_tag="VIB18_001524"
     CDS             2996..3835
                     /locus_tag="VIB18_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8766518.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPIDYGYLTEKELENQLCQLI
                     SKM"
     gene            3811..4653
                     /locus_tag="VIB18_001525"
     CDS             3811..4653
                     /locus_tag="VIB18_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8766519.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDNQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELKEV
                     LKHG"
     gene            4646..5446
                     /locus_tag="VIB18_001526"
     CDS             4646..5446
                     /locus_tag="VIB18_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8766520.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSF"
BASE COUNT         1868 a          900 c         1052 g         1886 t
ORIGIN      
        1 aataaagcag atatcattaa agtagctaat cttttaaagc ttcaaactgt ctatttttta
       61 gaaggaatat aaaatgacaa aattagtaaa gataaactat cctaatattg acgaagacct
      121 ttactatgta aaattagaaa atggtttaac tgtttatttt ataaaaaaaa tagggttttt
      181 agaaaaaaca gctatgttga cagtaggttt cggttctctt gacaataagt tgacagtcga
      241 tgacgaatca cgagatgctc cagcaggtat tgcacacttt ttagaacata aactctttga
      301 agatgaatca ggtggagata tttcattaaa gtttacacag ctaggagcag agacaaatgc
      361 ctttacaact ttcaaccaaa cgagtttctt cttttcaaca gctagtaaat ttcaggaaaa
      421 tttggaactc cttcaatatt ttgttctttc tgctaatata acagatgaat ctgttagtag
      481 agaaaaaaaa ataatcgggc aagaaattga tatgtatcaa gatgatgctg actaccgtgc
      541 atatagtgga atccttcaga acttatttcc aaaaacaagt ttagctaatg atattgctgg
      601 ctcaaaagaa tccattcaaa agatcacgaa aatattattg gaaacgcatc atacttattt
      661 ttaccaacct actaatatga gtctattcat tgtcggtgat attgatattg acgaaacttt
      721 tttagctatt caaaggtttc aaaccacatt atcctatcca gatagaaaaa gggtaactgt
      781 tgatccttta cactactatc ctgtcattaa atcatcttct gttgacatgg atgttactac
      841 tgccaagctg gttgttggtt ttcgagggta tctgacctta actcagcatt cactattaac
      901 gtatcgtatt gccttgaagc tatttttatc aatgcttata ggttggactt ctaaaatcta
      961 tcatacgcta tatgaagatg gtaaaataga cgattcattt gatgtggatg ttgaaattca
     1021 tcatcatttt caatttgtat taatatcact tgatacacca gagcctatcg caatgtctaa
     1081 ctatatccgt caaaaattag ccactataaa gatatcaaaa gagtttacaa atgagcactt
     1141 aaatctatta aaaaaagaaa tgtatggtga ctttattcag agtttagact ctatagaaca
     1201 tttaacccat cagttcagtc tatacctgtc tgattctgat aaagaaacat attttgatat
     1261 tccaaaaatt atagaaagac tcactctaaa agatgttgtt acaattggaa aagcattttt
     1321 tgaaaaagct gatgcttcag acttcacagt cttcccaaaa tagatgaaaa tctgttataa
     1381 tagggttact atattatttt tgaggtacct gtatgagtga aaaaagtctt ggtgaagtgt
     1441 taagagaatc gcgtgttgga aaaaatatca cactagatga tatagaattg aagacaggga
     1501 tttcttccca ttatttgctg gcaatggaat tggatcagtt taaaattatt ccggaagaaa
     1561 aatttgatca atttttaaaa gaatatgctg acattgttga gttagatttc aatactttaa
     1621 aaagacgata ccgttatcaa gttaattcca aaaaagacag tgatataaaa tctgtaactg
     1681 agattgttga agagaagtta agtaagaaac gattacaaga gaagttgtta tcacatcaga
     1741 gcatggggga tggtcaaccg ttagaagttt ctaaaaacaa agaaacctta gttatccctg
     1801 taaagactgt tggtttagat agcaaatcgc cactaaaaac gatatcgcct gttagccaat
     1861 ttaaatcaga taacaggtta attcctaaaa aagatgtgtc acgtatgagg cgaaatagca
     1921 ctgacagtcg ttctaaaacg tcactatttc ccatagttat attaggaacg attgcttttg
     1981 caattatcag tgttatcatt ttaggtgttt ggcaacaatt cgaaaagagt caaagagcta
     2041 aagaagctga agttgctttg cttaaagctt ctgagcagtc tactaacggt ttaaaaaata
     2101 attcaaatga tcgcaaaact caagtcacaa ctgaggggtc gggtaattat ttaatagcga
     2161 ctgttactaa atctaaagag accgttgata ttagtgtgtc tttaaccgag gcacaaagta
     2221 gttggatttc tctaacaaat tcagaaattg gtgaaggtgg tataacattg actcaagact
     2281 cgccaactta tacagcgact ttacctgcag aaataacaga atcattgttg acacttggtg
     2341 tgacaaaagg tgtatctgta acaattgatg gacaacctgt tgatctatca cctttaacaa
     2401 gtactgactt aagttatatc acgtttaaga tccaataatt aaggtagact aatgataaaa
     2461 aaagaaaata ttcctaatct attaactctt gttcgaatcg caatgattcc tttctttctt
     2521 tttattactt cctcatctaa taaggtgggg tggcatattt ttgcagctgt gatttttgca
     2581 attgccagtt ttaccgatta tctagatggg tatcttgcgc gtaagtggca tgtagccagt
     2641 aattttggaa agtttgccga tcctctagca gataagatgc ttgtcatgag tgcctttatc
     2701 atgttagttg gacttggctt agttcctgcg tgggtgtcag ctgttattat ttgccgagaa
     2761 ttggcagtaa ctggtcttcg attactactt gttgaaaccg ggggaaaggt ccttgcagct
     2821 gctatgccgg gaaaaatcaa aacagcgaca caaatgttgt ctattatttt attactttgc
     2881 cattggatat tcctaggaaa cgtcttactc tatattgctc tttttttcac tatttattct
     2941 ggatatgatt attttaaagg agcaagcttt ctttttaagg atacgtttaa ataacatgtc
     3001 agctattatt gaacttaaaa aagttacatt taattaccat aaagaccaag aaaaaccaac
     3061 attagatggc gtatcgtttc atgtgaaaca aggtgagtgg ctgtctatca ttggccataa
     3121 cggatctggt aaatcaacga ctattcggtt aattgatgga ttattggaac cagaatcagg
     3181 gtctattatt gttgatggag atctactaac cataactaat gtttgggaaa ttcgtcataa
     3241 aattggtatg gtctttcaaa accctgataa tcagtttgtt ggagcaactg ttgaagatga
     3301 tgttgctttt gggcttgaaa ataaaggtat tgcacatgaa gatataaaag agagggttaa
     3361 tcatgcttta gagttagtcg gcatgcagaa ctttaaagaa aaagaaccag cccgtttatc
     3421 tggtggccaa aaacagcgcg tagctattgc aggtgcagtt gctatgaagc ctaaaattat
     3481 tattttagat gaagctacta gtatgcttga ccctaaagga cgattagagt taattaaaac
     3541 tataaaaaac atccgtgacg actaccagct gactgttatt tccattactc atgacttaga
     3601 tgaagttgct cttagtgata gagttttagt gatgaaagat ggtcaagtgg aatcaacatc
     3661 aacaccagaa caattatttg caagagggga tgaactactc caattaggtc ttgatatccc
     3721 ttttacaaca tctgttgtac agatgcttca agaagaaggt tatcctattg actatggata
     3781 tctcacagaa aaggaattag aaaatcagtt atgtcaatta atctccaaaa tgtaagttat
     3841 acttatcaag cagggactcc ttttgaaggg cgtgcccttt ttaacattaa tttagatatt
     3901 ttagatggtt cttatacggc ttttatcgga catactggat ccgggaaatc gaccattatg
     3961 caattgctaa atggtttaca cgttccgaca acgggaattg tcagcgtaga taaccaagat
     4021 ataacgaatc actctaaaaa taaagagatt aaatctattc gaaaacatgt aggattagtt
     4081 tttcaatttc cagaaagtca actatttgaa gagacagttt tgaaagatgt tgcttttggc
     4141 cctcaaaatt ttggggtctc tccggaggaa gcagaagctt tagcgcgtga aaaactagct
     4201 cttgttggga tttcagaaaa tctttttgaa aagaatccat ttgaactctc agggggtcaa
     4261 atgcgtcgtg ttgctattgc gggtatcctt gctatgcagc caaaggtttt agttttagat
     4321 gaaccgactg ctggtcttga tcctaaaggg cgtaaagaat taatgactat ttttaaaaag
     4381 ttacaccaat ctggcatgac tattgtttta gtaacccatc tgatggatga tgtggccaat
     4441 tacgcagatt ttgtatatgt tcttgacaaa ggtaaaatta ttttatcagg aaaacccaaa
     4501 acaatttttc aacaagtcag tttgcttgag aaaaaacagt taggagttcc taaggtgact
     4561 aaacttgctc aaaggcttgt tgatagagga atacctatct cttctttgcc tattacctta
     4621 gaggagctaa aagaggtact aaaacatgga taagctgatt cttggtcgtt atattcccgg
     4681 agattctctc attcatcgtc ttgacccaag aagtaaatta ttagcgatga ttatttatat
     4741 tgtcattatc ttttgggcta acaatgttgt gacaaatttg ttgatgttga cttttacttt
     4801 agcagttgtt tttttgtcaa aaatcaagtt gtctttcttt ttaaatgggg ttaaaccaat
     4861 gattggtatt atcctcttca cgactttatt tcagatgttt ttctcacaag gaggaaaagt
     4921 aatttttagt tggtggttca ttagcataac tgatttagga ttgagccaag ctattttaat
     4981 ttttatgcgt ttcgttctaa ttattttctt ttcaacgctg ttaacgttga cgacaacacc
     5041 tttaagccta tctgatgcag ttgaatcatt attaaaacct ttaacaagat ttaaagttcc
     5101 agctcacgag atcggactaa tgctttcttt aagtttacgt tttgtgccta ctttaatgga
     5161 tgataccacg cgtattatga atgcacaaag ggcccgtgga gttgattttg gagagggaaa
     5221 tttaattcaa aaagttaaat ccattattcc tattttaatc cctcttttcg cttcaagctt
     5281 taaaagagcc gatgcattag ctattgctat ggaagctaga ggttatcagg gaggagaagg
     5341 gcgaactaaa tatcgtcaat tagactggca gctaaaagat agtttagcta ttggaatagt
     5401 ttctttattg ggtttgctac tttttttctt gaaaacctct ttttaatatt ttttagcaca
     5461 aaacttttct ttattataag aagtgaattg tacctcaaaa gttagataca acatctaatg
     5521 attgaggtac ttttcttcat ttgaggaatt gaaaaccgct atctcaacta tattaatcct
     5581 cccaacaata acaaatcgaa cgaaatctaa aaggactgag tcctgttcaa tacagaacta
     5641 aattcttagt ttaatgatat tatcccgctt tttaatgttg ctaagaagaa gagttttatg
     5701 attttt
//
LOCUS       DAUGSW010000059         5525 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUGSW010000059 DAUGSW010000000
VERSION     DAUGSW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.059"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            152..709
                     /gene="lepB"
                     /locus_tag="VIB18_001527"
     CDS             152..709
                     /gene="lepB"
                     /locus_tag="VIB18_001527"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8766521.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            885..2699
                     /gene="glmS"
                     /locus_tag="VIB18_001528"
     CDS             885..2699
                     /gene="glmS"
                     /locus_tag="VIB18_001528"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEQ8766522.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQLAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            2895..3230
                     /locus_tag="VIB18_001529"
     CDS             2895..3230
                     /locus_tag="VIB18_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEQ8766523.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            3336..3977
                     /locus_tag="VIB18_001530"
     CDS             3336..3977
                     /locus_tag="VIB18_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8766524.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            3987..4616
                     /locus_tag="VIB18_001531"
     CDS             3987..4616
                     /locus_tag="VIB18_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766525.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLLGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            4632..5468
                     /locus_tag="VIB18_001532"
     CDS             4632..5468
                     /locus_tag="VIB18_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8766526.1"
                     /translation="MIIKKRTIAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         1723 a          885 c         1155 g         1762 t
ORIGIN      
        1 tcatgttaat tcactagtgt taatttactt taatgagtct aagtttgtat tttatacaga
       61 atgagaaacg tttattggta ttgatcaaaa attgtttact ttttttctag cttagaacat
      121 ggtataataa gacaatagac taggagttaa tatggtaaag cgagatttta taagaaatat
      181 attattgtta ttaattgtga ttattggggc tattttgttg agaatctttg ttttttcaac
      241 ttttaaagtt tctccagaaa cagctaatac ttatttaaag agtggtgatt tagtcacaat
      301 caaaaaaaat attcagccca aatataaaga ttttgtggtt tatagagttg gaaaaaaaga
      361 ttatgtcagt cgagtcattg ctgttgaagg cgatagcgtg acttatatgg acgatatttt
      421 ttacctcaat aatatggtag agtcacaggc ttaccttgaa aagatgaaag cacattactt
      481 gaatcatgca ccgtttggca cattgtatac agatgatttt acagttgcta ccatcacagc
      541 tgataagtat caaaaagttc ctaaggggaa gtatcttctt ttgaatgata accggaaaaa
      601 tacgaatgac agtcgtcgat ttgggttaat aaatgcctcg cagattaaag gtttagtgac
      661 ctttagagtt ttgcctctca gcgattttgg atttgtagaa gtagagtagt tgtcaggcta
      721 ctctactttt tttataatta gactatacca attttatgtt tgacaagaca ttgtggatat
      781 tatatactgt aaacatactg tttttatcgg tataatatga ctataccaat tattgaaatt
      841 atgagagaaa gtagcaagtt aacgaacttg ttaaggtaat taagatgtgt ggaattgttg
      901 gagttgttgg aaatcgcaat gcaacggata ttttaatgca aggccttgaa aagcttgaat
      961 accggggtta tgattcagca ggaatttttg tggctaatgc caatcaaaca aacttgatta
     1021 aatcagtggg gcggattgct gatttgcgtg ccaagattgg cattgatgtt gctggttcaa
     1081 cagggattgg tcacacccgt tgggcaacgc atggccaatc aacagaggat aatgcccatc
     1141 ctcacacgtc acaaactgga cgttttgtac ttgttcataa tggtgtgatt gaaaattacc
     1201 ttcacattaa aacagagttc ctagctggac atgattttaa ggggcagaca gatactgaga
     1261 ttgcagtaca cttgattgga aaatttgtgg aagaagacaa gttgtcagta ctggaagctt
     1321 ttaaaaaagc tttaagcatt attgaaggtt cctacgcctt tgcgttaatg gatagccaag
     1381 caactgatac tatttatgtg gctaaaaaca agtctccatt gttgattgga cttggtgaag
     1441 gttacaacat ggtttgttca gatgccatgg ccatgattcg tgaaaccagt gaatttatgg
     1501 aaattcatga taaggagcta gttattttaa ccaaagataa ggtaactgtt acagactacg
     1561 atggtaaaga gctgatacga gattcctaca ctgctgaatt agacttatct gatattggca
     1621 aagggactta tcctttctat atgctgaaag aaattgatga gcaaccaacc gtaatgcgtc
     1681 aattaatttc aacttatgca gatgaaactg gtaacgtaca ggttgatcca gctatcatta
     1741 cctctatcca agaggctgac cgtctttata ttttagcggc agggacttcc taccatgctg
     1801 gttttgcaac aaaaaatatg cttgagcaat tgacagatac accagttgag ttgggagtgg
     1861 cttctgagtg gggttaccac atgcctctgc ttagcaagaa accaatgttt attctactaa
     1921 gccaatcagg agaaaccgca gatagtcgtc aagttttagt aaaggcaaat gctatgggta
     1981 ttccgagttt gacagtaact aacgttccag gatcaacctt atcacgtgaa gcaacataca
     2041 ccatgttgat tcatgctgga cctgaaattg ctgttgcgtc tacaaaagct tacactgcac
     2101 aacttgctgc ccttgccttt ttggctaagg cagttggtga ggcaaatggt aagcaagaag
     2161 ctcttgactt taacttggta catgagttgt cattggttgc ccaatctatt gaggcgactt
     2221 tgtctgaaaa agatctcgtg gcagaaaagg ttcaagcttt gctagctact actcgtaatg
     2281 ctttttacat tgggcgtggc aatgattatt acgttgcgat ggaagctgct ttgaaattaa
     2341 aagagatttc ttatattcaa tgcgaaggct ttgcggctgg tgaattgaaa catggaacca
     2401 tttcattgat tgaggaggac acgccagtaa tcgctttaat atcgtctagt cagttggttg
     2461 cctctcatac gcgtggtaat attcaagaag ttgctgcccg tggggctcat gttttaacag
     2521 ttgtggaaga agggcttgac cgtgagggag atgacattat tgtcaataag gttcatcctt
     2581 tcctagcccc gattgctatg gtcattccaa ctcaactgat tgcttactac gcttcattac
     2641 aacgtggact tgatgttgat aagccacgta atttggctaa agctgtaaca gtagaataaa
     2701 tgattataat ggataaggca accatctgtt aggtggttgc tttttgtttt taggagaata
     2761 gcagagctta gaaaatggcc ttgagaaaag ctatacaaga agaatagtca tcttctgatg
     2821 agaacgtatt catcttgtca aatcattgat tctaaagtaa aatggtaaca ttaagaaatg
     2881 tttaggagtg taagatgtca ttaccaaatt gtttgcaatg ccagtctgaa tatgtttacg
     2941 aagatggtct tttattaatc tgtccaatgt gtgcttttga atggacacca ggcgaagaag
     3001 cgactgaaga agaaggactt gttgttttgg atagcaatgg tgtccgactg tctgatggtg
     3061 ataccattac tgtggttaaa gatttgaaag taaaaggcgc tccaaaagac ctgaaacaag
     3121 ggactcgagt taaaaatatt cgcctggtgg aaggtgatca taatattgat tgtaagattg
     3181 atgggtttgg cgcgatgaaa ttgaaatcag aatttgtcaa gaaaatctaa taataatacg
     3241 caaccagctg atctggttgt atttttataa aaaacctctc cccaaatacg ttcaaatttg
     3301 gtataatagt aaaatattca gttttaggag gcaacatgac ctatattcag caagttttac
     3361 ccagcttatt agatggtgcc ttggtgacct tacaagtatt ctttattgtt atcattcttt
     3421 ctataccctt aggggctatt ttagctttct tgatgaagat tccctttaaa ccgctacagt
     3481 ggtttttgac cctatacgtg tggatgatgc gagggacacc attactactt caattgattt
     3541 ttttctatta tgttttgcca agtgtgggga ttagttttga tcgaatgcca gctgctattt
     3601 tggcgtttac tttgaattat gctgcctact ttgctgaaat ttttagaggt gggattgagg
     3661 ctattccaaa aggtcaatat gaagcagcta aagtattaaa gttaaaacct cttcaaacca
     3721 ttcgttatat tattttgcct caagtgttta aaattgtgtt accaagtgtt ttcaatgaag
     3781 tcattaattt ggtcaaagat tcttcccttg tctatgtact cggtgtagga gatcttttat
     3841 tagcaagtaa gacggcagcc aatagggatg caaccttagc ccctatgttt atcgctggtc
     3901 ttatctattt gcttttaatt ggactggtca cgattatttc aaaacaagtt gaaaaacggt
     3961 ttaattatta tcagtaagga ggcttcatgt tagaactcaa aaatatttcc aaacagtttg
     4021 gtcaaaaaac catttttgat ggctttaatc taaccgttca agacggagaa gtgctctctt
     4081 tgctaggccc atcaggtggc ggtaagacaa cactcttacg gatgttggct ggtcttgaat
     4141 ctattgattc aggtcaagtc ttttacaatg gcgaagatgt tggtattgat catttggaaa
     4201 atcgtaactt gcttggattt gtttttcaag attttcaatt gtttcctcat cttaccgttt
     4261 tagacaacct aacgctgtct ccaacaatta caatgggcaa gcaaaaatct gacgctaaag
     4321 aaaaggcttt ggatttactg gcacgtttag gattaaaaga acatgcccaa gtttatccct
     4381 attcgttatc tggaggtcaa aaacaacggg ttgctttggc aagagccatg atgattgacc
     4441 ctcaaattat cggttacgat gaaccgacca gtgctctaga tcctgaatta cgtcagacgg
     4501 tagaagcctt gattgttcaa aaccgtgaaa tgggaataac tcaaattgta gtcactcacg
     4561 atcttgtttt tgccgaagcc atctcagatc gtattattag ggttaatcct aaatagaaga
     4621 ggacccaaaa gatgattata aaaaaaagaa ccatagcaat tttagccata gctagtagct
     4681 ttttcttggt agcttgtcaa gctactaaaa gtcttaaatc aggagatgct tggggagttt
     4741 accaaaagca aaaaagtatt acagttggtt ttgacaatac gtttgttcct atgggctata
     4801 aggatgaaag cggcaaatgc aaaggttttg atattgattt ggctaaagaa gtttttcacc
     4861 aatatggact caaggttaac tttcaagcta ttaattggga catgaaagaa gcagaactaa
     4921 acaatggtaa aattgatgta atctggaatg gttattcaat aactaaggag cgtcaggata
     4981 aggttgcctt tactgattct tacatgagaa atgaacaaat tattgttgtc aaaaaaagat
     5041 ctgatatcaa aacaatatca gatatgaaac ataaagtgtt aggagcacaa tcagcttcat
     5101 caggttatga ctccttgtta agaactccta aactgctgaa agattttatt aaaaataaag
     5161 acgctaatca atatgaaacc tttacacaag cttttattga tttaaaatca gatcgtatcg
     5221 atggaatatt gattgacaaa gtatatgcca attactattt agcaaaagaa gggcaattgg
     5281 agaattatcg gatgatccca acgacctttg aaaatgaagc attttcggtt ggacttagaa
     5341 aagaagacaa aacgttgcaa gcaaaaatta atcgtgcttt cagggtgctt tatcaaaatg
     5401 gcaaatttca agctatttct gagaaatggt ttggagatga tgttgccact gccaatatta
     5461 aatcttaaaa aggacacttg tccttttttt gtttaacagg tgagatctag cagacaaagt
     5521 cagct
//
LOCUS       DAUGSW010000060         5154 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUGSW010000060 DAUGSW010000000
VERSION     DAUGSW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.060"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            101..1649
                     /locus_tag="VIB18_001533"
     rRNA            101..1649
                     /locus_tag="VIB18_001533"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1701..1773
                     /locus_tag="VIB18_001534"
     tRNA            1701..1773
                     /locus_tag="VIB18_001534"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1734..1736,aa:Ala,seq:tgc)
     gene            2072..4974
                     /locus_tag="VIB18_001535"
     rRNA            2072..4974
                     /locus_tag="VIB18_001535"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5060..>5154
                     /gene="rrf"
                     /locus_tag="VIB18_001536"
     rRNA            5060..>5154
                     /gene="rrf"
                     /locus_tag="VIB18_001536"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1464 a         1060 c         1479 g         1151 t
ORIGIN      
        1 agacgaacca aacgtgaggg tgatatggag acatattacc cgtcaagaaa cgagaaataa
       61 atctgtcagc gacagaagga acgagtaagt tcaaacgcaa attaaagaga gtttgatcct
      121 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gagaactggt
      181 gcttgcaccg gttcaaggag ttgcgaacgg gtgagtaacg cgtaggtaac ctacctcata
      241 gcgggggata actattggaa acgatagcta ataccgcata agagagacta acgcatgtta
      301 gtaatttaaa aggggcaatt gctccactat gagatggacc tgcgttgtat tagctagttg
      361 gtgaggtaaa ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
      421 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
      481 tgggggcaac cctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
      541 tctgttgtta gagaagaatg atggtgggag tggaaaatcc accaagtgac ggtaactaac
      601 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
      661 tccggattta ttgggcgtaa agcgagcgca ggcggttttt taagtctgaa gttaaaggca
      721 ttggctcaac caatgtacgc tttggaaact ggagaacttg agtgcagaag gggagagtgg
      781 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
      841 ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
      901 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt aggccctttc cggggcttag
      961 tgccggagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1021 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1081 aagaacctta ccaggtcttg acatcccgat gcccgctcta gagatagagt tttacttcgg
     1141 tacatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     1201 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttaagttggg cactctagcg
     1261 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     1321 gacctgggct acacacgtgc tacaatggtt ggtacaacga gtcgcaagcc ggtgacggca
     1381 agctaatctc ttaaagccaa tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     1441 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     1501 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctatta
     1561 ggagccagcc gcctaaggtg ggatagatga ttggggtgaa gtcgtaacaa ggtagccgta
     1621 tcggaaggtg cggctggatc acctcctttc taaggaaatg gaacacgttt atcgtcttat
     1681 ttagttttga gaggtcttgt ggggccttag ctcagctggg agagcgcctg ctttgcacgc
     1741 aggaggtcag cggttcgatc ccgctaggct ccatcaggat acaatcctac taaacttaat
     1801 acaagtgaag ttgaacacgc aactcacttc ctaggaaaat agacaatctt cccttgtgtg
     1861 caaggcccac atggttagat tcctaatttt ctacagaagt ttcgctaaag cgagcgttgc
     1921 ttagtatcct atataatagt ccattgaaaa ttgaatatct atatcaaatt ccacgatcta
     1981 gaaatagatt gtagaaaagt aacaagaaaa taaaccgaaa acgctgtgac tatttaataa
     2041 gttttctagt ttaaaaaaac taggttaata aggttaagtt aataagggcg aacggtggat
     2101 gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt ggggagctgt
     2161 aagtaagcgc tgatccagag atgtccgaat gggggaaccc actaactaat ggttagtatc
     2221 cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta agtagctgca
     2281 ggaagagaaa gcaaacgcga ttgccttagt agcggcgagc gaaacggcag gagggcaaac
     2341 cgaagtgttt acacttcggg gttgtaggac tgcgacgtgg gactttaaaa ggatagaaga
     2401 attacctggg aaggtaagcc aaagagagta aaagcctcgt atttaaaatt cttttgagcc
     2461 ctagcagtat cctgagtacg gcgagacacg tgaaatctcg ttggaatctg ggaggaccat
     2521 ctcccaaccc taaatactct ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgatatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtcttaatag ggcgatttag
     2761 tatcatgttg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgaggtaa
     2821 aactcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgatgtt aagtctcttg gaggtagagc actgtttggg tgaggggtcc atctcggatt
     3001 accaatctca gataaactcc gaatgccaac gagatatcat cggcagtcag actgcgagtg
     3061 ctaagatccg tagtcgaaag ggaaacagcc cagaccacca gctaaggtcc caaaataact
     3121 gttaagtgga aaaggatgtg gggttgcaca gacaactagg atgttagctt agaagcagct
     3181 attcattcaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
     3241 ggggctaaaa cagtttaccg aagctgtgga tgacacaaaa gtgtcatggt aggagagcgt
     3301 tctatgtgtg aagaaggtgt accgtgagga gcgctggaac gcatagaagt gagaatgccg
     3361 gtatgagtag cgaaagacag gtgagaatcc tgtccaccgt aagactaagg tttccagggg
     3421 aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt gtatccgatg
     3481 gccaacaggt tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa
     3541 ctaaaccgga cgattggaag agtccggcta agcagtgagg tgtaagatga gtcaaatgct
     3601 tatctttata acattgagct gtgatgggga gcgaatttta gtagcgaagt tagtgatgtc
     3661 acactgccaa gaaaagcttc tagcgtttaa tgatactcta cccgtaccgc aaaccgacac
     3721 aggtagtcga ggcgagtagc ctcaggtgat cgagagaact ctcgttaagg aactcggcaa
     3781 aatgaccccg taacttcggg agaaggggtg ctgacttagg tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagggttta gcgcaagcga agatctgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac
     4081 tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc
     4141 atggagcttt actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga
     4201 gccattgact tcgggacgcc agtttcgaat gaggcgttgt tgggatacta cccttgtgtt
     4261 atggctactc taacccagat aggttatccc tatcggagac agtgtctgac gggcagtttg
     4321 actggggcgg tcgcctccta aagagtaacg gaggcgccca aaggttccct cagattggtt
     4381 ggaaatcaat cgcagagtgt aaaggtataa gggagcttga ctgcgagagc tacaactcga
     4441 gcagggacga aagtcgggct tagtgatccg gtggtaccga atggaagggc catcgctcaa
     4501 cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg
     4561 gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt
     4621 tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc
     4681 ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac
     4741 cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct gggtagctat
     4801 gtagggaagg gataagcgct gaaagcatct aagtgcgaag cccccctcaa gatgagattt
     4861 cccatgattt tatatcagta agagccctga gagatgatca ggtagatagg ttaggagtgt
     4921 aagtgtagcg atacatgtag cggactaata ctaatagctc gaggacttat ccaaaaagaa
     4981 atattgacaa cgttacggat tcttgttaga ctatagatat tcaattttga gtgggttatg
     5041 aaaatagcac atttacaagt taagtgacga tagcctagga gatacacctg tacccatgcc
     5101 gaacacagca gttaagccct agaacgcctg atgtagttgg gggttgcccc ctgt
//
LOCUS       DAUGSW010000061         5041 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUGSW010000061 DAUGSW010000000
VERSION     DAUGSW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5041
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.061"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(1..143)
                     /locus_tag="VIB18_001537"
                     /pseudo
     CDS             complement(1..143)
                     /locus_tag="VIB18_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(326..643)
                     /locus_tag="VIB18_001538"
     CDS             complement(326..643)
                     /locus_tag="VIB18_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="role in replication"
                     /protein_id="HEQ8766527.1"
                     /translation="MLTLYKRQIAEVWEIGRETPQPEWVRDAFRKNYICWLDEHVRIL
                     MTGLNPSLTTNLKIGATGTVGGGFAGYGMYVLGYPGDFLDVTNHRVISAKKFHKEYQI
                     IDG"
     gene            complement(692..919)
                     /locus_tag="VIB18_001539"
     CDS             complement(692..919)
                     /locus_tag="VIB18_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ8766528.1"
                     /translation="MNTKTMEQFEVMNSEMLAGVEGGWGGWGEAIAGLLGGFAPSPTL
                     DQLNGKWPIRKPSKPCSPYGTGGTPNACNGL"
     gene            complement(1530..1892)
                     /locus_tag="VIB18_001540"
     CDS             complement(1530..1892)
                     /locus_tag="VIB18_001540"
                     /inference="COORDINATES: protein motif:HMM:NF014566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8766529.1"
                     /translation="MHYFYNTLLLFSVTLSEMSYQPVKFILFFFTTVVSQPILEEILF
                     RGILQEKLSRVSFWLSIIVTSVVFSYIHGNDTILNTQFISSLIYGMAYQTSKDLRFPI
                     INHSLQNLIVLLTVVLLK"
     gene            complement(2136..2312)
                     /locus_tag="VIB18_001541"
     CDS             complement(2136..2312)
                     /locus_tag="VIB18_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766530.1"
                     /translation="MGRLVGGNNHGYQKFFAWFSYWFTLPNFRQYIIEYPEKLEKPIE
                     DTKMGLYSVYIGDL"
     gene            complement(2290..2514)
                     /locus_tag="VIB18_001542"
     CDS             complement(2290..2514)
                     /locus_tag="VIB18_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ8766531.1"
                     /translation="MNTTIKQFEIMDEAMLTGIEGGCSWHGLAQAAVFTGAGNGFRLG
                     VKTRTWQGAAAGAAGGLVIGGVGYGATCWW"
     gene            2812..3048
                     /locus_tag="VIB18_001543"
     CDS             2812..3048
                     /locus_tag="VIB18_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766532.1"
                     /translation="MTSCKRTFVPQIDARDCGIAALASIAKFYGSDYSLTHLRELAKT
                     NKEGTTTLGIVKAAKEMGFEKNISSLEIQIPPLK"
     gene            3153..3863
                     /locus_tag="VIB18_001544"
     CDS             3153..3863
                     /locus_tag="VIB18_001544"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766533.1"
                     /translation="MSFLPLIFKQESLIFYIVLASLLVTLINIGGSYYLQGIWDEYIP
                     NQMKPTLGIISIGLIVTYILQQMMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSF
                     FVTRRTGEIISRFTDANAIIDALASTILSLFLDVSILSIVGGVLLVQNTNLFLLSLIS
                     IPIYIIIIFTFMKPFEKMNNNVMQSNSMASSAIIEDINGIETIKSLTSEEIRYQKIDS
                     EFVDYLDKSFKLSKYSTK"
     gene            4086..4532
                     /locus_tag="VIB18_001545"
     CDS             4086..4532
                     /locus_tag="VIB18_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8766534.1"
                     /translation="MSYKYCFGRDALSDISLTIKEGEKVSIVGISGSGKTTLAKMIVN
                     FFEPYEGQISINHQNLKMIDKKVLRQHINYLPQQAHIFSGSILENLTLGANHSTSQED
                     ILINIRNDIHILKFDTYFQTGQNIKKEKRIKRKIFHSYFIYIYFSM"
     gene            complement(4590..4991)
                     /locus_tag="VIB18_001546"
                     /pseudo
     CDS             complement(4590..4991)
                     /locus_tag="VIB18_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638212.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
BASE COUNT         1667 a          965 c          745 g         1664 t
ORIGIN      
        1 aagacctgga acttttttag aagagctaat tcctcctgta gcagtttgtt ctctttttca
       61 agttttttta tctcaaattg agcatgacga agtgcgctcc catgtcctgg gaacgcactt
      121 tctccatatt tttcatattc ttgaatccat tgataaagac tattgggatg aatttttaaa
      181 gttgaactaa ttatctttgt accaaataga tgatgaataa atgaaaaccg acaaagaaaa
      241 tacttcctac aatcttccaa agagctcctt tttgttgtaa accctcaaaa ttaaaccagt
      301 cataaaagtt catagtctac tttttctatc catcaataat ctgatattct ttatggaatt
      361 ttttggcaga aataactcga tggttggtca catccaagaa atcacctgga taaccaagga
      421 catacatacc atatccagca aatcctccac ctactgttcc tgttgcacca atctttaaat
      481 ttgttgtcag cgaaggattt agtccagtca tgagaatacg aacatgctca tccaaccaac
      541 agatgtaatt cttgcgaaaa gcatcacgta cccactctgg ctgaggcgtt tctctcccaa
      601 tctcccaaac ttctgcgatt tgtcttttgt atagagtcag catatctacc tccacttcct
      661 ttattgcata atcacttaaa tatgtcctaa tttataaacc attacacgca ttaggtgtcc
      721 caccagttcc gtaaggacta caaggtttgg aaggttttct aattggccat ttgccattta
      781 attgatctaa tgttggtgaa ggagcaaagc ctcctaatag accggcaatt gcttctcccc
      841 aaccgcccca gcctccttca acaccagcaa gcatttcaga gttcatcact tcaaattgtt
      901 ccattgtttt cgtattcatc atgaatatct ccttatataa tttttatatt ttgtccagtt
      961 gcaaccttga catattcagt atagcgcttc ttaaaaaaat cctgcactat ttcctaaaca
     1021 gtcatttaac tttcctaaat gggaagtctt tttaacattc ataatttcaa aaacacccat
     1081 attatcttaa ttttatatcc atgagtccaa gactcactct accattcaag atgtttcgat
     1141 gtccgtttaa gatatagtca taaacaaaat gcaaagccag cgaaatgcct ctaagttctc
     1201 tctcctattc cctagaaagc aaggtcagta tacatagctt ggctttgaca taaaatgctt
     1261 attatactaa cgaagctaca aatccgacaa catagtcaac cgcatcttta ataacattaa
     1321 cggaaagtgt aatctgaaac tacaattttt tgcccaagaa gcttcttttt ccagatgcgt
     1381 cctgtaatca aaccaacaca ataacttttt tgggagccac ctgaaatact tgttagctca
     1441 gtcatattta tttcactaaa ttattttgtc attgtcaaaa tcttttcatt actataatta
     1501 tcccagttat ttttattaat tctcactact tactttagca aaacaactgt aagaagtact
     1561 attaaattct gcagagaatg gttaataata ggaaatctta aatccttact tgtttgataa
     1621 gccattccat atatcaaaga actgatgaat tgagtattca atatagtgtc atttccatga
     1681 atatacgaga atactacaga tgtcacaatg atgcttaacc aaaacgaaac gcgtgataac
     1741 ttttcttgca gtattcctcg aaatagaatc tcctccaaga ttggttgaga aactacagtc
     1801 gtaaaaaaaa ataatatgaa ctttactggc tgataagaca tttcgctaag agtgacagaa
     1861 aataaaagca aagtattata aaaataatgc aaattattac tcttaaaaag tctccattga
     1921 tcccttacct aagattaatc cgttcattgt taaatgtcgc aacaactgga gtttgaacaa
     1981 aaatagtcat aaatatagag aatataattg acataataaa ggtaagacac ttcttaaaga
     2041 caccactcat tctatttgct cctatttttt aacatttacc agtatacttt ttcttattcc
     2101 aacgagacct atcacatcca agctatgtta aatccttaaa gatcacctat ataaactgag
     2161 taaagcccca tcttagtgtc ttctatcggt ttttccaatt tttcaggata ttcaataata
     2221 tattgtcgaa aattgggcaa agtaaaccaa taactaaacc aagcaaaaaa cttttgatat
     2281 ccatggttat taccaccaac aagtcgcccc ataaccgact cctccaatga ccagtccacc
     2341 agctgctcca gctgcagctc cttgccaagt ccttgtttta acacctaatc taaatccatt
     2401 tccagcacca gtaaaaacag ctgcctgagc taacccatgc catgaacaac caccttcaat
     2461 accagtaagc atggcctcat ccataatttc aaattgttta attgttgtat tcataacgaa
     2521 tatctcctta tataattttt tattatgtct tgttgcaacc ttgacatgtt cagtatagca
     2581 tcttaagaaa tctgtgcccc gtaaaatctt caaatgttct tttttcatca tgaaatgatt
     2641 tttttcatag ttttttaatc gtttcgaatt agaaaataat cactagaaac ttattacttt
     2701 taattttaaa ataccattca ggatatacta gataccattt aagaattttc gaatttctta
     2761 tcagtagttt tgcaataatg agtttgtaat ttactggaag gaaatatatt aatgacatca
     2821 tgtaaacgta cgtttgtacc acaaattgat gcaagagatt gtggaattgc tgctctagct
     2881 tcgattgcaa aattctacgg gtctgactac tctttgacac atctgagaga attggcaaag
     2941 actaataaag aaggaacaac aacccttgga atcgtaaaag cggccaagga gatgggcttt
     3001 gaaaagaaca tttcatcatt ggagatccag atccctccgt taaagtaacc aaaatgagca
     3061 aagaaaaatt tgctcctgaa tagacagggg ttgctatctt tttagcacct gaacctggct
     3121 ataaacctca caaggataaa aagaatggct taatgagttt tctacctcta atttttaaac
     3181 aagagtcctt aatcttctat atcgttttag cgagcctctt agttaccctg ataaatattg
     3241 gtggttccta ctatctacaa ggtatttggg atgaatatat tccaaatcag atgaagccaa
     3301 cactcggtat aatctcaatt ggacttatcg ttacctatat cctacaacag atgatgagtt
     3361 tttcgcgaga ttatctcctg actgtactga gtcagcgatt aagcattgat gttattttat
     3421 cctatattcg tcatattttt gagcttccca tgtctttctt tgtaacacgt cggacaggag
     3481 aaatcatctc acgttttaca gatgctaatg ctattattga tgcacttgct tctacaattc
     3541 tatctctatt tttagatgtc tctattttaa gtattgtagg tggtgtgtta ctcgtacaaa
     3601 acactaacct atttcttcta tcattaattt ctatcccaat ctacattatc atcattttta
     3661 cttttatgaa accttttgaa aagatgaata acaatgtcat gcagagtaat tccatggcca
     3721 gctctgctat tatcgaagat attaatggta ttgaaacaat caaatcattg actagcgagg
     3781 aaattcgtta tcagaaaatc gatagtgaat ttgtagacta tttggataaa tcttttaagt
     3841 taagtaagta ttctacaaag tagtctaaag caaggagcac aactcatttt aaacgttact
     3901 atcttatggg tgggtgcacg actagttatg aatgataaaa tatcattaat cttcaaacta
     3961 aactgcaatc cgctaaggta gctaataatc gtctcaatga agtttacctg gttaaatctg
     4021 agttccaaaa agaacaggca ttaacagata cctattgtct atatggagat atccaatttg
     4081 cagacttgtc ttataaatac tgctttggtc gtgatgcctt atctgatatc agtttgacca
     4141 ttaaggaggg tgaaaaagtc agtatagttg gtattagtgg ttctggcaag acaacattag
     4201 ctaaaatgat tgttaatttc tttgaacctt acgagggaca gatttctatt aatcatcaaa
     4261 atcttaaaat gattgataaa aaagtgcttc gtcagcatat caactatctc ccccaacaag
     4321 ctcatatctt tagtggatct atcttagaaa acttaaccct aggtgccaat cactccacta
     4381 gtcaagagga cattctgata aatatcagaa acgatattca tatcttgaaa ttcgatacct
     4441 atttccaaac tgggcagaat ataaaaaaag aaaagcgtat aaagcgaaag atttttcaca
     4501 gttactttat atacatatac tttagcatgt aaaattatca aaataatgac atgagtaaaa
     4561 gtaagtgcta gaaagaagat gctactcatc taagtctctt tattatgtag attttcaact
     4621 gcttctttta gagcagtaac ttttagcctt gatactagac aagatgaacc gtttttttaa
     4681 ataaacctta cgttctaatc gttgtattga agatatattg tagggattaa caacaaatga
     4741 tcgatggcat tgaaataatc ttggttcttg cttaacgatt tcagataact ccccataaaa
     4801 ttcaatcctt tctctagtag aataaagaac caatttatga gcaatatatg acgtttcaat
     4861 ataaagtaag tctgcaaatg gaatctgaat ggaatctgaa cctgagtctt ggcatcttta
     4921 aaaataaagg agtcttcagc taacgtttga ccttgttgat gatggacata gtcaattgat
     4981 tgttcaatac gtggaaaaaa ttatgatagt tattcaagtc ttacatcgtt ctcttttagg
     5041 a
//
LOCUS       DAUGSW010000062         4763 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUGSW010000062 DAUGSW010000000
VERSION     DAUGSW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4763
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.062"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            51..1247
                     /locus_tag="VIB18_001547"
     CDS             51..1247
                     /locus_tag="VIB18_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8766535.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
     gene            1500..2462
                     /locus_tag="VIB18_001548"
     CDS             1500..2462
                     /locus_tag="VIB18_001548"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8766536.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            2648..3403
                     /gene="recO"
                     /locus_tag="VIB18_001549"
     CDS             2648..3403
                     /gene="recO"
                     /locus_tag="VIB18_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEQ8766537.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            3506..4513
                     /gene="plsX"
                     /locus_tag="VIB18_001550"
     CDS             3506..4513
                     /gene="plsX"
                     /locus_tag="VIB18_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEQ8766538.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            4506..4748
                     /locus_tag="VIB18_001551"
     CDS             4506..4748
                     /locus_tag="VIB18_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8766539.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMGDVLDYLVQRLT"
BASE COUNT         1544 a          736 c          992 g         1491 t
ORIGIN      
        1 tttttggtaa aatataagat gtcttatcga aaaggagtag tttttttatt atgaaaaaaa
       61 gaattttatc agcagttctt gtaagtggtg ttaccctcgg agcagctaca actgtaggag
      121 cggaggattt aagtactaag attgctaagc aagattctat tatctcaaat ctgactacag
      181 agcaaaaagc tgcacagaat caagtttcag cgttacaggc tcaagtaagt tcactacaat
      241 ctgaacaaga taaactgacc gcaagaaata cagaacttga ggcgctttca aagcgatttg
      301 agcaagaaat taaggctcta acaagtcaaa ttgttgctcg taatgaaaaa ttaaaaaatc
      361 aagctcgtag tgcttataaa aacaatgaaa cttctggtta tattaatgca cttttgaatt
      421 ctaaatcaat ttctgatgtt gtaaaccgtt tagtagcaat taatagagct gtctctgcta
      481 acgctaaatt gttagaacaa caaaaagctg ataaagtttc ccttgaagaa aagcaagctg
      541 ctaaccaaac agctattaat accattgccg ctaatatggc aatggctgaa gaaaaccaaa
      601 atacattacg tactcaacaa gctaatttgg tagctgcaac tgcaaattta gctctccaat
      661 tagcatctgc tactgaagat aaagctaatt tggtagctca aaaagaagct gcagaaaaag
      721 ctgctgctga agccttagca caagaacagg ctgctaaagt taaggcacaa gagcaggctg
      781 cacaacaagc agcatctgtt gaagcagcaa aatctgctat tactccagca ccacaagcta
      841 ctccggcagc gcaaagtagt aatgctattg aaccagctgc actcacggct ccggcagctc
      901 cttctgcagg accacaaaca tcatatgatt cttctaatac ttatccagtt ggacaatgca
      961 catggggagc taaatcttta gctccttggg caggaaataa ttggggaaat ggtggtcaat
     1021 gggcttatag tgctcaagca gctggttatc gtactggttc aacgccgatg gtaggtgcga
     1081 ttgccgtttg gaacgatggt ggttatggac atgtcgccgt tgtagttgag gttcaaagtg
     1141 cctcaagtat tcgtgtgatg gagtctaact acagtggtag acagtacatt gctgaccacc
     1201 gtggctggtt taatccaaca ggtgttacat ttatttatcc acactaacat attatttagg
     1261 ttagaacagt tgttctaacc tttttgatta ctcctattgt ggaatagttc tgagagtatt
     1321 gacgatatgg ttaatttata agagagttgt ttggccaatc gcttatgtat aatataagag
     1381 aagtatataa agtcgataaa aggtatattt aatacattct ttaacggttt ttcaatttca
     1441 tttgataatt cacttgaaaa gcgttaaaat ggtataggat taaaactttg gaggaaaaaa
     1501 tgtcttattc tgatttaaaa ttgtttgctt tatcgtcaaa caaggaatta gcagaaaaag
     1561 ttgcgtctgc aatgggtatt caacttggaa agtctacggt tcgccagttt tcagatggtg
     1621 aaatccaagt aaatattgaa gaatcaattc gtggtcatca tgtctttatt ttgcaatcaa
     1681 ctagctcacc tgtcaatgac aatttaatgg aaattttgat tatggtcgat gctttaaagc
     1741 gtgctagtgc tgaaaaaatt tcagttgtga tgccttacta cggctatgca cgccaagacc
     1801 gtaaagcgcg ttctcgtgaa cctattactt caaaattagt tgctaatatg ttagaagttg
     1861 ctggtgtaga tcgcttatta acggttgatt tacatgctgc tcaaattcaa gggttctttg
     1921 atattccagt tgatcacttg atgggtgcac ctttaattgc agactatttt gatcgtcatg
     1981 gtttagtggg tgaagatgtt gtcgttgtta gtcctgacca tggtggtgtg actcgtgcgc
     2041 gtaaattagc acaattcctc caaacaccaa ttgcaattat cgataagcgt cgtagtgtgg
     2101 ataagatgaa caccagtgaa gtgatgaata ttatcggaaa tgtttcgggc aagaaatgta
     2161 tcttgattga cgatatgatt gataccgcag ggactatttg ccatgcagca gatgcgcttg
     2221 ctgaagcggg ggcaacagct gtgtatgcgt catgcacgca tcccgttctt tctggaccag
     2281 cacttgataa tattcaacgt tcggctatcg aaaaactaat tgttcttgat actatttatc
     2341 tgccaaaaga acgtcttatt gataaaattg aacaaatttc aattgctgat ttggttgcag
     2401 aagcgattat tcgtattcat gaaaaacgtc cgttgtcacc tttatttgag atgggcaatt
     2461 aagcttaacg aagcctgaga taatagatct cgggcttttt gacttgaata aaatgtaagg
     2521 gtaatgtggt attaattatt gtgggatgaa ctatgcaatt ctaaaggatt ttgggtataa
     2581 taagaaagat aacaacagtt tattgtaaac taagataaaa ggtaagagaa aaatacgacg
     2641 aggtaatatg caactaacag aatcactagg catcgttctt tttaatagga attatcgaga
     2701 agatgataaa ttagtcaaaa tatttactga agtagcaggt aagcagatgt ttttcgtgaa
     2761 acatattagt cgttccaaaa tgtcctcaat cattcaacca ctaacgattg ctgattttat
     2821 tttcaagtta aatgatacag gcttgtctta tgttgttgac tatagtaacg ttaacactta
     2881 tcggtatatt aataatgata tttttcgatt agcctatgct agttatgtct tagcattagc
     2941 tgatgctgcg attgcagata atgaatcaga ttcgcatttg tttacgtttt tgaaaaaaac
     3001 acttgatttg atggaagagg gcctagatta tgaaattttg acaaatattt ttgaaattca
     3061 gatattagat cgttttggta ttagtctaaa ctttcatgag tgtgccattt gtcatcgcac
     3121 tgatttaccg cttgattttt cccatcgttt ttcagctgta ctttgttctg aacattatta
     3181 caaagacaac cgacgtaatc atttagatcc aaatgttatc tacttgttga gtcgatttca
     3241 aaaaatcaca tttgatgatt tgagaactat ttcattgaat aaagacatca aaaagaagct
     3301 tcgtcagttc attgatgagt tgtatcacga ctatgtagga atcaaattaa aaagtaaaac
     3361 attcattgat aatttagtta agtggggaga tattatgaaa tgatagggtc tctttcgttt
     3421 atgggaattg gtttcagaat atgctataat aaaaatacta ttaatagatt gtgtaagaac
     3481 acaagatata attaaaggag tggaaatgaa gagaattgca atagatgcta tgggtggaga
     3541 taacgctcct aaagctattg ttgagggtgt taatcaagca atagaagcat tttcagatat
     3601 cgaaattcaa ctttacggtg atcagacaaa gattaactcc tatcttattc aatcagatcg
     3661 tgttgctatt attcatacag atgaaaaaat tatgtcagat gatgaacctg caaaagctgt
     3721 tcgccgtaaa aagaaggctt caatggtttt agcagctaag gcagtgaaag aaggaaaagc
     3781 agatgccatt atttcagcag ggaatacagg tgctctttta gctgtaggtt tgtttgttgt
     3841 ggggcgtatc aagggagttg atcgtccagg attattatca actattccca cagtaaccgg
     3901 attaggattt gatatgttgg atcttggagc taatgctgaa aatacggcaa aacatttaca
     3961 tcaatatgct attttaggct ctttctatgc taagaatgta cgtgggattg ctaatccacg
     4021 tgttggtcta ttaaacaatg gtacagaaga aacaaaagga gatccccttc gtaaggccac
     4081 ttatgaactt ttaacagcag ataatacaat atcttttgtt ggtaatgtcg aggcgcgaga
     4141 acttatgtca ggtgttgcag atgttattgt atcagatggt ttcacgggaa acgcagtgtt
     4201 gaaatcaata gaaggaacag ctattagcat tatggggcaa ctgaaacaga taattaatag
     4261 cggcggtatt aagactaaaa ttggagctag tctacttaaa agtagtcttt acgagatgaa
     4321 gaagactctt gactactcta gtgctggagg tgcagtttta tttggtttaa aggcacctgt
     4381 tgtaaagtct catggttcta gtgatgtaaa agctattttt tcaacgataa aacaagtacg
     4441 tacgatgcta gacactaacg tggtcggaca attagtagaa gaatttgcta aggagactca
     4501 agtaaatgac tagacaggag atttttgaaa ggctgattaa cttaattcag aagcaaagaa
     4561 gctatttgag tgtagctatt acagaacaaa cacatttaaa aaatgattta gcggttgact
     4621 ctattgaact agttgaattt attattaatg ttgaagatga atttcatatt gctattcctg
     4681 atgaagatgt tgaggatatg gtatttatgg gagacgtttt agattattta gttcagcgtt
     4741 tgacttagtt agaataataa aaa
//
LOCUS       DAUGSW010000063         4661 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUGSW010000063 DAUGSW010000000
VERSION     DAUGSW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4661
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.063"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(30..715)
                     /locus_tag="VIB18_001552"
                     /pseudo
     CDS             complement(30..715)
                     /locus_tag="VIB18_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1166..3319
                     /locus_tag="VIB18_001553"
     CDS             1166..3319
                     /locus_tag="VIB18_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEQ8766540.1"
                     /translation="MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKT
                     NKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDVPYPFIVHVNKEGKFQHYYVIYQ
                     NKKNYLIIGDPDSTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
                     IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYIL
                     QQMMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANAII
                     DALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIVIIFIFMHPFEKMNN
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQS
                     SLKQGAQLILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQS
                     AKVANNRLNEVYLVDSEFQEAGTLVNQELLHGDIQFEELSYKYGFGRDTLSNINLTIK
                     QGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHINYLPQQ
                     AYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISA
                     RTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS"
     gene            3330..>4661
                     /locus_tag="VIB18_001554"
     CDS             3330..>4661
                     /locus_tag="VIB18_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEQ8766541.1"
                     /translation="MNPNLFKSAEFYHRRHHNFATFLILPSVLLVSFLVIFALFAKKE
                     ITITSQGELTPTKVIASVQSTSDHTIVVNNLKNNKFIKKGDVIIQYSKTMENSQKKAL
                     EKRLATLNKQKNGLQILRTSIEQETNLFKGEDEFGYSDTFNHFLKQTQDIIIGIAKKN
                     AEINNQASLANHAISVITSQLDELHQKITDYEELKQAINNQEYKLSPENPHQTALKKY
                     QTQFQAQEDNSALKEEYLSQIPQNISELESSMANLSIQRASTGNFSLPDTSHRIKIDI
                     LKTQFLQNASQQLTTVENQITELKNQIEQANIQLKNNIIIAPETGTIHLNSEFEGKSL
                     IPNGSEVAQIYPDIQKIKEVFITYYVTSEHVSLLKEKQGVRLSLEKVGNQTLTINGTI
                     QTIDKSATKTNQGNLFKVTALSKLSNKDSDVVQYGLQGRVTSVITRKSYFNY"
BASE COUNT         1567 a          864 c          747 g         1483 t
ORIGIN      
        1 tgtaaacaca agagtagagt ttttgaatat tagtcaaata agctatcaag tgtgtcaaaa
       61 catactccga atcctttatg aatacgagct ccgaacttaa tattatagtc ttcgaaaata
      121 cttacaagac atcgttctaa ggcttcttca tttggaaaaa ccaccctcct tcttgctttg
      181 tcgcttgatt tctttattga gtgattcaat caagtttgta gagtaaatac tagaccaaat
      241 gtaatgtgga aattgataga aagttaggag attttccgtt gtttcaagtg atgtcataac
      301 ctttttgtaa cgaggcttcc actcagaaac aagtggtgac catacatgcg cttaataatg
      361 tcactgattt cgcgtgtcgt aacgccagtc tgatagagtt tgatcactat ctcttccaag
      421 tggtcctctc gtctagcata agatggtaat aaaactggtg aaaactcgcc gtttcgatct
      481 cttgagatga ttaaattgac taagccatac tttgtttcaa actgacgaga ataagtccca
      541 ttacggctat tacctgtgtt gcaaccttct tttcataagg ttcataacca agaaaagctg
      601 atagttcaac ttgcaagagg tcattcatag ctatttctaa agaggagcga aaaaattcat
      661 caatatcttg tttttgtgct aggaagttaa gtaattctgt ggtaaactga gtcatgggaa
      721 taaatctctt tctagtaagt ttcgcaactc tactatacag gatttattcc tttttgtgtg
      781 tttacacaag atattttaca ctacccaatt accaccctca accttggcaa gcttttctat
      841 agtcatttga tgaaatgttt ccagtttctt tatctccata tcgaataact ccttttcata
      901 attcttaaat ttgtctcgtt gcaacctcga ctagtacaga atatcataaa gaacagtatc
      961 atggcttcaa aatcttaaaa ggccattttt tcatcatgaa atgtcttttt atcctctcta
     1021 cacttacgct gtgacaatag ttaattaatt aagaagttta aataatacca ttcatgcttt
     1081 tataaatacc ttttaagatt tttgataaaa actccctata tatatgtcat aatagcttag
     1141 tatttaatag aaaggtcttt tacaaatgat atcctatcga aaaacatttg ttgctcagat
     1201 tgatgctaga gactgtggtg tggctgctct tgcttccatc gctaaatatt acggttcaga
     1261 ctactcttta gctcatttaa gagagttagc taaaacaaat aaagagggaa caacagcgct
     1321 tggcatcgtc aaagctgcca aattaatggg atttgaaaca agagctattc aagcagacat
     1381 gaccctcttt gatatagaag atgtccctta tccttttatt gttcatgtta ataaagaagg
     1441 taaattccaa cactactatg tcatctatca aaacaaaaaa aattatctga taatcggcga
     1501 ccctgactcg acagtaaaag tcactaagat gacaaaggag cgatttactt ctgaatggac
     1561 gggtgtcgct atttttctag cacccgagcc cagctacaag cctcataagg acaaaaagaa
     1621 cggtctaata agctttttac ctctcatttt taaacagcga tctctgattt tctatatcat
     1681 attagctagc ctactcgtta ctctgattaa tattgtaggt tcttattacc tacaaggtat
     1741 attagatgac tatattccaa atcaactgaa atcaacactc ggcattattt caattggtct
     1801 tatcattacc tatatcctcc aacagatgat gagtttttcg cgagattatc tcctgactgt
     1861 actgagtcag cgattaagca ttgatgttat tttatcctat attcgtcata tttttgagct
     1921 tcccatgtct ttttttgcaa ctcgcagaac aggagaaatc atctcacgtt ttacagatgc
     1981 taatgctatt attgatgcac tcgcttctac tattttgtct ctttttcttg atgtcagtat
     2041 tttaactatc gtagggacag tcctgttagt gcaaaatacc aatctttttc ttctatctct
     2101 ggtttcagtc cctctatata ttgttattat ctttatattt atgcacccat ttgaaaagat
     2161 gaataatgat gtcatgcaga gtaactctat ggttagctca gccattatcg aagatatcaa
     2221 tggcattgaa actattaaat cactgaccag tgaagaaaat cgttatcaga aaattgatag
     2281 tgaatttgtg gactatctgg ataaatcctt caagttaagt aagtactcta ttttacaaag
     2341 cagtctcaaa caaggggcgc aactaatcct taacgtgata gtcttatggt ttggggccaa
     2401 attagttatg ggaggaaaaa tttctgttgg tcagttgatt acgtttaata ctctcttatc
     2461 ttattttacc aatcctttag aaaatatcat taatcttcaa actaaactgc aatcagccaa
     2521 ggtagctaat aatcgtctca atgaagttta cctagtcgat tctgagtttc aagaggctgg
     2581 gacattagtc aatcaagaat tattacacgg agacattcaa tttgaagagt tatcctataa
     2641 atatggcttt ggacgcgata ctctatcaaa tattaatctc actattaagc aaggggacaa
     2701 agttagcctt gttggtatta gtggatctgg taaaacgact ctagctaaaa tgattgttaa
     2761 tttttttgag ccttataacg gccgaattac cattaatcat aatgacttaa aaatgattga
     2821 taaaaaaagt cttcgccaac atattaatta tctcccccaa caagcctata tttttaatgg
     2881 ttctatttta gaaaatttaa ccttaggtgc taatgactgt actagtcatg aagatattct
     2941 aagagcttgt gaggttgcag aaattcgaca agatattgaa caaatgccta tgggctatca
     3001 aacagagctt tctgatggtg ccggactctc aggaggccaa aagcaacgaa ttgcacttgc
     3061 cagagctctc ctaaccaagg cgcctgtgct tattctagat gaggctacaa gcggtcttga
     3121 cgtactaact gaaaagaggg ttattgataa tcttttggct atgacggata aaactattat
     3181 tttcgtagct catcgtctca gcatttcagc gcggaccaat caagtcattg tgcttgatga
     3241 gggtaaaatt attgaaatag gatctcatca agaattaatg actaaacaag gtttctatca
     3301 tcatttattt agtagttaag gagaataaca tgaatccaaa cctttttaaa agtgcggaat
     3361 tttatcatcg acgtcatcat aactttgcaa ctttcttgat tttgccatcc gttttgttag
     3421 tgagcttctt agttattttt gctctctttg ctaaaaaaga aattaccatt acttcacaag
     3481 gagaattgac gccaacaaaa gttattgctt cagtccaatc aactagtgac catactattg
     3541 tcgtcaacaa tttaaaaaac aataaattta ttaagaaagg tgatgttatt atccaatact
     3601 caaaaacaat ggaaaattct caaaaaaaag ctttagaaaa acgattagcc actcttaaca
     3661 aacaaaaaaa tggactccaa atactcagaa ccagtataga acaagaaact aacttattta
     3721 agggagaaga tgaattcggc tatagcgata cgtttaatca ttttctcaaa caaacccaag
     3781 atataatcat tgggattgct aaaaaaaatg ctgaaatcaa taatcaagca agtcttgcta
     3841 atcatgccat ttcagttatt actagtcagc ttgacgaact tcatcaaaaa attacagatt
     3901 atgaagagct aaagcaagct attaataatc aagaatataa gctttcacct gagaatccac
     3961 atcaaactgc cctaaaaaaa tatcaaactc aatttcaagc acaagaagat aactcagctt
     4021 taaaagaaga atacctttct caaatcccac aaaatatctc agaacttgaa tcttcaatgg
     4081 caaaccttag tatccaacgt gctagtacag gaaatttttc tcttccagac actagtcata
     4141 ggatcaaaat agatatttta aaaacacaat ttctgcaaaa tgcttcccaa caacttacca
     4201 cagttgaaaa tcaaattact gaacttaaaa atcaaattga gcaagccaat attcagctaa
     4261 agaacaatat aattatagct cctgaaacag gaacgataca tctaaacagt gaatttgaag
     4321 ggaaatctct cattcctaat ggaagtgagg tggctcaaat ctacccagat atccaaaaaa
     4381 taaaggaagt attcattacc tactacgtca cttcagagca tgtctcattg ttaaaagaaa
     4441 agcaaggtgt tcgtcttagt cttgaaaaag ttggaaacca aactctaaca attaacggaa
     4501 cgattcagac tattgataaa tctgccacaa agactaatca aggtaatctc ttcaaggtta
     4561 ctgcactctc caaactttct aataaagaca gtgacgtcgt acagtatgga ttgcaaggac
     4621 gtgtaacaag tgtcattaca cggaaaagct atttcaatta c
//
LOCUS       DAUGSW010000064         4616 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUGSW010000064 DAUGSW010000000
VERSION     DAUGSW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4616
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.064"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            109..3135
                     /locus_tag="VIB18_001555"
     CDS             109..3135
                     /locus_tag="VIB18_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEQ8766542.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQVTSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNCIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTIGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSHPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            3155..3556
                     /locus_tag="VIB18_001556"
     CDS             3155..3556
                     /locus_tag="VIB18_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEQ8766543.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(3723..4598)
                     /locus_tag="VIB18_001557"
     CDS             complement(3723..4598)
                     /locus_tag="VIB18_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEQ8766544.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCTLHQELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIEVN"
BASE COUNT         1624 a          732 c          883 g         1377 t
ORIGIN      
        1 tggatattat taggtcgact agtgttcttt tcaataattt aatatcgtta ttattagtat
       61 cagccaatca aatgtggata agttggcttt tagaaaggtt ttaccacaat gaagaaacat
      121 cttaaaacag ttgccttgac cctcactaca gtatcggtag tcacccacaa tcaggaagtt
      181 tttagtttag tcaaagagcc gattcttaaa caaactcaag cttcttcatc gatttctggc
      241 gctgactacg cagaaagtag cggtaaaagc aagttaaaga ttaatgaaac ttctggccct
      301 gttgatgata cagtcactga cttattttcg gataaacgta ctactcctga aaaaataaaa
      361 gataatcttg ctaaaggtcc gagagaacaa gagttaaagg cagtaacaga gaatacagaa
      421 tcagaaaagc aggtcacttc tggatctcaa ctagaacaat caaaagagtc tctttcttta
      481 aataaaacag tgccatcaac gtctaattgg gagatttgtg attttattac taaggggaat
      541 acccttgttg gtctttcaaa atcaggtgtt gaaaagttat ctcaaactga tcatctcgta
      601 ttgcctagtc aagcagcaga tggaactcaa ttgatacaag tagctagctt tgcttttact
      661 ccagataaaa agacggcaat tgcagaatat accagtaggg ctggagaaaa tggggaaata
      721 agccaactag atgtggatgg aaaagaaatt attaacgaag gtgaggtttt taattcttat
      781 ctactaaaga aggtaacaat cccaactggt tataaacata ttggtcaaga tgcttttgtg
      841 gacaataaga atattgctga ggttaatctt cctgaaagcc tcgagactat ttctgactat
      901 gcttttgctc acctagcttt gaaacagatc gatttgccag ataatttaaa agcgattgga
      961 gaattagctt tttttgataa tcaaattaca ggtaaacttt ctttgccacg tcagttaatg
     1021 cgattagcag aacgtgcttt taaatcaaac catatcaaaa caattgagtt tagaggaaat
     1081 agtctaaaag tgatagggga agctagtttt caagataatg atctgagtca actaatgcta
     1141 cctgacggtc ttgaaaaaat agaatcagaa gcttttacag gaaatccagg agatgatcac
     1201 tacaataacc gtgttgtttt gtggacaaaa tctggaaaaa atccttatgg tcttgctact
     1261 gaaaatacct atgttaatcc tgataagtca ctatggcagg aaagtcctga gattgattat
     1321 actaaatggt tagaggaaga ttttacctat caaaaaaata gtgttacagg tttttcaaat
     1381 aaaggcttac aaaaagtaaa acgtaataaa aacttagaaa ttccaaaaca gcacaatggt
     1441 gttactatta ctgaaattgg tgataatgct tttcgcaatg ttgattttca aaataaaact
     1501 ttacgtaaat atgatttgga agaagtaaag cttccctcaa ctattcggaa aataggtgct
     1561 tttgcttttc aatctaataa cttgaaatct tttgaagcaa gtgacgattt agaagagatt
     1621 aaagagggag cctttatgaa taattgtatt gaaaccttgg aattaaaaga taaattagtt
     1681 actattggtg atgcggcttt ccatattaat catatttatg ccattgttct tccagaatct
     1741 gtacaagaaa tagggcgttc agcatttcgg caaaatggtg caaataatct tatttttatg
     1801 ggaagtaagg ttaagaccat aggtgagatg gcatttttat caaatagact tgaacatctg
     1861 gatctttctg agcaaaaaca gttaacagag attcctgttc aagccttttc agacaacgcc
     1921 ttgaaagaag tattattacc agcatcactg aaaacgattc gagaagaagc cttcaaaaag
     1981 aatcatttaa aacaactgga agtggcatct gccttgtccc atattgcttt taatgcttta
     2041 gatgataatg atggtgatga acaatttgac aataaagtgg ttgttaaaac gcatcataat
     2101 tcctacgcac tagcagatgg tgagcatttt attgttgatc cagataagtt atcttctaca
     2161 atggtagacc ttgaaaagat tttaaaacta atcgaaggtt tagattattc tacattacgt
     2221 cagactactc aaactcagtt tagagacatg actactgcag gtaaagcgtt gttgtcaaaa
     2281 tctaacctcc gacaaggaga aaaacaaaaa ttccttcaag aagcacaatt tttccttggc
     2341 cgcgttgatt tggataaagc catagctaaa gctgagaagg ctttagtgac caagaaggca
     2401 acaaagaatg gtcagttgct tgaaagaagc attaataaag cggtattagc ttataataat
     2461 agcgctatta aaaaagctaa tgttaagcgc ttggaaaaag agttagactt gctaacagga
     2521 ttagttgagg gaaaaggacc attagcgcaa gctacaatgg tacaaggagt ttatttatta
     2581 aagacgcctt tgccattgcc agagtattat atcggattga acgtttattt tgacaagtct
     2641 ggaaaattga tttatgcact tgatatgagt gatactattg gcgagggaca aaaagacgct
     2701 tatggtaatc ctatattaaa tgttgacgag gataatgaag gttatcatgc cttggcagtt
     2761 gccactttag ctgattatga ggggctcgac atcaaaacaa ttttaaatag taagcttagt
     2821 caattaacat ctattcgtca ggtaccgact gcagcctatc atagagccgg tattttccaa
     2881 gctatccaaa atgcagcggc agaagcagaa cagttattgc ctaaaccagg tacgcactct
     2941 gagaagtcaa gctcaagtga atctgctaac tctaaagata gaggattgca atcacaccca
     3001 aaaacgaata gaggacgaca ctctgcaata ttgcctagga cagggtcaaa aggcagcttt
     3061 gtctatggaa tcttaggtta cactagcgtt gctttactgt cactaataac tgctataaaa
     3121 aagaaaaaat attaaattga tttaaggaga aaaaatgata acacaagaaa tgaaagatct
     3181 tattaataac caattagcaa tggttgcgac ggttgatgcc aaaggtcaac ccaatattgg
     3241 tccaaaacgt tctatgcgtc tctgggatga taaaacattt atttataatg aaaatacaga
     3301 tggtcaaact cgtattaaca ttgaagataa tgggaaaatt gaaattgcct ttgttgatcg
     3361 tgagcgcctt ttaggttaca ggtttgtagg aactgctgaa attcaaacag aaggtgctta
     3421 ttacgaagca gcgaaaaaat gggcacaagg acgcatgggg gtaccaaaag cagttggtat
     3481 tattcatgtc gagcgtattt ttaatttaca atctggtgct aatgcaggta aagaaataaa
     3541 cagtgaaagt aactaaaatt aactgtaaca gtatttagga ctcttatttt aaacgctaaa
     3601 aaataagcat acttcttttt tacagcatag tgactatgtt gtaaaaaggg gtatgcttat
     3661 taggtgctct taatatttct agataactgc acctaataag ttttcaatag acttatagca
     3721 cattaattga cttcaatact agaaagagaa gaacagtgat gttggtgttc gtttaaagaa
     3781 gtatcgattt ccacagtgac tgagtttata ttgtaccttt gacaaatcag tctaatagat
     3841 tttttgcaat gtttttcagt ggtagattct ctcaagcagc aatgtatagt tgctctatga
     3901 tcaataccat ccatcgacca aacattaagc tgattaacag acactatatg aggaagttgg
     3961 ctgagttcct ggtgcaaagt gcaatagtct atcgaatcag gaacaccatc taaaaaaatg
     4021 ttagcagttg ctactaactt tggaagagct ttagataata taaaagaagc aatggcaatt
     4081 gataacaaag gatcaagaat gtaccaaggt ttccatttta agatcagtga cagtatgata
     4141 atggctaacc acccaaggat atcttctaaa aagtgaaggc ttaatatttc ttcatttttt
     4201 gtctggttag agtgaatgat gaagctagca aatccattga ttataattgc aaaaatagct
     4261 aaaacgaaca taccgtcata attaacaata gtaggatgcc ataattttgg tatcgtttca
     4321 atcattacta ataatgaccc gctaataagt attagatttg tcgttagtgc tcctaaaagg
     4381 ctaaatcgct tatagcctag tgaaaaattt ggactctctt ttttaacagc ctttctttct
     4441 aagatagctg agataccaat agcaatggca tctccaaaat cgtggacagc atctgctaaa
     4501 atagcacctg aaaagaataa tgttccaaaa ataaattcaa tgagggaaaa actaagattt
     4561 aatataaaaa taatggtgac ttttttactt gctggcataa ttttctcctt ttgtta
//
LOCUS       DAUGSW010000065         4529 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUGSW010000065 DAUGSW010000000
VERSION     DAUGSW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4529
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.065"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..1181)
                     /locus_tag="VIB18_001558"
     CDS             complement(<1..1181)
                     /locus_tag="VIB18_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEQ8766545.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNIAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     G"
     gene            1271..2137
                     /locus_tag="VIB18_001559"
     CDS             1271..2137
                     /locus_tag="VIB18_001559"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEQ8766546.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQNPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            2115..2672
                     /locus_tag="VIB18_001560"
     CDS             2115..2672
                     /locus_tag="VIB18_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8766547.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGAQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            2806..4350
                     /locus_tag="VIB18_001561"
     CDS             2806..4350
                     /locus_tag="VIB18_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8766548.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKSKPNFEFKQSRTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
BASE COUNT         1471 a          675 c          876 g         1507 t
ORIGIN      
        1 tttccagtta ttattattct atcagattta tctaatgtaa agtttctata agagtctgat
       61 gtcgtgtaat caatcactaa atgagtaggg gttagttgat agtgaatatc agggcaattt
      121 tgttttaaaa agagagccaa ttgacgttcc cgctgtttta gataacgctt aataaagcga
      181 agattttttt gaaacatccc attttctaaa taaagagcta atgctttttg cattagtaag
      241 ttcgtgtcta aatcaatcag tgatttttgg gttaaaaaat gaggttttaa acctgacggt
      301 aaaactagag ctccgatacg gagtgcagga aaaacactca ttgaaaaaga ttttaggtag
      361 atgattcggt gatgagtgtc ataataatga attggtggct ctttaagttt cacaaaatct
      421 cctaaataat catcttctaa aatataaacc tggtatcgtt gtgctagacg aacaatagct
      481 tccttttcct tagtgctata agaaagtccc agaggatgtg aaaatcgtga aatcgtgtaa
      541 aaaaatttaa tatcaccagt ttgaaataaa gattctaaga gttctaaatc aaggccatta
      601 aagtgtctag agatagtttg atagggtaat cctaactgag caacaatagc ttccatccga
      661 tgataagtag gcttttcaag gagaattgtt ttgcccgcat taggaaaagg catttgtgat
      721 aaaatataaa gcgcttgctg cgtcccagag gtgattaata gttggtcttt gttactgtaa
      781 acactatttt cagctaagta aagaagcaaa gcttccctta gttcttctag tccttcggtt
      841 ttgtgataat aatgaaagag gtatttgtct ttagcactta aagcctcatt taagcagagt
      901 cggaaatctt cataagctat attattataa tcttcaagac ttagattaag aacattatcg
      961 ggcatgctta cgttacccaa aacataataa ccacttttag gaacagcata aattaagtga
     1021 cgatatttta attctaaaag agcccgctga acagtatctt tgctacaatg ataaacctta
     1081 cttagtaccc taattgaagg tagcttgtcc ccttttttta gtcgctgttt ctggatatct
     1141 tgttcgatat tggaaatgat tgtttgatat tttgttgtca taaattgtcc ccatacagtt
     1201 aagtgttata actattgtat cttatgcctc tttttcttac aatggttatt atagaaaaga
     1261 ggtaatagct atgaaacgga ttattgtggc aaatgatctg gttggtgttg gtaaggtagc
     1321 tttgtctgct agtattcctt taatggcttc ttgtttgtta gagcaagttt tattaccaac
     1381 ttgcctttta tcaagccata ctggcggagg acagaaccct gtgaagcata ctacatcaag
     1441 tatattagac gtttttttaa cagattggga caacaaaaga attaagtttg acggcatctt
     1501 tataggttat tttacgacaa caagagatgg gcaaaagctg ctagaatggc tttcaagaaa
     1561 gcaacttccc ttaattttag atccaattat ggcagataat ggaaaacttt atcaaggctt
     1621 cagtcaaaaa catatagaga ttatgataaa acttactcaa aaagctgagc ttgttttacc
     1681 taatattagt gaggcttgtc tattaacaca aacagcttat ttagcaaaaa attatgatga
     1741 agaagatatt agacaggtgg ctagaaaatt agctaagctt ggacctaaac aggttgtcat
     1801 tagcggaatc tcttttgagg agggcagcat tggttttgct tactatcagt cagattcaga
     1861 tcaattaaca ttccattttg ggaagcaatt cccttaccat ttctatggta caggagatat
     1921 agcatcagct attataacag caggattcta ttatcagcta ccactaacac aaattctaga
     1981 tcttgttgtt tcatttcttg aaaaagtatt gcaaaatacc cttacattaa aaagagattt
     2041 aatcttaggt gttgcttatg aatctcattt aaattactta actaaatcgt ttaaaaagtt
     2101 gttggaggaa aaaaatgtca tctcaaaaat tagctaatta tattgaattg agtatgtatg
     2161 ccgctttaat ttttatttca gtacaagtat tgcgtatccc tgtcggtatg cagtttattc
     2221 atcttggcaa tgcattagtt gttattgcag tcttaatcta tggtagtaaa aaaggagctc
     2281 tagttgctag tcttggttta gggatctttg atgttttgaa cggctatgct tcagtcgttt
     2341 ggataactat cttagaatcc ttggctattt gtttaatttt gcatttggta tatgaaagag
     2401 ctatgcaatc tagtaaaaaa ccaaaagcca ttataacaat aacagttatt gctgcattgt
     2461 caaaattaac tattaacctt ataaaatact tactgttagc ttatataggt gctcagctac
     2521 cactttcggt atctttttgg gtagctcttg gaaaaattgg tggtagtttc ggaacatctt
     2581 ttgtgacttt agttgctgtt cctcttttgt atcctgttat caaaaactta aaagaaaagg
     2641 ttacaatcgg acaagcaaaa agaggttttt gatacaagta ccttatcgat aaaaaagcaa
     2701 ggtacacttt tagtcaaata ttgacaaaag gttacaattt tgccataatg aaataactat
     2761 aaagccgttt tgacggcttt tttgatgaca gttaaggaag aaacgatgag tattttagaa
     2821 gttaagcagt tgagtcacgg ttttggggat cgggctattt ttgaaaatgt gtcatttcgc
     2881 ctcttaaaag gtgaacatat tggactagtt ggagcaaatg gtgaaggaaa atcaaccttt
     2941 atgagtatag tcacaggaca tttacagcct gatgaaggaa aagtagagtg gtcgaagtat
     3001 gtcactgcag gttacctgga tcaacataca gtgttggaat caggacaaac cgttcgtgat
     3061 gtcttgcgaa ctgcttttga tgagttattt aagaccgaga atcgtattaa tgagatttac
     3121 gcgtcaatgg cagatgataa agctgatatt gctgttttga tggaagaagt aggtgagctt
     3181 caagatcgtt tagaaagtcg tgatttctat actttggatg ctaagattga tgaagtagcg
     3241 cgtgcgcttg gtgttatgga ttttggaatg gagtcagatg ttacatcctt atcaggtggg
     3301 caacgaacaa aggttttatt agccaaatta ctattagaaa aacctgatat tctgctatta
     3361 gatgaaccaa ctaaccattt ggatgctgag catattgaat ggttaaaacg ctatttacaa
     3421 cattatgaaa atgcttttgt gttgatttcg catgatattt ctttcttaaa tgatgtgatt
     3481 aatattgttt atcatgttga aaatcaaagt ttagttcgct atactgggga ttattaccaa
     3541 tttcaagctg tttatgagat gaaacaatct caacttgaag cagcctatga acgtcaacaa
     3601 aaagagattg ctaacttgca ggattttgtc aaccgaaata aggctcgggt agcgacacgt
     3661 aacatggcaa tgtctcgcca aaaaaaactt gataagatgg atataattga acttcaagct
     3721 gagaaatcaa aaccaaattt tgaatttaag caatctagaa ctcccagtcg attcattttt
     3781 caaacgaaaa atcttgtgat tggttatgat tacccattga ccaaagaacc tttaaatata
     3841 acgtttgaaa gaaaccaaaa aattgctatt gttggggcca acggtattgg aaaatctact
     3901 ttgctaaaaa gtttattagg tgttattgag cctttagaag gtcatattgt cacaggggat
     3961 tttttagaag ttggctactt tgaacaagaa gtgacaggtg ttaaccgaca aactccgcta
     4021 gaagtagttt gggatgcttt tcctgcctta aatcaggcag aagttcgagc ggcactagct
     4081 cgttgcggac taacatcaaa acatatcgaa agtcaaattc aagtactttc gggtggtgaa
     4141 caagcaaaag ttcgtttttg tttgttgatg aatcgtgaaa ataacgtgct tattttagac
     4201 gaaccaacaa atcatcttga tattgatgct aaaaatgagc tcaaacgtgc tttaaaagca
     4261 tataagggtt ctattttaat ggtttgtcat gaacctgatt tctacaatgg gtgggtaacc
     4321 gatacttggg attttagtaa gttaacctaa actattcctt aattttttac atagaaatta
     4381 ctaaaatcag taaagatata gaataaatac tgctagatat gtgatggttt aggtaactga
     4441 tcaccaacca aaaaaaagat gtgactacat ctttttttta tctaatggaa tggtgtaaag
     4501 tcgtttaata atagcttatt ttttgatga
//
LOCUS       DAUGSW010000066         4161 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUGSW010000066 DAUGSW010000000
VERSION     DAUGSW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4161
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.066"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(97..460)
                     /locus_tag="VIB18_001562"
                     /pseudo
     CDS             complement(97..460)
                     /locus_tag="VIB18_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(881..1414)
                     /locus_tag="VIB18_001563"
     CDS             complement(881..1414)
                     /locus_tag="VIB18_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEQ8766549.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1494..2270)
                     /gene="recX"
                     /locus_tag="VIB18_001564"
     CDS             complement(1494..2270)
                     /gene="recX"
                     /locus_tag="VIB18_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEQ8766550.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDSYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2385..3740
                     /gene="rlmD"
                     /locus_tag="VIB18_001565"
     CDS             2385..3740
                     /gene="rlmD"
                     /locus_tag="VIB18_001565"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8766551.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAVIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
BASE COUNT         1238 a          679 c          882 g         1362 t
ORIGIN      
        1 cattataaaa gaaattgttt aattaatgga tagtaatgga tggtatggag atcttaatgt
       61 ggttttaatg gtaattttag cagttatagt aagacaaaag gtgacttgga aaagcttatg
      121 cagacgattc ttaactccca caatatcttc tgtcagattt tattagactt cttctcagtg
      181 tcaattttgt ctgttttacg aacgtgcagg ctattcaatt gcttcttagc ttctaaagga
      241 ttaaaccgag tataagcgta gccattatct gcgaaaaaac ctgaagacga cgagaataga
      301 cattaatcgt tttaagggta atctcagggt tatggacggt tttcaagttt ccaagaagat
      361 gattgaggcc gatggtatcg ttttgtcttg aatgattcct tattttagtg gtttcatttt
      421 caatacacga cgtcaagcgt cctacatact ttgataaaat tctacctaaa agaggtgtct
      481 tgtcagtttt ggttacaaca tcaagtgcta aaagactttg cgacttaaca agacacttct
      541 actttaacgc aaagaaaaag tagtgagtac tctctttcgt cggagatttc ctcgctacta
      601 aacttagtat tttttgatac tttccttagg tagtgcttaa ggcagcgact ttctttggaa
      661 ttccatacct tatttttgag atcctaggct caaaaatgcc aagtggcgtc aacattaaca
      721 ttgacaccac ttttaccaca acgaaaaaca tctgttttgg ctcactccac acgcagaaat
      781 aggaaattgg atgtcaaatc agcagagctg ttcatgcttt ttgagcctaa aactgagttt
      841 gtctgcgttc tgagcactcc ttgggagtgc tggacaactc ttaacgattc ttcagttcaa
      901 gataacgttt gtaccaaata gtgatatagg ccttggaaaa tggtcctttt tcatgattaa
      961 tccaatcaac caatattttg acattttctt ttaggataaa gtccatatcg gctgaatact
     1021 gcatctcttt tttatgaatc tcgtattcat caacatcaag taatctcttt tcaccatccg
     1081 caaagacttt gacatctaaa tcgtaatcaa tgtatttaag ggcctcagtg tccatcatgt
     1141 atggactagc taagttacag taataagaga cgccattatc tcgaatcatg gctataatgt
     1201 taaaccagta ttttttatga aagtaaacga ttgcaggttc gcgggtcacc catcgtctac
     1261 cgtcactttc tgtgacaaga gtgtgatcat taactccaat gagggcattt tcagttgttt
     1321 ttagtaccat agtatcgcgc caagtacggt gcaaactacc atcatgctta taactttgaa
     1381 ttgtaataaa gtcgccttct ttaggtaatt tcatgcctta ccaactttct acaattaaac
     1441 ttatcctcta tagtctatca taaatgtgtg aaaaaatcac ttcttttgtc agtctataaa
     1501 taatttctta acttgcaatt aatatcgtcg ctgttgtagc cttttcggta gagagcctga
     1561 tagagctttt gctttaaggt ataactatca tatttgcgac tgagtttacg atattgtttg
     1621 tctaattctt tgtcaagaag atcttctatt tcttgattat cttggtcaaa attaaggtga
     1681 ttgaggctat gtttagctag atcgtatgaa aagcctttag tcagtaatgc ttgggtgatt
     1741 ttatctttca aggcttttgg tggcaatttt tcttgatatt tgtcaaagag tttttggctt
     1801 actttttgag cgagttggct aaagtcagtt tgagataaga taggatcaat gtcatgactt
     1861 gcaatgcctt tttgtaataa tttttgtttt aagacttggg gacctttatc accatttaac
     1921 tgattttggc gaatgtaggt atcagccaat ttggtgtcgt ctatccattg ttcttcttgg
     1981 agttgagtga tgatgtcagc aataatgtgt tcttcaatct catgcttgcg caggtaatca
     2041 gcaacttgct tgttgctgcg ttgttgaaag gaaagaaaat aaagggctaa atttttgccg
     2101 taggacagtt gggcaaaatg tttcatgtct tcaagctgat cattgtcaag gactttatct
     2161 ttactcaaca taaaccgaac aatagtatct tctgttacat aaagggattc gtcattatcc
     2221 aattcgataa ggtagaggcg ttttttcttt tcaattttag tgattttcat actttgatta
     2281 tatcaaaaat ggtaaaatag aagacgaaaa tactgctaaa aatgtgttgc ttgtgaatgc
     2341 ttttggtggt gagattagga tactagagga agtaagggga agagatggtc gtaaaggtta
     2401 aacagaaaat tcctttaaaa attaagcgaa tgggaattaa cggtgagggg attggttttt
     2461 atcagaaaac tttggtattt gtccctggtg ctttaaaggg agaagatatt ttttgccaaa
     2521 tcacggcggt taaacggaat tttgcagagg ccaaactgtt aacggtaaac aaggcttcta
     2581 agaatcgtgt caaaccagct tgttctgttt atgaaacttg tggtggttgc caaatcatgc
     2641 atctagccta tcctaaacag ctagatttca aagatgatgt gattaggcag gcccttaaaa
     2701 agttcaaacc aactggctat gaacaatttg agattagacc gactttagga atgaaaaagc
     2761 cagatcacta tcgggccaaa ttgcagtttc agctgcggtc atttggcggg acggtcaagg
     2821 ctggtttatt ttcccaggga agtcatcgct tggttcctat tgacaattgc ttggtacagg
     2881 atcaactaac gcaagatatt atcaataaga ttacgcagtt agtggacaag tacaagttgc
     2941 ccatttacaa tgagcgcaag attgctggga ttcggacgat aatggttcgt aaggcacagg
     3001 ctagtgatca ggtacagatt attgttgtga gtagcaaaga agttaggtta gcgaatttca
     3061 ttggcgaatt gactaaggca tttcctcagg ttaaaacggt tgccttgaat agtaatcgtt
     3121 ctaaatcgag tgagatttat ggggacgaaa cggaaattct atggggacaa gaggcgattc
     3181 atgaagaagt tttagactat ggatttgcgt tatcaccgag agctttttac caacttaatc
     3241 cacagcagac agaagttttg tatggtgagg tggtgaaggc cttggatgta gggagcaaag
     3301 atcatattat tgatgcctat tgtggggttg gctcgattgg ctttgctttt gcagggaagg
     3361 tcaagtctgt gcgggggatg gatattatcc cagaagcgat tgaggatgca caaaaaaatg
     3421 ccaaagccat gggctttgac aacgcttact atgaggcagg gaaggcagag gatattattc
     3481 ctaaatggta taaacaaggt taccgcgcgg atgccgtcat tgtggaccca ccaagaactg
     3541 gtttagatga taaattatta aaaacgattc ttcattacca gcctaaacag atggtttatg
     3601 tgtcttgtaa tacctccact ttggcccgcg acttggtgca gctaacaaag gtttacgatg
     3661 ttcactatat ccaaagtgta gacatgttcc cccatacagc taggaccgag gctgtcgtga
     3721 agttacaaaa acgtgtatga ttgagtggca ataacaactc aagttttata agctcaggta
     3781 atgggtttga gcaatagctt gacatagtag ggatgtcaaa aacggtttac taagcatagt
     3841 catattattg ataactctat gtttatttta gaaacattca tggttaaaaa agtttgttag
     3901 tttgccacta agtagggtct atttgaagag taagtacaca cagacaatat tgggtaattg
     3961 attgttgaaa aatagctgtt ttttgctata aattagaaaa ctgagtggtc aggaggttac
     4021 attaccagaa gttattttag tatgctaata tgaacgatga tatagaggat ttatcctgat
     4081 ttaatctttt aagctgtaag aaacctttgc aaaaactgta ggctgtgtga gtctttatgt
     4141 gttagatatt aaagataaaa a
//
LOCUS       DAUGSW010000067         4111 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUGSW010000067 DAUGSW010000000
VERSION     DAUGSW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4111
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.067"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     misc_feature    53..188
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            217..717
                     /locus_tag="VIB18_001566"
     CDS             217..717
                     /locus_tag="VIB18_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEQ8766552.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            782..1147
                     /gene="rplL"
                     /locus_tag="VIB18_001567"
     CDS             782..1147
                     /gene="rplL"
                     /locus_tag="VIB18_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEQ8766553.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            1406..2005
                     /locus_tag="VIB18_001568"
                     /pseudo
     CDS             1406..2005
                     /locus_tag="VIB18_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            2180..2505
                     /locus_tag="VIB18_001569"
                     /pseudo
     CDS             2180..2505
                     /locus_tag="VIB18_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            2496..2770
                     /locus_tag="VIB18_001570"
                     /pseudo
     CDS             2496..2770
                     /locus_tag="VIB18_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2816..3090
                     /locus_tag="VIB18_001571"
                     /pseudo
     CDS             2816..3090
                     /locus_tag="VIB18_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3294..3991
                     /locus_tag="VIB18_001572"
                     /pseudo
     CDS             3294..3991
                     /locus_tag="VIB18_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
BASE COUNT         1418 a          636 c          868 g         1189 t
ORIGIN      
        1 tttttaataa tttttattga caatagtatt ataaaagaat ataatgatat aggttttgat
       61 aaaaaactga cctaagacag caggggagca tgctcataat attcctgccg aggcacaaaa
      121 cgtgattaaa gaaaataacg tatttgtact ttcgtgtcta ggtttaggtg cgattttttt
      181 gtacctagcc caaaaataaa aacggaggta aaactaatga gtgaagcaat tattgctaaa
      241 aaagctgaac aagtcgaact tattgctgag aaaatgaaag cagcagcaag tatcgttgtt
      301 gttgattcac gtggtcttac agttgatcaa gatactgttc ttcgtcgttc acttcgtgaa
      361 agtggcgttg agttcaaagt tatcaaaaac tcaattttga ctcgtgcagc tgaaaaagca
      421 ggtcttgatg agttgaaaga tgtattcgta ggaccatctg cagtagcatt ttctaacgaa
      481 gatgttatcg caccagctaa agttatcaac gactttacta aaactgctga cgcacttgaa
      541 atcaaaggtg gtgcaatcga aggcgctgtt tcttcaaaag aagaaatcca agcacttgca
      601 acattgccaa accgcgaggg aatgctttct atgcttcttt ctgtacttca agctccagtc
      661 cgcaacgttg catacgctgt caaagctgtt gcagaaaaca aagaaggcgc tgcttaagac
      721 gtctcagagt agcttaaggc tacgcttaac attttaaatt aattatttgg aggaaatcac
      781 aatggcattg aacattgaaa acattattgc tgaaattaaa gaagcttcaa tccttgagct
      841 taacgatctt gtaaaagcta tcgaagaaga atttggtgta actgcagctg ctcctgtagc
      901 tgctgcagct gctggtggtg ctgaagaagc tgctaaagat tcattcgacg ttgaattgac
      961 atctgctggt gacaaaaaag ttggcgttat caaagctgtt cgtgaaatca caggtcttgg
     1021 tcttaaagaa gctaaaggtc ttgttgatgg agcacctgct aacgttaaag aaggcgttgc
     1081 tgctgcagaa gctgaagaaa tcaaagctaa acttgaagaa gctggagcaa caatcactct
     1141 taaataagaa gcagatagca atttgagagc gaaatcccga tttatcagtc ttttagagct
     1201 tatagcgatt tgaagaaact gataaaatga tttggttttt tgccaaaaat cctgccaaaa
     1261 aaatctttgg caggattttt attttctata aaaattaagc tgagtagagt ggttattcta
     1321 tctatatgtg tctagtaata atttttttat tttcaggagg aaaatcatgc aaatgaatga
     1381 acagtcatca cgacaaatgg tgattgccat ctatctcatt tattccaact caaaatgata
     1441 gtactccttg gctgttccaa gtcgaaattg ttagtgatta agaaaaccta cgagactatg
     1501 gtttgatcga tgaaggccag cagtctccca gtgaaaaagg gcgtttggct aataagattt
     1561 atttaggaaa gttggaacat gatttcaccc cagtcttaag ttcagacggg gccagtctca
     1621 aaaacagacc agccccgtgt taaattcagc ccctagtgag actgaaaaga gtgaaactga
     1681 aggtagtgaa actaaagaga gtaatttagt cattgaggac gaggaggaaa gaaaggagtg
     1741 cactagtgtg aaaaagactg agggtcactt tactcgtcaa gttgatcatg tcaccaaata
     1801 tgacaaagat tatatttgga gtttggttca ttcccaatta cgtgaaggtg gtttatcaca
     1861 agctgctagt gacttagtca tgagctattt tgaagaacgc tatgcttatg cgctggaaca
     1921 catacggttc gcaagaacag ctgaagctat tgcggaatat gtctttaatg gtgtcttatc
     1981 cgaatggacc aagcaactaa ggtgacaaga agcgaagtga gtaagatgtt ttggtggcta
     2041 ttattaggtg tttggggact aaggacaatt tggttgatta ttgaagttat cactgcacca
     2101 gaaatggaag attatagttg agtaaggacg ttacataagc agtaaggtcc ttttattttg
     2161 tcagaaagga atgagagata tgcagttttt agatttgttt gcaggaattg gaggctttcg
     2221 attgggttta attaatcagt gccatgagtg tattggcttt tgtgagattg ataagtttgc
     2281 gaggcaatct tacaaagcca tctatgagac cgaaggagaa atagaatttc atgacattag
     2341 acaagtcaca gaccaagact ttagacaact tagagggcaa gtggatatca tctgcggtgg
     2401 tttttccctt gtcaagcatt ttcactcgca ggcagacgac tgggatttga gggcactagg
     2461 agaactcttt tctttgagat tactcgagcg accaaacaga taaaaatcat acccataatc
     2521 acatccaatc aacgccattg accgtaattc agataaaaaa ttgatatgga attatgcctt
     2581 ggaacgaaac ctccgtatga tttcagaccg tatttcaaaa atgactggag caaaaattat
     2641 cgagaagcgt tattcctacc gtgactatca aaaatatagg cagtctagtc ataaatttga
     2701 attgaaacaa cgtctttatt ttttgatgca gcagtcaaag ttctttgatg attttttaga
     2761 aaaagcagag taattacatg ttcatattga ttttagtcag aagcatagca gattcatgat
     2821 gacggatcga gtaatgaaaa aaccaattcg aggccgtcaa ctcagtaaac gagatttata
     2881 tgatgaagaa ttttttcgta cacattttgc caagatagaa attgaaagtc gattagaatt
     2941 tttgttgaac cgtgccaatt cattagagga gctactatta aaagcaaaag aagtgaatct
     3001 aaccattgac ttaaaacaaa aaatgtaact tttatcctag aagaagatac tcaaaagata
     3061 agtttaggtc ataaaaaaaa taagcgataa gaaattatat gatgtcaatt ttttcaagat
     3121 tactttaaaa ataaggaaat cggtgtttca gatcgattag aaagtctaca gaaacagtac
     3181 atgcttttca agaagaacga gataaagagg aggtatccac tgaagagagt aaggaagtct
     3241 tcaagaaata caaggggcaa cgagatgcca tccatgagtt tgaagttgaa cttgtggaac
     3301 atcaaattga gaggttaatt gctgaggaca tttatatcaa ggtgtctttt ggtgtaaagc
     3361 agagtggtct tattttcatt cctaactatc aattggatat taggaaagaa gaaaatcata
     3421 aaaaatataa agtctatatt cgtgagaccg cacaattctt catttacaac aaggaggcgt
     3481 ctaaacttaa tcgctatatg cgagggcgtg agctcattta ccagttaacc aatgatagca
     3541 agagtattcc aaaaagaaga cgaccaaaac cattgataca cttaagaaaa agattgaaga
     3601 aataagtctc ctcattgagt tagatatgga gaataagcct tatcaagata ttaaagatga
     3661 cattgttaaa gatatggctc aattagattt gaccattaca gagttgcagg accatattgc
     3721 tcatctcaat aaggttgcgg aggtcttgct taatctgaac aacaacgata tagagaacca
     3781 ccgtttggcc agatatgact atgccaagat gaacttgact gcagctataa aaatagaaga
     3841 agttgagaaa gagattgaaa cttctcaaaa tgaacttaat atatccatag atgagtatga
     3901 atatctagta agaaggttgg aaaagtttgg agagatcttg agtgatagca aaattatcga
     3961 tacttctcga aatgaaatac aatgggagta attatgatat aatttgggtg gtagcaattt
     4021 ttatatcaga tattaaaatc tagttgatgt ttcgtaaata actatattaa agaaatgatt
     4081 cctgccgctt acattgagaa tagtttattt g
//
LOCUS       DAUGSW010000068         3825 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUGSW010000068 DAUGSW010000000
VERSION     DAUGSW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3825
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.068"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            21..821
                     /locus_tag="VIB18_001573"
     CDS             21..821
                     /locus_tag="VIB18_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEQ8766554.1"
                     /translation="MGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQS
                     EARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLS
                     DVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFDGTLHFIPNRSITVVS
                     NKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQ
                     FTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS"
     gene            complement(886..1446)
                     /locus_tag="VIB18_001574"
     CDS             complement(886..1446)
                     /locus_tag="VIB18_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEQ8766555.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(1460..1930)
                     /locus_tag="VIB18_001575"
     CDS             complement(1460..1930)
                     /locus_tag="VIB18_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8766556.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWFGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILKQKKR"
     gene            complement(1920..2684)
                     /locus_tag="VIB18_001576"
     CDS             complement(1920..2684)
                     /locus_tag="VIB18_001576"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEQ8766557.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHVGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            complement(2674..3423)
                     /gene="truA"
                     /locus_tag="VIB18_001577"
     CDS             complement(2674..3423)
                     /gene="truA"
                     /locus_tag="VIB18_001577"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEQ8766558.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQDAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            complement(3610..>3825)
                     /locus_tag="VIB18_001578"
     CDS             complement(3610..>3825)
                     /locus_tag="VIB18_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ8766559.1"
                     /translation="EIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQAL
                     IRGERFKGRRALLRKISPYFKEFAQQL"
BASE COUNT         1221 a          846 c          565 g         1193 t
ORIGIN      
        1 agcagtctca tatcgaaaat attggcttaa cgatttttaa aaagctagtg tctctcatta
       61 ttctattact cttttttgct attttaaaac gtgttactaa ctatcttttt gaaaaaacca
      121 ttaacaaatc gtttgcttat tcaagacaaa gtgaagctcg caaaaaaaca ctctctaagc
      181 tcactcacaa cattttaaat tacttattgt attttcttct catttattgg atacttagct
      241 tatttggcat acctgtctct agtcttctag caggagctgg aattgctgga gtagcaatcg
      301 ggttaggtgc acagggattt ttatctgacg ttgtcaatgg cttttttatc ttatttgaga
      361 atcaatttga agtaggagat aacgttacta tctctgacat agaaggcagt gtctttggtg
      421 ttggaattag aactactcaa attcgtggat tcgatggaac actacatttc atcccaaacc
      481 gtagcatcac cgttgtcagc aacaaatctc gtggtaatat gcgtgcctta attgaaattc
      541 ctctttattc cactgttaat ttgagccaag tcactcgaat cattgatgaa gtgaatcaaa
      601 aggaattgcc aaaccatcct caaatcgttg gcaaaccaaa tattttaggg cctcaaaata
      661 actctaatgg acagttcact tttagaattg ctattttcac agaaaatgga gaacaattta
      721 agatttacca tactttttat agactttatc aagaagcttt actcaaagaa ggcattcaat
      781 taccgactgc aatcagctat tctatcacct caaaatctta atataatctt aaaaaatcct
      841 tttttctaga aaaaacacca attgttttat tccagaaaaa agggtttagg atttacggat
      901 aatatccata ttgtaatcag ccctagctcc accaattaat tttggtcgac tagccaaagc
      961 tgtcacatga gcacctccta gctctcgttg acaaggaatc agagggatct gaacacgctt
     1021 aatatgcatt cctatagcag tatcacctat atcaagtcca gcgtgtgcaa taacttcttc
     1081 tacttcgaca gggtctgaca taagttgaaa agcagccatc tgagcactgc caccagcatg
     1141 aagattcgga accacattga caatctctaa ctgcttagat tctgccacat gcctctctac
     1201 taccaaggca cgattgacgt gttcacaacc ttgtacagcc aaatgaacac cacgcttatt
     1261 taactcatct aacacaactt caacaactat ttgacctact tctagactag attgttttcc
     1321 aattctacta cccaaaattt cgctagatga aagacctaga acaaaaagat tacctggttg
     1381 aatagcagag cgttctacaa catcaataac gatttccctt gtttgtttct ctaaattatt
     1441 caacaacttc tcactctcct tatctctttt tttgctttaa tatggcctta aagataataa
     1501 aaccaacaaa aagtcctaat gtattttgca tgacgtttcc ccaaataccg gctaaagatc
     1561 ccgaaaggcc ataaccaagc ataagagagc ctaaaaaata ccaaaaaatc atgataaaag
     1621 aacctatcac aacaccaaac caacgcttgc gtcctctcca tcccgcaaaa tacccttgga
     1681 cactgtgagc aatcaaacta tgaaacatcc actgagggta tcctgccact aaatcaatta
     1741 aaaaacctga taaccctccc acaatagctc cttgagctga tccaaaggaa aagctgacag
     1801 cataaatgcc tgcatccaac agcgttaaaa aacctgttgg agtaggtagc atgacaaatc
     1861 ttcctaaaac aacaaccaat gctgtcaata tccctgttaa actcatttgt cgtatcttac
     1921 tattttgcat aactttgttt tactccgtat ctatcagatt gtaaaatagc ttggtagact
     1981 aactcttttg agtttttcac agcttctagt ggcgtttttt tctttactaa ctgactagcg
     2041 atactagatg caaaagtaca gcctgcgcca atattatttt tctcaagtac aggacattcc
     2101 aaggtaacaa tctctttacc gtcataaaaa agatcaatag cctttttctg actaaatcga
     2161 ttaccaccct tgataaccac ctgttttgcc ccaagttgat aaaaatattt agcagcttct
     2221 tgcatatctt ttaaagaaac aatctctttt tgagataata gctgagcctc taccaaattt
     2281 ggagtaacaa cagtcacata aggcaataat tgtaaaatct cctgtcttag aggaactatt
     2341 ttaacatcat ctatttcttt acatgctaga acaggatcta aaaccactgg gattcccaca
     2401 tgccccttta taaaatccaa aactatttca cacatttccg cattaggtaa caaaccaatt
     2461 ttaatagcag aaattggagc gttcgtaaag ctgttcaact gatcacggaa aatttcttta
     2521 gctaccggaa atagactaaa gccctcttca gatctagtag ttaaacaagt taccgctaca
     2581 aaggcctgta ggtcatacct tatgtaagtc gctaaatcag catagaggcc acctccactt
     2641 aaaatatcgt tcccagatat agtcacgata taatcagttt tcataacaaa tctccttcaa
     2701 gtaaagccca tttccagata tcgttggtcc agctagctga cgatttttgg agctcaaaat
     2761 cactttaact tgttcaactg gcatttgacc attaccaatt ttcagcaaag ttcccaccat
     2821 attcctcacc tgcttataga gaaaaccatt tcctgaaaaa gtaaacacca aaaaatcagt
     2881 tttttcatcc cgagataccg ttgctttggt aatcgttcgc accttatttt gtaccgaagt
     2941 tcctgctgct gtaaaaccag taaaatcgtg tgtacctacc agaccgttaa tagcgtcttg
     3001 cataagttta atattaagag tataagggta atgagtggta tagtgtcgca tcatcggatt
     3061 tttaggtcga ccattatcaa ctaaaaattc ataagttttt aaatgcttct gataacgaca
     3121 gtgaaaatca tcagccactt tttctatatt aacaacatca atatcttcag gagtctgtgt
     3181 atcaagagca aatcgtaatt tttcaacttc ttgttcttga ggcaaatcaa aatggatcac
     3241 ctgtccataa gcatgtactc ctgcatccgt acgtcctgca ccatgaatta taatttttgt
     3301 accgttattt aatttataga gtgttttttc aatctcttct tgaaccgtac gtaaatgtct
     3361 ttgtctttga aaacccgaaa aaagagtccc atcataggaa atcgttgctt tgtatcttac
     3421 catgttacta ttttaacatt tcttaaacgt aagagaaact atttttaatc aaactgtacc
     3481 caaacaaatg aaagacgtat tgaagcttac tccaagctac taacgattta aaagctataa
     3541 gaaagctatt tcctccacac actctctcct tttttcatag atttatcccc aattccttat
     3601 aggtcttgct tacaactgct gtgcaaattc cttaaaatag ggactgatct tcctaagtag
     3661 agcacgtctt cccttgaaac gttcgcccct gataagtgct tgaaactgca tacgctcttg
     3721 cgaatttaat tggttctcta agctagctat tacctcttga taagccacat agtcgtctag
     3781 ccataaccct ctcgatggaa tggcatgtgc aacctcccct atctc
//
LOCUS       DAUGSW010000069         3678 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUGSW010000069 DAUGSW010000000
VERSION     DAUGSW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3678
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.069"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..1130
                     /gene="hasA"
                     /locus_tag="VIB18_001579"
     CDS             <1..1130
                     /gene="hasA"
                     /locus_tag="VIB18_001579"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HEQ8766560.1"
                     /translation="VIKLGLSFLYEPFKGNPHDYKVAAVIPSYNEDAESLLETLKSVL
                     AQTYPLSEIYIVDDGSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAF
                     ERSDADVFLTVDSDTYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRLTDIR
                     YDNAFGVERAAQSLTGNILVCSGPLSIYRREVIIPNLERYKNQTFLGLPVSIGDDRCL
                     TNYAIDLGRTVYQSTARCDTDVPFQLKSYLKQQNRWNKSFFRESIISVKKILSNPIVA
                     LWTIFEVVMFMMLIVAIGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMIKHPAS
                     FLLSPLYGILHLFVLQPLKLYSLCTIKNTEWGTRKKVTIFK"
     gene            1166..2374
                     /gene="hasB"
                     /locus_tag="VIB18_001580"
     CDS             1166..2374
                     /gene="hasB"
                     /locus_tag="VIB18_001580"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEQ8766561.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQVINVLEEQESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2556..3470
                     /gene="hasC"
                     /locus_tag="VIB18_001581"
     CDS             2556..3470
                     /gene="hasC"
                     /locus_tag="VIB18_001581"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEQ8766562.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQTPGSGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
BASE COUNT         1267 a          624 c          643 g         1144 t
ORIGIN      
        1 tagttattaa acttggatta tctttccttt atgagccatt taaaggaaat ccacatgact
       61 ataaagttgc tgctgtaatt ccttcttata atgaagatgc cgagtcatta ttagaaactc
      121 ttaaaagtgt gttagcacag acctatccgt tatcagaaat ttatattgtt gatgatggga
      181 gttcaaacac agatgcaata caattaattg aagagtatgt aaatagagaa gtggatattt
      241 gtcgaaacgt tatcgttcac cgttcccttg tcaataaagg aaaacgccat gctcaagcgt
      301 gggcatttga aagatctgac gctgacgttt ttttaaccgt agattcagat acttatatct
      361 atccaaatgc cttagaagaa ctcctaaaaa gcttcaatga tgagacagtt tatgctgcaa
      421 caggacattt gaatgctaga aacagacaaa ctaatctatt aacgcgactt acagatatcc
      481 gttacgataa tgcctttggg gtggagcgtg ctgctcaatc attaacaggt aatattttag
      541 tttgctcagg accattgagt atttatcgac gtgaagtgat tatccctaac ttagagcgct
      601 ataaaaatca aacattccta ggtttacctg ttagcattgg ggatgaccga tgtttaacaa
      661 attatgctat tgatttagga cgcactgtct accaatcaac agctagatgt gatactgatg
      721 tacctttcca attaaaaagt tatttaaagc aacaaaatcg atggaataaa tcttttttta
      781 gagaatctat tatttctgtt aaaaaaattc tttctaatcc catcgttgcc ttatggacta
      841 ttttcgaagt cgttatgttt atgatgttga ttgtcgcaat tgggaatctt ttgtttaatc
      901 aagctattca attagacctt attaaacttt ttgccttttt atccatcatc tttatcgttg
      961 ctttatgtcg taatgttcat tatatgatca aacatcctgc tagttttttg ttatctcctc
     1021 tgtatggaat attacacttg tttgtcttac agcccctaaa actttattct ttatgcacca
     1081 ttaaaaatac ggaatgggga acacgtaaaa aggtcactat ttttaaataa tatgtgcatc
     1141 gagtagttag agaaggagta attttatgaa aatagcagtt gctggatcag gatatgttgg
     1201 attatcacta ggagttcttt tatcacttca aaacgaagtc actattgttg atattcttcc
     1261 ctctaaagtt gataagatta ataatggctt atcaccaatt caagatgaat atattgaata
     1321 ttacttaaaa agtaagcaat tatctattaa agcaacttta gatagcaaag cagcttataa
     1381 agaagcggaa ctggtcatta ttgccacacc tacaaattac aacagtagaa ttaattattt
     1441 tgatacacag catgttgaaa cagttatcaa agaggtacta agcgttaata gccatgcaac
     1501 tcttatcatc aaatcaacaa ttccaatagg tttcattact gaaatgagac agaaattcca
     1561 aactgatcgt attatcttca gccctgaatt tttaagagaa tctaaagctt tatatgacaa
     1621 cttatatcca agccgaatta ttgtttcttg tgaagaaaac gattctccaa aagtaaaggc
     1681 agacgcagaa aaatttgcac ttttattaaa gtctgcagct aaaaaaaata atgtaccagt
     1741 gcttattatg ggagcttcag aagctgaagc agtaaaacta tttgccaata cttatttagc
     1801 gttaagggta gcttatttta atgagttaga cacttacgca gaatcgagaa aattaaatag
     1861 tcacatgatt attcaaggta tttcttatga tgatcgaata ggaatgcatt ataataaccc
     1921 atcatttggt tatggaggtt attgtctacc taaagatacg aagcaattat tggcaaatta
     1981 caataatatt ccccaaacgc taattgaagc tatcgtttca tcaaataatg tgcgcaagtc
     2041 ctatattgct aagcaagtta tcaacgtctt agaagagcag gagtccccag taaaagtagt
     2101 cggggtttac cgtttaatta tgaaaagtaa ctcagataat tttagagaaa gtgctatcaa
     2161 agatgttatt gacattctta aaagtaaaga cattaagata attatttatg agccaatgtt
     2221 aaacaaactt gaatctgaag atcaatctgt acttgtaaat gatttagaga atttcaagaa
     2281 acaagcaaat attatcgtaa ctaatcgcta tgataatgaa ttacaagatg ttaaaaataa
     2341 agtttacagt agagatattt ttaatagaga ctagccatgt cttcatctat aacaataata
     2401 ttcattttta ctttaaaaga actgcagttg gtggtatgat tgagcactat gaaatagtcg
     2461 aaaaatcata tgaaaacgta acatgatgtc aaatgaattc cgttctgaaa acgaatgtca
     2521 ctaagccata gattataaaa agtgaggagt tactgatgac caaagtcaga aaagccatta
     2581 ttcctgctgc aggtctagga acacgttttt tacctgctac caaagctctt gccaaagaga
     2641 tgttgcccat cgttgataaa ccaaccatcc agtttatcgt cgaagaagcg ctaaaatctg
     2701 gcatcgagga aatccttgtg gtgaccggaa aagctaaacg ctctatcgag gaccattttg
     2761 attcaaactt tgaattagaa tacaacctcc aagctaaggg gaaaaatgaa ctgttgaaat
     2821 tagtggatga aaccactgcc attaaccttc attttatccg tcaaagccac ccaagaggac
     2881 tgggagatgc tgtcttacaa gccaaagcct ttgtgggcaa tgaacccttt gtggtcatgc
     2941 ttggagatga cttaatggac attacaaatg catccgctaa acctctcacc aaacaactca
     3001 tggaggacta tgacaagacg catgcatcca ctatcgctgt gatgaaagtt cctcatgaag
     3061 atgtgtctag ctatggggtt atcgctcctc aaggcaaggc tgtcaagggc ctttacagtg
     3121 tagacacctt tgttgaaaaa ccacaaccag aagatgcgcc tagtgatttg gctattattg
     3181 gtcgttacct cctaacccct gaaatttttg atattttgga aagacagacc cctggatcag
     3241 gtaacgaagt gcaactcaca gatgctatcg ataccctcaa taaaactcag cgtgtctttg
     3301 cacgagaatt taaaggcaat cgttacgatg ttggggataa atttggattc atgaaaacat
     3361 ctatcgacta tgccttagaa cacccacagg tcaaagagga cttgaaaaat tacattatca
     3421 aactaggaaa agctttggaa aaaagtaaag taccaacaca ttcaaagtaa tgtgttggta
     3481 ctttactttt ttccttgttt atagcaactt aagtttatat cttgaaaatt gtcaacgttc
     3541 caaaatataa aagctttgtg ttatacaact ttactagagg gacatattaa taataggatt
     3601 tatacgtaga aaaatgataa acataagtac agcttttgtt aaaactaatt aacaagaact
     3661 tcaaaactaa atagttat
//
LOCUS       DAUGSW010000070         3048 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUGSW010000070 DAUGSW010000000
VERSION     DAUGSW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.070"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            34..771
                     /locus_tag="VIB18_001582"
     CDS             34..771
                     /locus_tag="VIB18_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8766563.1"
                     /translation="MNQLLLKNVCKRYPNQPNYALDHINLTVRKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGNIYCADKEISTFSDKEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVILLKDGK
                     LHLEIDKKDCGESFYDVISQTLSDRGE"
     gene            952..2679
                     /locus_tag="VIB18_001583"
     CDS             952..2679
                     /locus_tag="VIB18_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8766564.1"
                     /translation="MIFLIIFLVVFLIYFNNFFVKKRSQELGVLAILGFSKKELTQLL
                     TLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITANEIIESLGILVV
                     VFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLATVF
                     SFTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKENKKRLYRPLSNIIY
                     PKFNYRIATKNKLLTVLGGLLTITVSVAGMMVMLYAYSLNGIERLTPSAIEYNVKSEN
                     GRVNVTTILENDQVSLVDVGLLRLNTIPEVTITDSGQTIPYFDIINYSDYKELMKAQG
                     RTNSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTLVV
                     SDKLYAKLSSCFPEKEMTIRTFNGTSIRSSEAFYNQFSMVPDVISSYSKEYTVKTANI
                     ATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYETG
                     ILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVLTL
                     RSVTSIIKN"
     gene            2719..>3048
                     /locus_tag="VIB18_001584"
     CDS             2719..>3048
                     /locus_tag="VIB18_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766565.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYT"
BASE COUNT         1020 a          419 c          529 g         1080 t
ORIGIN      
        1 gtacatgaac aactatcagg aggaagagat aaaatgaatc aattactatt gaaaaatgtt
       61 tgcaaaaggt atccaaacca accgaattat gctttagacc atatcaattt gactgttaga
      121 aaaggagaat ttgtagctgt catgggacgt agtggtagtg gaaaaacaac acttttaaat
      181 gttacttcaa ttattgataa aattgatagt gggaatattt attgtgcgga taaagagatt
      241 agcacatttt ctgataagga ggcaactagt tttagaaaaa atgatattgg ttttgttttt
      301 caagattata tgctgttaga tagtctaacc attagggaga atatttctgt tgctttgtct
      361 ctaaaaaata ttgattcttc aaagattgat gatttgataa atagctatgc aaaaagattt
      421 aatttatatg agcagttgaa aaaatatccg tatcaacttt ctggaggtca aagacagagg
      481 gtcagtatta tcagagcaat cattaaagaa ccagagatta tttttgctga cgaaccaact
      541 ggagcacttg acttgaaatc ttctgaggaa acaatgatga ttttgagtga aatcaataaa
      601 acagaaaagg taactatttt aatggttact catgacgttt tatcagcttc ttatgccgac
      661 agagttatac tcctcaaaga tggtaaactt cacctggaga ttgataaaaa agattgtgga
      721 gagtcgtttt acgatgtaat tagtcaaact ttatccgata gaggagagta atatgatttg
      781 gtccattaca aaatctaaca ttaaaaaaat ttttcgttat atcgtatcta ttttctagct
      841 acgattggtt tattaagtat ttttatagct tttctaaatt ttatctcaga taaaatcatt
      901 acagaaaaaa ttggggatag tggtcaagct ctagttatcg ctaatgggtc attgattttt
      961 ttgattatat ttttggtggt attcttaatt tacttcaata atttctttgt aaaaaaacgt
     1021 agtcaagagc ttggagtctt agcaatacta gggttttcaa aaaaagaatt aacacaatta
     1081 ctgactttag aaaatcttgt tattctagtt ttaagttact tggtaagttt actattggga
     1141 ccgaccttat attttttagc ggtactggta attactcatc tattggaatt aacattggaa
     1201 gttcagtggt ttattacagc taatgagatt atagagtctt taggaatatt agtcgtagtt
     1261 tttctgatta atgtcatcac aaatggactt atcattagta aacagtcttt gattgaattt
     1321 gttaatttct caagaaaggc tgagaaaaaa attaagataa gaaaagtcag agctattatt
     1381 gctatcactg cattgctatt gtcatatatt ttatgtttgg cgacagtatt ttcattcaca
     1441 cgaaatatgc tattaagcat agggatggta ccggtttctc tattgataat tgtcttagtt
     1501 gttttgggaa cagtgtttac catcagatat ggattggctt ttgtagtttc attgttaaaa
     1561 gaaaataaaa aaaggttata ccgtcctctc tctaatatca tctatcctaa atttaactat
     1621 cgtattgcaa caaaaaataa attattaaca gtcttgggag gtcttttaac aataactgtt
     1681 tcagttgccg gaatgatggt aatgctctat gcttattctc ttaatgggat agagaggttg
     1741 actccatctg ccatagaata taatgttaaa tcagaaaacg gtcgcgttaa tgttacaact
     1801 attttagaga acgaccaggt gagcttggtt gatgttggcc tgttgcgatt gaatactatc
     1861 ccagaagtaa ctatcacaga ctctgggcaa acaatacctt attttgatat aattaactac
     1921 agtgactaca aagagttaat gaaagctcaa ggcagaacaa attctattga aggtagtaag
     1981 tcactcccat tgttaataaa ttattatcca acagaaatta gtcttggaaa aacctttaac
     2041 ttaggaaatg catatgatgt tactgtaaaa caagtatcaa cgcataatgt ttttagtttt
     2101 tctacaagtg tcacgacctt ggttgtttct gataaattat atgctaaact tagttcttgt
     2161 tttccagaga aagaaatgac aattaggact tttaatggaa cttcgattag gtcaagtgaa
     2221 gcattttaca atcagtttag tatggttcct gatgttatca gtagttatag taaggaatac
     2281 acagtaaaga ctgctaatat tgcgacttat atctttataa ctttcctatc catactcttt
     2341 attatttgta caggtagtat tctgtacttt acaagcctca tcgaaatcat ggaaaataaa
     2401 gaagaatatg gctatctaag taagctaggt tatagtaaaa aaatgattca tcggattctt
     2461 cgatatgaaa caggtatact tttccttatt cctgtattca ttgggattgt aaatggtggt
     2521 atgttgctta tttactataa atatttattc atggatacat tggtagcagg caatatcata
     2581 atgttatctt tattgctttg tctgcttttc ttcttgataa tatatggcac attttatgta
     2641 ttgacattgc ggtcagtgac atccataatc aaaaattaat tttaaaaatc ttttaacttt
     2701 aacgattaag taaataatat gataagaata aaaaacataa caaagagtaa gttctttggg
     2761 actgcaataa tcttgttgca acaattaata gccttgttaa ttttggtcta taatcgagag
     2821 aacctgtctc ttcttttctc tgaaaaagta gctcttgtaa tgacccttat tgatacagct
     2881 tttatttggc tggcaacaat attacgccaa aaacaaggtg atatttttaa aagaattatt
     2941 tctatcatct ccttaacaat ttggcaatac ttagtatctg tgctgacaag aggaactcct
     3001 ctctttttaa gcagtggact acagattata ttgctctatt gttatacc
//
LOCUS       DAUGSW010000071         3025 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUGSW010000071 DAUGSW010000000
VERSION     DAUGSW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3025
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.071"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(270..1142)
                     /locus_tag="VIB18_001585"
     CDS             complement(270..1142)
                     /locus_tag="VIB18_001585"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEQ8766566.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1366..2676
                     /locus_tag="VIB18_001586"
     CDS             1366..2676
                     /locus_tag="VIB18_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEQ8766567.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            2754..>3025
                     /locus_tag="VIB18_001587"
     CDS             2754..>3025
                     /locus_tag="VIB18_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8766568.1"
                     /translation="MPRKTFDKAFKLSAVKLILEEEQSVKMVSSTLEIHPNSLYRWIQ
                     EYEKYGESAFPGHGSALRHAQFEIKKLEKEHKLLQEELALLKKFQV"
BASE COUNT          886 a          694 c          536 g          909 t
ORIGIN      
        1 ctcctagtta acgactttga ttgattttat tatgatgaat cgtgatttct gaaaacaaaa
       61 ttttcttcat ggatttggcg tggaactttt acaataaaaa cactaacctc tccctatcgt
      121 tttttcaggt gaatgcttgg aattggtata ataagcggac acgaatcagg tgaaaacagg
      181 gaaagtattt gaagagacgt ttaaactatc tgacataaaa ctcgttctag aggaaagaca
      241 tcctttaaaa agttagttta ttttgcaact tagacatcaa ggtaggttaa acccttcatg
      301 gaaaaatcga gactcttagc actatgggtt aaactaccac tggagacgta atcaatcgct
      361 aaaccacgaa aacggctaat agtggtcata tcaatatttc cagaacattc aatccgagaa
      421 cgtcctgcaa ttagagtaat ggcctgttca atctgttcca atgacatatt atccaacatg
      481 ataatatcaa cacccgccgc cgcagcttct tcggcagcag caaggctttc cacttccacc
      541 tcgaccattt tcacaaaagg ggcataggca cgcgcttgag caatcgcctt ttgaacacta
      601 cctactgccg caatgtgatt gtcttttagc atgatagcat ctgataaatt aaagcgatga
      661 ttatagccac cgccaactct cacggcatat ttctcaaaaa gacgtaaatt aggagtggtt
      721 tttcgagtat caaatacctt aatgcgatca tcgcctaagg cttctacata agcagctgtc
      781 atcgaagcaa tccctgataa atgttgtaaa aaattcaagg caacgcgttc acatgttaag
      841 aggcttctca ccgagcctat gatttctaaa accaaatcgc cactagtcaa acgatcccca
      901 tccttaaatt gatgaggatt ctggaaggtc acctcggcat caaatagggt aaaaaccctt
      961 tgaaaaacgg ttagccccgc taaaacacca gcttccttgg caaaaagcga caccttggct
     1021 tggccatgat gatcaaaaat ggcattggta ctgtaatctt cggaatgaac atcttctcgc
     1081 aaggctgctt tcaatgtatc atctatttga aaaggggtta aatcagttga aatgattgac
     1141 atcactaagt cctctatttt taatatcact tgtaagcact agaggcaatt gctattaact
     1201 tccgtaggaa atcacaaacc tgaatacctc gttttaaatt ccaacaagtg tcaagacaat
     1261 tgtaattttt ttgtgtataa tagtcaagta ccaataggaa acaggtggtc ttttgagcgc
     1321 caaaattgcc aacctatttt catattctaa ctaaaggaca attcaatgat tcatttaata
     1381 ataattagcg ccattgctct agccattgga attggttacc gcaccaaaat caatattggc
     1441 ctactggcta ttgctttttc ttacctcatc gcaaccactc tcatgggatt aagccccaaa
     1501 gaacttcttc atttttggcc aacctcactc ttttttacca tttttagcgt ctctctcttt
     1561 tataacgttg caacaactaa cggcactctt gatgttttgg ctcaacacat tctctaccgc
     1621 acacgcaccc accctaacgc cctctacatg attttatacc tgatagcaac ccttttgtct
     1681 gctttaggtg ctggattttt cactactatg gccgtttgct gtcctctagc gattaccctc
     1741 tgtcaaaaag cggacaaaca ccctttgatt ggagctcaag ccgtcaattg gggagcttca
     1801 ggaggggcta atttgataac cagtggctca ggcattgtct ttcaaggcct gtttaagcaa
     1861 atgggatggg aagagcaagc tttttcactt ggcaatcata tctttatcgt cagcattatc
     1921 tacccactca tcgtcttgct tttattatct tgttacatcc gctacagtaa gggaagaaca
     1981 aactcatcct tgactattga ccaaccacca gtcctcagca aggtccaaag acaaaccacc
     2041 ttgctcatga tcagcagcat ggttttggtt tggctttttc ccttgttgca tctcattttc
     2101 ccaaacatcg catggatagc tacttatcga caaacatttg atattggctt tgtctcaata
     2161 ctcatggtct gcctcgcctt aaggctcaaa ttagggaagc aagaagccat tttggctaag
     2221 gttccctggg ctataattat catgctctgc ggcatgagct tactaatgtc tctagcggtc
     2281 aagtcaggtt tagttacact gatagggcac ctcataacaa caaccattcc tcatttctgg
     2341 ttacctctgt tcttttgtgt gatagccgga gtgatgtcac tctttagttc caccctatcc
     2401 gttgtagccc caactctctt tcccatcatt gctaccatca gtgctcaaag tcctcacatt
     2461 gatattcgct tactcacaac agccactatt attggcgctc tatctactaa tatctctcct
     2521 ttttcatcag ctggttccct cattcaactc tcccttcccc atatagagga acgcagtctt
     2581 gctttcaaaa aacaaattct tctgggtgtg cccatcagct taagtttggc actcttgacc
     2641 atctggattc tcatgctgct agcttcctta agttagattt attgtctaac ttaaggttgg
     2701 acttggtata ataaagtaga cacaaaatta agtggaaacg aggaaaagtc attatgccaa
     2761 gaaaaacctt tgataaagcc ttcaaactct ctgctgtaaa actcatcctt gaggaagagc
     2821 agtctgtaaa aatggttagt tcaactttag aaattcatcc caatagtctt tatcgatgga
     2881 ttcaagaata tgaaaaatat ggagaaagtg cgttcccagg acatgggagc gcacttcgtc
     2941 atgctcaatt tgagataaaa aaacttgaaa aagagcacaa actgctacag gaggaattag
     3001 ctcttctaaa aaagttccag gtctt
//
LOCUS       DAUGSW010000072         2999 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUGSW010000072 DAUGSW010000000
VERSION     DAUGSW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2999
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.072"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..182
                     /locus_tag="VIB18_001588"
     CDS             <1..182
                     /locus_tag="VIB18_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tRNA(Ile)-lysidine synthetase"
                     /protein_id="HEQ8766569.1"
                     /translation="IRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKH
                     DIMLAKLYIDKLEKG"
     gene            187..729
                     /gene="hpt"
                     /locus_tag="VIB18_001589"
     CDS             187..729
                     /gene="hpt"
                     /locus_tag="VIB18_001589"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEQ8766570.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            751..2730
                     /gene="ftsH"
                     /locus_tag="VIB18_001590"
     CDS             751..2730
                     /gene="ftsH"
                     /locus_tag="VIB18_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEQ8766571.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
BASE COUNT         1042 a          420 c          622 g          915 t
ORIGIN      
        1 aaataagacg tttatttata gatgaaaaat tcacaatagc tgaacgtcaa aatgctatta
       61 ttggagagca agatgagcag attatatttg tattgatagg taataaaact tatttgagaa
      121 aagcttgtaa acatgatata atgttggcta aactgtatat tgataaatta gaaaaagggt
      181 gacagcatgc tcgagcaaga tattcaaaaa attctttact ctgaaaatga tattattcgg
      241 aaaactaaaa aattaggaga acaattaaca aaagattatc aagaaaaaaa tccgcttatg
      301 attggtgtat taaaaggatc agttcctttt atggcagaac taatgaaaca catcgatact
      361 catgttgaaa ttgattttat ggtagtatca agttatcatg gcggtacatc tagcagtggt
      421 gaagttaaaa ttttaaaaga tgtagatacc aatattgaag gaagagatat cataattgtt
      481 gaagatatta ttgacaccgg tcgcacctta aaatatttac gagatatgtt taagtaccgt
      541 aaagctaata ctatcaaaat tgcaacactg tttgataaac ctgaaggtcg tgttgttaaa
      601 attgaagcag attatgtttg ttacaatatt ccaaatgaat ttatcgtagg ctttggttta
      661 gattacgcag aaaattatcg caatcttcct tacgtaggtg tattaaaaga agaagtctat
      721 tcaaaataga aaaaggtcaa tgtttactgt atgaaaaata ataaaaataa tggttttgtt
      781 aaaaattctt ttatatatat attgatgatt attgttgtca tcacaggatt tcaattttat
      841 cttaagggaa ccagcacaca aagccaacag attagttatt ccaaattaat taaacatctt
      901 aaggctggag atataaaatc tttaagttat cagcctagcg gtagtattat tgaagttaaa
      961 gggaaatatg agaaacctca aaaagtgaca gttaattcag gactatcatt tttaggtgga
     1021 agagcttcaa cacaggtaac agagttctca tctttagtat tacctagtga taccatcttg
     1081 aaagaaatga cagcagcagc tgataaaaat ggaacagagc ttacagttaa gcaggaaagt
     1141 tcaagtggta cttggattac cttcttaatg agctttttac ctattgttat ttttgctgct
     1201 ttcatgatga tgatgatgaa tcaaggtggt ggaggagctc gtggtgctat gagtttcggc
     1261 aaaaataagg caaaatctca atcaaaaggt gatgttaaag tgagatttac agacgttgct
     1321 ggtgccgaag aagaaaaaca agaattagta gaagttgttg attttttgaa aaatcctaaa
     1381 aaatataaat cactaggagc acggattcca gcgggagttc ttctagaggg gcctccaggt
     1441 actggtaaaa cattactagc taaagctgta gcaggtgaag ctggagtgcc atttttcagt
     1501 atttcaggtt cagattttgt cgaaatgttt gtcggtgtag gtgctagtcg tgttcgttct
     1561 ttatttgagg atgctaaaaa agctgagcgt gcgatcatct ttatcgatga aattgacgct
     1621 gtaggtcgtc gtcgtggtgc tggcatggga ggcggtaacg atgaacgaga acagaccctt
     1681 aaccaattac tcattgaaat ggatggtttt gagggtaatg agaacattat cgttattgct
     1741 gcaactaacc gtagtgatgt tttagatcca gcgttactaa gaccgggtcg ttttgatcgt
     1801 aaggttttag ttggtcgccc tgatgttaaa ggacgtgaag ccattttacg tgttcatgct
     1861 aaaaataaac cacttgcaaa tgacgttaat ttgaaagtag tagcccaaca gactccaggt
     1921 tttgtaggtg ctgatcttga aaatgtttta aatgaagctg cgttggttgc tgctcgcaga
     1981 aataaaatta aaattgatgc tagtgatatt gatgaagctg aagatcgtgt tattgctgga
     2041 ccatcaaaga aagatcgcac tatttcgcaa aaagagcgag aaatggttgc ttatcacgaa
     2101 gctggtcata ctattgttgg tttagtttta tctaatgcgc gtgtagttca caaggtaact
     2161 attgtacctc gtggacgagc aggtggttat atgatcgctc ttccaaaaga agatcaaatg
     2221 cttctttcta aagaagatct gaaagagcaa ttagcaggat tgatgggtgg tcgtgttgct
     2281 gaagaaattg tttttaatgc tcaaacatca ggtgcgtcaa atgactttga gcaagctact
     2341 cagatagcaa gggccatggt tacggaatat ggtatgagtg aaaagcttgg accagttcaa
     2401 tatgaaggta accatgcgat gatgccagga cagatctctc ctgaaaaagc ttactctgcc
     2461 caaacagctc aaatgattga tgatgaggtt cgtgaactct taaatcaagc tcgtaatcaa
     2521 gcagctgata tcatcaatga gaatcgagat actcataaat tgattgctga agctcttctc
     2581 aaatatgaaa ctctagacgc tgcacaaatt aaatcaattt atgaaactgg taaaatgcca
     2641 gttgatttag aaactgatga taatgaagct catgcgttat cttatgacga aattaaaaat
     2701 aaaatgacag aatctgaatc tgcagaatga gataaaaaag ctgaacttat agattaagtt
     2761 cagctttttt atcaacacaa tatccttgta aacgttatga attgtaatag gtgcctaatt
     2821 gctagaaatg agaagatgac atactttttt tctttattac ttaaagtgag aaagactttg
     2881 gtatttaaaa ctagaaaatt gttaaagcca tttgaaaaaa tctattagtg ttttcttaga
     2941 ataatagaag aacagaagat agcaaaagtt tcagtcaacc aataagatga aatttacaa
//
LOCUS       DAUGSW010000073         2771 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUGSW010000073 DAUGSW010000000
VERSION     DAUGSW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.073"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            67..717
                     /locus_tag="VIB18_001591"
     CDS             67..717
                     /locus_tag="VIB18_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8766572.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            720..1388
                     /locus_tag="VIB18_001592"
     CDS             720..1388
                     /locus_tag="VIB18_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8766573.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKENA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            1397..2629
                     /locus_tag="VIB18_001593"
     CDS             1397..2629
                     /locus_tag="VIB18_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8766574.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSVMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
BASE COUNT          921 a          400 c          556 g          894 t
ORIGIN      
        1 aaataaagat aaccgatcat tgtagagatt taagcatttg ttgagaaaat ttgttataat
       61 aagcgtatga aagaaagact agaacattat tctaccagct ctatatatag cggatttgaa
      121 gtgtacttgc cgttggtact acagacaata acagatgtga ttattgctga gaatatcaaa
      181 agcaaaaaag aaacagggtt taaactatat gaacacttta catcccgtat taaatcggaa
      241 gcttcgatga ttgaaaaatg tcaacgcaaa caacttcctc taacaagcaa atctgcgtta
      301 aaaatcatta aagatagtat cggtattcgc attatttgtg gttttattga tgatatttat
      361 cggatggtag acttgctcaa aagcattcct ggtatgtcag ttaacactga aaaagattat
      421 attttaaatg ccaagcctaa tggctataga tcatatcatc tcattttgga attagaaaca
      481 cattttccag atattttagg ggaaaaaaaa ggatgttatt ttatagaagt gcagttgcga
      541 accattgctc aagactcttg ggctagcttg gaacatcaaa tgaagtacaa acatcaagtt
      601 gctaatgcag aaatgattac aagagagtta aagcgttgtg cagacgagtt ggcatcttgt
      661 gatgttacca tgcaaaccat tcgtcaattg attcaagaaa cgacggagga agagtaacca
      721 tgaaaatttt gttagctgaa gacgaatggc agatgtctaa tgttttgaca actgccatga
      781 ctcatcaagg ttatgacgtt gatgtggttt ttaacggtca agaggcaatt gataaagcca
      841 aagaaaatgc atatgatatt atgattttag atatcatgat gccgattaag tctggcattg
      901 aggctttaaa ggagattcgc gcttcaggaa attgctcaca tattattatg ctgacggcta
      961 tggcagaaat taatgaccgt gttaccggac tagatgcggg agctgatgat tatctgacta
     1021 aacctttctc attaaaagaa cttttagcta gattaaggtc gatggaaaga cgagtagaaa
     1081 gttttactcc tcaggtatta caatttgctg gtgtcacatt aaatattaat gagcaagaat
     1141 tgagtgccgg taatgctata cgattagctt ctaaagaagg taaattaatg gcctttttaa
     1201 tgttaaatca aggaaagtac ttggatacta aaacgcttta ccaacatgtt tggtcagacc
     1261 aagaagatta tgatacttct attgtttggg tttatatttc ttatcttcgt caaaaattat
     1321 tagctattca agcaaatgtc attattgcag gtgataaaga tactagctat tgtttattag
     1381 aaaaatagga ggtgacatgt ttaatcgtat ccgtattcgt tttatcatga ttgcttctat
     1441 tgccattttt attattttaa gttcaattgt tggtattatt aacacggcac gctgttacca
     1501 aagtcaacaa gaaattaacc gtattttaca tttaatttcc tcaaataaag gtaaattacc
     1561 tggcactacg gaaagctcta aacgacttgg aacgaaactg tctgaagata gcctaagcca
     1621 gtttcggtat tatagtgtca tttttaatgc taatggacat ctactttctt ctaatactgc
     1681 taatatttca gctttagata gagaagaagc ccaatatttt gctagacttt ttgctaagtc
     1741 tggggaagaa aaaggcagtt accgtcacca agatagtgtt tattcgtact tgattactca
     1801 gctgccaaat gaagaaaaac tggttgtaat tttagatact accttttatt ttcgtagtgt
     1861 aggagattta ttagctgttt cagtgatgtt ggcttttgga ggatttatct tttttgttgt
     1921 tttagtgagt cttttttccg gtatggtcat caaacctttt gtccaaaatt atgagaagca
     1981 gcgtcgcttt attactaatg caggccacga gttaaaaaca ccactagcca ttatctcagc
     2041 caataatgaa ttggtcgaat taatgactgg agaatcagaa tggaccaaga gtacaagtga
     2101 tcaggtgaag cgattgacag gcttgattaa tcaaatgatt actttggctc gtttggagga
     2161 acagccagat gtggtattac atatggtaga cttttcagct attgctcaag atgcagctga
     2221 agattttaag agtctggttt tgaaagatgg taaacgtttt gatttgacga ttcagccgaa
     2281 tattatgatt aaagcggagg aaaagtcatt gtttgaactt gtgacaattt tagttgataa
     2341 tgccaataaa tattgtgatc ctaaaggctt ggtcaaggta tctttaacca ctattggaag
     2401 aagacgaaaa cgagcgaaat tagaagtttc taatacctat ttggaaggaa aatccattga
     2461 ttacagccgc ttttttgaac gcttttatcg cgaagacgaa tcccataata gcaaagaaaa
     2521 aggttatgga attggtttat ctatggcaga aagtatggtt aagttattta aaggaacgat
     2581 aactgtaaat tataaaaacg atgctattgt ttttacagtg gtgatttgac ttaaacattt
     2641 ttcagtatct ttagctagta ataatgtcta ggtaaaggta ataaacgatg cttaaccagc
     2701 ccatgaggct ggtttttaac gtttaattta gtagaagagt gattaaagaa ggtagtttga
     2761 aataagaaaa t
//
LOCUS       DAUGSW010000074         2613 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUGSW010000074 DAUGSW010000000
VERSION     DAUGSW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.074"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            14..685
                     /gene="sdaAB"
                     /locus_tag="VIB18_001594"
     CDS             14..685
                     /gene="sdaAB"
                     /locus_tag="VIB18_001594"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEQ8766575.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVYSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            697..1569
                     /gene="sdaAA"
                     /locus_tag="VIB18_001595"
     CDS             697..1569
                     /gene="sdaAA"
                     /locus_tag="VIB18_001595"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEQ8766576.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKKQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIESQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(1983..2597)
                     /locus_tag="VIB18_001596"
     CDS             complement(1983..2597)
                     /locus_tag="VIB18_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEQ8766577.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
BASE COUNT          812 a          487 c          494 g          820 t
ORIGIN      
        1 aacggagttg cctatgaata cacaaaaatt tcaatcagtt tttgacatca ttgggccagt
       61 aatgattggt ccatcaagta gtcacacagc tggtgccgtc agaattggta aggtagtcta
      121 ttccatcttt ggagatattc ctgatgaagt gacgtttcac ctttataatt catttgctaa
      181 aacctacaga ggacatggta ctgataaggc tcttgttgca ggaattatgg gtatggatac
      241 tgataatcct gatattaaaa attctctaga aattgctcat caaaaaggga taaaaatcta
      301 ttgggatatc ttaaaagata gtaatgctcc ccatcccaat actgttaaaa tcagtgtcaa
      361 aaaagctgac aaaacactta gtgttactgg tgtttcaatt ggaggaggaa acattcaagt
      421 aacagaacta aatggttttt ctgtctcgtt atccatgaat actcctacta tagttactgt
      481 acacaaagat attcccggaa tgatcgcaaa ggtaactgat atcctatctt ccaataatat
      541 taatatcgcc acaatgaatg ttacacgtga atctgctggt gaaaaagcta ctatgattat
      601 agaagtcgat tctagagagt gccaagaagc agccaaccaa attgcaaaaa ttcctcatat
      661 ttataatgtc aacttctttg actagaaagg aaagctatgt tttatactat tgaagaactt
      721 gtcaaacaag ctgaccaaca atttaatgga aatattgctg aactcatgat tgccacggaa
      781 gtggagatgt ctggaagaaa tcgagaagat attatcaaaa tcatgtcacg caatttacaa
      841 gttatgaaag cagctgtaac agaagggcta acctcaacca aatctatcag tggtttgaca
      901 gggggcgatg cggtcaaaat ggataactac attaaaaaag ggaacagcct ttctgatact
      961 actattctta atgctgttag aaatgctata gctgtaaacg aattaaatgc taaaatggga
     1021 cttgtctgtg caacacccac tgcaggaagt gcaggatgct taccagcagt gctcgcaaca
     1081 gctattgaaa aacttgactt atcagaaaaa aaacaattag agtttttatt tactgcagga
     1141 gcttttggtc ttgttattgg aaataacgcc tctatttctg gtgcagaagg tggatgccaa
     1201 gcagaagttg gttctgcagc tgctatgagt gcagctgctc ttgttaaagc agctggtgga
     1261 acatctcatc aagctagtca agctattgcg tttgttatca aaaatttatt aggacttgtc
     1321 tgtgatcctg ttgccggcct agtagaagtg ccttgtgtca aacgcaatgc cctaggagca
     1381 agtttcgccc ttgtcgcagc tgatatggct ttagctgata ttgaatctca aattcctgtt
     1441 gacgaagtta ttgatgctat gtatcaagtc ggctctgcca tgccaactgc tttccgtgaa
     1501 acagcagaag gtggtctagc cgctactcca actggacgac gttacagcgt agaaatattt
     1561 ggcgaataaa tagatagtta gaaaaattct tagaaatatt tgaaagcgtt ttatttttat
     1621 gctatatatt cactaaaatg actaatagat agctatcaag ctatgttgtt tccccttaga
     1681 aacaacttct agtaaattgt taaaactcaa aagtgtagta gtgtaaaata ctgaaaattg
     1741 ctaatgacct tataaacatt taagagtttt tttcctgctt gttatcagta taactgcctt
     1801 aaatatcaga ggcacttaag tgctggtcag ttttcctaaa taatacgagc tatattccct
     1861 gataaggcaa tgttttgttt tgagactaat tcatcactac aaatcataaa gacaattaaa
     1921 taccaaaaac ctattgttag taaatactaa caataggttt tatttcttcc agccatgttt
     1981 atttagtaac cccaagctga taaaccttgt gcactatagg ctttcaaggc tgcattgact
     2041 tgatcttcaa ccgttgctgt agaaccccaa cctggcattg tctggaacaa ccctgatgcc
     2101 ccagaagcat tagctgcgtt aggatttcca ttagattcac gcgcaattat atgttcccaa
     2161 gttgattgtg gaacacctgt tgctgctgcc atctgtgccg ccgcttgact tcctacaata
     2221 ccagcagtat ttccattgga aagtaccaca ttgtttggat tataggctac tgaagatacc
     2281 tgctgaacag tttgagtcac ttcttgctga acaaccggtg cttcctctgt tactgtcgga
     2341 gctacagagt tttctactgt gggaataggc tccgaagcaa tgctctttgc tttttctttg
     2401 ctttcttctt tagtaatagc atgattattt tttggagcct tgtcgattgt taccatttta
     2461 ctttctgact tcttagcata agacttagta tcagcatttt tacttgagaa ggcaaaaatg
     2521 atggctaata ttgttagagc taacgctact aatccaaaat taaaataacg ttgttttaaa
     2581 ttttctttct taaacattca ataatacctc act
//
LOCUS       DAUGSW010000075         2600 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUGSW010000075 DAUGSW010000000
VERSION     DAUGSW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.075"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..694
                     /locus_tag="VIB18_001597"
     CDS             <1..694
                     /locus_tag="VIB18_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8766578.1"
                     /translation="QVKKLKQALDKIIASIESTDISKMSREVSRINNSLQADNDYIKQ
                     KYFIEYDIFEKDILARTGLLEIDWENVSDDIEPLKIHRNFYESISEKTDSEVIEEIKN
                     LEDINFTDEKGNDLDDLTIIVPAQDEGFKRVFLGQREWYDIRIGKSKRNRIKYIAGYE
                     VAPESGVKYWAEVDKIVPSDNYVGYWKVIFKGEVKEYSEYKRLGNTWPPQNSRYVSKK
                     ALDEAKYLSDVF"
     gene            714..2006
                     /gene="purB"
                     /locus_tag="VIB18_001598"
     CDS             714..2006
                     /gene="purB"
                     /locus_tag="VIB18_001598"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEQ8766579.1"
                     /translation="MIERYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEQYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDIKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
     gene            2139..>2600
                     /locus_tag="VIB18_001599"
     CDS             2139..>2600
                     /locus_tag="VIB18_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8766580.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKVAVDIIQAKFEVYQTGDINFGYSILKEFLPQLKRKS"
BASE COUNT          879 a          414 c          575 g          732 t
ORIGIN      
        1 acaagttaaa aaattaaagc aagcattgga taaaataata gcctctatag agtctacaga
       61 tatttctaaa atgtcacgag aagtgtcacg cataaataac tccttacaag ccgataatga
      121 ctacatcaaa caaaaatatt ttatagaata tgatattttt gaaaaggata tattagctag
      181 gacagggtta ttagaaattg attgggaaaa cgtttctgat gacatagagc ccttaaagat
      241 acatcgtaac ttttatgaat caattagtga aaaaacagat tctgaagtta tagaagaaat
      301 caaaaattta gaagatataa atttcactga tgaaaagggt aatgatttgg atgacttaac
      361 cattattgtt cctgcgcaag acgaaggatt taaaagagtc tttctaggtc aacgagaatg
      421 gtatgatata cggataggaa aatcgaaaag gaataggatt aaatatatcg caggatatga
      481 agttgcacca gagagtggtg taaagtactg ggctgaagtg gataaaatag ttccttcaga
      541 taactatgtt ggttactgga aagtaatttt taaaggagag gtgaaggaat attcagaata
      601 taaaagatta ggaaatactt ggccccctca aaacagtaga tacgtatcta aaaaggcttt
      661 agatgaagct aaatatttat cggatgtttt ttaattaaag gagaaaaaac aaaatgatcg
      721 aacgttattc acgccctgag atggcggcaa tttggacaga ggaaaataaa taccgtgctt
      781 ggttggaggt tgagattctg gctgacgagg catgggcaga gttgggtgag attcctaagg
      841 aggatgtggc taagattcgt gagaaggcgg attttgacat tgaccgcatt cttgagattg
      901 agcaggacac acgtcacgat gtggtggctt tcacgcgtgc ggtttctgaa acgcttggtg
      961 aggagcgcaa gtgggtgcac tacggtttga cgtcaactga cgtggtggac actgcctacg
     1021 gttacctcta caagcaagct aacgacatta tccgtcgcga tcttgagaat ttcaccaata
     1081 tcgtggcaga caaggcgcgt gagcacaaaa tgaccatcat gatgggtcgt acccacggtg
     1141 ttcacgccga gccaacgact ttcggtctta agttggcgac ttggtacagc gagatgaaac
     1201 gtaatattga gcgttttgaa catgctgccg caggtgtgga agctggtaag atttcaggtg
     1261 ccgttggtaa ctttgccaac atcccacctt ttgtggaaca atatgtctgt gacaaattag
     1321 gcattcgtcc gcaagaaatt tcaacacaag ttcttccacg tgaccttcac gcagaatatt
     1381 ttgcagtgct tgcaagtatt gcaacatcta tcgaacgtat ggcaacagag attcgaggtc
     1441 tgcaaaagtc agaacaacgt gaagttgaag aattctttgc caaaggtcag aaaggtagct
     1501 ctgctatgcc tcacaaacgc aacccaatcg gttcagagaa catgacaggg ctagcgcgcg
     1561 tgattcgtgg tcacatggtg acagcttatg agaacgtgtc actttggcat gagcgtgata
     1621 tttcacactc atcagctgag cgtatcatca cacctgacac aactatcttg attgactaca
     1681 tgctcaaccg ctttggcaat atcgttaaga acttgactgt cttcccggaa aatatgatgc
     1741 gcaatatgga atcaactttt ggtttgattt atagtcaacg tgttatgctc aaattgattg
     1801 aaaaaggaat gacacgagaa gaagcttatg acttagttca acctaagaca gcttattcct
     1861 gggacaatca agtggatttc aaaccacttt tagaagaaga catcaaagtt acctcttgtc
     1921 ttacacaaga agaaattgat gaactattta atccgattta ttacacaaaa cgtgttgatg
     1981 atatttttaa gcgtttaggg atttaatata aaaaaagaag gtgattccct tctttttttg
     2041 tttaaaaaaa cgaatatttt ctttaaaaat atcaaaaagg ttagtttttt gattagacgc
     2101 tgtgatataa taaagaaaac agttgttgga gagaaaccat gttagaacat tttggtggaa
     2161 aagtaaaagt gttaagactt gaaaagagga ttagtcgcga ggacttgtgt ggggatgagt
     2221 ctgaactttc tgttcgtcaa ttagcacgga tagaactagg tcaatccata ccaagtttaa
     2281 gtaaggttat ttttattgca aaagccttaa acgttagtgt cggttactta actgatggtg
     2341 ctgatttaga actacctaag cgttacaaag aattaaaata ccttatctta aggacaccaa
     2401 cttacatgga tgatggaaaa ttacaagtac gagaagagca gtttgatgaa atttttgagg
     2461 attattatga taaattacca gaggaagaga aagttgctgt tgatattatc caagcaaaat
     2521 ttgaagttta tcaaaccgga gatattaatt tcggatatag tattttaaaa gaatttctac
     2581 cacagctaaa aagaaaatct
//
LOCUS       DAUGSW010000076         2533 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUGSW010000076 DAUGSW010000000
VERSION     DAUGSW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2533
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.076"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            32..445
                     /gene="yaaA"
                     /locus_tag="VIB18_001600"
     CDS             32..445
                     /gene="yaaA"
                     /locus_tag="VIB18_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEQ8766581.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRIGDKISLPDQDLIITIVEPSQEEREQFAEEIAEKTRVAALVKQMNQANKK
                     TSSKHKNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            447..1553
                     /gene="recF"
                     /locus_tag="VIB18_001601"
     CDS             447..1553
                     /gene="recF"
                     /locus_tag="VIB18_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEQ8766582.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(1609..2472)
                     /locus_tag="VIB18_001602"
     CDS             complement(1609..2472)
                     /locus_tag="VIB18_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEQ8766583.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
BASE COUNT          896 a          494 c          423 g          720 t
ORIGIN      
        1 taatgacttg aatgacaaaa tggagatgac aatgatatac aaattattta cagaatttat
       61 caccctacaa gcccttctta aagaattagg aattatccaa agtggtggcg ctatcaaggg
      121 atttctcgct gaaacaaccg ttctatttaa tggtgaagat gagaaacgtc gaggcaaaaa
      181 aatcagaata ggggataaga tttctctacc tgaccaagac ttaattatca ctattgttga
      241 gcctagtcaa gaagaaagag aacaatttgc cgaagaaata gctgaaaaga cacgtgtagc
      301 ggctctagtg aaacaaatga accaagctaa caaaaagact tcttctaaac ataaaaatcg
      361 tcaatctact accaaaaaat cactaagagc aactaagaaa actaaaggta aaccaactgc
      421 acctgtccgc ttcccaggta tctagtatgt ggattaaaga gttagagtta aaacattatc
      481 gcaattatga ccacctgctt gcctcatttt cgtcgggttt aaatgtcttt atcggtaata
      541 atgctcaagg aaaaaccaat tttctcgagg caatctattt tctatcactt actagaagtc
      601 atcgcacgag ggctgataaa gaattgattc attttgatca ctcaactgtt tctcttactg
      661 gtaagattca gcgtattagt ggtactgttg atttagaaat caatctatca gataaaggac
      721 gtgtgacaaa gattaatgcg ctaaagcaag caaaattatc tgattatatt ggaacgatga
      781 tggttgtgct ttttgcacca gaagatttgc aactagttaa gggagcacct agccttcgtc
      841 gcaaatttat cgacattgac cttggtcaaa ttaagcctgt ttacttatct gagttatccc
      901 attataacca cgtgcttaaa cagcgtaata gctatttaaa aagtgcccaa caaattgatg
      961 ccgcttttct agctgttcta gatgagcaat tagctggcta tggagcccgt gtcatggaac
     1021 atcgtattga ttttatcaat gcgttagaga aagaagcaaa tactcatcac caagccatct
     1081 caaatggttt agaaagtctc tctctctcct atcagtcgtc agttgtcttt gacaaaaaaa
     1141 ctaatattta ccaacaattt ttacaccaac ttgaaaaaaa tcatcagaaa gatttcttcc
     1201 gtaaaaacac tagcgttggt ccacatcgcg atgacttagc cttttacatt aacgggatga
     1261 atgctaactt tgctagtcaa ggtcagcacc gcagccttat tctttcctta aaaatggctg
     1321 aagttagttt aatgaaggcc ttgactggag ataatcccat tcttttacta gacgatgtca
     1381 tgagcgagct agacaataca cgacaaacaa agttacttga aacagtaatt aaagaaaatg
     1441 tccaaacctt tatcacaaca acaagtttgg atcacctgtc acagttgcca gaaggtatcc
     1501 gtatttttca cgtgacaaaa ggaaccgttc aaattgattc tgatattcac taataacatc
     1561 aaaaaagggt tcagttaaac tgagcctttt tttgatatta tgtggcgatt aagatttgac
     1621 cacacctaat aaaatagcac ctacgataaa acaaataatt cctgtgacaa cccaacgcat
     1681 ttcttttttg gttttggttt cgcctaggaa taaaatgcct ccgacaatcg aaatgatagc
     1741 acctaattgt gagaaactaa aggcaatagc aagtcctgct tttgatgcag ctaaaagcat
     1801 aaaaatattc ccaatgcccc aaagtaatcc aacaacacta tttttaatca catactggtc
     1861 aatggaaatt ttaaatgaca tgaaagttat agctcctaaa accataccta ctgccatggg
     1921 taaaatgact gacaaaactt caaatttcat gatgttatta aataatacag catacatcac
     1981 gtaaccaatt gttgaataag tgagcgccct aaatcctttt gaaaaattat gaaggtgatt
     2041 gacttgtgca ttagcatcat cttgtttact agaaaagtaa aaaccaacaa tcagaagtaa
     2101 tagtgctaga cttcctacta caaattgcat aggtcttgtc cattcatgaa aaacgaggac
     2161 accaatcaaa cttcccagaa caagttgaga gccacttgac aaaggattgg caacggagac
     2221 tcccatgtat tgcatggcat gaaattgacc agtttgacca attgaccaga taaaaccacc
     2281 caatattcca aaaagccaaa gttgcagtgt catctcaggt ctaacaatta accaaacagc
     2341 taatgaaaat aataaagccc caaaagtcat tcctagagtt tgttgcgaag gttttcctcc
     2401 aattttgtta ctaacaaatc caatgcttcc ccatgtaaac atgggaataa gtgcataaaa
     2461 aataccttcc aaaatgttat ctcctttata gtaaatcttt aaagattata ataattccat
     2521 cataaaatgg ttt
//
LOCUS       DAUGSW010000077         2462 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUGSW010000077 DAUGSW010000000
VERSION     DAUGSW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2462
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.077"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            199..933
                     /locus_tag="VIB18_001603"
     CDS             199..933
                     /locus_tag="VIB18_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ8766584.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIKGLDYKWSENTSIKEALNE"
     gene            926..1912
                     /locus_tag="VIB18_001604"
     CDS             926..1912
                     /locus_tag="VIB18_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ8766585.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKMFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1922..>2462
                     /locus_tag="VIB18_001605"
     CDS             1922..>2462
                     /locus_tag="VIB18_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8766586.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALM"
BASE COUNT          921 a          302 c          476 g          763 t
ORIGIN      
        1 ttaacaatga tttaggaata cattatgtag aactaggtaa aggaattatc gattataaaa
       61 caatcattca tgaaatccat gaacatttta tagacttaat ttttagttta gaagtacatg
      121 aaaaagaaat agacaaaaag gcagaagtag tgaggaagtc ttatctgaca ctaaatgagt
      181 atattaatgg aggctaaaat gaatttgagt atatttggtt taaagaatat tccttatttg
      241 aaagaagggg atagtataga aaagcttatt gaagaaagca ttaaaacttc aggatttttt
      301 atcgaagaca atgatgtgct ttgcatagct tctaaagttg tatctatcgc agaaggccag
      361 gtgatgtctt taaacgagat acaagtgagt gatgtagcaa aagaaatcca caggaatatt
      421 cctcgtaaag atcctagaat aattgaaatt atgctaaatt tagtcaatag agatctgtca
      481 cgtttagata tcaaaaaaaa ttacattggt tgtcgcttgg aaaatggttt aaagttgaca
      541 agtggtggaa tcgatagaaa atcagtagat gaagtattcc ttttacctaa taatccggat
      601 gcttctgcaa aaagaatttc ggaatatctt aaaaaatcac ttggaaaaaa tgttgcagtt
      661 gttataacag atagtgatgg tagagaggat aaaagaggtg ctactcaagt agcaattggt
      721 atttatggta ttcatccttt gagaaaaaca gaagtaatag attcacaagg agagacaata
      781 aaattccaag aagagacttt gtgtgatatg attgcagctt gtgctggctt agtaatgggg
      841 caacgtggaa ctggaattcc agctgtcctc attaagggct tggattataa atggtctgaa
      901 aatactagta ttaaggaagc gttaaatgag tagaaatcag gactgtaaga atattctaat
      961 cattggtttt ggaaaaattg ggaaaattaa agcgtacaag tggctatcac gcggatatga
     1021 ggtatatgtc aaagatttga aattctccag catgaaatac cttaatacaa atagtgatgt
     1081 gttggatgat ttatcacgac aatattttac tattgagatt tgtactccga caaatcacca
     1141 ccttacgcta ttgaaaaccg ttataacaag gtatgtctat tcttatatta gcattgaaaa
     1201 accactgtgt aacaggttag aagatttaga agaaatgaag tcgctagtag aaagtcaccc
     1261 acatctagca aaaaaaatgt ttgccagtga acaatacttc ttttcgaaaa ttttggaaaa
     1321 actgttacaa gtagattgtt tctctctaga taaaatcaag gaaataacag ttaatttttc
     1381 taaagatagg attgaggata acgagaatgg gagattttta gataaagaga tattgggcta
     1441 tggaatagag attcctcata tcattgctgt catttcttat ttaggaattt cattagaaga
     1501 attcaaaaaa ggaatctttg tgaatgctat ttatataaaa gacttagaga aacacgatta
     1561 ttcaatagaa atattatctt gtattaatca aacagtgatt aaaattatta gtaatttggg
     1621 aagttttgca ataagagagg gcaagattga aggaggtgat gctaaaacag taagaagagt
     1681 taccattgat gacaaaacaa tactatttga tccacatcct aaactcgaga ggtataagag
     1741 tgaattggtg actgggacaa atacgtttca aatacacgat gatatgatgg atacgtatat
     1801 cagtttgtta gaaggaaatg ctattcctga agattgctat atcaataatg caattgagat
     1861 aacaaaatta ttaattaact tatattcaga atgtgaaaaa atttatttat gaggtgtaac
     1921 tatggattta aaaattacaa acggctttta tgacccaagt catttatcat acgaagtagt
     1981 agaacgcaaa ggcttaggtc accctgatac cttagcagat ggaattgctg agcaaattga
     2041 aattgattac tcactttatt gtttggacaa gtttggtgtt attccacatc ataattttga
     2101 taaaattatt atccgagggg gacattcagt tcaggatttt ggtggaagtg actttattga
     2161 accaattaaa attatttttc taggtagggc gagcaaaaaa tgttttaata gttcaattcc
     2221 actttttaaa attcagaaaa aggctgcaac taaatattta aatagaattt tacctaattt
     2281 agatgttgaa aattatgtag aatttgagac attgacctca gattttacta caaaaactaa
     2341 ttggttctcg cctgaagcaa tagaagattt accggagtat ctagatgtac caaaggcaaa
     2401 tgatacagct acaatgataa gttattggcc attaacaatt tctgaagaat tagcattaat
     2461 ga
//
LOCUS       DAUGSW010000078         2344 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUGSW010000078 DAUGSW010000000
VERSION     DAUGSW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2344
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.078"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            52..207
                     /locus_tag="VIB18_001606"
     CDS             52..207
                     /locus_tag="VIB18_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEQ8766587.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            291..1916
                     /locus_tag="VIB18_001607"
     CDS             291..1916
                     /locus_tag="VIB18_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEQ8766588.1"
                     /translation="MIKRDELKLEYQNHQFYEYVNSIFDYDILDTSIRETSEVLRKKT
                     HKLFYSEFENQLFETIMFLSMKTLVLDINPFSKEIENKSEAYEQCIQQIREENGINHF
                     FDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIRSCFNISESLSNVAFSLGDSHS
                     KKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNIPSFSLPKSLVKADYCWQL
                     GVAYTSSNKDEVVKIYFKYGVLAAFSEIFSITDLHMENVIVSGGDLYLIDVETFFQRK
                     LNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNSAPNVSGISGKGGKRKKGKYEL
                     INKNRGDMKLVKVDYFQEDGFNIPTLNGKVVEPLDYANEIISGFRECYIFLLSQRSKI
                     KGIVEGFPELKSRALFRNTSDYGKFLQDSTNPKYLFSEKKRKNLFSILYDAKHIEHFI
                     VNNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNLGDTTSLFDSITILNDERLKFTCE
                     LLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            1918..>2344
                     /locus_tag="VIB18_001608"
     CDS             1918..>2344
                     /locus_tag="VIB18_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8766589.1"
                     /translation="MDKTDFKNISAFVSQDSPIFDGDVMYNISLGRESVSGEQVIETC
                     KRVSIYDDIMSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRVLVTHRLNTVEKADKILIMDNG"
BASE COUNT          851 a          309 c          441 g          743 t
ORIGIN      
        1 atttacaata aaagtgtaga aaatagtcac tacatactga tagaaaggag aatgagtttt
       61 atgaaaaatt caaaggatat tttgactaat gctatcgaag aagtttctga aaaagaactt
      121 atggaagtag ctggtggtaa aaaaggttcc ggttggtttg caactattac tgatgactgt
      181 ccgaactcag tatttgtttg ttgttaatta aaacaatctg gacaagcaga ctaaaaattt
      241 cctgtttaga ctcagtctag gcaggatttt tgagtagtgg taggaaaaaa atgataaaaa
      301 gagatgaatt aaagttagaa tatcagaacc atcagtttta cgaatacgtt aactcaattt
      361 ttgactatga catattagat acttctatta gagaaaccag tgaagtgtta aggaaaaaga
      421 cacataagtt attttatagt gagtttgaaa atcagttatt tgaaacgatc atgttccttt
      481 cgatgaaaac actagtttta gatataaatc ctttttccaa ggaaattgaa aataagtcag
      541 aggcatatga gcagtgtata cagcagataa gagaagaaaa cggaataaat catttttttg
      601 acaggtatcc gtatttgcta aaacaaatta ataaagaagt aggactgata gaggaatcat
      661 attctttatt atttgataga tttttagaag acttatctga gataaggtcg tgctttaaca
      721 ttagtgagtc cctaagcaat gttgcctttt cacttggtga cagtcactct aaaaagcaaa
      781 cagtcgttaa aattgcgttt aaagagaaat ctgtttacta caagcctaaa agttatcatt
      841 cacacagtat cttgttagaa cttactagtt tattgaaatc tagtaatata ccctcattca
      901 gtcttcctaa aagcttagtt aaagcagatt attgttggca acttggtgta gcttatacaa
      961 gttccaataa agatgaagta gtgaaaattt actttaagta tggtgtttta gcagcatttt
     1021 ctgaaatatt ttctattacg gacctacata tggaaaatgt gattgtttca ggcggagatt
     1081 tatatttaat tgacgttgaa acattttttc aaagaaagtt gaatgtacaa aatcagaatt
     1141 ttgaagggat tactgtagac acctatcaga gaatttatga gacatcactt tcaaacggtt
     1201 tatttcctgt acaatttgag aaaaacagcg ctcctaacgt ttctggaata agtggaaaag
     1261 gtggaaaaag aaaaaaggga aagtatgaac tgataaataa aaatcgtgga gatatgaagt
     1321 tagtaaaagt tgactatttt caagaagatg ggttcaatat tcccacatta aatgggaaag
     1381 tggtagagcc tcttgactat gctaatgaga tcatttcagg atttagagag tgctacatat
     1441 ttcttctatc acaacgttca aagattaaag gaatagtaga aggttttcca gaattgaaaa
     1501 gcagagccct atttcgaaat acttccgact atggaaaatt tttgcaagat tctacgaatc
     1561 caaagtatct tttctcagaa aaaaagagga agaatttatt ttcgatacta tatgatgcaa
     1621 aacatattga acattttatt gttaataatg aaattaaaga tttgatgaat ggtgatattc
     1681 cttacttttc aatggatacc agaggaaacg tctataattc tgtagggaca ttaattggaa
     1741 atctaggaga tacaacctcg ttatttgata gtataactat tttgaacgat gaaagattga
     1801 agttcacttg tgaattgctt gaaatagtct tgaaaaaacc gattaagcat tgggagaggg
     1861 aaaagggcaa atcttatcag tttttatcaa tctcctcaga acattacctt ctctaaaatt
     1921 gataaaactg attttaagaa tatatcggct tttgtatctc aagattctcc aatatttgat
     1981 ggggatgtga tgtataacat ttcgctaggg agagaatctg tttcaggaga acaggttatt
     2041 gaaacttgta aaagggtatc aatatatgat gatatcatga gtatgccaat gaagtttcat
     2101 accccacttt ttcgagacaa tccatcacta tctggggggc aaaaacaacg aatttctcta
     2161 gcaagagagt tagtaactac ccctagaatc ttagttcttg atgaacctac atcagcttta
     2221 gatgtaaaaa ctgaaagaat aatccaaaaa aatgttgagg ctttacattg tacgagggtt
     2281 ttggttaccc atagacttaa tacagttgaa aaagctgata agattttaat aatggataat
     2341 ggga
//
LOCUS       DAUGSW010000079         2299 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUGSW010000079 DAUGSW010000000
VERSION     DAUGSW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2299
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.079"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..557
                     /locus_tag="VIB18_001609"
     CDS             <1..557
                     /locus_tag="VIB18_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8766590.1"
                     /translation="FFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARLLS
                     FTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNGTN
                     EKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQNDLK
                     NIQYDVTIGKGYLLKHKTFFKISR"
     gene            736..1431
                     /locus_tag="VIB18_001610"
     CDS             736..1431
                     /locus_tag="VIB18_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8766591.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            1433..1774
                     /locus_tag="VIB18_001611"
     CDS             1433..1774
                     /locus_tag="VIB18_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEQ8766592.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            1767..>2299
                     /locus_tag="VIB18_001612"
     CDS             1767..>2299
                     /locus_tag="VIB18_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEQ8766593.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVS"
BASE COUNT          762 a          341 c          399 g          797 t
ORIGIN      
        1 aatttttctc agttattaca atgcaaaatc atattccttg gtcatccgat tatcctgaag
       61 aaattgttgc tgaaggaaaa aatttcacgg aagaagaaaa tcacaaccta acaagttatg
      121 ctcggttatt atcgtttact gataaggaaa caagagcatt tttagaaaaa ttaacacaaa
      181 ttaacaagcc tatcacagtg gtgttttacg gagatcattt acccggttta tatcctgata
      241 gtgcttttaa caagcatatt gaaaataaat accttactga ttattttatt tggagtaatg
      301 gtactaacga gaaaaaaaat catccgctta tcaactcaag tgattttact gcagctttat
      361 ttgagcatac tgattcaaaa gtatcacctt actatgcttt gttaacagag gtactgaata
      421 aagctagtgt cgataaatca ccagatagtc ctgaagttaa agctattcag aatgatttaa
      481 aaaatatcca atacgatgtg actataggaa aaggttacct tttgaaacac aaaacttttt
      541 ttaagatatc acgttaagaa aaatgctatg ctgtccgagt atagacgagc atcaaggttt
      601 ggtaatttgc tcaaatgatt gtcaacagag tgtctaggac caggtttaaa agattataat
      661 tcttaaggtc ttattcgttt ataaaaaatg aatactcttt taaaatctta attgaaatga
      721 ataggagaag ttttcgtgaa aaagttaatc attattcctg cttacaatga aagcagtaat
      781 attgtcaata ctatacgtac tattgaatca gatgccccgg attttgacta tatcattatt
      841 gatgattgct caacggataa tacgttagca atatgtcaaa aacaggggtt caatgttatt
      901 tctttgccca ttaacctggg aattggcggt gcggtgcaaa ctggctatcg ttatgcacaa
      961 agatgtggat atgacgttgc agttcaagta gatggagatg gtcagcacaa tccatgttat
     1021 ttggaaaaaa tggttgaggt attagttcaa tcttcagtaa atatggtaat tggatcacga
     1081 tttatcacaa aagaagggtt tcagtcatca tttgctcgac gtatcggtat aaagtatttt
     1141 acttggctta ttgcgctact aacaggaaaa aaaataacag atgcaacgtc aggtctaagg
     1201 ttaattgacc gttcattgat tgaacgtttt gctaatcatt atccagatga ttatcctgaa
     1261 cctgaaacag ttgttgatgt attggttagt cattttaaag tgaaagaaat tcctgttgta
     1321 atgaatgagc gacaaggcgg tgtgtcatct atctcgttga cgaaatcggt ctattatatg
     1381 attaaagtga ctttagctat tttagttgtt agattgaaag gaaatcgtta aaatgacggt
     1441 aacagccagt ttatttataa gttttattgt attaaccttt gttttctttt tgattaactt
     1501 aatcaaaaaa gacaaactag cgattaagta ctctttattg tggtttattt tagctttatt
     1561 aattttacta tttacgtggt tacctaacat attaaataaa atgtctcact tcctgggtat
     1621 tcattcacca accaatatgt tattcttttt aggtttttgt ttgagtttag ctattatttt
     1681 ttcactgact aataatatct cacttcaaaa tgataaagta aaacgtctga cccaagaagt
     1741 ggcccttatg aaaaaagaga aaaccaatga ttaatccttc aaaacaaaac caaacgattt
     1801 ttttatggaa tatgttagga agtttatcaa cagctgtaat atcagttata ttacttatgg
     1861 tggttactag gttactaact tcggctgatt cagatattta cgcctttgcc tattcttttg
     1921 ctaatatgat ggtagttgtt ggactttttc aggttcgtaa ttatcaagca acagatatta
     1981 atgaaaaata ttcctttagt cagtacttag tggcaagact gatgacttgt ttattaatgt
     2041 tagccataac agtaatttat ttaacgttaa ctaagacaga tagctacaag agtacaattg
     2101 tctttctagt ctgtttctat agatcgacag atgctttttc ggatttatat cagggaatgt
     2161 tccaacaaca tgaacggctg gatattgcag gtaaatcgct agcctacaga aatactctta
     2221 tttttatggt gtacacagca ataatattat attccaaaaa tcttacttta gcattagtag
     2281 ctgtctgtat agtttcatt
//
LOCUS       DAUGSW010000080         1963 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUGSW010000080 DAUGSW010000000
VERSION     DAUGSW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.080"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..845
                     /locus_tag="VIB18_001613"
     CDS             <1..845
                     /locus_tag="VIB18_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8766594.1"
                     /translation="PPLMPELDGQEVPEVPSESLEPALPPLMPELDGQEVPEKPSVDL
                     PIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQNPVDIDKKLPNETGFSGNMVETE
                     DTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVETEDTKEPGVLMGGQSESVEFTKD
                     TQTGMSGQTAPQVETEDTKEPGVLMGGQSESVEFTKDTQTGMSGFSETVTIVEDTRPK
                     LVFHFDNNEPKVEENREKPTKNIAPILPATGDIGNVLAFLGILILSVLSIFSLLKNKQ
                     NNKV"
     gene            1642..1782
                     /locus_tag="VIB18_001614"
                     /pseudo
     CDS             1642..1782
                     /locus_tag="VIB18_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004224222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          682 a          346 c          443 g          492 t
ORIGIN      
        1 ttcccccatt gatgccagag ctagatggcc aagaagtccc agaagttcca agcgagagct
       61 tagaacctgc gcttccccca ttgatgccag agttagatgg tcaagaagtc cctgaaaaac
      121 ctagtgttga cttacctatt gaagttcctc gttatgagtt taacaataaa gaccagtcac
      181 ctctagcggg tgagtctggt gagacggagt atattaccga agtctatgga aatcaacaga
      241 accctgttga tattgataaa aaacttccga atgaaacagg tttttcagga aatatggttg
      301 agacagaaga tacgaaagag ccagaagtgt tgatgggagg tcaaagtgag tctgttgaat
      361 ttactaaaga cactcaaaca ggcatgagtg gtcaaacaac tcctcaggtt gagacagaag
      421 acacgaaaga gccaggagta ttgatgggag gtcaaagtga gtctgttgaa tttactaaag
      481 acactcaaac aggcatgagt ggtcaaacag ctcctcaggt tgagacagaa gatacgaaag
      541 agccaggagt attgatggga ggtcaaagtg agtctgttga atttactaaa gacactcaaa
      601 caggcatgag cggtttcagt gaaacagtga ccattgttga agatacgcgt ccgaagttag
      661 tgttccattt tgacaataat gagcccaaag tggaagagaa tcgggaaaag cctacaaaaa
      721 atatagcacc tatccttcct gcaacaggag atattggaaa tgttttggcc tttcttggaa
      781 tccttatttt gtcagtactt tctattttta gccttttaaa aaacaaacaa aacaataaag
      841 tctgacgtaa aagtgtttca taagaaataa tgcgcaaata tgctgaatag tggataactg
      901 ctacagtcaa gacaagtgtt aattcaaaag atactactta tacatctgat aataaggtga
      961 cagataattc agagcaagta gggtggctaa aaaatgatgt attctatgta taatagactt
     1021 acaagaaatc aagttattgt taaatgtcgt aaagcttaat gctttcaaaa gccgaagtca
     1081 atcgagactg tctttatgcg gtctcgattt ttaagtacga cgggcatatc ttacatctga
     1141 ggtgcaaatc cttcgtgaac acccgctacc ggtgaaccca atagcgactc ccaagtctga
     1201 ctatcgggag tagtggggag aggaagggat agtgaaatcg tggctctaca aacagaaacg
     1261 tgatatcaag gcgtatatag cggatgagtc taaagtccaa aaaagtagtc gtaacctata
     1321 ggcgtaaatc acgagagtaa acgaggaaag atgtacacct tatcctttga ggtctcatga
     1381 gcgttctaga cgtagtaaca acaaatgatg agaagtcagc cgatgccata gtagcgatga
     1441 aacttctgta atggaagtag agcgaagggc taaacaatta accgaagtat acctacttca
     1501 cttgtgtctg taaaactagt ggtctgatag aactgggtgc ggtcacgtat tgactagagg
     1561 aaagttcact aatataagat gtccctcaga caccaaaata agaaaggaat acgcaaagag
     1621 gggtggaaaa gtcgtccaca atcaagatgg agcgaccatt gtcaattagt agcttaaaag
     1681 tcagttttaa aacaagctat atcaaaaaca gtcctcgcaa aacggggact gttttcttac
     1741 ttggatgact acttagaacg acatgcgtta aaagttcatt gaaccgccgt gtgccgaacg
     1801 gtacgcacgg tggtgtgaga gtggctagaa attagcccct actcgatttc tatctaagct
     1861 aaaaatagaa atcaaattaa aagactagaa aataaatttc agagtgcttg gaaatatctc
     1921 caaataaaca tttttctcaa aaatgaggtt ttcatataag aaa
//
LOCUS       DAUGSW010000081         1957 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUGSW010000081 DAUGSW010000000
VERSION     DAUGSW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1957
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.081"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            127..768
                     /locus_tag="VIB18_001615"
     CDS             127..768
                     /locus_tag="VIB18_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEQ8766595.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEATPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPSDIENSKGR"
     gene            complement(815..1657)
                     /locus_tag="VIB18_001616"
     CDS             complement(815..1657)
                     /locus_tag="VIB18_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEQ8766596.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     IRDHFMENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVSVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKADWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAFVLFALGIWLGLWMSQLE
                     EKYK"
BASE COUNT          694 a          332 c          378 g          553 t
ORIGIN      
        1 atattttata tataaaaaaa taacatatat atcaaaaatc actaactagg agtaataagt
       61 tgaccaaaaa gctaggattg gttatgatga agataagatt aacggaaaga gaaattaggg
      121 aaggctatga aggacttatt aaaacagtat caggcaaaac cactaggaga ggagaagcgg
      181 tacgccgtat ttttacctct tattcttgtc aatgatgact ggcatgtctt atatgaagtc
      241 agaagtcagc atatttcaca accgggggaa gtttctttcc cagggggaca agtagaaaat
      301 caggagacac ttcaagaagc tgctatccga gaaacagttg aggaattgac tgttgatgcg
      361 tcccagatcc agctatgggg tgaaattgat tatttagtac agtcttctag aactattcat
      421 tgtttcgttg gtcaattagt cgttgatgac tggaaaagca tacagcctaa cgaagaagtt
      481 gacaaggtct ttatagtacc tttacgtcag ctacttttca ctgatcctgt ctattatcgt
      541 ttagaagcca ctcctattga gacaacggat tttccttttg accgtattcg taatgggaaa
      601 tactaccaat ttagtcaaga gtaccgtagt attccgtttt atgaaaatct agaagaaacc
      661 atatggggaa tgactgccca gtttactaag tgtttaaccg atattctaaa tgatgaatca
      721 attgcaaaga aaaacccctc agatattgaa aattctaagg ggagatagag cactagtttg
      781 ttggcgtcaa ctttttgtca acaaactgta aaggttattt gtatttttct tctaattgac
      841 tcatccaaag tccgagccaa ataccaagag caaataacac aaaggccata agccaggtta
      901 agatacctgc atgactgtag gaaatggatt cgggactact actatttgga ataagaatta
      961 atagcgtgct ggataataca ataccaatga taaagtggta aacttttgaa tgatggtgct
     1021 gtaaagcata atccatactt ttagaaaaag ccaagatggc taggactcct ccgatagcaa
     1081 taggtaagaa agtccctaat aaatccaaag atttgaaccc tattaacata ggaccataga
     1141 gtcctaagat aagtaagaga tttgacgggc ttagtccagg gaccagtact cctaaagcaa
     1201 ttaaggcacc tgctaaaata aaggttaaaa agttagctgg taaggtaccg attaagtcat
     1261 ttaagaagta aagacctagt cctgaaataa caaaggtaag gactagccat agccagtcag
     1321 ctttgtctct ttgagactgc ttggttgact ccttaatcag actaggaata gtgccgacaa
     1381 tagcgccagc aaatccccat aagacgctaa cttgatagtg cttaagcaaa aactcaacgg
     1441 ggaaagaaaa gagagcaata cctaaaatac caccaattcc tactggtaag aaaaataaga
     1501 cattttccat aaaatgatcg cgaatatgag ctaagaacga aatcatacgt tcgtagatac
     1561 caagaattgc tgctaagact cccccagata ccccaggtaa aataaaccca agcgcaataa
     1621 tcatcccctt aaagacgcga gaaataaacg aaaccataac tgcctcctaa aaatagttat
     1681 cttattgtat catattttta acagagcagc ggagtgaaaa ctgtaaggct ttgaaacgtt
     1741 gctttcatag gctttctaga cttttaaata ttaaagtggg ggtttctgaa tgtccaattt
     1801 ttatttttaa atcgattata tatataaaag tgttgaggta aagtaaaagg ttcatttgaa
     1861 attacataat agtttgcagt gttaattgtt gcttcattta aatatttaat attttctgaa
     1921 gtcagtataa ttagcatagt tctagtttta tcaatag
//
LOCUS       DAUGSW010000082         1866 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUGSW010000082 DAUGSW010000000
VERSION     DAUGSW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.082"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            313..546
                     /locus_tag="VIB18_001617"
                     /pseudo
     CDS             313..546
                     /locus_tag="VIB18_001617"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            755..1866
                     /locus_tag="VIB18_001618"
                     /pseudo
     CDS             755..1866
                     /locus_tag="VIB18_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT          560 a          383 c          388 g          535 t
ORIGIN      
        1 cgttcttcat gaactcgtcc caatcttgtt aatcaatgtt tccaagcgac tggtaagaat
       61 aaattatggc taggagactt aacctacatt cctacacaag aaggaatact ttatgtgtct
      121 gtcttgatag acgtttatag tagaaagatt gttggttggg caatgggcta acgtatgcaa
      181 gacaagttgg taacagaagc tttcaatcaa gcttataata tagaaaagcc taaagaaggg
      241 gtaatcgtcc atacagatca gggttctcaa tataccggag catgatttca ggacctactt
      301 agacagaaaa aatgtaagtc caggatgagt cgaaaaggta atccatacga taatgcactc
      361 atggaatcct tttataaaac attaaaaaga gagcttgtca atgatgctca tttcgcaact
      421 attgagcaag ctaagcttga gatttttaaa tatagtgaga cttactataa ccccaaacgt
      481 ctgcattcag ctttagggta tctctcacct gttgaatttg aaaaaaatag ttactcatta
      541 gcttaacttt atgtctattt tttcttgaca agtccaacat tcagcaagtg tctttagatg
      601 ctgctggttt tcaatgcctt acaggaggtg tacaagccac ccgttttcac gggtgctttc
      661 agactgaaga caaagtcctt agaatcgttt ttctaggggc ttttcatgat atttaggagt
      721 ataatataag aaaaaggact tgtgaggttc tcctatgtta cacaaagaaa aacctgatta
      781 taaccgcaat cagtacggtt tctataccct tgaccagtta gtgcctgatg aacatttcct
      841 gcgccaagtg gaagctgtga ttgacttcga cttcatctat gacctagtag aagacaccta
      901 ttcgtctgat aatggtcgcc ctagccttga tcctgtcatg ttggttaaaa tccctctgat
      961 tcagtgcttt tatggcattc gttccatgcg tcagaccatc aaggatattg aagtgaatac
     1021 tgcctatcgc tggtttttag gtttgacttt ggatgacaag gtgccacatt tcacaaccta
     1081 tggcaaaaat tattcccgtc gctttcaaga aaaaggcttg attgagtcca tttttacgca
     1141 tattcttggg ctatgtatca atacaggcct gattgacccg acgaagattt tcatagatgg
     1201 gactcatatg aaggctgcgg ctaataatcg caagttcatc aaccgagagg tggaaaaaca
     1261 agccaagttc atgagtgaac agctagaaat cgaaatcaat cgggataggg agaagcatgg
     1321 aaaaaagccg ctagggcccg ccaaagagct agagcccgtc gctaagaaaa tctccacaac
     1381 cgatccagaa agtggctggt ttcacaaatc ataaggaagt cttcgcttat tctgctcagg
     1441 tggcttgtga caagtatgga tgggcgcttg cttatagtgt tgaggctggc aatatccatg
     1501 atagtcaggc ttttcctgca ctttttgcca agcttgaacc cttgaaacca cagtttatta
     1561 ttgcggattc cggctataac attcccagca ttgccaagtt tctgattgat aaggggatca
     1621 ctcctgtcct tccttacaca cgaccaagag gaaagaaaga ccttctacgt ccgaaagaat
     1681 tgatttatga tgagcacttt gattgtgtca tctgccctga acatcaagcc ttgacctacc
     1741 gcactacgac cagagaaggc taccgagaat acaaaagtga ccctgtaatt tgtgccaatt
     1801 gtcccctgtt atctgtatgt acgaccagta agaaccacca aaaagttatc acacggcata
     1861 tttgga
//
LOCUS       DAUGSW010000083         1855 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUGSW010000083 DAUGSW010000000
VERSION     DAUGSW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.083"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..270
                     /locus_tag="VIB18_001619"
     CDS             <1..270
                     /locus_tag="VIB18_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin carboxylase"
                     /protein_id="HEQ8766597.1"
                     /translation="LNTDTNKFSGIVFFGLNPENYGKIFNGVSYDAPKTSLIFEEKIY
                     KKEGTVLPNPINWSNERVGYVCLENKEYAVLEKEMKEILKSLSIE"
     gene            195..1214
                     /locus_tag="VIB18_001620"
     CDS             195..1214
                     /locus_tag="VIB18_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEQ8766598.1"
                     /translation="MFGKQGIRCARKGDERNIKIIVNRVNSERNIKSIGICSPSYPGT
                     FHYQKRYKRGVEFLQNKGFTIVEGNLTGKEGYRGEISGGVQDRAEELNQLIPRVDVIM
                     TSIGGYNSNSVLKYIDYDLFKQKSPIFIGYSDTTALALALYKKTGCITYLSQSVISNF
                     GEFEPFNELNYFYFDFMLQSKCETLMVQIPDVWTDEWINWETYERTKKTNKNEWIIFN
                     KGEFNGTLIGGNLDTIVGIIGTEYMPKITEDTILLLEDVYTDLGRLYRNFTTLALHGI
                     FDKIGGLIISKFETIGENSDVINDIINEFVGHRKIPILLNFDCGHTHPSCLMPIGGKI
                     TLSLS"
     gene            1227..>1855
                     /locus_tag="VIB18_001621"
     CDS             1227..>1855
                     /locus_tag="VIB18_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HEQ8766599.1"
                     /translation="MNNRESKLTGFYDVFEEEVEKINHIHNVFVEESEKFGFQQMKTA
                     MVEHRKKYLDATDVHYTKIFEVHRVKEESVYALQSDLALSMSRCIANLPQQIPVKWIQ
                     EGVLFRDRIPTYKGYRRQFNQILLGAWGIESAYVDAEIIVATWRGLQRFKGIKVEFIQ
                     LSNKNIFDVLEKDLSKKLRFEDISIEAILGKYLCNNDIEIIKCLYEKDK"
BASE COUNT          703 a          218 c          367 g          567 t
ORIGIN      
        1 ttaaatacag acactaataa gttttcagga attgtatttt tcggactcaa tccagagaat
       61 tacggaaaaa tatttaatgg agtgagttac gatgcaccta aaacttcact aatatttgaa
      121 gaaaagatat ataaaaagga aggaactgta ttgccaaatc cgattaattg gagtaatgag
      181 agagtaggat atgtctgttt ggaaaacaag gaatacgctg tgctagaaaa ggagatgaaa
      241 gaaatattaa aatcattgtc aatagagtaa atagtgaaag aaacatcaaa tctataggta
      301 tttgttcacc ctcctatccg gggacatttc attatcagaa acgatataag agaggagtag
      361 aatttttaca aaataaagga tttactatag tagagggaaa tttaacagga aaagaaggtt
      421 atagagggga aatttcagga ggagttcaag acagagctga agaattaaat caacttattc
      481 cgcgtgtgga tgtcatcatg acttccatag gtggctacaa ttctaattct gtattaaagt
      541 atatagacta cgatctattt aaacagaaat ctcctatctt tattggatat tctgacacaa
      601 cagctcttgc tttagcctta tataaaaaga ctggatgtat aacttacctg tctcagagcg
      661 ttatctctaa ttttggagag tttgaaccgt ttaatgaatt aaattatttc tattttgact
      721 tcatgcttca gagtaagtgc gaaaccttaa tggtacaaat accagatgtt tggacggatg
      781 agtggataaa ttgggaaacc tatgaaagaa ccaaaaaaac aaataaaaat gagtggatta
      841 tttttaacaa aggtgaattt aatggtactt tgatcggagg aaatctcgat accattgtag
      901 gaataatagg aactgagtat atgccaaaaa taacagagga taccatactc ttgttagaag
      961 atgtatatac ggatctagga agactatata ggaatttcac aacgcttgcc ttacatggta
     1021 tttttgataa aataggagga cttattattt caaaatttga aacaataggg gaaaatagcg
     1081 atgttattaa tgatatcatt aatgaatttg tagggcatag aaagattcct attttattga
     1141 attttgattg tggtcatact catcctagct gtttaatgcc tattggtggt aaaattacgt
     1201 tgagtttaag ctaaaagagg tggtatatga acaatagaga aagtaaatta acgggtttct
     1261 atgatgtttt tgaggaagaa gtagaaaaaa taaatcatat tcataatgtt tttgtagagg
     1321 agtcagaaaa atttggcttt caacagatga agactgctat ggtagagcat agaaaaaaat
     1381 acttagatgc aaccgatgtt cattatacaa aaatatttga agttcataga gtaaaagaag
     1441 agtcagtata cgccctccaa tcagatttgg cacttagtat gtcgcgttgt atagctaact
     1501 taccacaaca aatacctgta aagtggattc aagagggagt gttatttaga gatagaattc
     1561 ctacatataa aggttataga agacaattta atcaaatatt attaggtgca tggggaatag
     1621 aatcagctta tgtggatgca gaaataatag ttgcaacttg gcgaggcttg cagcgattta
     1681 aaggaattaa agtagaattt attcaactgt ctaacaaaaa tatatttgat gttttggaga
     1741 aagatttatc taaaaagtta agatttgaag atatttcaat tgaagcaata ttgggtaaat
     1801 atttgtgtaa taatgacata gaaatcataa aatgtcttta tgaaaaagat aaaat
//
LOCUS       DAUGSW010000084         1752 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.084, whole genome shotgun sequence.
ACCESSION   DAUGSW010000084 DAUGSW010000000
VERSION     DAUGSW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1752
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.084"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..819
                     /locus_tag="VIB18_001622"
     CDS             <1..819
                     /locus_tag="VIB18_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ8766600.1"
                     /translation="INSNQQFIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLI
                     EHSDTLLIHAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSN
                     SGILLTYAGTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGI
                     RTCNFSTEISKIYYIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNG
                     KYFSTMPLINYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            874..>1752
                     /locus_tag="VIB18_001623"
     CDS             874..>1752
                     /locus_tag="VIB18_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8766601.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLITDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKEIDLQSKIHKKSFEKIEKI
                     FLEVSQSFFETINDNSLNQDKLRLNINFESHSRQFIKSSDILSSNDIENLKLRALFLL
                     QEEKQYLHGLSEVEWDG"
BASE COUNT          651 a          205 c          320 g          576 t
ORIGIN      
        1 attaacagca atcagcaatt tatagaatat gatggcaatg gaaatatttt agtttatgga
       61 agattaaagt attttaaaga aggaatttca ttatactaca ttggagagta cttagctgaa
      121 tgtctcttga ttgaacatag tgacacctta ttaattcatg cagcagcagt ttataatcct
      181 ttatctggcc attcaatttt actattagga gataaaggtg ctggaaaaac tacggttgca
      241 ataaggcttt gtatagaaca tgggtatcac cttattggta atgaccaagt aatatttggt
      301 tcgaactctg gaatactact aacttatgca gggacatctt tctttaaaat aagaaggaca
      361 gctgttttgt cggacaattt actgtttaaa ttatttagca aattttttaa ccgttcatta
      421 caatttaata aggcaagttg ggatgataaa atttcaattt tcccaaagga gttgggaata
      481 cgaacttgta atttttctac tgaaatctca aaaatttatt atataaagac agacaagaaa
      541 gaaaagcaaa tttatcattc aatttggagt gatagtttag caagtttata tctaaatgag
      601 ctattgggaa ggcatatttc tggacaggtt gcatgttttc aatcagataa tggaaaatat
      661 ttttctacaa tgcctttgat aaattatgaa aaaaataatc gggtacgaga acagatagtg
      721 aagggtattt ttgctaaaca aaaattattt aaaattacag cagctacgcc agctaagatt
      781 gcagaagcga ttatagaaaa tgttaagaaa aactcatagt gtgggtgaat ttggggatta
      841 atatgaagta ttgaaaaagg agtaagagta attatgtttg tgataggcat tccaacttta
      901 aatgaggcag ataatatcag tagattagtt aaacaaattg atgagtatgc tgtaaattta
      961 gggaaagaaa ttattattat taattcggat agtaaaagta cagatggaac tccgcagatt
     1021 tttttagaaa ccaaaactta taacaccaaa gtttcgatag tatcagaagc taaaggaaaa
     1081 ggttataatg tgagaaatat tttcgaatat gcaataaatc atgtgccgaa tttctccggt
     1141 ttaattttga ttgatggaga cgttgtctca atgaaaaaaa tgtggttaga aaagatgttt
     1201 atagcaattg aatctggaaa tgatcttata atcccaaatt atgctagaaa atcttttgaa
     1261 ggaaatgcga caaaccattt tatttatccc atgttagtga aatttttcaa acgtgatatg
     1321 ccttatcaat gcatctctgg tgattttgga ttttcaagag gattgataac agatttaact
     1381 ttgaagtgta attggcacaa atatacatta ggttacggga tagatatttt tttaacctta
     1441 acagctatat taaagtcata caaaattaag gaaatcgatt tacaatcaaa gattcataaa
     1501 aaaagctttg agaaaattga aaaaattttt ttagaagttt cacaaagttt cttcgaaact
     1561 attaatgata attctttgaa tcaagataag ttacgtttaa atataaattt tgaaagtcat
     1621 tcaagacagt ttattaagtc cagtgatatc ctatccagca atgatatcga gaatttaaag
     1681 ttaagagcgt tgtttttatt acaggaagaa aaacagtatc tacatgggct gtcagaggta
     1741 gaatgggacg ga
//
LOCUS       DAUGSW010000085         1675 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUGSW010000085 DAUGSW010000000
VERSION     DAUGSW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.085"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..940
                     /locus_tag="VIB18_001624"
     CDS             <1..940
                     /locus_tag="VIB18_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8766602.1"
                     /translation="YLRNVSYNMLTFYILGIGTSISIVVALTRFVKEISLNFKEIKKL
                     ANKMGIEVLSENENYSKIIEFDDILRTLHIKGDNLKSLIEREILEKQDLSFQIAALSH
                     DIKTPLTVLKGNLELLELTTLNKNQEGYIVSMNNSISVFEGYFNSLISYTRMLSEDRS
                     VKLILVEKLLSELHFEVDDLLNINNIEFSICNRLIITSFYGDEENLIRALSNLLVNAI
                     RFMPVLDKKIEVILSESGEQIHFEIWNNGERFSDSTLKKGDKLFYTEDYSRGNKHYGI
                     GLAFVKGVAIKHGGNLQLNNPARGGASAIISIKKKI"
     gene            1097..1237
                     /locus_tag="VIB18_001625"
     CDS             1097..1237
                     /locus_tag="VIB18_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEQ8766603.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     VK"
     gene            1352..>1675
                     /locus_tag="VIB18_001626"
     CDS             1352..>1675
                     /locus_tag="VIB18_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8766604.1"
                     /translation="MIKAQLKNLIKTIHLVKEAGFSLNGSLYMELLYDFTHDELVHNP
                     IIESTVDTIQSVEFERVSFSYNGKDNVINDISFSIKAGERLAIVGGNGSGKSTIFKLA
                     CGLYDN"
BASE COUNT          600 a          201 c          307 g          567 t
ORIGIN      
        1 ttaccttaga aatgtttcat ataacatgtt gacattttat attctgggaa taggaacgag
       61 tatcagcatt gtagttgctt taacacggtt tgtaaaagaa atttctttga atttcaagga
      121 aatcaagaag ttagcaaata aaatggggat agaagtcctt tctgaaaatg aaaattattc
      181 taaaataatc gagtttgatg atatacttag aactttacat attaaaggtg ataatttgaa
      241 aagtttgatt gagcgagaaa tattggaaaa gcaagatcta tcctttcaaa ttgcagcact
      301 ttcgcatgat ataaaaacac ctttaacggt tttgaaagga aatcttgagt tattagaatt
      361 gactacttta aataaaaatc aggaaggtta tattgtatct atgaacaata gtatttctgt
      421 ttttgaaggc tatttcaatt ctttaatatc ttatacacgc atgctttcag aggatagatc
      481 agtgaaacta attttagttg agaagctatt aagtgagtta cattttgaag tcgatgactt
      541 attgaatatc aataatattg aattttctat ttgtaataga cttattatca cttcttttta
      601 tggagatgag gaaaatctga taagagctct ttctaacctt ttagttaatg caataagatt
      661 tatgcccgta ttagataaaa aaatcgaagt tatactgtct gagtcaggag agcaaattca
      721 ttttgaaata tggaataatg gtgagcgttt cagtgatagt acactgaaaa agggagataa
      781 attattttac acggaagatt atagcagagg taacaaacat tatggaatcg gtttggcatt
      841 tgttaaaggc gttgctatca aacacggtgg gaatcttcaa ttgaataatc cagctagagg
      901 aggtgctagc gccataatct cgataaaaaa gaaaatttaa tagatttgat tgaaactgga
      961 gtatttcagg caaaaaatcg taaatttttg tgatttttgg ctaaaatact ttttttctga
     1021 acaaattctg aacttggggt gtcataataa tcatgtaaat atatcggatg caaaaacgta
     1081 agagaggaac tagaaaatga ataacacaat taaagacttt gatctcgatt tgaaaacaaa
     1141 taaaaaagac actgctacac cttatgttgg tagccgttac ctatgtaccc ctggttcttg
     1201 ttggaaatta gtttgcttta caacaactgt taaataataa agttatcatt atcatcaaca
     1261 ttataatttc aaataatttg atatatttat aaatttaggg gagtagactg attttagttt
     1321 gctcctttat tagtagataa ggaagttata catgattaaa gctcagctaa agaatctaat
     1381 aaaaacaatt catctcgtaa aagaggctgg tttctcccta aatggttcat tgtacatgga
     1441 gttattgtat gattttacgc atgatgagtt agtacataac cctataatcg aaagtacggt
     1501 tgatacaatt cagtcagttg aatttgaaag ggtttctttt tcatataatg gtaaggataa
     1561 tgtaataaac gatataagtt tttcaattaa agcaggagag aggttagcaa ttgttggtgg
     1621 aaatggttct ggaaaaagta cgattttcaa attagcctgc ggtctttacg ataat
//
LOCUS       DAUGSW010000086         1637 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUGSW010000086 DAUGSW010000000
VERSION     DAUGSW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.086"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            18..938
                     /locus_tag="VIB18_001627"
     CDS             18..938
                     /locus_tag="VIB18_001627"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEQ8766605.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            992..1240
                     /locus_tag="VIB18_001628"
     CDS             992..1240
                     /locus_tag="VIB18_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEQ8766606.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(1365..>1637)
                     /locus_tag="VIB18_001629"
     CDS             complement(1365..>1637)
                     /locus_tag="VIB18_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8766607.1"
                     /translation="YTDKNGIIEIIAKTTDKNLLISVIDNGPGITDEEKKKIFDRFYR
                     VDKARTRQTGGFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
BASE COUNT          571 a          305 c          231 g          530 t
ORIGIN      
        1 aatgattagg agctaccatg tcaaatgaat ttattaactt tgaaaaaatt tctagagagt
       61 cttggaaaac attacatcaa aaggcaaaag ctctcctcac acaagaggaa cttaaaagta
      121 ttactagctt aaatgataac atcagtatta acgatgtcat tgatatctac cttccattaa
      181 ttaatctgat ccaggtttac aaaattgcgc aagaaaatct ttctttttct aaaagccttt
      241 ttctaaaaaa agacattcaa ttaagacctt ttattattgg aatttctggt tcagtagctg
      301 ttggtaaatc aacaactagt cgtcttttac aacttttatt atcacgaacg caccccaata
      361 gtcaagtcga actggtaacg actgatggtt ttttatatcc taatcagttt cttattgaac
      421 aaggactgtt aaatcgtaaa ggatttccag aatcttataa catggaactt ctcttagatt
      481 ttctagattc catcaaaaat ggtcaaactg cttttgcacc cgtctattct catgatattt
      541 acgatattat cccaaatcaa aaacaatcat ttaataaccc tgacttcctt atcgtcgaag
      601 gtattaatgt ttttcaaaat caacaaaaca atcgtttata tatgagtgat tactttgatt
      661 tttctattta tattgatgca gacagcagtc acatcgaaac ctggtacatt gaacggtttc
      721 taagcatttt aaaattagca aaacgtgacc ctcataatta ttatgcccaa tatgcacaat
      781 tacctcgatc tgaggctata gcatttgcgc gtaacgtttg gaaaaccgtt aatttagaaa
      841 atcttgaaaa attcattgaa cctacacgta accgtgctga attaatttta cataaaagtg
      901 ctgatcataa aattgatgaa atttacctca aaaagtgata aagggttgcc aaacgcatat
      961 attttctata taataatgta gttagattaa tttggaggtg aaaacattgg caaatattaa
     1021 atcagctatt aaacgcgctg aacttaacgt taaagcaaac gaaaaaaact cagcacaaaa
     1081 atcagctatg cgtactgcta tcaaagcatt tgaagctaac ccatctgaag agcttttccg
     1141 cgctgcttct tcaagcatcg ataaagctga atcaaaaggt ttgattcaca aaaacaaagc
     1201 aagccgcgat aaagcacgcc ttgctgcaaa acttggctaa taaatatcca atgaaaactc
     1261 cagctggagt ttttttatac ggtaaaaact caaaaaatac aataaagcgt tgacagttaa
     1321 aaataacttt aaaagggctg accttattgg tcgccctttt tagcttatag tttgacttca
     1381 aaaatactac ctttaggatc attatccttt actgtaatat ttccttttaa agacatcacg
     1441 atttgctgag ctaaagccaa ccccaagcca aatccacctg tttgccgtgt tctagctttg
     1501 tcaactcgat aaaaacgatc aaaaatcttt ttcttttctt catctgttat ccctggacca
     1561 ttatcaataa cagaaattaa taaatttttg tccgttgttt tcgctataat ttcaataata
     1621 ccatttttat ctgtata
//
LOCUS       DAUGSW010000087         1425 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUGSW010000087 DAUGSW010000000
VERSION     DAUGSW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.087"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            26..>1425
                     /locus_tag="VIB18_001630"
     CDS             26..>1425
                     /locus_tag="VIB18_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8766608.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLIFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENKECF"
BASE COUNT          424 a          217 c          253 g          531 t
ORIGIN      
        1 atcatttact atagaaggtg ataacatgac tatttttcgt aaaaaaaaga aatattccaa
       61 taaaacagaa atgcaaaggc acttcaaagt tattgattta atttttttag gcctaggttc
      121 aatggttgga acaggtatct ttacagttac tggcataggc gctgctaagt atgcaggtcc
      181 tgctttaaca atatcgatta tcatttccgc gattgctatt ggaattttag ccttatttta
      241 tgcagaattt gcgtctcgta tgccttctaa cggtggtgct tatagttatg tttatgcaac
      301 cttgggagag tttccagcat ggcttgttgg ctggtatatt attatggaat ttttaacagc
      361 tatatctagt gttgctgttg gctggggaag ttatttaaaa ggattacttg ccaattataa
      421 tatagtatta ccaaacgctt taaatggcac gttcaatctt aagaatggaa cttacataga
      481 tattcttcct gttttagtga tgtttttcgt gacagggatt gtcctaatga attcgaaatt
      541 agccctgaga ttcaatagtt ttttagttat tttaaaattt tcagcactgg ctttatttat
      601 ctttgtaggc atttttttta ttgatcacaa taattggtct cattttgctc catatggtgt
      661 aggacaaatt actggaggta aaacaggtat atttgctggt gcttctgtta tgttctttgc
      721 atttttagga tttgaatcta tttcaatggc agttgatgaa gtgaaagaac cacaaaaaac
      781 aatccctaaa ggcatcattt tatctttgat tattgtaaca gcactctata tagttgtcac
      841 cactatttta acgggaattg tacactacac taaattaaat gttccagacg cggtggcttt
      901 tgctttaaga aatattagac tttattgggc agctgactat gtgtcgatag ttgctatttt
      961 gactcttatt acggtatgta tttctatgac ctatgcatta gctagaacaa tttacagtat
     1021 tagtagagat ggtttattac ctaaatcact ttatactctc actaaaaaaa ataaagtgcc
     1081 tcaaaatgct actcttgtca ctggactact tgctatgatt tgtgcgggaa tatttccttt
     1141 atcgagtcta gcagagtttg ttaatatttg tactttagca tatttaatta ttctgtcggg
     1201 tgcaattatt aaactcagaa gaatagaagg agaaccaaaa gcaaatgaat ttaaaactcc
     1261 tctagtacca ttcctaccaa tgttggcaat tatcatttgt ctatcattta tgagccaata
     1321 taaagctttt acttggattg cttttgctat tgccacaatt attgggacat taatctactt
     1381 agcttatggt tatactcatt caatagaaaa taaagaatgt tttga
//
LOCUS       DAUGSW010000088         1382 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUGSW010000088 DAUGSW010000000
VERSION     DAUGSW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1382
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.088"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(81..1202)
                     /gene="mnmA"
                     /locus_tag="VIB18_001631"
     CDS             complement(81..1202)
                     /gene="mnmA"
                     /locus_tag="VIB18_001631"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEQ8766609.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVTVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          420 a          303 c          236 g          423 t
ORIGIN      
        1 attggttttt ataaataata tcatatgatg tcaaaggaat tgttgaatgt ccctttcttt
       61 ttatcttaat aaaaggttca ttaaatgtac tgacaaggct gcccattttt ataagccatg
      121 tcaatcatac caccaccaag gcattctttt ccgtcataga aaacaacagc ttgaccagga
      181 gtaatcgcgc gctgtggctc tgcaaaaaca acttctgcct tatctcctcg aacatgcacc
      241 gtcacgtgtg aatcgggttg acgatagcga aatttagcag tacattcaaa tgtgaactct
      301 tctggcatct cacgtgtaaa atggatgact gaggcgtcaa gactatttga cattagggct
      361 tcatggtaga aaccttgacc aacgtataaa atattttgcg acaaatcttt accgacaaca
      421 aaccaaggtt gattatcccc accatgctga ccaccaatgc ccagaccacc acgctgacca
      481 atagtataat acataaggcc ggcatgttct cccatatcgc gaccatcaat agtcatcatg
      541 cgaccttttt gtgccggtaa gtactggctc aaaaactgtt tgaaattctt ttcaccaata
      601 aaacaaatac ctgttgaatc tttcttttta gccgttgcaa gccctgctcg ctcagcgatt
      661 tctctaactt ctgacttttg caaatgacca agggggaata aagtcttttg tagttgttcc
      721 tgtgatagtt gacttaaaaa gtaggtttgg tctttgccat tatcagctcc acgtaacatg
      781 tgaaccgtac cattttcatc acgcttgact tgagcatagt gtcccgttgc tacataatct
      841 gcacctaaag tcatggcata gtcaaggaaa gctttaaatt ttatttcctt attacacatg
      901 acatcgggat ttggagtacg acctgctcgg tattcggcca agaaatattc aaatactctg
      961 tcccaatatt ctttttcaaa attgactgaa tagtaaggaa taccgatttg atcagcaacg
     1021 gctgctacat ctttgtaatc ttcagtagct gtgcaaacac caaattcatc tgtatcgtcc
     1081 cagtttttca tgaagacacc aataacatca taaccttgct cctttaaaag tagagctgtt
     1141 acagatgaat caacgccacc actcatacca acgacaacac gtatctttga gttatctgtc
     1201 ataaaaaatt ctcccatcaa taataagata gaaaaagata atcatcatat tatgaatatt
     1261 atgattcttt ttcttatcag ttaacgtacg attgaaggtc gtcgttttca aaagtcgatt
     1321 tgaaggtcga ttttgaagcg ccatcagcgc aaaccttatt ataacaatta ctgcgtggaa
     1381 tg
//
LOCUS       DAUGSW010000089         1328 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUGSW010000089 DAUGSW010000000
VERSION     DAUGSW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1328
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.089"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..295)
                     /locus_tag="VIB18_001632"
     CDS             complement(<1..295)
                     /locus_tag="VIB18_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HEQ8766610.1"
                     /translation="MVQIFLSNLFKIKNTSISKLILIFPIICVMLSLLFSALGGESIL
                     RLAAETTVNQWGVIWINVIIAVNSGLLNKLELDSNKYSVFLSRDVDLKKVEYAR"
     gene            complement(301..990)
                     /locus_tag="VIB18_001633"
     CDS             complement(301..990)
                     /locus_tag="VIB18_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8766611.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIVLEKEYDGSENLEEL
                     FNNQILFEKRR"
BASE COUNT          442 a          257 c          154 g          475 t
ORIGIN      
        1 ctctggcata ttctaccttt tttaaatcaa catcccttga taaaaaaaca gaatacttat
       61 tagaatctaa ttctaattta tttaacaaac cagaatttac agcaataata acattaatcc
      121 aaataactcc ccactgattt actgttgttt ccgcagctaa acgtaggata ctttcgccac
      181 ctaatgctga aaacaataaa gataacatca cacaaataat aggaaaaata agaatcaact
      241 tgctaatact cgtatttttt attttaaata aatttgataa aaaaatttgt accatagccc
      301 ctacctcctc ttttcaaata aaatttgatt attgaataac tcttcaagat tctcagagcc
      361 gtcatattct ttttccagaa caatctttcc ttcatagata aatccaataa aatcagctag
      421 atgttcaact tctgacagta tatggcttga aatcataatt gtcattcctt ctgatttaaa
      481 tgactctata atttccctta attcttgaat tccaattggg tccaagccat tagtaggttc
      541 gtctaatata agtaatttag gtgaatttat taaagagata gctataccta accgttgctt
      601 cattccaaga gaaaattgtt ttactggtct cttgtcaata tttcctagac caactttatt
      661 taataatgga agtatagtgc tttctgaaac accaagcatt gttgtaacta ccttcatatt
      721 atcgtaagca ctcaaatttt tataaagtgg tggttcttca ataatacttc cgatttttcg
      781 cagatcccga cgtgaccatt ctctaccttc aaaaataata gaaccacttg tcttactaac
      841 taagcctgtc aaaattttca taatagttga ttttccagca ccatttggac cgattaaagc
      901 atacactttt cccttaggaa tattcatatt gacattattc aatatggttc tcttaccata
      961 agattttttt agattttgta ttttcaacat attagttact cccattctat atattgctga
     1021 gcgtttagtg tatagtgtat agtaagcaaa acaatacact ttctcttcaa actctctatc
     1081 aatcccgttt aatcgattca tcgatagttg taaaatgaaa cttaccatca ctatatctta
     1141 tataaatatc ctccaatcgc agttcgttct ctgaatccca tgatgtggta aaaaatgaag
     1201 tattataagg ctcatcacta tataactttg ataattcacc caatccaaca ttttcacgca
     1261 gtgtcaattc atactttaaa aaatcttgga acaatgcgga tattctcttg tagtatgact
     1321 ttttctgt
//
LOCUS       DAUGSW010000090         1283 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUGSW010000090 DAUGSW010000000
VERSION     DAUGSW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.090"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            68..155
                     /locus_tag="VIB18_001634"
     tRNA            68..155
                     /locus_tag="VIB18_001634"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:102..104,aa:Ser,seq:gct)
     gene            complement(520..801)
                     /locus_tag="VIB18_001635"
     CDS             complement(520..801)
                     /locus_tag="VIB18_001635"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8766612.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
BASE COUNT          422 a          157 c          270 g          434 t
ORIGIN      
        1 tggttagagc gcacgcctga taagcgtgag gtcggtggtt cgagtccact cgtgcccata
       61 tatatttgga gaattactca agaggctgaa gaggacggtt tgctaaatcg ttaggtcggg
      121 taactggcgc aagggttcga atcccttatt ctccgttttg taaagatatt ttagttaata
      181 tgttaaatga aacatattaa aggatgaatt ataaataaag gggaaagaag acggttatcg
      241 tctttttttg taatcttcaa aaccaactaa atagaatatt taaatcgttc attatttcga
      301 taactaaaat gataggctct ttgactactg tagaggagta aaacgtttaa cttgatggct
      361 ttgataaggt tgttgactgt ttctaatttg gccttagagt agttgagttt aagtatattg
      421 ctaatcttgt tcttttctag atgttagtta tgggcgtacg aaaaattggg caataaagct
      481 attattgatg agcttccgtg aatcatgctg tatgagtttt cagtaaagtt tgagagttct
      541 atacgcgata ggttttatag cagaagtatt tatgattcgg atacgaaagc gagttatagc
      601 ttgtctaaga cgttggggga tatgaaaaca atcgaggata attttagcct gtagaaaaag
      661 catagtaatc tcatagtagt gggcactgag tatacctatg gtaataactt tgacatgcct
      721 tctcacctgt ctggtataat gaaagagatg attatgaatg ctttttgcgt ccccagcatt
      781 tacataattt aaaaccgtga tgctaaggtt ttagattcct aatgaaatta tactataatc
      841 ggattattct atatgagtct ttctgaaatg atagtttggt cgcttttcat tatagatcgt
      901 catatggaac tttttacata tgtttaaaaa gactctataa tctttgaggt ggatttacct
      961 actacagaaa gtatagaatt aaaagttgtg aaagtttgcg agtctttatg aattgtgatt
     1021 gagtgatgga atactaagat ttatagatga ccagttttcg atagttagct tataaaaaaa
     1081 caaggtctga ctatacttat attaataatg ataaggtcaa aaaagatgtc taatattcta
     1141 attggaaaat ggaaaggcat aaactgataa tagaaaatgt cattattgtg gataatattt
     1201 taggcgaaaa gaagttatta acctgtggat aagtaactaa aaattcattc taagaaggat
     1261 aaggtgtctg agtgaagata aac
//
LOCUS       DAUGSW010000091         1237 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUGSW010000091 DAUGSW010000000
VERSION     DAUGSW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.091"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            264..380
                     /locus_tag="VIB18_001636"
                     /pseudo
     CDS             264..380
                     /locus_tag="VIB18_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611996.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(566..>1237)
                     /locus_tag="VIB18_001637"
     CDS             complement(566..>1237)
                     /locus_tag="VIB18_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ8766613.1"
                     /translation="KAYRPGEGVKARKEAAKANLEKVAKETKALISGDRYLSETEKAV
                     QKQAVEQALAKALGQVEAAKTVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAALNEA
                     KQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIASVK
                     EAKDKGITAIRAAYVPNKAVAKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLYSKK
                     KESKD"
BASE COUNT          369 a          255 c          213 g          400 t
ORIGIN      
        1 atcaagtaga aatgtcttta ttaagcgaat caatcaaggt tgtagagtaa atactggact
       61 agatttcatg tagaaattag taaaagttag gagatttttt ggtcgtttca aacgataaca
      121 tcatcttctt ataacaagaa cttcactcag agataaacta ttctaatact ttagtagcct
      181 cttttgagct tgtagcacga aaattcgctc gaactgattt aaaataggca ttttatctgc
      241 tcgcttgatc cctactgcgc aaccaagaaa ccttttattc actagaacaa ttaaccctta
      301 aaaccaagga ggaagtccac tggtggaact accatcacct tcacagtaat cttaattatc
      361 aaacacccat aactaaatga gtcatcgttt gaacaaaaaa cgccttataa attctgtaca
      421 gaaaactgtt gccttttcaa ttgaactttg aaatgttttc aatacactcc gttcttgggc
      481 ccttacgatc caaaaaacca aggtgatttc aaaatcacct tggtttgaaa atatagtaga
      541 aagcaatttg gataaagcca ggttcttagt ctttactttc ttttttcttg ctataaagca
      601 ccatacctaa aagaagagac ataactccta agccaacaag aacaattgag tttgcatcac
      661 ctgattttgg aagatggttc gctgacgatg attttgcgac tgccttatta ggcacatagg
      721 ctgcacggat agcagtaata cctttatctt ttgcttcttt cacagacgca atagattgtg
      781 ctgaacgaac agtcgcaata gccgtcttaa gcgctaatga tacattttct gattgttcag
      841 ctttttgagc ttcagtcaat ttagcatcag ttgtaatctt agcaagtgtt tctgccgcag
      901 cttgtttaag agcttcaata gcagcttgtt tcgcttcgtt aagagcagct gttgcttgat
      961 cagtatcttt agctaaacca gcaacatatg ctgaacggat agctacagta ccaaggtttt
     1021 ctgccaactt aacagcttca actgtcttag cagcctcaac ttgaccaagt gctttcgcaa
     1081 gagcttgctc aacagcttgt ttttggactg ctttttcagt ttcgctcaag taacggtctc
     1141 ctgaaataag agctttagtt tctttagcta ctttttcaag attagcttta gcagcttctt
     1201 tacgtgcttt aacaccttca cctggacggt aagcttt
//
LOCUS       DAUGSW010000092         1090 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUGSW010000092 DAUGSW010000000
VERSION     DAUGSW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.092"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(345..>1090)
                     /locus_tag="VIB18_001638"
     CDS             complement(345..>1090)
                     /locus_tag="VIB18_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8766614.1"
                     /translation="IFVLEDDFLHQTRIEKIIYKILTDNKLEVNHLEVYGKPNQLLED
                     ISERGRHQLFFLDIDIKGEDKKGMEIAVEIRNKDPHAVIVFVTTHSEFMPVSFQYQVS
                     ALDFIDKELPEELFSHRIEKAITYVQDNQGKTLAEDSFVFTNVKSQIQVSFSDLLYIE
                     TSLIPHKLILYSTKQRVEFYGQLSEIVEQDDRLFQCHRSFVVNPYNISSIDRSERLVY
                     LKGGLSCIVSRLKIRSLIKVVEELHTKEK"
BASE COUNT          404 a          189 c          152 g          345 t
ORIGIN      
        1 aaagaaatat taaaaacaat aaagtaaaca ataaaactat gaattacatc ccaaaaagca
       61 ataggaaaca aactataaaa taaaagaagt gaaccattga cctttcgtct tgcaatataa
      121 cgagtgtata acaaaaaaaa taatggataa agtaatagtc ctcctaaaaa acccactgat
      181 agtaggttgg ataaagaagt agataaaaga gaacagatat aaaatgttaa aatccctaat
      241 aagctctttt ttgtgtccat acgatagcca aatattctcg catgaattaa caatagcaca
      301 accacattaa gtgttatgac tatcgtatta attaaatata tcaactattt ctccttagtg
      361 tgcaactctt ctactacttt tattaatgat cgtattttca atctcgaaac aatacaagat
      421 aatcccccct ttaaataaac taaccgttcg gatctatcta ttgatgatat attataggga
      481 ttgacaacaa aggaacgatg acattgaaat aatcgatcat cttgctcaac aatttctgat
      541 aattggccat aaaattctac tctttgttta gtagaataga gaatgagttt atggggaatt
      601 agtgaggttt caatatacag caaatctgaa aaggagactt gtatctggga ctttacatta
      661 gtaaaaacaa atgaatcctc cgctaacgtt tttccttggt tatcttgtac ataagttata
      721 gctttttcaa tgcgatgact aaataactcc tctggcaact ctttgtcaat aaagtctaaa
      781 gctgaaacct ggtattgaaa agataccggc ataaattctg aatgtgtggt cacaaaaact
      841 atcactgcgt gcggatcttt atttctaatc tccacagcaa tttccattcc ttttttatct
      901 tctcccttaa tgtcaatgtc aagaaaaaaa agctgatgtc ttcctctctc tgatatatct
      961 tcaagcagct gattgggttt accataaact tccaagtggt taacctccaa cttattatca
     1021 gtcaaaatct tataaataat tttttcaatt ctggtttgat gtaaaaaatc gtcctctaag
     1081 acaaaaatat
//
LOCUS       DAUGSW010000093          891 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUGSW010000093 DAUGSW010000000
VERSION     DAUGSW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.093"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..>891)
                     /locus_tag="VIB18_001639"
     CDS             complement(<1..>891)
                     /locus_tag="VIB18_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEQ8766615.1"
                     /translation="GTMVLLLIQAFNYDFSHLRKKKLNQRTRTIISIANFSMILYFIT
                     IPMIDFIEEVENINFTHYQEMITAIYFLLFICFVNLLDRNLRQELQKQVVLQKELQLQ
                     NMARYSKQIEGLYQNIRSFRHDYANILTSLKIGIDCKDIEMISSIYHKVLKDSGKVLR
                     GEKFNLARLRNINDLPLKSLLFVKLSEAQRLSIPVSIEIGEPISIKNIELIDFLTLVS
                     ILIDNAIEGAAESGIVLCFFEQFGKQILIVQNDTFEKQINLSTIFERGVSSKGNNRGV
                     GLSNVREILESYPTVTLKTV"
BASE COUNT          301 a          154 c          120 g          316 t
ORIGIN      
        1 ttactgtttt gagggtaaca gtgggatatg attctaatat ctccctaaca tttgataaac
       61 caactcccct attatttcct tttgaagaaa cacctcgctc aaaaatcgtg gaaagattaa
      121 tctgtttttc aaaagtatca ttttgaacaa ttaatatctg tttaccaaat tgttcaaaaa
      181 aacaaagaac tattcccgac tctgctgcac cttcgattgc attatctatc aagatagaaa
      241 caagggttaa aaaatcgatt aactcaatgt tttttataga aatcggttcc ccaatttcta
      301 tagatacagg tatggataag cgttgagctt ctgataattt aacaaacagt aaacttttca
      361 gaggaaggtc gtttatattt ctcagccttg ctagattgaa tttttctccc cttaaaacct
      421 tccctgaatc tttcaacacc ttatgataaa tgcttgaaat catttcaata tctttgcaat
      481 caatgcctat tttcaagctt gttaaaatat ttgcataatc atgtctaaaa cttctgatat
      541 tttgatacag tccttcgatt tgcttactat agcgagccat attctgtaat tgtaactctt
      601 tttgtagaac aacttgcttt tgtaattctt ggcgtaagtt ccgatccaat aaatttacaa
      661 aacaaataaa taaaagaaaa taaattgctg ttatcatctc ttgatagtgc gtaaaattaa
      721 tattttcaac ttcttcgata aaatctatca ttggaatggt aataaagtac aatatcatgc
      781 taaagttggc aatagatata atcgttctag tacgttgatt tagtttcttt tttcttaaat
      841 gactaaagtc ataattaaaa gcttgaatca gcagcaaaac catagtacca g
//
LOCUS       DAUGSW010000094          867 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUGSW010000094 DAUGSW010000000
VERSION     DAUGSW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.094"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..>867
                     /locus_tag="VIB18_001640"
     CDS             <1..>867
                     /locus_tag="VIB18_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEQ8766616.1"
                     /translation="LLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAINKLLCKAKNI
                     NATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNILKINKKATIVIKSTVPI
                     GFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNESRNSQLFLDILTDISV
                     EKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIEAMGYDQR
                     IGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKMILNSS
                     AKTIGIYRINSK"
BASE COUNT          322 a          132 c          134 g          279 t
ORIGIN      
        1 ggctcctact tgcaaaggaa cacgacgtta ccttttttga tattgataat aaaaaaattg
       61 atttaataaa taaaaggcaa tcccctctta aagaagcagc tataaacaaa cttttatgta
      121 aggcaaaaaa tattaatgca acttcttctg aagaattagc atataaggat gcgactttca
      181 taatcttgtc tttgccaacc aacctaaaat ttaataagct tgatacttcc attatcgaaa
      241 tttctgtaag taatatttta aagataaaca aaaaggctac aattgtaata aagtcgacag
      301 ttccaattgg ttttacagaa tatttaagga atcgatttca ctacaacgat atcatttttt
      361 cacctgagtt ccttagggaa ggatcaacta ttcatgatca attgtatcct tcgagaacta
      421 tagttggaaa tgaatctaga aattctcaat tattcttaga catactaaca gatatatcgg
      481 ttgaaaaaga ctcgccatct ttattagttg gctcttctga agcagaagcg ataaagttat
      541 tttcgaatgc atacttggca caaaaaattg ctttttttaa tgagttggat acgtttgctg
      601 aaatgcaaaa tttggactca aaaaaaatta ttgaggctat gggatatgac cagagaatag
      661 gaaattcgca caataatcct tctttcggtt ttggtgggta ctgtcttcct aaggatatta
      721 agcaattaga gtatcatttt aaagaaattc cagcaccaat tattaccagt ataagtgagt
      781 ctaatttatt aagaaaaatt catatagcaa aaatgatttt gaacagctca gctaaaacaa
      841 taggaattta tagaattaat tccaaaa
//
LOCUS       DAUGSW010000095          784 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUGSW010000095 DAUGSW010000000
VERSION     DAUGSW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.095"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            110..>784
                     /locus_tag="VIB18_001641"
     CDS             110..>784
                     /locus_tag="VIB18_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8766617.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRLSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNL"
BASE COUNT          288 a          126 c          127 g          243 t
ORIGIN      
        1 tttactaaca ctagaatccc gacaattaag tcaaaaaaag ttatcactca cctaacctga
       61 ataaaaatgg tataatcgta aggatcacac tatttattaa ggaaacatta tgaaaattgt
      121 tcagggagta caacttcatc tgattaagac caaacagttt aaaaccaatc atattacctt
      181 tcgtctttca ggtgatttga accaaaaaac agtagcaaaa agagtcttag tggcacagat
      241 gttagcaaca gctaatgagt gttatccaac tgttaggcag tttagagaaa aattagcacg
      301 actttatgga gctagcttgt caactaacgt gttaacaaaa gggttagttc atattgtgga
      361 tatcgatatt acttttattc aagatagata tgcttgcaat ggggaaaaaa tactagatga
      421 aatgattcag tttttaaaag atatcttgtt ctcaccccta ttatccatcg cccagtatca
      481 gcctaaagtt tttgagactg aaaaaaataa tttgattaac tacatcgagt cagatagaga
      541 ggattctttt tactacagct ctcttaaggt aaaagaattg ttttattgta ataagaatct
      601 acaaatgtca gaatatggta gcccagaact aattgcaaaa gagactgcct atactagcta
      661 tcaagaattt cataaaatgc tcaatgaaga tcagattgat attttcattt taggagattt
      721 tgatgattat cgcgttgttc agctaattca tcaatttcca cttgataacc gaaataaaaa
      781 ccta
//
LOCUS       DAUGSW010000096          783 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUGSW010000096 DAUGSW010000000
VERSION     DAUGSW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.096"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..683
                     /locus_tag="VIB18_001642"
     CDS             <1..683
                     /locus_tag="VIB18_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8766618.1"
                     /translation="KILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFKGY
                     DLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKPFS
                     LKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYREY
                     EILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKTIR
                     GIGYKWDV"
BASE COUNT          270 a           94 c          154 g          265 t
ORIGIN      
        1 ataagatttt agccatagat gatgataaag aaattctgaa gcttatgaag actgctttgg
       61 agattgaaaa ttatcatgtt ataacctgtc aagagataga attaccaata gtttttgatg
      121 attttaaagg atatgatttg atcttattgg atatcatgat gcctaatata agtggaactg
      181 agttttgtta taaaattcgg gaagaagttc attctccaat tatttttgtt agcgctttag
      241 atggcgataa tgaaattgtc caagctttaa atataggggg agacgatttt attgtgaaac
      301 catttagctt aaaacaattc gtagctaaag ttaactctca tttgaagaga gaagagagag
      361 caaagataaa gaatgaggct gaggagagag tgaagcgcag ttttccacct atagaaatct
      421 atctagagga acgtatgtta tatattgata aacagccgtt attcctgact tatagagagt
      481 acgaaatttt agaattactg tcacgtcatc cgtataaagt tttcacaaaa gaagagatat
      541 atgaacaagt atatagcgat gaagcttcag cattgtttca ttctatttca gaatatatct
      601 atcagattag aatgaaattt tcaagttttg gaattaatcc aataaaaact attcgcggga
      661 ttggttataa atgggatgtt taaaaaatat tcaataaaaa atcgtgtttg gcgcgccgtc
      721 gttgaaattg tctttggagt ttgtatcact gttttaatga ttgcgataat atcgctttct
      781 ttt
//
LOCUS       DAUGSW010000097          722 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUGSW010000097 DAUGSW010000000
VERSION     DAUGSW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..722
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.097"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(3..76)
                     /locus_tag="VIB18_001643"
     tRNA            complement(3..76)
                     /locus_tag="VIB18_001643"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40..42),aa:Arg,seq:acg)
     gene            complement(93..177)
                     /locus_tag="VIB18_001644"
     tRNA            complement(93..177)
                     /locus_tag="VIB18_001644"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(141..143),aa:Leu,seq:taa)
     gene            complement(186..257)
                     /locus_tag="VIB18_001645"
     tRNA            complement(186..257)
                     /locus_tag="VIB18_001645"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(223..225),aa:Gly,seq:gcc)
     gene            complement(270..342)
                     /locus_tag="VIB18_001646"
     tRNA            complement(270..342)
                     /locus_tag="VIB18_001646"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(307..309),aa:Thr,seq:tgt)
     gene            complement(353..434)
                     /locus_tag="VIB18_001647"
     tRNA            complement(353..434)
                     /locus_tag="VIB18_001647"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(398..400),aa:Leu,seq:tag)
     gene            complement(440..512)
                     /locus_tag="VIB18_001648"
     tRNA            complement(440..512)
                     /locus_tag="VIB18_001648"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(477..479),aa:Lys,seq:ttt)
     gene            complement(544..616)
                     /locus_tag="VIB18_001649"
     tRNA            complement(544..616)
                     /locus_tag="VIB18_001649"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(581..583),aa:Asp,seq:gtc)
     gene            complement(634..706)
                     /locus_tag="VIB18_001650"
     tRNA            complement(634..706)
                     /locus_tag="VIB18_001650"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(671..673),aa:Val,seq:tac)
BASE COUNT          186 a          207 c          159 g          170 t
ORIGIN      
        1 gatgcaccct agaggagtcg aacctctaac cgcctgattc gtagtcaggt actctatcca
       61 gttgagctaa gggtgctatt tcaaaaaatt aatgccgagg accggaatcg aaccggtacg
      121 atgtaaacca tcgcaggatt ttaagtcctg tgcgtctgcc agttccgcca ccccggctcc
      181 tcaaaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt gatgttctac
      241 cactgaacta cgttcgcaac taatctcaat gccggctaca tgacttgaac acgcgaccct
      301 ctgattacaa atcagatgct ctaccaactg agctaagccg gctaatcttt tatgcgggtt
      361 aagggacttg aacccccacg ccgttaagcg ccagatccta aatctggtgc gtctgccaat
      421 tccgccaaac ccgcttttat gacccgtact gggctcgaac cagtgaccca ttgattaaaa
      481 gtcaattgct ctaccaactg agctaacgag tctttccttc aaaaaatatg actactcttt
      541 gaacggtccc gacgggaatc gaacccgcga tcttcgccgt gacagggcga cgtgataacc
      601 gctacactac gggacctgta ttttccaata ctatgggagt taacgggatc gaaccgctga
      661 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcccattg agtgtgtcat
      721 ta
//
LOCUS       DAUGSW010000098          676 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUGSW010000098 DAUGSW010000000
VERSION     DAUGSW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..676
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.098"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(221..634)
                     /locus_tag="VIB18_001651"
     CDS             complement(221..634)
                     /locus_tag="VIB18_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8766619.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
BASE COUNT          242 a          127 c           94 g          213 t
ORIGIN      
        1 gtcattataa cactgtaaga gtttatcgtc aaatattttg cttttcctat agttattcta
       61 ttaaaaaact tcgacaagat tactccaaaa attgctcttc actttgaaag ttaaccaaat
      121 catttaacga tcaaaagaga ttaatcaagc aaaagaagat acaacaaata actattttta
      181 acgagtttaa tagcacgatc cagtcgttaa cctaataagt ctattcatgt aattctaaag
      241 gcaaaccatc cggatcaaaa aagaaagtca ttttctcacc tgtgtaatca tcatgcctaa
      301 taggctccac tggaattcct aagctcttta gatcatctac ataactctca atgttggtaa
      361 cacgaaaagc aaggtgtctc aaaccacagg cctcactttt aaattctggt tgacttacac
      421 gtttaggagg agcttgatag taggggtcac ttgtcacctt accaaaaatc tccaattcaa
      481 tacgaccaca agataaatct aatttgtaat catgcttgtc aggacgataa ttttctctga
      541 taatttcaaa tccgagttta ttcacataaa aatcttttga cagatgataa tcagatacaa
      601 taatagcaac gtgatgaatg gcatttagtt tcatcatatt tctcctttca aaaaaagtag
      661 gatgagataa attttc
//
LOCUS       DAUGSW010000099          662 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUGSW010000099 DAUGSW010000000
VERSION     DAUGSW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.099"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(142..324)
                     /locus_tag="VIB18_001652"
     CDS             complement(142..324)
                     /locus_tag="VIB18_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8766620.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
     gene            complement(339..584)
                     /locus_tag="VIB18_001653"
     CDS             complement(339..584)
                     /locus_tag="VIB18_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ8766621.1"
                     /translation="MIKFAEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGA
                     GMATLGVGGVAGAFAGAHVGAIAGGLTCVGGMLFNGK"
BASE COUNT          233 a          160 c           61 g          208 t
ORIGIN      
        1 tttgtaatag tacttagtaa gacataaaca aatatcacaa ttaaaattac tttacttgca
       61 ttttctctta cctctttatc cttcaaaaaa atttgggaaa gtattagaca aattaaaccg
      121 agtattataa ctataatcat atcattgata agctgcaatt ccagatgcta cacatacaaa
      181 tgctgccgca cctccagtta ttggacctcc tgctgcagct ataagcatcc cacctaagca
      241 ccctccgata gcagatccaa tatttccttt tccaccagaa atatttacta attcttcaaa
      301 ctgtaattct aaaaaattat ccatttttca cctcaaaatt attttccatt aaataacata
      361 ccaccaacgc aagttaatcc acccgcaata gcacctacat gtgcacctgc aaacgcacct
      421 gcaactcctc caacacctaa agtagccata cctgctccaa caccacctgc aatagcacct
      481 gaagtaatac caccaattaa atgattttta caatctgtag cactataacc tccaataata
      541 tggaacaact cttctttttg tatttcttct gcaaatttta tcataacttt aaaaaccttt
      601 ctaaaatgtt atattcatct tgttgcaact ttgacaaact aaatatagca tattattata
      661 aa
//
LOCUS       DAUGSW010000100          637 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUGSW010000100 DAUGSW010000000
VERSION     DAUGSW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.100"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..411)
                     /locus_tag="VIB18_001654"
     CDS             complement(<1..411)
                     /locus_tag="VIB18_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ8766622.1"
                     /translation="MHNEKNNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEEHLYRYFKTKFSSYL
                     KDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLW"
     gene            complement(407..480)
                     /locus_tag="VIB18_001655"
     tRNA            complement(407..480)
                     /locus_tag="VIB18_001655"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(444..446),aa:Arg,seq:acg)
     gene            complement(560..633)
                     /locus_tag="VIB18_001656"
     tRNA            complement(560..633)
                     /locus_tag="VIB18_001656"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(597..599),aa:Asn,seq:gtt)
BASE COUNT          185 a          153 c           95 g          204 t
ORIGIN      
        1 ccataaccct ctcgatggaa tggcatgtgc aacctcccct atctcttcat atgctaactt
       61 atggaactga cgcttttgac tttcttgacg gcgtaataaa tctttcaaat aagatgaaaa
      121 ttttgtttta aaatagcgat ataaatgctc ttcttcctca attaactctg ggtacctttc
      181 tagtaactgt aataagataa tatgtccttc ttgtaaccag tcatctctat cccacaattg
      241 aatataatag tgtcgcttta atttcaaaat aatgggctta actttttcaa acgctgctct
      301 tgtctctatc gacattttga gtctcctttt ctttttaact atccctagta taaagagaac
      361 cacaaaaaaa caacaggaca ctaatgtcct gttgtttttt tcattatgca ccctagagga
      421 gtcgaacctc taaccgcctg attcgtagtc aggtactcta tccagttgag ctaagggtgc
      481 caacgcatat cttgcctcta tcttaccaca ctcttctcta aaatgcaaaa aaagatagga
      541 cgcttcctac ctctctctac tccgccagta ggactcgaac ctacgacatc atgattaaca
      601 gtcatgcgct actaccaact gagctatggc ggataaa
//
LOCUS       DAUGSW010000101          516 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUGSW010000101 DAUGSW010000000
VERSION     DAUGSW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.101"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(<1..>516)
                     /locus_tag="VIB18_001657"
     CDS             complement(<1..>516)
                     /locus_tag="VIB18_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ8766623.1"
                     /translation="AIELMTTLGEIALGSQTIFNILFMPAFVMNLLILFFRPYITQMA
                     IALIRGQIKEFNKIQVQLFAYLGVFSLIALVGSGLFGIPFLSMLYGTNLTDYWVDFML
                     IMLGGSIGSFATVIDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSF
                     LITMLVWLGLS"
BASE COUNT          213 a           95 c           68 g          140 t
ORIGIN      
        1 atggataatc ccaaccaaac caacattgtt attaaaaagc tcaaagcagc tcctaaaata
       61 tgatatttca taacaaaaag attggtaatt aataacgaaa tcaaaaatcc tcctgtatat
      121 ggaataagaa gaagttgctg ttttctcata gcggttaaga tattatcgat aactgtcgca
      181 aaactaccaa tcgagcctcc tagcataatc aacataaagt ctacccaata atccgtaagg
      241 ttagtaccat atagcattga taaaaaggga ataccaaaca aaccacttcc aactaacgct
      301 atcagtgaaa aaactcctaa ataagcaaac aattgaactt gtatcttatt aaactctttt
      361 atttgacctc tgattaaagc aatagccatc tgtgtaatat aaggtctaaa aaataaaatt
      421 agcaaattca taacaaaggc tggcataaat aaaatattaa aaattgtttg agagcccaaa
      481 gcaatttcac ctaaagtcgt cattagttca atagcg
//
LOCUS       DAUGSW010000102          480 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUGSW010000102 DAUGSW010000000
VERSION     DAUGSW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.102"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            117..342
                     /locus_tag="VIB18_001658"
                     /pseudo
     CDS             117..342
                     /locus_tag="VIB18_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987967.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          169 a           64 c           91 g          156 t
ORIGIN      
        1 aataaacaaa taggagggca attgtttaac tggttaatta gaatttttgt tattttcagg
       61 aagatactca gggctttttt ataagttgat gtattaacaa aagataaaga ggtttcatga
      121 cttattttag attaaaaaaa gaattaaact ggttactaag aagtaaagga attgtagttt
      181 acgaagggaa tcaaaaactt cagatagcca ttaatacagg taaaaataac agtgaaaaaa
      241 gtcttttttg atactttttt tgaggtggtt cgggcggcag cgactttctc cacagcaaaa
      301 aacatctgtt ttggtcttgg cttacttcgt tcgcagaaat aggaaatcgg gtatcacatt
      361 agcagagtag ttcatgcttt ttgagcatca cactgggtct gtctacgttc taaaagcttt
      421 tgtcattttt gtatcatacc ccctacaagt agaaaaagca taataaagaa aatttataaa
//
LOCUS       DAUGSW010000103          456 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUGSW010000103 DAUGSW010000000
VERSION     DAUGSW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.103"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            <1..421
                     /locus_tag="VIB18_001659"
     CDS             <1..421
                     /locus_tag="VIB18_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEQ8766624.1"
                     /translation="IDYHYYLTTTGSCIDFGEEGAVGRGNKTHGIISSFRPNTMEAPA
                     GKNCTYFVGKVWGFLSDTIAKEIYEAFNTPCQIIMQLNIGSKLYRPTHLFIQTEESVD
                     QERVLEIVNRHLNNGKQNTNLILSTQHFIPKTNVYDG"
BASE COUNT          160 a           57 c           78 g          161 t
ORIGIN      
        1 tattgattac cattattatt taactactac aggttcttgt attgattttg gagaagaagg
       61 tgcagttggt cgaggtaata aaactcatgg tatcatatca agttttaggc caaatactat
      121 ggaagcacca gctggaaaaa attgtactta ttttgtagga aaggtttggg gatttttgtc
      181 tgatactatt gccaaagaaa tttatgaagc attcaatact ccctgtcaaa tcattatgca
      241 attaaatatt ggatcaaaat tgtatagacc aacccattta tttattcaga cagaagaaag
      301 tgttgatcaa gaaagagtat tagaaattgt taacaggcat ttaaataatg gtaaacaaaa
      361 tactaattta atcttgtcaa ctcaacattt tattcctaaa accaatgttt atgatggata
      421 aaactgtttt atattttggg ttggttgaaa tttctt
//
LOCUS       DAUGSW010000104          427 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00060534
            SAMN33608796-rid17957453.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUGSW010000104 DAUGSW010000000
VERSION     DAUGSW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608796
            Sequence Read Archive: SRR23751527
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723290.1
            Genome Coverage       :: 178x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:24:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,663
            CDSs (total)                      :: 1,624
            Genes (coding)                    :: 1,579
            CDSs (with protein)               :: 1,579
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 21 of 45
            Pseudo Genes (internal stop)      :: 13 of 45
            Pseudo Genes (multiple problems)  :: 19 of 45
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608796-rid17957453.denovo.104"
                     /strain="AUSMDU00060534"
                     /serotype="EMM77.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST572"
     gene            complement(64..137)
                     /locus_tag="VIB18_001660"
     tRNA            complement(64..137)
                     /locus_tag="VIB18_001660"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(101..103),aa:Met,seq:cat)
     gene            complement(147..236)
                     /locus_tag="VIB18_001661"
     tRNA            complement(147..236)
                     /locus_tag="VIB18_001661"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(198..200),aa:Ser,seq:tga)
     gene            complement(259..332)
                     /locus_tag="VIB18_001662"
     tRNA            complement(259..332)
                     /locus_tag="VIB18_001662"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(296..298),aa:Ile,seq:cat)
     gene            complement(353..426)
                     /locus_tag="VIB18_001663"
     tRNA            complement(353..426)
                     /locus_tag="VIB18_001663"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(390..392),aa:Met,seq:cat)
BASE COUNT          114 a          120 c           98 g           95 t
ORIGIN      
        1 atggagcttc aatccattgc tctaccaact gagctaccga gccaacaact acatacttat
       61 gtattgcggg agcaggattt gaacctacga ccttcgggtt atgagcccga cgagctacct
      121 aactgctcca tcccgcgata gttaaaagga ggatgtggga ttcgaaccca cgcacgcttt
      181 tacacgcctg acggttttca agaccgttcc cttcagccgg acttgggtaa tcctccaaaa
      241 taatgattat ctatgatatg gaccttgtag gactcgaacc tacgaccgct cggttatgag
      301 ccgagtgctc taaccagttg agctaaaggt cccaagtcat ccataaaaat aatagcggcg
      361 aaggggatcg aacccccgac ctcccgggta tgaaccggac gctctagcca gctgagctac
      421 accgcca
//
